# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- PT PF04886.12 ETS72872.1 - 1.3e-08 34.3 25.8 9.9e-08 31.4 25.8 2.2 1 1 0 1 1 1 1 PT repeat Dimer_Tnp_hAT PF05699.14 ETS72873.1 - 3.5e-15 55.5 0.0 1e-13 50.9 0.0 2.9 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 ETS72873.1 - 0.00098 19.0 0.0 0.003 17.5 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) DUF4413 PF14372.6 ETS72873.1 - 0.035 14.5 1.5 0.059 13.7 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) OrsD PF12013.8 ETS72874.1 - 1.7e-27 96.2 4.3 1.7e-27 96.2 4.3 2.2 3 0 0 3 3 3 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 ETS72874.1 - 1.4 10.0 5.7 20 6.4 0.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DEAD PF00270.29 ETS72875.1 - 1.2e-12 48.0 0.0 2.5e-12 46.9 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ETS72875.1 - 0.00043 20.3 0.0 0.001 19.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 ETS72875.1 - 0.036 12.8 0.0 0.058 12.1 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Thioredoxin_6 PF13848.6 ETS72876.1 - 2.1e-21 76.6 0.0 1.8e-17 63.9 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 ETS72876.1 - 1.8e-06 27.9 0.0 0.00083 19.3 0.0 3.3 4 0 0 4 4 4 1 Thioredoxin Methyltr_RsmB-F PF01189.17 ETS72877.1 - 5.9e-17 62.0 0.0 1.7e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F DUF1996 PF09362.10 ETS72878.1 - 3.8e-64 216.9 0.2 5.8e-64 216.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Aminotran_3 PF00202.21 ETS72879.1 - 3.5e-69 233.4 0.0 4.5e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III SnoaL_4 PF13577.6 ETS72880.1 - 9.9e-13 48.3 0.4 1.2e-12 48.1 0.4 1.1 1 0 0 1 1 1 1 SnoaL-like domain CMD PF02627.20 ETS72881.1 - 0.078 13.0 0.0 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family ADH_N PF08240.12 ETS72882.1 - 8.1e-25 86.8 3.2 1.4e-24 86.1 3.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS72882.1 - 1e-07 32.0 0.2 1.8e-07 31.2 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ETS72882.1 - 0.069 12.5 0.4 0.12 11.7 0.4 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ETS72882.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Xpo1 PF08389.12 ETS72883.1 - 1.9e-31 109.1 4.8 3.2e-31 108.4 0.1 3.7 5 0 0 5 5 5 1 Exportin 1-like protein HEAT PF02985.22 ETS72883.1 - 0.0029 17.7 0.1 23 5.6 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat DUF4844 PF16133.5 ETS72883.1 - 0.0084 16.6 0.5 1.2 9.7 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4844) EF-G-binding_N PF07299.11 ETS72883.1 - 0.014 15.9 0.4 1.1 9.8 0.0 3.8 4 0 0 4 4 4 0 Elongation factor G-binding protein, N-terminal Peptidase_M18 PF02127.15 ETS72885.1 - 4.6e-170 566.1 0.0 1.8e-169 564.1 0.0 1.7 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 ETS72885.1 - 1.1e-07 31.2 0.3 0.00019 20.6 0.0 3.1 3 0 0 3 3 3 3 M42 glutamyl aminopeptidase DUF4471 PF14740.6 ETS72886.1 - 0.054 12.7 6.4 0.13 11.5 6.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Afi1 PF07792.12 ETS72886.1 - 0.15 12.5 15.9 0.59 10.6 15.9 2.0 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PPL5 PF18168.1 ETS72886.1 - 0.43 9.8 8.4 0.84 8.9 8.4 1.4 1 0 0 1 1 1 0 Prim-pol family 5 ABC2_membrane_2 PF12679.7 ETS72886.1 - 0.44 9.8 2.0 0.81 8.9 2.0 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein SpoIIP PF07454.11 ETS72886.1 - 0.47 9.9 15.3 1.4 8.4 15.3 1.7 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) V_ATPase_I PF01496.19 ETS72886.1 - 0.54 8.1 13.1 1.1 7.1 13.1 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec62 PF03839.16 ETS72886.1 - 1.1 8.7 7.5 3.4 7.1 7.5 1.8 1 0 0 1 1 1 0 Translocation protein Sec62 Slu7 PF11708.8 ETS72886.1 - 2.5 7.8 22.6 1.8 8.3 0.2 2.7 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor Plasmodium_Vir PF05795.11 ETS72886.1 - 2.6 7.4 7.7 6.6 6.0 7.7 1.7 1 0 0 1 1 1 0 Plasmodium vivax Vir protein ArfGap PF01412.18 ETS72886.1 - 6 7.0 12.4 4.8 7.3 9.3 2.6 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf MDM10 PF12519.8 ETS72886.1 - 6.3 5.5 11.2 1.6 7.5 7.7 1.7 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 ALMT PF11744.8 ETS72886.1 - 7.9 5.2 13.4 18 4.0 13.4 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter FAM60A PF15396.6 ETS72886.1 - 9.4 6.2 13.3 43 4.0 13.3 2.1 1 0 0 1 1 1 0 Protein Family FAM60A Whi5 PF08528.11 ETS72887.1 - 4.9e-06 26.0 0.3 8.7e-06 25.2 0.3 1.3 1 0 0 1 1 1 1 Whi5 like NUFIP2 PF15293.6 ETS72887.1 - 0.015 14.2 2.1 0.017 14.1 2.1 1.0 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 HEAT_2 PF13646.6 ETS72888.1 - 5.5e-13 49.1 10.8 0.018 15.4 0.0 7.8 6 2 1 7 7 7 4 HEAT repeats HEAT PF02985.22 ETS72888.1 - 1.4e-07 31.2 24.5 0.064 13.6 0.0 10.8 11 0 0 11 11 11 2 HEAT repeat Vac14_Fab1_bd PF12755.7 ETS72888.1 - 1.6e-07 31.8 0.0 0.0063 17.1 0.0 4.7 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 ETS72888.1 - 4.7e-05 23.1 0.5 2.5 7.6 0.0 4.8 4 0 0 4 4 4 3 CLASP N terminal HEAT_EZ PF13513.6 ETS72888.1 - 0.036 14.6 23.2 0.42 11.2 0.0 8.0 9 0 0 9 9 9 0 HEAT-like repeat Myf5 PF12232.8 ETS72888.1 - 0.17 12.6 1.5 0.76 10.6 0.0 3.0 2 0 0 2 2 2 0 Myogenic determination factor 5 Transcrip_reg PF01709.20 ETS72889.1 - 1.1e-66 224.7 0.8 1.3e-66 224.5 0.8 1.0 1 0 0 1 1 1 1 Transcriptional regulator Pet100 PF09803.9 ETS72890.1 - 4.5e-12 46.3 0.2 5.8e-12 45.9 0.2 1.1 1 0 0 1 1 1 1 Pet100 Nitr_red_bet_C PF14711.6 ETS72890.1 - 0.072 12.8 0.3 0.098 12.4 0.3 1.2 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal Glyco_transf_22 PF03901.17 ETS72891.1 - 7.4e-62 209.9 22.0 9e-62 209.6 22.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Wzy_C PF04932.15 ETS72891.1 - 0.25 11.0 4.4 1.1 8.9 1.9 2.6 2 0 0 2 2 2 0 O-Antigen ligase Phosphodiest PF01663.22 ETS72892.1 - 6.2e-15 55.6 1.1 1.8e-09 37.7 0.2 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ETS72892.1 - 3.7e-05 23.3 0.0 0.00056 19.4 0.0 2.1 2 0 0 2 2 2 1 Sulfatase DUF423 PF04241.15 ETS72892.1 - 0.34 11.1 2.2 0.66 10.2 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF423) DUF2157 PF09925.9 ETS72892.1 - 4.6 7.0 13.8 11 5.9 4.6 3.6 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) RRM_1 PF00076.22 ETS72894.1 - 2.8e-57 190.5 0.0 1.2e-17 63.5 0.0 6.2 6 1 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 ETS72894.1 - 5e-05 23.1 0.1 0.12 12.2 0.1 2.8 2 1 1 3 3 3 2 Rrp7 RRM-like N-terminal domain PHM7_cyt PF14703.6 ETS72894.1 - 0.00023 21.5 0.0 17 5.6 0.0 5.4 5 2 1 6 6 6 2 Cytosolic domain of 10TM putative phosphate transporter DbpA PF03880.15 ETS72894.1 - 0.0045 17.0 0.3 1.4 8.9 0.0 2.9 3 0 0 3 3 3 2 DbpA RNA binding domain RRM_7 PF16367.5 ETS72894.1 - 0.0091 16.1 0.0 13 6.0 0.0 3.7 3 0 0 3 3 3 1 RNA recognition motif Smg4_UPF3 PF03467.15 ETS72894.1 - 1.1 9.3 14.8 15 5.5 0.0 5.5 4 2 1 5 5 5 0 Smg-4/UPF3 family Cnd3 PF12719.7 ETS72895.1 - 7e-93 311.0 2.1 1.3e-92 310.1 0.3 2.3 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 ETS72895.1 - 4.4e-10 39.8 13.2 1.3e-06 28.7 1.2 5.2 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.22 ETS72895.1 - 3.6e-07 29.9 12.8 0.08 13.2 0.0 7.9 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.7 ETS72895.1 - 2.1e-05 24.6 6.6 0.22 11.6 0.1 5.5 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ETS72895.1 - 0.0049 17.4 0.8 0.0049 17.4 0.8 5.7 7 1 0 7 7 7 1 HEAT-like repeat EGF_2 PF07974.13 ETS72896.1 - 0.00079 19.7 10.5 0.0015 18.9 10.5 1.5 1 0 0 1 1 1 1 EGF-like domain EB PF01683.18 ETS72896.1 - 0.008 16.4 8.2 0.015 15.6 8.2 1.3 1 0 0 1 1 1 1 EB module EGF_Tenascin PF18720.1 ETS72896.1 - 0.75 9.9 10.2 1.5 9.0 10.2 1.5 1 0 0 1 1 1 0 Tenascin EGF domain I-EGF_1 PF18372.1 ETS72896.1 - 1.6 8.9 8.1 0.54 10.4 5.2 1.7 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 p450 PF00067.22 ETS72897.1 - 4.9e-77 259.6 0.0 6.3e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 ETS72898.1 - 1.9e-24 86.2 0.1 2.5e-19 69.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS72898.1 - 1.8e-13 50.6 0.1 2.3e-12 47.0 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS72898.1 - 1.6e-07 31.4 0.1 2.7e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ETS72898.1 - 0.041 13.8 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding adh_short_C2 PF13561.6 ETS72899.1 - 2.6e-60 203.9 2.6 6.4e-60 202.6 2.6 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS72899.1 - 1e-50 171.9 3.4 1.9e-50 171.0 3.4 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS72899.1 - 2.5e-08 34.0 1.4 1e-07 32.1 1.4 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS72899.1 - 0.0043 16.5 0.2 0.057 12.9 0.2 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 ETS72899.1 - 0.065 13.1 3.2 2.4 7.9 3.2 2.3 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Glyco_hydro_35 PF01301.19 ETS72900.1 - 1.7e-76 257.9 0.6 2.5e-76 257.3 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 ETS72900.1 - 4.3e-48 162.6 1.5 2.3e-30 105.5 0.0 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 ETS72900.1 - 1.4e-47 161.9 0.0 2.5e-47 161.1 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 ETS72900.1 - 4.1e-22 77.5 0.1 1.1e-21 76.2 0.1 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 ETS72900.1 - 0.00068 19.1 1.0 0.014 14.8 0.1 2.8 2 1 1 3 3 3 1 Cellulase (glycosyl hydrolase family 5) Cys_Met_Meta_PP PF01053.20 ETS72901.1 - 3.2e-57 193.8 0.0 7.9e-57 192.5 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Polysacc_deac_1 PF01522.21 ETS72902.1 - 2.4e-25 88.8 0.0 3.4e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase GGDEF_2 PF17853.1 ETS72902.1 - 0.082 13.2 0.1 0.98 9.7 0.1 2.3 2 0 0 2 2 2 0 GGDEF-like domain Ribonuc_2-5A PF06479.12 ETS72902.1 - 0.19 11.9 0.0 16 5.7 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease 2-5A Glyco_hydro_3_C PF01915.22 ETS72903.1 - 2.3e-44 151.8 0.0 3e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ETS72903.1 - 0.0035 17.4 0.0 0.0057 16.7 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Sporozoite_P67 PF05642.11 ETS72903.1 - 0.026 12.6 5.8 0.028 12.5 5.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_3 PF00933.21 ETS72904.1 - 2.8e-23 82.8 0.0 4.7e-23 82.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain CorA PF01544.18 ETS72906.1 - 0.13 11.6 7.3 0.14 11.4 4.9 2.4 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Jnk-SapK_ap_N PF09744.9 ETS72906.1 - 0.6 10.3 4.3 0.33 11.2 1.5 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 APH PF01636.23 ETS72907.1 - 9.5e-05 22.4 0.1 0.051 13.5 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 ETS72907.1 - 0.0013 18.1 0.0 0.8 9.0 0.0 3.1 2 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS72907.1 - 0.11 11.8 0.0 5.7 6.1 0.0 2.9 3 0 0 3 3 3 0 Protein tyrosine kinase Glyco_hydro_3_C PF01915.22 ETS72908.1 - 1.9e-48 165.1 0.0 3.4e-48 164.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS72908.1 - 9.7e-39 133.6 0.0 1.7e-38 132.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS72908.1 - 2.6e-24 85.1 0.1 4.6e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Ser_hydrolase PF06821.13 ETS72908.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Glyco_hydro_16 PF00722.21 ETS72910.1 - 5.7e-08 32.4 0.0 8.4e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 ETS72910.1 - 3.4e-06 25.7 0.8 0.01 14.3 0.9 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) WD40 PF00400.32 ETS72912.1 - 6.9e-15 55.2 10.3 0.011 16.6 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS72912.1 - 9.1e-07 29.1 0.3 0.0023 18.2 0.2 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ETS72912.1 - 1.3e-05 24.1 5.1 2.4e-05 23.2 0.9 3.1 2 2 1 4 4 4 1 Nucleoporin Nup120/160 HA2 PF04408.23 ETS72913.1 - 1.9e-21 76.4 0.0 1.9e-21 76.4 0.0 2.8 4 0 0 4 4 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ETS72913.1 - 3.5e-17 62.5 0.0 1.8e-16 60.3 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ETS72913.1 - 4.3e-13 49.6 0.0 1e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ETS72913.1 - 3.6e-08 33.4 0.3 1.3e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ETS72913.1 - 6.3e-06 26.5 0.1 1.6e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ETS72913.1 - 2e-05 24.4 1.1 4.4e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 ETS72913.1 - 7.9e-05 22.0 0.0 0.00018 20.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 ETS72913.1 - 0.00038 20.8 0.1 0.00086 19.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 ETS72913.1 - 0.00054 19.6 0.3 0.0014 18.3 0.3 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 ETS72913.1 - 0.0012 18.8 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.15 ETS72913.1 - 0.0012 18.8 0.0 0.59 10.1 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ATPase PF06745.13 ETS72913.1 - 0.0068 15.8 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 KaiC T2SSE PF00437.20 ETS72913.1 - 0.034 13.2 0.0 0.095 11.7 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 ETS72913.1 - 0.053 14.0 0.1 0.29 11.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 ETS72913.1 - 0.056 13.9 1.8 0.34 11.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 ETS72913.1 - 0.1 12.7 0.3 0.67 10.0 0.3 2.2 1 1 0 1 1 1 0 AAA domain Glycos_transf_2 PF00535.26 ETS72914.1 - 9.3e-35 119.9 0.0 1.1e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ETS72914.1 - 4.2e-13 49.7 0.0 5.6e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ETS72914.1 - 3.5e-05 23.4 0.0 4.5e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ETS72914.1 - 0.0019 17.7 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 adh_short_C2 PF13561.6 ETS72915.1 - 5.7e-50 170.0 2.0 2.4e-47 161.5 2.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS72915.1 - 8.4e-45 152.6 1.6 1.1e-44 152.3 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS72915.1 - 7.9e-13 48.7 0.3 1.3e-12 48.1 0.3 1.3 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 ETS72915.1 - 0.032 14.3 0.5 0.05 13.7 0.5 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 ETS72915.1 - 0.041 13.8 0.5 0.068 13.1 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ETS72915.1 - 0.066 12.6 0.2 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CSN8_PSD8_EIF3K PF10075.9 ETS72916.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family MSA-2c PF12238.8 ETS72916.1 - 0.2 11.6 0.2 0.32 11.0 0.2 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Transp_cyt_pur PF02133.15 ETS72917.1 - 2.7e-73 247.2 45.8 3.1e-73 247.0 45.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Flavin_Reduct PF01613.18 ETS72918.1 - 1.8e-20 73.5 0.5 2.9e-20 72.9 0.5 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Asr PF06392.11 ETS72918.1 - 0.69 10.4 3.2 1.4 9.4 3.2 1.5 1 0 0 1 1 1 0 Acid shock protein repeat DUF5132 PF17195.4 ETS72919.1 - 0.16 12.1 0.1 0.35 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF5132) DUF1749 PF08538.10 ETS72920.1 - 4.3e-97 324.8 0.0 5.3e-97 324.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 ETS72920.1 - 1e-05 26.3 0.7 1.4e-05 25.9 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ETS72920.1 - 5.3e-05 23.0 0.1 8.9e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.12 ETS72920.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) MFS_1 PF07690.16 ETS72921.1 - 2.4e-19 69.5 56.0 9.9e-18 64.2 53.0 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 ETS72922.1 - 3.8e-43 147.8 55.3 3.8e-43 147.8 55.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS72922.1 - 3.8e-20 71.9 19.7 6.3e-20 71.1 19.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS72922.1 - 2.4e-17 63.0 5.9 2.4e-17 63.0 5.9 2.8 1 1 2 3 3 3 2 Sugar (and other) transporter Ank_2 PF12796.7 ETS72923.1 - 7e-22 77.8 2.1 6.9e-10 39.4 0.1 5.2 3 1 3 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS72923.1 - 4e-13 49.6 7.2 9.1e-05 22.9 0.1 6.5 5 1 1 6 6 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS72923.1 - 5.6e-12 45.7 2.0 9e-05 22.7 0.0 5.2 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS72923.1 - 1.2e-11 43.7 5.3 0.027 15.0 0.0 7.2 7 0 0 7 7 6 3 Ankyrin repeat NACHT PF05729.12 ETS72923.1 - 2e-09 37.6 0.1 5.3e-09 36.2 0.1 1.7 1 0 0 1 1 1 1 NACHT domain Ank PF00023.30 ETS72923.1 - 7.4e-08 32.5 2.0 0.0045 17.4 0.0 6.2 6 0 0 6 6 6 1 Ankyrin repeat AAA_16 PF13191.6 ETS72923.1 - 6.5e-07 29.9 0.0 2.2e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS72923.1 - 0.00022 21.5 0.1 0.0013 19.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ETS72923.1 - 0.00095 19.6 0.0 0.0034 17.8 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ETS72923.1 - 0.0023 18.3 0.1 0.02 15.3 0.0 2.6 3 0 0 3 3 3 1 RNA helicase AAA_18 PF13238.6 ETS72923.1 - 0.08 13.5 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ETS72923.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE adh_short PF00106.25 ETS72924.1 - 1.4e-20 73.6 0.0 1.3e-16 60.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 ETS72924.1 - 1.2e-06 28.5 0.1 2e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Beta-lactamase PF00144.24 ETS72925.1 - 7.2e-41 140.5 0.0 1e-40 140.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 ETS72925.1 - 0.034 13.7 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase enzyme family Sigma70_r1_2 PF00140.20 ETS72925.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 FAD_binding_3 PF01494.19 ETS72926.1 - 5.6e-12 45.6 0.2 4.8e-11 42.5 0.1 2.5 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS72926.1 - 1.3e-10 41.0 0.1 9.6e-05 21.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS72926.1 - 6.9e-08 32.0 0.0 1.7e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS72926.1 - 1.6e-05 24.7 0.1 0.0015 18.2 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ETS72926.1 - 4.4e-05 23.0 0.1 0.00043 19.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ETS72926.1 - 6.8e-05 21.9 0.3 0.1 11.4 0.0 2.6 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox PF00070.27 ETS72926.1 - 7.9e-05 23.1 0.1 0.0079 16.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS72926.1 - 0.00011 22.3 0.1 0.00077 19.6 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ETS72926.1 - 0.00018 20.4 0.1 0.0026 16.5 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 ETS72926.1 - 0.00097 18.3 0.1 0.27 10.2 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ETS72926.1 - 0.0016 17.8 0.0 0.0082 15.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS72926.1 - 0.0028 16.8 0.0 0.024 13.7 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 ETS72926.1 - 0.0099 15.9 0.4 4.3 7.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding MFS_1 PF07690.16 ETS72927.1 - 2.5e-34 118.8 30.4 3.8e-34 118.2 30.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sars6 PF12133.8 ETS72927.1 - 0.011 15.6 0.4 0.038 13.9 0.1 2.0 2 0 0 2 2 2 0 Open reading frame 6 from SARS coronavirus DUF5313 PF17240.2 ETS72927.1 - 0.079 13.4 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5313) T_cell_tran_alt PF15128.6 ETS72927.1 - 2.4 8.0 6.1 1.2 8.9 0.2 2.5 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Histidinol_dh PF00815.20 ETS72928.1 - 3.8e-139 464.2 0.1 4.5e-139 464.0 0.1 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase TipAS PF07739.13 ETS72928.1 - 0.094 13.3 0.1 0.24 11.9 0.1 1.7 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain ANAPC4_WD40 PF12894.7 ETS72928.1 - 0.11 12.8 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_S8 PF00082.22 ETS72929.1 - 3.1e-47 161.3 7.5 3.2e-47 161.3 4.9 2.1 2 0 0 2 2 2 1 Subtilase family fn3_5 PF06280.12 ETS72929.1 - 1.3e-06 29.1 0.1 7.2e-06 26.7 0.1 2.2 1 1 0 1 1 1 1 Fn3-like domain Runt PF00853.19 ETS72929.1 - 0.2 11.2 0.1 0.54 9.8 0.1 1.7 1 0 0 1 1 1 0 Runt domain UCH PF00443.29 ETS72931.1 - 2.9e-36 125.3 0.0 9.8e-32 110.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ETS72931.1 - 7.2e-08 32.4 2.7 3e-07 30.3 2.7 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Cytochrome_C7 PF14522.6 ETS72931.1 - 2.9 7.9 5.2 12 5.9 3.5 2.4 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c F_bP_aldolase PF01116.20 ETS72932.1 - 9.1e-91 304.2 0.0 1e-90 304.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Glyco_hydro_35 PF01301.19 ETS72933.1 - 3.2e-90 303.0 0.0 4.3e-90 302.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 ETS72933.1 - 2.8e-60 203.2 6.3 5e-60 202.4 6.3 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 ETS72933.1 - 6.1e-56 187.9 3.1 3e-30 105.1 0.1 3.2 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 ETS72933.1 - 1.2e-16 60.0 0.4 6.7e-16 57.6 0.2 2.3 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Pkinase PF00069.25 ETS72935.1 - 3.1e-58 197.2 0.0 4.3e-57 193.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS72935.1 - 2.4e-26 92.6 0.1 3.1e-20 72.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 ETS72935.1 - 3.9e-05 22.8 0.1 7e-05 21.9 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ETS72935.1 - 0.00041 20.4 0.2 0.033 14.1 0.3 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ETS72935.1 - 0.00069 19.0 0.0 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ETS72935.1 - 0.001 18.5 0.7 0.0015 17.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 ETS72935.1 - 0.079 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 ETS72935.1 - 0.94 9.0 4.3 0.69 9.5 0.1 2.2 2 0 0 2 2 2 0 RIO1 family SF3A2 PF16835.5 ETS72936.1 - 2.1e-38 130.6 0.1 3e-38 130.1 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 ETS72936.1 - 4e-06 27.0 0.9 7.1e-06 26.2 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 ETS72936.1 - 0.031 14.2 0.2 0.047 13.6 0.2 1.2 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 ETS72936.1 - 0.065 12.8 1.5 0.11 12.0 1.5 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like SLATT_fungal PF18142.1 ETS72938.1 - 2.1e-28 98.7 0.0 2.9e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Phage_holin_3_6 PF07332.11 ETS72938.1 - 0.081 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Spectrin PF00435.21 ETS72938.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Spectrin repeat AMP-binding PF00501.28 ETS72939.1 - 1e-78 264.8 0.0 1.6e-78 264.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 ETS72939.1 - 3.6e-77 259.4 0.0 7.5e-77 258.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ETS72939.1 - 2.8e-54 183.8 0.0 8.1e-54 182.2 0.0 1.9 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 ETS72939.1 - 3.9e-40 138.0 0.5 9.7e-40 136.6 0.5 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 ETS72939.1 - 8.3e-38 129.0 1.3 1.9e-37 127.9 1.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 ETS72939.1 - 2.2e-33 116.1 1.1 6.3e-33 114.6 1.1 1.7 1 1 0 1 1 1 1 Acyl transferase domain AMP-binding_C PF13193.6 ETS72939.1 - 2.4e-14 54.0 0.3 1.4e-13 51.6 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain KAsynt_C_assoc PF16197.5 ETS72939.1 - 5e-13 49.5 0.0 1.2e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thioesterase PF00975.20 ETS72939.1 - 3e-12 47.2 0.1 7.8e-11 42.5 0.0 2.9 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 ETS72939.1 - 4.1e-11 43.1 1.3 9.4e-08 32.3 0.2 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thiolase_N PF00108.23 ETS72939.1 - 3.4e-07 29.9 0.0 7.8e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short PF00106.25 ETS72939.1 - 1.3e-06 28.1 0.0 3.8e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Abhydrolase_6 PF12697.7 ETS72939.1 - 0.00011 22.9 0.6 0.00011 22.9 0.6 4.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ETS72939.1 - 0.0065 16.3 0.1 1.5 8.6 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Sucrose_synth PF00862.19 ETS72939.1 - 0.028 12.7 0.0 0.063 11.6 0.0 1.5 2 0 0 2 2 2 0 Sucrose synthase FAD_binding_5 PF00941.21 ETS72939.1 - 0.069 12.9 0.2 2.4 7.8 0.4 2.6 2 0 0 2 2 2 0 FAD binding domain in molybdopterin dehydrogenase Polysacc_synt_2 PF02719.15 ETS72939.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sugar_tr PF00083.24 ETS72940.1 - 3.5e-95 319.5 19.3 4.1e-95 319.3 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS72940.1 - 8e-22 77.6 21.8 8e-22 77.6 21.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS72940.1 - 1.7e-05 23.5 0.8 2.9e-05 22.7 0.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 ETS72940.1 - 0.0068 16.9 2.6 0.039 14.5 2.6 2.4 1 1 0 1 1 1 1 Phage holin family 2 DUF2530 PF10745.9 ETS72940.1 - 0.32 11.3 11.6 0.34 11.2 1.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Lyase_1 PF00206.20 ETS72941.1 - 1.4e-48 165.9 0.0 3.5e-48 164.6 0.0 1.5 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.9 ETS72941.1 - 7.1e-19 68.1 0.0 6.4e-18 65.1 0.0 2.5 2 1 1 3 3 3 1 Adenylosuccinate lyase C-terminus Fungal_trans PF04082.18 ETS72942.1 - 3.4e-22 78.8 0.9 5.1e-22 78.2 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS72942.1 - 1.1e-08 35.1 9.0 2e-08 34.2 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_92N PF17678.1 ETS72943.1 - 4.5e-63 213.3 1.4 5.9e-63 212.9 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Glyco_hydro_92 PF07971.12 ETS72943.1 - 3.4e-14 52.6 0.1 4.7e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92 PF07971.12 ETS72944.1 - 4.4e-89 299.5 7.0 5.4e-89 299.2 7.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92 PF07971.12 ETS72945.1 - 4e-05 22.7 0.0 4.5e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Poly_export PF02563.16 ETS72945.1 - 0.12 12.6 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein Mpv17_PMP22 PF04117.12 ETS72946.1 - 1.2e-21 76.7 0.2 2.7e-21 75.5 0.2 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family PGK PF00162.19 ETS72947.1 - 3.3e-152 506.8 0.9 3.8e-152 506.6 0.9 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 ETS72947.1 - 0.00014 21.8 0.2 0.022 14.8 0.0 3.1 3 1 1 4 4 4 1 PA domain DSS1_SEM1 PF05160.13 ETS72948.1 - 2.7e-22 78.6 14.0 4.7e-22 77.8 14.0 1.4 1 0 0 1 1 1 1 DSS1/SEM1 family DUF3808 PF10300.9 ETS72949.1 - 5.3e-124 414.6 0.0 6.4e-124 414.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_10 PF13374.6 ETS72949.1 - 0.0031 17.3 0.1 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 ETS72949.1 - 0.0031 17.5 1.1 0.012 15.7 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ETS72949.1 - 0.0057 16.9 0.1 0.022 15.0 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 ETS72949.1 - 0.016 15.7 5.1 0.17 12.4 0.2 4.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 ETS72949.1 - 0.074 13.7 0.1 0.6 10.9 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 ETS72949.1 - 0.16 12.9 5.4 0.22 12.5 0.3 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 ETS72949.1 - 0.39 10.6 2.6 0.52 10.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 ETS72949.1 - 0.45 10.9 0.1 0.45 10.9 0.1 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat CAP_N PF01213.19 ETS72950.1 - 2.3e-44 152.2 0.0 2.6e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal SKA2 PF16740.5 ETS72950.1 - 0.013 15.3 0.9 0.074 12.8 0.1 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF3237 PF11578.8 ETS72951.1 - 3.8e-34 117.7 0.0 4.2e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) MFS_1 PF07690.16 ETS72952.1 - 4.4e-37 127.8 20.0 4.4e-37 127.8 20.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS72952.1 - 4.8e-06 25.7 37.6 0.00015 20.8 37.7 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.18 ETS72953.1 - 1e-29 103.4 3.3 1.5e-29 102.9 3.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.22 ETS72954.1 - 2e-114 382.7 0.1 2.4e-114 382.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RPE65 PF03055.15 ETS72955.1 - 2.7e-107 359.9 0.0 3e-107 359.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Zn_ribbon_2 PF12674.7 ETS72955.1 - 0.13 12.9 0.0 0.25 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative zinc ribbon domain DUF2854 PF11016.8 ETS72956.1 - 0.091 12.7 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) Aldo_ket_red PF00248.21 ETS72957.1 - 9.7e-35 120.2 0.0 7.6e-31 107.4 0.0 3.0 1 1 0 1 1 1 1 Aldo/keto reductase family Sacchrp_dh_NADP PF03435.18 ETS72957.1 - 0.015 15.5 0.0 0.73 10.1 0.0 2.5 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain HIT PF01230.23 ETS72958.1 - 2.8e-16 60.0 0.0 4e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 ETS72958.1 - 4.6e-06 27.1 0.0 7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 ETS72958.1 - 0.0018 18.2 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DNA_RNApol_7kD PF03604.13 ETS72959.1 - 8.3e-15 54.2 7.9 1.1e-14 53.8 7.9 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 ETS72959.1 - 0.00072 19.6 0.2 0.00087 19.3 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 ETS72959.1 - 0.035 14.1 0.8 0.05 13.6 0.8 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-ISL3 PF14690.6 ETS72959.1 - 0.1 13.3 0.8 0.1 13.3 0.8 2.0 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf_UBZ PF18439.1 ETS72959.1 - 0.44 10.2 2.9 1.9 8.1 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger TF_Zn_Ribbon PF08271.12 ETS72959.1 - 2.1 7.9 7.9 9 5.9 7.9 1.9 1 1 0 1 1 1 0 TFIIB zinc-binding ATP_bind_1 PF03029.17 ETS72960.1 - 8.7e-72 241.8 0.0 1.4e-71 241.1 0.0 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 ETS72960.1 - 4.2e-05 23.4 0.0 8.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 ETS72960.1 - 9.1e-05 21.6 0.1 0.078 11.9 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 ETS72960.1 - 0.00017 21.2 0.0 0.015 14.9 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 ETS72960.1 - 0.0011 19.2 0.0 0.0034 17.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 ETS72960.1 - 0.0019 18.2 0.0 0.03 14.4 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 ETS72960.1 - 0.0022 18.2 0.0 2 8.6 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 ETS72960.1 - 0.0033 16.7 0.2 0.011 15.0 0.1 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 ETS72960.1 - 0.0043 17.5 0.0 0.0085 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 ETS72960.1 - 0.0051 17.3 0.0 1.3 9.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 ETS72960.1 - 0.0055 16.5 0.0 0.024 14.4 0.0 2.0 3 0 0 3 3 3 1 Phosphoribulokinase / Uridine kinase family FeoB_N PF02421.18 ETS72960.1 - 0.0067 16.0 0.1 0.2 11.2 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B NACHT PF05729.12 ETS72960.1 - 0.0072 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 ETS72960.1 - 0.0075 16.4 0.4 0.021 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ETS72960.1 - 0.016 15.0 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ETS72960.1 - 0.018 14.3 0.6 0.054 12.8 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Arf PF00025.21 ETS72960.1 - 0.025 14.0 0.0 0.97 8.9 0.0 2.9 3 0 0 3 3 3 0 ADP-ribosylation factor family SRP54 PF00448.22 ETS72960.1 - 0.026 14.2 0.0 0.066 12.8 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain G-alpha PF00503.20 ETS72960.1 - 0.027 13.6 0.0 0.29 10.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 ETS72960.1 - 0.037 13.9 0.0 16 5.4 0.0 3.3 4 0 0 4 4 4 0 RsgA GTPase Thymidylate_kin PF02223.17 ETS72960.1 - 0.069 12.8 0.6 0.87 9.2 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_7 PF12775.7 ETS72960.1 - 0.085 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region GrpE PF01025.19 ETS72960.1 - 0.11 12.1 4.4 7 6.3 0.0 2.2 1 1 1 2 2 2 0 GrpE PduV-EutP PF10662.9 ETS72960.1 - 0.13 12.0 0.0 0.92 9.2 0.0 2.3 3 1 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 ETS72960.1 - 0.15 11.6 0.1 0.66 9.5 0.0 1.9 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 ETS72960.1 - 0.31 11.6 0.0 0.31 11.6 0.0 2.6 3 1 1 4 4 2 0 AAA domain DUF1793 PF08760.11 ETS72961.1 - 0.037 14.5 0.0 0.1 13.0 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1793) CHAD PF05235.14 ETS72961.1 - 0.35 10.8 3.5 0.26 11.2 0.6 2.2 2 1 0 2 2 2 0 CHAD domain BTB PF00651.31 ETS72962.1 - 6.7e-08 32.7 0.0 1.6e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 ETS72962.1 - 0.0095 16.1 0.0 0.053 13.7 0.0 2.1 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Peptidase_S24 PF00717.23 ETS72964.1 - 9.7e-07 28.7 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like CwfJ_C_1 PF04677.15 ETS72965.1 - 9.9e-31 106.2 0.0 1.6e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 ETS72965.1 - 2e-27 95.9 0.2 7e-27 94.2 0.2 2.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 AlbA_2 PF04326.14 ETS72965.1 - 0.065 13.6 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative DNA-binding domain TFIIB PF00382.19 ETS72966.1 - 1.8e-29 101.6 0.0 5.1e-15 55.3 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 ETS72966.1 - 6e-22 77.9 0.3 6e-22 77.9 0.3 3.9 4 0 0 4 4 4 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 ETS72966.1 - 0.0022 17.8 0.2 1.4 8.6 0.0 2.4 1 1 1 2 2 2 2 Cyclin, N-terminal domain RNA_pol_3_Rpc31 PF11705.8 ETS72966.1 - 0.014 15.6 11.6 0.014 15.6 11.6 2.6 2 1 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Bac_rhamnosid6H PF17389.2 ETS72967.1 - 6.9e-08 32.1 0.1 1.5e-06 27.7 0.0 2.8 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 ETS72967.1 - 2.1e-06 27.4 0.0 5.5e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Glyco_hydro_36 PF17167.4 ETS72967.1 - 0.035 12.8 0.0 0.057 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Nucleos_tra2_C PF07662.13 ETS72968.1 - 1.2e-70 237.5 2.5 1.2e-70 237.5 2.5 2.3 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ETS72968.1 - 1.6e-23 83.1 4.9 1.6e-23 83.1 4.9 3.6 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 ETS72968.1 - 4.4 7.6 22.7 0.051 13.9 5.7 4.1 3 1 0 3 3 3 0 Nucleoside recognition TauD PF02668.16 ETS72969.1 - 7.3e-46 157.1 0.3 1e-45 156.6 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DAG1 PF05454.11 ETS72969.1 - 0.028 13.8 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) UQ_con PF00179.26 ETS72970.1 - 8.1e-44 148.7 0.0 9.2e-44 148.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ETS72970.1 - 3.8e-05 23.4 0.0 4.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ETS72970.1 - 0.0039 17.5 0.0 0.0062 16.8 0.0 1.4 1 1 0 1 1 1 1 RWD domain RabGAP-TBC PF00566.18 ETS72971.1 - 3.5e-35 121.6 0.1 9.4e-31 107.1 0.3 3.1 2 1 0 2 2 2 2 Rab-GTPase-TBC domain eIF3g PF12353.8 ETS72972.1 - 0.36 11.2 5.6 0.18 12.2 3.3 1.7 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Binary_toxB PF03495.14 ETS72973.1 - 0.052 13.7 0.2 0.18 12.0 0.2 2.0 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain DEAD PF00270.29 ETS72974.1 - 9.9e-48 162.2 0.0 1.6e-47 161.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS72974.1 - 1.3e-30 106.0 0.6 1.7e-29 102.4 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS72974.1 - 1.5e-07 31.6 0.0 3.9e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ORC6 PF05460.13 ETS72974.1 - 0.12 11.6 6.3 0.18 11.0 6.3 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Nop14 PF04147.12 ETS72974.1 - 5.8 5.0 13.1 8.3 4.5 13.1 1.1 1 0 0 1 1 1 0 Nop14-like family Brix PF04427.18 ETS72975.1 - 2.1e-48 165.0 0.0 3.1e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF2681 PF10883.8 ETS72975.1 - 0.019 15.4 5.2 0.043 14.2 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) PBP_sp32 PF07222.12 ETS72975.1 - 2.3 7.6 8.2 12 5.3 9.0 1.8 2 0 0 2 2 2 0 Proacrosin binding protein sp32 MFS_5 PF05631.14 ETS72976.1 - 1.7e-47 162.1 2.1 1.7e-47 162.1 2.1 1.5 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 ETS72976.1 - 4.3e-19 68.7 22.7 1.9e-18 66.5 17.2 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS72976.1 - 3.6e-06 26.1 0.0 3.6e-06 26.1 0.0 3.1 2 2 0 3 3 3 1 MFS_1 like family TM140 PF14985.6 ETS72976.1 - 0.47 10.0 8.7 0.66 9.5 0.4 2.7 1 1 0 2 2 2 0 TM140 protein family HsbA PF12296.8 ETS72977.1 - 5.2e-25 88.2 10.4 8.3e-25 87.5 10.4 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A FA_hydroxylase PF04116.13 ETS72978.1 - 1.6e-13 51.1 3.6 1.6e-13 51.1 3.6 2.3 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Abhydrolase_1 PF00561.20 ETS72979.1 - 1.8e-09 37.6 0.0 7.5e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS72979.1 - 3.9e-07 30.9 4.9 3.9e-07 30.9 4.9 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS72979.1 - 1.2e-05 24.7 0.0 0.0014 18.0 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 GST_N_3 PF13417.6 ETS72980.1 - 5.7e-06 26.7 0.0 1.4e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS72980.1 - 1.6e-05 24.8 1.3 3e-05 23.9 0.8 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ETS72980.1 - 0.014 15.7 0.0 0.033 14.5 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain CD34_antigen PF06365.12 ETS72981.1 - 0.00073 19.2 0.0 0.00081 19.0 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family Protocadherin PF08374.11 ETS72981.1 - 0.0016 18.4 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Protocadherin Syndecan PF01034.20 ETS72981.1 - 0.004 17.0 0.0 0.0068 16.3 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain LapA_dom PF06305.11 ETS72981.1 - 0.0056 16.5 0.0 0.0093 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain TMEM154 PF15102.6 ETS72981.1 - 0.007 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family ECSCR PF15820.5 ETS72981.1 - 0.0091 15.8 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator EphA2_TM PF14575.6 ETS72981.1 - 0.014 16.3 0.0 0.019 15.8 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 ETS72981.1 - 0.017 14.9 0.3 0.028 14.2 0.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF3084 PF11283.8 ETS72981.1 - 0.028 14.4 0.5 0.047 13.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3084) Glycophorin_A PF01102.18 ETS72981.1 - 0.042 14.1 0.4 0.082 13.2 0.4 1.4 1 1 0 1 1 1 0 Glycophorin A Herpes_gE PF02480.16 ETS72981.1 - 0.045 12.5 0.0 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E FAM176 PF14851.6 ETS72981.1 - 0.049 13.3 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 FAM176 family DUF5305 PF17231.2 ETS72981.1 - 0.056 12.8 0.0 0.1 12.0 0.0 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF3377 PF11857.8 ETS72981.1 - 0.09 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) TMEM52 PF14979.6 ETS72981.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane 52 FixH PF05751.11 ETS72982.1 - 0.044 13.8 2.7 1.6 8.7 0.1 2.2 2 0 0 2 2 2 0 FixH PRIMA1 PF16101.5 ETS72982.1 - 0.045 13.8 2.9 0.076 13.1 2.9 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Prominin PF05478.11 ETS72982.1 - 0.16 9.9 0.1 0.21 9.5 0.1 1.1 1 0 0 1 1 1 0 Prominin Pex14_N PF04695.13 ETS72982.1 - 0.19 12.4 8.2 0.29 11.8 8.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ycf9 PF01737.17 ETS72982.1 - 2.7 7.9 8.0 3.5 7.6 0.5 2.8 2 0 0 2 2 2 0 YCF9 Amidoligase_2 PF12224.8 ETS72983.1 - 2.5e-09 37.2 0.4 1.1e-05 25.3 0.1 2.8 2 1 0 2 2 2 2 Putative amidoligase enzyme Zn_clus PF00172.18 ETS72984.1 - 3.5e-08 33.4 10.9 5.6e-08 32.8 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain JAB PF01398.21 ETS72986.1 - 1.4e-08 34.7 0.1 7.9e-07 29.1 0.1 2.5 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease AdoHcyase PF05221.17 ETS72987.1 - 3.5e-130 433.5 0.0 1e-74 251.4 0.4 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 ETS72987.1 - 2.5e-83 278.0 2.4 4.3e-83 277.2 2.4 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 ETS72987.1 - 1.7e-06 27.5 0.2 4.4e-06 26.2 0.2 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ETS72987.1 - 0.025 14.2 0.5 0.049 13.2 0.5 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 ETS72987.1 - 0.057 13.1 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Urocanase PF01175.18 ETS72987.1 - 0.17 11.5 1.1 0.32 10.6 1.1 1.4 1 0 0 1 1 1 0 Urocanase Rossmann-like domain 2-Hacid_dh_C PF02826.19 ETS72988.1 - 5e-55 185.6 0.0 6.6e-55 185.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS72988.1 - 2.3e-18 66.1 0.0 2.7e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ETS72988.1 - 1.2e-05 25.6 0.0 3.9e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sugar_tr PF00083.24 ETS72989.1 - 6.1e-82 275.9 27.8 7.4e-82 275.6 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS72989.1 - 4e-35 121.4 52.8 6.1e-34 117.5 28.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS72989.1 - 3.1e-06 26.0 23.5 5.4e-05 21.9 8.9 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 ETS72989.1 - 0.0012 17.3 2.4 0.0012 17.3 2.4 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 ETS72989.1 - 0.002 16.6 5.3 0.002 16.6 5.3 3.0 2 1 0 2 2 2 1 Transmembrane secretion effector Phage_holin_3_2 PF04550.12 ETS72989.1 - 0.5 10.9 4.3 0.26 11.8 0.7 2.4 2 1 0 2 2 2 0 Phage holin family 2 Mito_carr PF00153.27 ETS72990.1 - 2.9e-43 145.7 4.5 5.3e-19 67.9 0.2 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Rod-binding PF10135.9 ETS72990.1 - 0.087 13.4 0.2 0.087 13.4 0.2 2.0 2 0 0 2 2 2 0 Rod binding protein ChAPs PF09295.10 ETS72991.1 - 1.4e-150 501.7 0.0 2e-150 501.2 0.0 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 ETS72991.1 - 6e-07 29.8 0.3 0.077 13.8 0.1 4.6 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 ETS72991.1 - 8e-07 28.8 0.0 0.0048 17.0 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 ETS72991.1 - 7.1e-06 25.7 1.3 0.016 15.3 0.4 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 ETS72991.1 - 9e-05 22.2 0.4 0.13 12.3 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ETS72991.1 - 0.00099 18.8 0.1 0.37 10.7 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ETS72991.1 - 0.022 15.0 1.7 15 6.0 0.4 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 ETS72991.1 - 0.024 14.8 0.1 1 9.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 ETS72991.1 - 0.035 14.6 0.1 5.1 7.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ETS72991.1 - 0.11 13.2 0.1 28 5.6 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DHDPS PF00701.22 ETS72991.1 - 0.11 11.2 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family TPR_14 PF13428.6 ETS72992.1 - 0.0028 18.3 4.4 3.4 8.7 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 ETS72992.1 - 0.017 15.4 0.2 49 4.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 ETS72992.1 - 0.019 15.1 1.3 0.077 13.1 1.3 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 ETS72992.1 - 0.094 13.2 5.1 13 6.4 0.3 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Sperm_Ag_HE2 PF05324.13 ETS72992.1 - 0.21 12.1 1.3 29 5.2 0.0 2.7 2 0 0 2 2 2 0 Sperm antigen HE2 TPR_16 PF13432.6 ETS72992.1 - 0.29 11.8 7.6 7.2 7.4 0.7 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Fungal_trans PF04082.18 ETS72993.1 - 1.7e-11 43.6 0.3 4.2e-11 42.4 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain GST_N_2 PF13409.6 ETS72994.1 - 3.8e-11 43.1 0.0 7.6e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ETS72994.1 - 1.2e-09 38.3 0.0 2.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ETS72994.1 - 8.2e-09 35.6 0.0 1.9e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ETS72994.1 - 8.5e-09 35.5 0.0 1.7e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ETS72994.1 - 5.4e-08 33.1 0.0 8.9e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS72994.1 - 0.00062 19.7 0.0 0.0012 18.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 ETS72994.1 - 0.081 13.2 0.0 0.26 11.6 0.0 1.8 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein p450 PF00067.22 ETS72995.1 - 2e-58 198.2 0.0 2.6e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Dioxygenase_C PF00775.21 ETS72996.1 - 3.2e-09 36.5 0.0 6.1e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase YsaB PF13983.6 ETS72996.1 - 0.061 13.6 0.0 0.47 10.8 0.0 2.2 2 0 0 2 2 2 0 YsaB-like lipoprotein AA_permease PF00324.21 ETS72997.1 - 3.1e-117 392.1 43.4 3.8e-117 391.8 43.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS72997.1 - 7.9e-35 120.5 49.1 1.1e-34 120.1 49.1 1.1 1 0 0 1 1 1 1 Amino acid permease NAD_binding_2 PF03446.15 ETS72998.1 - 2.5e-27 96.0 0.0 3.5e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ETS72998.1 - 5.3e-23 81.6 0.0 9.1e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase UDPG_MGDP_dh PF00984.19 ETS72998.1 - 0.015 15.5 0.1 0.036 14.3 0.1 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 ETS72998.1 - 0.12 12.0 0.0 0.88 9.1 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aldedh PF00171.22 ETS72999.1 - 6.3e-175 582.1 0.0 7.1e-175 581.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1993 PF09351.10 ETS73000.1 - 2.2e-49 167.7 0.0 2.4e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) E1-E2_ATPase PF00122.20 ETS73001.1 - 1.2e-36 125.9 15.1 2.4e-29 102.2 0.0 3.8 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 ETS73001.1 - 5.4e-28 97.9 3.2 5.4e-28 97.9 3.2 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ETS73001.1 - 3.8e-19 69.8 1.9 3.7e-16 60.1 0.2 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ETS73001.1 - 1.3e-14 53.6 0.1 3.5e-14 52.2 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ETS73001.1 - 2.4e-13 50.0 0.0 4.6e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ETS73001.1 - 1.2e-07 31.8 1.3 5.1e-06 26.4 0.7 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ETS73001.1 - 0.039 14.4 0.1 0.12 12.8 0.1 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Amidohydro_3 PF07969.11 ETS73002.1 - 1.5e-68 232.4 2.3 1.8e-68 232.1 2.3 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ETS73002.1 - 7e-08 32.2 0.5 0.001 18.5 0.2 2.8 2 1 0 2 2 2 2 Amidohydrolase family Lactamase_B_2 PF12706.7 ETS73003.1 - 3.2e-14 52.9 0.1 7.4e-14 51.7 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ETS73003.1 - 3.7e-11 43.2 0.0 5.2e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SprT-like PF10263.9 ETS73005.1 - 0.00093 19.0 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 SprT-like family DA1-like PF12315.8 ETS73005.1 - 0.0016 17.9 0.3 0.0025 17.3 0.3 1.2 1 0 0 1 1 1 1 Protein DA1 Peptidase_M91 PF14891.6 ETS73005.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Effector protein DUF3060 PF11259.8 ETS73006.1 - 0.03 14.0 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3060) PET10 PF17316.2 ETS73006.1 - 0.14 11.6 1.2 0.17 11.4 1.2 1.0 1 0 0 1 1 1 0 Petite colonies protein 10 Glyco_hydro_30 PF02055.16 ETS73007.1 - 4.9e-36 124.4 5.1 6.6e-36 124.0 5.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 ETS73007.1 - 8.8e-09 35.5 2.6 6.4e-08 32.7 0.9 2.7 1 1 1 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 ETS73007.1 - 2.9e-05 23.4 1.4 4.6e-05 22.8 1.4 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 ETS73007.1 - 0.0019 17.8 0.1 0.0034 17.1 0.1 1.3 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 BTB PF00651.31 ETS73008.1 - 0.029 14.6 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain UQ_con PF00179.26 ETS73009.1 - 1.6e-20 73.2 0.0 2.2e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.23 ETS73010.1 - 1.8e-42 146.0 0.2 2.3e-42 145.6 0.2 1.1 1 0 0 1 1 1 1 Surface antigen MFS_1 PF07690.16 ETS73011.1 - 4.5e-22 78.5 34.6 4.5e-22 78.5 34.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS73011.1 - 8.5e-12 44.7 3.7 8.5e-12 44.7 3.7 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter IATP PF04568.12 ETS73012.1 - 0.03 14.7 4.5 0.035 14.5 3.4 1.7 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP adh_short PF00106.25 ETS73013.1 - 8e-30 103.8 0.1 1.3e-29 103.1 0.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS73013.1 - 3.5e-21 75.8 0.1 4.7e-21 75.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ETS73013.1 - 0.075 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 ETS73013.1 - 0.11 12.2 1.0 0.22 11.3 0.2 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.10 ETS73013.1 - 0.13 12.1 1.1 0.82 9.6 1.1 2.3 1 1 0 1 1 1 0 KR domain ADH_N PF08240.12 ETS73015.1 - 1.1e-07 31.7 0.3 6.3e-07 29.3 0.0 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS73015.1 - 0.00011 22.1 1.3 0.00011 22.1 1.3 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 ETS73016.1 - 3e-29 101.9 0.0 2.7e-20 72.7 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS73016.1 - 2.7e-18 66.4 0.0 1.1e-11 44.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS73016.1 - 1.3e-09 38.2 0.1 2.1e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 KR domain FMO-like PF00743.19 ETS73018.1 - 1.6e-26 92.9 0.0 1.8e-12 46.5 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ETS73018.1 - 7.4e-10 38.6 0.0 2.5e-06 27.0 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS73018.1 - 4.8e-07 29.3 0.0 4.3e-06 26.2 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS73018.1 - 1.1e-06 28.0 0.4 0.27 10.3 0.0 3.7 4 0 0 4 4 4 3 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ETS73018.1 - 3.2e-05 24.1 0.0 0.0001 22.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS73018.1 - 0.00038 20.5 0.2 0.013 15.5 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Glu_dehyd_C PF16912.5 ETS73018.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Thi4 PF01946.17 ETS73018.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 ETS73018.1 - 0.2 10.3 0.2 0.33 9.6 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.16 ETS73020.1 - 6.5e-24 84.5 54.2 1.1e-20 73.9 40.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.19 ETS73021.1 - 2.8e-58 197.8 0.0 4e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ETS73021.1 - 3e-05 22.9 0.2 0.00015 20.6 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 ETS73021.1 - 5.7e-05 22.5 0.1 0.0068 15.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS73021.1 - 0.00024 20.3 0.1 0.00057 19.1 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ETS73021.1 - 0.00028 20.3 0.2 0.00046 19.7 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 ETS73021.1 - 0.00069 19.3 0.4 0.0032 17.1 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ETS73021.1 - 0.0024 16.8 0.0 0.0055 15.6 0.0 1.6 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 ETS73021.1 - 0.0031 16.8 0.1 0.0068 15.7 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS73021.1 - 0.0035 17.6 0.1 0.011 16.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ETS73021.1 - 0.0045 16.3 0.0 0.0095 15.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 ETS73021.1 - 0.011 14.9 0.4 0.048 12.7 0.2 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein T5orf172 PF10544.9 ETS73021.1 - 0.016 15.7 0.0 2.8 8.5 0.0 2.4 2 0 0 2 2 2 0 T5orf172 domain DIT1_PvcA PF05141.12 ETS73022.1 - 4.3e-94 315.1 0.0 5.5e-94 314.7 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 ETS73022.1 - 3.6e-20 72.9 0.0 1.1e-19 71.3 0.0 1.8 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3891 PF13030.6 ETS73022.1 - 0.18 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) Epimerase PF01370.21 ETS73023.1 - 5.6e-10 39.1 0.0 8.2e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS73023.1 - 6.6e-06 26.1 0.0 9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ETS73023.1 - 0.0022 17.5 0.0 0.093 12.1 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ETS73023.1 - 0.0022 17.6 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 ETS73023.1 - 0.0064 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 ETS73023.1 - 0.033 13.3 0.0 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Fungal_trans PF04082.18 ETS73024.1 - 1.8e-25 89.5 0.0 2.6e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS73024.1 - 4.3e-08 33.1 6.7 7e-08 32.5 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SSV1_ORF_D-335 PF07935.11 ETS73024.1 - 0.074 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 ORF D-335-like protein Amidohydro_2 PF04909.14 ETS73025.1 - 2.8e-28 99.6 0.0 3.4e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase p450 PF00067.22 ETS73026.1 - 1.9e-44 152.2 0.0 2.3e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FMO-like PF00743.19 ETS73027.1 - 9.9e-11 40.7 0.0 1.5e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ETS73027.1 - 9.4e-09 34.9 0.1 7.8e-06 25.3 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ETS73027.1 - 4e-06 26.3 0.0 1.7e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS73027.1 - 0.0002 21.5 0.0 0.00045 20.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS73027.1 - 0.0059 15.9 0.0 0.38 9.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS73027.1 - 0.011 16.3 0.0 7.1 7.3 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ETS73027.1 - 0.072 13.5 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 ETS73027.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 ETS73027.1 - 0.13 12.2 0.8 0.89 9.5 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding adh_short PF00106.25 ETS73028.1 - 4.4e-33 114.4 0.0 7.3e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS73028.1 - 5.3e-18 65.4 0.0 7.8e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS73028.1 - 7e-09 35.8 0.0 3.9e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS73028.1 - 0.00049 19.6 0.0 0.00065 19.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS73028.1 - 0.0058 15.7 0.0 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TEX13 PF15186.6 ETS73028.1 - 0.11 12.1 0.0 12 5.6 0.0 2.1 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family PCNA_N PF00705.18 ETS73028.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain Polysacc_synt_2 PF02719.15 ETS73028.1 - 0.16 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Abhydrolase_3 PF07859.13 ETS73029.1 - 2.2e-23 83.2 0.0 2.9e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS73029.1 - 2.4e-12 46.4 0.0 3.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 ETS73029.1 - 0.018 14.8 0.0 0.038 13.8 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Glyco_hydro_12 PF01670.16 ETS73030.1 - 4e-23 82.5 4.0 4e-23 82.5 4.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 Glyco_hydro_3_C PF01915.22 ETS73032.1 - 1.6e-54 185.0 0.0 2.6e-54 184.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS73032.1 - 1.3e-38 133.2 0.0 2e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS73032.1 - 2.6e-19 69.1 0.0 5.3e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 ETS73032.1 - 5.5e-06 26.2 0.0 9.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Tnp_DNA_bind PF14706.6 ETS73032.1 - 0.069 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Transposase DNA-binding Sugar_tr PF00083.24 ETS73033.1 - 7.4e-76 255.8 28.3 8.5e-76 255.6 28.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS73033.1 - 5e-17 61.9 39.3 1.2e-16 60.6 32.5 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Fungal_trans PF04082.18 ETS73034.1 - 0.029 13.4 2.4 1.3 8.0 2.4 3.0 1 1 0 1 1 1 0 Fungal specific transcription factor domain Glyco_hydro_61 PF03443.14 ETS73035.1 - 1.4e-60 204.8 0.9 1.7e-60 204.5 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ETS73035.1 - 0.00062 20.5 0.2 0.0017 19.0 0.1 1.5 1 1 1 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading TyrRSs_C PF16714.5 ETS73035.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain GCIP PF13324.6 ETS73036.1 - 1.7e-27 96.7 0.0 5e-27 95.1 0.0 1.7 1 1 1 2 2 2 1 Grap2 and cyclin-D-interacting DUF3736 PF12540.8 ETS73036.1 - 0.0031 17.6 0.3 0.017 15.2 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3736) Fungal_trans_2 PF11951.8 ETS73036.1 - 0.016 14.0 0.2 0.037 12.9 0.0 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain Pes-10 PF07149.11 ETS73036.1 - 0.033 13.2 2.8 0.048 12.7 2.8 1.2 1 0 0 1 1 1 0 Pes-10 DUF4611 PF15387.6 ETS73036.1 - 0.088 13.0 3.4 0.26 11.6 3.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) SPOC PF07744.13 ETS73037.1 - 3.1e-22 79.1 0.0 5.3e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 ETS73037.1 - 3.6e-15 56.4 2.1 9.9e-15 55.0 2.1 1.8 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 ETS73037.1 - 6.5e-09 35.6 8.2 1.2e-08 34.7 8.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-XS PF03470.14 ETS73037.1 - 0.035 14.4 0.6 0.15 12.3 0.6 2.1 1 0 0 1 1 1 0 XS zinc finger domain Proteasome PF00227.26 ETS73038.1 - 2.6e-60 203.2 0.1 3.2e-60 202.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ETS73038.1 - 2.7e-13 49.3 0.1 8.7e-13 47.7 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 ETS73038.1 - 0.015 15.4 0.4 0.04 14.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 ETS73038.1 - 0.024 14.2 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit NTP_transferase PF00483.23 ETS73039.1 - 1.7e-30 106.4 0.0 2.2e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 ETS73039.1 - 5e-10 38.7 5.2 7.5e-07 28.6 0.0 3.5 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ETS73039.1 - 5.9e-07 30.0 0.0 8.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 ETS73039.1 - 0.017 14.9 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.6 ETS73039.1 - 0.026 14.2 0.1 2.4 8.0 0.0 3.4 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 ETS73039.1 - 0.048 12.6 0.0 1.5 7.7 0.0 2.1 2 0 0 2 2 2 0 L-fucokinase Peptidase_M54 PF07998.11 ETS73040.1 - 6.3e-10 39.4 0.2 1.1e-09 38.6 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M54 Peptidase_M10 PF00413.24 ETS73040.1 - 0.0006 19.7 0.0 0.00095 19.0 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.8 ETS73040.1 - 0.0064 16.1 0.1 0.017 14.7 0.1 1.6 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Reprolysin PF01421.19 ETS73040.1 - 0.03 14.2 0.5 0.051 13.5 0.5 1.4 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease DUF4953 PF16313.5 ETS73040.1 - 0.032 13.5 0.2 0.055 12.7 0.2 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_5 PF13688.6 ETS73040.1 - 0.072 13.2 1.0 0.15 12.2 1.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 ETS73040.1 - 0.073 13.6 0.4 0.15 12.5 0.4 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 ETS73040.1 - 0.1 11.2 1.2 0.17 10.5 1.2 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_4 PF13583.6 ETS73040.1 - 0.13 11.9 0.5 0.21 11.2 0.5 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 ETS73040.1 - 0.39 9.6 1.0 0.63 8.9 1.0 1.3 1 0 0 1 1 1 0 Peptidase M66 FAA_hydrolase PF01557.18 ETS73041.1 - 1.3e-57 195.0 0.0 1.7e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 ETS73041.1 - 1.6e-33 115.1 0.0 3.6e-33 113.9 0.0 1.6 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Fungal_trans PF04082.18 ETS73042.1 - 2.5e-14 53.0 0.2 1.6e-13 50.3 0.2 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS73042.1 - 1.8e-07 31.2 12.5 3.4e-07 30.3 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HalX PF08663.10 ETS73042.1 - 0.097 13.0 0.1 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 HalX domain LPP PF04728.13 ETS73042.1 - 0.34 11.3 1.0 3.7 8.0 0.1 2.9 3 0 0 3 3 3 0 Lipoprotein leucine-zipper COG5 PF10392.9 ETS73042.1 - 1.9 8.7 5.3 22 5.2 0.1 3.5 3 1 1 4 4 4 0 Golgi transport complex subunit 5 Arylesterase PF01731.20 ETS73043.1 - 0.044 14.0 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 Arylesterase Methyltransf_12 PF08242.12 ETS73045.1 - 7.4e-06 26.6 0.0 1.4e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS73045.1 - 2.9e-05 24.7 0.0 5.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS73045.1 - 0.00017 21.5 0.0 0.00042 20.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS73045.1 - 0.004 17.0 0.0 0.0072 16.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS73045.1 - 0.0045 16.5 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain ketoacyl-synt PF00109.26 ETS73046.1 - 1.1e-71 241.4 0.1 2.6e-71 240.2 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ETS73046.1 - 1.3e-48 165.3 0.0 4.8e-48 163.5 0.0 2.1 2 0 0 2 2 1 1 KR domain PS-DH PF14765.6 ETS73046.1 - 6.2e-46 157.0 0.0 1e-45 156.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ETS73046.1 - 2.2e-39 135.8 0.5 9.1e-39 133.8 0.2 2.1 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ETS73046.1 - 5.4e-38 129.6 0.2 1.9e-37 127.9 0.3 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ETS73046.1 - 1.3e-16 61.1 0.0 3.5e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS73046.1 - 3e-14 53.2 0.0 1.4e-13 51.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ETS73046.1 - 2.7e-13 50.4 0.1 5.6e-10 39.7 0.0 2.6 1 1 1 2 2 2 2 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 ETS73046.1 - 5.6e-12 46.2 0.0 2.3e-11 44.2 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS73046.1 - 5.2e-09 36.6 0.0 1.7e-08 35.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 ETS73046.1 - 1.6e-08 34.2 0.0 6.4e-08 32.3 0.0 2.0 2 1 0 2 2 2 1 short chain dehydrogenase Methyltransf_31 PF13847.6 ETS73046.1 - 4.2e-08 33.1 0.0 9.1e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS73046.1 - 6.7e-06 25.6 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 ETS73046.1 - 4.6e-05 22.9 0.1 0.00012 21.6 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 ETS73046.1 - 0.00023 21.5 0.1 0.00069 19.9 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAT PF16073.5 ETS73046.1 - 0.00025 20.9 0.1 0.0046 16.7 0.1 2.7 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_16 PF10294.9 ETS73046.1 - 0.0091 15.8 0.0 0.035 13.8 0.0 1.9 2 0 0 2 2 2 1 Lysine methyltransferase ACP_syn_III PF08545.10 ETS73046.1 - 0.013 15.3 0.2 0.038 13.8 0.2 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_24 PF13578.6 ETS73046.1 - 0.06 14.4 0.0 2.9 8.9 0.0 3.2 2 0 0 2 2 2 0 Methyltransferase domain Egh16-like PF11327.8 ETS73048.1 - 5.3e-30 105.2 12.8 7.2e-30 104.8 12.8 1.2 1 0 0 1 1 1 1 Egh16-like virulence factor ADH_zinc_N PF00107.26 ETS73049.1 - 6.9e-28 97.2 1.8 1.2e-27 96.4 1.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS73049.1 - 1.2e-26 92.8 1.6 2.1e-26 91.9 1.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ETS73049.1 - 1.2e-20 74.9 0.0 2.4e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ETS73049.1 - 0.0062 16.0 0.6 0.0098 15.4 0.6 1.4 1 0 0 1 1 1 1 short chain dehydrogenase ELFV_dehydrog PF00208.21 ETS73049.1 - 0.097 12.4 0.3 0.14 11.9 0.3 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PBP1_TM PF14812.6 ETS73050.1 - 0.12 12.8 2.9 0.21 12.0 2.9 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3395 PF11875.8 ETS73051.1 - 0.068 13.1 0.0 0.091 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) ABC2_membrane_2 PF12679.7 ETS73052.1 - 0.33 10.2 0.0 0.33 10.2 0.0 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF3659 PF12396.8 ETS73053.1 - 1.3e-16 60.2 8.0 5.8e-11 42.2 4.8 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) DUF3659 PF12396.8 ETS73054.1 - 4.1e-162 526.3 123.5 7.3e-23 80.3 1.0 12.2 11 1 0 11 11 11 9 Protein of unknown function (DUF3659) Apolipoprotein PF01442.18 ETS73054.1 - 2.8e-09 37.1 0.4 2.8e-09 37.1 0.4 3.2 3 1 0 3 3 3 1 Apolipoprotein A1/A4/E domain Phasin_2 PF09361.10 ETS73054.1 - 0.0016 18.7 1.1 0.94 9.8 0.2 3.3 1 1 2 3 3 3 1 Phasin protein DUF883 PF05957.13 ETS73054.1 - 0.01 16.4 8.2 3.1 8.5 0.2 4.6 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 ETS73054.1 - 0.046 13.8 6.7 3.2 7.8 0.1 4.3 3 1 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) GCV_T_C PF08669.11 ETS73054.1 - 0.14 12.1 8.0 1.9 8.4 0.0 5.3 6 0 0 6 6 6 0 Glycine cleavage T-protein C-terminal barrel domain ATP-synt_B PF00430.18 ETS73054.1 - 1.1 9.4 4.8 1 9.4 0.8 2.8 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) DUF948 PF06103.11 ETS73054.1 - 2.8 8.3 16.9 7.6 6.9 0.8 5.5 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) CBS PF00571.28 ETS73054.1 - 9.4 6.8 7.2 1e+02 3.5 0.1 5.1 4 0 0 4 4 4 0 CBS domain PGAP1 PF07819.13 ETS73055.1 - 5.8e-05 22.9 0.0 0.00018 21.3 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 ETS73055.1 - 0.005 16.4 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 ETS73055.1 - 0.0056 16.0 0.0 0.23 10.7 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS73055.1 - 0.0057 17.3 0.1 0.011 16.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorosome_CsmC PF11098.8 ETS73056.1 - 0.00068 19.6 3.2 0.00092 19.2 3.2 1.2 1 0 0 1 1 1 1 Chlorosome envelope protein C Collagen_mid PF15984.5 ETS73056.1 - 0.0011 18.8 14.9 0.0011 18.8 14.9 1.8 1 1 0 1 1 1 1 Bacterial collagen, middle region Acetyltransf_7 PF13508.7 ETS73057.1 - 0.003 18.0 0.0 0.0049 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS73057.1 - 0.013 15.7 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS73057.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain F-box PF00646.33 ETS73058.1 - 0.00013 21.7 0.0 0.00036 20.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ETS73058.1 - 0.00063 19.6 0.6 0.0014 18.5 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 ETS73058.1 - 0.041 13.9 2.5 0.082 12.9 1.7 2.0 2 1 0 2 2 2 0 F-box-like domain REV PF00424.18 ETS73058.1 - 0.16 12.0 2.0 8.1 6.5 0.1 2.4 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) CBM-like PF14683.6 ETS73060.1 - 8.7e-36 123.3 0.2 5.5e-35 120.7 0.1 2.3 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 ETS73060.1 - 1.7e-13 50.1 2.7 4.8e-13 48.7 2.7 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 ETS73060.1 - 7.9e-07 29.3 1.7 2.7e-06 27.5 1.7 2.0 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Cu_amine_oxid PF01179.20 ETS73061.1 - 9e-160 532.1 0.0 1.1e-159 531.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 ETS73061.1 - 3.1e-21 75.7 0.9 8.6e-21 74.2 0.1 2.1 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 ETS73061.1 - 2.2e-15 56.6 0.0 3.7e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain RdgC PF04381.12 ETS73061.1 - 0.18 11.1 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative exonuclease, RdgC p450 PF00067.22 ETS73062.1 - 9.6e-61 205.9 0.0 1.2e-60 205.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 ETS73063.1 - 2.5e-28 98.9 0.5 7.6e-27 94.0 0.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS73063.1 - 3.1e-21 76.0 0.7 5.3e-20 72.0 0.7 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS73063.1 - 9.2e-06 25.7 0.3 1.5e-05 25.0 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS73063.1 - 0.00015 21.3 0.6 0.00031 20.3 0.6 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS73063.1 - 0.078 12.9 0.5 0.16 11.9 0.5 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ETS73063.1 - 0.12 11.4 0.1 0.18 10.9 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HgmA PF04209.13 ETS73064.1 - 5.7e-193 641.4 0.3 6.6e-193 641.2 0.3 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAD_binding_3 PF01494.19 ETS73065.1 - 1.4e-15 57.4 0.0 2.7e-15 56.5 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS73065.1 - 0.0033 16.7 0.1 0.17 11.1 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase ApoLp-III PF07464.11 ETS73066.1 - 1.8e-05 24.9 2.2 4.3e-05 23.6 2.2 1.6 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) EspB PF05802.11 ETS73066.1 - 0.00013 22.0 3.6 0.00023 21.2 3.6 1.3 1 0 0 1 1 1 1 Enterobacterial EspB protein DUF3552 PF12072.8 ETS73066.1 - 0.00068 19.1 5.5 0.00068 19.1 5.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) Apolipoprotein PF01442.18 ETS73066.1 - 0.00087 19.2 0.2 0.0017 18.2 0.2 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 ETS73066.1 - 0.00093 19.2 0.5 0.0085 16.1 0.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 ETS73066.1 - 0.0012 19.2 1.4 0.12 12.8 1.4 2.8 2 1 0 2 2 2 1 Flagella accessory protein C (FlaC) DUF883 PF05957.13 ETS73066.1 - 0.0036 17.9 1.4 0.011 16.3 1.4 1.9 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Carbpep_Y_N PF05388.11 ETS73066.1 - 0.0039 17.7 2.5 0.013 16.1 2.0 2.0 1 1 1 2 2 2 1 Carboxypeptidase Y pro-peptide FIVAR PF07554.13 ETS73066.1 - 0.0064 17.2 1.2 0.013 16.2 1.2 1.5 1 0 0 1 1 1 1 FIVAR domain Syntaxin-6_N PF09177.11 ETS73066.1 - 0.0097 16.4 1.9 0.057 14.0 0.5 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal DUF4795 PF16043.5 ETS73066.1 - 0.01 15.4 1.4 0.02 14.5 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Sec8_exocyst PF04048.14 ETS73066.1 - 0.012 15.6 0.2 0.02 14.7 0.2 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Filament PF00038.21 ETS73066.1 - 0.017 14.7 0.9 0.75 9.3 0.0 2.1 2 0 0 2 2 2 0 Intermediate filament protein PIN_8 PF18476.1 ETS73066.1 - 0.02 14.8 0.9 0.032 14.1 0.9 1.2 1 0 0 1 1 1 0 PIN like domain VSG_B PF13206.6 ETS73066.1 - 0.02 14.2 1.0 0.031 13.5 1.0 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain LMP PF04778.12 ETS73066.1 - 0.021 14.8 0.9 0.033 14.1 0.9 1.3 1 0 0 1 1 1 0 LMP repeated region ApoO PF09769.9 ETS73066.1 - 0.021 14.8 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein O PqqD PF05402.12 ETS73066.1 - 0.023 15.0 1.8 0.066 13.5 0.2 2.2 1 1 1 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Phasin PF05597.11 ETS73066.1 - 0.023 14.7 4.4 0.023 14.7 4.4 2.0 2 1 0 2 2 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Histidinol_dh PF00815.20 ETS73066.1 - 0.028 13.4 1.4 0.039 13.0 1.4 1.1 1 0 0 1 1 1 0 Histidinol dehydrogenase YtxH PF12732.7 ETS73066.1 - 0.03 14.9 12.0 0.32 11.6 12.1 2.3 1 1 1 2 2 2 0 YtxH-like protein Sec5 PF15469.6 ETS73066.1 - 0.037 13.8 0.1 0.059 13.2 0.1 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 RIFIN PF02009.16 ETS73066.1 - 0.037 13.9 0.3 0.054 13.4 0.3 1.1 1 0 0 1 1 1 0 Rifin Prominin PF05478.11 ETS73066.1 - 0.041 11.9 0.1 0.062 11.3 0.1 1.3 1 0 0 1 1 1 0 Prominin IucA_IucC PF04183.12 ETS73066.1 - 0.056 13.0 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 IucA / IucC family Gp-FAR-1 PF05823.12 ETS73066.1 - 0.058 13.7 0.9 0.12 12.7 0.9 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF1451 PF07295.11 ETS73066.1 - 0.068 13.2 1.8 0.15 12.1 1.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain CdvA PF18822.1 ETS73066.1 - 0.074 12.9 2.9 0.18 11.6 2.9 1.7 1 1 0 1 1 1 0 CdvA-like coiled-coil domain DUF5610 PF18433.1 ETS73066.1 - 0.075 13.5 0.4 0.12 12.8 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5610) DUF2011 PF09428.10 ETS73066.1 - 0.075 13.3 0.1 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) LMBR1 PF04791.16 ETS73066.1 - 0.081 11.8 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein HSCB_C PF07743.13 ETS73066.1 - 0.081 13.4 6.2 1 9.9 3.9 2.5 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain YkyA PF10368.9 ETS73066.1 - 0.084 12.5 3.0 0.14 11.9 3.0 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Activator-TraM PF11657.8 ETS73066.1 - 0.093 12.6 3.3 0.15 11.9 3.3 1.2 1 0 0 1 1 1 0 Transcriptional activator TraM DUF2884 PF11101.8 ETS73066.1 - 0.094 12.2 1.3 0.17 11.4 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DUF4618 PF15397.6 ETS73066.1 - 0.13 11.7 2.3 1.1 8.6 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF948 PF06103.11 ETS73066.1 - 0.14 12.4 4.6 0.31 11.3 1.6 3.0 3 1 1 4 4 3 0 Bacterial protein of unknown function (DUF948) KfrA_N PF11740.8 ETS73066.1 - 0.15 12.8 2.9 0.2 12.3 0.6 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Fib_alpha PF08702.10 ETS73066.1 - 0.21 11.8 0.5 1.9 8.7 0.1 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HemY_N PF07219.13 ETS73066.1 - 0.25 11.6 0.7 0.49 10.6 0.1 1.8 2 0 0 2 2 1 0 HemY protein N-terminus Calpain_inhib PF00748.19 ETS73066.1 - 0.31 11.5 5.3 0.59 10.6 5.3 1.4 1 0 0 1 1 1 0 Calpain inhibitor PEP-utilisers_N PF05524.13 ETS73066.1 - 0.32 11.2 4.0 1.8 8.8 4.0 2.1 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF4375 PF14300.6 ETS73066.1 - 0.33 11.2 3.3 0.19 12.0 0.5 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4375) Perilipin PF03036.16 ETS73066.1 - 0.68 8.9 3.6 0.2 10.6 0.8 1.5 2 0 0 2 2 1 0 Perilipin family Prefoldin_2 PF01920.20 ETS73066.1 - 0.77 9.7 6.0 0.31 11.0 2.2 2.0 2 0 0 2 2 2 0 Prefoldin subunit BST2 PF16716.5 ETS73066.1 - 0.98 10.0 5.2 0.82 10.3 1.7 2.1 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 HIP1_clath_bdg PF16515.5 ETS73066.1 - 1.2 9.8 4.9 0.46 11.1 0.7 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prefoldin PF02996.17 ETS73066.1 - 1.2 9.0 5.4 1.2 9.0 3.7 1.8 2 0 0 2 2 2 0 Prefoldin subunit SseC PF04888.12 ETS73066.1 - 1.3 8.6 8.4 0.95 9.0 3.6 2.2 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family NRN1 PF15056.6 ETS73066.1 - 1.6 8.9 3.3 0.87 9.7 0.7 1.9 2 1 0 2 2 1 0 Neuritin protein family DUF2433 PF10360.9 ETS73066.1 - 2.1 8.4 6.9 8.6 6.5 1.4 2.9 2 1 1 3 3 2 0 Protein of unknown function (DUF2433) LEA_1 PF03760.15 ETS73066.1 - 2.6 8.7 10.4 5.8 7.6 10.3 1.6 1 1 0 1 1 1 0 Late embryogenesis abundant (LEA) group 1 Spc7 PF08317.11 ETS73066.1 - 2.9 6.7 6.8 0.55 9.1 1.9 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein FAM25 PF15825.5 ETS73066.1 - 3.5 8.0 13.9 8.3 6.8 4.4 2.3 1 1 1 2 2 2 0 FAM25 family ATP-synt_B PF00430.18 ETS73066.1 - 3.6 7.7 10.5 0.22 11.6 3.2 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) LPP PF04728.13 ETS73066.1 - 4.6 7.7 7.4 38 4.8 0.0 3.5 2 1 2 4 4 4 0 Lipoprotein leucine-zipper CsbD PF05532.12 ETS73066.1 - 5.4 7.0 14.0 23 5.0 8.1 3.0 2 1 0 2 2 1 0 CsbD-like Abhydrolase_6 PF12697.7 ETS73068.1 - 9.8e-13 49.2 0.7 1.3e-11 45.5 0.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS73068.1 - 7.5e-12 45.4 0.2 3.3e-10 40.0 0.0 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS73068.1 - 8e-08 31.8 0.0 2.9e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 ETS73068.1 - 8.3e-08 32.6 0.0 1.2e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 ETS73068.1 - 0.0075 16.1 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Palm_thioest PF02089.15 ETS73068.1 - 0.008 16.0 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase zf-SNAP50_C PF12251.8 ETS73068.1 - 0.033 13.9 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal MRP-L28 PF09812.9 ETS73068.1 - 0.037 14.2 1.7 0.057 13.6 1.7 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 AT_hook PF02178.19 ETS73069.1 - 0.0023 17.6 19.6 0.18 11.8 7.0 2.7 2 0 0 2 2 2 2 AT hook motif TPR_MLP1_2 PF07926.12 ETS73071.1 - 1.2e-35 122.4 28.5 1.2e-35 122.4 28.5 19.0 7 6 10 18 18 18 4 TPR/MLP1/MLP2-like protein Lzipper-MIP1 PF14389.6 ETS73071.1 - 0.0019 18.4 5.5 0.0019 18.4 5.5 17.5 11 5 7 19 19 19 2 Leucine-zipper of ternary complex factor MIP1 Spectrin PF00435.21 ETS73071.1 - 0.0038 17.7 8.7 0.0038 17.7 8.7 19.5 6 4 12 21 21 21 1 Spectrin repeat SlyX PF04102.12 ETS73071.1 - 0.0094 16.5 2.8 0.0094 16.5 2.8 22.7 14 8 10 26 26 26 3 SlyX DcpS_C PF11969.8 ETS73072.1 - 6.5e-06 26.6 0.4 0.062 13.8 0.2 2.3 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding PI3K_p85B PF02192.16 ETS73072.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain Zn_clus PF00172.18 ETS73073.1 - 0.00034 20.7 5.3 0.00064 19.8 5.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_5 PF12688.7 ETS73073.1 - 0.059 13.6 0.1 2.8 8.2 0.0 2.7 2 1 0 2 2 2 0 Tetratrico peptide repeat DHR10 PF18595.1 ETS73073.1 - 0.14 12.2 2.1 0.36 10.9 2.1 1.7 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Oxidored_FMN PF00724.20 ETS73074.1 - 1.3e-88 297.6 0.0 1.5e-88 297.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 ETS73074.1 - 0.13 11.6 0.0 21 4.4 0.0 2.9 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel p450 PF00067.22 ETS73075.1 - 8.4e-67 225.9 0.0 1e-66 225.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.21 ETS73076.1 - 1.4e-32 112.6 0.0 2.2e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ETS73076.1 - 1e-27 96.4 0.0 2.5e-27 95.1 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 ETS73076.1 - 2.1e-21 75.8 0.1 4.2e-21 74.9 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 ETS73076.1 - 2.2e-05 24.7 0.0 0.0032 17.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 ETS73076.1 - 0.016 15.4 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Lyase_1 PF00206.20 ETS73077.1 - 6.1e-24 85.0 0.1 1.3e-23 83.9 0.1 1.6 1 1 0 1 1 1 1 Lyase ASL_C2 PF14698.6 ETS73077.1 - 5.5e-12 46.3 0.2 2.6e-11 44.1 0.0 2.2 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal Baculo_PEP_C PF04513.12 ETS73077.1 - 0.068 13.2 0.3 8.6 6.4 0.0 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CDH-cyt PF16010.5 ETS73078.1 - 5.5e-51 172.8 2.2 6.6e-51 172.6 2.2 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Aldo_ket_red PF00248.21 ETS73079.1 - 3.1e-54 184.2 0.0 4.2e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_S49_N PF08496.10 ETS73080.1 - 4.9 7.2 10.9 0.13 12.3 3.8 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Actin PF00022.19 ETS73081.1 - 4.4e-100 335.1 0.0 3.4e-99 332.2 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ETS73081.1 - 0.041 12.7 0.0 0.89 8.3 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein FtsA PF14450.6 ETS73081.1 - 0.056 13.9 0.0 1 9.8 0.0 2.8 2 1 0 2 2 2 0 Cell division protein FtsA F-box-like PF12937.7 ETS73082.1 - 0.022 14.7 0.1 0.05 13.5 0.1 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 ETS73082.1 - 0.054 13.4 0.4 0.14 12.1 0.4 1.7 1 0 0 1 1 1 0 F-box domain CEBP_ZZ PF16366.5 ETS73082.1 - 5.2 7.4 10.5 0.82 10.0 5.6 2.2 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain UFD1 PF03152.14 ETS73083.1 - 3.1e-28 98.4 0.0 1.8e-22 79.6 0.0 3.7 3 1 0 3 3 3 2 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 ETS73083.1 - 1.2e-06 28.7 0.1 1.2e-06 28.7 0.1 2.8 3 0 0 3 3 3 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Glyco_hydro_35 PF01301.19 ETS73084.1 - 1.8e-85 287.3 0.0 2.9e-85 286.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 ETS73084.1 - 1.1e-53 181.8 2.4 2.1e-53 180.8 2.4 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 ETS73084.1 - 8e-52 174.6 6.4 1.1e-27 96.9 0.0 3.3 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 ETS73084.1 - 1.3e-18 66.4 0.1 5e-18 64.4 0.0 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 CBM9_2 PF16011.5 ETS73085.1 - 0.00054 19.7 0.4 0.0012 18.5 0.3 1.6 1 1 0 1 1 1 1 Carbohydrate-binding family 9 GCR1_C PF12550.8 ETS73086.1 - 1.6e-22 79.6 1.7 2.8e-22 78.8 1.7 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Baculo_PEP_C PF04513.12 ETS73086.1 - 0.028 14.5 1.5 0.042 13.9 1.5 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TFIIA PF03153.13 ETS73086.1 - 1.7 8.6 12.0 2.1 8.2 12.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMEM65 PF10507.9 ETS73089.1 - 0.043 13.8 1.0 0.11 12.4 0.2 2.1 2 0 0 2 2 2 0 Transmembrane protein 65 Alph_Pro_TM PF09608.10 ETS73089.1 - 0.1 12.4 1.3 0.17 11.7 1.3 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Ion_trans PF00520.31 ETS73090.1 - 0.15 11.3 2.3 0.6 9.3 0.0 2.5 2 1 0 2 2 2 0 Ion transport protein Pribosyltran PF00156.27 ETS73091.1 - 8.4e-06 25.4 0.0 1.5e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Lipase_GDSL_2 PF13472.6 ETS73092.1 - 1.1e-21 78.0 1.6 2.4e-21 76.9 1.6 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS73092.1 - 8e-12 45.6 0.3 1.5e-11 44.7 0.3 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DAHP_synth_1 PF00793.20 ETS73093.1 - 2.8e-103 344.6 0.1 3.5e-103 344.3 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Ribosomal_L50 PF10501.9 ETS73095.1 - 2e-12 47.2 0.0 4.2e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S Abhydrolase_6 PF12697.7 ETS73096.1 - 3.6e-14 53.9 2.1 4.6e-14 53.6 2.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS73096.1 - 2.4e-11 43.7 0.6 1.7e-09 37.7 0.6 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS73096.1 - 2.7e-09 36.7 0.5 2.1e-07 30.4 0.7 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 MFS_1 PF07690.16 ETS73097.1 - 2.8e-28 98.9 29.7 2.8e-28 98.9 29.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily GTA_holin_3TM PF11351.8 ETS73097.1 - 0.41 11.2 3.0 0.4 11.2 0.3 2.3 1 1 0 2 2 2 0 Holin of 3TMs, for gene-transfer release PTR2 PF00854.21 ETS73098.1 - 1.7e-44 152.3 3.8 2.3e-44 151.8 3.8 1.1 1 0 0 1 1 1 1 POT family LAMTOR PF15454.6 ETS73099.1 - 4.2e-09 36.9 0.3 1.3e-08 35.3 0.1 1.9 2 0 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator F420_ligase PF01996.16 ETS73099.1 - 0.05 13.0 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase zf-C2H2_jaz PF12171.8 ETS73101.1 - 0.002 18.4 0.0 0.004 17.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ETS73101.1 - 0.01 16.2 0.1 0.018 15.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type OrsD PF12013.8 ETS73101.1 - 0.018 15.5 0.4 0.081 13.4 0.0 2.1 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D LST1 PF05083.13 ETS73101.1 - 0.16 12.2 0.2 0.71 10.2 0.1 2.2 2 0 0 2 2 2 0 LST-1 protein CENP-Q PF13094.6 ETS73101.1 - 5.7 7.1 15.9 0.43 10.8 10.7 1.7 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit V_ATPase_I PF01496.19 ETS73101.1 - 7 4.4 4.9 13 3.6 4.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med7 PF05983.11 ETS73102.1 - 7.1e-61 205.6 0.0 8.2e-61 205.4 0.0 1.0 1 0 0 1 1 1 1 MED7 protein DPM3 PF08285.11 ETS73105.1 - 2.1e-36 124.0 0.2 2.3e-36 123.8 0.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3007 PF11460.8 ETS73105.1 - 0.17 12.2 0.0 0.19 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) DUF4212 PF13937.6 ETS73105.1 - 0.6 10.5 3.7 0.41 11.0 1.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4212) Oxidored-like PF09791.9 ETS73107.1 - 1.3e-24 85.6 5.4 1.3e-24 85.6 5.4 1.8 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal DUF3669 PF12417.8 ETS73108.1 - 2e-21 76.0 0.1 4.1e-21 75.0 0.1 1.6 1 0 0 1 1 1 1 Zinc finger protein ADH_N PF08240.12 ETS73110.1 - 1.1e-23 83.2 3.1 1.7e-23 82.6 3.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS73110.1 - 4.6e-22 78.4 0.0 9e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS73110.1 - 1.6e-08 35.7 0.0 2.5e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ETS73110.1 - 2.7e-05 23.6 0.1 4.3e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ETS73110.1 - 6.9e-05 22.2 0.1 0.00012 21.4 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 ETS73110.1 - 0.027 14.2 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CAP PF00188.26 ETS73111.1 - 2e-08 35.1 1.2 3.4e-08 34.4 1.2 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family GRP PF07172.11 ETS73111.1 - 0.00012 22.7 1.6 0.00025 21.7 1.6 1.5 1 0 0 1 1 1 1 Glycine rich protein family FoP_duplication PF13865.6 ETS73111.1 - 2.6 8.6 8.7 5.7 7.6 8.7 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Acyl_transf_3 PF01757.22 ETS73112.1 - 2.5e-18 66.2 32.9 4.9e-18 65.3 32.9 1.5 1 1 0 1 1 1 1 Acyltransferase family FAD_binding_3 PF01494.19 ETS73113.1 - 6.1e-33 114.5 0.0 7.9e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ETS73113.1 - 2.6e-06 26.8 0.5 1.5e-05 24.2 0.5 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ETS73113.1 - 5.2e-06 26.6 0.1 1.2e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS73113.1 - 2.3e-05 23.8 0.3 0.00064 19.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ETS73113.1 - 3.6e-05 23.2 0.0 0.22 10.8 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 ETS73113.1 - 5.7e-05 22.9 0.5 9.7e-05 22.1 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS73113.1 - 6.3e-05 21.9 0.3 0.0062 15.3 0.4 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 ETS73113.1 - 8.2e-05 22.0 0.8 0.00014 21.2 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS73113.1 - 0.00031 21.2 0.3 0.00086 19.8 0.3 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ETS73113.1 - 0.00092 19.5 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ELMO_CED12 PF04727.13 ETS73113.1 - 0.0021 18.2 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family Trp_halogenase PF04820.14 ETS73113.1 - 0.0023 16.9 0.5 0.011 14.7 0.1 1.9 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_7 PF13241.6 ETS73113.1 - 0.029 14.8 0.0 0.048 14.1 0.0 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding Glu_dehyd_C PF16912.5 ETS73113.1 - 0.048 13.1 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Thi4 PF01946.17 ETS73113.1 - 0.058 12.6 0.2 0.12 11.6 0.1 1.6 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 ETS73113.1 - 0.13 11.9 1.2 2.5 7.8 0.2 2.9 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 ETS73113.1 - 0.36 9.9 2.3 0.48 9.4 1.8 1.5 2 0 0 2 2 2 0 FAD binding domain LRR_RI_capping PF18779.1 ETS73113.1 - 0.51 10.0 0.0 0.51 10.0 0.0 1.7 2 0 0 2 2 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat AXE1 PF05448.12 ETS73114.1 - 0.12 11.0 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Glyco_hydro_61 PF03443.14 ETS73115.1 - 2.6e-45 154.9 0.0 3.2e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Zn_clus PF00172.18 ETS73116.1 - 2.5e-08 33.9 7.3 5.6e-08 32.8 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3377 PF11857.8 ETS73116.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF2427 PF10348.9 ETS73117.1 - 0.22 11.3 4.0 1.4 8.7 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) Sugar_tr PF00083.24 ETS73118.1 - 1.4e-120 403.2 21.2 2.3e-120 402.5 21.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS73118.1 - 4.7e-24 85.0 38.6 2.2e-16 59.7 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Myb_DNA-binding PF00249.31 ETS73119.1 - 6.2e-09 35.9 0.6 1.5e-07 31.5 0.0 2.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ETS73119.1 - 3.4e-06 27.2 0.5 1.3e-05 25.4 0.1 2.1 1 1 1 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.8 ETS73119.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain GST_N PF02798.20 ETS73120.1 - 9.6e-13 48.3 0.0 3.4e-12 46.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ETS73120.1 - 1.2e-08 35.0 0.0 2.5e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ETS73120.1 - 2.4e-06 27.7 0.1 5.6e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ETS73120.1 - 2.8e-06 27.6 0.0 5.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS73120.1 - 6.6e-06 26.1 0.0 1.5e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ETS73120.1 - 3.1e-05 24.2 0.0 0.00014 22.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain UbiA PF01040.18 ETS73121.1 - 1.5e-59 201.3 15.8 1.7e-59 201.1 15.0 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family DUF3040 PF11239.8 ETS73121.1 - 4.2 7.7 5.4 1.2 9.4 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) BCS1_N PF08740.11 ETS73122.1 - 2.9e-33 115.4 0.1 4.5e-33 114.8 0.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 ETS73122.1 - 2.3e-17 63.7 0.0 8.6e-17 61.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ETS73122.1 - 1.3e-05 25.0 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 ETS73122.1 - 0.0067 16.0 0.1 0.24 10.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 ETS73122.1 - 0.013 15.5 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ETS73122.1 - 0.016 15.6 0.1 0.037 14.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 ETS73122.1 - 0.03 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 ETS73122.1 - 0.039 14.1 0.0 0.074 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Polyoma_lg_T_C PF06431.11 ETS73122.1 - 0.061 12.2 0.0 0.095 11.6 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus IstB_IS21 PF01695.17 ETS73122.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 ETS73122.1 - 0.11 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 ETS73122.1 - 0.12 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ETS73122.1 - 0.15 12.6 0.0 0.57 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 ETS73122.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Methyltransf_PK PF05891.12 ETS73123.1 - 2.8e-76 255.9 0.0 3.4e-76 255.6 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.12 ETS73123.1 - 6.1e-07 30.0 0.0 1e-06 29.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS73123.1 - 1.7e-06 28.6 0.0 2.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS73123.1 - 0.00053 19.8 0.0 0.0013 18.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ETS73123.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain SET PF00856.28 ETS73124.1 - 2.3e-07 31.4 0.1 5.9e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 SET domain SET PF00856.28 ETS73125.1 - 0.003 17.9 0.0 0.0033 17.8 0.0 1.1 1 0 0 1 1 1 1 SET domain TAL_FSA PF00923.19 ETS73126.1 - 1.9e-47 162.0 0.0 2.6e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DUF4451 PF14616.6 ETS73127.1 - 0.13 12.5 9.4 1.1 9.5 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4451) zf-C2H2_aberr PF17017.5 ETS73127.1 - 1.2 9.2 2.9 11 6.1 0.2 3.1 3 0 0 3 3 3 0 Aberrant zinc-finger mRNA_triPase PF02940.15 ETS73128.1 - 4.1e-53 180.3 0.0 6.4e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain RPN2_C PF18004.1 ETS73129.1 - 1.1e-48 165.1 1.9 1.1e-48 165.1 1.9 1.7 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 ETS73129.1 - 1.6e-40 135.5 20.5 1.2e-08 34.9 0.0 8.4 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 ETS73129.1 - 1.2e-19 70.5 0.0 1.5e-14 54.2 0.0 5.2 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.22 ETS73129.1 - 2e-05 24.4 0.0 3.1 8.3 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 ETS73129.1 - 2.7e-05 24.5 0.0 0.021 15.3 0.0 4.6 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 ETS73129.1 - 0.003 17.6 0.3 3.1 7.8 0.0 4.1 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Codanin-1_C PF15296.6 ETS73129.1 - 0.12 12.4 1.4 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 Codanin-1 C-terminus MFS_1 PF07690.16 ETS73130.1 - 5.8e-30 104.4 29.8 2.5e-26 92.4 13.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS73130.1 - 2.1e-27 96.1 24.2 1.6e-21 76.7 9.0 2.2 1 1 0 2 2 2 2 Sugar (and other) transporter HSP70 PF00012.20 ETS73131.1 - 7.2e-05 21.2 0.0 0.00016 20.0 0.0 1.5 2 0 0 2 2 2 1 Hsp70 protein Sec8_exocyst PF04048.14 ETS73132.1 - 0.31 10.9 3.3 8.7 6.2 0.5 3.0 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain FAM76 PF16046.5 ETS73132.1 - 0.52 9.6 5.7 0.97 8.7 5.7 1.5 1 0 0 1 1 1 0 FAM76 protein PI3K_P85_iSH2 PF16454.5 ETS73132.1 - 2.1 8.0 12.4 0.092 12.3 0.8 3.2 2 2 2 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Golgin_A5 PF09787.9 ETS73132.1 - 7.8 5.9 10.2 5.7 6.3 2.2 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 Catalase PF00199.19 ETS73133.1 - 7.4e-179 594.8 0.9 9.2e-179 594.5 0.9 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 ETS73133.1 - 4.4e-15 55.6 0.1 1e-14 54.5 0.1 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive MFS_1 PF07690.16 ETS73134.1 - 2.2e-39 135.4 34.7 2.2e-39 135.4 34.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS73134.1 - 6.2e-10 38.1 0.1 6.2e-10 38.1 0.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS73134.1 - 3.6e-07 29.4 30.2 6.8e-06 25.2 30.2 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter Xan_ur_permease PF00860.20 ETS73135.1 - 3.2e-65 220.3 36.4 7.8e-64 215.8 36.4 2.1 1 1 0 1 1 1 1 Permease family Fungal_trans PF04082.18 ETS73136.1 - 4.8e-12 45.5 0.0 8e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS73136.1 - 7.6e-05 22.8 12.9 0.00014 21.9 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.15 ETS73138.1 - 2.8e-26 93.2 0.0 5e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 ETS73138.1 - 8.3e-21 74.0 0.1 1.9e-20 72.9 0.1 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 ETS73138.1 - 8.2e-10 38.3 0.2 1.8e-09 37.2 0.2 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain SKI PF01202.22 ETS73138.1 - 1.4e-08 35.0 0.1 2.9e-08 34.0 0.1 1.5 2 0 0 2 2 2 1 Shikimate kinase Shikimate_DH PF01488.20 ETS73138.1 - 1.2e-06 28.6 0.0 2.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 ETS73138.1 - 0.0026 17.9 0.0 0.0054 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS73138.1 - 0.014 15.8 0.0 0.13 12.7 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain OCD_Mu_crystall PF02423.15 ETS73138.1 - 0.023 13.6 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Sacchrp_dh_NADP PF03435.18 ETS73138.1 - 0.082 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ABC_tran PF00005.27 ETS73138.1 - 0.097 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_8 PF12780.7 ETS73138.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 F420_oxidored PF03807.17 ETS73138.1 - 0.14 12.7 0.0 0.4 11.3 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AAA_29 PF13555.6 ETS73138.1 - 0.16 11.7 0.0 0.55 10.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AP_endonuc_2 PF01261.24 ETS73139.1 - 9.6e-34 116.7 0.0 1.6e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Carot_N PF09150.10 ETS73139.1 - 0.0095 15.8 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Orange carotenoid protein, N-terminal Sugar_tr PF00083.24 ETS73140.1 - 1.4e-135 452.6 24.0 1.7e-135 452.4 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS73140.1 - 1.3e-25 90.1 33.3 1.3e-25 90.1 33.3 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily Shikimate_dh_N PF08501.11 ETS73141.1 - 2.2e-22 79.1 0.0 4.3e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 ETS73141.1 - 0.00013 21.6 0.1 0.00028 20.6 0.1 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 ETS73141.1 - 0.028 14.5 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Inositol_P PF00459.25 ETS73142.1 - 7.4e-73 245.4 0.0 1.1e-72 244.8 0.0 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family DHquinase_II PF01220.19 ETS73143.1 - 5.8e-65 217.1 0.3 6.6e-65 217.0 0.3 1.0 1 0 0 1 1 1 1 Dehydroquinase class II ANAPC4_WD40 PF12894.7 ETS73144.1 - 2.8e-08 33.9 0.0 0.0087 16.3 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CDC45 PF02724.14 ETS73144.1 - 0.087 11.1 11.8 0.12 10.6 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nup160 PF11715.8 ETS73144.1 - 0.095 11.3 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Mpp10 PF04006.12 ETS73144.1 - 0.32 9.4 7.3 0.43 9.0 7.3 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 ETS73144.1 - 1.7 7.9 13.7 2.4 7.4 13.7 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 ETS73144.1 - 2 7.7 16.2 2.9 7.2 16.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 ETS73144.1 - 2.2 6.4 12.8 3 6.0 12.8 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 ETS73144.1 - 3.6 7.7 10.5 6.1 6.9 10.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Methyltransf_23 PF13489.6 ETS73145.1 - 3.6e-15 56.2 0.0 5.5e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS73145.1 - 2.4e-10 41.0 0.0 1.2e-09 38.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS73145.1 - 2.3e-08 34.6 0.0 5.8e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS73145.1 - 4e-08 33.2 0.0 0.0002 21.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 ETS73145.1 - 2.2e-07 31.6 0.0 3.7e-06 27.6 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 ETS73145.1 - 1.4e-05 25.3 0.0 2.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 ETS73145.1 - 0.0011 18.5 0.0 0.0026 17.3 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 ETS73145.1 - 0.0041 16.5 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 ETS73145.1 - 0.026 14.1 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 ETS73145.1 - 0.048 13.1 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 ETS73145.1 - 0.052 12.9 0.0 0.32 10.3 0.0 2.1 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 ETS73145.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Glyco_hydro_18 PF00704.28 ETS73146.1 - 3.9e-65 220.6 0.0 4.7e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MARVEL PF01284.23 ETS73147.1 - 3.5e-18 66.0 23.1 4.5e-18 65.7 23.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain Cupin_2 PF07883.11 ETS73148.1 - 3.8e-10 39.3 0.1 5.2e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Cupin domain EutQ PF06249.12 ETS73148.1 - 0.00025 20.8 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 ETS73148.1 - 0.00099 18.8 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 ETS73148.1 - 0.0019 17.8 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 ETS73148.1 - 0.011 15.7 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 AraC-like ligand binding domain MannoseP_isomer PF01050.18 ETS73148.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Peptidase_A4 PF01828.17 ETS73149.1 - 1.3e-80 269.8 19.7 1.5e-80 269.6 19.7 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF1735 PF08522.10 ETS73149.1 - 0.0065 17.1 1.8 0.51 11.0 0.1 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF1735) vMSA PF00695.19 ETS73149.1 - 0.021 13.9 0.3 0.033 13.3 0.3 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Pam16 PF03656.13 ETS73149.1 - 0.065 13.3 2.3 0.066 13.2 0.7 1.8 2 0 0 2 2 2 0 Pam16 Peptidase_A4 PF01828.17 ETS73150.1 - 1.5e-77 259.8 15.3 1.8e-77 259.5 15.3 1.1 1 0 0 1 1 1 1 Peptidase A4 family Big_6 PF17936.1 ETS73150.1 - 0.15 12.3 8.8 1.9 8.8 0.3 3.3 3 0 0 3 3 3 0 Bacterial Ig domain Bac_rhamnosid6H PF17389.2 ETS73151.1 - 2.1e-15 56.8 1.1 3.3e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 ETS73151.1 - 0.00035 20.4 0.0 0.00082 19.2 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_2_N PF02837.18 ETS73151.1 - 0.0054 16.7 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_36 PF17167.4 ETS73151.1 - 0.015 14.0 0.0 0.026 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain DUF1769 PF08588.10 ETS73153.1 - 2.3e-28 98.2 0.7 4.9e-28 97.1 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DUF3506 PF12014.8 ETS73154.1 - 1.3e-52 177.5 0.0 2.1e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 ETS73154.1 - 2.9e-06 27.0 0.2 1.1e-05 25.3 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ETS73154.1 - 2.6e-05 24.0 0.2 2.6e-05 24.0 0.2 1.6 2 0 0 2 2 2 1 F-box domain Cupin_2 PF07883.11 ETS73155.1 - 8.5e-09 35.0 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ETS73155.1 - 0.015 14.9 0.0 0.017 14.8 0.0 1.0 1 0 0 1 1 1 0 Cupin Abhydrolase_6 PF12697.7 ETS73156.1 - 3.7e-08 34.2 1.5 3.7e-08 34.2 1.5 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS73156.1 - 0.00041 20.1 0.0 0.00078 19.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 ETS73156.1 - 0.0087 15.8 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 ETS73156.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Peroxidase_2 PF01328.17 ETS73157.1 - 2.1e-46 158.8 0.0 2.9e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Unstab_antitox PF09720.10 ETS73157.1 - 0.02 15.0 0.7 0.037 14.1 0.7 1.4 1 0 0 1 1 1 0 Putative addiction module component Sugar_tr PF00083.24 ETS73158.1 - 4.6e-72 243.3 12.2 5.3e-72 243.1 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS73158.1 - 1.2e-31 110.0 28.2 1.7e-24 86.5 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS73158.1 - 0.00042 18.9 0.8 0.00042 18.9 0.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 ETS73158.1 - 0.00078 18.4 0.0 0.31 9.9 4.5 2.4 2 2 0 2 2 2 1 MFS_1 like family DUF554 PF04474.12 ETS73158.1 - 0.27 10.7 7.6 0.46 9.9 4.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF554) DUF2850 PF11012.8 ETS73159.1 - 0.051 13.9 0.1 0.06 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2850) GATase PF00117.28 ETS73160.1 - 3.1e-05 23.8 0.1 3.8e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I AA_permease_2 PF13520.6 ETS73161.1 - 2.6e-53 181.4 50.4 3.1e-53 181.1 50.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS73161.1 - 6.8e-21 74.4 43.9 9.5e-21 73.9 43.9 1.1 1 0 0 1 1 1 1 Amino acid permease SID-1_RNA_chan PF13965.6 ETS73161.1 - 6.9e-05 21.5 3.3 6.9e-05 21.5 3.3 2.5 3 0 0 3 3 3 1 dsRNA-gated channel SID-1 HATPase_c PF02518.26 ETS73162.1 - 4.2e-23 82.0 0.0 8.4e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ETS73162.1 - 5.2e-21 74.9 0.4 1.2e-20 73.8 0.4 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 ETS73162.1 - 4.3e-09 36.6 0.0 1.1e-07 32.0 0.0 2.7 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 ETS73162.1 - 1.2e-06 28.4 2.6 1.6e-06 28.0 0.1 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 ETS73162.1 - 9e-06 25.7 0.0 2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 ETS73162.1 - 6.4e-05 22.9 0.0 0.00019 21.4 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 ETS73162.1 - 0.00085 19.5 0.0 0.0029 17.8 0.0 2.0 1 0 0 1 1 1 1 PAS domain GAF_2 PF13185.6 ETS73162.1 - 0.0021 18.4 0.0 0.047 14.0 0.0 3.0 3 0 0 3 3 3 1 GAF domain HATPase_c_3 PF13589.6 ETS73162.1 - 0.11 12.4 0.0 0.38 10.6 0.0 1.9 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HLH PF00010.26 ETS73163.1 - 0.081 12.9 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Beta-lactamase PF00144.24 ETS73164.1 - 1.1e-18 67.6 0.3 1.5e-18 67.2 0.3 1.2 1 0 0 1 1 1 1 Beta-lactamase Sulfatase PF00884.23 ETS73165.1 - 8.2e-46 156.8 0.2 1.1e-45 156.4 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 ETS73165.1 - 0.046 13.3 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 ETS73165.1 - 0.051 13.8 0.8 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4976) Abhydrolase_6 PF12697.7 ETS73166.1 - 2.1e-14 54.6 0.0 2.5e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS73166.1 - 4e-13 49.6 0.3 6e-12 45.8 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS73166.1 - 1.9e-06 27.3 0.0 2.8e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PaO PF08417.12 ETS73166.1 - 0.1 12.8 0.1 0.38 10.9 0.1 2.0 2 1 0 2 2 2 0 Pheophorbide a oxygenase Iso_dh PF00180.20 ETS73167.1 - 3.4e-99 332.3 0.0 4.7e-99 331.8 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_S8 PF00410.19 ETS73169.1 - 9.5e-12 45.0 0.0 5.1e-10 39.4 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S8 GLTT PF01744.20 ETS73170.1 - 0.0002 21.0 2.0 0.0002 21.0 2.0 2.1 3 0 0 3 3 3 1 GLTT repeat (6 copies) CR6_interact PF10147.9 ETS73171.1 - 0.0066 16.2 3.7 0.014 15.1 3.7 1.5 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Shisa PF13908.6 ETS73171.1 - 0.016 15.4 0.2 0.042 14.1 0.0 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Polyketide_cyc2 PF10604.9 ETS73173.1 - 4.3e-11 43.3 0.1 5.3e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ETS73173.1 - 0.06 13.6 1.1 0.087 13.0 0.8 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport FAD_binding_4 PF01565.23 ETS73175.1 - 2.7e-15 56.3 0.2 4.7e-15 55.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS73175.1 - 1.7e-08 34.4 2.4 2.2e-08 34.1 0.9 2.0 2 0 0 2 2 2 1 Berberine and berberine like Aa_trans PF01490.18 ETS73176.1 - 1.2e-77 261.4 27.9 1.4e-77 261.1 27.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4014 PF13198.6 ETS73176.1 - 0.29 11.5 1.0 1.2 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) Serinc PF03348.15 ETS73176.1 - 7.8 5.3 9.8 1.8 7.4 0.0 2.9 3 1 0 3 3 3 0 Serine incorporator (Serinc) Nuc_deoxyri_tr2 PF15891.5 ETS73177.1 - 1.1e-29 102.9 0.0 1.6e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like NIF3 PF01784.18 ETS73178.1 - 0.00014 21.6 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) RPEL PF02755.15 ETS73179.1 - 2.1e-21 74.9 4.7 2e-10 40.0 0.8 2.5 2 0 0 2 2 2 2 RPEL repeat PBP_sp32 PF07222.12 ETS73179.1 - 0.16 11.4 4.9 0.19 11.2 4.9 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF4267 PF14087.6 ETS73180.1 - 6.1e-14 52.1 4.1 7.7e-14 51.7 4.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) E1-E2_ATPase PF00122.20 ETS73181.1 - 5.1e-35 120.6 15.1 1.2e-28 99.9 0.3 3.4 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 ETS73181.1 - 9.5e-23 80.8 6.4 9.5e-23 80.8 6.4 2.8 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ETS73181.1 - 1e-20 75.0 0.2 6.3e-19 69.1 0.2 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ETS73181.1 - 3.4e-17 62.3 0.0 9.7e-17 60.8 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ETS73181.1 - 1.5e-15 56.6 0.0 3.6e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ETS73181.1 - 4.7e-05 23.2 0.4 0.00094 19.0 0.8 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CoA_binding_3 PF13727.6 ETS73181.1 - 1.2 9.1 6.2 1.4 8.9 2.2 2.6 2 0 0 2 2 2 0 CoA-binding domain Sugar_tr PF00083.24 ETS73182.1 - 2.7e-130 435.3 24.9 3.1e-130 435.1 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS73182.1 - 7.2e-23 81.1 51.1 6.2e-20 71.4 30.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0242 PF06785.11 ETS73182.1 - 0.55 10.3 1.4 1.3 9.1 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MutS_V PF00488.21 ETS73183.1 - 4.3e-66 222.5 0.1 7.9e-66 221.7 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ETS73183.1 - 1.2e-41 143.1 0.6 7e-41 140.5 0.0 2.4 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 ETS73183.1 - 5.2e-32 110.4 0.0 1.1e-31 109.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 ETS73183.1 - 1.5e-14 54.1 1.1 4e-14 52.7 1.1 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 ETS73183.1 - 6.2e-14 52.4 2.1 8.2e-14 52.1 0.0 2.4 3 0 0 3 3 2 1 MutS domain II DUF3461 PF11944.8 ETS73183.1 - 0.072 13.2 1.6 0.16 12.1 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) AAA_29 PF13555.6 ETS73183.1 - 0.13 12.0 0.1 0.31 10.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 ETS73183.1 - 0.15 11.7 0.0 0.39 10.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ETS73183.1 - 0.22 12.0 2.1 1.1 9.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 ETS73183.1 - 0.59 9.9 2.4 0.78 9.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system CDC45 PF02724.14 ETS73183.1 - 5.5 5.2 12.1 10 4.2 12.1 1.3 1 0 0 1 1 1 0 CDC45-like protein NmrA PF05368.13 ETS73184.1 - 3.4e-43 147.9 0.0 4e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS73184.1 - 3.1e-12 46.8 0.1 4.1e-12 46.4 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 ETS73184.1 - 0.048 13.9 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain SseC PF04888.12 ETS73184.1 - 0.072 12.7 0.7 0.087 12.4 0.7 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Ribosomal_S28e PF01200.18 ETS73184.1 - 0.24 11.4 0.9 2.2 8.4 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein S28e adh_short PF00106.25 ETS73185.1 - 1.1e-41 142.4 0.0 1.5e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS73185.1 - 3.9e-29 101.9 0.0 5.8e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS73185.1 - 2.6e-07 30.7 0.2 4.1e-07 30.1 0.2 1.3 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 ETS73185.1 - 0.005 16.7 0.1 0.0078 16.1 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus Shikimate_DH PF01488.20 ETS73185.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 ETS73185.1 - 0.12 11.8 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family G_glu_transpept PF01019.21 ETS73187.1 - 1.5e-162 542.0 0.3 1.7e-162 541.8 0.3 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Fungal_trans PF04082.18 ETS73188.1 - 4.1e-11 42.4 3.3 3.4e-07 29.6 0.4 3.3 3 1 0 3 3 3 2 Fungal specific transcription factor domain Melibiase_2 PF16499.5 ETS73189.1 - 1.4e-09 37.5 0.3 2.3e-06 27.0 0.0 2.3 2 1 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 ETS73189.1 - 2e-05 24.6 0.1 4.6e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain p450 PF00067.22 ETS73190.1 - 3.4e-45 154.7 0.0 6.4e-33 114.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_43 PF04616.14 ETS73191.1 - 7.9e-70 235.4 13.9 2.1e-58 197.9 5.3 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 ETS73191.1 - 4.9e-11 42.8 2.9 0.00013 21.6 0.4 3.1 3 1 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_16 PF00722.21 ETS73192.1 - 8.1e-33 113.4 4.6 8.1e-33 113.4 4.6 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 ETS73192.1 - 1.4e-05 25.5 12.1 2.8e-05 24.5 12.1 1.4 1 0 0 1 1 1 1 Chitin recognition protein FlxA PF14282.6 ETS73193.1 - 0.0023 17.9 0.2 0.12 12.4 0.0 2.6 2 0 0 2 2 2 1 FlxA-like protein GAS PF13851.6 ETS73193.1 - 0.0061 15.9 0.6 0.0061 15.9 0.6 2.7 5 0 0 5 5 5 1 Growth-arrest specific micro-tubule binding 3HCDH_RFF PF18321.1 ETS73193.1 - 0.059 13.8 0.7 19 5.8 0.1 3.8 4 0 0 4 4 4 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain HWE_HK PF07536.14 ETS73193.1 - 0.075 13.7 0.4 0.32 11.7 0.4 2.0 1 0 0 1 1 1 0 HWE histidine kinase SKA2 PF16740.5 ETS73193.1 - 0.77 9.6 6.6 0.89 9.4 0.0 3.6 2 1 2 4 4 4 0 Spindle and kinetochore-associated protein 2 PK PF00224.21 ETS73194.1 - 8.2e-170 564.3 7.3 1e-169 563.9 7.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 ETS73194.1 - 7.6e-36 122.9 0.0 2.8e-35 121.1 0.0 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 ETS73194.1 - 6.5e-05 22.2 0.2 0.00024 20.3 0.1 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Aldedh PF00171.22 ETS73195.1 - 2.5e-147 491.2 0.0 2.9e-147 490.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ank_2 PF12796.7 ETS73196.1 - 1.9e-14 54.0 1.9 0.0013 19.3 0.0 5.9 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 ETS73196.1 - 1.4e-13 50.6 9.3 0.027 14.9 0.1 7.0 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.6 ETS73196.1 - 4.9e-11 42.9 1.2 0.035 14.7 0.0 5.3 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS73196.1 - 6.8e-11 42.2 1.0 0.00015 22.0 0.1 5.8 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS73196.1 - 4.7e-09 35.7 10.0 0.22 12.2 0.0 7.8 9 1 0 9 9 9 3 Ankyrin repeat F-box-like PF12937.7 ETS73196.1 - 0.0059 16.5 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS73196.1 - 0.087 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 F-box domain DUF924 PF06041.11 ETS73197.1 - 1.3e-18 67.8 0.0 2.1e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) AA_permease_2 PF13520.6 ETS73198.1 - 4.6e-77 259.7 23.2 5.9e-77 259.3 23.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS73198.1 - 3.2e-11 42.5 18.5 4.4e-11 42.1 18.3 1.3 1 1 0 1 1 1 1 Amino acid permease p450 PF00067.22 ETS73200.1 - 4.7e-53 180.6 0.0 6.8e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.17 ETS73200.1 - 0.059 13.3 0.2 0.15 12.0 0.1 1.7 2 0 0 2 2 2 0 Reticulon Methyltransf_23 PF13489.6 ETS73201.1 - 3.2e-18 66.1 0.0 6.4e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS73201.1 - 4.2e-11 43.4 0.0 1.7e-10 41.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS73201.1 - 1.2e-09 38.7 0.0 2.4e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS73201.1 - 2.4e-08 33.9 0.0 0.0095 15.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 ETS73201.1 - 1.3e-07 32.3 0.1 1.2e-06 29.1 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ETS73201.1 - 0.0084 15.5 0.0 0.02 14.3 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ETS73201.1 - 0.026 14.1 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 ETS73201.1 - 0.056 12.7 0.0 0.3 10.4 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase domain Adeno_PV PF03910.13 ETS73201.1 - 0.075 11.7 13.9 0.11 11.2 13.9 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV Methyltransf_16 PF10294.9 ETS73201.1 - 0.24 11.1 0.0 0.39 10.4 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Egh16-like PF11327.8 ETS73202.1 - 5e-39 134.6 11.7 7.5e-39 134.0 11.7 1.2 1 0 0 1 1 1 1 Egh16-like virulence factor Zn_clus PF00172.18 ETS73204.1 - 1.9e-19 69.5 25.5 1.2e-09 38.1 9.2 2.8 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS73204.1 - 2e-13 50.0 0.1 4.8e-13 48.7 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S10 PF00450.22 ETS73205.1 - 1.7e-103 347.3 0.7 2.1e-103 346.9 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3336 PF11815.8 ETS73206.1 - 4.4e-37 126.9 0.1 1.1e-36 125.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 ETS73206.1 - 3.5e-19 69.8 0.7 2.2e-18 67.2 0.0 2.5 3 0 0 3 3 3 1 Patatin-like phospholipase PBP1_TM PF14812.6 ETS73206.1 - 0.85 10.0 6.9 8.7 6.8 0.7 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_S9 PF00326.21 ETS73207.1 - 4e-06 26.5 0.1 0.0062 16.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ETS73207.1 - 0.049 13.3 0.0 6.9 6.2 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_GDSL_2 PF13472.6 ETS73208.1 - 3.2e-07 30.9 0.0 4.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS73208.1 - 0.00031 20.8 0.0 0.0011 19.0 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ABC2_membrane_2 PF12679.7 ETS73208.1 - 0.0064 15.8 0.6 0.023 14.0 0.1 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein Pilin_N PF07790.11 ETS73208.1 - 0.054 14.4 0.6 0.15 13.0 0.6 1.7 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal DUF4834 PF16118.5 ETS73208.1 - 0.13 13.2 0.3 0.28 12.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) LIG3_BRCT PF16759.5 ETS73208.1 - 0.14 12.5 0.6 7.9 6.9 0.0 2.3 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Spt20 PF12090.8 ETS73208.1 - 0.81 9.3 3.8 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Spt20 family SSP160 PF06933.11 ETS73208.1 - 1.1 7.3 11.6 1.5 6.9 11.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MFS_1 PF07690.16 ETS73210.1 - 4.6e-35 121.2 27.6 6.3e-35 120.7 27.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS73210.1 - 4.5e-07 29.5 10.4 6e-06 25.8 9.5 2.4 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF1772 PF08592.11 ETS73210.1 - 0.31 11.4 3.0 1.9 8.8 0.0 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF1772) Peptidase_M35 PF02102.15 ETS73211.1 - 3.1e-90 302.7 16.4 3.6e-90 302.5 16.4 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 ETS73211.1 - 3.4e-42 144.4 3.6 3.4e-42 144.4 3.6 1.6 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase BNIP3 PF06553.12 ETS73212.1 - 0.038 13.7 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 BNIP3 Abhydrolase_6 PF12697.7 ETS73213.1 - 0.05 14.2 0.0 0.26 11.8 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_61 PF03443.14 ETS73214.1 - 2.4e-61 207.3 0.3 2.4e-61 207.3 0.3 1.7 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 ETS73214.1 - 1.3e-07 31.5 9.3 3.2e-07 30.2 9.3 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain CSD PF00313.22 ETS73214.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain Cwf_Cwc_15 PF04889.12 ETS73214.1 - 2.6 7.7 4.4 3.7 7.2 4.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein adh_short_C2 PF13561.6 ETS73215.1 - 3.4e-55 187.2 2.0 4.1e-55 186.9 2.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS73215.1 - 1.7e-41 141.8 2.0 4.4e-41 140.5 1.9 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ETS73215.1 - 9.9e-17 61.4 0.8 1.3e-16 61.1 0.8 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 ETS73215.1 - 2.8e-06 27.0 0.2 1.2e-05 24.9 0.2 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ETS73215.1 - 6.1e-06 25.9 0.6 4.1e-05 23.2 0.6 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ETS73215.1 - 0.0065 16.7 0.1 0.012 15.9 0.1 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 ETS73215.1 - 0.008 15.3 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 ETS73215.1 - 0.0087 16.6 0.4 1.3 9.7 0.2 2.6 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent E1_dh PF00676.20 ETS73215.1 - 0.054 12.4 0.0 0.087 11.8 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Shikimate_DH PF01488.20 ETS73215.1 - 0.17 11.9 0.1 0.35 10.9 0.1 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CTP_transf_like PF01467.26 ETS73216.1 - 8.3e-05 22.8 0.0 0.00019 21.6 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase-like WD40 PF00400.32 ETS73217.1 - 2.2e-13 50.5 6.1 1.6e-05 25.6 0.0 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ADH_zinc_N PF00107.26 ETS73218.1 - 1e-25 90.2 0.2 2.1e-25 89.2 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS73218.1 - 6.1e-14 53.2 0.0 1.1e-13 52.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS73218.1 - 1.8e-05 24.6 0.0 7.8e-05 22.5 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ETS73218.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Spt5-NGN PF03439.13 ETS73219.1 - 6.8e-24 83.6 0.0 1.2e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 ETS73219.1 - 7.2e-19 68.6 8.7 7.2e-19 68.6 8.7 3.4 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 ETS73219.1 - 4.3e-15 56.0 25.2 5.1e-12 46.2 13.0 4.9 2 1 2 4 4 4 3 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 ETS73219.1 - 3.9e-07 29.8 16.5 0.0017 18.2 1.2 5.5 6 0 0 6 6 6 2 KOW motif Cornifin PF02389.15 ETS73219.1 - 0.0065 16.7 2.1 0.014 15.6 2.1 1.5 1 0 0 1 1 1 1 Cornifin (SPRR) family DUF3912 PF13051.6 ETS73219.1 - 0.038 14.2 2.7 0.16 12.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) Glyco_hydro_61 PF03443.14 ETS73220.1 - 6.8e-63 212.3 0.1 8.2e-63 212.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ETS73220.1 - 0.061 14.0 0.0 0.075 13.7 0.0 1.3 1 0 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading DUF4705 PF15788.5 ETS73220.1 - 0.061 13.6 1.1 0.15 12.3 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4705) Glyco_hydro_79C PF16862.5 ETS73222.1 - 3.5e-20 72.8 3.7 3.5e-20 72.8 1.4 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain NQR2_RnfD_RnfE PF03116.15 ETS73222.1 - 0.014 14.9 3.3 0.021 14.2 3.3 1.3 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family Pkinase PF00069.25 ETS73224.1 - 1.2e-43 149.4 0.0 4.2e-43 147.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS73224.1 - 2.2e-31 109.1 0.0 3.6e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ETS73224.1 - 0.089 12.1 0.1 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RPE65 PF03055.15 ETS73225.1 - 7.2e-121 404.6 0.0 8.2e-121 404.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Bac_rhodopsin PF01036.18 ETS73226.1 - 1.3e-58 198.2 9.2 1.8e-58 197.8 9.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein CHRD PF07452.12 ETS73227.1 - 3.3e-08 34.5 0.0 5.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 CHRD domain FYTT PF07078.11 ETS73230.1 - 7.1e-09 35.4 4.6 2.9e-05 23.6 1.7 2.1 1 1 1 2 2 2 2 Forty-two-three protein CENP-N PF05238.13 ETS73230.1 - 0.054 12.8 2.4 0.064 12.6 2.4 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like BSP_II PF05432.11 ETS73230.1 - 0.058 13.1 6.4 0.076 12.7 6.4 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Atrophin-1 PF03154.15 ETS73230.1 - 0.11 10.7 6.5 0.14 10.4 6.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family BHD_2 PF10404.9 ETS73230.1 - 1.4 9.9 6.3 4.2 8.4 6.3 1.7 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 2 FAM178 PF14816.6 ETS73230.1 - 4 6.3 6.9 5.3 5.9 6.9 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 APC_rep PF18797.1 ETS73231.1 - 0.12 13.4 0.0 0.14 13.1 0.0 1.2 1 0 0 1 1 1 0 Adenomatous polyposis coli (APC) repeat BUD22 PF09073.10 ETS73232.1 - 2.4 7.4 28.7 4.7 6.4 28.7 1.4 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 ETS73232.1 - 6.9 5.1 12.5 10 4.5 12.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 ETS73232.1 - 8.2 5.7 28.7 14 5.0 28.7 1.3 1 0 0 1 1 1 0 SDA1 Na_H_antiport_2 PF13726.6 ETS73234.1 - 0.014 15.6 1.2 0.049 13.8 1.2 1.9 1 1 0 1 1 1 0 Na+-H+ antiporter family NADH_Oxid_Nqo15 PF11497.8 ETS73235.1 - 0.033 14.2 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 Pox_Ag35 PF03286.14 ETS73236.1 - 1.2 8.9 11.7 3.1 7.5 11.7 1.8 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Dicty_REP PF05086.12 ETS73236.1 - 7.8 4.3 7.6 11 3.9 7.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FoP_duplication PF13865.6 ETS73238.1 - 0.002 18.7 14.3 0.0022 18.5 7.9 3.0 2 2 0 2 2 2 2 C-terminal duplication domain of Friend of PRMT1 CPDase PF07823.11 ETS73239.1 - 0.15 11.7 0.0 1.1 8.9 0.0 2.0 2 0 0 2 2 2 0 Cyclic phosphodiesterase-like protein Ribosomal_60s PF00428.19 ETS73240.1 - 0.4 11.3 8.7 5.2 7.7 2.0 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein TMEM51 PF15345.6 ETS73241.1 - 0.098 12.5 2.3 0.12 12.2 2.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 FAM76 PF16046.5 ETS73242.1 - 6.1e-09 35.7 91.6 0.003 17.0 5.4 8.0 2 2 6 8 8 8 8 FAM76 protein Spc7 PF08317.11 ETS73242.1 - 7.9e-06 25.0 109.7 0.015 14.2 14.8 6.9 2 1 4 7 7 7 6 Spc7 kinetochore protein Exonuc_VII_S PF02609.16 ETS73242.1 - 0.0015 18.5 0.8 0.0015 18.5 0.8 3.6 4 0 0 4 4 4 1 Exonuclease VII small subunit DUF3552 PF12072.8 ETS73242.1 - 0.005 16.3 13.8 0.005 16.3 13.8 8.1 2 2 6 8 8 8 3 Domain of unknown function (DUF3552) DUF745 PF05335.13 ETS73242.1 - 0.0093 15.7 3.8 0.0093 15.7 3.8 6.7 4 1 3 7 7 7 2 Protein of unknown function (DUF745) eIF3m_C_helix PF18005.1 ETS73242.1 - 0.11 12.3 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix ATP-synt_E_2 PF08112.11 ETS73242.1 - 0.12 12.7 18.0 2 8.7 0.7 5.1 4 0 0 4 4 4 0 ATP synthase epsilon subunit Fez1 PF06818.15 ETS73242.1 - 0.65 10.4 100.4 0.016 15.6 14.2 6.5 2 2 4 6 6 6 0 Fez1 Cast PF10174.9 ETS73242.1 - 9.2 4.3 104.2 0.0041 15.4 22.1 4.8 1 1 1 3 3 3 0 RIM-binding protein of the cytomatrix active zone ATG16 PF08614.11 ETS73242.1 - 9.3 6.4 112.7 0.59 10.3 20.2 7.5 2 1 5 8 8 8 0 Autophagy protein 16 (ATG16) T5orf172 PF10544.9 ETS73245.1 - 0.14 12.7 0.5 1.1 9.9 0.0 2.3 2 0 0 2 2 2 0 T5orf172 domain Lactamase_B_2 PF12706.7 ETS73246.1 - 2.4e-07 30.5 0.0 4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ETS73246.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DRMBL PF07522.14 ETS73247.1 - 0.0044 17.2 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase PI-PLC-X PF00388.19 ETS73248.1 - 1.2e-63 213.0 0.1 2.1e-63 212.3 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 ETS73248.1 - 7.8e-43 145.5 0.0 1.6e-42 144.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 ETS73248.1 - 5.9e-06 26.5 0.0 2.3e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 C2 domain EF-hand_like PF09279.11 ETS73248.1 - 0.029 14.9 0.0 0.62 10.6 0.0 2.6 1 1 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like peroxidase PF00141.23 ETS73249.1 - 1.1e-31 110.3 0.8 1.5e-31 109.9 0.8 1.1 1 0 0 1 1 1 1 Peroxidase F-box-like PF12937.7 ETS73249.1 - 0.047 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 F-box-like Fungal_trans PF04082.18 ETS73250.1 - 7.6e-19 67.8 0.0 1e-17 64.1 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS73250.1 - 1.8e-09 37.5 11.0 3e-09 36.9 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 ETS73251.1 - 1e-13 51.3 0.0 3e-13 49.7 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS73251.1 - 0.0013 18.4 0.1 0.0035 17.0 0.1 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS73251.1 - 0.068 12.4 0.0 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CcmH PF03918.14 ETS73252.1 - 0.0083 15.4 0.8 0.42 9.9 0.0 2.4 1 1 0 2 2 2 2 Cytochrome C biogenesis protein NOA36 PF06524.12 ETS73252.1 - 2.5 7.4 9.8 4.9 6.4 9.8 1.5 1 0 0 1 1 1 0 NOA36 protein IQCJ-SCHIP1 PF15157.6 ETS73253.1 - 0.076 12.9 0.0 0.095 12.5 0.0 1.2 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Gpi16 PF04113.14 ETS73254.1 - 1.1e-246 819.7 0.0 1.3e-246 819.4 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.15 ETS73255.1 - 5.9e-71 239.1 0.0 7.1e-71 238.8 0.0 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Jnk-SapK_ap_N PF09744.9 ETS73255.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 gpW PF02831.15 ETS73255.1 - 0.18 11.7 0.9 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 gpW U79_P34 PF03064.16 ETS73256.1 - 0.21 10.9 16.1 0.43 9.9 16.1 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TFIIA PF03153.13 ETS73256.1 - 1.3 9.0 16.3 1.6 8.6 16.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1479 PF07350.12 ETS73257.1 - 8.4e-155 515.6 0.0 1e-154 515.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) GMC_oxred_N PF00732.19 ETS73259.1 - 1.5e-51 175.6 0.0 1.9e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS73259.1 - 7.8e-29 101.1 0.0 1.4e-28 100.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS73259.1 - 7e-09 35.3 0.0 0.00047 19.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS73259.1 - 2.4e-05 24.5 0.1 5.7e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS73259.1 - 8.9e-05 22.2 0.9 0.00061 19.5 0.9 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ETS73259.1 - 0.00096 18.5 0.1 0.002 17.4 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 ETS73259.1 - 0.0025 17.1 0.1 0.0062 15.8 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS73259.1 - 0.028 13.7 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 ETS73259.1 - 0.031 13.3 0.0 0.07 12.2 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ETS73259.1 - 0.04 13.2 0.1 1.2 8.3 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS73259.1 - 0.041 12.6 0.0 0.23 10.1 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Sugar_tr PF00083.24 ETS73260.1 - 3.6e-125 418.4 21.5 4.1e-125 418.2 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS73260.1 - 1.1e-26 93.7 65.9 3.7e-24 85.3 28.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cu_amine_oxid PF01179.20 ETS73261.1 - 1.9e-121 405.9 1.4 2.4e-121 405.5 1.4 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 ETS73261.1 - 6.9e-07 29.0 0.1 1.7e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 ETS73261.1 - 0.0003 20.9 0.0 0.00062 19.9 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Tyrosinase PF00264.20 ETS73262.1 - 2e-36 126.4 6.9 6.2e-36 124.8 6.9 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase DUF885 PF05960.11 ETS73264.1 - 7.9e-46 157.8 0.1 1.3e-45 157.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) SpoOE-like PF09388.10 ETS73264.1 - 0.11 12.5 1.1 0.19 11.7 0.1 2.0 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein Asparaginase_2 PF01112.18 ETS73265.1 - 7.7e-54 182.8 0.8 8.2e-26 90.7 0.0 3.8 3 1 0 3 3 3 3 Asparaginase Tim17 PF02466.19 ETS73266.1 - 1.9e-32 111.9 7.9 2.4e-32 111.6 7.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 ETS73266.1 - 0.047 13.8 5.5 0.075 13.2 0.6 2.3 2 1 0 2 2 2 0 LydA holin phage, holin superfamily III Sugar_tr PF00083.24 ETS73267.1 - 7.5e-110 367.9 22.2 1e-109 367.4 22.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS73267.1 - 1.2e-21 77.0 66.1 1.4e-17 63.7 32.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS73267.1 - 1.1e-07 30.7 7.8 6.3e-06 24.9 2.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Peptidase_M20 PF01546.28 ETS73268.1 - 2.9e-24 85.9 0.0 1e-23 84.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 ETS73268.1 - 2.2e-15 56.8 4.4 0.0051 17.6 0.0 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat M20_dimer PF07687.14 ETS73268.1 - 2.4e-05 24.2 0.0 5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ETS73268.1 - 0.00045 20.0 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PQQ_3 PF13570.6 ETS73268.1 - 0.95 10.0 2.7 5.1 7.7 0.0 3.6 5 0 0 5 5 5 0 PQQ-like domain GH131_N PF18271.1 ETS73269.1 - 1.3e-66 224.9 2.3 1.3e-66 224.9 2.3 1.5 2 0 0 2 2 2 1 Glycoside hydrolase 131 catalytic N-terminal domain DPBB_1 PF03330.18 ETS73272.1 - 1e-08 35.3 3.3 4.2e-08 33.3 0.3 3.0 2 2 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 ETS73272.1 - 0.00016 21.7 1.3 0.00034 20.6 0.9 1.7 2 0 0 2 2 2 1 Pollen allergen InPase PF18823.1 ETS73272.1 - 0.044 13.5 0.1 0.083 12.6 0.1 1.4 1 0 0 1 1 1 0 Inorganic Pyrophosphatase CHB_HEX_C PF03174.13 ETS73272.1 - 0.19 11.7 0.3 0.44 10.5 0.3 1.6 1 1 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain Clr5 PF14420.6 ETS73273.1 - 6.7e-21 74.3 2.4 1.4e-20 73.2 2.4 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_16 PF13432.6 ETS73273.1 - 0.026 15.2 0.1 0.066 13.9 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 ETS73273.1 - 0.029 14.9 0.7 0.051 14.1 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 ETS73273.1 - 0.066 14.1 0.2 3.9 8.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ATG27 PF09451.10 ETS73274.1 - 8.4e-91 304.5 0.0 1e-90 304.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 FAM83 PF07894.12 ETS73274.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 FAM83 A-H Spt20 PF12090.8 ETS73275.1 - 3.6e-50 170.8 0.1 3.6e-50 170.8 0.1 7.3 3 2 2 5 5 5 1 Spt20 family DUF4010 PF13194.6 ETS73276.1 - 0.072 12.8 0.0 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) Hexapep PF00132.24 ETS73277.1 - 1.1e-06 28.1 1.0 0.00087 18.9 0.7 3.1 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 ETS73277.1 - 0.0003 19.8 1.2 0.0013 17.8 1.1 1.8 1 1 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 ETS73277.1 - 0.0011 17.2 0.1 0.0015 16.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 ETS73277.1 - 0.0012 19.2 0.0 0.0026 18.1 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 ETS73277.1 - 0.043 13.4 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase DUF5554 PF17709.1 ETS73277.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5554) Hexapep_2 PF14602.6 ETS73277.1 - 0.08 12.7 5.2 9.8 6.0 3.2 3.2 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase zf-C2H2 PF00096.26 ETS73278.1 - 0.00057 20.2 13.2 0.21 12.1 5.0 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS73278.1 - 0.012 16.4 11.5 0.7 10.9 3.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 ETS73278.1 - 0.015 15.2 0.5 0.04 13.8 0.5 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 ETS73278.1 - 0.017 15.4 4.6 0.031 14.6 4.6 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 ETS73278.1 - 0.12 13.0 3.3 0.19 12.4 0.8 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 ETS73278.1 - 1.6 9.3 12.2 0.23 12.0 4.7 2.8 2 0 0 2 2 2 0 Zinc-finger double domain Ribosomal_S24e PF01282.19 ETS73279.1 - 4.4e-34 116.3 0.0 7.6e-34 115.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e LRR_4 PF12799.7 ETS73280.1 - 0.0049 17.3 0.6 3.2 8.3 0.0 4.3 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ETS73280.1 - 0.0062 16.5 0.6 3.6 7.9 0.0 3.8 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 ETS73280.1 - 0.17 12.5 3.3 11 7.0 0.1 4.8 5 1 0 5 5 5 0 Leucine Rich Repeat adh_short_C2 PF13561.6 ETS73281.1 - 4.4e-59 199.9 2.6 5.8e-59 199.5 2.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS73281.1 - 8.1e-47 159.2 1.8 1e-46 158.9 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS73281.1 - 4e-08 33.4 0.5 1.1e-07 32.0 0.5 1.6 1 1 0 1 1 1 1 KR domain Dioxygenase_C PF00775.21 ETS73282.1 - 2.5e-08 33.6 0.0 4.8e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 Dioxygenase Pec_lyase_C PF00544.19 ETS73283.1 - 7.4e-26 91.0 3.0 1.2e-24 87.1 3.0 2.3 1 1 0 1 1 1 1 Pectate lyase Mito_carr PF00153.27 ETS73284.1 - 8e-43 144.3 8.3 1.7e-15 56.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NAD_binding_10 PF13460.6 ETS73285.1 - 2.2e-09 37.5 0.0 2.7e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS73285.1 - 7.9e-08 32.1 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS73285.1 - 7.6e-05 21.8 0.0 0.0001 21.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ETS73285.1 - 0.00012 21.4 0.0 0.28 10.3 0.0 2.1 1 1 0 2 2 2 2 Male sterility protein DapB_N PF01113.20 ETS73285.1 - 0.00026 21.1 0.1 0.00043 20.4 0.1 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 ETS73285.1 - 0.01 14.9 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 ETS73285.1 - 0.014 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Sacchrp_dh_NADP PF03435.18 ETS73285.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 ETS73285.1 - 0.041 14.3 0.0 0.066 13.7 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 ETS73285.1 - 0.07 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GFO_IDH_MocA PF01408.22 ETS73286.1 - 6.4e-16 59.3 0.0 1.1e-15 58.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 ETS73286.1 - 0.022 15.4 0.1 0.038 14.6 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain BCA_ABC_TP_C PF12399.8 ETS73286.1 - 0.037 13.9 0.1 0.099 12.6 0.1 1.8 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter Zn_clus PF00172.18 ETS73287.1 - 4.4e-05 23.5 7.3 8.8e-05 22.6 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS73287.1 - 0.0041 16.2 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 ETS73288.1 - 1.6e-73 248.0 0.0 2.2e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 ETS73288.1 - 4.2e-28 98.5 0.0 6.6e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ETS73288.1 - 1.2e-24 87.2 0.1 3.1e-24 85.8 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 ETS73288.1 - 3.8e-12 46.8 0.0 9.7e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 ETS73288.1 - 0.0025 18.1 0.0 0.0078 16.5 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin domain DUF1400 PF07176.11 ETS73288.1 - 0.069 13.4 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) FAD_binding_6 PF00970.24 ETS73288.1 - 0.17 12.3 0.0 0.8 10.1 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ETS73288.1 - 0.21 11.7 0.0 4.2 7.5 0.0 2.6 2 1 1 3 3 3 0 Ferric reductase NAD binding domain adh_short_C2 PF13561.6 ETS73289.1 - 8e-61 205.6 0.7 1e-60 205.2 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS73289.1 - 4.2e-46 156.9 2.2 5.2e-46 156.6 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 ETS73289.1 - 0.00064 19.3 0.2 0.0033 16.9 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ETS73289.1 - 0.0044 17.0 0.2 0.0065 16.4 0.2 1.2 1 0 0 1 1 1 1 KR domain DLH PF01738.18 ETS73290.1 - 2e-20 73.3 0.0 2.3e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family MFS_1 PF07690.16 ETS73291.1 - 1.5e-32 112.9 28.1 1.9e-32 112.5 28.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2627 PF11118.8 ETS73291.1 - 1.9 9.1 0.0 1.9 9.1 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2627) Peptidase_M35 PF02102.15 ETS73292.1 - 2.4e-80 270.1 17.9 2.6e-80 270.0 17.9 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 ETS73292.1 - 5.6e-43 147.0 3.9 5.6e-43 147.0 3.9 1.6 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase SNAD1 PF18744.1 ETS73292.1 - 0.057 13.3 0.2 0.11 12.4 0.0 1.5 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 1 MmgE_PrpD PF03972.14 ETS73293.1 - 1.3e-118 396.4 3.8 1.5e-118 396.1 3.8 1.0 1 0 0 1 1 1 1 MmgE/PrpD family ADH_zinc_N PF00107.26 ETS73294.1 - 1.5e-20 73.5 0.0 2.2e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ETS73294.1 - 2.5e-14 53.1 0.0 5.4e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ETS73294.1 - 1.2e-05 26.4 0.0 3e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GYF PF02213.16 ETS73294.1 - 0.015 14.9 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 GYF domain Fungal_trans PF04082.18 ETS73296.1 - 9.6e-26 90.4 0.0 1.8e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS73296.1 - 6.8e-09 35.7 8.5 1.2e-08 34.9 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS73297.1 - 7.7e-52 176.4 0.0 1e-51 176.0 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS73297.1 - 1.2e-05 25.4 6.9 1.2e-05 25.4 6.9 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Syndecan PF01034.20 ETS73298.1 - 0.059 13.3 1.7 0.12 12.3 1.7 1.4 1 0 0 1 1 1 0 Syndecan domain Glycophorin_A PF01102.18 ETS73298.1 - 0.23 11.7 1.8 1.1 9.5 1.4 2.4 1 1 1 2 2 2 0 Glycophorin A NUDIX PF00293.28 ETS73299.1 - 4.3e-17 62.4 0.0 7.2e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 ETS73299.1 - 0.0047 16.9 0.0 0.013 15.5 0.0 1.9 1 1 0 1 1 1 1 NUDIX domain MFS_1 PF07690.16 ETS73300.1 - 7.1e-21 74.5 35.3 6.3e-20 71.4 29.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS73300.1 - 3.5e-05 22.9 24.7 0.0038 16.1 21.9 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2811 PF10929.8 ETS73300.1 - 0.12 12.6 0.1 0.31 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) Pox_A14 PF05767.12 ETS73300.1 - 0.14 12.3 1.2 0.6 10.3 1.2 2.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 TRIQK PF15168.6 ETS73300.1 - 0.24 11.3 0.7 0.94 9.4 0.3 2.2 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Ndc1_Nup PF09531.10 ETS73301.1 - 1.5 7.4 9.4 1.7 7.3 9.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hamartin PF04388.12 ETS73301.1 - 1.9 7.0 10.3 2.2 6.8 10.3 1.0 1 0 0 1 1 1 0 Hamartin protein Zn_clus PF00172.18 ETS73302.1 - 8.4e-08 32.2 10.7 8.4e-08 32.2 10.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS73302.1 - 3.2e-06 26.4 0.0 5.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PspA_IM30 PF04012.12 ETS73302.1 - 0.074 12.6 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 PspA/IM30 family ESAG1 PF03238.13 ETS73303.1 - 0.003 17.0 0.2 0.034 13.6 0.0 2.1 2 0 0 2 2 2 1 ESAG protein Amidohydro_1 PF01979.20 ETS73304.1 - 4.5e-19 69.0 0.8 6.1e-18 65.2 0.8 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS73304.1 - 1.4e-13 51.2 1.3 1.4e-06 28.0 0.0 2.9 2 1 0 3 3 3 2 Amidohydrolase family TPR_MLP1_2 PF07926.12 ETS73304.1 - 0.37 10.9 2.0 0.67 10.0 2.0 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TRCF PF03461.15 ETS73306.1 - 0.036 14.5 0.0 0.065 13.6 0.0 1.3 1 0 0 1 1 1 0 TRCF domain Pho88 PF10032.9 ETS73307.1 - 7.6e-83 276.2 0.2 8.5e-83 276.1 0.2 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) XPA_C PF05181.12 ETS73308.1 - 1.2e-26 92.4 1.3 2.4e-26 91.5 1.3 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 ETS73308.1 - 0.00017 21.5 1.8 0.00017 21.5 1.8 1.8 2 0 0 2 2 2 1 XPA protein N-terminal TF_Zn_Ribbon PF08271.12 ETS73308.1 - 0.32 10.6 5.7 6.9 6.3 1.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Pribosyltran_N PF13793.6 ETS73309.1 - 1.3e-43 147.7 0.1 3.7e-43 146.2 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 ETS73309.1 - 6.3e-42 143.7 1.7 3.2e-36 125.1 0.7 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 ETS73309.1 - 1e-15 57.6 1.2 2.3e-15 56.4 0.8 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ETS73309.1 - 0.0087 15.5 0.2 0.017 14.6 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Ribosomal_S6e PF01092.19 ETS73310.1 - 8e-59 197.1 0.0 1.6e-58 196.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e ALS2CR8 PF15299.6 ETS73310.1 - 0.028 14.3 0.7 0.033 14.1 0.7 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Atg14 PF10186.9 ETS73310.1 - 0.98 8.4 7.8 1.3 8.0 7.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ctf8 PF09696.10 ETS73311.1 - 5.4e-44 150.0 0.1 8.4e-44 149.4 0.1 1.3 1 0 0 1 1 1 1 Ctf8 MFS_1 PF07690.16 ETS73312.1 - 1.9e-35 122.5 44.2 2e-33 115.8 24.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS73312.1 - 0.004 16.1 0.1 0.004 16.1 0.1 2.4 2 1 0 2 2 2 1 MFS_1 like family PTH2 PF01981.16 ETS73314.1 - 9e-46 155.0 0.2 1.4e-45 154.4 0.2 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Baculo_PEP_C PF04513.12 ETS73315.1 - 5.5e-08 33.0 25.3 0.027 14.5 1.9 5.3 3 1 1 5 5 5 4 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 ETS73315.1 - 0.00029 20.9 29.3 0.46 10.6 0.0 5.4 4 1 0 4 4 4 3 TPR/MLP1/MLP2-like protein Sec16 PF12932.7 ETS73315.1 - 0.31 11.7 1.9 77 3.9 0.7 3.6 2 1 1 3 3 3 0 Vesicle coat trafficking protein Sec16 mid-region ApoO PF09769.9 ETS73315.1 - 0.36 10.8 5.4 0.38 10.7 0.2 3.5 3 1 1 4 4 4 0 Apolipoprotein O Hrs_helical PF12210.8 ETS73315.1 - 0.38 11.3 10.4 0.041 14.4 2.2 3.4 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate VASP_tetra PF08776.11 ETS73315.1 - 0.56 9.8 5.3 1.2 8.8 0.1 3.6 3 0 0 3 3 3 0 VASP tetramerisation domain HisKA_3 PF07730.13 ETS73315.1 - 0.87 10.2 8.6 14 6.3 0.2 4.5 2 1 2 4 4 4 0 Histidine kinase Filament PF00038.21 ETS73315.1 - 1.2 8.7 36.7 2.3 7.7 22.5 3.9 3 1 1 4 4 4 0 Intermediate filament protein FlaC_arch PF05377.11 ETS73315.1 - 1.5 9.3 23.9 3 8.3 1.5 6.5 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) SAM_Exu PF18609.1 ETS73315.1 - 1.9 8.6 4.5 2.2 8.4 0.1 3.4 3 1 1 4 4 4 0 Exuperantia SAM-like domain BLOC1_2 PF10046.9 ETS73315.1 - 3.8 7.9 27.5 11 6.4 2.3 6.8 5 2 1 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FUSC PF04632.12 ETS73315.1 - 4.2 5.8 8.9 0.49 8.9 3.2 2.2 2 1 0 2 2 2 0 Fusaric acid resistance protein family DUF3086 PF11285.8 ETS73315.1 - 7.4 5.6 14.8 0.042 13.0 1.5 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3086) TIP49 PF06068.13 ETS73316.1 - 3.1e-154 513.4 2.7 4e-154 513.1 2.7 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 ETS73316.1 - 5e-22 77.8 0.1 3.6e-21 75.0 0.1 2.4 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 ETS73316.1 - 3.3e-08 34.0 0.3 5.1e-05 23.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ETS73316.1 - 2.2e-07 30.7 0.3 0.0001 22.1 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 ETS73316.1 - 2e-06 27.3 0.8 3.8e-06 26.4 0.8 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 ETS73316.1 - 4.9e-05 23.8 0.1 0.00013 22.4 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 ETS73316.1 - 0.00084 18.8 0.7 0.0083 15.5 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 ETS73316.1 - 0.029 14.7 2.8 2 8.8 2.8 2.6 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ETS73316.1 - 0.03 14.0 0.0 6.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 ETS73316.1 - 0.037 13.8 0.8 0.35 10.6 0.8 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ETS73316.1 - 0.05 13.6 0.1 3.4 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ETS73316.1 - 0.054 13.1 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ETS73316.1 - 0.11 12.7 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ETS73316.1 - 0.16 11.4 0.2 0.64 9.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Gp_dh_C PF02800.20 ETS73317.1 - 6.1e-71 237.1 0.2 8.4e-71 236.7 0.2 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 ETS73317.1 - 6.3e-39 132.4 0.0 1.4e-38 131.3 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 ETS73317.1 - 0.007 16.5 0.4 0.057 13.5 0.0 2.4 2 1 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 ETS73317.1 - 0.082 12.3 0.1 0.51 9.7 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 ETS73318.1 - 1.4e-17 63.6 0.0 2e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 ETS73318.1 - 6.2e-07 29.6 0.0 3.2e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFA PF04828.14 ETS73319.1 - 2.7e-13 50.0 9.6 1.4e-06 28.5 0.7 2.7 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme AP_endonuc_2 PF01261.24 ETS73320.1 - 4.9e-36 124.2 0.3 9.3e-36 123.2 0.1 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel ATP-grasp PF02222.22 ETS73320.1 - 0.15 11.7 0.0 0.38 10.3 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp domain DHquinase_I PF01487.15 ETS73321.1 - 1.7e-23 84.1 0.0 5e-23 82.5 0.0 1.7 2 0 0 2 2 2 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 ETS73321.1 - 6.4e-19 68.0 0.0 3.8e-18 65.5 0.0 2.2 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 ETS73321.1 - 5.6e-16 59.1 0.0 1.1e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase SDH_C PF18317.1 ETS73321.1 - 1.9e-08 34.0 0.1 3.7e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 ETS73321.1 - 4.3e-07 30.1 0.1 1.2e-06 28.6 0.1 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.15 ETS73321.1 - 0.053 12.5 0.1 0.09 11.7 0.1 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Fungal_trans PF04082.18 ETS73322.1 - 6.7e-13 48.3 0.8 1.1e-12 47.5 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS73322.1 - 1.1e-08 35.1 11.3 2.1e-08 34.1 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Shikimate_dh_N PF08501.11 ETS73323.1 - 1.4e-20 73.3 0.0 2.9e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 ETS73323.1 - 3.6e-10 39.4 0.2 6.3e-10 38.6 0.2 1.4 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 ETS73323.1 - 3.3e-06 27.2 0.0 5.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ETS73323.1 - 0.025 14.8 0.0 0.052 13.8 0.0 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain eRF1_3 PF03465.15 ETS73323.1 - 0.064 13.7 0.0 0.1 13.1 0.0 1.4 1 1 0 1 1 1 0 eRF1 domain 3 GFO_IDH_MocA PF01408.22 ETS73323.1 - 0.076 13.9 0.0 0.17 12.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 ETS73323.1 - 0.14 12.7 0.1 0.27 11.9 0.1 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Dioxygenase_C PF00775.21 ETS73324.1 - 8.8e-37 126.3 0.0 1.2e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 ETS73324.1 - 9.4e-28 95.9 0.0 2.4e-27 94.6 0.0 1.7 2 0 0 2 2 2 1 Catechol dioxygenase N terminus Fe-ADH PF00465.19 ETS73325.1 - 3.4e-71 240.0 0.1 4e-71 239.7 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ETS73325.1 - 1.2e-10 41.6 0.0 1.6e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase GrpB PF04229.14 ETS73326.1 - 3.7e-45 154.0 0.1 5.6e-45 153.4 0.1 1.3 1 0 0 1 1 1 1 GrpB protein DUF2508 PF10704.9 ETS73326.1 - 0.063 13.5 0.1 0.37 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Shikimate_dh_N PF08501.11 ETS73327.1 - 1.9e-17 63.3 0.0 5.6e-17 61.8 0.0 1.8 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 ETS73327.1 - 0.0019 18.3 0.1 0.005 16.9 0.1 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GARS_N PF02844.15 ETS73327.1 - 0.13 13.1 0.1 0.78 10.6 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain OCD_Mu_crystall PF02423.15 ETS73327.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family SnoaL_4 PF13577.6 ETS73328.1 - 1.2e-08 35.1 0.1 1.8e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 ETS73328.1 - 0.0032 17.7 0.5 0.0048 17.2 0.5 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ETS73328.1 - 0.0058 17.0 0.1 0.012 16.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 ETS73328.1 - 0.061 14.0 0.3 0.1 13.3 0.3 1.3 1 0 0 1 1 1 0 SnoaL-like domain FAD_binding_4 PF01565.23 ETS73329.1 - 4.2e-24 84.9 0.9 7.5e-24 84.1 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain WSC PF01822.19 ETS73330.1 - 1.4e-12 47.6 8.8 1.4e-12 47.6 8.8 3.5 2 1 0 2 2 2 1 WSC domain p450 PF00067.22 ETS73331.1 - 1.2e-67 228.7 0.0 1.6e-67 228.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 ETS73331.1 - 2.4e-67 227.4 0.0 3.4e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS73331.1 - 2.6e-18 66.8 0.1 6.4e-18 65.5 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SMRP1 PF15181.6 ETS73331.1 - 0.13 11.9 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 ADH_zinc_N PF00107.26 ETS73332.1 - 1.5e-22 80.0 0.2 2.2e-22 79.5 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS73332.1 - 2.1e-10 41.8 0.0 3.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS73332.1 - 1.4e-05 24.9 0.0 3.7e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CDC45 PF02724.14 ETS73332.1 - 0.23 9.7 0.0 0.33 9.2 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RTA1 PF04479.13 ETS73333.1 - 2.2e-63 213.6 17.2 2.2e-63 213.6 17.2 1.4 2 0 0 2 2 2 1 RTA1 like protein Tannase PF07519.11 ETS73334.1 - 1.3e-89 301.3 1.2 1.7e-89 300.9 1.2 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 ETS73334.1 - 7.8e-05 22.2 0.1 0.011 15.2 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ETS73334.1 - 0.0055 16.0 0.0 0.52 9.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Tannase PF07519.11 ETS73335.1 - 6e-89 299.1 0.1 6.8e-89 298.9 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 ETS73335.1 - 0.00022 20.8 0.0 0.16 11.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ETS73335.1 - 0.0004 19.7 0.0 0.28 10.4 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS73335.1 - 0.0044 16.7 0.0 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold p450 PF00067.22 ETS73336.1 - 1.6e-67 228.2 0.0 2e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cu_bind_like PF02298.17 ETS73337.1 - 0.0011 19.0 0.1 0.0025 17.8 0.1 1.6 1 1 0 1 1 1 1 Plastocyanin-like domain Bmp PF02608.14 ETS73337.1 - 0.18 10.8 0.1 0.23 10.4 0.1 1.2 1 0 0 1 1 1 0 ABC transporter substrate-binding protein PnrA-like COesterase PF00135.28 ETS73338.1 - 4.7e-16 58.8 0.0 4.7e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS73338.1 - 0.00045 20.1 0.0 0.0023 17.8 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Tannase PF07519.11 ETS73339.1 - 4.5e-131 438.0 5.7 5.2e-131 437.8 5.7 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Alpha-L-AF_C PF06964.12 ETS73340.1 - 1.4e-18 67.6 0.0 2.8e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain DUF2220 PF09983.9 ETS73340.1 - 0.14 11.6 0.8 0.24 10.8 0.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) Sugar_tr PF00083.24 ETS73341.1 - 3.3e-95 319.6 21.5 3.8e-95 319.4 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS73341.1 - 6e-23 81.3 25.8 6e-23 81.3 25.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SR-25 PF10500.9 ETS73342.1 - 0.087 12.4 7.7 0.17 11.5 7.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Melibiase PF02065.18 ETS73344.1 - 3.1e-133 444.0 0.0 3.8e-133 443.7 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 ETS73344.1 - 4e-75 252.7 0.0 7.2e-75 251.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 ETS73344.1 - 1.7e-20 73.3 0.0 3.5e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 ETS73344.1 - 1.4e-05 24.3 0.1 2.2e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 SART-1 PF03343.13 ETS73345.1 - 4.9e-181 603.5 67.7 6e-181 603.2 67.7 1.1 1 0 0 1 1 1 1 SART-1 family Glyco_hydro_15 PF00723.21 ETS73346.1 - 3e-101 339.4 0.4 3.9e-101 339.0 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 ETS73346.1 - 1.4e-33 114.7 0.8 3.9e-33 113.2 0.8 1.8 1 0 0 1 1 1 1 Starch binding domain SAP130_C PF16014.5 ETS73346.1 - 7.4 5.6 8.4 11 5.0 8.4 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus CPT PF07931.12 ETS73347.1 - 0.00033 20.6 0.0 0.0007 19.5 0.0 1.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein PRK PF00485.18 ETS73347.1 - 0.00046 20.0 0.0 0.032 14.0 0.0 2.2 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 ETS73347.1 - 0.0088 16.6 0.0 0.018 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ETS73347.1 - 0.021 15.1 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ETS73347.1 - 0.031 14.7 0.0 0.055 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Fructosamin_kin PF03881.14 ETS73348.1 - 5.6e-75 252.2 0.0 5.9e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 ETS73348.1 - 5.2e-07 29.8 0.0 7.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ETS73348.1 - 0.22 10.8 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase ATP-grasp_2 PF08442.10 ETS73350.1 - 3.8e-77 258.4 0.4 3.8e-77 258.4 0.4 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 ETS73350.1 - 1.1e-26 93.5 0.4 2e-26 92.7 0.4 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 ETS73350.1 - 6.7e-08 32.3 0.1 2e-07 30.7 0.1 1.8 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 ETS73350.1 - 0.00043 20.1 1.4 0.0059 16.4 0.2 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PALP PF00291.25 ETS73350.1 - 0.073 12.5 0.3 0.39 10.1 0.0 2.2 3 0 0 3 3 3 0 Pyridoxal-phosphate dependent enzyme OKR_DC_1_N PF03709.15 ETS73350.1 - 0.11 12.8 0.1 0.86 9.9 0.0 2.5 3 1 0 3 3 3 0 Orn/Lys/Arg decarboxylase, N-terminal domain Zn_clus PF00172.18 ETS73351.1 - 2.9e-05 24.1 9.4 2.9e-05 24.1 9.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PMC2NT PF08066.12 ETS73351.1 - 0.16 12.7 1.6 3 8.6 0.0 3.0 3 0 0 3 3 3 0 PMC2NT (NUC016) domain DUF3112 PF11309.8 ETS73352.1 - 8.8e-11 41.7 13.2 4.9e-06 26.1 0.1 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) DUF2062 PF09835.9 ETS73352.1 - 0.023 14.5 3.3 0.055 13.3 3.3 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF805 PF05656.14 ETS73352.1 - 4.1 7.9 12.3 7.5 7.0 8.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF805) HXXEE PF13787.6 ETS73353.1 - 1.1e-23 84.1 19.3 2.1e-12 47.8 0.6 4.3 3 1 0 3 3 3 2 Protein of unknown function with HXXEE motif NmrA PF05368.13 ETS73354.1 - 1.7e-38 132.5 0.1 2.3e-38 132.1 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS73354.1 - 4.7e-14 52.7 0.0 5.8e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS73354.1 - 0.00013 21.5 0.0 0.00029 20.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ETS73354.1 - 0.0039 17.1 0.0 0.0061 16.5 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 ETS73354.1 - 0.004 16.6 0.0 0.006 16.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ETS73354.1 - 0.0049 15.9 0.0 0.0083 15.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ETS73354.1 - 0.0056 15.9 0.0 0.011 14.9 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 ETS73354.1 - 0.067 13.6 0.2 2.4 8.6 0.2 2.4 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 ETS73354.1 - 0.12 11.9 0.0 0.24 10.8 0.0 1.4 1 1 0 1 1 1 0 short chain dehydrogenase Fungal_trans PF04082.18 ETS73355.1 - 4.4e-16 58.7 2.5 8.6e-16 57.8 2.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2802 PF10975.8 ETS73355.1 - 0.087 13.0 0.9 15 5.8 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) Aldolase_II PF00596.21 ETS73356.1 - 1.6e-42 145.5 0.8 2.1e-42 145.1 0.8 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Ecl1 PF12855.7 ETS73357.1 - 3e-16 61.1 22.7 3.6e-16 60.8 22.7 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins HipA_C PF07804.12 ETS73357.1 - 0.078 12.7 0.1 0.093 12.4 0.1 1.2 1 0 0 1 1 1 0 HipA-like C-terminal domain NUDE_C PF04880.13 ETS73357.1 - 9.1 6.7 11.1 23 5.4 11.2 1.6 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region Cpn60_TCP1 PF00118.24 ETS73359.1 - 1.1e-173 578.4 1.5 1.2e-173 578.3 1.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BRK PF07533.16 ETS73359.1 - 0.037 13.6 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 BRK domain DUF1168 PF06658.12 ETS73360.1 - 1.8e-39 134.7 12.3 1.8e-39 134.7 12.3 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) DNA_pol3_a_NII PF11490.8 ETS73360.1 - 3.5 7.5 11.0 5.4 6.9 11.0 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II His_Phos_1 PF00300.22 ETS73361.1 - 8.6e-29 100.6 1.1 1.5e-28 99.9 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 ETS73361.1 - 0.033 13.6 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Zn_clus PF00172.18 ETS73363.1 - 0.00027 21.0 7.2 0.0005 20.1 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ETS73364.1 - 6.2e-28 97.7 66.7 1.7e-24 86.4 49.8 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS73364.1 - 1.5e-10 40.6 12.8 1.5e-10 40.6 12.8 2.9 2 1 0 3 3 3 1 Sugar (and other) transporter Aldo_ket_red PF00248.21 ETS73365.1 - 3.1e-73 246.5 0.0 3.5e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 ETS73366.1 - 3.4e-27 95.2 0.0 4.6e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS73366.1 - 1.2e-20 74.0 0.0 1.5e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS73366.1 - 2.8e-08 33.9 0.0 4.9e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS73366.1 - 0.026 14.0 0.0 0.11 11.9 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS73366.1 - 0.15 12.0 0.2 0.2 11.6 0.2 1.4 1 1 0 1 1 1 0 NAD(P)H-binding DUF1776 PF08643.10 ETS73366.1 - 0.23 10.8 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) PP-binding PF00550.25 ETS73367.1 - 3.8e-05 23.9 0.1 6.6e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 ETS73368.1 - 1.9e-23 83.3 0.1 2.8e-23 82.8 0.1 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.6 ETS73368.1 - 5.8e-13 50.1 0.0 1.2e-12 49.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ETS73368.1 - 2.3e-05 24.4 0.0 7.7e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 ETS73368.1 - 0.0057 16.1 0.1 0.009 15.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short PF00106.25 ETS73369.1 - 1.1e-20 74.0 0.0 1.4e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS73369.1 - 9.1e-14 51.6 0.0 1.1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS73369.1 - 3.7e-09 36.7 0.0 5e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS73369.1 - 0.0023 17.4 0.1 0.036 13.5 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family gp45-slide_C PF09116.10 ETS73370.1 - 0.055 13.5 0.0 3.3 7.8 0.0 2.2 2 0 0 2 2 2 0 gp45 sliding clamp, C terminal DUF3328 PF11807.8 ETS73371.1 - 1.3e-14 54.5 0.3 2.4e-14 53.6 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Acyl_transf_3 PF01757.22 ETS73372.1 - 9.3e-18 64.4 29.3 2.4e-17 63.0 29.3 1.6 1 1 0 1 1 1 1 Acyltransferase family DUF1624 PF07786.12 ETS73372.1 - 0.0024 17.5 9.5 0.0045 16.6 3.3 3.0 3 1 0 3 3 3 2 Protein of unknown function (DUF1624) Glyco_trans_2_3 PF13632.6 ETS73373.1 - 3.9e-12 46.5 4.1 3.9e-12 46.5 4.1 2.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ETS73373.1 - 1.6e-09 37.5 0.3 8.6e-09 35.1 0.3 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 ETS73373.1 - 1.4e-08 33.8 1.7 1.5e-07 30.5 1.7 2.2 1 1 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ETS73373.1 - 4.5e-08 33.3 0.4 7e-08 32.6 0.4 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Alpha-L-AF_C PF06964.12 ETS73375.1 - 8.5e-25 87.8 0.4 1.4e-24 87.1 0.4 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain p450 PF00067.22 ETS73376.1 - 2e-57 195.0 0.0 2.8e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 ETS73378.1 - 1e-05 24.5 0.4 1.7e-05 23.8 0.3 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Tyrosinase PF00264.20 ETS73379.1 - 1.8e-43 149.4 1.9 2.5e-43 148.9 1.9 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 ETS73379.1 - 2.1e-25 89.8 0.0 3.5e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Tyosinase C-terminal domain BatD PF13584.6 ETS73379.1 - 0.19 10.5 0.0 0.34 9.7 0.0 1.3 1 0 0 1 1 1 0 Oxygen tolerance p450 PF00067.22 ETS73381.1 - 3.1e-48 164.7 0.0 4.4e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GFA PF04828.14 ETS73383.1 - 4.1e-19 68.7 0.1 5.8e-19 68.2 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Peptidase_S8 PF00082.22 ETS73385.1 - 1.1e-11 44.6 2.0 5.3e-11 42.3 2.0 2.0 1 1 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 ETS73385.1 - 2.6e-05 24.7 0.2 0.014 15.9 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ETS73385.1 - 0.045 14.2 0.1 0.9 10.1 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 ETS73385.1 - 0.052 14.1 0.3 3.8 8.4 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeat Ank_2 PF12796.7 ETS73386.1 - 6.5e-104 340.7 4.3 9e-14 51.8 0.0 12.3 4 3 7 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS73386.1 - 5e-81 266.1 23.2 4.3e-08 33.5 0.0 18.0 9 4 10 19 19 19 17 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS73386.1 - 2.2e-75 247.7 23.6 2e-09 37.5 0.4 17.4 10 5 8 19 19 19 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS73386.1 - 1.6e-71 227.7 21.4 0.00084 19.6 0.0 23.2 25 0 0 25 25 25 16 Ankyrin repeat Ank PF00023.30 ETS73386.1 - 1e-61 202.8 37.7 1.4e-05 25.3 0.1 21.4 21 1 1 22 22 22 14 Ankyrin repeat ZZ PF00569.17 ETS73386.1 - 7.6e-05 22.4 5.9 0.00017 21.4 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type ABM PF03992.16 ETS73387.1 - 0.054 13.6 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Pectate_lyase_3 PF12708.7 ETS73390.1 - 7.1e-73 245.0 16.2 8.1e-68 228.5 6.5 3.0 3 0 0 3 3 3 2 Pectate lyase superfamily protein Acetyltransf_1 PF00583.25 ETS73391.1 - 5.7e-09 36.2 0.0 7.3e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS73391.1 - 2.7e-08 34.1 0.0 4.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS73391.1 - 5.1e-08 32.9 0.0 6.5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ETS73391.1 - 8.1e-07 29.3 0.0 9.5e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Na_Ca_ex PF01699.24 ETS73392.1 - 1.1e-18 67.7 7.0 1.3e-18 67.4 7.0 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein VCBS PF13517.6 ETS73393.1 - 1.4e-29 102.5 66.4 5.4e-10 39.7 6.0 8.6 4 3 5 9 9 9 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 ETS73393.1 - 4.3e-13 50.1 0.1 8.6e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS73393.1 - 7.6e-08 32.6 0.0 1.4e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 ETS73393.1 - 3.3e-06 26.6 17.5 0.094 12.1 0.1 7.2 6 2 0 8 8 8 3 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 ETS73393.1 - 4.9e-06 26.6 52.0 0.0026 17.8 1.3 8.0 8 0 0 8 8 8 4 FG-GAP repeat Lipase_GDSL_3 PF14606.6 ETS73393.1 - 0.0007 19.8 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Fungal_trans_2 PF11951.8 ETS73394.1 - 1.2e-11 44.1 0.0 1.8e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS73394.1 - 0.0015 18.7 1.1 0.0028 17.7 1.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tryp_inh PF17983.1 ETS73394.1 - 0.037 14.1 0.3 0.29 11.3 0.1 2.3 2 0 0 2 2 2 0 Trypsin inhibitors 1,2 and 3 Ank_4 PF13637.6 ETS73396.1 - 0.035 14.7 0.0 3.5 8.3 0.0 2.6 2 1 1 3 3 2 0 Ankyrin repeats (many copies) Ank PF00023.30 ETS73396.1 - 0.076 13.5 0.0 4.7 7.8 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 ETS73396.1 - 0.15 12.7 0.0 14 6.7 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat p450 PF00067.22 ETS73397.1 - 1.5e-20 73.4 0.1 1.9e-20 73.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS73398.1 - 1.5e-53 182.2 0.0 1.8e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS73399.1 - 5.3e-19 68.3 0.0 4.3e-17 62.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 ATG16 PF08614.11 ETS73400.1 - 1.1 9.5 5.2 1.8 8.7 5.2 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Ank_2 PF12796.7 ETS73401.1 - 1e-09 38.8 0.0 0.013 16.1 0.0 5.0 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS73401.1 - 3.7e-08 33.0 6.7 0.57 10.9 0.0 7.3 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.6 ETS73401.1 - 1.7e-06 28.4 0.4 5.2 7.8 0.0 6.1 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS73401.1 - 9.7e-06 25.8 0.9 2.8 8.4 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS73401.1 - 1.8e-05 25.0 11.8 2.5 8.7 0.0 6.9 8 0 0 8 8 8 2 Ankyrin repeat Pkinase PF00069.25 ETS73402.1 - 4.5e-27 95.1 0.0 7.1e-26 91.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS73402.1 - 1.7e-13 50.5 0.0 2.3e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 ETS73402.1 - 7.7e-05 21.6 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 ETS73402.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 ETS73402.1 - 0.076 12.3 0.3 0.53 9.5 0.0 2.0 2 0 0 2 2 2 0 Kinase-like FAP206 PF12018.8 ETS73403.1 - 0.098 12.2 0.4 0.16 11.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function HATPase_c PF02518.26 ETS73405.1 - 8.2e-21 74.6 0.1 1.8e-20 73.5 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ETS73405.1 - 6e-19 68.3 0.0 1.2e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ETS73405.1 - 2.6e-11 43.4 0.1 6.9e-11 42.0 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Glyco_hydro_cc PF11790.8 ETS73406.1 - 8.3e-48 163.0 1.3 1.4e-47 162.3 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Ecm33 PF12454.8 ETS73406.1 - 0.023 14.8 0.1 0.023 14.8 0.1 2.6 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Cellulase PF00150.18 ETS73406.1 - 0.053 12.9 0.2 0.16 11.4 0.1 1.8 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Hamartin PF04388.12 ETS73406.1 - 3.3 6.3 11.1 4.4 5.9 11.1 1.1 1 0 0 1 1 1 0 Hamartin protein DUF3341 PF11821.8 ETS73408.1 - 0.052 13.2 0.2 0.11 12.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Syndecan PF01034.20 ETS73408.1 - 0.19 11.6 5.9 1.7 8.6 1.4 2.8 2 0 0 2 2 2 0 Syndecan domain Cation_ATPase_C PF00689.21 ETS73408.1 - 0.23 11.1 8.6 0.45 10.2 8.6 1.6 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF3852 PF12963.7 ETS73408.1 - 5 7.5 10.7 7.3 7.0 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3852) zf-RING_2 PF13639.6 ETS73409.1 - 1.8e-12 47.3 4.1 2.9e-12 46.7 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ETS73409.1 - 6.4e-10 38.6 1.8 1.1e-09 37.8 1.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ETS73409.1 - 3.5e-07 30.0 4.2 5.4e-07 29.3 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ETS73409.1 - 9.3e-07 28.6 2.7 1.5e-06 28.0 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ETS73409.1 - 2.2e-06 27.8 4.8 5.9e-06 26.5 4.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 ETS73409.1 - 2.2e-05 24.2 3.8 3.8e-05 23.5 3.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ETS73409.1 - 8.3e-05 22.5 1.4 0.00013 21.8 1.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ETS73409.1 - 0.0018 18.3 0.7 0.0033 17.4 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 ETS73409.1 - 0.0049 16.7 1.2 0.0082 16.0 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS73409.1 - 0.0078 16.2 5.0 0.016 15.2 5.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 ETS73409.1 - 0.074 12.9 2.7 0.14 12.0 2.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 ETS73409.1 - 0.081 13.2 1.7 0.13 12.6 1.7 1.3 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 ETS73409.1 - 0.7 9.8 2.3 1.3 8.9 2.3 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 ETS73409.1 - 3.6 7.6 4.6 2.2 8.3 1.9 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 ETS73409.1 - 8.9 6.6 6.5 10 6.4 3.6 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain CAP_GLY PF01302.25 ETS73410.1 - 3.3e-21 75.1 1.3 5.2e-21 74.4 1.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 ETS73410.1 - 6.4e-21 74.6 0.0 9.8e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 ETS73410.1 - 0.0008 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Myb_DNA-binding PF00249.31 ETS73411.1 - 2.7e-11 43.5 0.7 6.7e-11 42.2 0.2 1.9 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ETS73411.1 - 5.4e-07 29.8 0.4 5.9e-06 26.4 0.3 2.3 1 1 1 2 2 2 1 Myb-like DNA-binding domain Takusan PF04822.13 ETS73411.1 - 0.058 13.3 0.0 0.084 12.8 0.0 1.4 1 1 0 1 1 1 0 Takusan Methyltransf_11 PF08241.12 ETS73413.1 - 2.5e-12 47.3 0.0 4.5e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS73413.1 - 8.2e-12 45.7 0.0 1.8e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS73413.1 - 1.6e-07 31.3 0.0 2.8e-07 30.5 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS73413.1 - 2.2e-06 28.3 0.0 4.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS73413.1 - 6.3e-06 26.1 0.0 8.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GFO_IDH_MocA PF01408.22 ETS73414.1 - 2.2e-17 64.0 0.3 3.3e-17 63.4 0.3 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 ETS73414.1 - 0.011 16.4 0.2 0.017 15.7 0.2 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Aldo_ket_red PF00248.21 ETS73415.1 - 1.2e-14 54.2 0.0 2.4e-13 50.0 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family CFIA_Pcf11 PF11526.8 ETS73416.1 - 1.3e-06 28.7 1.7 5.9e-06 26.7 1.7 2.0 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 ETS73416.1 - 0.00026 21.7 0.0 0.0052 17.6 0.0 3.1 4 0 0 4 4 4 1 RNA polymerase II-binding domain. VHS PF00790.19 ETS73416.1 - 0.0019 18.1 0.0 0.0065 16.3 0.0 1.8 2 0 0 2 2 2 1 VHS domain zf-C2H2_11 PF16622.5 ETS73416.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 ETS73416.1 - 0.18 11.8 4.2 0.19 11.6 0.8 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 ETS73416.1 - 0.18 12.7 5.0 2.9 9.0 0.5 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ETS73416.1 - 0.37 11.3 2.4 19 5.9 0.6 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type MgtE PF01769.16 ETS73417.1 - 0.71 10.3 8.5 0.97 9.8 0.1 2.1 2 0 0 2 2 2 0 Divalent cation transporter Cu_bind_like PF02298.17 ETS73418.1 - 0.0013 18.7 3.2 0.0023 17.9 0.2 2.6 2 1 0 2 2 2 1 Plastocyanin-like domain NST1 PF13945.6 ETS73418.1 - 0.26 11.3 6.8 0.43 10.7 6.8 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator SMN PF06003.12 ETS73419.1 - 3.2e-06 26.6 10.0 0.0002 20.7 2.1 2.1 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) RRM_1 PF00076.22 ETS73420.1 - 4e-17 61.8 0.0 1.1e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ETS73420.1 - 5.6e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ETS73420.1 - 0.2 11.7 0.2 0.4 10.7 0.2 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GRAB PF10375.9 ETS73421.1 - 4.7e-09 35.8 0.1 9.4e-09 34.8 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain CEP63 PF17045.5 ETS73421.1 - 0.00041 20.3 40.9 0.00041 20.3 40.9 2.2 1 1 2 3 3 3 1 Centrosomal protein of 63 kDa Spc7 PF08317.11 ETS73421.1 - 0.0029 16.5 28.1 0.0029 16.5 28.1 2.4 1 1 1 2 2 2 1 Spc7 kinetochore protein Nup54_57_C PF18570.1 ETS73421.1 - 0.0052 16.3 1.1 0.0052 16.3 1.1 4.5 5 0 0 5 5 5 1 NUP57/Nup54 C-terminal domain Filament PF00038.21 ETS73421.1 - 0.01 15.5 55.5 0.018 14.6 29.2 2.2 1 1 1 2 2 2 0 Intermediate filament protein BST2 PF16716.5 ETS73421.1 - 0.015 15.8 53.2 0.1 13.2 2.7 5.8 1 1 3 5 5 5 0 Bone marrow stromal antigen 2 NPV_P10 PF05531.12 ETS73421.1 - 0.3 11.6 23.0 0.076 13.5 1.1 5.0 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.8 ETS73421.1 - 0.39 8.2 58.3 0.78 7.2 37.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 ETS73421.1 - 0.63 10.1 67.1 0.075 13.1 10.7 4.4 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Lectin_N PF03954.14 ETS73421.1 - 0.63 9.8 26.3 0.34 10.7 2.1 3.5 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain HicB_lk_antitox PF15919.5 ETS73421.1 - 0.76 9.9 6.6 0.46 10.6 1.1 2.6 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system CENP-F_leu_zip PF10473.9 ETS73421.1 - 1.4 8.9 64.6 2.3 8.2 17.8 3.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 ETS73421.1 - 1.7 8.7 32.4 0.8 9.8 1.8 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 ETS73421.1 - 2.7 7.4 58.8 7.8 5.9 28.8 3.6 1 1 2 3 3 3 0 Golgin subfamily A member 5 MAD PF05557.13 ETS73421.1 - 2.9 6.1 59.1 1.2 7.4 31.2 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF4407 PF14362.6 ETS73421.1 - 4.8 6.4 50.8 5.9 6.2 17.7 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 ETS73421.1 - 6.3 6.8 18.4 1.2 9.2 2.5 3.7 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 ETS73421.1 - 9.3 5.5 59.1 1.2 8.5 13.2 4.0 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding CHD5 PF04420.14 ETS73423.1 - 2.5e-64 215.9 2.4 3.2e-64 215.6 2.4 1.1 1 0 0 1 1 1 1 CHD5-like protein FlxA PF14282.6 ETS73423.1 - 0.014 15.4 0.2 0.027 14.4 0.2 1.4 1 0 0 1 1 1 0 FlxA-like protein DUF1772 PF08592.11 ETS73423.1 - 0.048 14.0 0.2 0.048 14.0 0.2 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) TMEM247 PF15444.6 ETS73423.1 - 0.053 13.6 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 DUF1515 PF07439.11 ETS73423.1 - 0.059 13.4 0.6 0.11 12.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) PPTA PF01239.22 ETS73424.1 - 2.1e-09 36.8 13.5 0.00015 21.3 0.9 4.6 4 0 0 4 4 4 3 Protein prenyltransferase alpha subunit repeat Asp PF00026.23 ETS73425.1 - 3.4e-68 230.4 7.8 5.6e-68 229.7 7.8 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS73425.1 - 4.7e-11 43.2 2.6 4.7e-11 43.2 2.6 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal BAAT_C PF08840.11 ETS73425.1 - 0.0034 17.3 0.7 3.1 7.7 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal TAXi_C PF14541.6 ETS73425.1 - 0.028 14.2 0.1 0.076 12.8 0.0 1.8 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 ETS73425.1 - 0.057 14.0 0.0 0.39 11.3 0.0 2.6 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease Na_H_Exchanger PF00999.21 ETS73426.1 - 4.3e-30 104.8 36.9 1.9e-24 86.2 24.5 3.1 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family SLAC1 PF03595.17 ETS73427.1 - 6.8e-74 249.0 45.8 8.3e-74 248.7 45.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TMEM132D_C PF15706.5 ETS73427.1 - 0.091 12.5 2.0 0.26 11.1 2.0 1.8 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Spo7 PF03907.13 ETS73427.1 - 0.2 11.1 0.9 0.61 9.5 0.9 1.8 1 0 0 1 1 1 0 Spo7-like protein PP2C PF00481.21 ETS73428.1 - 7.3e-35 120.8 0.0 2e-29 103.0 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 ETS73428.1 - 0.0099 15.5 0.2 0.047 13.3 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C HET PF06985.11 ETS73429.1 - 4.5e-27 95.2 0.0 9.7e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MEKHLA PF08670.11 ETS73429.1 - 0.023 14.6 0.3 1.2 9.0 0.0 2.7 3 0 0 3 3 3 0 MEKHLA domain Peptidase_S41 PF03572.18 ETS73430.1 - 8.5e-09 35.2 0.0 3.6e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 Peptidase family S41 NACHT PF05729.12 ETS73431.1 - 5e-06 26.5 0.0 1.5e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ETS73431.1 - 7.5e-05 23.0 0.0 0.00016 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ETS73431.1 - 0.00091 19.4 0.0 0.0022 18.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 ETS73431.1 - 0.0012 18.9 0.0 0.33 11.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 ETS73431.1 - 0.0015 17.7 0.1 0.0039 16.4 0.1 1.7 1 1 0 1 1 1 1 NB-ARC domain AAA PF00004.29 ETS73431.1 - 0.0037 17.7 0.0 0.0092 16.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS73431.1 - 0.0056 17.1 0.0 0.018 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 ETS73431.1 - 0.0076 16.5 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ETS73431.1 - 0.0082 16.6 0.3 0.02 15.4 0.3 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETS73431.1 - 0.028 15.0 0.0 0.074 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 ETS73431.1 - 0.03 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 NTPase_1 PF03266.15 ETS73431.1 - 0.033 14.1 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.6 ETS73431.1 - 0.038 14.3 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ETS73431.1 - 0.048 14.2 0.0 0.16 12.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 ETS73431.1 - 0.065 13.6 0.0 0.19 12.1 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Zeta_toxin PF06414.12 ETS73431.1 - 0.07 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin BC10 PF06726.12 ETS73432.1 - 2e-16 60.0 11.0 3.1e-16 59.3 11.0 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DUF4802 PF16060.5 ETS73432.1 - 0.65 10.2 4.7 2.9 8.1 4.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4802) LPP PF04728.13 ETS73433.1 - 0.035 14.5 8.0 0.095 13.1 0.4 4.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Ge1_WD40 PF16529.5 ETS73433.1 - 0.09 11.7 0.0 0.39 9.6 0.0 1.8 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF445 PF04286.12 ETS73433.1 - 0.76 9.5 23.8 0.18 11.6 12.4 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF445) DivIC PF04977.15 ETS73433.1 - 9.1 6.1 7.3 28 4.6 1.3 2.9 2 0 0 2 2 2 0 Septum formation initiator DIM PF08194.12 ETS73434.1 - 0.99 9.7 4.5 3.6 7.9 0.5 3.3 2 0 0 2 2 2 0 DIM protein KRTAP PF11759.8 ETS73436.1 - 0.28 11.7 3.1 0.3 11.7 0.5 2.0 2 0 0 2 2 2 0 Keratin-associated matrix Zn_clus PF00172.18 ETS73437.1 - 7.5e-05 22.8 15.2 0.00013 22.0 15.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF829 PF05705.14 ETS73438.1 - 5.2e-40 137.9 0.0 6.3e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Lumazine_bd_2 PF12893.7 ETS73439.1 - 2.8e-22 79.6 0.1 3.2e-22 79.4 0.1 1.0 1 0 0 1 1 1 1 Putative lumazine-binding DUF4878 PF12870.7 ETS73439.1 - 0.053 13.8 0.1 0.083 13.2 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4878) DUF3828 PF12883.7 ETS73439.1 - 0.11 12.9 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) ADH_N PF08240.12 ETS73440.1 - 4.3e-21 74.8 0.0 8.3e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS73440.1 - 2.5e-12 46.9 0.0 4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ETS73440.1 - 0.17 11.2 0.2 0.27 10.6 0.2 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.16 ETS73441.1 - 8.1e-30 103.9 32.2 1.1e-29 103.5 32.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS73441.1 - 0.32 10.2 17.9 1.7 7.8 17.9 2.0 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB TssN PF17555.2 ETS73441.1 - 0.94 8.8 7.8 0.056 12.8 1.7 1.9 2 0 0 2 2 2 0 Type VI secretion system, TssN GATase PF00117.28 ETS73442.1 - 3.8e-10 39.8 0.0 5.3e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I HTS PF04204.16 ETS73442.1 - 1.2e-05 24.4 0.0 1.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Homoserine O-succinyltransferase Peptidase_C26 PF07722.13 ETS73442.1 - 0.013 15.2 0.9 0.062 13.1 0.9 2.2 1 1 0 1 1 1 0 Peptidase C26 Zn_clus PF00172.18 ETS73443.1 - 3e-09 36.8 10.1 6.8e-09 35.7 10.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS73443.1 - 0.00013 21.1 1.1 0.00022 20.3 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.11 ETS73444.1 - 2.9e-10 40.7 0.0 1.3e-09 38.6 0.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 ETS73445.1 - 3.5e-27 95.1 0.1 1.2e-19 70.5 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS73445.1 - 6.6e-17 61.9 0.0 2.1e-15 56.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS73445.1 - 2.2e-06 27.7 0.0 3.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS73445.1 - 0.00034 20.1 0.1 0.0018 17.8 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS73445.1 - 0.00037 20.0 0.0 0.018 14.4 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ETS73445.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding p450 PF00067.22 ETS73447.1 - 3.7e-56 190.8 0.0 4.6e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 ETS73448.1 - 2.7e-18 66.1 0.0 4e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS73448.1 - 9.7e-15 54.7 0.0 1.3e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ETS73448.1 - 0.024 14.1 0.0 0.23 10.9 0.0 2.4 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS73448.1 - 0.092 12.1 0.0 0.48 9.8 0.0 2.3 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase FAD_binding_4 PF01565.23 ETS73449.1 - 1e-22 80.4 0.7 2e-22 79.4 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS73449.1 - 6.1e-10 39.0 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 ETS73449.1 - 0.022 14.1 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Abhydrolase_6 PF12697.7 ETS73450.1 - 6e-10 40.1 0.0 8e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS73450.1 - 6.2e-08 32.2 0.0 1.1e-07 31.4 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 ETS73450.1 - 3.7e-07 30.0 0.0 4.6e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 ETS73450.1 - 2.4e-06 27.2 0.1 0.0043 16.5 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ETS73450.1 - 1.1e-05 25.3 0.1 3.2e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 ETS73450.1 - 2e-05 23.4 0.0 3.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 ETS73450.1 - 0.0017 18.3 0.0 0.0057 16.6 0.0 1.7 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 ETS73450.1 - 0.0038 16.8 0.0 0.0095 15.5 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF1100 PF06500.11 ETS73450.1 - 0.0066 15.3 0.0 0.019 13.8 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) ketoacyl-synt PF00109.26 ETS73451.1 - 2.6e-68 230.4 0.1 4.8e-68 229.5 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 ETS73451.1 - 9.9e-58 195.7 0.0 1.9e-57 194.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 ETS73451.1 - 2.5e-52 177.4 0.1 4.6e-52 176.5 0.1 1.5 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 ETS73451.1 - 7.2e-44 150.6 0.0 1.3e-43 149.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ETS73451.1 - 2.5e-34 117.8 0.8 2.2e-33 114.8 0.2 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ETS73451.1 - 2.9e-20 72.8 0.0 8.1e-20 71.4 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 ETS73451.1 - 1.7e-17 64.7 0.0 5.7e-17 63.0 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ETS73451.1 - 8.7e-16 58.1 0.0 2e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 ETS73451.1 - 1e-07 32.2 0.0 3.1e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 ETS73451.1 - 1.3e-06 28.2 0.0 3.3e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 ETS73451.1 - 6.5e-06 25.7 0.6 1.9e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 ETS73451.1 - 1.3e-05 24.7 0.1 0.0014 18.1 0.1 2.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain SAT PF16073.5 ETS73451.1 - 0.0027 17.5 0.0 0.05 13.3 0.0 2.4 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis DUF1652 PF07865.11 ETS73451.1 - 0.029 14.2 0.0 0.36 10.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) Peptidase_M28 PF04389.17 ETS73452.1 - 6.6e-30 104.3 0.5 1e-29 103.6 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ETS73452.1 - 2e-05 24.4 0.1 4e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Methyltransf_2 PF00891.18 ETS73453.1 - 7.9e-15 54.7 0.0 1.2e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 ETS73453.1 - 0.00011 22.1 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain HTH_IclR PF09339.10 ETS73453.1 - 0.072 12.9 1.3 0.19 11.6 0.2 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain Rrf2 PF02082.20 ETS73453.1 - 0.08 13.3 0.1 0.22 11.9 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulator HTH_5 PF01022.20 ETS73453.1 - 0.15 11.9 1.1 0.41 10.6 0.3 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family MarR_2 PF12802.7 ETS73453.1 - 0.16 11.8 2.3 0.18 11.7 0.2 2.2 3 0 0 3 3 3 0 MarR family Dimerisation PF08100.11 ETS73453.1 - 0.47 10.5 3.5 0.6 10.2 1.0 2.4 2 0 0 2 2 2 0 Dimerisation domain DUF5367 PF17329.2 ETS73454.1 - 0.26 11.4 2.5 0.39 10.9 2.2 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5367) Mac PF12464.8 ETS73455.1 - 5e-05 23.5 0.0 6.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase HAD_SAK_1 PF10307.9 ETS73456.1 - 5.4e-77 258.2 0.0 8.2e-77 257.6 0.0 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Bac_chlorC PF02043.17 ETS73456.1 - 0.041 13.9 0.2 0.15 12.1 0.2 1.9 1 0 0 1 1 1 0 Bacteriochlorophyll C binding protein MFS_1 PF07690.16 ETS73457.1 - 3e-34 118.5 41.8 4.2e-34 118.0 37.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS73457.1 - 1e-07 31.2 10.7 1e-07 31.2 10.7 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter NB-ARC PF00931.22 ETS73458.1 - 2.6e-06 26.8 0.0 4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 ETS73458.1 - 2.4e-05 24.8 0.0 6.5e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.14 ETS73458.1 - 0.0049 16.4 0.0 0.0097 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Sa_NUDIX PF18167.1 ETS73458.1 - 0.15 11.9 0.2 0.28 11.0 0.2 1.4 1 0 0 1 1 1 0 SMODS-associated NUDIX domain FHA PF00498.26 ETS73459.1 - 1.9e-15 56.9 0.0 3.6e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ETS73459.1 - 0.0048 17.2 0.0 0.17 12.2 0.0 2.3 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain MFS_1 PF07690.16 ETS73462.1 - 1e-30 106.9 53.1 1.2e-21 77.0 29.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS73462.1 - 0.19 10.5 25.9 0.053 12.4 9.9 3.3 2 2 0 2 2 2 0 MFS_1 like family OPT PF03169.15 ETS73463.1 - 1.7e-155 519.1 53.4 2e-155 518.9 53.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.6 ETS73463.1 - 0.11 11.9 1.3 0.46 9.8 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF2427 PF10348.9 ETS73463.1 - 5.8 6.8 9.9 0.1 12.4 1.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) DNA_primase_S PF01896.19 ETS73464.1 - 3.9e-64 215.9 0.6 5.2e-64 215.5 0.6 1.2 1 0 0 1 1 1 1 DNA primase small subunit Tyrosinase PF00264.20 ETS73465.1 - 4.3e-53 180.9 0.2 5.7e-53 180.5 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase CP2 PF04516.15 ETS73466.1 - 1.5e-80 269.8 0.0 2.4e-80 269.1 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.14 ETS73466.1 - 0.046 12.5 0.0 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 Tektin family AKNA PF12443.8 ETS73466.1 - 0.14 12.9 0.7 0.36 11.5 0.7 1.7 1 0 0 1 1 1 0 AT-hook-containing transcription factor IMP2_C PF18591.1 ETS73466.1 - 0.15 12.0 0.0 0.43 10.5 0.0 1.7 1 0 0 1 1 1 0 Immune Mapped Protein 2 (IMP2) C-terminal domain TMF_DNA_bd PF12329.8 ETS73466.1 - 0.3 11.1 0.9 0.66 10.0 0.9 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SAP PF02037.27 ETS73467.1 - 6.9e-08 32.1 0.9 0.0013 18.4 0.1 2.9 2 0 0 2 2 2 2 SAP domain Endonuc-dimeris PF09124.10 ETS73467.1 - 0.0039 17.3 0.1 0.011 15.9 0.1 1.7 1 0 0 1 1 1 1 T4 recombination endonuclease VII, dimerisation TORC_M PF12885.7 ETS73467.1 - 0.75 9.7 5.6 1.6 8.6 0.1 2.7 3 0 0 3 3 3 0 Transducer of regulated CREB activity middle domain Oxysterol_BP PF01237.18 ETS73468.1 - 3.5e-53 180.8 0.0 5e-51 173.7 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein U1snRNP70_N PF12220.8 ETS73468.1 - 0.31 11.7 2.4 6.4 7.5 0.8 2.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal UDPGT PF00201.18 ETS73469.1 - 3.5e-07 29.4 0.0 1.2e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 ETS73469.1 - 0.004 17.2 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 ETS73469.1 - 0.02 14.9 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain XPG_I PF00867.18 ETS73470.1 - 1.5e-17 63.7 0.0 2.7e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 ETS73470.1 - 9e-05 22.9 0.0 0.00023 21.6 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 ETS73470.1 - 0.015 14.8 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing Epimerase PF01370.21 ETS73471.1 - 1.5e-15 57.3 0.0 2.3e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ETS73471.1 - 9.5e-10 38.1 0.0 2.4e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 ETS73471.1 - 1.3e-09 38.0 0.0 3.6e-09 36.5 0.0 1.8 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ETS73471.1 - 8.7e-09 34.8 0.0 1.1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ETS73471.1 - 1.5e-07 31.5 0.4 2.9e-07 30.5 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 ETS73471.1 - 1.2e-05 25.3 0.5 0.00016 21.6 0.5 2.1 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 ETS73471.1 - 1.7e-05 24.5 0.1 6.2e-05 22.7 0.2 1.8 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 ETS73471.1 - 0.00096 18.7 0.0 0.006 16.1 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 ETS73471.1 - 0.0032 16.7 0.0 0.029 13.5 0.0 2.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Glyco_hydro_36 PF17167.4 ETS73472.1 - 2.6e-61 207.6 0.1 4.7e-61 206.8 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_transf_36 PF06165.11 ETS73472.1 - 3.8e-27 95.3 0.0 7.6e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 36 Bac_rhamnosid6H PF17389.2 ETS73472.1 - 0.00054 19.3 0.4 0.0011 18.3 0.4 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain HSP9_HSP12 PF04119.12 ETS73473.1 - 0.072 13.5 3.6 2 8.9 0.6 2.3 1 1 1 2 2 2 0 Heat shock protein 9/12 eIF2A PF08662.11 ETS73474.1 - 1.8e-80 269.4 0.1 1.2e-78 263.4 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 ETS73474.1 - 4.6e-06 27.3 0.4 3.8 8.5 0.1 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS73474.1 - 0.029 14.7 0.0 5.8 7.3 0.0 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 ETS73474.1 - 0.51 10.3 1.9 28 4.8 0.1 4.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Amino_oxidase PF01593.24 ETS73476.1 - 6.3e-18 65.3 0.0 9e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 ETS73476.1 - 6.5e-11 42.4 0.0 4.8e-07 29.7 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS73476.1 - 3e-10 40.2 0.1 7.8e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS73476.1 - 5.4e-08 32.4 0.0 5e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS73476.1 - 0.00024 21.6 0.0 0.044 14.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS73476.1 - 0.011 14.9 0.0 0.035 13.3 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ETS73476.1 - 0.022 14.8 0.2 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 ETS73476.1 - 0.039 13.2 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 ETS73476.1 - 0.18 11.1 0.1 0.31 10.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase MCRA PF06100.11 ETS73476.1 - 0.19 10.4 0.0 0.3 9.8 0.0 1.3 1 0 0 1 1 1 0 MCRA family C166 PF17615.2 ETS73477.1 - 0.00024 21.3 0.6 0.00073 19.7 0.1 2.1 2 0 0 2 2 2 1 Family of unknown function Helitron_like_N PF14214.6 ETS73479.1 - 1.2e-32 113.7 0.3 1.2e-32 113.7 0.3 2.4 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus FANCI_S2 PF14676.6 ETS73479.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 FANCI solenoid 2 DUF2717 PF10911.8 ETS73480.1 - 0.073 12.8 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2717) Drc1-Sld2 PF11719.8 ETS73481.1 - 1.7e-87 294.9 28.1 3.1e-87 294.0 28.1 1.4 1 1 0 1 1 1 1 DNA replication and checkpoint protein zf-RING_2 PF13639.6 ETS73482.1 - 3e-08 33.9 11.8 5.1e-08 33.1 11.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ETS73482.1 - 6.9e-06 25.8 8.1 1.2e-05 25.1 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ETS73482.1 - 1.3e-05 24.9 12.0 2.3e-05 24.1 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS73482.1 - 2.7e-05 23.9 9.1 4.2e-05 23.3 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ETS73482.1 - 0.00073 19.8 11.1 0.0028 17.9 11.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain p450 PF00067.22 ETS73483.1 - 2.5e-53 181.5 0.0 3.1e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 JAB PF01398.21 ETS73484.1 - 1.1e-14 54.4 0.0 2e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 ETS73484.1 - 0.00041 20.5 0.2 0.00088 19.4 0.2 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 ETS73484.1 - 0.00063 19.5 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain V-ATPase_G_2 PF16999.5 ETS73484.1 - 2.8 8.4 8.7 0.9 10.0 1.5 2.3 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Prefoldin_2 PF01920.20 ETS73485.1 - 2.9e-22 78.6 17.7 3.4e-22 78.4 17.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 ETS73485.1 - 0.00045 20.1 1.7 0.00045 20.1 1.7 2.5 2 1 1 3 3 3 1 Prefoldin subunit Spc7 PF08317.11 ETS73485.1 - 0.00087 18.3 14.0 0.001 18.1 14.0 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein Prefoldin_3 PF13758.6 ETS73485.1 - 0.0011 19.0 7.0 0.0015 18.5 7.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit KH_5 PF13184.6 ETS73485.1 - 0.026 14.6 0.6 0.057 13.5 0.6 1.6 1 0 0 1 1 1 0 NusA-like KH domain MREG PF15812.5 ETS73485.1 - 0.028 14.7 1.3 0.047 14.0 1.3 1.7 1 1 0 1 1 1 0 Melanoregulin FliD_C PF07195.12 ETS73485.1 - 0.03 13.7 7.7 0.046 13.2 7.7 1.3 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus GAS PF13851.6 ETS73485.1 - 0.04 13.3 18.1 0.4 10.0 18.1 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Rx_N PF18052.1 ETS73485.1 - 0.061 13.6 8.0 0.94 9.8 3.7 2.4 2 0 0 2 2 2 0 Rx N-terminal domain PHM7_cyt PF14703.6 ETS73485.1 - 0.07 13.4 10.1 0.13 12.5 10.1 1.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Golgin_A5 PF09787.9 ETS73485.1 - 0.088 12.3 12.2 0.1 12.0 12.2 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Nup88 PF10168.9 ETS73485.1 - 0.12 10.2 13.0 0.13 10.1 13.0 1.0 1 0 0 1 1 1 0 Nuclear pore component DivIC PF04977.15 ETS73485.1 - 0.13 12.1 19.5 0.95 9.3 6.2 3.2 2 1 1 3 3 3 0 Septum formation initiator DUF4201 PF13870.6 ETS73485.1 - 0.18 11.5 12.9 0.64 9.7 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.8 ETS73485.1 - 0.19 11.9 10.0 0.18 12.0 3.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CSN5_C PF18323.1 ETS73485.1 - 0.24 12.3 9.4 0.17 12.8 1.5 2.2 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Bcr-Abl_Oligo PF09036.10 ETS73485.1 - 0.25 11.4 3.6 0.69 10.0 0.3 2.2 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain TPR_MLP1_2 PF07926.12 ETS73485.1 - 0.31 11.1 15.1 1.3 9.0 7.3 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF948 PF06103.11 ETS73485.1 - 0.37 11.1 5.3 5.8 7.2 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4164 PF13747.6 ETS73485.1 - 0.37 11.1 6.8 0.23 11.8 1.8 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) FlaC_arch PF05377.11 ETS73485.1 - 0.49 10.8 10.6 6.3 7.3 1.1 3.4 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 ETS73485.1 - 0.52 10.6 15.2 0.76 10.1 1.6 3.0 2 1 0 3 3 3 0 ABC transporter C-terminal domain DUF5082 PF16888.5 ETS73485.1 - 0.6 10.4 12.3 0.95 9.8 12.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) ETRAMP PF09716.10 ETS73485.1 - 0.82 9.8 5.1 1.1 9.4 5.0 1.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) MIP-T3_C PF17749.1 ETS73485.1 - 0.85 9.6 15.1 11 5.9 15.1 2.1 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Com_YlbF PF06133.11 ETS73485.1 - 0.88 10.2 17.3 0.4 11.3 8.2 2.2 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA DHR10 PF18595.1 ETS73485.1 - 0.89 9.6 16.1 2.4 8.2 6.1 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain NPV_P10 PF05531.12 ETS73485.1 - 1.4 9.5 9.9 2.9 8.4 3.8 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Uso1_p115_C PF04871.13 ETS73485.1 - 1.4 9.3 16.8 0.47 10.8 7.5 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Tropomyosin_1 PF12718.7 ETS73485.1 - 1.5 9.0 16.5 1.8 8.7 2.3 2.2 2 0 0 2 2 2 0 Tropomyosin like BRE1 PF08647.11 ETS73485.1 - 1.6 8.8 15.2 1 9.5 1.8 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase MtrG PF04210.13 ETS73485.1 - 1.8 8.5 4.0 3.3 7.6 1.9 2.3 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Seryl_tRNA_N PF02403.22 ETS73485.1 - 1.9 8.8 15.3 15 5.8 13.6 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain YgaB PF14182.6 ETS73485.1 - 2 8.8 14.6 0.54 10.7 3.9 2.7 2 1 1 3 3 3 0 YgaB-like protein DUF1192 PF06698.11 ETS73485.1 - 2.6 8.2 10.0 4.9 7.3 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Cob_adeno_trans PF01923.18 ETS73485.1 - 3.1 7.9 6.8 25 5.0 6.8 1.9 1 1 0 1 1 1 0 Cobalamin adenosyltransferase APG6_N PF17675.1 ETS73485.1 - 3.2 8.3 19.8 11 6.6 10.4 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region JIP_LZII PF16471.5 ETS73485.1 - 3.2 8.0 11.7 0.61 10.3 1.5 3.0 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II DUF4407 PF14362.6 ETS73485.1 - 3.8 6.8 13.1 11 5.3 13.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SKA2 PF16740.5 ETS73485.1 - 4.3 7.2 12.0 1.1 9.1 4.8 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 ZapB PF06005.12 ETS73485.1 - 5 7.6 16.8 1.8 9.1 9.1 2.2 2 0 0 2 2 2 0 Cell division protein ZapB Spc24 PF08286.11 ETS73485.1 - 5.8 7.2 14.2 7.5 6.8 5.0 2.1 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.10 ETS73485.1 - 7 6.8 12.5 1.8e+02 2.3 12.5 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 ETS73485.1 - 7.1 7.2 15.5 4.5 7.8 9.0 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF2203 PF09969.9 ETS73485.1 - 7.3 7.3 10.9 43 4.9 10.6 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) TMPIT PF07851.13 ETS73485.1 - 7.7 5.7 10.3 12 5.1 10.3 1.4 1 1 0 1 1 1 0 TMPIT-like protein K-box PF01486.17 ETS73485.1 - 8.3 6.7 14.0 2.5 8.3 4.5 2.2 1 1 0 2 2 2 0 K-box region AAA PF00004.29 ETS73486.1 - 1.7e-42 145.0 0.0 2.8e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 ETS73486.1 - 1.7e-27 95.2 0.1 5.1e-27 93.6 0.1 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 ETS73486.1 - 4.1e-23 81.2 1.7 1.1e-22 79.8 1.7 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 ETS73486.1 - 2.6e-06 27.1 0.0 1.6e-05 24.6 0.0 2.4 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 ETS73486.1 - 1.6e-05 24.7 0.0 3.2e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ETS73486.1 - 1.7e-05 25.2 0.1 0.00021 21.7 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 ETS73486.1 - 4.4e-05 22.9 0.0 7.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 ETS73486.1 - 4.6e-05 23.4 0.0 0.00027 20.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ETS73486.1 - 4.8e-05 23.7 0.1 0.011 16.1 0.0 2.9 3 0 0 3 3 2 1 RNA helicase IstB_IS21 PF01695.17 ETS73486.1 - 0.00012 21.8 0.0 0.00028 20.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 ETS73486.1 - 0.00021 21.6 0.1 0.021 15.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 ETS73486.1 - 0.00027 21.0 0.0 0.00062 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 ETS73486.1 - 0.00056 19.2 0.0 0.001 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 ETS73486.1 - 0.00056 20.1 0.0 0.0029 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ETS73486.1 - 0.0011 19.1 0.0 0.0035 17.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETS73486.1 - 0.0014 19.2 0.2 0.006 17.1 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.6 ETS73486.1 - 0.0022 17.6 0.2 0.5 9.9 0.1 2.9 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 ETS73486.1 - 0.0023 17.7 0.0 0.0082 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 ETS73486.1 - 0.016 15.6 0.0 0.055 13.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 ETS73486.1 - 0.017 14.7 0.1 0.096 12.2 0.0 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 ETS73486.1 - 0.032 13.6 0.0 0.086 12.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 ETS73486.1 - 0.036 14.0 0.0 0.39 10.6 0.0 2.1 1 1 1 2 2 2 0 NACHT domain ATPase PF06745.13 ETS73486.1 - 0.051 12.9 0.0 7 5.9 0.0 2.4 1 1 1 2 2 2 0 KaiC Parvo_NS1 PF01057.17 ETS73486.1 - 0.055 12.6 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 ETS73486.1 - 0.08 12.4 0.1 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.11 ETS73486.1 - 0.081 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Torsin Cytidylate_kin PF02224.18 ETS73486.1 - 0.14 11.8 0.3 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Cytidylate kinase Sigma54_activat PF00158.26 ETS73486.1 - 0.15 11.7 0.0 0.41 10.3 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain 3Beta_HSD PF01073.19 ETS73488.1 - 0.0026 16.8 0.0 0.0038 16.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3Beta_HSD PF01073.19 ETS73489.1 - 3.6e-16 59.0 0.0 3.1e-15 56.0 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ETS73489.1 - 7.4e-10 38.4 0.0 1.9e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.21 ETS73489.1 - 4.7e-09 36.1 0.0 1e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ETS73489.1 - 0.00051 19.3 0.0 0.00095 18.4 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ETS73489.1 - 0.0015 18.5 0.0 0.0047 16.8 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 ETS73489.1 - 0.0022 17.9 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 ETS73489.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 ETS73490.1 - 1.9e-28 99.4 30.8 1.9e-28 99.4 30.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS73490.1 - 9.2e-10 37.9 12.1 9.2e-10 37.9 12.1 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter NmrA PF05368.13 ETS73491.1 - 1.4e-17 64.1 0.0 1.8e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS73491.1 - 4.1e-11 43.1 0.0 8.4e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS73491.1 - 0.0055 16.2 0.0 0.056 12.9 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family AP_endonuc_2 PF01261.24 ETS73491.1 - 0.0084 15.6 0.0 0.014 14.9 0.0 1.5 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel SID PF11778.8 ETS73491.1 - 0.092 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Septation initiation TGS PF02824.21 ETS73491.1 - 0.15 12.1 0.0 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 TGS domain MFS_1 PF07690.16 ETS73492.1 - 1.6e-16 60.2 12.7 2.1e-16 59.8 12.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CBM_2 PF00553.19 ETS73492.1 - 0.0092 16.3 0.4 0.02 15.2 0.4 1.5 1 0 0 1 1 1 1 Cellulose binding domain FSH1 PF03959.13 ETS73493.1 - 2.2e-34 119.0 0.0 2.9e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 ETS73493.1 - 1.5e-06 28.2 0.0 2.3e-05 24.3 0.0 2.2 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 ETS73493.1 - 0.0063 17.1 0.0 0.011 16.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS73493.1 - 0.19 11.3 0.0 0.54 9.9 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Fringe PF02434.16 ETS73494.1 - 8.6e-06 25.4 0.6 0.0051 16.3 0.7 3.1 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.6 ETS73494.1 - 0.00098 19.0 1.8 0.0024 17.7 1.8 1.6 1 0 0 1 1 1 1 PAN domain Porin_OmpL1 PF11389.8 ETS73494.1 - 0.14 11.4 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 Leptospira porin protein OmpL1 Hva1_TUDOR PF11160.8 ETS73495.1 - 2.7e-15 56.3 2.5 2.7e-15 56.3 2.5 2.8 2 1 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain Glyco_hydro_106 PF17132.4 ETS73496.1 - 6.8e-32 110.6 0.3 1.8e-24 86.1 0.0 2.1 1 1 0 2 2 2 2 alpha-L-rhamnosidase DLH PF01738.18 ETS73497.1 - 3.1e-27 95.5 0.0 3.9e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ETS73497.1 - 3.2e-05 23.7 0.0 0.0003 20.5 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 ETS73497.1 - 0.0083 16.1 0.0 0.79 9.6 0.0 2.1 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 ETS73497.1 - 0.011 16.3 0.1 0.014 16.0 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ETS73497.1 - 0.058 13.2 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family 3Beta_HSD PF01073.19 ETS73498.1 - 1.5e-15 57.0 0.0 2.6e-15 56.2 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ETS73498.1 - 1.3e-13 51.0 0.0 2e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ETS73498.1 - 4.3e-13 49.0 0.0 8e-07 28.5 0.0 2.3 2 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 ETS73498.1 - 1.9e-12 47.5 0.0 3.8e-12 46.5 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ETS73498.1 - 2.7e-08 33.6 0.0 4.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ETS73498.1 - 4.3e-06 26.0 0.1 7.9e-06 25.2 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ETS73498.1 - 1.2e-05 24.7 0.0 1.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 ETS73498.1 - 0.00012 21.6 0.2 0.0029 17.1 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.10 ETS73498.1 - 0.0013 18.7 0.3 0.003 17.5 0.3 1.6 1 1 0 1 1 1 1 KR domain COG5 PF10392.9 ETS73498.1 - 0.032 14.4 0.1 0.066 13.4 0.1 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 NmrA PF05368.13 ETS73498.1 - 0.052 13.1 0.1 0.11 12.1 0.1 1.7 1 1 0 1 1 1 0 NmrA-like family YAcAr PF10686.9 ETS73498.1 - 0.061 13.3 0.1 0.42 10.6 0.1 2.3 1 1 0 1 1 1 0 YspA, cpYpsA-related SLOG family Glyco_hydro_47 PF01532.20 ETS73499.1 - 7.6e-184 611.9 0.4 7.6e-184 611.9 0.4 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 Fig1 PF12351.8 ETS73500.1 - 2e-57 194.2 4.2 2e-57 194.2 4.2 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 DUF898 PF05987.13 ETS73500.1 - 0.041 12.9 13.4 0.087 11.9 13.0 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF2207 PF09972.9 ETS73500.1 - 0.7 8.6 14.9 0.17 10.7 0.1 2.1 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Pkinase PF00069.25 ETS73501.1 - 3.1e-27 95.6 0.0 4.1e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS73501.1 - 3.1e-05 23.4 0.0 6.4e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ETS73501.1 - 0.0011 17.9 0.1 0.0014 17.4 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ETS73501.1 - 0.044 13.7 3.0 0.26 11.2 1.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 ETS73501.1 - 0.049 13.0 1.2 0.061 12.7 0.2 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ParD PF09386.10 ETS73501.1 - 0.08 13.3 0.0 0.27 11.6 0.0 1.9 1 1 1 2 2 2 0 Antitoxin ParD p450 PF00067.22 ETS73502.1 - 1.6e-29 103.0 0.0 2.1e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TRI12 PF06609.13 ETS73502.1 - 0.027 12.9 0.0 0.045 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF4771 PF15995.5 ETS73502.1 - 0.17 12.2 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) polyprenyl_synt PF00348.17 ETS73503.1 - 2.4e-73 246.4 0.0 3.7e-73 245.8 0.0 1.3 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 ETS73503.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Vma12 PF11712.8 ETS73504.1 - 2.2e-40 137.9 0.0 6.8e-40 136.4 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase XK-related PF09815.9 ETS73504.1 - 0.0091 15.1 0.2 0.016 14.3 0.2 1.4 1 0 0 1 1 1 1 XK-related protein zf-C2H2_3 PF13878.6 ETS73505.1 - 3.8e-11 42.6 1.2 8.3e-11 41.5 1.2 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Sec62 PF03839.16 ETS73505.1 - 8.5 5.8 7.9 4.6 6.7 5.2 1.9 2 0 0 2 2 2 0 Translocation protein Sec62 Peroxidase_2 PF01328.17 ETS73506.1 - 1.3e-40 140.0 0.0 1.6e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 CFEM PF05730.11 ETS73507.1 - 1.1e-11 44.7 7.2 2.2e-11 43.7 7.2 1.5 1 0 0 1 1 1 1 CFEM domain GMC_oxred_N PF00732.19 ETS73508.1 - 3.3e-27 95.6 0.0 1.4e-16 60.7 0.0 3.2 2 1 1 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS73508.1 - 6.9e-24 85.0 0.3 1.3e-23 84.1 0.0 1.6 2 0 0 2 2 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 ETS73508.1 - 4e-07 29.6 0.0 1.6e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS73508.1 - 0.00023 21.3 0.9 0.0012 19.1 0.9 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS73508.1 - 0.0022 17.3 0.0 0.3 10.3 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ETS73508.1 - 0.0052 16.4 0.3 0.017 14.8 0.2 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 ETS73508.1 - 0.022 13.8 1.1 0.034 13.2 0.6 1.5 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 ETS73508.1 - 0.053 13.1 0.1 0.78 9.3 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 ETS73508.1 - 0.075 12.6 0.9 2.9 7.4 1.9 2.8 3 1 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ETS73508.1 - 0.086 11.9 0.3 0.13 11.3 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 ETS73508.1 - 0.15 11.3 0.2 0.22 10.7 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 ETS73508.1 - 0.21 10.3 0.1 0.37 9.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein GST_N PF02798.20 ETS73509.1 - 1.6e-16 60.4 0.0 2.3e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ETS73509.1 - 8e-14 51.8 0.0 1.6e-13 50.9 0.0 1.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ETS73509.1 - 5.2e-12 45.9 0.0 6.8e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_5 PF18485.1 ETS73509.1 - 0.025 14.9 0.0 0.045 14.1 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain FAD_binding_3 PF01494.19 ETS73510.1 - 2.9e-65 220.8 0.0 3.6e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.18 ETS73511.1 - 3.7e-07 30.1 10.1 6.6e-07 29.4 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_92 PF07971.12 ETS73512.1 - 5.7e-142 473.9 0.0 9.5e-141 469.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 ETS73512.1 - 4.2e-62 210.1 0.1 7e-62 209.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain O-FucT PF10250.9 ETS73513.1 - 5.6e-12 46.0 0.0 2.9e-11 43.7 0.0 2.2 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Amidohydro_1 PF01979.20 ETS73514.1 - 4.2e-26 92.1 0.0 2.4e-25 89.6 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS73514.1 - 1.4e-12 47.9 0.0 4.5e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family AalphaY_MDB PF04611.12 ETS73514.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region DUF3425 PF11905.8 ETS73515.1 - 1.6e-22 79.8 0.0 3.5e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_Maf PF03131.17 ETS73515.1 - 0.015 15.8 2.5 0.028 14.9 2.5 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor adh_short PF00106.25 ETS73516.1 - 5.5e-22 78.2 0.2 1.3e-17 64.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS73516.1 - 1.3e-11 44.5 0.1 2e-07 30.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS73516.1 - 6.6e-05 22.9 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS73516.1 - 0.081 12.4 0.1 0.21 11.0 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MIP PF00230.20 ETS73517.1 - 1e-46 159.5 14.8 1.5e-46 159.0 14.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein ETRAMP PF09716.10 ETS73517.1 - 0.053 13.6 0.0 20 5.3 0.1 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PDR_assoc PF08370.11 ETS73517.1 - 0.14 11.9 2.2 0.94 9.3 0.1 2.8 3 0 0 3 3 3 0 Plant PDR ABC transporter associated MFS_1 PF07690.16 ETS73518.1 - 8.5e-44 149.9 36.0 8.5e-44 149.9 36.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS73518.1 - 2.4e-16 59.6 4.8 2.4e-16 59.6 4.8 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 ETS73518.1 - 5.8e-05 22.5 0.9 5.8e-05 22.5 0.9 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 ETS73518.1 - 0.00012 20.7 1.0 0.00019 20.0 1.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ABC_tran PF00005.27 ETS73519.1 - 2.3e-49 167.5 0.1 2.8e-23 83.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 ETS73519.1 - 5.7e-45 153.3 32.4 1.9e-28 99.3 5.8 2.6 3 0 0 3 3 2 2 ABC-2 type transporter AAA_21 PF13304.6 ETS73519.1 - 9.8e-12 45.3 8.1 0.0036 17.1 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETS73519.1 - 7.3e-09 35.4 1.9 0.0081 15.6 0.1 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ETS73519.1 - 3.3e-08 34.1 3.4 0.0026 18.2 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ETS73519.1 - 1.2e-07 31.8 0.8 0.0078 16.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 ETS73519.1 - 1.7e-07 32.0 0.4 0.027 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 ETS73519.1 - 2.1e-06 27.5 0.8 0.063 12.8 0.0 3.1 4 0 0 4 4 3 2 AAA domain NACHT PF05729.12 ETS73519.1 - 2.2e-06 27.7 0.2 0.011 15.7 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.6 ETS73519.1 - 8.3e-06 25.5 3.1 0.046 13.5 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 ETS73519.1 - 1.6e-05 24.7 0.1 0.046 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 ETS73519.1 - 1.7e-05 25.1 0.4 0.22 11.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 ETS73519.1 - 0.00012 21.3 0.2 0.42 9.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_28 PF13521.6 ETS73519.1 - 0.00019 21.7 0.6 0.069 13.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 ETS73519.1 - 0.00031 20.4 1.8 0.26 10.8 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 ETS73519.1 - 0.00042 20.7 0.3 0.085 13.2 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 ETS73519.1 - 0.00093 19.6 0.1 0.066 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ETS73519.1 - 0.0026 17.5 0.4 2.2 8.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ETS73519.1 - 0.0026 18.1 0.2 2.6 8.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_15 PF13175.6 ETS73519.1 - 0.0031 17.3 1.9 1.7 8.3 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 ETS73519.1 - 0.0033 17.4 1.2 2.6 8.0 0.1 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ETS73519.1 - 0.0033 18.0 0.1 5 7.7 0.0 3.1 4 0 0 4 4 2 0 AAA domain ATPase_2 PF01637.18 ETS73519.1 - 0.0049 16.8 0.1 1.8 8.4 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea SbcCD_C PF13558.6 ETS73519.1 - 0.0055 16.9 0.6 13 6.1 0.1 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 ETS73519.1 - 0.0093 16.4 0.1 6.1 7.3 0.0 3.3 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 ETS73519.1 - 0.014 15.6 1.1 2.8 8.2 0.2 2.8 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 ETS73519.1 - 0.015 15.5 0.4 4.9 7.3 0.1 2.8 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 ETS73519.1 - 0.037 13.8 2.2 8.1 6.1 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 ETS73519.1 - 0.041 13.2 2.9 2.2 7.6 0.4 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 ETS73519.1 - 0.049 13.7 2.9 1.8 8.6 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_ATPase PF09818.9 ETS73519.1 - 0.095 11.5 0.7 0.27 10.0 0.1 1.9 3 0 0 3 3 2 0 Predicted ATPase of the ABC class MobB PF03205.14 ETS73519.1 - 0.11 12.4 0.3 8.5 6.3 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.16 ETS73519.1 - 0.13 11.7 0.3 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 ETS73519.1 - 0.13 11.6 0.3 3 7.1 0.1 2.7 3 0 0 3 3 3 0 KaiC IstB_IS21 PF01695.17 ETS73519.1 - 0.14 11.9 0.1 29 4.3 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein PduV-EutP PF10662.9 ETS73519.1 - 0.16 11.7 0.3 22 4.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 ETS73519.1 - 0.18 11.3 0.3 5.5 6.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region PRK PF00485.18 ETS73519.1 - 0.18 11.5 1.1 4.8 6.9 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Pox_A32 PF04665.12 ETS73519.1 - 0.19 11.2 4.2 3.1 7.2 0.5 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein Septin PF00735.18 ETS73519.1 - 0.19 11.0 1.3 12 5.1 0.1 2.2 2 0 0 2 2 2 0 Septin Sigma54_activat PF00158.26 ETS73519.1 - 0.2 11.4 0.1 18 5.0 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF2075 PF09848.9 ETS73519.1 - 0.21 10.8 0.6 13 4.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 ETS73519.1 - 0.21 11.5 0.4 12 5.7 0.1 3.2 4 0 0 4 4 4 0 NTPase G-alpha PF00503.20 ETS73519.1 - 0.25 10.4 0.1 13 4.8 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Cytidylate_kin PF02224.18 ETS73519.1 - 0.37 10.5 1.3 4.4 7.0 0.1 2.3 2 0 0 2 2 2 0 Cytidylate kinase AAA_11 PF13086.6 ETS73519.1 - 1 9.1 3.4 8.9 6.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain SPATA3 PF15662.5 ETS73519.1 - 2 9.0 7.7 3.6 8.2 7.7 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Ank_2 PF12796.7 ETS73521.1 - 1.3e-10 41.8 0.0 7.7e-08 32.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS73521.1 - 1.6e-05 25.1 0.1 0.37 11.2 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS73521.1 - 1.8e-05 24.7 0.2 0.51 11.1 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 ETS73521.1 - 0.00034 21.1 0.6 2.6 8.7 0.0 4.1 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS73521.1 - 0.0032 17.8 0.2 3.8 8.1 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat DUF3447 PF11929.8 ETS73521.1 - 0.0081 16.1 0.0 0.27 11.2 0.0 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) ADH_N PF08240.12 ETS73522.1 - 8.5e-25 86.8 2.5 1.7e-24 85.8 2.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS73522.1 - 5.6e-17 61.9 0.0 8.5e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS73522.1 - 1.3e-07 31.3 0.1 9.6e-06 25.2 0.0 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 ETS73522.1 - 0.029 13.6 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ETS73522.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain adh_short_C2 PF13561.6 ETS73523.1 - 4.3e-60 203.2 2.9 4.8e-60 203.0 2.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS73523.1 - 8.2e-52 175.5 3.5 1e-51 175.2 3.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS73523.1 - 1e-17 64.6 0.9 1.3e-17 64.2 0.9 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS73523.1 - 6.4e-05 22.5 1.2 0.0002 20.9 1.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS73523.1 - 0.16 11.3 0.0 12 5.2 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Fungal_trans PF04082.18 ETS73524.1 - 1.9e-20 73.0 0.2 2.9e-20 72.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 ETS73525.1 - 6.6e-93 312.0 21.7 8.1e-93 311.7 21.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS73525.1 - 2.3e-14 53.1 55.1 1.8e-13 50.1 33.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DJ-1_PfpI PF01965.24 ETS73526.1 - 1.2e-08 34.9 0.0 3.7e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ETS73526.1 - 0.0019 17.9 0.0 0.0074 16.0 0.0 1.9 1 1 0 1 1 1 1 ThiJ/PfpI family-like APH PF01636.23 ETS73527.1 - 4.3e-09 36.7 0.0 8.4e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family AcylCoA_dehyd_C PF12186.8 ETS73527.1 - 0.021 14.9 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal K_oxygenase PF13434.6 ETS73528.1 - 2.1e-12 46.9 0.0 6e-12 45.4 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ETS73528.1 - 2.9e-10 39.9 0.0 2.2e-09 37.0 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ETS73528.1 - 3.2e-08 32.5 0.0 1.1e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ETS73528.1 - 7.9e-06 25.3 0.0 0.0011 18.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_1 PF00583.25 ETS73529.1 - 2.1e-05 24.7 0.0 3.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4291 PF14124.6 ETS73529.1 - 0.067 13.1 0.2 0.096 12.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4291) Fungal_trans_2 PF11951.8 ETS73530.1 - 4.9e-31 107.9 0.1 3.2e-30 105.2 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS73530.1 - 1.5e-08 34.6 12.0 2.6e-08 33.8 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2059 PF09832.9 ETS73530.1 - 0.056 13.5 0.1 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) AT_hook PF02178.19 ETS73530.1 - 0.089 12.7 4.7 0.23 11.4 4.7 1.8 1 0 0 1 1 1 0 AT hook motif ADH_N_2 PF16884.5 ETS73531.1 - 4e-33 113.5 0.0 9.9e-33 112.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 ETS73531.1 - 1.4e-16 60.7 0.0 2.3e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS73531.1 - 3.1e-07 31.5 0.0 6.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PhoH PF02562.16 ETS73531.1 - 0.098 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Myb_DNA-bind_6 PF13921.6 ETS73532.1 - 3.5e-13 49.6 1.8 5.5e-07 29.7 0.1 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ETS73532.1 - 5.2e-13 49.0 3.5 1.9e-05 24.8 1.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 ETS73532.1 - 0.00045 20.5 0.4 0.0031 17.9 0.4 2.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain FMO-like PF00743.19 ETS73533.1 - 1.4e-43 149.1 0.0 4.9e-22 78.1 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ETS73533.1 - 6.8e-15 55.1 0.0 4.2e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS73533.1 - 3.5e-12 46.2 0.2 4.1e-08 32.8 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS73533.1 - 7e-08 32.0 1.6 8.8e-06 25.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ETS73533.1 - 7.9e-08 32.4 0.4 5.1e-07 29.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS73533.1 - 8.4e-08 32.2 0.0 4.6e-05 23.2 0.0 3.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS73533.1 - 1.2e-06 28.6 1.9 3.6e-05 23.8 0.3 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 ETS73533.1 - 1.4e-06 27.9 0.0 0.0005 19.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 ETS73533.1 - 3.8e-05 24.2 2.5 0.0018 18.8 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS73533.1 - 0.00025 20.4 0.1 0.00089 18.6 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 ETS73533.1 - 0.0031 16.9 0.6 0.023 14.1 0.1 2.3 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ETS73533.1 - 0.0075 15.6 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 ETS73533.1 - 0.0077 15.6 0.4 1.2 8.4 0.3 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 ETS73533.1 - 0.015 15.4 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 ETS73533.1 - 0.022 13.8 0.1 0.048 12.7 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 ETS73533.1 - 0.046 12.4 0.2 0.083 11.6 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 ETS73533.1 - 0.066 12.3 0.0 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A TraO PF10626.9 ETS73533.1 - 0.18 11.5 0.1 0.43 10.3 0.1 1.5 1 0 0 1 1 1 0 Conjugative transposon protein TraO MFS_1 PF07690.16 ETS73534.1 - 4.6e-16 58.7 20.8 2.9e-13 49.5 8.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CHD5 PF04420.14 ETS73534.1 - 0.23 11.3 1.8 0.26 11.1 0.3 1.9 2 1 0 2 2 2 0 CHD5-like protein MFS_1 PF07690.16 ETS73535.1 - 0.01 14.8 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily TauD PF02668.16 ETS73536.1 - 5.8e-60 203.4 0.5 7e-60 203.1 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family peroxidase PF00141.23 ETS73537.1 - 7.8e-22 78.1 0.1 1.1e-21 77.6 0.1 1.2 1 0 0 1 1 1 1 Peroxidase PSI_PSAK PF01241.18 ETS73537.1 - 0.018 15.0 0.1 7.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Photosystem I psaG / psaK Glyco_hydro_61 PF03443.14 ETS73538.1 - 4e-63 213.1 0.1 4e-63 213.1 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Beta_helix PF13229.6 ETS73538.1 - 0.022 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Right handed beta helix region Methyltransf_25 PF13649.6 ETS73539.1 - 1.6e-12 47.9 0.0 2.9e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS73539.1 - 2.9e-09 37.4 0.0 4.9e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS73539.1 - 1.1e-07 31.8 0.0 1.4e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS73539.1 - 1.9e-07 31.0 0.0 3.2e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS73539.1 - 1.1e-05 24.9 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ETS73539.1 - 0.00024 21.8 0.0 0.0004 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ETS73539.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 ETS73539.1 - 0.034 14.1 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 ETS73539.1 - 0.04 13.0 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.14 ETS73539.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.19 ETS73539.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 ETS73539.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase tRNA_U5-meth_tr PF05958.11 ETS73539.1 - 0.18 10.8 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltr_RsmB-F PF01189.17 ETS73539.1 - 0.23 11.1 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_9 PF08003.11 ETS73539.1 - 0.24 10.3 0.0 0.4 9.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) ELYS PF13934.6 ETS73540.1 - 6.3e-63 212.7 0.0 7.4e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.19 ETS73541.1 - 1.3e-71 240.6 21.8 7.1e-71 238.1 21.8 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ETS73541.1 - 5.9e-24 84.6 0.0 2.6e-23 82.5 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 ETS73541.1 - 1.9e-12 47.7 0.0 6.5e-05 22.9 0.0 3.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ETS73541.1 - 3.8e-08 33.5 6.3 3.8e-08 33.5 6.3 4.7 2 2 2 4 4 2 1 AAA ATPase domain Tektin PF03148.14 ETS73541.1 - 2.4e-05 23.3 19.4 2.4e-05 23.3 19.4 6.6 3 2 4 7 7 7 2 Tektin family DUF4201 PF13870.6 ETS73541.1 - 0.0006 19.6 16.7 0.0006 19.6 16.7 8.6 4 2 4 8 8 8 3 Domain of unknown function (DUF4201) AAA_29 PF13555.6 ETS73541.1 - 0.00086 19.0 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Laminin_II PF06009.12 ETS73541.1 - 0.0013 18.8 2.2 0.0013 18.8 2.2 9.2 3 2 5 9 9 9 1 Laminin Domain II DivIC PF04977.15 ETS73541.1 - 0.0039 16.9 5.7 0.0039 16.9 5.7 12.2 6 4 7 13 13 13 1 Septum formation initiator DASH_Dam1 PF08653.10 ETS73541.1 - 1.5 8.7 6.4 1.1e+02 2.7 0.2 5.4 3 2 2 5 5 5 0 DASH complex subunit Dam1 ABC_tran PF00005.27 ETS73541.1 - 1.6 9.2 0.0 1.6 9.2 0.0 6.5 4 3 0 4 4 2 0 ABC transporter DUF948 PF06103.11 ETS73541.1 - 2 8.8 34.0 0.86 9.9 0.9 6.4 5 1 1 6 6 6 0 Bacterial protein of unknown function (DUF948) Beta-lactamase PF00144.24 ETS73544.1 - 2.3e-59 201.3 0.3 2.8e-59 201.0 0.3 1.0 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_3_C PF01915.22 ETS73546.1 - 2.1e-45 155.2 0.1 3.2e-45 154.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS73546.1 - 5.2e-31 108.2 0.0 1.6e-30 106.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS73546.1 - 1.9e-21 75.9 0.0 3.7e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_61 PF03443.14 ETS73547.1 - 6.3e-55 186.3 1.4 7.4e-55 186.1 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_7 PF00840.20 ETS73548.1 - 1.8e-84 284.0 23.1 5.2e-29 101.2 2.2 5.0 1 1 3 4 4 4 4 Glycosyl hydrolase family 7 DUF1772 PF08592.11 ETS73549.1 - 0.37 11.1 6.4 0.12 12.7 3.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF4267 PF14087.6 ETS73550.1 - 2.2e-17 63.1 4.0 2.8e-17 62.8 4.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) PX PF00787.24 ETS73551.1 - 2.9e-16 59.4 0.0 5.2e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 PX domain T3SSipB PF16535.5 ETS73551.1 - 0.0016 18.9 4.4 0.0016 18.9 4.4 2.1 2 1 0 2 2 2 1 Type III cell invasion protein SipB Spc29 PF17082.5 ETS73551.1 - 0.3 10.9 5.8 0.71 9.7 5.8 1.6 1 0 0 1 1 1 0 Spindle Pole Component 29 GMC_oxred_N PF00732.19 ETS73552.1 - 1.9e-60 204.8 0.0 2.4e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS73552.1 - 1e-30 107.2 0.1 1.6e-30 106.5 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 ETS73552.1 - 0.0086 15.3 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 ETS73552.1 - 0.012 14.7 0.0 0.054 12.5 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 ETS73552.1 - 0.09 13.0 0.0 0.31 11.3 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ETS73552.1 - 0.13 11.4 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_25 PF13649.6 ETS73553.1 - 1.1e-08 35.6 0.0 2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS73553.1 - 1.2e-07 32.2 0.0 2.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS73553.1 - 4.7e-05 24.0 0.0 8.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS73553.1 - 0.058 13.2 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Oxidored_FMN PF00724.20 ETS73554.1 - 2.1e-43 148.9 0.0 2.7e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 ETS73554.1 - 2e-07 30.4 0.0 3.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NMO PF03060.15 ETS73554.1 - 0.015 14.7 0.1 0.034 13.5 0.0 1.6 1 1 0 1 1 1 0 Nitronate monooxygenase AP_endonuc_2 PF01261.24 ETS73554.1 - 0.027 13.9 0.0 2 7.8 0.0 2.5 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel Trp_syntA PF00290.20 ETS73554.1 - 0.052 12.4 0.0 0.12 11.2 0.0 1.6 1 1 0 1 1 1 0 Tryptophan synthase alpha chain Fungal_trans PF04082.18 ETS73556.1 - 1.8e-09 37.0 0.2 3.6e-09 36.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS73556.1 - 1.6e-08 34.5 10.7 2.6e-08 33.9 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ETS73557.1 - 6.1e-14 51.7 36.3 6.1e-14 51.7 36.3 2.1 2 1 1 3 3 3 1 Major Facilitator Superfamily Innexin PF00876.18 ETS73557.1 - 0.092 12.0 0.1 0.19 11.0 0.1 1.4 1 1 0 1 1 1 0 Innexin NPCC PF08058.11 ETS73557.1 - 0.32 11.1 1.6 0.75 9.9 1.6 1.6 1 0 0 1 1 1 0 Nuclear pore complex component p450 PF00067.22 ETS73558.1 - 1.5e-50 172.3 0.0 2.8e-50 171.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 SKG6 PF08693.10 ETS73559.1 - 1.1e-11 43.9 1.0 1.1e-11 43.9 1.0 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 ETS73559.1 - 0.0015 18.5 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family VSP PF03302.13 ETS73559.1 - 0.0016 17.4 1.6 0.0022 17.0 1.6 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Mid2 PF04478.12 ETS73559.1 - 0.015 15.1 0.2 0.029 14.2 0.2 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MGC-24 PF05283.11 ETS73559.1 - 0.016 15.6 4.6 0.036 14.5 4.6 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RIFIN PF02009.16 ETS73559.1 - 0.039 13.9 0.0 0.049 13.5 0.0 1.1 1 0 0 1 1 1 0 Rifin FixS PF03597.15 ETS73559.1 - 0.14 11.9 1.1 0.25 11.1 1.1 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type FSA_C PF10479.9 ETS73559.1 - 1.1 7.2 7.1 1.4 7.0 7.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SSP160 PF06933.11 ETS73559.1 - 2 6.5 21.3 2.7 6.1 21.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Gram_pos_anchor PF00746.21 ETS73559.1 - 4.9 7.2 6.2 3.8 7.5 0.3 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Gly_transf_sug PF04488.15 ETS73560.1 - 6.5e-11 42.7 0.0 1.4e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ETS73560.1 - 0.00024 20.6 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein K_channel_TID PF07941.11 ETS73560.1 - 0.62 10.6 2.1 1.3 9.5 2.1 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain PAN_2 PF08276.11 ETS73561.1 - 8.7e-05 22.6 5.5 0.39 10.8 0.1 3.5 3 0 0 3 3 3 2 PAN-like domain PAN_4 PF14295.6 ETS73561.1 - 0.00011 22.0 9.4 0.4 10.6 0.2 3.7 3 0 0 3 3 3 3 PAN domain F-box-like PF12937.7 ETS73562.1 - 7.7e-05 22.5 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS73562.1 - 0.038 13.9 0.0 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 F-box domain AA_permease_2 PF13520.6 ETS73563.1 - 6.3e-47 160.4 53.6 7.9e-47 160.0 53.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS73563.1 - 4.6e-29 101.3 49.2 6e-29 101.0 49.2 1.0 1 0 0 1 1 1 1 Amino acid permease KleE PF17394.2 ETS73563.1 - 7.4 6.8 14.2 0.62 10.3 4.4 2.9 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein DUF3810 PF12725.7 ETS73564.1 - 0.22 10.8 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) CN_hydrolase PF00795.22 ETS73565.1 - 4.3e-32 111.5 0.0 6.2e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 ETS73565.1 - 5.9e-24 84.5 0.0 1.6e-23 83.1 0.0 1.7 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 ETS73565.1 - 0.064 12.9 0.0 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Asparagine synthase Glyco_hydro_3_C PF01915.22 ETS73566.1 - 4.4e-49 167.2 0.0 1e-48 166.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS73566.1 - 3.2e-36 125.3 0.0 5.8e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS73566.1 - 5e-15 55.4 0.0 9.1e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain HET PF06985.11 ETS73567.1 - 3.2e-34 118.4 0.0 5.2e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LMBR1 PF04791.16 ETS73570.1 - 0.001 18.1 0.0 0.0014 17.6 0.0 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Mitofilin PF09731.9 ETS73570.1 - 6.2 5.5 42.4 9.6 4.9 42.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FTA2 PF13095.6 ETS73571.1 - 8.5e-42 143.2 0.0 1.5e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 NAD_binding_10 PF13460.6 ETS73572.1 - 4.4e-09 36.5 0.0 5.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS73572.1 - 1.1e-07 31.6 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ETS73572.1 - 0.00022 20.8 0.0 0.00034 20.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS73572.1 - 0.009 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ETS73572.1 - 0.011 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein T3SS_ExsE PF18286.1 ETS73572.1 - 0.11 12.5 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 Type III secretion system ExsE adh_short PF00106.25 ETS73573.1 - 1e-18 67.5 0.0 1.4e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS73573.1 - 2.3e-13 50.2 0.0 3e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 ETS73573.1 - 0.00059 19.3 0.0 0.0025 17.3 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ETS73573.1 - 0.0042 16.6 0.0 0.02 14.4 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS73573.1 - 0.015 15.2 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Glyco_hydro_1 PF00232.18 ETS73574.1 - 3.3e-138 460.9 1.8 4.2e-138 460.6 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF3632 PF12311.8 ETS73575.1 - 0.00064 20.2 0.1 0.00089 19.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Fringe PF02434.16 ETS73576.1 - 0.00024 20.6 0.5 0.0025 17.3 0.5 2.1 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 ETS73576.1 - 0.0082 16.0 0.1 0.033 14.0 0.0 2.0 1 1 1 2 2 2 1 Galactosyltransferase PAN_4 PF14295.6 ETS73576.1 - 0.023 14.6 1.3 0.051 13.5 1.3 1.6 1 0 0 1 1 1 0 PAN domain PAP2_3 PF14378.6 ETS73578.1 - 1.1e-22 80.6 22.3 9.3e-18 64.6 2.6 2.7 3 0 0 3 3 3 2 PAP2 superfamily PAP2_C PF14360.6 ETS73578.1 - 0.011 16.2 0.4 0.011 16.2 0.4 3.2 4 0 0 4 4 4 0 PAP2 superfamily C-terminal RtcB PF01139.17 ETS73578.1 - 0.064 12.4 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB PhoR PF11808.8 ETS73578.1 - 0.068 13.6 2.6 0.21 12.0 2.6 1.9 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR DUF3328 PF11807.8 ETS73579.1 - 8.7e-19 68.2 4.5 2.2e-18 66.8 4.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Lipase_2 PF01674.18 ETS73579.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) APH PF01636.23 ETS73580.1 - 2.2e-17 63.8 0.0 4.9e-17 62.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETS73580.1 - 0.0023 17.6 0.1 0.0038 16.8 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF5310 PF17237.2 ETS73581.1 - 0.054 13.4 0.9 0.093 12.6 0.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5310) Macoilin PF09726.9 ETS73581.1 - 0.34 9.4 1.9 0.46 9.0 1.9 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 ETS73581.1 - 0.36 10.0 8.4 0.085 12.0 5.3 1.4 2 0 0 2 2 2 0 RAM signalling pathway protein p450 PF00067.22 ETS73583.1 - 8.2e-52 176.5 0.0 1.1e-51 176.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3433 PF11915.8 ETS73584.1 - 4.5e-28 97.5 18.0 7.2e-17 61.6 3.2 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Rax2 PF12768.7 ETS73584.1 - 0.01 15.3 2.7 1.2 8.5 0.0 2.5 2 0 0 2 2 2 2 Cortical protein marker for cell polarity Nha1_C PF08619.10 ETS73585.1 - 1.4e-120 403.7 50.0 6.8e-120 401.4 50.0 1.8 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 ETS73585.1 - 3e-76 256.7 21.1 3.6e-76 256.4 21.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Colicin_E5 PF12106.8 ETS73585.1 - 0.008 16.5 1.8 0.34 11.2 0.1 2.6 2 0 0 2 2 2 1 Colicin E5 ribonuclease domain Tom22 PF04281.13 ETS73586.1 - 1.2e-51 174.1 0.2 1.4e-51 173.9 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Mur_ligase_M PF08245.12 ETS73586.1 - 0.028 14.4 0.1 0.039 14.0 0.1 1.2 1 0 0 1 1 1 0 Mur ligase middle domain Pectate_lyase_3 PF12708.7 ETS73587.1 - 5.3e-35 121.2 5.2 2.6e-26 92.8 1.4 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein FAD_binding_4 PF01565.23 ETS73588.1 - 7.7e-14 51.6 4.8 7.7e-14 51.6 4.8 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 ETS73588.1 - 0.00033 20.7 0.0 0.00072 19.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like YpmT PF17431.2 ETS73589.1 - 0.098 12.7 1.2 0.6 10.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized YmpT-like Methyltransf_31 PF13847.6 ETS73592.1 - 1.9e-07 31.0 0.0 4.4e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS73592.1 - 6e-07 30.1 0.0 1.4e-06 28.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS73592.1 - 1.8e-05 24.6 0.0 3.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS73592.1 - 0.001 19.6 0.0 0.0029 18.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS73592.1 - 0.0017 19.0 0.0 0.0088 16.8 0.0 2.2 3 1 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS73592.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 ETS73592.1 - 0.13 12.4 0.0 0.23 11.5 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase CheR PF01739.18 ETS73592.1 - 0.22 11.0 0.0 0.95 8.9 0.0 1.9 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain DUF4449 PF14613.6 ETS73594.1 - 2.6e-69 232.5 2.5 2.6e-69 232.5 2.5 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) DUF4346 PF14251.6 ETS73594.1 - 0.13 12.3 0.1 0.37 10.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) Prp18 PF02840.15 ETS73594.1 - 0.95 9.5 5.3 5.7 7.0 0.0 3.1 3 1 0 3 3 3 0 Prp18 domain YlqD PF11068.8 ETS73594.1 - 6.8 7.1 14.6 0.31 11.4 5.3 3.0 2 0 0 2 2 2 0 YlqD protein PIF1 PF05970.14 ETS73595.1 - 3.3e-62 210.8 0.1 8.5e-49 166.6 0.1 2.3 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 ETS73595.1 - 4.1e-22 78.8 0.0 7.3e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ETS73595.1 - 1.5e-10 41.6 0.0 5.7e-10 39.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 ETS73595.1 - 3.6e-06 27.3 0.0 9.7e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ETS73595.1 - 5.9e-05 23.5 0.0 0.00014 22.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Herpes_Helicase PF02689.14 ETS73595.1 - 0.00045 18.3 0.1 0.0012 16.9 0.0 1.6 2 0 0 2 2 2 1 Helicase AAA_7 PF12775.7 ETS73595.1 - 0.0005 19.6 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 ETS73595.1 - 0.00057 20.3 0.0 0.0014 19.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.6 ETS73595.1 - 0.00079 19.2 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain IstB_IS21 PF01695.17 ETS73595.1 - 0.00094 19.0 0.3 0.011 15.5 0.1 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.27 ETS73595.1 - 0.0063 17.0 4.4 0.028 14.9 0.0 3.0 1 1 1 2 2 2 1 ABC transporter PhoH PF02562.16 ETS73595.1 - 0.0074 15.8 0.0 0.024 14.1 0.0 1.9 1 0 0 1 1 1 1 PhoH-like protein T2SSE PF00437.20 ETS73595.1 - 0.0086 15.2 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 ETS73595.1 - 0.018 14.7 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF5605 PF18310.1 ETS73595.1 - 0.02 14.7 0.1 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5605) RsgA_GTPase PF03193.16 ETS73595.1 - 0.021 14.7 0.1 0.049 13.5 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 ETS73595.1 - 0.032 14.2 0.2 0.3 11.1 0.2 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 ETS73595.1 - 0.07 12.3 0.1 0.15 11.2 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 ETS73595.1 - 0.079 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AFG1_ATPase PF03969.16 ETS73595.1 - 0.12 11.3 0.0 0.27 10.1 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase Sigma54_activat PF00158.26 ETS73595.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 ETS73595.1 - 0.15 12.5 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase MAPEG PF01124.18 ETS73596.1 - 6.7e-15 55.1 3.6 8.1e-15 54.9 3.6 1.1 1 0 0 1 1 1 1 MAPEG family DUF1308 PF07000.11 ETS73597.1 - 8.9e-09 35.5 0.0 6.7e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) Recep_L_domain PF01030.24 ETS73599.1 - 0.0012 18.9 1.7 6.2 7.0 0.6 3.8 1 1 3 4 4 4 2 Receptor L domain Phage_holin_3_6 PF07332.11 ETS73599.1 - 0.016 15.2 0.1 0.034 14.2 0.1 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III LRR_5 PF13306.6 ETS73599.1 - 0.045 13.7 0.3 0.24 11.4 0.3 1.8 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) Podoplanin PF05808.11 ETS73599.1 - 0.047 13.8 0.4 0.087 12.9 0.4 1.4 1 0 0 1 1 1 0 Podoplanin Amnionless PF14828.6 ETS73599.1 - 0.076 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Amnionless Phage_holin_2_4 PF16082.5 ETS73599.1 - 0.17 11.6 0.5 0.43 10.3 0.5 1.7 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DNA_ligase_A_M PF01068.21 ETS73600.1 - 1.3e-43 149.1 0.0 6.5e-43 146.8 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ETS73600.1 - 2.7e-41 141.8 0.0 5.3e-41 140.8 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 ETS73600.1 - 5.3e-16 58.8 0.0 6.2e-09 36.2 0.0 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 ETS73600.1 - 5.5e-16 59.3 0.0 1.5e-15 57.9 0.0 1.8 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 ETS73600.1 - 1.3e-13 51.3 0.0 4.8e-13 49.5 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 ETS73600.1 - 1e-08 35.4 0.1 8.6e-07 29.3 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 ETS73600.1 - 8.8e-05 22.5 0.2 0.0002 21.4 0.2 1.6 1 0 0 1 1 1 1 DNA ligase IV LIG3_BRCT PF16759.5 ETS73600.1 - 0.0012 19.1 0.1 0.037 14.3 0.1 2.5 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain mRNA_cap_enzyme PF01331.19 ETS73600.1 - 0.02 14.7 0.1 0.3 10.9 0.0 2.5 3 0 0 3 3 3 0 mRNA capping enzyme, catalytic domain PTCB-BRCT PF12738.7 ETS73600.1 - 0.021 14.8 0.0 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 twin BRCT domain UPRTase PF14681.6 ETS73601.1 - 1.8e-73 246.4 0.0 2e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 ETS73601.1 - 0.0003 20.3 0.0 0.00054 19.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NAD_binding_10 PF13460.6 ETS73601.1 - 0.0097 15.8 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding TMP-TENI PF02581.17 ETS73601.1 - 0.028 13.8 0.4 0.26 10.6 0.2 2.0 2 0 0 2 2 2 0 Thiamine monophosphate synthase CRCB PF02537.15 ETS73602.1 - 2.1e-34 117.7 16.1 8.5e-22 77.3 7.4 2.5 2 1 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) DUF2201_N PF13203.6 ETS73602.1 - 0.091 12.3 0.5 0.13 11.8 0.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2968 PF11180.8 ETS73602.1 - 0.15 11.7 3.8 0.26 10.9 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) YjeF_N PF03853.15 ETS73603.1 - 1.9e-39 135.3 0.1 2.7e-39 134.8 0.1 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 ETS73603.1 - 2.8e-13 50.7 0.7 2.8e-13 50.7 0.7 1.9 2 0 0 2 2 2 1 FDF domain DEC-1_N PF04625.13 ETS73603.1 - 0.016 14.2 8.5 0.042 12.9 8.5 1.7 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Aldo_ket_red PF00248.21 ETS73604.1 - 1.6e-60 204.8 0.0 2e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Amidohydro_2 PF04909.14 ETS73605.1 - 8.2e-40 137.4 0.3 1.1e-39 137.0 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase PRK PF00485.18 ETS73606.1 - 8.7e-59 198.6 0.0 1.2e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 ETS73606.1 - 5.3e-41 140.4 0.0 7.8e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 ETS73606.1 - 2.6e-05 24.8 0.0 5.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ETS73606.1 - 0.00041 20.5 0.0 0.0052 16.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain CPT PF07931.12 ETS73606.1 - 0.00075 19.4 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 ETS73606.1 - 0.0012 19.3 0.2 0.69 10.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 ETS73606.1 - 0.0028 18.2 0.3 0.059 13.9 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.12 ETS73606.1 - 0.0042 16.4 0.0 0.009 15.3 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.29 ETS73606.1 - 0.012 16.0 0.0 0.033 14.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 ETS73606.1 - 0.017 14.3 0.1 0.054 12.7 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain MobB PF03205.14 ETS73606.1 - 0.043 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SSE PF00437.20 ETS73606.1 - 0.074 12.1 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CLTH PF10607.9 ETS73607.1 - 6.1e-32 110.6 0.0 8.3e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 ETS73607.1 - 2e-06 27.5 0.0 4.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 LisH ETC_C1_NDUFA4 PF04800.12 ETS73608.1 - 3e-37 126.8 1.0 4.9e-37 126.1 1.0 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Mucin PF01456.17 ETS73608.1 - 1.1 9.2 9.8 1.6 8.7 9.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein F1F0-ATPsyn_F PF10791.9 ETS73609.1 - 5.3e-41 139.0 0.1 6e-41 138.8 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi FANCD2OS PF15124.6 ETS73610.1 - 0.076 13.2 0.2 0.2 11.8 0.2 1.6 1 0 0 1 1 1 0 FANCD2 opposite strand protein DUF3716 PF12511.8 ETS73611.1 - 1.5e-09 37.7 3.4 2.2e-09 37.2 3.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF5131 PF07505.11 ETS73611.1 - 0.04 13.4 0.0 0.051 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) MCM PF00493.23 ETS73612.1 - 1.2e-103 345.0 0.4 1.9e-103 344.4 0.4 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ETS73612.1 - 7.3e-39 132.5 0.5 1.5e-38 131.5 0.5 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 ETS73612.1 - 3.9e-32 110.7 1.1 8.9e-32 109.5 1.1 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 ETS73612.1 - 4.1e-25 88.0 0.3 1.5e-24 86.2 0.1 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 ETS73612.1 - 1.2e-24 86.9 0.3 1.2e-24 86.9 0.3 2.4 4 0 0 4 4 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ETS73612.1 - 3e-07 30.0 0.0 1.1e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 ETS73612.1 - 0.00071 19.4 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ETS73612.1 - 0.0014 18.4 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain GIDA_assoc PF13932.6 ETS73612.1 - 0.012 15.8 2.2 0.029 14.5 2.2 1.7 1 0 0 1 1 1 0 GidA associated domain AAA_5 PF07728.14 ETS73612.1 - 0.028 14.4 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CCDC53 PF10152.9 ETS73612.1 - 0.83 10.1 3.2 1.7 9.1 0.2 2.7 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex DUF1593 PF07632.11 ETS73614.1 - 3.3e-90 302.0 0.0 4.4e-90 301.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 ETS73614.1 - 0.012 14.5 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 REJ domain DUF4360 PF14273.6 ETS73615.1 - 3.2e-61 206.3 4.4 6.4e-59 198.8 0.9 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4360) IBR PF01485.21 ETS73616.1 - 8.9e-19 67.5 20.7 3.1e-11 43.3 5.7 5.5 5 1 1 6 6 6 3 IBR domain, a half RING-finger domain FAD_binding_4 PF01565.23 ETS73617.1 - 4.1e-23 81.7 2.2 7.1e-23 80.9 2.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS73617.1 - 0.00026 21.1 0.0 0.00072 19.6 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Dabb PF07876.12 ETS73618.1 - 1.7e-21 76.6 0.0 2.6e-19 69.6 0.0 2.1 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain RTA1 PF04479.13 ETS73620.1 - 2e-28 99.4 7.8 2e-28 99.4 7.8 1.7 1 1 1 2 2 2 1 RTA1 like protein DUF3810 PF12725.7 ETS73620.1 - 0.015 14.6 1.0 0.027 13.8 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF2070 PF09843.9 ETS73620.1 - 0.64 8.2 12.0 0.8 7.9 12.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF202 PF02656.15 ETS73620.1 - 6.7 7.2 14.5 5.1 7.6 0.8 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF202) MFS_1 PF07690.16 ETS73622.1 - 4.2e-28 98.3 71.9 2.8e-17 62.7 41.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS73622.1 - 0.14 10.6 30.0 0.0098 14.5 14.5 2.3 1 1 1 2 2 2 0 MFS/sugar transport protein HeLo PF14479.6 ETS73623.1 - 0.014 15.2 2.7 0.014 15.2 2.7 1.9 2 0 0 2 2 2 0 Prion-inhibition and propagation Zn_clus PF00172.18 ETS73626.1 - 7.3e-08 32.4 10.1 1.3e-07 31.6 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS73626.1 - 2.2e-05 23.5 0.0 4.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PLDc PF00614.22 ETS73628.1 - 1.7e-15 56.5 1.7 4.8e-07 29.7 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 ETS73628.1 - 7.1e-14 51.8 0.4 2.3e-06 27.5 0.0 3.7 4 0 0 4 4 4 3 PLD-like domain Glyco_hydro_cc PF11790.8 ETS73629.1 - 3.6e-52 177.3 0.0 4.4e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core TPR_12 PF13424.6 ETS73630.1 - 8.3e-07 29.2 3.2 0.00066 19.9 0.3 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ETS73630.1 - 0.0003 20.7 0.8 0.69 10.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 ETS73630.1 - 0.0025 17.5 2.7 0.8 9.6 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 ETS73630.1 - 0.01 15.8 0.1 7.5 6.8 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS73630.1 - 0.017 15.6 1.5 0.044 14.3 0.6 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat MRI PF15325.6 ETS73630.1 - 3.3 8.8 7.4 0.31 12.1 2.2 2.0 2 0 0 2 2 2 0 Modulator of retrovirus infection HAD_2 PF13419.6 ETS73631.1 - 1.2e-15 58.1 0.0 5.1e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETS73631.1 - 4.9e-08 33.5 0.0 5.3e-07 30.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ETS73631.1 - 0.0066 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Fungal_trans_2 PF11951.8 ETS73632.1 - 1.6e-09 37.1 1.5 3.1e-09 36.1 1.5 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain VF530 PF09905.9 ETS73632.1 - 0.014 15.6 0.2 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 DNA-binding protein VF530 WD40 PF00400.32 ETS73633.1 - 4.6e-13 49.4 4.8 0.012 16.4 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS73633.1 - 4.6e-05 23.6 1.1 0.29 11.5 0.0 4.0 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Acyltransferase PF01553.21 ETS73634.1 - 4.3e-16 58.8 0.0 7.5e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase UPF0086 PF01868.16 ETS73635.1 - 8.4e-33 112.1 0.0 8.1e-32 109.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function UPF0086 Beta-lactamase PF00144.24 ETS73636.1 - 6.2e-31 107.9 0.1 1.1e-30 107.0 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase XAP5 PF04921.14 ETS73637.1 - 5.3e-93 311.4 3.2 5.3e-93 311.4 3.2 1.5 2 0 0 2 2 2 1 XAP5, circadian clock regulator DUF4604 PF15377.6 ETS73637.1 - 0.0027 18.1 4.2 0.0027 18.1 4.2 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4604) HET PF06985.11 ETS73638.1 - 8.7e-23 81.3 0.7 1.5e-22 80.6 0.7 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 ETS73639.1 - 1.2e-41 142.9 29.6 1.9e-40 138.9 13.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS73639.1 - 7.1e-05 21.8 0.2 0.24 10.2 0.6 2.8 2 1 0 2 2 2 2 MFS_1 like family DUF5493 PF17597.2 ETS73639.1 - 0.031 14.5 0.9 0.12 12.7 0.8 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5493) DUF5325 PF17259.2 ETS73639.1 - 0.05 13.5 0.3 0.05 13.5 0.3 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5325) CrgA PF06781.12 ETS73639.1 - 5.3 7.2 5.7 11 6.1 0.2 3.1 3 0 0 3 3 3 0 Cell division protein CrgA Fip1 PF05182.13 ETS73640.1 - 6e-20 70.5 1.1 1.1e-19 69.6 1.1 1.5 1 0 0 1 1 1 1 Fip1 motif FAM117 PF15388.6 ETS73640.1 - 0.021 14.3 2.3 0.03 13.7 2.3 1.2 1 0 0 1 1 1 0 Protein Family FAM117 YL1 PF05764.13 ETS73640.1 - 0.59 10.2 6.3 0.73 9.9 6.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nucleoporin_FG PF13634.6 ETS73641.1 - 2.2e-09 38.0 78.6 7e-05 23.6 28.4 3.7 2 1 1 3 3 3 2 Nucleoporin FG repeat region Fib_alpha PF08702.10 ETS73641.1 - 0.0087 16.3 0.6 0.4 10.9 0.0 2.5 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family YflT PF11181.8 ETS73641.1 - 0.13 12.8 1.2 0.39 11.2 0.1 2.4 2 0 0 2 2 2 0 Heat induced stress protein YflT Not3 PF04065.15 ETS73641.1 - 0.15 11.4 2.0 0.47 9.8 0.3 2.1 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Spc7 PF08317.11 ETS73641.1 - 0.38 9.6 3.8 1.4 7.8 0.1 2.6 3 0 0 3 3 3 0 Spc7 kinetochore protein MscS_porin PF12795.7 ETS73641.1 - 1.1 8.8 7.8 0.55 9.7 0.1 3.1 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.12 ETS73641.1 - 3.4 7.7 6.2 3.5 7.7 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) MFS_1 PF07690.16 ETS73642.1 - 1.2e-18 67.2 13.4 7.6e-18 64.5 14.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 ETS73642.1 - 0.0077 14.2 0.0 0.01 13.8 0.0 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family MFS_1 PF07690.16 ETS73643.1 - 8.3e-12 44.7 29.5 3.4e-06 26.2 16.5 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily SNO PF01174.19 ETS73644.1 - 3.3e-54 183.6 0.0 1.8e-43 148.6 0.0 2.0 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 ETS73644.1 - 1.6e-09 37.6 0.0 2.1e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 ETS73644.1 - 0.00089 19.0 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.28 ETS73644.1 - 0.001 18.9 0.0 0.013 15.3 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 ETS73644.1 - 0.0047 16.7 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family SOR_SNZ PF01680.17 ETS73645.1 - 1.1e-104 348.7 4.0 1.5e-104 348.3 4.0 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 ETS73645.1 - 1.5e-09 37.5 2.3 2.1e-06 27.3 0.1 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 ETS73645.1 - 0.0016 17.6 0.7 0.63 9.1 0.1 2.7 2 1 1 3 3 3 2 Dihydrouridine synthase (Dus) NanE PF04131.14 ETS73645.1 - 0.0033 16.6 0.8 0.06 12.5 0.0 2.7 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 ETS73645.1 - 0.013 14.7 0.0 0.38 9.9 0.0 2.5 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase TetR_C_27 PF17935.1 ETS73645.1 - 0.021 14.9 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 ETS73645.1 - 0.021 14.3 0.4 0.34 10.3 0.0 2.6 2 1 0 2 2 2 0 Histidine biosynthesis protein TMP-TENI PF02581.17 ETS73645.1 - 0.1 11.9 2.2 1.2 8.5 0.0 3.1 4 0 0 4 4 4 0 Thiamine monophosphate synthase Chaperone_III PF07824.12 ETS73645.1 - 0.21 11.8 0.0 1.1 9.6 0.0 1.9 2 0 0 2 2 2 0 Type III secretion chaperone domain NMO PF03060.15 ETS73645.1 - 0.42 10.0 10.4 0.072 12.5 1.5 2.4 2 1 0 2 2 2 0 Nitronate monooxygenase SKG6 PF08693.10 ETS73646.1 - 0.0017 17.7 0.3 0.0017 17.7 0.3 2.2 2 1 0 2 2 2 1 Transmembrane alpha-helix domain DUF2353 PF09789.9 ETS73649.1 - 0.0002 20.8 1.3 0.00021 20.8 0.2 1.5 2 0 0 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) DUF413 PF04219.12 ETS73649.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF DUF1664 PF07889.12 ETS73649.1 - 0.25 11.4 0.7 0.5 10.4 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fungal_trans PF04082.18 ETS73650.1 - 0.00084 18.4 0.1 0.0014 17.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CFEM PF05730.11 ETS73651.1 - 1.2e-12 47.7 11.9 1.2e-12 47.7 11.9 1.6 2 0 0 2 2 2 1 CFEM domain GMC_oxred_N PF00732.19 ETS73652.1 - 2.3e-26 92.9 0.0 5.8e-17 62.0 0.0 3.4 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS73652.1 - 1.8e-25 90.1 0.0 3.2e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 ETS73652.1 - 3.4e-05 24.0 0.2 9.4e-05 22.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 ETS73652.1 - 0.013 15.2 0.5 0.034 13.8 0.6 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 ETS73652.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS73652.1 - 0.081 12.0 1.4 0.12 11.4 1.4 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 ETS73652.1 - 0.11 11.2 0.3 0.15 10.7 0.3 1.1 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 ETS73652.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Sugar_tr PF00083.24 ETS73653.1 - 6.2e-74 249.5 18.2 7.6e-74 249.2 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS73653.1 - 1.4e-23 83.4 30.5 1.1e-19 70.6 11.2 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 ETS73654.1 - 5.6e-20 72.2 0.0 1.2e-19 71.1 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 ETS73656.1 - 3.9e-38 131.3 47.6 3.2e-35 121.7 26.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4381 PF14316.6 ETS73656.1 - 0.086 13.1 1.4 15 5.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DUF4131 PF13567.6 ETS73656.1 - 6.2 6.4 11.6 3.5 7.3 2.8 3.6 2 2 2 4 4 4 0 Domain of unknown function (DUF4131) Cu-oxidase_2 PF07731.14 ETS73657.1 - 4.3e-40 136.6 6.8 2e-38 131.2 0.5 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ETS73657.1 - 1.8e-37 128.0 2.5 4.4e-37 126.7 2.5 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 ETS73657.1 - 5.8e-35 120.8 2.8 5.6e-33 114.3 1.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase CENP-L PF13092.6 ETS73660.1 - 3.1e-28 99.0 0.0 1.2e-27 97.1 0.0 1.8 1 1 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Ank_4 PF13637.6 ETS73661.1 - 3.2e-11 43.5 0.3 2.2e-06 28.1 0.1 3.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS73661.1 - 2.7e-09 37.5 0.0 0.00018 22.0 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 ETS73661.1 - 3e-09 36.9 0.3 0.27 11.7 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 ETS73661.1 - 5.3e-08 32.5 0.2 0.71 10.6 0.1 4.8 5 0 0 5 5 4 2 Ankyrin repeat Ank_5 PF13857.6 ETS73661.1 - 7.3e-08 32.5 0.2 0.019 15.3 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) KilA-N PF04383.13 ETS73661.1 - 0.0021 17.9 0.2 0.0021 17.9 0.2 2.5 2 1 0 2 2 2 1 KilA-N domain Exonuc_VII_L PF02601.15 ETS73661.1 - 0.11 12.1 4.2 0.22 11.1 4.2 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 ETS73661.1 - 0.12 12.7 6.7 0.26 11.6 6.7 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FapA PF03961.13 ETS73661.1 - 0.33 9.5 3.8 0.45 9.1 1.6 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A Seryl_tRNA_N PF02403.22 ETS73661.1 - 0.6 10.4 8.1 15 5.9 7.6 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HCMV_UL139 PF12507.8 ETS73661.1 - 0.76 10.2 3.1 17 5.8 0.7 2.5 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein VSG_B PF13206.6 ETS73661.1 - 0.97 8.6 5.5 1.7 7.8 5.5 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain Cgr1 PF03879.14 ETS73661.1 - 1.3 9.4 5.1 3.5 8.1 5.1 1.6 1 0 0 1 1 1 0 Cgr1 family LMBR1 PF04791.16 ETS73661.1 - 1.5 7.7 3.1 2.3 7.0 3.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 ETS73661.1 - 2.4 8.2 4.5 3.5 7.7 3.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 ETS73661.1 - 5.7 6.1 5.1 10 5.3 5.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein Complex1_LYR PF05347.15 ETS73662.1 - 3.5e-06 27.0 1.2 7.8e-06 25.9 1.2 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ETS73662.1 - 0.046 14.5 0.7 0.1 13.4 0.7 1.6 1 0 0 1 1 1 0 Complex1_LYR-like Acetyltransf_1 PF00583.25 ETS73663.1 - 2.8e-16 59.8 0.0 3.7e-16 59.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS73663.1 - 1.9e-07 31.4 0.0 3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS73663.1 - 2.8e-07 30.4 0.0 5.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 ETS73663.1 - 2.9e-07 30.5 0.0 4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ETS73663.1 - 0.0011 19.2 0.1 0.0041 17.3 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ETS73663.1 - 0.0055 17.4 0.0 0.0067 17.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4349 PF14257.6 ETS73663.1 - 0.02 14.4 0.1 0.028 13.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Acetyltransf_CG PF14542.6 ETS73663.1 - 0.058 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Lipase_chap PF03280.14 ETS73664.1 - 2.8 7.8 6.9 0.82 9.6 0.9 2.6 2 1 1 3 3 3 0 Proteobacterial lipase chaperone protein F-box_4 PF15966.5 ETS73666.1 - 0.00015 21.7 0.0 0.00046 20.1 0.0 1.8 2 0 0 2 2 2 1 F-box F-box PF00646.33 ETS73666.1 - 0.056 13.3 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 F-box domain CHDCT2 PF08074.11 ETS73668.1 - 0.65 10.1 2.4 0.75 10.0 0.1 2.1 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain FAD_binding_3 PF01494.19 ETS73669.1 - 6.9e-15 55.1 7.6 2.8e-14 53.1 4.9 2.4 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 ETS73669.1 - 7.4e-06 26.1 0.2 1.8e-05 24.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS73669.1 - 3.1e-05 23.4 0.8 0.00068 19.0 0.7 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS73669.1 - 0.00014 21.1 0.7 0.00036 19.7 0.7 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 ETS73669.1 - 0.0003 20.8 1.6 0.0021 18.0 1.6 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 ETS73669.1 - 0.00038 20.2 2.4 0.00038 20.2 2.4 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS73669.1 - 0.00039 19.8 2.2 0.0017 17.7 0.1 2.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ETS73669.1 - 0.00085 18.3 0.0 0.0083 15.0 0.0 2.0 1 1 1 2 2 2 1 Tryptophan halogenase Flavi_NS5 PF00972.20 ETS73669.1 - 0.0055 14.9 1.3 0.3 9.2 0.1 2.1 2 0 0 2 2 2 2 Flavivirus RNA-directed RNA polymerase Pyr_redox PF00070.27 ETS73669.1 - 0.0078 16.7 1.5 0.015 15.9 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS73669.1 - 0.02 14.1 0.2 0.033 13.4 0.2 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 ETS73669.1 - 0.022 14.1 0.8 0.082 12.2 1.0 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ETS73669.1 - 0.024 13.3 0.9 0.046 12.4 0.9 1.4 1 0 0 1 1 1 0 HI0933-like protein KTSC PF13619.6 ETS73669.1 - 0.04 13.7 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 KTSC domain GIDA PF01134.22 ETS73669.1 - 0.067 12.3 0.5 0.1 11.7 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Condensation PF00668.20 ETS73670.1 - 8.6e-74 248.8 0.0 1.7e-43 149.0 0.0 2.2 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.28 ETS73670.1 - 8.1e-70 235.5 0.0 1e-68 231.9 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.25 ETS73670.1 - 1.6e-30 105.2 0.2 1.7e-14 53.9 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site WES_acyltransf PF03007.16 ETS73670.1 - 0.00098 19.0 0.5 0.015 15.1 0.2 2.6 2 1 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Myb_DNA-bind_3 PF12776.7 ETS73671.1 - 9.3e-23 81.0 0.3 1.9e-22 80.1 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Med13_C PF06333.12 ETS73671.1 - 0.07 12.4 3.5 0.093 12.0 3.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain SOG2 PF10428.9 ETS73671.1 - 3.6 6.7 10.6 4.7 6.3 10.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Asp PF00026.23 ETS73672.1 - 4.4e-67 226.7 6.8 5.4e-67 226.5 6.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS73672.1 - 8.4e-07 29.4 3.4 0.0013 19.0 1.1 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ETS73672.1 - 0.0097 16.5 4.5 0.3 11.7 1.2 3.3 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 ETS73672.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DUF4470 PF14737.6 ETS73674.1 - 3.2e-24 84.9 0.1 8.1e-24 83.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TehB PF03848.14 ETS73674.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Hydrolase_4 PF12146.8 ETS73675.1 - 1.5e-05 24.4 0.0 0.014 14.6 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS73675.1 - 2.3e-05 24.2 0.0 2.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS73675.1 - 0.00058 19.4 0.1 0.13 11.7 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family VirJ PF06057.11 ETS73675.1 - 0.015 15.2 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) DUF915 PF06028.11 ETS73675.1 - 0.016 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) FSH1 PF03959.13 ETS73675.1 - 0.089 12.4 0.0 0.3 10.7 0.0 1.8 1 1 1 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 ETS73675.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 ETS73675.1 - 0.2 11.4 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_7 PF12715.7 ETS73675.1 - 0.21 10.8 0.0 3.9 6.6 0.0 2.0 2 0 0 2 2 2 0 Abhydrolase family MFS_1 PF07690.16 ETS73676.1 - 2.2e-31 109.1 41.8 7e-31 107.4 42.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Orf78 PF06024.12 ETS73676.1 - 0.011 16.0 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 Orf78 (ac78) NiFe_hyd_3_EhaA PF17367.2 ETS73676.1 - 0.21 11.7 3.9 2.3 8.4 0.1 3.5 3 0 0 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A SieB PF14163.6 ETS73676.1 - 0.6 9.6 0.0 0.6 9.6 0.0 2.4 3 0 0 3 3 3 0 Super-infection exclusion protein B DUF5367 PF17329.2 ETS73676.1 - 0.7 10.0 5.8 0.69 10.1 0.8 3.4 4 0 0 4 4 4 0 Family of unknown function (DUF5367) DUF3431 PF11913.8 ETS73679.1 - 3.5e-56 190.4 0.1 4e-56 190.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) AIM24 PF01987.17 ETS73680.1 - 3.5e-51 173.9 0.0 4.3e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Acyl-CoA_dh_1 PF00441.24 ETS73681.1 - 3.5e-37 127.9 1.0 6.6e-37 127.0 1.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ETS73681.1 - 6.7e-17 61.5 0.1 1.2e-16 60.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ETS73681.1 - 8.5e-12 45.5 0.1 1.9e-11 44.4 0.1 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ETS73681.1 - 5.2e-07 30.3 0.0 1.2e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 ETS73681.1 - 0.00084 19.1 0.0 0.002 17.8 0.0 1.5 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal APH PF01636.23 ETS73682.1 - 3.3e-42 145.1 0.0 8.3e-42 143.7 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ETS73682.1 - 2.8e-05 23.6 0.0 5.7e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 ETS73682.1 - 0.0054 16.3 0.0 0.37 10.3 0.0 2.2 2 0 0 2 2 2 1 RIO1 family DUF1679 PF07914.11 ETS73682.1 - 0.0055 15.6 0.0 0.025 13.4 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) Pkinase PF00069.25 ETS73682.1 - 0.017 14.5 0.0 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain Kdo PF06293.14 ETS73682.1 - 0.018 14.4 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.14 ETS73682.1 - 0.047 12.9 0.0 0.78 8.9 0.0 2.2 1 1 0 1 1 1 0 Fructosamine kinase Gpi1 PF05024.15 ETS73683.1 - 5.5e-78 261.3 8.2 9.8e-78 260.5 8.2 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) 7tm_1 PF00001.21 ETS73683.1 - 0.0024 17.2 2.2 0.005 16.2 1.0 2.0 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DNA_pol_A_exo1 PF01612.20 ETS73685.1 - 3.2e-39 134.4 0.2 5.4e-39 133.7 0.2 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 ETS73685.1 - 3e-28 98.3 0.6 1.2e-27 96.4 0.6 2.2 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 ETS73685.1 - 2.1e-12 46.8 0.1 4.5e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 HRDC domain Rrn6 PF10214.9 ETS73685.1 - 0.097 11.1 6.7 0.14 10.6 6.7 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor NARP1 PF12569.8 ETS73685.1 - 2.2 7.1 8.7 6.4 5.6 8.7 1.7 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 GCV_T PF01571.21 ETS73686.1 - 7.5e-43 146.8 0.0 1.1e-42 146.2 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 ETS73686.1 - 0.003 17.5 0.0 0.0075 16.2 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF3431 PF11913.8 ETS73686.1 - 0.19 11.5 0.7 0.53 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3431) adh_short_C2 PF13561.6 ETS73687.1 - 6.1e-36 124.2 0.3 7.7e-36 123.8 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS73687.1 - 1.2e-22 80.3 0.2 1.9e-22 79.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short PF00106.25 ETS73688.1 - 6.5e-17 61.6 0.3 6.9e-17 61.5 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS73688.1 - 8.9e-17 61.4 0.3 9.9e-17 61.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS73688.1 - 4.9e-07 29.8 0.2 5.5e-07 29.7 0.2 1.0 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS73688.1 - 0.00061 19.3 0.0 0.00069 19.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 ETS73688.1 - 0.00098 19.0 0.3 0.0014 18.5 0.3 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Ldh_1_N PF00056.23 ETS73688.1 - 0.022 14.8 0.1 0.024 14.7 0.1 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ZNRF_3_ecto PF18212.1 ETS73688.1 - 0.024 14.6 0.1 0.029 14.3 0.1 1.2 1 0 0 1 1 1 0 ZNRF-3 Ectodomain THF_DHG_CYH_C PF02882.19 ETS73688.1 - 0.044 13.1 0.1 0.1 11.9 0.0 1.6 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UPF0146 PF03686.13 ETS73688.1 - 0.048 13.5 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Polysacc_synt_2 PF02719.15 ETS73688.1 - 0.073 12.2 0.1 0.087 11.9 0.1 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 ETS73688.1 - 0.074 12.4 0.1 0.093 12.1 0.1 1.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thiolase_C PF02803.18 ETS73688.1 - 0.084 12.5 0.7 0.17 11.6 0.3 1.7 1 1 1 2 2 2 0 Thiolase, C-terminal domain Thioesterase PF00975.20 ETS73689.1 - 3.9e-10 40.2 0.0 7.1e-10 39.4 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 ETS73689.1 - 3.5e-06 27.8 4.6 5.4e-06 27.2 4.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 ETS73689.1 - 0.0064 16.3 0.0 0.0087 15.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 ETS73689.1 - 0.029 14.2 0.1 0.058 13.2 0.0 1.5 1 1 1 2 2 2 0 alpha/beta hydrolase fold adh_short_C2 PF13561.6 ETS73690.1 - 7e-62 209.0 0.7 8.1e-62 208.8 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS73690.1 - 1e-40 139.3 0.7 1.4e-40 138.9 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS73690.1 - 2.7e-15 56.7 0.2 4e-15 56.2 0.2 1.2 1 0 0 1 1 1 1 KR domain Glyco_hydro_99 PF16317.5 ETS73690.1 - 0.064 12.4 0.1 0.14 11.3 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolase family 99 YjeF_N PF03853.15 ETS73690.1 - 0.098 12.5 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus NAD_binding_6 PF08030.12 ETS73691.1 - 3.1e-31 108.6 0.0 5.9e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ETS73691.1 - 6e-20 71.4 0.0 1.8e-19 69.8 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 ETS73691.1 - 6.6e-18 65.0 11.2 6.6e-18 65.0 11.2 2.5 1 1 1 2 2 2 1 Ferric reductase like transmembrane component UQ_con PF00179.26 ETS73692.1 - 8.9e-53 177.7 0.0 1e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ETS73692.1 - 0.0037 17.0 0.0 0.0047 16.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ETS73692.1 - 0.034 14.4 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 ETS73692.1 - 0.044 13.7 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain CVNH PF08881.10 ETS73693.1 - 1.2e-25 90.2 0.1 1.4e-25 89.9 0.1 1.1 1 0 0 1 1 1 1 CVNH domain p450 PF00067.22 ETS73694.1 - 1.5e-56 192.1 0.0 2e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TPR_10 PF13374.6 ETS73696.1 - 4.4e-26 90.0 30.1 0.00019 21.2 0.1 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 ETS73696.1 - 4.6e-19 68.5 29.4 2.2e-07 31.1 0.9 5.2 6 0 0 6 6 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 ETS73696.1 - 4.2e-15 56.0 17.9 0.081 13.4 0.0 7.8 2 2 5 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 ETS73696.1 - 4.8e-14 51.3 0.2 1.1 9.6 0.0 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS73696.1 - 6.5e-10 39.1 6.2 0.011 16.0 0.1 5.1 1 1 4 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 ETS73696.1 - 3.1e-09 36.2 10.7 2.8 8.3 0.1 7.9 7 0 0 7 7 7 2 Tetratricopeptide repeat NB-ARC PF00931.22 ETS73696.1 - 4.1e-09 36.0 0.0 3.5e-08 33.0 0.0 2.2 1 1 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.6 ETS73696.1 - 1.9e-05 25.1 27.4 3.7 8.6 0.1 8.9 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 ETS73696.1 - 3.9e-05 23.3 0.8 8.8 6.3 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 ETS73696.1 - 5.6e-05 23.5 9.2 18 6.2 0.1 7.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 ETS73696.1 - 9.1e-05 22.2 25.2 0.27 11.4 0.0 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat AAA_22 PF13401.6 ETS73696.1 - 0.00019 21.7 0.0 0.00073 19.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain Hydrolase_4 PF12146.8 ETS73696.1 - 0.0012 18.1 0.0 0.0029 16.9 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 ETS73696.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 ETS73696.1 - 0.0015 18.1 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Paf67 PF10255.9 ETS73696.1 - 0.0049 15.9 2.1 0.24 10.4 0.4 3.3 1 1 3 4 4 4 1 RNA polymerase I-associated factor PAF67 Abhydrolase_6 PF12697.7 ETS73696.1 - 0.0056 17.3 1.4 0.16 12.5 0.0 3.7 3 2 0 3 3 3 1 Alpha/beta hydrolase family DUF900 PF05990.12 ETS73696.1 - 0.0078 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PPR_2 PF13041.6 ETS73696.1 - 0.023 14.9 0.1 1.5e+02 2.7 0.0 5.3 6 0 0 6 6 6 0 PPR repeat family BRD4_CDT PF17105.5 ETS73696.1 - 0.038 13.6 0.2 15 5.3 0.0 3.5 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 SCFA_trans PF02667.14 ETS73696.1 - 0.12 11.3 0.1 0.24 10.3 0.1 1.4 1 0 0 1 1 1 0 Short chain fatty acid transporter AAA_16 PF13191.6 ETS73696.1 - 0.26 11.7 6.0 0.19 12.1 0.2 3.3 2 2 0 2 2 2 0 AAA ATPase domain Babuvirus_MP PF07234.11 ETS73696.1 - 1.6 8.9 5.0 11 6.2 0.7 3.5 1 1 3 5 5 5 0 Movement and RNA silencing protein TPR_4 PF07721.14 ETS73696.1 - 2.9 8.8 26.4 0.54 11.0 0.5 6.1 7 0 0 7 7 4 0 Tetratricopeptide repeat DUF3883 PF13020.6 ETS73697.1 - 1.7e-05 24.8 0.1 4.6e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3883) DUF443 PF04276.12 ETS73698.1 - 0.025 14.4 2.6 0.38 10.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) DUF3262 PF11660.8 ETS73698.1 - 4.6 7.7 8.9 24 5.4 2.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) EutB PF06751.11 ETS73699.1 - 0.23 10.3 0.0 7.9 5.2 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine ammonia lyase large subunit (EutB) GST_N PF02798.20 ETS73700.1 - 9.8e-12 45.1 0.0 1.7e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ETS73700.1 - 8.7e-11 41.9 0.0 1.4e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ETS73700.1 - 5.2e-10 39.4 0.0 9.2e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ETS73700.1 - 2.7e-08 34.0 0.0 5.2e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ETS73700.1 - 9.1e-07 29.2 0.0 2.4e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS73700.1 - 2.9e-05 24.0 0.0 5.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pectate_lyase_3 PF12708.7 ETS73701.1 - 3.9e-76 255.7 8.9 5e-69 232.4 3.6 2.9 2 0 0 2 2 2 2 Pectate lyase superfamily protein Peptidase_S8 PF00082.22 ETS73701.1 - 2.6e-12 46.6 0.3 7.1e-12 45.2 0.3 1.8 1 0 0 1 1 1 1 Subtilase family MF_alpha_N PF05436.11 ETS73703.1 - 0.011 15.7 0.3 0.018 15.0 0.3 1.4 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus HMG_CoA_synt_N PF01154.17 ETS73705.1 - 2.1e-81 272.0 0.0 2.4e-81 271.8 0.0 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 ETS73705.1 - 9.7e-06 25.4 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal DUF697 PF05128.12 ETS73705.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF697) DUF2235 PF09994.9 ETS73706.1 - 3.4e-75 253.1 0.0 3.4e-75 253.1 0.0 2.4 2 1 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF1682 PF07946.14 ETS73706.1 - 0.03 13.5 0.5 0.03 13.5 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) adh_short PF00106.25 ETS73707.1 - 9.2e-21 74.2 0.0 3.1e-20 72.5 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS73707.1 - 6.5e-13 48.8 0.0 9.4e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS73707.1 - 1.2e-05 25.3 0.1 2e-05 24.6 0.0 1.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 ETS73707.1 - 0.03 13.8 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 ETS73708.1 - 0.0036 17.4 9.9 0.008 16.3 9.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CPL PF08144.11 ETS73708.1 - 0.062 13.7 0.0 3.1 8.2 0.0 2.6 2 1 0 2 2 2 0 CPL (NUC119) domain FliT PF05400.13 ETS73708.1 - 0.079 13.8 1.7 0.71 10.7 0.0 3.0 2 0 0 2 2 2 0 Flagellar protein FliT DUF2599 PF10783.9 ETS73708.1 - 0.34 11.6 2.2 17 6.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2599) TPR_10 PF13374.6 ETS73709.1 - 3.6e-68 223.8 11.3 3.2e-10 39.5 0.4 7.7 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 ETS73709.1 - 1e-57 192.3 12.2 3.1e-18 65.8 1.3 6.9 3 1 4 7 7 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 ETS73709.1 - 1.2e-15 56.5 12.5 0.022 14.5 0.5 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 ETS73709.1 - 1.8e-15 55.7 13.4 0.0047 16.9 0.2 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 ETS73709.1 - 8e-14 52.0 5.6 0.0018 18.9 0.4 7.1 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 ETS73709.1 - 2.8e-13 49.1 12.6 0.31 11.8 0.0 8.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 ETS73709.1 - 6.4e-13 47.8 11.6 0.0019 18.3 0.2 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 ETS73709.1 - 2.6e-11 42.7 19.8 0.12 12.6 0.2 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 ETS73709.1 - 1.3e-10 41.2 10.4 2.3 9.3 0.2 8.5 8 1 1 9 9 8 3 Tetratricopeptide repeat NACHT PF05729.12 ETS73709.1 - 1.4e-08 34.8 0.0 3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 ETS73709.1 - 2.3e-08 33.8 0.2 1.7e-07 31.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain TPR_17 PF13431.6 ETS73709.1 - 5.8e-08 32.6 4.6 1.9 9.1 0.0 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 ETS73709.1 - 5.6e-07 30.0 14.6 0.065 13.8 2.9 5.8 3 2 3 6 6 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS73709.1 - 2.8e-06 27.5 0.1 0.39 11.0 0.0 5.2 1 1 3 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 NB-ARC PF00931.22 ETS73709.1 - 1e-05 24.9 0.0 8.9e-05 21.8 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain TPR_MalT PF17874.1 ETS73709.1 - 2.2e-05 24.0 6.3 0.012 15.0 3.0 2.7 1 1 0 2 2 2 2 MalT-like TPR region AAA_22 PF13401.6 ETS73709.1 - 0.0024 18.1 0.0 0.0061 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS73709.1 - 0.042 14.2 0.4 0.4 11.1 0.4 2.6 1 1 0 1 1 1 0 AAA ATPase domain Dynein_AAA_lid PF17852.1 ETS73709.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain MIT PF04212.18 ETS73709.1 - 0.19 11.8 2.3 0.48 10.5 0.3 2.7 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain AAA_7 PF12775.7 ETS73709.1 - 0.21 11.1 0.0 0.52 9.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region TPR_6 PF13174.6 ETS73709.1 - 0.92 10.3 6.7 4.6e+02 1.8 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 ETS73709.1 - 1.6 8.8 5.0 14 5.8 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 ETS73709.1 - 3 7.6 13.7 37 4.1 0.4 5.8 7 0 0 7 7 7 0 TPR repeat GST_N PF02798.20 ETS73710.1 - 2.1e-16 60.0 0.0 4.2e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ETS73710.1 - 1.2e-11 44.8 0.0 2e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ETS73710.1 - 2.7e-10 40.4 0.0 6e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ETS73710.1 - 1e-09 38.5 0.0 1.7e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ETS73710.1 - 8.2e-08 32.2 0.0 1.5e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ETS73710.1 - 8.7e-08 32.3 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Epimerase PF01370.21 ETS73711.1 - 1.2e-07 31.5 0.0 2.2e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ETS73711.1 - 0.00095 18.4 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein DUF1846 PF08903.11 ETS73712.1 - 0.09 11.3 0.3 0.13 10.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Sulfatase PF00884.23 ETS73713.1 - 3.8e-62 210.5 0.0 4.8e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 ETS73713.1 - 2.7e-19 69.4 9.1 5.8e-19 68.3 6.5 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 ETS73713.1 - 3e-05 23.8 1.5 0.0012 18.6 1.5 2.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 ETS73713.1 - 0.00051 18.8 0.5 0.001 17.7 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sugar_tr PF00083.24 ETS73714.1 - 1.1e-77 261.8 25.7 1.3e-77 261.6 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS73714.1 - 1.5e-12 47.2 46.3 1.3e-08 34.2 21.3 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS73714.1 - 0.0065 15.1 21.0 0.011 14.3 4.0 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein E1-E2_ATPase PF00122.20 ETS73714.1 - 5.1 6.6 8.9 8.7 5.8 4.7 2.6 2 0 0 2 2 2 0 E1-E2 ATPase Metallophos PF00149.28 ETS73715.1 - 3.2e-05 24.5 0.6 4.2e-05 24.1 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sec16_N PF12935.7 ETS73715.1 - 0.039 14.1 0.2 0.053 13.7 0.2 1.2 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus Metallophos_2 PF12850.7 ETS73715.1 - 0.078 13.2 1.4 1.1 9.4 1.2 2.2 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_49N PF17433.2 ETS73716.1 - 4.2e-47 160.2 0.0 4.2e-47 160.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 49 N-terminal Ig-like domain Glyco_hydro_49 PF03718.13 ETS73716.1 - 3.6e-17 62.4 0.0 9e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 B_solenoid_dext PF18841.1 ETS73716.1 - 5.6e-17 61.7 1.7 1.1e-16 60.8 0.5 2.2 2 0 0 2 2 2 1 Beta solenoid repeat from Dextranase IPU_b_solenoid PF18783.1 ETS73716.1 - 1.7e-10 40.8 2.7 4e-10 39.5 2.7 1.7 1 0 0 1 1 1 1 Isopullulanase beta-solenoid repeat HET PF06985.11 ETS73717.1 - 8.2e-27 94.4 0.0 2.7e-26 92.6 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ABM PF03992.16 ETS73718.1 - 0.00017 21.6 0.0 0.0002 21.4 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Fungal_trans PF04082.18 ETS73719.1 - 3.6e-07 29.5 0.2 9.5e-07 28.1 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS73719.1 - 6.6e-06 26.2 7.8 1.3e-05 25.2 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribonuc_red_lgN PF00317.21 ETS73719.1 - 0.11 12.6 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain FAD_binding_3 PF01494.19 ETS73720.1 - 4.4e-17 62.4 0.1 2.6e-11 43.4 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS73720.1 - 0.00015 21.9 0.0 0.00034 20.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS73720.1 - 0.0082 15.4 0.0 0.057 12.6 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS73720.1 - 0.057 12.7 0.0 0.33 10.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS73720.1 - 0.08 12.5 0.1 0.17 11.5 0.1 1.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase NmrA PF05368.13 ETS73721.1 - 2.1e-17 63.5 0.0 4.1e-17 62.5 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS73721.1 - 7.6e-12 45.5 0.0 1.4e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS73721.1 - 3.9e-09 36.3 0.0 5e-08 32.7 0.1 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ETS73721.1 - 7.3e-05 22.0 0.1 0.00011 21.5 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain LpxI_N PF17930.1 ETS73721.1 - 0.0001 22.2 0.0 0.0006 19.7 0.0 2.1 2 0 0 2 2 2 1 LpxI N-terminal domain KR PF08659.10 ETS73721.1 - 0.003 17.5 0.1 0.0062 16.5 0.1 1.6 1 1 0 1 1 1 1 KR domain DapB_N PF01113.20 ETS73721.1 - 0.0031 17.6 0.1 0.007 16.5 0.1 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 ETS73721.1 - 0.0076 16.5 0.1 0.014 15.6 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Glu_dehyd_C PF16912.5 ETS73721.1 - 0.014 14.9 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus CbiJ PF02571.14 ETS73721.1 - 0.025 14.1 0.1 0.046 13.2 0.0 1.5 2 0 0 2 2 2 0 Precorrin-6x reductase CbiJ/CobK Glyco_transf_4 PF13439.6 ETS73721.1 - 0.058 13.4 0.0 0.49 10.4 0.0 2.4 2 2 0 2 2 2 0 Glycosyltransferase Family 4 2-Hacid_dh_C PF02826.19 ETS73721.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Period_C PF12114.8 ETS73721.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region GDP_Man_Dehyd PF16363.5 ETS73721.1 - 0.16 11.4 0.1 1.1 8.6 0.2 2.4 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase Helo_like_N PF17111.5 ETS73722.1 - 0.00042 19.8 7.1 0.0011 18.4 3.5 2.5 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins DNA_repr_REX1B PF14966.6 ETS73722.1 - 0.012 16.3 1.3 0.046 14.4 1.3 2.1 1 0 0 1 1 1 0 DNA repair REX1-B PDCD9 PF07147.12 ETS73722.1 - 0.014 14.6 3.6 0.023 13.9 3.6 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S30 (PDCD9) Bacillus_HBL PF05791.11 ETS73722.1 - 0.4 10.5 5.3 0.52 10.1 1.9 2.6 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Troponin PF00992.20 ETS73722.1 - 0.44 10.8 5.5 2.2 8.6 2.2 2.5 2 0 0 2 2 2 0 Troponin HsbA PF12296.8 ETS73722.1 - 0.53 10.7 2.2 1.4 9.4 2.2 1.7 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Syntaxin-6_N PF09177.11 ETS73722.1 - 3.8 8.1 16.1 74 4.0 12.2 4.1 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 ETS73722.1 - 6 7.0 12.8 12 6.0 5.7 2.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ALMT PF11744.8 ETS73722.1 - 7.2 5.3 12.5 13 4.5 12.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4038 PF13204.6 ETS73723.1 - 2.1e-83 280.5 0.2 3.2e-83 279.9 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Collagen_bind_2 PF12904.7 ETS73723.1 - 1.2e-09 38.0 0.1 2.7e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 Putative collagen-binding domain of a collagenase YL1_C PF08265.11 ETS73723.1 - 0.2 11.5 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain Aldo_ket_red PF00248.21 ETS73724.1 - 1.1e-52 179.1 0.0 1.3e-52 178.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_16 PF00722.21 ETS73725.1 - 3.4e-07 29.9 5.0 5.8e-07 29.1 5.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 p450 PF00067.22 ETS73726.1 - 1.6e-51 175.5 0.0 4.3e-50 170.8 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Spc7 PF08317.11 ETS73727.1 - 2.8e-10 39.6 160.9 0.00047 19.1 33.7 6.9 1 1 6 7 7 7 5 Spc7 kinetochore protein GAS PF13851.6 ETS73727.1 - 8.8e-10 38.3 141.1 0.0037 16.6 17.9 7.8 1 1 7 8 8 8 6 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 ETS73727.1 - 3.5e-06 24.9 58.7 3.5e-06 24.9 58.7 3.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3584) ATG16 PF08614.11 ETS73727.1 - 2.6e-05 24.5 162.3 1.5 9.0 35.6 7.6 1 1 5 6 6 6 2 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 ETS73727.1 - 0.0002 21.4 158.4 0.29 11.2 4.6 9.0 1 1 9 10 10 10 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.12 ETS73727.1 - 0.00022 19.6 130.6 0.19 9.9 47.5 3.1 1 1 1 2 2 2 2 HOOK protein Tropomyosin_1 PF12718.7 ETS73727.1 - 0.00029 21.0 32.9 0.00029 21.0 32.9 8.0 1 1 6 7 7 6 3 Tropomyosin like HMMR_N PF15905.5 ETS73727.1 - 0.00038 20.1 150.7 0.0025 17.3 21.7 5.8 1 1 4 6 6 6 4 Hyaluronan mediated motility receptor N-terminal Filament PF00038.21 ETS73727.1 - 0.00046 19.9 127.9 0.62 9.6 17.2 6.9 1 1 5 7 7 7 6 Intermediate filament protein BRE1 PF08647.11 ETS73727.1 - 0.00051 20.1 154.0 0.046 13.8 15.8 9.5 3 3 4 8 8 7 4 BRE1 E3 ubiquitin ligase DUF4201 PF13870.6 ETS73727.1 - 0.00054 19.7 117.1 0.22 11.2 7.6 9.1 2 2 6 8 8 8 4 Domain of unknown function (DUF4201) DMPK_coil PF08826.10 ETS73727.1 - 0.0084 16.2 2.4 0.0084 16.2 2.4 12.6 6 3 9 15 15 11 1 DMPK coiled coil domain like GIT_CC PF16559.5 ETS73727.1 - 0.0098 15.7 6.3 0.0098 15.7 6.3 11.3 3 2 10 13 13 13 1 GIT coiled-coil Rho guanine nucleotide exchange factor Fez1 PF06818.15 ETS73727.1 - 0.01 16.3 137.3 0.61 10.5 26.0 6.2 1 1 5 6 6 6 0 Fez1 DUF724 PF05266.14 ETS73727.1 - 0.015 15.1 15.0 0.015 15.1 15.0 9.1 1 1 8 10 10 10 0 Protein of unknown function (DUF724) Spectrin PF00435.21 ETS73727.1 - 0.017 15.6 9.0 0.017 15.6 9.0 9.6 2 2 6 9 9 9 0 Spectrin repeat DUF4407 PF14362.6 ETS73727.1 - 0.018 14.4 134.8 0.17 11.2 23.7 6.0 1 1 5 6 6 6 0 Domain of unknown function (DUF4407) Tup_N PF08581.10 ETS73727.1 - 0.023 15.0 1.4 0.023 15.0 1.4 10.6 3 3 7 11 11 10 0 Tup N-terminal SlyX PF04102.12 ETS73727.1 - 0.025 15.2 3.0 0.025 15.2 3.0 13.9 2 2 13 15 15 15 0 SlyX KASH_CCD PF14662.6 ETS73727.1 - 0.056 13.3 144.8 0.46 10.3 30.3 5.9 1 1 5 6 6 6 0 Coiled-coil region of CCDC155 or KASH DUF1664 PF07889.12 ETS73727.1 - 0.18 11.9 84.7 1.2 9.2 3.1 9.1 1 1 9 11 11 11 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 ETS73727.1 - 0.21 11.8 87.1 0.045 13.9 12.4 8.1 1 1 5 8 8 8 0 Fibrinogen alpha/beta chain family Leu_zip PF15294.6 ETS73727.1 - 0.32 10.5 131.3 0.015 14.8 13.8 7.1 1 1 6 7 7 7 0 Leucine zipper ERM PF00769.19 ETS73727.1 - 0.38 10.5 183.7 0.19 11.5 34.4 6.0 1 1 4 5 5 5 0 Ezrin/radixin/moesin family Lebercilin PF15619.6 ETS73727.1 - 0.53 9.9 142.5 0.015 14.9 7.7 7.4 1 1 5 7 7 7 0 Ciliary protein causing Leber congenital amaurosis disease TPR_MLP1_2 PF07926.12 ETS73727.1 - 0.59 10.2 193.9 0.75 9.9 23.5 9.1 1 1 7 8 8 8 0 TPR/MLP1/MLP2-like protein MscS_porin PF12795.7 ETS73727.1 - 0.86 9.1 159.0 0.081 12.5 22.6 6.8 1 1 4 6 6 6 0 Mechanosensitive ion channel porin domain CALCOCO1 PF07888.11 ETS73727.1 - 3.1 6.6 141.8 0.21 10.4 48.9 4.8 1 1 2 4 4 4 0 Calcium binding and coiled-coil domain (CALCOCO1) like Golgin_A5 PF09787.9 ETS73727.1 - 6.3 6.2 137.8 0.44 10.0 25.6 6.3 1 1 5 6 6 6 0 Golgin subfamily A member 5 p450 PF00067.22 ETS73728.1 - 3.9e-42 144.6 0.0 5e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_3 PF00202.21 ETS73730.1 - 1.5e-115 386.1 0.0 1.7e-115 386.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ETS73730.1 - 0.03 13.5 0.0 0.041 13.1 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Hydrolase PF00702.26 ETS73731.1 - 1.1e-06 29.1 0.0 1.7e-06 28.5 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ETS73731.1 - 0.00085 19.4 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DAO PF01266.24 ETS73732.1 - 3.4e-45 155.2 1.6 4e-45 154.9 1.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS73732.1 - 8.1e-06 25.3 0.8 0.0058 15.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS73732.1 - 3.1e-05 24.1 0.0 7.7e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ETS73732.1 - 0.00011 21.6 0.0 0.00019 20.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 ETS73732.1 - 0.00012 22.1 0.1 0.00059 19.8 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ETS73732.1 - 0.00014 21.2 0.5 0.0074 15.5 0.2 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS73732.1 - 0.0016 17.6 2.5 0.0087 15.2 2.5 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ETS73732.1 - 0.0032 16.9 0.8 0.024 14.0 0.2 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase MCRA PF06100.11 ETS73732.1 - 0.0041 16.0 0.1 0.0092 14.8 0.0 1.5 2 0 0 2 2 2 1 MCRA family HI0933_like PF03486.14 ETS73732.1 - 0.027 13.2 0.1 1.8 7.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 ETS73732.1 - 0.046 12.8 0.2 0.11 11.5 0.1 1.7 1 1 1 2 2 2 0 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 ETS73732.1 - 0.18 12.0 0.1 0.53 10.6 0.1 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 ETS73732.1 - 0.73 10.4 3.6 25 5.5 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CBS PF00571.28 ETS73733.1 - 2.2e-36 124.1 8.5 2.1e-10 40.9 0.0 6.0 5 1 0 5 5 5 4 CBS domain PB1 PF00564.24 ETS73733.1 - 3.7e-09 36.4 0.4 9.7e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 PB1 domain Tyrosinase PF00264.20 ETS73734.1 - 1.4e-27 97.5 5.3 7e-13 49.4 2.3 2.2 1 1 1 2 2 2 2 Common central domain of tyrosinase Tyrosinase PF00264.20 ETS73735.1 - 5.1e-17 62.9 7.5 2.2e-16 60.8 7.3 2.1 1 1 0 1 1 1 1 Common central domain of tyrosinase Metallophos PF00149.28 ETS73736.1 - 1.3e-08 35.6 3.5 2.8e-08 34.5 3.5 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DuoxA PF10204.9 ETS73736.1 - 0.1 11.6 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Dual oxidase maturation factor Aldo_ket_red PF00248.21 ETS73737.1 - 1.5e-45 155.7 0.0 5.4e-34 117.7 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family P3A PF08727.11 ETS73737.1 - 0.085 12.2 0.9 5.7 6.4 0.0 2.6 3 0 0 3 3 3 0 Poliovirus 3A protein like BLACT_WH PF17778.1 ETS73737.1 - 0.23 11.5 2.4 8.8 6.4 0.0 3.0 3 0 0 3 3 3 0 Beta-lactamase associated winged helix domain GBP_PSP PF02425.15 ETS73738.1 - 0.011 15.4 6.9 11 5.7 0.0 3.7 4 0 0 4 4 4 0 Paralytic/GBP/PSP peptide ATP-synt_C PF00137.21 ETS73739.1 - 1.9e-10 40.9 11.7 1.9e-10 40.9 11.7 2.4 3 0 0 3 3 3 1 ATP synthase subunit C NEL PF14496.6 ETS73739.1 - 0.077 12.4 1.6 3 7.2 1.1 2.0 2 0 0 2 2 2 0 C-terminal novel E3 ligase, LRR-interacting WPP PF13943.6 ETS73739.1 - 0.16 12.4 3.2 0.24 11.8 3.2 1.3 1 0 0 1 1 1 0 WPP domain MOZ_SAS PF01853.18 ETS73741.1 - 1.4e-57 194.2 0.0 2.5e-57 193.4 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 ETS73741.1 - 9.6e-10 37.9 5.6 1.7e-08 33.9 5.6 2.3 1 1 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 ETS73741.1 - 0.098 13.1 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4666 PF15697.5 ETS73741.1 - 5 7.8 9.8 3.6 8.3 4.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) DFF40 PF09230.10 ETS73742.1 - 0.11 12.1 0.4 0.62 9.6 0.4 1.9 1 1 0 1 1 1 0 DNA fragmentation factor 40 kDa HET PF06985.11 ETS73743.1 - 3.7e-12 46.8 0.9 2.6e-09 37.6 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.19 ETS73744.1 - 2.1e-89 300.2 0.0 3.5e-89 299.5 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 ETS73744.1 - 1.2e-49 168.6 0.0 2.1e-49 167.7 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.17 ETS73744.1 - 7.4e-05 22.1 0.1 0.0084 15.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 ETS73744.1 - 0.00012 21.4 0.2 0.0005 19.4 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS73744.1 - 0.00032 20.9 0.0 0.00088 19.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS73744.1 - 0.0004 19.6 0.0 0.00068 18.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ETS73744.1 - 0.00058 18.7 0.0 0.00096 17.9 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 ETS73744.1 - 0.0013 18.4 0.1 0.0058 16.3 0.0 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ETS73744.1 - 0.0024 17.0 0.0 0.0037 16.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 ETS73744.1 - 0.0039 16.3 0.1 0.0097 15.0 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ETS73744.1 - 0.0069 16.9 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS73744.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ETS73744.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.10 ETS73744.1 - 0.039 13.0 0.0 0.86 8.6 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase AlaDh_PNT_C PF01262.21 ETS73744.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CLP1_P PF16575.5 ETS73745.1 - 5.5e-34 117.6 0.0 8.7e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 ETS73745.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RNA_polI_A34 PF08208.11 ETS73746.1 - 3.5e-30 105.7 31.3 3.5e-30 105.7 31.3 4.7 2 2 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Zn_clus PF00172.18 ETS73747.1 - 0.12 12.5 14.5 0.24 11.6 14.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAP2_3 PF14378.6 ETS73748.1 - 2.7e-21 76.1 16.1 2.7e-21 76.1 16.1 2.7 2 1 1 3 3 3 1 PAP2 superfamily PAP2 PF01569.21 ETS73748.1 - 1.6e-07 31.2 5.3 1.6e-07 31.2 5.3 2.6 2 1 0 2 2 2 1 PAP2 superfamily NACHT_N PF17100.5 ETS73749.1 - 6.8e-43 147.1 0.0 1.3e-42 146.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 ETS73749.1 - 1.3e-14 54.5 0.0 2.8e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Coatomer_WDAD PF04053.14 ETS73749.1 - 6.2e-06 25.5 0.0 2.8e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Coatomer WD associated region ANAPC4_WD40 PF12894.7 ETS73749.1 - 4.7e-05 23.6 0.3 0.49 10.7 0.0 5.1 5 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ETS73749.1 - 6.9e-05 23.6 13.2 0.047 14.6 0.1 6.3 6 0 0 6 6 6 2 WD domain, G-beta repeat AAA_16 PF13191.6 ETS73749.1 - 0.00083 19.8 0.0 0.0024 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 ETS73749.1 - 0.0035 17.7 0.0 0.0096 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ETS73749.1 - 0.03 14.7 0.0 0.093 13.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF4642 PF15484.6 ETS73749.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) PD40 PF07676.12 ETS73749.1 - 0.14 12.1 0.3 75 3.4 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Goodbye PF17109.5 ETS73749.1 - 0.18 12.3 0.2 3.4 8.1 0.0 2.9 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Pkinase PF00069.25 ETS73750.1 - 1.1e-71 241.3 0.0 1.4e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS73750.1 - 7e-30 104.2 0.0 9.2e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS73750.1 - 8.5e-07 28.6 0.0 1.6e-06 27.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ETS73750.1 - 0.00014 20.8 0.0 0.00025 20.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ETS73750.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ETS73750.1 - 0.0012 18.3 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 ETS73751.1 - 9.4e-166 538.9 38.0 1.3e-15 57.8 0.4 16.1 9 5 7 17 17 17 17 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS73751.1 - 4e-131 425.9 42.1 1.6e-09 38.1 0.1 23.6 12 6 15 27 27 27 26 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS73751.1 - 4.4e-109 343.1 41.5 0.00034 20.8 0.0 34.5 35 1 1 36 36 34 20 Ankyrin repeat Ank PF00023.30 ETS73751.1 - 1.1e-107 348.2 66.9 5.7e-06 26.5 0.1 33.1 30 2 1 31 31 31 23 Ankyrin repeat Ank_5 PF13857.6 ETS73751.1 - 1.9e-88 289.3 50.3 2.7e-07 30.7 0.1 25.6 9 6 16 27 27 27 20 Ankyrin repeats (many copies) NACHT PF05729.12 ETS73751.1 - 7.1e-09 35.8 0.0 2.3e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 NACHT domain NACHT_N PF17100.5 ETS73751.1 - 5e-06 26.5 1.0 1e-05 25.5 1.0 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase AAA_16 PF13191.6 ETS73751.1 - 0.00014 22.3 1.7 0.00092 19.6 0.0 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ETS73751.1 - 0.023 15.0 0.0 0.11 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 ETS73751.1 - 0.041 13.8 0.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PH_8 PF15409.6 ETS73751.1 - 0.12 12.7 0.1 23 5.3 0.0 3.0 2 0 0 2 2 2 0 Pleckstrin homology domain RF-1 PF00472.20 ETS73752.1 - 5.1e-14 52.2 0.3 7.1e-14 51.7 0.3 1.2 1 0 0 1 1 1 1 RF-1 domain DUF2913 PF11140.8 ETS73752.1 - 0.04 13.6 0.3 0.088 12.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2913) DUF2059 PF09832.9 ETS73752.1 - 0.12 12.5 0.3 0.94 9.6 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) RRM_1 PF00076.22 ETS73753.1 - 9.8e-11 41.3 0.0 1.6e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ETS73753.1 - 2.1e-05 24.1 0.0 4.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.22 ETS73754.1 - 2.5e-65 221.0 0.0 4.1e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 ETS73757.1 - 4.8e-21 75.4 0.0 4.3e-11 42.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 ETS73757.1 - 0.0002 21.1 0.2 0.0066 16.1 0.1 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS73757.1 - 0.00034 19.9 0.2 0.003 16.8 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS73757.1 - 0.0024 18.0 0.0 0.0051 17.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ETS73757.1 - 0.0095 16.5 0.2 0.95 10.1 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS73757.1 - 0.024 13.7 0.3 0.044 12.9 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain CobA_CobO_BtuR PF02572.15 ETS73757.1 - 0.039 14.2 0.1 0.063 13.5 0.1 1.3 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Lycopene_cycl PF05834.12 ETS73757.1 - 2.2 7.3 3.9 5.4 6.0 1.6 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein LETM1 PF07766.13 ETS73759.1 - 4.1e-11 42.8 0.1 1.4e-07 31.1 0.0 2.1 1 1 1 2 2 2 2 LETM1-like protein Lsr2 PF11774.8 ETS73759.1 - 0.089 12.9 0.7 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 Lsr2 Ribonuc_L-PSP PF01042.21 ETS73760.1 - 3.6e-30 104.5 0.0 4.1e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Dynamin_N PF00350.23 ETS73761.1 - 4.3e-31 108.2 0.0 9.5e-31 107.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 ETS73761.1 - 5.5e-30 104.6 0.1 1.4e-29 103.2 0.1 1.7 1 0 0 1 1 1 1 Dynamin central region GED PF02212.18 ETS73761.1 - 2.8e-05 24.2 2.0 0.0038 17.4 0.0 3.8 4 0 0 4 4 4 1 Dynamin GTPase effector domain NleF_casp_inhib PF16809.5 ETS73761.1 - 0.0011 18.9 0.5 0.19 11.6 0.0 3.6 3 1 2 5 5 5 1 NleF caspase inhibitor MMR_HSR1 PF01926.23 ETS73761.1 - 0.0013 18.8 0.0 0.0065 16.5 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 ETS73761.1 - 0.058 13.6 0.2 0.18 12.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain XFP_N PF09364.10 ETS73762.1 - 2e-170 566.5 0.0 2.6e-170 566.1 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 ETS73762.1 - 4.5e-80 267.5 0.0 9.7e-80 266.4 0.0 1.6 2 0 0 2 2 2 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 ETS73762.1 - 7.2e-80 267.2 0.0 1.1e-79 266.6 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain p450 PF00067.22 ETS73763.1 - 1.8e-43 149.0 0.0 2.2e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS73765.1 - 5.1e-52 177.2 0.0 7.5e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF3254 PF11630.8 ETS73766.1 - 0.052 13.7 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) Methyltransf_2 PF00891.18 ETS73767.1 - 2.6e-29 102.0 0.0 3.4e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 ETS73767.1 - 0.00012 22.7 0.0 0.00027 21.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS73767.1 - 0.0011 19.6 0.0 0.002 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS73767.1 - 0.011 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Fungal_trans PF04082.18 ETS73768.1 - 2.6e-05 23.4 0.8 8.5e-05 21.7 0.8 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS73768.1 - 3.7e-05 23.7 8.9 6e-05 23.1 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Anth_synt_I_N PF04715.13 ETS73768.1 - 0.071 13.3 0.0 0.29 11.3 0.0 2.0 1 1 1 2 2 2 0 Anthranilate synthase component I, N terminal region PhyH PF05721.13 ETS73769.1 - 4.7e-10 40.1 0.0 1e-09 39.0 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) FAD_binding_4 PF01565.23 ETS73771.1 - 2.5e-25 88.9 1.7 4.6e-25 88.0 1.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS73771.1 - 0.00095 19.2 0.4 0.0022 18.1 0.4 1.6 1 0 0 1 1 1 1 Berberine and berberine like Lactonase PF10282.9 ETS73772.1 - 1.9e-25 89.8 1.7 2.7e-25 89.4 1.7 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 ETS73772.1 - 0.00073 19.2 0.1 0.0025 17.4 0.0 1.7 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Glyco_hydro_35 PF01301.19 ETS73773.1 - 2.4e-81 273.8 0.6 3.9e-81 273.1 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 ETS73773.1 - 4.2e-59 199.4 0.5 6.7e-59 198.7 0.5 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 ETS73773.1 - 2.8e-57 192.2 7.0 2.5e-34 118.3 0.7 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 ETS73773.1 - 8.3e-20 70.2 0.3 1.9e-19 69.0 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Transferase PF02458.15 ETS73774.1 - 3e-13 49.3 0.0 2.9e-11 42.7 0.0 2.6 2 1 0 2 2 2 2 Transferase family DUF346 PF03984.13 ETS73775.1 - 3.9e-10 39.3 45.6 6.7e-05 22.6 2.1 7.6 7 1 0 7 7 7 5 Repeat of unknown function (DUF346) DUF551 PF04448.12 ETS73775.1 - 0.33 11.9 2.9 5.2 8.1 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF551) VCBS PF13517.6 ETS73775.1 - 3.3 8.4 8.7 0.97 10.1 0.8 3.4 3 2 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MAM33 PF02330.16 ETS73776.1 - 2e-72 243.6 3.4 2.5e-72 243.3 3.4 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein XPG_I PF00867.18 ETS73777.1 - 2.7e-22 78.9 0.0 5.9e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 ETS73777.1 - 6.8e-21 74.7 0.0 1.5e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 ETS73777.1 - 0.00033 20.2 0.0 0.0006 19.4 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 ETS73777.1 - 0.022 15.4 0.0 0.061 13.9 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 ETS73777.1 - 0.068 13.8 0.3 2 9.1 0.1 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain HTH_11 PF08279.12 ETS73777.1 - 0.072 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 HTH domain Tma16 PF11176.8 ETS73778.1 - 1.3e-46 158.1 0.5 1.5e-46 157.9 0.5 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 IBR PF01485.21 ETS73779.1 - 9.3e-23 80.2 45.5 3e-11 43.4 4.8 4.4 3 1 1 4 4 4 4 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 ETS73779.1 - 1.1e-07 31.6 39.3 3.9e-05 23.4 4.7 4.4 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ETS73779.1 - 6.9e-06 26.3 42.8 0.00014 22.1 6.9 3.9 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 ETS73779.1 - 0.00022 21.0 42.8 0.0004 20.2 5.2 4.9 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS73779.1 - 0.0056 16.7 33.4 0.021 14.8 4.7 3.9 3 1 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 ETS73779.1 - 0.015 15.5 29.6 0.045 13.9 1.1 4.5 3 2 0 3 3 3 0 zinc finger of C3HC4-type, RING UN_NPL4 PF11543.8 ETS73779.1 - 0.026 15.0 0.0 0.054 14.0 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-RING_14 PF17978.1 ETS73779.1 - 0.047 14.1 1.3 0.047 14.1 1.3 3.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain CobA_CobO_BtuR PF02572.15 ETS73779.1 - 0.15 12.3 0.2 0.38 11.0 0.2 1.6 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP zf-rbx1 PF12678.7 ETS73779.1 - 0.21 11.9 34.2 2.1 8.7 1.9 3.7 3 0 0 3 3 3 0 RING-H2 zinc finger domain Trp_syntA PF00290.20 ETS73779.1 - 0.22 10.4 0.0 0.36 9.6 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain MFS_1 PF07690.16 ETS73780.1 - 3.3e-34 118.4 54.1 3.3e-34 118.4 54.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS73780.1 - 1.3e-14 53.6 9.3 2.1e-14 52.9 9.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.18 ETS73781.1 - 5.1e-05 23.3 8.5 0.00012 22.1 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS73781.1 - 0.035 13.1 0.1 0.073 12.1 0.1 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Redoxin PF08534.10 ETS73782.1 - 1.7e-25 89.4 0.0 2.1e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ETS73782.1 - 1.4e-08 34.7 0.0 1.8e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Glyco_hydro_61 PF03443.14 ETS73783.1 - 7.7e-27 94.6 0.0 9.6e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PSDC PF12588.8 ETS73783.1 - 0.17 11.8 0.0 0.5 10.3 0.0 1.7 2 0 0 2 2 2 0 Phophatidylserine decarboxylase MFS_1 PF07690.16 ETS73784.1 - 5.6e-25 88.0 30.6 5.6e-25 88.0 30.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MAPEG PF01124.18 ETS73785.1 - 5.6e-17 61.9 1.1 6.4e-17 61.7 1.1 1.1 1 0 0 1 1 1 1 MAPEG family DUF167 PF02594.16 ETS73786.1 - 1.4e-24 86.0 1.3 3.4e-24 84.7 1.0 1.7 2 0 0 2 2 2 1 Uncharacterised ACR, YggU family COG1872 Methyltransf_34 PF11312.8 ETS73788.1 - 2e-79 267.0 0.0 2.4e-79 266.8 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase LIN37 PF15306.6 ETS73789.1 - 0.0081 16.4 0.5 3.8 7.7 0.0 2.1 2 0 0 2 2 2 2 LIN37 Arc PF03869.14 ETS73789.1 - 0.02 14.7 0.9 4.8 7.1 0.1 2.2 2 0 0 2 2 2 0 Arc-like DNA binding domain DUF4400 PF14348.6 ETS73789.1 - 0.024 14.1 2.2 0.028 13.9 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) DUF5350 PF17299.2 ETS73789.1 - 0.067 13.7 0.3 0.27 11.7 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5350) Glyco_hydro_47 PF01532.20 ETS73791.1 - 3.8e-168 560.1 0.0 4.6e-168 559.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ADH_N PF08240.12 ETS73792.1 - 3.9e-26 91.1 4.9 6.3e-26 90.4 4.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS73792.1 - 4.9e-16 58.9 0.0 4.4e-15 55.8 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS73792.1 - 0.00022 22.3 0.0 0.00041 21.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ETS73792.1 - 0.0038 16.5 0.0 0.0063 15.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ETS73792.1 - 0.0084 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF726 PF05277.12 ETS73792.1 - 0.084 11.8 0.4 0.14 11.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Adaptin_N PF01602.20 ETS73794.1 - 1.7e-135 452.6 3.6 2.3e-135 452.1 3.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ETS73794.1 - 1.9e-63 213.4 1.6 2.2e-61 206.6 0.1 2.9 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ETS73794.1 - 1.5e-16 60.6 0.4 9.9e-07 29.1 0.0 5.1 3 2 3 6 6 6 5 HEAT repeats HEAT PF02985.22 ETS73794.1 - 6.5e-11 41.5 5.6 0.021 15.0 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 ETS73794.1 - 6.9e-05 23.3 0.1 0.63 10.6 0.0 4.8 3 1 1 4 4 4 1 HEAT-like repeat UNC45-central PF11701.8 ETS73794.1 - 9.5e-05 22.4 0.2 0.025 14.5 0.0 2.6 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central RTP1_C1 PF10363.9 ETS73794.1 - 0.03 14.5 1.0 0.72 10.1 0.0 3.6 3 2 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 ETS73794.1 - 0.039 13.5 0.0 2 7.9 0.0 2.9 2 1 1 3 3 3 0 CLASP N terminal Atx10homo_assoc PF09759.9 ETS73794.1 - 0.065 13.3 0.0 5.7 7.0 0.0 3.2 2 1 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain RIX1 PF08167.12 ETS73794.1 - 0.068 12.9 0.1 14 5.4 0.0 2.9 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis DIOX_N PF14226.6 ETS73796.1 - 1.1e-28 100.3 0.0 1.8e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS73796.1 - 5.3e-18 65.4 0.0 1.4e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 ETS73797.1 - 1.1e-29 103.4 21.8 1.1e-29 103.4 21.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily PAS_9 PF13426.7 ETS73798.1 - 2.7e-19 69.4 0.0 2.2e-11 43.9 0.0 3.4 3 0 0 3 3 3 2 PAS domain GATA PF00320.27 ETS73798.1 - 7.6e-15 54.2 7.5 1.5e-14 53.3 7.5 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 ETS73798.1 - 6.7e-12 45.5 0.0 6.5e-08 32.8 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 ETS73798.1 - 2.5e-05 24.3 0.0 0.02 14.9 0.0 3.1 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 ETS73798.1 - 0.0004 20.6 0.0 0.21 11.9 0.0 3.2 3 0 0 3 3 3 1 PAS fold PAS_11 PF14598.6 ETS73798.1 - 0.0011 19.1 0.1 0.023 14.8 0.0 3.1 4 0 0 4 4 4 1 PAS domain DIOX_N PF14226.6 ETS73799.1 - 3.5e-24 85.8 0.0 5.4e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS73799.1 - 1.3e-20 73.8 0.0 2.4e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 ETS73799.1 - 0.16 12.9 0.0 0.26 12.2 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily SnoaL_4 PF13577.6 ETS73800.1 - 1.7e-09 37.8 0.6 2.2e-09 37.5 0.6 1.1 1 0 0 1 1 1 1 SnoaL-like domain Scytalone_dh PF02982.14 ETS73800.1 - 0.066 13.0 0.2 0.092 12.5 0.2 1.5 1 1 0 1 1 1 0 Scytalone dehydratase DUF4440 PF14534.6 ETS73800.1 - 0.077 13.4 0.7 0.19 12.2 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) MFS_1 PF07690.16 ETS73801.1 - 5.5e-17 61.7 42.4 5.5e-17 61.7 42.4 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS73801.1 - 0.00017 20.6 26.6 0.00017 20.6 6.4 3.6 1 1 2 3 3 3 3 Sugar (and other) transporter Fungal_trans_2 PF11951.8 ETS73802.1 - 0.00012 21.0 0.0 0.00021 20.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PHM7_cyt PF14703.6 ETS73802.1 - 0.0012 19.1 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter TMEM252 PF15664.5 ETS73804.1 - 0.051 13.3 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 252 family Tautomerase_3 PF14832.6 ETS73806.1 - 1.7e-15 57.5 0.1 2e-15 57.2 0.1 1.1 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.21 ETS73806.1 - 0.12 12.4 0.1 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Tautomerase enzyme BolA PF01722.18 ETS73807.1 - 2e-20 72.9 0.0 4.9e-20 71.6 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein NIF3 PF01784.18 ETS73808.1 - 2e-57 194.6 0.0 2.5e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Vps51 PF08700.11 ETS73809.1 - 5.5e-29 100.1 0.6 9.2e-29 99.4 0.1 1.7 2 0 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.12 ETS73809.1 - 0.00039 19.2 1.1 0.00052 18.8 1.1 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.9 ETS73809.1 - 0.04 14.1 0.3 0.075 13.2 0.3 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 RMI1_N PF08585.12 ETS73810.1 - 5.1e-56 189.8 0.0 5.9e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein COG5 PF10392.9 ETS73811.1 - 1e-38 132.5 2.0 1e-38 132.5 2.0 2.1 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Dor1 PF04124.12 ETS73811.1 - 0.026 13.2 0.4 0.049 12.3 0.4 1.5 1 0 0 1 1 1 0 Dor1-like family Peptidase_M41 PF01434.18 ETS73811.1 - 0.089 12.6 0.9 0.28 11.0 0.5 1.9 2 0 0 2 2 2 0 Peptidase family M41 MMTV_SAg PF01054.17 ETS73811.1 - 0.11 12.0 0.2 2.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Mouse mammary tumour virus superantigen LPP PF04728.13 ETS73811.1 - 0.56 10.6 3.6 0.54 10.7 1.1 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF4690 PF15756.5 ETS73813.1 - 0.02 15.5 4.4 0.02 15.5 4.4 2.4 1 1 1 2 2 2 0 Small Novel Rich in Cartilage DUF4448 PF14610.6 ETS73813.1 - 0.035 13.9 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Epiglycanin_C PF14654.6 ETS73813.1 - 0.038 14.0 0.0 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region RIFIN PF02009.16 ETS73813.1 - 0.046 13.6 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 Rifin Stevor PF17410.2 ETS73813.1 - 0.055 13.0 1.5 0.1 12.1 1.2 1.5 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame TMEM154 PF15102.6 ETS73813.1 - 2.2 8.2 14.3 0.035 14.0 1.4 2.4 1 1 1 2 2 2 0 TMEM154 protein family Sulfotransfer_4 PF17784.1 ETS73814.1 - 1.3e-54 185.3 0.0 1.5e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ETS73814.1 - 0.0024 18.3 0.1 0.0068 16.8 0.0 1.7 1 1 0 2 2 2 1 Sulfotransferase family Methyltransf_23 PF13489.6 ETS73815.1 - 1.4e-10 41.3 0.0 2.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS73815.1 - 5.8e-06 27.0 0.0 1.4e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS73815.1 - 2.7e-05 24.8 0.0 4.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 ETS73815.1 - 0.0075 15.8 0.0 0.023 14.2 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.9 ETS73815.1 - 0.01 15.6 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_11 PF08241.12 ETS73815.1 - 0.027 15.1 0.0 0.047 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CFEM PF05730.11 ETS73816.1 - 3.7e-12 46.2 10.1 5.9e-12 45.5 10.1 1.3 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.20 ETS73816.1 - 0.16 12.2 4.1 0.8 10.0 0.4 2.2 2 0 0 2 2 2 0 Gamma-thionin family FMN_dh PF01070.18 ETS73818.1 - 2.6e-102 342.4 0.1 1.5e-74 251.2 0.0 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ETS73818.1 - 1.6e-21 76.2 0.0 4.2e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 ETS73818.1 - 1.9e-08 33.8 0.1 3.2e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 ETS73818.1 - 4.4e-05 22.6 4.6 0.00018 20.6 1.7 2.5 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 ETS73818.1 - 0.00012 21.6 0.4 0.074 12.5 0.0 2.8 3 0 0 3 3 3 2 Histidine biosynthesis protein ThiG PF05690.14 ETS73818.1 - 0.0028 17.0 0.3 0.78 9.0 0.1 2.8 3 0 0 3 3 3 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 ETS73818.1 - 0.0036 16.4 0.6 0.071 12.2 0.0 2.2 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) NMO PF03060.15 ETS73818.1 - 0.013 14.9 0.1 0.027 13.9 0.1 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase DHO_dh PF01180.21 ETS73818.1 - 0.023 13.9 0.1 0.042 13.1 0.1 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 ETS73818.1 - 0.11 12.0 0.1 5.8 6.3 0.0 2.7 3 0 0 3 3 3 0 Glycerol-3-phosphate responsive antiterminator DUF561 PF04481.12 ETS73818.1 - 0.23 10.6 0.2 1.3 8.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Zn_clus PF00172.18 ETS73819.1 - 6e-05 23.1 12.5 0.00011 22.2 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS73819.1 - 0.00012 21.3 0.0 0.00018 20.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Laminin_EGF PF00053.24 ETS73819.1 - 0.12 12.5 10.1 0.3 11.2 10.1 1.6 1 0 0 1 1 1 0 Laminin EGF domain HET PF06985.11 ETS73820.1 - 4.2e-28 98.5 0.0 9.7e-28 97.3 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.29 ETS73821.1 - 1.5e-16 61.0 0.0 3.3e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS73821.1 - 0.00012 22.5 0.0 0.00035 21.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Zot PF05707.12 ETS73821.1 - 0.00099 18.8 0.0 0.014 15.1 0.0 2.5 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.6 ETS73821.1 - 0.0032 17.8 0.2 0.014 15.6 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 ETS73821.1 - 0.008 16.2 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 ETS73821.1 - 0.092 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A_type_inc PF04508.12 ETS73821.1 - 0.16 11.9 0.4 0.49 10.3 0.4 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Meiotic_rec114 PF03525.14 ETS73822.1 - 0.064 12.2 0.8 0.13 11.2 0.1 1.8 2 0 0 2 2 2 0 Meiotic recombination protein rec114 ATP-synt_B PF00430.18 ETS73822.1 - 1.6 8.9 7.8 0.17 12.0 2.6 2.1 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF4363 PF14276.6 ETS73822.1 - 9 6.5 12.4 22 5.2 0.7 5.0 4 1 1 5 5 5 0 Domain of unknown function (DUF4363) DUF365 PF04033.12 ETS73823.1 - 0.014 15.7 0.7 0.67 10.3 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF365) Fungal_trans_2 PF11951.8 ETS73824.1 - 1.5e-06 27.3 0.1 3.2e-06 26.2 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 ETS73824.1 - 0.00037 19.6 0.1 0.00055 19.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAF-AH_p_II PF03403.13 ETS73825.1 - 5.7e-17 61.3 0.0 1.5e-07 30.3 0.0 2.8 3 0 0 3 3 3 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ETS73825.1 - 5.1e-07 28.9 0.0 4e-06 25.9 0.0 2.2 1 1 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 ETS73825.1 - 2.1e-06 27.2 0.1 7.8e-06 25.3 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 ETS73825.1 - 8.9e-05 22.3 0.2 0.059 13.1 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 ETS73825.1 - 0.0013 19.4 1.0 0.0016 19.1 0.2 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS73825.1 - 0.0019 17.9 0.2 0.04 13.6 0.2 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 ETS73825.1 - 0.015 14.4 0.1 0.031 13.3 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase DUF4350 PF14258.6 ETS73825.1 - 0.09 13.2 0.1 0.44 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Lipase_3 PF01764.25 ETS73825.1 - 0.091 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Amidohydro_2 PF04909.14 ETS73826.1 - 1.7e-42 146.2 0.1 2.1e-42 145.9 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase HET PF06985.11 ETS73827.1 - 4.1e-13 49.9 0.0 1.7e-10 41.4 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) MAGI_u5 PF16666.5 ETS73827.1 - 0.0089 16.2 0.7 0.0089 16.2 0.7 1.6 2 0 0 2 2 2 1 Unstructured region on MAGI SKG6 PF08693.10 ETS73828.1 - 0.00075 18.9 0.2 0.002 17.5 0.2 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 ETS73828.1 - 2.1 8.3 6.2 8.4 6.4 6.2 2.1 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Hce2 PF14856.6 ETS73829.1 - 2.3e-14 53.5 0.0 3e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Esterase_phd PF10503.9 ETS73830.1 - 0.00038 20.0 0.0 0.001 18.6 0.0 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 ETS73830.1 - 0.0016 18.3 0.0 0.056 13.2 0.0 2.3 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 ETS73830.1 - 0.12 11.0 0.0 0.29 9.8 0.0 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) F-box-like PF12937.7 ETS73831.1 - 0.0007 19.4 0.4 0.0015 18.4 0.4 1.6 1 0 0 1 1 1 1 F-box-like PA PF02225.22 ETS73831.1 - 0.2 11.7 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 PA domain DUF3431 PF11913.8 ETS73832.1 - 7.8e-82 274.2 0.0 9.9e-82 273.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Glycophorin_A PF01102.18 ETS73833.1 - 0.0045 17.2 6.6 0.017 15.4 6.6 1.9 1 1 0 1 1 1 1 Glycophorin A Podoplanin PF05808.11 ETS73833.1 - 0.013 15.6 3.2 0.019 15.1 3.2 1.1 1 0 0 1 1 1 0 Podoplanin DUF4366 PF14283.6 ETS73833.1 - 0.015 15.4 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Amnionless PF14828.6 ETS73833.1 - 0.24 10.2 0.0 0.39 9.5 0.0 1.4 1 1 0 1 1 1 0 Amnionless SOG2 PF10428.9 ETS73833.1 - 0.25 10.5 8.3 0.27 10.4 8.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Shisa PF13908.6 ETS73833.1 - 6.7 6.9 11.4 1.3 9.2 0.1 2.2 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator p450 PF00067.22 ETS73834.1 - 2.8e-49 168.1 0.0 3.8e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Latarcin PF10279.9 ETS73834.1 - 0.031 14.7 0.1 9.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Latarcin precursor DUF2985 PF11204.8 ETS73835.1 - 1e-37 128.1 0.4 2.2e-37 127.1 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Glyco_hydro_106 PF17132.4 ETS73836.1 - 2e-23 82.7 0.0 5.1e-23 81.3 0.0 1.5 1 1 0 1 1 1 1 alpha-L-rhamnosidase Glyco_hydro_2_N PF02837.18 ETS73836.1 - 3.5e-05 23.8 0.0 7.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain COesterase PF00135.28 ETS73837.1 - 1.1e-82 278.6 0.0 1.4e-82 278.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS73837.1 - 3.2e-09 36.9 0.2 2.7e-08 34.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS73837.1 - 0.087 13.4 0.1 0.24 12.0 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Glyco_hydro_35 PF01301.19 ETS73838.1 - 5.1e-77 259.6 0.0 8.3e-77 258.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 ETS73838.1 - 5.4e-59 197.7 4.1 3e-31 108.3 0.1 3.9 4 0 0 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 ETS73838.1 - 1.1e-57 194.8 0.2 1.8e-57 194.1 0.2 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 ETS73838.1 - 1.1e-18 66.6 0.1 2.9e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Ebola_NP PF05505.12 ETS73838.1 - 0.096 11.0 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Fungal_trans PF04082.18 ETS73839.1 - 5.9e-14 51.7 0.1 1.1e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 ETS73840.1 - 1.2e-41 142.9 40.2 1.7e-41 142.3 38.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 ETS73840.1 - 1.8 6.8 10.4 1.3 7.2 2.3 3.2 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family adh_short PF00106.25 ETS73841.1 - 3.6e-37 127.7 0.0 4.7e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS73841.1 - 4.6e-27 95.1 0.0 6e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS73841.1 - 4.1e-12 46.4 0.0 5.6e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ETS73841.1 - 3.6e-05 23.7 0.0 4.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS73841.1 - 0.0011 18.5 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ETS73841.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Amidase PF01425.21 ETS73842.1 - 9.7e-94 314.9 0.0 1e-92 311.5 0.0 1.9 1 1 0 1 1 1 1 Amidase Zn_clus PF00172.18 ETS73843.1 - 1.3e-05 25.2 6.5 3.2e-05 24.0 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 ETS73844.1 - 1e-21 77.8 0.0 3.7e-20 72.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS73844.1 - 3.1e-15 57.4 0.6 4.9e-15 56.7 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS73844.1 - 3.3e-08 33.1 0.0 3e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 ETS73844.1 - 0.00016 20.5 0.0 0.00026 19.8 0.0 1.3 1 0 0 1 1 1 1 Ndr family ArabFuran-catal PF09206.11 ETS73845.1 - 1.2e-149 497.9 14.4 2e-149 497.1 14.4 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 ETS73845.1 - 8.5e-54 181.4 3.4 1.3e-53 180.7 3.4 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain CRAL_TRIO PF00650.20 ETS73846.1 - 2.5e-39 134.5 0.0 3.6e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ETS73846.1 - 1.2e-10 41.5 0.3 3.3e-10 40.0 0.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ETS73846.1 - 3.9e-05 23.8 0.0 6.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CUE PF02845.16 ETS73846.1 - 0.019 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 CUE domain Lipin_mid PF16876.5 ETS73846.1 - 0.16 12.1 0.0 7.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Lactonase PF10282.9 ETS73847.1 - 2.8e-07 30.1 0.5 3.1e-05 23.4 0.0 2.9 2 2 1 3 3 3 2 Lactonase, 7-bladed beta-propeller NHL PF01436.21 ETS73847.1 - 0.029 14.4 0.0 10 6.3 0.0 4.0 4 0 0 4 4 4 0 NHL repeat OTT_1508_deam PF14441.6 ETS73848.1 - 2e-20 72.5 0.0 3.9e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase YCII PF03795.14 ETS73849.1 - 0.0057 17.0 0.0 0.039 14.4 0.0 2.1 1 1 1 2 2 2 1 YCII-related domain Glyco_hydro_11 PF00457.17 ETS73850.1 - 2e-61 206.7 14.7 2.7e-61 206.3 14.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 zf-H2C2 PF09337.10 ETS73851.1 - 2.5e-14 53.2 0.4 5.4e-14 52.1 0.4 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 ETS73851.1 - 4.6e-13 49.1 0.1 9.5e-13 48.0 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 ETS73851.1 - 6.2e-05 23.2 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 ETS73851.1 - 0.0021 18.2 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ETS73851.1 - 0.0086 16.7 0.0 0.019 15.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS73851.1 - 0.11 13.0 0.0 0.55 10.7 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS73851.1 - 0.19 11.7 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fungal_trans_2 PF11951.8 ETS73852.1 - 1.6e-61 208.2 0.1 1.9e-61 208.0 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS73852.1 - 5.5e-09 36.0 10.0 1.1e-08 35.1 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PspB PF06667.12 ETS73852.1 - 0.093 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Phage shock protein B MFS_1 PF07690.16 ETS73853.1 - 1.4e-37 129.4 52.6 9.4e-36 123.5 52.6 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS73853.1 - 2.5e-12 46.1 20.0 6.4e-12 44.7 19.6 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 ETS73854.1 - 8.2e-07 28.1 0.0 1.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS73855.1 - 1.7e-59 201.8 0.0 2.3e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS73858.1 - 1.9e-15 56.6 0.1 4e-15 55.5 0.1 1.5 1 1 0 1 1 1 1 Cytochrome P450 Gaa1 PF04114.14 ETS73859.1 - 5.2 6.0 10.8 6.7 5.6 1.0 2.0 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component Peroxidase_2 PF01328.17 ETS73861.1 - 8.9e-44 150.3 0.0 1.2e-43 149.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 COBRA PF04833.15 ETS73863.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 COBRA-like protein adh_short PF00106.25 ETS73864.1 - 2.4e-29 102.2 0.6 6.6e-29 100.8 0.6 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS73864.1 - 7e-28 97.8 0.4 5.1e-26 91.7 0.4 2.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS73864.1 - 7.3e-08 32.5 0.2 1.5e-07 31.5 0.2 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS73864.1 - 0.0044 16.2 0.0 0.0068 15.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pkinase PF00069.25 ETS73865.1 - 6.1e-10 38.9 0.0 1.1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 ETS73865.1 - 0.0037 16.7 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ETS73865.1 - 0.0046 16.6 0.0 0.0083 15.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 ETS73865.1 - 0.013 15.5 1.0 0.062 13.2 0.8 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family CitX PF03802.14 ETS73865.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase Ribosomal_S26e PF01283.19 ETS73866.1 - 1.6e-52 176.4 9.6 1.9e-52 176.2 9.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 ETS73866.1 - 0.019 14.9 0.5 0.054 13.4 0.0 2.0 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 ETS73866.1 - 0.13 12.1 2.5 0.14 12.0 1.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4668) ubiquitin PF00240.23 ETS73867.1 - 4.4e-34 116.1 0.6 7.8e-34 115.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 ETS73867.1 - 2e-26 91.9 2.0 2e-26 91.9 2.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 ETS73867.1 - 2.6e-16 59.2 0.7 4.8e-16 58.3 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ETS73867.1 - 2.7e-05 24.5 0.4 0.00013 22.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 ETS73867.1 - 0.00071 19.7 0.7 0.0016 18.5 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 ETS73867.1 - 0.0041 17.4 0.9 0.0075 16.6 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 ETS73867.1 - 0.0054 16.6 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 ETS73867.1 - 0.012 16.1 0.9 0.018 15.6 0.9 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 ETS73867.1 - 0.02 14.9 1.0 5.8 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Glyco_hydro_18 PF00704.28 ETS73868.1 - 4.9e-92 309.0 0.1 5.6e-92 308.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GRA6 PF05084.13 ETS73869.1 - 0.0034 17.4 0.0 0.0075 16.2 0.0 1.5 1 1 0 1 1 1 1 Granule antigen protein (GRA6) Stevor PF17410.2 ETS73869.1 - 0.0084 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF1180 PF06679.12 ETS73869.1 - 0.018 15.4 0.3 0.031 14.7 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) TMEM154 PF15102.6 ETS73869.1 - 0.065 13.1 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF443 PF04276.12 ETS73869.1 - 0.12 12.1 0.1 0.54 10.0 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF443) DUF4148 PF13663.6 ETS73869.1 - 3.5 7.9 6.7 5.7 7.2 4.9 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4148) Insulin_TMD PF17870.1 ETS73870.1 - 0.017 15.2 0.3 0.017 15.2 0.3 1.6 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF1616 PF07760.11 ETS73870.1 - 0.4 10.0 4.6 0.94 8.8 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1616) Zn_clus PF00172.18 ETS73871.1 - 1.2e-09 38.1 12.5 1.9e-09 37.5 12.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS73871.1 - 1.8e-09 36.9 0.0 5e-09 35.5 0.0 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.13 ETS73872.1 - 2.1e-75 252.9 4.2 2.1e-75 252.9 4.2 1.8 1 1 1 2 2 2 1 RTA1 like protein Arginase PF00491.21 ETS73873.1 - 4.5e-76 256.0 0.1 5.2e-76 255.8 0.1 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.23 ETS73874.1 - 2.6e-06 27.5 16.5 4.2e-06 26.8 16.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.11 ETS73874.1 - 0.085 12.7 22.8 0.041 13.8 13.9 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF2070 PF09843.9 ETS73874.1 - 7.2 4.8 10.3 8.1 4.6 10.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Glyco_transf_90 PF05686.12 ETS73876.1 - 1e-13 51.0 1.9 1.3e-11 44.1 0.3 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 Ank_2 PF12796.7 ETS73878.1 - 3.5e-20 72.4 1.5 2.2e-10 41.0 0.6 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS73878.1 - 8.3e-16 58.1 9.1 1.5e-06 28.6 0.3 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS73878.1 - 1.5e-15 57.1 4.8 1.3e-05 25.3 0.1 4.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS73878.1 - 1.3e-14 52.8 4.5 0.001 19.4 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 ETS73878.1 - 3.4e-13 49.4 8.2 4.1e-05 23.8 0.2 4.3 4 0 0 4 4 4 3 Ankyrin repeat DUF1993 PF09351.10 ETS73880.1 - 2e-24 86.5 0.0 2.5e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF1479 PF07350.12 ETS73881.1 - 9.9e-163 541.7 0.0 1.1e-162 541.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 ETS73881.1 - 0.03 14.6 0.3 8 6.7 0.3 2.3 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.18 ETS73882.1 - 0.062 12.3 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS73882.1 - 0.095 12.8 5.7 0.17 12.0 5.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mrx7 PF10906.8 ETS73883.1 - 2e-07 31.2 0.0 3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 MIOREX complex component 7 But2 PF09792.9 ETS73885.1 - 2.4e-52 177.1 1.3 2.4e-52 177.1 1.3 4.8 2 1 3 6 6 6 1 Ubiquitin 3 binding protein But2 C-terminal domain Fungal_lectin PF07938.12 ETS73886.1 - 2.1e-08 33.9 6.5 2e-05 24.1 0.1 2.5 2 1 0 2 2 2 2 Fungal fucose-specific lectin Pilin_N PF07790.11 ETS73886.1 - 0.11 13.5 1.5 0.28 12.1 1.5 1.6 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal DUF4834 PF16118.5 ETS73886.1 - 0.22 12.5 0.0 0.44 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Bacteriocin_IIc PF10439.9 ETS73886.1 - 6.1 7.0 8.4 19 5.5 8.4 1.8 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DeoC PF01791.9 ETS73887.1 - 0.17 11.5 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 DeoC/LacD family aldolase SNF2_N PF00176.23 ETS73888.1 - 4.4e-07 28.9 0.0 6.4e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 ETS73888.1 - 9.8e-05 22.4 0.0 0.00015 21.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MFS_1 PF07690.16 ETS73889.1 - 1e-15 57.5 68.4 5.8e-12 45.2 36.6 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.12 ETS73890.1 - 4.1e-29 100.7 0.2 7e-29 99.9 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS73890.1 - 1.2e-22 80.3 0.0 1.8e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS73890.1 - 1e-09 39.6 0.1 1.6e-09 38.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS73890.1 - 3.4e-06 26.7 0.0 4.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 ETS73890.1 - 8.6e-06 26.0 0.0 1.6e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 ETS73890.1 - 0.00046 20.8 0.1 0.0008 20.0 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ADH_N_assoc PF13823.6 ETS73890.1 - 0.00074 19.4 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated NAD_binding_9 PF13454.6 ETS73890.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lyase_1 PF00206.20 ETS73890.1 - 0.22 10.9 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Lyase Reticulon PF02453.17 ETS73891.1 - 8.1e-15 55.1 0.8 1.2e-14 54.6 0.8 1.2 1 0 0 1 1 1 1 Reticulon MRP-S31 PF15433.6 ETS73891.1 - 0.07 12.8 3.7 0.11 12.2 3.7 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 RNA_pol_Rpb1_4 PF05000.17 ETS73891.1 - 0.25 11.3 3.0 0.74 9.8 3.0 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 DUF883 PF05957.13 ETS73891.1 - 0.26 11.9 3.7 7.2 7.3 3.3 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 ETS73891.1 - 0.53 10.8 6.9 2.8 8.5 6.9 2.3 1 1 0 1 1 1 0 YtxH-like protein GMC_oxred_C PF05199.13 ETS73892.1 - 1.3e-32 113.3 0.0 2.9e-32 112.2 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 ETS73892.1 - 7.2e-29 101.1 0.0 1.8e-19 70.3 0.0 3.1 3 0 0 3 3 3 3 GMC oxidoreductase NAD_binding_8 PF13450.6 ETS73892.1 - 0.00065 19.9 0.1 0.002 18.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS73892.1 - 0.0035 16.6 0.0 0.0053 16.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS73892.1 - 0.011 14.9 0.3 0.018 14.2 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 ETS73892.1 - 0.11 12.1 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 ETS73892.1 - 0.11 11.7 0.0 7.3 5.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 ETS73892.1 - 0.16 11.3 0.7 0.34 10.2 0.7 1.4 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.12 ETS73892.1 - 0.19 10.7 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 ETS73893.1 - 1.7e-31 109.7 0.0 2.4e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS73893.1 - 0.00016 21.4 0.2 0.18 11.3 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS73893.1 - 0.0013 18.0 0.3 1.4 8.0 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS73893.1 - 0.0039 17.4 0.1 0.01 16.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 ETS73893.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase HET PF06985.11 ETS73894.1 - 1.6e-20 74.0 0.2 3.2e-20 73.0 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GMC_oxred_N PF00732.19 ETS73895.1 - 4.4e-59 200.3 0.0 9.6e-59 199.2 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS73895.1 - 7.4e-35 120.6 0.0 1.1e-34 120.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS73895.1 - 1.3e-05 24.5 0.2 0.00036 19.8 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 ETS73895.1 - 0.021 14.4 2.8 1 8.9 2.8 2.5 2 1 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.18 ETS73895.1 - 0.049 13.9 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.6 ETS73895.1 - 0.085 13.1 0.3 0.22 11.8 0.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ETS73895.1 - 0.13 11.3 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF4360 PF14273.6 ETS73896.1 - 1.3e-66 223.9 8.2 1.4e-66 223.7 8.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Citrate_synt PF00285.21 ETS73897.1 - 1e-100 337.4 0.0 1.3e-100 337.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain ICL PF00463.21 ETS73898.1 - 1e-194 647.9 0.0 1.2e-194 647.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 ETS73898.1 - 2.8e-09 36.8 0.0 7.9e-09 35.3 0.0 1.8 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase adh_short_C2 PF13561.6 ETS73899.1 - 1.4e-59 201.5 0.2 1.6e-59 201.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS73899.1 - 2.3e-43 147.9 0.1 2.8e-43 147.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS73899.1 - 7.1e-11 42.3 1.1 1.1e-10 41.8 1.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS73899.1 - 7.3e-05 22.0 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 ETS73899.1 - 0.00054 20.6 0.0 0.0011 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.18 ETS73899.1 - 0.00093 19.1 0.1 0.0017 18.3 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_12 PF08242.12 ETS73899.1 - 0.015 16.0 0.0 0.041 14.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 ETS73899.1 - 0.016 14.8 0.1 0.032 13.8 0.1 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3Beta_HSD PF01073.19 ETS73899.1 - 0.033 13.2 0.1 0.093 11.7 0.0 1.7 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ETS73899.1 - 0.039 13.4 0.0 0.058 12.8 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.12 ETS73899.1 - 0.11 13.2 0.0 0.23 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Gln-synt_C PF00120.24 ETS73900.1 - 3.1e-83 279.6 0.0 3.7e-83 279.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 ETS73900.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain GDC-P PF02347.16 ETS73901.1 - 1.2e-173 577.9 0.0 2.2e-162 540.8 0.0 2.5 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 ETS73901.1 - 5.4e-08 32.2 0.1 0.002 17.1 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 ETS73901.1 - 2.9e-07 30.1 0.0 5.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 ETS73901.1 - 0.00014 20.5 0.0 0.011 14.3 0.0 2.3 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ETS73901.1 - 0.085 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family ProQ_C PF17516.2 ETS73901.1 - 0.19 11.2 1.9 0.34 10.4 0.1 2.1 2 0 0 2 2 2 0 ProQ C-terminal domain Nup54 PF13874.6 ETS73902.1 - 1.8e-37 128.6 0.5 1.8e-37 128.6 0.5 2.7 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 ETS73902.1 - 6.6e-06 25.6 10.7 1.2e-05 24.8 10.7 1.4 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain V-SNARE_C PF12352.8 ETS73902.1 - 0.011 16.0 0.2 1.3 9.4 0.1 2.7 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DivIVA PF05103.13 ETS73902.1 - 0.038 14.1 0.9 0.038 14.1 0.9 2.1 3 0 0 3 3 3 0 DivIVA protein MKRN1_C PF15815.5 ETS73902.1 - 0.04 14.3 0.4 0.15 12.5 0.4 2.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase makorin-1, C-terminal Ferritin PF00210.24 ETS73902.1 - 0.043 13.7 0.5 0.081 12.9 0.5 1.5 1 0 0 1 1 1 0 Ferritin-like domain FapA PF03961.13 ETS73902.1 - 0.061 11.9 1.0 0.1 11.2 0.9 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF5595 PF18077.1 ETS73902.1 - 0.13 12.4 4.9 0.11 12.6 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Nucleoporin_FG PF13634.6 ETS73902.1 - 0.23 12.3 20.5 0.43 11.5 20.5 1.4 1 0 0 1 1 1 0 Nucleoporin FG repeat region CHCH PF06747.13 ETS73903.1 - 6.8e-10 38.8 15.2 1.8e-08 34.3 6.3 2.5 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 ETS73903.1 - 9.8e-07 28.7 9.8 2.3e-05 24.3 5.1 2.2 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 ETS73903.1 - 0.00036 20.5 10.4 0.06 13.4 0.4 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 ETS73903.1 - 0.77 10.1 7.2 18 5.7 3.0 2.9 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Glyco_hydro_115 PF15979.5 ETS73904.1 - 4.8e-121 404.3 3.9 6.4e-121 403.9 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 ETS73904.1 - 1.6e-51 174.5 0.0 3.4e-51 173.5 0.0 1.6 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain S_layer_C PF05124.12 ETS73904.1 - 0.15 12.1 0.4 0.27 11.2 0.4 1.4 1 0 0 1 1 1 0 S-layer like family, C-terminal region PsiA PF06952.11 ETS73904.1 - 0.28 10.4 0.6 0.48 9.6 0.6 1.2 1 0 0 1 1 1 0 PsiA protein CAP PF00188.26 ETS73905.1 - 1.4e-14 55.0 5.7 1.4e-14 55.0 5.7 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Med13_C PF06333.12 ETS73905.1 - 0.27 10.5 6.4 0.36 10.1 6.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Glyco_hydro_28 PF00295.17 ETS73906.1 - 3.5e-95 318.8 19.0 4e-95 318.6 19.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Cadherin-like PF12733.7 ETS73906.1 - 4.3 7.9 6.6 0.89 10.1 0.2 2.9 3 1 0 3 3 3 0 Cadherin-like beta sandwich domain WD40 PF00400.32 ETS73907.1 - 3.8e-21 75.0 3.7 0.0012 19.6 0.0 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS73907.1 - 5.2e-08 33.1 0.0 0.2 11.9 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS73907.1 - 2.4e-05 23.4 0.4 0.83 8.5 0.0 4.0 3 2 0 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein ADH_zinc_N PF00107.26 ETS73908.1 - 9.6e-22 77.3 3.0 2.4e-21 76.1 0.4 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS73908.1 - 8.5e-21 73.9 5.1 1.5e-20 73.1 5.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ETS73908.1 - 0.00047 21.2 0.4 0.00089 20.3 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_32 PF13679.6 ETS73908.1 - 0.0012 18.9 1.3 0.0048 16.9 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 ETS73908.1 - 0.002 17.7 0.1 0.0037 16.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain HAD_2 PF13419.6 ETS73909.1 - 2.1e-22 80.1 0.0 2.9e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETS73909.1 - 5.6e-11 43.1 0.0 2.5e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ETS73909.1 - 2.3e-07 30.7 0.0 3.7e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 HAD-hyrolase-like HAD PF12710.7 ETS73909.1 - 0.0001 22.7 0.0 0.00016 22.1 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ETS73909.1 - 0.0012 18.9 0.0 0.0037 17.3 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase SCAN PF02023.17 ETS73909.1 - 0.16 11.8 0.3 0.87 9.4 0.0 2.1 2 0 0 2 2 2 0 SCAN domain Glyco_hydro_16 PF00722.21 ETS73910.1 - 5.7e-38 130.2 5.4 8.8e-38 129.5 5.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TP_methylase PF00590.20 ETS73911.1 - 1.3e-46 159.3 0.1 2.4e-46 158.4 0.1 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_M PF14824.6 ETS73911.1 - 8.1e-12 44.4 0.1 1.9e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.6 ETS73911.1 - 3.7e-11 43.4 0.0 7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 ETS73911.1 - 4.9e-09 35.7 0.0 1.5e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Asp PF00026.23 ETS73912.1 - 1.6e-09 37.6 0.1 2.7e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease VSP PF03302.13 ETS73912.1 - 0.0011 18.0 0.6 0.0019 17.1 0.6 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein CYYR1 PF10873.8 ETS73912.1 - 0.043 14.3 0.2 0.093 13.2 0.2 1.5 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Amnionless PF14828.6 ETS73912.1 - 0.06 12.2 0.0 0.14 11.0 0.0 1.5 2 0 0 2 2 2 0 Amnionless Syndecan PF01034.20 ETS73912.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DUF4646 PF15496.6 ETS73914.1 - 0.0031 18.1 0.0 0.0061 17.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) SH3_1 PF00018.28 ETS73917.1 - 4.7e-09 35.7 0.1 8.5e-09 34.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ETS73917.1 - 1.6e-06 27.9 0.0 2.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ETS73917.1 - 1.3e-05 24.8 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 ETS73917.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 SH3 domain MerC PF03203.14 ETS73917.1 - 3.2 8.2 8.6 5.9 7.4 8.6 1.4 1 1 0 1 1 1 0 MerC mercury resistance protein Dynactin_p22 PF07426.11 ETS73918.1 - 2.4e-06 27.5 0.4 3.5e-06 27.0 0.1 1.3 2 0 0 2 2 2 1 Dynactin subunit p22 TolA_bind_tri PF16331.5 ETS73918.1 - 0.24 11.5 4.6 21 5.3 0.3 3.6 3 1 0 3 3 3 0 TolA binding protein trimerisation Aa_trans PF01490.18 ETS73919.1 - 7.4e-93 311.5 13.0 9.8e-93 311.1 13.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 ETS73919.1 - 1.8e-05 23.9 18.1 1.8e-05 23.9 18.1 1.5 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Abhydrolase_9_N PF15420.6 ETS73919.1 - 0.091 12.8 0.2 0.091 12.8 0.2 2.6 4 0 0 4 4 4 0 Alpha/beta-hydrolase family N-terminus TauD PF02668.16 ETS73920.1 - 2.2e-45 155.6 0.5 2.8e-45 155.2 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ax_dynein_light PF10211.9 ETS73920.1 - 0.013 15.5 0.1 0.029 14.3 0.1 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain DASH_Spc19 PF08287.11 ETS73921.1 - 1.5e-46 158.1 0.0 2.4e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Spc19 DUF3584 PF12128.8 ETS73921.1 - 0.0013 16.3 1.8 0.0016 16.1 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) COG5 PF10392.9 ETS73921.1 - 0.021 15.0 1.9 5.1 7.3 0.3 3.0 2 1 0 3 3 3 0 Golgi transport complex subunit 5 Surfac_D-trimer PF09006.11 ETS73921.1 - 0.11 12.4 0.4 4.1 7.4 0.1 2.7 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Prefoldin_2 PF01920.20 ETS73921.1 - 0.18 11.8 4.7 11 6.0 4.9 2.3 2 0 0 2 2 2 0 Prefoldin subunit Nbl1_Borealin_N PF10444.9 ETS73921.1 - 0.2 11.3 5.5 1.4 8.7 0.9 2.6 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal TRAM_LAG1_CLN8 PF03798.16 ETS73922.1 - 1e-43 149.4 15.3 1.8e-43 148.6 15.3 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 ETS73922.1 - 4.5e-20 71.1 0.0 1.2e-19 69.7 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein Bax1-I PF01027.20 ETS73923.1 - 1.7e-52 178.3 25.2 1.9e-52 178.1 25.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Septin PF00735.18 ETS73924.1 - 1.6e-107 359.0 0.1 3.4e-107 357.9 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 ETS73924.1 - 5e-05 23.4 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ETS73924.1 - 0.0042 17.2 4.4 1.7 8.7 0.0 3.1 2 1 1 3 3 3 2 Dynamin family AAA_33 PF13671.6 ETS73924.1 - 0.017 15.3 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ETS73924.1 - 0.023 14.6 0.5 0.023 14.6 0.5 2.3 2 1 0 2 2 2 0 RsgA GTPase EB1 PF03271.17 ETS73924.1 - 0.054 13.7 1.5 1.8 8.9 1.3 2.6 2 0 0 2 2 2 0 EB1-like C-terminal motif IIGP PF05049.13 ETS73924.1 - 0.076 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) GTP_EFTU PF00009.27 ETS73924.1 - 0.11 12.0 1.8 0.2 11.2 0.1 2.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 ETS73924.1 - 0.25 11.6 1.5 0.38 11.0 0.1 2.1 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 ETS73924.1 - 0.26 10.6 0.1 0.26 10.6 0.1 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 ETS73924.1 - 0.35 11.3 4.4 13 6.2 3.7 2.2 2 0 0 2 2 2 0 AAA domain Ribosomal_S17e PF00833.18 ETS73924.1 - 0.61 10.0 4.2 1.5 8.8 4.2 1.6 1 0 0 1 1 1 0 Ribosomal S17 WD40 PF00400.32 ETS73925.1 - 1.3e-07 32.2 0.0 0.03 15.2 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS73925.1 - 1.1e-05 25.7 0.0 0.2 12.0 0.0 3.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 ETS73925.1 - 0.028 12.4 0.0 0.04 11.9 0.0 1.3 1 0 0 1 1 1 0 IKI3 family Ge1_WD40 PF16529.5 ETS73925.1 - 0.034 13.1 0.1 1.7 7.6 0.0 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 ETS73925.1 - 0.13 11.6 0.1 0.29 10.4 0.0 1.5 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal RRM_1 PF00076.22 ETS73926.1 - 1.1e-13 50.8 0.2 3e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ETS73926.1 - 0.0062 16.6 0.0 0.076 13.1 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif DLIC PF05783.11 ETS73927.1 - 1.6e-37 129.5 0.1 4.9e-37 127.9 0.0 1.8 2 1 0 2 2 2 1 Dynein light intermediate chain (DLIC) Thioredox_DsbH PF03190.15 ETS73928.1 - 9.2e-52 175.3 0.0 1.7e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 ETS73928.1 - 0.00032 20.8 0.0 0.0011 19.1 0.0 2.0 1 0 0 1 1 1 1 Thioredoxin-like GlcNAc_2-epim PF07221.11 ETS73928.1 - 0.021 14.1 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_76 PF03663.14 ETS73928.1 - 0.033 13.7 0.6 0.1 12.1 0.2 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 DUF2193 PF09959.9 ETS73928.1 - 0.077 11.4 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) Peptidase_S10 PF00450.22 ETS73929.1 - 2.3e-78 264.5 0.1 3.2e-78 264.0 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S9 PF00326.21 ETS73929.1 - 0.018 14.6 0.3 0.12 11.8 0.2 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family MAM PF00629.23 ETS73930.1 - 0.00081 19.4 0.0 0.0023 17.9 0.0 1.7 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu DUF4918 PF16265.5 ETS73930.1 - 0.07 12.6 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4918) PPIP5K2_N PF18086.1 ETS73931.1 - 0.024 14.8 0.0 0.05 13.8 0.0 1.6 1 0 0 1 1 1 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain Gas_vesicle_C PF01304.17 ETS73931.1 - 0.027 14.5 1.1 0.19 11.8 0.5 2.4 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain DUF2314 PF10077.9 ETS73931.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2314) Fungal_trans PF04082.18 ETS73932.1 - 4.5e-15 55.4 0.6 6.4e-15 54.9 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS73932.1 - 5.5e-09 36.0 10.2 1.1e-08 35.0 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 ETS73933.1 - 5.6e-85 285.8 0.0 7.7e-85 285.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 ETS73933.1 - 1.1e-27 97.1 0.0 1.8e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ETS73933.1 - 5.9e-23 81.7 0.0 1.4e-22 80.5 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ETS73933.1 - 6.9e-12 46.0 0.0 1.9e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 ETS73933.1 - 0.021 15.1 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_NdrI PF07972.11 ETS73933.1 - 0.1 12.7 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 NrdI Flavodoxin like FMN_red PF03358.15 ETS73933.1 - 0.11 12.2 0.0 12 5.6 0.0 2.7 1 1 1 2 2 2 0 NADPH-dependent FMN reductase PG_isomerase_N PF18353.1 ETS73933.1 - 0.11 12.9 0.0 0.49 10.8 0.0 2.1 1 0 0 1 1 1 0 Phosphoglucose isomerase N-terminal domain MPC PF03650.13 ETS73934.1 - 8.1e-49 164.4 0.4 1.2e-48 163.8 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Herpes_glycop PF01528.16 ETS73934.1 - 0.0056 15.6 0.0 0.0078 15.1 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus glycoprotein M L51_S25_CI-B8 PF05047.16 ETS73935.1 - 4.1e-12 45.8 0.0 5.2e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain CaM_binding PF07839.11 ETS73935.1 - 0.11 13.3 0.0 0.13 13.0 0.0 1.1 1 0 0 1 1 1 0 Plant calmodulin-binding domain RRM_1 PF00076.22 ETS73936.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-Tim10_DDP PF02953.15 ETS73936.1 - 0.11 12.2 0.3 0.28 10.8 0.3 1.6 1 0 0 1 1 1 0 Tim10/DDP family zinc finger DUF1687 PF07955.11 ETS73937.1 - 3.2e-33 114.9 0.2 4.2e-33 114.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) GST_N_2 PF13409.6 ETS73937.1 - 0.076 13.3 0.0 0.18 12.1 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain IMD PF08397.11 ETS73939.1 - 1.1e-05 24.9 2.5 8.7e-05 22.0 2.5 1.9 1 1 0 1 1 1 1 IRSp53/MIM homology domain Seryl_tRNA_N PF02403.22 ETS73939.1 - 0.07 13.4 0.8 0.16 12.2 0.6 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TMCO5 PF14992.6 ETS73939.1 - 0.18 11.4 1.4 0.26 10.8 1.4 1.2 1 0 0 1 1 1 0 TMCO5 family LYTB PF02401.18 ETS73939.1 - 0.22 10.8 0.2 0.55 9.4 0.0 1.7 2 0 0 2 2 2 0 LytB protein UPF0242 PF06785.11 ETS73939.1 - 0.36 10.9 2.0 0.55 10.3 2.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FAD_binding_3 PF01494.19 ETS73940.1 - 4.9e-22 78.6 0.0 1.7e-21 76.8 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS73940.1 - 3.4e-07 30.2 0.5 1.2e-06 28.4 0.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS73940.1 - 8.6e-06 25.2 4.0 0.0013 18.0 1.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS73940.1 - 0.00015 21.9 4.2 0.00032 20.9 0.9 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 ETS73940.1 - 0.0019 17.3 0.0 0.0035 16.5 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 ETS73940.1 - 0.0069 15.3 0.7 0.33 9.8 0.5 2.8 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 ETS73940.1 - 0.012 16.1 3.1 0.033 14.8 1.3 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS73940.1 - 0.03 13.4 2.3 0.048 12.7 2.3 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 ETS73940.1 - 0.13 11.3 0.3 0.17 10.9 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ETS73940.1 - 0.17 11.2 0.4 0.27 10.5 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 ETS73940.1 - 0.25 10.3 2.3 2.9 6.9 2.3 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein Ferric_reduct PF01794.19 ETS73942.1 - 0.0071 16.5 5.2 0.0071 16.5 5.2 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component AMP-binding PF00501.28 ETS73943.1 - 6e-71 239.3 0.0 7.2e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS73943.1 - 9.7e-15 55.3 0.0 2.3e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hydrolase_like PF13242.6 ETS73944.1 - 0.00031 20.8 0.0 0.00057 19.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ETS73944.1 - 0.016 15.5 0.0 0.058 13.7 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Dioxygenase_C PF00775.21 ETS73945.1 - 1.2e-40 138.9 0.0 1.7e-40 138.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 ETS73945.1 - 1.9e-25 88.5 0.1 3.2e-25 87.8 0.1 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 ETS73945.1 - 0.028 14.7 0.0 0.11 12.8 0.0 1.9 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain SpaA PF17802.1 ETS73945.1 - 0.031 14.6 0.0 0.07 13.5 0.0 1.6 1 0 0 1 1 1 0 Prealbumin-like fold domain Glyco_hydro_10 PF00331.20 ETS73946.1 - 3.5e-105 351.6 0.0 4e-105 351.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 GYF_2 PF14237.6 ETS73946.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 GYF domain 2 Glyco_hydro_62 PF03664.13 ETS73947.1 - 1.2e-58 198.6 13.1 1.4e-58 198.4 13.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 AltA1 PF16541.5 ETS73948.1 - 6.4e-12 46.3 0.0 8.2e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Alternaria alternata allergen 1 GDPD_2 PF13653.6 ETS73949.1 - 0.00049 20.5 0.7 0.0013 19.1 0.7 1.8 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family zf-MYND PF01753.18 ETS73950.1 - 0.00028 20.9 4.4 0.00028 20.9 4.4 2.0 2 0 0 2 2 2 1 MYND finger Ecl1 PF12855.7 ETS73950.1 - 0.0053 17.9 2.7 0.0087 17.2 2.7 1.3 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-HIT PF04438.16 ETS73950.1 - 0.01 15.7 4.3 0.018 14.9 4.3 1.4 1 0 0 1 1 1 0 HIT zinc finger Methyltrn_RNA_3 PF02598.17 ETS73951.1 - 1.6e-94 316.7 0.0 1.8e-94 316.4 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Thioredoxin PF00085.20 ETS73952.1 - 2.1e-28 98.3 0.0 2.8e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ETS73952.1 - 8.1e-06 26.3 0.1 4.2e-05 23.9 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 ETS73952.1 - 0.00012 21.5 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 ETS73952.1 - 0.00032 20.4 0.1 0.24 11.1 0.0 2.2 1 1 1 2 2 2 2 Redoxin Thioredoxin_8 PF13905.6 ETS73952.1 - 0.00034 20.9 0.0 0.00079 19.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.16 ETS73952.1 - 0.00076 18.5 0.3 0.0091 15.0 0.0 2.0 2 0 0 2 2 2 1 Phosducin AhpC-TSA PF00578.21 ETS73952.1 - 0.0019 18.1 0.1 0.0041 17.0 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 ETS73952.1 - 0.0028 17.4 0.0 0.0039 17.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 ETS73952.1 - 0.033 14.4 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 ETS73952.1 - 0.2 11.7 0.0 0.44 10.5 0.0 1.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Rsm22 PF09243.10 ETS73953.1 - 2.9e-33 115.3 0.0 1.1e-31 110.2 0.0 2.7 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 ETS73953.1 - 0.00052 19.9 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS73953.1 - 0.12 13.1 0.0 0.82 10.4 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Radial_spoke PF04712.12 ETS73953.1 - 1.3 7.8 9.2 2.5 6.9 9.2 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein Melibiase_2 PF16499.5 ETS73955.1 - 3.9e-13 49.2 2.6 4.3e-08 32.7 0.0 2.2 1 1 1 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 ETS73955.1 - 6.9e-09 35.7 0.2 1.6e-08 34.5 0.2 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Fungal_trans PF04082.18 ETS73956.1 - 3.1e-06 26.4 0.0 5.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Bac_rhamnosid6H PF17389.2 ETS73957.1 - 7.7e-92 308.1 0.2 1e-91 307.7 0.2 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 ETS73957.1 - 4.5e-54 182.8 0.0 8.1e-54 182.0 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 ETS73957.1 - 1.1e-16 60.7 0.0 2e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 ETS73957.1 - 7.1e-14 51.4 0.0 1.9e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Sugar_tr PF00083.24 ETS73958.1 - 1.1e-102 344.3 25.0 1.3e-102 344.0 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS73958.1 - 4.6e-26 91.6 35.8 1.9e-25 89.6 28.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 ETS73958.1 - 0.00014 21.0 0.5 0.00014 21.0 0.5 2.3 3 0 0 3 3 3 1 Sugar-tranasporters, 12 TM DUF948 PF06103.11 ETS73959.1 - 0.0026 18.0 0.4 0.0066 16.7 0.4 1.7 2 0 0 2 2 1 1 Bacterial protein of unknown function (DUF948) Dor1 PF04124.12 ETS73959.1 - 0.0052 15.5 1.1 0.007 15.1 1.1 1.1 1 0 0 1 1 1 1 Dor1-like family MCPsignal PF00015.21 ETS73959.1 - 0.012 15.4 2.2 0.023 14.5 1.9 1.6 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain BLOC1_2 PF10046.9 ETS73959.1 - 0.021 15.1 0.9 0.59 10.5 0.3 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3818 PF12825.7 ETS73959.1 - 0.03 13.3 0.6 0.041 12.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Spc24 PF08286.11 ETS73959.1 - 0.038 14.2 0.2 0.07 13.4 0.2 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Vps5 PF09325.10 ETS73959.1 - 0.038 13.5 0.3 0.094 12.2 0.3 1.6 1 1 0 1 1 1 0 Vps5 C terminal like Snapin_Pallidin PF14712.6 ETS73959.1 - 0.04 14.4 0.1 0.22 12.0 0.1 1.8 1 1 1 2 2 2 0 Snapin/Pallidin BORCS8 PF10167.9 ETS73959.1 - 0.061 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 AI-2E_transport PF01594.16 ETS73959.1 - 0.072 12.2 2.5 0.1 11.7 2.5 1.2 1 0 0 1 1 1 0 AI-2E family transporter DivIC PF04977.15 ETS73959.1 - 0.072 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator HSBP1 PF06825.12 ETS73959.1 - 0.11 12.4 3.8 0.67 9.9 2.0 2.7 1 1 1 2 2 2 0 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.12 ETS73959.1 - 0.12 12.5 22.6 0.12 12.5 11.7 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin_2 PF14523.6 ETS73959.1 - 0.13 12.6 2.6 0.4 11.1 2.4 1.9 1 1 0 1 1 1 0 Syntaxin-like protein DUF5082 PF16888.5 ETS73959.1 - 0.14 12.4 5.0 0.098 12.9 2.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) BAR_3 PF16746.5 ETS73959.1 - 0.15 11.7 0.1 0.22 11.2 0.1 1.1 1 0 0 1 1 1 0 BAR domain of APPL family LXG PF04740.12 ETS73959.1 - 0.15 11.7 2.1 0.44 10.2 2.0 1.7 1 1 1 2 2 2 0 LXG domain of WXG superfamily Syntaxin-6_N PF09177.11 ETS73959.1 - 0.22 12.1 0.5 1.6 9.4 0.5 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4988 PF16378.5 ETS73959.1 - 0.33 10.6 2.7 0.81 9.3 2.7 1.6 1 0 0 1 1 1 0 Domain of unknown function NUMOD1 PF07453.13 ETS73959.1 - 0.46 10.8 7.9 2.6 8.4 0.5 4.1 1 1 3 4 4 4 0 NUMOD1 domain Fib_alpha PF08702.10 ETS73959.1 - 0.53 10.5 1.8 1 9.6 1.8 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family YvrJ PF12841.7 ETS73959.1 - 0.59 9.7 3.5 5.9 6.5 0.1 3.5 3 1 3 6 6 6 0 YvrJ protein family LOH1CR12 PF10158.9 ETS73959.1 - 1.1 9.3 3.8 4 7.5 3.8 1.8 1 1 0 1 1 1 0 Tumour suppressor protein DUF1241 PF06840.11 ETS73959.1 - 1.4 8.6 3.7 18 5.0 3.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1241) DUF3130 PF11328.8 ETS73959.1 - 2 8.7 5.9 1.5 9.1 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3130 DASH_Spc19 PF08287.11 ETS73959.1 - 7.4 6.4 5.5 1.3 8.9 1.1 2.0 2 0 0 2 2 2 0 Spc19 YjeF_N PF03853.15 ETS73960.1 - 2.5e-34 118.6 0.0 3.1e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus SL4P PF17618.2 ETS73960.1 - 0.14 12.3 0.0 0.42 10.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein DprA_WH PF17782.1 ETS73960.1 - 0.19 11.9 0.1 0.48 10.6 0.1 1.6 1 0 0 1 1 1 0 DprA winged helix domain Ribosomal_S16 PF00886.19 ETS73961.1 - 1.9e-26 91.9 0.0 7.7e-26 89.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S16 CPSase_L_D2 PF02786.17 ETS73962.1 - 6.5e-72 241.4 0.0 1.3e-71 240.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 ETS73962.1 - 6.8e-39 132.3 0.0 1.6e-38 131.1 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 ETS73962.1 - 5.9e-37 126.6 0.0 1.2e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 ETS73962.1 - 8.3e-15 54.4 1.8 8.3e-15 54.4 1.8 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ETS73962.1 - 4.1e-06 26.5 0.3 0.031 14.1 0.0 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 ETS73962.1 - 4.5e-06 27.3 0.4 0.2 12.4 0.0 3.1 3 0 0 3 3 2 2 HlyD family secretion protein Dala_Dala_lig_C PF07478.13 ETS73962.1 - 5.2e-05 22.9 0.0 0.00017 21.2 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 ETS73962.1 - 0.0015 18.6 0.0 0.0034 17.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 ETS73962.1 - 0.0049 16.1 0.2 1.7 7.8 0.0 3.0 2 1 1 3 3 3 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 ETS73962.1 - 0.0069 16.0 0.0 0.061 12.9 0.0 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain LAL_C2 PF18603.1 ETS73962.1 - 0.013 15.7 0.1 0.076 13.2 0.0 2.4 3 0 0 3 3 3 0 L-amino acid ligase C-terminal domain 2 ATPgrasp_ST PF14397.6 ETS73962.1 - 0.088 12.0 0.0 0.39 9.9 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Putative_PNPOx PF01243.20 ETS73963.1 - 2.3e-13 50.2 0.0 1.1e-12 48.0 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 ETS73963.1 - 0.00035 20.6 0.0 0.0091 16.0 0.0 2.2 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Gpi16 PF04113.14 ETS73963.1 - 0.032 12.7 0.2 0.034 12.6 0.2 1.1 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component Peroxidase_2 PF01328.17 ETS73964.1 - 4.7e-52 177.2 0.0 5.8e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 B_solenoid_ydck PF18836.1 ETS73964.1 - 0.057 13.3 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Beta solenoid repeat from YDCK Zn_clus PF00172.18 ETS73965.1 - 7.1e-08 32.5 9.4 1.3e-07 31.6 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS73965.1 - 3e-07 29.8 0.0 7.4e-07 28.5 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 ETS73966.1 - 5.4e-29 101.2 43.0 1.1e-27 96.9 15.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Peptidase_S10 PF00450.22 ETS73967.1 - 1.5e-104 350.7 4.6 1.9e-104 350.4 4.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase adh_short PF00106.25 ETS73968.1 - 9.7e-33 113.3 0.2 7.5e-32 110.4 0.0 2.2 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS73968.1 - 1.1e-24 87.3 0.1 6.8e-24 84.7 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS73968.1 - 1.6e-07 31.4 0.1 2.3e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS73968.1 - 5.1e-05 22.8 0.3 0.00019 21.0 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS73968.1 - 0.0002 20.9 0.4 0.00075 19.0 0.4 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Fungal_trans PF04082.18 ETS73969.1 - 0.00036 19.6 0.3 0.00085 18.4 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain RRM_1 PF00076.22 ETS73972.1 - 2.2e-24 85.0 0.0 1.2e-13 50.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PCI PF01399.27 ETS73974.1 - 7.7e-21 74.6 0.1 4.8e-20 72.0 0.0 2.4 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 ETS73974.1 - 3.6e-16 59.0 2.8 8.9e-16 57.7 2.8 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain FSH1 PF03959.13 ETS73975.1 - 1.3e-64 217.8 0.0 1.6e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 ETS73975.1 - 4.6e-05 23.2 0.1 0.24 11.0 0.1 2.4 2 1 1 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS73975.1 - 0.00051 19.4 0.0 0.016 14.5 0.0 2.4 3 0 0 3 3 3 1 Serine aminopeptidase, S33 His_Phos_1 PF00300.22 ETS73975.1 - 0.0031 17.2 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DLH PF01738.18 ETS73975.1 - 0.0059 16.2 0.0 3.6 7.1 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 ETS73975.1 - 0.023 14.5 0.9 0.73 9.6 0.9 2.8 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 ETS73975.1 - 0.029 14.5 0.1 0.053 13.6 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain Esterase_phd PF10503.9 ETS73975.1 - 0.066 12.7 0.6 0.69 9.4 1.0 2.3 2 1 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 ETS73975.1 - 0.076 13.6 4.9 0.18 12.4 4.9 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Chorion_S16 PF05836.12 ETS73975.1 - 0.19 11.9 1.0 0.28 11.4 0.0 1.7 2 0 0 2 2 2 0 Chorion protein S16 ATP-synt_J PF04911.12 ETS73976.1 - 2.8e-25 87.6 4.1 5.2e-19 67.6 0.2 2.1 2 0 0 2 2 2 2 ATP synthase j chain NIPSNAP PF07978.13 ETS73977.1 - 6.3e-41 138.7 0.3 5.1e-29 100.5 0.1 2.5 2 0 0 2 2 2 2 NIPSNAP Rogdi_lz PF10259.9 ETS73978.1 - 7.9e-92 307.5 0.0 9.2e-92 307.3 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rpp20 PF12328.8 ETS73979.1 - 5.3e-22 78.3 0.0 8.3e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 ETS73979.1 - 1.5e-08 34.3 0.0 3.7e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 Alba Acetyltransf_7 PF13508.7 ETS73979.1 - 0.017 15.5 0.5 0.054 13.9 0.0 2.0 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS73979.1 - 0.019 15.2 0.0 0.048 13.9 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Abhydrolase_6 PF12697.7 ETS73980.1 - 2.3e-13 51.3 3.2 2.9e-13 50.9 3.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS73980.1 - 4.5e-12 45.7 0.4 2.3e-11 43.4 0.2 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS73980.1 - 5.6e-06 26.2 0.1 4e-05 23.4 0.7 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 ETS73980.1 - 0.023 13.6 0.0 0.023 13.6 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 ETS73980.1 - 0.024 13.7 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_5 PF12695.7 ETS73980.1 - 0.071 12.9 0.1 3.3 7.4 0.1 2.7 3 0 0 3 3 3 0 Alpha/beta hydrolase family Flu_M1 PF00598.19 ETS73980.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) Lipase_3 PF01764.25 ETS73980.1 - 0.14 12.0 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF3089 PF11288.8 ETS73980.1 - 0.21 11.1 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) NACHT PF05729.12 ETS73983.1 - 1.1e-08 35.1 0.0 3e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS73983.1 - 3e-05 24.5 0.4 0.00098 19.5 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS73983.1 - 0.00022 21.5 0.0 0.0016 18.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ETS73983.1 - 0.00033 21.0 0.1 0.0018 18.6 0.1 2.4 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 ETS73983.1 - 0.00064 19.7 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 ETS73983.1 - 0.00092 19.6 0.0 0.011 16.1 0.0 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ETS73983.1 - 0.0036 17.2 0.5 0.055 13.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 ETS73983.1 - 0.0073 16.9 0.0 0.023 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 ETS73983.1 - 0.0075 15.5 0.6 0.015 14.5 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.27 ETS73983.1 - 0.0079 16.7 0.5 0.026 15.0 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 ETS73983.1 - 0.009 15.7 1.2 0.054 13.2 0.1 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ETS73983.1 - 0.035 14.2 0.0 0.16 12.1 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF2408 PF10303.9 ETS73983.1 - 0.053 14.1 0.9 0.22 12.1 0.8 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF2408) Ploopntkinase3 PF18751.1 ETS73983.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 DUF2383 PF09537.10 ETS73983.1 - 0.062 13.7 0.3 5.7 7.3 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) Sigma54_activ_2 PF14532.6 ETS73983.1 - 0.072 13.2 0.0 0.31 11.1 0.0 2.1 1 0 0 1 1 1 0 Sigma-54 interaction domain RHH_1 PF01402.21 ETS73983.1 - 0.092 12.7 0.6 1.7 8.7 0.3 2.7 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family AAA_29 PF13555.6 ETS73983.1 - 0.14 11.9 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.14 ETS73983.1 - 0.14 11.4 1.1 0.61 9.3 0.1 2.2 2 0 0 2 2 2 0 KAP family P-loop domain YabA PF06156.13 ETS73983.1 - 0.23 12.1 3.1 5.5 7.7 0.0 2.8 2 0 0 2 2 2 0 Initiation control protein YabA DUF4974 PF16344.5 ETS73984.1 - 0.002 18.1 0.5 56 3.8 0.0 4.6 3 2 2 5 5 5 0 Domain of unknown function (DUF4974) PMI_typeI PF01238.21 ETS73984.1 - 0.0023 17.2 3.7 0.026 13.7 0.8 2.7 1 1 2 3 3 3 1 Phosphomannose isomerase type I GET2 PF08690.10 ETS73984.1 - 0.028 14.1 11.8 0.036 13.8 11.8 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 BID PF06393.11 ETS73984.1 - 0.033 13.7 7.0 3.2 7.3 0.1 3.7 1 1 4 5 5 5 0 BH3 interacting domain (BID) Pex19 PF04614.12 ETS73984.1 - 0.064 13.0 16.4 0.22 11.3 16.0 2.0 1 1 1 2 2 2 0 Pex19 protein family ZYG-11_interact PF05884.12 ETS73984.1 - 0.2 11.0 2.8 2.8 7.3 1.1 2.8 1 1 2 3 3 3 0 Interactor of ZYG-11 DUF3632 PF12311.8 ETS73984.1 - 0.59 10.6 7.9 1.4 9.3 4.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3632) DUF1018 PF06252.12 ETS73984.1 - 1 10.4 10.1 3.1 8.8 1.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1018) SPO11_like PF03533.14 ETS73984.1 - 1.5 9.0 18.3 10 6.3 0.7 4.2 4 0 0 4 4 4 0 SPO11 homologue DUF4404 PF14357.6 ETS73984.1 - 2.3 8.9 10.9 9.9 6.9 2.0 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) YebO PF13974.6 ETS73984.1 - 4.9 7.3 10.5 21 5.3 0.3 3.6 1 1 3 4 4 4 0 YebO-like protein U1snRNP70_N PF12220.8 ETS73984.1 - 4.9 7.9 5.8 40 4.9 0.2 2.8 1 1 2 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF1631 PF07793.11 ETS73984.1 - 5.1 5.4 17.6 6.9 5.0 17.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF2203 PF09969.9 ETS73986.1 - 0.0051 17.5 0.8 0.55 11.0 0.7 3.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2203) Com_YlbF PF06133.11 ETS73986.1 - 0.11 13.1 5.1 2.1 9.0 0.5 3.0 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA DUF1664 PF07889.12 ETS73986.1 - 0.54 10.3 2.6 0.98 9.5 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Yippee-Mis18 PF03226.14 ETS73987.1 - 1.8e-12 47.4 0.5 4.1e-12 46.2 0.2 1.7 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SNAD2 PF18745.1 ETS73987.1 - 0.067 12.9 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 AAA PF00004.29 ETS73988.1 - 1.6e-14 54.4 0.0 5e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS73988.1 - 0.0013 19.0 0.4 0.007 16.6 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS73988.1 - 0.0015 19.0 0.0 0.0059 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 ETS73988.1 - 0.018 15.4 0.0 0.054 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ETS73988.1 - 0.022 14.8 0.0 0.051 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 ETS73988.1 - 0.026 14.3 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ETS73988.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 ETS73988.1 - 0.11 12.7 0.0 0.4 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ETS73988.1 - 0.24 10.7 0.5 0.69 9.2 0.2 1.9 2 0 0 2 2 2 0 KaiC OAD_gamma PF04277.13 ETS73989.1 - 5.2 7.7 6.9 27 5.5 0.6 2.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain NPP1 PF05630.11 ETS73990.1 - 5.4e-56 189.8 1.7 6.3e-56 189.6 1.7 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Vps62 PF06101.11 ETS73990.1 - 0.016 13.5 1.0 0.022 13.1 1.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 62 p450 PF00067.22 ETS73991.1 - 1.9e-69 234.6 0.0 2.4e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EthD PF07110.11 ETS73992.1 - 6.8e-15 56.0 0.1 8e-15 55.8 0.1 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 ETS73992.1 - 0.036 14.5 0.0 0.067 13.6 0.0 1.6 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase Glyco_hydro_3_C PF01915.22 ETS73995.1 - 4.5e-41 141.1 0.0 8.1e-41 140.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS73995.1 - 1.9e-37 129.3 0.0 3.3e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS73995.1 - 1.5e-20 73.0 0.2 2.9e-20 72.1 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Beta-lactamase PF00144.24 ETS73996.1 - 5.8e-28 98.1 0.0 8.7e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_M24 PF00557.24 ETS73998.1 - 4.3e-09 36.4 0.0 7.2e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 ETS73998.1 - 3.1e-06 27.9 0.0 8.8e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Creatinase/Prolidase N-terminal domain OCD_Mu_crystall PF02423.15 ETS73999.1 - 1.6e-16 60.2 0.0 2e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 ETS73999.1 - 8e-06 26.0 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OST3_OST6 PF04756.13 ETS73999.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Arginosuc_synth PF00764.19 ETS74000.1 - 1.4e-38 133.2 0.0 1.6e-38 133.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 ETS74000.1 - 0.0053 16.3 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 ETS74000.1 - 0.024 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase tRNA_Me_trans PF03054.16 ETS74000.1 - 0.042 12.6 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase APH PF01636.23 ETS74001.1 - 2.5e-17 63.6 0.3 4.1e-17 62.9 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ETS74001.1 - 0.00042 19.7 0.1 0.0009 18.6 0.1 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 ETS74001.1 - 0.013 14.4 0.1 0.026 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 ETS74001.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase FlhD PF05247.13 ETS74001.1 - 0.21 11.9 0.5 0.51 10.6 0.1 1.8 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhD) DUF1479 PF07350.12 ETS74002.1 - 7.8e-153 509.1 0.0 9.2e-153 508.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 ETS74002.1 - 0.0023 18.2 0.2 0.43 10.8 0.1 2.7 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans PF04082.18 ETS74003.1 - 0.00018 20.6 0.1 0.00036 19.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HBS1_N PF08938.10 ETS74004.1 - 0.095 13.0 0.1 1.1 9.6 0.0 2.4 2 1 1 3 3 3 0 HBS1 N-terminus Pkinase_fungal PF17667.1 ETS74005.1 - 3.5e-50 171.0 0.1 3.9e-50 170.8 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 ETS74005.1 - 8.6e-06 25.3 0.0 1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 ETS74005.1 - 0.017 15.0 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 ETS74005.1 - 0.02 14.2 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.14 ETS74005.1 - 0.18 11.1 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 ETS74006.1 - 2.4e-21 76.3 0.0 4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS74006.1 - 4.1e-13 49.2 0.0 6.5e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase VWA PF00092.28 ETS74006.1 - 0.0035 17.6 0.6 0.04 14.2 0.0 2.4 2 1 0 2 2 2 1 von Willebrand factor type A domain CCSMST1 PF15013.6 ETS74007.1 - 0.07 13.3 3.1 0.6 10.3 1.8 2.6 2 0 0 2 2 2 0 CCSMST1 family YebO PF13974.6 ETS74007.1 - 1.8 8.7 4.7 0.85 9.7 1.1 2.3 2 0 0 2 2 2 0 YebO-like protein EHN PF06441.12 ETS74009.1 - 1.9e-29 102.2 0.1 3.2e-29 101.5 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ETS74009.1 - 2.7e-10 40.3 0.1 4.5e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS74009.1 - 6.8e-05 23.6 8.8 6.8e-05 23.6 8.8 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Glyco_hydro_11 PF00457.17 ETS74011.1 - 2.8e-62 209.5 11.3 3.2e-62 209.3 11.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF3724 PF12521.8 ETS74011.1 - 0.033 14.1 2.8 0.22 11.5 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3724) ABC_tran PF00005.27 ETS74012.1 - 8.6e-41 139.7 0.0 3.9e-21 76.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS74012.1 - 2.8e-32 112.5 44.1 2.9e-26 92.7 20.3 3.2 4 0 0 4 4 4 2 ABC transporter transmembrane region AAA_21 PF13304.6 ETS74012.1 - 6e-08 32.9 1.6 0.022 14.6 0.0 3.3 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETS74012.1 - 6.1e-08 32.4 0.2 0.088 12.2 0.4 3.6 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ETS74012.1 - 0.018 15.1 0.2 0.51 10.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ETS74012.1 - 0.02 14.7 0.4 0.17 11.7 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ETS74012.1 - 0.031 14.8 0.1 0.077 13.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ETS74012.1 - 0.053 13.7 0.6 0.19 11.9 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 ETS74012.1 - 0.071 13.4 0.0 0.37 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ETS74012.1 - 0.076 12.9 0.3 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_15 PF13175.6 ETS74012.1 - 0.14 11.9 1.2 0.21 11.3 0.4 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 ETS74012.1 - 0.16 12.4 0.1 2.9 8.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Fic PF02661.18 ETS74014.1 - 1.1e-12 48.6 0.0 2.5e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family Epimerase PF01370.21 ETS74015.1 - 0.00035 20.1 0.0 0.00053 19.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Kelch_4 PF13418.6 ETS74016.1 - 9e-32 108.8 11.0 2.1e-05 24.4 1.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 ETS74016.1 - 1.7e-30 104.5 5.4 3.1e-07 30.2 0.1 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 ETS74016.1 - 1.2e-27 95.3 7.6 4.9e-11 42.5 0.5 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 ETS74016.1 - 3.6e-25 87.3 4.2 3.6e-08 32.9 0.1 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 ETS74016.1 - 9.7e-25 86.3 6.9 1.8e-05 24.9 0.1 6.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 ETS74016.1 - 2.7e-21 74.7 9.5 1.3e-06 28.2 0.1 6.7 6 1 0 6 6 6 4 Kelch motif RAG2 PF03089.14 ETS74016.1 - 0.12 11.3 0.1 5.8 5.8 0.0 3.2 5 0 0 5 5 5 0 Recombination activating protein 2 Vac_Fusion PF02346.16 ETS74016.1 - 0.54 9.9 2.7 5.3 6.7 0.1 3.7 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Raptor_N PF14538.6 ETS74017.1 - 5.3e-65 217.9 0.0 1.1e-64 216.8 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 ETS74017.1 - 5.5e-06 27.0 5.6 1.5 9.9 0.0 6.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS74017.1 - 0.00018 21.8 0.2 9.6 6.6 0.0 4.7 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 PF13646.6 ETS74017.1 - 0.0006 20.1 1.5 0.003 17.9 0.1 2.6 3 0 0 3 3 3 1 HEAT repeats BBS2_Mid PF14783.6 ETS74017.1 - 0.0093 16.0 0.1 0.55 10.3 0.1 2.7 1 1 1 2 2 2 1 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.22 ETS74017.1 - 3.6 8.1 9.3 41 4.8 0.3 4.9 6 0 0 6 6 6 0 HEAT repeat HRXXH PF13933.6 ETS74018.1 - 3.3e-100 334.7 0.0 4.7e-100 334.2 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 ETS74018.1 - 9.9e-06 26.2 1.0 2.1e-05 25.1 0.0 2.0 2 1 0 2 2 2 1 Lysine-specific metallo-endopeptidase VWA_N2 PF16164.5 ETS74019.1 - 1.8 8.8 10.6 0.75 10.0 2.1 2.3 2 0 0 2 2 2 0 VWA N-terminal SSP160 PF06933.11 ETS74019.1 - 5 5.2 21.9 0.99 7.5 8.4 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Zip PF02535.22 ETS74020.1 - 7.1e-33 114.2 43.9 2.5e-13 49.9 7.3 3.7 3 1 1 4 4 4 3 ZIP Zinc transporter BH4 PF02180.17 ETS74020.1 - 0.23 11.3 0.1 0.42 10.5 0.1 1.4 1 0 0 1 1 1 0 Bcl-2 homology region 4 VWA_N2 PF16164.5 ETS74020.1 - 1.6 8.9 6.5 3.1 8.0 0.0 2.7 2 1 1 3 3 3 0 VWA N-terminal OTT_1508_deam PF14441.6 ETS74021.1 - 1.9e-17 63.0 0.1 5.1e-17 61.6 0.1 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase SAM_KSR1 PF13543.6 ETS74021.1 - 0.038 14.1 0.1 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Dynamin_N PF00350.23 ETS74022.1 - 1.9e-31 109.4 0.0 4.3e-31 108.2 0.0 1.6 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 ETS74022.1 - 1.5e-24 86.7 0.0 3.3e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 ETS74022.1 - 3.7e-05 23.8 0.0 0.00039 20.5 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 ETS74022.1 - 0.019 15.5 0.3 5.2 7.6 0.0 3.0 3 0 0 3 3 3 0 ABC transporter AAA_15 PF13175.6 ETS74022.1 - 0.031 14.0 0.3 0.48 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 ETS74022.1 - 0.041 13.7 0.0 0.32 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ALMT PF11744.8 ETS74022.1 - 0.1 11.4 0.4 0.16 10.8 0.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter p450 PF00067.22 ETS74023.1 - 8.7e-39 133.5 0.0 1e-38 133.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GFA PF04828.14 ETS74025.1 - 7.4e-21 74.3 2.7 1.6e-08 34.8 0.0 3.4 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DUF446 PF04287.12 ETS74027.1 - 0.053 13.6 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 tRNA pseudouridine synthase C adh_short_C2 PF13561.6 ETS74028.1 - 1.7e-34 119.4 0.1 1.4e-32 113.2 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS74028.1 - 1.6e-33 115.8 0.0 2.3e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS74028.1 - 4.4e-08 33.3 0.1 8.5e-08 32.3 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS74028.1 - 0.018 14.5 0.0 0.8 9.1 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS74028.1 - 0.12 11.7 0.0 6.8 6.0 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Ank_2 PF12796.7 ETS74029.1 - 1e-59 199.0 9.1 4.3e-17 62.5 1.1 5.4 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS74029.1 - 1.9e-42 138.3 3.8 0.0019 18.5 0.0 10.9 11 0 0 11 11 11 10 Ankyrin repeat Ank PF00023.30 ETS74029.1 - 2e-39 132.3 15.8 0.00023 21.5 0.0 10.4 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.6 ETS74029.1 - 8.9e-38 128.2 13.7 3.6e-08 33.8 0.1 7.2 3 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS74029.1 - 8.4e-23 80.1 13.3 0.0099 16.2 0.0 9.7 1 1 9 10 10 10 7 Ankyrin repeats (many copies) DUF4350 PF14258.6 ETS74029.1 - 0.00025 21.4 1.3 23 5.5 0.0 6.0 7 0 0 7 7 7 0 Domain of unknown function (DUF4350) Mur_ligase PF01225.25 ETS74029.1 - 0.003 17.9 2.3 1.6 9.1 0.2 4.0 1 1 3 4 4 4 1 Mur ligase family, catalytic domain VWA_3_C PF18571.1 ETS74029.1 - 0.65 9.9 3.5 81 3.2 0.0 4.8 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain HET PF06985.11 ETS74030.1 - 3.5e-36 124.7 0.4 5e-36 124.2 0.4 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 ETS74031.1 - 1.3e-21 76.9 36.7 5.5e-13 48.6 8.1 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS74031.1 - 0.0046 15.9 14.7 0.17 10.7 7.5 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter HET PF06985.11 ETS74032.1 - 3.2e-25 89.2 0.4 6.1e-25 88.3 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) zf-RanBP PF00641.18 ETS74032.1 - 6.7 6.1 5.8 2.9 7.3 0.9 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Ank_4 PF13637.6 ETS74033.1 - 9.2e-71 233.4 17.8 6.9e-16 58.4 0.1 8.2 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS74033.1 - 6.7e-60 199.7 13.3 4.6e-17 62.4 0.0 6.2 3 1 4 7 7 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 ETS74033.1 - 5.1e-46 153.2 17.1 1.2e-06 28.7 0.1 10.5 9 1 1 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 ETS74033.1 - 8.5e-46 153.4 9.1 2.3e-10 40.5 0.0 7.8 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS74033.1 - 4.9e-45 146.3 15.4 1.7e-06 27.9 0.0 12.5 13 1 0 13 13 12 6 Ankyrin repeat NACHT PF05729.12 ETS74033.1 - 5.6e-09 36.1 0.2 2.1e-08 34.3 0.1 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 ETS74033.1 - 3.6e-06 27.5 1.6 3.9e-05 24.1 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ETS74033.1 - 0.00015 22.0 0.0 0.00076 19.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 ETS74033.1 - 0.00021 20.7 0.2 0.024 13.9 0.0 2.3 2 0 0 2 2 2 1 KAP family P-loop domain ABC_tran PF00005.27 ETS74033.1 - 0.01 16.4 0.0 0.044 14.3 0.0 2.0 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 ETS74033.1 - 0.017 15.5 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 ETS74033.1 - 0.051 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.7 ETS74033.1 - 0.091 11.7 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.23 ETS74033.1 - 0.13 12.3 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 ETS74033.1 - 0.13 12.8 0.0 0.44 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 ETS74033.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_30 PF13604.6 ETS74033.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 ETS74034.1 - 2.5e-06 26.5 0.0 2.9e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 ETS74035.1 - 1.8e-30 106.2 0.3 3e-30 105.5 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.29 ETS74037.1 - 5.1e-17 62.5 0.0 1.2e-16 61.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS74037.1 - 0.0079 16.6 0.0 0.025 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS74037.1 - 0.018 15.3 3.3 0.046 14.0 0.1 2.8 2 1 1 3 3 3 0 AAA domain AAA_5 PF07728.14 ETS74037.1 - 0.026 14.5 0.2 0.18 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 ETS74037.1 - 0.055 13.8 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ETS74037.1 - 0.078 13.2 0.0 0.27 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ETS74037.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ETS74037.1 - 0.092 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 ETS74037.1 - 0.14 12.1 0.1 20 5.0 0.0 2.7 2 0 0 2 2 2 0 NTPase PNP_UDP_1 PF01048.20 ETS74038.1 - 4.7e-17 62.0 0.0 1.9e-16 60.0 0.0 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily Arylsulfotran_2 PF14269.6 ETS74039.1 - 4e-47 161.0 0.1 5.7e-47 160.5 0.1 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 ETS74039.1 - 5.2e-10 38.8 0.0 1.2e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Fungal_trans_2 PF11951.8 ETS74040.1 - 0.00028 19.8 0.1 0.00075 18.4 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Metallophos PF00149.28 ETS74041.1 - 3.5e-11 44.0 0.0 1.1e-10 42.4 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ETS74041.1 - 5.4e-07 29.9 0.4 7.4e-06 26.3 0.0 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DUF4131 PF13567.6 ETS74041.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Pet191_N PF10203.9 ETS74042.1 - 5.9e-16 58.5 0.4 8.3e-16 58.1 0.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Abhydrolase_1 PF00561.20 ETS74043.1 - 5.2e-24 85.3 0.2 3.3e-23 82.6 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 ETS74043.1 - 1e-22 79.5 0.1 2.1e-22 78.5 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region FSH1 PF03959.13 ETS74043.1 - 0.0047 16.6 0.1 2.8 7.5 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 ETS74043.1 - 0.0048 16.2 0.0 3.2 6.9 0.0 2.5 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Herpes_DNAp_acc PF04929.12 ETS74043.1 - 4.5 6.1 9.9 6.9 5.5 9.9 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TAL_FSA PF00923.19 ETS74044.1 - 8.1e-95 317.5 1.5 9.3e-95 317.3 1.5 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase C5-epim_C PF06662.13 ETS74044.1 - 0.083 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus SNase PF00565.17 ETS74045.1 - 2.7e-68 227.3 5.7 5.1e-21 75.2 0.3 5.7 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.24 ETS74045.1 - 2e-26 92.4 0.0 9.7e-26 90.2 0.0 2.2 2 0 0 2 2 2 1 Tudor domain SMN PF06003.12 ETS74045.1 - 9.8e-06 25.0 0.2 9.8e-06 25.0 0.2 1.8 2 1 0 2 2 2 1 Survival motor neuron protein (SMN) Peptidase_S31 PF05578.12 ETS74045.1 - 0.062 12.8 0.3 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Pestivirus NS3 polyprotein peptidase S31 Sod_Cu PF00080.20 ETS74046.1 - 7e-46 155.9 5.6 8.1e-46 155.7 5.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CNH PF00780.22 ETS74047.1 - 8.6e-62 209.2 0.0 1.3e-61 208.7 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ETS74047.1 - 1.9e-31 109.7 1.7 3.3e-31 108.9 1.7 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 ETS74047.1 - 1.1e-10 41.7 0.0 3.4e-09 36.9 0.0 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ETS74047.1 - 0.00043 20.7 0.0 0.01 16.3 0.0 2.6 2 0 0 2 2 2 1 PH domain PH_16 PF17838.1 ETS74047.1 - 0.0041 16.9 0.2 2.1 8.2 0.0 2.5 2 0 0 2 2 2 2 PH domain Het-C PF07217.11 ETS74048.1 - 2.4e-158 528.1 0.0 3.2e-158 527.8 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Zn_dep_PLPC PF00882.18 ETS74048.1 - 0.0042 17.1 0.0 0.0088 16.1 0.0 1.4 1 0 0 1 1 1 1 Zinc dependent phospholipase C SMBP PF16785.5 ETS74048.1 - 1.4 9.1 4.1 3.1 8.1 1.8 2.3 2 0 0 2 2 2 0 Small metal-binding protein IATP PF04568.12 ETS74049.1 - 2.9 8.4 6.6 4.7 7.7 6.6 1.3 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP AF-4 PF05110.13 ETS74049.1 - 3.4 5.6 7.4 4.1 5.4 7.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein FAM199X PF15814.5 ETS74049.1 - 4.7 6.2 9.6 6.9 5.6 9.6 1.3 1 0 0 1 1 1 0 Protein family FAM199X Asparaginase_2 PF01112.18 ETS74050.1 - 5.7e-70 235.8 10.9 7.6e-70 235.3 10.9 1.1 1 0 0 1 1 1 1 Asparaginase CFEM PF05730.11 ETS74051.1 - 9.2e-06 25.7 8.4 2.1e-05 24.5 1.7 3.2 2 0 0 2 2 2 2 CFEM domain bVLRF1 PF18826.1 ETS74052.1 - 5.4e-63 211.3 0.1 9.7e-63 210.5 0.1 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 ETS74052.1 - 0.0003 21.0 0.0 0.00077 19.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF3275 PF11679.8 ETS74052.1 - 0.0062 16.5 0.4 0.0062 16.5 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3275) ORC6 PF05460.13 ETS74052.1 - 0.051 12.8 0.1 0.051 12.8 0.1 2.7 3 0 0 3 3 3 0 Origin recognition complex subunit 6 (ORC6) E1-E2_ATPase PF00122.20 ETS74054.1 - 2.8e-39 134.5 0.9 2.8e-39 134.5 0.9 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ETS74054.1 - 2.7e-38 131.5 5.4 2.7e-38 131.5 5.4 3.1 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ETS74054.1 - 1.5e-21 77.7 1.4 3.4e-10 40.6 0.6 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ETS74054.1 - 3.9e-15 55.7 0.0 7.5e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ETS74054.1 - 1.1e-09 37.8 0.0 3e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ETS74054.1 - 5.1e-05 23.1 0.6 0.00012 21.9 0.6 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.9 ETS74054.1 - 1.2 7.9 10.1 3.7 6.2 2.6 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF2231 PF09990.9 ETS74054.1 - 1.9 9.0 5.8 0.42 11.1 1.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) LEP503 PF15221.6 ETS74054.1 - 4.5 7.7 4.8 6 7.3 0.4 3.2 4 0 0 4 4 4 0 Lens epithelial cell protein LEP503 DUF1218 PF06749.12 ETS74054.1 - 5.8 7.5 12.9 1.6 9.3 3.5 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1218) LPMO_10 PF03067.15 ETS74055.1 - 1.9e-07 32.0 0.0 3e-07 31.3 0.0 1.3 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Peptidase_S41 PF03572.18 ETS74056.1 - 4.8e-09 36.0 0.0 2.6e-08 33.6 0.0 2.0 1 1 0 1 1 1 1 Peptidase family S41 CutC PF03932.14 ETS74056.1 - 0.082 12.4 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 CutC family LEA_3 PF03242.13 ETS74057.1 - 3.4 8.4 8.7 45 4.9 0.2 3.7 1 1 3 4 4 4 0 Late embryogenesis abundant protein DUF3328 PF11807.8 ETS74058.1 - 8.6e-30 104.1 2.8 5.5e-29 101.5 2.8 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) ABC_tran PF00005.27 ETS74059.1 - 4.8e-51 172.9 0.1 3.1e-27 95.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS74059.1 - 8.5e-27 94.5 27.9 5.3e-21 75.5 14.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ETS74059.1 - 4.5e-12 45.9 3.8 2e-05 24.2 0.7 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETS74059.1 - 8.1e-12 45.6 6.3 3.7e-05 23.7 0.0 4.4 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ETS74059.1 - 1.6e-05 25.2 0.0 0.45 10.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 ETS74059.1 - 6.4e-05 23.4 0.5 0.23 11.8 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain T2SSE PF00437.20 ETS74059.1 - 8.5e-05 21.7 0.3 0.018 14.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 ETS74059.1 - 0.00014 21.5 2.3 0.23 11.2 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 ETS74059.1 - 0.00023 21.7 0.1 0.35 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 ETS74059.1 - 0.00024 20.7 0.6 0.039 13.5 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 ETS74059.1 - 0.00051 19.3 0.4 0.063 12.5 0.1 2.6 2 1 0 2 2 2 1 NB-ARC domain RsgA_GTPase PF03193.16 ETS74059.1 - 0.00066 19.6 1.0 0.61 10.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 ETS74059.1 - 0.0011 18.8 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 ETS74059.1 - 0.0013 18.8 0.5 0.44 10.6 0.2 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 ETS74059.1 - 0.0016 18.9 0.5 0.64 10.5 0.0 3.8 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 ETS74059.1 - 0.0021 18.0 1.5 1.4 8.8 0.1 2.6 2 0 0 2 2 2 2 NTPase Zeta_toxin PF06414.12 ETS74059.1 - 0.0085 15.4 0.1 1.4 8.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin ATPase_2 PF01637.18 ETS74059.1 - 0.0086 16.0 0.0 0.7 9.8 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_23 PF13476.6 ETS74059.1 - 0.017 15.6 3.6 2.2 8.7 0.3 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 ETS74059.1 - 0.025 14.6 0.1 0.68 10.0 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 ETS74059.1 - 0.026 14.0 0.4 3.6 7.0 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 ETS74059.1 - 0.033 13.7 0.1 8.4 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 ETS74059.1 - 0.033 14.2 0.5 3.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.6 ETS74059.1 - 0.062 13.5 0.2 2.6 8.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 ETS74059.1 - 0.069 13.4 0.1 31 4.8 0.1 3.5 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 ETS74059.1 - 0.076 12.9 0.2 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 ETS74059.1 - 0.12 12.1 0.1 12 5.5 0.0 3.0 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 ETS74059.1 - 0.13 11.6 0.6 6.4 6.1 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family dNK PF01712.19 ETS74059.1 - 0.13 12.1 0.6 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_19 PF13245.6 ETS74059.1 - 0.17 12.2 0.0 7.3 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 ETS74059.1 - 0.18 11.3 0.0 14 5.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF87 PF01935.17 ETS74059.1 - 0.44 10.6 3.0 0.37 10.8 0.2 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain Pkinase PF00069.25 ETS74060.1 - 1.8e-70 237.4 0.0 1.4e-69 234.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 ETS74060.1 - 3.4e-43 146.1 0.1 7.3e-43 145.0 0.1 1.6 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 ETS74060.1 - 2.8e-36 125.1 0.1 1.1e-32 113.4 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 ETS74060.1 - 1.2e-06 28.0 0.0 2.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ETS74060.1 - 5.9e-06 25.5 0.0 2.2e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 ETS74060.1 - 0.015 15.2 0.0 0.051 13.5 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETS74060.1 - 0.028 14.0 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 ETS74060.1 - 0.028 13.8 0.0 0.079 12.3 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SMC_N PF02463.19 ETS74061.1 - 1.2e-22 80.4 0.0 2.6e-22 79.4 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ETS74061.1 - 4.6e-18 66.5 0.7 4.6e-18 66.5 0.7 5.2 3 2 1 4 4 1 1 AAA domain AAA_15 PF13175.6 ETS74061.1 - 2.2e-11 44.1 0.2 6.7e-06 26.1 0.0 3.1 2 2 1 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 ETS74061.1 - 4.2e-07 30.1 7.1 0.0011 18.9 0.1 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ETS74061.1 - 0.00019 21.1 0.0 0.0004 20.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SRP54 PF00448.22 ETS74061.1 - 0.014 15.0 2.1 0.4 10.3 0.5 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Cauli_AT PF03233.13 ETS74061.1 - 0.018 15.0 0.5 0.018 15.0 0.5 5.3 4 1 0 4 4 4 0 Aphid transmission protein DUF465 PF04325.13 ETS74061.1 - 0.02 14.9 1.7 0.02 14.9 1.7 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF465) AAA_7 PF12775.7 ETS74061.1 - 0.023 14.2 0.0 0.39 10.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 ETS74061.1 - 0.036 14.5 0.1 0.35 11.3 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS74061.1 - 0.077 13.3 2.0 4.4 7.6 0.0 3.3 2 0 0 2 2 2 0 AAA domain DUF4548 PF15081.6 ETS74061.1 - 0.18 11.7 3.1 8.8 6.1 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4548) Baculo_PEP_C PF04513.12 ETS74061.1 - 0.26 11.3 13.7 8.6 6.4 1.0 4.6 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_27 PF13514.6 ETS74061.1 - 0.36 10.4 0.0 0.36 10.4 0.0 4.4 6 1 0 6 6 6 0 AAA domain RsgA_GTPase PF03193.16 ETS74061.1 - 0.88 9.5 3.2 2.1 8.3 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase AAA_28 PF13521.6 ETS74061.1 - 2.3 8.5 8.1 1.3 9.2 0.6 3.7 2 1 1 3 3 3 0 AAA domain zf-CCHC PF00098.23 ETS74062.1 - 1.3e-06 28.2 2.7 2.9e-06 27.1 2.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 ETS74062.1 - 0.11 12.3 1.1 0.21 11.4 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 ETS74062.1 - 0.22 11.2 2.6 0.49 10.1 2.6 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Glyco_hydro_43 PF04616.14 ETS74063.1 - 6.4e-62 209.5 0.4 7.6e-62 209.2 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ETS74063.1 - 2.8e-08 33.7 0.0 6.4e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain ESSS PF10183.9 ETS74063.1 - 0.049 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Vps62 PF06101.11 ETS74064.1 - 2.5e-08 32.7 0.0 2.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Protocadherin PF08374.11 ETS74064.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Protocadherin HET PF06985.11 ETS74065.1 - 9.9e-22 77.9 0.2 2.1e-21 76.8 0.2 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Patatin PF01734.22 ETS74066.1 - 1.2e-21 77.8 0.7 4.6e-21 75.9 0.2 2.2 2 1 0 2 2 2 1 Patatin-like phospholipase Ras PF00071.22 ETS74067.1 - 9e-41 139.2 0.1 1.5e-40 138.4 0.1 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS74067.1 - 2.5e-12 47.1 0.0 5.6e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS74067.1 - 0.00023 20.6 0.0 0.00045 19.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family zf-Di19 PF05605.12 ETS74067.1 - 0.0034 17.6 4.8 0.84 10.0 0.6 3.5 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding RNF220 PF15926.5 ETS74067.1 - 0.015 15.0 1.6 0.022 14.4 0.0 2.0 2 1 1 3 3 3 0 E3 ubiquitin-protein ligase RNF220 DUF629 PF04780.12 ETS74067.1 - 0.037 12.6 4.0 0.062 11.8 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF629) MMR_HSR1 PF01926.23 ETS74067.1 - 0.038 14.1 0.0 0.081 13.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase OrsD PF12013.8 ETS74067.1 - 0.075 13.5 4.4 0.99 9.9 0.4 3.0 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-BED PF02892.15 ETS74067.1 - 0.08 13.0 4.0 6.5 6.9 1.1 2.7 2 0 0 2 2 2 0 BED zinc finger SRPRB PF09439.10 ETS74067.1 - 0.093 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-C2H2_4 PF13894.6 ETS74067.1 - 0.26 12.2 13.3 0.82 10.7 0.4 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ETS74067.1 - 0.42 11.0 5.3 8.7 6.7 1.2 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DZR PF12773.7 ETS74067.1 - 0.62 10.1 7.1 29 4.8 7.1 2.6 1 1 0 1 1 1 0 Double zinc ribbon Vps39_2 PF10367.9 ETS74067.1 - 0.77 10.2 2.7 22 5.5 0.1 3.2 2 1 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-C2H2_9 PF16293.5 ETS74067.1 - 1.9 8.4 4.5 4.1 7.3 0.1 3.0 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Sugar_tr PF00083.24 ETS74068.1 - 1.9e-71 241.3 27.6 2.2e-71 241.1 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS74068.1 - 3.4e-23 82.2 44.2 3.5e-16 59.1 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.24 ETS74069.1 - 1.5e-34 120.2 0.3 1.8e-34 119.9 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS74069.1 - 1e-07 32.1 0.1 8.6e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS74069.1 - 1.1e-05 24.8 0.0 0.00065 18.9 0.0 2.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS74069.1 - 0.00039 19.7 0.0 0.033 13.4 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS74069.1 - 0.0031 16.8 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ETS74069.1 - 0.0037 16.6 0.0 0.0073 15.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ETS74069.1 - 0.0072 15.2 0.0 0.25 10.1 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 ETS74069.1 - 0.013 15.5 0.0 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 ETS74069.1 - 0.021 13.9 0.0 4.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.18 ETS74069.1 - 0.026 14.8 0.0 0.33 11.2 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.14 ETS74069.1 - 0.076 11.7 0.0 1.9 7.1 0.0 2.5 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox PF00070.27 ETS74069.1 - 0.087 13.4 0.0 0.44 11.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ETS74069.1 - 0.089 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 ETS74069.1 - 0.097 12.1 0.0 0.37 10.2 0.0 1.9 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus DUF1338 PF07063.13 ETS74070.1 - 4.6e-109 364.5 0.0 5.4e-109 364.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) 2-Hacid_dh_C PF02826.19 ETS74071.1 - 1.6e-58 197.0 0.0 2.3e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS74071.1 - 1.2e-19 70.3 0.0 1.5e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ETS74071.1 - 9.3e-09 35.6 0.2 3.3e-08 33.8 0.1 2.0 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ETS74071.1 - 0.00062 20.3 0.0 0.0012 19.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 ETS74071.1 - 0.024 14.2 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 ETS74071.1 - 0.038 13.6 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Asp_Glu_race PF01177.22 ETS74072.1 - 9.2e-05 22.4 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Amdase PF17645.1 ETS74072.1 - 0.00014 21.5 0.0 0.51 9.9 0.0 2.2 2 0 0 2 2 2 2 Arylmalonate decarboxylase Aldolase_II PF00596.21 ETS74073.1 - 8e-50 169.4 0.0 1e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fungal_trans PF04082.18 ETS74074.1 - 1.7e-29 102.7 0.0 3.1e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS74074.1 - 0.025 14.7 4.4 0.059 13.5 4.4 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 ETS74075.1 - 2.3e-24 86.4 0.1 3e-24 86.1 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS74075.1 - 2.4e-11 43.1 0.0 1.7e-10 40.3 0.0 2.1 2 1 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 ETS74075.1 - 0.00058 18.9 0.2 0.0058 15.5 0.2 2.0 1 1 0 1 1 1 1 Carboxylesterase family 3D PF06725.11 ETS74075.1 - 0.015 15.5 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 3D domain AAA_16 PF13191.6 ETS74076.1 - 1.1e-10 42.2 0.4 3.6e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain gag-asp_proteas PF13975.6 ETS74076.1 - 1.2e-10 41.7 0.0 1.1e-05 25.9 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 ETS74076.1 - 1.9e-08 34.8 0.3 0.0022 18.6 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease NB-ARC PF00931.22 ETS74076.1 - 1.1e-05 24.8 0.0 2.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 ETS74076.1 - 5.9e-05 23.4 0.7 0.00049 20.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain Asp_protease PF09668.10 ETS74076.1 - 0.00066 19.5 0.0 0.063 13.1 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease ATPase_2 PF01637.18 ETS74076.1 - 0.0025 17.8 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 ETS74076.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 ETS74076.1 - 0.15 12.1 0.2 9.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE LIAS_N PF16881.5 ETS74076.1 - 0.17 12.3 0.4 3.2 8.2 0.0 2.6 2 0 0 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family DUF5418 PF17439.2 ETS74077.1 - 0.11 12.6 2.4 0.18 11.9 2.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5418) PNP_UDP_1 PF01048.20 ETS74078.1 - 2.7e-15 56.2 0.3 1.3e-14 54.1 0.3 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily IL17 PF06083.11 ETS74078.1 - 0.16 12.5 1.5 1.5 9.3 0.5 2.3 2 0 0 2 2 2 0 Interleukin-17 TPR_10 PF13374.6 ETS74079.1 - 5.8e-47 156.4 9.9 1.4e-11 43.9 0.2 7.5 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 ETS74079.1 - 3.6e-43 145.7 19.2 6.3e-13 48.8 0.3 6.6 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 ETS74079.1 - 5.2e-07 29.3 13.6 0.048 13.7 0.3 6.2 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 ETS74079.1 - 1.6e-06 27.7 13.9 0.13 12.1 0.1 5.7 5 1 1 6 6 6 3 Tetratricopeptide repeat AAA_22 PF13401.6 ETS74079.1 - 3.3e-05 24.2 0.0 8.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain TPR_8 PF13181.6 ETS74079.1 - 0.0004 20.4 8.1 0.047 13.9 0.5 4.2 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 ETS74079.1 - 0.0017 18.6 2.2 13 6.4 0.1 4.7 3 1 0 3 3 3 0 Tetratricopeptide repeat NB-ARC PF00931.22 ETS74079.1 - 0.012 14.8 0.0 0.48 9.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain TPR_2 PF07719.17 ETS74079.1 - 0.015 15.3 0.7 0.015 15.3 0.7 5.2 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 ETS74079.1 - 0.023 15.2 6.4 2.5 8.7 0.4 4.6 4 1 2 6 6 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 ETS74079.1 - 0.033 14.5 1.9 0.43 10.9 0.2 3.6 3 2 1 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS74079.1 - 0.061 13.6 1.4 13 6.1 0.0 3.8 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RNA_pol_3_Rpc31 PF11705.8 ETS74079.1 - 0.08 13.2 8.8 0.21 11.8 8.8 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 ETS74079.1 - 0.22 9.7 13.8 0.32 9.1 13.8 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 ETS74079.1 - 0.47 9.7 6.7 0.96 8.7 6.7 1.5 1 0 0 1 1 1 0 BUD22 Astro_capsid_p PF12226.8 ETS74079.1 - 0.79 8.8 7.2 1.4 8.0 7.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TPR_3 PF07720.12 ETS74079.1 - 0.87 9.6 15.8 0.78 9.8 1.6 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.10 ETS74079.1 - 0.92 9.9 15.6 0.074 13.4 9.9 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PPR PF01535.20 ETS74079.1 - 1.1 9.7 3.0 9.4 6.7 0.1 3.8 4 0 0 4 4 3 0 PPR repeat TPR_16 PF13432.6 ETS74079.1 - 1.1 9.9 0.0 1.1 9.9 0.0 4.0 5 0 0 5 5 2 0 Tetratricopeptide repeat Sigma70_ner PF04546.13 ETS74079.1 - 1.3 8.9 10.9 0.59 10.0 6.0 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region TFIIA PF03153.13 ETS74079.1 - 1.8 8.5 9.2 3.5 7.5 9.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mrpl_C PF18502.1 ETS74079.1 - 4.6 7.6 5.4 12 6.2 0.6 3.5 2 1 1 4 4 3 0 54S ribosomal protein L8 C-terminal domain NOA36 PF06524.12 ETS74079.1 - 6.6 6.0 15.7 15 4.8 15.7 1.5 1 0 0 1 1 1 0 NOA36 protein COesterase PF00135.28 ETS74080.1 - 1.1e-81 275.3 0.0 1.5e-81 274.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS74080.1 - 6.7e-09 35.9 0.5 5.9e-08 32.8 0.5 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS74080.1 - 0.0011 18.5 0.1 0.0029 17.1 0.1 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family LigB PF02900.18 ETS74081.1 - 1.1e-32 113.2 0.0 1.3e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase adh_short PF00106.25 ETS74082.1 - 7.1e-07 28.9 0.0 1.4e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS74082.1 - 1.4e-06 28.1 0.0 1.8e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 ETS74082.1 - 0.014 14.5 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 ETS74082.1 - 0.033 13.6 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 ETS74082.1 - 0.08 12.4 0.0 0.17 11.3 0.0 1.5 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 ETS74082.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 ETS74083.1 - 1.1e-50 172.6 0.1 1.4e-50 172.3 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS74083.1 - 5e-08 32.9 7.0 1.1e-07 31.9 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Endonuclease_7 PF02945.15 ETS74083.1 - 0.33 10.9 0.0 0.33 10.9 0.0 2.4 2 0 0 2 2 2 0 Recombination endonuclease VII EthD PF07110.11 ETS74084.1 - 0.051 14.7 0.1 0.7 11.1 0.1 2.1 1 1 0 1 1 1 0 EthD domain Carot_N PF09150.10 ETS74084.1 - 0.07 13.0 0.0 0.076 12.9 0.0 1.1 1 0 0 1 1 1 0 Orange carotenoid protein, N-terminal Glyco_hydro_28 PF00295.17 ETS74085.1 - 5.7e-35 120.9 0.7 8.4e-35 120.4 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 ETS74085.1 - 0.2 11.5 11.5 0.053 13.4 4.9 2.9 1 1 2 3 3 3 0 Right handed beta helix region Pkinase PF00069.25 ETS74086.1 - 1.9e-52 178.3 0.0 2.5e-49 168.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS74086.1 - 1.8e-31 109.4 0.0 3.1e-30 105.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 ETS74086.1 - 0.00035 19.7 0.1 0.00062 18.9 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 ETS74086.1 - 0.0046 15.9 0.0 0.0062 15.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ETS74086.1 - 0.0074 15.6 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like SUR7 PF06687.12 ETS74087.1 - 6.4e-33 114.2 12.1 7.5e-33 114.0 12.1 1.0 1 0 0 1 1 1 1 SUR7/PalI family Holin_BhlA PF10960.8 ETS74087.1 - 0.18 11.8 0.1 0.36 10.8 0.1 1.5 1 0 0 1 1 1 0 BhlA holin family Clc-like PF07062.12 ETS74087.1 - 0.63 9.5 7.3 0.044 13.2 1.8 1.7 2 0 0 2 2 2 0 Clc-like DUF996 PF06195.13 ETS74087.1 - 1.5 9.1 8.8 1.1 9.6 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Zn_clus PF00172.18 ETS74088.1 - 4.6e-08 33.0 4.1 6.5e-08 32.6 4.1 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS74089.1 - 6.6e-19 68.0 0.0 1.5e-18 66.8 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Molybdopterin PF00384.22 ETS74089.1 - 0.077 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin oxidoreductase RE_HpaII PF09561.10 ETS74089.1 - 0.082 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 HpaII restriction endonuclease Dioxygenase_C PF00775.21 ETS74090.1 - 2.2e-09 37.0 0.0 3.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Sporozoite_P67 PF05642.11 ETS74090.1 - 0.32 9.0 4.5 0.37 8.8 4.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ADH_N PF08240.12 ETS74091.1 - 7.5e-10 38.7 0.0 2.6e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS74091.1 - 1.7e-08 34.5 0.1 3.1e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ETS74091.1 - 0.092 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Kinesin PF00225.23 ETS74093.1 - 8.8e-78 261.5 3.5 1e-77 261.3 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ETS74093.1 - 7.3e-36 123.3 0.0 1.8e-35 122.1 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Filament PF00038.21 ETS74093.1 - 0.015 14.9 38.0 0.41 10.2 17.5 3.3 2 1 1 3 3 3 0 Intermediate filament protein Tropomyosin_1 PF12718.7 ETS74093.1 - 0.25 11.5 39.7 0.93 9.6 9.9 3.6 2 1 1 3 3 3 0 Tropomyosin like HOOK PF05622.12 ETS74093.1 - 1.7 6.7 38.5 0.052 11.7 30.2 2.2 2 1 1 3 3 3 0 HOOK protein Pox_A_type_inc PF04508.12 ETS74093.1 - 2 8.4 7.6 6 6.9 1.2 3.8 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF1664 PF07889.12 ETS74093.1 - 2.2 8.3 14.2 4.3 7.4 5.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 ETS74093.1 - 2.4 7.4 21.6 4.9 6.4 13.4 2.3 1 1 1 2 2 2 0 FAM76 protein ATG16 PF08614.11 ETS74093.1 - 4.1 7.6 48.6 1.2 9.3 25.0 4.2 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) CALM_bind PF16025.5 ETS74094.1 - 0.024 15.1 1.2 0.043 14.3 1.2 1.4 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding AhpC-TSA_2 PF13911.6 ETS74095.1 - 6.7e-11 42.3 0.1 1.2e-10 41.5 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 ETS74095.1 - 5.1e-09 36.1 0.0 9.9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ETS74095.1 - 0.00075 19.2 0.0 0.0031 17.3 0.0 1.9 1 1 1 2 2 2 1 Redoxin PAP_assoc PF03828.19 ETS74096.1 - 7.6e-16 58.1 0.1 1.6e-15 57.1 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 ETS74096.1 - 0.00059 20.1 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain GFA PF04828.14 ETS74097.1 - 1.6e-17 63.6 1.3 2.2e-17 63.2 1.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme YmaF PF12788.7 ETS74097.1 - 0.013 16.0 0.1 0.02 15.4 0.1 1.3 1 0 0 1 1 1 0 YmaF family zf-ACC PF17848.1 ETS74097.1 - 0.015 15.4 0.3 0.5 10.5 0.0 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain HET PF06985.11 ETS74098.1 - 5.2e-08 33.4 6.0 3.7e-06 27.4 2.2 2.5 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF4528 PF15031.6 ETS74098.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) OPT PF03169.15 ETS74101.1 - 1.2e-175 585.7 56.5 1.4e-175 585.5 56.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SH3_1 PF00018.28 ETS74102.1 - 9.7e-15 53.9 0.3 1.5e-14 53.3 0.3 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ETS74102.1 - 3.2e-10 39.7 0.1 4.8e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ETS74102.1 - 7.5e-10 38.3 0.0 1.3e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF910 PF06014.11 ETS74102.1 - 0.028 14.4 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) NUDE_C PF04880.13 ETS74102.1 - 5.1 7.6 7.1 9.4 6.7 7.2 1.4 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region EAF PF09816.9 ETS74103.1 - 1e-18 67.5 0.1 2.9e-18 66.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Cwf_Cwc_15 PF04889.12 ETS74103.1 - 1.4 8.6 28.0 3 7.5 9.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein adh_short_C2 PF13561.6 ETS74104.1 - 2e-56 191.2 0.0 2.8e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS74104.1 - 4e-43 147.2 0.3 7.5e-43 146.3 0.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS74104.1 - 2.8e-08 33.9 0.1 4.2e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 KR domain Ala_racemase_N PF01168.20 ETS74105.1 - 5.4e-30 104.7 0.2 6.8e-30 104.3 0.2 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 ETS74105.1 - 1.9e-21 76.5 0.0 4.1e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain RuvX PF03652.15 ETS74105.1 - 0.012 16.0 0.0 0.032 14.6 0.0 1.8 1 0 0 1 1 1 0 Holliday junction resolvase Na_Ca_ex PF01699.24 ETS74106.1 - 1.5e-46 158.1 31.3 1.1e-24 87.1 13.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CD20 PF04103.15 ETS74106.1 - 0.0087 16.2 5.7 0.12 12.4 2.2 3.0 1 1 1 2 2 2 2 CD20-like family GLE1 PF07817.13 ETS74106.1 - 0.026 13.8 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 GLE1-like protein Glyoxalase PF00903.25 ETS74107.1 - 3.2e-40 137.3 0.3 5.5e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ETS74107.1 - 2.1e-16 60.2 0.1 1.6e-06 28.4 0.0 3.7 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ETS74107.1 - 5.2e-08 33.6 0.0 0.0071 17.1 0.0 2.9 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 ETS74107.1 - 7.2e-06 26.2 0.0 0.057 13.5 0.0 3.2 2 1 1 3 3 3 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 ETS74107.1 - 5.3e-05 23.1 0.5 1.1 9.2 0.0 4.1 4 0 0 4 4 4 1 Glyoxalase-like domain CppA_N PF14506.6 ETS74107.1 - 0.014 15.5 0.1 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 CppA N-terminal DUF1338 PF07063.13 ETS74107.1 - 0.038 13.2 0.1 29 3.7 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF1338) MoaF PF10703.9 ETS74107.1 - 0.042 13.8 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 MoaF N-terminal domain NIL PF09383.10 ETS74107.1 - 0.066 13.1 0.0 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 NIL domain Cas_GSU0053 PF09617.10 ETS74107.1 - 0.12 12.3 0.0 0.76 9.7 0.0 2.0 2 0 0 2 2 2 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) Pfk_N PF18468.1 ETS74107.1 - 0.15 12.5 0.1 8.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Phosphofructokinase N-terminal domain yeast 2-Hacid_dh_C PF02826.19 ETS74108.1 - 1.5e-51 174.3 0.0 2.3e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS74108.1 - 9.4e-33 112.7 0.0 1.5e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 ETS74108.1 - 0.057 13.9 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain Epimerase PF01370.21 ETS74109.1 - 2.5e-11 43.5 0.0 5.7e-11 42.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS74109.1 - 1.8e-07 31.2 0.3 2.4e-07 30.8 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding HIM1 PF08732.10 ETS74109.1 - 2.8e-07 30.2 0.0 4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 HIM1 3Beta_HSD PF01073.19 ETS74109.1 - 0.00069 18.7 0.0 0.0027 16.7 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 ETS74109.1 - 0.00087 18.9 0.7 0.003 17.2 0.7 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 ETS74109.1 - 0.001 18.3 0.0 1.5 7.9 0.0 2.5 2 1 1 3 3 3 2 Male sterility protein adh_short_C2 PF13561.6 ETS74109.1 - 0.02 14.5 0.0 0.086 12.4 0.0 1.8 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Semialdhyde_dh PF01118.24 ETS74109.1 - 0.037 14.5 0.0 0.084 13.3 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Cytokin-bind PF09265.10 ETS74109.1 - 0.062 12.7 0.0 0.11 11.8 0.0 1.4 1 1 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding SelR PF01641.18 ETS74110.1 - 1.1e-48 164.3 0.1 1.3e-48 164.0 0.1 1.1 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 ETS74110.1 - 0.0039 16.9 0.1 0.21 11.4 0.0 2.2 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 ETS74110.1 - 0.0074 16.5 0.5 0.02 15.1 0.5 1.7 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TF_Zn_Ribbon PF08271.12 ETS74110.1 - 0.039 13.5 1.8 0.62 9.6 0.2 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding MCM_OB PF17207.3 ETS74110.1 - 0.14 12.0 0.1 0.3 11.0 0.0 1.5 2 0 0 2 2 2 0 MCM OB domain Zn_ribbon_recom PF13408.6 ETS74110.1 - 0.38 11.3 3.2 6.8 7.3 0.2 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DZR PF12773.7 ETS74110.1 - 0.51 10.4 3.6 4.2 7.5 2.7 2.2 1 1 1 2 2 2 0 Double zinc ribbon Isochorismatase PF00857.20 ETS74112.1 - 4.1e-41 141.1 0.0 4.7e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Ferrochelatase PF00762.19 ETS74112.1 - 0.049 12.7 0.2 0.71 8.9 0.1 2.0 2 0 0 2 2 2 0 Ferrochelatase Poty_coat PF00767.18 ETS74112.1 - 0.13 11.8 0.3 0.67 9.5 0.0 1.9 2 0 0 2 2 2 0 Potyvirus coat protein DUF4552 PF15089.6 ETS74112.1 - 0.17 10.9 0.2 0.28 10.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) Aminotran_1_2 PF00155.21 ETS74113.1 - 4.3e-36 124.9 0.0 6.1e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RPN7 PF10602.9 ETS74114.1 - 8.8e-57 191.6 0.6 1.5e-56 190.9 0.6 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 ETS74114.1 - 3.9e-13 49.8 0.0 8.4e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_6 PF13174.6 ETS74114.1 - 0.088 13.5 2.8 0.59 10.9 0.2 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ETS74114.1 - 0.088 13.0 0.4 0.37 11.0 0.4 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 ETS74114.1 - 0.19 12.6 1.8 0.47 11.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 ETS74114.1 - 0.2 11.7 0.9 0.82 9.8 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 ETS74114.1 - 0.27 11.9 1.7 0.48 11.1 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 ETS74114.1 - 0.27 11.5 1.8 0.36 11.2 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Pox_MCEL PF03291.16 ETS74115.1 - 1.7e-66 224.6 0.0 3.5e-44 151.3 0.0 2.6 2 2 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 ETS74115.1 - 1.8e-09 38.1 0.0 0.00055 20.6 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 ETS74115.1 - 5.1e-08 33.6 0.0 0.013 16.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 ETS74115.1 - 1.3e-05 25.1 0.0 2.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS74115.1 - 5.8e-05 23.7 0.0 0.41 11.3 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 ETS74115.1 - 9e-05 22.3 0.0 0.0022 17.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 ETS74115.1 - 0.0014 17.9 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.17 ETS74115.1 - 0.091 12.2 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_9 PF08003.11 ETS74115.1 - 0.12 11.3 0.1 0.28 10.0 0.0 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1698) MFS_1 PF07690.16 ETS74116.1 - 2.3e-15 56.4 48.6 2.3e-15 56.4 48.6 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily zf-C2H2 PF00096.26 ETS74117.1 - 8.3e-11 41.7 11.8 6.1e-05 23.2 0.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS74117.1 - 7.5e-08 32.6 9.4 0.0012 19.5 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ETS74117.1 - 2.3e-07 31.0 11.4 2.1e-06 27.9 1.2 2.8 3 0 0 3 3 3 2 Zinc-finger double domain BolA PF01722.18 ETS74117.1 - 0.00025 21.3 0.9 0.26 11.6 0.2 2.3 1 1 1 2 2 2 2 BolA-like protein zf-C2H2_jaz PF12171.8 ETS74117.1 - 0.00055 20.2 4.2 0.14 12.5 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ETS74117.1 - 0.00061 19.7 5.9 0.21 11.6 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-MYST PF17772.1 ETS74117.1 - 0.04 13.5 3.9 0.24 11.0 0.4 2.5 2 0 0 2 2 2 0 MYST family zinc finger domain zf-met PF12874.7 ETS74117.1 - 0.55 10.7 0.1 0.55 10.7 0.1 2.9 3 0 0 3 3 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 ETS74117.1 - 0.96 9.3 10.6 0.55 10.0 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-AN1 PF01428.16 ETS74117.1 - 2.6 8.3 9.3 4.5 7.5 1.4 2.4 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2HE PF16278.5 ETS74117.1 - 2.7 8.5 9.1 3.1 8.3 1.9 2.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 ETS74117.1 - 3.7 7.6 13.1 1.4 8.9 2.8 3.0 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Malate_synthase PF01274.22 ETS74118.1 - 9.4e-230 763.3 0.0 1.1e-229 763.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 ETS74118.1 - 0.038 13.1 0.0 0.08 12.1 0.0 1.5 1 1 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Lyase_1 PF00206.20 ETS74119.1 - 2.5e-113 378.6 0.1 3.4e-113 378.1 0.1 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 ETS74119.1 - 2.3e-21 75.9 0.0 2.3e-21 75.9 0.0 1.8 2 0 0 2 2 2 1 Fumarase C C-terminus ADH_N PF08240.12 ETS74119.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Peptidase_C2 PF00648.21 ETS74120.1 - 2.3e-15 56.4 0.0 1.2e-14 54.0 0.0 1.9 1 1 0 1 1 1 1 Calpain family cysteine protease Peptidase_C1 PF00112.23 ETS74120.1 - 0.0074 16.4 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 Papain family cysteine protease DUF1223 PF06764.11 ETS74120.1 - 0.062 13.3 0.5 2.9 7.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1223) p450 PF00067.22 ETS74121.1 - 1.2e-08 34.2 0.0 1.3e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS74122.1 - 1.3e-11 44.0 0.0 1.4e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.7 ETS74124.1 - 5.1e-08 33.8 1.7 7.4e-08 33.3 1.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS74124.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pro_racemase PF05544.11 ETS74125.1 - 4.1e-59 200.2 0.0 5.3e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Proline racemase Fungal_trans PF04082.18 ETS74126.1 - 4.3e-13 48.9 0.4 1.1e-12 47.6 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS74126.1 - 1.3e-07 31.6 14.2 2.5e-07 30.7 14.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ETS74127.1 - 6.4e-29 101.0 31.8 6.4e-29 101.0 31.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS74127.1 - 6.3e-05 22.4 4.1 6.3e-05 22.4 4.1 2.5 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DSBA PF01323.20 ETS74128.1 - 1.4e-26 93.5 0.0 1.6e-26 93.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain FMO-like PF00743.19 ETS74129.1 - 9.5e-26 90.3 0.0 1.1e-13 50.4 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ETS74129.1 - 5.1e-12 45.7 0.0 1.6e-10 40.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS74129.1 - 8.9e-06 25.1 0.0 0.00053 19.2 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ETS74129.1 - 1.9e-05 24.1 0.0 0.00011 21.6 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF2530 PF10745.9 ETS74129.1 - 0.078 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) MFS_1 PF07690.16 ETS74130.1 - 1.9e-36 125.8 31.7 3.5e-35 121.6 34.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS74130.1 - 1e-07 31.6 11.1 4.4e-07 29.5 3.6 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 ETS74130.1 - 1.2e-06 27.6 27.9 2e-05 23.7 28.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter 2OG-FeII_Oxy PF03171.20 ETS74131.1 - 5.4e-14 52.5 0.0 1.3e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ETS74131.1 - 3.7e-08 34.1 0.1 3.7e-08 34.1 0.1 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal MR_MLE_C PF13378.6 ETS74132.1 - 9.8e-30 103.8 0.3 1.3e-29 103.4 0.3 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ETS74132.1 - 1.1e-13 51.5 0.0 2.8e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Aldolase_II PF00596.21 ETS74133.1 - 2.5e-23 83.0 0.0 3.3e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Aldolase_II PF00596.21 ETS74134.1 - 1.9e-18 67.1 0.0 2.2e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Aa_trans PF01490.18 ETS74135.1 - 2.5e-35 122.0 34.9 3e-35 121.7 34.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RTX PF02382.15 ETS74135.1 - 0.28 10.8 2.3 0.26 10.9 0.7 1.7 2 0 0 2 2 2 0 N-terminal domain in RTX protein OCD_Mu_crystall PF02423.15 ETS74136.1 - 4.9e-08 32.3 0.0 5.5e-07 28.8 0.0 2.4 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 ETS74136.1 - 8.9e-06 25.8 0.0 3.9e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ETS74136.1 - 0.032 14.5 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 ETS74136.1 - 0.036 14.9 0.0 0.084 13.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold TruB_C PF09142.11 ETS74136.1 - 0.073 12.9 0.1 0.23 11.3 0.1 1.8 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal TMF_DNA_bd PF12329.8 ETS74136.1 - 0.13 12.3 0.2 0.24 11.4 0.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF521 PF04412.13 ETS74137.1 - 1.5e-129 432.2 0.0 2e-129 431.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.16 ETS74137.1 - 2.7e-28 97.6 0.2 5.3e-28 96.6 0.2 1.5 1 0 0 1 1 1 1 Aconitase X swivel domain Fungal_trans PF04082.18 ETS74138.1 - 8.8e-11 41.3 0.0 2.7e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_114 PF03537.13 ETS74139.1 - 1.2e-43 149.1 0.0 1.5e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 FAD_binding_2 PF00890.24 ETS74140.1 - 3e-72 244.0 0.0 3.9e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ETS74140.1 - 2.2e-07 30.6 0.1 1e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 ETS74140.1 - 1.5e-05 24.8 0.1 0.0046 16.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS74140.1 - 0.00023 21.3 0.6 0.00085 19.5 0.6 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ETS74140.1 - 0.00047 19.0 0.0 0.00079 18.2 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 ETS74140.1 - 0.00049 19.3 1.9 0.016 14.3 0.3 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 ETS74140.1 - 0.0018 17.6 0.0 0.0074 15.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS74140.1 - 0.083 12.1 0.6 0.14 11.4 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 ETS74140.1 - 0.085 12.1 6.3 0.031 13.5 2.0 2.3 3 0 0 3 3 3 0 Thi4 family Pyr_redox PF00070.27 ETS74140.1 - 0.15 12.6 0.3 0.48 11.0 0.3 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS74140.1 - 0.17 11.1 0.2 0.49 9.6 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ERG2_Sigma1R PF04622.12 ETS74141.1 - 2.9e-93 311.0 1.5 3.4e-93 310.8 1.5 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein PhyH PF05721.13 ETS74144.1 - 2.9e-10 40.7 0.0 8.7e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Zn_clus PF00172.18 ETS74145.1 - 0.0017 18.4 9.2 0.0037 17.3 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 ETS74146.1 - 7.3e-99 331.6 25.9 8.4e-99 331.4 25.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS74146.1 - 1.8e-32 112.6 28.3 1.8e-32 112.6 28.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS74146.1 - 6.3e-08 31.5 0.9 8.9e-08 31.0 0.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) VQ PF05678.14 ETS74146.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 VQ motif Lig_chan PF00060.26 ETS74146.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.1 2 0 0 2 2 2 0 Ligand-gated ion channel COesterase PF00135.28 ETS74148.1 - 3.8e-69 233.9 0.0 1e-63 216.0 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS74148.1 - 2.6e-05 24.2 0.0 9.3e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold ABC_sub_bind PF04392.12 ETS74148.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 ABC transporter substrate binding protein Zip PF02535.22 ETS74149.1 - 2.3e-55 188.2 0.7 4.6e-55 187.2 0.7 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter Methyltransf_11 PF08241.12 ETS74151.1 - 1.3e-10 41.8 0.0 2.2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS74151.1 - 2.2e-08 34.7 0.0 4.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS74151.1 - 4e-05 23.1 0.0 5.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ETS74151.1 - 0.0054 16.6 0.0 0.0076 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS74151.1 - 0.03 13.9 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 ETS74151.1 - 0.067 13.0 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain LIAS_N PF16881.5 ETS74152.1 - 8.5e-19 68.0 0.0 1.8e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 ETS74152.1 - 6.7e-14 52.6 0.1 1.4e-13 51.6 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily PhyH PF05721.13 ETS74154.1 - 1.5e-23 84.2 0.0 2e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_20 PF00728.22 ETS74157.1 - 4.6e-25 88.7 1.6 7.6e-23 81.5 1.6 2.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 ETS74157.1 - 7.4e-07 30.0 0.0 2e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Alpha_L_fucos PF01120.17 ETS74158.1 - 1.8e-80 271.1 1.5 7.5e-80 269.0 1.2 1.8 2 0 0 2 2 2 1 Alpha-L-fucosidase Glyco_hydro_35 PF01301.19 ETS74159.1 - 2.9e-80 270.3 0.6 4.1e-80 269.8 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 ETS74159.1 - 4.2e-05 24.1 0.3 0.00027 21.5 0.0 2.3 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Pmp3 PF01679.17 ETS74161.1 - 3.2e-12 46.5 6.7 4e-12 46.1 6.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Ribosomal_L34e PF01199.18 ETS74161.1 - 0.0019 18.5 0.5 0.0027 18.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e DUF4246 PF14033.6 ETS74162.1 - 2.7e-130 435.5 3.6 3.9e-130 435.0 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) MFS_1 PF07690.16 ETS74163.1 - 5.9e-35 120.8 27.6 5.9e-35 120.8 27.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_5 PF00266.19 ETS74164.1 - 3.3e-10 39.5 0.0 5.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ETS74164.1 - 0.0022 17.3 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 ETS74164.1 - 0.049 12.2 0.0 0.076 11.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme IDO PF01231.18 ETS74165.1 - 6.2e-141 470.1 0.0 7.2e-141 469.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 ETS74165.1 - 0.004 15.9 0.0 0.12 11.1 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1864) TFR_dimer PF04253.15 ETS74165.1 - 0.16 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain Fungal_trans PF04082.18 ETS74166.1 - 1.9e-10 40.3 0.3 3.7e-10 39.3 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS74166.1 - 5.7e-07 29.6 13.2 9.3e-07 28.9 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPX PF03105.19 ETS74166.1 - 1.1 9.1 10.1 4.8 7.0 6.0 2.1 2 0 0 2 2 2 0 SPX domain SSF PF00474.17 ETS74167.1 - 9.4e-21 74.1 32.9 9.4e-21 74.1 32.9 1.7 2 0 0 2 2 2 1 Sodium:solute symporter family DUF2207 PF09972.9 ETS74167.1 - 1 8.1 0.0 1 8.1 0.0 3.6 2 1 0 3 3 3 0 Predicted membrane protein (DUF2207) Bac_luciferase PF00296.20 ETS74168.1 - 1.1e-52 179.4 0.3 1.8e-52 178.7 0.3 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase PNP_UDP_1 PF01048.20 ETS74169.1 - 0.0004 19.7 0.1 0.0023 17.2 0.0 2.0 2 0 0 2 2 2 1 Phosphorylase superfamily UbiA PF01040.18 ETS74170.1 - 7.7e-20 71.2 15.8 7.7e-20 71.2 15.8 1.8 1 1 1 2 2 2 1 UbiA prenyltransferase family PAS_9 PF13426.7 ETS74171.1 - 8.3e-16 58.1 0.0 1.1e-12 48.1 0.0 2.5 2 0 0 2 2 2 2 PAS domain RGS PF00615.19 ETS74171.1 - 6.9e-13 48.9 0.0 2e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS_3 PF08447.12 ETS74171.1 - 0.017 15.4 0.0 0.19 12.0 0.0 2.7 3 1 0 3 3 3 0 PAS fold PAS_4 PF08448.10 ETS74171.1 - 0.064 13.5 0.0 4 7.7 0.0 2.5 2 0 0 2 2 2 0 PAS fold DUF2263 PF10021.9 ETS74172.1 - 2.1e-17 63.8 0.0 5.2e-17 62.6 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) BPL_LplA_LipB PF03099.19 ETS74173.1 - 1e-06 28.7 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Peptidase_C65 PF10275.9 ETS74174.1 - 9.6e-57 192.2 0.0 1.7e-56 191.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase C65 Otubain TFIIA PF03153.13 ETS74174.1 - 0.46 10.4 22.3 0.03 14.3 12.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 ETS74175.1 - 0.43 10.3 10.8 0.59 9.8 10.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FYDLN_acid PF09538.10 ETS74175.1 - 0.62 10.8 11.6 1.2 9.9 11.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) YL1 PF05764.13 ETS74175.1 - 9.8 6.2 13.2 15 5.6 13.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Herpes_UL49_2 PF04823.12 ETS74176.1 - 0.046 13.8 0.9 0.31 11.2 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus UL49 tegument protein DUF4123 PF13503.6 ETS74176.1 - 0.12 12.8 1.0 0.19 12.2 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4123) Gpr1_Fun34_YaaH PF01184.19 ETS74177.1 - 5.5e-32 111.1 19.1 6.8e-32 110.8 19.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family PCI PF01399.27 ETS74178.1 - 2.3e-17 63.4 0.5 6e-17 62.1 0.0 2.0 2 1 0 2 2 2 1 PCI domain TPR_7 PF13176.6 ETS74178.1 - 0.00038 20.3 0.3 0.23 11.6 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ETS74178.1 - 0.0047 17.2 0.3 2.5 8.4 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 ETS74178.1 - 0.0091 15.8 0.3 0.29 11.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ETS74178.1 - 0.037 14.1 3.2 0.17 12.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 ETS74178.1 - 0.093 12.4 0.5 0.75 9.5 0.1 2.5 2 0 0 2 2 2 0 TPR repeat CWC25 PF12542.8 ETS74179.1 - 1.4e-24 87.0 2.4 1.4e-24 87.0 2.4 4.4 2 2 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 ETS74179.1 - 1.9e-13 50.3 2.3 1.9e-13 50.3 2.3 4.1 4 2 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR PTN13_u3 PF16599.5 ETS74180.1 - 0.0073 16.4 0.4 0.013 15.5 0.0 1.6 2 0 0 2 2 2 1 Unstructured linker region on PTN13 protein between PDZ DUF3328 PF11807.8 ETS74181.1 - 6.5e-19 68.6 1.3 6.5e-19 68.6 1.3 1.9 1 1 0 2 2 2 1 Domain of unknown function (DUF3328) Ras PF00071.22 ETS74182.1 - 4.4e-54 182.5 0.0 5e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS74182.1 - 8.4e-22 77.6 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS74182.1 - 4e-10 39.4 0.0 9.6e-10 38.2 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ETS74182.1 - 5.9e-05 22.5 0.0 7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 ETS74182.1 - 0.0035 16.8 0.0 0.0049 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 ETS74182.1 - 0.0039 16.4 0.0 0.012 14.8 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.23 ETS74182.1 - 0.0056 16.8 0.0 0.0088 16.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ETS74182.1 - 0.025 14.1 0.0 0.045 13.3 0.0 1.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ETS74182.1 - 0.057 13.3 0.0 12 5.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 ETS74182.1 - 0.09 13.3 0.0 0.13 12.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Cu-oxidase_3 PF07732.15 ETS74183.1 - 5.8e-45 152.1 4.3 1.3e-41 141.4 0.3 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ETS74183.1 - 2.7e-34 117.9 8.4 3e-30 104.8 0.5 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 ETS74183.1 - 3.8e-27 95.4 1.0 2e-26 93.0 0.2 2.3 2 0 0 2 2 2 1 Multicopper oxidase Romo1 PF10247.9 ETS74184.1 - 1.2e-23 83.3 23.2 1e-17 64.2 7.0 2.2 1 1 1 2 2 2 2 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 ETS74184.1 - 0.0013 19.1 6.5 0.0035 17.7 6.5 1.7 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_YMGG PF13441.6 ETS74184.1 - 0.19 11.5 4.1 0.29 10.9 0.1 2.2 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.6 ETS74184.1 - 1.4 8.7 7.0 1.5 8.7 1.0 2.4 2 0 0 2 2 2 0 Glycine-zipper domain FHA PF00498.26 ETS74185.1 - 6.2e-18 64.9 0.0 1.6e-17 63.6 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ETS74185.1 - 2.3e-05 24.6 0.0 7.5e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF4530 PF15039.6 ETS74185.1 - 0.011 15.9 0.1 0.029 14.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) PI3K_P85_iSH2 PF16454.5 ETS74185.1 - 0.025 14.2 0.1 0.025 14.2 0.1 2.2 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain YhfZ_C PF14503.6 ETS74185.1 - 0.089 12.3 0.3 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 YhfZ C-terminal domain CC2-LZ PF16516.5 ETS74185.1 - 0.22 11.9 11.2 2.9 8.3 0.9 2.7 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FAM76 PF16046.5 ETS74185.1 - 0.42 9.9 3.8 1.6 8.0 0.5 2.3 2 0 0 2 2 2 0 FAM76 protein MCU PF04678.13 ETS74185.1 - 1.7 8.7 3.9 26 4.8 0.2 2.4 2 0 0 2 2 2 0 Mitochondrial calcium uniporter NACHT PF05729.12 ETS74186.1 - 0.013 15.4 0.1 0.027 14.4 0.1 1.6 2 0 0 2 2 2 0 NACHT domain Peptidase_S9 PF00326.21 ETS74187.1 - 0.00023 20.7 0.0 0.0004 19.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ank_2 PF12796.7 ETS74188.1 - 1.3e-66 221.2 0.0 4.1e-13 49.7 0.0 7.5 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS74188.1 - 5.1e-53 176.8 0.2 2.3e-10 40.8 0.1 8.1 6 2 1 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 ETS74188.1 - 1.3e-52 174.0 0.2 6.5e-06 26.4 0.1 12.6 12 1 0 12 12 12 9 Ankyrin repeat Ank_3 PF13606.6 ETS74188.1 - 1.9e-48 156.8 0.0 0.00042 20.6 0.1 13.1 13 0 0 13 13 13 9 Ankyrin repeat Ank_5 PF13857.6 ETS74188.1 - 1.2e-41 140.2 5.9 2.2e-08 34.2 0.1 10.2 6 2 5 11 11 11 7 Ankyrin repeats (many copies) AMNp_N PF10423.9 ETS74188.1 - 0.0047 16.6 0.0 3.5 7.2 0.0 3.2 3 1 1 4 4 4 2 Bacterial AMP nucleoside phosphorylase N-terminus VWA_3_C PF18571.1 ETS74188.1 - 0.022 14.6 0.4 1.1e+02 2.7 0.1 5.1 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain Dioxygenase_C PF00775.21 ETS74190.1 - 1.7e-07 30.8 0.0 2.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase SpaA PF17802.1 ETS74190.1 - 0.033 14.5 1.6 0.075 13.4 0.0 2.3 3 0 0 3 3 3 0 Prealbumin-like fold domain NACHT PF05729.12 ETS74191.1 - 1.2e-06 28.5 0.0 3.6e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS74191.1 - 2.2e-05 24.9 0.4 0.0001 22.7 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 ETS74191.1 - 0.0015 17.8 0.0 0.0039 16.4 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 ETS74191.1 - 0.0036 17.8 0.1 0.013 16.1 0.0 2.0 2 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 ETS74191.1 - 0.0039 17.4 0.4 0.1 12.8 0.0 3.0 3 1 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 ETS74191.1 - 0.0051 16.8 1.2 0.029 14.3 0.0 2.6 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 ETS74191.1 - 0.02 14.6 0.0 0.072 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ETS74191.1 - 0.027 15.0 0.0 0.092 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ETS74191.1 - 0.073 12.8 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 ETS74191.1 - 0.11 12.3 0.0 0.68 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ETS74191.1 - 0.12 12.5 0.3 1.9 8.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ETS74191.1 - 0.13 12.7 0.1 0.41 11.0 0.1 1.9 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 ETS74191.1 - 1.8 9.1 8.5 2 8.8 0.0 2.9 2 1 0 2 2 1 0 AAA domain Ank_4 PF13637.6 ETS74192.1 - 1.4e-34 118.0 7.4 4.2e-08 33.6 0.0 9.6 8 2 2 10 10 10 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS74192.1 - 2.1e-31 108.4 0.7 5.1e-16 59.0 0.0 6.9 6 1 0 6 6 6 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS74192.1 - 5.1e-19 66.4 3.6 0.0017 18.7 0.0 9.5 10 0 0 10 10 10 4 Ankyrin repeat Ank_5 PF13857.6 ETS74192.1 - 3.3e-17 62.3 0.5 0.0052 17.1 0.0 7.9 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Clr5 PF14420.6 ETS74192.1 - 1.2e-14 54.2 0.1 3.3e-14 52.9 0.1 1.8 1 0 0 1 1 1 1 Clr5 domain Ank PF00023.30 ETS74192.1 - 2.3e-09 37.3 5.2 0.016 15.6 0.0 8.1 8 0 0 8 8 8 2 Ankyrin repeat ADH_zinc_N PF00107.26 ETS74193.1 - 9e-10 38.6 0.3 1.8e-09 37.7 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS74193.1 - 1.2e-06 28.3 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Sacchrp_dh_NADP PF03435.18 ETS74193.1 - 0.071 13.4 0.3 0.12 12.6 0.3 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF3278 PF11683.8 ETS74194.1 - 7 6.8 12.1 0.19 11.8 3.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) COesterase PF00135.28 ETS74195.1 - 2.7e-70 237.7 0.8 1.2e-69 235.6 0.8 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS74195.1 - 0.0017 18.3 0.1 0.0065 16.3 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS74195.1 - 0.0032 17.0 0.0 0.0067 15.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family LysM PF01476.20 ETS74196.1 - 2.2e-08 34.0 0.0 0.00013 22.0 0.0 3.2 3 0 0 3 3 3 3 LysM domain HTH_19 PF12844.7 ETS74196.1 - 0.18 11.9 0.0 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain ADH_zinc_N_2 PF13602.6 ETS74197.1 - 1.7e-22 80.9 0.2 3.1e-22 80.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ETS74197.1 - 3.7e-13 49.6 0.2 7.6e-13 48.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS74197.1 - 1.3e-06 28.3 0.0 1.9e-05 24.5 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ETS74197.1 - 0.0057 16.5 0.0 0.015 15.1 0.0 1.7 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase ELFV_dehydrog PF00208.21 ETS74197.1 - 0.0076 16.0 1.9 0.011 15.4 0.5 1.8 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.21 ETS74197.1 - 0.017 14.4 0.2 0.026 13.8 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PALP PF00291.25 ETS74197.1 - 0.053 12.9 1.7 0.14 11.6 1.7 1.6 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme FdhE PF04216.12 ETS74198.1 - 0.036 13.9 2.2 0.057 13.3 2.2 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF5305 PF17231.2 ETS74198.1 - 0.14 11.5 2.4 0.24 10.8 2.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) RFamide_26RFa PF11109.8 ETS74199.1 - 0.077 13.5 0.2 0.17 12.4 0.2 1.5 1 0 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 ALMT PF11744.8 ETS74199.1 - 0.19 10.6 0.6 0.36 9.6 0.6 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Tyrosinase PF00264.20 ETS74200.1 - 4.5e-45 154.7 3.4 6.8e-45 154.1 3.4 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase HET PF06985.11 ETS74201.1 - 7.6e-13 49.1 4.7 9.2e-11 42.3 0.8 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Methyltransf_11 PF08241.12 ETS74202.1 - 1e-17 64.5 0.0 2.1e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS74202.1 - 6.7e-16 58.8 0.0 1.2e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS74202.1 - 1.7e-11 44.7 0.0 3.1e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS74202.1 - 2.7e-11 43.5 0.0 4.9e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS74202.1 - 2.3e-05 24.3 0.0 5.7e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS74202.1 - 8.9e-05 21.9 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ETS74202.1 - 0.0027 17.3 0.0 0.0091 15.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 ETS74202.1 - 0.0058 16.0 0.0 0.0087 15.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Pkinase PF00069.25 ETS74203.1 - 2.9e-10 39.9 0.0 8.5e-10 38.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS74203.1 - 2.2e-05 23.9 0.0 0.00014 21.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_S8 PF00082.22 ETS74204.1 - 1.7e-17 63.6 0.0 3.7e-17 62.5 0.0 1.4 1 1 0 1 1 1 1 Subtilase family CorA PF01544.18 ETS74206.1 - 1.1e-11 44.6 0.7 6.2e-10 38.9 0.3 2.6 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Sua5_yciO_yrdC PF01300.18 ETS74206.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Telomere recombination Flu_M2 PF00599.17 ETS74206.1 - 0.076 13.1 0.1 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 Influenza Matrix protein (M2) PMP22_Claudin PF00822.20 ETS74206.1 - 0.23 11.3 0.5 2 8.3 0.2 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF348 PF03990.14 ETS74206.1 - 0.39 10.5 1.4 2.1 8.1 0.0 2.7 3 0 0 3 3 3 0 G5-linked-Ubiquitin-like domain Atg29_N PF18388.1 ETS74207.1 - 6.7e-27 93.1 1.0 1.2e-26 92.3 1.0 1.4 1 0 0 1 1 1 1 Atg29 N-terminal domain Pinin_SDK_N PF04697.13 ETS74209.1 - 1.7 9.2 4.5 2.6 8.7 0.3 2.7 2 0 0 2 2 2 0 pinin/SDK conserved region WD40 PF00400.32 ETS74210.1 - 3.8e-09 37.0 6.4 0.006 17.4 0.1 4.8 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS74210.1 - 0.0005 20.3 0.1 1.7 9.0 0.0 3.4 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 ETS74210.1 - 0.011 15.3 0.8 0.33 10.5 0.2 2.9 2 1 0 2 2 2 0 PQQ-like domain Pro-kuma_activ PF09286.11 ETS74211.1 - 4.1e-48 163.3 0.9 6.3e-48 162.7 0.9 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ETS74211.1 - 1.1e-06 28.1 2.3 1.8e-06 27.4 2.3 1.2 1 0 0 1 1 1 1 Subtilase family Zn_peptidase PF04228.13 ETS74212.1 - 0.2 11.1 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase TRI12 PF06609.13 ETS74213.1 - 2e-80 270.9 23.4 2.7e-80 270.5 23.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ETS74213.1 - 5.4e-22 78.2 52.9 1.4e-20 73.5 52.4 3.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS74213.1 - 3e-10 39.6 36.2 9.2e-05 21.5 34.3 3.8 2 1 1 3 3 3 2 Sugar (and other) transporter Mid2 PF04478.12 ETS74215.1 - 5.1e-06 26.4 1.1 5.1e-06 26.4 1.1 2.8 2 1 0 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 ETS74215.1 - 0.0017 17.7 3.0 0.0017 17.7 3.0 2.6 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Utp14 PF04615.13 ETS74215.1 - 0.36 9.3 7.7 0.4 9.2 7.7 1.1 1 0 0 1 1 1 0 Utp14 protein DUF4834 PF16118.5 ETS74215.1 - 5.8 7.9 16.2 5.4e+02 1.6 0.0 3.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Dicty_REP PF05086.12 ETS74215.1 - 8.3 4.3 17.2 11 3.8 17.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PBP1_TM PF14812.6 ETS74216.1 - 0.34 11.3 6.5 0.27 11.6 1.5 3.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ORF6C PF10552.9 ETS74216.1 - 4.7 7.3 10.3 1.3 9.2 0.4 3.5 3 0 0 3 3 3 0 ORF6C domain CTP_transf_like PF01467.26 ETS74217.1 - 0.00032 20.9 0.2 0.0023 18.1 0.1 2.4 3 0 0 3 3 3 1 Cytidylyltransferase-like Dzip-like_N PF13815.6 ETS74217.1 - 0.2 11.6 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Amidohydro_1 PF01979.20 ETS74218.1 - 3.7e-27 95.6 0.0 6.4e-27 94.8 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS74218.1 - 7.8e-16 58.6 0.1 5.7e-08 32.7 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Cerato-platanin PF07249.12 ETS74219.1 - 1.5e-57 192.9 6.0 1.7e-57 192.6 6.0 1.1 1 0 0 1 1 1 1 Cerato-platanin M20_dimer PF07687.14 ETS74220.1 - 4.5e-10 39.4 0.1 1.1e-09 38.2 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 ETS74220.1 - 1.3e-07 31.5 0.1 2e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 MFS_1 PF07690.16 ETS74221.1 - 6e-38 130.7 32.1 7.3e-38 130.4 32.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Baculo_PEP_C PF04513.12 ETS74222.1 - 0.018 15.1 0.7 5.3 7.1 0.2 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PUB PF09409.10 ETS74222.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 PUB domain Peptidase_M36 PF02128.15 ETS74223.1 - 1.7e-157 524.3 4.6 2.3e-157 523.9 4.6 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 ETS74223.1 - 6.3e-17 61.1 3.2 1.7e-16 59.8 3.2 1.8 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 ETS74223.1 - 0.089 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M50B PF13398.6 ETS74223.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like IF-2B PF01008.17 ETS74224.1 - 3.6e-26 92.0 0.0 7e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.28 ETS74224.1 - 1.8e-08 34.5 0.0 4.2e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Vps54_N PF10475.9 ETS74224.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Fungal_trans PF04082.18 ETS74225.1 - 5.6e-11 42.0 0.0 1.1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS74225.1 - 1.5e-06 28.2 9.7 1.5e-06 28.2 9.7 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SprT-like PF10263.9 ETS74226.1 - 0.0098 15.7 0.4 0.016 15.0 0.4 1.5 1 1 0 1 1 1 1 SprT-like family ABC_tran PF00005.27 ETS74227.1 - 1.9e-47 161.2 0.2 4.6e-27 95.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 ETS74227.1 - 5.9e-20 71.7 39.9 2.7e-13 49.8 21.5 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 ETS74227.1 - 1.9e-18 67.4 5.1 0.00036 20.5 0.0 4.6 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ETS74227.1 - 1.6e-07 31.0 2.0 0.0054 16.4 0.5 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 ETS74227.1 - 1.6e-06 27.8 3.1 0.52 9.7 0.2 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ETS74227.1 - 3.9e-05 24.3 3.2 0.12 12.9 0.4 2.5 2 0 0 2 2 2 2 AAA domain DUF4162 PF13732.6 ETS74227.1 - 8e-05 23.3 0.0 0.022 15.5 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4162) AAA_30 PF13604.6 ETS74227.1 - 0.002 17.9 0.9 0.87 9.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ETS74227.1 - 0.0021 18.0 1.1 0.15 12.0 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ETS74227.1 - 0.0024 18.3 1.0 1.3 9.4 0.3 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 ETS74227.1 - 0.015 15.0 0.2 11 5.6 0.2 3.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_27 PF13514.6 ETS74227.1 - 0.027 14.1 0.6 6.3 6.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ETS74227.1 - 0.07 12.4 0.6 8.5 5.6 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin SRP54 PF00448.22 ETS74227.1 - 0.12 12.0 0.4 13 5.3 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 ETS74227.1 - 0.12 12.2 0.0 20 5.0 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_22 PF13401.6 ETS74227.1 - 0.14 12.4 0.9 22 5.3 0.2 2.8 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 ETS74227.1 - 0.14 11.1 0.9 0.59 9.1 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 ETS74227.1 - 0.93 9.5 3.1 19 5.2 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain FAM176 PF14851.6 ETS74227.1 - 2.5 7.8 4.1 18 5.0 0.0 2.5 2 0 0 2 2 2 0 FAM176 family DUF2254 PF10011.9 ETS74227.1 - 9.4 4.9 7.9 7.9 5.2 0.4 3.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2254) TACC_C PF05010.14 ETS74228.1 - 0.012 15.4 2.2 0.017 14.9 2.2 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GARP PF16731.5 ETS74228.1 - 0.018 14.7 5.7 0.031 14.0 5.7 1.4 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF4407 PF14362.6 ETS74228.1 - 0.034 13.5 1.2 0.041 13.2 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-K PF11802.8 ETS74228.1 - 0.035 13.7 0.7 0.052 13.1 0.7 1.2 1 0 0 1 1 1 0 Centromere-associated protein K DUF4715 PF15835.5 ETS74228.1 - 0.042 13.9 0.5 0.065 13.3 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) Spc7 PF08317.11 ETS74228.1 - 0.052 12.4 3.1 0.07 12.0 3.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4404 PF14357.6 ETS74228.1 - 0.12 13.1 1.6 0.24 12.1 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Gp58 PF07902.11 ETS74228.1 - 0.15 10.3 2.4 0.22 9.7 2.4 1.2 1 0 0 1 1 1 0 gp58-like protein SHE3 PF17078.5 ETS74228.1 - 0.18 11.5 3.3 0.31 10.7 3.3 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 rve_3 PF13683.6 ETS74228.1 - 0.34 10.7 2.3 0.34 10.7 0.3 2.0 2 0 0 2 2 2 0 Integrase core domain Rad4 PF03835.15 ETS74229.1 - 2.6e-31 108.3 0.1 6.8e-31 106.9 0.1 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 ETS74229.1 - 1.6e-24 86.1 0.1 3.5e-24 85.0 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 ETS74229.1 - 5.2e-20 71.0 0.0 1.1e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 ETS74229.1 - 1.5e-18 67.5 0.1 1.5e-18 67.5 0.1 3.7 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 ETS74229.1 - 0.005 17.3 0.2 0.005 17.3 0.2 3.4 3 1 0 3 3 3 1 Transglutaminase-like superfamily Amidohydro_2 PF04909.14 ETS74230.1 - 4.1e-06 26.8 0.0 1.1e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 ETS74230.1 - 0.0042 16.4 0.1 0.0075 15.6 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase family CoA_binding_2 PF13380.6 ETS74230.1 - 0.012 16.1 0.2 0.046 14.2 0.1 2.0 3 0 0 3 3 3 0 CoA binding domain DUF4928 PF16280.5 ETS74230.1 - 0.065 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4928) HMG_CoA_synt_C PF08540.10 ETS74231.1 - 9.2e-105 350.3 0.4 1.4e-104 349.7 0.4 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 ETS74231.1 - 1.2e-92 308.6 0.8 1.8e-92 308.0 0.8 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal RRM_1 PF00076.22 ETS74232.1 - 6.8e-19 67.5 0.1 6.4e-09 35.5 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ETS74232.1 - 0.041 13.7 0.0 2.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif PXA PF02194.15 ETS74233.1 - 1.9e-52 177.9 0.7 1.9e-52 177.9 0.7 2.3 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 ETS74233.1 - 7.5e-28 97.3 0.1 2.9e-27 95.5 0.1 2.1 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 ETS74233.1 - 1.1e-20 73.7 0.5 2.9e-20 72.4 0.5 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.19 ETS74233.1 - 9.1e-12 45.3 0.2 6e-11 42.7 0.0 2.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain FA_desaturase PF00487.24 ETS74233.1 - 0.84 9.4 5.1 4.5 7.0 3.2 2.2 2 0 0 2 2 2 0 Fatty acid desaturase AA_permease_2 PF13520.6 ETS74234.1 - 2.1e-44 152.0 55.9 2.6e-44 151.7 55.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS74234.1 - 3.7e-27 95.0 51.4 4.6e-27 94.7 51.4 1.0 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.8 ETS74234.1 - 0.27 11.1 0.5 0.7 9.7 0.5 1.7 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Methyltransf_4 PF02390.17 ETS74235.1 - 2.3e-56 189.9 0.0 3e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 ETS74235.1 - 0.00079 20.1 0.0 0.0036 18.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 ETS74235.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 ETS74235.1 - 0.014 14.9 0.0 0.046 13.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 ETS74235.1 - 0.023 15.4 0.0 0.09 13.5 0.0 2.0 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.6 ETS74235.1 - 0.033 14.0 0.0 0.073 12.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 ETS74235.1 - 0.056 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 ETS74235.1 - 0.14 12.9 0.1 1.4 9.6 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 ETS74235.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Pex14_N PF04695.13 ETS74236.1 - 3.7e-39 134.9 2.2 3.7e-39 134.9 2.2 3.2 2 2 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3584 PF12128.8 ETS74236.1 - 0.009 13.6 4.6 0.012 13.2 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) zf-C4H2 PF10146.9 ETS74236.1 - 0.014 15.7 0.1 0.014 15.7 0.1 2.0 2 0 0 2 2 2 0 Zinc finger-containing protein Golgin_A5 PF09787.9 ETS74236.1 - 0.017 14.6 3.8 0.026 14.0 3.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 SHE3 PF17078.5 ETS74236.1 - 0.027 14.2 2.6 0.041 13.6 2.6 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Laminin_II PF06009.12 ETS74236.1 - 0.068 13.2 1.9 0.12 12.3 1.9 1.4 1 0 0 1 1 1 0 Laminin Domain II DUF1043 PF06295.12 ETS74236.1 - 0.11 12.5 0.9 0.22 11.5 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Nup88 PF10168.9 ETS74236.1 - 0.21 9.4 2.3 0.27 9.0 2.3 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF885 PF05960.11 ETS74236.1 - 0.24 11.0 2.8 0.26 10.9 1.6 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) TMPIT PF07851.13 ETS74236.1 - 0.58 9.3 2.1 0.79 8.9 2.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein Sipho_Gp157 PF05565.11 ETS74236.1 - 0.71 9.9 8.1 0.82 9.7 5.6 1.9 1 1 1 2 2 2 0 Siphovirus Gp157 Abhydrolase_3 PF07859.13 ETS74237.1 - 1.4e-39 136.1 0.0 3.7e-39 134.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS74237.1 - 0.0019 17.1 0.0 0.0035 16.3 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase FAD_binding_4 PF01565.23 ETS74238.1 - 1.7e-15 57.0 0.0 2.7e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyrid_oxidase_2 PF13883.6 ETS74239.1 - 1.7e-41 142.0 0.0 2.7e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase WSC PF01822.19 ETS74240.1 - 3.7e-13 49.5 6.1 6.8e-13 48.6 6.1 1.5 1 0 0 1 1 1 1 WSC domain GATA PF00320.27 ETS74241.1 - 1.9e-16 59.4 2.3 3.6e-16 58.5 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 ETS74241.1 - 2e-11 43.5 0.5 3.8e-11 42.6 0.5 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Fungal_trans_2 PF11951.8 ETS74242.1 - 6.1e-35 120.7 2.2 1.2e-34 119.8 2.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS74242.1 - 3.5e-07 30.2 9.5 5.4e-07 29.6 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lambda_tail_I PF06805.12 ETS74242.1 - 0.092 13.1 0.1 0.26 11.7 0.1 1.7 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I MFS_1 PF07690.16 ETS74243.1 - 1.8e-31 109.3 54.8 1.2e-29 103.4 54.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1418 PF07214.12 ETS74243.1 - 0.2 11.5 0.1 0.2 11.5 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1418) TFR_dimer PF04253.15 ETS74244.1 - 2.7e-27 95.3 0.0 5.4e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 ETS74244.1 - 7.2e-21 74.8 0.0 1.3e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ETS74244.1 - 1.3e-09 38.0 0.3 8.2e-09 35.4 0.1 2.4 3 0 0 3 3 3 1 PA domain Peptidase_M20 PF01546.28 ETS74244.1 - 0.0092 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 ETS74244.1 - 0.0095 15.4 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 1 Nicastrin RRM_1 PF00076.22 ETS74245.1 - 0.2 11.5 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDPS PF16715.5 ETS74246.1 - 0.08 12.6 0.2 0.12 12.0 0.2 1.4 1 1 0 1 1 1 0 Cyclodipeptide synthase PetL PF05115.14 ETS74249.1 - 0.09 12.8 0.6 0.09 12.8 0.6 3.4 3 0 0 3 3 3 0 Cytochrome B6-F complex subunit VI (PetL) DUF1980 PF09323.10 ETS74249.1 - 0.094 12.6 3.7 0.11 12.4 1.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF1980) LapA_dom PF06305.11 ETS74249.1 - 2.2 8.1 7.4 12 5.8 1.1 2.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PhoD PF09423.10 ETS74250.1 - 1.8e-105 352.8 5.3 2.4e-105 352.4 5.3 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 ETS74250.1 - 3.3e-30 104.5 0.8 2.1e-29 101.9 0.3 2.3 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 ETS74250.1 - 0.0012 19.4 3.3 0.0034 17.9 3.3 1.8 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Citrate_synt PF00285.21 ETS74251.1 - 1.5e-120 402.6 0.0 1.8e-120 402.3 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF5071 PF16804.5 ETS74255.1 - 1.5e-36 125.3 0.1 6.2e-35 120.0 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF5071) PUL PF08324.11 ETS74255.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 PUL domain Ctr PF04145.15 ETS74257.1 - 2.3e-28 99.7 0.0 3e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family SRF-TF PF00319.18 ETS74258.1 - 3.7e-21 74.3 0.1 5.3e-21 73.8 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Sensor PF13796.6 ETS74259.1 - 1.9 8.5 9.2 1.9 8.5 4.2 2.5 2 1 0 2 2 2 0 Putative sensor adh_short PF00106.25 ETS74260.1 - 2.6e-12 46.6 0.0 6.9e-05 22.4 0.0 2.9 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS74260.1 - 9.6e-09 35.1 0.0 2.5e-05 24.0 0.0 2.6 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS74260.1 - 0.0034 17.3 0.1 0.0087 16.0 0.0 1.7 2 0 0 2 2 2 1 KR domain fn3_2 PF16893.5 ETS74261.1 - 1.4e-38 130.9 0.0 2.3e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 ETS74261.1 - 2.6e-23 81.7 0.7 4e-23 81.1 0.7 1.3 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 ETS74261.1 - 2.2e-12 46.7 0.0 3.8e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 ETS74261.1 - 3.6e-10 40.1 0.0 6e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ETS74261.1 - 3.7e-05 24.1 0.0 9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF3006 PF11213.8 ETS74261.1 - 0.00025 21.2 1.0 0.00085 19.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) fn3 PF00041.21 ETS74261.1 - 0.003 17.9 0.0 0.0091 16.3 0.0 1.8 1 1 0 1 1 1 1 Fibronectin type III domain BUD22 PF09073.10 ETS74261.1 - 0.013 14.9 22.6 0.017 14.5 22.6 1.1 1 0 0 1 1 1 0 BUD22 MCM_bind PF09739.9 ETS74261.1 - 0.41 9.0 2.2 0.55 8.6 2.2 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SAPS PF04499.15 ETS74261.1 - 4.4 6.0 6.5 5.8 5.6 6.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein eIF-1a PF01176.19 ETS74263.1 - 1.5e-20 72.8 0.0 2.1e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DAGK_acc PF00609.19 ETS74263.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase accessory domain WH1 PF00568.23 ETS74264.1 - 1.2e-27 96.0 0.1 1.7e-27 95.6 0.1 1.2 1 0 0 1 1 1 1 WH1 domain CAP_N PF01213.19 ETS74264.1 - 0.00034 20.2 2.4 0.00034 20.2 2.4 10.6 2 1 6 8 8 8 1 Adenylate cyclase associated (CAP) N terminal WH2 PF02205.20 ETS74264.1 - 0.00068 19.4 0.4 0.0015 18.2 0.4 1.6 1 0 0 1 1 1 1 WH2 motif ERCC4 PF02732.15 ETS74266.1 - 2.9e-20 73.1 0.0 5.9e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain CN_hydrolase PF00795.22 ETS74268.1 - 3e-40 138.2 0.0 3.6e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NACHT PF05729.12 ETS74270.1 - 6.4e-07 29.4 0.1 2e-06 27.8 0.1 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS74270.1 - 2.4e-06 28.0 0.0 1.2e-05 25.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Ank_4 PF13637.6 ETS74270.1 - 0.00023 21.7 0.0 0.21 12.2 0.0 3.2 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS74270.1 - 0.00072 19.8 0.1 0.015 15.6 0.0 3.4 3 1 1 4 4 3 1 Ankyrin repeats (many copies) NB-ARC PF00931.22 ETS74270.1 - 0.0048 16.1 0.0 0.013 14.7 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 ETS74270.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ETS74270.1 - 0.022 15.1 0.0 0.058 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 ETS74270.1 - 0.039 14.2 0.0 0.099 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ETS74270.1 - 0.066 13.7 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 ETS74270.1 - 0.1 13.2 0.0 0.41 11.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ETS74270.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ETS74270.1 - 0.17 12.0 0.0 3.8 7.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF676 PF05057.14 ETS74270.1 - 0.18 11.3 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ank PF00023.30 ETS74270.1 - 0.36 11.4 4.0 0.58 10.7 0.1 3.5 5 0 0 5 5 3 0 Ankyrin repeat Sugar_tr PF00083.24 ETS74271.1 - 5.4e-107 358.5 19.1 6.1e-107 358.3 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS74271.1 - 2.9e-27 95.5 42.7 2.2e-24 86.1 18.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 ETS74271.1 - 0.6 10.7 4.5 2.2 8.9 4.5 2.0 1 0 0 1 1 1 0 Phage holin family 2 Ricin_B_lectin PF00652.22 ETS74272.1 - 7.2e-17 61.8 5.1 7.1e-09 36.0 0.9 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 ETS74272.1 - 1e-09 39.0 6.2 6.9e-07 29.9 0.9 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like F-box-like_2 PF13013.6 ETS74273.1 - 0.094 12.7 1.8 0.12 12.3 0.0 2.3 3 1 0 3 3 3 0 F-box-like domain bZIP_2 PF07716.15 ETS74274.1 - 3.1e-05 24.0 6.0 5.9e-05 23.1 6.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ETS74274.1 - 0.00027 21.0 5.1 0.00027 21.0 5.1 1.8 2 0 0 2 2 2 1 bZIP transcription factor MFS_1 PF07690.16 ETS74275.1 - 9.9e-13 47.7 48.8 9.9e-13 47.7 48.8 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS74275.1 - 3.6e-05 22.8 9.9 3.6e-05 22.8 9.9 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter DoxD PF04173.13 ETS74275.1 - 0.37 10.7 6.4 9.9 6.0 6.2 2.5 1 1 1 2 2 2 0 TQO small subunit DoxD WD40 PF00400.32 ETS74277.1 - 1.7e-23 82.4 21.6 2.9e-05 24.8 0.2 6.9 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS74277.1 - 3.7e-12 46.4 5.8 6.3e-05 23.2 0.0 4.3 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS74277.1 - 0.11 11.4 0.3 3.6 6.5 0.0 3.2 2 2 3 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SGL PF08450.12 ETS74278.1 - 0.0021 17.7 0.8 0.38 10.3 0.1 2.9 2 1 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 ETS74278.1 - 0.0051 16.8 0.0 0.95 9.5 0.0 2.9 2 0 0 2 2 2 1 Beta-propeller repeat GSDH PF07995.11 ETS74278.1 - 0.0064 15.8 1.7 0.04 13.2 1.6 2.6 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase DUF726 PF05277.12 ETS74278.1 - 0.071 12.0 2.1 5.8 5.7 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF726) PD40 PF07676.12 ETS74278.1 - 0.097 12.6 5.3 0.46 10.5 0.2 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat NHL PF01436.21 ETS74278.1 - 0.1 12.6 1.5 15 5.9 0.0 4.3 5 1 1 6 6 6 0 NHL repeat WD40 PF00400.32 ETS74278.1 - 1.2 10.1 4.3 49 5.0 0.3 4.1 2 1 1 3 3 3 0 WD domain, G-beta repeat DAO PF01266.24 ETS74279.1 - 1.8e-43 149.5 0.1 2.1e-43 149.3 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS74279.1 - 9.7e-07 28.9 0.1 2.6e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ETS74279.1 - 1.1e-06 28.0 0.0 1.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 ETS74279.1 - 2.2e-06 27.1 0.0 0.0012 18.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS74279.1 - 2.5e-05 23.7 0.0 0.01 15.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS74279.1 - 0.00014 21.9 0.1 0.013 15.5 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 ETS74279.1 - 0.00096 17.9 0.0 0.75 8.4 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Amino_oxidase PF01593.24 ETS74279.1 - 0.00097 18.5 0.0 0.081 12.2 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 ETS74279.1 - 0.0018 17.4 0.1 0.034 13.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 ETS74279.1 - 0.0036 17.8 0.0 0.19 12.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 ETS74279.1 - 0.036 12.8 0.0 0.079 11.7 0.0 1.6 2 0 0 2 2 2 0 MCRA family K_oxygenase PF13434.6 ETS74279.1 - 0.07 12.3 0.0 0.16 11.1 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF4988 PF16378.5 ETS74279.1 - 0.08 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Sacchrp_dh_NADP PF03435.18 ETS74279.1 - 0.16 12.2 0.4 0.75 10.1 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Flavoprotein PF02441.19 ETS74282.1 - 3.5e-22 78.8 0.1 5.5e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.6 ETS74282.1 - 0.13 12.9 0.0 15 6.3 0.0 3.2 2 1 1 3 3 3 0 Ankyrin repeats (many copies) MR_MLE_C PF13378.6 ETS74283.1 - 3.1e-57 193.7 0.0 4.6e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ETS74283.1 - 0.00056 20.1 0.1 0.0016 18.6 0.0 1.7 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 ETS74283.1 - 0.0038 16.4 0.0 0.0058 15.8 0.0 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus DUF1772 PF08592.11 ETS74284.1 - 0.0005 20.4 1.0 0.00084 19.7 1.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) OpgC_C PF10129.9 ETS74284.1 - 0.027 13.3 0.8 0.028 13.3 0.8 1.1 1 0 0 1 1 1 0 OpgC protein zf-Nse PF11789.8 ETS74286.1 - 3.4e-19 68.4 0.4 6e-19 67.6 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 ETS74286.1 - 0.00015 21.5 0.4 0.00027 20.7 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS74286.1 - 0.00064 19.7 0.1 0.0013 18.7 0.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.15 ETS74286.1 - 0.003 17.7 0.0 0.009 16.2 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.7 ETS74286.1 - 0.03 14.6 0.2 0.07 13.4 0.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 ETS74286.1 - 0.036 14.2 0.1 0.068 13.3 0.1 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CCT_2 PF09425.10 ETS74286.1 - 0.054 13.4 1.6 0.2 11.6 1.6 2.0 1 0 0 1 1 1 0 Divergent CCT motif ASPRs PF17641.2 ETS74286.1 - 0.056 13.7 1.9 6 7.2 0.2 2.5 2 0 0 2 2 2 0 Ancylostoma-associated secreted protein related zf-MIZ PF02891.20 ETS74286.1 - 0.068 12.9 0.6 0.12 12.1 0.6 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-ANAPC11 PF12861.7 ETS74286.1 - 0.14 12.2 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MDM10 PF12519.8 ETS74286.1 - 1.4 7.7 4.9 2.8 6.7 4.9 1.6 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 EF_assoc_2 PF08356.12 ETS74287.1 - 3.6e-34 116.6 0.0 7.6e-34 115.6 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 ETS74287.1 - 6.4e-29 99.4 0.2 1.3e-28 98.4 0.2 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 ETS74287.1 - 5.7e-23 81.3 0.0 7.7e-15 54.9 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 ETS74287.1 - 6.8e-14 52.1 0.0 3.6e-09 36.9 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 ETS74287.1 - 3e-07 29.5 3.8 0.0079 15.7 0.2 2.6 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.23 ETS74287.1 - 3.9e-07 30.2 0.0 0.001 19.1 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_6 PF13405.6 ETS74287.1 - 1.3e-06 27.9 3.7 0.019 14.9 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain Dynamin_N PF00350.23 ETS74287.1 - 1.4e-06 28.5 0.9 0.17 11.9 0.0 3.4 2 1 1 3 3 3 2 Dynamin family EF-hand_7 PF13499.6 ETS74287.1 - 3.4e-06 27.4 0.2 0.0036 17.7 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair AAA_16 PF13191.6 ETS74287.1 - 0.00013 22.4 0.1 0.35 11.2 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain GTP_EFTU PF00009.27 ETS74287.1 - 0.00024 20.7 0.0 0.9 9.0 0.2 3.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 ETS74287.1 - 0.0017 17.8 0.0 0.32 10.4 0.0 2.7 2 2 0 2 2 2 1 ADP-ribosylation factor family AAA_29 PF13555.6 ETS74287.1 - 0.002 17.8 0.0 2.1 8.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ETS74287.1 - 0.0022 17.9 0.0 1.7 8.5 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase EF-hand_5 PF13202.6 ETS74287.1 - 0.0039 16.6 5.0 0.23 11.0 1.6 2.6 2 0 0 2 2 2 1 EF hand AAA_22 PF13401.6 ETS74287.1 - 0.0045 17.3 0.0 0.87 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain EF-hand_8 PF13833.6 ETS74287.1 - 0.011 15.5 3.9 0.23 11.4 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair AAA_28 PF13521.6 ETS74287.1 - 0.015 15.6 0.0 4.6 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ETS74287.1 - 0.017 14.8 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain EF-hand_10 PF14788.6 ETS74287.1 - 0.018 14.9 0.6 0.13 12.1 0.1 2.3 2 0 0 2 2 2 0 EF hand RNA_helicase PF00910.22 ETS74287.1 - 0.02 15.3 0.0 0.28 11.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 ETS74287.1 - 0.055 14.0 0.0 2.5 8.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Septin PF00735.18 ETS74287.1 - 0.073 12.3 0.0 0.39 10.0 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 ETS74287.1 - 0.17 11.4 0.0 0.69 9.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 ETS74287.1 - 0.19 10.8 0.1 1.7 7.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF815) WD40 PF00400.32 ETS74288.1 - 4.7e-09 36.7 18.0 0.00025 21.8 0.2 5.6 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS74288.1 - 2.3e-08 34.2 0.0 0.00022 21.4 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 ETS74288.1 - 0.015 14.4 0.0 0.031 13.4 0.0 1.4 1 1 0 1 1 1 0 VID27 C-terminal WD40-like domain eIF2A PF08662.11 ETS74288.1 - 0.029 14.3 0.0 0.12 12.3 0.0 1.9 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 ETS74288.1 - 0.11 11.0 0.0 0.2 10.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Arrestin_C PF02752.22 ETS74289.1 - 2.5e-21 76.5 0.1 1.5e-20 74.0 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ETS74289.1 - 8.7e-14 51.8 0.0 1.7e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ETS74289.1 - 0.00059 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like PH PF00169.29 ETS74290.1 - 0.00044 20.7 0.0 0.00089 19.7 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_17 PF18012.1 ETS74290.1 - 0.078 12.7 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 PH domain Apolipoprotein PF01442.18 ETS74290.1 - 0.21 11.4 3.5 0.12 12.2 0.4 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Pkinase PF00069.25 ETS74292.1 - 2.2e-24 86.3 0.0 2.4e-10 40.2 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 ETS74292.1 - 0.00014 21.2 0.0 0.37 10.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase LANC_like PF05147.13 ETS74293.1 - 9.5e-18 63.9 0.0 2.2e-17 62.7 0.0 1.6 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein DUF5071 PF16804.5 ETS74293.1 - 0.086 13.1 0.2 0.17 12.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) ABC_tran PF00005.27 ETS74294.1 - 2.2e-48 164.3 1.1 7e-23 81.7 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 ETS74294.1 - 3.3e-19 68.7 6.3 3.3e-19 68.7 6.3 4.2 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.6 ETS74294.1 - 2.2e-15 57.3 9.0 0.00087 19.2 0.0 4.5 2 2 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETS74294.1 - 1.1e-10 41.3 4.7 0.0028 17.1 0.0 4.7 5 0 0 5 5 5 4 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ETS74294.1 - 1.4e-07 31.5 0.0 0.015 15.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 ETS74294.1 - 8.5e-07 29.6 0.4 0.032 14.8 0.0 3.4 4 1 0 4 4 2 2 AAA domain RsgA_GTPase PF03193.16 ETS74294.1 - 9.3e-07 28.9 1.0 0.029 14.3 0.1 2.9 2 1 1 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 ETS74294.1 - 2.1e-06 27.3 0.2 0.049 13.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 ETS74294.1 - 1.2e-05 25.9 19.4 0.0051 17.3 0.1 4.7 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.6 ETS74294.1 - 3e-05 24.5 2.6 0.038 14.4 0.1 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA PF00004.29 ETS74294.1 - 7.1e-05 23.2 0.0 0.16 12.4 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS74294.1 - 8.3e-05 22.9 0.1 0.53 10.6 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 ETS74294.1 - 0.00013 22.3 1.3 0.11 12.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ETS74294.1 - 0.00013 22.2 0.1 0.52 10.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 ETS74294.1 - 0.00016 21.5 4.6 0.0054 16.5 0.1 3.4 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 ETS74294.1 - 0.00066 18.7 0.6 0.58 9.1 0.0 2.8 3 0 0 3 3 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 ETS74294.1 - 0.00071 19.4 1.2 1.2 8.9 0.1 3.1 3 0 0 3 3 3 2 AAA domain Roc PF08477.13 ETS74294.1 - 0.0013 18.9 0.0 1.3 9.2 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 ETS74294.1 - 0.0015 18.5 0.2 1.9 8.4 0.1 2.6 2 0 0 2 2 2 2 NACHT domain ATP-synt_ab PF00006.25 ETS74294.1 - 0.0017 18.0 0.1 0.11 12.2 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 ETS74294.1 - 0.0024 17.9 0.0 1.8 8.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 ETS74294.1 - 0.0029 17.5 0.1 0.4 10.6 0.1 2.6 2 0 0 2 2 2 1 NTPase AAA_15 PF13175.6 ETS74294.1 - 0.0037 17.0 17.2 0.069 12.9 0.1 5.2 6 0 0 6 6 6 2 AAA ATPase domain RNA_helicase PF00910.22 ETS74294.1 - 0.005 17.2 0.0 2.9 8.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase cobW PF02492.19 ETS74294.1 - 0.0094 15.5 0.8 1.2 8.7 0.6 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 ETS74294.1 - 0.0095 15.8 0.3 0.25 11.2 0.2 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 ETS74294.1 - 0.0096 15.4 0.0 3 7.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 ETS74294.1 - 0.012 14.8 0.0 2.1 7.5 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain TsaE PF02367.17 ETS74294.1 - 0.018 15.0 0.0 3.6 7.6 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 ETS74294.1 - 0.025 14.6 0.5 3.7 7.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 ETS74294.1 - 0.049 13.2 0.0 3.1 7.4 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 ETS74294.1 - 0.075 13.3 0.6 8.9 6.6 0.3 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 ETS74294.1 - 0.11 12.3 0.2 4.9 7.0 0.0 2.8 3 0 0 3 3 2 0 Rad17 P-loop domain Adeno_IVa2 PF02456.15 ETS74294.1 - 0.15 10.8 0.1 14 4.3 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_27 PF13514.6 ETS74294.1 - 0.21 11.2 6.8 4.1 6.9 0.0 3.6 5 1 0 5 5 3 0 AAA domain Dynamin_N PF00350.23 ETS74294.1 - 0.61 10.1 8.8 2.2 8.3 0.1 4.2 4 1 0 4 4 4 0 Dynamin family AAA_17 PF13207.6 ETS74294.1 - 1.3 9.5 6.8 21 5.5 0.2 4.1 4 0 0 4 4 4 0 AAA domain Zeta_toxin PF06414.12 ETS74294.1 - 2 7.6 6.3 4.8 6.4 0.1 3.4 4 0 0 4 4 3 0 Zeta toxin DUF4315 PF14193.6 ETS74294.1 - 6.9 6.8 11.1 3.4 7.7 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4315) Tubulin PF00091.25 ETS74296.1 - 3.3e-68 229.8 0.0 8.3e-68 228.5 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ETS74296.1 - 4.7e-43 146.4 0.1 7.6e-43 145.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ETS74296.1 - 2.1e-05 24.8 0.0 5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 ETS74296.1 - 0.0025 17.1 0.0 0.026 13.7 0.0 2.0 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 ETS74296.1 - 0.0027 17.4 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Pyr_redox_2 PF07992.14 ETS74297.1 - 2.6e-47 161.5 0.3 3.9e-47 160.9 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 ETS74297.1 - 1.6e-19 70.0 0.0 3.2e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 ETS74297.1 - 1.7e-19 70.2 1.5 1.9e-17 63.6 0.5 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 ETS74297.1 - 1.2e-15 57.6 7.0 2e-11 44.1 5.8 3.0 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.6 ETS74297.1 - 6.9e-12 45.2 0.0 1e-05 25.4 0.0 3.0 3 0 0 3 3 3 2 Rieske-like [2Fe-2S] domain Rieske PF00355.26 ETS74297.1 - 9.7e-12 44.7 0.1 9.1e-06 25.5 0.0 3.5 3 0 0 3 3 3 2 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 ETS74297.1 - 5.5e-10 38.9 0.0 1.1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 ETS74297.1 - 2.2e-08 33.9 0.0 1e-06 28.6 0.0 3.1 3 0 0 3 3 3 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 ETS74297.1 - 1.9e-05 24.1 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS74297.1 - 0.00069 19.6 1.1 2.5 8.1 0.1 3.8 2 2 2 4 4 4 2 FAD-NAD(P)-binding Amino_oxidase PF01593.24 ETS74297.1 - 0.0007 19.0 0.5 0.11 11.7 0.1 2.3 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 ETS74297.1 - 0.13 11.3 1.4 3.3 6.7 0.0 2.8 3 0 0 3 3 3 0 FAD binding domain SUI1 PF01253.22 ETS74298.1 - 6.1e-12 45.9 0.0 9.4e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 adh_short_C2 PF13561.6 ETS74299.1 - 3.4e-51 174.1 0.0 4e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS74299.1 - 4.8e-46 156.7 0.1 6.1e-46 156.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS74299.1 - 1.6e-08 34.7 0.1 3.9e-08 33.4 0.0 1.6 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 ETS74299.1 - 0.038 13.4 0.1 0.067 12.6 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 ETS74299.1 - 0.043 13.7 0.4 0.17 11.7 0.2 1.9 1 1 1 2 2 2 0 YjeF-related protein N-terminus Pkinase PF00069.25 ETS74300.1 - 3e-60 203.8 0.0 3.9e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS74300.1 - 1.5e-31 109.6 0.0 2e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS74300.1 - 3.8e-05 23.2 0.0 6.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ETS74300.1 - 0.0035 17.3 0.8 0.015 15.2 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ETS74300.1 - 0.0036 16.7 0.0 0.0063 15.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ETS74300.1 - 0.026 13.3 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase BCS1_N PF08740.11 ETS74301.1 - 1.3e-46 158.9 0.1 1.3e-46 158.9 0.1 2.6 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 ETS74301.1 - 3e-17 63.3 0.0 1.3e-08 35.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ETS74301.1 - 0.002 18.1 0.0 0.0075 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ETS74301.1 - 0.0056 17.1 0.0 0.0056 17.1 0.0 2.4 1 1 2 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 ETS74301.1 - 0.036 13.8 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 ETS74301.1 - 0.07 12.7 0.2 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ETS74301.1 - 0.073 12.4 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_11 PF13086.6 ETS74301.1 - 0.59 9.9 0.0 0.59 9.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain FPN1 PF06963.12 ETS74302.1 - 2.8e-125 418.3 22.9 3.3e-125 418.1 22.9 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) CrgA PF06781.12 ETS74302.1 - 0.058 13.5 2.2 0.098 12.7 0.3 2.4 2 1 0 2 2 2 0 Cell division protein CrgA TFIIA PF03153.13 ETS74303.1 - 0.011 15.8 22.7 0.012 15.7 22.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 ETS74303.1 - 0.038 14.0 12.6 0.043 13.8 12.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.10 ETS74303.1 - 0.14 10.8 7.7 0.15 10.7 7.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LAP1C PF05609.12 ETS74303.1 - 0.19 10.8 8.8 0.21 10.6 8.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 ETS74303.1 - 0.27 8.3 6.8 0.27 8.3 6.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Spt20 PF12090.8 ETS74303.1 - 0.27 10.8 24.2 0.37 10.4 24.2 1.3 1 0 0 1 1 1 0 Spt20 family Tmemb_cc2 PF10267.9 ETS74303.1 - 0.31 10.1 8.7 0.37 9.9 8.7 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF4407 PF14362.6 ETS74303.1 - 0.63 9.3 3.4 0.81 9.0 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hid1 PF12722.7 ETS74303.1 - 0.73 7.9 7.5 0.8 7.8 7.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4614 PF15391.6 ETS74303.1 - 1 9.3 17.8 0.31 11.0 15.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Neur_chan_memb PF02932.16 ETS74303.1 - 1.2 9.1 5.2 1.4 8.9 5.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 ETS74303.1 - 1.2 7.8 11.7 1.5 7.5 11.7 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 ETS74303.1 - 1.4 8.1 6.5 1.6 7.8 6.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Band_3_cyto PF07565.13 ETS74303.1 - 2.6 7.8 11.7 3.5 7.3 11.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF5427 PF10310.9 ETS74303.1 - 3.6 6.5 13.2 5 6.0 13.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Pex14_N PF04695.13 ETS74303.1 - 3.7 8.2 31.5 8 7.1 31.6 1.6 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.9 ETS74303.1 - 3.8 5.7 16.4 4.2 5.5 16.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 ETS74303.1 - 4.7 6.1 10.8 5.6 5.8 10.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2207 PF09972.9 ETS74304.1 - 0.088 11.6 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4229 PF14012.6 ETS74304.1 - 0.18 12.0 0.4 0.32 11.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF4078 PF13300.6 ETS74305.1 - 5.5e-29 100.3 12.6 5.5e-29 100.3 12.6 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) VIR_N PF15912.5 ETS74305.1 - 3.1 7.3 11.7 3.7 7.1 7.9 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal Homoserine_dh PF00742.19 ETS74306.1 - 6.7e-52 175.9 0.0 9.1e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 ETS74306.1 - 2.1e-19 70.3 0.0 4.8e-19 69.2 0.0 1.6 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain IGPS PF00218.21 ETS74306.1 - 0.02 14.1 0.1 0.03 13.5 0.1 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase adh_short PF00106.25 ETS74307.1 - 5e-05 22.9 0.0 0.085 12.3 0.0 3.1 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.10 ETS74307.1 - 0.19 11.6 0.2 0.44 10.4 0.0 1.7 2 0 0 2 2 2 0 KR domain MFS_1 PF07690.16 ETS74308.1 - 2.4e-26 92.5 36.2 3.4e-26 92.0 36.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS74308.1 - 0.078 11.8 21.8 0.0094 14.8 3.1 3.0 1 1 1 3 3 3 0 MFS_1 like family UCR_hinge PF02320.16 ETS74309.1 - 2.2e-28 98.2 9.1 2.2e-28 98.2 9.1 2.0 2 1 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein CDC45 PF02724.14 ETS74309.1 - 0.00013 20.4 16.9 0.00016 20.1 16.9 1.0 1 0 0 1 1 1 1 CDC45-like protein Mpp10 PF04006.12 ETS74309.1 - 0.024 13.1 27.2 0.028 12.9 27.2 1.1 1 0 0 1 1 1 0 Mpp10 protein RPN2_C PF18004.1 ETS74309.1 - 0.043 13.7 21.3 0.067 13.1 21.3 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 ETS74309.1 - 0.11 10.7 30.4 0.11 10.7 30.4 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 ETS74309.1 - 0.26 10.6 28.3 0.29 10.4 28.3 1.0 1 0 0 1 1 1 0 BUD22 RR_TM4-6 PF06459.12 ETS74309.1 - 0.29 10.9 24.2 0.36 10.6 24.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 ETS74309.1 - 0.38 10.1 27.8 0.44 9.9 27.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SpoIIIAH PF12685.7 ETS74309.1 - 0.72 9.7 15.9 0.86 9.4 15.9 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Tim54 PF11711.8 ETS74309.1 - 0.73 8.6 18.8 0.85 8.3 18.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Mitofilin PF09731.9 ETS74309.1 - 0.99 8.2 22.4 1.1 8.0 22.4 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF5427 PF10310.9 ETS74309.1 - 1.1 8.2 18.0 1.1 8.1 18.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CCSAP PF15748.5 ETS74309.1 - 1.1 9.4 19.7 1.3 9.1 19.7 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Vfa1 PF08432.10 ETS74309.1 - 1.6 9.1 21.8 2.1 8.7 21.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SAPS PF04499.15 ETS74309.1 - 1.6 7.4 12.9 1.7 7.3 12.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2828 PF11443.8 ETS74309.1 - 1.7 6.7 9.0 1.9 6.5 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 ETS74309.1 - 1.9 7.2 18.1 2.2 7.0 18.1 1.0 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 ETS74309.1 - 2.3 7.2 10.4 2.5 7.0 10.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 MDM1 PF15501.6 ETS74309.1 - 2.4 7.2 24.5 3.1 6.8 24.5 1.2 1 0 0 1 1 1 0 Nuclear protein MDM1 SpoIIP PF07454.11 ETS74309.1 - 2.7 7.4 16.6 3.9 6.8 16.6 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Merozoite_SPAM PF07133.11 ETS74309.1 - 3.9 7.4 45.2 5 7.1 45.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) LAP1C PF05609.12 ETS74309.1 - 4.2 6.3 17.2 4.6 6.2 17.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF913 PF06025.12 ETS74309.1 - 4.7 6.1 13.4 5.7 5.8 13.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Raftlin PF15250.6 ETS74309.1 - 4.9 5.8 14.4 5.4 5.6 14.4 1.0 1 0 0 1 1 1 0 Raftlin Neur_chan_memb PF02932.16 ETS74309.1 - 4.9 7.1 9.6 5.5 7.0 9.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4045 PF13254.6 ETS74309.1 - 5.3 6.6 18.7 6.2 6.3 18.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) BORG_CEP PF14957.6 ETS74309.1 - 6.7 7.9 10.8 8.8 7.5 10.8 1.3 1 0 0 1 1 1 0 Cdc42 effector DDRGK PF09756.9 ETS74309.1 - 7.2 6.2 29.5 11 5.6 29.5 1.3 1 0 0 1 1 1 0 DDRGK domain NPR3 PF03666.13 ETS74309.1 - 7.3 5.3 16.0 8 5.1 16.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Drf_GBD PF06371.13 ETS74311.1 - 2.5e-13 50.0 0.3 3.8e-12 46.2 0.3 2.2 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Calc_CGRP_IAPP PF00214.19 ETS74312.1 - 0.07 13.5 0.0 0.082 13.3 0.0 1.2 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family Suc_Fer-like PF06999.12 ETS74313.1 - 3.5e-68 229.3 0.0 4.5e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Acyltransferase PF01553.21 ETS74314.1 - 5.5e-11 42.2 0.0 5.1e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase BRAP2 PF07576.12 ETS74315.1 - 4.6e-29 100.6 0.0 7.6e-29 99.9 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 ETS74315.1 - 5.2e-19 68.3 3.5 1.5e-18 66.8 3.4 1.9 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 ETS74315.1 - 2.6e-09 37.3 9.5 2.6e-09 37.3 9.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 ETS74315.1 - 1.9e-07 30.8 9.3 4.7e-07 29.5 9.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ETS74315.1 - 2.1e-06 27.3 4.6 9e-06 25.3 4.6 2.2 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 ETS74315.1 - 2.4e-06 27.3 7.5 7.2e-06 25.8 7.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS74315.1 - 4.9e-06 26.5 6.4 6.2e-05 22.9 6.8 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ETS74315.1 - 6.5e-05 22.7 6.9 6.5e-05 22.7 6.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ETS74315.1 - 0.00026 20.9 8.1 0.00026 20.9 8.1 2.1 2 0 0 2 2 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ETS74315.1 - 0.00048 20.4 6.8 0.00048 20.4 6.8 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 ETS74315.1 - 0.0056 16.5 3.1 0.018 14.9 3.1 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein FAM76 PF16046.5 ETS74315.1 - 0.048 13.0 5.4 0.093 12.1 5.4 1.4 1 0 0 1 1 1 0 FAM76 protein Prok-RING_4 PF14447.6 ETS74315.1 - 0.085 12.7 21.4 0.018 14.9 12.3 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Baculo_RING PF05883.11 ETS74315.1 - 0.1 12.6 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain DUF2203 PF09969.9 ETS74315.1 - 0.11 13.3 4.2 0.17 12.6 3.4 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) zf-UBP_var PF17807.1 ETS74315.1 - 0.12 12.1 0.1 0.12 12.1 0.1 1.8 2 0 0 2 2 1 0 Variant UBP zinc finger Fib_alpha PF08702.10 ETS74315.1 - 0.3 11.3 3.4 0.3 11.3 1.8 1.8 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family zf-RING_4 PF14570.6 ETS74315.1 - 0.35 10.7 6.5 0.79 9.6 6.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain YabA PF06156.13 ETS74315.1 - 0.44 11.2 11.5 0.42 11.3 4.0 2.4 1 1 1 2 2 2 0 Initiation control protein YabA CENP-H PF05837.12 ETS74315.1 - 0.86 10.0 18.7 0.24 11.8 5.9 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Prefoldin_2 PF01920.20 ETS74315.1 - 1 9.3 10.4 0.61 10.1 7.9 2.0 1 1 0 1 1 1 0 Prefoldin subunit DUF1664 PF07889.12 ETS74315.1 - 1.1 9.3 4.6 14 5.8 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 ETS74315.1 - 1.3 9.2 22.8 4.3 7.5 22.5 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 ETS74315.1 - 1.6 8.0 11.8 2.6 7.3 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 ETS74315.1 - 2.4 8.6 15.4 0.26 11.7 4.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) PRKG1_interact PF15898.5 ETS74315.1 - 2.9 8.9 13.3 0.72 10.8 8.5 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Sec34 PF04136.15 ETS74315.1 - 3.3 7.6 7.0 5 7.0 1.2 2.4 1 1 1 2 2 2 0 Sec34-like family Fez1 PF06818.15 ETS74315.1 - 4.6 7.6 13.8 8.8 6.7 13.8 1.5 1 0 0 1 1 1 0 Fez1 ZapB PF06005.12 ETS74315.1 - 5.2 7.6 15.9 11 6.5 6.2 2.7 1 1 1 2 2 2 0 Cell division protein ZapB DUF4201 PF13870.6 ETS74315.1 - 6.3 6.5 13.7 0.58 9.9 8.1 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) SKA2 PF16740.5 ETS74315.1 - 6.6 6.6 9.4 5.7 6.8 3.2 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF3450 PF11932.8 ETS74315.1 - 6.8 5.9 15.0 10 5.4 11.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ubiquitin PF00240.23 ETS74316.1 - 4.4e-135 439.7 20.4 3.3e-33 113.3 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 ETS74316.1 - 6.6e-64 211.7 21.0 2e-15 56.4 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ETS74316.1 - 8.1e-23 80.7 10.7 0.00043 20.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 ETS74316.1 - 1.7e-16 59.9 3.0 0.027 14.4 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 ETS74316.1 - 3.9e-15 56.0 8.2 0.028 14.8 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 ETS74316.1 - 2.1e-14 53.6 2.6 0.12 12.4 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ETS74316.1 - 5.6e-13 49.4 1.4 0.37 11.4 0.0 4.2 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 ETS74316.1 - 5.2e-11 42.7 0.8 0.52 10.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 ETS74316.1 - 3.7e-07 30.1 24.0 16 5.6 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 ETS74316.1 - 2.9e-06 26.8 0.4 1.8 7.8 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 ETS74316.1 - 3.8e-06 27.0 2.5 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 ETS74316.1 - 7.1e-06 26.3 0.0 30 5.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 ETS74316.1 - 1.2e-05 25.0 4.7 10 6.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain Big_7 PF17957.1 ETS74316.1 - 4e-05 24.3 0.1 52 4.7 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 ETS74316.1 - 0.00014 21.9 4.3 7.1 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 ETS74316.1 - 0.00042 19.8 0.0 23 4.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) YcgR_2 PF12945.7 ETS74316.1 - 0.00091 19.3 6.2 29 4.9 0.1 4.3 4 0 0 4 4 4 0 Flagellar protein YcgR DUF493 PF04359.14 ETS74316.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 ETS74316.1 - 0.0037 16.9 0.0 1e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 ETS74316.1 - 0.0052 17.4 1.0 1.4e+02 3.1 0.0 4.2 4 0 0 4 4 4 0 ACT domain ORF11CD3 PF10549.9 ETS74316.1 - 0.0068 16.5 0.0 91 3.3 0.0 4.3 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 ETS74316.1 - 0.11 12.7 5.8 1.1e+02 3.1 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Baculo_p48 PF04878.13 ETS74316.1 - 0.12 11.2 0.0 61 2.4 0.0 3.0 3 0 0 3 3 3 0 Baculovirus P48 protein Tash_PEST PF07708.11 ETS74316.1 - 0.14 12.4 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Myosin_N PF02736.19 ETS74316.1 - 0.23 11.3 6.3 1.1e+02 2.8 0.0 5.2 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain HAMP_N3 PF18575.1 ETS74316.1 - 0.23 11.0 1.5 2e+02 1.6 0.0 3.9 4 0 0 4 4 4 0 HAMP N-terminal domain 3 PI3K_p85B PF02192.16 ETS74316.1 - 1.9 8.3 9.3 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain VirB3 PF05101.13 ETS74317.1 - 3 8.2 7.5 2.8 8.3 0.1 2.7 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein Zn_clus PF00172.18 ETS74318.1 - 0.014 15.5 7.2 0.029 14.5 7.2 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Gag_p12 PF01141.18 ETS74318.1 - 3.9 7.9 10.0 9.7 6.6 4.5 2.7 1 1 1 2 2 2 0 Gag polyprotein, inner coat protein p12 Prenyltrans PF00432.21 ETS74319.1 - 2.5e-39 132.7 25.7 4.7e-09 35.8 0.3 6.4 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 ETS74319.1 - 0.052 12.7 0.1 0.16 11.0 0.1 1.8 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain DND1_DSRM PF14709.7 ETS74320.1 - 0.0038 17.5 0.1 0.0065 16.7 0.1 1.4 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 ETS74320.1 - 0.03 15.0 0.0 0.075 13.8 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif NTP_transferase PF00483.23 ETS74321.1 - 8.4e-51 172.9 0.0 1.9e-50 171.8 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 ETS74321.1 - 5.1e-14 51.4 5.2 1.1e-10 40.8 0.4 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ETS74321.1 - 1.4e-11 45.0 0.0 1.8e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ETS74321.1 - 1.4e-06 27.9 1.6 1.4e-06 27.9 1.6 3.2 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 ETS74321.1 - 0.0033 15.6 0.1 0.0095 14.1 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) IspD PF01128.19 ETS74321.1 - 0.014 15.1 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase FGGY_C PF02782.16 ETS74322.1 - 1.6e-71 240.1 0.1 2.5e-71 239.5 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 ETS74322.1 - 9.5e-65 218.6 0.0 1.3e-64 218.1 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Collagen PF01391.18 ETS74322.1 - 0.11 12.3 3.3 0.28 11.0 3.3 1.6 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF2639 PF11121.8 ETS74322.1 - 0.13 12.3 0.3 0.56 10.3 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2639) Nramp PF01566.18 ETS74324.1 - 2.6e-87 293.1 18.2 2.6e-87 293.1 18.2 2.4 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein PEMT PF04191.13 ETS74325.1 - 1.6e-34 118.5 4.4 4.4e-34 117.1 2.4 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase RXT2_N PF08595.11 ETS74326.1 - 9.1e-41 139.5 0.0 9.1e-41 139.5 0.0 3.0 3 0 0 3 3 3 1 RXT2-like, N-terminal DUF4167 PF13763.6 ETS74326.1 - 0.43 10.8 2.6 0.32 11.2 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4167) Gryzun PF07919.12 ETS74327.1 - 5.9e-207 689.1 0.0 7.1e-207 688.8 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 ETS74327.1 - 8.5e-83 277.9 8.5 7.9e-78 261.6 8.0 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 HisG PF01634.18 ETS74327.1 - 0.0045 17.0 0.0 0.0092 16.0 0.0 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase Gryzun-like PF12742.7 ETS74327.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Tyrosinase PF00264.20 ETS74328.1 - 3.4e-46 158.3 4.0 5.8e-46 157.6 4.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 ETS74328.1 - 2.1e-05 25.2 0.0 0.00023 21.8 0.0 2.2 1 1 0 1 1 1 1 Tyosinase C-terminal domain DHDPS PF00701.22 ETS74329.1 - 9.9e-38 129.5 0.0 1.4e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Amidase PF01425.21 ETS74330.1 - 3.2e-79 267.0 0.6 4.2e-79 266.6 0.6 1.1 1 0 0 1 1 1 1 Amidase GST_N_4 PF17172.4 ETS74332.1 - 2.7e-20 72.9 0.3 6.6e-20 71.7 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 ETS74332.1 - 3.7e-07 29.9 0.1 5.4e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 ETS74332.1 - 0.00031 21.0 0.0 0.00097 19.4 0.0 1.8 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 ETS74332.1 - 0.0019 18.2 0.2 0.0044 17.0 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BLM10_mid PF16507.5 ETS74333.1 - 1.1e-203 677.7 0.0 1.9e-203 676.9 0.0 1.4 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 ETS74333.1 - 1.3e-28 98.7 0.0 4.9e-28 96.9 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 ETS74333.1 - 4.9e-22 78.0 0.0 1.6e-21 76.4 0.0 2.0 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal MFS_1 PF07690.16 ETS74335.1 - 1.7e-21 76.6 64.4 1.9e-15 56.7 31.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mannosyl_trans2 PF04188.13 ETS74337.1 - 2.1e-52 178.9 10.0 2.8e-52 178.5 10.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) PMT_2 PF13231.6 ETS74337.1 - 4.2e-09 36.8 1.6 4.2e-09 36.8 1.6 2.6 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase 2OG-FeII_Oxy PF03171.20 ETS74338.1 - 6.7e-12 45.8 0.0 1.6e-11 44.6 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ETS74338.1 - 2.6e-11 44.3 0.0 4.7e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal UbiA PF01040.18 ETS74339.1 - 5.5e-22 78.3 9.8 5.5e-22 78.3 9.8 1.6 1 1 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.22 ETS74340.1 - 4.3e-52 177.4 0.0 5.6e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 ETS74343.1 - 3.7e-30 105.2 0.0 6.7e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 4HBT_2 PF13279.6 ETS74344.1 - 1.1e-05 25.9 0.0 1.2e-05 25.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF1772 PF08592.11 ETS74345.1 - 1.2 9.5 8.9 7.5 6.9 6.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF4293 PF14126.6 ETS74345.1 - 3.2 8.0 14.0 0.21 11.8 7.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Cation_ATPase_C PF00689.21 ETS74345.1 - 7.6 6.2 18.7 4.2 7.0 10.7 2.6 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus NMT1 PF09084.11 ETS74346.1 - 2.5e-10 40.7 0.1 3.4e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 ETS74346.1 - 0.00027 20.6 0.7 0.00045 19.9 0.7 1.4 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein OpuAC PF04069.12 ETS74346.1 - 0.0011 18.6 0.1 0.0019 17.9 0.1 1.3 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system NACHT PF05729.12 ETS74348.1 - 1.7e-08 34.6 0.2 4.3e-08 33.2 0.2 1.7 1 1 0 1 1 1 1 NACHT domain SesA PF17107.5 ETS74348.1 - 5.3e-07 29.8 1.7 8.1e-07 29.3 0.4 2.1 2 0 0 2 2 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NB-ARC PF00931.22 ETS74348.1 - 0.0006 19.1 0.0 0.0033 16.6 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 ETS74348.1 - 0.0007 20.1 0.3 0.0052 17.3 0.0 2.5 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 ETS74348.1 - 0.0014 19.1 0.0 0.0014 19.1 0.0 2.7 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS74348.1 - 0.002 18.4 6.1 0.02 15.2 0.0 3.8 3 1 1 4 4 4 1 AAA domain Ploopntkinase3 PF18751.1 ETS74348.1 - 0.0022 17.9 0.0 0.01 15.7 0.0 2.1 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 ETS74348.1 - 0.0027 18.1 0.0 0.0067 16.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase DUF2075 PF09848.9 ETS74348.1 - 0.0059 15.9 0.0 0.017 14.4 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.23 ETS74348.1 - 0.0069 16.5 0.0 0.024 14.7 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 ETS74348.1 - 0.01 16.3 0.4 0.78 10.2 0.0 3.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 ETS74348.1 - 0.011 15.0 0.0 0.038 13.2 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 ETS74348.1 - 0.014 15.9 0.0 0.12 12.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 ETS74348.1 - 0.019 14.7 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ETS74348.1 - 0.02 15.4 0.9 0.15 12.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ETS74348.1 - 0.03 14.0 0.1 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ETS74348.1 - 0.035 14.0 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ATP_bind_1 PF03029.17 ETS74348.1 - 0.039 13.7 0.9 0.38 10.5 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 ETS74348.1 - 0.058 13.5 0.1 0.29 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Acp26Ab PF05777.12 ETS74348.1 - 0.091 13.4 0.0 0.22 12.2 0.0 1.6 1 0 0 1 1 1 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) SMC_N PF02463.19 ETS74348.1 - 0.15 11.5 0.0 2 7.8 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF5601 PF18151.1 ETS74348.1 - 0.15 12.4 0.4 1.5 9.2 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) Arginase PF00491.21 ETS74349.1 - 5e-23 82.0 0.0 6.1e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family Transketolase_C PF02780.20 ETS74349.1 - 0.01 15.7 0.0 0.03 14.2 0.0 1.7 2 0 0 2 2 2 0 Transketolase, C-terminal domain Ldh_2 PF02615.14 ETS74350.1 - 6.6e-124 413.4 0.1 7.5e-124 413.2 0.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Pkinase PF00069.25 ETS74351.1 - 7.5e-26 91.1 0.0 5.3e-25 88.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS74351.1 - 0.00012 21.4 0.0 0.0014 17.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Metallophos PF00149.28 ETS74353.1 - 1.4e-09 38.8 1.7 2.4e-09 38.0 1.7 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ETS74353.1 - 7.9e-08 32.7 0.4 6.4e-07 29.7 0.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain F-box PF00646.33 ETS74354.1 - 0.0015 18.4 0.4 0.0039 17.0 0.1 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ETS74354.1 - 0.0032 17.3 0.1 0.01 15.7 0.1 2.0 1 0 0 1 1 1 1 F-box-like DUF982 PF06169.12 ETS74354.1 - 0.16 12.0 1.1 6.1 7.0 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF982) TauD PF02668.16 ETS74355.1 - 4.1e-11 43.2 3.0 7.2e-10 39.1 3.0 2.1 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 ETS74355.1 - 0.00053 19.2 0.0 0.00097 18.3 0.0 1.3 1 0 0 1 1 1 1 CsiD ArgoL2 PF16488.5 ETS74355.1 - 0.14 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Argonaute linker 2 domain MFS_1 PF07690.16 ETS74356.1 - 5.2e-44 150.6 50.7 1.4e-43 149.2 49.3 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS74356.1 - 2.2e-15 56.2 23.1 2.7e-15 55.8 23.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS74356.1 - 1.7e-11 43.7 14.4 1.7e-11 43.7 14.4 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter UDPG_MGDP_dh_N PF03721.14 ETS74357.1 - 8e-48 162.5 0.2 1.3e-28 99.8 0.2 2.4 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 ETS74357.1 - 2.4e-31 107.8 0.0 6.2e-31 106.5 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 ETS74357.1 - 4.4e-22 78.5 0.0 3.5e-17 62.7 0.0 2.9 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 ETS74357.1 - 0.00042 20.5 0.0 0.29 11.3 0.1 2.7 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 ETS74357.1 - 0.00071 19.8 0.0 0.002 18.4 0.0 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ETS74357.1 - 0.014 15.4 0.0 1.9 8.5 0.0 2.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 ETS74357.1 - 0.029 14.2 0.0 0.099 12.5 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 ETS74357.1 - 0.029 14.0 0.0 0.075 12.7 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 ETS74357.1 - 0.13 12.6 0.4 0.7 10.2 0.0 2.4 3 0 0 3 3 3 0 TrkA-N domain tRNA-synt_1 PF00133.22 ETS74358.1 - 5.5e-216 718.5 0.0 7.1e-215 714.8 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ETS74358.1 - 6.2e-30 104.2 0.9 2e-29 102.5 0.9 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ETS74358.1 - 2e-13 49.9 0.9 4.7e-06 25.6 0.2 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 ETS74358.1 - 2.7e-12 46.6 1.0 9e-08 31.8 0.0 3.1 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Peptidase_M28 PF04389.17 ETS74359.1 - 8.3e-21 74.6 0.2 2.3e-20 73.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 TFR_dimer PF04253.15 ETS74359.1 - 1.8e-12 47.4 0.0 4.6e-12 46.1 0.0 1.7 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain PA PF02225.22 ETS74359.1 - 3.7e-09 36.5 0.0 1.3e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ETS74359.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Nicastrin PF05450.15 ETS74359.1 - 0.022 14.2 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Nicastrin Glyco_hydro_36N PF16875.5 ETS74359.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 36 N-terminal domain Glycos_transf_2 PF00535.26 ETS74361.1 - 2.1e-25 89.5 0.1 4.3e-25 88.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ETS74361.1 - 1.3e-09 38.3 1.0 3.4e-09 36.9 0.0 2.1 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ETS74361.1 - 3.2e-06 26.8 0.0 4.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 ETS74361.1 - 2.9e-05 24.5 0.0 0.00011 22.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 MFS_1 PF07690.16 ETS74362.1 - 1.1e-21 77.1 32.8 5.4e-13 48.6 7.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4205 PF13898.6 ETS74362.1 - 0.22 10.4 0.4 0.34 9.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4205) ABC_tran PF00005.27 ETS74363.1 - 5e-46 156.6 0.2 4.6e-26 92.0 0.1 3.5 4 1 0 4 4 3 2 ABC transporter ABC_membrane PF00664.23 ETS74363.1 - 3.1e-33 115.6 43.2 4.3e-30 105.3 18.6 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 ETS74363.1 - 3.2e-10 39.8 1.4 0.048 13.1 0.1 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETS74363.1 - 7.5e-08 32.5 0.4 0.19 11.5 0.0 4.3 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ETS74363.1 - 4.9e-06 26.6 0.5 0.0033 17.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ETS74363.1 - 1.2e-05 25.4 0.3 0.021 14.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 ETS74363.1 - 1.4e-05 25.4 0.2 0.19 12.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ETS74363.1 - 0.00039 20.1 0.2 0.99 9.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 ETS74363.1 - 0.0018 18.4 1.5 0.19 11.7 0.0 2.9 3 0 0 3 3 3 1 Dynamin family AAA_16 PF13191.6 ETS74363.1 - 0.0019 18.6 0.2 0.21 11.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 ETS74363.1 - 0.0022 17.5 0.1 1.5 8.3 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 ETS74363.1 - 0.0087 15.3 0.4 0.55 9.5 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin DEAD PF00270.29 ETS74363.1 - 0.0092 15.8 0.1 2.3 7.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.18 ETS74363.1 - 0.01 15.2 0.2 0.6 9.4 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 ETS74363.1 - 0.013 16.0 0.0 5.4 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ETS74363.1 - 0.015 15.0 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 ETS74363.1 - 0.02 14.0 0.7 0.95 8.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 ETS74363.1 - 0.04 13.6 0.1 1.1 9.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 ETS74363.1 - 0.042 13.4 1.1 4 7.0 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 ETS74363.1 - 0.053 13.3 0.1 4.9 6.8 0.0 2.6 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.17 ETS74363.1 - 0.062 13.4 0.7 0.72 9.9 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain SbcCD_C PF13558.6 ETS74363.1 - 0.071 13.3 0.0 8.6 6.7 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 ETS74363.1 - 0.093 13.2 0.2 2 8.8 0.0 3.1 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) SH3BGR PF04908.15 ETS74363.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein AAA_24 PF13479.6 ETS74363.1 - 0.11 12.2 0.0 0.48 10.1 0.0 2.1 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 ETS74363.1 - 1.1 9.1 4.1 2.8 7.8 0.1 3.0 3 0 0 3 3 3 0 NACHT domain MFS_1 PF07690.16 ETS74364.1 - 2.2e-08 33.4 22.2 2e-07 30.3 17.9 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 ETS74364.1 - 0.00023 19.9 1.0 0.00023 19.9 1.0 3.0 3 1 0 3 3 3 1 MFS/sugar transport protein DUF3328 PF11807.8 ETS74365.1 - 3.4e-13 49.9 1.0 8.9e-13 48.5 1.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) ProQ PF04352.13 ETS74366.1 - 1.5e-05 24.8 7.5 1.3 8.9 0.0 4.9 4 1 1 5 5 5 2 ProQ/FINO family zf-C3H1 PF10650.9 ETS74366.1 - 0.00023 20.8 4.7 17 5.3 0.0 5.1 5 0 0 5 5 5 0 Putative zinc-finger domain Putative_PNPOx PF01243.20 ETS74366.1 - 0.00042 20.4 1.2 13 6.0 0.0 4.6 2 2 3 5 5 5 1 Pyridoxamine 5'-phosphate oxidase IceA2 PF05862.11 ETS74366.1 - 0.0012 18.8 3.6 73 3.4 0.1 5.0 5 0 0 5 5 5 0 Helicobacter pylori IceA2 protein Big_2 PF02368.18 ETS74366.1 - 0.005 16.7 7.1 3.2 7.7 0.1 4.8 2 2 3 5 5 5 1 Bacterial Ig-like domain (group 2) HpaB_N PF11794.8 ETS74366.1 - 0.0059 16.3 2.6 14 5.2 0.0 4.4 3 2 2 5 5 5 1 4-hydroxyphenylacetate 3-hydroxylase N terminal SpoVS PF04232.12 ETS74366.1 - 0.014 15.1 20.2 5.9 6.7 0.6 5.0 2 2 3 5 5 5 0 Stage V sporulation protein S (SpoVS) DUF3659 PF12396.8 ETS74366.1 - 0.041 13.8 0.2 5.4 7.0 0.0 3.6 4 1 1 5 5 5 0 Protein of unknown function (DUF3659) Bombolitin PF08096.11 ETS74366.1 - 0.13 12.6 2.1 6.6 7.2 0.1 3.8 4 0 0 4 4 4 0 Bombolitin family IATP PF04568.12 ETS74366.1 - 0.19 12.2 8.0 6.5 7.2 0.3 3.6 1 1 4 5 5 5 0 Mitochondrial ATPase inhibitor, IATP TetR_N PF00440.23 ETS74366.1 - 2.2 8.1 9.7 6.3 6.7 0.2 4.2 4 0 0 4 4 4 0 Bacterial regulatory proteins, tetR family Collagen PF01391.18 ETS74367.1 - 5.4e-05 22.9 1.8 8.6e-05 22.2 1.8 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) GFO_IDH_MocA PF01408.22 ETS74367.1 - 0.00075 20.3 0.0 0.0015 19.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AAA PF00004.29 ETS74368.1 - 1.3e-41 142.1 0.0 1.2e-14 54.9 0.0 6.3 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 ETS74368.1 - 7.6e-41 139.9 0.5 4.9e-40 137.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 ETS74368.1 - 8.1e-27 94.6 31.6 3.7e-24 85.9 0.0 6.4 6 0 0 6 6 5 2 AAA domain AAA_30 PF13604.6 ETS74368.1 - 6.9e-21 74.8 1.8 0.00076 19.2 0.0 6.4 6 0 0 6 6 6 5 AAA domain AAA_19 PF13245.6 ETS74368.1 - 2.6e-19 70.0 0.1 2.2e-08 34.6 0.0 6.4 5 1 0 5 5 5 2 AAA domain AAA_lid_6 PF17866.1 ETS74368.1 - 7.7e-17 61.2 6.2 4.1e-08 33.3 0.7 3.0 2 0 0 2 2 2 2 AAA lid domain AAA_5 PF07728.14 ETS74368.1 - 2.7e-11 43.6 1.4 0.11 12.5 0.0 5.9 6 0 0 6 6 5 3 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ETS74368.1 - 4.5e-09 36.0 0.1 0.039 13.3 0.0 5.0 4 1 0 5 5 5 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 ETS74368.1 - 1.2e-08 34.9 0.0 0.55 10.0 0.0 4.5 4 0 0 4 4 4 3 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ETS74368.1 - 1.3e-07 32.2 0.3 2.2 8.6 0.0 5.5 4 1 0 4 4 4 2 AAA ATPase domain AAA_18 PF13238.6 ETS74368.1 - 4.1e-07 30.6 2.2 3.7 8.1 0.0 5.3 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 ETS74368.1 - 6.1e-07 29.8 18.8 0.53 10.6 0.1 8.3 7 3 1 8 8 6 3 AAA domain Torsin PF06309.11 ETS74368.1 - 9.6e-07 28.9 0.0 6.6 6.8 0.0 4.6 4 0 0 4 4 4 1 Torsin IstB_IS21 PF01695.17 ETS74368.1 - 2.8e-06 27.2 0.0 5.7 6.6 0.0 4.8 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.22 ETS74368.1 - 3.1e-06 27.5 4.1 1.9 8.9 0.0 5.4 5 0 0 5 5 5 2 RNA helicase AAA_7 PF12775.7 ETS74368.1 - 8.5e-05 22.1 0.9 5.3 6.5 0.0 4.4 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_33 PF13671.6 ETS74368.1 - 0.0002 21.6 10.7 1.9 8.6 0.1 5.9 5 0 0 5 5 5 2 AAA domain AAA_24 PF13479.6 ETS74368.1 - 0.0013 18.5 12.3 0.46 10.2 0.1 5.5 5 0 0 5 5 5 1 AAA domain NTPase_1 PF03266.15 ETS74368.1 - 0.029 14.3 4.3 20 5.0 0.1 4.7 5 0 0 5 5 5 0 NTPase AAA_6 PF12774.7 ETS74368.1 - 0.1 11.5 1.9 3.2 6.7 0.0 3.3 4 0 0 4 4 4 0 Hydrolytic ATP binding site of dynein motor region SRP54 PF00448.22 ETS74368.1 - 0.11 12.1 4.8 0.6 9.7 0.0 4.1 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain DUF2075 PF09848.9 ETS74368.1 - 0.19 10.9 0.0 0.19 10.9 0.0 7.3 6 2 1 7 7 6 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 ETS74368.1 - 0.29 11.6 18.8 0.41 11.1 0.0 6.1 6 0 0 6 6 5 0 AAA domain AAA_28 PF13521.6 ETS74368.1 - 0.3 11.3 14.2 1.4 9.2 0.0 5.2 5 0 0 5 5 4 0 AAA domain Helicase_RecD PF05127.14 ETS74368.1 - 9.7 6.0 9.0 6.1 6.7 0.0 4.2 3 1 1 4 4 2 0 Helicase SH3_2 PF07653.17 ETS74369.1 - 0.11 12.2 0.6 3 7.6 0.1 2.6 3 0 0 3 3 3 0 Variant SH3 domain MFS_1 PF07690.16 ETS74370.1 - 1.1e-33 116.6 53.4 7.7e-21 74.4 18.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS74370.1 - 7.2e-06 25.1 38.9 0.00019 20.4 17.5 2.9 2 2 0 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.18 ETS74371.1 - 2.1e-12 46.7 0.3 5.4e-12 45.3 0.1 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS74372.1 - 6.3e-09 35.8 11.6 1e-08 35.2 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dodecin PF07311.12 ETS74374.1 - 0.078 13.2 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Dodecin MFS_1 PF07690.16 ETS74375.1 - 3.6e-30 105.1 49.1 7.2e-27 94.2 41.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ETS74375.1 - 1.6e-05 24.4 25.0 2.6e-05 23.7 25.0 1.3 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 ETS74376.1 - 2.5e-32 112.2 27.0 2.5e-32 112.2 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS74376.1 - 3.9e-12 45.8 9.2 3.9e-12 45.8 9.2 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ETS74376.1 - 1.2e-07 30.5 1.9 1.9e-07 29.9 1.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Bestrophin PF01062.21 ETS74378.1 - 1.2e-33 116.8 0.1 1.8e-33 116.2 0.1 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel TraQ PF09679.10 ETS74379.1 - 0.17 11.9 0.1 0.67 9.9 0.1 2.0 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) p450 PF00067.22 ETS74380.1 - 1.2e-13 50.6 0.2 3.1e-13 49.3 0.2 1.6 1 1 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.8 ETS74381.1 - 8.5e-97 324.8 0.0 9.9e-97 324.6 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Arylsulfotran_2 PF14269.6 ETS74382.1 - 1.4e-60 205.2 2.5 2e-60 204.7 2.5 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 ETS74382.1 - 2.3e-14 53.1 1.5 9.3e-13 47.8 1.6 2.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.6 ETS74382.1 - 0.0002 21.0 0.2 0.15 11.6 0.0 3.4 2 1 1 3 3 3 2 PQQ-like domain Glyco_hydro_3_C PF01915.22 ETS74383.1 - 3.9e-50 170.6 0.0 6.5e-50 169.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS74383.1 - 1.4e-41 142.9 0.0 2.4e-41 142.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS74383.1 - 5.9e-23 80.8 2.4 1.1e-22 79.9 0.5 2.3 2 0 0 2 2 2 1 Fibronectin type III-like domain FAD_binding_4 PF01565.23 ETS74384.1 - 2.6e-19 69.4 0.2 4.4e-19 68.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain TRI12 PF06609.13 ETS74385.1 - 9.2e-24 83.8 23.3 1.2e-23 83.4 23.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ETS74385.1 - 1.2e-21 77.1 49.0 1.2e-21 77.1 49.0 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Peptidase_S15 PF02129.18 ETS74386.1 - 8.7e-40 137.0 0.2 7.5e-38 130.7 0.1 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ETS74386.1 - 1.6e-26 93.7 0.0 3.7e-26 92.5 0.0 1.7 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 ETS74386.1 - 0.0024 17.2 0.0 0.0064 15.8 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 ETS74386.1 - 0.0064 15.2 0.0 1 8.0 0.0 2.4 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) CSD2 PF17876.1 ETS74386.1 - 0.17 12.1 0.3 0.76 10.0 0.0 2.2 3 0 0 3 3 3 0 Cold shock domain ABC_tran PF00005.27 ETS74387.1 - 1.3e-40 139.1 0.0 3.6e-22 79.3 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS74387.1 - 1.1e-26 94.1 29.4 9.2e-21 74.7 0.9 3.4 2 1 2 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 ETS74387.1 - 7.3e-14 51.7 4.4 5e-05 22.8 0.6 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETS74387.1 - 1.9e-10 41.1 2.2 0.073 12.9 0.0 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ETS74387.1 - 3.4e-07 30.6 0.3 0.019 15.3 0.2 2.8 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ETS74387.1 - 2.2e-06 27.9 0.1 0.089 12.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 ETS74387.1 - 1.4e-05 24.7 0.5 0.26 11.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_19 PF13245.6 ETS74387.1 - 2.8e-05 24.5 1.0 0.0045 17.3 0.2 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 ETS74387.1 - 0.0001 22.0 0.8 0.13 11.8 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 ETS74387.1 - 0.00012 22.1 0.3 0.047 13.8 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 ETS74387.1 - 0.00051 19.6 0.1 0.64 9.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_23 PF13476.6 ETS74387.1 - 0.00082 19.9 0.4 1.6 9.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ETS74387.1 - 0.0019 18.6 0.2 0.4 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 ETS74387.1 - 0.0019 18.6 0.1 2.1 8.8 0.0 3.1 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 ETS74387.1 - 0.0025 18.4 0.0 0.4 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ETS74387.1 - 0.0042 16.8 0.1 0.29 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 ETS74387.1 - 0.0046 16.1 1.1 0.34 9.9 0.1 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_15 PF13175.6 ETS74387.1 - 0.0085 15.8 0.2 1.5 8.5 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 ETS74387.1 - 0.0087 16.0 0.0 1.2 9.0 0.0 2.6 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 ETS74387.1 - 0.011 15.1 0.6 0.32 10.3 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 ETS74387.1 - 0.016 15.3 0.1 0.032 14.3 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 ETS74387.1 - 0.033 14.1 0.2 2.7 7.9 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase MobB PF03205.14 ETS74387.1 - 0.043 13.7 0.4 6.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 ETS74387.1 - 0.05 13.4 0.0 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 ETS74387.1 - 0.05 13.6 0.1 2 8.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain ABC_ATPase PF09818.9 ETS74387.1 - 0.08 11.7 0.4 0.68 8.7 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class TsaE PF02367.17 ETS74387.1 - 0.11 12.5 0.1 7.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 ETS74387.1 - 0.17 12.1 0.1 23 5.2 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 ETS74387.1 - 0.18 11.1 0.1 19 4.5 0.0 2.6 3 0 0 3 3 2 0 Zeta toxin Dynamin_N PF00350.23 ETS74387.1 - 0.19 11.8 0.9 4.9 7.2 0.3 2.4 2 0 0 2 2 2 0 Dynamin family PRK PF00485.18 ETS74387.1 - 0.43 10.3 1.4 0.6 9.8 0.2 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SbcCD_C PF13558.6 ETS74387.1 - 0.44 10.8 2.2 3.1 8.1 0.2 3.3 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit TrbC PF04956.13 ETS74387.1 - 0.81 9.9 8.9 0.93 9.7 0.6 3.5 2 0 0 2 2 2 0 TrbC/VIRB2 family NACHT PF05729.12 ETS74387.1 - 3.4 7.6 4.7 50 3.7 0.0 3.5 4 0 0 4 4 4 0 NACHT domain RTA1 PF04479.13 ETS74388.1 - 2.3e-64 216.8 6.2 2.3e-64 216.8 6.2 1.8 1 1 1 2 2 2 1 RTA1 like protein LHC PF00556.20 ETS74388.1 - 0.082 13.1 0.5 0.082 13.1 0.5 2.9 3 0 0 3 3 3 0 Antenna complex alpha/beta subunit p450 PF00067.22 ETS74389.1 - 1.4e-74 251.6 0.0 1.6e-74 251.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peroxidase_2 PF01328.17 ETS74390.1 - 1e-53 182.7 0.3 1.3e-53 182.3 0.3 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DIX PF00778.17 ETS74390.1 - 0.14 12.0 0.0 0.55 10.1 0.0 1.9 2 0 0 2 2 2 0 DIX domain RCR PF12273.8 ETS74391.1 - 0.0042 17.7 0.1 0.0084 16.8 0.0 1.5 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red ATP-synt_A PF00119.20 ETS74391.1 - 0.042 13.8 2.7 0.072 13.0 2.2 1.5 2 0 0 2 2 2 0 ATP synthase A chain DUF2070 PF09843.9 ETS74391.1 - 0.057 11.7 0.8 0.072 11.4 0.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Fungal_trans_2 PF11951.8 ETS74392.1 - 5.6e-07 28.7 0.1 9.9e-07 27.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GSDH PF07995.11 ETS74394.1 - 3.8e-06 26.4 0.0 5.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase RCC1_2 PF13540.6 ETS74394.1 - 0.0066 16.2 1.1 6.1 6.8 0.1 3.7 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat PTR2 PF00854.21 ETS74395.1 - 6.3e-57 193.2 4.0 6.3e-57 193.2 4.0 1.6 1 1 0 1 1 1 1 POT family DUF4311 PF14188.6 ETS74395.1 - 0.061 13.1 9.0 0.27 11.0 3.8 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4311) Phage_holin_3_6 PF07332.11 ETS74395.1 - 0.086 12.9 0.3 0.086 12.9 0.3 3.6 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Amidohydro_1 PF01979.20 ETS74396.1 - 3.1e-22 79.4 0.0 1e-21 77.7 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS74396.1 - 1.8e-12 47.5 0.0 2.2e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.20 ETS74396.1 - 0.0055 17.0 0.0 0.016 15.5 0.1 1.8 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Asp PF00026.23 ETS74397.1 - 7.7e-41 140.5 0.1 9.7e-41 140.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 ETS74397.1 - 0.0018 18.0 0.1 0.0096 15.7 0.0 1.9 1 1 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 ETS74397.1 - 0.018 15.3 0.1 0.079 13.2 0.1 2.0 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal SesA PF17107.5 ETS74398.1 - 0.017 15.3 1.3 0.33 11.2 0.1 2.6 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases FF PF01846.19 ETS74399.1 - 1.2e-12 47.7 11.8 1.3e-12 47.6 0.9 3.5 3 0 0 3 3 3 1 FF domain WW PF00397.26 ETS74399.1 - 6.7e-09 35.7 3.2 6.7e-09 35.7 3.2 2.3 2 0 0 2 2 2 1 WW domain Di19_C PF14571.6 ETS74399.1 - 4 8.0 6.6 0.82 10.2 0.3 2.7 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal DLH PF01738.18 ETS74400.1 - 1.2e-25 90.3 0.0 1.4e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF953 PF06110.11 ETS74403.1 - 5e-20 71.3 0.1 6.1e-20 71.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 ETS74403.1 - 0.00078 19.2 0.1 0.0013 18.5 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin PAP2 PF01569.21 ETS74404.1 - 5.8e-27 94.1 2.1 1.4e-26 92.8 0.4 2.2 1 1 1 2 2 2 1 PAP2 superfamily YibE_F PF07907.11 ETS74404.1 - 0.0026 17.3 1.0 0.0053 16.3 1.0 1.4 1 0 0 1 1 1 1 YibE/F-like protein SNARE_assoc PF09335.11 ETS74404.1 - 0.0066 16.9 2.3 0.28 11.7 2.2 2.4 2 0 0 2 2 2 1 SNARE associated Golgi protein HisKA_7TM PF16927.5 ETS74404.1 - 0.18 11.8 7.1 0.13 12.2 5.0 1.7 2 0 0 2 2 2 0 N-terminal 7TM region of histidine kinase AC_N PF16214.5 ETS74404.1 - 0.26 10.4 0.2 0.43 9.6 0.2 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Dynamin_N PF00350.23 ETS74405.1 - 4.3e-21 75.7 0.0 3.9e-20 72.6 0.0 2.6 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 ETS74405.1 - 2e-15 56.8 0.0 6.3e-09 35.5 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 ETS74405.1 - 0.0032 17.6 2.3 0.004 17.3 0.1 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain EloA-BP1 PF15870.5 ETS74405.1 - 0.018 15.3 1.2 0.21 11.9 0.1 2.7 3 0 0 3 3 3 0 ElonginA binding-protein 1 ABC_tran PF00005.27 ETS74405.1 - 0.019 15.5 0.0 0.11 13.0 0.0 2.3 2 0 0 2 2 2 0 ABC transporter IIGP PF05049.13 ETS74405.1 - 0.1 11.6 0.0 0.31 10.0 0.0 1.8 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 ETS74405.1 - 0.12 12.5 0.0 2.6 8.1 0.0 2.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase Sugar_tr PF00083.24 ETS74406.1 - 1.9e-83 280.9 20.7 2.1e-83 280.7 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS74406.1 - 1.3e-28 100.0 19.3 1.8e-28 99.5 19.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS74406.1 - 0.00012 20.7 5.4 0.00032 19.3 2.0 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 ETS74406.1 - 0.0004 19.3 9.1 0.0014 17.6 2.4 2.2 2 0 0 2 2 2 2 POT family YtpI PF14007.6 ETS74406.1 - 0.2 11.8 2.1 0.38 10.9 0.5 2.3 2 0 0 2 2 2 0 YtpI-like protein MG2 PF01835.19 ETS74407.1 - 0.015 15.7 0.0 0.31 11.5 0.0 2.7 2 1 0 2 2 2 0 MG2 domain ThrE PF06738.12 ETS74407.1 - 6 6.2 11.9 0.16 11.3 2.4 2.2 1 1 0 2 2 2 0 Putative threonine/serine exporter p450 PF00067.22 ETS74408.1 - 7.3e-29 100.8 0.0 9.8e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peroxidase_2 PF01328.17 ETS74409.1 - 7.6e-54 183.1 0.0 1e-53 182.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DUF4863 PF16155.5 ETS74410.1 - 2.4e-70 235.3 0.0 2.8e-70 235.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4863) Phosphoesterase PF04185.14 ETS74411.1 - 8.2e-37 127.2 0.3 1.2e-35 123.4 0.3 2.2 1 1 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.23 ETS74411.1 - 0.021 14.3 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Sulfatase adh_short_C2 PF13561.6 ETS74412.1 - 4.4e-51 173.7 0.0 5.1e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS74412.1 - 8.6e-43 146.1 0.0 1.1e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS74412.1 - 4.2e-08 33.3 0.0 6e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS74412.1 - 0.045 13.2 0.0 0.43 10.0 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 ETS74412.1 - 0.047 13.0 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KdpD PF02702.17 ETS74412.1 - 0.093 12.2 0.0 0.21 11.0 0.0 1.5 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain adh_short PF00106.25 ETS74413.1 - 2.6e-25 89.0 0.1 5e-21 75.0 0.0 2.4 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS74413.1 - 1.7e-10 40.9 0.2 1.6e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS74413.1 - 3.4e-08 33.6 0.1 5.3e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Peptidase_M19 PF01244.21 ETS74414.1 - 4.1e-67 226.6 0.0 5.1e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) MFS_1 PF07690.16 ETS74415.1 - 1.6e-31 109.5 25.3 1.6e-31 109.5 25.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily VCBS PF13517.6 ETS74416.1 - 1.8e-14 54.1 12.2 5.6e-05 23.6 3.4 3.9 3 1 1 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 ETS74416.1 - 7.6e-12 45.1 20.6 0.0061 16.7 0.9 4.7 4 0 0 4 4 4 4 FG-GAP repeat TcdB_toxin_midN PF12256.8 ETS74416.1 - 7.2e-06 25.5 7.0 1.5 8.1 0.3 4.2 2 1 2 4 4 4 4 Insecticide toxin TcdB middle/N-terminal region PliI PF16743.5 ETS74416.1 - 4.5e-05 23.2 0.4 0.058 13.1 0.3 3.5 3 1 1 4 4 4 2 Periplasmic lysozyme inhibitor of I-type lysozyme Itfg2 PF15907.5 ETS74416.1 - 0.0053 15.9 0.3 1.2 8.1 0.0 3.0 3 1 0 3 3 3 2 Integrin-alpha FG-GAP repeat-containing protein 2 EF-hand_5 PF13202.6 ETS74416.1 - 0.033 13.7 14.9 3.9 7.1 0.4 4.3 4 0 0 4 4 4 0 EF hand EF-hand_1 PF00036.32 ETS74416.1 - 0.12 12.0 9.1 3.1 7.6 0.2 4.2 4 0 0 4 4 4 0 EF hand Rcd1 PF04078.13 ETS74417.1 - 8.5e-125 415.2 4.9 1e-124 415.0 4.9 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Opi1 PF08618.10 ETS74417.1 - 0.03 13.6 1.7 0.046 13.0 1.7 1.2 1 0 0 1 1 1 0 Transcription factor Opi1 CcmD PF04995.14 ETS74418.1 - 0.042 13.9 0.3 0.098 12.8 0.3 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) UvrD-helicase PF00580.21 ETS74419.1 - 9.3e-63 212.6 0.6 5.7e-61 206.8 0.6 2.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 ETS74419.1 - 9.9e-63 212.6 0.0 3.8e-62 210.7 0.0 1.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 ETS74419.1 - 4e-30 105.1 0.0 7.6e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 ETS74419.1 - 3.6e-14 52.3 0.0 7.6e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 ETS74419.1 - 2.9e-08 33.7 0.4 0.00012 21.9 0.2 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 ETS74419.1 - 1.3e-05 25.0 0.1 0.24 11.1 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 ETS74419.1 - 0.0017 18.0 0.0 0.017 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 ETS74419.1 - 0.0089 15.8 0.2 0.045 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ETS74419.1 - 0.2 11.9 0.9 8.1 6.7 0.2 3.0 2 1 0 2 2 2 0 AAA domain Amidohydro_1 PF01979.20 ETS74420.1 - 1.5e-11 44.2 0.0 4.6e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS74420.1 - 3.6e-08 33.3 0.0 3.6e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Glyco_hydro_3 PF00933.21 ETS74421.1 - 6e-60 203.3 0.0 8e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 ETS74421.1 - 0.0002 21.6 0.0 0.00093 19.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS74421.1 - 0.051 13.5 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.22 ETS74421.1 - 0.076 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain NDT80_PhoG PF05224.12 ETS74422.1 - 9.9e-35 120.4 0.4 1.1e-33 117.0 0.0 2.4 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Hexokinase_2 PF03727.16 ETS74423.1 - 3.5e-54 183.8 0.0 5.3e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ETS74423.1 - 1.2e-43 149.3 0.0 1.9e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF2397 PF09660.10 ETS74423.1 - 0.082 11.8 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) Glucosamine_iso PF01182.20 ETS74424.1 - 4e-20 72.7 0.0 6.3e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_31 PF01055.26 ETS74425.1 - 4.2e-105 352.5 0.2 5.2e-105 352.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 ETS74425.1 - 1e-14 54.6 0.0 3.1e-14 53.1 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like DUF2396 PF09654.10 ETS74425.1 - 0.058 13.5 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) Glyco_hydro_3 PF00933.21 ETS74426.1 - 1.7e-57 195.2 0.0 2.3e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 ETS74426.1 - 7.2e-50 169.8 0.0 1.4e-49 168.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ETS74426.1 - 2.8e-23 81.8 0.6 1.3e-22 79.7 0.2 2.4 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.13 ETS74426.1 - 0.007 15.5 0.1 0.013 14.6 0.1 1.4 1 0 0 1 1 1 1 Putative sugar-binding domain DUF4841 PF16129.5 ETS74426.1 - 0.032 14.5 0.1 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4841) TBP-binding PF09247.11 ETS74426.1 - 0.095 13.0 0.0 6 7.2 0.1 2.4 2 0 0 2 2 2 0 TATA box-binding protein binding Big_3_5 PF16640.5 ETS74426.1 - 0.38 11.0 4.8 0.65 10.2 0.2 2.9 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) HET PF06985.11 ETS74427.1 - 1.1e-29 103.7 0.0 2.3e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aminotran_1_2 PF00155.21 ETS74428.1 - 1.5e-10 40.8 0.0 1.2e-09 37.8 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ETS74428.1 - 0.0034 16.2 0.0 0.047 12.5 0.0 2.1 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase VHS PF00790.19 ETS74429.1 - 5.5e-35 120.3 0.0 1.3e-34 119.1 0.0 1.6 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 ETS74429.1 - 3.1e-15 55.5 0.3 7.3e-15 54.3 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 ETS74429.1 - 1.3e-14 53.8 0.1 2.9e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ETS74429.1 - 6.7e-13 48.1 0.0 1.7e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 ETS74429.1 - 2.2e-10 40.7 2.4 4.7e-10 39.6 1.7 2.0 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 ETS74429.1 - 0.017 15.0 5.8 0.045 13.7 5.8 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif CemA PF03040.14 ETS74429.1 - 0.54 10.2 1.8 5.1 7.0 0.1 2.2 2 0 0 2 2 2 0 CemA family ATG13 PF10033.9 ETS74430.1 - 5.9e-66 222.6 0.0 8.7e-66 222.0 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 Glyco_hydro_125 PF06824.11 ETS74431.1 - 2.7e-173 576.6 0.1 3.1e-173 576.4 0.1 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Glyco_hydro_92 PF07971.12 ETS74432.1 - 3.7e-145 484.4 0.0 4.4e-145 484.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 ETS74432.1 - 5.1e-64 216.4 0.2 7.7e-64 215.8 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Cyt-b5 PF00173.28 ETS74433.1 - 3.1e-13 49.7 0.0 1.3e-12 47.6 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.18 ETS74433.1 - 1.7e-11 43.5 0.0 7.8e-11 41.4 0.0 1.9 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase NAD_binding_1 PF00175.21 ETS74433.1 - 9.4e-10 39.1 0.0 2.2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 ETS74433.1 - 7.6e-09 35.5 0.0 7.9e-08 32.1 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain Zn_clus PF00172.18 ETS74434.1 - 5.3e-10 39.3 11.9 8.2e-10 38.6 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM222A PF15258.6 ETS74434.1 - 8.2e-05 21.9 27.3 8.2e-05 21.9 27.3 2.7 1 1 1 2 2 2 1 Protein family of FAM222A Zds_C PF08632.10 ETS74436.1 - 2.3e-29 100.9 0.6 5.2e-29 99.8 0.6 1.6 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Bac_rhamnosid_C PF17390.2 ETS74437.1 - 3.9e-08 33.0 0.0 1.1e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 ETS74437.1 - 1.8e-07 30.8 0.2 2.2e-06 27.2 0.3 2.1 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain SET PF00856.28 ETS74438.1 - 0.0047 17.3 0.0 7.7 6.9 0.0 2.9 2 1 0 2 2 2 2 SET domain RPS31 PF17067.5 ETS74439.1 - 0.14 12.3 0.3 0.24 11.6 0.3 1.3 1 0 0 1 1 1 0 Ribosomal protein S31e Cu-oxidase_3 PF07732.15 ETS74440.1 - 7.1e-40 135.7 6.1 1.2e-39 135.0 2.3 3.0 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ETS74440.1 - 8.5e-40 135.7 13.1 1.6e-39 134.7 1.2 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 ETS74440.1 - 1.5e-34 119.4 1.2 7e-34 117.2 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase Glyco_hydro_43 PF04616.14 ETS74441.1 - 3.3e-51 174.3 5.8 4.9e-51 173.7 5.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ETS74441.1 - 1.5e-11 44.4 0.0 2.5e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain SNF2_N PF00176.23 ETS74442.1 - 4.6e-66 222.9 6.4 1.6e-61 208.0 1.8 3.2 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS74442.1 - 1.7e-16 60.5 0.0 6.6e-16 58.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ETS74442.1 - 4.3e-06 26.6 0.0 1.2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ETS74442.1 - 5.8e-06 26.4 0.0 1.9e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DZR PF12773.7 ETS74442.1 - 0.016 15.2 0.1 0.034 14.2 0.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon RPN2_C PF18004.1 ETS74442.1 - 0.026 14.4 0.1 0.026 14.4 0.1 3.9 2 1 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain zf-AD PF07776.15 ETS74442.1 - 0.12 12.6 0.1 0.37 11.1 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) DUF4428 PF14471.6 ETS74442.1 - 0.73 9.8 2.4 1.7 8.7 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Ran-binding PF05508.11 ETS74443.1 - 3.9e-85 285.6 0.0 5e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.27 ETS74444.1 - 1.4e-41 142.2 0.0 2.2e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ETS74444.1 - 5.9e-29 100.6 0.0 1.7e-28 99.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ETS74444.1 - 8.7e-09 35.7 2.2 4.9e-08 33.2 0.3 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ETS74444.1 - 0.0014 18.7 0.1 0.0079 16.3 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase PhageP22-tail PF09251.10 ETS74444.1 - 0.73 8.1 5.3 1.1 7.5 5.3 1.1 1 0 0 1 1 1 0 Salmonella phage P22 tail-spike PEPCK_ATP PF01293.20 ETS74445.1 - 6.6e-216 717.4 0.0 7.8e-216 717.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 ETS74445.1 - 0.16 12.4 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 ETS74445.1 - 0.19 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain 2-Hacid_dh_C PF02826.19 ETS74446.1 - 4.2e-38 130.5 0.0 6e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS74446.1 - 1.2e-17 63.9 0.1 1.5e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 ETS74446.1 - 2.3e-05 24.9 0.1 6e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ETS74446.1 - 0.0006 20.0 0.2 0.001 19.3 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 ETS74446.1 - 0.001 19.2 0.8 0.0029 17.7 0.8 1.8 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 ETS74446.1 - 0.003 17.1 0.0 0.0058 16.2 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 ETS74446.1 - 0.0035 16.7 1.0 0.0035 16.7 1.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ANF_receptor PF01094.28 ETS74446.1 - 0.0091 15.1 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Arch_flagellin PF01917.16 ETS74446.1 - 0.033 14.4 0.0 0.31 11.2 0.0 2.1 2 0 0 2 2 2 0 Archaebacterial flagellin XdhC_C PF13478.6 ETS74446.1 - 0.088 13.3 0.0 0.27 11.8 0.0 1.9 1 1 1 2 2 2 0 XdhC Rossmann domain 3HCDH_N PF02737.18 ETS74446.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UCH_1 PF13423.6 ETS74447.1 - 3.4e-85 286.5 1.3 3.9e-85 286.3 0.3 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 ETS74447.1 - 3.9e-21 76.3 0.0 1.1e-20 74.8 0.0 1.9 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 ETS74447.1 - 4.5e-09 36.2 0.6 1.2e-06 28.3 0.6 3.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40_like PF17005.5 ETS74447.1 - 0.092 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain Tnp_zf-ribbon_2 PF13842.6 ETS74447.1 - 1.6 9.6 3.9 58 4.6 0.1 3.4 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon SPX PF03105.19 ETS74448.1 - 0.24 11.3 12.2 0.32 10.9 12.2 1.2 1 0 0 1 1 1 0 SPX domain HNF-1_N PF04814.13 ETS74448.1 - 0.24 12.0 8.6 0.065 13.9 3.8 2.1 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus DUF1180 PF06679.12 ETS74448.1 - 2.3 8.6 7.1 0.55 10.6 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Methyltransf_23 PF13489.6 ETS74449.1 - 1.2e-17 64.3 0.0 2.5e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS74449.1 - 9.2e-07 29.5 0.0 0.12 13.1 0.0 3.3 2 1 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 ETS74449.1 - 6.3e-06 26.8 0.0 0.00041 20.9 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS74449.1 - 8e-06 25.4 0.0 0.0044 16.4 0.0 2.3 2 1 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ETS74449.1 - 4.5e-05 24.1 0.0 0.00022 21.9 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS74449.1 - 0.003 17.4 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain NmrA PF05368.13 ETS74450.1 - 1.3e-13 51.0 0.0 1.7e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS74450.1 - 4.9e-09 36.3 0.0 7.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS74450.1 - 0.00061 19.3 0.0 0.00092 18.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2826 PF11442.8 ETS74450.1 - 0.088 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) DUF2811 PF10929.8 ETS74450.1 - 0.11 12.8 0.6 0.55 10.6 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2811) AATase PF07247.12 ETS74451.1 - 3.2e-17 62.3 0.1 4e-16 58.7 0.0 2.3 2 1 0 2 2 2 1 Alcohol acetyltransferase Condensation PF00668.20 ETS74451.1 - 6.3e-06 25.1 0.8 9e-06 24.6 0.4 1.4 2 0 0 2 2 2 1 Condensation domain WES_acyltransf PF03007.16 ETS74451.1 - 0.00086 19.1 0.2 0.0013 18.5 0.2 1.4 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain T2SSE_N PF05157.15 ETS74451.1 - 0.051 13.9 0.0 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein E, N-terminal domain FMO-like PF00743.19 ETS74452.1 - 8.9e-67 225.7 0.0 1.5e-66 224.9 0.0 1.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ETS74452.1 - 2.1e-12 46.9 0.0 1.3e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS74452.1 - 1.5e-09 37.6 0.0 2.3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS74452.1 - 2.2e-09 37.0 0.2 3.6e-07 29.6 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ETS74452.1 - 1.3e-08 34.9 0.0 4.6e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS74452.1 - 1.9e-05 24.7 0.0 0.00021 21.3 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 ETS74452.1 - 3e-05 24.5 0.1 0.0054 17.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS74452.1 - 0.00026 20.3 0.1 0.0013 18.0 0.0 2.0 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 ETS74452.1 - 0.00064 19.0 0.1 0.0018 17.6 0.0 1.7 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 ETS74452.1 - 0.0007 19.3 0.1 0.16 11.5 0.0 2.7 2 1 0 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 ETS74452.1 - 0.0025 17.9 0.0 0.62 10.1 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 ETS74452.1 - 0.0077 16.7 0.0 3.1 8.3 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 ETS74452.1 - 0.009 15.4 0.1 0.58 9.5 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 ETS74452.1 - 0.022 13.5 0.1 0.063 12.0 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Glu_dehyd_C PF16912.5 ETS74452.1 - 0.06 12.8 0.1 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus NAD_binding_2 PF03446.15 ETS74452.1 - 0.061 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pedibin PF08182.11 ETS74452.1 - 0.067 13.0 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Pedibin/Hym-346 family IlvN PF07991.12 ETS74452.1 - 0.11 12.1 0.0 0.45 10.1 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 ETS74452.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GFA PF04828.14 ETS74453.1 - 5.3e-15 55.5 1.9 3e-07 30.7 2.1 2.8 4 0 0 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 ETS74453.1 - 7 6.9 13.8 33 4.7 0.1 3.6 3 1 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like DUF4271 PF14093.6 ETS74454.1 - 0.019 14.9 7.8 0.057 13.3 8.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) Yip1 PF04893.17 ETS74454.1 - 2.2 7.9 14.7 3.7 7.2 10.4 2.2 1 1 1 2 2 2 0 Yip1 domain 4HBT PF03061.22 ETS74456.1 - 1.2e-13 51.2 0.1 1.8e-13 50.6 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 ETS74456.1 - 0.038 14.1 0.0 0.051 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) DbpA PF03880.15 ETS74457.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 DbpA RNA binding domain DUF1761 PF08570.10 ETS74458.1 - 0.045 14.0 1.5 0.098 12.9 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) DUF805 PF05656.14 ETS74458.1 - 0.78 10.2 4.5 11 6.5 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Peroxidase_2 PF01328.17 ETS74459.1 - 1e-42 146.8 0.3 1.3e-42 146.4 0.3 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DIX PF00778.17 ETS74459.1 - 0.0026 17.6 0.0 0.0068 16.2 0.0 1.7 2 0 0 2 2 2 1 DIX domain Glyco_hydro_3_C PF01915.22 ETS74460.1 - 7.4e-45 153.4 0.0 1.4e-44 152.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS74460.1 - 8e-37 127.3 0.0 1.8e-36 126.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS74460.1 - 1.7e-18 66.4 0.0 3.4e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Myb_DNA-binding PF00249.31 ETS74461.1 - 1.6e-06 28.2 0.0 2.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 ETS74461.1 - 0.00013 22.3 0.0 0.00027 21.3 0.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ETS74461.1 - 0.0054 16.9 0.0 0.0087 16.3 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Med3 PF11593.8 ETS74461.1 - 0.063 12.5 10.2 0.089 12.0 10.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MADF_DNA_bdg PF10545.9 ETS74461.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like ABC2_membrane PF01061.24 ETS74462.1 - 3.7e-74 248.7 60.1 1.3e-40 139.0 20.1 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ETS74462.1 - 2.4e-37 128.5 0.3 2.3e-18 67.0 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 ETS74462.1 - 1.4e-26 92.2 10.5 4.4e-24 84.2 0.0 3.9 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 ETS74462.1 - 9.1e-16 58.3 3.8 1.4e-15 57.6 0.0 3.1 3 0 0 3 3 2 1 ABC-transporter N-terminal AAA_33 PF13671.6 ETS74462.1 - 3.7e-06 27.1 1.2 0.051 13.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 ETS74462.1 - 2e-05 25.2 0.0 0.042 14.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 ETS74462.1 - 2.5e-05 24.2 0.0 0.22 11.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ETS74462.1 - 3.2e-05 24.4 0.2 0.16 12.3 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.6 ETS74462.1 - 5.2e-05 23.7 0.5 0.14 12.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 ETS74462.1 - 6.9e-05 22.8 0.0 0.0012 18.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 ETS74462.1 - 0.00011 21.9 0.4 0.016 15.0 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ETS74462.1 - 0.00027 20.5 0.2 0.06 12.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ETS74462.1 - 0.0012 19.2 0.0 2.1 8.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 ETS74462.1 - 0.0025 17.4 1.6 0.22 11.1 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 ETS74462.1 - 0.0035 16.8 0.1 0.33 10.3 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 ETS74462.1 - 0.018 15.0 1.3 3.8 7.4 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 ETS74462.1 - 0.019 14.7 0.7 12 5.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain DnaB_C PF03796.15 ETS74462.1 - 0.02 14.2 0.1 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RNA_helicase PF00910.22 ETS74462.1 - 0.023 15.1 1.1 10 6.6 0.0 4.1 4 0 0 4 4 4 0 RNA helicase AAA_28 PF13521.6 ETS74462.1 - 0.037 14.3 0.7 1.3 9.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA PF00004.29 ETS74462.1 - 0.041 14.3 0.1 22 5.5 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 ETS74462.1 - 0.042 14.2 0.2 2.6 8.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 ETS74462.1 - 0.11 11.7 0.4 13 5.0 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin ABC2_membrane_3 PF12698.7 ETS74462.1 - 0.14 11.2 45.0 0.012 14.8 13.3 2.6 2 0 0 2 2 2 0 ABC-2 family transporter protein PduV-EutP PF10662.9 ETS74462.1 - 0.15 11.8 1.2 6.2 6.6 0.1 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 ETS74462.1 - 0.2 11.7 0.5 9.8 6.2 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 ETS74462.1 - 0.22 10.8 0.5 9.4 5.5 0.1 2.6 3 0 0 3 3 2 0 KaiC DUF4655 PF15548.6 ETS74462.1 - 1 8.3 11.8 1.6 7.6 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) Ank_4 PF13637.6 ETS74464.1 - 3.4e-42 142.3 7.4 2.1e-08 34.5 0.0 7.4 3 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS74464.1 - 7.3e-42 141.9 9.7 1.5e-10 41.5 0.2 5.5 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS74464.1 - 1e-26 90.0 7.0 0.00077 19.7 0.0 12.5 12 0 0 12 12 12 4 Ankyrin repeat Ank PF00023.30 ETS74464.1 - 1.6e-26 91.5 21.2 0.0013 19.1 0.0 11.9 12 0 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.6 ETS74464.1 - 1.9e-17 63.1 8.3 0.00011 22.4 0.0 7.5 3 2 4 8 8 8 5 Ankyrin repeats (many copies) NACHT PF05729.12 ETS74464.1 - 6e-08 32.8 0.1 1.3e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 ETS74464.1 - 8.8e-05 21.9 1.4 0.14 11.4 0.4 2.2 1 1 1 2 2 2 2 KAP family P-loop domain AAA_16 PF13191.6 ETS74464.1 - 0.0026 18.2 0.0 0.011 16.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS74464.1 - 0.005 17.1 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ETS74464.1 - 0.0054 17.2 0.0 0.021 15.2 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ETS74464.1 - 0.0071 16.1 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ETS74464.1 - 0.0085 16.4 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 ETS74464.1 - 0.022 14.0 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DAP3 PF10236.9 ETS74464.1 - 0.057 12.6 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_28 PF13521.6 ETS74464.1 - 0.057 13.7 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 ETS74464.1 - 0.06 12.2 0.1 0.1 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.27 ETS74464.1 - 0.067 13.7 0.0 0.66 10.5 0.0 2.3 2 0 0 2 2 2 0 ABC transporter DUF1843 PF08898.10 ETS74464.1 - 0.092 13.3 12.7 1.4 9.5 0.3 5.6 6 1 0 6 6 5 0 Domain of unknown function (DUF1843) NB-ARC PF00931.22 ETS74464.1 - 0.092 11.9 0.0 0.73 9.0 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain rRNA_proc-arch PF13234.6 ETS74464.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 rRNA-processing arch domain DUF2247 PF10004.9 ETS74464.1 - 0.14 11.9 0.7 0.39 10.5 0.7 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) RNA_helicase PF00910.22 ETS74464.1 - 0.18 12.2 0.0 0.51 10.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 ETS74464.1 - 0.19 11.6 0.0 0.66 9.9 0.0 1.9 1 1 0 1 1 1 0 NTPase AAA_11 PF13086.6 ETS74464.1 - 0.21 11.3 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Meth_synt_2 PF01717.18 ETS74466.1 - 4.8e-14 52.4 0.0 2.1e-10 40.4 0.0 2.3 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 ETS74466.1 - 0.16 11.5 0.0 0.52 9.8 0.0 1.9 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain Takusan PF04822.13 ETS74467.1 - 0.035 14.0 0.5 0.063 13.2 0.5 1.4 1 0 0 1 1 1 0 Takusan Catalase PF00199.19 ETS74468.1 - 5.6e-170 565.5 0.0 6.5e-170 565.3 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 ETS74468.1 - 0.022 14.9 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 Catalase-related immune-responsive Oxidored_molyb PF00174.19 ETS74469.1 - 1.3e-47 161.6 0.0 5.4e-46 156.3 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 ETS74469.1 - 1.9e-20 73.3 3.7 3.4e-20 72.5 3.7 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Response_reg PF00072.24 ETS74470.1 - 6.3e-17 61.8 0.0 1.6e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 ETS74470.1 - 6.1e-11 42.8 0.0 1.3e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ETS74470.1 - 3.3e-09 36.7 2.0 1.5e-08 34.6 0.0 2.9 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.6 ETS74470.1 - 0.02 15.2 0.0 0.19 12.0 0.0 2.5 1 1 1 2 2 2 0 GAF domain FleQ PF06490.11 ETS74470.1 - 0.093 13.1 0.0 12 6.3 0.0 2.8 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ Abhydrolase_6 PF12697.7 ETS74471.1 - 1.8e-20 74.5 1.1 2.1e-20 74.3 1.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ETS74471.1 - 2.1e-05 24.4 0.2 3.6e-05 23.6 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 ETS74471.1 - 0.00044 20.4 0.0 0.00089 19.4 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain Hydrolase_4 PF12146.8 ETS74471.1 - 0.00054 19.3 0.0 0.0048 16.2 0.1 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS74471.1 - 0.0023 17.6 0.0 0.0034 17.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 ETS74471.1 - 0.094 12.3 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase PGAP1 PF07819.13 ETS74471.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein GtrA PF04138.14 ETS74472.1 - 0.073 13.3 3.3 1.6 9.0 0.2 2.6 2 0 0 2 2 2 0 GtrA-like protein p450 PF00067.22 ETS74473.1 - 2.8e-40 138.5 0.0 3.8e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 ETS74474.1 - 3.2e-62 210.1 0.8 5e-62 209.5 0.8 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS74474.1 - 6.5e-51 172.6 0.6 1e-50 172.0 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS74474.1 - 5.3e-11 42.8 0.2 7.2e-11 42.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS74474.1 - 0.00026 20.6 0.1 0.00044 19.8 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.22 ETS74474.1 - 0.002 18.1 0.2 0.017 15.1 0.1 2.3 2 0 0 2 2 2 1 PA domain GDP_Man_Dehyd PF16363.5 ETS74474.1 - 0.0098 15.3 0.1 0.017 14.5 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ETS74474.1 - 0.026 13.6 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 ETS74474.1 - 0.084 13.6 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_S8 PF00082.22 ETS74475.1 - 3.6e-30 105.2 22.0 8.5e-30 104.0 22.0 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ETS74475.1 - 6e-09 36.5 0.1 3.5e-08 34.0 0.1 2.1 1 1 0 1 1 1 1 Peptidase inhibitor I9 Fungal_trans_2 PF11951.8 ETS74476.1 - 3.9e-32 111.5 1.8 5.3e-32 111.1 1.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS74476.1 - 1.7e-10 40.8 11.5 2.8e-10 40.1 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep PF00132.24 ETS74477.1 - 3e-15 55.3 14.1 7.8e-11 41.3 6.1 3.3 2 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ETS74477.1 - 2.4e-11 43.2 14.0 9.8e-08 31.6 6.3 3.2 3 0 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 ETS74477.1 - 3.4e-08 33.6 0.1 5.3e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase MFS_1 PF07690.16 ETS74478.1 - 3.9e-20 72.1 51.2 7.9e-16 57.9 34.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS74478.1 - 0.00028 19.6 1.6 0.00028 19.6 1.6 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein APC_N_CC PF16689.5 ETS74479.1 - 0.0031 17.5 1.4 0.1 12.7 0.4 3.4 1 1 1 2 2 2 1 Coiled-coil N-terminus of APC, dimerisation domain GAS PF13851.6 ETS74479.1 - 0.012 15.0 73.9 0.028 13.8 4.0 5.9 2 2 2 5 5 5 0 Growth-arrest specific micro-tubule binding Spermine_synth PF01564.17 ETS74480.1 - 4.9e-07 29.3 0.0 1.8e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 ETS74480.1 - 0.035 14.0 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 ETS74480.1 - 0.11 13.3 0.0 0.23 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 ETS74480.1 - 0.11 13.3 0.0 0.21 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF5523 PF17661.1 ETS74481.1 - 0.0052 16.5 1.2 0.0081 15.9 1.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5523) Apt1 PF10351.9 ETS74481.1 - 0.44 9.4 4.0 0.47 9.3 4.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Rad10 PF03834.14 ETS74484.1 - 4.7e-46 155.5 0.0 6.5e-46 155.0 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 ETS74484.1 - 4e-05 24.1 0.0 9.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain UIM PF02809.20 ETS74484.1 - 0.061 13.3 0.6 0.26 11.3 0.6 2.2 1 0 0 1 1 1 0 Ubiquitin interaction motif Glyco_hydro_47 PF01532.20 ETS74485.1 - 2.4e-143 478.3 0.0 2.8e-143 478.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1295 PF06966.12 ETS74486.1 - 5.3e-39 134.1 0.4 2.6e-37 128.6 0.4 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) GST_N PF02798.20 ETS74486.1 - 0.062 13.7 0.0 0.22 11.9 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain FBPase PF00316.20 ETS74487.1 - 1.3e-71 240.0 0.1 1.7e-71 239.6 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Peptidase_S10 PF00450.22 ETS74488.1 - 5.9e-72 243.4 0.0 1.1e-71 242.5 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase DUF3237 PF11578.8 ETS74490.1 - 1.1e-24 87.0 0.6 2.4e-18 66.4 0.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3237) Acatn PF13000.7 ETS74490.1 - 0.16 10.4 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Acetyl-coenzyme A transporter 1 Sec3_C PF09763.9 ETS74491.1 - 1.6e-235 783.8 5.0 2e-235 783.4 5.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 ETS74491.1 - 1.6e-27 95.4 0.0 3.2e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 ETS74491.1 - 0.00058 20.1 1.1 0.011 16.1 0.0 3.4 4 0 0 4 4 4 1 Sec3 exocyst complex subunit MutS_II PF05188.17 ETS74491.1 - 0.016 15.5 0.0 0.049 13.9 0.0 1.8 1 0 0 1 1 1 0 MutS domain II MIF4G PF02854.19 ETS74491.1 - 1.7 8.2 6.7 6.1 6.4 6.7 1.8 1 1 0 1 1 1 0 MIF4G domain ARID PF01388.21 ETS74492.1 - 2.4e-16 60.2 0.0 6.1e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 ETS74492.1 - 2.6e-05 24.8 0.0 5.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Arm PF00514.23 ETS74492.1 - 0.013 15.6 0.1 1.8 8.7 0.0 2.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat SEN1_N PF12726.7 ETS74492.1 - 0.088 11.0 0.4 0.12 10.5 0.4 1.2 1 0 0 1 1 1 0 SEN1 N terminal Patatin PF01734.22 ETS74494.1 - 7.5e-13 49.1 0.0 5.3e-12 46.3 0.0 2.2 2 0 0 2 2 2 1 Patatin-like phospholipase ABC_tran PF00005.27 ETS74494.1 - 0.0029 18.1 0.0 0.012 16.1 0.0 1.9 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 ETS74494.1 - 0.0045 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 ETS74494.1 - 0.019 15.0 0.0 0.057 13.5 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 ETS74494.1 - 0.023 15.0 0.0 0.068 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain zf-C3HC4_3 PF13920.6 ETS74494.1 - 0.03 14.2 20.2 0.3 11.0 7.5 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zeta_toxin PF06414.12 ETS74494.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin zf-RING_UBOX PF13445.6 ETS74494.1 - 0.2 11.7 9.9 0.78 9.8 9.5 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 ETS74494.1 - 0.32 10.9 19.5 0.1 12.5 6.9 3.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ETS74494.1 - 0.66 10.4 22.9 1.5 9.2 7.5 3.0 2 0 0 2 2 2 0 Ring finger domain ZZ PF00569.17 ETS74494.1 - 3.7 7.5 11.9 0.49 10.2 7.2 2.0 2 0 0 2 2 2 0 Zinc finger, ZZ type zf-RING_5 PF14634.6 ETS74494.1 - 9.5 6.3 22.1 0.072 13.1 6.7 3.0 2 1 0 2 2 2 0 zinc-RING finger domain Atx10homo_assoc PF09759.9 ETS74495.1 - 7.6e-10 38.7 0.0 1.6e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain DUF2628 PF10947.8 ETS74498.1 - 0.038 14.3 0.2 0.056 13.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) VIT1 PF01988.19 ETS74498.1 - 1.9 8.3 7.6 3.2 7.6 7.6 1.2 1 0 0 1 1 1 0 VIT family AMP-binding PF00501.28 ETS74499.1 - 9.4e-71 238.6 0.0 1.3e-70 238.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS74499.1 - 1.9e-05 25.6 0.0 4.1e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cerato-platanin PF07249.12 ETS74500.1 - 0.0015 18.7 0.1 0.0015 18.7 0.1 1.7 2 0 0 2 2 2 1 Cerato-platanin AA_permease_2 PF13520.6 ETS74501.1 - 5.7e-77 259.3 32.1 6.8e-77 259.1 32.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS74501.1 - 9.8e-15 54.1 28.1 1.6e-14 53.4 28.1 1.3 1 0 0 1 1 1 1 Amino acid permease EMP70 PF02990.16 ETS74502.1 - 0.072 11.7 0.1 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 CorA PF01544.18 ETS74502.1 - 0.17 11.2 5.7 0.4 9.9 4.5 2.1 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein SBD_N PF07005.11 ETS74503.1 - 2.4e-63 213.9 0.1 2.4e-63 213.9 0.1 1.8 3 0 0 3 3 3 1 Sugar-binding N-terminal domain NBD_C PF17042.5 ETS74503.1 - 3.2e-44 151.4 0.2 8.1e-44 150.1 0.1 1.7 2 0 0 2 2 2 1 Nucleotide-binding C-terminal domain Fungal_trans PF04082.18 ETS74504.1 - 2.4e-06 26.8 1.3 5.4e-06 25.6 1.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Tup_N PF08581.10 ETS74504.1 - 0.14 12.5 0.6 0.47 10.8 0.6 1.9 1 0 0 1 1 1 0 Tup N-terminal MFS_1 PF07690.16 ETS74505.1 - 1.2e-33 116.5 33.2 1.4e-33 116.3 32.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5090 PF17009.5 ETS74505.1 - 6.7 6.6 9.3 0.07 13.1 0.8 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5090) SAF PF08666.12 ETS74506.1 - 1.2e-07 32.2 0.0 3.3e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 SAF domain NAD_binding_3 PF03447.16 ETS74506.1 - 2.5e-06 28.1 0.2 2.3e-05 25.0 0.2 2.6 3 1 0 3 3 3 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 ETS74506.1 - 3.8e-05 24.5 0.1 9.6e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 ETS74506.1 - 0.0026 17.9 0.9 0.014 15.5 0.9 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.24 ETS74506.1 - 0.043 14.2 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain AgrB PF04647.15 ETS74507.1 - 0.065 12.5 6.0 0.12 11.6 6.0 1.4 1 0 0 1 1 1 0 Accessory gene regulator B AMP-binding PF00501.28 ETS74508.1 - 3.1e-64 217.1 0.0 4e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS74508.1 - 1.6e-10 41.8 0.1 2.9e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RHH_1 PF01402.21 ETS74508.1 - 0.046 13.7 0.6 0.11 12.5 0.6 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Hce2 PF14856.6 ETS74509.1 - 6.2e-15 55.3 0.0 8.1e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Epimerase PF01370.21 ETS74510.1 - 1.1e-17 64.4 0.0 1.5e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS74510.1 - 5.6e-07 28.9 0.2 0.0098 14.9 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 ETS74510.1 - 1.2e-06 28.3 0.2 4.8e-06 26.3 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 ETS74510.1 - 1.5e-06 27.9 0.0 1.3e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ETS74510.1 - 6.2e-06 26.2 0.0 9.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 ETS74510.1 - 9e-05 22.0 0.5 0.00019 21.0 0.5 1.5 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 ETS74510.1 - 0.0089 15.2 0.1 0.074 12.1 0.1 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 ETS74510.1 - 0.033 14.5 0.2 0.069 13.4 0.2 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Rossmann-like PF10727.9 ETS74510.1 - 2.2 8.1 5.3 0.71 9.7 0.1 2.6 4 0 0 4 4 4 0 Rossmann-like domain Zn_clus PF00172.18 ETS74511.1 - 0.0032 17.5 9.4 0.006 16.7 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 ETS74512.1 - 4.4e-88 296.1 18.4 5e-88 295.9 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS74512.1 - 2.8e-29 102.1 41.7 1e-26 93.7 22.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ETS74512.1 - 0.29 9.4 7.2 0.37 9.0 0.2 2.6 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Pex24p PF06398.11 ETS74515.1 - 4e-100 335.3 0.3 5e-100 335.0 0.3 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin VIR_N PF15912.5 ETS74515.1 - 1.5 8.4 4.1 2.6 7.6 4.1 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal PWWP PF00855.17 ETS74516.1 - 6.9e-05 23.2 1.8 0.00014 22.2 0.2 2.4 2 0 0 2 2 2 1 PWWP domain Abhydrolase_1 PF00561.20 ETS74517.1 - 5.8e-13 49.1 0.0 1.8e-12 47.4 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS74517.1 - 3e-08 33.2 0.0 2.2e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS74517.1 - 1.9e-07 32.0 0.0 2.3e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 ETS74517.1 - 8.5e-06 24.7 0.0 1.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.7 ETS74517.1 - 0.16 11.7 0.0 3.7 7.3 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family FAT PF02259.23 ETS74518.1 - 1.1e-126 422.8 7.3 2.1e-126 421.8 7.3 1.6 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.8 ETS74518.1 - 1.6e-75 252.4 4.7 1.8e-71 239.3 0.4 4.8 5 1 1 6 6 6 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.27 ETS74518.1 - 5.8e-72 242.5 0.0 1e-71 241.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 ETS74518.1 - 4.8e-44 148.8 0.0 4.8e-44 148.8 0.0 3.7 5 0 0 5 5 4 1 FKBP12-rapamycin binding domain FATC PF02260.20 ETS74518.1 - 1.2e-13 50.6 0.2 3.6e-13 49.1 0.2 1.9 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 ETS74518.1 - 4.4e-13 49.4 7.2 0.0037 17.6 0.0 7.0 7 0 0 7 7 5 2 HEAT repeats HEAT PF02985.22 ETS74518.1 - 2.5e-12 45.9 17.4 0.019 15.2 0.0 10.5 12 0 0 12 12 10 3 HEAT repeat HEAT_EZ PF13513.6 ETS74518.1 - 2.6e-11 43.7 7.6 0.015 15.8 0.2 9.5 8 1 1 9 9 9 2 HEAT-like repeat Cnd1 PF12717.7 ETS74518.1 - 8.1e-06 26.0 2.6 0.03 14.4 0.0 5.3 3 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ETS74518.1 - 0.00059 18.5 6.1 0.053 12.1 0.1 4.7 4 1 1 5 5 5 1 Adaptin N terminal region Cohesin_HEAT PF12765.7 ETS74518.1 - 0.047 14.0 0.4 15 6.0 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion ANAPC3 PF12895.7 ETS74518.1 - 0.091 13.0 8.6 6 7.2 0.4 4.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 API5 PF05918.11 ETS74518.1 - 0.46 9.2 7.2 1.7 7.4 0.1 3.1 4 0 0 4 4 4 0 Apoptosis inhibitory protein 5 (API5) Sec7_N PF12783.7 ETS74518.1 - 0.5 10.3 6.7 19 5.1 0.0 4.8 5 0 0 5 5 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Rtf2 PF04641.12 ETS74519.1 - 2e-48 165.0 5.3 2.6e-48 164.7 5.3 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 ETS74519.1 - 0.008 16.1 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 ETS74519.1 - 0.017 15.4 0.1 0.036 14.4 0.1 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 ETS74519.1 - 0.051 13.6 0.0 0.24 11.5 0.0 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zinc_ribbon_15 PF17032.5 ETS74519.1 - 0.15 12.9 0.3 0.37 11.6 0.3 1.7 1 0 0 1 1 1 0 zinc-ribbon family zf-C3HC4_2 PF13923.6 ETS74519.1 - 0.24 11.3 1.3 2 8.3 1.3 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PRTP PF01366.18 ETS74519.1 - 0.78 7.7 5.3 1.1 7.3 5.3 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein PRKCSH-like PF12999.7 ETS74520.1 - 1.4e-38 132.5 13.2 1.2e-23 83.8 4.6 3.2 3 1 1 4 4 4 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 ETS74520.1 - 1.2e-29 103.0 1.5 1.2e-29 103.0 1.5 2.2 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 ETS74520.1 - 1.6e-11 45.0 1.8 1.6e-11 45.0 1.8 2.1 2 0 0 2 2 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 ETS74520.1 - 0.0015 18.5 0.5 0.0032 17.4 0.5 1.6 1 0 0 1 1 1 1 Autophagy-related protein 27 DUF4200 PF13863.6 ETS74520.1 - 0.0061 17.0 14.7 0.0061 17.0 14.7 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) Mod_r PF07200.13 ETS74520.1 - 0.017 15.2 8.4 0.91 9.6 3.9 2.8 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein TolA PF06519.11 ETS74520.1 - 0.017 15.3 0.0 0.058 13.6 0.0 1.9 2 0 0 2 2 1 0 TolA C-terminal Ldl_recept_a PF00057.18 ETS74520.1 - 0.032 14.5 1.7 0.032 14.5 1.7 2.6 2 0 0 2 2 1 0 Low-density lipoprotein receptor domain class A V_ATPase_I PF01496.19 ETS74520.1 - 0.063 11.2 4.2 0.11 10.4 4.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CASP_C PF08172.12 ETS74520.1 - 0.074 12.4 2.5 0.15 11.3 2.5 1.4 1 0 0 1 1 1 0 CASP C terminal Ax_dynein_light PF10211.9 ETS74520.1 - 0.16 11.9 6.8 0.52 10.2 6.8 1.9 1 0 0 1 1 1 0 Axonemal dynein light chain Osmo_CC PF08946.10 ETS74520.1 - 0.17 12.2 5.6 0.23 11.7 3.6 2.3 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Vps5 PF09325.10 ETS74520.1 - 0.28 10.7 9.4 1.7 8.1 8.6 2.3 2 0 0 2 2 2 0 Vps5 C terminal like GLE1 PF07817.13 ETS74520.1 - 0.31 10.2 1.2 0.58 9.3 1.2 1.4 1 0 0 1 1 1 0 GLE1-like protein DUF3106 PF11304.8 ETS74520.1 - 0.78 10.2 6.8 0.45 11.0 4.4 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF3106) DUF4407 PF14362.6 ETS74520.1 - 0.78 9.0 13.0 0.95 8.8 8.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.20 ETS74520.1 - 0.78 9.7 14.1 0.072 13.1 6.7 2.9 3 1 0 3 3 3 0 Prefoldin subunit Effector_1 PF04518.12 ETS74520.1 - 1.2 8.2 3.1 5.1 6.1 1.5 2.1 2 0 0 2 2 2 0 Effector from type III secretion system DUF3486 PF11985.8 ETS74520.1 - 1.4 9.3 8.7 10 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3486) 5_nucleotid PF05761.14 ETS74520.1 - 1.5 7.7 4.1 2.4 7.0 4.1 1.2 1 0 0 1 1 1 0 5' nucleotidase family Fzo_mitofusin PF04799.13 ETS74520.1 - 1.8 8.1 5.0 4.1 6.9 3.5 2.1 2 0 0 2 2 2 0 fzo-like conserved region DUF2408 PF10303.9 ETS74520.1 - 2.6 8.6 8.7 2 9.0 6.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) YabA PF06156.13 ETS74520.1 - 2.6 8.7 6.3 19 5.9 4.7 2.6 2 0 0 2 2 2 0 Initiation control protein YabA DUF3450 PF11932.8 ETS74520.1 - 3 7.1 8.0 1.8 7.8 5.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 ETS74520.1 - 3.6 6.7 5.8 6.5 5.9 5.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF641 PF04859.12 ETS74520.1 - 3.8 7.9 9.6 12 6.2 7.5 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Fmp27_WPPW PF10359.9 ETS74520.1 - 6.3 5.5 11.2 14 4.4 11.3 1.6 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spc24 PF08286.11 ETS74520.1 - 7 6.9 8.3 5 7.4 4.7 2.7 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 PHO4 PF01384.20 ETS74521.1 - 5.6e-103 344.5 21.4 6.6e-103 344.3 21.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family S-antigen PF05756.11 ETS74521.1 - 0.051 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 S-antigen protein UPF0444 PF15475.6 ETS74521.1 - 0.69 10.2 7.5 1.6 9.1 0.5 2.9 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 Gin PF10764.9 ETS74522.1 - 0.036 14.0 0.4 0.057 13.4 0.4 1.3 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin Vint PF14623.6 ETS74523.1 - 6.7e-56 188.7 0.0 1.1e-55 188.0 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 ETS74523.1 - 2.4e-21 75.6 0.0 4.8e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 ETS74523.1 - 2.2e-15 57.3 0.0 5.9e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 ETS74523.1 - 7.2e-14 52.3 0.1 2.9e-13 50.4 0.0 2.0 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA_3 PF13768.6 ETS74523.1 - 2.8e-11 43.6 0.0 9.7e-10 38.6 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain HATPase_c PF02518.26 ETS74524.1 - 2.6e-22 79.5 0.0 6.4e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ETS74524.1 - 3.4e-22 78.7 0.2 7.5e-22 77.6 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 ETS74524.1 - 3.2e-09 37.0 0.0 0.062 13.6 0.0 3.7 3 1 0 3 3 3 3 PAS fold HisKA PF00512.25 ETS74524.1 - 1.5e-07 31.4 0.1 2.2e-06 27.6 0.1 2.7 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 ETS74524.1 - 3.1e-07 30.3 0.0 0.0079 16.2 0.0 3.2 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 ETS74524.1 - 4.6e-05 23.6 0.1 0.0047 17.2 0.1 2.6 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 ETS74524.1 - 0.00048 20.3 0.0 2.1 8.6 0.0 3.9 3 1 0 3 3 3 1 PAS domain GAF_2 PF13185.6 ETS74524.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 GAF domain Cytochrom_C_2 PF01322.20 ETS74525.1 - 0.57 11.1 2.1 6.3 7.7 0.2 2.8 2 0 0 2 2 2 0 Cytochrome C' Acetyltransf_7 PF13508.7 ETS74526.1 - 5.3e-06 26.8 0.0 0.00031 21.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS74526.1 - 1.6e-05 24.8 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS74526.1 - 7.5e-05 22.9 0.0 0.00073 19.8 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ETS74526.1 - 0.00025 20.9 0.0 0.00047 20.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 ETS74526.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ETS74526.1 - 0.016 15.9 0.2 0.031 14.9 0.1 1.6 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain ADH_zinc_N PF00107.26 ETS74527.1 - 0.00034 20.6 0.0 0.00066 19.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase EamA PF00892.20 ETS74528.1 - 2.1e-26 92.7 35.0 4.9e-15 55.9 14.3 2.0 2 0 0 2 2 2 2 EamA-like transporter family DUF2070 PF09843.9 ETS74528.1 - 0.12 10.7 20.3 0.038 12.3 0.7 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2070) ABC2_membrane PF01061.24 ETS74529.1 - 2.1e-90 301.8 63.0 5.3e-47 159.9 24.9 3.2 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 ETS74529.1 - 3.1e-34 116.7 2.5 3e-30 104.0 0.3 3.6 4 0 0 4 4 3 2 CDR ABC transporter ABC_tran PF00005.27 ETS74529.1 - 6.6e-34 117.4 0.0 4.3e-16 59.7 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 ETS74529.1 - 9.8e-14 51.7 0.1 2.8e-13 50.3 0.1 1.9 1 1 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 ETS74529.1 - 4.1e-07 29.8 0.1 1.3e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ETS74529.1 - 6.9e-07 29.5 0.1 0.0036 17.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ETS74529.1 - 4.1e-06 27.3 0.2 0.0013 19.2 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 ETS74529.1 - 1.3e-05 25.7 0.0 0.0024 18.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ETS74529.1 - 1.7e-05 24.5 0.9 0.0021 17.8 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ETS74529.1 - 1.9e-05 24.6 0.0 0.0026 17.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 ETS74529.1 - 4.7e-05 23.4 0.6 0.35 10.6 0.0 2.6 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETS74529.1 - 0.001 18.5 0.0 2.2 7.6 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 ETS74529.1 - 0.0016 18.2 0.6 0.094 12.4 0.3 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 ETS74529.1 - 0.0022 18.4 0.1 2 8.8 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ETS74529.1 - 0.0033 17.7 0.4 0.83 9.9 0.1 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ETS74529.1 - 0.0038 17.2 0.1 0.66 9.9 0.1 2.5 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 ETS74529.1 - 0.0051 16.4 0.6 0.11 12.1 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 ETS74529.1 - 0.017 15.6 0.2 9 6.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 ETS74529.1 - 0.021 15.1 0.3 0.46 10.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ETS74529.1 - 0.051 13.3 0.0 12 5.6 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 ETS74529.1 - 0.066 13.7 0.3 0.16 12.5 0.1 1.6 2 0 0 2 2 1 0 AAA domain DUF1345 PF07077.11 ETS74529.1 - 0.098 12.4 6.3 4.3 7.0 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) Rad17 PF03215.15 ETS74529.1 - 0.11 12.5 0.0 7.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 ETS74529.1 - 0.11 12.6 0.0 6.5 6.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 ETS74529.1 - 0.17 11.6 0.5 14 5.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain GAS PF13851.6 ETS74531.1 - 0.0012 18.2 4.7 0.002 17.5 4.7 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 ETS74531.1 - 0.0017 18.6 13.5 0.01 16.1 13.0 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 ETS74531.1 - 0.0025 18.0 3.5 0.0069 16.6 3.5 1.7 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family SlyX PF04102.12 ETS74531.1 - 0.019 15.6 13.9 1.6 9.4 2.0 3.1 1 1 1 2 2 2 0 SlyX BRE1 PF08647.11 ETS74531.1 - 0.046 13.8 4.7 0.099 12.7 4.7 1.6 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Lebercilin PF15619.6 ETS74531.1 - 0.046 13.4 8.0 0.095 12.3 7.9 1.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease HAUS6_N PF14661.6 ETS74531.1 - 0.067 12.8 1.0 0.11 12.1 1.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4407 PF14362.6 ETS74531.1 - 0.15 11.4 5.4 0.26 10.6 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 ETS74531.1 - 0.2 10.3 1.2 0.31 9.6 1.2 1.3 1 0 0 1 1 1 0 AAA domain ZapB PF06005.12 ETS74531.1 - 0.32 11.5 9.1 1.9 9.0 6.4 2.4 2 0 0 2 2 2 0 Cell division protein ZapB DUF724 PF05266.14 ETS74531.1 - 0.41 10.4 5.0 0.78 9.5 4.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) TMCO5 PF14992.6 ETS74531.1 - 0.58 9.7 4.3 0.9 9.1 4.3 1.2 1 0 0 1 1 1 0 TMCO5 family TMF_DNA_bd PF12329.8 ETS74531.1 - 0.63 10.1 6.8 1.4 9.0 4.2 2.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.12 ETS74531.1 - 0.86 10.1 9.1 24 5.5 7.4 3.1 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein Med9 PF07544.13 ETS74531.1 - 1.1 9.4 4.8 30 4.8 2.0 2.8 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Spc7 PF08317.11 ETS74531.1 - 1.4 7.7 8.6 2.4 7.0 8.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF16 PF01519.16 ETS74531.1 - 1.8 9.1 7.8 11 6.6 5.9 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 SpecificRecomb PF10136.9 ETS74531.1 - 2.7 6.2 6.1 0.77 8.0 3.2 1.4 2 0 0 2 2 2 0 Site-specific recombinase BLOC1_2 PF10046.9 ETS74531.1 - 5.7 7.3 7.7 56 4.1 1.4 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KxDL PF10241.9 ETS74531.1 - 7.3 6.9 10.6 7.6 6.9 4.7 2.6 2 1 1 3 3 2 0 Uncharacterized conserved protein DivIC PF04977.15 ETS74531.1 - 8.2 6.3 13.3 31 4.4 9.2 2.5 1 1 0 2 2 2 0 Septum formation initiator Fungal_trans PF04082.18 ETS74532.1 - 3.9e-31 108.1 0.0 5.9e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS74532.1 - 1.2e-08 35.0 14.1 2e-08 34.2 14.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YjgF_endoribonc PF14588.6 ETS74532.1 - 0.081 13.1 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease CDH-cyt PF16010.5 ETS74533.1 - 1.7e-52 177.8 11.5 1.9e-52 177.6 11.5 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF1996 PF09362.10 ETS74534.1 - 1.4e-70 237.9 3.3 1.9e-70 237.5 3.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Pex16 PF08610.10 ETS74535.1 - 4e-137 456.7 2.5 4.6e-137 456.5 2.5 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) NUDIX PF00293.28 ETS74536.1 - 1.2e-08 35.1 0.2 2.6e-08 34.0 0.2 1.6 1 1 0 1 1 1 1 NUDIX domain SWIRM PF04433.17 ETS74537.1 - 4.5e-12 46.1 0.2 1.7e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain adh_short PF00106.25 ETS74538.1 - 2.2e-40 138.2 0.7 3.7e-40 137.5 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS74538.1 - 3.8e-40 137.9 0.6 8.6e-40 136.7 0.6 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS74538.1 - 1.4e-09 38.1 0.8 3e-09 37.1 0.2 1.7 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.20 ETS74538.1 - 0.00045 20.3 0.0 0.00079 19.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 ETS74538.1 - 0.002 18.1 0.0 0.0072 16.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF1776 PF08643.10 ETS74538.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Sacchrp_dh_NADP PF03435.18 ETS74538.1 - 0.028 14.7 0.2 0.043 14.1 0.2 1.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF1729 PF08354.10 ETS74538.1 - 0.06 12.2 0.2 0.12 11.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) AAA PF00004.29 ETS74539.1 - 1.5e-17 64.3 0.0 6.1e-17 62.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS74539.1 - 3.2e-06 27.5 0.9 0.0028 17.9 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 ETS74539.1 - 0.0012 19.2 2.3 0.013 15.9 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 ETS74539.1 - 0.0034 17.4 0.0 0.0074 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 ETS74539.1 - 0.01 16.1 0.1 0.66 10.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain RuvB_N PF05496.12 ETS74539.1 - 0.049 13.4 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 ETS74539.1 - 0.075 12.6 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ETS74539.1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Abhydrolase_3 PF07859.13 ETS74540.1 - 0.00096 19.1 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 ETS74540.1 - 0.0012 17.6 0.0 0.0081 14.9 0.0 2.0 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 ETS74540.1 - 0.0028 17.2 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 ETS74540.1 - 0.01 15.3 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 ETS74540.1 - 0.044 13.6 0.0 0.072 12.9 0.0 1.5 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Pro-kuma_activ PF09286.11 ETS74541.1 - 6.5e-39 133.5 0.0 1.1e-38 132.7 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ETS74541.1 - 0.0004 19.7 0.9 0.0007 18.9 0.9 1.3 1 0 0 1 1 1 1 Subtilase family SpoU_methylase PF00588.19 ETS74542.1 - 3.9e-27 95.2 0.0 6.9e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 ETS74542.1 - 4.3e-06 26.9 0.0 9.1e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.6 ETS74543.1 - 2.5e-67 225.7 9.4 4.9e-67 224.8 9.4 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 ETS74543.1 - 1.5e-50 171.9 0.0 5.1e-50 170.2 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS74543.1 - 2.1e-17 63.5 0.0 4.8e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 ETS74543.1 - 6.8e-08 32.0 0.6 1.8e-07 30.6 0.6 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 ETS74543.1 - 5.9e-07 29.3 16.4 0.0011 18.8 5.4 3.2 2 1 1 3 3 3 2 PHD-finger Chromo PF00385.24 ETS74543.1 - 0.00031 20.6 4.0 0.0023 17.8 0.1 3.6 4 0 0 4 4 4 1 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 ETS74543.1 - 0.0092 16.0 0.0 0.024 14.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1087 PF06465.13 ETS74543.1 - 0.029 14.4 1.2 0.073 13.1 1.2 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) ERCC3_RAD25_C PF16203.5 ETS74543.1 - 0.04 13.1 0.0 0.087 12.0 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Prok-RING_1 PF14446.6 ETS74543.1 - 0.95 9.4 5.2 0.55 10.2 2.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 ADK_lid PF05191.14 ETS74543.1 - 1.2 9.2 4.0 5.2 7.1 0.1 2.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid Zf_RING PF16744.5 ETS74543.1 - 3.4 7.8 11.1 15 5.8 0.2 3.4 3 0 0 3 3 3 0 KIAA1045 RING finger PHD_2 PF13831.6 ETS74543.1 - 4.3 7.0 10.0 0.05 13.2 0.6 2.6 3 0 0 3 3 3 0 PHD-finger Zip PF02535.22 ETS74544.1 - 1.6 7.9 3.7 2.2 7.4 3.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FapA PF03961.13 ETS74545.1 - 0.0099 14.5 5.8 0.02 13.5 5.8 1.5 1 0 0 1 1 1 1 Flagellar Assembly Protein A DUF3450 PF11932.8 ETS74545.1 - 2.6 7.3 23.8 11 5.3 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 ETS74545.1 - 2.9 5.7 10.0 9.5 4.0 9.1 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 ETS74545.1 - 5.5 6.1 10.2 10 5.2 10.2 1.4 1 0 0 1 1 1 0 TMPIT-like protein Ribosomal_L7Ae PF01248.26 ETS74546.1 - 8.6e-24 83.1 0.0 9.8e-24 82.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.18 ETS74547.1 - 7.7e-45 152.1 0.1 9.7e-45 151.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Myc_N PF01056.18 ETS74548.1 - 2.6 7.9 11.2 0.11 12.4 1.8 2.8 2 1 1 3 3 3 0 Myc amino-terminal region FYDLN_acid PF09538.10 ETS74548.1 - 9.5 7.0 9.7 27 5.5 1.6 3.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF3176 PF11374.8 ETS74549.1 - 5.1e-20 71.7 0.4 5.1e-20 71.7 0.4 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3176) p450 PF00067.22 ETS74550.1 - 2.7e-45 155.0 0.0 3.8e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 ETS74551.1 - 1.6e-06 28.1 12.9 2.6e-06 27.4 12.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS74551.1 - 7.4e-05 21.7 1.5 0.00077 18.4 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF5082 PF16888.5 ETS74552.1 - 0.13 12.6 2.7 0.29 11.4 2.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Fez1 PF06818.15 ETS74552.1 - 0.68 10.4 4.7 1.9 8.9 4.7 1.7 1 0 0 1 1 1 0 Fez1 Pro_isomerase PF00160.21 ETS74553.1 - 2.9e-47 160.9 0.1 4.7e-47 160.2 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 ETS74553.1 - 8.1e-09 34.9 2.9 2.7e-06 27.1 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ETS74553.1 - 2.2e-06 27.4 0.2 7.8e-06 25.7 0.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 ETS74553.1 - 2.2e-06 27.2 1.9 6.8e-06 25.7 0.2 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ETS74553.1 - 0.00014 22.1 0.6 0.0004 20.6 0.3 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 ETS74553.1 - 0.00026 21.6 4.4 0.00026 21.6 4.4 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 ETS74553.1 - 0.0011 19.4 0.9 0.0056 17.2 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ETS74553.1 - 0.0048 17.6 0.5 0.0048 17.6 0.5 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 ETS74553.1 - 0.0094 15.6 3.7 0.3 10.8 0.2 3.1 2 1 0 2 2 2 1 TPR repeat TPR_9 PF13371.6 ETS74553.1 - 0.083 13.0 0.8 0.19 11.9 0.4 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat RasGAP PF00616.19 ETS74554.1 - 2.7e-30 105.6 0.0 3.7e-24 85.6 0.0 3.4 2 1 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 ETS74554.1 - 0.0056 16.9 0.0 0.017 15.4 0.0 1.8 1 1 0 1 1 1 1 C2 domain Opi1 PF08618.10 ETS74554.1 - 3.5 6.8 15.9 9.1 5.4 15.9 1.6 1 0 0 1 1 1 0 Transcription factor Opi1 SOBP PF15279.6 ETS74554.1 - 6.9 7.2 13.8 15 6.1 13.8 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein Sororin PF09666.10 ETS74555.1 - 0.17 12.1 6.8 0.047 13.9 2.6 2.2 2 0 0 2 2 2 0 Sororin protein MRP-L20 PF12824.7 ETS74556.1 - 1.4e-53 181.4 3.2 1.7e-53 181.2 3.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 ETS74556.1 - 0.0089 16.1 0.1 0.014 15.4 0.1 1.4 1 0 0 1 1 1 1 Neugrin Pyridox_ox_2 PF12900.7 ETS74556.1 - 0.068 13.2 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Glyco_trans_2_3 PF13632.6 ETS74558.1 - 2.7e-48 164.5 1.8 9.9e-48 162.7 2.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ETS74558.1 - 6.6e-06 26.0 0.0 0.00038 20.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ETS74558.1 - 0.0048 16.4 0.0 0.014 14.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 ETS74558.1 - 0.099 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Trehalase PF01204.18 ETS74559.1 - 8.4e-191 635.2 0.0 1.1e-190 634.8 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 ETS74559.1 - 3.1e-17 62.0 1.3 5e-17 61.3 1.3 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ICL PF00463.21 ETS74560.1 - 3.5e-298 989.4 0.6 3.9e-298 989.2 0.6 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 ETS74560.1 - 1.6e-11 44.1 0.1 9.8e-11 41.6 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF3197 PF11432.8 ETS74560.1 - 0.0059 16.5 0.5 2.3 8.2 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3197) Sugar_tr PF00083.24 ETS74561.1 - 1e-99 334.5 20.7 1.2e-99 334.3 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS74561.1 - 4.4e-26 91.7 32.6 3.6e-21 75.5 14.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Vps62 PF06101.11 ETS74562.1 - 5e-10 38.3 1.8 7.3e-10 37.8 0.5 1.8 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 Caps_synth PF05704.12 ETS74563.1 - 1.2e-10 41.2 0.0 3.1e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 ETS74563.1 - 0.0029 18.2 0.1 0.0081 16.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Ank_2 PF12796.7 ETS74564.1 - 2.7e-05 24.6 0.0 0.0007 20.1 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS74564.1 - 0.00011 22.6 0.0 1.6 9.4 0.0 3.8 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS74564.1 - 0.002 18.4 0.1 0.57 10.6 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 ETS74564.1 - 0.018 15.5 0.1 0.056 13.9 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 ETS74564.1 - 0.024 15.1 0.1 2.1 9.2 0.0 4.0 6 0 0 6 6 6 0 Ankyrin repeat Inhibitor_I10 PF12559.8 ETS74564.1 - 0.083 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Serine endopeptidase inhibitors Ank_3 PF13606.6 ETS74565.1 - 5.7e-13 47.8 0.1 0.087 13.4 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 ETS74565.1 - 1.4e-12 48.0 0.0 2.3e-05 24.9 0.0 3.2 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS74565.1 - 1.2e-10 41.7 0.1 0.0044 17.6 0.0 4.8 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 ETS74565.1 - 1.5e-06 28.4 0.0 0.69 10.5 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 ETS74565.1 - 3.1e-05 24.2 0.2 0.12 12.7 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS74566.1 - 0.0012 19.4 0.0 0.043 14.4 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS74566.1 - 0.0063 16.9 0.2 12 6.9 0.1 4.5 4 0 0 4 4 4 1 Ankyrin repeat HalX PF08663.10 ETS74566.1 - 0.1 12.9 0.7 17 5.8 0.7 2.4 2 0 0 2 2 2 0 HalX domain Ank_2 PF12796.7 ETS74567.1 - 5.1e-18 65.4 0.7 1e-09 38.9 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS74567.1 - 1.3e-14 52.8 1.1 0.0034 17.8 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 ETS74567.1 - 1.4e-14 53.8 1.4 0.0001 22.6 0.1 5.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 ETS74567.1 - 6.3e-13 49.0 3.2 0.061 13.9 0.1 6.1 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS74567.1 - 3.9e-12 46.1 3.2 0.00076 19.7 0.0 5.4 3 2 3 6 6 6 4 Ankyrin repeats (many copies) F-box-like PF12937.7 ETS74567.1 - 0.00022 21.0 0.0 0.00047 20.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like Filament PF00038.21 ETS74570.1 - 0.0018 17.9 37.1 0.0032 17.1 37.1 1.3 1 0 0 1 1 1 1 Intermediate filament protein MerR-DNA-bind PF09278.11 ETS74570.1 - 0.033 14.7 6.0 0.084 13.4 1.9 3.5 3 1 0 3 3 3 0 MerR, DNA binding DUF1664 PF07889.12 ETS74570.1 - 4.6 7.3 9.5 4.2 7.4 0.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 ETS74570.1 - 4.7 7.7 5.1 46 4.5 0.3 3.9 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) GH-E PF14410.6 ETS74571.1 - 0.075 13.4 2.6 0.3 11.5 0.1 2.7 3 0 0 3 3 3 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Ank_2 PF12796.7 ETS74573.1 - 9.7e-17 61.3 9.6 6.8e-09 36.2 2.0 3.8 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS74573.1 - 7.3e-11 42.1 2.1 0.00096 19.4 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS74573.1 - 4.2e-10 39.6 4.2 0.0001 22.6 0.6 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 ETS74573.1 - 1.4e-08 35.1 3.8 0.0045 17.5 0.2 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS74573.1 - 1.9e-08 33.9 3.9 0.0027 18.0 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat F-box-like PF12937.7 ETS74573.1 - 0.0028 17.5 0.0 0.0066 16.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like Ank_2 PF12796.7 ETS74574.1 - 6e-11 42.8 0.1 2.4e-05 24.8 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS74574.1 - 1e-09 38.7 3.4 0.00096 19.7 0.0 5.6 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS74574.1 - 1.3e-09 38.1 0.3 0.011 16.0 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS74574.1 - 5.2e-09 36.2 1.7 0.053 14.0 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 ETS74574.1 - 1.7e-08 34.1 2.1 0.14 12.8 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat F-box-like PF12937.7 ETS74574.1 - 0.0076 16.1 0.0 0.025 14.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like Nterm_IS4 PF13006.7 ETS74574.1 - 0.074 13.2 0.0 5 7.4 0.0 2.4 2 0 0 2 2 2 0 Insertion element 4 transposase N-terminal DUF4611 PF15387.6 ETS74574.1 - 0.23 11.7 2.0 0.47 10.7 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) FAD_binding_3 PF01494.19 ETS74575.1 - 5e-29 101.6 0.1 1.8e-28 99.8 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 ETS74575.1 - 1.3e-06 28.0 0.8 0.00017 21.0 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 ETS74575.1 - 1.4e-06 28.2 2.8 9.5e-05 22.1 0.7 2.6 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS74575.1 - 2.1e-06 27.2 0.2 0.0068 15.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS74575.1 - 2.2e-06 27.1 1.6 0.0033 16.7 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS74575.1 - 1e-05 24.8 4.5 2.9e-05 23.3 2.1 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ETS74575.1 - 0.00026 21.2 0.6 0.00074 19.7 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS74575.1 - 0.0033 17.4 1.8 0.98 9.4 0.1 2.8 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 ETS74575.1 - 0.0039 17.7 1.0 0.11 13.0 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ETS74575.1 - 0.0041 16.0 1.6 0.028 13.3 0.1 2.2 1 1 1 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 ETS74575.1 - 0.036 13.1 1.6 0.066 12.3 0.5 1.9 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 ETS74575.1 - 0.043 13.2 0.1 0.081 12.3 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS74575.1 - 0.044 12.5 0.2 3.4 6.3 0.1 2.4 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 ETS74575.1 - 0.16 11.2 0.5 0.44 9.7 0.1 1.9 2 0 0 2 2 2 0 Thi4 family Cupin_2 PF07883.11 ETS74576.1 - 3.7e-15 55.4 0.1 4.8e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ETS74576.1 - 6.8e-08 32.2 0.0 8e-08 32.0 0.0 1.0 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 ETS74576.1 - 0.00018 21.1 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 ETS74576.1 - 0.0058 16.5 0.1 0.0089 15.9 0.1 1.3 1 1 0 1 1 1 1 AraC-like ligand binding domain HutD PF05962.11 ETS74576.1 - 0.026 14.5 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 HutD Endosulfine PF04667.17 ETS74577.1 - 5.1e-28 97.0 0.2 8.4e-28 96.3 0.2 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF5349 PF17298.2 ETS74577.1 - 0.0086 15.9 0.2 0.013 15.3 0.1 1.2 1 1 0 1 1 1 1 Family of unknown function (DUF5349) BESS PF02944.20 ETS74577.1 - 0.13 12.1 0.5 0.84 9.5 0.1 2.1 1 1 1 2 2 2 0 BESS motif UPF0160 PF03690.13 ETS74578.1 - 2.5e-130 434.8 0.0 2.8e-130 434.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ino80_Iec3 PF14612.6 ETS74579.1 - 2e-51 175.9 4.8 2e-27 97.4 4.3 2.2 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling RNA_Me_trans PF04252.13 ETS74580.1 - 1.3e-83 279.5 0.0 1.5e-83 279.3 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Pkinase PF00069.25 ETS74581.1 - 0.00069 19.1 0.0 0.0021 17.5 0.0 1.8 2 1 0 2 2 2 1 Protein kinase domain Vac7 PF12751.7 ETS74582.1 - 1.7e-134 449.1 9.8 4.3e-122 408.2 0.7 3.5 3 1 0 3 3 3 2 Vacuolar segregation subunit 7 PRP1_N PF06424.12 ETS74583.1 - 1.1e-52 178.4 7.6 2.5e-52 177.2 7.6 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 ETS74583.1 - 1.8e-36 121.7 34.8 1.8e-05 25.1 0.1 13.5 6 4 9 15 15 14 10 Tetratricopeptide repeat TPR_19 PF14559.6 ETS74583.1 - 1e-29 102.8 8.5 2.5e-09 37.5 0.1 9.6 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 ETS74583.1 - 5.3e-17 62.2 19.2 3.2e-05 24.5 0.4 8.1 4 2 6 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.6 ETS74583.1 - 7.1e-14 51.1 5.5 0.58 10.7 0.0 10.9 12 1 0 12 12 11 2 Tetratricopeptide repeat TPR_2 PF07719.17 ETS74583.1 - 5.2e-13 48.0 11.1 0.38 11.0 0.0 11.1 12 1 1 13 13 12 2 Tetratricopeptide repeat TPR_8 PF13181.6 ETS74583.1 - 7e-11 41.5 1.2 2.6 8.5 0.0 9.2 12 0 0 12 12 10 3 Tetratricopeptide repeat NARP1 PF12569.8 ETS74583.1 - 1.3e-10 40.8 4.0 0.07 12.0 0.0 6.1 5 1 2 7 7 7 3 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 ETS74583.1 - 6.4e-09 35.4 25.9 2.8e-06 26.7 3.8 6.3 3 3 2 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 ETS74583.1 - 1.8e-05 25.1 6.7 68 4.4 0.0 8.7 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 ETS74583.1 - 6.6e-05 23.1 8.3 6.9 7.0 0.2 6.8 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 ETS74583.1 - 0.00016 21.3 3.8 0.42 10.3 0.1 6.1 8 0 0 8 8 8 1 TPR repeat ANAPC3 PF12895.7 ETS74583.1 - 0.0002 21.5 0.2 10 6.4 0.0 5.3 4 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Suf PF05843.14 ETS74583.1 - 0.00085 19.4 0.0 2.3 8.1 0.0 3.8 4 1 1 5 5 5 1 Suppressor of forked protein (Suf) TPR_21 PF09976.9 ETS74583.1 - 0.00092 19.0 6.7 0.0035 17.1 1.3 4.0 3 1 1 4 4 3 1 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 ETS74583.1 - 0.0014 18.5 0.5 12 6.2 0.0 4.7 5 0 0 5 5 3 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 ETS74583.1 - 0.003 17.5 1.8 24 4.8 0.0 5.1 3 1 2 5 5 5 0 Virulence factor membrane-bound polymerase, C-terminal TPR_1 PF00515.28 ETS74583.1 - 0.0068 16.2 0.0 6.2 6.8 0.0 4.7 6 0 0 6 6 5 1 Tetratricopeptide repeat ChAPs PF09295.10 ETS74583.1 - 3.7 6.4 6.4 21 4.0 0.2 3.7 3 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Fungal_trans PF04082.18 ETS74584.1 - 9.4e-23 80.6 0.4 1.5e-22 79.9 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS74584.1 - 4.6e-06 26.7 13.9 7.9e-06 25.9 13.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 ETS74585.1 - 5.5e-72 243.1 25.1 6.4e-72 242.8 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS74585.1 - 6.8e-32 110.8 24.1 6.8e-32 110.8 24.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS74585.1 - 1.5e-07 30.2 3.2 1.5e-07 30.2 3.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 ETS74585.1 - 1.2e-06 27.7 4.5 1.3e-06 27.6 0.4 2.3 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM OATP PF03137.20 ETS74585.1 - 0.00046 18.6 9.5 0.0045 15.4 1.5 2.8 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 ETS74585.1 - 0.00067 18.6 1.9 0.00067 18.6 1.9 2.7 1 1 0 2 2 2 1 MFS_1 like family BT1 PF03092.16 ETS74585.1 - 0.0024 16.2 0.8 0.0024 16.2 0.8 2.3 1 1 1 2 2 2 1 BT1 family Bromo_TP PF07524.13 ETS74585.1 - 0.025 14.6 0.1 0.069 13.2 0.1 1.7 1 0 0 1 1 1 0 Bromodomain associated DUF1479 PF07350.12 ETS74586.1 - 1.9e-114 382.7 0.0 2.3e-114 382.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Amidase PF01425.21 ETS74587.1 - 5e-75 253.2 0.8 1.5e-74 251.6 0.8 1.7 1 1 0 1 1 1 1 Amidase Epimerase PF01370.21 ETS74587.1 - 7.2e-11 42.0 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS74587.1 - 2.2e-08 33.5 0.0 3.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ETS74587.1 - 1.2e-05 25.3 0.0 3.8e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS74587.1 - 0.008 15.8 0.1 0.017 14.7 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 ETS74587.1 - 0.064 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 ETS74587.1 - 0.16 12.2 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Amidase PF01425.21 ETS74588.1 - 6.1e-100 335.3 0.0 2.9e-99 333.1 0.0 1.8 1 1 0 1 1 1 1 Amidase p450 PF00067.22 ETS74589.1 - 2.7e-28 99.0 0.0 3.5e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Transp_cyt_pur PF02133.15 ETS74590.1 - 7.5e-82 275.4 29.9 8.6e-82 275.2 29.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pmp3 PF01679.17 ETS74590.1 - 2.1 8.6 10.6 0.095 12.9 2.2 3.1 3 0 0 3 3 3 0 Proteolipid membrane potential modulator Fungal_trans PF04082.18 ETS74591.1 - 2.9e-13 49.5 0.0 6.1e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPMT PF05724.11 ETS74591.1 - 0.088 12.4 0.1 0.22 11.2 0.1 1.6 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) p450 PF00067.22 ETS74592.1 - 7.9e-54 183.1 0.0 9.5e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 ETS74593.1 - 1.7e-39 135.8 0.2 4.9e-39 134.3 0.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS74593.1 - 3.2e-36 124.6 0.2 6.2e-36 123.7 0.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS74593.1 - 4.2e-09 36.6 3.0 7.5e-08 32.5 0.1 2.1 1 1 1 2 2 2 2 KR domain Epimerase PF01370.21 ETS74593.1 - 0.11 11.9 0.0 2.7 7.4 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF2518 PF10726.9 ETS74593.1 - 0.16 11.6 0.6 0.33 10.6 0.6 1.4 1 0 0 1 1 1 0 Protein of function (DUF2518) Abhydrolase_1 PF00561.20 ETS74594.1 - 2.4e-15 56.9 0.2 7.8e-14 51.9 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS74594.1 - 4.2e-06 27.5 0.0 5.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS74594.1 - 0.00015 21.2 0.0 0.0035 16.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ribonuc_L-PSP PF01042.21 ETS74595.1 - 2.1e-18 66.5 0.0 2.7e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Peptidase_M20 PF01546.28 ETS74596.1 - 5.3e-34 117.7 0.0 8.4e-34 117.1 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ETS74596.1 - 2.4e-13 50.0 0.0 4.3e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain FlaE PF07559.14 ETS74596.1 - 0.028 15.0 0.1 0.055 14.1 0.1 1.4 1 0 0 1 1 1 0 Flagellar basal body protein FlaE DUF4476 PF14771.6 ETS74597.1 - 0.16 12.3 0.1 0.28 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Apolipoprotein PF01442.18 ETS74598.1 - 0.0069 16.3 7.6 0.013 15.4 7.6 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Vps51 PF08700.11 ETS74598.1 - 0.091 12.8 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 Vps51/Vps67 Borrelia_P83 PF05262.11 ETS74598.1 - 3.2 6.1 12.9 4.1 5.8 12.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein OmpH PF03938.14 ETS74598.1 - 7 7.0 14.0 13 6.1 14.0 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ATP-synt_B PF00430.18 ETS74598.1 - 8.3 6.5 19.5 8 6.6 8.3 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) RrnaAD PF00398.20 ETS74599.1 - 1e-60 205.1 0.0 1.5e-60 204.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 ETS74599.1 - 6.6e-08 33.2 0.0 1.3e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS74599.1 - 7.7e-06 26.5 0.0 1.7e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ETS74599.1 - 0.00014 21.3 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 ETS74599.1 - 0.0002 21.2 0.0 0.0003 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 ETS74599.1 - 0.00056 19.3 0.0 0.00092 18.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ETS74599.1 - 0.0021 17.9 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS74599.1 - 0.0025 17.7 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS74599.1 - 0.0041 17.8 0.0 0.011 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain AAA_lid_4 PF17864.1 ETS74599.1 - 0.0054 16.5 0.2 0.011 15.5 0.2 1.4 1 0 0 1 1 1 1 RuvB AAA lid domain MTS PF05175.14 ETS74599.1 - 0.02 14.5 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 ETS74599.1 - 0.024 14.1 0.0 0.055 12.9 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Cons_hypoth95 PF03602.15 ETS74599.1 - 0.027 14.1 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PrmA PF06325.13 ETS74599.1 - 0.028 13.8 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF43 PF01861.16 ETS74599.1 - 0.057 12.6 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain UPF0020 PF01170.18 ETS74599.1 - 0.088 12.5 0.0 0.28 10.8 0.0 1.8 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_28 PF02636.17 ETS74599.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Met_10 PF02475.16 ETS74599.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein NodS PF05401.11 ETS74599.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_18 PF12847.7 ETS74599.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Sigma70_ner PF04546.13 ETS74599.1 - 0.83 9.5 5.3 1.2 8.9 5.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PPR_2 PF13041.6 ETS74600.1 - 0.00018 21.6 0.0 0.16 12.2 0.0 2.5 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.20 ETS74600.1 - 0.0055 16.9 0.8 0.11 12.8 0.0 2.8 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.6 ETS74600.1 - 0.016 15.2 0.0 8.3 6.6 0.0 2.8 2 1 1 3 3 3 0 Pentatricopeptide repeat domain PP2C PF00481.21 ETS74601.1 - 5e-82 275.4 0.0 7.6e-82 274.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C He_PIG PF05345.12 ETS74602.1 - 1.2e-10 41.4 4.7 0.01 16.0 0.2 4.2 3 0 0 3 3 3 3 Putative Ig domain TMEM154 PF15102.6 ETS74602.1 - 3.6e-05 23.7 0.1 0.0001 22.2 0.1 1.8 1 0 0 1 1 1 1 TMEM154 protein family SKG6 PF08693.10 ETS74602.1 - 0.0023 17.3 2.8 0.0064 15.9 2.8 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain BatD PF13584.6 ETS74602.1 - 0.0055 15.6 0.0 0.0085 14.9 0.0 1.2 1 0 0 1 1 1 1 Oxygen tolerance Adeno_E3_CR2 PF02439.15 ETS74602.1 - 0.0064 16.2 1.7 0.016 14.9 1.7 1.7 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF4448 PF14610.6 ETS74602.1 - 0.0064 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Alpha_GJ PF03229.13 ETS74602.1 - 0.044 14.3 0.8 0.16 12.5 0.8 2.0 1 0 0 1 1 1 0 Alphavirus glycoprotein J Methyltransf_16 PF10294.9 ETS74603.1 - 7.3e-43 146.3 0.0 9.1e-43 146.0 0.0 1.0 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 ETS74603.1 - 0.017 14.6 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 ETS74603.1 - 0.044 13.4 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 SOG2 PF10428.9 ETS74604.1 - 0.052 12.8 11.9 0.066 12.4 11.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Abhydrolase_6 PF12697.7 ETS74605.1 - 2e-09 38.4 8.2 2.5e-09 38.1 8.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ETS74605.1 - 0.0092 15.8 0.1 0.023 14.4 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PHB_acc PF05233.13 ETS74605.1 - 0.015 15.3 0.1 0.03 14.4 0.1 1.5 1 0 0 1 1 1 0 PHB accumulation regulatory domain DUF3000 PF11452.8 ETS74605.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) DUF3433 PF11915.8 ETS74606.1 - 1e-39 134.9 12.2 3.2e-21 75.6 2.0 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) AA_permease_2 PF13520.6 ETS74606.1 - 0.27 10.0 3.4 2.4 6.9 0.0 3.0 3 0 0 3 3 3 0 Amino acid permease DUF202 PF02656.15 ETS74606.1 - 1.2 9.6 7.4 14 6.3 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF202) Orai-1 PF07856.12 ETS74606.1 - 1.7 8.3 8.7 0.44 10.2 4.0 2.4 2 1 0 2 2 2 0 Mediator of CRAC channel activity TRP PF06011.12 ETS74607.1 - 1.7e-161 537.7 32.9 2e-161 537.5 32.9 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 ETS74607.1 - 5.6e-46 156.4 1.6 9.4e-46 155.6 1.6 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 ETS74607.1 - 0.00019 21.9 0.2 0.00033 21.1 0.2 1.4 1 0 0 1 1 1 1 ML domain GTP_CH_N PF12471.8 ETS74607.1 - 0.045 13.5 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal Neur_chan_memb PF02932.16 ETS74607.1 - 0.099 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TcpE PF12648.7 ETS74607.1 - 1.8 9.1 15.1 1.6 9.3 5.3 3.2 2 1 0 2 2 2 0 TcpE family Orf78 PF06024.12 ETS74607.1 - 3.4 8.0 4.0 49 4.3 1.3 2.6 2 0 0 2 2 2 0 Orf78 (ac78) DUF1712 PF08217.11 ETS74608.1 - 4.8e-13 48.5 0.0 1.2e-08 34.0 0.0 3.1 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Cript PF10235.9 ETS74609.1 - 0.027 15.0 2.6 0.035 14.7 0.1 2.0 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT Pec_lyase_C PF00544.19 ETS74610.1 - 1.3e-42 145.8 8.5 1.9e-42 145.3 8.5 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 ETS74610.1 - 2.6e-05 24.1 11.4 0.00036 20.4 10.4 2.4 1 1 0 1 1 1 1 Right handed beta helix region HpcH_HpaI PF03328.14 ETS74612.1 - 1.7e-28 99.3 0.0 2.2e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 ETS74612.1 - 0.00024 20.3 0.1 0.01 15.0 0.1 2.7 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain C-C_Bond_Lyase PF15617.6 ETS74612.1 - 0.079 12.1 0.0 0.18 10.9 0.0 1.6 1 1 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold Iso_dh PF00180.20 ETS74613.1 - 7.8e-74 248.9 0.0 9.1e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_hydro_3 PF00933.21 ETS74614.1 - 2.4e-40 138.9 0.0 3.5e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 ETS74614.1 - 2.7e-40 138.5 0.0 5.1e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ETS74614.1 - 4.4e-25 87.6 0.0 8.4e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Patatin PF01734.22 ETS74615.1 - 5.7e-25 88.7 0.0 1.8e-24 87.0 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase FOXP-CC PF16159.5 ETS74617.1 - 0.0047 17.5 5.9 0.23 12.1 1.2 2.6 1 1 1 2 2 2 2 FOXP coiled-coil domain TFIIIC_sub6 PF10419.9 ETS74618.1 - 4.5e-26 90.5 0.0 8e-26 89.8 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain His_biosynth PF00977.21 ETS74619.1 - 9.2e-51 172.5 0.5 3.2e-50 170.7 0.5 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 ETS74619.1 - 1.2e-21 77.3 0.0 2e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 ETS74619.1 - 1.6e-10 41.1 0.0 6.2e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 ETS74619.1 - 3e-07 30.2 0.0 7.9e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 ETS74619.1 - 0.014 15.2 0.1 0.063 13.0 0.1 2.0 1 1 0 1 1 1 0 Peptidase C26 DJ-1_PfpI PF01965.24 ETS74619.1 - 0.063 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family ODC_AZ PF02100.17 ETS74620.1 - 7.7e-45 151.5 0.4 9.3e-45 151.3 0.4 1.1 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Yippee-Mis18 PF03226.14 ETS74621.1 - 7.5e-21 74.3 0.1 1.2e-20 73.7 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 ETS74621.1 - 0.0074 16.5 0.2 0.32 11.2 0.0 2.1 2 0 0 2 2 2 1 C-terminal domain of RIG-I Tyr_Deacylase PF02580.16 ETS74622.1 - 1.1e-53 181.6 0.2 1.3e-53 181.4 0.2 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.15 ETS74623.1 - 5.9e-89 297.5 28.2 1.3e-88 296.3 28.2 1.6 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 ETS74623.1 - 3.6e-43 146.8 11.6 9.1e-43 145.5 11.6 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 ETS74623.1 - 0.0034 17.7 1.8 0.0034 17.7 1.8 3.0 3 1 0 3 3 3 1 Syntaxin-like protein DUF2373 PF10180.9 ETS74623.1 - 0.014 15.2 2.4 0.035 13.9 2.4 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Sec5 PF15469.6 ETS74623.1 - 0.17 11.7 7.2 0.11 12.3 0.5 2.4 2 0 0 2 2 2 0 Exocyst complex component Sec5 Rx_N PF18052.1 ETS74623.1 - 2.8 8.3 7.0 9.1 6.6 1.7 3.0 2 0 0 2 2 2 0 Rx N-terminal domain HeLo PF14479.6 ETS74623.1 - 3.9 7.3 14.4 13 5.5 11.2 2.5 2 0 0 2 2 2 0 Prion-inhibition and propagation OrfB_IS605 PF01385.19 ETS74623.1 - 7.4 6.8 8.7 2.8 8.2 0.6 3.1 3 0 0 3 3 3 0 Probable transposase Arrestin_N PF00339.29 ETS74624.1 - 9.6e-15 54.9 0.0 6.4e-10 39.3 0.0 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 ETS74624.1 - 0.26 10.7 0.0 0.46 9.9 0.0 1.3 1 0 0 1 1 1 0 Bul1 C terminus Formyl_trans_N PF00551.19 ETS74625.1 - 1.5e-25 90.0 0.0 2.4e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase HABP4_PAI-RBP1 PF04774.15 ETS74626.1 - 0.021 15.7 3.8 0.036 14.9 3.8 1.4 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family CIAPIN1 PF05093.13 ETS74627.1 - 3.4e-41 139.8 3.6 5.7e-41 139.1 3.6 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 ETS74627.1 - 1.1e-37 129.2 0.0 1.6e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus zf-MIZ PF02891.20 ETS74628.1 - 4.3e-07 29.6 6.9 2.8e-05 23.8 6.9 2.5 1 1 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 ETS74628.1 - 0.094 12.6 0.1 0.26 11.1 0.1 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SAM_2 PF07647.17 ETS74629.1 - 2.3e-13 50.1 0.0 4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 ETS74629.1 - 2.9e-13 49.5 0.0 5.8e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ETS74629.1 - 6.5e-11 41.7 0.0 1.3e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 ETS74629.1 - 4.8e-09 36.7 0.0 2e-08 34.7 0.0 2.0 1 1 0 1 1 1 1 PH domain SH3_2 PF07653.17 ETS74629.1 - 0.00028 20.5 0.0 0.00069 19.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 ETS74629.1 - 0.0011 19.4 0.0 0.0027 18.1 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 ETS74629.1 - 0.05 13.9 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain SAM_1 PF00536.30 ETS74629.1 - 0.052 14.0 0.1 0.1 13.1 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 ETS74629.1 - 0.12 12.4 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain YrbL-PhoP_reg PF10707.9 ETS74630.1 - 0.011 15.3 0.0 0.031 13.8 0.0 1.6 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL Peptidase_S10 PF00450.22 ETS74631.1 - 6.4e-113 378.3 0.1 8.2e-113 377.9 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Cation_efflux PF01545.21 ETS74631.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Cation efflux family FAD_binding_3 PF01494.19 ETS74632.1 - 2e-09 37.2 7.3 1.1e-07 31.5 2.2 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS74632.1 - 0.0038 17.4 0.4 0.014 15.6 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SUIM_assoc PF16619.5 ETS74632.1 - 0.0046 17.0 0.3 0.091 12.8 0.6 2.3 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 SE PF08491.10 ETS74632.1 - 0.07 12.2 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Squalene epoxidase NAD_binding_9 PF13454.6 ETS74632.1 - 0.54 10.2 4.6 4.1 7.4 0.3 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ETS74632.1 - 0.98 8.4 5.3 3.9 6.4 0.1 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein DAO PF01266.24 ETS74632.1 - 8.6 5.8 9.9 0.39 10.2 1.0 2.6 2 1 1 3 3 3 0 FAD dependent oxidoreductase PGAP1 PF07819.13 ETS74633.1 - 2.6e-07 30.6 0.3 4.5e-07 29.8 0.3 1.3 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 ETS74633.1 - 5.7e-06 26.4 0.0 9.9e-06 25.6 0.0 1.4 2 0 0 2 2 2 1 Palmitoyl protein thioesterase DUF676 PF05057.14 ETS74633.1 - 3.1e-05 23.6 0.0 5.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 ETS74633.1 - 0.00057 19.2 0.0 0.00091 18.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 ETS74633.1 - 0.00065 19.4 0.3 0.075 12.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS74633.1 - 0.0015 19.2 4.1 0.0031 18.2 4.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 ETS74633.1 - 0.0078 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.18 ETS74633.1 - 0.067 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 2) Ser_hydrolase PF06821.13 ETS74633.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase RTA1 PF04479.13 ETS74634.1 - 4.2e-39 134.3 9.6 5.7e-39 133.9 9.6 1.2 1 0 0 1 1 1 1 RTA1 like protein RicinB_lectin_2 PF14200.6 ETS74635.1 - 2.3e-20 73.1 5.1 2.9e-13 50.4 0.8 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 ETS74635.1 - 2.3e-06 27.9 0.3 7.4e-06 26.2 0.3 2.0 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Phage_GP20 PF06810.11 ETS74636.1 - 0.0026 17.6 0.6 0.0026 17.6 0.6 2.3 2 1 1 3 3 3 1 Phage minor structural protein GP20 DUF1690 PF07956.11 ETS74636.1 - 0.021 15.2 4.0 0.14 12.6 0.6 2.1 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) FlxA PF14282.6 ETS74636.1 - 0.029 14.4 6.9 0.051 13.6 1.6 2.4 2 0 0 2 2 2 0 FlxA-like protein Med9 PF07544.13 ETS74636.1 - 0.051 13.7 0.9 0.33 11.1 0.2 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 PspA_IM30 PF04012.12 ETS74636.1 - 0.12 11.9 4.5 0.16 11.5 0.1 2.2 3 0 0 3 3 3 0 PspA/IM30 family WXG100 PF06013.12 ETS74636.1 - 0.19 12.0 4.0 0.2 11.9 0.7 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Seryl_tRNA_N PF02403.22 ETS74636.1 - 0.3 11.3 3.6 1 9.6 2.1 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BST2 PF16716.5 ETS74636.1 - 1 10.0 6.6 3.5 8.3 1.2 2.5 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 End3 PF12761.7 ETS74636.1 - 1.8 8.7 8.4 10 6.2 8.4 1.9 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 SlyX PF04102.12 ETS74636.1 - 4.8 7.9 9.5 0.77 10.4 1.5 2.8 3 0 0 3 3 3 0 SlyX ALIX_LYPXL_bnd PF13949.6 ETS74637.1 - 1.2e-05 24.8 5.7 1.4e-05 24.5 5.7 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF2935 PF11155.8 ETS74637.1 - 0.00058 20.2 1.0 0.00077 19.8 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2935) STAT_alpha PF01017.20 ETS74637.1 - 0.0014 18.6 2.6 0.0017 18.3 2.6 1.2 1 0 0 1 1 1 1 STAT protein, all-alpha domain ATG16 PF08614.11 ETS74637.1 - 0.0038 17.5 6.9 0.0053 17.0 6.9 1.3 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Ran-binding PF05508.11 ETS74637.1 - 0.0056 15.7 1.9 0.0071 15.4 1.9 1.1 1 0 0 1 1 1 1 RanGTP-binding protein CLZ PF16526.5 ETS74637.1 - 0.0063 16.8 4.4 0.047 14.0 1.0 2.2 1 1 1 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SKA2 PF16740.5 ETS74637.1 - 0.0068 16.2 3.3 0.12 12.2 0.8 2.2 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 2 ATPase PF06745.13 ETS74637.1 - 0.0094 15.3 0.7 0.01 15.2 0.7 1.1 1 0 0 1 1 1 1 KaiC BAR_3 PF16746.5 ETS74637.1 - 0.012 15.3 3.4 0.013 15.3 3.4 1.1 1 0 0 1 1 1 0 BAR domain of APPL family Sec34 PF04136.15 ETS74637.1 - 0.016 15.1 6.5 0.048 13.5 6.5 1.7 1 1 0 1 1 1 0 Sec34-like family GAS PF13851.6 ETS74637.1 - 0.017 14.5 9.2 0.024 14.0 9.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mod_r PF07200.13 ETS74637.1 - 0.02 15.0 4.4 0.018 15.1 3.6 1.5 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF2959 PF11172.8 ETS74637.1 - 0.02 15.1 3.3 0.034 14.3 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2959) CAP_N PF01213.19 ETS74637.1 - 0.027 13.9 0.6 0.03 13.8 0.6 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CENP-F_leu_zip PF10473.9 ETS74637.1 - 0.028 14.4 6.5 0.037 14.1 5.7 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 ETS74637.1 - 0.029 14.7 8.0 0.12 12.7 8.0 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3144 PF11342.8 ETS74637.1 - 0.029 14.7 0.9 0.12 12.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3144) TMF_TATA_bd PF12325.8 ETS74637.1 - 0.031 14.5 6.4 0.042 14.1 6.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding WXG100 PF06013.12 ETS74637.1 - 0.037 14.3 0.9 1.5 9.1 0.1 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG ApoB100_C PF12491.8 ETS74637.1 - 0.048 13.6 1.2 0.21 11.6 0.1 2.2 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal NYD-SP28 PF14772.6 ETS74637.1 - 0.049 13.7 7.3 3.1 7.9 0.1 2.4 1 1 1 2 2 2 0 Sperm tail DUF2894 PF11445.8 ETS74637.1 - 0.053 14.0 0.4 0.062 13.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) T3SSipB PF16535.5 ETS74637.1 - 0.057 13.9 2.0 0.7 10.4 1.5 2.0 1 1 1 2 2 2 0 Type III cell invasion protein SipB GrpE PF01025.19 ETS74637.1 - 0.059 13.0 6.3 0.08 12.6 6.3 1.3 1 0 0 1 1 1 0 GrpE UPF0242 PF06785.11 ETS74637.1 - 0.064 13.4 5.9 0.078 13.1 5.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4358 PF14270.6 ETS74637.1 - 0.071 13.4 1.3 0.14 12.5 0.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4358) PIN_8 PF18476.1 ETS74637.1 - 0.077 12.8 3.7 0.09 12.6 3.7 1.1 1 0 0 1 1 1 0 PIN like domain FapA PF03961.13 ETS74637.1 - 0.096 11.3 5.3 0.11 11.0 5.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Mt_ATP-synt_D PF05873.12 ETS74637.1 - 0.1 12.4 1.4 1.7 8.5 1.4 2.0 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF3450 PF11932.8 ETS74637.1 - 0.11 11.7 4.6 0.2 11.0 4.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) ALMT PF11744.8 ETS74637.1 - 0.16 10.8 3.7 0.16 10.8 3.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1664 PF07889.12 ETS74637.1 - 0.17 11.9 1.5 1.2 9.2 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ParB PF08775.10 ETS74637.1 - 0.19 12.2 3.5 0.36 11.3 3.1 1.6 1 1 1 2 2 2 0 ParB family PCRF PF03462.18 ETS74637.1 - 0.19 11.5 3.2 0.22 11.4 3.2 1.1 1 0 0 1 1 1 0 PCRF domain Tropomyosin_1 PF12718.7 ETS74637.1 - 0.25 11.5 10.1 0.31 11.2 10.1 1.3 1 0 0 1 1 1 0 Tropomyosin like DUF948 PF06103.11 ETS74637.1 - 0.3 11.4 3.9 2 8.7 1.9 2.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) TMPIT PF07851.13 ETS74637.1 - 0.3 10.3 2.3 0.34 10.1 2.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein MRP-S28 PF10213.9 ETS74637.1 - 0.42 11.0 3.3 0.37 11.2 0.2 1.9 1 1 1 2 2 2 0 Mitochondrial ribosomal subunit protein Rho_Binding PF08912.11 ETS74637.1 - 0.43 11.4 10.6 0.27 12.1 5.7 2.2 1 1 1 2 2 2 0 Rho Binding DUF4407 PF14362.6 ETS74637.1 - 0.5 9.7 4.9 0.55 9.5 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mgr1 PF08602.10 ETS74637.1 - 0.72 8.6 4.3 0.83 8.4 4.3 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Fib_alpha PF08702.10 ETS74637.1 - 0.76 10.0 6.1 2.8 8.1 6.1 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF883 PF05957.13 ETS74637.1 - 1 10.0 3.8 6.7 7.4 0.9 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2205 PF10224.9 ETS74637.1 - 1.3 9.1 7.2 0.46 10.5 3.4 2.0 1 1 1 2 2 2 0 Short coiled-coil protein Ly49 PF08391.10 ETS74637.1 - 1.7 9.0 5.9 2.4 8.5 5.9 1.5 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region Spc24 PF08286.11 ETS74637.1 - 2.6 8.3 9.0 26 5.1 8.9 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 XhlA PF10779.9 ETS74637.1 - 2.9 8.2 7.8 1.4 9.2 2.2 2.2 1 1 1 2 2 2 0 Haemolysin XhlA TSC22 PF01166.18 ETS74637.1 - 3.6 8.0 6.9 0.9 9.9 1.0 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.21 ETS74637.1 - 3.8 7.7 13.1 17 5.6 5.3 3.4 2 1 1 3 3 2 0 bZIP transcription factor LMBR1 PF04791.16 ETS74637.1 - 7.6 5.3 4.8 8 5.2 4.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DHquinase_I PF01487.15 ETS74638.1 - 2.4e-44 152.3 0.0 3.6e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Fungal_trans PF04082.18 ETS74639.1 - 4.8e-27 94.7 0.0 8.7e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS74639.1 - 3.6e-05 23.8 15.7 6.5e-05 23.0 15.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS74639.1 - 0.16 10.7 0.3 0.53 9.0 0.1 2.0 2 0 0 2 2 2 0 Fungal specific transcription factor domain Clusterin PF01093.17 ETS74639.1 - 5.8 5.9 5.4 9.1 5.2 5.4 1.2 1 0 0 1 1 1 0 Clusterin NAD_binding_6 PF08030.12 ETS74640.1 - 4.4e-20 72.4 0.0 6.6e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 ETS74640.1 - 9.1e-15 54.9 11.0 9.1e-15 54.9 11.0 2.5 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ETS74640.1 - 1.4e-10 41.2 0.0 3e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 ETS74640.1 - 1.7e-05 25.4 0.0 0.0013 19.4 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Molydop_binding PF01568.21 ETS74640.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain DUF4405 PF14358.6 ETS74640.1 - 1.5 9.4 9.9 0.69 10.5 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) DHO_dh PF01180.21 ETS74641.1 - 1.1e-23 83.9 0.0 1.4e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 ETS74641.1 - 0.036 13.5 5.4 0.059 12.7 5.4 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase 3HCDH_N PF02737.18 ETS74642.1 - 8.4e-34 117.0 0.0 1.2e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ETS74642.1 - 1.9e-11 44.4 0.0 4.4e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ETS74642.1 - 7e-07 29.5 0.0 2.1e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ldl_recept_b PF00058.17 ETS74642.1 - 9.4e-05 22.8 0.1 9.8 6.8 0.0 5.4 5 1 0 5 5 5 1 Low-density lipoprotein receptor repeat class B NAD_Gly3P_dh_N PF01210.23 ETS74642.1 - 0.0005 20.1 0.0 0.00083 19.4 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 ETS74642.1 - 0.0016 17.8 0.1 0.007 15.7 0.1 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Arylesterase PF01731.20 ETS74642.1 - 0.0067 16.6 0.0 16 5.8 0.0 3.6 3 0 0 3 3 3 1 Arylesterase F420_oxidored PF03807.17 ETS74642.1 - 0.029 15.0 0.0 0.068 13.8 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 ETS74642.1 - 0.046 13.4 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sortase PF04203.13 ETS74642.1 - 0.053 13.3 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Sortase domain RRM_1 PF00076.22 ETS74643.1 - 7e-17 61.0 0.0 1e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ETS74643.1 - 0.058 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DivIC PF04977.15 ETS74643.1 - 0.24 11.2 4.3 0.4 10.5 4.3 1.2 1 0 0 1 1 1 0 Septum formation initiator HECT PF00632.25 ETS74644.1 - 1.1e-94 317.4 0.0 1.5e-94 317.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 ETS74644.1 - 1.3e-34 117.9 24.7 7e-13 48.4 6.3 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 ETS74644.1 - 2.1e-20 72.9 0.0 5.8e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain Alba PF01918.21 ETS74646.1 - 0.00016 21.4 1.2 0.0002 21.1 0.3 1.6 2 0 0 2 2 2 1 Alba tRNA-synt_His PF13393.6 ETS74646.1 - 0.023 14.0 1.3 0.035 13.4 1.3 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase DUF202 PF02656.15 ETS74647.1 - 8.7e-16 58.1 3.5 8.7e-16 58.1 3.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Bax1-I PF01027.20 ETS74647.1 - 0.0088 15.9 4.7 0.011 15.6 4.7 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Tctex-1 PF03645.13 ETS74648.1 - 3.1e-38 130.1 0.0 3.6e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family F-box-like PF12937.7 ETS74650.1 - 0.0058 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 F-box-like CCDC53 PF10152.9 ETS74650.1 - 0.82 10.1 4.0 0.55 10.6 2.1 1.7 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex CTP_transf_like PF01467.26 ETS74651.1 - 2.3e-29 102.4 0.0 4e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Fungal_trans PF04082.18 ETS74652.1 - 2.9e-10 39.6 0.2 5.9e-10 38.6 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 ETS74652.1 - 2.6e-06 27.6 9.4 0.0061 17.0 3.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS74652.1 - 0.0033 18.1 7.4 0.32 11.9 2.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger DUF3948 PF13134.6 ETS74652.1 - 0.019 14.6 1.2 0.051 13.3 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) CDK2AP PF09806.9 ETS74652.1 - 5.4 7.0 5.4 9.4 6.2 0.2 2.5 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein AMPK1_CBM PF16561.5 ETS74653.1 - 1.6e-20 73.1 1.2 3e-20 72.2 1.2 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 ETS74653.1 - 0.1 13.2 0.5 0.23 12.1 0.5 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Ion_trans PF00520.31 ETS74654.1 - 1.9e-09 37.2 0.3 2.3e-09 36.9 0.3 1.1 1 0 0 1 1 1 1 Ion transport protein bZIP_1 PF00170.21 ETS74654.1 - 0.00023 21.2 5.8 0.00065 19.7 0.6 2.3 2 0 0 2 2 2 1 bZIP transcription factor NEMO PF11577.8 ETS74654.1 - 0.027 14.5 0.5 0.047 13.7 0.5 1.4 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO bZIP_2 PF07716.15 ETS74654.1 - 0.041 14.0 1.4 0.041 14.0 1.4 1.9 2 0 0 2 2 2 0 Basic region leucine zipper Tnp_22_trimer PF17489.2 ETS74654.1 - 0.065 13.2 0.9 0.12 12.4 0.9 1.4 1 0 0 1 1 1 0 L1 transposable element trimerization domain Herpes_BLRF2 PF05812.12 ETS74654.1 - 0.074 13.2 0.4 0.12 12.5 0.4 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein APC_N_CC PF16689.5 ETS74654.1 - 0.12 12.5 1.0 0.2 11.7 1.0 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain CFEM PF05730.11 ETS74655.1 - 0.69 10.1 11.4 2.8 8.1 11.1 2.2 1 1 0 1 1 1 0 CFEM domain Oxidored_q6 PF01058.22 ETS74656.1 - 2.2e-22 79.3 0.0 3.2e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit MFS_1 PF07690.16 ETS74658.1 - 1e-32 113.4 56.5 3e-32 111.9 56.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS74658.1 - 1.7e-14 53.6 10.2 1.7e-14 53.6 10.2 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter GST_N PF02798.20 ETS74660.1 - 3.5e-14 52.9 0.1 7.5e-14 51.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ETS74660.1 - 4.1e-13 49.6 0.0 8.9e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ETS74660.1 - 8.9e-12 45.1 0.0 1.7e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ETS74660.1 - 2e-10 40.8 0.0 3.7e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ETS74660.1 - 3e-09 37.0 0.1 6.2e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ETS74660.1 - 1.1e-05 25.4 0.1 2.2e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ETS74660.1 - 0.0079 16.8 0.0 1.3 9.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ETS74660.1 - 0.14 12.9 0.0 0.25 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain NmrA PF05368.13 ETS74661.1 - 1.2e-27 97.0 1.0 1.4e-27 96.7 1.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS74661.1 - 2.5e-19 69.9 6.0 3e-19 69.6 4.9 1.7 1 1 1 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ETS74661.1 - 4.7e-05 23.6 2.3 0.00049 20.3 0.7 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ETS74661.1 - 5e-05 22.9 0.7 0.00011 21.7 0.4 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 ETS74661.1 - 0.0013 19.1 1.6 0.002 18.6 0.6 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 ETS74661.1 - 0.0078 16.0 0.6 0.013 15.2 0.2 1.5 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase adh_short PF00106.25 ETS74661.1 - 0.014 14.9 0.7 0.026 14.0 0.7 1.5 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 ETS74661.1 - 0.016 14.3 0.9 0.028 13.5 0.9 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ETS74661.1 - 0.085 12.2 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 ETS74661.1 - 0.11 12.7 1.5 0.3 11.2 1.5 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 ETS74661.1 - 0.13 12.9 2.1 0.3 11.7 2.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.19 ETS74661.1 - 0.21 10.9 0.1 0.21 10.9 0.1 2.3 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.15 ETS74661.1 - 1 9.2 5.7 0.71 9.7 3.3 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Glyco_hydro_2_N PF02837.18 ETS74662.1 - 3.5e-15 56.3 0.9 1.1e-14 54.8 0.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 ETS74662.1 - 7.8e-10 39.4 0.0 4.4e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 ETS74662.1 - 1.6e-06 27.5 0.1 5e-06 25.8 0.0 1.7 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain BetaGal_dom4_5 PF13364.6 ETS74662.1 - 0.00029 21.4 1.8 0.038 14.5 0.7 2.5 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain Big_7 PF17957.1 ETS74662.1 - 0.17 12.7 0.2 0.17 12.7 0.2 3.1 3 0 0 3 3 3 0 Bacterial Ig domain zf-RING_UBOX PF13445.6 ETS74663.1 - 6.1e-08 32.6 4.8 1.2e-07 31.6 1.1 2.4 1 1 1 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 ETS74663.1 - 8.5e-08 32.0 5.9 1.7e-07 31.0 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ETS74663.1 - 2e-06 27.6 4.8 4.4e-06 26.6 4.7 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ETS74663.1 - 4e-06 26.6 5.5 9e-05 22.2 1.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS74663.1 - 6.5e-06 25.9 7.0 1.5e-05 24.7 7.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ETS74663.1 - 6.7e-06 26.3 7.0 2e-05 24.9 7.1 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 ETS74663.1 - 0.00018 21.6 1.9 0.00018 21.6 1.9 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING DUF1416 PF07210.12 ETS74663.1 - 0.089 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) Prok-RING_4 PF14447.6 ETS74663.1 - 0.094 12.6 11.8 1.5 8.8 11.3 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Serglycin PF04360.12 ETS74663.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Serglycin zf-RING_10 PF16685.5 ETS74663.1 - 0.26 11.4 5.5 0.85 9.8 5.5 1.8 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 ETS74663.1 - 0.38 11.1 5.7 1.7 9.0 5.7 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain FYVE PF01363.21 ETS74663.1 - 1.6 8.9 6.0 25 5.1 6.5 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-Nse PF11789.8 ETS74663.1 - 3.8 7.4 10.5 0.24 11.3 5.2 1.7 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit Lipase_GDSL_2 PF13472.6 ETS74664.1 - 6.3e-10 39.7 1.2 8.2e-10 39.4 1.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS74664.1 - 3e-05 24.1 0.1 4.3e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FAD_binding_8 PF08022.12 ETS74665.1 - 2.2e-18 66.3 0.0 1.1e-17 64.1 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 ETS74665.1 - 7e-14 52.0 2.3 1.8e-13 50.7 2.3 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ETS74665.1 - 1.9e-11 44.4 0.0 5.5e-11 42.8 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain EF-hand_7 PF13499.6 ETS74665.1 - 0.0064 16.9 0.6 0.021 15.3 0.6 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 ETS74665.1 - 0.0072 15.8 0.1 0.02 14.4 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 ETS74665.1 - 0.037 14.0 0.1 0.1 12.6 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 ETS74665.1 - 0.096 12.2 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 EF hand GST_N_2 PF13409.6 ETS74666.1 - 1.1e-13 51.3 0.0 2.2e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ETS74666.1 - 1.4e-13 51.0 0.0 2.9e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ETS74666.1 - 1.6e-12 47.6 0.0 3.6e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS74666.1 - 0.00017 21.5 0.1 0.00033 20.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ETS74666.1 - 0.00095 19.7 0.0 0.0015 19.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 ETS74666.1 - 0.018 15.2 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin DUF3208 PF11482.8 ETS74666.1 - 0.047 14.0 0.0 0.085 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) RPE65 PF03055.15 ETS74667.1 - 4.9e-107 359.0 0.0 5.5e-107 358.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Hormone_3 PF00159.18 ETS74668.1 - 0.0082 16.2 3.5 0.22 11.6 0.2 2.7 2 0 0 2 2 2 2 Pancreatic hormone peptide Patatin PF01734.22 ETS74669.1 - 6.2e-21 75.5 0.0 1.2e-20 74.6 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase MMR_HSR1 PF01926.23 ETS74669.1 - 0.0021 18.1 0.0 0.0069 16.4 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 ETS74669.1 - 0.0024 17.2 0.0 0.0049 16.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.27 ETS74669.1 - 0.0027 18.2 0.0 0.0073 16.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter zf-B_box PF00643.24 ETS74669.1 - 0.0031 17.6 10.6 0.0053 16.9 4.7 2.6 2 0 0 2 2 2 1 B-box zinc finger AAA_22 PF13401.6 ETS74669.1 - 0.0069 16.7 0.0 0.048 13.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 ETS74669.1 - 0.0077 16.4 0.5 0.076 13.1 0.0 2.6 3 0 0 3 3 3 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 ETS74669.1 - 0.02 14.8 0.0 0.072 13.0 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 ETS74669.1 - 0.026 14.9 0.0 0.088 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 ETS74669.1 - 0.045 14.3 0.1 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ETS74669.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-C3HC4_3 PF13920.6 ETS74669.1 - 0.43 10.5 18.8 0.35 10.8 4.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GFO_IDH_MocA PF01408.22 ETS74670.1 - 2.2e-21 76.9 0.0 4.1e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ETS74670.1 - 2.6e-09 37.1 0.0 5.1e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 ETS74670.1 - 0.013 16.2 0.0 0.025 15.2 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain AAA_33 PF13671.6 ETS74670.1 - 0.1 12.8 0.0 0.28 11.3 0.0 1.7 1 1 1 2 2 2 0 AAA domain MIT PF04212.18 ETS74671.1 - 3.4e-15 55.9 0.8 7.6e-15 54.7 0.8 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Lipase_GDSL_2 PF13472.6 ETS74672.1 - 0.062 13.7 0.8 0.41 11.0 0.8 2.2 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Fungal_trans PF04082.18 ETS74673.1 - 1.7e-25 89.6 0.0 2.2e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldolase_II PF00596.21 ETS74674.1 - 4.1e-46 157.3 0.0 5.5e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ADH_zinc_N PF00107.26 ETS74675.1 - 7.4e-25 87.4 0.2 1.3e-24 86.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS74675.1 - 7.5e-18 65.9 0.5 1.4e-17 64.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS74675.1 - 5.3e-05 23.1 0.2 0.00053 19.8 0.0 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain FAD_binding_2 PF00890.24 ETS74676.1 - 1.2e-34 120.1 2.7 7.7e-30 104.3 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ETS74676.1 - 3.4e-08 33.1 0.1 1.1e-05 24.8 0.0 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS74676.1 - 7.8e-05 21.5 2.3 0.23 10.1 0.0 3.2 3 0 0 3 3 3 3 HI0933-like protein FAD_oxidored PF12831.7 ETS74676.1 - 0.00053 19.5 0.2 0.0013 18.1 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 ETS74676.1 - 0.0009 18.9 3.8 0.0009 18.9 3.8 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 ETS74676.1 - 0.00097 18.3 1.7 0.075 12.1 0.4 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 ETS74676.1 - 0.13 11.5 0.0 0.32 10.2 0.0 1.6 1 0 0 1 1 1 0 Thi4 family Amidohydro_2 PF04909.14 ETS74677.1 - 8.2e-22 78.3 0.6 1e-21 78.0 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase RSN1_7TM PF02714.15 ETS74679.1 - 1.2e-82 277.3 20.9 8.9e-82 274.5 17.2 2.3 2 0 0 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ETS74679.1 - 5.4e-45 152.9 3.2 1.6e-44 151.4 3.2 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 ETS74679.1 - 1.2e-24 86.3 0.4 2.6e-24 85.2 0.4 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 ETS74679.1 - 3.7e-15 56.6 0.6 7.1e-15 55.7 0.6 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Monooxygenase_B PF04744.12 ETS74679.1 - 0.092 11.6 0.2 0.21 10.4 0.2 1.5 1 0 0 1 1 1 0 Monooxygenase subunit B protein HEAT_2 PF13646.6 ETS74680.1 - 5.7e-21 74.7 23.9 6.1e-06 26.5 1.4 6.9 5 3 2 8 8 6 4 HEAT repeats NACHT PF05729.12 ETS74680.1 - 4.6e-15 55.9 0.0 2.5e-14 53.6 0.0 2.3 2 0 0 2 2 1 1 NACHT domain HEAT PF02985.22 ETS74680.1 - 6e-13 47.8 10.8 0.84 10.1 0.0 8.6 9 0 0 9 9 8 5 HEAT repeat NLRC4_HD2 PF17776.1 ETS74680.1 - 1.2e-06 29.1 0.1 6.7e-06 26.7 0.1 2.4 1 0 0 1 1 1 1 NLRC4 helical domain HD2 NB-ARC PF00931.22 ETS74680.1 - 2.7e-06 26.8 0.0 6.6e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Vac14_Fab1_bd PF12755.7 ETS74680.1 - 2.4e-05 24.9 3.6 0.45 11.1 0.1 5.7 5 2 1 6 6 5 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 ETS74680.1 - 0.00022 21.7 16.5 6.6 7.4 0.1 7.5 6 2 2 8 8 6 0 HEAT-like repeat AAA PF00004.29 ETS74680.1 - 0.00027 21.4 0.0 0.00083 19.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PGAP1 PF07819.13 ETS74680.1 - 0.00069 19.4 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein AAA_16 PF13191.6 ETS74680.1 - 0.00082 19.8 0.5 0.0047 17.3 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain Abhydrolase_6 PF12697.7 ETS74680.1 - 0.0019 18.9 0.0 0.0054 17.4 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.6 ETS74680.1 - 0.0023 18.2 0.0 0.011 16.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain DUF676 PF05057.14 ETS74680.1 - 0.0027 17.2 0.0 0.0061 16.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) NTPase_1 PF03266.15 ETS74680.1 - 0.005 16.8 0.0 0.019 14.9 0.0 2.1 1 0 0 1 1 1 1 NTPase DNA_alkylation PF08713.11 ETS74680.1 - 0.0067 16.2 2.1 0.033 13.9 1.1 2.7 1 1 1 2 2 2 1 DNA alkylation repair enzyme Cohesin_HEAT PF12765.7 ETS74680.1 - 0.0087 16.4 6.5 0.075 13.3 0.0 5.1 6 0 0 6 6 5 1 HEAT repeat associated with sister chromatid cohesion RNA_helicase PF00910.22 ETS74680.1 - 0.01 16.2 0.0 0.031 14.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Cnd1 PF12717.7 ETS74680.1 - 0.012 15.7 14.1 0.04 14.0 0.2 4.8 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 AAA_18 PF13238.6 ETS74680.1 - 0.017 15.7 0.0 0.069 13.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 ETS74680.1 - 0.036 13.8 0.0 1.5 8.5 0.0 2.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_17 PF13207.6 ETS74680.1 - 0.037 14.5 0.0 0.2 12.1 0.0 2.3 1 0 0 1 1 1 0 AAA domain Abhydrolase_9 PF10081.9 ETS74680.1 - 0.038 13.1 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Arm PF00514.23 ETS74680.1 - 0.064 13.3 6.6 4.2 7.6 0.0 5.8 6 1 1 7 7 7 0 Armadillo/beta-catenin-like repeat IclR PF01614.18 ETS74680.1 - 0.071 12.9 0.4 2.2 8.1 0.0 2.8 2 1 0 2 2 2 0 Bacterial transcriptional regulator AAA_24 PF13479.6 ETS74680.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Hydrolase_4 PF12146.8 ETS74680.1 - 0.15 11.3 0.0 0.41 9.9 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 IBN_N PF03810.19 ETS74680.1 - 0.23 11.4 10.8 1.2 9.1 0.1 6.2 7 1 0 7 7 7 0 Importin-beta N-terminal domain Vitellogenin_N PF01347.22 ETS74680.1 - 0.24 9.7 1.6 1.4 7.2 0.1 2.3 2 1 1 3 3 3 0 Lipoprotein amino terminal region Chitin_bind_1 PF00187.19 ETS74682.1 - 1e-47 160.3 278.0 2.5e-05 24.6 22.8 10.7 10 0 0 10 10 10 10 Chitin recognition protein Glyco_hydro_18 PF00704.28 ETS74683.1 - 1e-55 189.7 0.5 1.5e-55 189.1 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ETS74683.1 - 1.1e-06 28.9 10.7 1.1e-06 28.9 10.7 3.6 3 0 0 3 3 3 2 Chitin recognition protein adh_short_C2 PF13561.6 ETS74684.1 - 1.1e-53 182.2 2.8 1.4e-53 181.9 2.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS74684.1 - 2.7e-35 121.6 0.5 3.3e-35 121.3 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS74684.1 - 3.6e-15 56.4 0.1 5.2e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS74684.1 - 0.0011 18.5 0.1 0.0017 17.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS74684.1 - 0.032 13.6 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ETS74684.1 - 0.074 12.0 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_3_C PF01915.22 ETS74686.1 - 4.2e-25 88.9 0.0 4.8e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS74686.1 - 4.7e-16 59.1 0.0 6.8e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Sugar_tr PF00083.24 ETS74687.1 - 2.5e-79 267.3 18.8 3e-79 267.0 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS74687.1 - 8e-23 80.9 66.6 1.7e-19 70.0 32.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS74687.1 - 1.9e-07 30.0 22.5 0.00022 19.9 1.8 3.0 3 0 0 3 3 3 3 MFS/sugar transport protein Tyrosinase PF00264.20 ETS74688.1 - 9.8e-38 130.7 0.9 2.5e-37 129.3 0.6 1.8 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 ETS74688.1 - 6.8e-24 84.9 0.0 1.6e-23 83.7 0.0 1.6 2 0 0 2 2 2 1 Tyosinase C-terminal domain SAP130_C PF16014.5 ETS74688.1 - 0.44 9.6 9.5 0.72 8.9 9.5 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus GMC_oxred_N PF00732.19 ETS74689.1 - 9.2e-51 173.0 0.5 1.9e-49 168.7 0.5 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS74689.1 - 7.2e-33 114.1 0.0 1.7e-32 112.9 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 ETS74689.1 - 9.2e-06 25.8 0.2 3e-05 24.2 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ETS74689.1 - 1.1e-05 24.6 0.2 2e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ETS74689.1 - 1.8e-05 24.0 1.2 0.00068 18.8 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS74689.1 - 0.00036 19.9 0.0 0.0016 17.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS74689.1 - 0.0032 16.2 0.3 0.13 10.9 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 ETS74689.1 - 0.0038 16.5 0.0 0.0071 15.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS74689.1 - 0.0063 16.1 3.5 0.03 13.9 3.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS74689.1 - 0.023 14.0 0.9 2.8 7.1 0.4 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ETS74689.1 - 0.06 13.6 0.6 0.32 11.3 0.1 2.3 2 1 0 2 2 2 0 TrkA-N domain Thi4 PF01946.17 ETS74689.1 - 0.07 12.4 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 ETS74689.1 - 0.1 13.2 0.1 0.24 12.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS74689.1 - 0.16 12.0 0.2 0.33 10.9 0.2 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding p450 PF00067.22 ETS74690.1 - 3.7e-73 246.8 0.0 5e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4646 PF15496.6 ETS74691.1 - 0.026 15.1 0.1 0.056 14.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4646) Erf4 PF10256.9 ETS74691.1 - 0.041 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family AAT PF03417.16 ETS74692.1 - 0.085 12.5 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.6 ETS74693.1 - 6.3e-13 48.8 0.0 1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase IU_nuc_hydro PF01156.19 ETS74694.1 - 1.3e-46 159.6 0.0 1.5e-46 159.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Sugar_tr PF00083.24 ETS74695.1 - 1.5e-98 330.6 26.8 1.7e-98 330.4 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS74695.1 - 5.1e-19 68.4 33.6 4.2e-18 65.4 27.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 ETS74695.1 - 0.27 11.0 4.5 0.45 10.3 0.1 3.0 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) YrhK PF14145.6 ETS74695.1 - 0.33 10.9 0.1 0.33 10.9 0.1 3.6 4 0 0 4 4 4 0 YrhK-like protein Phage_holin_3_2 PF04550.12 ETS74695.1 - 5.8 7.5 7.8 0.89 10.1 1.7 2.9 2 1 1 3 3 3 0 Phage holin family 2 NOA36 PF06524.12 ETS74696.1 - 3.9 6.7 12.4 4.7 6.5 12.4 1.2 1 0 0 1 1 1 0 NOA36 protein CN_hydrolase PF00795.22 ETS74699.1 - 1.7e-68 230.8 0.2 1.5e-43 149.1 0.0 2.1 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase adh_short PF00106.25 ETS74700.1 - 7.4e-33 113.7 0.0 1.8e-32 112.4 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS74700.1 - 1e-27 97.2 0.0 2.3e-27 96.1 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS74700.1 - 1e-06 28.8 0.0 1.3e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.18 ETS74701.1 - 4.2e-05 22.7 0.2 6.9e-05 22.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS74701.1 - 9.3e-05 22.5 9.4 0.00016 21.7 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 7TM_GPCR_Str PF10326.9 ETS74701.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str Cep3 PF16846.5 ETS74701.1 - 0.17 10.3 0.0 0.25 9.8 0.0 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B MFS_1 PF07690.16 ETS74702.1 - 9.4e-25 87.3 31.7 9.4e-25 87.3 31.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_3 PF13738.6 ETS74703.1 - 9.6e-11 41.5 0.0 2.8e-10 39.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS74703.1 - 9.9e-08 31.5 0.0 1e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ETS74703.1 - 3.5e-07 29.8 0.0 8.7e-07 28.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ETS74703.1 - 3.8e-07 28.9 0.0 1.4e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ETS74703.1 - 0.00044 20.4 0.0 0.002 18.3 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ETS74703.1 - 0.0069 15.6 0.1 0.019 14.2 0.0 1.7 2 0 0 2 2 2 1 Thi4 family WD40 PF00400.32 ETS74705.1 - 4e-44 147.7 22.9 1.1e-08 35.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS74705.1 - 1.8e-08 34.6 0.8 0.13 12.6 0.0 4.5 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ETS74705.1 - 4.7e-06 25.5 6.6 0.055 12.1 0.1 4.3 1 1 3 4 4 4 4 Nucleoporin Nup120/160 WD40_like PF17005.5 ETS74705.1 - 0.0078 15.6 0.0 0.51 9.6 0.0 2.2 2 1 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 ETS74705.1 - 0.0078 15.2 0.1 7.1 5.5 0.0 3.9 1 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ETS74705.1 - 0.0098 14.5 0.1 2.5 6.5 0.1 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.12 ETS74705.1 - 0.015 15.2 0.5 20 5.3 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat VID27 PF08553.10 ETS74705.1 - 0.17 10.9 0.0 0.64 9.0 0.0 1.9 2 1 0 2 2 2 0 VID27 C-terminal WD40-like domain Bromo_TP PF07524.13 ETS74706.1 - 2.5e-16 59.4 0.0 5.6e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 ETS74706.1 - 1.4e-12 48.0 0.1 6e-12 45.9 0.1 2.2 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP_like PF17027.5 ETS74706.1 - 0.055 13.6 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Histone-fold protein TAF4 PF05236.14 ETS74706.1 - 0.37 10.5 8.4 0.29 10.8 6.4 1.8 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Pkinase_Tyr PF07714.17 ETS74707.1 - 9.3e-16 57.9 0.0 4.4e-14 52.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 ETS74707.1 - 2.1e-11 43.7 0.0 6.9e-11 42.0 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 ETS74707.1 - 3.1e-11 42.8 2.0 1.5e-07 31.1 0.4 3.3 1 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 ETS74707.1 - 5.9e-09 36.1 2.3 0.1 13.0 0.0 4.2 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) Kdo PF06293.14 ETS74707.1 - 1.5e-06 27.7 0.1 2.5e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ETS74707.1 - 0.00013 21.4 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like LRR_9 PF14580.6 ETS74707.1 - 0.0093 15.5 0.0 0.026 14.0 0.0 1.6 1 1 0 1 1 1 1 Leucine-rich repeat APH PF01636.23 ETS74707.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 ETS74707.1 - 0.052 13.1 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family LRR_1 PF00560.33 ETS74707.1 - 0.41 11.4 6.4 21 6.1 0.1 4.7 3 2 0 3 3 3 0 Leucine Rich Repeat 2OG-FeII_Oxy_2 PF13532.6 ETS74708.1 - 1.2e-28 100.6 0.1 2.5e-28 99.6 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 ETS74708.1 - 1.8e-24 86.9 0.0 8.8e-24 84.6 0.0 2.1 1 1 0 1 1 1 1 Isochorismatase family GST_C_3 PF14497.6 ETS74708.1 - 0.00019 21.6 0.0 0.0005 20.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ETS74708.1 - 0.0089 16.0 0.2 0.021 14.8 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ETS74708.1 - 0.071 13.3 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribosomal_L22 PF00237.19 ETS74710.1 - 8.1e-26 90.3 0.1 1.3e-25 89.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e GMC_oxred_C PF05199.13 ETS74711.1 - 1.1e-27 97.3 0.0 2.1e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 ETS74711.1 - 1.4e-25 90.3 0.0 1e-22 80.9 0.0 3.1 2 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 ETS74711.1 - 2.5e-05 23.7 0.0 0.00044 19.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS74711.1 - 0.0036 17.5 0.0 0.0099 16.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS74711.1 - 0.028 13.7 0.0 5.9 6.1 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS74711.1 - 0.066 11.9 0.3 0.11 11.2 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 ETS74711.1 - 0.081 12.0 2.0 0.17 10.9 1.4 1.8 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 ETS74711.1 - 0.22 10.8 1.4 0.41 9.9 1.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Peptidase_M28 PF04389.17 ETS74712.1 - 8.3e-37 126.8 0.2 1.2e-36 126.2 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ETS74712.1 - 6e-15 55.0 0.3 1.5e-14 53.7 0.3 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ETS74712.1 - 2.5e-05 24.1 0.1 6.6e-05 22.7 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Hpre_diP_synt_I PF07456.11 ETS74716.1 - 0.61 10.1 4.8 0.16 12.0 0.5 2.3 3 0 0 3 3 3 0 Heptaprenyl diphosphate synthase component I Pro_racemase PF05544.11 ETS74717.1 - 2.2e-122 408.2 0.1 2.5e-122 408.0 0.1 1.0 1 0 0 1 1 1 1 Proline racemase RL10P_insert PF17777.1 ETS74717.1 - 0.075 13.0 0.2 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Insertion domain in 60S ribosomal protein L10P Shikimate_DH PF01488.20 ETS74718.1 - 1.1e-06 28.8 0.1 4.5e-05 23.5 0.1 2.3 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.15 ETS74718.1 - 5.9e-06 25.4 0.0 0.00045 19.2 0.0 2.7 2 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Aa_trans PF01490.18 ETS74719.1 - 4.4e-43 147.5 36.3 5.3e-43 147.3 36.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 ETS74719.1 - 2.5e-06 26.6 25.7 2.5e-06 26.6 25.7 2.5 1 1 1 2 2 2 1 Amino acid permease Fungal_trans PF04082.18 ETS74720.1 - 2.5e-13 49.7 0.0 5.5e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lyase_1 PF00206.20 ETS74721.1 - 6.1e-90 301.8 0.0 8.5e-90 301.3 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 ETS74721.1 - 1.4e-22 80.2 0.0 3.4e-22 79.0 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal SHOCT PF09851.9 ETS74721.1 - 0.042 13.6 0.5 0.37 10.6 0.2 2.5 2 0 0 2 2 2 0 Short C-terminal domain ADH_zinc_N PF00107.26 ETS74722.1 - 2.1e-23 82.7 0.0 3.3e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ETS74722.1 - 5e-14 52.1 0.0 1.1e-13 51.0 0.0 1.6 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ETS74722.1 - 1.3e-10 42.4 0.0 3.7e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Ank_2 PF12796.7 ETS74723.1 - 6e-43 145.3 4.4 1.7e-08 34.9 0.2 8.2 5 2 2 8 8 8 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS74723.1 - 2.8e-32 107.1 7.1 0.0014 18.9 0.0 11.2 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.6 ETS74723.1 - 2.5e-29 101.3 5.4 4.5e-09 36.7 0.0 8.0 7 1 1 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS74723.1 - 3.1e-23 81.5 17.5 4.9e-07 29.9 0.6 9.9 8 3 4 12 12 12 5 Ankyrin repeats (many copies) Ank PF00023.30 ETS74723.1 - 2.4e-20 72.0 11.9 1.5e-05 25.2 0.0 9.4 11 0 0 11 11 10 4 Ankyrin repeat AAA_22 PF13401.6 ETS74723.1 - 2e-10 41.1 0.4 9.1e-10 38.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ETS74723.1 - 9.1e-05 22.4 0.0 0.00027 20.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 ETS74723.1 - 0.0036 16.7 0.1 0.0036 16.7 0.1 2.0 3 0 0 3 3 3 1 Fungal N-terminal domain of STAND proteins PIF1 PF05970.14 ETS74723.1 - 0.0072 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase SesA PF17107.5 ETS74723.1 - 0.0079 16.4 0.1 0.025 14.8 0.1 1.9 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_16 PF13191.6 ETS74723.1 - 0.014 15.8 0.0 0.052 13.9 0.0 2.0 2 0 0 2 2 1 0 AAA ATPase domain Kinesin PF00225.23 ETS74723.1 - 0.021 13.7 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain AAA_19 PF13245.6 ETS74723.1 - 0.022 15.1 0.0 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ETS74723.1 - 0.046 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 ETS74723.1 - 0.048 13.7 0.0 0.16 12.0 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Microtub_bd PF16796.5 ETS74723.1 - 0.083 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Microtubule binding AAA_7 PF12775.7 ETS74723.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 ETS74723.1 - 0.17 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AMP-binding PF00501.28 ETS74724.1 - 5.7e-53 180.0 0.0 7.2e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 ETS74724.1 - 2e-28 100.1 0.0 7e-28 98.3 0.0 1.9 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 ETS74724.1 - 2.4e-09 37.4 0.2 5.2e-09 36.3 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 ETS74724.1 - 3.3e-05 24.6 0.0 6.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS74724.1 - 0.0021 17.8 0.0 0.009 15.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS74724.1 - 0.027 13.7 0.0 0.073 12.3 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PE-PPE PF08237.11 ETS74724.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain ADH_N PF08240.12 ETS74725.1 - 7.5e-07 29.0 0.1 1.3e-05 25.0 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ETS74725.1 - 0.068 13.1 0.1 0.27 11.1 0.1 2.0 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 ETS74725.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TLD PF07534.16 ETS74726.1 - 2.2e-27 96.0 0.0 1.3e-26 93.5 0.0 2.0 1 1 0 1 1 1 1 TLD DUF1773 PF08593.10 ETS74726.1 - 5.7e-16 59.3 2.5 7.2e-16 59.0 0.5 2.3 2 0 0 2 2 2 1 Domain of unknown function HIG_1_N PF04588.13 ETS74727.1 - 2.5e-17 62.8 3.0 5.5e-17 61.7 3.0 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Isy1 PF06246.12 ETS74727.1 - 0.00078 19.1 3.8 0.0011 18.6 3.8 1.2 1 0 0 1 1 1 1 Isy1-like splicing family Nop25 PF09805.9 ETS74727.1 - 0.036 14.5 12.5 0.068 13.6 12.5 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) TAF4 PF05236.14 ETS74727.1 - 0.082 12.7 12.0 0.13 12.0 12.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family PIEZO PF15917.5 ETS74727.1 - 0.097 12.1 5.7 0.14 11.6 5.7 1.3 1 0 0 1 1 1 0 Piezo DUF1168 PF06658.12 ETS74727.1 - 0.68 9.8 15.1 1.2 9.0 15.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) PALP PF00291.25 ETS74728.1 - 1.2e-77 261.3 0.6 1.4e-77 261.0 0.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 ETS74728.1 - 3.7e-41 138.8 0.0 1.8e-19 69.3 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ribosomal_L36 PF00444.18 ETS74729.1 - 6.1e-05 23.1 3.9 0.00012 22.2 3.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L36 Acetyltransf_1 PF00583.25 ETS74730.1 - 1.6e-15 57.4 0.0 2e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS74730.1 - 1.6e-08 34.6 0.0 2.2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS74730.1 - 5.9e-08 33.0 0.0 9.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS74730.1 - 2.1e-05 24.4 0.0 4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ETS74730.1 - 4.7e-05 24.1 0.0 6.9e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2156 PF09924.9 ETS74730.1 - 0.00076 18.6 0.0 0.0023 17.0 0.0 1.8 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Acetyltransf_4 PF13420.7 ETS74730.1 - 0.0009 19.4 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ETS74730.1 - 0.0094 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 ETS74730.1 - 0.098 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HAD_2 PF13419.6 ETS74731.1 - 2.9e-07 30.8 0.0 4.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETS74731.1 - 0.0058 16.9 0.0 0.062 13.6 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ETS74731.1 - 0.0059 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Ldi PF18566.1 ETS74733.1 - 7e-120 400.3 0.3 8.6e-120 400.0 0.3 1.1 1 0 0 1 1 1 1 Linalool dehydratase/isomerase Arg_repressor_C PF02863.18 ETS74733.1 - 0.012 15.5 0.0 0.086 12.7 0.0 2.3 3 0 0 3 3 3 0 Arginine repressor, C-terminal domain Adipogenin PF15202.6 ETS74733.1 - 0.031 14.3 0.9 0.15 12.1 0.0 2.5 3 0 0 3 3 3 0 Adipogenin C166 PF17615.2 ETS74734.1 - 1.1e-27 97.1 0.3 1.3e-27 96.8 0.3 1.1 1 0 0 1 1 1 1 Family of unknown function HsbA PF12296.8 ETS74734.1 - 6.9e-05 23.3 2.1 6.9e-05 23.3 2.1 2.1 1 1 1 2 2 2 1 Hydrophobic surface binding protein A WXG100 PF06013.12 ETS74734.1 - 0.073 13.3 0.8 3.6 7.9 0.0 2.6 3 0 0 3 3 3 0 Proteins of 100 residues with WXG DUF5316 PF17247.2 ETS74736.1 - 0.15 12.1 0.2 0.42 10.7 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5316) Kelch_4 PF13418.6 ETS74737.1 - 4.1e-31 106.7 0.8 1.1e-14 54.1 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 ETS74737.1 - 1.6e-30 104.8 6.7 5.7e-07 29.7 0.0 6.6 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 ETS74737.1 - 6e-19 67.6 0.2 8.8e-05 22.6 0.0 6.3 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 ETS74737.1 - 1.4e-13 50.2 0.2 0.049 13.2 0.0 6.0 6 1 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 ETS74737.1 - 7.4e-11 41.8 0.4 0.4 10.7 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 ETS74737.1 - 1.5e-09 37.4 2.2 0.058 13.4 0.2 5.8 5 1 0 5 5 5 3 Kelch motif Fungal_trans PF04082.18 ETS74738.1 - 9.8e-12 44.5 0.3 5.9e-11 41.9 0.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Paxillin PF03535.13 ETS74738.1 - 0.51 10.2 4.0 0.51 10.2 0.9 2.5 2 1 1 3 3 3 0 Paxillin family Zn_clus PF00172.18 ETS74738.1 - 1 9.5 5.4 0.19 11.9 1.1 2.0 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_18 PF00704.28 ETS74742.1 - 1.1e-68 232.3 0.3 1.3e-68 232.0 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ETS74742.1 - 1.6e-13 50.9 17.5 2.9e-13 50.0 17.5 1.5 1 0 0 1 1 1 1 Chitin recognition protein PLAC8 PF04749.17 ETS74743.1 - 1e-18 68.1 0.9 1.4e-18 67.7 0.9 1.1 1 0 0 1 1 1 1 PLAC8 family ZZ PF00569.17 ETS74744.1 - 3.3e-10 39.6 6.9 6e-10 38.8 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 ETS74744.1 - 3.6e-09 35.5 8.0 0.00017 20.9 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 ETS74744.1 - 9.9e-08 32.3 3.3 0.0016 18.9 0.2 3.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 ETS74744.1 - 3.5e-06 26.5 5.8 0.0015 18.3 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 ETS74744.1 - 0.01 15.7 1.8 3.4 7.6 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain pair C1_2 PF03107.16 ETS74744.1 - 0.016 15.5 5.4 0.016 15.5 5.4 1.8 2 0 0 2 2 2 0 C1 domain EF-hand_4 PF12763.7 ETS74744.1 - 0.3 11.1 1.9 1.6 8.7 0.0 2.9 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 ETS74744.1 - 1.4 8.6 5.1 4.4 7.0 0.1 3.2 3 0 0 3 3 3 0 EF hand Hce2 PF14856.6 ETS74746.1 - 9.2e-18 64.4 0.0 1.3e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor p450 PF00067.22 ETS74747.1 - 3.2e-53 181.1 0.0 5e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M50B PF13398.6 ETS74748.1 - 1.6e-58 197.6 20.3 2.3e-58 197.2 20.3 1.2 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 ETS74748.1 - 0.011 15.0 0.9 0.02 14.1 0.1 1.8 2 0 0 2 2 2 0 Peptidase family M50 Peptidase_M41 PF01434.18 ETS74748.1 - 0.047 13.5 0.1 0.069 13.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M41 FAD_binding_3 PF01494.19 ETS74749.1 - 1.5e-47 162.5 0.0 1.9e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS74749.1 - 1.7e-06 27.9 0.0 0.0041 16.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS74749.1 - 7.5e-06 25.4 0.0 2.4e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS74749.1 - 2.1e-05 24.7 0.0 5.3e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ETS74749.1 - 7.1e-05 22.0 0.1 0.0031 16.6 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 ETS74749.1 - 0.00013 20.8 0.0 0.0013 17.6 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 ETS74749.1 - 0.00052 19.4 0.0 0.0098 15.2 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 ETS74749.1 - 0.0082 15.4 0.1 0.31 10.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS74749.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 ETS74749.1 - 0.015 15.9 0.0 1.8 9.2 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS74749.1 - 0.018 14.1 0.2 0.036 13.2 0.1 1.5 1 1 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 ETS74749.1 - 0.034 13.5 0.0 0.16 11.3 0.0 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 ETS74749.1 - 0.034 13.2 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.10 ETS74749.1 - 0.067 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase His_Phos_1 PF00300.22 ETS74749.1 - 0.12 12.0 0.0 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) 3HCDH_N PF02737.18 ETS74749.1 - 0.23 11.3 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 ETS74750.1 - 4.7e-14 52.1 21.7 7.9e-14 51.3 21.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 ETS74750.1 - 0.14 10.1 0.0 0.19 9.6 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HUN PF08729.10 ETS74750.1 - 0.16 12.0 1.0 0.4 10.7 1.0 1.6 1 0 0 1 1 1 0 HPC2 and ubinuclein domain NmrA PF05368.13 ETS74751.1 - 2e-32 112.6 0.0 2.4e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS74751.1 - 6.9e-17 61.9 0.0 1.7e-16 60.7 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 ETS74751.1 - 1.4e-06 28.0 0.0 7.5e-05 22.3 0.0 2.6 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ETS74751.1 - 0.00025 21.3 0.2 0.24 11.7 0.0 2.3 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 ETS74751.1 - 0.0019 17.7 0.0 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ETS74751.1 - 0.032 13.3 0.0 2.9 6.9 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 ETS74751.1 - 0.075 12.2 0.0 0.58 9.3 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein KR PF08659.10 ETS74751.1 - 0.12 12.2 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 KR domain Pollen_allerg_1 PF01357.21 ETS74752.1 - 0.047 13.7 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Pollen allergen Sdh5 PF03937.16 ETS74752.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase DUF3844 PF12955.7 ETS74753.1 - 7.8e-38 128.8 4.6 1.4e-37 128.0 4.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) UvrD_C_2 PF13538.6 ETS74753.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain KIP1 PF07765.12 ETS74754.1 - 2.6 8.2 5.4 0.66 10.1 0.6 2.4 3 0 0 3 3 3 0 KIP1-like protein FUSC PF04632.12 ETS74754.1 - 10 4.5 9.3 19 3.6 9.3 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family LSM PF01423.22 ETS74755.1 - 1.4e-21 76.0 0.5 1.5e-21 75.8 0.5 1.0 1 0 0 1 1 1 1 LSM domain Methyltransf_23 PF13489.6 ETS74756.1 - 4.9e-29 101.3 0.0 7.9e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS74756.1 - 1.2e-09 38.2 0.0 2.3e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS74756.1 - 5.2e-09 36.7 0.0 1.4e-08 35.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS74756.1 - 1.4e-07 32.1 0.0 1.3e-06 29.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS74756.1 - 3.9e-06 27.4 0.0 9.1e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 ETS74756.1 - 0.0022 17.5 0.0 0.0082 15.6 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase UPF0146 PF03686.13 ETS74756.1 - 0.005 16.7 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0146) MTS PF05175.14 ETS74756.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 ETS74756.1 - 0.016 14.9 0.0 0.032 14.0 0.0 1.5 1 1 0 1 1 1 0 Lysine methyltransferase DUF4959 PF16323.5 ETS74756.1 - 0.089 13.1 0.1 6.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4959) PrmA PF06325.13 ETS74756.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 ETS74756.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ASTN_2_hairpin PF18577.1 ETS74757.1 - 0.13 12.4 1.6 0.7 10.1 0.1 2.3 2 0 0 2 2 2 0 Astrotactin-2 C-terminal beta-hairpin domain UPF0547 PF10571.9 ETS74757.1 - 0.23 11.6 2.9 0.44 10.7 2.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 HET PF06985.11 ETS74758.1 - 7.5e-28 97.7 0.2 1.5e-27 96.7 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DNA_pol_phi PF04931.13 ETS74758.1 - 0.044 11.9 23.2 0.22 9.6 24.3 1.5 2 0 0 2 2 2 0 DNA polymerase phi CENP-B_dimeris PF09026.10 ETS74758.1 - 0.053 13.9 25.9 0.14 12.6 25.9 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 ETS74758.1 - 0.095 11.8 25.7 0.14 11.2 25.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 ETS74758.1 - 0.1 11.9 22.3 0.16 11.3 22.3 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 ETS74758.1 - 0.33 9.1 17.0 0.44 8.7 17.0 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 ETS74758.1 - 0.68 9.6 6.9 1.6 8.4 6.9 1.6 1 0 0 1 1 1 0 FAM176 family PPP4R2 PF09184.11 ETS74758.1 - 0.85 9.2 13.7 1.3 8.6 13.7 1.2 1 0 0 1 1 1 0 PPP4R2 Sporozoite_P67 PF05642.11 ETS74758.1 - 1.3 7.0 10.6 2.1 6.3 10.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_3_Rpc31 PF11705.8 ETS74758.1 - 1.6 8.9 21.0 2.6 8.2 21.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CobT PF06213.12 ETS74758.1 - 2 7.7 17.1 3.3 7.0 17.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 ETS74758.1 - 3.2 5.9 15.6 4.7 5.4 15.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 ETS74758.1 - 3.2 7.1 18.9 4.6 6.6 18.9 1.1 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 ETS74758.1 - 3.3 6.0 14.6 4.7 5.5 14.6 1.1 1 0 0 1 1 1 0 Mpp10 protein RXT2_N PF08595.11 ETS74758.1 - 3.4 7.7 11.5 6.6 6.8 11.5 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 ETS74758.1 - 4.4 7.0 21.6 7.6 6.2 21.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PI3K_1B_p101 PF10486.9 ETS74758.1 - 4.8 4.8 9.2 6.9 4.3 9.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pox_Ag35 PF03286.14 ETS74758.1 - 5.6 6.7 10.3 11 5.8 10.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sigma70_ner PF04546.13 ETS74758.1 - 9.9 6.0 16.7 17 5.2 16.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region NmrA PF05368.13 ETS74759.1 - 1.6e-30 106.4 0.0 2.1e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS74759.1 - 1.2e-15 57.9 0.0 3e-15 56.6 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ETS74759.1 - 0.00031 21.0 0.0 0.00065 20.0 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ETS74759.1 - 0.0061 16.0 0.0 0.49 9.8 0.0 2.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 ETS74760.1 - 1.8e-38 131.7 0.0 2.4e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS74760.1 - 2.5e-11 43.4 0.0 5.1e-11 42.4 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain TrkA_N PF02254.18 ETS74760.1 - 0.012 15.8 1.0 0.81 10.0 0.0 2.8 3 0 0 3 3 3 0 TrkA-N domain Gp_dh_N PF00044.24 ETS74760.1 - 0.025 14.9 0.0 0.047 14.0 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ETS74760.1 - 0.075 13.6 0.5 0.35 11.5 0.5 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 ETS74760.1 - 0.11 13.3 0.4 0.72 10.7 0.4 2.1 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PhyH PF05721.13 ETS74761.1 - 6.6e-27 95.2 0.0 9.6e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Cucumo_coat PF00760.18 ETS74762.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Cucumovirus coat protein Glyco_hydro_7 PF00840.20 ETS74763.1 - 4.5e-189 628.7 17.7 5.1e-189 628.5 17.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Pec_lyase_C PF00544.19 ETS74765.1 - 1.2e-10 41.3 7.2 9.2e-10 38.4 5.8 2.4 2 1 0 2 2 2 1 Pectate lyase MFS_1 PF07690.16 ETS74766.1 - 6.3e-11 41.8 19.1 8.5e-11 41.4 19.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_28 PF00295.17 ETS74767.1 - 2.2e-39 135.5 4.3 1.2e-38 133.0 4.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Pro_isomerase PF00160.21 ETS74768.1 - 2.8e-49 167.4 0.3 3.1e-49 167.3 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 ETS74768.1 - 0.024 14.7 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain zf-RING_2 PF13639.6 ETS74769.1 - 6.7e-12 45.5 5.7 1e-11 44.9 5.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ETS74769.1 - 9.2e-08 31.8 5.5 1.5e-07 31.2 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ETS74769.1 - 3.9e-07 29.8 3.0 6.2e-07 29.2 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ETS74769.1 - 4.7e-07 29.4 0.6 7.8e-07 28.7 0.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 ETS74769.1 - 7.8e-06 25.8 3.1 1.2e-05 25.2 3.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ETS74769.1 - 8.1e-06 26.0 9.5 3.5e-05 24.0 9.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ETS74769.1 - 0.0017 18.3 1.4 0.0034 17.4 1.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ETS74769.1 - 0.0026 17.7 0.7 0.0026 17.7 0.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ETS74769.1 - 0.0032 17.3 2.1 0.0048 16.7 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 ETS74769.1 - 0.012 15.4 6.2 0.02 14.6 6.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 ETS74769.1 - 0.14 12.1 4.5 0.27 11.1 4.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 ETS74769.1 - 0.22 11.1 4.2 0.41 10.3 4.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 ETS74769.1 - 0.23 11.7 3.1 0.57 10.4 3.1 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 ETS74769.1 - 0.26 11.2 5.3 0.46 10.4 5.3 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 ETS74769.1 - 0.53 10.4 3.0 1.1 9.4 3.0 1.6 1 1 0 1 1 1 0 RING-variant domain PSK_trans_fac PF07704.11 ETS74769.1 - 1 10.2 5.4 0.28 12.0 1.2 2.3 2 0 0 2 2 1 0 Rv0623-like transcription factor OAD_gamma PF04277.13 ETS74769.1 - 1.2 9.8 0.0 1.2 9.8 0.0 4.4 5 1 0 5 5 4 0 Oxaloacetate decarboxylase, gamma chain zf-UDP PF14569.6 ETS74769.1 - 7.4 6.8 6.0 0.36 11.0 0.3 1.8 2 0 0 2 2 1 0 Zinc-binding RING-finger Prok-RING_1 PF14446.6 ETS74769.1 - 9.2 6.3 7.8 0.41 10.6 1.1 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF3752 PF12572.8 ETS74770.1 - 4.5e-45 153.9 0.8 8.2e-45 153.0 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) Vps8 PF12816.7 ETS74771.1 - 1.5e-76 256.4 0.5 4.4e-75 251.6 0.0 2.5 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 ETS74771.1 - 3.6e-06 26.9 0.1 0.01 15.7 0.0 3.3 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-RING_5 PF14634.6 ETS74771.1 - 0.021 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 ETS74771.1 - 0.049 13.4 0.1 0.14 11.9 0.1 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 ETS74771.1 - 0.064 13.3 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 ETS74771.1 - 0.11 12.8 0.1 0.29 11.5 0.1 1.6 1 0 0 1 1 1 0 Ring finger domain LXG PF04740.12 ETS74771.1 - 0.15 11.7 0.5 0.76 9.5 0.5 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily zf-C3H2C3 PF17122.5 ETS74771.1 - 1.1 9.3 3.3 0.84 9.7 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger RhgB_N PF09284.10 ETS74772.1 - 8.6e-86 287.5 4.8 1.3e-85 287.0 4.8 1.3 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 ETS74772.1 - 1.4e-33 116.1 1.7 7.8e-33 113.7 0.8 2.3 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 ETS74772.1 - 2.8e-16 59.1 6.7 1e-15 57.3 6.7 2.0 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 ETS74772.1 - 0.0028 17.9 1.4 0.0028 17.9 1.4 2.4 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Cupin_5 PF06172.11 ETS74772.1 - 0.012 15.8 0.4 0.027 14.6 0.1 1.7 2 0 0 2 2 2 0 Cupin superfamily (DUF985) Alpha-amylase_C PF02806.18 ETS74772.1 - 0.069 13.6 1.3 0.64 10.5 0.2 2.8 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain Glyco_hydr_30_2 PF14587.6 ETS74773.1 - 5.1e-17 62.5 6.1 5.1e-17 62.5 6.1 1.7 2 1 0 2 2 2 1 O-Glycosyl hydrolase family 30 CLTH PF10607.9 ETS74774.1 - 4.3e-33 114.3 0.0 1.3e-32 112.7 0.0 1.8 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 ETS74774.1 - 4.2e-06 26.7 0.2 8.1e-06 25.8 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 ETS74774.1 - 0.00086 18.7 0.1 0.0013 18.1 0.1 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 ETS74774.1 - 0.0063 16.4 0.2 0.011 15.6 0.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 ETS74774.1 - 0.0092 16.3 0.3 0.016 15.5 0.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 ETS74774.1 - 0.022 14.9 0.1 0.055 13.6 0.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 ETS74774.1 - 0.026 14.3 0.4 0.05 13.5 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS74774.1 - 0.032 14.1 0.2 0.055 13.3 0.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ETS74774.1 - 0.069 13.0 0.4 0.13 12.2 0.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 ETS74774.1 - 0.11 12.4 0.4 0.21 11.5 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pellino PF04710.14 ETS74774.1 - 0.11 11.1 0.1 0.19 10.4 0.1 1.3 1 0 0 1 1 1 0 Pellino PG_binding_1 PF01471.18 ETS74775.1 - 0.0028 17.8 1.3 1.3 9.3 0.0 3.5 3 1 0 3 3 3 1 Putative peptidoglycan binding domain Myosin_tail_1 PF01576.19 ETS74775.1 - 0.0039 15.1 1.3 0.0039 15.1 1.3 1.5 1 1 0 1 1 1 1 Myosin tail ADIP PF11559.8 ETS74775.1 - 0.0062 16.6 1.0 0.015 15.3 0.1 2.1 1 1 0 2 2 2 1 Afadin- and alpha -actinin-Binding THOC7 PF05615.13 ETS74775.1 - 0.009 16.3 4.8 0.027 14.8 4.8 1.9 1 1 0 1 1 1 1 Tho complex subunit 7 XhlA PF10779.9 ETS74775.1 - 0.012 15.8 0.0 0.034 14.4 0.0 1.8 1 0 0 1 1 1 0 Haemolysin XhlA Tropomyosin_1 PF12718.7 ETS74775.1 - 0.048 13.8 3.9 0.045 13.9 1.3 2.1 2 0 0 2 2 2 0 Tropomyosin like FPP PF05911.11 ETS74775.1 - 0.13 10.4 0.6 0.18 9.9 0.6 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil PspA_IM30 PF04012.12 ETS74775.1 - 0.31 10.6 4.7 0.15 11.6 1.0 2.0 1 1 0 2 2 2 0 PspA/IM30 family BLOC1_2 PF10046.9 ETS74775.1 - 1.5 9.2 6.9 0.52 10.6 1.0 2.6 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TRAF_BIRC3_bd PF16673.5 ETS74775.1 - 1.6 8.6 5.8 0.31 10.8 1.0 2.3 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain HMMR_N PF15905.5 ETS74775.1 - 6.5 6.1 7.0 1.3 8.4 3.6 1.5 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal LETM1 PF07766.13 ETS74776.1 - 3.7e-102 341.3 0.1 3.7e-102 341.3 0.1 1.7 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 ETS74776.1 - 0.021 14.6 0.0 0.56 10.0 0.0 2.8 2 1 0 2 2 2 0 SAP domain DSBA PF01323.20 ETS74776.1 - 0.021 14.6 3.1 0.055 13.2 3.1 1.8 1 0 0 1 1 1 0 DSBA-like thioredoxin domain SelP_N PF04592.14 ETS74777.1 - 8.7 5.7 15.0 6.7 6.0 7.9 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region MAPEG PF01124.18 ETS74780.1 - 1.1e-13 51.2 4.4 1.7e-13 50.6 4.4 1.2 1 0 0 1 1 1 1 MAPEG family Caudal_act PF04731.12 ETS74780.1 - 0.18 12.2 0.1 0.21 11.9 0.1 1.1 1 0 0 1 1 1 0 Caudal like protein activation region TEA PF01285.18 ETS74782.1 - 2.3e-18 66.0 0.0 6.5e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 TEA/ATTS domain RRM_1 PF00076.22 ETS74783.1 - 1.6e-72 239.3 2.5 2.8e-20 71.9 0.1 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ETS74783.1 - 1.8e-08 34.4 0.0 0.001 19.1 0.0 5.2 5 0 0 5 5 5 1 RNA recognition motif RRM_occluded PF16842.5 ETS74783.1 - 6.4e-08 32.4 0.0 1.2 9.1 0.0 5.3 5 0 0 5 5 5 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 ETS74783.1 - 2.3e-07 30.7 0.5 0.082 12.9 0.1 3.8 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 ETS74783.1 - 5e-06 26.5 0.9 0.0052 16.8 0.0 4.9 5 1 0 5 5 5 1 Limkain b1 RRM_5 PF13893.6 ETS74783.1 - 7.4e-06 25.6 0.1 0.32 10.6 0.0 4.3 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 ETS74783.1 - 1.7e-05 25.1 5.6 1.6 8.9 0.2 5.0 3 2 1 4 4 4 3 Cytosolic domain of 10TM putative phosphate transporter RRM_Rrp7 PF17799.1 ETS74783.1 - 1.8e-05 24.6 3.6 2.2 8.1 0.0 5.4 6 0 0 6 6 5 2 Rrp7 RRM-like N-terminal domain RRM_3 PF08777.11 ETS74783.1 - 0.0002 21.3 1.3 3.6 7.7 0.0 5.1 4 1 1 5 5 5 1 RNA binding motif SET_assoc PF11767.8 ETS74783.1 - 0.00039 20.0 0.2 1.1 9.0 0.0 4.6 5 0 0 5 5 5 1 Histone lysine methyltransferase SET associated Smg4_UPF3 PF03467.15 ETS74783.1 - 0.0012 19.0 11.9 0.23 11.4 0.1 3.8 3 1 0 3 3 3 2 Smg-4/UPF3 family Phage_TAC_13 PF16459.5 ETS74783.1 - 0.012 16.0 0.1 4.3 7.9 0.0 3.6 4 0 0 4 4 4 0 Phage tail assembly chaperone, TAC Dynein_light PF01221.18 ETS74784.1 - 3.9e-40 136.1 0.6 4.4e-40 135.9 0.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Imm48 PF15574.6 ETS74784.1 - 0.057 13.2 0.1 0.085 12.6 0.1 1.3 1 1 0 1 1 1 0 Immunity protein 48 THAP PF05485.12 ETS74786.1 - 0.078 13.9 0.1 0.15 13.0 0.1 1.6 1 1 0 1 1 1 0 THAP domain Med2 PF11214.8 ETS74786.1 - 0.26 11.5 1.9 4.6 7.5 1.3 2.3 2 1 0 2 2 2 0 Mediator complex subunit 2 Methyltransf_16 PF10294.9 ETS74787.1 - 3.4e-21 75.7 0.0 6.1e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 ETS74787.1 - 0.0088 15.9 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain WD40 PF00400.32 ETS74788.1 - 1.9e-19 69.6 12.8 6.4e-05 23.6 0.1 10.1 10 0 0 10 10 10 5 WD domain, G-beta repeat Nucleoporin_N PF08801.11 ETS74788.1 - 0.0073 15.1 3.7 0.0076 15.0 0.1 2.8 2 1 0 2 2 2 1 Nup133 N terminal like Ricin_B_lectin PF00652.22 ETS74788.1 - 0.044 14.1 0.2 5 7.4 0.0 3.6 3 1 0 3 3 3 0 Ricin-type beta-trefoil lectin domain Glyco_hydro_47 PF01532.20 ETS74789.1 - 8.9e-113 377.6 0.0 1.2e-112 377.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Myb_DNA-binding PF00249.31 ETS74790.1 - 0.013 15.7 6.0 4.7 7.5 0.1 3.4 3 0 0 3 3 3 0 Myb-like DNA-binding domain Zn_clus PF00172.18 ETS74791.1 - 2.9e-06 27.3 9.8 2.9e-06 27.3 9.8 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.18 ETS74792.1 - 9.8e-14 51.3 0.3 2e-13 50.3 0.3 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein FA_desaturase PF00487.24 ETS74792.1 - 0.031 14.1 1.1 0.061 13.1 1.1 1.4 1 0 0 1 1 1 0 Fatty acid desaturase SUR7 PF06687.12 ETS74793.1 - 6.4e-36 124.0 14.2 8e-36 123.7 14.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family RE_Bsp6I PF09504.10 ETS74793.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Bsp6I restriction endonuclease RAP1 PF07218.11 ETS74793.1 - 1.3 7.2 8.8 1.7 6.8 8.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Metallophos PF00149.28 ETS74794.1 - 1.8e-34 120.1 0.1 2.6e-34 119.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ETS74794.1 - 2.1e-16 60.1 0.0 4e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain MFS_1 PF07690.16 ETS74795.1 - 1e-41 143.1 24.0 1.2e-41 142.9 24.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS74795.1 - 1.4e-12 47.2 8.0 1.4e-12 47.2 8.0 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter PTR2 PF00854.21 ETS74795.1 - 0.059 12.2 5.2 0.2 10.4 0.1 2.3 1 1 0 2 2 2 0 POT family Isochorismatase PF00857.20 ETS74796.1 - 3.5e-31 108.7 0.0 6.9e-31 107.8 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family UFD1 PF03152.14 ETS74796.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 HATPase_c PF02518.26 ETS74797.1 - 8.4e-22 77.8 0.1 1.9e-21 76.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ETS74797.1 - 1.5e-21 76.6 0.1 3.8e-21 75.3 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 ETS74797.1 - 2e-08 34.5 0.0 0.00015 22.0 0.0 3.3 3 0 0 3 3 3 2 PAS fold HisKA PF00512.25 ETS74797.1 - 3.9e-07 30.0 0.1 3.9e-07 30.0 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 ETS74797.1 - 4.3e-07 29.9 0.0 8.6e-06 25.7 0.0 3.1 3 1 0 3 3 3 1 PAS fold PAS_9 PF13426.7 ETS74797.1 - 1.3e-05 25.4 0.1 0.0003 21.0 0.0 3.2 3 0 0 3 3 3 1 PAS domain PAS_3 PF08447.12 ETS74797.1 - 0.00013 22.2 0.1 0.00034 20.8 0.1 1.8 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 ETS74797.1 - 0.00015 21.7 0.1 0.00085 19.3 0.1 2.4 3 0 0 3 3 3 1 PAS domain GAF_2 PF13185.6 ETS74797.1 - 0.03 14.6 0.0 0.96 9.7 0.0 3.0 3 0 0 3 3 2 0 GAF domain GAF_3 PF13492.6 ETS74797.1 - 0.087 13.2 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 GAF domain HD_2 PF12917.7 ETS74797.1 - 0.16 11.7 0.4 0.28 10.9 0.4 1.3 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Coagulase PF08764.10 ETS74797.1 - 0.16 12.1 0.2 0.28 11.4 0.2 1.3 1 0 0 1 1 1 0 Staphylococcus aureus coagulase Glyco_hydro_79C PF16862.5 ETS74799.1 - 5.7e-20 72.1 0.3 1.5e-19 70.8 0.3 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Aldedh PF00171.22 ETS74800.1 - 1.9e-165 550.9 3.0 2.1e-165 550.7 3.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tristanin_u2 PF16638.5 ETS74801.1 - 1.5 9.7 10.5 4 8.3 10.5 1.8 1 0 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers RRF PF01765.19 ETS74802.1 - 1.5e-33 116.0 2.7 2.2e-33 115.5 2.7 1.1 1 0 0 1 1 1 1 Ribosome recycling factor PX PF00787.24 ETS74803.1 - 6.2e-20 71.3 0.1 1.4e-19 70.1 0.1 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 ETS74803.1 - 3.7e-09 36.5 11.1 2.8e-05 23.8 1.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like AlkA_N PF06029.11 ETS74803.1 - 0.032 14.5 0.1 0.085 13.1 0.1 1.7 1 0 0 1 1 1 0 AlkA N-terminal domain Occludin_ELL PF07303.13 ETS74803.1 - 0.13 13.0 1.6 6.3 7.6 0.0 3.0 2 1 0 3 3 3 0 Occludin homology domain FlaC_arch PF05377.11 ETS74803.1 - 0.9 10.0 4.5 4.9 7.6 0.6 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Peptidase_S8 PF00082.22 ETS74804.1 - 2.9e-35 122.0 3.1 4.1e-35 121.5 3.1 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 ETS74804.1 - 9.4e-29 99.3 0.9 1.9e-28 98.3 0.9 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 ETS74804.1 - 0.078 13.8 0.1 0.18 12.6 0.1 1.6 1 0 0 1 1 1 0 Peptidase S8 pro-domain Glyco_transf_90 PF05686.12 ETS74806.1 - 7.4e-06 25.1 0.4 0.0014 17.6 0.0 3.3 3 1 0 3 3 3 2 Glycosyl transferase family 90 Acetyltransf_10 PF13673.7 ETS74807.1 - 2.4e-08 34.0 0.0 4e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS74807.1 - 8.3e-07 29.3 0.0 1.2e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS74807.1 - 9.7e-05 22.6 0.0 0.00022 21.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ETS74807.1 - 0.15 12.1 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HET PF06985.11 ETS74808.1 - 2.9e-35 121.8 0.5 5.8e-35 120.8 0.5 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 ETS74808.1 - 2.2e-05 25.0 0.1 0.28 11.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS74808.1 - 0.0029 18.2 0.1 1.4 9.6 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS74808.1 - 0.02 15.4 0.1 1.6e+02 3.4 0.0 4.6 4 0 0 4 4 4 0 Ankyrin repeat Glyco_hydro_18 PF00704.28 ETS74811.1 - 9.5e-73 245.6 0.1 1.4e-72 245.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ETS74811.1 - 1.3e-13 51.2 10.5 1.3e-13 51.2 10.5 4.0 4 0 0 4 4 4 1 Chitin recognition protein LysM PF01476.20 ETS74812.1 - 2e-16 59.7 2.1 0.0059 16.7 0.0 6.9 7 0 0 7 7 7 4 LysM domain HTH_Tnp_1 PF01527.20 ETS74812.1 - 0.0044 17.3 0.0 0.39 11.1 0.0 2.7 3 0 0 3 3 3 1 Transposase DUF2401 PF10287.9 ETS74813.1 - 4.5e-86 288.2 0.3 1e-85 287.0 0.3 1.6 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 ETS74813.1 - 2.3e-25 88.8 0.3 6.7e-25 87.3 0.0 2.0 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) MAGE_N PF12440.8 ETS74813.1 - 0.002 18.8 8.5 0.0053 17.4 8.5 1.7 1 0 0 1 1 1 1 Melanoma associated antigen family N terminal RE_XamI PF09572.10 ETS74813.1 - 0.036 13.7 0.1 0.059 13.0 0.1 1.3 1 0 0 1 1 1 0 XamI restriction endonuclease Plasmodium_Vir PF05795.11 ETS74813.1 - 0.21 11.0 4.1 0.29 10.5 4.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.9 ETS74813.1 - 0.84 8.1 8.5 1.1 7.8 8.5 1.1 1 0 0 1 1 1 0 Macoilin family SelP_N PF04592.14 ETS74813.1 - 5.7 6.3 11.1 0.17 11.2 4.8 1.6 2 0 0 2 2 2 0 Selenoprotein P, N terminal region NmrA PF05368.13 ETS74814.1 - 3.8e-62 209.9 0.0 4.6e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS74814.1 - 5e-17 62.4 0.0 6.7e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ETS74814.1 - 1.1e-06 27.9 0.1 1.5e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ETS74814.1 - 0.016 14.7 0.1 0.029 13.8 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ETS74814.1 - 0.019 15.2 0.1 0.027 14.7 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Peroxin-13_N PF04088.13 ETS74815.1 - 6.5e-52 175.7 0.0 8.8e-52 175.2 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 ETS74815.1 - 9.5e-11 41.2 0.0 1.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ETS74815.1 - 9.3e-08 31.6 0.0 1.5e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ETS74815.1 - 4.4e-05 23.2 0.0 7.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain IBN_N PF03810.19 ETS74816.1 - 6.2e-14 51.7 0.4 5e-13 48.8 0.5 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain OSCP PF00213.18 ETS74816.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Fungal_trans PF04082.18 ETS74817.1 - 0.00082 18.5 0.1 0.002 17.2 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pex2_Pex12 PF04757.14 ETS74818.1 - 5.2e-35 121.1 1.3 9.1e-35 120.3 1.3 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 ETS74818.1 - 0.00091 19.3 3.8 0.0018 18.4 3.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 ETS74818.1 - 0.02 14.9 1.6 0.063 13.3 1.5 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 ETS74818.1 - 1.4 9.3 5.2 6 7.3 1.8 2.3 2 0 0 2 2 2 0 Ring finger domain Cytochrom_B558a PF05038.13 ETS74819.1 - 0.0033 17.0 0.3 0.0092 15.6 0.2 1.8 1 1 0 1 1 1 1 Cytochrome Cytochrome b558 alpha-subunit Pribosyltran PF00156.27 ETS74820.1 - 3.2e-15 56.0 0.0 4.6e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ETS74820.1 - 0.0033 16.9 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PH_6 PF15406.6 ETS74821.1 - 4.1e-37 126.9 0.8 4.1e-37 126.9 0.8 3.1 2 1 1 3 3 3 1 Pleckstrin homology domain PH PF00169.29 ETS74821.1 - 0.00064 20.2 0.0 0.0018 18.8 0.0 1.8 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 ETS74821.1 - 0.13 12.2 0.2 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 PH domain DUF3332 PF11810.8 ETS74821.1 - 0.22 11.2 0.4 1.8 8.2 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3332) tRNA-synt_2 PF00152.20 ETS74823.1 - 5.6e-63 212.9 0.0 8.1e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ETS74823.1 - 2.5e-10 40.2 0.0 5.6e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ETS74823.1 - 6.5e-05 22.5 0.0 0.011 15.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) zf-Tim10_DDP PF02953.15 ETS74824.1 - 1.1e-18 66.6 1.4 1.3e-18 66.3 1.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger ADK PF00406.22 ETS74825.1 - 8.3e-38 129.8 0.1 1.6e-19 70.5 0.1 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 ETS74825.1 - 9.3e-15 54.3 0.0 1.7e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 ETS74825.1 - 4.1e-14 53.2 0.0 3.7e-10 40.4 0.0 2.6 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 ETS74825.1 - 7.7e-05 23.2 0.0 0.0076 16.8 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 ETS74825.1 - 0.0011 19.1 0.1 0.019 15.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 ETS74825.1 - 0.094 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DIOX_N PF14226.6 ETS74826.1 - 6.6e-29 101.1 0.0 1.1e-28 100.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS74826.1 - 2.6e-21 76.0 0.0 1.1e-20 74.0 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily zf-rbx1 PF12678.7 ETS74827.1 - 3.1 8.2 12.1 0.38 11.1 3.3 2.8 2 0 0 2 2 2 0 RING-H2 zinc finger domain ER_lumen_recept PF00810.18 ETS74828.1 - 9.4e-41 140.1 4.6 1.6e-40 139.4 4.6 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor Phtf-FEM1B_bdg PF12129.8 ETS74828.1 - 0.11 12.4 0.7 0.16 11.8 0.7 1.3 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor PhoLip_ATPase_C PF16212.5 ETS74828.1 - 0.31 10.8 12.1 1.1 9.0 12.1 1.8 1 1 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal Glyco_hydro_76 PF03663.14 ETS74829.1 - 4.1e-21 75.9 3.0 1.4e-12 47.9 0.5 3.3 3 1 0 3 3 3 2 Glycosyl hydrolase family 76 Prominin PF05478.11 ETS74830.1 - 0.056 11.4 1.1 0.08 10.9 1.1 1.1 1 0 0 1 1 1 0 Prominin DUF3440 PF11922.8 ETS74830.1 - 0.22 11.2 0.1 0.4 10.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Dehydratase_hem PF13816.6 ETS74832.1 - 8.1e-87 291.5 0.0 9.6e-87 291.3 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase Ribosomal_S17_N PF16205.5 ETS74834.1 - 3.4e-33 113.8 0.4 5.5e-33 113.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 ETS74834.1 - 7.1e-26 90.1 1.2 9.2e-26 89.7 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 Spc7_N PF15402.6 ETS74835.1 - 4.9e-204 680.4 97.5 6.5e-184 613.8 76.3 2.8 2 1 1 3 3 3 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 ETS74835.1 - 6.5e-125 416.1 9.5 6.5e-125 416.1 9.5 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 ETS74835.1 - 1.2e-17 63.7 0.0 2.4e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Spc7_C2 DUF4349 PF14257.6 ETS74835.1 - 0.00083 18.9 3.1 0.0025 17.3 3.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) DUF4795 PF16043.5 ETS74835.1 - 0.0091 15.6 10.6 0.0071 16.0 8.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4795) Baculo_PEP_C PF04513.12 ETS74835.1 - 0.075 13.1 0.9 0.21 11.6 0.9 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Not3 PF04065.15 ETS74835.1 - 2.8 7.3 17.1 0.22 10.9 3.3 2.9 2 1 1 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component Nucleoporin_FG PF13634.6 ETS74836.1 - 0.098 13.5 34.2 0.55 11.1 7.2 5.0 2 1 3 5 5 5 0 Nucleoporin FG repeat region Pkinase PF00069.25 ETS74837.1 - 8.7e-42 143.3 0.1 4.7e-22 78.6 0.2 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS74837.1 - 2.6e-14 53.1 0.4 1.4e-09 37.7 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 ETS74837.1 - 0.032 13.0 0.3 0.056 12.2 0.1 1.5 1 1 0 1 1 1 0 Fungal protein kinase Med26 PF08711.11 ETS74839.1 - 1.2e-11 44.4 0.0 2.9e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Brr6_like_C_C PF10104.9 ETS74840.1 - 3.5e-34 117.5 0.4 4.6e-34 117.1 0.4 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain PBP1_TM PF14812.6 ETS74840.1 - 0.004 17.5 0.3 0.004 17.5 0.3 2.4 3 0 0 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Fungal_trans PF04082.18 ETS74841.1 - 9.8e-24 83.8 0.2 1.8e-23 82.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS74841.1 - 1.5e-09 37.8 11.3 2.7e-09 37.0 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.15 ETS74842.1 - 9.9e-137 457.2 44.0 1.2e-136 456.9 44.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TPR_14 PF13428.6 ETS74842.1 - 0.038 14.8 0.0 3.8 8.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3425 PF11905.8 ETS74843.1 - 4.1e-14 52.6 0.0 1.2e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) adh_short PF00106.25 ETS74844.1 - 3.3e-25 88.7 0.0 4.5e-22 78.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS74844.1 - 9.7e-15 54.8 0.0 3.3e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS74844.1 - 1.2e-10 41.6 0.1 1.9e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 ETS74844.1 - 0.00023 20.7 0.1 0.00034 20.1 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ETS74844.1 - 0.001 18.6 0.1 0.0018 17.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SKG6 PF08693.10 ETS74845.1 - 0.015 14.7 0.1 0.037 13.4 0.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.6 ETS74845.1 - 0.38 10.7 10.3 8.6 6.3 10.3 2.3 1 1 0 1 1 1 0 TMEM154 protein family NUDE_C PF04880.13 ETS74845.1 - 4.4 7.8 12.1 7.1 7.1 12.1 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region FSA_C PF10479.9 ETS74845.1 - 6.5 4.8 11.4 8.3 4.4 11.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus MerC PF03203.14 ETS74846.1 - 0.013 16.0 0.6 0.035 14.5 0.6 1.8 1 0 0 1 1 1 0 MerC mercury resistance protein Abhydrolase_6 PF12697.7 ETS74847.1 - 1.4e-09 38.9 0.1 4.6e-09 37.2 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS74847.1 - 1.5e-08 34.3 0.6 6.4e-08 32.2 0.3 1.9 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS74847.1 - 2.7e-05 23.9 0.1 5e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 ETS74847.1 - 0.0016 18.1 0.2 0.0024 17.5 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 ETS74847.1 - 0.0018 18.2 0.1 0.0032 17.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS74847.1 - 0.016 14.7 0.1 0.05 13.1 0.2 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Cutinase PF01083.22 ETS74847.1 - 0.038 14.0 0.1 0.2 11.6 0.2 1.9 1 1 1 2 2 2 0 Cutinase Abhydrolase_5 PF12695.7 ETS74847.1 - 0.14 11.9 0.2 1.5 8.5 0.1 2.3 2 1 1 3 3 3 0 Alpha/beta hydrolase family FAD_binding_3 PF01494.19 ETS74849.1 - 1.1e-86 291.2 0.0 1.5e-86 290.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 ETS74849.1 - 6.2e-50 169.5 0.0 1.4e-49 168.3 0.0 1.7 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 ETS74849.1 - 2.7e-05 23.1 0.6 4.3e-05 22.4 0.6 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 ETS74849.1 - 0.00015 21.0 0.5 0.00025 20.3 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS74849.1 - 0.00088 18.6 0.5 0.0032 16.8 0.1 2.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS74849.1 - 0.0028 17.0 0.2 0.0046 16.3 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS74849.1 - 0.0031 17.7 0.0 0.0086 16.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ETS74849.1 - 0.0053 16.0 0.1 0.011 15.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 ETS74849.1 - 0.017 14.2 0.4 0.027 13.6 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ETS74849.1 - 0.019 14.3 0.2 0.033 13.5 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 ETS74849.1 - 0.057 12.8 0.2 0.094 12.0 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ETS74849.1 - 0.062 12.3 0.3 0.1 11.6 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Acetyltransf_1 PF00583.25 ETS74850.1 - 0.0028 17.9 0.1 0.0058 16.8 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family MFS_1 PF07690.16 ETS74851.1 - 3.4e-14 52.5 44.2 3.4e-14 52.5 44.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 ETS74851.1 - 1.6e-05 24.7 7.5 1.6e-05 24.7 7.5 3.0 2 2 0 2 2 2 1 Ion channel regulatory protein UNC-93 Fungal_trans PF04082.18 ETS74853.1 - 2e-08 33.6 0.0 3.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS74853.1 - 4.8e-06 26.6 8.4 1e-05 25.6 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HpcH_HpaI PF03328.14 ETS74854.1 - 4.6e-24 84.8 0.0 6e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family 2-Hacid_dh_C PF02826.19 ETS74855.1 - 1.3e-48 164.8 0.0 1.7e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS74855.1 - 7.7e-18 64.4 0.0 1e-17 64.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ETS74855.1 - 0.091 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 ETS74855.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.16 ETS74856.1 - 8.5e-34 117.0 36.6 8.5e-34 117.0 36.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1218 PF06749.12 ETS74856.1 - 5.8 7.5 9.4 1.3 9.6 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1218) Cyt-b5 PF00173.28 ETS74857.1 - 5.1e-15 55.4 0.0 7.5e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BioT2 PF15368.6 ETS74857.1 - 0.4 10.6 2.4 0.7 9.8 2.4 1.4 1 0 0 1 1 1 0 Spermatogenesis family BioT2 Apt1 PF10351.9 ETS74857.1 - 3.8 6.3 6.2 4 6.2 6.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.7 ETS74857.1 - 4.9 5.2 4.2 6.3 4.8 4.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NIBRIN_BRCT_II PF16508.5 ETS74858.1 - 1.1e-37 128.9 0.0 3.3e-37 127.5 0.0 1.8 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 ETS74858.1 - 1e-07 32.2 0.0 3.2e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 ETS74858.1 - 0.022 14.6 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain adh_short PF00106.25 ETS74861.1 - 6.4e-42 143.2 0.3 9.5e-42 142.7 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS74861.1 - 6.4e-31 107.7 0.4 9.7e-31 107.1 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS74861.1 - 5.4e-10 39.5 2.4 3.4e-08 33.6 2.4 2.2 1 1 0 1 1 1 1 KR domain UPF0146 PF03686.13 ETS74861.1 - 0.00011 22.0 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) Epimerase PF01370.21 ETS74861.1 - 0.0028 17.2 0.0 0.0053 16.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 ETS74861.1 - 0.0047 16.8 0.3 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein TrkA_N PF02254.18 ETS74861.1 - 0.0084 16.4 0.0 0.03 14.6 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain DUF1776 PF08643.10 ETS74861.1 - 0.029 13.7 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF3216 PF11505.8 ETS74861.1 - 0.044 14.0 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) UDPG_MGDP_dh_N PF03721.14 ETS74861.1 - 0.086 12.4 0.2 0.26 10.9 0.2 1.8 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Transketolase_C PF02780.20 ETS74861.1 - 0.11 12.4 0.2 0.61 10.0 0.0 2.2 2 1 0 2 2 2 0 Transketolase, C-terminal domain HET PF06985.11 ETS74863.1 - 4.8e-34 117.8 1.4 8.4e-34 117.0 1.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) A_deaminase PF00962.22 ETS74866.1 - 5.9e-23 81.7 0.0 1.2e-22 80.7 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase NmrA PF05368.13 ETS74867.1 - 2e-07 30.8 0.0 8.2e-07 28.8 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS74867.1 - 1e-06 28.8 0.0 3.6e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 ETS74867.1 - 0.0036 17.4 0.0 0.0058 16.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ETS74867.1 - 0.024 14.9 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ETS74867.1 - 0.024 14.9 0.0 0.039 14.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain PRD1_DD PF11087.8 ETS74867.1 - 0.077 12.7 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 PRD1 phage membrane DNA delivery LpxI_N PF17930.1 ETS74867.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 LpxI N-terminal domain NAD_binding_7 PF13241.6 ETS74867.1 - 0.15 12.6 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 ETS74867.1 - 0.19 12.3 0.0 0.33 11.6 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CTP_transf_like PF01467.26 ETS74868.1 - 6.5e-24 84.8 0.0 3.6e-21 75.9 0.0 3.1 3 0 0 3 3 3 2 Cytidylyltransferase-like PhyH PF05721.13 ETS74869.1 - 3e-56 191.0 0.0 4e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 ETS74869.1 - 0.041 14.3 0.0 0.081 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase RRM_1 PF00076.22 ETS74870.1 - 2.5e-34 116.9 0.1 3.7e-16 58.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ETS74870.1 - 1.7e-11 44.1 0.1 0.00021 21.3 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 ETS74870.1 - 6.9e-05 22.8 0.0 0.52 10.3 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 ETS74870.1 - 0.094 12.8 0.0 6.4 6.9 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif RabGAP-TBC PF00566.18 ETS74871.1 - 1.8e-49 168.3 0.0 2.8e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cullin_binding PF03556.15 ETS74871.1 - 0.32 11.4 1.9 0.79 10.2 1.2 2.0 2 0 0 2 2 2 0 Cullin binding Aminotran_4 PF01063.19 ETS74872.1 - 2e-26 93.2 0.0 2.6e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV PIR PF00399.19 ETS74877.1 - 0.00013 21.4 0.7 0.00013 21.4 0.7 2.4 2 0 0 2 2 2 1 Yeast PIR protein repeat GST_N_3 PF13417.6 ETS74878.1 - 2.6e-08 34.1 0.1 7.8e-08 32.6 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS74878.1 - 5e-06 26.4 0.1 1.2e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ETS74878.1 - 0.0034 17.6 0.0 0.0064 16.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ETS74878.1 - 0.016 15.4 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Aft1_HRA PF11786.8 ETS74879.1 - 4.6e-25 87.8 8.8 2.4e-24 85.5 8.8 2.3 1 0 0 1 1 1 1 Aft1 HRA domain Aft1_HRR PF11787.8 ETS74879.1 - 2.3e-24 86.3 4.9 2.3e-24 86.3 4.9 3.8 3 1 0 3 3 3 1 Aft1 HRR domain Aft1_OSA PF11785.8 ETS74879.1 - 1.4e-13 51.0 6.2 1.4e-13 51.0 6.2 3.2 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 ETS74879.1 - 7.4e-13 48.4 6.3 7.4e-13 48.4 6.3 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ETS74879.1 - 6.6e-06 26.1 6.8 1.2e-05 25.3 6.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ETS74879.1 - 0.0015 19.0 2.5 0.0034 17.9 2.5 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Phlebovirus_NSM PF07246.11 ETS74879.1 - 0.1 11.9 1.6 0.2 11.0 1.6 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF1319 PF07028.11 ETS74879.1 - 0.14 12.4 0.7 0.22 11.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Macoilin PF09726.9 ETS74879.1 - 0.76 8.3 4.6 0.9 8.0 4.6 1.1 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 ETS74879.1 - 7.1 6.5 22.1 0.067 13.2 13.2 1.8 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit MIS13 PF08202.11 ETS74880.1 - 3.9e-59 200.4 0.6 9.5e-59 199.1 0.6 1.6 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Rit1_C PF17184.4 ETS74880.1 - 0.18 11.2 0.7 0.71 9.3 0.2 1.9 2 0 0 2 2 2 0 Rit1 N-terminal domain Sdh5 PF03937.16 ETS74881.1 - 6e-25 87.0 0.2 1.8e-24 85.5 0.2 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase FAM117 PF15388.6 ETS74881.1 - 0.26 10.7 10.7 0.39 10.1 10.7 1.2 1 0 0 1 1 1 0 Protein Family FAM117 NAM-associated PF14303.6 ETS74881.1 - 1.4 9.6 5.5 2.2 9.0 5.5 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF515 PF04415.12 ETS74881.1 - 8.9 4.6 5.7 11 4.3 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) EMP24_GP25L PF01105.24 ETS74882.1 - 5.5e-41 140.5 0.0 6.3e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 ETS74882.1 - 0.013 13.7 1.3 0.018 13.3 1.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4407 PF14362.6 ETS74882.1 - 0.041 13.2 0.1 3.3 7.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) zf-U1 PF06220.12 ETS74883.1 - 6.3e-22 77.1 3.4 9.7e-22 76.5 3.4 1.3 1 0 0 1 1 1 1 U1 zinc finger Arginase PF00491.21 ETS74885.1 - 2.1e-90 303.0 0.0 2.7e-90 302.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 ETS74885.1 - 0.028 14.6 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain Atg14 PF10186.9 ETS74886.1 - 0.4 9.7 8.4 0.42 9.6 8.4 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Beta_helix PF13229.6 ETS74887.1 - 4.8e-09 36.3 17.5 5.2e-09 36.1 10.2 2.8 2 1 1 3 3 3 2 Right handed beta helix region Chondroitinas_B PF14592.6 ETS74887.1 - 2.7e-07 29.8 0.0 4.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Chondroitinase B DUF1565 PF07602.11 ETS74887.1 - 0.0092 15.3 0.6 0.0092 15.3 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1565) Gly-zipper_OmpA PF13436.6 ETS74887.1 - 4.9 7.0 8.2 20 5.1 1.2 2.7 2 0 0 2 2 2 0 Glycine-zipper domain stn_TNFRSF12A PF12191.8 ETS74888.1 - 0.99 9.6 5.2 0.56 10.4 2.4 2.0 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain SpoIIIAH PF12685.7 ETS74888.1 - 1.9 8.3 8.6 2.7 7.8 8.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein GFA PF04828.14 ETS74889.1 - 1.1e-23 83.4 0.0 1.5e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DNA_ligase_ZBD PF03119.16 ETS74889.1 - 0.022 14.8 0.5 0.063 13.3 0.5 1.8 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain DZR PF12773.7 ETS74889.1 - 0.065 13.3 3.2 0.5 10.4 0.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon NMD3 PF04981.13 ETS74889.1 - 0.12 11.8 0.7 0.53 9.7 0.1 1.9 1 1 0 2 2 2 0 NMD3 family zf-ribbon_3 PF13248.6 ETS74889.1 - 0.13 11.7 0.2 0.13 11.7 0.2 2.5 3 0 0 3 3 3 0 zinc-ribbon domain CpXC PF14353.6 ETS74889.1 - 0.14 12.2 0.4 8.6 6.4 0.0 2.2 1 1 1 2 2 2 0 CpXC protein Nudix_N_2 PF14803.6 ETS74889.1 - 0.35 10.8 0.0 0.35 10.8 0.0 2.6 3 0 0 3 3 3 0 Nudix N-terminal zf-RING_7 PF02591.15 ETS74889.1 - 1.1 9.5 4.8 4.1 7.7 0.1 3.0 3 0 0 3 3 3 0 C4-type zinc ribbon domain F5_F8_type_C PF00754.25 ETS74890.1 - 1.2e-24 86.9 3.8 4.4e-24 85.0 3.8 2.0 1 0 0 1 1 1 1 F5/8 type C domain DUF1929 PF09118.11 ETS74890.1 - 1.5e-24 86.1 0.5 3.8e-24 84.8 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 ETS74890.1 - 1.5e-09 37.8 9.5 0.00012 22.2 0.0 5.5 4 1 1 5 5 5 2 Kelch motif Glyoxal_oxid_N PF07250.11 ETS74890.1 - 7e-08 32.0 0.3 0.0046 16.2 0.4 2.4 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_1 PF01344.25 ETS74890.1 - 3.3e-07 29.8 5.8 0.005 16.4 1.3 5.1 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 ETS74890.1 - 5.5e-06 26.1 0.5 0.019 14.9 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 ETS74890.1 - 0.0013 18.7 7.0 0.088 12.8 0.0 5.2 4 0 0 4 4 4 1 Galactose oxidase, central domain DUF1471 PF07338.13 ETS74890.1 - 0.04 13.9 0.2 0.81 9.7 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) DUF1365 PF07103.11 ETS74891.1 - 1e-51 176.0 0.0 1.6e-51 175.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) MBF1 PF08523.10 ETS74892.1 - 8.1e-27 93.5 2.2 1.5e-26 92.6 2.2 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 ETS74892.1 - 4.1e-10 39.6 0.0 7.8e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ETS74892.1 - 0.0047 17.2 0.0 0.0095 16.3 0.0 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain Pyr_redox_dim PF02852.22 ETS74892.1 - 0.085 13.1 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain CDT1_C PF16679.5 ETS74893.1 - 4.8e-20 71.8 1.2 1.6e-19 70.2 0.0 2.5 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain Mem_trans PF03547.18 ETS74893.1 - 0.38 9.1 3.3 1.4 7.2 0.4 2.2 2 0 0 2 2 2 0 Membrane transport protein HET PF06985.11 ETS74894.1 - 1.8e-24 86.7 0.0 3.2e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 4HBT PF03061.22 ETS74896.1 - 9.9e-07 29.0 0.0 1.4e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 ETS74896.1 - 1.2e-06 29.0 0.0 1.5e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 ETS74896.1 - 3.2e-05 23.3 0.3 5e-05 22.7 0.3 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase PseudoU_synth_2 PF00849.22 ETS74897.1 - 1.5e-29 103.1 0.0 2.5e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 ETS74897.1 - 0.00071 19.2 0.0 0.002 17.8 0.0 1.8 1 0 0 1 1 1 1 S4 domain GFA PF04828.14 ETS74897.1 - 0.036 14.4 0.0 0.097 13.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Ub-Mut7C PF14451.6 ETS74897.1 - 0.083 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Mut7-C ubiquitin Auto_anti-p27 PF06677.12 ETS74897.1 - 0.095 12.9 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) PAS_4 PF08448.10 ETS74897.1 - 0.12 12.6 0.1 0.75 10.1 0.0 2.3 3 0 0 3 3 3 0 PAS fold DUF3425 PF11905.8 ETS74898.1 - 1.6e-19 70.1 0.1 2.7e-19 69.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 ETS74898.1 - 0.054 13.6 11.2 0.3 11.2 11.2 2.0 1 1 0 1 1 1 0 bZIP transcription factor DMPK_coil PF08826.10 ETS74898.1 - 0.095 12.8 3.5 2.9 8.1 0.1 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like HMW1C_N PF18071.1 ETS74898.1 - 0.17 11.6 0.3 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 HMW1C N-terminal Amidohydro_1 PF01979.20 ETS74899.1 - 9.7e-23 81.0 0.2 1.4e-18 67.3 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 ETS74899.1 - 8.8e-15 55.1 0.1 5.6e-12 45.9 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family SH3_16 PF18348.1 ETS74899.1 - 0.026 14.3 0.1 0.074 12.9 0.1 1.8 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain SPT_ssu-like PF11779.8 ETS74899.1 - 1.1 9.0 3.2 2.6 7.8 3.2 1.6 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like PCI PF01399.27 ETS74900.1 - 0.00076 20.0 0.1 0.0024 18.3 0.1 1.8 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 ETS74900.1 - 0.048 13.7 0.1 2 8.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TetR_C_24 PF17932.1 ETS74900.1 - 0.049 13.9 0.1 0.3 11.4 0.1 2.2 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TPR_6 PF13174.6 ETS74900.1 - 0.069 13.8 0.1 0.75 10.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ETS74900.1 - 0.1 12.8 0.4 1.2 9.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PaREP1 PF05942.11 ETS74900.1 - 0.14 12.1 1.1 0.42 10.6 1.1 1.8 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family Rep_fac-A_C PF08646.10 ETS74901.1 - 2.4e-58 196.0 3.5 2.2e-56 189.7 0.9 2.7 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 ETS74901.1 - 5.4e-37 125.6 3.0 4e-36 122.9 1.4 2.8 3 0 0 3 3 3 1 Replication protein A OB domain Rep-A_N PF04057.12 ETS74901.1 - 1.8e-20 72.8 0.0 3.9e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 ETS74901.1 - 5.9e-16 58.2 2.1 2.5e-11 43.4 0.0 4.6 4 1 0 4 4 4 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 ETS74901.1 - 4e-07 30.0 0.5 0.0013 18.5 0.3 2.8 2 1 0 2 2 2 2 Cell division control protein 24, OB domain 3 DUF5521 PF17659.1 ETS74901.1 - 0.011 13.6 0.2 0.063 11.1 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5521) zf-like PF04071.12 ETS74901.1 - 0.055 13.4 1.9 0.13 12.2 1.9 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain DLH PF01738.18 ETS74902.1 - 8.7e-22 77.7 0.1 1.3e-19 70.6 0.1 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 ETS74902.1 - 0.0037 17.2 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold ADH_zinc_N PF00107.26 ETS74903.1 - 2e-24 86.0 0.0 3.4e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS74903.1 - 6.5e-21 75.8 0.0 1.1e-20 75.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS74903.1 - 1.6e-09 37.6 0.0 2.8e-08 33.6 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF2828 PF11443.8 ETS74903.1 - 0.24 9.4 0.0 0.32 9.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Glyco_hydro_45 PF02015.16 ETS74905.1 - 5e-82 274.9 18.9 6.1e-82 274.6 18.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Hydantoinase_B PF02538.14 ETS74906.1 - 8e-220 730.6 0.1 1e-219 730.2 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 ETS74906.1 - 3.5e-103 344.9 0.7 3.5e-103 344.9 0.7 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ETS74906.1 - 2.1e-63 213.2 1.1 1.3e-61 207.4 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region SLAC1 PF03595.17 ETS74910.1 - 2.6e-80 270.1 39.9 3e-80 269.9 39.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Apt1 PF10351.9 ETS74910.1 - 8.7 5.1 8.9 12 4.7 8.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase PF00069.25 ETS74911.1 - 2.7e-73 246.6 0.0 6.3e-73 245.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS74911.1 - 1.2e-48 165.7 0.0 2.4e-48 164.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ETS74911.1 - 1.3e-05 24.1 0.1 3.5e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 ETS74911.1 - 0.003 16.9 0.0 0.066 12.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Mur_ligase_M PF08245.12 ETS74913.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Mur ligase middle domain Mur_ligase_C PF02875.21 ETS74913.1 - 0.12 12.6 0.0 0.41 10.9 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Pkinase PF00069.25 ETS74914.1 - 1.3e-72 244.4 0.0 1.8e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS74914.1 - 6.9e-38 130.4 0.0 1.1e-37 129.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 ETS74914.1 - 6.3e-19 68.6 1.2 2.5e-10 40.8 0.2 2.6 1 1 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 ETS74914.1 - 2.1e-14 53.3 0.2 5.5e-14 52.0 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 ETS74914.1 - 1e-05 25.0 0.0 3.5e-05 23.3 0.0 1.5 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 ETS74914.1 - 0.00099 18.8 0.2 0.0018 17.9 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 ETS74914.1 - 0.0032 16.5 0.1 0.006 15.6 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 ETS74914.1 - 0.0039 16.1 0.1 0.006 15.5 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 ETS74914.1 - 0.25 11.2 2.0 0.56 10.1 0.3 2.2 2 1 0 3 3 3 0 Phosphotransferase enzyme family DNA_pol_E_B PF04042.16 ETS74916.1 - 3.4e-64 216.1 0.0 5e-64 215.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B GCS PF03074.16 ETS74917.1 - 1.9e-177 590.1 0.0 2.3e-177 589.9 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GATA PF00320.27 ETS74918.1 - 4e-16 58.3 3.5 6.8e-16 57.6 3.5 1.4 1 0 0 1 1 1 1 GATA zinc finger MFS_1 PF07690.16 ETS74919.1 - 8.3e-09 34.8 37.4 2.3e-07 30.1 28.8 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Ost5 PF05251.12 ETS74919.1 - 0.058 13.7 5.8 0.91 9.8 3.7 3.4 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 DUF3824 PF12868.7 ETS74922.1 - 0.00021 22.0 9.1 0.00021 22.0 9.1 13.2 7 5 7 14 14 14 4 Domain of unknwon function (DUF3824) Metal_resist PF13801.6 ETS74922.1 - 0.013 15.7 0.4 0.013 15.7 0.4 4.9 4 1 1 5 5 5 0 Heavy-metal resistance Glyco_hydro_72 PF03198.14 ETS74923.1 - 9.5e-128 425.9 0.8 1.1e-127 425.6 0.8 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 ETS74923.1 - 8.7e-08 31.9 0.1 4.8e-07 29.5 0.1 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2713 PF10897.8 ETS74923.1 - 0.058 13.0 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) RTA1 PF04479.13 ETS74924.1 - 3.6e-70 235.8 9.9 3.6e-70 235.8 9.9 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF378 PF04070.12 ETS74924.1 - 0.018 14.9 2.5 0.018 14.9 2.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF378) HET PF06985.11 ETS74925.1 - 4.7e-25 88.6 0.0 1.2e-24 87.3 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Phage_TAC_2 PF06894.11 ETS74925.1 - 0.14 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G Cu-oxidase_3 PF07732.15 ETS74926.1 - 8.3e-38 129.1 3.3 8.3e-38 129.1 3.3 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ETS74926.1 - 2.6e-37 127.6 11.7 2.8e-37 127.5 0.4 3.6 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 ETS74926.1 - 1.1e-36 126.4 2.3 1.7e-35 122.5 0.8 2.5 2 0 0 2 2 2 1 Multicopper oxidase VSP PF03302.13 ETS74927.1 - 9.2e-05 21.5 1.8 9.2e-05 21.5 1.8 1.3 1 1 0 1 1 1 1 Giardia variant-specific surface protein Gram_pos_anchor PF00746.21 ETS74927.1 - 0.028 14.4 1.1 0.059 13.3 1.1 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF347 PF03988.12 ETS74927.1 - 0.034 14.3 0.2 0.079 13.2 0.2 1.7 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Sporozoite_P67 PF05642.11 ETS74927.1 - 0.037 12.1 7.0 0.044 11.9 7.0 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen SKG6 PF08693.10 ETS74927.1 - 0.089 12.2 0.0 0.24 10.8 0.0 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Anillin PF08174.11 ETS74927.1 - 0.17 12.3 2.8 0.38 11.2 2.7 1.6 1 1 1 2 2 2 0 Cell division protein anillin Podoplanin PF05808.11 ETS74927.1 - 0.29 11.2 4.3 0.42 10.7 4.0 1.4 1 1 0 1 1 1 0 Podoplanin PTP_tm PF18861.1 ETS74927.1 - 0.31 11.0 2.4 0.29 11.1 1.2 1.6 1 1 1 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J RAP1 PF07218.11 ETS74927.1 - 3.8 5.7 5.4 4.8 5.3 5.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) GMC_oxred_N PF00732.19 ETS74929.1 - 2e-62 211.2 0.0 2.7e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS74929.1 - 2.9e-32 112.2 0.0 5.3e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS74929.1 - 1.5e-08 34.2 4.4 0.00032 19.9 2.9 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 ETS74929.1 - 8.2e-05 21.8 0.9 0.00012 21.2 0.9 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 ETS74929.1 - 0.0001 21.7 1.2 0.00021 20.7 0.8 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS74929.1 - 0.00088 18.6 1.1 0.0011 18.3 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS74929.1 - 0.0042 16.7 6.8 0.095 12.3 6.7 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 ETS74929.1 - 0.0044 16.2 0.7 0.0071 15.5 0.2 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ETS74929.1 - 0.0045 17.2 2.1 0.01 16.0 1.5 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ETS74929.1 - 0.0086 16.6 0.0 0.025 15.1 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS74929.1 - 0.015 14.5 0.4 0.035 13.4 0.4 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 ETS74929.1 - 0.021 13.5 2.0 0.035 12.8 2.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 ETS74929.1 - 0.045 13.0 2.3 1.4 8.1 1.4 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ETS74929.1 - 0.18 11.4 0.6 0.37 10.4 0.6 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GDI PF00996.18 ETS74929.1 - 0.2 10.2 0.0 0.35 9.3 0.0 1.4 1 0 0 1 1 1 0 GDP dissociation inhibitor FAD_oxidored PF12831.7 ETS74929.1 - 1.4 8.2 7.9 1 8.6 5.6 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ETS74929.1 - 1.7 7.4 4.3 2.5 6.8 4.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 ETS74930.1 - 4.2e-13 49.3 1.1 0.0001 21.7 0.3 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 ETS74930.1 - 8.5e-05 22.3 0.0 0.0029 17.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS74930.1 - 0.00037 19.8 0.0 0.00056 19.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS74930.1 - 0.0007 20.1 0.1 0.0013 19.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS74930.1 - 0.0029 16.8 0.4 0.0051 15.9 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ETS74930.1 - 0.011 14.5 0.3 0.017 13.9 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 ETS74930.1 - 0.012 15.8 0.1 0.032 14.4 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS74930.1 - 0.024 13.9 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mvb12 PF09452.10 ETS74930.1 - 0.14 12.6 0.1 0.34 11.4 0.1 1.6 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 FAD_oxidored PF12831.7 ETS74930.1 - 0.16 11.2 0.1 0.26 10.6 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Uroplakin_II PF07353.12 ETS74932.1 - 0.12 11.8 0.4 0.22 11.0 0.4 1.4 1 0 0 1 1 1 0 Uroplakin II ketoacyl-synt PF00109.26 ETS74933.1 - 2.8e-67 227.0 0.3 5.2e-67 226.1 0.3 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ETS74933.1 - 8e-56 188.8 0.0 1.8e-55 187.6 0.0 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 ETS74933.1 - 2.7e-43 148.7 0.4 9.6e-43 146.9 0.4 1.9 1 1 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 ETS74933.1 - 3.3e-38 131.6 0.0 6.1e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 ETS74933.1 - 2.1e-35 121.3 0.0 6.3e-35 119.8 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ETS74933.1 - 1.7e-17 64.0 0.0 6.9e-17 62.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ETS74933.1 - 2.7e-14 53.6 0.0 8.3e-14 52.0 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 ETS74933.1 - 3.4e-11 43.7 0.0 1.8e-10 41.4 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS74933.1 - 4.7e-10 39.4 0.0 8.8e-09 35.3 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS74933.1 - 3.4e-09 37.2 0.0 1.1e-08 35.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS74933.1 - 3.6e-09 36.7 0.0 1.4e-08 34.8 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 ETS74933.1 - 9.7e-08 31.7 0.0 1.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 ETS74933.1 - 2.1e-06 28.0 0.0 4.9e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 ETS74933.1 - 0.0025 17.2 0.0 0.0062 15.9 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 ETS74933.1 - 0.0033 16.8 0.3 0.0085 15.5 0.3 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 ETS74933.1 - 0.075 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase ADH_N PF08240.12 ETS74933.1 - 0.095 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ETS74933.1 - 0.12 13.4 0.0 5.4 8.1 0.0 2.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase ACP_syn_III PF08545.10 ETS74933.1 - 0.21 11.4 0.8 0.6 10.0 0.8 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HET PF06985.11 ETS74934.1 - 2.7e-09 37.5 3.7 3.6e-09 37.1 0.9 2.6 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) Ead_Ea22 PF13935.6 ETS74934.1 - 6.2 7.5 5.9 18 6.0 4.4 2.4 1 1 1 2 2 2 0 Ead/Ea22-like protein Corona_6B_7B PF03262.13 ETS74936.1 - 0.094 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Coronavirus 6B/7B protein HET PF06985.11 ETS74937.1 - 2.3e-26 92.9 2.1 4.3e-26 92.0 2.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) OTT_1508_deam PF14441.6 ETS74938.1 - 3.1e-06 27.1 0.2 0.00029 20.8 0.2 2.5 1 1 0 1 1 1 1 OTT_1508-like deaminase Asp_Glu_race PF01177.22 ETS74941.1 - 3.3e-48 164.5 0.0 3.7e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Fructosamin_kin PF03881.14 ETS74942.1 - 1.5e-32 113.0 0.0 1.9e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 ETS74942.1 - 0.0024 17.8 0.0 0.0044 17.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DSHCT PF08148.12 ETS74943.1 - 1.2e-52 177.9 0.5 2.5e-52 176.9 0.5 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 ETS74943.1 - 6.8e-41 139.2 0.0 5.5e-39 133.1 0.0 2.4 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 ETS74943.1 - 2.3e-21 76.9 0.0 5.1e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 ETS74943.1 - 4.5e-18 65.6 0.0 1e-17 64.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS74943.1 - 2.3e-06 27.9 0.0 1.2e-05 25.6 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS74943.1 - 0.00011 22.2 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3516 PF12029.8 ETS74943.1 - 0.065 12.3 0.4 0.14 11.2 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3516) Swi3 PF07962.12 ETS74944.1 - 7.9e-31 105.9 0.4 1.5e-30 105.0 0.4 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 NADH-u_ox-rdase PF10785.9 ETS74945.1 - 6e-29 100.6 0.5 1e-28 99.8 0.5 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 ETS74945.1 - 2e-22 79.0 0.0 3e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Fungal_trans PF04082.18 ETS74946.1 - 2.2e-13 49.9 0.3 6e-13 48.4 0.3 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_transf_29 PF00777.18 ETS74946.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) FMN_dh PF01070.18 ETS74947.1 - 1.5e-80 270.9 0.2 1.2e-47 162.7 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 ETS74947.1 - 0.00053 19.1 0.2 0.0012 17.9 0.2 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ETS74947.1 - 0.0022 17.2 0.1 0.007 15.5 0.0 1.6 1 1 0 2 2 2 1 Conserved region in glutamate synthase Peptidase_M19 PF01244.21 ETS74947.1 - 0.012 14.8 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) NMO PF03060.15 ETS74947.1 - 0.022 14.2 0.1 0.1 11.9 0.1 1.9 1 1 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.21 ETS74947.1 - 0.043 13.0 0.2 7.8 5.6 0.0 2.4 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase CDP-OH_P_tran_2 PF08009.11 ETS74947.1 - 0.14 12.0 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase 2 Snf7 PF03357.21 ETS74948.1 - 1.1e-06 28.4 21.6 1.1e-06 28.4 21.6 1.7 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 ETS74948.1 - 0.0064 16.4 7.6 0.018 15.0 7.6 1.7 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway PFEMP PF03011.15 ETS74948.1 - 6.3 7.5 9.6 6.5 7.4 0.4 2.2 1 1 1 2 2 2 0 PFEMP DBL domain NTP_transf_9 PF04248.12 ETS74949.1 - 6.8e-33 112.4 0.0 8.9e-33 112.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Pro-rich_19 PF15455.6 ETS74949.1 - 0.029 13.5 0.5 0.032 13.4 0.5 1.0 1 0 0 1 1 1 0 Proline-rich 19 Sugar_tr PF00083.24 ETS74950.1 - 3.4e-79 266.8 27.2 3.8e-79 266.7 27.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS74950.1 - 6.6e-27 94.3 24.9 4.9e-25 88.2 24.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 ETS74951.1 - 9.3e-37 126.7 13.1 3.1e-19 69.1 8.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS74951.1 - 6.1e-07 28.7 14.7 0.00075 18.5 8.6 3.5 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 ETS74951.1 - 9.9e-05 21.4 19.1 0.00015 20.8 8.9 2.4 1 1 0 2 2 2 2 MFS_1 like family MFS_5 PF05631.14 ETS74951.1 - 0.0011 18.0 1.0 0.0011 18.0 1.0 1.6 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM OATP PF03137.20 ETS74951.1 - 0.0048 15.3 10.6 0.034 12.4 0.2 3.2 4 0 0 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family DUF2061 PF09834.9 ETS74951.1 - 0.19 12.3 0.1 0.19 12.3 0.1 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2061) MFS_3 PF05977.13 ETS74951.1 - 0.3 9.4 12.8 0.15 10.4 2.2 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector p450 PF00067.22 ETS74952.1 - 5.2e-55 187.0 0.0 6.6e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-RING_2 PF13639.6 ETS74954.1 - 1.9e-12 47.3 5.4 3e-12 46.7 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.22 ETS74954.1 - 2.8e-10 40.1 0.0 7.2e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.7 ETS74954.1 - 5.2e-09 36.3 2.3 1e-08 35.3 2.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ETS74954.1 - 8.8e-09 35.1 4.5 1.4e-08 34.4 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ETS74954.1 - 2.5e-08 33.7 3.5 4.2e-08 32.9 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ETS74954.1 - 6.4e-08 32.2 3.0 6.4e-08 32.2 3.0 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 ETS74954.1 - 7.9e-07 28.9 2.6 1.3e-06 28.3 2.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ETS74954.1 - 1.4e-05 24.9 3.0 2.2e-05 24.2 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS74954.1 - 4.3e-05 23.5 2.5 7.6e-05 22.7 0.6 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 ETS74954.1 - 0.0013 18.7 0.9 0.0024 17.9 0.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 ETS74954.1 - 0.011 15.5 3.0 0.024 14.5 3.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ETS74954.1 - 0.033 14.3 3.7 0.093 12.9 3.8 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 ETS74954.1 - 0.21 11.8 2.9 0.56 10.4 2.9 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 ETS74954.1 - 0.24 11.0 3.5 0.47 10.1 3.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 ETS74954.1 - 0.42 10.8 3.2 0.88 9.8 3.2 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 ETS74954.1 - 0.53 10.1 2.6 1.2 9.0 2.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2076 PF09849.9 ETS74954.1 - 0.57 10.2 0.0 0.57 10.2 0.0 4.5 4 1 0 6 6 5 0 Uncharacterized protein conserved in bacteria (DUF2076) zf-RING-like PF08746.11 ETS74954.1 - 0.68 10.3 3.4 1.2 9.5 3.4 1.4 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 ETS74954.1 - 0.88 9.5 2.8 1.6 8.6 2.8 1.5 1 0 0 1 1 1 0 PHD-finger p450 PF00067.22 ETS74955.1 - 3.1e-66 224.0 0.0 3.8e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 ETS74956.1 - 5.1e-125 417.9 19.2 5.9e-125 417.7 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS74956.1 - 4.9e-20 71.7 36.9 6.1e-19 68.1 31.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.12 ETS74956.1 - 0.26 11.5 2.0 1.1 9.5 0.0 2.9 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Rft-1 PF04506.13 ETS74957.1 - 1.1e-149 499.6 8.4 1.2e-149 499.3 8.4 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 ETS74957.1 - 0.0015 17.9 9.9 0.0015 17.9 9.9 3.4 2 2 1 3 3 3 1 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 ETS74957.1 - 0.005 16.1 0.0 0.005 16.1 0.0 3.5 3 1 0 3 3 3 2 Polysaccharide biosynthesis protein DEAD PF00270.29 ETS74958.1 - 1.1e-48 165.3 0.0 3.4e-48 163.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS74958.1 - 2.6e-33 114.7 0.1 2.3e-31 108.4 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS74958.1 - 3.2e-06 27.3 0.0 3.2e-06 27.3 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit TFIIF_alpha PF05793.12 ETS74958.1 - 0.001 17.8 40.2 0.0014 17.3 40.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CMS1 PF14617.6 ETS74958.1 - 0.023 14.0 0.0 0.023 14.0 0.0 4.2 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 ETS74958.1 - 0.041 12.7 0.0 0.5 9.1 0.0 2.5 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SOBP PF15279.6 ETS74958.1 - 0.37 11.3 11.2 0.59 10.7 11.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Borrelia_P83 PF05262.11 ETS74958.1 - 3.9 5.9 30.8 6 5.2 30.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein HORMA PF02301.18 ETS74959.1 - 2.3e-33 115.6 0.0 2.8e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 ETS74959.1 - 0.00078 19.5 0.3 0.0047 16.9 0.3 2.2 1 1 1 2 2 2 1 Autophagy-related protein 101 DUF2660 PF10859.8 ETS74959.1 - 0.019 15.4 0.1 0.041 14.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) bacHORMA_2 PF18173.1 ETS74959.1 - 0.026 14.4 0.1 0.075 12.9 0.1 1.7 1 1 0 1 1 1 0 Bacterial HORMA domain 2 Tox-MPTase3 PF15639.6 ETS74959.1 - 0.033 14.1 0.4 0.34 10.8 0.2 2.2 2 0 0 2 2 2 0 Metallopeptidase toxin 3 EptA_B_N PF08019.12 ETS74960.1 - 0.22 11.4 2.4 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB MHYT PF03707.16 ETS74960.1 - 2.5 8.3 5.7 0.52 10.5 0.5 2.4 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Glyco_hydro_2_C PF02836.17 ETS74961.1 - 5.4e-89 298.3 0.1 7.3e-89 297.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 ETS74961.1 - 1.2e-28 100.1 0.1 2.1e-28 99.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 ETS74961.1 - 5.4e-09 36.7 0.0 1.4e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 TPR_10 PF13374.6 ETS74961.1 - 0.08 12.8 0.3 0.31 11.0 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_42 PF02449.15 ETS74961.1 - 0.13 11.6 0.3 1.7 7.9 0.0 2.6 2 1 1 3 3 3 0 Beta-galactosidase DUF4434 PF14488.6 ETS74961.1 - 0.16 12.0 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Sugar_tr PF00083.24 ETS74962.1 - 2.7e-76 257.3 26.5 3e-76 257.1 26.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS74962.1 - 8.6e-21 74.2 31.3 8.6e-21 74.2 31.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS74962.1 - 5.9e-05 21.8 25.7 0.004 15.8 11.4 3.6 2 2 1 3 3 3 2 MFS/sugar transport protein DUF4713 PF15831.5 ETS74962.1 - 0.018 15.5 0.6 0.057 13.9 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) p450 PF00067.22 ETS74965.1 - 3.3e-58 197.5 0.0 4.3e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 ETS74966.1 - 1.4e-06 28.3 9.3 2.9e-06 27.3 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.7 ETS74967.1 - 1.8e-12 48.3 0.0 2.6e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS74967.1 - 2.6e-06 27.3 0.1 5.2e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS74967.1 - 0.0004 19.7 0.0 0.00047 19.5 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 ETS74967.1 - 0.018 14.9 0.1 0.048 13.5 0.1 1.7 1 1 0 1 1 1 0 Serine hydrolase Ank_2 PF12796.7 ETS74968.1 - 3.3e-32 110.9 4.0 1.8e-13 50.9 0.0 5.9 5 0 0 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS74968.1 - 3.1e-17 62.4 0.1 3.7e-06 27.1 0.0 6.1 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS74968.1 - 1.9e-16 58.4 0.1 0.0042 17.5 0.0 9.6 9 0 0 9 9 9 2 Ankyrin repeat Ank_4 PF13637.6 ETS74968.1 - 2.4e-15 56.7 0.2 2.8e-06 27.7 0.0 5.9 5 1 1 6 6 5 2 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 ETS74968.1 - 1.5e-11 44.0 0.0 3.4e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 ETS74968.1 - 1e-08 35.3 0.0 3e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Ank PF00023.30 ETS74968.1 - 2.9e-07 30.6 0.4 0.55 10.8 0.0 6.8 7 0 0 7 7 6 1 Ankyrin repeat AAA_16 PF13191.6 ETS74968.1 - 7.3e-05 23.2 0.2 0.00046 20.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS74968.1 - 0.037 14.3 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF4235 PF14019.6 ETS74968.1 - 0.082 13.0 0.1 5.1 7.3 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) MCCD1 PF15707.5 ETS74968.1 - 0.11 13.0 0.9 0.36 11.3 0.2 2.3 2 0 0 2 2 1 0 Mitochondrial coiled-coil domain protein 1 Bac_DnaA_C PF08299.11 ETS74968.1 - 0.19 11.8 0.5 1.6 8.8 0.0 2.7 3 0 0 3 3 3 0 Bacterial dnaA protein helix-turn-helix Flu_NS2 PF00601.19 ETS74968.1 - 0.34 11.2 4.6 12 6.2 0.1 4.4 4 0 0 4 4 4 0 Influenza non-structural protein (NS2) FAD_binding_4 PF01565.23 ETS74969.1 - 1.6e-19 70.0 4.9 3.6e-19 68.9 4.9 1.6 1 0 0 1 1 1 1 FAD binding domain Glyoxalase PF00903.25 ETS74970.1 - 4.7e-10 39.8 0.1 7e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAM124 PF15067.6 ETS74970.1 - 0.054 13.1 0.1 0.37 10.4 0.1 1.9 1 1 0 1 1 1 0 FAM124 family HET PF06985.11 ETS74971.1 - 8.1e-08 32.7 9.1 1.2e-05 25.7 2.5 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) GRIM-19 PF06212.12 ETS74971.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 GRIM-19 protein HET PF06985.11 ETS74972.1 - 1.3e-32 113.2 0.0 3.2e-32 111.9 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WHIM1 PF15612.6 ETS74972.1 - 0.16 11.6 0.0 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 1 HET PF06985.11 ETS74973.1 - 1.1e-20 74.5 0.1 5e-20 72.3 0.1 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SapB_1 PF05184.15 ETS74973.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Saposin-like type B, region 1 Peptidase_C39_2 PF13529.6 ETS74974.1 - 0.026 15.1 0.0 0.076 13.6 0.0 1.9 1 1 0 1 1 1 0 Peptidase_C39 like family Peptidase_C1 PF00112.23 ETS74974.1 - 0.068 13.2 0.4 0.6 10.2 0.4 2.4 1 1 0 1 1 1 0 Papain family cysteine protease FAD_binding_4 PF01565.23 ETS74975.1 - 9.3e-17 61.1 1.3 1.6e-16 60.3 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS74975.1 - 8.9e-10 38.5 0.1 1.6e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_5 PF00941.21 ETS74975.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase DUF2306 PF10067.9 ETS74978.1 - 2e-18 67.0 6.0 3.2e-18 66.3 6.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) VCBS PF13517.6 ETS74979.1 - 1.7e-29 102.2 51.1 4.4e-10 40.0 5.9 5.8 3 1 3 6 6 6 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 ETS74979.1 - 3.2e-23 83.0 9.2 6.1e-19 69.1 2.9 3.2 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS74979.1 - 3.9e-09 36.8 4.4 4.2e-09 36.7 0.2 2.6 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 ETS74979.1 - 3.6e-07 29.7 6.6 0.14 11.6 0.1 4.6 2 1 2 4 4 4 4 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 ETS74979.1 - 9e-05 22.5 29.2 0.099 12.8 0.5 6.4 5 0 0 5 5 5 4 FG-GAP repeat Dockerin_1 PF00404.18 ETS74979.1 - 0.00093 19.3 11.9 11 6.3 0.0 5.8 5 0 0 5 5 5 2 Dockerin type I domain Lipase_GDSL_3 PF14606.6 ETS74979.1 - 0.0024 18.0 0.0 0.0079 16.3 0.0 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family PliI PF16743.5 ETS74979.1 - 0.034 13.9 1.5 8.9 6.1 0.0 3.7 3 1 0 4 4 4 0 Periplasmic lysozyme inhibitor of I-type lysozyme HET PF06985.11 ETS74980.1 - 2.7e-39 134.9 1.2 3.7e-38 131.1 0.9 2.3 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF2236 PF09995.9 ETS74981.1 - 2.4e-09 37.8 0.2 5.1e-09 36.7 0.1 1.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) PIG-S PF10510.9 ETS74982.1 - 4.4e-171 570.2 4.8 5.1e-171 570.0 4.8 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein SAVED PF18145.1 ETS74982.1 - 0.078 12.8 0.6 3.8 7.3 0.1 2.4 1 1 1 2 2 2 0 SMODS-associated and fused to various effectors sensor domain PAN_3 PF08277.12 ETS74983.1 - 0.0084 15.9 0.3 0.034 13.9 0.3 2.0 1 0 0 1 1 1 1 PAN-like domain AMP-binding PF00501.28 ETS74984.1 - 7.9e-70 235.6 0.0 1e-69 235.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS74984.1 - 1.9e-08 35.1 0.2 5.8e-08 33.6 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Diphthamide_syn PF01866.17 ETS74985.1 - 4.7e-79 266.0 0.0 7e-79 265.4 0.0 1.3 1 0 0 1 1 1 1 Putative diphthamide synthesis protein GSH_synth_ATP PF03917.17 ETS74986.1 - 3.7e-132 440.6 0.0 4.2e-132 440.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 ETS74986.1 - 4.5e-29 100.9 0.1 1.4e-28 99.3 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic glutathione synthase G2F PF07474.12 ETS74986.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 G2F domain DAO PF01266.24 ETS74988.1 - 1.1e-28 100.9 0.0 1.9e-28 100.1 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS74988.1 - 8.8e-05 22.7 0.0 0.00049 20.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS74988.1 - 0.00029 20.2 0.0 0.036 13.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS74988.1 - 0.0022 17.2 0.1 0.06 12.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 ETS74988.1 - 0.0069 16.9 0.0 0.19 12.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS74988.1 - 0.008 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 ETS74988.1 - 0.06 13.8 0.0 0.25 11.8 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 ETS74988.1 - 0.18 11.3 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.6 ETS74989.1 - 3.6e-34 118.0 0.0 5.7e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 ETS74989.1 - 0.0019 17.8 0.0 5.5 6.5 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 ETS74989.1 - 0.0089 15.2 0.0 0.082 12.0 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Cu-oxidase_2 PF07731.14 ETS74991.1 - 1.1e-43 148.3 9.9 3.3e-43 146.7 1.5 2.6 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ETS74991.1 - 5.5e-39 132.9 3.3 5.5e-39 132.9 3.3 2.5 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 ETS74991.1 - 2.7e-35 121.8 3.1 3.8e-34 118.1 0.2 2.8 3 0 0 3 3 3 1 Multicopper oxidase DUF756 PF05506.12 ETS74991.1 - 0.027 15.4 0.5 0.83 10.6 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF756) MFS_1 PF07690.16 ETS74992.1 - 1.4e-38 132.8 41.4 6.1e-37 127.4 30.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS74992.1 - 0.0026 16.7 6.2 0.0026 16.7 6.2 2.2 2 0 0 2 2 2 2 MFS_1 like family RNase_H PF00075.24 ETS74993.1 - 2.9e-09 37.2 0.0 4.8e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 RNase H Asp PF00026.23 ETS74995.1 - 1.6e-63 215.0 9.5 2.9e-63 214.2 9.5 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS74995.1 - 4.5e-13 49.8 2.9 1.5e-12 48.1 2.9 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ETS74995.1 - 0.0011 19.6 0.5 10 6.9 0.4 3.6 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 ETS74995.1 - 0.037 14.6 0.0 34 5.1 0.0 3.9 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease Phage_holin_2_1 PF04971.12 ETS74995.1 - 0.097 12.7 0.5 0.58 10.2 0.5 2.4 1 0 0 1 1 1 0 Bacteriophage P21 holin S MFS_1 PF07690.16 ETS74996.1 - 3.6e-33 115.0 44.3 4.9e-32 111.2 44.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS74996.1 - 8.6e-16 57.5 16.9 1.3e-15 56.9 16.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS74996.1 - 5e-13 48.7 8.2 5e-13 48.7 8.2 3.0 1 1 1 3 3 3 2 Sugar (and other) transporter Erg28 PF03694.13 ETS74996.1 - 2.8 8.4 6.9 1 9.8 3.5 2.0 2 0 0 2 2 2 0 Erg28 like protein DUF423 PF04241.15 ETS74996.1 - 3.8 7.8 12.0 3 8.1 0.3 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF423) GMC_oxred_N PF00732.19 ETS74997.1 - 1.2e-55 189.0 0.0 1.6e-55 188.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS74997.1 - 1.7e-32 112.9 0.3 2.6e-32 112.3 0.3 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 ETS74997.1 - 5e-09 36.2 3.2 1.1e-08 35.0 2.1 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ETS74997.1 - 3.3e-05 23.1 0.3 0.00023 20.4 0.1 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ETS74997.1 - 0.00017 21.7 0.1 0.00086 19.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS74997.1 - 0.0047 16.2 0.1 0.032 13.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS74997.1 - 0.011 14.9 0.7 0.046 12.8 0.3 2.0 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 ETS74997.1 - 0.026 13.6 0.4 1.5 7.9 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 ETS74997.1 - 0.03 14.3 0.4 0.41 10.6 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 ETS74997.1 - 0.085 13.4 0.0 0.36 11.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 ETS74998.1 - 4.5e-12 46.5 0.0 1.1e-11 45.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS74998.1 - 7.9e-12 45.7 0.0 1.4e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS74998.1 - 4.5e-11 43.4 0.0 8.3e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS74998.1 - 2.6e-09 37.1 0.0 3.9e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS74998.1 - 8.1e-06 25.3 0.0 1.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ETS74998.1 - 3e-05 23.9 0.0 4.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 ETS74998.1 - 0.012 15.2 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) PrmA PF06325.13 ETS74998.1 - 0.032 13.6 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) adh_short PF00106.25 ETS74999.1 - 3.8e-17 62.4 0.0 5.5e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS74999.1 - 3.3e-13 49.7 0.0 4.2e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 ETS74999.1 - 0.0025 17.3 0.0 0.0049 16.3 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF3328 PF11807.8 ETS75000.1 - 1.2e-46 159.3 1.8 1.5e-46 158.9 1.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TrbC PF04956.13 ETS75001.1 - 0.71 10.1 4.7 12 6.2 0.3 2.7 2 0 0 2 2 2 0 TrbC/VIRB2 family FAD_binding_4 PF01565.23 ETS75002.1 - 4.3e-21 75.1 6.4 6.7e-21 74.5 6.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS75002.1 - 1.3e-06 28.4 0.1 3.3e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_3 PF01494.19 ETS75003.1 - 1.1e-17 64.3 0.2 1e-10 41.4 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 ETS75003.1 - 7.9e-06 25.7 0.9 0.0053 16.4 0.4 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ETS75003.1 - 0.00013 21.4 0.1 0.47 9.7 0.0 2.4 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 ETS75003.1 - 0.00017 20.9 0.1 0.00084 18.7 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS75003.1 - 0.00023 20.0 0.1 0.00032 19.5 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 ETS75003.1 - 0.00035 20.8 0.1 0.00072 19.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ETS75003.1 - 0.00082 19.9 0.2 0.0018 18.8 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS75003.1 - 0.0024 17.0 0.5 0.0048 16.0 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 ETS75003.1 - 0.0075 15.7 0.4 0.018 14.4 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS75003.1 - 0.04 13.2 0.1 0.079 12.2 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS75003.1 - 0.23 10.7 0.2 0.33 10.1 0.2 1.2 1 0 0 1 1 1 0 Thi4 family Ketoacyl-synt_C PF02801.22 ETS75004.1 - 2.8e-32 111.2 0.0 4e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 ETS75004.1 - 4.9e-24 85.3 0.3 8.7e-12 45.1 0.1 2.2 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Peptidase_C48 PF02902.19 ETS75006.1 - 2.5e-05 24.2 0.1 6.3e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF594 PF04578.13 ETS75006.1 - 0.081 12.5 0.2 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF594 MFS_1 PF07690.16 ETS75007.1 - 7.3e-31 107.4 80.3 5.6e-25 88.0 50.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS75007.1 - 4.6e-05 22.5 37.5 0.047 12.6 16.0 2.9 1 1 1 2 2 2 2 Sugar (and other) transporter TPR_12 PF13424.6 ETS75008.1 - 9.8e-15 54.6 25.4 1.6e-05 25.1 0.5 10.6 10 1 1 11 11 11 4 Tetratricopeptide repeat AAA_22 PF13401.6 ETS75008.1 - 3.3e-07 30.7 0.7 3.3e-06 27.4 0.1 3.0 2 0 0 2 2 2 1 AAA domain TPR_6 PF13174.6 ETS75008.1 - 0.00026 21.4 11.0 0.85 10.4 0.2 6.7 6 0 0 6 6 4 2 Tetratricopeptide repeat AAA_16 PF13191.6 ETS75008.1 - 0.00062 20.2 0.9 0.00062 20.2 0.9 3.5 5 0 0 5 5 5 1 AAA ATPase domain TPR_7 PF13176.6 ETS75008.1 - 0.00073 19.4 21.9 7.1 6.9 0.2 9.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 ETS75008.1 - 0.0035 17.4 11.6 1.2 9.6 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat NACHT PF05729.12 ETS75008.1 - 0.0075 16.2 0.1 0.034 14.0 0.1 2.2 1 0 0 1 1 1 1 NACHT domain TPR_19 PF14559.6 ETS75008.1 - 0.016 15.7 24.2 0.07 13.6 0.1 8.2 8 1 0 8 8 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 ETS75008.1 - 0.048 13.8 11.0 18 5.8 0.3 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Snf7 PF03357.21 ETS75008.1 - 0.1 12.2 4.5 0.046 13.3 0.7 2.4 2 0 0 2 2 2 0 Snf7 TPR_10 PF13374.6 ETS75008.1 - 1.3 9.0 31.4 1.3 9.0 0.0 10.6 12 0 0 12 12 12 0 Tetratricopeptide repeat TPR_14 PF13428.6 ETS75008.1 - 1.4 9.9 23.7 36 5.6 0.0 9.8 11 0 0 11 11 9 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 ETS75009.1 - 2e-57 193.9 0.1 4.3e-57 192.8 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ETS75009.1 - 1e-32 112.5 0.0 2.3e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 ETS75009.1 - 8.8e-32 109.0 0.0 1.7e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 ETS75009.1 - 5.4e-23 80.8 0.0 1.3e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ETS75009.1 - 5.1e-13 49.2 0.0 1.1e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 ETS75009.1 - 6.6e-07 29.2 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 ETS75009.1 - 0.067 13.3 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Condensation PF00668.20 ETS75009.1 - 0.15 10.7 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Condensation domain SDH_alpha PF03313.15 ETS75010.1 - 1.6e-98 329.6 2.4 2.3e-98 329.0 2.4 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 ETS75010.1 - 2.3e-53 180.7 0.2 8.3e-53 178.9 0.1 2.0 2 0 0 2 2 2 1 Serine dehydratase beta chain Sugar_tr PF00083.24 ETS75011.1 - 8.2e-75 252.4 23.4 9.6e-75 252.2 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS75011.1 - 8.1e-20 71.0 27.7 8.1e-20 71.0 27.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS75011.1 - 0.00012 21.1 4.1 0.00012 21.1 4.1 2.0 2 0 0 2 2 2 1 MFS_1 like family Phage_holin_2_4 PF16082.5 ETS75011.1 - 0.015 15.0 0.5 0.015 15.0 0.5 2.1 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like TraG_N PF07916.11 ETS75011.1 - 0.42 9.4 12.7 0.054 12.3 2.8 2.3 2 0 0 2 2 2 0 TraG-like protein, N-terminal region ADH_zinc_N_2 PF13602.6 ETS75012.1 - 8.6e-22 78.6 0.0 1.7e-21 77.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ETS75012.1 - 1.8e-19 70.0 0.0 4.6e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DFP PF04127.15 ETS75012.1 - 0.00014 21.7 0.2 0.00025 21.0 0.2 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein DUF2855 PF11017.8 ETS75012.1 - 0.00086 19.1 0.0 0.0021 17.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2855) DapB_N PF01113.20 ETS75012.1 - 0.0013 18.8 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 ETS75012.1 - 0.0028 17.1 0.5 0.0048 16.4 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 ETS75012.1 - 0.0056 16.2 0.1 0.0091 15.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ETS75012.1 - 0.017 14.2 0.0 0.023 13.8 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain THF_DHG_CYH_C PF02882.19 ETS75012.1 - 0.022 14.1 0.2 0.042 13.2 0.2 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PGM_PMM_II PF02879.16 ETS75012.1 - 0.032 14.9 0.0 0.06 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ELFV_dehydrog PF00208.21 ETS75012.1 - 0.036 13.8 0.6 0.053 13.2 0.6 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_N PF08240.12 ETS75012.1 - 0.059 13.3 0.0 0.43 10.5 0.0 2.3 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.6 ETS75012.1 - 0.065 13.1 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_3 PF03447.16 ETS75012.1 - 0.1 13.3 0.0 0.22 12.2 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 ETS75014.1 - 2.8e-53 181.1 4.1 2.8e-53 181.1 4.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS75014.1 - 2.7e-08 33.8 9.0 6.1e-08 32.7 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ctr PF04145.15 ETS75015.1 - 1e-31 110.6 4.3 1.5e-31 110.0 4.3 1.3 1 0 0 1 1 1 1 Ctr copper transporter family SRP_SPB PF02978.19 ETS75015.1 - 5.1 7.8 6.7 8.7 7.0 6.7 1.4 1 0 0 1 1 1 0 Signal peptide binding domain Hemerythrin PF01814.23 ETS75016.1 - 1.9e-05 25.3 0.2 2.7e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Sulfotransfer_4 PF17784.1 ETS75017.1 - 1.3e-52 178.8 0.1 1.5e-52 178.5 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ETS75017.1 - 0.0009 19.7 0.2 0.011 16.1 0.2 2.2 1 1 0 1 1 1 1 Sulfotransferase family Ank_2 PF12796.7 ETS75018.1 - 1e-68 227.9 1.3 3.8e-17 62.7 0.0 6.7 4 1 4 8 8 6 5 Ankyrin repeats (3 copies) Ank PF00023.30 ETS75018.1 - 2.4e-47 157.4 13.5 6e-06 26.5 0.0 9.2 7 2 2 9 9 8 7 Ankyrin repeat Ank_5 PF13857.6 ETS75018.1 - 2.2e-42 142.5 13.5 3.8e-08 33.4 0.0 8.5 3 1 6 9 9 9 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS75018.1 - 1.2e-40 137.3 11.5 3.7e-10 40.1 0.1 6.9 2 1 4 7 7 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS75018.1 - 1.5e-40 132.6 8.5 0.0001 22.4 0.0 10.5 10 0 0 10 10 10 7 Ankyrin repeat NACHT PF05729.12 ETS75018.1 - 3.4e-06 27.1 0.0 6.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ETS75018.1 - 1.1e-05 25.7 0.0 3.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS75018.1 - 1.4e-05 25.5 1.2 8.1e-05 23.1 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 ETS75018.1 - 0.0021 17.4 0.4 0.013 14.8 0.1 2.0 2 0 0 2 2 2 1 KAP family P-loop domain DUF4350 PF14258.6 ETS75018.1 - 0.0079 16.6 0.3 32 5.1 0.0 5.0 6 0 0 6 6 5 0 Domain of unknown function (DUF4350) AAA_18 PF13238.6 ETS75018.1 - 0.027 15.0 0.1 0.11 13.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ETS75018.1 - 0.038 14.1 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 ETS75018.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_30 PF13604.6 ETS75018.1 - 0.1 12.3 0.0 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ETS75018.1 - 0.11 13.0 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 ETS75018.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase HET PF06985.11 ETS75019.1 - 1.4e-24 87.1 0.0 3.3e-24 85.9 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GASA PF02704.14 ETS75019.1 - 0.042 14.0 1.0 0.17 12.1 1.0 2.0 1 0 0 1 1 1 0 Gibberellin regulated protein Toxin_TOLIP PF00087.21 ETS75021.1 - 0.13 12.5 0.5 0.29 11.4 0.5 1.6 1 0 0 1 1 1 0 Snake toxin and toxin-like protein EF1_GNE PF00736.19 ETS75023.1 - 5.3e-31 106.7 2.8 8e-31 106.1 2.8 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 ETS75023.1 - 3.5e-11 43.3 4.4 8.5e-11 42.1 4.4 1.7 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region Zip PF02535.22 ETS75024.1 - 2.9e-50 171.4 3.7 3.8e-50 171.0 3.7 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Glyco_hydro_18 PF00704.28 ETS75025.1 - 3.6e-46 158.3 0.2 5.7e-46 157.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.6 ETS75025.1 - 1e-19 70.7 1.7 2.9e-19 69.3 1.7 1.9 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Chitin_bind_1 PF00187.19 ETS75025.1 - 0.00011 22.6 8.6 0.00011 22.6 8.6 3.0 2 0 0 2 2 2 1 Chitin recognition protein LysM PF01476.20 ETS75025.1 - 0.08 13.0 0.0 4 7.6 0.0 2.7 2 0 0 2 2 2 0 LysM domain Acetyltransf_3 PF13302.7 ETS75026.1 - 6e-12 46.4 0.0 8.3e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS75026.1 - 0.011 15.9 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FAD_binding_4 PF01565.23 ETS75027.1 - 7.4e-25 87.3 0.0 1.2e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS75027.1 - 0.093 12.8 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 Berberine and berberine like adh_short PF00106.25 ETS75028.1 - 1.4e-09 37.7 0.0 1.4e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ETS75028.1 - 1.7e-05 24.8 0.1 2.4e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ETS75028.1 - 0.00012 21.7 0.2 0.00019 21.1 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 ETS75028.1 - 0.0039 16.6 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ETS75028.1 - 0.0061 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS75028.1 - 0.025 14.4 0.7 0.049 13.5 0.7 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Inj_translocase PF16928.5 ETS75028.1 - 0.059 12.8 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome Polysacc_synt_2 PF02719.15 ETS75028.1 - 0.16 11.1 0.0 0.29 10.2 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Chitin_synth_1 PF01644.17 ETS75029.1 - 2.5e-67 225.9 0.0 3.6e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 ETS75029.1 - 1.2e-25 90.1 0.4 1.2e-21 76.9 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 ETS75029.1 - 5.7e-24 83.9 0.2 2.1e-23 82.0 0.2 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 ETS75029.1 - 6.7e-09 35.9 5.2 2.2e-08 34.3 3.8 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 NMT_C PF02799.15 ETS75031.1 - 1.2e-85 286.3 0.2 1.9e-85 285.6 0.2 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 ETS75031.1 - 2.6e-74 248.4 1.4 2.9e-74 248.2 0.1 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 ETS75031.1 - 0.00077 19.5 0.2 0.017 15.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Cut8 PF08559.10 ETS75031.1 - 0.0031 17.2 1.8 0.008 15.8 1.8 1.6 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Ribosomal_S25 PF03297.15 ETS75031.1 - 0.25 11.6 6.6 0.15 12.3 4.1 2.0 2 0 0 2 2 2 0 S25 ribosomal protein Bac_luciferase PF00296.20 ETS75032.1 - 2.2e-67 227.7 0.1 2.7e-67 227.4 0.1 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Abhydrolase_1 PF00561.20 ETS75033.1 - 9.5e-15 54.9 0.0 2.2e-14 53.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS75033.1 - 1.3e-14 54.1 0.0 3.8e-14 52.5 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS75033.1 - 3.8e-14 53.8 0.0 5.2e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 ETS75033.1 - 1.6e-05 24.8 0.0 0.025 14.4 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 ETS75033.1 - 3.2e-05 23.5 0.1 0.014 14.8 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family UPF0227 PF05728.12 ETS75033.1 - 0.00012 22.1 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0227) Abhydrolase_4 PF08386.10 ETS75033.1 - 0.00031 20.8 0.0 0.0015 18.6 0.0 2.1 1 1 1 2 2 2 1 TAP-like protein DUF2048 PF09752.9 ETS75033.1 - 0.001 18.3 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Abhydrolase domain containing 18 DUF1100 PF06500.11 ETS75033.1 - 0.0036 16.1 0.0 0.0051 15.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Esterase_phd PF10503.9 ETS75033.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase BAAT_C PF08840.11 ETS75033.1 - 0.096 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 ETS75033.1 - 0.12 11.9 0.0 9 5.8 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family BRX_N PF13713.6 ETS75033.1 - 0.16 11.8 0.1 0.47 10.3 0.1 1.8 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain Methyltransf_2 PF00891.18 ETS75034.1 - 3e-24 85.5 0.0 4.1e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain NmrA PF05368.13 ETS75035.1 - 5.6e-18 65.4 0.0 7.3e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS75035.1 - 8.1e-09 35.6 1.2 9.3e-09 35.4 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 ETS75035.1 - 1.1e-06 28.3 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ETS75035.1 - 0.0091 16.3 0.2 0.038 14.2 0.1 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ETS75035.1 - 0.06 13.4 0.1 0.13 12.3 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TcA_RBD PF18518.1 ETS75035.1 - 0.062 13.6 0.0 0.17 12.2 0.0 1.6 2 0 0 2 2 2 0 TcA receptor binding domain FHA PF00498.26 ETS75035.1 - 0.17 12.3 0.0 0.3 11.5 0.0 1.3 1 0 0 1 1 1 0 FHA domain His_Phos_2 PF00328.22 ETS75036.1 - 1.3e-17 64.3 0.0 6.9e-17 61.9 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short_C2 PF13561.6 ETS75037.1 - 3.3e-36 125.0 0.1 4.2e-25 88.7 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS75037.1 - 5.7e-33 114.0 0.9 1.7e-32 112.5 0.9 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS75037.1 - 3.3e-05 23.9 0.6 7.8e-05 22.7 0.6 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS75037.1 - 0.00048 19.7 0.9 0.0023 17.5 0.1 2.3 2 1 1 3 3 3 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS75037.1 - 0.0049 15.9 0.1 0.0086 15.1 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_zinc_N PF00107.26 ETS75037.1 - 0.014 15.4 0.1 0.026 14.5 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Ubie_methyltran PF01209.18 ETS75037.1 - 0.026 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 ETS75037.1 - 0.027 15.2 0.0 0.084 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.18 ETS75037.1 - 0.036 14.3 0.1 0.064 13.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain GDP_Man_Dehyd PF16363.5 ETS75037.1 - 0.044 13.2 0.4 0.13 11.6 0.0 1.8 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_2 PF03446.15 ETS75037.1 - 0.071 13.3 0.3 0.33 11.1 0.1 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.15 ETS75037.1 - 0.083 12.0 0.1 0.16 11.1 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.10 ETS75037.1 - 0.092 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF2518 PF10726.9 ETS75037.1 - 0.1 12.3 0.4 3.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of function (DUF2518) Sacchrp_dh_NADP PF03435.18 ETS75037.1 - 0.14 12.4 0.3 0.25 11.6 0.3 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Cu_bind_like PF02298.17 ETS75038.1 - 0.024 14.6 0.3 0.057 13.4 0.3 1.6 1 1 0 1 1 1 0 Plastocyanin-like domain SGL PF08450.12 ETS75039.1 - 0.00038 20.1 1.4 0.0039 16.8 0.8 2.2 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 ETS75039.1 - 0.054 13.5 1.0 2.4 8.2 0.2 2.9 3 0 0 3 3 3 0 Beta-propeller repeat HMG-CoA_red PF00368.18 ETS75040.1 - 1.6e-137 458.4 3.9 2.1e-137 458.0 3.9 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 ETS75040.1 - 3.9e-44 150.3 0.5 8.5e-44 149.2 0.5 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 ETS75040.1 - 5.6e-14 52.2 5.2 3.9e-13 49.5 5.2 2.2 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 ETS75040.1 - 4.2e-08 31.8 0.5 4.2e-08 31.8 0.5 1.4 2 0 0 2 2 2 1 Patched family Isochorismatase PF00857.20 ETS75041.1 - 3.4e-26 92.5 0.0 5.8e-26 91.7 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family DUF3328 PF11807.8 ETS75044.1 - 1e-45 156.2 0.1 1.3e-45 155.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) SOG2 PF10428.9 ETS75046.1 - 2.3 7.3 10.2 2.2 7.4 10.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Alpha_GJ PF03229.13 ETS75046.1 - 3.4 8.3 5.4 4.5 7.9 5.4 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J RAP1 PF07218.11 ETS75046.1 - 7.7 4.7 7.7 6.4 4.9 7.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) GRDP-like PF07173.12 ETS75047.1 - 1.4e-16 61.4 2.5 1.7e-11 44.9 0.0 2.7 2 1 0 2 2 2 2 Glycine-rich domain-containing protein-like Herpes_UL32 PF06070.11 ETS75047.1 - 0.54 7.9 6.5 2.6 5.7 1.0 2.1 2 0 0 2 2 2 0 Herpesvirus large structural phosphoprotein UL32 Hva1_TUDOR PF11160.8 ETS75048.1 - 7e-18 64.5 1.0 7e-18 64.5 1.0 2.7 2 1 1 3 3 3 1 Hypervirulence associated proteins TUDOR domain LRIF1 PF15741.5 ETS75048.1 - 0.096 11.2 10.6 0.12 10.9 10.6 1.2 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Macoilin PF09726.9 ETS75048.1 - 0.45 9.0 15.7 0.49 8.9 15.7 1.0 1 0 0 1 1 1 0 Macoilin family TFIIF_alpha PF05793.12 ETS75048.1 - 1.1 7.8 49.7 1.3 7.5 49.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 ETS75048.1 - 3.7 6.8 46.4 4.5 6.5 46.4 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 ETS75048.1 - 8.8 5.6 48.0 12 5.2 48.0 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 ETS75048.1 - 9.5 4.3 45.0 11 4.1 45.0 1.0 1 0 0 1 1 1 0 Nop14-like family Hce2 PF14856.6 ETS75049.1 - 2.5e-14 53.4 0.0 3.3e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Hce2 PF14856.6 ETS75050.1 - 0.0021 18.3 0.0 0.0032 17.7 0.0 1.3 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Hce2 PF14856.6 ETS75051.1 - 2.8e-05 24.3 0.0 3.7e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Hce2 PF14856.6 ETS75052.1 - 9e-11 42.0 0.3 1.1e-10 41.7 0.3 1.1 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Malic_M PF03949.15 ETS75054.1 - 1.8e-88 296.1 0.4 2.6e-88 295.6 0.0 1.4 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain malic PF00390.19 ETS75054.1 - 1.5e-61 207.4 0.0 2.8e-61 206.5 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain RB_A PF01858.17 ETS75054.1 - 0.17 11.7 0.1 19 5.0 0.0 2.2 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain FliT PF05400.13 ETS75055.1 - 0.09 13.6 1.5 0.33 11.8 0.4 2.3 2 0 0 2 2 2 0 Flagellar protein FliT PglZ PF08665.12 ETS75059.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 PglZ domain DUF5427 PF10310.9 ETS75061.1 - 4.9e-180 599.4 0.0 5.6e-180 599.3 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Ribosomal_L14 PF00238.19 ETS75063.1 - 4.4e-32 110.7 0.0 4.8e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Hist_deacetyl PF00850.19 ETS75064.1 - 7.4e-83 278.5 0.1 1.8e-82 277.2 0.0 1.7 2 0 0 2 2 2 1 Histone deacetylase domain GST_N_3 PF13417.6 ETS75065.1 - 1.3e-09 38.3 0.0 4.9e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ETS75065.1 - 1.8e-09 37.7 0.0 3.8e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS75065.1 - 2.2e-05 24.4 0.0 3.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ETS75065.1 - 0.00016 21.8 0.1 0.00033 20.8 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ETS75065.1 - 0.0012 19.2 0.0 0.0024 18.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ETS75065.1 - 0.0026 17.9 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ETS75065.1 - 0.013 16.0 0.0 0.02 15.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Bac_luciferase PF00296.20 ETS75066.1 - 4e-64 217.0 5.5 5.2e-64 216.7 5.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase COesterase PF00135.28 ETS75067.1 - 8e-80 269.1 0.0 9.8e-71 239.2 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS75067.1 - 9.2e-14 51.8 0.1 1.7e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS75067.1 - 0.0002 22.0 2.6 0.00042 21.0 2.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ETS75067.1 - 0.046 13.2 0.1 0.091 12.2 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Fungal_trans PF04082.18 ETS75068.1 - 1.7e-13 50.2 0.1 2.7e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS75068.1 - 3.7e-09 36.5 7.9 8.1e-09 35.5 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ETS75069.1 - 1.5e-40 139.3 26.5 1.5e-40 139.3 26.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS75069.1 - 6.2e-09 35.2 10.2 6.2e-09 35.2 10.2 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter Borrelia_P13 PF05628.12 ETS75069.1 - 0.075 13.0 2.0 2.2 8.2 0.0 2.9 1 1 2 3 3 3 0 Borrelia membrane protein P13 DUF4191 PF13829.6 ETS75069.1 - 0.08 12.3 7.5 1.1 8.6 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) JAB PF01398.21 ETS75070.1 - 8.9e-33 112.8 0.0 1.7e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 ETS75070.1 - 4.6e-11 43.1 0.7 9.7e-11 42.1 0.7 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 ETS75070.1 - 3.5e-07 30.0 0.0 7.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain NPR1_interact PF15699.5 ETS75070.1 - 0.03 14.9 0.1 0.068 13.8 0.1 1.6 1 0 0 1 1 1 0 NPR1 interacting Ank_2 PF12796.7 ETS75072.1 - 3.7e-33 114.0 10.8 9e-08 32.6 0.1 6.1 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS75072.1 - 5.8e-22 75.4 9.8 0.00044 20.5 0.0 9.7 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 ETS75072.1 - 8.3e-22 77.0 8.5 0.0031 17.8 0.0 7.4 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS75072.1 - 3.1e-21 75.4 9.8 0.00016 22.2 0.4 6.5 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 ETS75072.1 - 4e-18 65.0 12.7 0.00038 20.8 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat Helo_like_N PF17111.5 ETS75072.1 - 0.0054 16.1 0.4 0.0054 16.1 0.4 1.9 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Polysacc_synt_4 PF04669.13 ETS75072.1 - 0.0079 15.8 0.3 0.021 14.4 0.3 1.6 1 0 0 1 1 1 1 Polysaccharide biosynthesis NACHT PF05729.12 ETS75072.1 - 0.018 15.0 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AnkUBD PF18418.1 ETS75072.1 - 0.078 13.1 0.9 3.5 7.8 0.1 3.5 2 1 1 3 3 3 0 Ankyrin ubiquitin-binding domain FR47 PF08445.10 ETS75073.1 - 6.7e-08 32.4 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 ETS75073.1 - 3.8e-07 30.1 0.0 5.5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS75073.1 - 1.5e-06 28.6 0.0 2.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS75073.1 - 1.9e-05 24.9 0.0 2.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ETS75073.1 - 0.00056 20.0 0.0 0.00089 19.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Bac_luciferase PF00296.20 ETS75073.1 - 0.051 13.0 0.1 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Luciferase-like monooxygenase DUF1330 PF07045.11 ETS75074.1 - 0.014 15.8 0.1 0.032 14.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) FAD-oxidase_C PF02913.19 ETS75075.1 - 7e-55 186.4 0.1 1.1e-54 185.7 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ETS75075.1 - 2.3e-36 124.6 0.0 4.8e-36 123.6 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain SRP54 PF00448.22 ETS75075.1 - 0.089 12.4 0.1 0.37 10.4 0.2 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Clr5 PF14420.6 ETS75076.1 - 4.3e-21 74.9 6.6 6e-21 74.4 0.8 3.3 4 0 0 4 4 4 1 Clr5 domain Fungal_trans PF04082.18 ETS75077.1 - 2.3e-23 82.6 0.1 4.9e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS75077.1 - 0.0056 16.8 9.4 0.011 15.8 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tox-MPTase5 PF15641.6 ETS75077.1 - 0.0095 16.0 0.0 0.073 13.1 0.0 2.2 2 0 0 2 2 2 1 Metallopeptidase toxin 5 Claudin_3 PF06653.11 ETS75077.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Glyco_tranf_2_3 PF13641.6 ETS75078.1 - 5.9e-25 88.5 0.0 8.3e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ETS75078.1 - 1.3e-07 31.6 0.0 2.9e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ETS75078.1 - 3.3e-07 30.0 0.0 7.3e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Gp45_2 PF17470.2 ETS75078.1 - 0.035 14.1 0.1 0.094 12.7 0.1 1.7 1 0 0 1 1 1 0 Phage gene product 45.2 Glyco_hydro_76 PF03663.14 ETS75080.1 - 9.6e-138 459.7 4.7 1.2e-137 459.3 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Aldo_ket_red PF00248.21 ETS75081.1 - 5.2e-78 262.2 0.0 5.9e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_115 PF15979.5 ETS75082.1 - 1.1e-139 465.6 0.1 1.5e-139 465.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 ETS75082.1 - 6.7e-49 166.0 0.0 1.2e-48 165.2 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Ank_2 PF12796.7 ETS75084.1 - 6.8e-51 170.8 15.0 6e-15 55.6 0.2 6.6 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS75084.1 - 8.2e-35 114.9 12.4 0.00056 20.2 0.1 12.7 13 0 0 13 13 13 7 Ankyrin repeat Ank_4 PF13637.6 ETS75084.1 - 1.7e-34 117.7 9.3 8.7e-08 32.6 0.0 9.5 4 3 6 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS75084.1 - 1.6e-32 111.1 13.5 3.1e-07 30.5 0.1 9.4 6 3 3 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 ETS75084.1 - 1.2e-28 98.2 15.4 0.00024 21.4 0.1 10.7 9 2 1 10 10 10 8 Ankyrin repeat NACHT PF05729.12 ETS75084.1 - 6.3e-11 42.5 0.4 1.4e-10 41.4 0.4 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS75084.1 - 0.0047 17.3 0.1 0.027 14.8 0.1 2.4 1 0 0 1 1 1 1 AAA ATPase domain DUF3447 PF11929.8 ETS75084.1 - 0.071 13.1 0.3 7.1 6.7 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) RNA_helicase PF00910.22 ETS75084.1 - 0.075 13.4 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 ETS75084.1 - 0.11 12.8 0.0 0.36 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Myotub-related PF06602.14 ETS75085.1 - 0.14 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Abhydrolase_6 PF12697.7 ETS75086.1 - 0.00026 21.7 0.1 0.013 16.1 0.1 2.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3447 PF11929.8 ETS75086.1 - 0.14 12.1 0.0 0.49 10.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) Arf PF00025.21 ETS75086.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Big_7 PF17957.1 ETS75086.1 - 1.3 9.8 4.0 0.85 10.4 0.2 2.5 3 0 0 3 3 3 0 Bacterial Ig domain DUF3938 PF13074.6 ETS75087.1 - 0.079 13.2 1.1 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) DUF805 PF05656.14 ETS75087.1 - 8.5 6.8 18.6 0.13 12.7 9.3 2.6 2 2 1 3 3 3 0 Protein of unknown function (DUF805) RRM_1 PF00076.22 ETS75088.1 - 0.19 11.6 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EVC2_like PF12297.8 ETS75089.1 - 0.17 10.5 0.0 0.17 10.5 0.0 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein HEAT_2 PF13646.6 ETS75090.1 - 2.2e-17 63.2 11.0 2.5e-08 34.2 1.2 5.6 2 2 1 4 4 4 4 HEAT repeats NACHT PF05729.12 ETS75090.1 - 2e-15 57.1 0.4 1e-14 54.8 0.0 2.3 2 0 0 2 2 2 1 NACHT domain NLRC4_HD2 PF17776.1 ETS75090.1 - 7.9e-07 29.7 0.1 3.1e-06 27.7 0.1 2.2 1 0 0 1 1 1 1 NLRC4 helical domain HD2 Adaptin_N PF01602.20 ETS75090.1 - 4e-05 22.4 1.6 0.00019 20.2 0.6 2.1 2 0 0 2 2 2 1 Adaptin N terminal region HEAT PF02985.22 ETS75090.1 - 4.3e-05 23.4 1.0 0.33 11.3 0.0 5.0 6 0 0 6 6 5 1 HEAT repeat NB-ARC PF00931.22 ETS75090.1 - 0.0001 21.6 0.5 0.00037 19.8 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 ETS75090.1 - 0.00044 20.5 0.0 0.0018 18.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS75090.1 - 0.00074 19.9 0.0 0.0046 17.4 0.0 2.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ETS75090.1 - 0.0017 18.9 0.0 0.011 16.3 0.0 2.5 2 0 0 2 2 1 1 AAA domain DNA_alkylation PF08713.11 ETS75090.1 - 0.01 15.6 4.9 0.36 10.5 0.8 2.7 1 1 1 2 2 2 2 DNA alkylation repair enzyme PGAP1 PF07819.13 ETS75090.1 - 0.018 14.8 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein NTPase_1 PF03266.15 ETS75090.1 - 0.036 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 NTPase RTP1_C1 PF10363.9 ETS75090.1 - 0.053 13.7 0.9 4.1 7.6 0.1 3.2 1 1 2 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 ETS75090.1 - 0.054 14.0 1.2 1.5e+02 3.0 0.1 4.8 4 2 2 6 6 5 0 HEAT-like repeat RsgA_GTPase PF03193.16 ETS75090.1 - 0.058 13.3 0.1 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase RNA_helicase PF00910.22 ETS75090.1 - 0.07 13.5 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Vitellogenin_N PF01347.22 ETS75090.1 - 0.085 11.2 0.8 0.28 9.5 0.2 1.8 1 1 1 2 2 2 0 Lipoprotein amino terminal region ABC_tran PF00005.27 ETS75090.1 - 0.091 13.3 0.1 0.6 10.6 0.0 2.3 2 0 0 2 2 2 0 ABC transporter SIL1 PF16782.5 ETS75090.1 - 0.11 11.7 3.3 0.26 10.5 3.3 1.6 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 Vac14_Fab1_bd PF12755.7 ETS75090.1 - 0.12 13.0 0.2 37 5.0 0.0 4.4 3 2 2 5 5 5 0 Vacuolar 14 Fab1-binding region MMR_HSR1 PF01926.23 ETS75090.1 - 0.15 12.1 0.0 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase TniB PF05621.11 ETS75090.1 - 0.18 11.2 1.2 18 4.7 0.1 2.9 3 0 0 3 3 3 0 Bacterial TniB protein MeaB PF03308.16 ETS75090.1 - 0.2 10.6 0.0 0.37 9.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB F-box PF00646.33 ETS75091.1 - 0.16 11.9 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 F-box domain Kinesin PF00225.23 ETS75092.1 - 9.9e-117 389.6 0.0 1.4e-116 389.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ETS75092.1 - 2.4e-27 95.7 0.0 4.8e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Herpes_UL14 PF03580.14 ETS75092.1 - 0.014 15.7 2.8 0.014 15.7 2.8 1.9 2 0 0 2 2 2 0 Herpesvirus UL14-like protein AAA_33 PF13671.6 ETS75092.1 - 0.074 13.2 0.0 0.44 10.7 0.0 2.4 1 1 0 1 1 1 0 AAA domain TAP42 PF04177.12 ETS75092.1 - 0.098 11.8 4.1 0.21 10.7 4.1 1.6 1 0 0 1 1 1 0 TAP42-like family MAGI_u1 PF16663.5 ETS75092.1 - 0.32 11.1 2.3 0.44 10.7 0.1 2.5 2 0 0 2 2 2 0 Unstructured region on MAGI Atg14 PF10186.9 ETS75094.1 - 2.5e-15 56.4 4.1 4e-10 39.3 0.0 3.0 2 1 1 3 3 3 2 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 ETS75094.1 - 5.4e-10 38.7 0.0 5.9e-06 25.4 0.0 2.9 3 0 0 3 3 3 2 Vacuolar protein sorting 38 Snapin_Pallidin PF14712.6 ETS75094.1 - 2 8.9 8.0 0.15 12.5 0.5 2.7 3 0 0 3 3 3 0 Snapin/Pallidin DUF3138 PF11336.8 ETS75094.1 - 4.4 5.8 5.8 11 4.4 1.7 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3138) WD40 PF00400.32 ETS75095.1 - 3.1e-07 31.0 5.1 0.17 12.8 0.3 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Zn_Tnp_IS1595 PF12760.7 ETS75095.1 - 0.0012 18.8 1.1 0.0012 18.8 1.1 2.5 2 0 0 2 2 2 1 Transposase zinc-ribbon domain Ribosomal_L37ae PF01780.19 ETS75095.1 - 0.0026 17.8 1.5 0.006 16.6 1.5 1.6 1 0 0 1 1 1 1 Ribosomal L37ae protein family ANAPC4_WD40 PF12894.7 ETS75095.1 - 0.0054 17.0 0.1 0.44 10.9 0.1 3.6 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Elf1 PF05129.13 ETS75095.1 - 0.1 12.7 2.5 0.29 11.2 1.6 2.3 3 1 0 3 3 3 0 Transcription elongation factor Elf1 like TF_Zn_Ribbon PF08271.12 ETS75095.1 - 0.23 11.0 1.2 0.68 9.5 1.2 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding zf-TFIIB PF13453.6 ETS75095.1 - 0.88 9.0 5.2 0.58 9.5 1.5 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger DUF4379 PF14311.6 ETS75095.1 - 8.4 6.8 9.8 6.9 7.1 0.6 3.0 2 1 0 2 2 2 0 Probable Zinc-ribbon domain DHDPS PF00701.22 ETS75096.1 - 6.8e-41 139.9 0.0 7.8e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family zf-C2H2 PF00096.26 ETS75098.1 - 8.4e-11 41.7 7.1 0.00014 22.1 0.2 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS75098.1 - 1.1e-08 35.1 3.6 0.008 16.9 0.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ETS75098.1 - 1.9e-06 28.0 1.6 0.019 15.2 0.1 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ETS75098.1 - 0.00034 20.9 2.5 0.42 10.9 0.4 2.5 2 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 ETS75098.1 - 0.00081 19.3 1.6 1.4 9.0 0.1 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger AMP-binding_C PF13193.6 ETS75098.1 - 0.036 15.1 0.0 20 6.3 0.0 2.5 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain zf-met PF12874.7 ETS75098.1 - 0.042 14.3 2.5 2.6 8.6 0.1 3.3 3 1 0 3 3 3 0 Zinc-finger of C2H2 type zf-BED PF02892.15 ETS75098.1 - 0.064 13.3 2.5 5.1 7.2 0.0 3.2 3 0 0 3 3 3 0 BED zinc finger zf-H2C2_5 PF13909.6 ETS75098.1 - 0.067 13.0 5.8 2.8 7.8 0.6 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-HYPF PF07503.12 ETS75098.1 - 0.55 10.0 6.0 0.32 10.8 1.1 2.7 3 0 0 3 3 3 0 HypF finger zf-H2C2_2 PF13465.6 ETS75098.1 - 4.9 7.7 10.7 4.4 7.9 0.6 4.0 5 1 0 5 5 5 0 Zinc-finger double domain OTT_1508_deam PF14441.6 ETS75099.1 - 1.1e-21 76.6 0.9 2.6e-21 75.4 0.9 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase PNP_UDP_1 PF01048.20 ETS75100.1 - 1.2e-09 37.8 0.7 8.4e-09 35.0 0.7 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.7 ETS75100.1 - 7.8e-05 23.2 0.5 0.0002 21.9 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS75100.1 - 0.13 12.8 0.1 1.7 9.5 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat HET PF06985.11 ETS75102.1 - 1.4e-12 48.1 4.0 5.2e-10 39.9 0.5 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) BSP_II PF05432.11 ETS75104.1 - 3.5e-05 23.7 5.6 3.9e-05 23.5 5.6 1.0 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DNA_pol_phi PF04931.13 ETS75104.1 - 0.00029 19.1 12.0 0.00033 18.9 12.0 1.0 1 0 0 1 1 1 1 DNA polymerase phi Nop14 PF04147.12 ETS75104.1 - 0.00078 17.8 6.9 0.0008 17.8 6.9 1.1 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.12 ETS75104.1 - 0.0022 16.5 5.5 0.0023 16.4 5.5 1.1 1 0 0 1 1 1 1 Mpp10 protein SDA1 PF05285.12 ETS75104.1 - 0.0043 16.5 9.4 0.0048 16.4 9.4 1.1 1 0 0 1 1 1 1 SDA1 RXT2_N PF08595.11 ETS75104.1 - 0.018 15.1 6.3 0.026 14.5 6.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Beta-APP PF03494.13 ETS75104.1 - 0.022 14.6 0.5 0.041 13.7 0.5 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Myc_N PF01056.18 ETS75104.1 - 0.039 13.8 3.3 0.052 13.4 3.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Pox_Ag35 PF03286.14 ETS75104.1 - 0.047 13.5 3.7 0.068 13.0 3.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sporozoite_P67 PF05642.11 ETS75104.1 - 0.063 11.4 5.2 0.077 11.1 5.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Roughex PF06020.11 ETS75104.1 - 0.088 11.9 3.9 0.092 11.8 3.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF913 PF06025.12 ETS75104.1 - 0.16 10.9 0.3 0.17 10.8 0.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4820 PF16091.5 ETS75104.1 - 0.18 11.1 1.0 0.24 10.8 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) eIF-3c_N PF05470.12 ETS75104.1 - 0.27 9.5 4.3 0.31 9.3 4.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PPP4R2 PF09184.11 ETS75104.1 - 2.1 7.8 17.3 2.9 7.4 17.3 1.1 1 0 0 1 1 1 0 PPP4R2 TLP-20 PF06088.11 ETS75104.1 - 3.5 7.5 7.1 5.2 6.9 7.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) NOA36 PF06524.12 ETS75104.1 - 4.4 6.6 23.8 6.1 6.1 23.8 1.2 1 0 0 1 1 1 0 NOA36 protein Tom22 PF04281.13 ETS75104.1 - 4.5 7.0 9.2 7.6 6.3 9.2 1.4 1 1 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 SGT1 PF07093.11 ETS75104.1 - 4.7 5.5 8.7 6.9 5.0 8.7 1.3 1 0 0 1 1 1 0 SGT1 protein Sigma70_ner PF04546.13 ETS75104.1 - 5.3 6.9 13.8 7 6.5 13.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region TFB6 PF17110.5 ETS75104.1 - 5.8 6.6 8.2 8.2 6.1 8.2 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Glyco_hydro_79C PF16862.5 ETS75105.1 - 7.5e-19 68.5 1.2 2e-18 67.1 1.2 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain CG-1 PF03859.16 ETS75105.1 - 0.082 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 CG-1 domain Helicase_C PF00271.31 ETS75106.1 - 4.9e-25 88.0 0.0 1.3e-24 86.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ETS75106.1 - 1.4e-23 83.6 0.1 8.6e-23 81.0 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ETS75106.1 - 0.00025 21.1 0.1 0.00077 19.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 ETS75106.1 - 0.049 12.4 0.2 0.1 11.4 0.0 1.6 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer ABC_tran PF00005.27 ETS75107.1 - 1.4e-48 164.9 0.2 4.6e-27 95.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS75107.1 - 2.7e-29 102.7 28.2 2e-24 86.7 16.6 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ETS75107.1 - 3.1e-11 43.1 0.4 0.0014 18.1 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ETS75107.1 - 1.9e-08 34.7 0.9 0.0016 18.7 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 ETS75107.1 - 1.6e-07 31.5 1.2 0.068 13.0 0.0 4.3 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MobB PF03205.14 ETS75107.1 - 0.00012 21.9 1.4 0.038 13.9 0.0 3.3 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 ETS75107.1 - 0.00014 21.8 0.9 0.17 11.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 ETS75107.1 - 0.00015 21.4 1.8 0.16 11.5 0.4 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 ETS75107.1 - 0.00016 22.1 0.1 0.2 12.1 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 ETS75107.1 - 0.00026 20.1 0.3 0.013 14.6 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA PF00004.29 ETS75107.1 - 0.0009 19.7 0.0 0.53 10.7 0.0 3.2 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ETS75107.1 - 0.0012 18.4 0.3 0.075 12.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region SbcCD_C PF13558.6 ETS75107.1 - 0.0012 19.0 0.4 1 9.7 0.1 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 ETS75107.1 - 0.0016 18.1 0.8 0.073 12.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Roc PF08477.13 ETS75107.1 - 0.0018 18.5 0.3 1.3 9.3 0.0 3.9 4 0 0 4 4 3 1 Ras of Complex, Roc, domain of DAPkinase TrwB_AAD_bind PF10412.9 ETS75107.1 - 0.0019 17.2 2.2 0.0052 15.7 0.1 2.1 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 ETS75107.1 - 0.0023 17.7 1.1 1.1 9.0 0.2 3.2 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 ETS75107.1 - 0.007 16.3 0.1 3.9 7.4 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Pox_A32 PF04665.12 ETS75107.1 - 0.012 15.1 1.4 0.58 9.6 0.0 2.7 3 0 0 3 3 2 0 Poxvirus A32 protein AAA_23 PF13476.6 ETS75107.1 - 0.015 15.8 0.1 0.83 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ETS75107.1 - 0.016 15.4 0.3 9.1 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ETS75107.1 - 0.016 15.3 0.1 0.96 9.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 ETS75107.1 - 0.021 14.9 0.5 2.8 8.0 0.0 2.7 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 ETS75107.1 - 0.023 14.1 1.5 0.037 13.4 0.1 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 ETS75107.1 - 0.023 13.9 3.6 3.9 6.6 0.0 3.7 2 1 1 3 3 3 0 NB-ARC domain NTPase_1 PF03266.15 ETS75107.1 - 0.029 14.3 1.9 0.16 11.9 0.0 2.9 4 0 0 4 4 3 0 NTPase TsaE PF02367.17 ETS75107.1 - 0.032 14.2 0.0 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CbiA PF01656.23 ETS75107.1 - 0.035 14.2 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF815 PF05673.13 ETS75107.1 - 0.039 13.1 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF87 PF01935.17 ETS75107.1 - 0.039 14.0 1.6 0.088 12.9 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain Mg_chelatase PF01078.21 ETS75107.1 - 0.066 12.6 0.1 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 ETS75107.1 - 0.08 12.7 2.0 0.64 9.7 0.0 3.0 4 0 0 4 4 2 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 ETS75107.1 - 0.1 12.3 0.9 17 5.1 0.0 3.3 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase PRK PF00485.18 ETS75107.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.6 ETS75107.1 - 0.15 12.4 1.5 7.3 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 ETS75107.1 - 0.32 10.8 1.0 4.2 7.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain SLATT_1 PF18181.1 ETS75107.1 - 8.6 6.3 6.8 1.7 8.6 1.1 2.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Fungal_trans_2 PF11951.8 ETS75108.1 - 1.8e-17 63.2 1.7 4.4e-17 62.0 1.7 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain AC_N PF16214.5 ETS75108.1 - 0.32 10.1 1.5 0.5 9.4 1.5 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Conotoxin PF02950.17 ETS75108.1 - 3.9 8.6 5.1 3.6 8.7 0.1 2.9 3 0 0 3 3 3 0 Conotoxin GMC_oxred_N PF00732.19 ETS75109.1 - 6.1e-52 176.8 0.0 7.7e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS75109.1 - 1.2e-34 119.9 0.0 2.4e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS75109.1 - 4.6e-06 26.0 0.2 0.069 12.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 ETS75109.1 - 0.0012 18.2 0.1 0.0025 17.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 ETS75109.1 - 0.0017 17.5 0.0 0.005 15.9 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ETS75109.1 - 0.015 14.6 0.0 0.035 13.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS75109.1 - 0.028 14.6 0.2 0.095 12.9 0.3 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS75109.1 - 0.21 11.1 0.3 0.44 10.1 0.3 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ank_4 PF13637.6 ETS75110.1 - 3.9e-05 24.1 0.0 0.87 10.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS75110.1 - 7.9e-05 23.2 0.0 0.11 13.1 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS75110.1 - 0.00021 21.4 0.1 0.46 11.2 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 ETS75110.1 - 0.00036 20.8 0.2 0.036 14.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 ETS75110.1 - 0.11 13.0 0.2 0.7 10.4 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Dodecin PF07311.12 ETS75110.1 - 0.19 12.0 0.2 0.46 10.8 0.2 1.6 1 0 0 1 1 1 0 Dodecin NACHT PF05729.12 ETS75111.1 - 1.5e-05 25.0 0.0 0.00011 22.1 0.0 2.3 2 0 0 2 2 2 1 NACHT domain SesA PF17107.5 ETS75111.1 - 0.0016 18.7 0.2 0.0064 16.7 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_16 PF13191.6 ETS75111.1 - 0.0066 16.8 0.3 0.036 14.4 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ETS75111.1 - 0.043 14.1 0.2 2.6 8.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 ETS75111.1 - 0.075 13.5 0.0 0.28 11.7 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 ETS75111.1 - 0.093 13.2 1.3 1.3 9.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ETS75111.1 - 0.18 11.6 0.1 0.73 9.6 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ADH_N PF08240.12 ETS75112.1 - 6.5e-31 106.4 0.6 2.6e-30 104.5 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS75112.1 - 2.9e-23 82.3 0.1 5e-23 81.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS75112.1 - 4.5e-10 39.4 0.6 6.9e-10 38.8 0.6 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ETS75112.1 - 7.4e-07 30.3 0.0 2.3e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ETS75112.1 - 5.2e-05 22.6 1.1 8.9e-05 21.9 1.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 ETS75112.1 - 0.00085 18.6 0.1 0.0019 17.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS75112.1 - 0.0045 17.5 0.0 0.075 13.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS75112.1 - 0.008 14.9 0.2 0.011 14.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 ETS75112.1 - 0.041 13.5 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 ETS75112.1 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 ETS75112.1 - 0.092 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.21 ETS75112.1 - 0.14 12.2 0.7 0.49 10.4 0.5 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Mannosidase_ig PF17786.1 ETS75113.1 - 8.8e-14 51.9 0.0 2.4e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 ETS75113.1 - 1.5e-11 45.0 1.2 5.1e-11 43.2 0.3 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 ETS75113.1 - 3.6e-05 23.4 0.0 0.00011 21.9 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 ETS75113.1 - 5.4e-05 23.2 0.0 0.00018 21.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 ETS75113.1 - 0.007 15.5 0.4 0.023 13.8 0.4 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF2236 PF09995.9 ETS75114.1 - 8.2e-46 157.0 2.6 1.2e-45 156.5 2.6 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) dsrm PF00035.26 ETS75115.1 - 5.4e-05 23.8 0.0 9.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif adh_short PF00106.25 ETS75116.1 - 9.5e-34 116.6 0.8 1.2e-33 116.3 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS75116.1 - 2.4e-30 105.8 0.7 2.8e-30 105.6 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS75116.1 - 1.3e-09 38.3 0.4 3.6e-09 36.8 0.4 1.8 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 ETS75116.1 - 0.0039 16.2 0.1 0.067 12.2 0.1 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ras PF00071.22 ETS75117.1 - 6.2e-42 143.0 0.0 8.1e-42 142.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS75117.1 - 1.3e-29 102.8 0.0 1.8e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS75117.1 - 1.6e-10 40.7 0.0 1.3e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ETS75117.1 - 0.00035 20.6 0.0 0.00054 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 ETS75117.1 - 0.017 14.8 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 ETS75117.1 - 0.022 14.7 0.0 0.091 12.7 0.0 2.0 1 1 1 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 ETS75117.1 - 0.022 14.1 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 ETS75117.1 - 0.023 14.9 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ETS75117.1 - 0.033 14.4 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ETS75117.1 - 0.055 13.8 0.0 0.091 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ETS75117.1 - 0.091 13.1 0.1 0.2 12.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 ETS75117.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.10 ETS75117.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 ETS75117.1 - 0.22 11.0 0.0 0.36 10.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region 2-Hacid_dh_C PF02826.19 ETS75119.1 - 3e-44 150.5 0.0 4.1e-43 146.8 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS75119.1 - 1.9e-05 24.3 0.0 2.4e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AOC_like PF18678.1 ETS75119.1 - 0.068 12.8 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain NAD_binding_2 PF03446.15 ETS75119.1 - 0.086 13.0 0.2 0.32 11.2 0.1 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase MFS_1 PF07690.16 ETS75122.1 - 7.6e-49 166.5 48.0 7.6e-49 166.5 48.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS75122.1 - 5.6e-26 91.1 15.4 7.8e-26 90.6 15.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS75122.1 - 6.6e-12 45.0 11.7 6.6e-12 45.0 11.7 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter DUF3493 PF11998.8 ETS75123.1 - 0.015 15.4 0.4 0.05 13.8 0.4 1.9 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 Wzy_C PF04932.15 ETS75123.1 - 1.4 8.6 8.6 5.5 6.6 0.1 2.5 2 0 0 2 2 2 0 O-Antigen ligase Esterase_phd PF10503.9 ETS75124.1 - 1.8e-21 76.7 1.2 2.5e-21 76.2 1.2 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ETS75124.1 - 2.1e-09 37.2 1.5 3.1e-09 36.6 1.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ETS75124.1 - 0.004 17.0 0.1 0.0069 16.2 0.1 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 ETS75124.1 - 0.0058 16.5 0.3 0.0086 15.9 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS75124.1 - 0.0086 15.0 2.0 0.016 14.1 0.4 1.8 2 0 0 2 2 2 1 Carboxylesterase family Esterase PF00756.20 ETS75124.1 - 0.2 11.3 3.1 0.19 11.3 1.9 1.4 1 1 0 1 1 1 0 Putative esterase Sulfotransfer_4 PF17784.1 ETS75125.1 - 6.9e-51 173.1 0.0 8.1e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ETS75125.1 - 0.00036 21.0 0.0 0.00067 20.1 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Peptidase_S8 PF00082.22 ETS75127.1 - 3e-28 98.9 16.0 3e-28 98.9 16.0 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ETS75127.1 - 3.1e-18 66.2 0.1 6.2e-18 65.2 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Zip PF02535.22 ETS75128.1 - 4.5e-55 187.2 0.3 7.4e-55 186.5 0.3 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Pkinase PF00069.25 ETS75130.1 - 1.2e-69 234.6 0.0 2.6e-69 233.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS75130.1 - 1.1e-32 113.4 0.0 3.3e-31 108.5 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS75130.1 - 0.00041 19.8 0.0 0.45 9.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 ETS75130.1 - 0.029 14.3 2.9 0.057 13.3 0.1 2.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ETS75130.1 - 0.031 13.1 0.2 0.079 11.7 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 ETS75130.1 - 0.053 13.1 0.4 0.15 11.7 0.4 1.8 1 1 0 1 1 1 0 RIO1 family Glyco_hydro_12 PF01670.16 ETS75132.1 - 9.3e-52 176.1 12.8 1.1e-51 175.8 12.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 MF_alpha_N PF05436.11 ETS75132.1 - 0.11 12.4 0.2 0.24 11.3 0.2 1.6 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus SMP PF04927.12 ETS75133.1 - 1.3e-11 44.8 5.2 1.1e-07 32.2 0.7 2.1 2 0 0 2 2 2 2 Seed maturation protein zf-C2H2_4 PF13894.6 ETS75134.1 - 5.1e-13 48.7 16.5 0.013 16.3 0.4 4.9 5 0 0 5 5 4 4 C2H2-type zinc finger zf-met PF12874.7 ETS75134.1 - 2e-12 47.1 17.3 1.2e-05 25.6 1.4 4.0 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ETS75134.1 - 2.3e-12 46.9 15.7 6.8e-05 23.0 2.1 4.1 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 ETS75134.1 - 1.1e-10 41.4 22.7 0.0012 19.2 2.4 5.2 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 ETS75134.1 - 3.6e-07 30.4 14.7 0.019 15.3 0.8 4.1 2 2 2 4 4 4 3 C2H2 type zinc-finger (2 copies) zf_ZIC PF18366.1 ETS75134.1 - 0.00013 21.9 7.1 0.48 10.6 0.0 3.6 3 1 1 4 4 4 2 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 ETS75134.1 - 0.0009 19.4 3.2 0.0058 16.8 3.2 2.3 1 1 0 1 1 1 1 Aberrant zinc-finger zf-H2C2_2 PF13465.6 ETS75134.1 - 0.0031 17.9 17.6 0.31 11.5 0.4 4.9 5 0 0 5 5 4 2 Zinc-finger double domain Rad50_zn_hook PF04423.14 ETS75134.1 - 0.0069 16.2 0.5 2.2 8.2 0.0 3.0 2 1 1 3 3 3 1 Rad50 zinc hook motif zf-C2H2_9 PF16293.5 ETS75134.1 - 0.031 14.1 9.6 0.94 9.4 0.7 3.7 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-DNA_Pol PF08996.10 ETS75134.1 - 0.037 13.8 6.8 0.098 12.4 0.7 2.1 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger DUF1360 PF07098.11 ETS75134.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) zf-Di19 PF05605.12 ETS75134.1 - 0.18 12.2 0.2 0.18 12.2 0.2 3.6 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 ETS75134.1 - 0.31 11.0 12.2 0.6 10.1 0.2 4.5 4 0 0 4 4 4 0 zinc-finger of a C2HC-type IBR PF01485.21 ETS75134.1 - 0.49 10.7 14.8 2.2 8.6 0.5 3.2 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-C2H2_6 PF13912.6 ETS75134.1 - 0.61 10.2 18.0 1.5 9.0 0.8 4.8 4 1 1 5 5 5 0 C2H2-type zinc finger zf-DBF PF07535.12 ETS75134.1 - 1.2 9.4 10.1 1.4 9.0 1.1 3.3 3 0 0 3 3 3 0 DBF zinc finger AKAP95 PF04988.12 ETS75134.1 - 2.3 8.5 8.1 2.6 8.2 0.7 3.0 2 2 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_11 PF16622.5 ETS75134.1 - 2.5 8.0 11.5 1.3 8.8 0.5 3.8 4 0 0 4 4 3 0 zinc-finger C2H2-type zinc_ribbon_9 PF14369.6 ETS75134.1 - 7.8 6.8 17.5 0.53 10.6 5.9 3.7 2 2 0 2 2 2 0 zinc-ribbon zf-BED PF02892.15 ETS75134.1 - 9.4 6.4 20.3 4.5 7.4 1.0 4.1 4 0 0 4 4 4 0 BED zinc finger Pkinase PF00069.25 ETS75135.1 - 4.6e-62 209.8 0.0 1.1e-61 208.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS75135.1 - 4.9e-35 121.1 0.0 3.6e-29 101.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ETS75135.1 - 1.9e-07 30.7 0.0 0.00037 19.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 ETS75135.1 - 0.0018 18.2 0.2 0.005 16.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ETS75135.1 - 0.019 13.9 0.1 0.03 13.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 ETS75135.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ETS75135.1 - 0.089 11.6 0.0 0.089 11.6 0.0 2.3 3 0 0 3 3 3 0 Fungal protein kinase RIO1 PF01163.22 ETS75135.1 - 0.26 10.9 0.0 0.51 9.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family GWT1 PF06423.12 ETS75136.1 - 1.9e-43 148.1 1.4 1.9e-43 148.1 1.4 2.0 2 1 0 2 2 2 1 GWT1 DUF4818 PF16089.5 ETS75136.1 - 0.0032 17.9 0.0 0.0032 17.9 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4818) BatA PF07584.11 ETS75136.1 - 0.41 11.0 5.1 0.36 11.2 0.6 3.3 3 1 1 4 4 4 0 Aerotolerance regulator N-terminal AltA1 PF16541.5 ETS75138.1 - 1.3e-29 103.2 2.4 1.3e-29 103.2 2.4 1.3 2 0 0 2 2 2 1 Alternaria alternata allergen 1 Rax2 PF12768.7 ETS75139.1 - 7.9e-06 25.5 0.1 1.6e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Podoplanin PF05808.11 ETS75139.1 - 0.00057 20.0 2.4 0.001 19.2 2.4 1.4 1 0 0 1 1 1 1 Podoplanin Mid2 PF04478.12 ETS75139.1 - 0.0023 17.8 0.5 0.0036 17.2 0.3 1.6 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 ETS75139.1 - 0.0071 15.7 0.7 0.025 14.0 0.7 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Shisa PF13908.6 ETS75139.1 - 0.05 13.9 4.0 0.056 13.7 2.8 1.7 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator AJAP1_PANP_C PF15298.6 ETS75139.1 - 0.054 13.7 5.2 0.086 13.0 5.2 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus TMEM132D_C PF15706.5 ETS75139.1 - 0.13 12.0 0.2 0.28 11.0 0.0 1.6 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4381 PF14316.6 ETS75139.1 - 0.14 12.4 0.3 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Alpha_GJ PF03229.13 ETS75139.1 - 0.58 10.7 9.1 1.1 9.8 9.1 1.5 1 0 0 1 1 1 0 Alphavirus glycoprotein J GT87 PF09594.10 ETS75139.1 - 0.81 9.3 4.2 1.2 8.8 0.2 2.3 2 1 0 2 2 2 0 Glycosyltransferase family 87 TFIIA PF03153.13 ETS75139.1 - 3.1 7.7 10.3 4 7.3 10.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyoxalase PF00903.25 ETS75140.1 - 1.5e-12 47.9 0.0 2.7e-12 47.0 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ETS75140.1 - 1.7e-07 31.5 0.0 3e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 ETS75140.1 - 4.4e-06 26.9 0.1 0.00012 22.2 0.1 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 ETS75140.1 - 2.4e-05 24.2 0.0 7.1e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 ETS75140.1 - 0.0024 18.7 0.0 0.0069 17.2 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Glyco_transf_28 PF03033.20 ETS75141.1 - 2.5e-16 60.0 0.0 1.5e-15 57.5 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 ETS75141.1 - 2e-06 26.9 0.1 3.4e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ETS75141.1 - 0.0063 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain FOLN PF09289.10 ETS75142.1 - 0.026 14.7 0.6 1.2 9.4 0.2 2.4 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain Sugar_tr PF00083.24 ETS75143.1 - 4.4e-95 319.2 18.5 5.2e-95 319.0 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS75143.1 - 2.6e-22 79.2 17.1 2.6e-22 79.2 17.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS75143.1 - 0.003 16.0 5.3 0.025 13.0 1.0 2.4 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ETS75144.1 - 2.6e-40 138.4 28.4 2.6e-40 138.4 28.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS75144.1 - 8.2e-11 41.4 19.1 1.2e-10 40.9 19.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter adh_short_C2 PF13561.6 ETS75145.1 - 1.4e-60 204.7 0.1 1.8e-60 204.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS75145.1 - 3.4e-49 167.0 0.3 4.4e-49 166.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS75145.1 - 1.6e-10 41.2 0.0 2.9e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS75145.1 - 2.7e-06 27.0 0.0 4.5e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ETS75145.1 - 0.0022 18.2 0.1 0.0035 17.6 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_3 PF03447.16 ETS75145.1 - 0.0071 17.0 0.3 0.12 13.0 0.3 2.1 1 1 1 2 2 2 1 Homoserine dehydrogenase, NAD binding domain TrkA_N PF02254.18 ETS75145.1 - 0.016 15.5 0.1 0.028 14.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 ETS75145.1 - 0.017 15.0 0.2 0.024 14.5 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Aldedh PF00171.22 ETS75147.1 - 1.2e-150 502.1 0.1 1.5e-150 501.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short_C2 PF13561.6 ETS75148.1 - 1.2e-47 162.4 0.1 1.5e-47 162.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS75148.1 - 4.4e-42 143.7 0.6 5.6e-42 143.4 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS75148.1 - 1.7e-10 41.1 0.5 2.4e-10 40.6 0.5 1.1 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 ETS75148.1 - 0.036 14.0 0.5 0.38 10.7 0.5 2.2 1 1 0 1 1 1 0 Zinc-binding dehydrogenase zf-C2H2_4 PF13894.6 ETS75149.1 - 7.5e-08 32.6 2.1 0.0039 17.9 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ETS75149.1 - 1.6e-06 28.3 3.1 0.0068 16.8 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ETS75149.1 - 0.098 12.7 1.3 1.4 9.0 0.3 2.3 1 1 1 2 2 2 0 C2H2-type zinc finger Myofilin PF15929.5 ETS75149.1 - 0.1 13.0 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 Myofilin Ima1_N PF09779.9 ETS75149.1 - 0.33 11.8 2.3 0.39 11.6 0.1 2.1 2 1 0 2 2 2 0 Ima1 N-terminal domain Ribosomal_60s PF00428.19 ETS75149.1 - 0.4 11.3 8.3 0.075 13.6 2.7 2.3 2 1 1 3 3 3 0 60s Acidic ribosomal protein Meth_synt_2 PF01717.18 ETS75150.1 - 5.8e-08 32.4 0.0 1e-06 28.3 0.0 2.4 2 1 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain AhpC-TSA PF00578.21 ETS75152.1 - 5.3e-29 100.7 0.0 7.2e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ETS75152.1 - 1.9e-12 47.1 0.0 2.6e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ETS75152.1 - 2.3e-11 43.4 0.1 4.9e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kelch_3 PF13415.6 ETS75153.1 - 6.4e-16 58.2 7.1 8.6e-10 38.7 0.0 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 ETS75153.1 - 1.1e-14 54.0 0.6 1.3e-06 28.3 0.1 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 ETS75153.1 - 9.3e-14 51.2 0.0 0.00019 21.4 0.0 4.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 ETS75153.1 - 4e-12 46.0 3.2 0.001 19.3 0.0 5.0 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.25 ETS75153.1 - 6.2e-12 44.9 0.0 0.00066 19.2 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 ETS75153.1 - 2.2e-07 30.6 0.2 0.00062 19.7 0.0 4.4 4 1 0 4 4 4 1 Kelch motif BTB PF00651.31 ETS75153.1 - 0.045 14.0 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain But2 PF09792.9 ETS75154.1 - 5.3e-29 101.5 0.5 1.9e-28 99.6 0.0 2.2 3 0 0 3 3 3 1 Ubiquitin 3 binding protein But2 C-terminal domain NGP1NT PF08153.12 ETS75155.1 - 6.1e-48 162.3 1.0 1e-47 161.5 1.0 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 ETS75155.1 - 1.6e-18 66.9 0.2 1.3e-13 51.1 0.0 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 ETS75155.1 - 7.2e-06 25.6 0.1 0.00013 21.5 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ETS75155.1 - 1.6e-05 24.9 0.0 5.6e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 ETS75155.1 - 0.0076 16.3 7.3 1 9.4 0.0 4.1 3 2 1 4 4 4 1 Dynamin family Arf PF00025.21 ETS75155.1 - 0.063 12.7 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family HMG_box PF00505.19 ETS75156.1 - 0.13 12.6 1.9 0.28 11.6 1.9 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box ABC2_membrane PF01061.24 ETS75157.1 - 1.2e-40 139.2 18.7 1.2e-40 139.2 18.7 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 ETS75157.1 - 6e-26 91.6 0.0 1.3e-25 90.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 ETS75157.1 - 4.8e-07 29.2 28.4 1.4e-05 24.4 28.4 2.5 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 ETS75157.1 - 9.6e-05 22.3 0.0 0.54 10.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 ETS75157.1 - 0.0086 16.0 0.0 0.25 11.2 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_29 PF13555.6 ETS75157.1 - 0.0095 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ETS75157.1 - 0.026 14.4 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 ETS75157.1 - 0.033 14.6 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ETS75157.1 - 0.043 14.1 0.0 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ETS75157.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 ETS75157.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ETS75157.1 - 0.079 13.5 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ETS75157.1 - 0.08 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 ETS75157.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 ETS75157.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family RecA PF00154.21 ETS75157.1 - 0.22 11.0 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein ABC2_membrane_2 PF12679.7 ETS75157.1 - 0.6 9.3 20.3 0.89 8.8 18.1 2.2 2 1 0 2 2 2 0 ABC-2 family transporter protein COX7C PF02935.16 ETS75158.1 - 0.44 10.8 3.7 8.2 6.8 0.3 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Aminotran_1_2 PF00155.21 ETS75159.1 - 6.8e-47 160.4 0.0 8.3e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ETS75159.1 - 1.9e-06 26.7 0.0 2.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 ETS75159.1 - 5.1e-06 25.5 0.0 6.4e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_5 PF00266.19 ETS75159.1 - 2.6e-05 23.4 0.0 4.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Alliinase_C PF04864.13 ETS75159.1 - 9.8e-05 21.4 0.3 0.0034 16.3 0.2 2.2 1 1 1 2 2 2 1 Allinase Beta_elim_lyase PF01212.21 ETS75159.1 - 0.00047 19.5 0.0 0.00081 18.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ETS75159.1 - 0.0036 16.7 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Asp PF00026.23 ETS75160.1 - 4.3e-63 213.6 6.1 7.1e-58 196.5 6.1 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 ETS75160.1 - 7.2e-06 26.6 3.6 0.017 15.7 0.3 3.2 2 1 1 3 3 3 2 Aspartyl protease TAXi_N PF14543.6 ETS75160.1 - 0.00033 21.0 4.1 0.11 12.7 0.2 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 ETS75160.1 - 0.003 18.1 0.7 0.38 11.3 0.1 2.8 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease GST_C PF00043.25 ETS75161.1 - 1.4e-08 34.8 0.0 3.2e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ETS75161.1 - 1.7e-07 31.4 0.1 9.9e-07 28.9 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ETS75161.1 - 2.9e-07 30.7 0.0 7.6e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ETS75161.1 - 3.2e-05 24.2 0.0 7.1e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS75161.1 - 0.00015 21.7 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ETS75161.1 - 0.00023 21.5 0.0 0.00039 20.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DAO PF01266.24 ETS75162.1 - 7.4e-39 134.3 0.0 8.5e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS75162.1 - 0.048 13.9 0.0 0.49 10.7 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS75162.1 - 0.11 12.5 0.1 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.16 ETS75163.1 - 4.9e-10 38.9 30.3 4.9e-10 38.9 30.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 ETS75163.1 - 4.9e-08 32.8 2.4 4.9e-08 32.8 2.4 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 ETS75163.1 - 1.4e-06 27.5 7.2 1.4e-06 27.5 7.2 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter ATPase_gene1 PF09527.10 ETS75163.1 - 1 9.6 10.6 3.8 7.8 0.6 3.5 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Methyltr_RsmB-F PF01189.17 ETS75165.1 - 0.022 14.4 0.1 0.048 13.3 0.0 1.5 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F Spt5_N PF11942.8 ETS75165.1 - 9.7 7.2 15.3 35 5.4 14.5 2.2 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal OB_NTP_bind PF07717.16 ETS75167.1 - 2.7e-11 43.7 0.0 1e-10 41.8 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ETS75167.1 - 1.3e-09 38.3 0.0 2.5e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 ETS75167.1 - 5.1e-09 36.4 0.0 9.7e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_22 PF13401.6 ETS75168.1 - 2.8e-06 27.6 0.0 5.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 ETS75168.1 - 3.4e-06 26.9 0.0 5.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ETS75168.1 - 0.00075 19.5 0.0 0.68 9.9 0.0 2.2 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ETS75168.1 - 0.0061 16.9 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 ETS75168.1 - 0.033 13.2 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 ETS75168.1 - 0.055 13.2 0.1 0.1 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain Terminase_6 PF03237.15 ETS75168.1 - 0.098 12.3 0.0 0.59 9.8 0.0 2.0 1 1 1 2 2 2 0 Terminase-like family Fungal_trans PF04082.18 ETS75171.1 - 1.2e-11 44.1 0.0 4.3e-11 42.4 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS75171.1 - 1.4e-06 28.3 11.5 2.7e-06 27.4 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavin_Reduct PF01613.18 ETS75172.1 - 4.4e-19 69.1 0.0 7.7e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 ETS75172.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Fungal_trans PF04082.18 ETS75174.1 - 2.4e-07 30.1 0.0 9.1e-07 28.2 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS75174.1 - 6.2e-07 29.4 9.5 1.2e-06 28.5 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FeS_assembly_P PF01883.19 ETS75175.1 - 5.5e-09 36.1 0.0 1.8e-08 34.4 0.0 1.9 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein GTP_EFTU PF00009.27 ETS75176.1 - 2.8e-45 154.3 0.0 4.2e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 ETS75176.1 - 1.1e-36 126.0 6.6 2.3e-36 125.1 6.6 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 ETS75176.1 - 6.8e-24 84.0 0.0 1.8e-23 82.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 ETS75176.1 - 2.6e-18 65.8 0.0 7.3e-18 64.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ETS75176.1 - 7.5e-09 35.9 0.1 2e-08 34.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 ETS75176.1 - 3.1e-07 30.4 0.1 1.8e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 ETS75176.1 - 0.00017 21.7 0.2 0.00033 20.7 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Thiolase_N PF00108.23 ETS75177.1 - 3.8e-93 311.6 3.4 6.2e-93 310.9 3.4 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ETS75177.1 - 1.1e-43 147.8 0.4 1.1e-43 147.8 0.4 2.0 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ETS75177.1 - 4.2e-05 23.3 0.2 4.2e-05 23.3 0.2 2.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ETS75177.1 - 0.11 12.4 3.7 0.49 10.3 0.0 3.0 3 1 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Sin3a_C PF16879.5 ETS75178.1 - 1.2e-69 235.2 3.4 1.4e-69 235.0 1.7 2.1 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein p450 PF00067.22 ETS75178.1 - 1.3e-50 172.5 0.0 3.6e-50 171.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome P450 PAH PF02671.21 ETS75178.1 - 7.5e-47 157.2 7.3 1.5e-17 63.4 0.0 4.2 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 ETS75178.1 - 1.8e-38 130.6 0.0 4.9e-38 129.2 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Pollen_allerg_1 PF01357.21 ETS75178.1 - 0.2 11.7 0.3 0.58 10.2 0.3 1.8 1 0 0 1 1 1 0 Pollen allergen TSP_NTD PF17804.1 ETS75178.1 - 8.6 6.6 17.9 0.11 12.8 1.5 3.9 4 1 1 5 5 5 0 Tail specific protease N-terminal domain Glyco_hydro_43 PF04616.14 ETS75179.1 - 3.3e-48 164.5 7.7 4.2e-48 164.1 7.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Dus PF01207.17 ETS75180.1 - 9.6e-42 143.1 0.0 2.1e-31 109.2 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) Torus PF16131.5 ETS75180.1 - 0.99 10.1 9.2 2.4 8.9 1.6 2.6 1 1 1 2 2 2 0 Torus domain zf-CCCH_4 PF18044.1 ETS75180.1 - 2.8 7.9 12.6 3.3 7.6 3.1 2.9 3 0 0 3 3 3 0 CCCH-type zinc finger zf-CCCH PF00642.24 ETS75180.1 - 3.2 7.8 13.1 4.5 7.3 1.8 3.3 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ETS75180.1 - 5 7.3 15.5 0.65 10.1 1.8 3.3 3 0 0 3 3 3 0 Zinc finger domain Kelch_1 PF01344.25 ETS75181.1 - 9.8e-44 146.7 16.5 8.6e-09 34.9 1.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 ETS75181.1 - 3.9e-42 141.6 16.5 2e-07 30.9 0.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 ETS75181.1 - 3.9e-40 135.4 20.2 1.8e-08 34.4 0.1 7.0 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.6 ETS75181.1 - 1e-39 134.3 16.6 3.8e-07 30.0 0.2 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 ETS75181.1 - 1.9e-34 116.3 16.1 7e-08 32.2 0.4 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 ETS75181.1 - 3.3e-34 116.0 18.2 1.4e-06 28.4 0.1 6.4 4 2 2 6 6 6 6 Kelch motif E1-E2_ATPase PF00122.20 ETS75183.1 - 2.9e-52 176.8 0.4 8.9e-52 175.2 0.4 1.9 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 ETS75183.1 - 6.2e-52 173.9 0.7 2.9e-13 50.0 0.0 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 ETS75183.1 - 3.5e-39 135.3 1.1 3.5e-39 135.3 1.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ETS75183.1 - 1.6e-06 28.0 0.6 3.3e-05 23.7 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ETS75183.1 - 0.058 13.5 0.2 0.34 11.0 0.1 2.2 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 ETS75183.1 - 0.099 13.0 0.1 0.24 11.8 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RelB_N PF18506.1 ETS75183.1 - 0.94 9.3 6.9 11 5.9 0.1 3.5 3 0 0 3 3 3 0 RelB Antitoxin alpha helical domain DUF2207 PF09972.9 ETS75183.1 - 1.9 7.1 3.2 14 4.2 0.0 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF1656 PF07869.12 ETS75183.1 - 3.2 7.8 6.1 22 5.2 4.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) PCI PF01399.27 ETS75184.1 - 2.6e-08 34.3 0.0 4.2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 ETS75184.1 - 0.048 13.6 0.5 0.1 12.5 0.5 1.5 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain RGS PF00615.19 ETS75185.1 - 4e-12 46.4 0.0 1.2e-08 35.3 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Ribosomal_L31e PF01198.19 ETS75186.1 - 3.8e-42 142.4 2.1 6.1e-42 141.7 2.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e M20_dimer PF07687.14 ETS75186.1 - 0.00077 19.4 0.0 0.0012 18.8 0.0 1.3 1 1 0 1 1 1 1 Peptidase dimerisation domain TrbC_Ftype PF09673.10 ETS75186.1 - 0.0024 17.9 0.1 0.0028 17.7 0.1 1.1 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin assembly protein DUF1104 PF06518.11 ETS75186.1 - 0.043 14.2 0.5 0.078 13.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) UQ_con PF00179.26 ETS75187.1 - 8.3e-49 164.8 0.0 1.1e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ETS75187.1 - 7.6e-06 25.7 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ETS75187.1 - 0.0022 18.2 0.0 0.0023 18.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 ETS75187.1 - 0.006 16.4 0.0 0.0092 15.8 0.0 1.3 1 0 0 1 1 1 1 UEV domain Pkinase PF00069.25 ETS75188.1 - 4.9e-61 206.4 0.0 7.1e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS75188.1 - 3.7e-30 105.1 0.0 9e-30 103.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS75188.1 - 1.6e-06 27.6 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ETS75188.1 - 0.0022 18.0 0.0 0.58 10.0 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ETS75188.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 ETS75188.1 - 0.088 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Choline_kinase PF01633.20 ETS75188.1 - 0.15 11.7 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 ETS75188.1 - 0.17 10.8 0.0 0.33 9.8 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain TFR_dimer PF04253.15 ETS75189.1 - 7.5e-26 90.6 0.0 1.3e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 ETS75189.1 - 7.7e-19 68.2 0.0 1.4e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ETS75189.1 - 3.7e-13 49.3 0.3 1.5e-12 47.4 0.1 2.0 2 0 0 2 2 2 1 PA domain TPR_12 PF13424.6 ETS75190.1 - 1.8e-54 181.9 43.2 1.6e-14 53.9 1.2 6.1 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 ETS75190.1 - 1.3e-52 174.3 24.8 5.8e-09 35.5 0.0 7.7 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 ETS75190.1 - 6.9e-11 41.4 24.9 0.047 13.7 0.7 8.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS75190.1 - 4.1e-08 33.0 32.6 3.3e-05 23.4 14.3 2.9 1 1 2 3 3 3 3 MalT-like TPR region NB-ARC PF00931.22 ETS75190.1 - 5.5e-08 32.3 0.0 2e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain TPR_2 PF07719.17 ETS75190.1 - 2.6e-07 30.2 20.1 0.017 15.2 0.2 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS75190.1 - 3.6e-07 30.3 14.5 0.1 12.8 2.2 5.8 1 1 4 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 ETS75190.1 - 1e-06 28.3 10.4 0.43 10.5 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 ETS75190.1 - 1.1e-06 29.1 3.8 2.6 8.8 0.1 5.9 5 2 0 5 5 5 2 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 ETS75190.1 - 3.4e-06 26.5 0.2 1.9e-05 24.0 0.2 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_4 PF07721.14 ETS75190.1 - 3.4e-06 27.1 11.8 21 6.1 0.0 7.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 ETS75190.1 - 3.8e-05 24.1 9.8 2 9.0 0.0 6.1 3 1 4 7 7 7 2 Tetratricopeptide repeat NACHT PF05729.12 ETS75190.1 - 0.00031 20.7 0.1 0.01 15.8 0.0 2.8 2 0 0 2 2 2 1 NACHT domain TPR_14 PF13428.6 ETS75190.1 - 0.0013 19.4 14.5 13 6.9 0.1 7.6 6 2 2 8 8 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 ETS75190.1 - 0.0018 18.2 9.1 28 4.8 0.2 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 ETS75190.1 - 0.0062 16.7 0.1 56 4.3 0.0 5.6 6 0 0 6 6 5 0 PPR repeat MIT PF04212.18 ETS75190.1 - 0.012 15.7 2.8 0.036 14.1 0.0 3.2 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain Urb2 PF10441.9 ETS75190.1 - 0.05 13.5 7.9 0.24 11.3 3.0 2.5 1 1 1 2 2 2 0 Urb2/Npa2 family HEAT_2 PF13646.6 ETS75190.1 - 0.053 13.9 0.1 4.3 7.8 0.0 2.8 2 0 0 2 2 2 0 HEAT repeats AAA_16 PF13191.6 ETS75190.1 - 0.088 13.2 1.9 3.4 8.0 0.0 3.5 3 1 0 3 3 3 0 AAA ATPase domain DUF1925 PF09094.11 ETS75190.1 - 0.089 13.1 16.6 5.2 7.5 0.1 5.8 2 1 4 6 6 5 0 Domain of unknown function (DUF1925) Fis1_TPR_C PF14853.6 ETS75190.1 - 0.15 12.2 5.1 3.1 7.9 0.0 4.5 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat DUF1842 PF08896.10 ETS75190.1 - 0.34 11.2 1.7 34 4.7 0.1 3.1 1 1 0 2 2 2 0 Domain of unknown function (DUF1842) TPR_17 PF13431.6 ETS75190.1 - 2.9 8.5 4.6 1e+02 3.6 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat RPN6_N PF18055.1 ETS75190.1 - 5.7 7.3 9.2 8.2 6.8 0.3 3.5 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain F-box-like PF12937.7 ETS75192.1 - 1.5e-09 37.6 3.3 3.1e-09 36.6 3.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS75192.1 - 1.8e-09 37.2 5.0 4.2e-09 36.1 5.0 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ETS75192.1 - 0.027 14.3 0.1 0.067 13.1 0.1 1.6 1 0 0 1 1 1 0 F-box SprT-like PF10263.9 ETS75193.1 - 2.5e-11 43.4 0.0 4.9e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 SprT-like family Peptidase_M50 PF02163.22 ETS75193.1 - 0.026 13.8 0.3 0.038 13.3 0.3 1.1 1 0 0 1 1 1 0 Peptidase family M50 DIOX_N PF14226.6 ETS75195.1 - 2.7e-26 92.6 0.0 5.3e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS75195.1 - 8.8e-14 51.8 0.0 1.7e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ETS75196.1 - 2.5e-18 66.9 0.1 5.6e-18 65.8 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS75196.1 - 2e-13 50.7 0.1 3.4e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 ETS75197.1 - 4.2e-26 91.7 25.6 7.6e-26 90.9 24.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily SpoVAB PF13782.6 ETS75197.1 - 1.1 9.5 4.7 2.4 8.5 0.4 2.7 2 1 0 2 2 2 0 Stage V sporulation protein AB TraL PF07178.11 ETS75197.1 - 2.2 8.8 6.8 0.33 11.5 0.6 2.9 3 0 0 3 3 3 0 TraL protein PepSY_TM_like_2 PF16357.5 ETS75197.1 - 3.1 7.7 5.3 0.25 11.3 0.4 1.6 2 0 0 2 2 2 0 Putative PepSY_TM-like Helo_like_N PF17111.5 ETS75199.1 - 2.9e-07 30.1 1.9 2.9e-07 30.1 1.9 3.0 2 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins ZapB PF06005.12 ETS75199.1 - 0.55 10.7 0.0 0.55 10.7 0.0 4.6 3 1 0 3 3 3 0 Cell division protein ZapB DUF1664 PF07889.12 ETS75199.1 - 0.66 10.0 14.3 30 4.7 2.1 5.1 4 2 0 4 4 4 0 Protein of unknown function (DUF1664) Rx_N PF18052.1 ETS75199.1 - 6.2 7.2 7.6 3.2 8.1 0.1 3.7 3 1 1 4 4 4 0 Rx N-terminal domain WD40 PF00400.32 ETS75200.1 - 5.9e-10 39.6 4.4 0.014 16.2 0.0 7.5 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS75200.1 - 6.8e-08 32.7 1.3 0.037 14.3 0.0 6.0 6 1 1 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 ETS75200.1 - 0.0002 21.0 0.1 0.00062 19.4 0.1 1.9 1 1 0 1 1 1 1 PQQ-like domain PD40 PF07676.12 ETS75200.1 - 0.014 15.3 0.1 7.7 6.6 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Cwf_Cwc_15 PF04889.12 ETS75200.1 - 5.2 6.7 11.0 1.1 8.9 1.5 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NAPRTase PF04095.16 ETS75201.1 - 6.7e-55 186.3 0.0 2.1e-29 102.8 0.3 2.2 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 ETS75201.1 - 1e-36 126.0 0.0 2.1e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain GIT_SHD PF08518.11 ETS75202.1 - 1e-22 79.4 7.8 1.9e-11 43.4 3.7 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT THP2 PF09432.10 ETS75202.1 - 0.0061 16.6 5.8 0.0061 16.6 5.8 2.2 1 1 1 2 2 2 1 Tho complex subunit THP2 PSII_Pbs27 PF13326.6 ETS75202.1 - 0.81 10.0 4.4 2 8.7 3.5 2.1 1 1 0 1 1 1 0 Photosystem II Pbs27 UPF0242 PF06785.11 ETS75202.1 - 1.6 8.8 44.0 5.2 7.1 21.8 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF1843 PF08898.10 ETS75202.1 - 2.5 8.7 7.3 0.73 10.4 1.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1843) Ssu72 PF04722.13 ETS75203.1 - 6.5e-84 280.3 0.0 7.7e-84 280.0 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein SH3_1 PF00018.28 ETS75204.1 - 7.3e-09 35.1 0.0 1.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ETS75204.1 - 1.5e-07 31.1 0.1 3.9e-07 29.8 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ETS75204.1 - 0.00015 21.4 0.0 0.0003 20.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain MARVEL PF01284.23 ETS75205.1 - 0.00012 22.2 23.6 0.00025 21.1 23.6 1.6 1 1 0 1 1 1 1 Membrane-associating domain TssN PF17555.2 ETS75205.1 - 2.3 7.5 8.0 3.3 7.0 8.0 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN CbiQ PF02361.16 ETS75205.1 - 9.2 5.8 12.6 13 5.3 12.6 1.2 1 0 0 1 1 1 0 Cobalt transport protein IBR PF01485.21 ETS75206.1 - 0.0003 20.9 20.9 0.0064 16.7 9.5 2.7 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain Nop14 PF04147.12 ETS75206.1 - 0.0072 14.6 14.2 0.011 14.0 14.2 1.2 1 0 0 1 1 1 1 Nop14-like family AP3D1 PF06375.11 ETS75206.1 - 0.021 15.1 13.1 0.047 13.9 13.1 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF4746 PF15928.5 ETS75206.1 - 0.04 13.3 5.7 0.078 12.4 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) BUD22 PF09073.10 ETS75206.1 - 0.085 12.2 17.6 0.17 11.2 17.6 1.4 1 0 0 1 1 1 0 BUD22 TypeIII_RM_meth PF12564.8 ETS75206.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit RNA_pol_3_Rpc31 PF11705.8 ETS75206.1 - 0.17 12.1 19.9 0.37 11.0 19.9 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 ETS75206.1 - 0.2 9.9 9.0 0.38 9.0 9.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Afi1 PF07792.12 ETS75206.1 - 0.48 10.9 11.2 1.3 9.5 11.2 1.7 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking YqhR PF11085.8 ETS75206.1 - 0.73 9.7 3.5 0.25 11.2 0.3 1.8 2 0 0 2 2 2 0 Conserved membrane protein YqhR DUF1168 PF06658.12 ETS75206.1 - 0.91 9.3 21.7 3.4 7.5 21.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Pox_Ag35 PF03286.14 ETS75206.1 - 2.1 8.1 17.2 3.9 7.2 17.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein tRNA_synt_1c_R2 PF04557.15 ETS75206.1 - 2.1 9.3 19.9 3.7 8.5 0.2 2.5 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Tim54 PF11711.8 ETS75206.1 - 2.2 7.0 10.9 3.9 6.2 10.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 ETS75206.1 - 2.4 6.8 5.9 5.3 5.7 5.9 1.5 1 0 0 1 1 1 0 Presenilin C1_4 PF07975.12 ETS75206.1 - 2.8 8.3 19.0 4.1 7.7 4.9 2.8 1 1 0 2 2 2 0 TFIIH C1-like domain zf-RING_4 PF14570.6 ETS75206.1 - 3.1 7.7 13.4 12 5.8 6.3 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain NPR3 PF03666.13 ETS75206.1 - 3.3 6.4 9.4 5.3 5.7 9.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Atrophin-1 PF03154.15 ETS75206.1 - 4.9 5.3 15.0 7.5 4.7 15.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family NARP1 PF12569.8 ETS75206.1 - 8.1 5.2 16.5 17 4.2 16.5 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3395 PF11875.8 ETS75207.1 - 7.9e-29 100.6 0.0 1.3e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 ETS75207.1 - 4.4e-08 33.1 0.0 8.5e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF2434 PF10361.9 ETS75207.1 - 0.079 11.9 0.2 0.12 11.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) DUF2090 PF09863.9 ETS75207.1 - 0.086 11.9 0.4 0.15 11.1 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) Fungal_trans PF04082.18 ETS75208.1 - 0.0028 16.7 0.2 0.0035 16.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_1 PF00175.21 ETS75210.1 - 1.8e-30 105.8 0.0 3e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ETS75210.1 - 2.2e-22 79.2 0.0 4e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ETS75210.1 - 1.2e-08 35.3 0.0 0.00059 20.0 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain PAF-AH_p_II PF03403.13 ETS75212.1 - 1.8e-56 191.3 0.0 7.9e-54 182.6 0.0 2.3 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ETS75212.1 - 2.8e-09 36.3 0.0 1e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Hydrolase_4 PF12146.8 ETS75212.1 - 4.3e-06 26.2 0.0 0.0096 15.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 ETS75212.1 - 2.5e-05 23.5 0.0 0.00061 18.9 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase DLH PF01738.18 ETS75212.1 - 0.0058 16.2 0.0 0.13 11.8 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 ETS75212.1 - 0.01 15.6 0.0 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 ETS75212.1 - 0.016 15.8 0.9 0.14 12.8 0.1 2.6 2 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS75212.1 - 0.067 12.8 0.2 2 8.0 0.0 2.6 3 0 0 3 3 3 0 alpha/beta hydrolase fold SnoaL_4 PF13577.6 ETS75213.1 - 8.3e-14 51.8 0.0 1.1e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain NmrA PF05368.13 ETS75214.1 - 1.4e-05 24.8 0.0 5.1e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 ETS75214.1 - 0.0085 16.0 0.0 0.053 13.4 0.0 2.0 1 1 1 2 2 2 1 NAD(P)H-binding Methyltransf_16 PF10294.9 ETS75215.1 - 2e-17 63.5 0.0 3.2e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 ETS75215.1 - 1e-05 26.1 0.0 2.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS75215.1 - 4.8e-05 24.0 0.0 0.00013 22.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS75215.1 - 5.7e-05 23.0 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS75215.1 - 0.0022 17.8 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 ETS75215.1 - 0.0079 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) MTS PF05175.14 ETS75215.1 - 0.0095 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 ETS75215.1 - 0.025 15.2 0.0 0.12 13.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 ETS75215.1 - 0.23 11.2 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF155 PF02582.14 ETS75216.1 - 9.6e-55 185.4 0.2 1.7e-54 184.6 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 ECSCR PF15820.5 ETS75216.1 - 0.077 12.8 0.2 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator GFO_IDH_MocA_C PF02894.17 ETS75217.1 - 5.1e-18 65.2 0.2 1.7e-17 63.5 0.3 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 ETS75217.1 - 2.1e-15 57.6 0.0 4.1e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MFS_1 PF07690.16 ETS75218.1 - 3.5e-32 111.7 30.6 4.7e-32 111.3 29.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Pox_A14 PF05767.12 ETS75218.1 - 0.59 10.3 4.8 5.5 7.2 0.1 3.2 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 p450 PF00067.22 ETS75220.1 - 1.6e-61 208.5 0.0 2e-61 208.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Xpo1 PF08389.12 ETS75220.1 - 0.029 14.4 0.1 0.049 13.7 0.1 1.3 1 0 0 1 1 1 0 Exportin 1-like protein FAD_binding_3 PF01494.19 ETS75221.1 - 1.8e-10 40.6 3.1 1.1e-09 38.0 1.8 2.7 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS75221.1 - 0.0031 16.8 1.0 0.22 10.7 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS75221.1 - 0.016 15.8 0.2 0.044 14.3 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS75221.1 - 0.036 13.3 0.4 0.43 9.8 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS75221.1 - 0.046 14.0 0.1 0.12 12.6 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Peptidase_S3 PF00944.19 ETS75222.1 - 0.0072 16.1 0.1 0.0089 15.8 0.1 1.1 1 0 0 1 1 1 1 Alphavirus core protein AMP-binding PF00501.28 ETS75223.1 - 6.7e-62 209.4 0.0 9.7e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 ETS75223.1 - 5.9e-07 28.5 0.0 9.2e-07 27.9 0.0 1.2 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 ETS75223.1 - 0.0028 18.6 0.1 0.013 16.5 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 ETS75223.1 - 0.015 15.6 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site DAO PF01266.24 ETS75225.1 - 1.1e-44 153.5 0.1 1.3e-44 153.3 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS75225.1 - 0.00044 20.4 0.3 0.0013 19.0 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ETS75225.1 - 0.12 11.5 0.3 0.15 11.2 0.3 1.3 1 1 0 1 1 1 0 FAD binding domain MCRA PF06100.11 ETS75225.1 - 0.14 10.9 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 MCRA family MFS_1 PF07690.16 ETS75226.1 - 9e-27 93.9 34.9 5.6e-24 84.7 8.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_5_1 PF06946.11 ETS75226.1 - 0.21 12.0 2.9 1.4 9.4 0.0 3.1 3 0 0 3 3 3 0 Bacteriophage A118-like holin, Hol118 Fungal_trans_2 PF11951.8 ETS75227.1 - 1.6e-07 30.5 0.0 2.5e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3483 PF11982.8 ETS75227.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) DUF1254 PF06863.12 ETS75230.1 - 2e-22 79.7 2.4 6.3e-22 78.1 0.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1254) DUF1214 PF06742.11 ETS75230.1 - 1.7e-20 73.5 0.4 2.4e-19 69.8 0.1 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1214) tRNA-synt_1b PF00579.25 ETS75232.1 - 6.5e-73 245.6 0.0 8.7e-73 245.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 ETS75232.1 - 4.8e-40 136.1 0.0 9.3e-40 135.2 0.0 1.5 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain DUF4110 PF13422.6 ETS75232.1 - 0.04 14.0 0.7 0.12 12.5 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) CybS PF05328.12 ETS75233.1 - 2.9e-47 159.7 0.0 4.8e-47 159.0 0.0 1.3 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Methyltransf_23 PF13489.6 ETS75234.1 - 2.3e-08 34.0 0.0 3.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS75234.1 - 0.00062 20.5 0.0 0.0024 18.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS75234.1 - 0.00065 20.4 0.0 0.0025 18.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS75234.1 - 0.0012 19.4 0.0 0.0023 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS75234.1 - 0.042 13.6 0.0 8.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Glyco_hydro_18 PF00704.28 ETS75235.1 - 1.6e-68 231.8 0.0 1.8e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Vps53_N PF04100.12 ETS75236.1 - 3.8e-102 342.1 0.0 6.9e-102 341.3 0.0 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 ETS75236.1 - 3.7e-07 29.7 3.4 7.7e-07 28.7 3.4 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 ETS75236.1 - 3.2e-05 23.9 0.0 6.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) RINT1_TIP1 PF04437.13 ETS75236.1 - 0.00019 20.5 1.1 0.0086 15.0 0.0 3.0 3 0 0 3 3 3 1 RINT-1 / TIP-1 family Sec6 PF06046.13 ETS75236.1 - 0.0002 19.9 0.1 0.0015 17.0 0.1 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec6 Zw10 PF06248.13 ETS75236.1 - 0.0033 16.0 1.4 0.0072 14.9 1.4 1.5 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Spc7 PF08317.11 ETS75236.1 - 0.01 14.8 2.0 0.023 13.6 2.0 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein VPS53_C PF16854.5 ETS75236.1 - 0.065 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus DUF5082 PF16888.5 ETS75236.1 - 0.22 11.8 2.4 0.49 10.7 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF2256 PF10013.9 ETS75237.1 - 0.0063 16.6 2.1 0.02 15.0 2.1 1.9 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) SpoIIIAH PF12685.7 ETS75238.1 - 3.5 7.4 10.1 7.8 6.3 10.1 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein FSA_C PF10479.9 ETS75238.1 - 7.8 4.5 17.4 11 4.0 17.4 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus NPR2 PF06218.11 ETS75239.1 - 2.8e-129 431.7 0.0 5.8e-129 430.7 0.0 1.5 1 1 0 1 1 1 1 Nitrogen permease regulator 2 NAD_binding_10 PF13460.6 ETS75240.1 - 4.8e-22 78.7 0.0 6.3e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS75240.1 - 0.00019 21.0 0.0 0.00037 20.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS75240.1 - 0.029 13.8 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ETS75240.1 - 0.041 13.4 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 ETS75240.1 - 0.14 11.3 0.0 0.38 9.8 0.0 1.7 1 1 0 1 1 1 0 RmlD substrate binding domain adh_short_C2 PF13561.6 ETS75241.1 - 2.7e-56 190.8 0.1 3e-56 190.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS75241.1 - 1.2e-44 152.1 0.0 1.6e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS75241.1 - 8.8e-09 35.5 0.1 1.5e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 ETS75241.1 - 0.086 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Fungal_trans PF04082.18 ETS75242.1 - 4.5e-19 68.5 0.0 7.4e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS75242.1 - 4.9e-05 23.4 11.6 8.4e-05 22.6 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 ETS75243.1 - 2.6e-14 52.6 0.1 1.6e-11 43.4 0.1 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ETS75243.1 - 3.6e-10 39.9 0.0 1e-09 38.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ETS75243.1 - 3.7e-06 26.3 0.0 0.095 11.8 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ETS75243.1 - 6.6e-05 22.9 0.0 0.00028 20.9 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 ETS75243.1 - 0.006 16.2 0.0 0.046 13.3 0.0 2.3 2 2 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS75243.1 - 0.0095 15.2 0.0 0.19 11.0 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ETS75243.1 - 0.22 11.6 0.0 1.1 9.3 0.0 2.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Acyl-CoA_dh_N PF02771.16 ETS75245.1 - 3.2e-07 31.0 0.0 4.5e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DUF3439 PF11921.8 ETS75245.1 - 0.029 14.3 2.2 0.04 13.9 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Acyl-CoA_dh_1 PF00441.24 ETS75246.1 - 7.6e-24 84.6 0.4 1.2e-23 84.0 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ETS75246.1 - 1.8e-09 37.7 0.0 3.1e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ETS75246.1 - 3.1e-07 30.7 0.0 5.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ETS75246.1 - 0.0012 19.5 0.3 0.0049 17.5 0.0 2.2 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Aldedh PF00171.22 ETS75247.1 - 3e-157 523.9 0.0 3.4e-157 523.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ETS75247.1 - 0.0091 15.5 0.0 1.6 8.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) adh_short_C2 PF13561.6 ETS75248.1 - 4e-42 144.4 0.0 4.8e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS75248.1 - 3.7e-36 124.4 0.0 4.8e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS75248.1 - 2.6e-08 34.0 0.1 3.7e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 KR domain AMP-binding PF00501.28 ETS75249.1 - 2.6e-91 306.3 0.0 3.3e-91 306.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS75249.1 - 2e-08 35.1 0.4 4.4e-08 34.0 0.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FMO-like PF00743.19 ETS75250.1 - 7e-12 44.5 0.0 1.4e-08 33.6 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ETS75250.1 - 5.3e-11 42.6 0.0 1.2e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS75250.1 - 1.4e-07 31.1 0.0 3.9e-06 26.3 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS75250.1 - 6.7e-06 25.5 0.0 0.034 13.4 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS75250.1 - 7.2e-05 22.5 0.0 0.0062 16.2 0.0 3.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS75250.1 - 0.00079 19.4 0.0 0.0064 16.5 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 ETS75250.1 - 0.0012 18.0 0.0 0.31 10.1 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 ETS75250.1 - 0.017 14.4 0.0 0.043 13.0 0.0 1.6 2 0 0 2 2 2 0 Thi4 family DUF1706 PF08020.11 ETS75250.1 - 0.085 12.8 0.0 3.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) Helicase_C PF00271.31 ETS75253.1 - 1.9e-14 54.0 0.4 8.5e-14 51.8 0.3 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 ETS75253.1 - 1e-06 29.0 0.0 2.5e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 ETS75253.1 - 0.0028 17.5 1.4 0.0031 17.3 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 ETS75253.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit APP_N PF02177.16 ETS75255.1 - 0.017 15.5 0.7 0.024 15.0 0.7 1.3 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding Glyco_hydro_70 PF02324.16 ETS75255.1 - 0.17 10.0 0.0 0.22 9.7 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 PALP PF00291.25 ETS75256.1 - 5.1e-41 141.0 0.1 5.7e-41 140.8 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.18 ETS75256.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 LytB protein Pyr_redox_2 PF07992.14 ETS75259.1 - 2e-47 161.9 1.8 2.3e-47 161.7 1.8 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS75259.1 - 2.7e-19 69.5 0.5 4.6e-17 62.3 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS75259.1 - 1.7e-17 63.6 0.9 4e-16 59.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS75259.1 - 1.1e-08 34.7 1.1 9.7e-05 21.8 0.1 3.1 2 1 1 3 3 3 2 FAD binding domain NAD_binding_7 PF13241.6 ETS75259.1 - 3.8e-06 27.3 0.0 0.0013 19.1 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 ETS75259.1 - 3.8e-05 23.8 0.1 0.044 14.0 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ETS75259.1 - 5.3e-05 22.7 0.6 0.019 14.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 ETS75259.1 - 0.00017 20.9 0.6 0.0007 18.9 0.1 2.1 2 1 1 3 3 3 1 Thi4 family DAO PF01266.24 ETS75259.1 - 0.00023 20.9 3.9 0.3 10.6 0.0 3.5 3 1 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 ETS75259.1 - 0.00042 19.6 0.7 0.38 9.9 0.1 3.2 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 ETS75259.1 - 0.0014 17.8 6.2 0.26 10.3 0.6 3.3 2 1 0 3 3 3 2 FAD binding domain GIDA PF01134.22 ETS75259.1 - 0.0035 16.5 5.9 0.59 9.1 0.4 4.1 3 2 1 4 4 4 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 ETS75259.1 - 0.009 16.0 0.2 0.59 10.1 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 ETS75259.1 - 0.029 14.4 0.2 14 5.8 0.0 3.1 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 ETS75259.1 - 0.036 12.9 0.1 0.47 9.2 0.0 2.2 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.14 ETS75259.1 - 0.049 12.3 1.6 2 7.0 0.3 3.1 2 2 1 3 3 3 0 HI0933-like protein Abhydrolase_3 PF07859.13 ETS75260.1 - 6.6e-52 176.4 0.0 8.2e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS75260.1 - 7.3e-09 35.0 0.4 4.3e-08 32.5 0.4 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ETS75260.1 - 5.8e-06 25.9 0.0 1.9e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 ETS75260.1 - 7e-05 21.8 0.0 9.1e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Esterase PF00756.20 ETS75260.1 - 0.012 15.3 0.4 0.61 9.7 0.4 2.3 1 1 0 1 1 1 0 Putative esterase FAD_binding_3 PF01494.19 ETS75261.1 - 7.5e-21 74.8 0.0 1.6e-20 73.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS75261.1 - 1.3e-06 27.9 0.0 4.2e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS75261.1 - 3.3e-05 24.0 0.1 7.5e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ETS75261.1 - 4.4e-05 24.0 0.0 0.00086 19.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS75261.1 - 0.0024 17.5 0.0 0.0075 15.9 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS75261.1 - 0.0048 15.7 0.0 0.0085 14.8 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 ETS75261.1 - 0.0055 15.8 0.0 0.013 14.6 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A SE PF08491.10 ETS75261.1 - 0.01 14.9 0.0 0.028 13.5 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase AlaDh_PNT_C PF01262.21 ETS75261.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 ETS75261.1 - 0.026 13.9 0.2 0.074 12.4 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 ETS75261.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M24 PF00557.24 ETS75262.1 - 7.3e-47 159.8 0.0 9e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 ETS75262.1 - 2e-21 76.0 7.5 2e-21 76.0 7.5 2.1 3 0 0 3 3 3 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 ETS75262.1 - 0.0006 19.8 4.4 0.0006 19.8 4.4 2.2 2 0 0 2 2 2 1 MYND finger Cornichon PF03311.14 ETS75263.1 - 6.9e-51 171.7 13.4 7.9e-51 171.5 13.4 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.32 ETS75264.1 - 3e-25 88.0 4.5 7.9e-06 26.5 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS75264.1 - 4.5e-15 55.7 0.3 5.3e-05 23.4 0.1 4.6 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ETS75264.1 - 0.00017 21.5 0.8 1.1 9.1 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 ETS75264.1 - 0.3 10.1 4.4 0.77 8.7 0.1 3.2 3 1 0 4 4 4 0 Coatomer WD associated region GMC_oxred_N PF00732.19 ETS75265.1 - 2.9e-63 214.0 0.0 5.3e-63 213.1 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS75265.1 - 2.2e-32 112.6 0.0 3.9e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ETS75265.1 - 8.7e-05 21.7 0.3 0.00012 21.2 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ETS75265.1 - 0.031 13.4 0.5 1.6 7.7 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 ETS75265.1 - 0.15 11.3 2.6 0.085 12.1 0.3 1.7 2 0 0 2 2 2 0 Thi4 family CBM_1 PF00734.18 ETS75266.1 - 2.6e-11 43.3 11.4 2.6e-11 43.3 11.4 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF2793 PF10983.8 ETS75266.1 - 0.0094 15.8 0.1 0.046 13.6 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2793) DUF2829 PF11195.8 ETS75267.1 - 1.8 8.9 6.5 15 5.9 6.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2829) MARVEL PF01284.23 ETS75268.1 - 0.0033 17.5 19.9 0.0049 16.9 19.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.11 ETS75268.1 - 0.062 13.2 19.8 2.4 8.0 15.1 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF4293 PF14126.6 ETS75268.1 - 0.14 12.4 6.9 0.08 13.2 4.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Tetraspanin PF00335.20 ETS75268.1 - 0.61 9.7 7.6 0.32 10.7 1.1 2.2 1 1 1 2 2 2 0 Tetraspanin family DUF1673 PF07895.11 ETS75268.1 - 1.1 9.0 5.5 0.29 10.8 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF4018 PF13210.6 ETS75268.1 - 3.8 7.2 11.3 0.32 10.8 6.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4018) RSRP PF17069.5 ETS75268.1 - 4.6 6.7 16.5 6.4 6.3 16.5 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 RDD PF06271.12 ETS75268.1 - 5.4 7.2 15.4 0.69 10.1 5.0 2.7 1 1 2 3 3 3 0 RDD family Cnn_1N PF07989.11 ETS75269.1 - 2.8e-20 72.2 9.2 2.8e-20 72.2 9.2 11.4 10 2 3 13 13 13 2 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 ETS75269.1 - 5.3e-08 33.0 9.3 5.3e-08 33.0 9.3 11.7 14 0 0 14 14 14 1 Micro-tubular organiser Mto1 C-term Mto2-binding region kleA_kleC PF17383.2 ETS75269.1 - 0.014 15.7 2.7 0.014 15.7 2.7 5.5 5 1 0 5 5 5 0 Uncharacterized KorC regulated protein A YabA PF06156.13 ETS75269.1 - 0.032 14.9 0.3 0.032 14.9 0.3 11.0 6 2 6 12 12 12 0 Initiation control protein YabA Shugoshin_N PF07558.11 ETS75269.1 - 4.2 7.3 29.0 9.4 6.2 0.9 8.1 8 0 0 8 8 8 0 Shugoshin N-terminal coiled-coil region FAD_binding_3 PF01494.19 ETS75270.1 - 6.6e-17 61.8 0.2 3.7e-11 42.9 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS75270.1 - 1.3e-05 25.3 0.1 3.2e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS75270.1 - 1.7e-05 24.3 0.0 0.17 11.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS75270.1 - 0.0019 17.5 0.0 0.1 11.8 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS75270.1 - 0.0039 17.7 0.1 0.35 11.4 0.0 3.2 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS75270.1 - 0.0082 15.2 0.0 0.51 9.3 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ETS75270.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 ETS75270.1 - 0.021 14.8 1.0 0.54 10.2 0.3 2.8 2 1 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 ETS75270.1 - 0.16 10.6 0.0 2.2 6.9 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein TraT PF05818.12 ETS75271.1 - 0.24 11.1 1.0 0.37 10.4 1.0 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF755 PF05501.11 ETS75271.1 - 1.6 9.0 14.8 2.4 8.4 14.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AP3D1 PF06375.11 ETS75271.1 - 6.1 7.1 11.8 9.7 6.4 11.8 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Acetyltransf_2 PF00797.17 ETS75272.1 - 9.1e-43 146.8 0.0 3.8e-37 128.4 0.0 2.8 1 1 0 2 2 2 2 N-acetyltransferase RNase_T PF00929.24 ETS75273.1 - 1.4e-07 32.2 0.0 2.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 ETS75273.1 - 0.00092 19.0 0.0 0.0046 16.7 0.0 2.1 2 0 0 2 2 2 1 3'-5' exonuclease GatB_N PF02934.15 ETS75275.1 - 1.5e-100 336.1 0.0 2e-100 335.7 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 ETS75275.1 - 3.9e-10 39.8 0.0 8.3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 GatB domain FA_desaturase PF00487.24 ETS75277.1 - 1.2e-17 64.7 12.8 1.2e-17 64.7 12.8 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ETS75277.1 - 7.8e-16 58.0 0.3 2.3e-15 56.5 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyoxalase_3 PF13468.6 ETS75278.1 - 3.6e-19 69.5 0.0 4.9e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain RNase_H PF00075.24 ETS75279.1 - 2.9e-23 82.6 0.0 6.5e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 RNase H zf-MYND PF01753.18 ETS75279.1 - 1.2e-07 31.7 7.5 3e-07 30.4 7.5 1.7 1 0 0 1 1 1 1 MYND finger RVT_3 PF13456.6 ETS75279.1 - 0.01 15.6 0.1 0.26 11.1 0.1 2.5 1 1 0 1 1 1 0 Reverse transcriptase-like SpoVAC_SpoVAEB PF03862.13 ETS75279.1 - 0.18 12.1 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 SpoVAC/SpoVAEB sporulation membrane protein zf-Mss51 PF13824.6 ETS75279.1 - 3.1 8.0 6.2 3.1 7.9 3.9 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Abhydrolase_2 PF02230.16 ETS75280.1 - 1e-19 71.3 0.1 1.3e-18 67.6 0.1 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 ETS75280.1 - 1e-05 25.1 0.0 3.1e-05 23.6 0.0 1.8 1 1 1 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ETS75280.1 - 0.0002 20.7 0.0 0.39 9.9 0.0 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 LIP PF03583.14 ETS75280.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.6 1 1 0 1 1 1 0 Secretory lipase DnaJ PF00226.31 ETS75281.1 - 1.4e-08 34.7 3.5 4.4e-08 33.1 0.3 2.3 1 1 1 2 2 2 1 DnaJ domain DEAD PF00270.29 ETS75282.1 - 5.1e-43 146.9 0.0 7.2e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS75282.1 - 1.6e-27 96.0 0.4 1.2e-26 93.3 0.3 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS75282.1 - 0.0003 20.9 0.0 0.00046 20.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ETS75282.1 - 0.097 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DSPc PF00782.20 ETS75283.1 - 8.2e-28 96.9 0.0 9.7e-28 96.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 ETS75283.1 - 0.053 13.6 0.0 0.086 13.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 ETS75283.1 - 0.088 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain Sulfotransfer_4 PF17784.1 ETS75284.1 - 8.4e-51 172.8 0.1 9.8e-51 172.6 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ETS75284.1 - 0.13 12.7 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase family Seryl_tRNA_N PF02403.22 ETS75285.1 - 1 9.6 3.2 0.67 10.2 0.9 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 ETS75285.1 - 1.3 9.1 6.6 0.86 9.7 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MCPsignal PF00015.21 ETS75285.1 - 2.7 7.8 9.2 3.7 7.3 7.4 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain tRNA_m1G_MT PF01746.21 ETS75286.1 - 4.2e-26 91.9 0.0 3.9e-18 65.9 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase MutS_V PF00488.21 ETS75287.1 - 3.2e-83 278.4 0.4 5.2e-83 277.7 0.4 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ETS75287.1 - 1.8e-37 129.5 0.8 1.8e-37 129.5 0.8 2.2 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.17 ETS75287.1 - 2.3e-24 86.2 0.1 8.3e-24 84.4 0.1 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 ETS75287.1 - 6.5e-20 71.3 1.6 3.7e-19 68.9 0.8 2.7 3 0 0 3 3 3 1 MutS family domain IV MutS_I PF01624.20 ETS75287.1 - 1.2e-18 67.4 0.0 8e-18 64.7 0.0 2.2 2 0 0 2 2 2 1 MutS domain I SUR7 PF06687.12 ETS75287.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 SUR7/PalI family ArdA PF07275.11 ETS75287.1 - 0.15 12.7 0.1 0.46 11.0 0.1 1.9 1 0 0 1 1 1 0 Antirestriction protein (ArdA) Com_YlbF PF06133.11 ETS75287.1 - 0.57 10.8 5.2 9.5 6.9 0.7 3.4 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA PAN_4 PF14295.6 ETS75288.1 - 4e-05 23.4 19.8 0.02 14.8 0.6 3.7 3 0 0 3 3 3 3 PAN domain PAN_2 PF08276.11 ETS75288.1 - 0.00071 19.6 12.6 0.0051 16.9 0.8 3.7 3 0 0 3 3 3 2 PAN-like domain PAN_3 PF08277.12 ETS75288.1 - 1.2 9.0 6.9 8.5 6.3 0.2 3.0 3 0 0 3 3 3 0 PAN-like domain adh_short PF00106.25 ETS75289.1 - 7.9e-30 103.8 0.0 1.2e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS75289.1 - 1.3e-19 70.7 0.0 3.3e-19 69.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FMN_red PF03358.15 ETS75292.1 - 1.9e-12 47.2 0.0 3.7e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ETS75292.1 - 1.6e-06 28.0 0.0 2.8e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Flavodoxin-like fold UDPGT PF00201.18 ETS75293.1 - 2.8e-06 26.4 0.0 4.2e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase AAA_35 PF14516.6 ETS75293.1 - 0.043 12.6 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain MFS_1 PF07690.16 ETS75294.1 - 3.8e-30 105.0 34.1 3.8e-30 105.0 34.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS75294.1 - 1.2e-11 44.2 11.3 1.2e-11 44.2 11.3 2.4 2 1 2 4 4 4 1 Sugar (and other) transporter CorA PF01544.18 ETS75294.1 - 0.37 10.1 2.6 0.68 9.2 2.6 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein EMP70 PF02990.16 ETS75294.1 - 0.56 8.8 10.8 0.34 9.5 3.0 2.6 2 1 0 2 2 2 0 Endomembrane protein 70 MFS_1 PF07690.16 ETS75295.1 - 3.7e-36 124.8 46.2 1.7e-35 122.6 43.5 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS75295.1 - 3.5e-06 25.7 16.4 4.7e-06 25.3 16.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 ETS75296.1 - 5.1e-36 124.4 0.0 6.9e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_59 PF02057.15 ETS75297.1 - 2.2e-17 63.3 0.2 3.5e-17 62.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 ETS75297.1 - 2.7e-14 53.5 3.5 4.6e-13 49.5 0.1 2.3 1 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 ETS75297.1 - 4.4e-14 52.5 3.8 1.7e-13 50.6 3.8 2.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 ETS75297.1 - 3.1e-11 42.9 0.5 6.8e-11 41.7 0.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_76 PF03663.14 ETS75298.1 - 2.4e-153 511.0 20.1 2.7e-153 510.8 20.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 ETS75298.1 - 0.012 14.7 8.1 0.27 10.2 0.3 3.0 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 DUF4385 PF14328.6 ETS75299.1 - 2.2e-56 190.0 3.8 2.9e-56 189.6 3.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) Tim17 PF02466.19 ETS75300.1 - 6.1e-06 26.6 6.1 1.1e-05 25.8 6.1 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TraT PF05818.12 ETS75300.1 - 0.41 10.3 4.7 0.61 9.7 4.7 1.3 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein UCH PF00443.29 ETS75301.1 - 2.5e-37 128.8 0.1 5.2e-37 127.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ETS75301.1 - 0.0083 15.8 10.9 0.16 11.6 10.9 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 ETS75301.1 - 0.059 12.8 3.2 0.34 10.4 0.1 2.7 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Methyltransf_16 PF10294.9 ETS75302.1 - 4.9e-17 62.2 0.0 1.2e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 ETS75302.1 - 7.6e-07 28.8 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ETS75302.1 - 0.00014 21.5 0.1 0.00025 20.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ETS75302.1 - 0.0082 16.8 0.2 0.018 15.8 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 ETS75302.1 - 0.0086 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 ETS75302.1 - 0.024 14.4 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ETS75302.1 - 0.028 14.2 0.2 0.076 12.8 0.2 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 ETS75302.1 - 0.029 14.2 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Hydrophobin_2 PF06766.11 ETS75303.1 - 2.1e-25 88.4 10.7 2.6e-25 88.1 10.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin HET PF06985.11 ETS75305.1 - 4.6e-14 53.0 0.0 5.1e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.19 ETS75306.1 - 1.9e-18 66.9 0.3 1.1e-16 61.1 0.3 2.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ETS75306.1 - 7.6e-07 29.3 0.0 1.7e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS75306.1 - 0.00029 20.2 0.0 0.00045 19.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS75306.1 - 0.0013 17.9 0.1 0.002 17.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ETS75306.1 - 0.0044 16.1 0.5 0.007 15.5 0.0 1.7 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 ETS75306.1 - 0.0051 16.4 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS75306.1 - 0.0056 17.2 0.1 0.013 16.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS75306.1 - 0.0072 15.6 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ETS75306.1 - 0.0084 16.4 0.2 0.095 13.0 0.1 2.4 2 1 0 2 2 2 1 TrkA-N domain SE PF08491.10 ETS75306.1 - 0.012 14.7 0.0 0.22 10.5 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase AdoHcyase_NAD PF00670.21 ETS75306.1 - 0.2 11.7 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GMC_oxred_C PF05199.13 ETS75307.1 - 2.8e-34 118.7 0.0 3.5e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 ETS75308.1 - 3.5e-07 29.9 0.0 4.1e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 ETS75309.1 - 1.7e-35 122.8 0.0 2e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 ETS75309.1 - 1.1e-06 28.1 0.4 0.00014 21.2 0.1 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 ETS75309.1 - 1.3e-05 25.3 0.5 2.8e-05 24.2 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS75309.1 - 3e-05 23.3 0.2 8.6e-05 21.8 0.1 1.8 2 1 1 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 ETS75309.1 - 3.5e-05 23.0 0.0 4.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 ETS75309.1 - 4e-05 23.4 0.1 8e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS75309.1 - 0.00013 21.3 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS75309.1 - 0.0039 16.0 0.0 0.0053 15.5 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 ETS75309.1 - 0.004 16.5 0.1 0.016 14.5 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ETS75309.1 - 0.064 12.1 0.0 0.081 11.8 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 ETS75309.1 - 0.066 13.2 0.1 0.21 11.6 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 ETS75309.1 - 0.18 12.4 0.1 0.86 10.2 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase LysM PF01476.20 ETS75311.1 - 3e-08 33.6 0.0 0.19 11.9 0.0 3.4 3 0 0 3 3 3 3 LysM domain Glyco_hydro_18 PF00704.28 ETS75312.1 - 2.6e-67 227.8 0.1 4.5e-67 227.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ETS75312.1 - 2.2e-08 34.4 9.2 2.2e-08 34.4 9.2 5.8 6 0 0 6 6 6 2 Chitin recognition protein Glyco_hydro_85 PF03644.13 ETS75312.1 - 0.002 17.6 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 LysM PF01476.20 ETS75314.1 - 0.018 15.1 0.1 1.2 9.3 0.0 2.6 3 0 0 3 3 3 0 LysM domain Nop PF01798.18 ETS75315.1 - 8.6e-82 274.0 0.3 1.6e-81 273.2 0.3 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 ETS75315.1 - 1.5e-17 63.7 0.0 1.5e-17 63.7 0.0 2.5 3 0 0 3 3 3 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 ETS75315.1 - 1.2 9.2 25.3 2.1 8.4 25.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Coilin_N PF15862.5 ETS75315.1 - 1.2 8.9 16.9 2.3 8.0 16.9 1.5 1 0 0 1 1 1 0 Coilin N-terminus Sugar_tr PF00083.24 ETS75316.1 - 7.1e-113 377.8 19.3 8.9e-113 377.5 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS75316.1 - 2.9e-24 85.7 33.6 7.1e-16 58.1 6.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS75316.1 - 0.0019 16.8 6.2 0.0019 16.8 6.2 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein DUF615 PF04751.14 ETS75316.1 - 0.21 11.5 0.9 11 6.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF615) DAO PF01266.24 ETS75317.1 - 7.3e-40 137.6 0.3 9.1e-40 137.3 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS75317.1 - 2.6e-05 24.3 0.3 9.2e-05 22.6 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 ETS75317.1 - 0.03 13.1 0.1 0.044 12.6 0.1 1.2 1 0 0 1 1 1 0 MCRA family MFS_1 PF07690.16 ETS75318.1 - 3.5e-09 36.1 5.9 3.8e-09 35.9 5.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 ETS75319.1 - 2.9e-18 65.9 0.1 4.8e-18 65.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GalKase_gal_bdg PF10509.9 ETS75319.1 - 0.064 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Pkinase PF00069.25 ETS75320.1 - 1e-52 179.1 0.0 1.6e-52 178.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS75320.1 - 9.1e-30 103.8 0.0 1.5e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS75320.1 - 1.1e-05 24.9 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ETS75320.1 - 0.0034 16.2 0.3 0.0069 15.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ETS75320.1 - 0.086 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 ETS75321.1 - 0.00014 21.3 0.1 0.087 12.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 ETS75321.1 - 0.00018 21.0 0.0 0.0006 19.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain DUF4624 PF15417.6 ETS75322.1 - 0.012 15.4 0.1 0.031 14.1 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4624) DUF2433 PF10360.9 ETS75322.1 - 0.057 13.5 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) tRNA_anti-like PF12869.7 ETS75322.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 tRNA_anti-like FSA_C PF10479.9 ETS75322.1 - 0.86 7.7 4.3 1.5 6.9 4.3 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus F5_F8_type_C PF00754.25 ETS75323.1 - 0.0015 18.6 2.5 0.0022 18.1 0.2 2.3 2 0 0 2 2 2 1 F5/8 type C domain Trehalase PF01204.18 ETS75323.1 - 0.0059 15.5 1.7 0.011 14.7 1.7 1.4 1 1 0 1 1 1 1 Trehalase adh_short PF00106.25 ETS75325.1 - 8e-14 51.6 0.1 6.7e-11 42.0 0.0 2.9 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS75325.1 - 2.1e-09 37.3 0.1 3.3e-07 30.1 0.1 2.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS75325.1 - 1.3e-06 28.4 0.1 3.7e-06 27.0 0.1 1.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 ETS75325.1 - 7.4e-05 22.3 0.0 0.00057 19.4 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.25 ETS75325.1 - 0.055 12.9 0.0 0.15 11.4 0.0 1.7 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Na_Ca_ex_C PF16494.5 ETS75325.1 - 0.071 13.6 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain Glyco_transf_5 PF08323.11 ETS75325.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Starch synthase catalytic domain COesterase PF00135.28 ETS75326.1 - 1.2e-84 285.0 0.3 2e-79 267.8 0.2 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS75326.1 - 1.6e-07 31.4 0.0 2.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold JSRP PF15312.6 ETS75326.1 - 0.087 12.8 0.1 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Fungal_trans_2 PF11951.8 ETS75327.1 - 2.2e-05 23.5 0.3 4.4e-05 22.5 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_1 PF01979.20 ETS75328.1 - 7.7e-24 84.6 0.0 2.5e-23 82.9 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS75328.1 - 2.9e-14 53.4 1.1 3.5e-09 36.7 0.2 3.0 2 2 1 3 3 3 2 Amidohydrolase family adh_short PF00106.25 ETS75329.1 - 2.2e-24 86.0 0.0 4.5e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS75329.1 - 2.6e-19 69.7 0.0 3.9e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RepB_primase PF16793.5 ETS75329.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 RepB DNA-primase from phage plasmid DUF3425 PF11905.8 ETS75330.1 - 1.4e-21 76.7 1.1 2.9e-21 75.7 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) PDEase_II PF02112.15 ETS75330.1 - 0.043 12.9 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Abhydrolase_6 PF12697.7 ETS75331.1 - 8.8e-08 33.0 1.1 9.4e-07 29.7 0.1 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 ETS75331.1 - 2.8e-06 27.1 0.3 1.7e-05 24.5 0.3 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 ETS75331.1 - 2.8e-05 23.9 0.1 4.1e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1100 PF06500.11 ETS75331.1 - 0.0015 17.4 0.0 0.002 17.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) BAAT_C PF08840.11 ETS75331.1 - 0.0036 17.3 0.0 0.0068 16.4 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 ETS75331.1 - 0.007 15.1 0.1 0.012 14.3 0.1 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 ETS75331.1 - 0.044 12.7 0.0 1.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase enzyme UPF0020 PF01170.18 ETS75331.1 - 0.088 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Metallophos_2 PF12850.7 ETS75331.1 - 0.096 12.9 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Hydrolase_4 PF12146.8 ETS75331.1 - 0.15 11.3 0.0 2.8 7.2 0.0 2.6 2 1 1 3 3 3 0 Serine aminopeptidase, S33 FAD_binding_4 PF01565.23 ETS75332.1 - 2.4e-16 59.7 0.9 3.6e-16 59.2 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 ETS75332.1 - 1.4e-10 41.1 0.4 2.8e-10 40.1 0.4 1.6 1 0 0 1 1 1 1 Berberine and berberine like NmrA PF05368.13 ETS75333.1 - 1e-14 54.7 0.0 1.2e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS75333.1 - 6e-05 23.0 0.0 9.5e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding p450 PF00067.22 ETS75334.1 - 1.1e-70 238.7 0.0 1.4e-70 238.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ACR_tran PF00873.19 ETS75334.1 - 0.037 11.7 0.0 0.049 11.3 0.0 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family NADHdh_A3 PF14987.6 ETS75335.1 - 0.69 10.3 3.6 9.2 6.7 0.1 3.0 2 1 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 HET PF06985.11 ETS75336.1 - 3.7e-30 105.2 0.9 3.7e-30 105.2 0.9 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Mucin PF01456.17 ETS75337.1 - 0.0011 19.0 70.2 0.0067 16.4 33.3 2.3 2 0 0 2 2 2 2 Mucin-like glycoprotein Ecl1 PF12855.7 ETS75337.1 - 0.64 11.2 21.8 0.86 10.7 5.5 2.2 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins NAM-associated PF14303.6 ETS75337.1 - 1.8 9.2 15.7 0.12 13.1 2.0 2.1 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Sporozoite_P67 PF05642.11 ETS75337.1 - 9.7 4.1 41.0 0.033 12.3 11.7 2.1 1 1 0 2 2 2 0 Sporozoite P67 surface antigen Ribonuclease PF00545.20 ETS75338.1 - 4e-08 33.9 0.0 5.5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 ribonuclease Tmemb_14 PF03647.13 ETS75339.1 - 1.3e-24 86.7 3.5 1.5e-24 86.5 3.5 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Gram_pos_anchor PF00746.21 ETS75339.1 - 0.17 11.8 0.0 0.17 11.8 0.0 3.0 4 0 0 4 4 4 0 LPXTG cell wall anchor motif Phage_holin_2_4 PF16082.5 ETS75339.1 - 1.1 9.0 7.8 1.5 8.6 0.2 2.8 1 1 1 3 3 3 0 Bacteriophage holin family, superfamily II-like Peptidase_C97 PF05903.14 ETS75340.1 - 0.0059 16.5 0.1 0.0096 15.8 0.1 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain ADH_zinc_N PF00107.26 ETS75341.1 - 1.7e-09 37.8 0.0 2.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS75341.1 - 1.2e-05 25.2 0.0 2.9e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ETS75341.1 - 0.0014 19.6 0.0 0.0025 18.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ras PF00071.22 ETS75344.1 - 4.7e-47 159.6 0.0 7.9e-47 158.9 0.0 1.4 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.7 ETS75344.1 - 5.2e-32 110.3 0.7 2.1e-11 44.3 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS75344.1 - 3.2e-24 85.0 10.4 4e-05 24.1 0.0 4.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS75344.1 - 1.4e-19 69.9 3.9 2.9e-05 24.2 0.1 5.6 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS75344.1 - 7.5e-18 62.8 4.2 0.22 12.2 0.0 7.1 7 0 0 7 7 6 5 Ankyrin repeat Ank PF00023.30 ETS75344.1 - 4.1e-17 61.8 12.6 0.024 15.1 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeat Roc PF08477.13 ETS75344.1 - 2.9e-14 53.3 0.0 1.1e-13 51.5 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF676 PF05057.14 ETS75344.1 - 0.0027 17.2 0.1 0.015 14.8 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Arf PF00025.21 ETS75344.1 - 0.009 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family PGAP1 PF07819.13 ETS75344.1 - 0.0097 15.6 0.0 0.022 14.5 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 ETS75344.1 - 0.035 13.4 0.0 0.38 10.0 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 RsgA_GTPase PF03193.16 ETS75344.1 - 0.066 13.1 0.0 2.7 7.9 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 ETS75344.1 - 0.11 12.8 0.3 0.75 10.2 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.20 ETS75344.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit NACHT PF05729.12 ETS75344.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ADC PF06314.11 ETS75345.1 - 0.00021 21.0 0.0 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Glycoprot_B_PH1 PF17416.2 ETS75345.1 - 0.17 11.5 0.6 5.2 6.6 0.1 2.1 1 1 1 2 2 2 0 Herpesvirus Glycoprotein B GMC_oxred_N PF00732.19 ETS75346.1 - 6.2e-55 186.7 0.0 8.6e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS75346.1 - 2.3e-33 115.7 0.1 5.5e-33 114.5 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_3 PF01494.19 ETS75346.1 - 7.9e-18 64.8 0.3 6.9e-10 38.7 0.0 3.4 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 ETS75346.1 - 0.00011 21.5 0.5 0.00026 20.3 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS75346.1 - 0.00022 20.4 0.0 0.0023 17.0 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ETS75346.1 - 0.00056 20.1 0.0 0.0016 18.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS75346.1 - 0.013 15.4 0.4 0.22 11.5 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding SE PF08491.10 ETS75346.1 - 0.014 14.5 0.0 0.074 12.1 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Thi4 PF01946.17 ETS75346.1 - 0.029 13.6 0.3 0.077 12.2 0.1 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 ETS75346.1 - 0.037 13.1 0.1 0.33 10.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 ETS75346.1 - 0.059 12.9 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS75346.1 - 0.091 12.0 0.1 0.27 10.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS75346.1 - 0.13 10.9 0.0 0.39 9.4 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 ETS75346.1 - 0.27 11.8 1.5 19 5.9 0.0 3.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M35 PF02102.15 ETS75347.1 - 3.3e-63 213.7 20.9 4e-63 213.5 20.9 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 ETS75347.1 - 3.7e-36 124.8 3.9 3.7e-36 124.8 3.9 2.2 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase TOBE_2 PF08402.10 ETS75347.1 - 0.047 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 TOBE domain Big_4 PF07532.11 ETS75347.1 - 0.071 12.9 0.0 0.26 11.0 0.0 2.0 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) Peptidase_M61 PF05299.12 ETS75349.1 - 2e-05 24.9 0.3 6.4e-05 23.3 0.3 1.8 1 1 0 1 1 1 1 M61 glycyl aminopeptidase DUF2235 PF09994.9 ETS75350.1 - 3.5e-72 243.2 0.0 4.7e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) NACHT PF05729.12 ETS75351.1 - 1.8e-09 37.7 0.0 5.6e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS75351.1 - 0.00015 22.2 0.1 0.001 19.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 ETS75351.1 - 0.0035 17.7 0.0 0.37 11.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 ETS75351.1 - 0.0096 16.2 0.0 0.088 13.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ETS75351.1 - 0.021 15.4 0.0 0.21 12.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ETS75351.1 - 0.037 14.6 0.0 0.094 13.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 ETS75351.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NUMOD1 PF07453.13 ETS75351.1 - 0.066 13.5 1.8 0.066 13.5 0.0 2.0 2 0 0 2 2 2 0 NUMOD1 domain DUF3328 PF11807.8 ETS75352.1 - 1.1e-15 58.0 0.2 1.4e-15 57.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 ETS75353.1 - 6e-21 75.2 1.1 1.4e-20 74.0 0.2 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 ETS75354.1 - 1.6e-16 60.8 0.0 1.7e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 ETS75355.1 - 3.9e-30 105.3 0.3 5.8e-30 104.7 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Spin-Ssty PF02513.17 ETS75356.1 - 1.7e-11 43.7 3.0 3.2 7.6 0.0 6.0 5 1 1 6 6 6 6 Spin/Ssty Family Phage_CI_C PF16452.5 ETS75356.1 - 0.00047 20.4 0.4 1.1 9.6 0.0 3.0 1 1 2 3 3 3 2 Bacteriophage CI repressor C-terminal domain Chromo PF00385.24 ETS75356.1 - 0.084 12.8 19.7 39 4.3 0.1 5.8 1 1 2 3 3 3 0 Chromo (CHRromatin Organisation MOdifier) domain Amastin PF07344.11 ETS75357.1 - 0.0016 18.3 9.5 0.003 17.4 9.5 1.4 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4538 PF15061.6 ETS75357.1 - 0.12 12.1 0.6 0.31 10.8 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Bee_toxin PF17454.2 ETS75357.1 - 1.3 9.2 4.5 0.57 10.2 0.7 2.4 2 0 0 2 2 2 0 Honey bee toxin Acyl_transf_3 PF01757.22 ETS75358.1 - 2.1e-16 59.9 27.5 4.3e-16 58.9 27.5 1.5 1 1 0 1 1 1 1 Acyltransferase family DUF1624 PF07786.12 ETS75358.1 - 8.5e-05 22.2 2.2 8.5e-05 22.2 2.2 2.9 2 2 0 3 3 3 1 Protein of unknown function (DUF1624) MMgT PF10270.9 ETS75358.1 - 0.28 11.6 1.4 0.52 10.7 0.0 2.1 3 0 0 3 3 3 0 Membrane magnesium transporter LrgB PF04172.16 ETS75359.1 - 0.069 12.7 2.3 0.1 12.1 2.3 1.1 1 0 0 1 1 1 0 LrgB-like family GTA_holin_3TM PF11351.8 ETS75360.1 - 1.3 9.5 4.2 1.7 9.2 0.0 3.0 3 0 0 3 3 3 0 Holin of 3TMs, for gene-transfer release DUF3278 PF11683.8 ETS75360.1 - 2.3 8.3 4.8 12 6.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) DUF3328 PF11807.8 ETS75361.1 - 1.1e-20 74.4 0.0 1.7e-20 73.8 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans PF04082.18 ETS75362.1 - 6.5e-05 22.1 0.8 9.3e-05 21.6 0.7 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S10 PF00450.22 ETS75363.1 - 1.7e-83 281.4 0.0 2.3e-83 280.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase ABC_membrane PF00664.23 ETS75364.1 - 5.3e-40 137.8 28.9 5.1e-27 95.2 13.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ETS75364.1 - 9.6e-40 136.3 0.1 8.4e-20 71.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ETS75364.1 - 6.5e-14 52.4 1.9 9.1e-05 22.4 0.1 4.3 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETS75364.1 - 7.6e-13 48.4 1.8 4.7e-05 22.9 0.0 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ETS75364.1 - 4.5e-08 32.7 0.5 0.0012 18.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ETS75364.1 - 7.9e-08 32.7 0.0 0.0066 16.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ETS75364.1 - 1.3e-07 32.1 2.5 0.011 16.1 0.5 2.7 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 ETS75364.1 - 1.1e-05 25.6 0.4 0.01 16.0 0.0 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain T2SSE PF00437.20 ETS75364.1 - 1.2e-05 24.5 0.3 0.15 11.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_15 PF13175.6 ETS75364.1 - 2.8e-05 24.0 0.2 0.0074 16.0 0.0 2.4 3 0 0 3 3 2 1 AAA ATPase domain AAA_18 PF13238.6 ETS75364.1 - 7.7e-05 23.2 0.0 0.079 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ETS75364.1 - 0.00012 22.0 0.0 0.3 11.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ETS75364.1 - 0.00012 22.1 0.1 0.12 12.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 ETS75364.1 - 0.0003 20.2 0.1 0.39 10.0 0.0 2.6 3 0 0 3 3 2 2 FtsK/SpoIIIE family AAA_23 PF13476.6 ETS75364.1 - 0.0007 20.2 0.2 1.7 9.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 ETS75364.1 - 0.0023 17.4 0.1 0.48 9.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynamin_N PF00350.23 ETS75364.1 - 0.0042 17.2 0.9 2.9 7.9 0.1 2.4 2 0 0 2 2 2 2 Dynamin family RNA_helicase PF00910.22 ETS75364.1 - 0.0048 17.3 0.1 2.8 8.4 0.0 2.8 3 0 0 3 3 2 1 RNA helicase TrwB_AAD_bind PF10412.9 ETS75364.1 - 0.0056 15.6 0.0 1.8 7.4 0.0 2.6 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 ETS75364.1 - 0.015 14.9 0.6 0.28 10.7 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 ETS75364.1 - 0.02 14.1 0.0 0.25 10.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 ETS75364.1 - 0.024 14.5 0.5 0.91 9.4 0.2 2.8 2 0 0 2 2 2 0 NTPase SbcCD_C PF13558.6 ETS75364.1 - 0.025 14.8 1.2 9.3 6.6 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 ETS75364.1 - 0.027 14.1 0.0 0.94 9.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ETS75364.1 - 0.028 13.7 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_10 PF12846.7 ETS75364.1 - 0.042 12.8 0.0 0.46 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain Rad17 PF03215.15 ETS75364.1 - 0.046 13.6 0.6 8.3 6.3 0.0 2.7 3 0 0 3 3 2 0 Rad17 P-loop domain DUF815 PF05673.13 ETS75364.1 - 0.073 12.2 0.2 1 8.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 ETS75364.1 - 0.077 13.2 0.0 6 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 ETS75364.1 - 0.13 11.3 0.0 4 6.3 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 ETS75364.1 - 0.14 11.3 0.0 13 4.9 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit DUF3290 PF11694.8 ETS75364.1 - 0.17 11.8 8.3 3.7 7.5 1.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) ATPase_2 PF01637.18 ETS75364.1 - 0.18 11.7 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 ETS75364.1 - 0.19 10.9 0.0 11 5.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.17 ETS75364.1 - 0.29 10.9 0.6 1.3 8.7 0.5 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein HET PF06985.11 ETS75366.1 - 0.013 15.8 0.0 0.02 15.2 0.0 1.3 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) DUF2757 PF10955.8 ETS75366.1 - 0.025 14.8 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) Asp_Glu_race PF01177.22 ETS75367.1 - 8.2e-07 29.1 0.1 1.2e-05 25.2 0.1 2.2 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase AroM PF07302.11 ETS75367.1 - 0.082 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 AroM protein NACHT PF05729.12 ETS75369.1 - 6.2e-14 52.2 0.0 2.1e-13 50.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain Ank_2 PF12796.7 ETS75369.1 - 2e-13 50.7 0.0 2.5e-05 24.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS75369.1 - 3.1e-08 34.0 0.2 0.014 16.0 0.0 3.9 4 0 0 4 4 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS75369.1 - 3.6e-08 33.1 0.1 0.056 14.0 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 ETS75369.1 - 1.8e-07 31.3 1.9 0.31 11.6 0.1 5.2 6 0 0 6 6 5 2 Ankyrin repeat Ank_5 PF13857.6 ETS75369.1 - 2.2e-06 27.8 0.8 0.075 13.4 0.0 4.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) AAA_22 PF13401.6 ETS75369.1 - 0.00011 22.5 0.0 0.00064 20.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS75369.1 - 0.00048 20.5 0.0 0.0018 18.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 ETS75369.1 - 0.028 14.0 0.0 0.07 12.7 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 ETS75369.1 - 0.037 14.0 1.7 1.5 8.9 0.4 3.0 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 ETS75369.1 - 0.04 13.2 1.3 0.87 8.8 0.2 2.4 1 1 0 2 2 2 0 KAP family P-loop domain TsaE PF02367.17 ETS75369.1 - 0.093 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Lipocalin_5 PF13924.6 ETS75370.1 - 3.3e-21 75.6 0.0 3.8e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain GMC_oxred_N PF00732.19 ETS75371.1 - 6.5e-57 193.2 0.0 8.1e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS75371.1 - 5.2e-32 111.3 0.2 1.5e-31 109.9 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.24 ETS75371.1 - 4.5e-07 29.8 3.1 2.8e-06 27.2 3.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS75371.1 - 2e-05 24.7 0.1 6e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS75371.1 - 0.00075 18.8 0.1 1 8.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS75371.1 - 0.00077 18.6 0.0 0.0046 16.1 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 ETS75371.1 - 0.025 13.8 0.2 0.062 12.5 0.2 1.6 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 ETS75371.1 - 0.055 12.5 0.4 1.5 7.8 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 ETS75371.1 - 0.13 12.2 1.2 0.5 10.3 0.0 2.2 2 1 0 2 2 2 0 FAD-NAD(P)-binding Dynamin_N PF00350.23 ETS75372.1 - 2.7e-30 105.6 0.0 5.6e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 ETS75372.1 - 2e-21 76.5 0.0 2.2e-20 73.1 0.0 2.2 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 ETS75372.1 - 0.00023 21.2 0.0 0.0019 18.3 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 ETS75372.1 - 0.072 13.3 0.0 0.39 11.0 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Profilin PF00235.19 ETS75372.1 - 0.084 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Profilin AAA_29 PF13555.6 ETS75372.1 - 0.086 12.6 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 ETS75372.1 - 0.17 11.5 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Peptidase_C97 PF05903.14 ETS75373.1 - 0.013 15.3 0.2 0.023 14.5 0.2 1.4 1 1 0 1 1 1 0 PPPDE putative peptidase domain GLEYA PF10528.9 ETS75374.1 - 4e-27 94.5 2.7 1.7e-26 92.5 0.6 2.9 2 0 0 2 2 2 1 GLEYA domain PA14 PF07691.12 ETS75374.1 - 2.4e-05 24.2 0.0 0.00016 21.5 0.0 2.4 2 0 0 2 2 2 1 PA14 domain DUF4404 PF14357.6 ETS75375.1 - 0.16 12.6 4.6 0.45 11.2 4.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Macoilin PF09726.9 ETS75375.1 - 0.95 7.9 21.4 0.13 10.8 13.9 2.0 2 0 0 2 2 2 0 Macoilin family NBD_C PF17042.5 ETS75375.1 - 1.4 9.4 6.5 1 9.8 4.7 1.8 1 1 0 1 1 1 0 Nucleotide-binding C-terminal domain MCM3AP_GANP PF16769.5 ETS75375.1 - 3.6 5.7 18.1 4.7 5.3 18.1 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP EthD PF07110.11 ETS75376.1 - 0.0014 19.7 0.1 0.14 13.4 0.1 2.1 1 1 0 1 1 1 1 EthD domain Amidohydro_1 PF01979.20 ETS75377.1 - 3.5e-24 85.8 0.0 6.1e-24 85.0 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS75377.1 - 9.8e-18 64.9 0.0 3.5e-08 33.4 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family CN_hydrolase PF00795.22 ETS75378.1 - 7.2e-42 143.5 0.0 9.5e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TPR_12 PF13424.6 ETS75383.1 - 0.25 11.6 2.1 2.3 8.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 ETS75383.1 - 0.5 10.3 2.1 13 5.8 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ETS75383.1 - 1.4 9.2 8.5 7.1 7.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MANEC PF07502.14 ETS75384.1 - 5.1e-06 26.7 7.7 0.013 15.8 0.1 2.9 2 2 0 2 2 2 2 MANEC domain PAN_4 PF14295.6 ETS75384.1 - 2.3e-05 24.2 16.6 0.00041 20.2 2.1 3.2 2 1 0 2 2 2 2 PAN domain DUF2236 PF09995.9 ETS75385.1 - 5e-51 174.1 0.7 6.3e-51 173.8 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) EDS1_EP PF18117.1 ETS75385.1 - 0.088 13.3 0.7 0.23 11.9 0.4 1.8 1 1 1 2 2 2 0 Enhanced disease susceptibility 1 protein EP domain DUF3712 PF12505.8 ETS75386.1 - 1.5e-27 96.3 1.3 1.5e-27 96.3 1.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Cyt-b5 PF00173.28 ETS75387.1 - 1.4e-19 70.0 0.4 1.9e-19 69.6 0.4 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EFP_N PF08207.12 ETS75387.1 - 0.028 14.5 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain GFO_IDH_MocA PF01408.22 ETS75388.1 - 1.3e-19 71.1 0.0 2.3e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ETS75388.1 - 0.005 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Glyco_hydro_72 PF03198.14 ETS75389.1 - 3.3e-109 365.0 4.1 5e-109 364.4 4.1 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 ETS75389.1 - 9.9e-19 67.8 6.1 3.2e-18 66.2 6.1 1.9 1 0 0 1 1 1 1 X8 domain MFS_1 PF07690.16 ETS75390.1 - 4.3e-24 85.1 40.5 4.3e-24 85.1 40.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily GGACT PF06094.12 ETS75391.1 - 3.6e-07 30.8 0.0 1e-06 29.3 0.0 1.7 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 ETS75391.1 - 1.1e-06 29.0 0.0 0.00032 21.0 0.0 2.4 2 0 0 2 2 2 2 AIG2-like family ChaC PF04752.12 ETS75391.1 - 0.1 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 ChaC-like protein Rpn3_C PF08375.11 ETS75392.1 - 1.3e-25 89.6 1.7 1.3e-25 89.6 1.7 2.4 3 0 0 3 3 3 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 ETS75392.1 - 3.8e-21 75.6 0.6 3.4e-20 72.5 0.0 2.6 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 ETS75392.1 - 0.0067 16.5 0.6 0.021 14.9 0.6 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat SWI-SNF_Ssr4 PF08549.10 ETS75392.1 - 0.46 9.1 3.9 0.86 8.2 3.9 1.4 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) TFIID_20kDa PF03847.13 ETS75394.1 - 1.1e-17 64.3 0.0 1.8e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DASH_Spc34 PF08657.10 ETS75396.1 - 4e-50 171.0 4.2 5.7e-27 95.1 0.7 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 UPF0242 PF06785.11 ETS75396.1 - 0.09 12.9 4.2 0.14 12.3 4.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 ETS75396.1 - 0.29 11.4 5.0 0.42 11.0 5.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ribosomal_60s PF00428.19 ETS75396.1 - 0.38 11.4 5.9 46 4.7 0.0 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein CRA PF06589.11 ETS75396.1 - 1.2 9.3 2.8 2.1 8.5 2.8 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DSBA PF01323.20 ETS75397.1 - 6.6e-34 117.4 0.0 7.5e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 ETS75397.1 - 0.00015 22.0 0.0 0.00028 21.1 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_5 PF13743.6 ETS75397.1 - 0.00029 20.6 0.0 0.007 16.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 ETS75397.1 - 0.019 15.0 0.0 0.073 13.1 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin domain zf-XS PF03470.14 ETS75397.1 - 0.094 13.0 0.6 4.9 7.5 0.2 2.3 2 0 0 2 2 2 0 XS zinc finger domain Polyketide_cyc2 PF10604.9 ETS75398.1 - 3.4e-07 30.6 0.3 3.8e-07 30.5 0.3 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF4520 PF15016.6 ETS75398.1 - 0.029 14.4 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) LBR_tudor PF09465.10 ETS75398.1 - 0.09 12.6 0.3 0.21 11.4 0.3 1.6 1 1 0 1 1 1 0 Lamin-B receptor of TUDOR domain Abhydrolase_3 PF07859.13 ETS75399.1 - 2.7e-44 151.5 0.3 4.6e-44 150.8 0.3 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS75399.1 - 0.00031 19.8 0.7 0.00068 18.6 0.7 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ETS75399.1 - 0.0036 16.8 0.6 0.011 15.2 0.5 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 ETS75399.1 - 0.064 12.8 0.0 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Chlorophyllase PF07224.11 ETS75399.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase Fungal_trans PF04082.18 ETS75400.1 - 1.1e-22 80.4 0.5 1.6e-22 79.8 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS75400.1 - 1.2e-06 28.5 13.0 2.3e-06 27.6 13.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 ETS75400.1 - 0.69 10.3 6.7 1.4 9.3 6.7 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Ribosomal_S2 PF00318.20 ETS75401.1 - 3.5e-63 212.7 0.0 4.1e-62 209.2 0.0 2.2 1 1 0 1 1 1 1 Ribosomal protein S2 Cpn60_TCP1 PF00118.24 ETS75402.1 - 2.7e-152 507.8 5.1 3.1e-152 507.6 5.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PNTB_4TM PF12769.7 ETS75402.1 - 0.076 13.5 0.1 0.29 11.6 0.0 2.0 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch FtsA PF14450.6 ETS75402.1 - 0.43 11.0 2.2 0.99 9.9 2.2 1.9 1 1 0 1 1 1 0 Cell division protein FtsA Nucleolin_bd PF16725.5 ETS75403.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Nucleolin binding domain PAH PF02671.21 ETS75404.1 - 2.4e-12 46.8 0.1 4.3e-12 46.0 0.1 1.4 1 0 0 1 1 1 1 Paired amphipathic helix repeat TSNAXIP1_N PF15739.5 ETS75404.1 - 0.0022 18.3 0.2 0.0029 18.0 0.2 1.2 1 0 0 1 1 1 1 Translin-associated factor X-interacting N-terminus DUF2130 PF09903.9 ETS75404.1 - 0.035 13.4 0.8 0.046 13.0 0.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) AAA_26 PF13500.6 ETS75404.1 - 0.054 13.3 0.3 0.066 13.0 0.3 1.2 1 0 0 1 1 1 0 AAA domain HAUS6_N PF14661.6 ETS75404.1 - 0.068 12.7 0.9 0.083 12.5 0.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RasGAP_C PF03836.15 ETS75404.1 - 0.076 13.2 0.6 0.098 12.8 0.6 1.1 1 0 0 1 1 1 0 RasGAP C-terminus ORC_WH_C PF18137.1 ETS75404.1 - 0.091 12.8 1.0 0.11 12.5 1.0 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF1700 PF08006.11 ETS75404.1 - 0.26 10.8 0.1 0.3 10.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Glyco_hydro_127 PF07944.12 ETS75405.1 - 7.9e-135 450.3 0.1 9.1e-135 450.1 0.1 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 MRJP PF03022.16 ETS75406.1 - 6.7e-25 88.0 0.0 9.2e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein Mito_carr PF00153.27 ETS75407.1 - 1.8e-53 178.4 4.4 1.5e-20 72.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3042 PF11240.8 ETS75407.1 - 0.28 11.2 5.0 8.5 6.5 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) XPG_N PF00752.17 ETS75408.1 - 4.4e-31 107.4 0.0 1.1e-30 106.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 ETS75408.1 - 5.3e-31 106.8 2.0 5.5e-31 106.8 0.0 2.0 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 ETS75408.1 - 1.8e-05 25.2 0.5 0.00013 22.5 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Abhydrolase_3 PF07859.13 ETS75409.1 - 1e-52 179.1 0.0 1.3e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS75409.1 - 0.00083 18.3 0.2 0.0015 17.5 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 ETS75409.1 - 0.0043 16.6 0.7 0.93 8.9 0.2 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 ETS75409.1 - 0.066 12.1 0.4 0.4 9.5 0.4 1.9 1 1 0 1 1 1 0 Steryl acetyl hydrolase Macoilin PF09726.9 ETS75410.1 - 1.1 7.7 7.4 1.3 7.4 7.4 1.0 1 0 0 1 1 1 0 Macoilin family FBPase PF00316.20 ETS75411.1 - 2.1e-24 86.1 0.7 8.8e-24 84.0 0.1 1.9 2 0 0 2 2 2 1 Fructose-1-6-bisphosphatase, N-terminal domain ADH_N PF08240.12 ETS75413.1 - 8.4e-11 41.7 0.8 5e-10 39.2 0.8 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS75413.1 - 3.2e-06 27.1 0.2 5.3e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DAGAT PF03982.13 ETS75413.1 - 0.013 14.5 0.0 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol acyltransferase ADH_N_2 PF16884.5 ETS75413.1 - 0.035 14.0 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Acyl-CoA_dh_1 PF00441.24 ETS75414.1 - 3.7e-41 140.8 0.1 5.4e-41 140.3 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ETS75414.1 - 1.3e-20 73.4 0.1 2.2e-20 72.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ETS75414.1 - 2.6e-20 73.2 0.0 5.3e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 ETS75414.1 - 7.7e-19 67.6 0.4 1.5e-18 66.7 0.4 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 ETS75414.1 - 1.3e-07 31.9 0.0 2.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain C6 PF01681.17 ETS75414.1 - 0.073 13.6 0.1 0.26 11.8 0.1 1.9 2 0 0 2 2 2 0 C6 domain Fe-S_biosyn PF01521.20 ETS75415.1 - 4.5e-12 46.1 0.0 8e-07 29.2 0.0 2.3 1 1 1 2 2 2 2 Iron-sulphur cluster biosynthesis Lgl_C PF08596.10 ETS75416.1 - 7.4e-117 390.4 0.0 1.2e-116 389.6 0.0 1.4 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 ETS75416.1 - 6.9e-08 32.7 0.0 0.012 15.9 0.0 4.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ETS75416.1 - 8.1e-07 29.7 2.0 0.011 16.6 0.1 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat PALB2_WD40 PF16756.5 ETS75416.1 - 0.034 13.1 0.0 0.071 12.0 0.0 1.4 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain AAA_12 PF13087.6 ETS75417.1 - 7.8e-40 136.6 0.0 1.5e-39 135.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ETS75417.1 - 8.9e-25 87.9 0.0 1.9e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ETS75417.1 - 1.7e-09 38.2 0.0 7e-09 36.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ETS75417.1 - 1.2e-08 34.9 0.1 3.1e-05 23.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 ETS75417.1 - 0.0018 17.6 0.1 2 7.5 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 ETS75417.1 - 0.017 14.9 0.1 0.72 9.5 0.0 3.4 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 ETS75417.1 - 0.03 14.3 0.1 0.093 12.7 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CHS5_N PF16892.5 ETS75417.1 - 0.046 13.7 0.4 0.16 12.0 0.1 2.0 2 0 0 2 2 2 0 Chitin biosynthesis protein CHS5 N-terminus GAT PF03127.14 ETS75417.1 - 0.061 13.6 0.1 0.27 11.6 0.1 2.2 1 0 0 1 1 1 0 GAT domain AAA_16 PF13191.6 ETS75417.1 - 0.098 13.0 0.4 0.73 10.2 0.1 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 ETS75417.1 - 0.13 12.5 0.1 2.8 8.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ETS75417.1 - 0.17 12.3 0.1 0.66 10.4 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DJ-1_PfpI PF01965.24 ETS75418.1 - 6.2e-18 65.1 0.0 7.4e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family CN_hydrolase PF00795.22 ETS75419.1 - 1.2e-48 165.8 0.0 1.5e-48 165.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_61 PF03443.14 ETS75420.1 - 2.4e-56 191.0 0.0 2.4e-56 191.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Gln-synt_C PF00120.24 ETS75421.1 - 1.5e-15 57.1 0.0 4.3e-11 42.4 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 ETS75421.1 - 8.4e-12 44.7 0.0 1.6e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Phosphoesterase PF04185.14 ETS75422.1 - 1.3e-21 77.2 0.6 3.7e-21 75.7 0.6 1.7 1 1 0 1 1 1 1 Phosphoesterase family Glyco_hydro_3 PF00933.21 ETS75423.1 - 7.1e-33 114.3 0.0 1.2e-32 113.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 ETS75423.1 - 2.6e-32 112.4 0.0 1.1e-31 110.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ETS75423.1 - 1.4e-05 25.1 0.0 2.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain AATase PF07247.12 ETS75424.1 - 3.6e-15 55.5 0.0 7.1e-15 54.5 0.0 1.6 1 1 0 1 1 1 1 Alcohol acetyltransferase WES_acyltransf PF03007.16 ETS75424.1 - 5.9e-05 23.0 0.2 0.00019 21.3 0.1 1.8 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain HET PF06985.11 ETS75425.1 - 9.9e-35 120.0 0.2 1.7e-34 119.3 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 ETS75425.1 - 1.4e-21 76.9 4.7 1.4e-05 25.6 0.0 6.5 4 2 2 7 7 7 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS75425.1 - 1.1e-15 56.1 8.8 0.93 10.3 0.0 10.0 10 0 0 10 10 10 4 Ankyrin repeat Ank_4 PF13637.6 ETS75425.1 - 3.1e-13 49.9 3.5 0.00014 22.3 0.0 6.7 3 2 4 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 ETS75425.1 - 3.8e-11 42.9 11.4 0.0015 18.9 0.0 7.7 7 1 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 ETS75425.1 - 6.4e-10 39.1 0.8 0.0091 16.3 0.0 4.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) DUF2399 PF09664.10 ETS75425.1 - 0.028 14.3 0.0 0.18 11.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2399) DUF1835 PF08874.10 ETS75425.1 - 0.031 14.5 0.5 0.086 13.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1835) MFS_1 PF07690.16 ETS75426.1 - 1.7e-29 102.8 22.4 1.7e-29 102.8 22.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS75426.1 - 1e-08 34.9 4.6 2.3e-08 33.7 4.6 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Trp_oprn_chp PF09534.10 ETS75426.1 - 0.016 15.0 0.4 0.47 10.2 0.0 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TMEM100 PF16311.5 ETS75426.1 - 1.2 8.7 3.5 2.9 7.5 0.3 2.9 3 1 1 4 4 4 0 Transmembrane protein 100 CoA_transf_3 PF02515.17 ETS75428.1 - 1.3e-42 146.3 0.0 1.8e-39 135.9 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III adh_short_C2 PF13561.6 ETS75429.1 - 2e-55 187.9 1.9 2.3e-55 187.7 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS75429.1 - 6.8e-47 159.5 1.8 8.4e-47 159.2 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Abhydrolase_3 PF07859.13 ETS75430.1 - 6.6e-49 166.6 0.0 8.9e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS75430.1 - 1.6e-10 40.5 1.7 7.9e-10 38.2 1.7 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 ETS75430.1 - 6.5e-05 23.6 0.5 9.5e-05 23.1 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ETS75430.1 - 0.13 11.7 0.0 6.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ETS75432.1 - 6.2e-18 65.4 0.0 1.3e-17 64.3 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS75432.1 - 2e-11 44.9 0.5 2.9e-11 44.4 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS75432.1 - 7.6e-06 25.4 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FMO-like PF00743.19 ETS75433.1 - 8.9e-14 50.8 0.1 4.5e-12 45.2 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ETS75433.1 - 1.1e-10 41.2 0.3 4.6e-08 32.6 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ETS75433.1 - 1.9e-09 37.2 0.0 5.2e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS75433.1 - 1.1e-08 34.8 0.0 1.9e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS75433.1 - 1.8e-07 31.3 0.0 1.2e-05 25.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 ETS75433.1 - 0.00041 20.4 0.2 0.0065 16.5 0.0 2.5 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 ETS75433.1 - 0.0017 18.8 1.5 1.3 9.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS75433.1 - 0.0021 17.3 2.3 0.064 12.5 0.2 2.7 3 0 0 3 3 3 1 Thi4 family IlvN PF07991.12 ETS75433.1 - 0.0036 16.9 0.5 0.12 11.9 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 ETS75433.1 - 0.0039 17.6 0.0 0.48 10.9 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.6 ETS75433.1 - 0.016 15.2 0.0 2.1 8.3 0.0 2.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 ETS75433.1 - 0.038 13.3 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ETS75433.1 - 0.051 13.7 0.1 0.12 12.5 0.0 1.7 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.24 ETS75433.1 - 0.056 13.0 0.2 12 5.4 0.0 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase Tudor_4 PF18358.1 ETS75433.1 - 0.11 12.1 0.1 0.26 10.9 0.1 1.6 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain ThiF PF00899.21 ETS75433.1 - 0.22 10.8 0.4 0.63 9.3 0.0 1.9 2 0 0 2 2 2 0 ThiF family 3HCDH_N PF02737.18 ETS75433.1 - 0.33 10.8 1.2 3 7.7 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WSC PF01822.19 ETS75434.1 - 1.1e-68 227.5 74.8 1e-18 67.3 15.7 4.1 4 0 0 4 4 4 4 WSC domain Acetyltransf_1 PF00583.25 ETS75436.1 - 0.05 13.9 0.1 0.087 13.1 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family p450 PF00067.22 ETS75437.1 - 7.5e-60 203.0 0.0 9.2e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAM221 PF14753.6 ETS75440.1 - 0.078 12.5 5.7 0.088 12.4 5.7 1.0 1 0 0 1 1 1 0 Protein FAM221A/B Fungal_trans PF04082.18 ETS75441.1 - 3.2e-34 118.2 0.0 1e-33 116.5 0.0 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS75441.1 - 4.3e-09 36.3 8.1 9.9e-09 35.2 8.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CN_hydrolase PF00795.22 ETS75442.1 - 6.4e-44 150.2 0.0 8.5e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asp PF00026.23 ETS75443.1 - 8.5e-111 370.4 0.1 1e-110 370.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS75443.1 - 6.5e-17 62.3 1.8 3.5e-15 56.7 0.8 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ETS75443.1 - 2.1e-06 28.3 0.2 0.036 14.7 0.0 3.5 2 2 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ETS75443.1 - 0.00013 22.4 0.0 0.24 12.0 0.0 2.8 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 ETS75443.1 - 0.0012 18.7 0.0 0.028 14.2 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal BDHCT_assoc PF16204.5 ETS75443.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein FAD_binding_2 PF00890.24 ETS75444.1 - 5.1e-61 207.0 4.1 6e-61 206.8 4.1 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS75444.1 - 6.1e-11 42.5 3.8 3.1e-10 40.2 3.8 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS75444.1 - 2.5e-08 34.0 0.8 1.1e-07 32.0 0.8 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ETS75444.1 - 2.9e-07 30.2 1.9 8.4e-07 28.7 1.9 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ETS75444.1 - 1.7e-05 24.3 1.6 7.5e-05 22.1 1.6 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS75444.1 - 4.7e-05 22.8 0.5 0.00011 21.6 0.5 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS75444.1 - 5.3e-05 22.5 3.2 0.0001 21.6 1.3 2.3 2 1 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 ETS75444.1 - 0.00017 20.4 0.4 0.00045 19.1 0.4 1.7 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 ETS75444.1 - 0.00034 20.0 0.2 0.00091 18.6 0.2 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 ETS75444.1 - 0.0019 18.7 0.2 0.035 14.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS75444.1 - 0.0034 16.7 0.6 0.018 14.3 0.3 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 ETS75444.1 - 0.0048 16.2 0.0 0.11 11.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 ETS75444.1 - 0.1 12.5 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 ETS75444.1 - 0.13 11.3 0.2 0.23 10.4 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.16 ETS75445.1 - 8e-33 113.8 29.2 2.3e-31 109.0 26.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4381 PF14316.6 ETS75445.1 - 4.5 7.5 4.8 12 6.1 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Lipase_GDSL_2 PF13472.6 ETS75446.1 - 4.3e-15 56.6 0.1 5.4e-15 56.2 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS75446.1 - 1.6e-05 25.0 0.0 3e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 ETS75446.1 - 0.043 13.9 0.1 0.25 11.4 0.0 2.0 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family PALP PF00291.25 ETS75447.1 - 2.5e-53 181.4 0.0 3.1e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SHMT PF00464.19 ETS75448.1 - 6.6e-208 690.1 0.0 7.7e-208 689.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.19 ETS75448.1 - 0.0029 16.6 0.0 0.0044 16.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ETS75448.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 ETS75448.1 - 0.14 10.7 0.0 0.25 9.8 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme FR47 PF08445.10 ETS75448.1 - 0.21 11.5 0.2 1.7 8.7 0.0 2.5 3 0 0 3 3 3 0 FR47-like protein GST_N_3 PF13417.6 ETS75449.1 - 4.9e-07 30.1 0.0 9.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ETS75449.1 - 0.00011 22.4 0.1 0.00062 20.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS75449.1 - 0.00097 19.1 1.2 0.0023 17.9 1.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ETS75449.1 - 0.0078 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ETS75449.1 - 0.028 14.7 0.0 0.037 14.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ETS75449.1 - 0.069 13.9 0.0 0.16 12.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Alpha_L_fucos PF01120.17 ETS75451.1 - 6.5e-86 288.9 7.4 8.8e-86 288.5 7.4 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.6 ETS75451.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Glyco_hydro_43 PF04616.14 ETS75452.1 - 2.3e-66 224.1 2.5 2.9e-66 223.7 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ETS75452.1 - 3.3e-17 62.9 0.0 5.4e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Bromodomain PF00439.25 ETS75453.1 - 9.8e-21 73.6 0.4 2.2e-20 72.5 0.4 1.6 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 ETS75453.1 - 3e-10 40.0 0.0 1.1e-09 38.1 0.0 2.0 1 1 0 1 1 1 1 Bromodomain associated SPARC_Ca_bdg PF10591.9 ETS75453.1 - 0.83 10.0 4.4 1.5 9.2 3.2 2.1 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region VanZ PF04892.12 ETS75454.1 - 5e-06 27.2 3.1 6.8e-06 26.7 3.1 1.2 1 0 0 1 1 1 1 VanZ like family DUF2162 PF09930.9 ETS75454.1 - 0.036 13.5 4.8 0.048 13.1 4.8 1.1 1 0 0 1 1 1 0 Predicted transporter (DUF2162) Pyridoxal_deC PF00282.19 ETS75455.1 - 7e-73 245.5 0.0 8.7e-73 245.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 ETS75455.1 - 2e-06 27.3 0.0 2.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 ETS75455.1 - 0.0007 18.6 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V SepSecS PF05889.13 ETS75455.1 - 0.0024 16.6 0.0 0.0036 16.0 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Glyco_transf_20 PF00982.21 ETS75455.1 - 0.23 10.1 0.0 0.33 9.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 20 adh_short PF00106.25 ETS75456.1 - 2.3e-34 118.6 0.0 5.3e-34 117.4 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS75456.1 - 1e-18 67.8 0.0 1.8e-18 67.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS75456.1 - 1.6e-13 50.9 0.1 2.3e-13 50.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS75456.1 - 4.1e-06 26.4 0.0 5.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS75456.1 - 7.4e-06 25.6 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 ETS75456.1 - 1e-05 25.8 0.2 6.4e-05 23.2 0.2 2.0 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 ETS75456.1 - 0.00094 18.4 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ETS75456.1 - 0.0014 17.9 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Abhydrolase_3 PF07859.13 ETS75457.1 - 4.9e-53 180.1 0.1 6e-53 179.8 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS75457.1 - 4.5e-05 22.5 0.0 6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ETS75457.1 - 0.00016 21.2 0.0 0.056 12.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 ETS75457.1 - 0.0042 16.7 0.0 0.0073 15.9 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family PUF PF00806.19 ETS75459.1 - 1.6e-11 43.2 1.6 1.2 8.9 0.0 6.9 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat M20_dimer PF07687.14 ETS75460.1 - 2.1e-21 75.9 0.0 3.4e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 ETS75460.1 - 6.9e-19 68.4 2.8 7.4e-18 65.0 2.8 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 ETS75460.1 - 0.0023 17.7 0.6 0.0035 17.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Glyco_hyd_65N_2 PF14498.6 ETS75462.1 - 2.1e-51 175.1 0.1 2.8e-51 174.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Ank_2 PF12796.7 ETS75464.1 - 2.2e-30 105.1 2.3 7e-06 26.5 0.1 5.8 5 2 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS75464.1 - 1.3e-25 89.1 4.5 2.2e-09 37.4 0.3 5.9 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS75464.1 - 9.9e-25 86.6 11.8 4.4e-06 27.1 0.7 7.5 5 4 4 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 ETS75464.1 - 4e-22 77.6 13.4 0.0017 18.7 0.8 8.0 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 ETS75464.1 - 2.3e-20 70.5 15.2 0.0011 19.3 0.0 8.3 10 0 0 10 10 10 4 Ankyrin repeat Trp_DMAT PF11991.8 ETS75465.1 - 5.2e-80 269.6 0.0 6.5e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase adh_short PF00106.25 ETS75466.1 - 2.9e-19 69.3 0.0 4.1e-14 52.5 0.0 2.4 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS75466.1 - 4.5e-06 26.4 0.0 0.00023 20.8 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS75466.1 - 1e-05 25.5 0.1 1.5e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS75466.1 - 0.034 13.3 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Lactamase_B PF00753.27 ETS75468.1 - 8.8e-22 78.1 0.3 1.2e-21 77.7 0.3 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS75468.1 - 1.5e-08 34.4 0.1 2.3e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Fungal_trans PF04082.18 ETS75469.1 - 1.6e-27 96.2 0.1 2.3e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tyrosinase PF00264.20 ETS75470.1 - 1.2e-33 117.3 2.2 2.3e-33 116.3 2.2 1.4 1 1 0 1 1 1 1 Common central domain of tyrosinase LRR_11 PF18831.1 ETS75470.1 - 0.3 10.7 0.9 3.4 7.3 0.5 2.3 2 0 0 2 2 2 0 Leucine-rich repeat Tyrosinase PF00264.20 ETS75471.1 - 1.8e-28 100.3 7.0 4.9e-28 98.9 7.0 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase Fungal_lectin PF07938.12 ETS75474.1 - 8.1e-09 35.3 2.1 2.4e-06 27.1 0.0 2.7 2 1 1 3 3 3 2 Fungal fucose-specific lectin Rick_17kDa_Anti PF05433.15 ETS75474.1 - 0.012 15.4 1.9 0.03 14.2 1.9 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain SecE PF00584.20 ETS75474.1 - 0.097 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex adh_short PF00106.25 ETS75475.1 - 4.2e-38 130.8 0.0 5.1e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS75475.1 - 3.4e-28 98.8 0.0 4.5e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS75475.1 - 1.4e-09 38.1 0.0 2.2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ETS75475.1 - 0.00042 20.2 0.0 0.00066 19.6 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding SesA PF17107.5 ETS75476.1 - 0.00019 21.6 0.3 0.00059 20.0 0.1 1.8 1 1 1 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases CSN5_C PF18323.1 ETS75476.1 - 0.0063 17.4 0.8 2.1 9.3 0.2 2.2 2 0 0 2 2 2 2 Cop9 signalosome subunit 5 C-terminal domain Sugar_tr PF00083.24 ETS75477.1 - 5.7e-84 282.6 24.9 7e-84 282.3 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS75477.1 - 1.5e-36 126.1 38.0 1.7e-29 102.9 17.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.7 ETS75477.1 - 0.22 11.7 19.0 2.1 8.5 3.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) SLT_beta PF02258.16 ETS75477.1 - 0.33 11.0 2.3 0.75 9.9 0.5 2.3 1 1 1 2 2 2 0 Shiga-like toxin beta subunit PhyH PF05721.13 ETS75478.1 - 2.1e-08 34.7 0.1 3.6e-08 33.9 0.1 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 ETS75478.1 - 6.8e-06 25.1 0.1 0.035 12.9 0.0 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) Fungal_trans_2 PF11951.8 ETS75479.1 - 1.5e-45 155.7 1.8 2.2e-45 155.1 1.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.7 ETS75480.1 - 2.6e-45 152.9 1.1 6e-11 42.8 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS75480.1 - 8.8e-36 121.5 2.7 5.7e-08 32.9 0.2 6.6 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 ETS75480.1 - 2.6e-33 113.0 3.9 0.0013 19.1 0.0 9.4 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 ETS75480.1 - 9.5e-33 112.2 2.7 3e-06 27.6 0.0 8.0 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS75480.1 - 2.8e-28 94.8 0.6 0.0044 17.4 0.0 10.3 10 0 0 10 10 10 7 Ankyrin repeat GATase_7 PF13537.6 ETS75480.1 - 0.0027 17.6 0.0 17 5.3 0.0 4.6 3 1 2 5 5 5 1 Glutamine amidotransferase domain CHAT PF12770.7 ETS75481.1 - 1.1e-34 120.2 0.0 1.5e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 CHAT domain Peptidase_C25 PF01364.18 ETS75481.1 - 0.0063 15.8 0.0 0.0097 15.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C25 Peptidase_C50 PF03568.17 ETS75481.1 - 0.0095 15.1 0.0 0.034 13.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase family C50 Peptidase_C14 PF00656.22 ETS75481.1 - 0.064 13.2 0.0 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Caspase domain MFS_1 PF07690.16 ETS75482.1 - 3.7e-32 111.6 41.0 3.7e-32 111.6 41.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Amidase PF01425.21 ETS75483.1 - 5.2e-114 381.7 0.0 7.1e-114 381.2 0.0 1.2 1 0 0 1 1 1 1 Amidase p450 PF00067.22 ETS75484.1 - 4.9e-53 180.5 0.0 7.3e-31 107.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 ketoacyl-synt PF00109.26 ETS75485.1 - 2.4e-64 217.3 0.0 4.5e-64 216.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 ETS75485.1 - 1.6e-52 178.6 0.0 2.6e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ETS75485.1 - 4.2e-51 174.4 0.0 7.1e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 ETS75485.1 - 5.4e-51 173.0 0.5 5.4e-51 173.0 0.5 2.2 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 ETS75485.1 - 1.4e-32 112.1 3.9 3.8e-32 110.8 0.4 2.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ETS75485.1 - 2.2e-20 73.2 0.0 5.5e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 ETS75485.1 - 1.6e-18 68.0 0.0 1.2e-17 65.2 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ETS75485.1 - 2.4e-17 63.1 0.9 6.3e-17 61.8 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 ETS75485.1 - 1.4e-12 47.5 2.4 7.9e-10 38.5 0.3 3.4 3 0 0 3 3 3 2 short chain dehydrogenase PP-binding PF00550.25 ETS75485.1 - 6.6e-07 29.6 0.0 1.6e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 ETS75485.1 - 5.6e-06 26.1 2.1 0.00011 21.9 0.3 3.2 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase SAT PF16073.5 ETS75485.1 - 5.9e-05 22.9 0.1 0.0024 17.6 0.1 2.4 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Peptidase_S15 PF02129.18 ETS75486.1 - 2.1e-07 30.8 0.0 7.6e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 ETS75486.1 - 3.7e-07 29.7 0.0 7.6e-07 28.6 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ETS75486.1 - 5.1e-07 29.4 0.0 0.00011 21.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ETS75486.1 - 1.1e-06 28.4 0.0 2.8e-06 27.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS75486.1 - 2e-06 28.6 0.1 2.6e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 ETS75486.1 - 5.6e-06 25.3 0.0 8.6e-06 24.6 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 ETS75486.1 - 2.5e-05 24.3 0.0 9.9e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 ETS75486.1 - 0.025 14.1 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family p450 PF00067.22 ETS75487.1 - 1.7e-42 145.8 0.0 2.2e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4131 PF13567.6 ETS75487.1 - 0.059 13.0 0.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) 2OG-FeII_Oxy PF03171.20 ETS75488.1 - 2.9e-13 50.2 0.0 6.1e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ETS75488.1 - 1.5e-07 32.2 0.0 2.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Asn_synthase PF00733.21 ETS75489.1 - 6e-68 230.1 0.3 8.4e-68 229.6 0.3 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 ETS75489.1 - 9.6e-36 122.4 0.0 1.7e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ETS75489.1 - 1.6e-33 115.7 0.0 2.9e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 ETS75489.1 - 0.0018 17.8 0.0 0.0043 16.5 0.0 1.6 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 ETS75489.1 - 0.04 13.0 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Zn_clus PF00172.18 ETS75490.1 - 3e-05 24.0 8.6 5.2e-05 23.3 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain T4BSS_DotH_IcmK PF12293.8 ETS75490.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative outer membrane core complex of type IVb secretion UPF0506 PF11703.8 ETS75490.1 - 1.6 9.2 6.7 15 6.1 6.7 2.1 1 1 0 1 1 1 0 UPF0506 PDCD2_C PF04194.13 ETS75491.1 - 1.6e-43 148.8 0.1 2.3e-42 145.0 0.0 2.6 3 1 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Ndc1_Nup PF09531.10 ETS75491.1 - 0.064 11.9 2.0 0.07 11.8 2.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Choline_transpo PF04515.12 ETS75492.1 - 1.6e-82 277.4 24.8 1.6e-82 277.4 24.8 2.5 2 1 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.13 ETS75492.1 - 0.055 14.1 2.1 0.13 12.9 2.1 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5134 PF17197.4 ETS75492.1 - 2 8.3 7.2 3.9 7.4 0.4 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5134) Pho88 PF10032.9 ETS75493.1 - 0.2 10.9 0.0 0.54 9.5 0.0 1.7 1 0 0 1 1 1 0 Phosphate transport (Pho88) Esterase_phd PF10503.9 ETS75495.1 - 3.5e-22 79.0 1.4 4.5e-22 78.6 1.4 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ETS75495.1 - 2.1e-13 50.2 1.0 3e-13 49.8 1.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ETS75495.1 - 0.0047 16.8 0.2 0.011 15.6 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS75495.1 - 0.072 11.9 0.3 0.1 11.4 0.3 1.2 1 0 0 1 1 1 0 Carboxylesterase family MFS_1 PF07690.16 ETS75496.1 - 1.9e-15 56.6 25.0 1.9e-15 56.6 25.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 ETS75496.1 - 0.00041 18.8 3.1 0.013 13.9 3.1 2.3 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Galanin PF01296.18 ETS75496.1 - 0.12 12.4 0.1 0.32 11.0 0.1 1.8 1 0 0 1 1 1 0 Galanin Sec23_helical PF04815.15 ETS75496.1 - 0.12 12.2 0.4 0.82 9.5 0.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 helical domain RPE65 PF03055.15 ETS75497.1 - 1.4e-106 357.5 0.0 1.6e-106 357.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein CFEM PF05730.11 ETS75498.1 - 0.00048 20.2 5.8 0.00065 19.7 5.8 1.2 1 0 0 1 1 1 1 CFEM domain Acetyltransf_14 PF03421.16 ETS75498.1 - 0.068 13.2 0.0 0.089 12.9 0.0 1.1 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase COesterase PF00135.28 ETS75499.1 - 3.2e-90 303.4 1.4 4e-77 260.2 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS75499.1 - 0.00092 19.1 0.1 0.0022 17.9 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_GDSL PF00657.22 ETS75500.1 - 7.7e-10 39.1 0.4 1.2e-09 38.5 0.4 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Aminotran_3 PF00202.21 ETS75501.1 - 3.1e-92 309.3 0.0 3.8e-92 309.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ETS75501.1 - 7e-06 25.4 0.0 0.00026 20.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II PAS_4 PF08448.10 ETS75502.1 - 0.082 13.2 0.0 1 9.6 0.0 2.4 2 0 0 2 2 2 0 PAS fold Zn_clus PF00172.18 ETS75503.1 - 2.6e-07 30.6 12.1 4.2e-07 30.0 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YEATS PF03366.16 ETS75504.1 - 4e-22 78.0 0.3 8.8e-22 76.9 0.2 1.6 2 0 0 2 2 2 1 YEATS family BET PF17035.5 ETS75504.1 - 0.0015 18.7 0.3 0.0015 18.7 0.3 2.2 4 0 0 4 4 4 1 Bromodomain extra-terminal - transcription regulation Dynamin_N PF00350.23 ETS75505.1 - 1.9e-16 60.6 0.0 4.4e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 ETS75505.1 - 5.3e-10 39.4 0.0 2.5e-09 37.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ETS75505.1 - 1.3e-06 28.2 0.4 2.1e-05 24.2 0.4 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 ETS75505.1 - 0.015 14.4 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) cobW PF02492.19 ETS75505.1 - 0.023 14.3 0.8 0.49 9.9 0.7 2.8 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 ETS75505.1 - 0.042 14.4 0.0 0.17 12.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain PMEI PF04043.15 ETS75505.1 - 0.043 14.2 0.1 0.12 12.7 0.1 1.8 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor DegS PF05384.11 ETS75505.1 - 0.051 13.1 0.2 0.16 11.5 0.2 1.9 1 0 0 1 1 1 0 Sensor protein DegS TsaE PF02367.17 ETS75505.1 - 0.057 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 ETS75505.1 - 0.079 12.7 0.0 0.28 10.9 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2408 PF10303.9 ETS75505.1 - 0.29 11.7 3.1 0.76 10.3 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) Snf7 PF03357.21 ETS75506.1 - 1.4e-33 115.9 21.8 1.4e-33 115.9 21.8 1.4 2 0 0 2 2 2 1 Snf7 Peptidase_M66 PF10462.9 ETS75506.1 - 0.016 14.1 0.4 0.024 13.6 0.4 1.4 1 0 0 1 1 1 0 Peptidase M66 CaMBD PF02888.16 ETS75506.1 - 0.029 14.5 0.8 0.029 14.5 0.8 2.4 3 0 0 3 3 3 0 Calmodulin binding domain Ist1 PF03398.14 ETS75506.1 - 0.031 14.2 7.3 0.056 13.4 7.3 1.5 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway RHH_8 PF17723.1 ETS75506.1 - 0.04 14.1 3.8 0.22 11.7 0.1 2.4 1 1 1 2 2 2 0 Ribbon-Helix-Helix transcriptional regulator family Hpt PF01627.23 ETS75506.1 - 0.21 11.9 2.9 0.7 10.2 2.8 2.1 1 1 0 1 1 1 0 Hpt domain HSCB_C PF07743.13 ETS75506.1 - 2.8 8.5 12.5 0.22 12.0 2.7 2.8 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Peptidase_S46 PF10459.9 ETS75506.1 - 7.5 5.1 11.6 17 3.9 11.6 1.5 1 1 0 1 1 1 0 Peptidase S46 Fe-ADH PF00465.19 ETS75507.1 - 2.1e-63 214.4 0.0 2.5e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ETS75507.1 - 6.2e-09 35.9 0.3 9.8e-05 22.2 0.1 2.4 2 1 0 2 2 2 2 Iron-containing alcohol dehydrogenase PP2C PF00481.21 ETS75508.1 - 2.5e-61 207.5 0.5 1e-50 172.8 0.1 3.3 2 1 1 3 3 3 2 Protein phosphatase 2C Cofilin_ADF PF00241.20 ETS75509.1 - 0.015 15.1 0.0 0.043 13.6 0.0 1.8 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein IFP_35_N PF07334.13 ETS75509.1 - 0.028 14.5 0.3 2.9 8.0 0.0 3.3 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Methyltransf_23 PF13489.6 ETS75510.1 - 1.6e-15 57.3 0.0 2.6e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS75510.1 - 3.5e-07 30.9 0.0 1.1e-06 29.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS75510.1 - 1.9e-06 28.5 0.0 0.0001 22.9 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS75510.1 - 2.8e-05 24.7 0.0 0.00031 21.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS75510.1 - 0.00022 21.0 0.0 0.07 12.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_4 PF02390.17 ETS75510.1 - 0.013 15.0 0.0 0.042 13.3 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 ETS75510.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 ETS75510.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_23 PF13489.6 ETS75511.1 - 3.7e-19 69.1 0.0 5.7e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS75511.1 - 2e-09 38.1 0.0 4.5e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS75511.1 - 3.3e-08 34.1 0.0 4.7e-07 30.4 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS75511.1 - 1.5e-06 28.8 0.0 9.7e-06 26.2 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS75511.1 - 1.5e-06 28.1 0.0 0.07 12.9 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain SH3_1 PF00018.28 ETS75512.1 - 2.1e-05 24.0 0.6 6.9e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 SH3 domain gpW PF02831.15 ETS75512.1 - 0.028 14.3 0.0 0.12 12.3 0.0 2.1 1 0 0 1 1 1 0 gpW SH3_9 PF14604.6 ETS75512.1 - 0.038 13.8 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain FAD_binding_7 PF03441.14 ETS75513.1 - 1.8e-72 243.0 0.1 2.8e-72 242.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ETS75513.1 - 3e-37 128.2 0.0 1.1e-36 126.3 0.0 1.9 2 0 0 2 2 2 1 DNA photolyase DUF543 PF04418.12 ETS75516.1 - 2.8e-30 104.1 0.0 3.3e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.9 ETS75517.1 - 4.5e-59 199.8 0.2 1.3e-58 198.3 0.2 1.9 1 0 0 1 1 1 1 Urb2/Npa2 family TIM PF00121.18 ETS75520.1 - 1.5e-92 309.4 1.2 1.7e-92 309.2 1.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF4169 PF13770.6 ETS75520.1 - 0.15 12.4 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4169) L51_S25_CI-B8 PF05047.16 ETS75521.1 - 4.2e-15 55.4 0.0 6.1e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Pro_CA PF00484.19 ETS75521.1 - 0.018 15.3 0.0 0.022 15.0 0.0 1.1 1 0 0 1 1 1 0 Carbonic anhydrase U1snRNP70_N PF12220.8 ETS75522.1 - 2.4e-24 85.8 2.7 4.3e-24 85.0 2.7 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 ETS75522.1 - 1.1e-16 60.4 0.1 5.1e-16 58.3 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ETS75522.1 - 2.1e-05 24.5 0.0 3.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif Ribosomal_L10 PF00466.20 ETS75523.1 - 6.6e-23 80.7 0.0 9.3e-23 80.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 ETS75523.1 - 1.5e-20 72.9 0.0 2.8e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P zf-Tim10_DDP PF02953.15 ETS75524.1 - 1.7e-16 59.6 4.6 2.1e-16 59.3 4.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Nup188_C PF18378.1 ETS75525.1 - 9.6e-157 521.5 0.4 1.6e-156 520.8 0.4 1.4 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 ETS75525.1 - 2.7e-54 184.5 1.8 1.6e-44 152.1 0.2 3.0 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.21 ETS75526.1 - 9.9e-95 316.5 0.2 1.5e-94 315.9 0.2 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 ETS75526.1 - 7.7e-47 159.5 0.0 6.4e-46 156.5 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I PRAI PF00697.22 ETS75526.1 - 4.5e-45 153.8 0.0 1.2e-41 142.7 0.0 2.6 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 ETS75526.1 - 0.0004 20.2 0.3 0.002 17.9 0.4 2.0 1 1 0 1 1 1 1 Peptidase C26 FMN_dh PF01070.18 ETS75526.1 - 0.0034 16.5 0.2 0.032 13.3 0.1 2.1 1 1 1 2 2 2 1 FMN-dependent dehydrogenase NanE PF04131.14 ETS75526.1 - 0.0088 15.2 0.9 1.4 8.0 0.0 4.0 4 1 1 5 5 5 1 Putative N-acetylmannosamine-6-phosphate epimerase GGA_N-GAT PF18308.1 ETS75526.1 - 0.037 13.6 0.1 0.079 12.6 0.1 1.5 1 0 0 1 1 1 0 GGA N-GAT domain QRPTase_C PF01729.19 ETS75526.1 - 0.19 11.5 1.9 1.1 9.0 0.1 2.6 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain MFS_1 PF07690.16 ETS75527.1 - 6.6e-22 77.9 54.7 2.8e-21 75.9 54.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily SAM_2 PF07647.17 ETS75528.1 - 4.9e-15 55.4 0.0 1.1e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ETS75528.1 - 6.5e-14 52.1 0.0 1.2e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 ETS75528.1 - 5.3e-12 46.2 0.0 1.1e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 ETS75528.1 - 0.049 13.6 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Helo_like_N PF17111.5 ETS75529.1 - 7.1e-05 22.3 0.1 9.9e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 ETS75529.1 - 0.00075 19.7 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Rx_N PF18052.1 ETS75529.1 - 0.016 15.5 0.1 0.036 14.3 0.1 1.6 1 0 0 1 1 1 0 Rx N-terminal domain Asp PF00026.23 ETS75531.1 - 8.9e-14 51.6 0.0 1.6e-13 50.8 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF2967 PF11179.8 ETS75531.1 - 0.24 9.5 0.0 0.33 9.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Ras PF00071.22 ETS75532.1 - 3.7e-15 55.9 0.0 4.6e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1_Xtn PF16897.5 ETS75532.1 - 0.25 11.4 0.0 0.34 11.0 0.0 1.1 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF1295 PF06966.12 ETS75533.1 - 3.9e-30 105.1 0.1 5.5e-30 104.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 ETS75533.1 - 0.00017 21.9 0.0 0.00034 21.0 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 ETS75533.1 - 0.0026 18.1 0.0 0.0054 17.1 0.0 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 ETS75533.1 - 0.0029 16.4 0.0 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 ETS75533.1 - 0.019 14.9 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase AidB_N PF18158.1 ETS75533.1 - 0.057 13.3 0.8 3 7.7 0.1 2.9 2 1 0 3 3 3 0 Adaptive response protein AidB N-terminal domain DUF2465 PF10239.9 ETS75534.1 - 0.019 14.2 0.0 0.027 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) MARVEL PF01284.23 ETS75534.1 - 4.4 7.3 13.1 24 5.0 13.2 2.0 1 1 0 1 1 1 0 Membrane-associating domain Glyco_hydro_15 PF00723.21 ETS75535.1 - 7.2e-92 308.5 0.5 8.3e-92 308.3 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Pectate_lyase PF03211.13 ETS75536.1 - 2.1e-86 288.7 5.2 2.1e-86 288.7 5.2 1.7 2 0 0 2 2 2 1 Pectate lyase PPP4R2 PF09184.11 ETS75536.1 - 0.2 11.2 17.7 0.29 10.7 17.7 1.2 1 0 0 1 1 1 0 PPP4R2 SAPS PF04499.15 ETS75536.1 - 0.75 8.5 7.8 0.88 8.3 7.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RXT2_N PF08595.11 ETS75536.1 - 0.79 9.7 6.6 1.4 8.9 6.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 ETS75536.1 - 5.3 5.2 11.7 7.4 4.7 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein UPF0560 PF10577.9 ETS75536.1 - 6.4 5.1 16.7 8.4 4.7 16.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Coilin_N PF15862.5 ETS75536.1 - 7.6 6.3 12.5 17 5.2 12.5 1.6 1 1 0 1 1 1 0 Coilin N-terminus MFS_1 PF07690.16 ETS75537.1 - 5.6e-46 157.1 38.0 5.6e-46 157.1 38.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS75537.1 - 3.5e-10 39.3 4.2 3.5e-10 39.3 4.2 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 ETS75537.1 - 0.00073 18.1 1.1 0.0011 17.5 1.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 ETS75537.1 - 0.0031 16.4 2.2 0.0031 16.4 2.2 2.0 1 1 0 1 1 1 1 POT family TssO PF17561.2 ETS75537.1 - 0.22 11.6 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Type VI secretion system, TssO Corona_S2 PF01601.16 ETS75537.1 - 2.2 6.7 3.4 4.5 5.6 3.4 1.4 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein FAD_binding_3 PF01494.19 ETS75538.1 - 2.8e-18 66.3 0.5 4.6e-18 65.6 0.5 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS75538.1 - 1e-10 41.7 1.3 0.00018 21.2 0.1 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS75538.1 - 1.7e-05 24.3 0.1 0.00065 19.0 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS75538.1 - 0.00012 22.6 0.0 0.00032 21.2 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ETS75538.1 - 0.00037 20.1 0.0 0.0014 18.3 0.1 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 ETS75538.1 - 0.0011 19.1 0.1 0.0032 17.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS75538.1 - 0.0066 15.6 0.2 0.016 14.3 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 ETS75538.1 - 0.02 13.8 0.3 0.55 9.0 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 ETS75538.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.23 ETS75538.1 - 0.21 11.5 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ank_2 PF12796.7 ETS75539.1 - 7.2e-22 77.8 1.7 1.7e-06 28.5 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS75539.1 - 9.9e-14 51.2 1.0 0.0032 17.7 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS75539.1 - 3.9e-12 46.4 1.3 2e-05 25.0 0.1 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS75539.1 - 5.4e-08 32.5 2.5 0.73 10.6 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 ETS75539.1 - 4.3e-06 26.9 6.4 2 9.0 0.3 5.4 4 1 0 4 4 4 2 Ankyrin repeat Fungal_trans PF04082.18 ETS75541.1 - 4.8e-12 45.5 0.3 8e-12 44.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS75541.1 - 7.3e-09 35.6 10.5 1.3e-08 34.8 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_24 PF18404.1 ETS75544.1 - 6.7e-149 494.6 2.6 1.3e-148 493.6 2.6 1.5 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 ETS75544.1 - 2.2e-74 250.6 0.0 5e-73 246.2 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 ETS75544.1 - 9.9e-56 189.0 0.0 4e-54 183.8 0.2 2.6 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 ETS75544.1 - 4.3e-50 170.3 0.2 5e-49 166.8 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 ETS75544.1 - 5.9e-44 149.3 0.2 7.3e-43 145.7 0.0 2.9 4 0 0 4 4 4 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 ETS75544.1 - 4.5e-42 142.6 0.0 9.1e-42 141.6 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 ETS75544.1 - 1e-05 25.3 0.9 2.4e-05 24.0 0.4 1.9 2 1 0 2 2 2 1 Glycosyl transferase family 8 DUF3945 PF13101.6 ETS75544.1 - 0.17 11.6 0.3 0.4 10.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) Coatomer_WDAD PF04053.14 ETS75545.1 - 3e-147 491.3 0.0 5.3e-147 490.5 0.0 1.4 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 ETS75545.1 - 1.3e-92 310.7 0.0 1.8e-92 310.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 ETS75545.1 - 2.1e-38 129.6 19.9 7e-08 33.0 0.4 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS75545.1 - 8.7e-07 29.2 1.2 0.66 10.3 0.0 5.9 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 ETS75545.1 - 0.019 14.9 0.3 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS CSN8_PSD8_EIF3K PF10075.9 ETS75546.1 - 1.5e-16 60.7 0.0 2.7e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Sel1 PF08238.12 ETS75547.1 - 6.1e-17 61.7 25.3 8.2e-07 29.5 0.0 7.5 7 0 0 7 7 7 5 Sel1 repeat TPR_1 PF00515.28 ETS75547.1 - 0.001 18.8 3.0 0.001 18.8 0.2 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ETS75547.1 - 0.0051 16.8 0.1 0.0051 16.8 0.1 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 ETS75547.1 - 0.052 14.2 5.8 0.065 13.9 1.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ETS75547.1 - 0.062 14.0 4.6 0.71 10.6 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 ETS75547.1 - 0.12 12.4 0.2 0.36 11.0 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 ETS75547.1 - 0.2 12.0 0.1 0.2 12.0 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SNF2_N PF00176.23 ETS75548.1 - 1.2e-66 224.9 0.3 2.3e-66 223.9 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS75548.1 - 6.4e-18 65.1 0.0 4.3e-17 62.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ETS75548.1 - 5.5e-08 32.8 0.0 1.4e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ETS75548.1 - 2.5e-07 30.8 0.0 5.8e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ETS75548.1 - 0.00056 19.2 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_34 PF13872.6 ETS75548.1 - 0.012 14.5 0.1 0.041 12.8 0.1 1.9 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Zn-ribbon_8 PF09723.10 ETS75548.1 - 0.072 13.2 1.3 0.21 11.7 1.3 1.7 1 0 0 1 1 1 0 Zinc ribbon domain DEAD_2 PF06733.15 ETS75548.1 - 0.08 12.6 0.3 0.42 10.2 0.0 2.3 2 0 0 2 2 2 0 DEAD_2 Ank_2 PF12796.7 ETS75549.1 - 2.6e-13 50.4 2.6 0.00063 20.3 0.0 6.9 5 1 0 6 6 6 2 Ankyrin repeats (3 copies) NACHT PF05729.12 ETS75549.1 - 1.7e-10 41.1 0.0 3.9e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.6 ETS75549.1 - 1.5e-07 31.1 0.3 0.18 12.5 0.0 5.9 6 0 0 6 6 4 1 Ankyrin repeat AAA_22 PF13401.6 ETS75549.1 - 2.6e-07 31.0 0.0 9.4e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain Ank_4 PF13637.6 ETS75549.1 - 7.8e-07 29.5 0.0 0.0049 17.4 0.0 5.1 5 2 1 6 6 6 2 Ankyrin repeats (many copies) AAA_25 PF13481.6 ETS75549.1 - 4.6e-06 26.4 0.0 1.4e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ETS75549.1 - 2.5e-05 24.7 0.2 0.00013 22.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Ank PF00023.30 ETS75549.1 - 0.00017 21.9 0.1 0.082 13.4 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat NB-ARC PF00931.22 ETS75549.1 - 0.0026 17.0 0.2 0.015 14.5 0.1 2.3 2 1 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 ETS75549.1 - 0.0038 17.6 0.1 0.02 15.3 0.0 2.3 2 0 0 2 2 1 1 AAA ATPase domain MIEAP PF16026.5 ETS75549.1 - 0.029 14.6 0.2 0.029 14.6 0.2 3.0 3 0 0 3 3 3 0 Mitochondria-eating protein AAA_19 PF13245.6 ETS75549.1 - 0.03 14.6 0.2 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 ETS75549.1 - 0.046 13.0 0.0 0.21 10.8 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain Ank_5 PF13857.6 ETS75549.1 - 0.054 13.8 1.2 61 4.1 0.0 4.7 4 1 1 5 5 5 0 Ankyrin repeats (many copies) AAA_18 PF13238.6 ETS75549.1 - 0.11 13.0 0.5 0.72 10.4 0.1 2.8 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 ETS75549.1 - 0.13 12.3 0.0 0.41 10.7 0.0 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 ETS75549.1 - 0.21 11.3 1.0 0.71 9.6 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF2075 PF09848.9 ETS75549.1 - 0.51 9.5 3.5 17 4.5 0.3 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) 2OG-FeII_Oxy_3 PF13640.6 ETS75550.1 - 5.1e-07 30.5 0.0 9.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CDC45 PF02724.14 ETS75550.1 - 0.0026 16.1 10.3 0.0037 15.6 10.3 1.2 1 0 0 1 1 1 1 CDC45-like protein TIMELESS_C PF05029.13 ETS75550.1 - 0.015 14.5 13.9 0.023 13.9 13.9 1.2 1 0 0 1 1 1 0 Timeless protein C terminal region Sporozoite_P67 PF05642.11 ETS75550.1 - 0.034 12.3 9.5 0.048 11.8 9.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen eIF-3c_N PF05470.12 ETS75550.1 - 1.7 6.9 5.9 2.3 6.5 5.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus POX PF07526.11 ETS75550.1 - 2.1 8.9 4.5 4.9 7.7 4.5 1.5 1 0 0 1 1 1 0 Associated with HOX SDA1 PF05285.12 ETS75550.1 - 2.4 7.5 23.3 4.2 6.7 23.3 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 ETS75550.1 - 3.6 5.6 31.9 5.7 4.9 31.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Vfa1 PF08432.10 ETS75550.1 - 4.5 7.6 9.3 8 6.7 9.3 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Tub_N PF16322.5 ETS75550.1 - 5.4 7.4 18.8 11 6.4 18.8 1.4 1 0 0 1 1 1 0 Tubby N-terminal CFEM PF05730.11 ETS75552.1 - 7.3e-15 54.8 13.3 1.1e-14 54.3 13.3 1.3 1 0 0 1 1 1 1 CFEM domain SopE_GEF PF07487.13 ETS75552.1 - 0.23 11.6 4.5 0.44 10.7 4.5 1.5 1 0 0 1 1 1 0 SopE GEF domain peroxidase PF00141.23 ETS75553.1 - 8.2e-88 293.9 0.0 7.7e-46 156.6 0.0 2.1 2 0 0 2 2 2 2 Peroxidase Chitin_bind_1 PF00187.19 ETS75554.1 - 0.0017 18.8 16.3 0.0017 18.8 16.3 2.7 3 0 0 3 3 3 1 Chitin recognition protein PAN_4 PF14295.6 ETS75554.1 - 0.0021 17.9 1.3 0.0021 17.9 1.3 2.5 2 1 0 2 2 2 1 PAN domain Secretin PF00263.21 ETS75554.1 - 0.18 11.4 0.3 0.26 10.9 0.3 1.1 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein AAA PF00004.29 ETS75555.1 - 7.5e-16 58.8 0.0 1.3e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ETS75555.1 - 0.00016 21.2 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 ETS75555.1 - 0.0007 19.9 0.1 0.1 12.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain Bac_DnaA PF00308.18 ETS75555.1 - 0.004 17.0 0.0 0.007 16.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein RNA_helicase PF00910.22 ETS75555.1 - 0.0099 16.3 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Sigma54_activat PF00158.26 ETS75555.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 ETS75555.1 - 0.019 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 ETS75555.1 - 0.047 12.7 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 ETS75555.1 - 0.064 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ETS75555.1 - 0.064 13.6 0.1 0.28 11.6 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 ETS75555.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 ETS75555.1 - 0.11 12.5 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 ETS75555.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1289 PF06945.13 ETS75555.1 - 0.13 12.1 39.7 6.7 6.6 0.1 10.4 11 0 0 11 11 11 0 Protein of unknown function (DUF1289) ResIII PF04851.15 ETS75555.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4606 PF15379.6 ETS75555.1 - 0.29 11.4 12.2 60 3.9 0.0 6.7 2 1 3 7 7 7 0 Domain of unknown function (DUF4606) EB1 PF03271.17 ETS75557.1 - 1.4e-17 63.7 1.4 2.8e-17 62.7 1.4 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 ETS75557.1 - 1.7e-06 28.2 0.4 2.9e-06 27.4 0.4 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 ETS75557.1 - 0.064 13.4 0.2 0.1 12.7 0.2 1.3 1 0 0 1 1 1 0 CH-like domain in sperm protein adh_short PF00106.25 ETS75558.1 - 4e-16 59.1 0.0 8.7e-13 48.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 ETS75558.1 - 0.00033 20.6 0.4 0.0012 18.8 0.0 2.0 2 0 0 2 2 2 1 KR domain p450 PF00067.22 ETS75559.1 - 2.8e-53 181.3 0.0 3.6e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 ETS75560.1 - 1.2e-53 182.5 42.1 1.6e-53 182.1 42.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS75560.1 - 1.9e-16 59.7 36.2 2.8e-16 59.2 36.0 1.3 2 0 0 2 2 2 1 Amino acid permease MFS_1 PF07690.16 ETS75561.1 - 3.4e-39 134.8 28.7 3.4e-39 134.8 28.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily SpoVAB PF13782.6 ETS75561.1 - 0.029 14.7 2.1 0.029 14.7 2.1 2.6 3 0 0 3 3 3 0 Stage V sporulation protein AB Fungal_trans PF04082.18 ETS75562.1 - 4e-34 117.9 0.1 5.5e-34 117.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS75562.1 - 4.3e-06 26.7 12.5 9e-06 25.7 12.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2597 PF10772.9 ETS75562.1 - 0.044 13.8 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) Aldo_ket_red PF00248.21 ETS75563.1 - 1.7e-52 178.4 0.5 1.3e-51 175.5 0.5 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Phage_X PF05155.15 ETS75563.1 - 0.046 14.1 0.0 0.13 12.7 0.0 1.7 2 0 0 2 2 2 0 Phage X family NAD_binding_4 PF07993.12 ETS75564.1 - 5e-47 160.2 0.0 8.7e-47 159.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 ETS75564.1 - 3.5e-34 118.1 0.1 6.7e-34 117.2 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 ETS75564.1 - 6.2e-13 48.8 0.0 1.3e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 ETS75564.1 - 3.8e-09 36.8 0.0 4.3e-08 33.4 0.0 2.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site AAA_33 PF13671.6 ETS75564.1 - 7e-08 32.7 0.0 1.8e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 ETS75564.1 - 4.7e-07 30.1 0.0 1.8e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Shikimate kinase 3Beta_HSD PF01073.19 ETS75564.1 - 1.8e-06 27.2 0.0 3.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AAA_18 PF13238.6 ETS75564.1 - 1.9e-06 28.5 0.0 1.1e-05 25.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 ETS75564.1 - 2.1e-05 24.4 0.0 4.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase AAA_16 PF13191.6 ETS75564.1 - 0.00017 22.0 0.0 0.00077 19.9 0.0 2.1 3 0 0 3 3 1 1 AAA ATPase domain AAA_17 PF13207.6 ETS75564.1 - 0.00082 19.8 0.0 0.0027 18.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain KR PF08659.10 ETS75564.1 - 0.0013 18.7 0.1 0.0042 17.0 0.1 1.9 1 0 0 1 1 1 1 KR domain APS_kinase PF01583.20 ETS75564.1 - 0.0037 17.2 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase Semialdhyde_dh PF01118.24 ETS75564.1 - 0.012 16.0 0.0 0.033 14.6 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 ETS75564.1 - 0.012 14.7 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ETS75564.1 - 0.014 15.3 0.1 0.23 11.4 0.0 2.7 2 0 0 2 2 2 0 NAD(P)H-binding AAA_28 PF13521.6 ETS75564.1 - 0.034 14.4 0.1 0.12 12.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ETS75564.1 - 0.038 14.0 0.0 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 ETS75564.1 - 0.039 14.4 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 ETS75564.1 - 0.043 14.3 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 ETS75564.1 - 0.051 13.9 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ETS75564.1 - 0.055 13.4 0.0 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 ETS75564.1 - 0.073 12.8 0.0 0.25 11.1 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain NmrA PF05368.13 ETS75564.1 - 0.087 12.4 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 NmrA-like family AAA_PrkA PF08298.11 ETS75564.1 - 0.1 11.5 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain DapB_N PF01113.20 ETS75564.1 - 0.13 12.3 0.1 0.53 10.4 0.0 2.1 2 0 0 2 2 1 0 Dihydrodipicolinate reductase, N-terminus KAP_NTPase PF07693.14 ETS75564.1 - 0.16 11.1 0.0 0.57 9.4 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain DUF2183 PF09949.9 ETS75565.1 - 7.9e-32 109.5 0.0 4.6e-31 107.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 ETS75565.1 - 0.047 13.2 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Lipase_chap PF03280.14 ETS75565.1 - 7.1 6.5 10.2 8.9 6.2 3.5 2.4 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein DEAD PF00270.29 ETS75566.1 - 2.4e-48 164.2 0.3 7.1e-48 162.7 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS75566.1 - 4e-30 104.4 0.1 8.7e-29 100.1 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 ETS75566.1 - 8e-05 21.6 1.0 0.00032 19.6 0.1 2.2 1 1 2 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Fungal_trans PF04082.18 ETS75567.1 - 1.8e-33 115.7 0.0 2.6e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS75567.1 - 7.3e-06 26.0 10.3 7.3e-06 26.0 10.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transferase PF02458.15 ETS75568.1 - 0.0015 17.3 0.0 0.0018 17.0 0.0 1.0 1 0 0 1 1 1 1 Transferase family Transferase PF02458.15 ETS75569.1 - 1.9e-12 46.6 0.0 2.3e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Transferase family Glyco_hydro_61 PF03443.14 ETS75570.1 - 0.00017 21.6 0.1 0.00017 21.6 0.1 1.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 ETS75570.1 - 0.00054 20.7 1.4 0.0011 19.7 0.0 2.0 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Tyrosinase PF00264.20 ETS75571.1 - 4.2e-34 118.8 0.2 7.2e-34 118.0 0.2 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF3593 PF12159.8 ETS75573.1 - 0.31 11.1 4.7 2.1 8.4 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3593) NACHT PF05729.12 ETS75574.1 - 2.5e-18 66.5 0.9 4e-15 56.1 0.0 3.1 3 0 0 3 3 3 2 NACHT domain HEAT_2 PF13646.6 ETS75574.1 - 6.1e-17 61.8 6.8 0.00067 20.0 0.1 6.4 5 1 1 6 6 6 4 HEAT repeats HEAT PF02985.22 ETS75574.1 - 8e-07 28.8 5.2 0.003 17.7 0.0 6.8 8 0 0 8 8 8 1 HEAT repeat AAA_22 PF13401.6 ETS75574.1 - 1.3e-05 25.5 0.6 0.0041 17.4 0.0 4.3 4 0 0 4 4 4 1 AAA domain HEAT_EZ PF13513.6 ETS75574.1 - 2.8e-05 24.5 0.6 0.35 11.4 0.0 5.7 5 0 0 5 5 5 1 HEAT-like repeat NB-ARC PF00931.22 ETS75574.1 - 0.00017 20.9 0.0 0.00039 19.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain NLRC4_HD2 PF17776.1 ETS75574.1 - 0.00018 22.1 0.0 0.00076 20.0 0.0 2.2 1 0 0 1 1 1 1 NLRC4 helical domain HD2 RasGEF_N_2 PF14663.6 ETS75574.1 - 0.0008 19.8 4.8 10 6.6 0.2 5.2 5 1 0 5 5 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain AAA_16 PF13191.6 ETS75574.1 - 0.0013 19.2 0.0 0.018 15.5 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 ETS75574.1 - 0.0087 16.1 0.0 0.034 14.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETS75574.1 - 0.01 16.4 0.0 0.18 12.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ETS75574.1 - 0.084 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 ETS75574.1 - 0.092 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cohesin_HEAT PF12765.7 ETS75574.1 - 0.096 13.0 1.0 2.2 8.7 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion TsaE PF02367.17 ETS75574.1 - 0.13 12.2 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 ETS75574.1 - 0.24 11.4 0.4 30 4.6 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Glyco_hydro_106 PF17132.4 ETS75576.1 - 1.2e-34 119.7 0.9 1.1e-29 103.3 0.0 2.2 1 1 1 2 2 2 2 alpha-L-rhamnosidase FAD_binding_4 PF01565.23 ETS75577.1 - 5.5e-18 65.1 1.2 8.2e-18 64.5 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS75577.1 - 6.9e-06 26.1 0.0 1.6e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 ETS75578.1 - 5.2e-44 150.8 0.0 7.4e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 ETS75579.1 - 5.8e-43 147.2 46.6 5.8e-43 147.2 46.6 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS75579.1 - 2.3e-13 49.5 11.0 3.6e-13 48.8 11.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS75579.1 - 8.7e-11 41.3 13.6 8.7e-11 41.3 13.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3522 PF12036.8 ETS75579.1 - 0.015 15.6 4.2 0.067 13.5 0.9 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3522) FAD_binding_4 PF01565.23 ETS75580.1 - 1.7e-25 89.3 0.1 2.6e-25 88.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS75580.1 - 0.059 13.5 0.4 0.14 12.3 0.4 1.7 1 0 0 1 1 1 0 Berberine and berberine like Death PF00531.22 ETS75580.1 - 0.15 12.2 0.1 0.36 11.0 0.1 1.6 1 0 0 1 1 1 0 Death domain Ank_2 PF12796.7 ETS75581.1 - 9.1e-13 48.6 0.8 0.00029 21.4 0.0 4.6 3 1 3 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS75581.1 - 2.7e-10 40.6 0.8 0.6 10.8 0.0 5.3 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS75581.1 - 4.6e-09 35.8 0.1 3.1 8.7 0.0 6.7 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 ETS75581.1 - 0.00015 22.0 1.5 2 8.8 0.1 4.2 3 2 1 5 5 5 3 Ankyrin repeats (many copies) DUF3265 PF11665.8 ETS75581.1 - 0.55 10.5 2.7 0.3 11.3 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3265) Abhydrolase_3 PF07859.13 ETS75582.1 - 2.3e-24 86.5 1.6 4.2e-20 72.5 0.2 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS75582.1 - 4.3e-10 39.4 0.3 1.3e-06 28.1 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 ETS75582.1 - 6.9e-05 23.6 6.4 9.7e-05 23.1 6.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 ETS75582.1 - 9.8e-05 21.4 0.0 0.00014 20.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 ETS75582.1 - 0.0012 17.9 0.0 0.0017 17.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 ETS75582.1 - 0.0028 17.0 0.1 0.45 9.7 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 ETS75582.1 - 0.0051 16.6 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.18 ETS75582.1 - 0.0069 16.0 0.1 0.033 13.7 0.1 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 ETS75582.1 - 0.038 13.5 0.0 4.2 6.9 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_4 PF08386.10 ETS75582.1 - 0.077 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF2920 PF11144.8 ETS75582.1 - 0.091 11.9 0.0 10 5.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) HCV_NS4a PF01006.20 ETS75583.1 - 0.46 10.3 1.7 1.4 8.7 1.7 1.8 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a Pro_isomerase PF00160.21 ETS75584.1 - 1.5e-42 145.6 0.8 1.7e-42 145.4 0.8 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_M43 PF05572.13 ETS75585.1 - 9.4e-11 41.8 0.5 2e-10 40.8 0.2 1.6 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 ETS75585.1 - 0.00012 22.3 0.7 0.00028 21.1 0.7 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 ETS75585.1 - 0.0015 18.2 0.2 0.0046 16.6 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 ETS75585.1 - 0.0032 18.0 0.1 0.015 15.8 0.1 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 ETS75585.1 - 0.0036 17.2 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 ETS75585.1 - 0.0041 16.1 0.5 0.0068 15.4 0.5 1.3 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_2 PF13574.6 ETS75585.1 - 0.0084 16.0 0.1 0.019 14.9 0.1 1.5 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like DUF5026 PF16429.5 ETS75585.1 - 0.011 15.9 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5026) Peptidase_M7 PF02031.16 ETS75585.1 - 0.039 14.1 0.1 0.071 13.2 0.1 1.4 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family DUF4953 PF16313.5 ETS75585.1 - 0.077 12.2 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Metallopep PF12044.8 ETS75585.1 - 0.92 8.0 2.2 1.4 7.5 2.2 1.1 1 0 0 1 1 1 0 Putative peptidase family DHDPS PF00701.22 ETS75586.1 - 1.1e-31 109.7 0.0 1.4e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF818 PF05677.12 ETS75586.1 - 0.092 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) MR_MLE_C PF13378.6 ETS75587.1 - 4.9e-59 199.5 0.0 6.1e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ETS75587.1 - 3.9e-15 56.1 0.0 7.7e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Cyclase PF04199.13 ETS75588.1 - 2.4e-12 47.3 0.0 4.6e-12 46.4 0.0 1.4 1 1 0 1 1 1 1 Putative cyclase DUF3262 PF11660.8 ETS75589.1 - 0.099 13.0 0.3 0.17 12.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) DUF1270 PF06900.11 ETS75589.1 - 0.14 12.6 0.3 0.26 11.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1270) Pectate_lyase PF03211.13 ETS75590.1 - 1.8e-79 266.0 6.0 2.1e-79 265.8 6.0 1.0 1 0 0 1 1 1 1 Pectate lyase DNA_methylase PF00145.17 ETS75591.1 - 1.6e-31 109.9 0.0 3.1e-31 108.9 0.0 1.5 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 ETS75591.1 - 0.00061 19.6 0.0 0.0049 16.7 0.0 2.2 2 0 0 2 2 2 1 BAH domain DUF155 PF02582.14 ETS75592.1 - 2.7e-42 144.9 0.2 5.1e-42 143.9 0.0 1.5 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Sec7 PF01369.20 ETS75594.1 - 5e-27 94.8 0.0 1.7e-26 93.0 0.0 1.8 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 ETS75594.1 - 7e-19 68.3 0.0 1.6e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DUF2076 PF09849.9 ETS75594.1 - 0.19 11.8 6.1 0.65 10.0 6.1 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) NAD_binding_8 PF13450.6 ETS75595.1 - 1.2e-09 38.2 0.0 3.1e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 ETS75595.1 - 4.4e-08 32.0 0.0 1.1e-06 27.4 0.0 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 ETS75595.1 - 0.0097 15.9 0.3 0.28 11.2 0.0 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding Lactamase_B PF00753.27 ETS75596.1 - 8e-22 78.2 0.6 2.5e-21 76.6 0.6 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS75596.1 - 2.2e-07 30.6 0.1 2.9e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Fungal_trans PF04082.18 ETS75597.1 - 0.015 14.3 0.1 0.045 12.8 0.0 1.9 1 1 0 1 1 1 0 Fungal specific transcription factor domain Cu-oxidase PF00394.22 ETS75598.1 - 2e-34 119.0 0.0 1.2e-31 110.0 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ETS75598.1 - 3.5e-29 101.2 1.1 3.5e-29 101.2 1.1 2.2 2 1 1 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ETS75598.1 - 1.6e-20 73.3 12.9 2.3e-20 72.7 3.2 3.5 2 2 0 2 2 2 2 Multicopper oxidase Solute_trans_a PF03619.16 ETS75599.1 - 7.9e-54 183.0 13.2 9.5e-54 182.7 13.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha CFEM PF05730.11 ETS75600.1 - 2.7e-10 40.2 4.7 4.2e-10 39.6 4.7 1.3 1 0 0 1 1 1 1 CFEM domain Peptidase_C34 PF05413.11 ETS75600.1 - 0.04 14.2 0.5 0.057 13.7 0.5 1.3 1 0 0 1 1 1 0 Putative closterovirus papain-like endopeptidase Acyl_transf_3 PF01757.22 ETS75601.1 - 2.6e-23 82.6 29.4 7.7e-23 81.1 29.1 1.9 1 1 0 1 1 1 1 Acyltransferase family DUF2975 PF11188.8 ETS75601.1 - 4.8 7.1 5.9 0.56 10.1 0.5 2.2 2 2 0 2 2 2 0 Protein of unknown function (DUF2975) Glyco_transf_20 PF00982.21 ETS75603.1 - 4.1e-147 490.7 0.0 6.2e-147 490.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ETS75603.1 - 2.3e-71 239.6 0.0 4.8e-71 238.6 0.0 1.6 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 ETS75603.1 - 0.014 15.2 0.1 0.75 9.5 0.0 2.5 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Glycos_transf_1 PF00534.20 ETS75603.1 - 0.099 12.2 0.0 1.2 8.7 0.0 2.5 3 0 0 3 3 3 0 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 ETS75603.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain MFS_1 PF07690.16 ETS75604.1 - 2e-37 129.0 49.3 9.1e-37 126.8 47.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS75604.1 - 3.3e-16 58.8 12.2 3.3e-16 58.8 12.2 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS75604.1 - 5.7e-10 38.6 10.8 5.7e-10 38.6 10.8 2.9 1 1 1 3 3 3 1 Sugar (and other) transporter YrhK PF14145.6 ETS75604.1 - 0.44 10.5 0.0 0.44 10.5 0.0 3.6 3 1 0 3 3 3 0 YrhK-like protein PS-DH PF14765.6 ETS75605.1 - 1.5e-62 211.6 0.0 2.5e-62 210.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 ETS75605.1 - 6.3e-60 202.9 0.0 2.2e-59 201.1 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ETS75605.1 - 6.4e-60 202.1 0.7 1.6e-59 200.9 0.1 2.0 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 ETS75605.1 - 1.3e-54 185.9 1.9 2.2e-54 185.1 1.9 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ETS75605.1 - 2.5e-32 111.4 0.2 5.8e-32 110.2 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ETS75605.1 - 2.2e-22 79.7 0.0 1.7e-21 76.8 0.0 2.7 3 0 0 3 3 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ETS75605.1 - 4.6e-18 65.7 0.0 1.3e-17 64.3 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 ETS75605.1 - 9.5e-17 62.3 0.0 4.1e-16 60.2 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ETS75605.1 - 2.2e-16 60.0 0.0 1e-15 57.9 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 ETS75605.1 - 8.8e-13 48.8 0.0 3.6e-11 43.6 0.0 3.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS75605.1 - 6.6e-12 45.5 0.0 3.6e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS75605.1 - 2.2e-11 44.2 0.0 9e-11 42.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 ETS75605.1 - 9.6e-10 38.2 0.6 6e-09 35.6 0.1 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 ETS75605.1 - 2e-09 37.5 0.5 7.2e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.12 ETS75605.1 - 6.8e-09 35.6 0.7 1.8e-08 34.2 0.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 ETS75605.1 - 1e-07 31.8 0.0 2.5e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 ETS75605.1 - 1.8e-06 28.2 0.2 5.2e-06 26.7 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 ETS75605.1 - 0.0012 18.2 0.7 0.0043 16.4 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 ETS75605.1 - 0.0066 16.2 0.0 0.24 11.1 0.0 2.8 2 1 0 2 2 2 1 Lysine methyltransferase Methyltransf_33 PF10017.9 ETS75605.1 - 0.042 13.0 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Ubie_methyltran PF01209.18 ETS75605.1 - 0.064 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 ETS75605.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Shikimate_DH PF01488.20 ETS75605.1 - 0.16 12.0 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1996 PF09362.10 ETS75608.1 - 7.9e-46 157.0 0.5 9.5e-46 156.7 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) SGL PF08450.12 ETS75609.1 - 0.00026 20.6 0.0 0.0037 16.9 0.0 2.2 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region p450 PF00067.22 ETS75610.1 - 6.6e-57 193.3 0.0 9.8e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 CsbD PF05532.12 ETS75611.1 - 0.49 10.3 20.3 2.5 8.1 14.4 3.2 2 1 0 2 2 2 0 CsbD-like DUF883 PF05957.13 ETS75611.1 - 0.81 10.3 7.9 0.83 10.3 2.8 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) MT0933_antitox PF14013.6 ETS75611.1 - 1 9.7 17.9 1.5 9.2 3.1 2.5 2 1 0 2 2 2 0 MT0933-like antitoxin protein Pkinase PF00069.25 ETS75612.1 - 2.8e-10 40.0 0.0 1.8e-07 30.8 0.0 3.3 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS75612.1 - 1e-06 28.2 0.0 0.032 13.5 0.0 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase UDPGT PF00201.18 ETS75613.1 - 0.03 13.1 0.0 0.11 11.2 0.0 1.7 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase ECH_1 PF00378.20 ETS75615.1 - 1.2e-38 132.9 0.2 1.1e-35 123.2 0.1 2.8 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ETS75615.1 - 2.9e-24 86.2 0.1 3e-23 82.8 0.1 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ank_2 PF12796.7 ETS75616.1 - 1.6e-13 51.0 0.0 2.3e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS75616.1 - 2.4e-12 47.1 0.8 3.5e-07 30.6 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS75616.1 - 3.1e-11 42.4 0.0 5.3e-06 26.4 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 ETS75616.1 - 1.3e-10 41.2 0.3 2.6e-07 30.8 0.4 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ETS75616.1 - 4.7e-10 39.5 0.4 9.8e-10 38.5 0.3 1.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Fungal_trans_2 PF11951.8 ETS75617.1 - 3.6e-07 29.4 1.1 0.00061 18.7 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS75617.1 - 0.0022 18.1 14.6 0.0045 17.1 14.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ETS75618.1 - 2e-32 112.5 36.7 1.2e-31 109.9 37.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS75618.1 - 2.3e-05 23.9 4.1 2.3e-05 23.9 4.1 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB RNase_H PF00075.24 ETS75619.1 - 8.3e-21 74.7 0.0 1.1e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 ETS75619.1 - 8.1e-07 28.9 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase-like RNase_H PF00075.24 ETS75620.1 - 9.2e-14 51.8 0.0 6.7e-13 49.0 0.0 1.9 1 1 1 2 2 2 1 RNase H RVT_3 PF13456.6 ETS75620.1 - 0.00024 20.9 0.0 0.031 14.1 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase-like YL1 PF05764.13 ETS75620.1 - 3.5 7.7 6.3 4.9 7.2 6.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Kinesin PF00225.23 ETS75621.1 - 2.6e-80 269.8 0.1 3.7e-80 269.4 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ETS75621.1 - 2.3e-20 73.1 0.0 4e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding HHH_3 PF12836.7 ETS75621.1 - 7.7e-06 26.1 0.5 3.6e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 ETS75621.1 - 0.0097 16.5 0.6 0.079 13.6 0.0 2.7 3 0 0 3 3 3 1 Helix-hairpin-helix domain HHH_7 PF14635.6 ETS75621.1 - 0.014 15.7 0.0 0.09 13.1 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif MerR-DNA-bind PF09278.11 ETS75621.1 - 2.6 8.7 6.3 0.94 10.1 1.9 2.5 2 0 0 2 2 2 0 MerR, DNA binding MFS_1 PF07690.16 ETS75622.1 - 3.1e-38 131.6 35.2 3.1e-38 131.6 35.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS75622.1 - 0.00015 20.3 3.3 0.00024 19.7 3.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BNIP3 PF06553.12 ETS75622.1 - 0.057 13.1 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 BNIP3 MlaA PF04333.13 ETS75622.1 - 1.1 8.9 2.9 0.36 10.5 0.1 1.6 2 0 0 2 2 2 0 MlaA lipoprotein DUF4979 PF16351.5 ETS75623.1 - 0.12 12.5 0.0 0.27 11.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4979) Abhydrolase_3 PF07859.13 ETS75624.1 - 1.5e-42 145.9 0.0 1.8e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS75624.1 - 5.7e-06 26.0 0.6 0.0055 16.2 0.1 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family DLH PF01738.18 ETS75624.1 - 0.00012 21.8 0.0 0.0096 15.5 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 ETS75624.1 - 0.0021 17.9 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 ETS75624.1 - 0.0026 17.7 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2974 PF11187.8 ETS75624.1 - 0.0029 17.2 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) AXE1 PF05448.12 ETS75624.1 - 0.005 15.5 0.1 0.012 14.3 0.0 1.6 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 ETS75624.1 - 0.0063 16.0 0.2 0.26 10.8 0.1 2.3 2 0 0 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.20 ETS75624.1 - 0.013 15.1 1.1 0.27 10.8 1.1 2.1 1 1 0 1 1 1 0 Putative esterase COesterase PF00135.28 ETS75624.1 - 0.016 14.1 0.3 0.14 11.0 0.2 2.1 2 1 0 2 2 2 0 Carboxylesterase family Abhydrolase_6 PF12697.7 ETS75624.1 - 0.035 14.7 8.0 0.04 14.5 7.2 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 ETS75624.1 - 0.081 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain zf-C2H2_2 PF12756.7 ETS75625.1 - 1.3e-24 86.5 3.6 2e-24 85.8 3.6 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 ETS75626.1 - 7.1e-08 32.5 25.4 0.00028 21.1 7.0 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS75626.1 - 2.4e-07 31.0 16.4 0.011 16.5 6.0 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ETS75626.1 - 4.8e-07 29.9 12.3 0.0017 18.7 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 ETS75626.1 - 0.016 15.0 8.4 0.14 12.0 2.6 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type C1_4 PF07975.12 ETS75626.1 - 3.7 7.9 8.5 8.3 6.7 8.5 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain Zn_ribbon_SprT PF17283.2 ETS75626.1 - 5.2 7.1 9.3 29 4.7 8.0 2.7 1 1 1 2 2 2 0 SprT-like zinc ribbon domain p450 PF00067.22 ETS75628.1 - 1.8e-41 142.4 0.0 2.3e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PAS_11 PF14598.6 ETS75628.1 - 0.18 12.0 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 PAS domain DUF5615 PF18480.1 ETS75629.1 - 0.12 12.2 0.1 0.56 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) WSC PF01822.19 ETS75630.1 - 5.9e-10 39.2 9.1 5.9e-10 39.2 9.1 1.8 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.10 ETS75630.1 - 3.9e-07 29.4 2.7 3.9e-07 29.4 2.7 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Alpha_GJ PF03229.13 ETS75630.1 - 0.0073 16.9 4.2 0.016 15.8 4.2 1.5 1 0 0 1 1 1 1 Alphavirus glycoprotein J DUF4448 PF14610.6 ETS75630.1 - 0.018 14.8 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Nitrate_red_gam PF02665.14 ETS75630.1 - 0.027 14.0 0.1 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Tmemb_cc2 PF10267.9 ETS75630.1 - 0.051 12.7 0.7 0.062 12.4 0.7 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein MGC-24 PF05283.11 ETS75630.1 - 3.5 8.1 13.5 0.63 10.5 9.6 1.6 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ank_5 PF13857.6 ETS75632.1 - 2.3e-23 81.9 6.3 2e-06 28.0 0.1 7.1 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS75632.1 - 5.5e-22 78.2 0.0 2.4e-05 24.8 0.1 5.6 4 2 0 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS75632.1 - 4.3e-18 65.4 1.9 0.0012 19.4 0.2 6.9 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS75632.1 - 9.4e-18 62.5 6.8 0.0031 17.9 0.0 8.8 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 ETS75632.1 - 1.3e-16 60.2 10.0 0.00011 22.4 0.0 8.2 9 0 0 9 9 9 4 Ankyrin repeat HTH_18 PF12833.7 ETS75632.1 - 0.16 12.2 0.0 26 5.2 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain DUF3247 PF11607.8 ETS75632.1 - 0.2 11.9 1.2 2.6 8.4 0.0 3.3 4 1 1 5 5 5 0 Protein of unknown function (DUF3247) W2 PF02020.18 ETS75633.1 - 9e-21 73.8 0.8 2.8e-20 72.2 0.8 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 ETS75633.1 - 1.6e-11 43.4 4.3 0.00028 20.5 0.3 3.8 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ETS75633.1 - 1.4e-07 31.1 1.1 0.0052 16.5 0.2 2.9 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 ETS75633.1 - 2.9e-05 22.4 0.3 5.3e-05 21.6 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 ETS75633.1 - 0.00016 20.7 0.1 0.00054 19.0 0.1 1.7 1 1 0 1 1 1 1 L-fucokinase NTP_transferase PF00483.23 ETS75633.1 - 0.0019 17.8 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ETS75633.1 - 0.02 15.2 0.0 0.052 13.9 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain Rft-1 PF04506.13 ETS75633.1 - 0.094 11.4 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Rft protein HSF_DNA-bind PF00447.17 ETS75634.1 - 3e-28 98.3 2.5 7.2e-28 97.1 2.5 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 ETS75634.1 - 3.2e-22 78.8 0.2 8.5e-22 77.4 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain CENP-H PF05837.12 ETS75634.1 - 0.012 16.0 4.3 0.027 14.9 4.3 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) V_ATPase_I PF01496.19 ETS75634.1 - 0.018 13.0 4.5 0.023 12.6 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PK_C PF02887.16 ETS75634.1 - 0.17 12.1 0.0 0.54 10.5 0.0 1.8 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain DASH_Dad2 PF08654.10 ETS75634.1 - 0.29 11.6 2.3 2 8.9 2.3 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad2 YabA PF06156.13 ETS75634.1 - 1.3 9.7 3.3 2.8 8.6 3.3 1.6 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 ETS75634.1 - 1.7 9.2 4.7 4.1 7.9 4.7 1.7 1 1 0 1 1 1 0 Cell division protein ZapB DUF3450 PF11932.8 ETS75634.1 - 2.6 7.3 7.8 4.2 6.6 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) LMBR1 PF04791.16 ETS75634.1 - 4.1 6.2 3.9 5.6 5.7 3.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GIT_CC PF16559.5 ETS75634.1 - 5.9 6.8 9.4 3.1 7.7 0.6 2.4 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor COesterase PF00135.28 ETS75635.1 - 4.1e-90 303.1 0.7 1.5e-79 268.3 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS75635.1 - 5.5e-12 46.0 0.1 8.5e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1180 PF06679.12 ETS75636.1 - 0.00081 19.9 0.5 0.0014 19.0 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1180) RCR PF12273.8 ETS75636.1 - 0.0079 16.8 0.5 0.0079 16.8 0.5 1.6 2 1 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red TMEM132D_C PF15706.5 ETS75636.1 - 0.13 12.0 0.2 0.25 11.1 0.2 1.6 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term FAD_binding_3 PF01494.19 ETS75637.1 - 3.6e-78 263.3 0.1 4.5e-78 263.0 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 ETS75637.1 - 1.3e-45 155.4 0.0 3.3e-45 154.1 0.0 1.7 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 ETS75637.1 - 5.7e-07 29.4 1.5 2.7e-05 23.9 1.5 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ETS75637.1 - 0.00033 20.1 0.4 0.0066 15.8 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS75637.1 - 0.0011 18.2 0.5 0.0078 15.3 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS75637.1 - 0.008 15.4 0.3 0.19 10.9 0.4 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS75637.1 - 0.0092 15.2 0.1 0.017 14.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 ETS75637.1 - 0.034 14.4 0.2 0.1 12.8 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 ETS75637.1 - 0.051 12.6 0.0 5 6.1 0.0 2.3 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.6 ETS75637.1 - 0.069 12.4 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS75637.1 - 0.1 11.6 0.1 0.69 8.9 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A PIP5K PF01504.18 ETS75638.1 - 2.5e-45 154.9 0.0 3.6e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase TPR_10 PF13374.6 ETS75640.1 - 2.8e-61 201.8 14.6 1.7e-09 37.3 0.2 8.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 ETS75640.1 - 6.8e-60 199.3 32.4 4.9e-13 49.2 2.5 6.4 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 ETS75640.1 - 1.4e-12 46.7 9.2 0.011 15.7 0.0 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat HET PF06985.11 ETS75640.1 - 2.1e-10 41.1 7.6 2.2e-10 41.0 0.3 3.0 2 1 1 3 3 3 1 Heterokaryon incompatibility protein (HET) TPR_2 PF07719.17 ETS75640.1 - 7.8e-10 38.1 4.3 0.083 13.1 0.1 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS75640.1 - 3.1e-09 36.7 10.3 0.00015 21.3 0.2 3.2 1 1 2 3 3 3 3 MalT-like TPR region TPR_17 PF13431.6 ETS75640.1 - 2.9e-08 33.5 1.5 0.31 11.5 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 ETS75640.1 - 2e-07 30.5 6.9 0.2 11.6 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 ETS75640.1 - 2.8e-07 30.2 4.3 2.7 8.4 0.2 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat NB-ARC PF00931.22 ETS75640.1 - 3.9e-07 29.5 0.0 8.5e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 ETS75640.1 - 1.3e-05 25.5 0.0 7.8e-05 23.0 0.0 2.3 2 0 0 2 2 1 1 AAA domain TPR_19 PF14559.6 ETS75640.1 - 3.5e-05 24.2 3.9 2.7 8.6 0.3 5.5 3 2 3 6 6 6 2 Tetratricopeptide repeat AAA_16 PF13191.6 ETS75640.1 - 4.7e-05 23.8 1.3 0.00016 22.1 0.2 2.5 2 1 0 2 2 2 1 AAA ATPase domain TPR_14 PF13428.6 ETS75640.1 - 0.0025 18.5 7.0 1.2e+02 3.9 0.1 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat NACHT PF05729.12 ETS75640.1 - 0.0047 16.8 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_4 PF07721.14 ETS75640.1 - 0.015 15.8 0.0 47 5.0 0.0 4.7 4 1 1 5 5 3 0 Tetratricopeptide repeat ResIII PF04851.15 ETS75640.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 ETS75640.1 - 0.11 12.9 0.0 1.5 9.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF4404 PF14357.6 ETS75640.1 - 0.17 12.5 6.0 22 5.8 0.1 4.6 3 1 2 5 5 5 0 Domain of unknown function (DUF4404) TPR_6 PF13174.6 ETS75640.1 - 0.23 12.2 2.6 69 4.4 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS75640.1 - 1.9 8.8 10.5 2.7 8.3 0.4 5.2 3 2 3 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3500 PF12006.8 ETS75641.1 - 4.9e-74 249.5 0.0 5.7e-71 239.4 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3500) Methyltransf_2 PF00891.18 ETS75643.1 - 1.7e-21 76.5 0.0 3.3e-21 75.5 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 ETS75643.1 - 0.0048 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain Amino_oxidase PF01593.24 ETS75644.1 - 1.7e-60 205.6 0.1 4.9e-59 200.8 0.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ETS75644.1 - 5.5e-11 42.5 0.2 2.4e-10 40.5 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ETS75644.1 - 0.00015 21.0 0.2 0.00028 20.1 0.2 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 ETS75644.1 - 0.00089 18.9 0.0 0.0028 17.3 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS75644.1 - 0.0031 18.0 0.2 0.092 13.3 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS75644.1 - 0.0035 16.6 0.1 0.0098 15.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS75644.1 - 0.0039 16.5 0.1 0.007 15.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ETS75644.1 - 0.0051 16.2 1.0 0.0091 15.4 1.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ETS75644.1 - 0.0071 15.6 0.4 0.034 13.4 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 ETS75644.1 - 0.0077 15.5 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Shikimate_DH PF01488.20 ETS75644.1 - 0.011 15.8 0.1 0.033 14.3 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 ETS75644.1 - 0.044 12.9 1.3 0.067 12.3 1.3 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 ETS75644.1 - 0.056 12.7 0.2 0.12 11.6 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 ETS75644.1 - 0.15 12.0 0.3 5.6 6.9 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 ETS75644.1 - 0.19 10.4 0.1 0.3 9.8 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein AA_permease_2 PF13520.6 ETS75645.1 - 2e-52 178.4 49.4 2.5e-52 178.1 49.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS75645.1 - 1.1e-19 70.5 41.2 1.4e-19 70.0 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 ETS75647.1 - 2.9e-26 92.4 0.0 4.5e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS75647.1 - 6.8e-16 58.3 0.0 1.1e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ETS75647.1 - 0.071 13.0 0.4 4.9 7.0 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 ETS75647.1 - 0.16 10.9 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 ETS75648.1 - 1.4e-21 77.0 0.0 2.3e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS75648.1 - 1.3e-13 50.8 0.0 2.1e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 ETS75648.1 - 0.026 13.5 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HET PF06985.11 ETS75649.1 - 1.8e-17 64.1 0.0 3.2e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_61 PF03443.14 ETS75650.1 - 7.3e-59 199.2 0.0 7.3e-59 199.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Mucin PF01456.17 ETS75650.1 - 0.0028 17.7 24.8 0.0052 16.8 24.8 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein Med3 PF11593.8 ETS75650.1 - 1.2 8.2 24.8 1.6 7.8 24.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PAP1 PF08601.10 ETS75650.1 - 1.4 8.6 13.3 1.8 8.2 13.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 DUF3316 PF11777.8 ETS75650.1 - 1.7 8.7 0.0 1.7 8.7 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3316) PBD PF00786.28 ETS75651.1 - 0.0014 19.0 0.1 0.0063 16.8 0.1 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain S1 PF00575.23 ETS75652.1 - 1.6e-79 262.2 39.3 2.7e-12 46.9 0.2 13.2 13 0 0 13 13 13 11 S1 RNA binding domain Suf PF05843.14 ETS75652.1 - 1.6e-07 31.6 7.9 6.8e-05 23.0 0.1 4.3 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) RNase_II_C_S1 PF18614.1 ETS75652.1 - 4.3e-06 26.6 1.0 0.087 12.8 0.1 5.7 5 0 0 5 5 5 1 RNase II-type exonuclease C-terminal S1 domain TPR_14 PF13428.6 ETS75652.1 - 7.6e-06 26.3 0.6 2.6 9.1 0.0 5.6 3 1 3 6 6 5 1 Tetratricopeptide repeat S1_2 PF13509.6 ETS75652.1 - 0.00072 19.6 0.0 29 4.8 0.0 5.4 5 0 0 5 5 5 0 S1 domain NRDE-2 PF08424.10 ETS75652.1 - 0.00073 18.8 2.0 0.06 12.5 0.1 3.3 2 1 1 3 3 3 1 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 ETS75652.1 - 0.0016 18.9 2.1 1.1 9.8 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat SDA1 PF05285.12 ETS75652.1 - 0.002 17.6 23.4 0.002 17.6 23.4 3.5 3 1 0 4 4 4 1 SDA1 PG_binding_2 PF08823.11 ETS75652.1 - 0.067 13.5 0.3 0.43 10.9 0.1 2.6 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Arc_PepC PF06819.11 ETS75652.1 - 0.074 13.2 0.5 2.6 8.2 0.1 3.8 4 0 0 4 4 4 0 Archaeal Peptidase A24 C-terminal Domain Nop14 PF04147.12 ETS75652.1 - 0.95 7.6 29.1 2.7 6.1 29.1 1.8 1 0 0 1 1 1 0 Nop14-like family Fmp27 PF10344.9 ETS75654.1 - 9.7e-222 738.6 0.0 1.4e-221 738.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 ETS75654.1 - 6.4e-204 678.2 4.8 6.4e-204 678.2 4.8 2.7 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 ETS75654.1 - 5.1e-184 612.7 0.0 1.1e-183 611.6 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 ETS75654.1 - 2.8e-58 196.5 0.0 7.2e-58 195.1 0.0 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 ETS75654.1 - 1.8e-52 177.3 0.0 4.1e-52 176.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 ETS75654.1 - 1.6e-35 121.9 0.1 1.1e-34 119.2 0.0 2.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Serine_rich PF08824.10 ETS75654.1 - 0.037 14.0 1.3 0.14 12.2 0.2 2.5 2 0 0 2 2 2 0 Serine rich protein interaction domain Glyco_hydro_16 PF00722.21 ETS75655.1 - 5.9e-10 38.9 0.6 8.7e-10 38.3 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WW PF00397.26 ETS75656.1 - 5.3e-09 36.0 4.7 1.4e-08 34.6 4.7 1.8 1 0 0 1 1 1 1 WW domain WRW PF10206.9 ETS75656.1 - 0.009 16.4 0.4 0.025 14.9 0.2 1.8 2 0 0 2 2 2 1 Mitochondrial F1F0-ATP synthase, subunit f SKG6 PF08693.10 ETS75657.1 - 0.00038 19.8 1.1 0.00038 19.8 1.1 2.5 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Cytomega_TRL10 PF06084.11 ETS75657.1 - 0.036 14.1 0.2 0.089 12.8 0.2 1.7 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein DUF1180 PF06679.12 ETS75657.1 - 0.055 13.9 4.0 0.13 12.7 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF2207 PF09972.9 ETS75657.1 - 0.13 11.0 0.1 0.24 10.1 0.0 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) YajC PF02699.15 ETS75657.1 - 0.22 11.4 0.1 0.35 10.8 0.1 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit MGC-24 PF05283.11 ETS75657.1 - 0.53 10.7 22.0 18 5.8 22.0 2.3 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.6 ETS75657.1 - 0.79 9.6 7.6 3.1 7.7 7.5 1.8 1 1 0 1 1 1 0 TMEM154 protein family Proteasome PF00227.26 ETS75658.1 - 2.2e-57 193.7 0.2 3.3e-57 193.1 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ETS75658.1 - 1e-11 44.3 0.4 3.6e-11 42.5 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature zf-CHY PF05495.12 ETS75659.1 - 1.5e-11 44.6 20.1 2.6e-11 43.9 20.1 1.3 1 0 0 1 1 1 1 CHY zinc finger DiS_P_DiS PF06750.13 ETS75659.1 - 3.8 7.7 8.5 9.1 6.5 4.8 2.2 1 1 1 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Zn-ribbon_8 PF09723.10 ETS75659.1 - 6.8 6.9 23.0 0.17 12.0 9.1 2.7 2 1 0 3 3 3 0 Zinc ribbon domain DUF2457 PF10446.9 ETS75660.1 - 0.0049 16.1 11.7 0.0062 15.7 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) BUD22 PF09073.10 ETS75660.1 - 0.42 9.9 15.3 0.54 9.5 15.3 1.0 1 0 0 1 1 1 0 BUD22 TRAP_alpha PF03896.16 ETS75660.1 - 0.76 8.9 5.5 0.19 10.9 0.7 1.9 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SOG2 PF10428.9 ETS75660.1 - 0.99 8.5 19.8 1.1 8.4 19.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 ETS75660.1 - 1.9 7.0 14.6 2.2 6.7 14.6 1.0 1 0 0 1 1 1 0 Macoilin family SDA1 PF05285.12 ETS75660.1 - 2.6 7.4 9.2 3.4 7.0 9.2 1.2 1 0 0 1 1 1 0 SDA1 DUF572 PF04502.13 ETS75660.1 - 2.6 7.6 6.7 3.2 7.3 6.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Zn_clus PF00172.18 ETS75661.1 - 3.9e-05 23.7 11.6 7.2e-05 22.8 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spidroin_N PF16763.5 ETS75661.1 - 0.055 13.5 0.4 0.13 12.3 0.4 1.5 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term CDK2AP PF09806.9 ETS75661.1 - 0.15 12.1 5.4 0.14 12.2 0.2 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF3138 PF11336.8 ETS75661.1 - 0.86 8.1 2.9 1.5 7.4 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CorA PF01544.18 ETS75662.1 - 2.4e-38 132.1 0.1 3.5e-38 131.6 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Cytidylate_kin PF02224.18 ETS75662.1 - 0.13 11.9 0.2 0.25 11.0 0.2 1.4 1 0 0 1 1 1 0 Cytidylate kinase SPC12 PF06645.13 ETS75664.1 - 2.4e-31 107.6 0.3 2.9e-31 107.4 0.3 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) zf-rbx1 PF12678.7 ETS75665.1 - 6.9e-25 87.1 12.9 9.5e-25 86.7 12.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ETS75665.1 - 4.6e-17 61.9 9.8 6e-17 61.5 9.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 ETS75665.1 - 4.1e-06 27.0 14.3 0.00015 22.0 14.3 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ETS75665.1 - 5.2e-05 23.0 3.1 5.2e-05 23.0 3.1 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ETS75665.1 - 0.0016 18.3 11.5 0.028 14.3 11.5 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS75665.1 - 0.21 11.5 10.9 0.65 9.9 4.6 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ETS75665.1 - 0.33 10.7 15.9 28 4.6 15.9 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 ETS75665.1 - 0.39 10.8 6.8 1.4 9.0 6.8 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 ETS75665.1 - 1 9.6 9.3 5.6 7.2 9.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 ETS75665.1 - 1.4 8.6 15.1 2.1e+02 1.6 15.1 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 ETS75665.1 - 7.4 6.6 12.5 65 3.6 12.5 2.5 1 1 0 1 1 1 0 zinc-RING finger domain PNRC PF15365.6 ETS75666.1 - 5.8e-07 29.2 8.2 5.8e-07 29.2 8.2 4.4 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif MBF1 PF08523.10 ETS75666.1 - 0.17 12.3 0.2 0.17 12.3 0.2 2.9 3 0 0 3 3 3 0 Multiprotein bridging factor 1 p450 PF00067.22 ETS75667.1 - 2.9e-45 154.9 0.0 3.8e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tyr-DNA_phospho PF06087.12 ETS75668.1 - 1.1e-86 291.4 0.0 2.3e-86 290.3 0.0 1.5 2 0 0 2 2 2 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 ETS75668.1 - 3.4e-05 23.5 1.7 0.0087 15.9 0.2 3.9 5 0 0 5 5 5 2 Ubiquitin interaction motif PLDc_2 PF13091.6 ETS75668.1 - 0.0004 20.3 0.0 0.0042 17.0 0.0 2.3 2 0 0 2 2 2 1 PLD-like domain Gti1_Pac2 PF09729.9 ETS75669.1 - 1.1e-61 208.1 1.3 1.8e-61 207.4 0.0 1.8 2 0 0 2 2 2 1 Gti1/Pac2 family CDP-OH_P_transf PF01066.21 ETS75670.1 - 4.3e-14 53.0 0.5 4.3e-14 53.0 0.5 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GIDA PF01134.22 ETS75671.1 - 9.5e-159 528.7 0.0 1.2e-158 528.4 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 ETS75671.1 - 7.9e-69 232.0 0.0 1.1e-68 231.5 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 ETS75671.1 - 1.3e-06 28.0 0.3 2.3e-06 27.3 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS75671.1 - 3.5e-05 23.2 0.8 6.7e-05 22.3 0.8 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS75671.1 - 0.0012 18.0 1.8 0.0012 18.0 1.8 2.4 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 ETS75671.1 - 0.0061 15.9 0.2 0.013 14.8 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ETS75671.1 - 0.026 13.3 0.9 0.16 10.6 0.4 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.6 ETS75671.1 - 0.17 12.3 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Sec1 PF00995.23 ETS75672.1 - 4.7e-135 452.1 0.0 5.5e-135 451.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family B12-binding PF02310.19 ETS75672.1 - 0.29 11.2 1.2 0.74 9.9 0.1 2.2 2 1 0 2 2 2 0 B12 binding domain MMM1 PF10296.9 ETS75673.1 - 2.5e-140 467.3 0.0 7.7e-139 462.4 0.0 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Importin_rep_3 PF18806.1 ETS75674.1 - 0.00012 22.0 0.1 0.0019 18.2 0.0 3.0 3 0 0 3 3 3 1 Importin 13 repeat Creatinase_N_2 PF16189.5 ETS75675.1 - 1.2e-54 184.8 0.5 5.8e-53 179.3 0.1 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 ETS75675.1 - 5.4e-46 156.9 0.1 7.6e-46 156.4 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 ETS75675.1 - 1.2e-22 80.9 0.1 3.6e-18 66.5 0.0 2.6 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 ETS75675.1 - 1.9e-21 75.9 0.2 5.5e-21 74.4 0.2 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 FUN14 PF04930.15 ETS75676.1 - 0.00021 21.7 4.3 0.00021 21.7 4.3 2.1 2 1 0 2 2 2 1 FUN14 family Histone PF00125.24 ETS75677.1 - 4.2e-42 143.6 0.1 4.3e-42 143.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ETS75677.1 - 1.3e-05 25.3 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 ETS75677.1 - 0.00015 22.1 0.1 0.0002 21.6 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 ETS75677.1 - 0.0065 16.7 0.1 0.01 16.1 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ETS75677.1 - 0.11 12.5 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DER1 PF04511.15 ETS75678.1 - 7.3e-49 166.3 5.2 8.4e-49 166.1 5.2 1.0 1 0 0 1 1 1 1 Der1-like family ARD PF03079.14 ETS75679.1 - 6.3e-47 159.7 0.3 7.5e-47 159.4 0.3 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 ETS75679.1 - 9.4e-09 34.9 0.1 1.5e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 ETS75679.1 - 6.8e-06 26.0 0.0 9.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 ETS75679.1 - 0.062 12.9 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 Cupin SH3_16 PF18348.1 ETS75679.1 - 0.067 13.0 0.3 0.14 11.9 0.3 1.6 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain adh_short PF00106.25 ETS75680.1 - 6e-33 113.9 0.0 9.6e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS75680.1 - 5.9e-22 78.4 0.0 1.1e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS75680.1 - 3.6e-11 43.3 0.0 5.6e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS75680.1 - 1.5e-06 27.9 0.0 2.9e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ETS75680.1 - 0.00029 20.1 0.0 0.00039 19.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ETS75680.1 - 0.001 19.0 0.0 0.0016 18.4 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ETS75680.1 - 0.0011 18.2 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ETS75680.1 - 0.0032 16.5 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ETS75680.1 - 0.0088 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ETS75680.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family DapB_N PF01113.20 ETS75680.1 - 0.057 13.6 0.0 0.098 12.8 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus EamA PF00892.20 ETS75681.1 - 0.0053 16.9 30.0 0.0097 16.1 9.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family MBOAT PF03062.19 ETS75682.1 - 2.1e-58 198.3 6.9 4.2e-58 197.4 6.9 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PAP2 PF01569.21 ETS75682.1 - 0.017 14.9 3.6 0.058 13.2 3.6 1.9 1 0 0 1 1 1 0 PAP2 superfamily CPBP PF02517.16 ETS75684.1 - 9.3e-14 51.6 12.8 9.3e-14 51.6 12.8 2.5 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease tRNA-synt_1b PF00579.25 ETS75685.1 - 5.7e-72 242.5 0.0 7.2e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) LktC PF06261.11 ETS75685.1 - 0.25 11.3 0.0 0.45 10.4 0.0 1.4 1 0 0 1 1 1 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC Ribosomal_S10 PF00338.22 ETS75686.1 - 2.4e-25 88.6 0.0 4e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e JAB PF01398.21 ETS75687.1 - 7.1e-32 109.9 0.1 1.2e-31 109.1 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 ETS75687.1 - 1.4e-21 77.2 0.2 3.3e-21 76.0 0.2 1.7 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 ETS75687.1 - 6.8e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 ETS75687.1 - 0.12 12.5 0.0 0.28 11.2 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) HoxA13_N PF12284.8 ETS75687.1 - 0.12 13.0 0.3 0.25 12.0 0.1 1.6 2 0 0 2 2 2 0 Hox protein A13 N terminal tRNA-synt_1c PF00749.21 ETS75688.1 - 2.7e-93 312.3 0.0 3.7e-93 311.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ_C PF01556.18 ETS75689.1 - 2.6e-37 128.2 0.1 3.6e-37 127.7 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ETS75689.1 - 1.6e-24 85.8 2.8 1.6e-24 85.8 2.8 1.7 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ETS75689.1 - 1.6e-14 54.0 18.8 2.6e-14 53.3 18.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Val_tRNA-synt_C PF10458.9 ETS75689.1 - 0.047 14.0 0.9 0.11 12.8 0.9 1.5 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Cupin_2 PF07883.11 ETS75689.1 - 0.18 11.5 0.2 0.53 10.0 0.0 1.8 2 0 0 2 2 2 0 Cupin domain DZR PF12773.7 ETS75689.1 - 0.28 11.2 9.3 0.82 9.8 1.4 2.3 2 0 0 2 2 2 0 Double zinc ribbon HypA PF01155.19 ETS75689.1 - 0.46 10.5 7.4 4.7 7.3 1.1 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 ETS75689.1 - 0.82 9.7 16.8 0.55 10.2 3.1 2.7 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 ETS75689.1 - 9.1 5.9 8.3 15 5.2 1.7 2.1 1 1 0 2 2 2 0 Thaumarchaeal output domain 1 Ribosomal_L32e PF01655.18 ETS75690.1 - 5.1e-51 171.6 1.4 5.1e-51 171.6 1.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L32 Pectate_lyase PF03211.13 ETS75691.1 - 5e-86 287.4 5.0 6e-86 287.2 5.0 1.1 1 0 0 1 1 1 1 Pectate lyase Pyr_redox_2 PF07992.14 ETS75692.1 - 2.7e-44 151.6 0.0 6.5e-39 133.9 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS75692.1 - 2e-12 47.5 0.0 1.8e-10 41.3 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS75692.1 - 0.00012 21.5 0.1 0.15 11.3 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS75692.1 - 0.026 14.1 0.8 1.8 8.0 0.0 3.3 2 1 0 4 4 4 0 FAD dependent oxidoreductase Peptidase_M16_C PF05193.21 ETS75693.1 - 1.2e-55 188.4 0.0 2.2e-55 187.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ETS75693.1 - 7.7e-42 142.8 0.0 5.8e-41 139.9 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Tannase PF07519.11 ETS75696.1 - 1e-133 446.7 2.6 1.2e-133 446.5 2.6 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_C25_C PF03785.14 ETS75696.1 - 0.09 12.6 0.3 15 5.5 0.7 2.6 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain Egh16-like PF11327.8 ETS75697.1 - 5.5e-16 59.5 13.8 5.5e-16 59.5 13.8 1.8 2 1 0 2 2 2 1 Egh16-like virulence factor TPR_12 PF13424.6 ETS75698.1 - 5.7e-29 100.2 19.1 6.3e-11 42.4 0.1 5.9 3 1 3 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 ETS75698.1 - 5.6e-26 89.6 24.0 0.00027 20.7 0.0 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 ETS75698.1 - 3e-21 73.8 0.1 0.0075 16.4 0.0 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 ETS75698.1 - 3.6e-20 70.4 11.5 0.1 12.7 0.0 9.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 ETS75698.1 - 2.1e-15 55.5 7.9 1.1 9.5 0.0 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 ETS75698.1 - 6.3e-14 52.2 16.8 0.00038 20.9 0.2 7.6 2 1 6 8 8 8 6 Tetratricopeptide repeat NB-ARC PF00931.22 ETS75698.1 - 2.8e-12 46.4 0.0 4.5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain ANAPC3 PF12895.7 ETS75698.1 - 3.2e-11 43.3 10.8 0.035 14.3 0.0 7.5 2 1 5 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 ETS75698.1 - 1e-10 41.0 0.3 3.7 7.5 0.0 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 ETS75698.1 - 2.4e-10 40.3 22.1 0.95 10.5 0.2 8.8 7 2 2 9 9 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 ETS75698.1 - 7.6e-09 35.6 5.6 0.63 10.8 0.0 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat PPR PF01535.20 ETS75698.1 - 7.9e-09 35.2 1.8 8.1 6.9 0.0 7.1 7 0 0 7 7 6 0 PPR repeat TPR_16 PF13432.6 ETS75698.1 - 3.4e-06 27.6 15.0 6.3 7.5 0.1 8.1 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.6 ETS75698.1 - 3.3e-05 24.1 18.6 0.78 10.1 0.3 6.4 1 1 6 7 7 7 3 Tetratricopeptide repeat PPR_1 PF12854.7 ETS75698.1 - 6.3e-05 22.6 0.1 19 5.1 0.0 5.0 5 0 0 5 5 5 0 PPR repeat TPR_4 PF07721.14 ETS75698.1 - 7.6e-05 23.0 8.0 0.6 10.9 0.4 6.4 6 0 0 6 6 4 1 Tetratricopeptide repeat NACHT PF05729.12 ETS75698.1 - 0.00063 19.7 0.1 0.0015 18.5 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ETS75698.1 - 0.00071 19.9 0.0 0.0021 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain Paf67 PF10255.9 ETS75698.1 - 0.0013 17.8 2.0 0.37 9.7 0.0 4.0 2 1 2 5 5 5 1 RNA polymerase I-associated factor PAF67 PPR_2 PF13041.6 ETS75698.1 - 0.0033 17.6 0.0 54 4.1 0.0 5.3 6 0 0 6 6 6 0 PPR repeat family AAA_16 PF13191.6 ETS75698.1 - 0.0091 16.4 0.4 0.0091 16.4 0.4 3.2 2 2 0 2 2 2 1 AAA ATPase domain PNP_UDP_1 PF01048.20 ETS75698.1 - 0.0094 15.2 0.0 0.024 13.9 0.0 1.7 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4248 PF14053.6 ETS75698.1 - 0.022 14.8 1.3 4 7.5 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4248) TniB PF05621.11 ETS75698.1 - 0.051 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein YfdX PF10938.8 ETS75698.1 - 0.088 12.7 7.0 0.38 10.7 0.5 3.9 4 1 0 4 4 4 0 YfdX protein TPR_17 PF13431.6 ETS75698.1 - 0.74 10.3 11.2 93 3.8 0.0 6.0 7 0 0 7 7 5 0 Tetratricopeptide repeat Fic PF02661.18 ETS75699.1 - 1.3e-20 74.1 0.0 3.4e-20 72.7 0.0 1.8 2 0 0 2 2 2 1 Fic/DOC family Img2 PF05046.14 ETS75699.1 - 0.071 13.4 0.0 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) WD40 PF00400.32 ETS75700.1 - 1.1e-37 127.4 27.1 4.7e-08 33.6 0.3 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS75700.1 - 1.4e-12 47.7 4.2 0.086 13.2 0.0 5.5 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 ETS75700.1 - 1.6e-11 43.9 2.0 3.6e-11 42.8 2.0 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 ETS75700.1 - 2.3e-07 29.9 8.5 0.068 11.8 0.2 6.0 2 1 5 7 7 7 3 Nucleoporin Nup120/160 F-box PF00646.33 ETS75700.1 - 9.8e-06 25.3 3.2 2.2e-05 24.2 3.2 1.6 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 ETS75700.1 - 0.00016 21.1 0.0 0.016 14.6 0.0 2.4 1 1 1 2 2 2 2 WD40-like domain PQQ_2 PF13360.6 ETS75700.1 - 0.00016 21.3 8.6 0.0016 18.0 2.1 2.4 1 1 1 2 2 2 2 PQQ-like domain BBS2_Mid PF14783.6 ETS75700.1 - 0.00085 19.3 0.0 2.8 8.0 0.0 3.5 3 2 2 5 5 5 2 Ciliary BBSome complex subunit 2, middle region PALB2_WD40 PF16756.5 ETS75700.1 - 0.096 11.6 1.5 15 4.4 0.0 3.4 2 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain PQQ_3 PF13570.6 ETS75700.1 - 0.11 13.0 9.6 5.8 7.5 0.0 5.8 6 0 0 6 6 6 0 PQQ-like domain PQQ PF01011.21 ETS75700.1 - 0.26 11.3 2.1 29 4.8 0.0 4.4 5 0 0 5 5 5 0 PQQ enzyme repeat Zip PF02535.22 ETS75701.1 - 2.5e-37 128.9 2.2 2.2e-25 89.6 5.8 2.6 1 1 1 2 2 2 2 ZIP Zinc transporter Hat1_N PF10394.9 ETS75702.1 - 2.5e-52 177.3 0.0 5e-52 176.4 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 ETS75702.1 - 0.015 15.5 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS75702.1 - 0.061 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DEP PF00610.21 ETS75702.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) P5CR_dimer PF14748.6 ETS75703.1 - 1.6e-33 115.0 3.7 2.8e-33 114.3 3.7 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 ETS75703.1 - 5.3e-13 49.4 3.0 2.4e-10 40.9 0.1 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent DUF1449 PF07290.11 ETS75703.1 - 0.036 13.7 1.0 0.05 13.2 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) PDH PF02153.17 ETS75703.1 - 0.04 12.9 1.4 0.065 12.2 1.4 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase CTK3 PF12243.8 ETS75704.1 - 1.4e-45 154.2 0.0 2.4e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 ETS75704.1 - 3.7e-17 62.2 12.9 1.1e-16 60.7 12.9 1.9 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus DUF1759 PF03564.15 ETS75704.1 - 0.75 9.7 3.2 0.94 9.4 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) Ribosomal_L12 PF00542.19 ETS75705.1 - 1.6e-21 76.4 6.2 1.4e-20 73.4 4.5 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 ETS75705.1 - 3.7e-13 49.0 6.8 3.7e-13 49.0 6.8 2.3 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 ETS75705.1 - 0.019 15.6 3.7 0.019 15.6 3.7 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein AAA_5 PF07728.14 ETS75706.1 - 1.5e-127 420.2 0.0 1.2e-20 74.0 0.0 9.6 8 1 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 ETS75706.1 - 2e-61 204.8 0.8 2e-26 92.3 0.0 6.3 6 0 0 6 6 6 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 ETS75706.1 - 2.8e-33 114.2 0.1 1.5e-31 108.6 0.0 3.0 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_3 PF07726.11 ETS75706.1 - 1.7e-30 105.6 0.0 6.6e-11 42.2 0.0 6.9 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS75706.1 - 1.8e-28 100.0 27.8 1e-05 26.0 0.6 9.8 8 2 0 8 8 6 6 AAA ATPase domain AAA PF00004.29 ETS75706.1 - 2e-28 99.5 0.2 5.9e-05 23.5 0.0 7.7 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ETS75706.1 - 2.8e-28 98.6 2.9 1.9e-05 24.3 0.0 7.2 6 1 0 6 6 6 6 P-loop containing dynein motor region Dynein_heavy PF03028.15 ETS75706.1 - 7.4e-26 90.6 0.0 0.0022 18.1 0.0 8.3 7 1 0 7 7 6 5 Dynein heavy chain region D6 P-loop domain AAA_6 PF12774.7 ETS75706.1 - 2.9e-22 79.1 0.0 0.003 16.6 0.1 8.4 8 0 0 8 8 8 5 Hydrolytic ATP binding site of dynein motor region AAA_33 PF13671.6 ETS75706.1 - 1.1e-21 77.4 0.0 0.0041 17.3 0.0 7.5 6 1 0 6 6 6 5 AAA domain AAA_22 PF13401.6 ETS75706.1 - 8.4e-21 74.7 4.1 0.0033 17.7 0.0 7.7 7 0 0 7 7 6 4 AAA domain AAA_18 PF13238.6 ETS75706.1 - 4e-20 72.7 0.7 0.0075 16.8 0.0 7.6 7 0 0 7 7 6 3 AAA domain Sigma54_activat PF00158.26 ETS75706.1 - 7.7e-20 71.3 0.1 0.033 13.9 0.0 7.0 7 0 0 7 7 7 4 Sigma-54 interaction domain AAA_30 PF13604.6 ETS75706.1 - 2.4e-16 60.0 0.0 0.05 13.3 0.0 8.1 7 2 0 7 7 6 2 AAA domain TsaE PF02367.17 ETS75706.1 - 1.2e-15 57.6 5.8 0.042 13.9 0.2 6.5 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 ETS75706.1 - 8.7e-15 55.1 4.2 0.00049 20.2 0.0 6.8 6 0 0 6 6 6 2 Sigma-54 interaction domain AAA_14 PF13173.6 ETS75706.1 - 9.9e-15 54.7 0.0 0.046 13.8 0.0 7.6 7 0 0 7 7 7 2 AAA domain T2SSE PF00437.20 ETS75706.1 - 4.2e-14 52.3 2.1 0.016 14.3 0.0 6.5 6 0 0 6 6 6 3 Type II/IV secretion system protein RNA_helicase PF00910.22 ETS75706.1 - 2.6e-13 50.3 3.1 0.082 13.3 0.0 7.3 7 0 0 7 7 7 1 RNA helicase RuvB_N PF05496.12 ETS75706.1 - 3.6e-13 49.5 4.8 0.0086 15.8 0.0 6.4 7 0 0 7 7 6 3 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 ETS75706.1 - 4.3e-12 46.3 2.0 0.035 14.0 0.0 6.5 6 0 0 6 6 6 1 Rad17 P-loop domain ABC_tran PF00005.27 ETS75706.1 - 4.5e-12 46.7 13.3 0.016 15.7 0.0 7.9 8 0 0 8 8 6 3 ABC transporter NACHT PF05729.12 ETS75706.1 - 1e-11 45.0 10.6 0.45 10.4 0.1 6.7 7 0 0 7 7 5 4 NACHT domain RsgA_GTPase PF03193.16 ETS75706.1 - 2e-11 44.1 6.9 0.92 9.4 0.1 6.2 6 0 0 6 6 5 3 RsgA GTPase AAA_29 PF13555.6 ETS75706.1 - 8.7e-11 41.4 0.7 0.35 10.6 0.0 6.6 6 0 0 6 6 6 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 ETS75706.1 - 7.8e-10 38.4 4.5 0.22 10.8 0.0 6.9 7 0 0 7 7 6 2 Zeta toxin Mg_chelatase PF01078.21 ETS75706.1 - 3.2e-09 36.5 5.9 2.8 7.3 0.0 8.2 9 0 0 9 9 8 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 ETS75706.1 - 4.7e-09 36.7 6.2 0.46 10.7 0.1 7.2 6 0 0 6 6 6 1 AAA domain AAA_25 PF13481.6 ETS75706.1 - 5e-09 36.0 6.7 1.5 8.3 0.0 5.8 5 0 0 5 5 5 2 AAA domain AAA_19 PF13245.6 ETS75706.1 - 1.6e-08 35.0 5.2 2.9 8.2 0.1 6.4 6 0 0 6 6 5 0 AAA domain IstB_IS21 PF01695.17 ETS75706.1 - 2.3e-08 34.0 0.9 0.16 11.7 0.0 6.0 6 0 0 6 6 6 1 IstB-like ATP binding protein ATPase_2 PF01637.18 ETS75706.1 - 3.4e-08 33.7 0.0 0.63 9.9 0.0 6.4 6 0 0 6 6 6 1 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 ETS75706.1 - 1.8e-07 31.2 5.4 1.9 8.4 0.1 6.4 6 0 0 6 6 6 2 NTPase PduV-EutP PF10662.9 ETS75706.1 - 2.5e-07 30.5 0.9 0.075 12.8 0.0 6.1 7 0 0 7 7 6 1 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.18 ETS75706.1 - 1e-06 28.7 0.1 0.37 10.5 0.0 5.5 6 0 0 6 6 5 1 Viral (Superfamily 1) RNA helicase dNK PF01712.19 ETS75706.1 - 1.2e-06 28.6 1.6 3.9 7.3 0.0 5.6 5 0 0 5 5 5 0 Deoxynucleoside kinase SRP54 PF00448.22 ETS75706.1 - 1.4e-06 28.1 5.0 1.2 8.7 0.1 5.2 5 0 0 5 5 4 2 SRP54-type protein, GTPase domain AAA_24 PF13479.6 ETS75706.1 - 2.2e-06 27.5 0.2 4.7 6.9 0.0 6.2 6 0 0 6 6 5 0 AAA domain TniB PF05621.11 ETS75706.1 - 2.8e-06 26.9 0.3 5 6.5 0.0 5.9 6 0 0 6 6 6 0 Bacterial TniB protein AAA_17 PF13207.6 ETS75706.1 - 9.6e-06 26.1 5.9 2 8.8 0.0 6.1 5 0 0 5 5 5 1 AAA domain TIP49 PF06068.13 ETS75706.1 - 1.6e-05 24.3 1.3 4.6 6.3 0.0 5.1 6 0 0 6 6 6 0 TIP49 P-loop domain Thymidylate_kin PF02223.17 ETS75706.1 - 2e-05 24.3 0.1 2.8 7.6 0.0 5.8 5 0 0 5 5 5 0 Thymidylate kinase DUF815 PF05673.13 ETS75706.1 - 2.1e-05 23.8 4.7 2.8 7.0 0.0 5.8 6 0 0 6 6 6 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 ETS75706.1 - 3.3e-05 23.9 2.1 17 5.5 0.0 6.3 6 0 0 6 6 6 0 50S ribosome-binding GTPase ResIII PF04851.15 ETS75706.1 - 3.6e-05 23.8 0.1 2.4 8.1 0.0 5.5 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit CbiA PF01656.23 ETS75706.1 - 9.3e-05 22.5 0.4 14 5.7 0.0 5.8 6 0 0 6 6 5 0 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 ETS75706.1 - 9.9e-05 21.9 0.0 0.62 9.5 0.0 4.6 5 0 0 5 5 4 1 Chromatin associated protein KTI12 cobW PF02492.19 ETS75706.1 - 0.00012 21.7 6.2 9 5.8 0.0 5.9 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 ETS75706.1 - 0.00016 21.1 0.0 7.4 5.7 0.0 5.1 6 0 0 6 6 4 0 KAP family P-loop domain Roc PF08477.13 ETS75706.1 - 0.00082 19.6 2.2 33 4.7 0.1 5.9 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 ETS75706.1 - 0.0014 18.5 8.9 9 6.0 0.1 6.4 7 0 0 7 7 6 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 ETS75706.1 - 0.0017 17.8 2.1 14 5.1 0.0 5.5 6 0 0 6 6 5 0 Signal recognition particle receptor beta subunit SKI PF01202.22 ETS75706.1 - 0.0017 18.5 0.9 9 6.4 0.0 4.6 4 0 0 4 4 4 0 Shikimate kinase AAA_8 PF12780.7 ETS75706.1 - 0.0019 17.6 0.8 54 3.0 0.0 5.7 6 0 0 6 6 6 0 P-loop containing dynein motor region D4 CPT PF07931.12 ETS75706.1 - 0.0025 17.7 1.6 31 4.4 0.0 5.9 5 1 0 5 5 4 0 Chloramphenicol phosphotransferase-like protein GAF_2 PF13185.6 ETS75706.1 - 0.01 16.2 0.0 0.11 12.8 0.0 2.8 2 0 0 2 2 2 1 GAF domain DEAD PF00270.29 ETS75706.1 - 0.011 15.6 0.1 17 5.1 0.0 4.7 5 0 0 5 5 4 0 DEAD/DEAH box helicase DAP3 PF10236.9 ETS75706.1 - 0.011 14.9 7.5 8.9 5.4 0.0 4.9 5 0 0 5 5 5 0 Mitochondrial ribosomal death-associated protein 3 ATPase PF06745.13 ETS75706.1 - 0.039 13.3 0.1 23 4.2 0.0 4.6 5 0 0 5 5 4 0 KaiC PhoH PF02562.16 ETS75706.1 - 0.041 13.3 0.3 8.7 5.7 0.0 3.9 4 0 0 4 4 3 0 PhoH-like protein VWA_2 PF13519.6 ETS75706.1 - 0.096 13.3 0.2 0.69 10.6 0.0 2.7 2 0 0 2 2 1 0 von Willebrand factor type A domain APS_kinase PF01583.20 ETS75706.1 - 0.11 12.4 1.5 11 5.8 0.0 4.2 5 0 0 5 5 3 0 Adenylylsulphate kinase MeaB PF03308.16 ETS75706.1 - 0.12 11.3 2.3 16 4.4 0.0 3.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 ETS75706.1 - 0.41 10.3 5.2 14 5.3 0.0 4.6 6 0 0 6 6 3 0 Phosphoribulokinase / Uridine kinase family NMO PF03060.15 ETS75707.1 - 7.5e-36 124.2 5.1 1.6e-29 103.3 4.4 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 ETS75707.1 - 9e-10 38.1 5.2 1.3e-09 37.5 5.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ETS75707.1 - 2.2e-08 33.5 7.4 1.8e-06 27.2 7.3 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ETS75707.1 - 1.6e-05 24.3 3.6 2.6e-05 23.5 3.6 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Clr5 PF14420.6 ETS75708.1 - 4.1e-15 55.7 0.1 4.1e-15 55.7 0.1 2.2 3 0 0 3 3 3 1 Clr5 domain zf-RING_2 PF13639.6 ETS75710.1 - 6e-08 32.9 0.3 6e-08 32.9 0.3 3.7 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 ETS75710.1 - 1.4e-07 31.6 9.4 6.3e-06 26.4 0.3 3.3 3 0 0 3 3 3 2 RING-H2 zinc finger domain PHD PF00628.29 ETS75710.1 - 5.2e-07 29.4 11.2 5.2e-07 29.4 11.2 2.8 2 0 0 2 2 2 1 PHD-finger Prok-RING_4 PF14447.6 ETS75710.1 - 3.1e-05 23.8 0.9 3.1e-05 23.8 0.9 3.4 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 ETS75710.1 - 0.00018 21.3 0.1 0.00018 21.3 0.1 3.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ETS75710.1 - 0.00034 20.5 1.4 0.00034 20.5 1.4 3.7 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ETS75710.1 - 0.00038 20.2 0.8 0.00038 20.2 0.8 3.5 3 1 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 ETS75710.1 - 0.00071 19.1 1.1 0.00071 19.1 1.1 2.6 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 ETS75710.1 - 0.0012 18.9 0.2 0.0012 18.9 0.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 ETS75710.1 - 0.0031 17.3 0.3 0.0031 17.3 0.3 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 ETS75710.1 - 0.056 12.8 0.1 0.056 12.8 0.1 3.4 2 1 0 3 3 3 0 Rtf2 RING-finger Remorin_N PF03766.13 ETS75710.1 - 0.064 13.3 0.4 0.2 11.7 0.4 1.9 1 0 0 1 1 1 0 Remorin, N-terminal region Ribosomal_L37ae PF01780.19 ETS75711.1 - 3e-41 139.4 9.5 3.4e-41 139.2 9.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 ETS75711.1 - 0.002 18.2 1.4 0.0029 17.7 1.4 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-H2C2_2 PF13465.6 ETS75711.1 - 0.015 15.7 0.6 2.6 8.6 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 ETS75711.1 - 0.041 13.9 2.8 0.072 13.1 2.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.15 ETS75711.1 - 0.71 10.0 6.4 3.4 7.7 0.9 2.2 1 1 1 2 2 2 0 BED zinc finger Sacchrp_dh_NADP PF03435.18 ETS75712.1 - 3.8e-16 59.5 0.1 5.8e-16 58.9 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 ETS75712.1 - 0.013 15.9 0.0 0.03 14.8 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF155 PF02582.14 ETS75713.1 - 8.7e-51 172.5 0.3 1.3e-50 172.0 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 HMG_box PF00505.19 ETS75714.1 - 1.7e-09 38.0 1.5 4.5e-09 36.6 1.5 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ETS75714.1 - 0.0033 18.0 4.2 0.0074 16.9 3.4 2.0 1 1 0 1 1 1 1 HMG-box domain bZIP_1 PF00170.21 ETS75714.1 - 0.031 14.4 2.4 0.031 14.4 2.4 1.8 2 0 0 2 2 2 0 bZIP transcription factor KfrA_N PF11740.8 ETS75714.1 - 0.066 13.9 6.9 3.6 8.3 0.2 2.5 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Lant_dehydr_C PF14028.6 ETS75714.1 - 0.1 12.2 2.9 0.056 13.0 0.7 1.7 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term DUF3987 PF13148.6 ETS75714.1 - 0.1 11.6 5.6 1.8 7.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF4407 PF14362.6 ETS75714.1 - 1.6 8.0 14.7 7.1 5.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cpn60_TCP1 PF00118.24 ETS75715.1 - 3.8e-152 507.3 8.7 4.3e-152 507.2 8.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAL PF00563.20 ETS75715.1 - 0.0032 17.0 0.2 0.0088 15.6 0.0 1.7 2 0 0 2 2 2 1 EAL domain DUF2204 PF09970.9 ETS75715.1 - 0.01 15.5 0.1 4.4 6.9 0.0 3.2 3 0 0 3 3 3 0 Nucleotidyl transferase of unknown function (DUF2204) Nitro_FeMo-Co PF02579.17 ETS75715.1 - 0.087 13.2 0.1 0.43 10.9 0.0 2.3 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Adhesin_P1_N PF18652.1 ETS75715.1 - 0.55 10.3 4.6 28 4.8 0.1 3.5 3 0 0 3 3 3 0 Adhesin P1 N-terminal domain HET PF06985.11 ETS75716.1 - 1.8e-28 99.7 0.2 4e-28 98.6 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ETS75717.1 - 1.3e-13 51.6 6.6 9.7e-11 42.2 7.0 3.5 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ETS75718.1 - 2.1e-35 122.2 1.7 5.5e-35 120.9 1.1 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 ETS75719.1 - 3.3e-52 177.8 0.0 4.2e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 KR PF08659.10 ETS75720.1 - 7.7e-56 188.8 0.2 1.3e-55 188.1 0.2 1.4 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.6 ETS75720.1 - 3.8e-16 60.3 0.0 6.9e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ETS75720.1 - 2e-11 44.0 0.0 4.5e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ETS75720.1 - 3.5e-11 42.9 0.0 7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 ETS75720.1 - 7.5e-11 42.2 0.3 2.5e-10 40.6 0.1 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 ETS75720.1 - 7.4e-06 25.7 0.3 0.00024 20.8 0.0 2.6 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 ETS75720.1 - 0.087 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain HET PF06985.11 ETS75722.1 - 1.3e-31 109.9 0.1 5.2e-31 108.0 0.1 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PH_10 PF15411.6 ETS75724.1 - 1.2e-29 103.1 0.1 2e-29 102.3 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 ETS75724.1 - 4.3e-15 56.4 0.0 7.4e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 ETS75724.1 - 2.8e-10 40.4 0.0 1.3e-09 38.2 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 ETS75724.1 - 0.00018 21.8 5.2 0.0003 21.0 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 ETS75724.1 - 0.0019 17.8 2.4 0.0041 16.7 2.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 ETS75724.1 - 0.0032 17.4 5.4 0.0054 16.7 5.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ETS75724.1 - 0.013 15.3 3.9 0.024 14.5 3.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ETS75724.1 - 0.02 14.7 4.5 0.038 13.9 4.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ETS75724.1 - 0.022 15.0 2.4 0.048 14.0 2.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Phage_tail_APC PF16778.5 ETS75724.1 - 0.067 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Phage tail assembly chaperone protein zf-RING-like PF08746.11 ETS75724.1 - 0.073 13.4 3.9 0.13 12.6 3.9 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_11 PF17123.5 ETS75724.1 - 0.12 12.2 3.6 0.25 11.1 3.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger NAD_synthase PF02540.17 ETS75724.1 - 0.14 11.3 0.1 1 8.4 0.0 2.0 2 0 0 2 2 2 0 NAD synthase Prok-RING_1 PF14446.6 ETS75724.1 - 2 8.4 4.3 7.9 6.5 0.5 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3H2C3 PF17122.5 ETS75724.1 - 3.9 7.6 4.7 8.1 6.6 4.7 1.6 1 0 0 1 1 1 0 Zinc-finger zf-RING_UBOX PF13445.6 ETS75724.1 - 4.5 7.4 5.4 12 6.0 5.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger 2OG-FeII_Oxy PF03171.20 ETS75725.1 - 4.9e-09 36.6 0.0 8.4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ETS75725.1 - 2.9e-08 34.5 0.0 6.1e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Ribosomal_L27A PF00828.19 ETS75726.1 - 2.2e-34 118.9 0.8 3.2e-34 118.4 0.8 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A WSC PF01822.19 ETS75729.1 - 7.1e-11 42.2 9.3 7.1e-11 42.2 9.3 2.3 2 0 0 2 2 2 1 WSC domain SprA-related PF12118.8 ETS75729.1 - 0.26 10.4 10.9 0.29 10.2 10.9 1.2 1 0 0 1 1 1 0 SprA-related family Sporozoite_P67 PF05642.11 ETS75729.1 - 6.7 4.7 13.3 7 4.6 13.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sel1 PF08238.12 ETS75730.1 - 0.052 14.3 0.2 0.23 12.2 0.1 2.2 2 0 0 2 2 2 0 Sel1 repeat TPR_12 PF13424.6 ETS75730.1 - 0.097 13.0 0.1 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4432 PF14486.6 ETS75730.1 - 0.18 10.6 0.0 0.32 9.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) U3_snoRNA_assoc PF08297.11 ETS75731.1 - 4.5e-12 46.5 0.6 4.5e-12 46.5 0.6 5.1 2 1 2 4 4 4 1 U3 snoRNA associated FAD_binding_3 PF01494.19 ETS75732.1 - 8.9e-19 67.9 0.6 2.2e-09 37.0 0.5 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS75732.1 - 6.3e-06 26.3 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS75732.1 - 0.0015 17.9 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS75732.1 - 0.0078 15.5 0.1 0.064 12.5 0.0 2.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS75732.1 - 0.055 14.0 0.1 1.2 9.8 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_3_C PF01915.22 ETS75733.1 - 1.3e-47 162.4 0.0 2.5e-47 161.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ETS75733.1 - 1.2e-25 89.3 0.0 2.2e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 ETS75733.1 - 2.5e-19 69.8 0.0 4.9e-19 68.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PX PF00787.24 ETS75734.1 - 3.1e-17 62.6 0.0 6.4e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 PX domain Cullin_binding PF03556.15 ETS75735.1 - 1.7e-31 109.2 2.6 3e-31 108.4 2.6 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 ETS75735.1 - 1.5e-07 31.1 0.0 3.4e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 UBA-like domain Ribosomal_S6 PF01250.17 ETS75736.1 - 2.2e-22 79.1 0.0 2.6e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S6 COX5B PF01215.19 ETS75738.1 - 2.2e-56 189.1 0.1 2.7e-56 188.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.19 ETS75738.1 - 0.025 14.4 0.5 7.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger A2L_zn_ribbon PF08792.10 ETS75738.1 - 0.16 11.7 0.0 0.4 10.5 0.0 1.6 2 0 0 2 2 2 0 A2L zinc ribbon domain NUDIX PF00293.28 ETS75739.1 - 6.4e-19 68.3 0.1 9.1e-19 67.8 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 ETS75739.1 - 0.0043 17.0 0.1 0.011 15.7 0.1 1.8 1 1 0 1 1 1 1 NUDIX domain Asp PF00026.23 ETS75740.1 - 1.7e-56 192.0 2.2 2.2e-56 191.6 2.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS75740.1 - 4.1e-13 49.9 1.4 4.1e-13 49.9 1.4 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 ETS75740.1 - 0.019 15.5 0.1 0.42 11.2 0.0 3.2 5 0 0 5 5 5 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 ETS75740.1 - 0.69 10.6 5.0 1.8 9.3 0.1 3.7 5 0 0 5 5 5 0 Aspartyl protease NAD_binding_1 PF00175.21 ETS75741.1 - 7.3e-14 52.3 0.0 1.6e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 ETS75741.1 - 1.1e-09 38.9 0.1 3.8e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.24 ETS75741.1 - 2.5e-05 24.6 0.0 0.14 12.5 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ETS75741.1 - 0.00019 21.6 0.2 0.0075 16.4 0.1 3.0 2 1 1 3 3 3 1 Ferric reductase NAD binding domain Protoglobin PF11563.8 ETS75741.1 - 0.0023 17.9 0.1 0.0039 17.1 0.1 1.4 1 0 0 1 1 1 1 Protoglobin NmrA PF05368.13 ETS75742.1 - 3.5e-20 72.6 0.0 4.5e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS75742.1 - 1.3e-17 64.2 0.0 2.4e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ETS75742.1 - 3e-05 24.3 0.0 5.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 ETS75742.1 - 0.043 14.2 0.0 0.13 12.7 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain MIP PF00230.20 ETS75744.1 - 3.2e-50 171.0 15.4 3.9e-50 170.7 15.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Menin PF05053.13 ETS75744.1 - 0.51 8.6 1.2 0.69 8.2 1.2 1.1 1 0 0 1 1 1 0 Menin SMP_LBD PF17047.5 ETS75746.1 - 4.2e-24 85.0 0.3 5.8e-24 84.5 0.3 1.2 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 ETS75746.1 - 3.2e-18 65.9 0.0 2.1e-12 47.3 0.0 2.5 2 0 0 2 2 2 2 C2 domain Glyco_hydro_16 PF00722.21 ETS75749.1 - 1.5e-45 154.8 3.6 2.9e-45 153.9 3.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WAP PF00095.21 ETS75749.1 - 1.3 9.5 11.8 0.12 12.8 4.9 2.3 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Chitin_bind_1 PF00187.19 ETS75749.1 - 2.7 8.5 19.0 0.059 13.9 11.6 2.1 2 0 0 2 2 2 0 Chitin recognition protein NAD_binding_10 PF13460.6 ETS75750.1 - 2.7e-16 60.0 0.0 3.5e-14 53.1 0.0 2.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS75750.1 - 0.029 13.9 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family MMR_HSR1 PF01926.23 ETS75751.1 - 4.3e-08 33.2 0.0 1.1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 ETS75751.1 - 8.7e-06 25.2 2.5 4.8e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 AIG1 family FeoB_N PF02421.18 ETS75751.1 - 0.0042 16.6 0.0 0.024 14.2 0.0 2.0 1 1 1 2 2 2 1 Ferrous iron transport protein B IIGP PF05049.13 ETS75751.1 - 0.0052 15.9 1.1 0.0054 15.8 0.0 1.5 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 ETS75751.1 - 0.015 15.2 0.3 0.015 15.2 0.3 2.6 2 2 1 3 3 3 0 RsgA GTPase AAA_29 PF13555.6 ETS75751.1 - 0.017 14.8 0.5 0.039 13.7 0.5 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 ETS75751.1 - 0.02 14.2 2.1 0.028 13.7 0.0 2.1 2 0 0 2 2 2 0 Septin Exonuc_VII_L PF02601.15 ETS75751.1 - 0.02 14.5 8.2 0.033 13.7 8.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dynamin_N PF00350.23 ETS75751.1 - 0.033 14.2 10.2 0.59 10.2 0.0 3.5 2 2 1 3 3 2 0 Dynamin family GBP PF02263.19 ETS75751.1 - 0.036 13.3 0.0 0.1 11.8 0.0 1.7 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_21 PF13304.6 ETS75751.1 - 0.043 13.6 0.2 0.69 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 ETS75751.1 - 0.048 13.8 0.7 0.048 13.8 0.7 2.6 2 1 0 2 2 1 0 Helicase HerA, central domain AAA_18 PF13238.6 ETS75751.1 - 0.071 13.6 1.3 0.57 10.7 0.0 2.6 2 1 1 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 ETS75751.1 - 0.072 12.8 0.5 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DoxX_2 PF13564.6 ETS75751.1 - 0.075 13.1 0.3 0.15 12.2 0.3 1.4 1 0 0 1 1 1 0 DoxX-like family FtsK_SpoIIIE PF01580.18 ETS75751.1 - 0.11 11.8 1.7 0.12 11.7 0.1 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.6 ETS75751.1 - 0.17 12.1 1.8 0.4 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ETS75751.1 - 0.27 11.7 7.9 3.9 8.0 7.9 2.6 1 1 0 1 1 1 0 ABC transporter DUF3040 PF11239.8 ETS75751.1 - 0.31 11.3 3.2 9.5 6.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) ATP_bind_1 PF03029.17 ETS75751.1 - 0.36 10.6 3.9 0.37 10.5 0.3 2.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 ETS75752.1 - 5e-07 29.8 0.3 4.4e-06 26.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase PQQ_2 PF13360.6 ETS75752.1 - 0.00025 20.7 0.0 0.012 15.2 0.0 2.5 1 1 1 2 2 2 1 PQQ-like domain RsgA_GTPase PF03193.16 ETS75752.1 - 0.0026 17.7 0.0 0.0072 16.2 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 ETS75752.1 - 0.15 12.6 0.0 0.15 12.6 0.0 2.6 2 1 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 ETS75752.1 - 0.18 11.6 0.1 0.18 11.6 0.1 1.9 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein SYF2 PF08231.12 ETS75752.1 - 0.61 10.5 7.0 1.1 9.7 7.0 1.3 1 0 0 1 1 1 0 SYF2 splicing factor Dynamin_N PF00350.23 ETS75752.1 - 1.5 8.9 11.9 0.79 9.8 0.0 3.4 2 2 1 3 3 3 0 Dynamin family DUF87 PF01935.17 ETS75752.1 - 5.6 7.0 9.7 1.1 9.3 0.3 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Lactonase PF10282.9 ETS75753.1 - 8.7e-49 166.6 0.1 1.1e-48 166.2 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller WD40 PF00400.32 ETS75753.1 - 0.094 13.6 0.1 0.51 11.3 0.0 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat OHCU_decarbox PF09349.10 ETS75756.1 - 2.1e-45 155.0 0.2 3.2e-45 154.4 0.2 1.3 1 0 0 1 1 1 1 OHCU decarboxylase Inhibitor_Mig-6 PF11555.8 ETS75756.1 - 0.028 14.5 4.2 0.16 12.1 4.1 2.1 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 Prp19 PF08606.11 ETS75757.1 - 4e-33 113.2 1.9 7.8e-33 112.3 1.9 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 ETS75757.1 - 1.2e-10 41.5 0.0 0.024 14.9 0.0 5.4 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ETS75757.1 - 1.8e-07 31.8 2.3 0.35 11.8 0.0 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 ETS75757.1 - 9.4e-05 21.6 0.0 0.0049 16.0 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region PQQ_2 PF13360.6 ETS75757.1 - 0.00035 20.2 1.1 0.022 14.3 0.1 2.4 1 1 1 2 2 2 1 PQQ-like domain eIF2A PF08662.11 ETS75757.1 - 0.0012 18.8 0.0 0.9 9.4 0.0 2.4 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A U-box PF04564.15 ETS75757.1 - 0.0029 17.7 0.0 0.0056 16.8 0.0 1.4 1 0 0 1 1 1 1 U-box domain V_ATPase_I_N PF18670.1 ETS75757.1 - 0.0091 16.4 1.0 0.019 15.3 0.1 1.9 2 0 0 2 2 2 1 V-type ATPase subunit I, N-terminal domain zf-Nse PF11789.8 ETS75757.1 - 0.038 13.8 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit VID27 PF08553.10 ETS75757.1 - 0.045 12.8 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain DUF1974 PF09317.11 ETS75757.1 - 0.085 12.4 0.4 0.12 11.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) DUF4023 PF13215.6 ETS75757.1 - 0.16 12.0 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) Ge1_WD40 PF16529.5 ETS75757.1 - 0.39 9.6 1.2 7.4 5.4 0.1 2.7 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5114 PF17141.4 ETS75757.1 - 0.45 11.1 5.5 0.72 10.4 0.1 3.6 5 0 0 5 5 4 0 Domain of unknown function (DUF5114) zf-RING_UBOX PF13445.6 ETS75758.1 - 0.0019 18.2 2.9 0.0043 17.0 2.9 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ETS75758.1 - 0.0027 17.6 3.1 0.0068 16.3 3.1 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ETS75758.1 - 0.0073 16.1 1.5 0.0073 16.1 1.5 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 ETS75758.1 - 0.027 14.3 1.0 0.027 14.3 1.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SelP_N PF04592.14 ETS75758.1 - 0.07 12.5 37.8 0.21 11.0 7.5 2.6 2 0 0 2 2 2 0 Selenoprotein P, N terminal region zf-C3HC4 PF00097.25 ETS75758.1 - 0.087 12.7 5.7 0.39 10.6 6.2 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ETS75758.1 - 0.12 12.5 2.0 0.21 11.8 0.5 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 ETS75758.1 - 0.15 12.2 3.0 0.14 12.3 0.8 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger SPT6_acidic PF14632.6 ETS75758.1 - 0.23 12.1 0.2 0.23 12.1 0.2 5.0 6 1 0 6 6 6 0 Acidic N-terminal SPT6 MFS_1 PF07690.16 ETS75759.1 - 4.3e-47 160.7 30.4 4.3e-47 160.7 30.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS75759.1 - 5.8e-05 22.5 5.8 5.8e-05 22.5 5.8 2.0 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 ETS75759.1 - 0.00034 19.2 1.9 0.00048 18.7 1.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 ETS75759.1 - 0.0014 17.1 0.5 0.0014 17.1 0.5 2.5 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Thioredoxin PF00085.20 ETS75760.1 - 2.1e-11 43.7 0.1 3.9e-10 39.6 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin RicinB_lectin_2 PF14200.6 ETS75761.1 - 9.6e-19 67.9 0.5 3.7e-11 43.6 0.6 2.2 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 ETS75761.1 - 0.02 15.2 0.0 0.18 12.1 0.0 1.9 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain Peroxidase_2 PF01328.17 ETS75762.1 - 3.3e-45 154.9 0.0 4.1e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Fungal_trans_2 PF11951.8 ETS75763.1 - 0.00038 19.4 4.2 0.00068 18.6 4.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dioxygenase_C PF00775.21 ETS75764.1 - 4.5e-10 39.3 0.0 4.2e-08 32.8 0.0 2.3 1 1 0 1 1 1 1 Dioxygenase GRDP-like PF07173.12 ETS75765.1 - 5.9e-21 75.6 7.1 9.6e-15 55.5 0.6 3.4 3 1 1 4 4 4 2 Glycine-rich domain-containing protein-like Dioxygenase_C PF00775.21 ETS75766.1 - 6.7e-09 35.4 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase Tyrosinase PF00264.20 ETS75767.1 - 2e-29 103.5 7.1 5e-29 102.2 7.1 1.6 1 1 0 1 1 1 1 Common central domain of tyrosinase Dioxygenase_C PF00775.21 ETS75768.1 - 1.9e-06 27.4 0.0 3.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase Folliculin_C PF16692.5 ETS75768.1 - 0.21 11.3 0.0 0.72 9.5 0.0 1.8 1 1 1 2 2 2 0 Folliculin C-terminal domain Ank_2 PF12796.7 ETS75769.1 - 1.7e-47 159.9 2.4 3.1e-09 37.3 0.0 10.4 3 2 9 13 13 13 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS75769.1 - 9.4e-37 124.9 13.2 1.4e-08 35.1 0.0 12.7 11 3 2 13 13 13 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS75769.1 - 6.9e-33 109.0 20.1 0.00091 19.5 0.0 15.7 18 0 0 18 18 18 8 Ankyrin repeat Ank_5 PF13857.6 ETS75769.1 - 3.2e-25 87.9 12.9 0.03 14.6 0.0 11.7 10 3 3 13 13 13 6 Ankyrin repeats (many copies) Ank PF00023.30 ETS75769.1 - 4.4e-18 64.8 26.4 0.017 15.5 0.0 11.9 13 1 0 13 13 13 5 Ankyrin repeat Clr5 PF14420.6 ETS75769.1 - 1.3e-14 54.2 5.2 2.8e-14 53.1 5.2 1.6 1 0 0 1 1 1 1 Clr5 domain DUF4899 PF16240.5 ETS75769.1 - 0.035 13.3 1.2 7.2 5.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4899) tRNA_NucTran2_2 PF13735.6 ETS75769.1 - 0.091 12.7 0.7 0.21 11.6 0.7 1.5 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative GFO_IDH_MocA PF01408.22 ETS75772.1 - 6.1e-18 65.8 0.1 1.3e-17 64.8 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 ETS75772.1 - 0.0034 18.0 0.1 0.007 17.0 0.1 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF2306 PF10067.9 ETS75773.1 - 1.6e-35 122.4 11.2 3.4e-35 121.4 8.1 2.0 1 1 1 2 2 2 1 Predicted membrane protein (DUF2306) TIC20 PF16166.5 ETS75773.1 - 0.019 14.7 0.3 0.033 14.0 0.3 1.5 1 1 0 1 1 1 0 Chloroplast import apparatus Tic20-like DUF420 PF04238.12 ETS75773.1 - 0.053 13.8 2.8 2.2 8.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF420) Aldedh PF00171.22 ETS75774.1 - 2.2e-138 461.6 0.0 2.6e-138 461.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DLH PF01738.18 ETS75775.1 - 5.5e-20 71.9 0.0 1.8e-19 70.2 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF3712 PF12505.8 ETS75776.1 - 3.8e-22 78.9 0.1 7.1e-22 78.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) DUF1772 PF08592.11 ETS75776.1 - 0.018 15.3 0.2 0.046 14.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Pox_EPC_I2-L1 PF12575.8 ETS75776.1 - 0.13 12.5 0.4 0.52 10.6 0.1 2.1 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 CRAL_TRIO PF00650.20 ETS75777.1 - 4.2e-38 130.6 0.0 1.1e-37 129.2 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ETS75777.1 - 5.3e-11 42.5 0.4 2.1e-10 40.6 0.4 2.1 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ETS75777.1 - 4.8e-07 30.0 0.0 8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain FMO-like PF00743.19 ETS75778.1 - 7.9e-14 51.0 0.0 5.2e-12 45.0 0.0 2.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ETS75778.1 - 1.2e-11 44.4 0.0 3.2e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS75778.1 - 1.6e-09 37.4 0.0 1.9e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 ETS75778.1 - 2.2e-08 34.2 0.0 2.3e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS75778.1 - 1.5e-07 31.0 0.0 4.6e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS75778.1 - 3e-07 29.9 0.2 2.2e-05 23.7 0.0 3.0 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ETS75778.1 - 9.2e-06 25.5 1.0 0.00018 21.3 0.3 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS75778.1 - 0.00013 21.1 0.5 0.0061 15.7 0.1 3.1 4 0 0 4 4 4 1 FAD binding domain Lycopene_cycl PF05834.12 ETS75778.1 - 0.0014 17.8 0.1 0.15 11.1 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein Amino_oxidase PF01593.24 ETS75778.1 - 0.0053 16.1 0.0 0.0073 15.6 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 ETS75778.1 - 0.0099 16.4 0.0 7.1 7.3 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ETS75778.1 - 0.015 14.6 0.1 0.032 13.6 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS75778.1 - 0.017 15.1 1.1 3.6 7.6 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Mqo PF06039.15 ETS75778.1 - 0.041 12.4 0.3 0.87 8.1 0.0 2.3 3 0 0 3 3 3 0 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.22 ETS75778.1 - 0.095 11.8 0.1 0.19 10.8 0.1 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 ETS75778.1 - 0.17 10.5 0.3 0.45 9.2 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein Abhydrolase_3 PF07859.13 ETS75779.1 - 5.2e-25 88.6 0.0 6.8e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS75779.1 - 1.8e-09 37.0 0.0 2.6e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 ETS75779.1 - 0.14 11.0 0.0 0.62 8.9 0.0 1.8 2 0 0 2 2 2 0 Carboxylesterase family adh_short PF00106.25 ETS75780.1 - 8.2e-42 142.9 0.0 1.3e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS75780.1 - 1.1e-30 107.0 0.0 1.5e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS75780.1 - 2e-10 40.9 0.2 6.3e-10 39.2 0.2 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS75780.1 - 1.8e-05 24.3 0.0 2.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS75780.1 - 0.00013 21.1 0.1 0.00019 20.5 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.19 ETS75780.1 - 0.0023 17.3 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1776 PF08643.10 ETS75780.1 - 0.016 14.6 1.0 0.022 14.1 0.0 1.7 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Zn_clus PF00172.18 ETS75781.1 - 1.8e-09 37.5 9.3 4.6e-09 36.2 9.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 ETS75782.1 - 4.3e-74 249.9 0.0 5.4e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PGAP1 PF07819.13 ETS75783.1 - 0.056 13.1 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein HET PF06985.11 ETS75784.1 - 1.4e-13 51.4 2.4 2.8e-13 50.4 2.4 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 ETS75785.1 - 4.2e-23 81.8 0.1 7.8e-19 67.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS75785.1 - 5.1e-12 45.9 0.0 7.8e-10 38.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS75785.1 - 3.2e-10 40.2 0.0 4.8e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS75785.1 - 2.9e-05 23.7 0.0 4.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ETS75785.1 - 0.044 12.9 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 ETS75785.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3425 PF11905.8 ETS75786.1 - 2.9e-21 75.7 0.0 6.5e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) FAD_binding_4 PF01565.23 ETS75788.1 - 3.6e-17 62.4 4.7 8e-16 58.0 4.7 2.5 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS75788.1 - 2.9e-10 40.1 0.0 5.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans_2 PF11951.8 ETS75789.1 - 4.7e-14 52.0 0.5 6.8e-14 51.5 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PGAP1 PF07819.13 ETS75790.1 - 2.9e-05 23.9 0.3 8.8e-05 22.3 0.2 1.7 1 1 1 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 ETS75790.1 - 0.00028 21.6 0.2 0.00054 20.6 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS75790.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 ETS75790.1 - 0.0015 18.1 0.0 0.0055 16.2 0.0 1.8 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 ETS75790.1 - 0.0058 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.13 ETS75790.1 - 0.006 16.5 0.0 0.016 15.1 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.12 ETS75790.1 - 0.0083 16.1 0.2 0.013 15.4 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.20 ETS75790.1 - 0.014 15.1 0.1 0.045 13.4 0.1 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.11 ETS75790.1 - 0.074 12.4 0.1 5.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Aldedh PF00171.22 ETS75791.1 - 1.4e-121 406.3 2.3 1.6e-121 406.1 2.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ETS75791.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Aldedh PF00171.22 ETS75792.1 - 4e-26 91.6 0.1 4.5e-26 91.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pyr_redox_2 PF07992.14 ETS75793.1 - 0.00037 19.8 0.1 0.016 14.5 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS75793.1 - 0.017 14.4 2.8 0.14 11.4 2.8 2.4 1 1 0 1 1 1 0 FAD binding domain Erf4 PF10256.9 ETS75793.1 - 0.03 14.4 0.1 0.17 12.0 0.1 2.2 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family NAD_binding_9 PF13454.6 ETS75793.1 - 0.033 14.2 3.9 2.6 8.0 0.4 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ETS75793.1 - 0.1 12.8 0.1 0.27 11.5 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS75793.1 - 0.1 12.1 0.4 9 5.8 0.2 2.3 1 1 1 2 2 2 0 FAD dependent oxidoreductase IlvN PF07991.12 ETS75793.1 - 0.15 11.6 0.0 0.76 9.3 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain PHZA_PHZB PF03284.13 ETS75794.1 - 4.8e-19 68.5 0.0 6.4e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis protein A/B EutQ PF06249.12 ETS75795.1 - 1.8e-07 31.0 0.1 2.2e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 ETS75795.1 - 4.6e-07 29.4 0.1 6e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 ETS75795.1 - 0.0022 17.6 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain KduI PF04962.12 ETS75795.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 KduI/IolB family Fungal_trans_2 PF11951.8 ETS75796.1 - 1.8e-08 33.6 1.4 2.1e-08 33.4 1.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain SLAC1 PF03595.17 ETS75797.1 - 1.4e-57 195.4 32.5 1.6e-57 195.3 32.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Sugar_tr PF00083.24 ETS75798.1 - 1.2e-76 258.5 17.9 1.4e-76 258.3 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS75798.1 - 5.9e-34 117.5 44.1 2.2e-28 99.2 26.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS75798.1 - 0.0053 15.7 16.5 0.07 12.0 9.5 2.2 2 0 0 2 2 2 2 MFS_1 like family Glyco_hydro_39 PF01229.17 ETS75799.1 - 1.8e-05 23.6 0.2 2.5e-05 23.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Glyco_hydro_127 PF07944.12 ETS75800.1 - 7.3e-114 381.1 0.4 9e-114 380.8 0.4 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 SCNM1_acidic PF15805.5 ETS75800.1 - 0.06 13.1 0.1 0.2 11.4 0.1 1.9 1 0 0 1 1 1 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 Fungal_trans PF04082.18 ETS75801.1 - 8.9e-09 34.7 5.2 9.3e-08 31.4 4.6 2.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS75801.1 - 1.6e-05 24.9 10.7 3.9e-05 23.7 10.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 ETS75801.1 - 0.00024 21.7 15.0 0.073 13.9 5.8 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ETS75801.1 - 0.0018 18.6 1.3 0.0018 18.6 1.3 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 ETS75801.1 - 0.011 16.2 16.3 0.051 14.1 7.0 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3446 PF11928.8 ETS75801.1 - 5.2 7.4 7.8 1.3 9.4 3.6 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain Epimerase PF01370.21 ETS75802.1 - 3.5e-08 33.2 0.0 7.5e-08 32.1 0.0 1.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS75802.1 - 2.7e-07 30.7 0.0 4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ETS75802.1 - 9.5e-05 21.7 0.0 0.00019 20.7 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 ETS75802.1 - 0.0016 18.9 0.0 0.0031 18.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 ETS75802.1 - 0.0047 16.9 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 ETS75802.1 - 0.033 13.3 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain EthD PF07110.11 ETS75803.1 - 4.1e-22 79.1 0.4 4.8e-22 78.9 0.4 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 ETS75803.1 - 0.0013 19.1 0.1 0.002 18.6 0.1 1.3 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase DUF1205 PF06722.12 ETS75803.1 - 0.068 13.3 0.0 0.098 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) NAD_binding_2 PF03446.15 ETS75804.1 - 1.3e-34 119.7 0.0 2.7e-34 118.6 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ETS75804.1 - 6.4e-15 55.5 2.5 1.1e-14 54.7 2.5 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ETS75804.1 - 6.2e-05 23.5 0.0 0.00018 22.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Glyco_transf_15 PF01793.16 ETS75805.1 - 3.3e-95 319.1 6.5 1.6e-62 211.6 0.9 2.0 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase ILVD_EDD PF00920.21 ETS75806.1 - 2.7e-209 696.1 0.1 3.1e-209 695.9 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Myb_DNA-binding PF00249.31 ETS75807.1 - 0.0025 18.0 0.2 0.017 15.3 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ETS75808.1 - 1.5e-15 57.1 1.2 4.8e-09 36.3 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ETS75808.1 - 6.1e-09 36.0 5.2 0.00022 21.4 0.0 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain TMEM18 PF14770.6 ETS75809.1 - 0.12 12.4 0.2 0.21 11.6 0.2 1.5 1 1 0 1 1 1 0 Transmembrane protein 18 CAF1C_H4-bd PF12265.8 ETS75810.1 - 1.8e-13 50.5 0.0 6.8e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 ETS75810.1 - 3.1e-12 46.8 7.6 5.6e-06 27.0 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS75810.1 - 4.5e-08 33.3 0.7 0.0011 19.2 0.1 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ETS75810.1 - 0.007 15.1 0.4 0.007 15.1 0.4 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 ETS75810.1 - 0.99 8.3 3.3 0.65 8.8 0.9 1.8 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Chs7 PF12271.8 ETS75812.1 - 4.7e-125 416.7 16.3 5.4e-125 416.5 16.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Sid-5 PF17204.3 ETS75812.1 - 4.4 7.5 6.1 0.65 10.2 0.8 2.3 2 0 0 2 2 2 0 Sid-5 family DUF4604 PF15377.6 ETS75813.1 - 4e-31 108.8 19.0 4.6e-31 108.6 19.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Glyco_transf_8 PF01501.20 ETS75814.1 - 8.4e-09 35.3 3.6 3.8e-08 33.2 3.6 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 ETS75814.1 - 0.16 11.3 0.0 0.35 10.2 0.0 1.5 1 1 0 1 1 1 0 Mannosyltransferase putative DHQ_synthase PF01761.20 ETS75815.1 - 1.5e-52 178.4 0.0 2.2e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 ETS75815.1 - 4.7e-11 42.9 0.0 7.5e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 ETS75815.1 - 0.0017 17.3 0.0 0.0032 16.3 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Methyltransf_24 PF13578.6 ETS75816.1 - 2.6e-13 50.9 0.0 5.2e-13 49.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 ETS75816.1 - 6.1e-11 41.9 0.0 7.9e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase CmcI PF04989.12 ETS75816.1 - 0.0061 16.3 0.0 0.0093 15.7 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase Vps16_C PF04840.12 ETS75817.1 - 0.05 12.6 0.0 0.26 10.3 0.0 1.8 2 0 0 2 2 2 0 Vps16, C-terminal region GalP_UDP_tr_C PF02744.17 ETS75817.1 - 0.16 11.7 1.3 0.32 10.7 1.3 1.5 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Aldo_ket_red PF00248.21 ETS75818.1 - 1.8e-45 155.4 0.1 1.2e-32 113.3 0.1 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family NAD_binding_4 PF07993.12 ETS75819.1 - 2.6e-33 115.3 0.0 4.2e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 ETS75819.1 - 9.8e-22 77.1 0.0 1.4e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 ETS75819.1 - 3.9e-06 26.5 0.0 7.2e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 ETS75819.1 - 7.1e-05 23.1 0.0 0.00016 22.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.24 ETS75819.1 - 0.0099 16.3 0.0 0.03 14.7 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 ETS75819.1 - 0.012 15.5 0.5 0.029 14.3 0.0 1.9 2 0 0 2 2 2 0 KR domain 3Beta_HSD PF01073.19 ETS75819.1 - 0.027 13.5 0.0 0.07 12.1 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family WD40 PF00400.32 ETS75820.1 - 1.8e-28 98.2 8.4 3.3e-06 27.7 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS75820.1 - 4.2e-06 27.0 0.0 2.1 8.7 0.0 4.1 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS75820.1 - 0.00075 18.6 0.0 3 6.7 0.0 3.4 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-NADH-PPase PF09297.11 ETS75820.1 - 0.014 15.0 1.2 0.05 13.3 1.2 2.0 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain PD40 PF07676.12 ETS75820.1 - 0.053 13.5 0.1 26 4.9 0.0 4.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Zn_Tnp_IS1595 PF12760.7 ETS75820.1 - 0.074 13.0 2.4 0.17 11.9 2.4 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Nudix_N_2 PF14803.6 ETS75820.1 - 0.14 12.1 4.3 0.078 12.9 1.4 2.0 2 0 0 2 2 2 0 Nudix N-terminal Thioredoxin PF00085.20 ETS75821.1 - 4e-26 91.0 0.0 5.7e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 ETS75821.1 - 1e-07 32.1 0.0 2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 ETS75821.1 - 3.2e-07 30.0 0.0 4e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 ETS75821.1 - 9.5e-06 25.9 0.0 0.00052 20.3 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 ETS75821.1 - 1.3e-05 25.6 0.2 8.2e-05 23.0 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 ETS75821.1 - 0.0015 18.4 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 ETS75821.1 - 0.0076 16.0 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 ETS75821.1 - 0.035 14.3 0.0 0.19 12.0 0.0 2.1 1 1 1 2 2 2 0 Glutaredoxin TrbC_Ftype PF09673.10 ETS75821.1 - 0.093 12.8 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein HyaE PF07449.11 ETS75821.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 ETS75821.1 - 0.12 12.0 0.1 0.19 11.4 0.0 1.5 2 0 0 2 2 2 0 Redoxin DIM1 PF02966.16 ETS75821.1 - 0.19 11.5 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Amidoligase_2 PF12224.8 ETS75822.1 - 1.4e-14 54.4 0.0 7.6e-10 38.9 0.0 2.0 2 0 0 2 2 2 2 Putative amidoligase enzyme eRF1_1 PF03463.15 ETS75823.1 - 8.9e-45 151.8 0.1 1.6e-44 151.1 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 ETS75823.1 - 1e-19 71.2 0.0 1.9e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 ETS75823.1 - 1.5e-19 70.6 0.0 3.3e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 Aldo_ket_red PF00248.21 ETS75824.1 - 3.7e-41 141.2 0.0 8.8e-39 133.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.24 ETS75825.1 - 7.1e-86 288.8 20.1 8.4e-86 288.6 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS75825.1 - 2.6e-18 66.1 28.0 2.6e-18 66.1 28.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ETS75825.1 - 2.1e-07 30.6 2.4 2.1e-07 30.6 2.4 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 ETS75825.1 - 0.0012 17.8 4.9 0.0012 17.8 4.9 2.1 2 0 0 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 ETS75825.1 - 0.0079 14.8 3.1 0.0079 14.8 3.1 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein DUF2628 PF10947.8 ETS75825.1 - 1.9 8.9 10.9 0.29 11.5 5.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) LapA_dom PF06305.11 ETS75826.1 - 0.05 13.4 0.2 0.086 12.7 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Epimerase PF01370.21 ETS75827.1 - 5.7e-10 39.1 0.0 5.4e-09 35.9 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS75827.1 - 8.1e-05 22.6 0.0 0.00029 20.8 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS75827.1 - 9.6e-05 22.0 0.0 0.00045 19.8 0.0 2.1 1 1 2 3 3 3 1 NmrA-like family 3Beta_HSD PF01073.19 ETS75827.1 - 0.00032 19.8 0.0 0.00064 18.8 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ETS75827.1 - 0.0018 17.7 0.0 0.014 14.8 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 ETS75827.1 - 0.018 15.4 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 ETS75827.1 - 0.035 13.2 0.0 0.15 11.2 0.0 2.0 2 1 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 ETS75827.1 - 0.073 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein KR PF08659.10 ETS75827.1 - 0.087 12.7 0.1 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 KR domain F420_oxidored PF03807.17 ETS75827.1 - 0.094 13.3 0.0 0.25 12.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RNA_pol_3_Rpc31 PF11705.8 ETS75828.1 - 4.7e-48 164.4 12.5 6.2e-48 164.0 12.5 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 AAA PF00004.29 ETS75830.1 - 2e-16 60.6 0.7 6.4e-14 52.5 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS75830.1 - 0.014 15.6 4.8 0.12 12.6 0.1 3.3 3 1 1 4 4 4 0 AAA domain AAA_30 PF13604.6 ETS75830.1 - 0.015 15.0 0.2 0.27 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ETS75830.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ETS75830.1 - 0.056 13.8 1.4 0.55 10.6 1.4 2.7 1 1 0 1 1 1 0 AAA ATPase domain Ion_trans PF00520.31 ETS75831.1 - 2.5e-07 30.2 26.8 2.2e-05 23.8 26.8 2.3 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 ETS75831.1 - 1.4e-06 27.3 18.2 5.7e-05 22.0 18.2 2.2 1 1 0 1 1 1 1 Polycystin cation channel Ly49 PF08391.10 ETS75831.1 - 0.1 12.9 0.0 0.5 10.7 0.0 2.1 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Ac76 PF05814.11 ETS75831.1 - 0.96 9.5 7.2 0.91 9.6 0.5 3.1 2 0 0 2 2 2 0 Orf76 (Ac76) Sugar_tr PF00083.24 ETS75832.1 - 1.2e-39 136.4 18.3 3.6e-39 134.9 18.3 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS75832.1 - 1.9e-33 115.9 21.9 1.9e-26 92.8 8.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 ETS75832.1 - 0.025 13.5 7.7 0.052 12.5 0.5 2.5 3 0 0 3 3 3 0 Sugar-tranasporters, 12 TM Macro PF01661.21 ETS75833.1 - 5.3e-36 123.2 0.0 9.2e-36 122.5 0.0 1.4 1 0 0 1 1 1 1 Macro domain Stc1 PF12898.7 ETS75834.1 - 0.027 15.0 7.3 0.14 12.8 0.4 2.7 2 0 0 2 2 2 0 Stc1 domain Elf1 PF05129.13 ETS75834.1 - 0.079 13.0 7.6 1.6 8.8 0.3 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-TFIIB PF13453.6 ETS75834.1 - 1.4 8.3 11.0 0.19 11.1 1.9 2.6 2 0 0 2 2 2 0 Transcription factor zinc-finger Cyt-b5 PF00173.28 ETS75835.1 - 2.2e-23 82.2 0.0 2.3e-09 37.3 0.0 4.8 4 0 0 4 4 4 4 Cytochrome b5-like Heme/Steroid binding domain ADH_N PF08240.12 ETS75836.1 - 4.1e-24 84.6 5.0 6.4e-24 83.9 5.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS75836.1 - 3.1e-18 66.0 0.0 5.5e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS75836.1 - 2.9e-09 38.1 0.0 5.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ETS75836.1 - 0.00035 19.9 0.0 0.00061 19.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Haem_bd PF14376.6 ETS75836.1 - 0.019 14.9 0.1 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 Haem-binding domain 2-Hacid_dh_C PF02826.19 ETS75836.1 - 0.02 14.3 0.1 0.033 13.6 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DHHC PF01529.20 ETS75837.1 - 8.8e-14 51.8 0.4 8.8e-14 51.8 0.4 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase RNase_T PF00929.24 ETS75839.1 - 1.1e-18 68.3 0.0 1.8e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 ETS75839.1 - 0.021 14.6 0.0 0.12 12.0 0.0 1.9 1 1 0 1 1 1 0 3'-5' exonuclease QWRF PF04484.12 ETS75841.1 - 2.7 7.6 8.3 2.7 7.6 8.3 1.2 1 0 0 1 1 1 0 QWRF family PPR_2 PF13041.6 ETS75842.1 - 1.8e-48 162.5 8.6 1.4e-08 34.8 0.0 13.4 11 4 5 16 16 16 7 PPR repeat family PPR_3 PF13812.6 ETS75842.1 - 5.5e-31 106.5 1.5 0.0078 16.3 0.0 10.9 8 3 4 12 12 12 7 Pentatricopeptide repeat domain PPR PF01535.20 ETS75842.1 - 6e-27 92.0 21.4 0.00082 19.5 0.0 13.6 15 1 0 15 15 15 6 PPR repeat PPR_1 PF12854.7 ETS75842.1 - 3.5e-25 87.4 0.2 3.1e-07 30.0 0.0 9.6 11 0 0 11 11 11 6 PPR repeat PPR_long PF17177.4 ETS75842.1 - 1.4e-19 70.4 13.3 5e-08 32.6 0.1 6.8 2 2 5 7 7 7 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 ETS75842.1 - 0.00022 21.6 0.0 0.0047 17.3 0.0 3.1 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 ETS75842.1 - 0.0037 17.1 0.1 0.064 13.1 0.0 3.2 3 1 1 4 4 4 1 Mitochondrial ATPase expression TPR_MalT PF17874.1 ETS75842.1 - 7.9 5.7 10.4 22 4.3 0.1 4.3 5 0 0 5 5 5 0 MalT-like TPR region CDC27 PF09507.10 ETS75843.1 - 3.3e-86 290.3 25.7 8.4e-86 289.0 25.7 1.6 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Fe_dep_repress PF01325.19 ETS75843.1 - 0.0017 18.5 0.1 2.8 8.2 0.0 2.5 2 0 0 2 2 2 2 Iron dependent repressor, N-terminal DNA binding domain TSP9 PF11493.8 ETS75843.1 - 5.1 7.8 11.0 0.43 11.3 0.9 3.2 3 0 0 3 3 3 0 Thylakoid soluble phosphoprotein TSP9 zf-C3HC4_2 PF13923.6 ETS75844.1 - 1.7e-12 46.9 16.8 1.9e-11 43.6 12.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ETS75844.1 - 4.6e-08 32.8 18.2 1e-07 31.7 12.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS75844.1 - 1.8e-07 30.9 9.9 1.8e-07 30.9 9.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS75844.1 - 5.2e-07 29.6 10.5 5.2e-07 29.6 10.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger SAP PF02037.27 ETS75844.1 - 6.2e-07 29.0 0.2 1.3e-06 28.0 0.2 1.6 1 0 0 1 1 1 1 SAP domain zf-RING_2 PF13639.6 ETS75844.1 - 7.8e-07 29.3 18.1 3.1e-06 27.4 12.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.6 ETS75844.1 - 1.3e-06 28.2 6.6 1.3e-05 24.9 4.4 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 ETS75844.1 - 4.2e-06 26.5 12.8 0.00039 20.2 10.6 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ETS75844.1 - 4.2e-06 26.6 12.3 4.2e-06 26.6 12.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ETS75844.1 - 1.6e-05 24.9 16.0 2.2e-05 24.5 11.7 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 ETS75844.1 - 0.0003 21.0 5.4 0.0003 21.0 5.4 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 ETS75844.1 - 0.016 15.3 6.9 0.037 14.2 6.9 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 U-box PF04564.15 ETS75844.1 - 0.03 14.5 0.0 0.36 11.1 0.0 2.4 2 0 0 2 2 2 0 U-box domain Mob_synth_C PF06463.13 ETS75844.1 - 0.17 11.9 8.3 0.07 13.1 5.3 1.9 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C zf-RING_4 PF14570.6 ETS75844.1 - 0.99 9.3 14.1 0.2 11.4 6.2 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Snf7 PF03357.21 ETS75845.1 - 6.7e-20 71.4 21.4 1.2e-19 70.6 21.4 1.5 1 0 0 1 1 1 1 Snf7 Cu-oxidase_4 PF02578.15 ETS75845.1 - 0.19 11.3 1.8 1.7 8.2 0.3 2.2 2 0 0 2 2 2 0 Multi-copper polyphenol oxidoreductase laccase DUF948 PF06103.11 ETS75845.1 - 7.2 7.0 9.7 37 4.7 1.2 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Abhydrolase_2 PF02230.16 ETS75846.1 - 0.032 14.0 0.1 0.14 12.0 0.1 1.9 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Nitroreductase PF00881.24 ETS75847.1 - 3.2e-20 72.9 1.6 6.1e-19 68.7 1.6 2.3 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ETS75847.1 - 0.13 11.8 0.0 15 5.1 0.0 2.2 2 0 0 2 2 2 0 Putative TM nitroreductase MT PF12777.7 ETS75849.1 - 0.013 14.6 0.8 0.027 13.5 0.8 1.6 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor P22_CoatProtein PF11651.8 ETS75849.1 - 0.098 11.2 0.2 0.17 10.5 0.2 1.3 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 TPR_6 PF13174.6 ETS75849.1 - 0.35 11.6 2.0 11 6.9 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat COG5 PF10392.9 ETS75849.1 - 1.2 9.3 14.4 11 6.2 7.4 3.2 3 1 0 3 3 3 0 Golgi transport complex subunit 5 TipAS PF07739.13 ETS75849.1 - 1.3 9.6 7.7 1.3 9.6 0.2 3.1 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain DUF1515 PF07439.11 ETS75849.1 - 1.6 8.7 10.3 0.29 11.2 0.5 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) Exonuc_VII_L PF02601.15 ETS75849.1 - 2 7.9 16.2 1.8 8.1 8.1 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit DEAD PF00270.29 ETS75850.1 - 8.6e-44 149.4 0.2 1.4e-43 148.7 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS75850.1 - 6.1e-19 68.4 0.0 2.9e-18 66.2 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ETS75850.1 - 2.7e-14 53.1 0.0 5.3e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ETS75850.1 - 3.9e-06 27.0 0.0 9.3e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pro-kuma_activ PF09286.11 ETS75851.1 - 8.3e-41 139.6 0.0 2.1e-40 138.3 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ETS75851.1 - 2.4e-07 30.3 0.9 4.1e-07 29.5 0.9 1.3 1 0 0 1 1 1 1 Subtilase family TRAPPC-Trs85 PF12739.7 ETS75852.1 - 1.2e-113 380.1 0.0 3.6e-113 378.6 0.1 1.6 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Catalase PF00199.19 ETS75853.1 - 4.2e-23 82.1 0.0 6.3e-21 74.9 0.0 2.0 1 1 0 1 1 1 1 Catalase adh_short PF00106.25 ETS75854.1 - 5.2e-36 123.9 0.0 6.9e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS75854.1 - 3.2e-31 108.7 0.0 4.2e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS75854.1 - 0.0016 18.3 0.1 0.0034 17.3 0.1 1.5 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ETS75854.1 - 0.17 11.8 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PEP_mutase PF13714.6 ETS75856.1 - 6.7e-43 146.8 0.1 8.5e-43 146.5 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 ETS75856.1 - 4.9e-18 64.9 0.0 7.5e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 Isocitrate lyase family DUF1275 PF06912.11 ETS75857.1 - 4e-45 154.1 10.8 5.1e-45 153.8 10.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Phage_holin_5_2 PF16079.5 ETS75857.1 - 1 9.7 5.5 0.57 10.5 0.4 2.8 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V MFS_1 PF07690.16 ETS75858.1 - 9.8e-54 182.6 26.6 4.7e-53 180.4 23.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS75858.1 - 4.1e-14 52.3 2.6 4.1e-14 52.3 2.6 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 ETS75858.1 - 1.6e-08 33.5 5.2 2.8e-08 32.7 5.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 ETS75858.1 - 1e-05 24.1 5.4 1e-05 24.1 5.4 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_5 PF05631.14 ETS75858.1 - 9.4e-05 21.5 2.4 9.4e-05 21.5 2.4 2.3 2 1 0 2 2 2 1 Sugar-tranasporters, 12 TM Phage_holin_2_4 PF16082.5 ETS75858.1 - 0.15 11.8 2.8 5.4 6.8 0.0 3.4 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like V-SNARE_C PF12352.8 ETS75859.1 - 8.1e-15 54.9 0.3 2.1e-14 53.6 0.3 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 ETS75859.1 - 4.2e-05 23.4 0.2 0.00047 20.0 0.0 2.5 2 1 1 3 3 3 1 Sec20 Sigma70_r4 PF04545.16 ETS75859.1 - 0.03 13.8 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 E2F_TDP PF02319.20 ETS75859.1 - 0.048 13.7 0.1 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain TPR_MLP1_2 PF07926.12 ETS75859.1 - 0.15 12.1 9.2 1 9.4 4.6 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein KxDL PF10241.9 ETS75859.1 - 0.3 11.4 6.8 11 6.4 0.1 3.4 3 1 0 3 3 3 0 Uncharacterized conserved protein TPK_catalytic PF04263.16 ETS75860.1 - 3.5e-28 98.0 0.0 5.7e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 ETS75860.1 - 2.1e-22 78.6 0.0 3.7e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CHCH PF06747.13 ETS75861.1 - 1.6e-06 28.1 5.7 2.6e-06 27.4 5.7 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 ETS75861.1 - 1.3 9.5 6.9 0.1 13.0 2.1 1.7 2 0 0 2 2 2 0 GCK domain Zn_clus PF00172.18 ETS75862.1 - 0.0097 16.0 10.4 0.016 15.3 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 ETS75863.1 - 1.5e-85 287.8 25.4 1.7e-85 287.6 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS75863.1 - 1.4e-16 60.4 34.2 6.9e-16 58.1 28.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS75863.1 - 9.9e-08 30.9 21.6 3.2e-05 22.7 1.5 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein Folate_carrier PF01770.18 ETS75863.1 - 0.009 14.8 8.0 0.02 13.6 8.0 1.5 1 1 0 1 1 1 1 Reduced folate carrier Alpha-amylase PF00128.24 ETS75864.1 - 2.7e-107 359.2 0.0 4e-107 358.7 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Macoilin PF09726.9 ETS75866.1 - 0.25 9.9 5.7 0.35 9.4 5.7 1.2 1 0 0 1 1 1 0 Macoilin family SMYLE_N PF18615.1 ETS75866.1 - 2.4 7.6 7.9 4.5 6.7 7.9 1.4 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain BAF1_ABF1 PF04684.13 ETS75866.1 - 2.7 6.9 6.9 3.8 6.5 6.9 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SKG6 PF08693.10 ETS75867.1 - 0.066 12.6 3.0 0.17 11.3 3.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PBP PF01161.20 ETS75868.1 - 1.8e-18 67.1 0.0 2.3e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_C14 PF00656.22 ETS75870.1 - 7.2e-59 199.7 0.0 8.8e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 ETS75870.1 - 0.016 15.2 0.2 0.1 12.6 0.0 2.3 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain WW PF00397.26 ETS75871.1 - 5.2e-08 32.8 5.1 1.1e-07 31.7 5.1 1.6 1 0 0 1 1 1 1 WW domain KinB_sensor PF16767.5 ETS75871.1 - 0.00061 20.3 2.0 0.0011 19.4 2.0 1.3 1 0 0 1 1 1 1 Sensor domain of alginate biosynthesis sensor protein KinB DUF5353 PF17304.2 ETS75872.1 - 3.1e-15 55.7 2.1 5e-15 55.0 2.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5353) IER PF05760.12 ETS75872.1 - 0.0021 18.4 0.0 0.0026 18.1 0.0 1.1 1 0 0 1 1 1 1 Immediate early response protein (IER) DUF1682 PF07946.14 ETS75872.1 - 2.1 7.5 7.3 2.7 7.1 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TPR_MLP1_2 PF07926.12 ETS75873.1 - 0.00013 22.1 44.3 0.02 14.9 2.1 3.9 1 1 3 4 4 4 3 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 ETS75873.1 - 0.00037 19.7 27.2 0.0004 19.6 5.1 2.7 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Flagellin_C PF00700.21 ETS75873.1 - 0.0021 18.4 12.7 0.56 10.6 1.4 4.0 1 1 2 3 3 3 2 Bacterial flagellin C-terminal helical region Spc7 PF08317.11 ETS75873.1 - 0.0058 15.5 37.8 0.044 12.6 12.1 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein Cast PF10174.9 ETS75873.1 - 0.054 11.7 29.6 0.075 11.2 29.6 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Fez1 PF06818.15 ETS75873.1 - 0.056 13.9 32.2 0.3 11.5 19.7 3.1 1 1 2 3 3 3 0 Fez1 GAS PF13851.6 ETS75873.1 - 0.97 8.7 30.8 0.36 10.1 9.9 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding EzrA PF06160.12 ETS75873.1 - 1.1 7.3 24.4 8.2 4.5 24.4 2.2 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA HMMR_N PF15905.5 ETS75873.1 - 1.4 8.3 34.4 0.16 11.4 18.3 2.4 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF5082 PF16888.5 ETS75873.1 - 1.7 9.0 26.7 0.085 13.1 11.5 3.9 1 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF4200 PF13863.6 ETS75873.1 - 1.8 9.0 29.6 0.083 13.3 11.6 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) KxDL PF10241.9 ETS75873.1 - 2.7 8.3 22.2 12 6.3 1.0 4.7 1 1 3 4 4 4 0 Uncharacterized conserved protein FPP PF05911.11 ETS75873.1 - 2.8 6.0 34.8 0.36 9.0 28.9 1.9 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Tropomyosin PF00261.20 ETS75873.1 - 3.6 6.9 37.2 0.72 9.2 17.6 2.7 1 1 1 2 2 2 0 Tropomyosin ADIP PF11559.8 ETS75873.1 - 3.8 7.6 38.3 5 7.2 10.7 4.1 2 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Spore_III_AB PF09548.10 ETS75873.1 - 4.2 7.4 12.9 0.03 14.4 1.1 2.8 1 1 1 2 2 1 0 Stage III sporulation protein AB (spore_III_AB) Filament PF00038.21 ETS75873.1 - 4.4 6.8 33.4 4.3 6.8 3.5 2.9 1 1 2 3 3 3 0 Intermediate filament protein DUF1664 PF07889.12 ETS75873.1 - 4.8 7.2 18.2 0.78 9.8 4.9 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) MscS_porin PF12795.7 ETS75873.1 - 5.9 6.4 48.1 9.2 5.7 32.9 2.8 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Exonuc_VII_S PF02609.16 ETS75873.1 - 8.1 6.6 11.4 11 6.2 0.0 4.1 2 1 1 3 3 3 0 Exonuclease VII small subunit DHR10 PF18595.1 ETS75873.1 - 8.3 6.5 39.6 2.6 8.1 6.1 3.8 1 1 1 3 3 3 0 Designed helical repeat protein 10 domain Isochorismatase PF00857.20 ETS75874.1 - 1.6e-23 83.8 0.0 2.3e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Glycos_transf_1 PF00534.20 ETS75875.1 - 2e-35 121.9 0.0 3.2e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ETS75875.1 - 5.3e-27 94.9 0.0 8.9e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ETS75875.1 - 6.8e-16 58.7 0.0 6.1e-13 49.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ETS75875.1 - 2.4e-10 41.1 0.0 9.9e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 ETS75875.1 - 1.2e-09 38.4 0.0 3.1e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 UDPG_MGDP_dh_N PF03721.14 ETS75876.1 - 1.1e-49 168.5 0.1 4.2e-30 104.7 0.1 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 ETS75876.1 - 3.1e-32 110.6 0.1 9.1e-32 109.1 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 ETS75876.1 - 2.1e-21 76.3 0.0 1.4e-16 60.8 0.0 3.4 3 1 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 ETS75876.1 - 0.0013 19.0 0.0 0.0038 17.5 0.0 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 ETS75876.1 - 0.0062 16.7 0.0 3.6 7.7 0.0 2.7 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 ETS75876.1 - 0.018 14.7 0.0 0.063 12.9 0.0 2.0 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 ETS75876.1 - 0.028 14.3 0.0 0.088 12.7 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 ETS75876.1 - 0.086 13.1 0.1 0.73 10.1 0.0 2.6 3 0 0 3 3 3 0 TrkA-N domain Shikimate_DH PF01488.20 ETS75876.1 - 0.15 12.1 0.0 9.7 6.2 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase CoA_trans PF01144.23 ETS75877.1 - 1.8e-98 328.3 2.4 4.6e-63 212.5 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 ETS75877.1 - 0.00084 19.3 0.1 0.0017 18.3 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 ETS75877.1 - 0.04 12.2 0.1 0.061 11.7 0.1 1.2 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter MFS_1 PF07690.16 ETS75879.1 - 1.3e-36 126.3 23.5 2e-36 125.6 23.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ETS75879.1 - 0.0002 21.1 0.4 0.00055 19.7 0.4 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Zn_clus PF00172.18 ETS75880.1 - 0.013 15.7 11.2 0.025 14.7 11.2 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Inositol_P PF00459.25 ETS75883.1 - 1.2e-35 123.4 1.1 5.4e-35 121.2 1.1 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family DUF2733 PF10813.8 ETS75883.1 - 1 9.2 2.7 0.85 9.5 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) Glyco_hydro_61 PF03443.14 ETS75884.1 - 5.2e-48 163.7 0.1 6.3e-48 163.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glucodextran_B PF09136.10 ETS75884.1 - 0.096 13.1 2.2 1.9 8.9 0.3 2.5 2 0 0 2 2 2 0 Glucodextranase, domain B Glyco_hydro_cc PF11790.8 ETS75885.1 - 1.7e-73 247.1 2.3 2e-73 246.9 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fip1 PF05182.13 ETS75885.1 - 0.0048 16.4 1.9 0.011 15.2 1.9 1.6 1 0 0 1 1 1 1 Fip1 motif Glyco_hydro_64 PF16483.5 ETS75886.1 - 3.4e-88 296.4 0.0 4.1e-88 296.1 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase Thiolase_N PF00108.23 ETS75887.1 - 6.5e-65 219.1 0.8 9.1e-65 218.6 0.8 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ETS75887.1 - 2.7e-39 133.6 0.2 8.5e-39 132.0 0.2 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain BCSC_C PF05420.11 ETS75887.1 - 0.019 14.1 0.2 0.03 13.5 0.2 1.2 1 0 0 1 1 1 0 Cellulose synthase operon protein C C-terminus (BCSC_C) ACP_syn_III PF08545.10 ETS75887.1 - 0.063 13.1 0.5 7.9 6.4 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Amidase PF01425.21 ETS75888.1 - 1.5e-36 126.3 0.0 8.3e-36 123.9 0.0 1.9 1 1 0 1 1 1 1 Amidase AhpC-TSA PF00578.21 ETS75889.1 - 2.6e-36 124.2 0.0 3.5e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ETS75889.1 - 1.5e-12 47.4 0.0 2.1e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ETS75889.1 - 4e-12 45.8 0.0 7.2e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DUF4140 PF13600.6 ETS75890.1 - 1.1e-21 77.1 5.4 1.7e-21 76.5 0.0 2.6 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) DUF4139 PF13598.6 ETS75890.1 - 5.8e-11 42.5 0.0 1.9e-10 40.8 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) HAUS-augmin3 PF14932.6 ETS75890.1 - 1.4 8.4 9.0 0.17 11.4 4.5 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Fungal_trans PF04082.18 ETS75891.1 - 2.1e-09 36.8 0.0 3.4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS75891.1 - 1.6e-05 24.9 7.9 2.8e-05 24.1 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.21 ETS75892.1 - 2.2e-68 231.3 0.4 5.7e-50 170.6 0.0 2.3 2 0 0 2 2 2 2 Amidase Methyltransf_10 PF05971.12 ETS75893.1 - 2.7e-61 207.5 0.0 3.9e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 ETS75893.1 - 1.4e-05 24.7 0.0 2.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 ETS75893.1 - 0.0059 16.4 0.0 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 ETS75893.1 - 0.029 13.8 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 ETS75893.1 - 0.058 14.1 0.0 0.37 11.5 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_18 PF12847.7 ETS75893.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.22 ETS75894.1 - 8e-76 255.6 0.4 1e-75 255.3 0.4 1.1 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.25 ETS75894.1 - 3.6e-20 72.6 0.0 9.3e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 ETS75894.1 - 1.9e-19 70.2 0.0 5.9e-19 68.5 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 ETS75894.1 - 1.4e-14 54.7 0.0 2.5e-13 50.6 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 ETS75894.1 - 7.9e-05 22.9 0.0 0.00018 21.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain RRM_1 PF00076.22 ETS75895.1 - 1.4e-09 37.7 0.1 2.7e-07 30.3 0.1 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 PF05764.13 ETS75895.1 - 0.0029 17.8 14.2 0.0029 17.8 14.2 2.1 2 0 0 2 2 2 1 YL1 nuclear protein Trypan_PARP PF05887.11 ETS75895.1 - 5.6 6.9 9.9 12 5.8 9.9 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Aldedh PF00171.22 ETS75896.1 - 6.5e-132 440.3 0.3 7.2e-132 440.2 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ETS75896.1 - 9.1e-05 22.0 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) LuxC PF05893.14 ETS75896.1 - 0.00019 20.6 0.0 0.00049 19.3 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) MFS_1 PF07690.16 ETS75897.1 - 6.3e-28 97.7 29.1 6.3e-28 97.7 29.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily GHMP_kinases_N PF00288.26 ETS75898.1 - 2.9e-16 59.5 2.5 6.4e-16 58.4 2.5 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ETS75898.1 - 4e-07 30.3 0.0 9.2e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal RPN13_C PF16550.5 ETS75898.1 - 0.11 12.6 0.2 2.1 8.6 0.0 3.0 4 0 0 4 4 4 0 UCH-binding domain Sugar_tr PF00083.24 ETS75900.1 - 1.2e-73 248.5 22.3 1.5e-73 248.2 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS75900.1 - 5.6e-21 74.9 30.6 5.6e-21 74.9 30.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Pantoate_ligase PF02569.15 ETS75901.1 - 4.4e-91 304.8 0.0 5.2e-91 304.5 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase CTP_transf_like PF01467.26 ETS75901.1 - 0.13 12.4 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Cytidylyltransferase-like Glyco_hydro_125 PF06824.11 ETS75902.1 - 3.6e-177 589.4 0.0 4.1e-177 589.2 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Aminotran_1_2 PF00155.21 ETS75903.1 - 1.6e-13 50.6 0.0 5.2e-13 48.9 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ETS75903.1 - 0.044 12.6 0.0 0.074 11.8 0.0 1.3 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase MOZ_SAS PF01853.18 ETS75904.1 - 4.6e-81 270.8 0.3 6.3e-81 270.3 0.3 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 ETS75904.1 - 5.5e-23 80.3 1.5 1.1e-22 79.4 1.5 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 ETS75904.1 - 1.1e-17 63.7 0.3 3e-17 62.2 0.0 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 ETS75904.1 - 0.00083 19.7 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RPA_C PF08784.11 ETS75904.1 - 0.09 13.4 0.4 0.24 12.1 0.0 1.8 2 0 0 2 2 2 0 Replication protein A C terminal Acetyltransf_1 PF00583.25 ETS75904.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family RNase_H2_suC PF08615.11 ETS75905.1 - 1.5e-22 80.3 0.0 1.8e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CMAS PF02353.20 ETS75906.1 - 4.7e-68 229.4 0.0 7.8e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ETS75906.1 - 1.7e-13 51.1 0.0 3.6e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS75906.1 - 1.9e-13 50.9 0.0 4.5e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS75906.1 - 2.5e-09 37.2 0.0 6.2e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS75906.1 - 2e-08 34.1 0.0 5.5e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS75906.1 - 6.7e-06 26.8 0.0 1.5e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 ETS75906.1 - 0.00013 21.2 0.0 0.00021 20.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.19 ETS75906.1 - 0.0008 19.2 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 ETS75906.1 - 0.025 14.3 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 ETS75906.1 - 0.038 13.4 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.12 ETS75906.1 - 0.042 13.6 0.0 0.19 11.5 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF938) GARS_C PF02843.16 ETS75906.1 - 0.052 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain Methyltransf_18 PF12847.7 ETS75906.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GLTP PF08718.11 ETS75907.1 - 1.2e-46 158.7 0.1 2.5e-46 157.6 0.0 1.5 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) Cu-oxidase_2 PF07731.14 ETS75908.1 - 5.2e-21 74.8 7.0 6.4e-20 71.3 1.9 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ETS75908.1 - 4.1e-18 65.5 2.0 6.7e-18 64.8 0.3 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 ETS75908.1 - 1.4e-06 28.5 0.1 5.4e-05 23.4 0.1 2.8 2 0 0 2 2 2 1 Multicopper oxidase Tannase PF07519.11 ETS75909.1 - 2e-107 360.0 1.9 2.6e-107 359.6 1.9 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase NMD3 PF04981.13 ETS75910.1 - 8.2e-82 274.3 1.6 1.1e-81 273.9 1.6 1.2 1 0 0 1 1 1 1 NMD3 family NAD2 PF18782.1 ETS75910.1 - 0.068 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 DZR PF12773.7 ETS75910.1 - 5.6 7.1 11.1 11 6.2 6.5 2.8 1 1 1 2 2 2 0 Double zinc ribbon Tnp_zf-ribbon_2 PF13842.6 ETS75910.1 - 9.3 7.1 10.1 6.4 7.7 0.2 3.1 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon KorB_C PF06613.11 ETS75912.1 - 0.18 11.8 0.0 4.3 7.4 0.0 2.3 2 0 0 2 2 2 0 KorB C-terminal beta-barrel domain HRI1 PF16815.5 ETS75913.1 - 1.6e-30 106.5 0.7 1.9e-30 106.3 0.7 1.0 1 0 0 1 1 1 1 Protein HRI1 p450 PF00067.22 ETS75914.1 - 3.5e-47 161.2 0.0 5.8e-47 160.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 ETS75915.1 - 1.3e-34 119.7 32.5 1.3e-34 119.7 32.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 ETS75915.1 - 0.031 12.6 10.5 0.0069 14.7 4.7 2.5 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Amidohydro_1 PF01979.20 ETS75916.1 - 7.7e-44 150.4 0.0 9.3e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS75916.1 - 1.2e-16 61.3 0.2 1.6e-10 41.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Thioredoxin_2 PF13098.6 ETS75916.1 - 0.014 15.8 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain DUF3604 PF12228.8 ETS75917.1 - 6.2e-10 38.1 0.1 0.00017 20.2 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3604) MFS_1 PF07690.16 ETS75918.1 - 3.9e-28 98.4 9.9 1.8e-27 96.2 9.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 ETS75919.1 - 2.4e-19 69.4 0.6 3.7e-19 68.8 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gpr1_Fun34_YaaH PF01184.19 ETS75920.1 - 3e-58 196.8 23.0 3.6e-58 196.6 23.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family UPF0182 PF03699.13 ETS75920.1 - 0.46 8.5 5.2 0.51 8.4 5.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF2417 PF10329.9 ETS75920.1 - 1.5 8.1 7.8 2.7 7.4 7.8 1.4 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Ank_2 PF12796.7 ETS75921.1 - 8e-54 180.2 2.5 6e-12 46.0 0.0 6.4 3 1 3 6 6 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS75921.1 - 9.2e-48 160.0 6.0 8.3e-10 39.0 0.0 9.1 2 1 8 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS75921.1 - 5.6e-41 133.8 7.1 0.0009 19.5 0.0 12.5 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 ETS75921.1 - 4.3e-36 122.5 11.8 3.3e-05 24.1 0.0 10.4 2 2 8 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 ETS75921.1 - 3e-25 87.5 23.0 0.0023 18.3 0.3 12.9 12 1 0 12 12 11 6 Ankyrin repeat NACHT PF05729.12 ETS75921.1 - 9.4e-05 22.4 0.0 0.0003 20.8 0.0 1.9 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.14 ETS75921.1 - 0.00013 21.5 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) KAP_NTPase PF07693.14 ETS75921.1 - 0.00035 19.9 0.0 0.76 9.0 0.0 2.7 2 1 1 3 3 3 2 KAP family P-loop domain AAA_22 PF13401.6 ETS75921.1 - 0.0008 19.7 0.0 0.021 15.1 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS75921.1 - 0.012 15.9 0.0 0.057 13.8 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain Cutinase PF01083.22 ETS75921.1 - 0.022 14.7 0.0 0.068 13.1 0.0 1.7 2 0 0 2 2 2 0 Cutinase AAA PF00004.29 ETS75921.1 - 0.023 15.1 0.0 0.063 13.7 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Abhydrolase_6 PF12697.7 ETS75921.1 - 0.035 14.7 0.2 0.19 12.3 0.0 2.3 3 0 0 3 3 2 0 Alpha/beta hydrolase family Ploopntkinase3 PF18751.1 ETS75921.1 - 0.084 12.8 0.1 4.8 7.1 0.0 3.2 3 1 1 4 4 4 0 P-loop Nucleotide Kinase3 PGAP1 PF07819.13 ETS75921.1 - 0.15 11.8 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein AAA_30 PF13604.6 ETS75921.1 - 0.19 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 ETS75922.1 - 4.6e-48 164.1 0.0 6.3e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS75925.1 - 9.6e-53 179.6 0.0 1.2e-52 179.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GST_N_3 PF13417.6 ETS75926.1 - 1.8e-14 53.9 0.0 5.4e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ETS75926.1 - 3.3e-12 46.5 0.0 7.9e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ETS75926.1 - 1.1e-11 44.9 0.0 1.8e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ETS75926.1 - 3e-11 43.4 0.0 4.6e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ETS75926.1 - 2.5e-08 34.0 0.0 5e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ETS75926.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Cys_Met_Meta_PP PF01053.20 ETS75927.1 - 4.8e-52 176.8 0.0 3.2e-51 174.0 0.0 2.2 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Fungal_trans PF04082.18 ETS75928.1 - 0.00031 19.9 4.6 0.0007 18.7 4.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ring_hydroxyl_A PF00848.19 ETS75929.1 - 4.1e-09 36.7 0.0 5.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 ETS75930.1 - 3e-13 49.5 0.0 4.9e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 ETS75930.1 - 1.9e-10 41.0 2.6 4.4e-10 39.9 2.0 1.9 1 1 1 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) MFS_1 PF07690.16 ETS75931.1 - 2.7e-18 66.0 34.1 2.7e-18 66.0 34.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DAO PF01266.24 ETS75932.1 - 1.7e-32 113.4 1.5 2e-32 113.2 1.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ETS75932.1 - 0.0082 15.3 0.4 0.012 14.7 0.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 ETS75932.1 - 0.018 14.3 2.5 0.28 10.4 0.2 2.1 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ETS75932.1 - 0.033 13.5 1.4 0.044 13.1 0.7 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 ETS75932.1 - 0.046 13.6 1.1 0.74 9.7 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 ETS75932.1 - 0.053 13.7 0.3 0.64 10.3 0.2 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS75932.1 - 0.51 9.3 7.1 0.89 8.6 0.3 2.1 1 1 1 2 2 2 0 FAD binding domain DAO PF01266.24 ETS75933.1 - 1.7e-07 31.1 0.0 2e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF3433 PF11915.8 ETS75934.1 - 4.7e-21 75.1 19.3 3.5e-12 46.6 1.7 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) DUF4605 PF15378.6 ETS75934.1 - 0.086 12.7 1.7 5.9 6.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) LysM PF01476.20 ETS75935.1 - 9.8e-07 28.7 0.1 0.083 13.0 0.0 3.8 4 0 0 4 4 4 2 LysM domain DUF1153 PF06627.11 ETS75935.1 - 0.063 13.4 0.3 3.3 7.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1153) Croc_4 PF17691.1 ETS75935.1 - 0.37 10.8 5.5 0.3 11.1 0.4 2.7 3 0 0 3 3 3 0 Contingent replication of cDNA 4 SET PF00856.28 ETS75936.1 - 8.6e-08 32.8 0.1 1.5e-07 31.9 0.1 1.8 1 1 0 1 1 1 1 SET domain MFS_1 PF07690.16 ETS75937.1 - 1.2e-11 44.2 38.7 2e-11 43.4 38.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ETS75937.1 - 2.4e-05 24.1 7.4 7.3e-05 22.5 7.4 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Acetyltransf_10 PF13673.7 ETS75938.1 - 1.5e-05 25.0 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS75938.1 - 3.4e-05 24.2 0.0 5.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS75938.1 - 6.3e-05 23.2 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ETS75938.1 - 0.058 13.5 0.0 8.3 6.5 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GSH-S_ATP PF02955.16 ETS75939.1 - 0.00031 20.2 0.0 0.00047 19.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain DUF3176 PF11374.8 ETS75940.1 - 0.081 13.1 0.0 0.18 12.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3176) Aldedh PF00171.22 ETS75942.1 - 2.5e-105 352.7 2.2 1.4e-102 343.6 2.2 2.9 1 1 0 1 1 1 1 Aldehyde dehydrogenase family ketoacyl-synt PF00109.26 ETS75944.1 - 1.3e-56 192.0 0.0 2.9e-56 190.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 ETS75944.1 - 2.1e-56 191.8 0.0 3.4e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 ETS75944.1 - 7.3e-56 188.9 0.2 1.6e-55 187.8 0.2 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 ETS75944.1 - 5.6e-49 167.0 0.0 9.4e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 ETS75944.1 - 7e-30 103.5 0.2 2.2e-29 101.9 0.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ETS75944.1 - 2.9e-20 72.8 0.0 6.3e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 ETS75944.1 - 9e-19 68.1 0.0 3.6e-18 66.1 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 ETS75944.1 - 3.7e-14 53.9 0.0 3.3e-12 47.6 0.0 3.2 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ETS75944.1 - 1e-13 51.4 0.2 3.4e-13 49.7 0.2 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 ETS75944.1 - 1.5e-12 47.7 0.0 4.1e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS75944.1 - 5e-11 43.1 0.0 1.8e-10 41.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS75944.1 - 8.9e-11 42.4 0.0 3.5e-10 40.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS75944.1 - 5.5e-10 39.2 0.0 4.2e-09 36.4 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain PP-binding PF00550.25 ETS75944.1 - 2.9e-09 37.2 0.1 6.4e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 ETS75944.1 - 4.2e-07 29.8 0.2 1.2e-06 28.3 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 ETS75944.1 - 5.9e-06 25.9 0.4 1.5e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase DREV PF05219.12 ETS75944.1 - 0.00059 19.0 0.0 0.0013 17.9 0.0 1.5 1 0 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.18 ETS75944.1 - 0.025 13.9 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 ETS75944.1 - 0.095 11.7 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_33 PF10017.9 ETS75944.1 - 0.18 10.9 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent TauD PF02668.16 ETS75945.1 - 3.6e-62 210.6 0.4 4.8e-62 210.2 0.4 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 ETS75947.1 - 3.9e-49 167.5 20.2 6.8e-49 166.7 19.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS75947.1 - 8.4e-06 24.9 8.8 8.4e-06 24.9 8.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Syntaxin-18_N PF10496.9 ETS75948.1 - 7.7e-10 38.9 0.1 7.7e-10 38.9 0.1 3.1 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus DprA_WH PF17782.1 ETS75948.1 - 0.062 13.4 0.9 0.17 12.0 0.1 2.2 2 0 0 2 2 2 0 DprA winged helix domain Phage_int_SAM_2 PF12834.7 ETS75948.1 - 0.54 11.0 4.7 1.5 9.5 0.1 3.4 3 1 1 4 4 4 0 Phage integrase, N-terminal Aminotran_1_2 PF00155.21 ETS75949.1 - 3.1e-86 289.8 0.0 3.7e-86 289.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1233 PF06806.12 ETS75949.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Putative excisionase (DUF1233) Macro_2 PF14519.6 ETS75950.1 - 0.0049 16.2 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 Macro-like domain Macro PF01661.21 ETS75950.1 - 0.07 13.2 0.0 4.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Macro domain F-box PF00646.33 ETS75951.1 - 6.2e-05 22.8 0.8 0.00017 21.4 0.8 1.7 1 0 0 1 1 1 1 F-box domain Lipase_GDSL_2 PF13472.6 ETS75952.1 - 2e-15 57.6 0.1 2.8e-15 57.2 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS75952.1 - 7.3e-13 48.9 0.1 9.1e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 ETS75952.1 - 8.6e-05 22.7 0.0 0.00012 22.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 ETS75952.1 - 0.00013 21.2 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 OSK domain Asp PF00026.23 ETS75953.1 - 2.1e-67 227.8 7.7 1.4e-49 169.2 2.2 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS75953.1 - 5.6e-15 56.0 0.2 1.8e-14 54.3 0.2 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ETS75953.1 - 6.8e-05 23.4 0.4 0.51 11.0 0.0 3.4 3 0 0 3 3 3 2 Aspartyl protease ADH_zinc_N PF00107.26 ETS75954.1 - 1.4e-22 80.0 0.1 3.3e-22 78.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS75954.1 - 1.6e-20 73.0 0.7 2.6e-20 72.3 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 ETS75954.1 - 3.5e-05 23.2 2.2 5.8e-05 22.5 2.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 ETS75954.1 - 0.013 14.6 0.2 0.016 14.3 0.2 1.1 1 0 0 1 1 1 0 FAD binding domain ADH_zinc_N_2 PF13602.6 ETS75954.1 - 0.035 15.2 0.0 0.056 14.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ETS75954.1 - 0.14 11.5 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ABC_tran PF00005.27 ETS75955.1 - 4.1e-47 160.1 1.1 1.7e-23 83.6 0.0 3.8 3 1 0 3 3 2 2 ABC transporter 4HB PF17947.1 ETS75955.1 - 2.9e-29 101.0 0.6 1.7e-28 98.4 0.0 2.8 2 1 0 2 2 2 1 Four helical bundle domain AAA_21 PF13304.6 ETS75955.1 - 2.3e-17 63.8 0.1 0.0018 18.2 0.0 4.9 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETS75955.1 - 5.2e-17 62.0 0.9 2.6e-05 23.8 0.0 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ETS75955.1 - 9e-09 35.0 0.0 0.0055 16.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 ETS75955.1 - 2.8e-08 34.5 0.2 7.3e-05 23.4 0.1 3.8 4 0 0 4 4 2 2 AAA domain RsgA_GTPase PF03193.16 ETS75955.1 - 1e-07 32.0 0.1 0.0012 18.8 0.0 3.1 2 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ETS75955.1 - 2.6e-07 31.0 0.0 0.0052 17.1 0.0 3.4 4 0 0 4 4 3 2 AAA domain Dynamin_N PF00350.23 ETS75955.1 - 3.2e-07 30.6 0.3 0.00028 21.0 0.0 3.0 3 0 0 3 3 2 1 Dynamin family MMR_HSR1 PF01926.23 ETS75955.1 - 3.5e-07 30.3 0.0 0.0021 18.1 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 ETS75955.1 - 1.5e-06 28.2 0.2 0.018 14.8 0.0 3.4 3 1 1 4 4 3 2 AAA ATPase domain AAA_28 PF13521.6 ETS75955.1 - 2.1e-06 28.1 0.0 0.033 14.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ETS75955.1 - 6e-06 26.8 0.1 0.09 13.3 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 ETS75955.1 - 1.6e-05 25.3 0.0 0.26 11.7 0.0 4.0 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ETS75955.1 - 1.9e-05 24.9 0.0 0.33 11.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ETS75955.1 - 2.9e-05 24.5 0.1 0.44 10.9 0.0 3.5 4 0 0 4 4 3 2 AAA ATPase domain G-alpha PF00503.20 ETS75955.1 - 3.7e-05 23.0 0.2 0.2 10.8 0.0 3.1 3 0 0 3 3 3 2 G-protein alpha subunit PduV-EutP PF10662.9 ETS75955.1 - 4.5e-05 23.2 0.1 0.051 13.3 0.0 3.1 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 ETS75955.1 - 8.2e-05 23.0 0.0 0.75 10.2 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_27 PF13514.6 ETS75955.1 - 0.00016 21.3 0.0 0.14 11.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 ETS75955.1 - 0.00023 20.3 0.5 0.73 8.8 0.0 2.8 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 ETS75955.1 - 0.0005 20.0 0.0 0.15 12.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 ETS75955.1 - 0.00055 20.1 0.2 1 9.4 0.1 3.6 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_14 PF13173.6 ETS75955.1 - 0.00079 19.5 0.1 2.3 8.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain ParcG PF10274.9 ETS75955.1 - 0.0008 19.6 1.8 1.4 9.0 0.1 3.1 1 1 2 3 3 3 1 Parkin co-regulated protein AAA_24 PF13479.6 ETS75955.1 - 0.00084 19.1 0.0 1.5 8.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain DRIM PF07539.12 ETS75955.1 - 0.0014 17.0 1.7 0.18 10.1 0.1 2.2 2 0 0 2 2 2 2 Down-regulated in metastasis AAA_30 PF13604.6 ETS75955.1 - 0.0016 18.2 0.0 2.9 7.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 ETS75955.1 - 0.0016 18.1 0.1 4.7 6.8 0.0 3.7 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 ETS75955.1 - 0.0018 18.2 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain Roc PF08477.13 ETS75955.1 - 0.0026 18.0 0.2 8.4 6.6 0.0 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 ETS75955.1 - 0.0032 16.7 0.2 0.17 11.1 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 ETS75955.1 - 0.0043 17.0 0.2 1.3 8.9 0.0 3.1 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea PRK PF00485.18 ETS75955.1 - 0.0079 16.0 0.0 0.45 10.2 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.17 ETS75955.1 - 0.0082 15.9 0.0 6.8 6.4 0.0 3.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 ETS75955.1 - 0.0083 15.4 1.1 2.6 7.3 0.0 3.1 3 0 0 3 3 3 1 Septin SbcCD_C PF13558.6 ETS75955.1 - 0.0085 16.3 0.0 2.2 8.6 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit CLP1_P PF16575.5 ETS75955.1 - 0.0094 15.8 0.9 0.4 10.4 0.0 3.0 4 0 0 4 4 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_7 PF12775.7 ETS75955.1 - 0.017 14.7 0.0 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region MukB PF04310.12 ETS75955.1 - 0.019 14.8 0.1 3.6 7.3 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal Cytidylate_kin PF02224.18 ETS75955.1 - 0.026 14.2 0.0 7.3 6.3 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase Mg_chelatase PF01078.21 ETS75955.1 - 0.027 13.8 0.0 4.2 6.7 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 ETS75955.1 - 0.036 13.8 0.0 9.6 5.9 0.0 2.9 2 0 0 2 2 2 0 IstB-like ATP binding protein HEAT PF02985.22 ETS75955.1 - 0.04 14.2 1.1 63 4.2 0.0 4.7 5 0 0 5 5 3 0 HEAT repeat AAA_25 PF13481.6 ETS75955.1 - 0.048 13.2 0.0 6.5 6.3 0.0 3.2 4 0 0 4 4 2 0 AAA domain NTPase_1 PF03266.15 ETS75955.1 - 0.076 12.9 0.1 19 5.2 0.1 2.8 2 0 0 2 2 2 0 NTPase Ploopntkinase3 PF18751.1 ETS75955.1 - 0.1 12.5 0.0 19 5.1 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ATP-synt_ab PF00006.25 ETS75955.1 - 0.11 12.2 0.0 7.1 6.2 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Transglut_prok PF09017.10 ETS75955.1 - 0.11 11.8 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Microbial transglutaminase GTP_EFTU PF00009.27 ETS75955.1 - 0.11 12.0 0.1 11 5.5 0.0 2.9 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain DAP3 PF10236.9 ETS75955.1 - 0.39 9.8 5.5 1.4 8.1 1.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 SIR2 PF02146.17 ETS75957.1 - 8.8e-25 87.7 0.8 1.6e-11 44.4 0.0 3.5 2 1 0 3 3 3 3 Sir2 family CTP_transf_1 PF01148.20 ETS75958.1 - 1.1e-79 267.9 24.1 1.4e-79 267.6 24.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.8 ETS75959.1 - 1.5e-38 131.9 0.1 2.8e-38 131.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) PKcGMP_CC PF16808.5 ETS75959.1 - 0.046 13.6 5.8 0.028 14.3 2.7 2.2 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FAM76 PF16046.5 ETS75959.1 - 0.081 12.3 7.4 0.13 11.6 7.4 1.2 1 0 0 1 1 1 0 FAM76 protein Lsr2 PF11774.8 ETS75959.1 - 7.4 6.8 12.3 1.1 9.5 4.5 2.6 2 0 0 2 2 2 0 Lsr2 PRIMA1 PF16101.5 ETS75960.1 - 0.0048 16.9 0.8 0.0072 16.4 0.8 1.2 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Herpes_gE PF02480.16 ETS75960.1 - 0.064 12.0 0.0 0.078 11.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DEC-1_N PF04625.13 ETS75960.1 - 0.51 9.3 2.6 0.6 9.1 2.6 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Glyco_hydro_16 PF00722.21 ETS75961.1 - 2.6e-40 137.7 7.5 2.6e-40 137.7 7.5 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Sporozoite_P67 PF05642.11 ETS75961.1 - 0.08 11.0 7.6 0.091 10.8 7.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TPR_12 PF13424.6 ETS75962.1 - 1.4e-05 25.3 0.0 0.25 11.7 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF5092 PF17010.5 ETS75962.1 - 0.058 13.3 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5092) TPR_19 PF14559.6 ETS75962.1 - 0.1 13.1 0.1 0.3 11.6 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 ETS75962.1 - 0.59 10.5 3.4 2.1 8.7 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 ETS75962.1 - 0.62 10.0 4.3 1.9 8.5 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Clr5 PF14420.6 ETS75963.1 - 8.7e-11 41.9 1.5 1.1e-10 41.6 1.5 1.1 1 0 0 1 1 1 1 Clr5 domain PD40 PF07676.12 ETS75964.1 - 1.1e-36 124.0 23.0 6.1e-07 29.2 1.8 9.2 9 0 0 9 9 9 8 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 ETS75964.1 - 9.6e-09 34.4 5.2 0.081 11.7 0.3 6.5 5 1 1 6 6 6 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3748 PF12566.8 ETS75964.1 - 0.0034 17.3 0.6 45 4.0 0.0 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3748) WD40 PF00400.32 ETS75964.1 - 0.014 16.2 10.9 17 6.4 0.0 6.0 7 0 0 7 7 7 0 WD domain, G-beta repeat DUF1513 PF07433.11 ETS75964.1 - 0.058 12.5 0.2 28 3.7 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Glyco_hydro_30C PF17189.4 ETS75964.1 - 0.37 11.0 5.6 0.49 10.7 0.7 3.5 3 0 0 3 3 3 0 Glycosyl hydrolase family 30 beta sandwich domain FAD_binding_4 PF01565.23 ETS75965.1 - 7.5e-22 77.6 0.7 2.2e-21 76.1 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 ETS75965.1 - 0.08 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like Esterase_phd PF10503.9 ETS75967.1 - 1.4e-05 24.7 0.0 3.9e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ETS75967.1 - 0.00067 19.2 0.0 0.0017 17.9 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 ETS75967.1 - 0.0011 18.6 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.12 ETS75967.1 - 0.0037 16.0 0.0 0.014 14.1 0.0 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 ETS75967.1 - 0.13 12.0 0.0 0.49 10.1 0.0 1.8 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase tRNA-synt_1c PF00749.21 ETS75968.1 - 2.1e-99 332.4 0.0 2.9e-99 331.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 ETS75968.1 - 4.4e-32 111.3 0.0 1.5e-31 109.6 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Fructosamin_kin PF03881.14 ETS75969.1 - 4.5e-30 104.8 0.0 5.9e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 ETS75969.1 - 4e-07 30.2 0.0 5.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ETS75969.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase BNR_2 PF13088.6 ETS75970.1 - 1.5e-07 31.0 3.0 0.008 15.5 0.3 4.0 1 1 4 5 5 5 5 BNR repeat-like domain BNR PF02012.20 ETS75970.1 - 0.16 12.0 18.7 0.38 10.9 0.4 5.4 5 0 0 5 5 5 0 BNR/Asp-box repeat Pro-kuma_activ PF09286.11 ETS75971.1 - 1.7e-35 122.4 0.2 1e-33 116.7 0.1 2.3 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ETS75971.1 - 0.00021 20.6 4.8 0.00036 19.9 4.8 1.3 1 0 0 1 1 1 1 Subtilase family GMC_oxred_N PF00732.19 ETS75972.1 - 8.7e-60 202.6 0.0 1.2e-59 202.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS75972.1 - 3.4e-32 111.9 0.0 5.7e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ETS75972.1 - 0.003 16.7 0.1 0.006 15.7 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ETS75972.1 - 0.0051 17.0 0.4 0.019 15.2 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS75972.1 - 0.015 14.9 0.7 0.04 13.5 0.2 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS75972.1 - 0.017 14.4 0.1 0.3 10.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPR_MLP1_2 PF07926.12 ETS75973.1 - 0.0028 17.7 2.2 0.0051 16.9 2.2 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 ETS75973.1 - 0.0056 16.9 0.9 0.015 15.5 0.0 1.9 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 ETS75973.1 - 0.015 14.7 1.2 0.021 14.1 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PTRF_SDPR PF15237.6 ETS75973.1 - 0.034 13.8 0.1 0.065 12.8 0.1 1.5 1 0 0 1 1 1 0 PTRF/SDPR family Nsp1_C PF05064.13 ETS75973.1 - 0.039 13.8 0.4 0.063 13.1 0.4 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region UvrD_C PF13361.6 ETS75973.1 - 0.048 13.0 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain XhlA PF10779.9 ETS75973.1 - 0.065 13.4 0.4 0.11 12.7 0.4 1.4 1 0 0 1 1 1 0 Haemolysin XhlA MCPsignal PF00015.21 ETS75973.1 - 0.068 13.0 0.3 0.1 12.4 0.3 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain GCP_N_terminal PF17681.1 ETS75973.1 - 0.078 12.6 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal FUSC PF04632.12 ETS75973.1 - 0.78 8.2 4.8 1.1 7.7 4.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family HrpB7 PF09486.10 ETS75973.1 - 0.97 9.8 8.8 0.1 13.0 2.7 2.1 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) MFS_1 PF07690.16 ETS75975.1 - 1.7e-37 129.2 44.2 3.9e-37 128.0 38.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS75975.1 - 3.3e-09 36.1 13.1 3.3e-09 36.1 13.1 3.3 2 2 3 5 5 5 1 Sugar (and other) transporter LOR PF04525.12 ETS75976.1 - 3.7e-06 26.7 0.4 4.2e-05 23.2 0.4 2.0 1 1 0 1 1 1 1 LURP-one-related Top6b_C PF18000.1 ETS75976.1 - 0.082 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain DUF826 PF05696.11 ETS75977.1 - 0.1 12.7 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF826) Phage_Gp23 PF10669.9 ETS75978.1 - 0.064 13.6 4.3 0.099 13.0 4.3 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) SpoVR PF04293.13 ETS75978.1 - 0.068 11.9 0.5 0.083 11.6 0.5 1.1 1 0 0 1 1 1 0 SpoVR like protein UPF0542 PF15086.6 ETS75978.1 - 1.2 9.1 5.5 6.1 6.9 5.5 2.1 1 1 0 1 1 1 0 Uncharacterised protein family UPF0542 Pyridoxal_deC PF00282.19 ETS75979.1 - 4.6e-108 361.3 0.0 5.5e-108 361.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain LysM PF01476.20 ETS75980.1 - 1.5e-17 63.3 7.5 1.4e-07 31.5 0.1 5.9 6 0 0 6 6 6 4 LysM domain DUF1153 PF06627.11 ETS75980.1 - 0.03 14.4 0.0 0.83 9.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1153) Glyco_hydro_18 PF00704.28 ETS75981.1 - 1.4e-72 245.1 2.2 2.5e-72 244.2 2.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ETS75981.1 - 5.3e-12 46.0 16.1 5.3e-12 46.0 16.1 4.9 5 0 0 5 5 5 2 Chitin recognition protein Hairy_orange PF07527.13 ETS75982.1 - 0.043 14.0 0.1 0.49 10.6 0.0 2.4 2 0 0 2 2 2 0 Hairy Orange EthD PF07110.11 ETS75983.1 - 5.1e-12 46.8 0.1 6.6e-12 46.4 0.1 1.1 1 0 0 1 1 1 1 EthD domain ketoacyl-synt PF00109.26 ETS75984.1 - 6.4e-81 271.6 0.0 1.2e-80 270.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 ETS75984.1 - 1.4e-63 215.3 0.1 2.4e-63 214.6 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 ETS75984.1 - 2.2e-58 197.1 0.0 7.1e-58 195.5 0.0 1.9 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 ETS75984.1 - 1.9e-39 134.4 1.5 7.7e-39 132.4 1.1 2.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ETS75984.1 - 6.3e-12 45.9 0.0 1.5e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 ETS75984.1 - 1.2e-11 44.5 0.1 3.2e-11 43.0 0.1 1.7 1 1 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 ETS75984.1 - 3.2e-10 40.2 0.1 9.2e-10 38.7 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 ETS75984.1 - 0.00014 21.4 0.0 0.0014 18.1 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 ETS75984.1 - 0.00019 20.9 0.3 0.00086 18.7 0.4 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain HLH PF00010.26 ETS75985.1 - 9.9e-13 47.8 0.1 1.9e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DivIC PF04977.15 ETS75985.1 - 0.32 10.8 2.4 0.33 10.8 0.2 2.0 2 0 0 2 2 2 0 Septum formation initiator Mg_trans_NIPA PF05653.14 ETS75986.1 - 3.7e-62 210.1 10.0 4.2e-60 203.3 6.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 ETS75986.1 - 0.00035 20.8 13.7 0.0011 19.1 3.5 3.9 3 1 1 4 4 4 2 EamA-like transporter family Neur_chan_memb PF02932.16 ETS75986.1 - 0.036 14.1 0.0 0.91 9.5 0.0 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Iron_permease PF04120.12 ETS75986.1 - 0.094 12.5 0.3 0.46 10.3 0.0 2.3 2 0 0 2 2 2 0 Low affinity iron permease TssN PF17555.2 ETS75986.1 - 0.38 10.1 7.8 0.62 9.4 7.8 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN Transgly_assoc PF04226.13 ETS75986.1 - 1.5 9.2 7.8 5.4 7.3 2.5 3.2 2 0 0 2 2 2 0 Transglycosylase associated protein DUF1461 PF07314.11 ETS75986.1 - 1.7 8.5 5.3 0.64 9.9 0.7 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1461) TMEM138 PF14935.6 ETS75986.1 - 7 7.3 8.5 3.8 8.2 2.4 2.4 1 1 1 2 2 2 0 Transmembrane protein 138 WD40 PF00400.32 ETS75987.1 - 3.8e-12 46.5 17.7 0.0077 17.1 0.7 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS75987.1 - 2.4e-05 24.5 0.0 1.2 9.5 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain MraZ PF02381.18 ETS75987.1 - 0.12 12.4 0.0 24 5.0 0.0 2.5 2 0 0 2 2 2 0 MraZ protein, putative antitoxin-like AF-4 PF05110.13 ETS75987.1 - 0.17 9.9 9.3 0.24 9.5 9.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Cwf_Cwc_15 PF04889.12 ETS75987.1 - 0.36 10.5 8.8 0.68 9.6 8.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 ETS75987.1 - 3.3 6.9 6.4 5.3 6.3 6.4 1.2 1 0 0 1 1 1 0 NOA36 protein SNF2_N PF00176.23 ETS75988.1 - 4.7e-72 242.6 0.8 4.7e-72 242.6 0.8 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 ETS75988.1 - 1.5e-22 79.5 0.4 4.6e-22 77.9 0.4 1.9 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 ETS75988.1 - 3.7e-21 75.6 1.8 1.9e-18 66.9 0.0 4.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 ETS75988.1 - 1.1e-16 60.8 15.3 1.1e-16 60.8 15.3 5.3 7 0 0 7 7 7 1 HSA SnAC PF14619.6 ETS75988.1 - 1e-13 51.7 0.3 1e-13 51.7 0.3 3.9 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 ETS75988.1 - 1e-10 41.9 0.1 1e-10 41.9 0.1 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit QLQ PF08880.11 ETS75988.1 - 6.5e-10 38.6 10.2 1.8e-09 37.2 10.2 1.8 1 0 0 1 1 1 1 QLQ RBR PF17208.3 ETS75988.1 - 0.023 15.4 9.1 0.025 15.3 6.6 2.4 1 1 0 1 1 1 0 RNA binding Region MFS_1 PF07690.16 ETS75990.1 - 4.1e-24 85.2 37.0 5.4e-24 84.8 37.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2985 PF11204.8 ETS75990.1 - 0.076 13.2 0.1 0.076 13.2 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2985) CoA_transf_3 PF02515.17 ETS75991.1 - 2.1e-110 369.3 0.0 2.5e-110 369.1 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Acyl-CoA_dh_1 PF00441.24 ETS75992.1 - 9.4e-31 107.0 4.7 1.7e-30 106.2 4.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ETS75992.1 - 1.1e-19 70.4 0.0 2.5e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ETS75992.1 - 2.1e-18 67.0 0.1 6.2e-18 65.5 0.1 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ETS75992.1 - 7.6e-14 52.1 7.1 1.1e-13 51.6 4.9 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Carboxyl_trans PF01039.22 ETS75993.1 - 2.4e-76 257.4 0.0 2.5e-75 254.0 0.0 2.0 1 1 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 ETS75994.1 - 7.2e-54 182.5 0.0 1e-53 182.0 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ETS75994.1 - 2.2e-30 105.5 0.0 5.8e-30 104.1 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ETS75994.1 - 1.6e-29 102.2 0.0 3.2e-28 98.0 0.0 2.7 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ETS75994.1 - 5.1e-13 48.6 0.1 1.3e-12 47.3 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ETS75994.1 - 2.1e-07 30.6 2.0 6.2e-07 29.1 0.5 2.5 2 1 0 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 ETS75994.1 - 1.3e-05 24.8 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus DUF2118 PF09891.9 ETS75994.1 - 0.00074 19.5 0.0 0.0021 18.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) RnfC_N PF13375.6 ETS75994.1 - 0.00097 19.1 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain ATPgrasp_ST PF14397.6 ETS75994.1 - 0.0023 17.2 0.0 0.0044 16.3 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 ETS75994.1 - 0.0056 16.7 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain QRPTase_N PF02749.16 ETS75994.1 - 0.017 15.2 0.2 6.2 6.9 0.0 3.5 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain HlyD_3 PF13437.6 ETS75994.1 - 0.13 13.0 0.3 4.6 8.0 0.2 2.6 1 1 1 2 2 2 0 HlyD family secretion protein Sad1_UNC PF07738.13 ETS75995.1 - 1.9e-33 115.3 0.0 4.1e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 ETS75995.1 - 0.0038 17.3 0.0 0.0093 16.1 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain Macoilin PF09726.9 ETS75995.1 - 0.99 7.9 8.1 2.1 6.8 8.1 1.4 1 0 0 1 1 1 0 Macoilin family RRM_2 PF04059.12 ETS75996.1 - 3.8e-38 129.6 1.0 6.6e-38 128.8 1.0 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 ETS75996.1 - 0.00011 21.9 0.1 0.074 12.9 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec15 PF04091.12 ETS75997.1 - 7.4e-114 380.4 1.9 7.4e-114 380.4 1.9 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like DUF2451 PF10474.9 ETS75997.1 - 0.00012 22.0 1.4 0.00028 20.8 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) MutL_C PF08676.11 ETS75997.1 - 0.0026 17.5 0.2 0.013 15.2 0.0 2.3 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DUF4201 PF13870.6 ETS75997.1 - 0.0057 16.4 5.2 0.016 14.9 5.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) DUF3510 PF12022.8 ETS75997.1 - 0.0096 16.3 4.3 2.5 8.5 0.0 3.5 2 1 1 3 3 3 2 Domain of unknown function (DUF3510) DUF16 PF01519.16 ETS75997.1 - 0.048 14.1 1.2 0.3 11.6 1.2 2.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 COG5 PF10392.9 ETS75997.1 - 0.39 10.9 6.7 0.26 11.4 2.4 2.8 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DASH_Duo1 PF08651.10 ETS75997.1 - 0.71 9.7 4.1 0.95 9.3 1.2 2.8 3 0 0 3 3 3 0 DASH complex subunit Duo1 Sec8_exocyst PF04048.14 ETS75997.1 - 2.2 8.2 9.5 0.41 10.5 2.4 3.1 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain ApoLp-III PF07464.11 ETS75997.1 - 4.7 7.3 11.4 1.4 9.0 4.4 3.1 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Seryl_tRNA_N PF02403.22 ETS75997.1 - 8.3 6.7 9.2 71 3.7 0.0 3.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CBFD_NFYB_HMF PF00808.23 ETS75998.1 - 2.6e-19 69.3 0.5 3.7e-19 68.8 0.5 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ETS75998.1 - 7.2e-15 55.5 0.2 1.1e-14 54.9 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 ETS75998.1 - 0.045 14.1 0.1 0.071 13.4 0.1 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Fcf2 PF08698.11 ETS75999.1 - 7.4e-36 122.4 0.6 7.4e-36 122.4 0.6 2.1 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing Phage_holin_3_3 PF16083.5 ETS76000.1 - 0.0014 18.7 1.9 5.3 7.2 0.1 3.3 3 0 0 3 3 3 2 LydA holin phage, holin superfamily III RRM_1 PF00076.22 ETS76001.1 - 1.7e-10 40.6 0.0 3.2e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mitofilin PF09731.9 ETS76001.1 - 0.057 12.3 15.8 0.073 11.9 15.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein UPF0242 PF06785.11 ETS76001.1 - 9.2 6.3 7.9 14 5.7 7.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus COX2_TM PF02790.15 ETS76002.1 - 0.034 14.3 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain CCB1 PF12046.8 ETS76002.1 - 0.1 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B tRNA_synthFbeta PF17759.1 ETS76003.1 - 3.6e-45 154.0 0.0 5.3e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 ETS76003.1 - 1.1e-27 96.1 0.1 3.2e-23 81.8 0.0 3.5 3 1 0 3 3 3 2 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 ETS76003.1 - 2.7e-27 95.6 0.0 5e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 ETS76003.1 - 4.8e-15 55.6 0.0 3.5e-13 49.6 0.0 2.7 2 0 0 2 2 2 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 ETS76003.1 - 0.0095 15.4 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Herpes_V23 PF01802.17 ETS76003.1 - 0.086 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein FliW PF02623.15 ETS76003.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 FliW protein HEAT PF02985.22 ETS76004.1 - 2.6e-38 126.7 11.7 0.028 14.7 0.1 13.2 14 0 0 14 14 14 9 HEAT repeat HEAT_2 PF13646.6 ETS76004.1 - 1.6e-34 118.1 7.2 4.8e-10 39.7 0.0 8.2 3 3 5 8 8 8 8 HEAT repeats Cnd1 PF12717.7 ETS76004.1 - 3.1e-10 40.3 15.5 0.0012 19.0 0.1 6.3 4 2 3 7 7 7 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ETS76004.1 - 9.9e-10 38.9 6.4 0.029 15.0 0.1 7.4 5 2 4 9 9 9 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 ETS76004.1 - 1.7e-09 37.9 5.2 0.11 13.0 0.0 8.0 10 1 1 11 11 10 2 HEAT-like repeat RTP1_C1 PF10363.9 ETS76004.1 - 3.6e-06 27.1 7.1 0.56 10.4 0.1 5.3 4 1 1 6 6 6 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 ETS76004.1 - 1.6e-05 24.6 1.6 0.33 10.5 0.0 4.3 2 2 2 4 4 4 2 CLASP N terminal Adaptin_N PF01602.20 ETS76004.1 - 3.6e-05 22.5 10.0 0.2 10.1 0.4 4.7 3 2 0 4 4 4 2 Adaptin N terminal region Proteasom_PSMB PF10508.9 ETS76004.1 - 0.032 12.7 4.2 0.36 9.3 0.0 2.4 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit M11L PF11099.8 ETS76004.1 - 0.071 13.4 0.2 16 5.7 0.0 3.3 2 1 0 3 3 3 0 Apoptosis regulator M11L like Ecm29 PF13001.7 ETS76004.1 - 6.6 5.3 7.8 7.6 5.1 0.0 3.6 5 1 1 6 6 6 0 Proteasome stabiliser Methyltransf_31 PF13847.6 ETS76005.1 - 4.3e-13 49.3 0.0 3.2e-08 33.5 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 ETS76005.1 - 1e-07 31.9 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS76005.1 - 3.4e-06 27.7 0.0 1.1e-05 26.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS76005.1 - 8.6e-06 26.4 0.0 5e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS76005.1 - 6e-05 23.6 0.0 0.0048 17.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 ETS76005.1 - 7.7e-05 22.7 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 ETS76005.1 - 0.0035 17.7 0.0 0.0061 16.9 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MTS PF05175.14 ETS76005.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FAM176 PF14851.6 ETS76005.1 - 0.37 10.5 3.5 0.89 9.2 3.5 1.6 1 0 0 1 1 1 0 FAM176 family DUF4746 PF15928.5 ETS76005.1 - 0.55 9.6 5.5 4.4 6.6 7.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) NOA36 PF06524.12 ETS76005.1 - 0.79 9.0 6.4 1.3 8.3 6.4 1.2 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 ETS76005.1 - 4.5 6.3 7.6 3.5 6.7 5.3 1.8 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Aminotran_4 PF01063.19 ETS76006.1 - 2.6 7.9 5.9 0.36 10.7 0.6 2.2 2 0 0 2 2 2 0 Amino-transferase class IV Pro-kuma_activ PF09286.11 ETS76009.1 - 7e-35 120.4 0.1 1.6e-34 119.2 0.1 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ETS76009.1 - 7.7e-08 31.9 0.1 1.4e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Subtilase family SBF_like PF13593.6 ETS76010.1 - 8.2e-90 301.3 13.6 9.6e-90 301.1 13.6 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 ETS76010.1 - 3.1e-12 46.6 8.5 3.1e-12 46.6 8.5 2.2 2 0 0 2 2 2 1 Sodium Bile acid symporter family GFA PF04828.14 ETS76011.1 - 0.008 16.5 0.1 0.02 15.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_1 PF00232.18 ETS76012.1 - 1.4e-151 504.9 0.0 1.7e-151 504.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 HET PF06985.11 ETS76013.1 - 2.5e-28 99.3 0.6 4.4e-28 98.5 0.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3989 PF13150.6 ETS76014.1 - 0.17 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) Vps16_N PF04841.13 ETS76015.1 - 2.7e-96 322.9 0.0 5.1e-96 321.9 0.0 1.4 2 0 0 2 2 2 1 Vps16, N-terminal region Vps16_C PF04840.12 ETS76015.1 - 1.1e-83 280.9 0.0 1.7e-83 280.4 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 ETS76015.1 - 0.0023 18.2 0.0 0.25 11.7 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Myotub-related PF06602.14 ETS76016.1 - 6e-147 489.2 0.0 7.7e-147 488.8 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Ribosomal_S3_C PF00189.20 ETS76017.1 - 4.1e-25 88.1 0.2 2.3e-24 85.7 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 ETS76017.1 - 6.2e-12 45.2 0.1 1.1e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 ETS76017.1 - 0.085 12.7 0.4 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 Coilin N-terminus UN_NPL4 PF11543.8 ETS76017.1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mg_trans_NIPA PF05653.14 ETS76018.1 - 1.6e-99 332.8 16.5 1.9e-99 332.5 16.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ETS76018.1 - 4.1e-06 27.0 7.0 4.1e-06 27.0 7.0 3.2 3 0 0 3 3 3 2 EamA-like transporter family DUF2420 PF10336.9 ETS76019.1 - 3.5e-09 36.6 0.0 6.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.21 ETS76020.1 - 3.7e-17 62.6 0.0 5.3e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ETS76020.1 - 1.8e-08 34.4 0.1 2.9e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 ETS76020.1 - 0.0083 16.5 0.3 0.015 15.7 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) ANAPC4 PF12896.7 ETS76021.1 - 5.6e-67 225.2 0.7 8.4e-67 224.6 0.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 ETS76021.1 - 2.8e-21 75.6 0.2 3e-19 69.1 0.1 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain AMP-binding PF00501.28 ETS76023.1 - 2.9e-74 250.2 0.0 3.7e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS76023.1 - 4.4e-20 72.4 0.1 1.1e-19 71.2 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DCP2 PF05026.13 ETS76024.1 - 1.6e-30 105.2 2.0 3.1e-30 104.3 2.0 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 ETS76024.1 - 9.4e-16 58.1 0.0 2.4e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.25 ETS76027.1 - 1.3e-61 208.3 0.0 2.1e-61 207.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS76027.1 - 2.3e-29 102.5 0.1 5.8e-29 101.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 ETS76027.1 - 0.02 14.2 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ETS76027.1 - 0.053 12.8 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF4887 PF16228.5 ETS76027.1 - 0.49 10.6 16.0 0.92 9.7 16.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) APH PF01636.23 ETS76027.1 - 0.54 10.1 6.3 2.2 8.2 5.6 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family LCD1 PF09798.9 ETS76027.1 - 1.7 7.1 5.4 2.3 6.6 5.4 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF5401 PF17380.2 ETS76027.1 - 6.3 4.7 17.8 9.2 4.2 17.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Methyltransf_28 PF02636.17 ETS76028.1 - 1.2e-79 267.7 0.0 1.5e-79 267.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase HET PF06985.11 ETS76029.1 - 1.5e-27 96.7 0.9 2.9e-27 95.8 0.9 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 ETS76031.1 - 1.4e-23 83.7 0.0 2.6e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS76031.1 - 3.4e-23 82.2 0.0 6.8e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HET PF06985.11 ETS76031.1 - 6.4e-21 75.2 0.0 1.8e-20 73.8 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.23 ETS76031.1 - 0.03 14.2 0.0 15 5.4 0.0 2.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family MFS_1 PF07690.16 ETS76033.1 - 1.6e-53 181.9 30.7 1.6e-53 181.9 30.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS76033.1 - 1.7e-13 50.3 15.7 3.3e-13 49.3 15.7 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 ETS76033.1 - 2.9e-07 29.3 0.9 5e-07 28.5 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 ETS76033.1 - 5.4e-07 29.2 1.6 5.4e-07 29.2 1.6 2.4 3 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB SHP PF03579.13 ETS76033.1 - 0.091 12.7 1.0 0.25 11.4 1.0 1.7 1 0 0 1 1 1 0 Small hydrophobic protein OATP PF03137.20 ETS76033.1 - 2.4 6.3 19.3 0.0099 14.2 7.1 2.8 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S9 PF00326.21 ETS76034.1 - 3.3e-07 30.0 0.0 5.9e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1100 PF06500.11 ETS76034.1 - 1.2e-06 27.6 0.0 2.4e-06 26.7 0.0 1.4 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) BAAT_C PF08840.11 ETS76034.1 - 1.2e-06 28.6 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 ETS76034.1 - 0.0016 19.1 1.1 0.0032 18.1 1.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 ETS76034.1 - 0.0019 17.8 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ETS76034.1 - 0.0026 17.4 0.2 0.006 16.3 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.8 ETS76034.1 - 0.015 14.8 0.0 0.037 13.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Peptidase_S15 PF02129.18 ETS76034.1 - 0.038 13.6 0.1 0.092 12.3 0.0 1.7 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 ETS76034.1 - 0.048 12.3 0.0 0.086 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 ETS76034.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Sugar_tr PF00083.24 ETS76035.1 - 2.7e-30 105.7 24.5 4.1e-17 62.2 3.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ETS76035.1 - 2.3e-14 53.1 40.5 6.2e-09 35.2 16.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily 4HBT_3 PF13622.6 ETS76036.1 - 4.3e-51 174.6 0.4 4.9e-51 174.4 0.4 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 ETS76036.1 - 0.078 13.3 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily Sugar_tr PF00083.24 ETS76037.1 - 2e-89 300.6 17.8 2.3e-89 300.3 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS76037.1 - 6.5e-23 81.2 38.2 8.3e-18 64.4 13.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ETS76037.1 - 7.2 4.8 15.5 2.1 6.6 0.5 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Chitin_synth_2 PF03142.15 ETS76038.1 - 2.3e-42 145.3 3.3 1.2e-32 113.3 1.2 2.1 1 1 0 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.26 ETS76038.1 - 3.2e-05 23.8 0.0 0.017 15.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 ETS76038.1 - 5.1e-05 23.3 11.1 5.1e-05 23.3 11.1 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DUF2207 PF09972.9 ETS76038.1 - 0.01 14.6 2.1 0.074 11.8 0.6 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4306 PF14154.6 ETS76038.1 - 0.96 9.7 9.7 0.056 13.6 3.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4306) UDPG_MGDP_dh PF00984.19 ETS76039.1 - 1.1e-19 70.4 0.0 5.2e-19 68.2 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 ETS76039.1 - 9.9e-18 64.4 0.0 6.6e-16 58.4 0.0 2.3 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 ETS76039.1 - 0.00088 19.5 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.15 ETS76039.1 - 0.0012 19.3 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain F420_oxidored PF03807.17 ETS76039.1 - 0.0023 18.5 0.0 0.096 13.3 0.0 2.6 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Methyltransf_25 PF13649.6 ETS76039.1 - 0.007 17.0 0.0 0.021 15.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TrkA_N PF02254.18 ETS76039.1 - 0.012 15.8 0.0 0.39 11.0 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Methyltransf_11 PF08241.12 ETS76039.1 - 0.062 14.0 0.0 0.22 12.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Glyco_hydro_18 PF00704.28 ETS76040.1 - 1.8e-61 208.6 0.0 2e-61 208.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3716 PF12511.8 ETS76041.1 - 1.2e-16 60.5 8.3 1.9e-16 59.8 8.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Chorion_2 PF03964.15 ETS76041.1 - 0.098 13.5 3.7 0.3 11.9 3.7 1.9 1 0 0 1 1 1 0 Chorion family 2 NicO PF03824.16 ETS76041.1 - 0.1 11.9 9.5 0.18 11.1 9.5 1.4 1 0 0 1 1 1 0 High-affinity nickel-transport protein Trypan_PARP PF05887.11 ETS76041.1 - 0.14 12.2 10.3 0.35 10.9 10.3 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Presenilin PF01080.17 ETS76041.1 - 7.3 5.2 6.1 11 4.7 6.1 1.3 1 0 0 1 1 1 0 Presenilin DUF1771 PF08590.10 ETS76042.1 - 2e-25 89.0 9.3 6.4e-25 87.3 9.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 ETS76042.1 - 3.1e-11 43.4 0.4 3.1e-11 43.4 0.4 2.1 2 0 0 2 2 2 1 Smr domain G-alpha PF00503.20 ETS76043.1 - 6.9e-125 416.9 3.1 8e-125 416.7 3.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ETS76043.1 - 3.7e-15 55.8 2.0 2.8e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 ETS76043.1 - 7.3e-05 22.5 0.0 0.00032 20.5 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 ETS76043.1 - 0.0032 16.9 3.8 0.089 12.1 0.1 2.7 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 ETS76043.1 - 0.014 15.2 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 ETS76043.1 - 0.022 14.9 0.2 2.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 ETS76043.1 - 0.058 12.5 0.1 0.11 11.6 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain GTP_EFTU PF00009.27 ETS76043.1 - 0.11 12.0 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 ETS76043.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 ETS76043.1 - 0.13 12.3 0.1 8.7 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase GST_N PF02798.20 ETS76044.1 - 8.3e-11 42.1 0.2 3.5e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ETS76044.1 - 1.8e-08 34.5 0.0 3.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ETS76044.1 - 9.7e-08 31.9 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ETS76044.1 - 3.4e-07 30.6 0.0 1.2e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ETS76044.1 - 5.6e-07 29.8 0.1 3e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ETS76044.1 - 2.9e-05 24.2 0.0 5.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Prp18 PF02840.15 ETS76045.1 - 8.6e-55 184.7 0.0 8.6e-55 184.7 0.0 2.0 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 ETS76045.1 - 9.6e-12 44.2 0.8 9.6e-12 44.2 0.8 2.8 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like DUF966 PF06136.13 ETS76045.1 - 0.056 13.2 7.5 0.07 12.8 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CDC45 PF02724.14 ETS76045.1 - 2.1 6.6 11.9 2.4 6.4 11.9 1.2 1 0 0 1 1 1 0 CDC45-like protein MAJIN PF15077.6 ETS76045.1 - 3.1 7.5 7.4 5.5 6.7 7.4 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein SAP18 PF06487.12 ETS76046.1 - 1.1e-38 132.6 0.0 1.4e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) RPN7 PF10602.9 ETS76047.1 - 1.4e-35 122.6 0.2 2.7e-35 121.6 0.0 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 ETS76047.1 - 4.3e-15 56.1 0.5 1.6e-14 54.3 0.1 2.1 2 0 0 2 2 2 1 PCI domain Fungal_trans PF04082.18 ETS76048.1 - 2.3e-27 95.7 0.0 3.7e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS76048.1 - 4.5e-11 42.7 13.8 7.5e-11 42.0 13.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 4F5 PF04419.14 ETS76048.1 - 0.2 12.5 0.7 0.52 11.2 0.7 1.7 1 0 0 1 1 1 0 4F5 protein family Gal4_dimer PF03902.13 ETS76048.1 - 0.91 9.7 2.3 0.72 10.1 0.1 2.0 2 0 0 2 2 2 0 Gal4-like dimerisation domain TEBP_beta PF07404.11 ETS76048.1 - 1.9 7.7 3.6 3.3 7.0 3.6 1.3 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Peptidase_M24 PF00557.24 ETS76049.1 - 2.9e-56 190.5 0.0 4e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ETS76049.1 - 4.9e-19 68.3 0.0 7.9e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Abhydrolase_6 PF12697.7 ETS76050.1 - 0.003 18.2 4.4 0.042 14.5 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS76050.1 - 0.036 13.3 0.0 0.067 12.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 ETS76050.1 - 0.041 13.4 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Palm_thioest PF02089.15 ETS76050.1 - 0.087 12.6 0.0 0.49 10.2 0.0 1.9 2 0 0 2 2 2 0 Palmitoyl protein thioesterase LCAT PF02450.15 ETS76050.1 - 0.24 10.5 0.0 0.45 9.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase WAC_Acf1_DNA_bd PF10537.9 ETS76051.1 - 6.4e-41 139.0 2.2 1.1e-40 138.2 0.0 2.5 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 ETS76051.1 - 3.6e-18 65.9 0.1 3.6e-18 65.9 0.1 3.9 4 1 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 ETS76051.1 - 8.9e-15 54.7 0.1 2e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 ETS76051.1 - 1.3e-06 27.8 0.1 0.0001 21.7 0.0 2.6 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 Nop53 PF07767.11 ETS76051.1 - 1.4 8.2 51.2 0.054 12.9 4.5 3.3 3 0 0 3 3 3 0 Nop53 (60S ribosomal biogenesis) CRA PF06589.11 ETS76051.1 - 2.2 8.4 6.4 8.5 6.5 6.4 2.0 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Alg6_Alg8 PF03155.15 ETS76052.1 - 3.8e-176 586.8 27.8 4.4e-176 586.6 27.8 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family VIT1 PF01988.19 ETS76052.1 - 0.024 14.5 4.8 0.13 12.2 0.4 2.6 2 0 0 2 2 2 0 VIT family Lectin_leg-like PF03388.13 ETS76053.1 - 3.5e-23 82.2 0.0 5.8e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family DUF4435 PF14491.6 ETS76053.1 - 0.0036 17.2 1.4 0.01 15.7 1.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4435) DUF2408 PF10303.9 ETS76053.1 - 0.0093 16.5 1.9 0.017 15.7 1.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) CENP-F_leu_zip PF10473.9 ETS76053.1 - 0.025 14.6 3.7 0.049 13.6 2.9 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4011 PF13195.6 ETS76053.1 - 0.029 14.3 0.6 0.047 13.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Laminin_II PF06009.12 ETS76053.1 - 0.05 13.6 4.4 0.088 12.8 4.4 1.4 1 0 0 1 1 1 0 Laminin Domain II Baculo_PEP_C PF04513.12 ETS76053.1 - 0.11 12.5 2.0 0.2 11.7 2.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SKA2 PF16740.5 ETS76053.1 - 0.12 12.2 2.2 0.28 11.0 2.2 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 SURF6 PF04935.12 ETS76053.1 - 0.22 11.3 4.4 0.43 10.3 4.4 1.4 1 0 0 1 1 1 0 Surfeit locus protein 6 Fib_alpha PF08702.10 ETS76053.1 - 0.49 10.6 5.3 1.3 9.2 5.2 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TPD52 PF04201.15 ETS76053.1 - 0.55 9.8 4.5 6.4 6.4 3.8 2.0 1 1 0 1 1 1 0 Tumour protein D52 family Siah-Interact_N PF09032.11 ETS76053.1 - 2.2 8.6 6.1 1.2 9.5 2.0 2.2 2 0 0 2 2 2 0 Siah interacting protein, N terminal STAT1_TAZ2bind PF12162.8 ETS76054.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain MIF PF01187.18 ETS76055.1 - 1.2e-06 28.7 0.0 1.9e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Gtr1_RagA PF04670.12 ETS76056.1 - 8.9e-69 231.4 0.2 1.1e-68 231.1 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 ETS76056.1 - 0.00078 18.9 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ETS76056.1 - 0.015 15.5 0.0 0.034 14.4 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 ETS76056.1 - 0.035 14.5 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 ETS76056.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Pkinase PF00069.25 ETS76057.1 - 1.1e-76 257.7 0.0 1.3e-76 257.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS76057.1 - 6.4e-38 130.5 0.0 9.1e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ETS76057.1 - 0.011 14.7 0.1 0.21 10.5 0.0 2.5 2 1 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 ETS76057.1 - 0.058 12.7 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ETS76057.1 - 0.11 11.8 0.0 0.38 10.0 0.0 1.9 1 1 0 2 2 2 0 Kinase-like Septin PF00735.18 ETS76058.1 - 4.4e-18 65.5 0.0 1.6e-15 57.1 0.0 2.1 2 0 0 2 2 2 2 Septin MMR_HSR1 PF01926.23 ETS76058.1 - 0.0049 16.9 0.0 0.031 14.4 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Phage_holin_2_1 PF04971.12 ETS76058.1 - 0.088 12.8 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacteriophage P21 holin S PAP_central PF04928.17 ETS76059.1 - 2e-104 348.0 0.0 2.6e-104 347.6 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 ETS76059.1 - 4.6e-61 205.4 0.0 1e-60 204.2 0.0 1.6 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 ETS76059.1 - 1.7e-07 31.4 0.0 3.9e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 ETS76059.1 - 0.18 11.5 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain SCA7 PF08313.12 ETS76061.1 - 1.3e-32 111.4 0.1 4.5e-32 109.8 0.1 1.9 1 0 0 1 1 1 1 SCA7, zinc-binding domain CDC45 PF02724.14 ETS76061.1 - 0.33 9.2 12.7 0.56 8.4 12.7 1.4 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 ETS76061.1 - 2.1 6.8 7.5 3.6 6.0 7.5 1.4 1 0 0 1 1 1 0 Macoilin family Mito_carr PF00153.27 ETS76062.1 - 1.6e-39 133.7 0.4 1.5e-12 47.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-NOSIP PF15906.5 ETS76063.1 - 2.5e-09 37.1 0.0 4.5e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 ETS76063.1 - 1.5e-08 34.5 8.5 5.8e-05 23.0 2.4 2.7 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 ETS76063.1 - 2.9e-06 27.1 16.2 0.00027 20.7 1.9 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ETS76063.1 - 4.4e-06 26.4 15.9 0.00024 20.9 3.0 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ETS76063.1 - 2e-05 24.8 16.7 0.00058 20.1 4.9 3.1 3 1 1 4 4 4 2 Ring finger domain zf-C3HC4_3 PF13920.6 ETS76063.1 - 0.00058 19.7 18.4 0.0062 16.4 8.1 3.2 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ETS76063.1 - 0.00071 19.7 15.1 0.16 12.1 1.3 3.2 2 1 1 3 3 3 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 ETS76063.1 - 0.00072 19.5 5.5 0.00072 19.5 5.5 3.1 2 2 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_5 PF17121.5 ETS76063.1 - 0.0024 17.7 1.9 0.0063 16.4 1.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 ETS76063.1 - 0.021 14.6 5.1 2.6 7.9 0.3 3.5 3 0 0 3 3 3 0 Rad50 zinc hook motif Hexokinase_1 PF00349.21 ETS76063.1 - 0.022 14.7 0.1 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Hexokinase FYVE PF01363.21 ETS76063.1 - 0.21 11.8 16.0 0.12 12.5 6.3 3.4 2 2 0 2 2 2 0 FYVE zinc finger Prok-RING_4 PF14447.6 ETS76063.1 - 1.4 8.8 19.1 0.19 11.6 6.3 3.7 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 Acyltransferase PF01553.21 ETS76064.1 - 1.4e-13 50.6 0.0 2.9e-13 49.6 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase Nnf1 PF03980.14 ETS76065.1 - 7e-35 119.7 2.0 1.1e-34 119.1 2.0 1.3 1 0 0 1 1 1 1 Nnf1 TolA_bind_tri PF16331.5 ETS76065.1 - 0.0031 17.5 1.5 0.0031 17.5 1.5 1.6 2 0 0 2 2 2 1 TolA binding protein trimerisation Dynamin_M PF01031.20 ETS76065.1 - 0.052 12.8 0.5 0.53 9.5 0.3 2.0 2 0 0 2 2 2 0 Dynamin central region SHE3 PF17078.5 ETS76065.1 - 0.14 11.9 3.9 0.056 13.1 1.3 1.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 ADIP PF11559.8 ETS76065.1 - 0.16 12.1 3.6 0.1 12.7 1.2 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Uso1_p115_C PF04871.13 ETS76065.1 - 0.51 10.7 4.8 1.1 9.6 4.8 1.6 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region PH_9 PF15410.6 ETS76066.1 - 0.00062 20.1 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain NTF2 PF02136.20 ETS76067.1 - 6.3e-23 81.6 0.6 1e-22 81.0 0.6 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 ETS76067.1 - 1.9e-09 37.2 0.0 3.5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ETS76067.1 - 4.2e-05 23.5 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif AA_permease_C PF13906.6 ETS76068.1 - 0.0069 16.4 0.8 0.018 15.1 0.8 1.7 1 0 0 1 1 1 1 C-terminus of AA_permease Ion_trans PF00520.31 ETS76068.1 - 0.021 14.1 0.1 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 Ion transport protein Cytochrom_B561 PF03188.16 ETS76068.1 - 0.031 14.4 12.5 0.035 14.3 9.1 2.3 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 DUF2427 PF10348.9 ETS76068.1 - 0.24 11.2 3.1 0.5 10.2 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DUF4079 PF13301.6 ETS76068.1 - 2.8 8.1 15.6 4.9 7.3 4.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) Cation_ATPase_C PF00689.21 ETS76068.1 - 6.2 6.5 7.9 11 5.7 7.9 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF1640 PF07798.11 ETS76069.1 - 6.6e-44 150.0 4.6 6.6e-44 150.0 4.6 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1640) DUF4407 PF14362.6 ETS76069.1 - 2.7 7.3 11.1 0.35 10.2 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) cwf21 PF08312.12 ETS76070.1 - 5.8e-18 64.8 9.7 5.8e-18 64.8 9.7 2.1 2 1 0 2 2 2 1 cwf21 domain D123 PF07065.14 ETS76071.1 - 1.2e-111 372.8 0.0 1.4e-111 372.6 0.0 1.0 1 0 0 1 1 1 1 D123 Gly-rich_Ago1 PF12764.7 ETS76071.1 - 0.026 15.3 0.7 1.8 9.4 0.1 2.3 2 0 0 2 2 2 0 Glycine-rich region of argonaut Cwf_Cwc_15 PF04889.12 ETS76071.1 - 2 8.1 21.1 0.088 12.5 3.7 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 ETS76071.1 - 8.3 6.2 8.3 14 5.5 1.1 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Amidohydro_3 PF07969.11 ETS76072.1 - 3.5e-16 59.7 1.4 9.4e-10 38.5 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 ETS76072.1 - 5.2e-12 45.7 0.4 1.3e-09 37.9 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family Response_reg PF00072.24 ETS76073.1 - 5.1e-18 65.3 0.0 1e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 ETS76073.1 - 2.2e-12 47.4 0.0 4.4e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ETS76073.1 - 1.1e-10 41.4 0.1 4.5e-10 39.4 0.1 2.1 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 ETS76073.1 - 0.18 11.6 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PikAIV_N PF18605.1 ETS76073.1 - 2.8 7.6 6.9 0.55 9.9 2.7 2.1 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF3425 PF11905.8 ETS76075.1 - 2.1e-20 72.9 0.0 5.8e-20 71.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 ETS76075.1 - 1 9.5 6.4 1.8 8.7 6.4 1.2 1 0 0 1 1 1 0 bZIP transcription factor adh_short PF00106.25 ETS76076.1 - 3.1e-22 79.0 0.0 1.3e-16 60.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS76076.1 - 5e-12 45.9 0.0 6.3e-10 39.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS76076.1 - 0.0047 16.8 0.0 0.0075 16.2 0.0 1.3 1 0 0 1 1 1 1 KR domain TIR-like PF10137.9 ETS76076.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Zn_clus PF00172.18 ETS76077.1 - 3.2e-07 30.4 4.5 5.9e-07 29.5 4.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS76077.1 - 0.025 13.6 0.4 0.094 11.7 0.2 2.0 2 1 0 2 2 2 0 Fungal specific transcription factor domain UPF0506 PF11703.8 ETS76077.1 - 2.1 8.8 7.5 1.4 9.4 4.6 2.2 2 0 0 2 2 2 0 UPF0506 Fasciclin PF02469.22 ETS76078.1 - 1.4e-32 112.6 0.2 2.1e-18 66.8 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain Glyco_hydro_47 PF01532.20 ETS76079.1 - 1.2e-131 439.8 0.0 1.5e-131 439.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PATR PF12951.7 ETS76079.1 - 0.12 12.5 9.1 0.68 10.1 4.0 2.8 2 0 0 2 2 2 0 Passenger-associated-transport-repeat SKG6 PF08693.10 ETS76079.1 - 0.19 11.2 2.0 0.37 10.3 2.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VSP PF03302.13 ETS76080.1 - 0.00038 19.4 0.4 0.00038 19.4 0.4 1.4 2 0 0 2 2 2 1 Giardia variant-specific surface protein DUF4448 PF14610.6 ETS76080.1 - 0.069 12.9 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Phage_holin_3_6 PF07332.11 ETS76080.1 - 0.073 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4690 PF15756.5 ETS76080.1 - 0.1 13.2 5.0 0.21 12.2 4.7 1.7 1 1 0 1 1 1 0 Small Novel Rich in Cartilage DUF5585 PF17823.1 ETS76080.1 - 0.19 10.7 15.9 0.24 10.3 15.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) BES1_N PF05687.13 ETS76080.1 - 2.2 8.6 10.6 3.5 8.0 10.6 1.2 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Fringe PF02434.16 ETS76082.1 - 2.3e-07 30.5 0.0 4.9e-06 26.2 0.0 2.4 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 ETS76082.1 - 0.045 13.7 2.2 0.095 12.6 2.2 1.6 1 0 0 1 1 1 0 PAN domain Beta-lactamase PF00144.24 ETS76083.1 - 3.8e-48 164.4 0.0 7.2e-48 163.5 0.0 1.4 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.8 ETS76083.1 - 1.2e-14 54.6 0.1 2.1e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Hydrolase_4 PF12146.8 ETS76084.1 - 1.2e-13 51.0 0.0 2.9e-13 49.7 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS76084.1 - 5.4e-13 50.1 0.5 7.3e-13 49.6 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS76084.1 - 1.4e-12 47.8 0.1 5.9e-12 45.8 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 ETS76084.1 - 0.061 13.0 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.18 ETS76084.1 - 0.096 12.3 0.1 0.38 10.3 0.1 1.9 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Cu-oxidase_2 PF07731.14 ETS76085.1 - 1.6e-25 89.5 5.3 2.4e-23 82.4 3.2 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ETS76085.1 - 1.5e-15 57.3 0.2 4.9e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 ETS76085.1 - 5.9e-06 26.5 0.0 4.5e-05 23.6 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase CMAS PF02353.20 ETS76087.1 - 4.6e-62 209.8 0.0 5.9e-62 209.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 ETS76087.1 - 8.7e-10 38.7 0.0 1.4e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS76087.1 - 3.1e-09 37.3 0.0 7e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS76087.1 - 9e-09 35.9 0.0 2.4e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS76087.1 - 0.00036 20.1 0.0 0.00062 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 ETS76087.1 - 0.0015 19.2 0.0 0.0032 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 ETS76087.1 - 0.0037 16.8 0.0 0.0057 16.2 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 ETS76087.1 - 0.006 16.4 0.0 0.0099 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ETS76087.1 - 0.039 13.7 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 ETS76087.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.7 ETS76088.1 - 1.6e-31 108.7 8.7 9.3e-12 45.4 0.7 4.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS76088.1 - 2e-20 72.9 3.9 8.6e-06 26.2 0.3 4.9 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS76088.1 - 1e-18 67.1 4.3 2.1e-09 37.5 0.5 6.0 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS76088.1 - 7.1e-15 53.6 3.2 0.00033 20.9 0.1 7.6 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 ETS76088.1 - 2.5e-14 53.0 6.9 7e-05 23.1 0.7 6.8 7 0 0 7 7 7 2 Ankyrin repeat Ank_2 PF12796.7 ETS76089.1 - 3.6e-11 43.5 0.0 2.9e-06 27.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS76089.1 - 1.1e-10 41.9 0.0 0.0001 22.8 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS76089.1 - 2.1e-08 34.3 0.0 0.0022 18.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS76089.1 - 1.7e-05 24.8 0.0 1.7 9.4 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 ETS76089.1 - 0.0091 16.4 0.0 0.85 10.2 0.0 2.9 3 1 0 3 3 3 1 Ankyrin repeat GFA PF04828.14 ETS76092.1 - 0.0003 21.1 1.1 0.00047 20.4 0.3 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 ETS76092.1 - 0.0059 16.3 2.4 0.0059 16.3 2.4 2.2 3 0 0 3 3 3 1 NADH pyrophosphatase zinc ribbon domain SKG6 PF08693.10 ETS76094.1 - 0.011 15.1 1.4 0.019 14.4 0.0 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain LapA_dom PF06305.11 ETS76094.1 - 0.03 14.1 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Adeno_100 PF02438.16 ETS76094.1 - 0.13 10.4 0.0 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Late 100kD protein HET PF06985.11 ETS76095.1 - 1.4e-30 106.5 0.0 2.1e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LAB_N PF07578.11 ETS76097.1 - 0.063 13.4 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain Ank_2 PF12796.7 ETS76098.1 - 9.7e-30 103.0 0.0 1.7e-10 41.4 0.0 5.7 4 1 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS76098.1 - 1e-22 80.2 2.1 1.4e-06 28.7 0.0 8.1 5 3 4 9 9 9 5 Ankyrin repeats (many copies) Pkinase PF00069.25 ETS76098.1 - 2.1e-22 79.7 0.0 3.7e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS76098.1 - 8.2e-18 64.6 0.0 2.1e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 ETS76098.1 - 9.2e-16 56.4 2.5 0.00078 19.7 0.0 9.3 11 0 0 11 11 11 2 Ankyrin repeat Ank_5 PF13857.6 ETS76098.1 - 9.4e-15 54.5 1.1 0.00011 22.4 0.0 6.9 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 ETS76098.1 - 2e-11 43.8 4.3 0.00012 22.3 0.0 7.1 9 0 0 9 9 9 2 Ankyrin repeat Sel1 PF08238.12 ETS76098.1 - 0.00063 20.3 0.0 0.011 16.5 0.0 2.7 2 0 0 2 2 2 1 Sel1 repeat HeLo PF14479.6 ETS76099.1 - 7.7e-13 48.7 0.0 1.3e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation SnoaL_4 PF13577.6 ETS76100.1 - 5.2e-11 42.8 0.0 6e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain OLF PF02191.16 ETS76100.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Olfactomedin-like domain PrpF PF04303.13 ETS76101.1 - 1.3e-64 218.5 5.2 1.4e-64 218.4 5.2 1.0 1 0 0 1 1 1 1 PrpF protein PS-DH PF14765.6 ETS76101.1 - 0.0045 16.3 0.8 0.008 15.4 0.2 1.6 2 0 0 2 2 2 1 Polyketide synthase dehydratase Mito_carr PF00153.27 ETS76102.1 - 1.5e-25 89.0 6.1 1.5e-11 44.0 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3482 PF11981.8 ETS76102.1 - 0.15 11.4 0.8 0.3 10.4 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Aconitase PF00330.20 ETS76103.1 - 3.6e-145 484.5 0.0 4.5e-145 484.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ETS76103.1 - 1.7e-38 131.9 0.0 3.1e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Sporozoite_P67 PF05642.11 ETS76105.1 - 0.012 13.7 6.7 0.018 13.2 6.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Menin PF05053.13 ETS76105.1 - 0.54 8.6 11.2 0.95 7.8 11.2 1.3 1 0 0 1 1 1 0 Menin Roughex PF06020.11 ETS76105.1 - 1 8.4 7.9 2 7.4 7.9 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Zip PF02535.22 ETS76106.1 - 3.5e-28 98.8 10.3 6.9e-28 97.8 10.3 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter TauE PF01925.19 ETS76106.1 - 7 6.2 17.6 0.24 11.0 3.3 2.5 2 1 0 2 2 2 0 Sulfite exporter TauE/SafE Endonuclease_NS PF01223.23 ETS76107.1 - 2.2e-66 223.9 0.0 2.6e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease WD40 PF00400.32 ETS76108.1 - 5.8e-29 99.7 21.7 0.00028 21.6 0.5 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS76108.1 - 5.5e-12 45.8 0.0 0.031 14.6 0.0 5.0 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ETS76108.1 - 0.016 15.1 0.1 2 8.2 0.0 2.7 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A MBOAT PF03062.19 ETS76109.1 - 1.3e-23 83.9 16.9 2.1e-23 83.3 16.9 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 ETS76109.1 - 1.6e-05 25.0 1.6 1.6e-05 25.0 1.6 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MFS_1 PF07690.16 ETS76110.1 - 4.5e-16 58.7 40.2 6.8e-08 31.8 8.7 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 ETS76110.1 - 0.012 15.7 0.6 0.012 15.7 0.6 5.2 4 2 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III Corona_nucleoca PF00937.18 ETS76110.1 - 2.8 6.9 6.6 4.2 6.3 6.6 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein bZIP_1 PF00170.21 ETS76111.1 - 7.4e-06 26.0 6.7 1.4e-05 25.1 6.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ETS76111.1 - 0.79 9.9 9.1 0.93 9.6 7.9 1.8 1 1 0 1 1 1 0 Basic region leucine zipper LPD39 PF18858.1 ETS76111.1 - 1.7 8.7 10.6 1.1 9.3 5.2 2.1 2 0 0 2 2 2 0 Large polyvalent protein associated domain 39 GvpL_GvpF PF06386.11 ETS76111.1 - 3.1 7.6 6.7 0.64 9.9 2.5 1.8 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Stm1_N PF09598.10 ETS76112.1 - 2e-14 54.2 1.1 2e-14 54.2 1.1 4.0 3 1 0 3 3 3 1 Stm1 HABP4_PAI-RBP1 PF04774.15 ETS76112.1 - 0.012 16.5 8.9 0.012 16.5 8.9 2.5 1 1 1 2 2 2 0 Hyaluronan / mRNA binding family NOA36 PF06524.12 ETS76113.1 - 0.17 11.1 3.7 0.22 10.8 3.7 1.1 1 0 0 1 1 1 0 NOA36 protein zf-C2H2 PF00096.26 ETS76114.1 - 1.6e-27 94.4 59.4 9e-06 25.9 0.2 11.0 10 1 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS76114.1 - 2.6e-21 74.5 59.9 0.019 15.8 0.5 11.4 11 0 0 11 11 11 9 C2H2-type zinc finger FOXP-CC PF16159.5 ETS76114.1 - 1.3e-10 41.7 38.7 0.001 19.6 0.1 9.3 4 2 6 10 10 10 5 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 ETS76114.1 - 1.3e-09 38.1 50.8 1.6e-05 25.1 1.2 9.7 10 0 0 10 10 10 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ETS76114.1 - 1.6e-09 37.8 25.6 0.2 12.0 0.4 10.2 11 0 0 11 11 11 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ETS76114.1 - 7.1e-06 26.2 20.4 2.6 8.5 0.1 8.4 9 0 0 9 9 9 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ETS76114.1 - 1.5e-05 25.2 25.8 1.1 9.7 0.1 6.1 3 1 3 7 7 7 3 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 ETS76114.1 - 3.8e-05 23.9 17.7 0.091 12.9 1.3 6.3 4 2 2 6 6 6 2 Aberrant zinc-finger zf-CRD PF17979.1 ETS76114.1 - 0.0026 17.9 1.9 0.0026 17.9 1.9 2.9 2 1 0 2 2 2 1 Cysteine rich domain with multizinc binding regions CHORD PF04968.12 ETS76114.1 - 0.0043 17.7 28.2 0.087 13.6 0.3 7.0 5 2 3 8 8 8 1 CHORD zf-BED PF02892.15 ETS76114.1 - 0.25 11.4 0.1 0.25 11.4 0.1 6.7 8 0 0 8 8 8 0 BED zinc finger XPA_N PF01286.18 ETS76114.1 - 8.3 6.6 7.9 56 3.9 0.3 4.3 4 0 0 4 4 4 0 XPA protein N-terminal RNA_pol_Rpb6 PF01192.22 ETS76115.1 - 1.1e-17 63.7 0.1 2.3e-17 62.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb6 eIF3_subunit PF08597.10 ETS76115.1 - 0.011 15.7 5.7 0.014 15.3 5.7 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Pro_Al_protease PF02983.14 ETS76115.1 - 0.16 12.1 0.5 0.21 11.7 0.5 1.2 1 0 0 1 1 1 0 Alpha-lytic protease prodomain Esterase PF00756.20 ETS76116.1 - 4.5e-54 183.7 0.0 5.2e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 ETS76116.1 - 8.4e-07 28.7 0.1 3.5e-06 26.7 0.1 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 ETS76116.1 - 0.0003 20.1 0.0 0.0007 18.9 0.0 1.6 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ETS76116.1 - 0.00077 19.0 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 ETS76116.1 - 0.011 14.7 0.0 0.052 12.5 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 ETS76116.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 ETS76116.1 - 0.034 14.7 1.5 0.064 13.9 1.5 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS76116.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 ETS76116.1 - 0.088 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 ETS76116.1 - 0.089 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PGAP1 PF07819.13 ETS76116.1 - 0.099 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase PF07224.11 ETS76116.1 - 0.17 10.9 0.1 0.69 8.9 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase Afi1 PF07792.12 ETS76117.1 - 1.3e-47 161.6 3.1 2.3e-47 160.8 3.1 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 ETS76117.1 - 2e-35 121.2 0.0 3.6e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 ETS76117.1 - 1.7e-08 33.6 0.0 0.0073 15.0 0.0 3.8 3 1 0 4 4 4 2 Transport protein Avl9 TFIIA PF03153.13 ETS76117.1 - 0.065 13.2 11.5 0.13 12.3 11.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2347 PF09804.9 ETS76117.1 - 0.11 12.0 0.0 0.9 9.1 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Cwf_Cwc_15 PF04889.12 ETS76117.1 - 0.2 11.4 16.9 0.36 10.5 16.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1168 PF06658.12 ETS76117.1 - 0.26 11.1 11.4 0.53 10.1 11.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Nop14 PF04147.12 ETS76117.1 - 1.2 7.2 13.2 1.8 6.7 13.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 ETS76117.1 - 3.5 7.0 8.0 5.8 6.3 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) QWRF PF04484.12 ETS76117.1 - 3.6 7.2 7.6 6.3 6.4 7.6 1.3 1 0 0 1 1 1 0 QWRF family Astro_capsid_p PF12226.8 ETS76117.1 - 9 5.3 7.8 14 4.7 7.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein EF-hand_6 PF13405.6 ETS76118.1 - 1.1e-11 43.7 0.7 1.8e-05 24.3 0.2 2.7 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 ETS76118.1 - 9.6e-10 37.3 1.5 0.00091 18.6 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 ETS76118.1 - 3.9e-08 33.6 1.8 1.3e-05 25.6 0.7 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 ETS76118.1 - 7.9e-06 26.1 0.0 0.037 14.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 ETS76118.1 - 9.4e-06 24.9 4.9 0.017 14.6 0.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 ETS76118.1 - 1.3e-05 24.9 0.0 0.069 13.0 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair UPF0154 PF03672.13 ETS76118.1 - 0.02 14.9 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) TPR_1 PF00515.28 ETS76119.1 - 3e-42 140.8 18.8 4e-09 35.9 0.1 9.1 9 1 1 10 10 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 ETS76119.1 - 5.8e-36 119.7 20.2 3.4e-06 26.8 0.1 8.7 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 ETS76119.1 - 2.7e-31 107.0 19.6 1.1e-08 34.6 0.3 7.7 5 2 3 8 8 8 5 TPR repeat DnaJ PF00226.31 ETS76119.1 - 4.6e-28 97.1 3.7 6.8e-28 96.6 2.3 2.1 2 0 0 2 2 1 1 DnaJ domain TPR_19 PF14559.6 ETS76119.1 - 6.2e-24 84.3 14.1 9.3e-09 35.7 0.0 6.3 3 3 2 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 ETS76119.1 - 1.5e-23 83.2 11.4 5.9e-07 30.0 0.1 6.8 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 ETS76119.1 - 8.2e-23 78.7 6.8 0.00022 21.2 0.2 7.3 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 ETS76119.1 - 1.5e-18 65.8 10.5 0.0062 16.8 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 ETS76119.1 - 1e-17 64.1 9.4 0.00014 22.1 0.2 7.0 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 ETS76119.1 - 1.5e-17 62.7 15.6 2.2e-05 24.9 0.2 7.6 4 2 4 8 8 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS76119.1 - 3e-16 59.4 7.1 8.4e-09 35.5 0.1 3.9 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 ETS76119.1 - 4.1e-14 52.5 10.1 0.0005 20.2 0.2 5.2 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 ETS76119.1 - 1.5e-13 49.7 3.0 0.097 12.7 0.0 6.9 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 ETS76119.1 - 1.1e-09 38.2 14.0 0.016 15.8 0.1 7.4 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 ETS76119.1 - 3e-08 33.2 9.4 0.0022 17.2 0.1 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.17 ETS76119.1 - 2e-06 28.3 7.0 0.0064 16.9 0.0 4.3 2 1 1 3 3 3 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 ETS76119.1 - 2e-06 27.5 16.6 0.19 11.7 1.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 ETS76119.1 - 1.1e-05 25.6 3.6 0.34 11.7 0.0 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 ETS76119.1 - 3.5e-05 24.3 1.2 0.084 13.3 0.0 3.6 2 1 1 3 3 3 1 Alkyl sulfatase dimerisation NARP1 PF12569.8 ETS76119.1 - 6.3e-05 22.1 4.5 0.021 13.8 1.2 2.9 2 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 ETS76119.1 - 0.00018 21.8 7.5 0.74 10.2 0.1 4.8 3 2 1 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ETS76119.1 - 0.00072 19.6 3.8 6.4 6.9 0.1 4.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 ETS76119.1 - 0.0014 17.7 0.0 0.0026 16.8 0.0 1.4 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_MalT PF17874.1 ETS76119.1 - 0.0043 16.5 1.5 0.27 10.6 0.0 3.6 2 2 2 4 4 4 1 MalT-like TPR region Coatomer_E PF04733.14 ETS76119.1 - 0.0052 16.2 1.2 0.092 12.1 0.0 2.8 3 1 0 3 3 3 1 Coatomer epsilon subunit NatB_MDM20 PF09797.9 ETS76119.1 - 0.0085 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit MIT PF04212.18 ETS76119.1 - 0.023 14.7 9.3 4.1 7.6 0.1 4.9 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain RPT PF13446.6 ETS76119.1 - 0.087 12.8 0.1 0.73 9.8 0.0 2.6 3 0 0 3 3 2 0 A repeated domain in UCH-protein DUF3856 PF12968.7 ETS76119.1 - 0.11 12.6 5.6 58 3.7 0.0 5.6 4 2 2 6 6 6 0 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.9 ETS76119.1 - 0.11 12.0 0.4 13 5.3 0.0 3.3 4 0 0 4 4 2 0 SHNi-TPR TPR_21 PF09976.9 ETS76119.1 - 0.14 11.9 9.1 1.2 8.9 0.2 3.8 3 2 2 5 5 5 0 Tetratricopeptide repeat-like domain DUF627 PF04781.12 ETS76119.1 - 0.19 11.7 3.3 0.85 9.7 0.2 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF627) SRP_TPR_like PF17004.5 ETS76119.1 - 0.6 10.1 3.0 3.8 7.5 0.9 3.2 2 1 2 4 4 4 0 Putative TPR-like repeat Snurportin1 PF11538.8 ETS76119.1 - 1 9.6 5.5 20 5.4 0.6 3.3 3 0 0 3 3 2 0 Snurportin1 DUF357 PF04010.13 ETS76119.1 - 1.6 8.9 3.7 9.3 6.4 0.1 3.2 2 1 1 3 3 2 0 Protein of unknown function (DUF357) GSH_synth_ATP PF03917.17 ETS76120.1 - 3.5e-139 463.7 0.0 4e-139 463.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 ETS76120.1 - 2.2e-31 108.3 0.0 4.6e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase HET PF06985.11 ETS76121.1 - 1.6e-30 106.4 0.0 3.1e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SNF2_N PF00176.23 ETS76122.1 - 4.3e-42 144.1 0.3 7.9e-42 143.2 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS76122.1 - 7.6e-20 71.3 0.0 3.2e-19 69.3 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS76122.1 - 1.6e-07 31.5 0.0 6.2e-07 29.6 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ETS76122.1 - 0.0073 15.5 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 ETS76122.1 - 0.0077 15.9 3.0 1.2 8.7 0.0 3.4 4 0 0 4 4 4 2 SWI2/SNF2 ATPase Alk_phosphatase PF00245.20 ETS76124.1 - 3.7e-100 335.8 0.0 5.4e-100 335.3 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 ETS76124.1 - 5.5e-05 22.6 0.0 0.00016 21.1 0.0 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily Ribosomal_60s PF00428.19 ETS76124.1 - 0.015 15.8 0.1 0.049 14.2 0.1 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein Actin PF00022.19 ETS76125.1 - 1.1e-29 103.3 0.0 1.1e-18 67.1 0.0 2.6 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 ETS76125.1 - 1.2e-05 24.7 0.3 0.055 12.6 0.0 2.3 2 0 0 2 2 2 2 Putative actin-like family FtsA PF14450.6 ETS76125.1 - 0.0027 18.1 0.0 0.0097 16.3 0.0 2.0 1 1 0 1 1 1 1 Cell division protein FtsA MreB_Mbl PF06723.13 ETS76125.1 - 0.087 11.6 0.0 0.31 9.8 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein Myb_DNA-bind_6 PF13921.6 ETS76126.1 - 0.11 12.7 0.1 0.41 10.9 0.0 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain ATP_transf PF09830.9 ETS76127.1 - 7e-19 67.7 0.0 1.4e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.23 ETS76127.1 - 0.014 16.1 0.1 0.031 15.0 0.1 1.5 1 0 0 1 1 1 0 HIT domain DUF4922 PF16269.5 ETS76127.1 - 0.037 13.8 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) DUF4931 PF16285.5 ETS76127.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4931) SurE PF01975.17 ETS76128.1 - 1.6e-27 96.6 0.0 2.2e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE GATase PF00117.28 ETS76129.1 - 1.2e-08 34.9 0.2 1.7e-08 34.5 0.2 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NicO PF03824.16 ETS76130.1 - 9.5e-67 225.3 7.7 1.4e-66 224.8 7.7 1.2 1 0 0 1 1 1 1 High-affinity nickel-transport protein Peptidase_C2 PF00648.21 ETS76131.1 - 1.4e-57 195.0 0.0 3e-38 131.6 0.0 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease EF-hand_1 PF00036.32 ETS76132.1 - 1.6e-12 46.0 0.9 7.2e-10 37.7 0.4 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 ETS76132.1 - 5.4e-12 46.0 0.0 7.6e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 ETS76132.1 - 1.1e-11 44.4 0.0 1.4e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 ETS76132.1 - 5.9e-08 31.9 1.1 1.6e-05 24.2 0.3 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 ETS76132.1 - 1e-06 28.2 0.3 0.00087 19.0 0.2 2.4 1 1 1 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 ETS76132.1 - 0.0029 17.5 0.0 0.0042 17.0 0.0 1.2 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 ETS76132.1 - 0.0052 17.1 0.0 0.008 16.5 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain UPF0154 PF03672.13 ETS76132.1 - 0.022 14.7 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) MFS_1 PF07690.16 ETS76134.1 - 1.8e-33 115.9 23.8 1.8e-33 115.9 23.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS76134.1 - 8.4e-07 28.6 0.7 8.4e-07 28.6 0.7 2.7 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Amidase PF01425.21 ETS76135.1 - 6e-104 348.5 0.0 2.8e-103 346.3 0.0 1.8 1 1 0 1 1 1 1 Amidase Fungal_trans PF04082.18 ETS76136.1 - 1.4e-15 57.1 2.1 2.7e-15 56.1 2.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS76136.1 - 2.8e-08 33.7 12.7 5e-08 32.9 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5472 PF17566.2 ETS76136.1 - 0.13 12.3 0.2 0.3 11.1 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5472) RdRP PF05183.12 ETS76137.1 - 5.2e-124 415.1 0.0 9.2e-124 414.2 0.0 1.4 2 0 0 2 2 2 1 RNA dependent RNA polymerase DUF1295 PF06966.12 ETS76138.1 - 2.9e-30 105.5 0.0 4e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 ETS76138.1 - 4.1e-06 26.8 0.0 1.1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 ETS76138.1 - 0.0029 18.0 0.0 0.0059 17.0 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 ETS76138.1 - 0.037 12.8 0.0 0.09 11.5 0.0 1.6 2 0 0 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family DUF1656 PF07869.12 ETS76138.1 - 0.043 13.8 0.4 3.9 7.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) PEMT PF04191.13 ETS76138.1 - 0.063 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Phospholipid methyltransferase Clathrin PF00637.20 ETS76139.1 - 7.4e-17 61.5 1.8 7.2e-16 58.3 0.1 2.9 2 1 0 2 2 2 1 Region in Clathrin and VPS zf-RING_5 PF14634.6 ETS76139.1 - 0.001 18.9 0.9 0.0039 17.1 0.9 1.9 1 1 0 1 1 1 1 zinc-RING finger domain DUF2457 PF10446.9 ETS76139.1 - 0.0018 17.5 2.2 0.0018 17.5 2.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.10 ETS76139.1 - 0.007 16.7 4.7 0.007 16.7 4.7 2.2 2 0 0 2 2 1 1 Centromere protein B dimerisation domain C1_1 PF00130.22 ETS76139.1 - 0.074 12.9 0.6 0.16 11.9 0.6 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Vps39_1 PF10366.9 ETS76139.1 - 0.074 13.3 0.1 0.57 10.5 0.0 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_7 PF13176.6 ETS76139.1 - 0.19 11.9 1.8 0.64 10.2 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RING_11 PF17123.5 ETS76139.1 - 0.68 9.7 3.6 1.7 8.5 3.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_2 PF13639.6 ETS76139.1 - 1.1 9.6 5.0 1.6 9.2 1.1 2.4 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 ETS76139.1 - 1.3 9.1 5.1 0.43 10.6 0.7 2.2 2 0 0 2 2 2 0 RING-type zinc-finger DNA_pol_phi PF04931.13 ETS76139.1 - 4.3 5.3 14.7 6.7 4.7 14.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi ANAPC1 PF12859.7 ETS76140.1 - 9.1e-37 126.5 0.2 9.1e-37 126.5 0.2 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 ETS76140.1 - 0.024 15.1 1.5 5.3 7.7 0.1 4.2 4 0 0 4 4 4 0 Proteasome/cyclosome repeat DUF3533 PF12051.8 ETS76141.1 - 1.7e-114 382.7 17.9 2e-114 382.4 17.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.12 ETS76141.1 - 0.18 11.7 0.0 0.18 11.7 0.0 3.1 4 0 0 4 4 4 0 CDR ABC transporter Aa_trans PF01490.18 ETS76142.1 - 1.8e-23 82.9 25.1 2.2e-23 82.6 25.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RBP_receptor PF14752.6 ETS76142.1 - 0.01 14.5 1.5 0.017 13.8 1.5 1.3 1 0 0 1 1 1 1 Retinol binding protein receptor DUF2208 PF09973.9 ETS76142.1 - 0.031 13.9 1.1 0.11 12.1 0.6 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) MerC PF03203.14 ETS76142.1 - 0.21 12.0 21.5 0.16 12.4 1.8 3.4 3 1 0 3 3 3 0 MerC mercury resistance protein Peptidase_C97 PF05903.14 ETS76143.1 - 0.00071 19.4 0.1 0.0012 18.7 0.1 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Peptidase_M50B PF13398.6 ETS76143.1 - 0.03 13.9 0.1 0.057 13.1 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Peptidase_A22B PF04258.13 ETS76143.1 - 0.044 13.3 0.1 0.076 12.5 0.1 1.3 1 0 0 1 1 1 0 Signal peptide peptidase WD40 PF00400.32 ETS76145.1 - 7.9e-31 105.6 7.1 7.2e-07 29.8 0.0 7.5 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS76145.1 - 4.9e-09 36.4 0.7 0.046 14.0 0.0 5.0 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS76145.1 - 4e-06 26.0 0.0 0.22 10.5 0.0 3.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ETS76145.1 - 6.1e-05 21.9 0.5 0.75 8.4 0.0 4.4 5 0 0 5 5 5 2 Nucleoporin Nup120/160 VID27 PF08553.10 ETS76145.1 - 0.0079 15.3 0.0 0.021 13.9 0.0 1.7 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain Arena_nucleocap PF00843.17 ETS76145.1 - 0.023 13.6 3.7 2.5 6.9 0.1 3.5 2 1 2 4 4 4 0 Arenavirus nucleocapsid N-terminal domain DUF3748 PF12566.8 ETS76145.1 - 0.072 13.0 0.0 0.52 10.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3748) PilX_N PF14341.6 ETS76145.1 - 0.58 10.2 2.8 3.7 7.6 0.2 2.7 2 0 0 2 2 2 0 PilX N-terminal Glyco_hydro_31 PF01055.26 ETS76146.1 - 2.9e-89 300.3 0.1 3.7e-89 299.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 ETS76146.1 - 1.3e-10 41.4 0.0 5.7e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 ETS76146.1 - 0.045 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) EF-hand_4 PF12763.7 ETS76147.1 - 2.5e-26 91.6 0.0 9.6e-14 51.2 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 ETS76147.1 - 5.9e-05 23.4 0.0 0.091 13.2 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain pair DUF1720 PF08226.11 ETS76147.1 - 0.00012 22.4 26.9 0.00012 22.4 26.9 8.8 6 3 2 8 8 8 2 Domain of unknown function (DUF1720) EF-hand_1 PF00036.32 ETS76147.1 - 0.00035 19.9 0.0 0.36 10.5 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 ETS76147.1 - 0.0047 16.8 0.0 5.2 7.3 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain E3_binding PF02817.17 ETS76147.1 - 0.017 15.5 0.0 0.11 12.9 0.0 2.4 2 0 0 2 2 2 0 e3 binding domain CMAS PF02353.20 ETS76148.1 - 1.4e-64 218.0 0.0 1.8e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 ETS76148.1 - 3.7e-09 37.1 0.0 8.1e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS76148.1 - 4.3e-09 36.4 0.0 7.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS76148.1 - 6.5e-09 36.4 0.0 1.4e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS76148.1 - 0.0041 17.8 0.0 0.011 16.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ETS76148.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 ETS76148.1 - 0.02 14.4 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.14 ETS76148.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 ETS76148.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain G-patch_2 PF12656.7 ETS76149.1 - 7.5e-16 58.0 0.2 3.4e-15 55.9 0.2 2.2 1 0 0 1 1 1 1 G-patch domain Myb_DNA-bind_6 PF13921.6 ETS76150.1 - 3.2e-14 52.9 0.9 9.5e-14 51.4 0.9 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain HSA PF07529.13 ETS76150.1 - 4.8e-13 49.2 0.1 4.8e-13 49.2 0.1 5.9 6 0 0 6 6 6 1 HSA Myb_DNA-binding PF00249.31 ETS76150.1 - 0.00015 21.9 0.3 0.00033 20.8 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain CNOT1_HEAT PF16418.5 ETS76150.1 - 1.7 8.7 6.0 7.1 6.7 6.0 2.1 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat WD40 PF00400.32 ETS76151.1 - 4.6e-10 39.9 0.0 1.2 10.2 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS76151.1 - 1.9e-05 24.9 0.0 0.65 10.3 0.0 3.9 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Dicty_REP PF05086.12 ETS76151.1 - 0.49 8.3 2.2 0.66 7.9 2.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein INSIG PF07281.12 ETS76152.1 - 8.7e-54 182.4 0.9 1.2e-53 181.9 0.9 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) LON_substr_bdg PF02190.16 ETS76153.1 - 3.5e-28 98.9 0.0 5.6e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 ETS76153.1 - 1.3e-15 57.0 23.1 2.2e-11 43.4 12.4 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ETS76153.1 - 9.5e-13 48.1 23.7 1.5e-06 28.3 9.1 2.8 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 ETS76153.1 - 1.3e-09 38.0 22.6 2.9e-08 33.6 5.8 3.3 2 1 1 3 3 3 2 RING-type zinc-finger zf-RING_5 PF14634.6 ETS76153.1 - 2.9e-08 33.5 26.8 9e-07 28.8 11.8 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 ETS76153.1 - 3e-08 33.8 28.1 3.4e-07 30.5 12.6 2.6 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.6 ETS76153.1 - 8.7e-08 31.9 22.1 1.3e-07 31.4 8.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ETS76153.1 - 2e-07 30.8 24.5 1.5e-05 24.8 13.0 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ETS76153.1 - 2.2e-05 24.2 10.5 2.2e-05 24.2 10.5 2.5 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 ETS76153.1 - 0.00085 19.4 19.5 0.0037 17.4 6.8 2.5 2 0 0 2 2 2 2 zinc RING finger of MSL2 U-box PF04564.15 ETS76153.1 - 0.0021 18.2 0.1 0.0098 16.1 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-P11 PF03854.14 ETS76153.1 - 0.0023 17.5 6.3 0.0023 17.5 6.3 2.0 2 0 0 2 2 1 1 P-11 zinc finger zf-RING_4 PF14570.6 ETS76153.1 - 0.0048 16.7 5.6 0.0048 16.7 5.6 2.3 3 1 0 3 3 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 ETS76153.1 - 0.006 16.8 7.7 0.006 16.8 7.7 2.3 2 0 0 2 2 1 1 RING-H2 zinc finger domain UPF0556 PF10572.9 ETS76153.1 - 0.039 13.4 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0556 zf-RING_6 PF14835.6 ETS76153.1 - 0.37 10.7 16.4 0.31 10.9 4.4 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Clr5 PF14420.6 ETS76154.1 - 1e-10 41.7 0.1 2.3e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 Clr5 domain YEATS PF03366.16 ETS76156.1 - 1.1e-11 44.5 0.6 1.9e-11 43.8 0.6 1.3 1 0 0 1 1 1 1 YEATS family zf-C3HC4_4 PF15227.6 ETS76156.1 - 2.7e-06 27.4 2.8 2.7e-06 27.4 2.8 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 ETS76156.1 - 6.4e-06 25.9 3.9 6.4e-06 25.9 3.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ETS76156.1 - 9.1e-06 25.5 8.3 4.7e-05 23.2 8.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS76156.1 - 1.3e-05 25.1 2.8 1.3e-05 25.1 2.8 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ETS76156.1 - 6.9e-05 22.6 6.0 0.0023 17.8 2.6 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ETS76156.1 - 0.00016 21.9 6.9 0.00068 19.9 3.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 ETS76156.1 - 0.00022 21.1 7.3 0.0016 18.4 7.8 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_10 PF16685.5 ETS76156.1 - 0.001 19.2 5.2 0.0067 16.5 2.9 2.2 2 0 0 2 2 2 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 ETS76156.1 - 0.011 15.6 8.5 2.6 8.0 6.1 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 ETS76156.1 - 0.026 14.3 3.9 4.4 7.2 0.0 3.2 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain DUF5593 PF18007.1 ETS76156.1 - 0.077 13.7 0.0 0.17 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5593) zf-ANAPC11 PF12861.7 ETS76156.1 - 0.45 10.6 5.8 9.4 6.4 3.0 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 ETS76156.1 - 0.79 10.1 10.1 4.7 7.6 6.1 2.8 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-Nse PF11789.8 ETS76156.1 - 1.7 8.5 7.2 5.4 6.9 7.1 1.9 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF2946 PF11162.8 ETS76156.1 - 6.1 7.6 7.8 1.8 9.2 0.3 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2946) BRCT PF00533.26 ETS76158.1 - 4.3e-08 33.4 0.0 9.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ETS76158.1 - 2e-06 28.1 0.0 4.8e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 ETS76158.1 - 0.063 13.4 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 ETS76158.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Extensin_2 PF04554.13 ETS76159.1 - 8.3 6.6 14.3 27 4.9 14.3 1.9 1 1 0 1 1 1 0 Extensin-like region Helo_like_N PF17111.5 ETS76160.1 - 5e-08 32.6 0.6 1e-07 31.6 0.6 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 ETS76160.1 - 2.8e-06 27.3 0.0 8e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ETS76160.1 - 0.00033 20.9 0.0 0.003 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ETS76160.1 - 0.0076 16.8 0.0 0.02 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 ETS76160.1 - 0.0088 15.2 0.0 0.025 13.8 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain Ank_2 PF12796.7 ETS76160.1 - 0.01 16.4 0.0 0.36 11.4 0.0 3.2 4 0 0 4 4 3 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS76160.1 - 0.029 14.9 0.0 5 8.0 0.0 3.7 3 0 0 3 3 2 0 Ankyrin repeat SesA PF17107.5 ETS76160.1 - 0.033 14.4 1.4 0.065 13.4 1.4 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Bromo_TP PF07524.13 ETS76160.1 - 0.073 13.1 0.0 0.32 11.0 0.0 2.2 2 0 0 2 2 2 0 Bromodomain associated RNA_helicase PF00910.22 ETS76160.1 - 0.077 13.4 0.0 0.32 11.4 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 ETS76160.1 - 0.18 12.0 0.2 0.98 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 ETS76160.1 - 0.33 9.6 2.2 0.41 9.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ribonuc_L-PSP PF01042.21 ETS76161.1 - 2.5e-15 56.5 0.1 1.9e-14 53.7 0.1 1.9 1 1 0 1 1 1 1 Endoribonuclease L-PSP Methyltransf_24 PF13578.6 ETS76162.1 - 4.3e-12 47.0 0.0 6.9e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 ETS76162.1 - 3.5e-10 39.4 0.0 4.5e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase YadA_anchor PF03895.15 ETS76162.1 - 0.4 10.8 3.5 0.87 9.7 3.5 1.5 1 0 0 1 1 1 0 YadA-like membrane anchor domain APH PF01636.23 ETS76163.1 - 3.6e-19 69.7 0.7 5.8e-19 69.0 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 ETS76163.1 - 0.0081 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase SRP54 PF00448.22 ETS76164.1 - 2e-75 252.8 1.7 4.6e-75 251.6 0.9 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 ETS76164.1 - 3.9e-30 104.4 2.7 3.9e-30 104.4 2.7 3.3 2 1 1 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 ETS76164.1 - 2.4e-19 69.3 0.3 6.8e-19 67.9 0.3 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 ETS76164.1 - 2.9e-06 27.0 1.4 1.4e-05 24.8 0.8 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 ETS76164.1 - 4.5e-06 26.9 0.1 1.2e-05 25.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 ETS76164.1 - 2.1e-05 24.9 0.1 8.3e-05 23.0 0.1 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS76164.1 - 0.00055 20.3 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 ETS76164.1 - 0.00076 19.0 2.0 2.9 7.3 0.1 3.5 3 1 0 4 4 4 1 Signal recognition particle receptor beta subunit MeaB PF03308.16 ETS76164.1 - 0.001 18.1 2.0 0.0026 16.8 0.2 2.4 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 ETS76164.1 - 0.0014 18.4 1.5 0.0018 18.0 0.1 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ETS76164.1 - 0.0017 17.7 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin ATP_bind_1 PF03029.17 ETS76164.1 - 0.002 17.9 0.6 0.047 13.5 0.0 2.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein CbiA PF01656.23 ETS76164.1 - 0.0021 18.1 0.0 0.0076 16.3 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 ETS76164.1 - 0.0022 17.9 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 ETS76164.1 - 0.0047 17.2 0.0 0.015 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 ETS76164.1 - 0.0065 16.2 0.3 0.02 14.6 0.0 2.0 2 0 0 2 2 1 1 Thymidylate kinase MMR_HSR1 PF01926.23 ETS76164.1 - 0.0082 16.2 0.5 0.2 11.7 0.1 3.1 2 2 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 ETS76164.1 - 0.012 16.2 0.0 0.027 15.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 ETS76164.1 - 0.012 15.5 0.1 0.038 13.9 0.0 1.9 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 ETS76164.1 - 0.014 15.7 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ETS76164.1 - 0.015 15.6 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 ETS76164.1 - 0.016 15.2 0.4 0.11 12.5 0.4 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 ETS76164.1 - 0.035 13.0 0.1 0.086 11.7 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain 6PF2K PF01591.18 ETS76164.1 - 0.038 13.3 0.0 0.082 12.2 0.0 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Arf PF00025.21 ETS76164.1 - 0.069 12.6 0.0 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_24 PF13479.6 ETS76164.1 - 0.075 12.8 0.1 0.37 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ETS76164.1 - 0.094 13.1 0.2 0.38 11.2 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKA2 PF16740.5 ETS76164.1 - 0.18 11.6 2.1 6.1 6.7 1.6 2.6 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 T3SS_basalb_I PF17001.5 ETS76164.1 - 6.1 7.5 12.8 1.2 9.8 0.1 3.3 3 0 0 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI AA_permease PF00324.21 ETS76165.1 - 1.7e-30 106.1 29.6 1.6e-29 102.9 29.6 2.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS76165.1 - 1.2e-14 54.0 25.5 1.9e-14 53.4 25.5 1.3 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 ETS76165.1 - 0.17 10.7 9.6 0.095 11.5 0.5 3.3 4 0 0 4 4 4 0 Spore germination protein Pkinase PF00069.25 ETS76166.1 - 3.8e-15 56.0 0.0 8.9e-15 54.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS76166.1 - 9.8e-14 51.2 0.0 1.7e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 ETS76166.1 - 0.16 10.9 0.1 0.27 10.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cellulase PF00150.18 ETS76167.1 - 3.6e-50 171.0 2.2 4.4e-50 170.7 2.2 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.25 ETS76168.1 - 2.4e-41 141.8 0.0 3.2e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS76168.1 - 1.6e-22 80.1 0.0 2.2e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase BAG PF02179.16 ETS76168.1 - 4.8e-08 33.3 0.0 8.9e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 BAG domain Kdo PF06293.14 ETS76168.1 - 0.00011 21.6 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ETS76168.1 - 0.096 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 ETS76168.1 - 0.18 10.5 0.0 0.48 9.1 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Pkinase_Tyr PF07714.17 ETS76169.1 - 0.00043 19.7 0.0 0.039 13.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 ETS76169.1 - 0.0017 17.8 0.0 0.0047 16.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Git3 PF11710.8 ETS76171.1 - 6.3e-23 81.6 13.7 1.6e-22 80.3 13.7 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 ETS76171.1 - 0.00031 20.7 1.2 0.00046 20.2 0.0 1.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 ETS76171.1 - 0.0093 15.1 11.3 0.015 14.5 11.3 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Glyco_hydro_31 PF01055.26 ETS76172.1 - 8.5e-129 430.6 4.4 1.1e-128 430.2 4.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 ETS76172.1 - 9.7e-30 103.1 0.0 1.8e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase zf-C2H2_assoc PF16606.5 ETS76172.1 - 0.45 10.8 3.6 0.43 10.8 0.2 2.3 2 0 0 2 2 2 0 Unstructured conserved, between two C2H2-type zinc-fingers Rpp20 PF12328.8 ETS76173.1 - 0.053 13.5 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Ribonucleas_3_3 PF14622.6 ETS76173.1 - 0.13 12.4 0.5 0.26 11.4 0.1 1.7 2 0 0 2 2 2 0 Ribonuclease-III-like Exo_endo_phos PF03372.23 ETS76174.1 - 2.7e-07 30.4 0.2 3.6e-07 30.0 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_transf_15 PF01793.16 ETS76175.1 - 7e-87 291.7 5.9 1e-86 291.2 5.9 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Gly_transf_sug PF04488.15 ETS76176.1 - 4.6e-08 33.6 0.0 1.1e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ETS76176.1 - 0.00028 20.4 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 ETS76176.1 - 0.0024 17.2 0.0 0.0055 16.0 0.0 1.5 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain HET PF06985.11 ETS76177.1 - 9e-22 78.0 0.0 1.8e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PCYCGC PF13798.6 ETS76177.1 - 0.15 11.9 0.1 1 9.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function with PCYCGC motif MFS_1 PF07690.16 ETS76179.1 - 2.6e-37 128.6 22.5 2.6e-37 128.6 22.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily HpcH_HpaI PF03328.14 ETS76180.1 - 8.8e-34 116.6 0.3 1.1e-33 116.3 0.3 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 ETS76180.1 - 0.0015 17.7 0.1 0.067 12.3 0.1 2.5 1 1 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain Ribonuc_L-PSP PF01042.21 ETS76181.1 - 2.7e-22 79.0 0.0 3.4e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF5130 PF17174.4 ETS76181.1 - 0.0058 16.8 0.0 0.0068 16.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5130) 2OG-FeII_Oxy PF03171.20 ETS76182.1 - 2.5e-11 44.0 0.0 4.5e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ETS76182.1 - 7.8e-10 39.5 0.0 1.7e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Fungal_trans PF04082.18 ETS76183.1 - 8.7e-22 77.4 0.6 8.7e-22 77.4 0.6 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 ETS76183.1 - 6.4e-06 26.3 12.1 0.011 16.1 1.4 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS76183.1 - 1.9e-05 25.1 9.1 0.013 16.2 0.9 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ETS76183.1 - 0.0012 19.2 3.3 0.43 11.0 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ETS76183.1 - 0.0056 17.1 6.5 0.13 12.7 0.0 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ETS76183.1 - 0.042 14.1 1.9 2.4 8.5 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 ETS76183.1 - 0.12 12.3 1.2 0.28 11.1 1.2 1.6 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2H2_2 PF12756.7 ETS76183.1 - 1 9.7 5.9 9.5 6.6 0.6 2.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF4686 PF15742.5 ETS76184.1 - 0.00012 21.4 12.1 0.00017 20.9 12.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) Exonuc_VII_L PF02601.15 ETS76184.1 - 0.0046 16.6 4.2 0.0051 16.4 4.2 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit Lebercilin PF15619.6 ETS76184.1 - 0.0061 16.2 11.7 0.0094 15.6 11.7 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease YkyA PF10368.9 ETS76184.1 - 0.013 15.2 6.2 0.019 14.6 6.2 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein MSA-2c PF12238.8 ETS76184.1 - 0.031 14.3 5.8 0.027 14.5 3.8 1.9 2 1 1 3 3 3 0 Merozoite surface antigen 2c Nsp1_C PF05064.13 ETS76184.1 - 0.031 14.1 3.5 0.051 13.4 3.5 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region BST2 PF16716.5 ETS76184.1 - 0.036 14.7 8.8 1.5 9.5 1.8 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF745 PF05335.13 ETS76184.1 - 0.13 12.0 6.7 0.21 11.3 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) TMPIT PF07851.13 ETS76184.1 - 0.18 11.0 6.7 0.25 10.5 6.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein TMF_DNA_bd PF12329.8 ETS76184.1 - 0.26 11.3 12.5 2.3 8.3 5.7 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 ETS76184.1 - 0.31 10.4 4.7 0.33 10.3 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 ETS76184.1 - 0.36 9.9 8.6 0.47 9.5 8.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OEP PF02321.18 ETS76184.1 - 0.63 9.8 5.5 16 5.3 2.9 2.1 2 0 0 2 2 2 0 Outer membrane efflux protein DUF16 PF01519.16 ETS76184.1 - 1.3 9.5 12.6 3.4 8.2 12.6 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 SlyX PF04102.12 ETS76184.1 - 2.8 8.6 7.9 3.3 8.4 3.6 2.6 1 1 1 2 2 2 0 SlyX DUF2570 PF10828.8 ETS76184.1 - 3.1 7.6 10.4 8.6 6.2 10.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Rotamase PF00639.21 ETS76184.1 - 4.8 8.2 6.8 13 6.9 0.6 2.5 1 1 1 2 2 2 0 PPIC-type PPIASE domain Amidohydro_2 PF04909.14 ETS76185.1 - 2.2e-39 136.0 0.6 3.1e-39 135.5 0.6 1.2 1 0 0 1 1 1 1 Amidohydrolase SnoaL_2 PF12680.7 ETS76186.1 - 0.0076 16.9 0.1 0.011 16.4 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain Hydrolase_4 PF12146.8 ETS76187.1 - 2.9e-20 72.6 0.1 8.2e-20 71.1 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS76187.1 - 2.6e-17 64.2 0.0 3.2e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS76187.1 - 1.3e-12 47.9 1.5 3e-07 30.3 0.6 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS76187.1 - 5.6e-06 26.0 0.1 0.064 12.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family LIP PF03583.14 ETS76187.1 - 0.00073 19.0 0.0 0.0013 18.1 0.0 1.4 1 1 0 1 1 1 1 Secretory lipase Ser_hydrolase PF06821.13 ETS76187.1 - 0.00078 19.3 0.1 0.14 12.0 0.1 2.3 1 1 0 1 1 1 1 Serine hydrolase Thioesterase PF00975.20 ETS76187.1 - 0.0012 19.0 0.2 0.0073 16.4 0.1 1.9 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_2 PF02230.16 ETS76187.1 - 0.0017 18.2 0.3 5.7 6.7 0.1 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DLH PF01738.18 ETS76187.1 - 0.0025 17.4 0.0 0.19 11.2 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family DUF1057 PF06342.12 ETS76187.1 - 0.0026 16.8 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Chlorophyllase2 PF12740.7 ETS76187.1 - 0.0077 15.2 0.2 0.013 14.4 0.2 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 ETS76187.1 - 0.015 13.8 2.5 0.75 8.3 1.0 2.2 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.13 ETS76187.1 - 0.044 13.5 0.6 0.33 10.7 0.1 2.1 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_4 PF08386.10 ETS76187.1 - 0.049 13.7 0.0 0.14 12.3 0.0 1.7 1 1 0 1 1 1 0 TAP-like protein Abhydrolase_5 PF12695.7 ETS76187.1 - 0.1 12.3 0.1 2.5 7.8 0.0 2.4 3 0 0 3 3 3 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 ETS76187.1 - 0.12 11.9 0.0 1.4 8.4 0.1 2.0 1 1 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 ETS76187.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold CoA_transf_3 PF02515.17 ETS76189.1 - 1e-40 140.0 0.0 1.3e-38 133.1 0.0 2.3 2 0 0 2 2 2 2 CoA-transferase family III UPF0262 PF06793.12 ETS76189.1 - 0.026 14.6 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) Dioxygenase_C PF00775.21 ETS76190.1 - 6.2e-46 156.1 0.0 8.4e-46 155.7 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 ETS76190.1 - 8.8e-29 99.2 0.1 1.4e-28 98.5 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 ETS76190.1 - 7.6e-07 29.3 0.0 7.2e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.9 ETS76190.1 - 0.00075 19.9 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) SpaA PF17802.1 ETS76190.1 - 0.0022 18.3 0.0 0.014 15.7 0.0 2.0 2 0 0 2 2 2 1 Prealbumin-like fold domain RHH_8 PF17723.1 ETS76190.1 - 0.0057 16.8 0.0 0.0087 16.2 0.0 1.2 1 0 0 1 1 1 1 Ribbon-Helix-Helix transcriptional regulator family CarbopepD_reg_2 PF13715.6 ETS76190.1 - 0.032 14.2 0.0 6.9 6.7 0.0 2.8 2 0 0 2 2 2 0 CarboxypepD_reg-like domain TTR-52 PF01060.23 ETS76190.1 - 0.075 13.7 0.0 0.18 12.5 0.0 1.7 1 0 0 1 1 1 0 Transthyretin-like family DEAD PF00270.29 ETS76191.1 - 3.1e-42 144.3 0.2 5.1e-42 143.6 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS76191.1 - 2.6e-33 114.7 0.0 9.7e-33 112.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 ETS76191.1 - 0.00039 20.2 0.1 0.00059 19.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 ETS76191.1 - 0.00058 19.9 0.0 0.0012 18.9 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ETS76191.1 - 0.0011 19.3 0.1 0.0089 16.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 ETS76191.1 - 0.046 13.1 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Flavi_DEAD PF07652.14 ETS76191.1 - 0.055 13.4 0.5 0.18 11.8 0.0 2.1 3 1 0 3 3 3 0 Flavivirus DEAD domain DUF5393 PF17371.2 ETS76191.1 - 0.06 11.5 0.1 0.095 10.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) Helicase_RecD PF05127.14 ETS76191.1 - 0.086 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 ETS76191.1 - 0.13 12.6 1.0 0.58 10.4 1.0 2.0 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.8 ETS76192.1 - 1.2e-76 256.6 0.1 1.2e-76 256.6 0.1 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 ETS76192.1 - 7.5e-26 90.5 0.4 7.5e-26 90.5 0.4 1.8 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 ETS76192.1 - 2e-12 46.7 0.0 4.7e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 ETS76192.1 - 1.9e-09 37.6 2.5 1.4e-07 31.7 1.2 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ETS76192.1 - 3.8e-09 36.6 2.2 3.8e-09 36.6 2.2 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ETS76192.1 - 0.00022 21.5 0.0 0.0048 17.2 0.0 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) PRP9_N PF16958.5 ETS76192.1 - 0.014 15.5 15.6 0.063 13.3 0.7 3.3 4 1 1 5 5 5 0 Pre-mRNA-splicing factor PRP9 N-terminus zf-DBF PF07535.12 ETS76192.1 - 0.018 15.1 0.8 0.018 15.1 0.8 2.9 3 1 0 3 3 3 0 DBF zinc finger zf-C2H2_4 PF13894.6 ETS76192.1 - 0.033 15.0 1.1 5.7 8.1 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Pox_P21 PF05313.12 ETS76192.1 - 0.084 12.4 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein zf-U1 PF06220.12 ETS76192.1 - 0.13 12.0 0.8 0.32 10.8 0.8 1.6 1 0 0 1 1 1 0 U1 zinc finger DUF4407 PF14362.6 ETS76192.1 - 1.7 7.9 7.2 0.24 10.7 3.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AtuA PF07287.11 ETS76193.1 - 6.7e-126 419.7 0.1 8.2e-126 419.4 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA ADH_zinc_N PF00107.26 ETS76195.1 - 4.3e-15 55.8 0.0 8.5e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS76195.1 - 1.7e-09 38.8 0.0 6.1e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS76195.1 - 9.3e-08 31.9 0.1 2.2e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain THF_DHG_CYH_C PF02882.19 ETS76195.1 - 0.034 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain COG2 PF06148.11 ETS76196.1 - 6.2e-25 87.8 0.3 1.2e-24 86.9 0.3 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 ETS76196.1 - 0.00022 21.2 3.7 0.00027 20.9 0.1 2.8 2 1 1 3 3 3 1 Vps51/Vps67 COG5 PF10392.9 ETS76196.1 - 0.024 14.8 0.6 0.078 13.2 0.1 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Spc7 PF08317.11 ETS76196.1 - 0.038 12.9 2.0 0.039 12.8 0.4 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein DLP_helical PF18709.1 ETS76196.1 - 0.072 12.3 0.2 0.35 10.0 0.1 2.0 2 0 0 2 2 2 0 Dynamin-like helical domain Zw10 PF06248.13 ETS76196.1 - 0.099 11.2 0.1 0.14 10.7 0.1 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Cytochrom_B562 PF07361.11 ETS76196.1 - 0.1 13.3 1.4 0.29 11.8 0.1 2.4 2 2 1 3 3 3 0 Cytochrome b562 Vps54_N PF10475.9 ETS76196.1 - 0.12 11.6 0.0 0.48 9.6 0.0 1.9 1 1 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Cwf_Cwc_15 PF04889.12 ETS76196.1 - 0.67 9.6 8.6 0.18 11.5 5.0 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF3246 PF11596.8 ETS76196.1 - 0.95 8.8 5.2 0.63 9.4 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Hap4_Hap_bind PF10297.9 ETS76197.1 - 5.5e-09 35.9 6.9 1.3e-08 34.6 6.9 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 ETS76197.1 - 0.00026 21.0 13.0 0.00099 19.2 5.9 2.8 1 1 1 2 2 2 1 bZIP transcription factor CENP-F_leu_zip PF10473.9 ETS76197.1 - 0.00092 19.3 11.3 0.0078 16.2 6.4 2.2 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC144C PF14915.6 ETS76197.1 - 0.0071 15.5 4.0 0.012 14.7 4.0 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region HMMR_N PF15905.5 ETS76197.1 - 0.0081 15.7 6.3 0.0081 15.7 6.3 1.9 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal Striatin PF08232.12 ETS76197.1 - 0.012 16.3 6.7 1.3 9.6 4.5 2.5 2 0 0 2 2 2 0 Striatin family Fer2_2 PF01799.20 ETS76197.1 - 0.017 15.2 2.9 0.1 12.6 0.2 2.8 2 0 0 2 2 2 0 [2Fe-2S] binding domain Baculo_PEP_C PF04513.12 ETS76197.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus dsrm PF00035.26 ETS76197.1 - 0.12 13.1 0.0 0.35 11.6 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif Spc7 PF08317.11 ETS76197.1 - 0.2 10.5 4.7 0.34 9.8 4.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein SKA1 PF07160.12 ETS76197.1 - 0.31 10.8 6.5 0.034 14.0 1.2 1.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Exonuc_VII_L PF02601.15 ETS76197.1 - 0.33 10.5 2.4 0.47 10.0 2.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 ETS76197.1 - 0.88 8.6 9.0 2.3 7.2 9.1 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HrpB7 PF09486.10 ETS76197.1 - 1.1 9.7 15.4 0.7 10.3 5.8 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) TEX13 PF15186.6 ETS76197.1 - 1.6 8.4 7.6 3.3 7.4 7.6 1.5 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family LURAP PF14854.6 ETS76197.1 - 1.9 8.4 5.2 0.32 11.0 1.0 1.9 2 0 0 2 2 2 0 Leucine rich adaptor protein DUF2066 PF09839.9 ETS76198.1 - 0.0094 15.4 0.1 0.092 12.1 0.1 1.9 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2066) SPT6_acidic PF14632.6 ETS76198.1 - 0.039 14.5 0.6 0.076 13.6 0.6 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 FAD_binding_4 PF01565.23 ETS76200.1 - 1.7e-19 69.9 1.7 5.7e-19 68.2 1.7 2.0 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS76200.1 - 3.7e-10 39.8 2.2 7.4e-10 38.8 1.6 1.9 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 ETS76200.1 - 0.0027 17.1 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding BPL_LplA_LipB PF03099.19 ETS76200.1 - 0.057 13.3 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family APOBEC_C PF05240.14 ETS76201.1 - 0.081 12.9 0.1 0.33 10.9 0.1 1.9 2 0 0 2 2 2 0 APOBEC-like C-terminal domain Helo_like_N PF17111.5 ETS76202.1 - 0.00026 20.4 4.2 0.00029 20.2 0.2 1.9 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins DHR10 PF18595.1 ETS76202.1 - 0.095 12.8 11.3 0.18 11.8 11.4 1.4 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain TRPM_tetra PF16519.5 ETS76202.1 - 0.098 12.8 0.4 0.098 12.8 0.4 2.1 2 0 0 2 2 2 0 Tetramerisation domain of TRPM FUSC PF04632.12 ETS76202.1 - 0.16 10.5 3.3 0.19 10.2 3.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family RIC3 PF15361.6 ETS76202.1 - 0.18 12.2 4.6 0.19 12.1 3.9 1.3 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 MCC-bdg_PDZ PF10506.9 ETS76202.1 - 4.1 7.5 11.1 4.6 7.3 1.5 3.4 3 1 1 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Med9 PF07544.13 ETS76202.1 - 5.3 7.2 9.4 43 4.3 6.1 2.9 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Syntaxin_2 PF14523.6 ETS76203.1 - 0.57 10.6 5.3 1.3 9.5 1.4 2.3 2 0 0 2 2 2 0 Syntaxin-like protein Ank PF00023.30 ETS76204.1 - 0.019 15.4 0.2 0.12 12.9 0.1 2.4 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 ETS76204.1 - 0.056 14.0 0.0 0.29 11.7 0.0 2.2 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) MMS22L_N PF14910.6 ETS76204.1 - 0.22 9.9 0.1 0.33 9.3 0.1 1.2 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal Zn_clus PF00172.18 ETS76205.1 - 1.2e-05 25.3 11.1 2.8e-05 24.2 11.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS76205.1 - 0.011 14.6 0.0 0.026 13.4 0.0 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain PAC4 PF16093.5 ETS76205.1 - 0.2 11.8 4.6 0.52 10.5 0.1 3.1 3 0 0 3 3 3 0 Proteasome assembly chaperone 4 PAP1 PF08601.10 ETS76205.1 - 0.29 10.8 4.7 0.47 10.1 4.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 adh_short PF00106.25 ETS76206.1 - 1e-37 129.5 0.0 1.3e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS76206.1 - 5e-21 75.3 0.0 6.3e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS76206.1 - 2.2e-07 30.9 0.1 3.4e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS76206.1 - 0.00022 20.8 0.1 0.00087 18.8 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ETS76206.1 - 0.011 15.9 0.1 0.023 15.0 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ETS76206.1 - 0.038 14.0 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 ETS76206.1 - 0.075 12.4 0.1 0.13 11.6 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF5631 PF18645.1 ETS76206.1 - 0.077 13.4 0.0 0.63 10.5 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5631) 3HCDH_N PF02737.18 ETS76206.1 - 0.1 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M3 PF01432.20 ETS76207.1 - 1.5e-99 334.3 2.5 2.2e-99 333.8 2.5 1.1 1 0 0 1 1 1 1 Peptidase family M3 CN_hydrolase PF00795.22 ETS76208.1 - 8.3e-14 51.5 0.0 9.2e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GCD14 PF08704.10 ETS76209.1 - 0.073 12.7 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit GST_C PF00043.25 ETS76210.1 - 9.2e-11 41.8 0.0 1.8e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ETS76210.1 - 4.6e-10 39.7 0.0 1e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ETS76210.1 - 3.6e-09 36.7 0.0 6.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ETS76210.1 - 1.4e-07 31.7 0.0 3.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ETS76210.1 - 2.2e-06 28.0 0.0 4.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS76210.1 - 1.3e-05 25.1 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NACHT PF05729.12 ETS76211.1 - 6e-09 36.0 0.0 1.4e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS76211.1 - 1.5e-07 32.0 0.0 5.7e-07 30.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS76211.1 - 1.1e-05 25.7 0.0 3.6e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETS76211.1 - 0.00016 22.2 0.0 0.00043 20.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ETS76211.1 - 0.0058 17.1 0.0 0.016 15.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 ETS76211.1 - 0.017 14.9 0.1 0.037 13.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 ETS76211.1 - 0.071 13.5 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 ETS76211.1 - 0.078 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ploopntkinase1 PF18748.1 ETS76211.1 - 0.11 12.1 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 NTPase_1 PF03266.15 ETS76211.1 - 0.16 11.9 0.3 0.4 10.6 0.1 1.8 2 0 0 2 2 2 0 NTPase Viral_helicase1 PF01443.18 ETS76211.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Ytp1 PF10355.9 ETS76212.1 - 1.6e-68 230.9 21.5 1.6e-68 230.9 21.5 2.5 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 ETS76212.1 - 3.7e-32 110.2 0.9 3.7e-32 110.2 0.9 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Sbt_1 PF05982.12 ETS76212.1 - 0.075 12.3 5.4 0.023 13.9 1.2 2.1 2 0 0 2 2 2 0 Na+-dependent bicarbonate transporter superfamily Glyco_hydro_43 PF04616.14 ETS76213.1 - 2e-32 112.7 8.7 2.4e-32 112.4 8.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 LRR_10 PF18805.1 ETS76213.1 - 0.016 14.8 0.3 0.04 13.6 0.1 1.7 2 0 0 2 2 2 0 Leucine-rich repeat FMN_dh PF01070.18 ETS76214.1 - 9.3e-107 357.0 0.0 1.1e-106 356.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ETS76214.1 - 0.0001 21.4 0.6 0.00019 20.5 0.6 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ETS76214.1 - 0.00022 20.5 0.3 0.00033 19.9 0.3 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 ETS76214.1 - 0.0022 17.5 0.2 0.022 14.3 0.1 2.1 1 1 1 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 ETS76214.1 - 0.025 14.0 0.5 0.037 13.4 0.5 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.14 ETS76214.1 - 0.028 13.7 0.6 4.3 6.6 0.1 2.3 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG ThrE PF06738.12 ETS76215.1 - 1.3e-69 234.2 16.9 6.8e-65 218.8 3.6 2.4 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ETS76215.1 - 4.4e-11 43.0 11.1 4.4e-11 43.0 11.1 2.5 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE NMN_transporter PF04973.12 ETS76215.1 - 0.043 13.8 6.1 0.54 10.2 6.1 2.2 1 1 0 1 1 1 0 Nicotinamide mononucleotide transporter DSBA PF01323.20 ETS76216.1 - 1.1e-39 136.2 0.0 1.3e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 ETS76216.1 - 8.8e-05 22.7 0.0 0.00015 21.9 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_5 PF13743.6 ETS76216.1 - 0.00015 21.5 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 ETS76216.1 - 0.012 15.7 0.3 0.16 12.1 0.1 2.4 2 1 0 2 2 2 0 Thioredoxin domain Glutaredoxin PF00462.24 ETS76216.1 - 0.089 13.0 0.2 0.93 9.8 0.0 2.5 2 1 0 2 2 2 0 Glutaredoxin Thioredoxin_2 PF13098.6 ETS76216.1 - 0.1 13.1 0.1 0.2 12.1 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin-like domain Acetyltransf_3 PF13302.7 ETS76217.1 - 5.5e-12 46.5 0.0 8.6e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS76217.1 - 7.4e-12 45.5 0.0 9.7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 ETS76217.1 - 8.5e-07 29.2 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS76217.1 - 4.1e-05 23.9 0.0 5.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS76217.1 - 0.00084 19.3 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ETS76217.1 - 0.0012 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS76217.1 - 0.024 14.6 0.2 0.074 13.0 0.1 1.9 2 1 0 2 2 2 0 FR47-like protein Glyco_hydro_79C PF16862.5 ETS76218.1 - 2.1e-14 54.2 0.1 4.3e-14 53.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain PLU-1 PF08429.11 ETS76219.1 - 9.2e-116 386.7 13.8 1.6e-113 379.3 11.8 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 ETS76219.1 - 1.7e-41 141.2 0.3 4.3e-41 139.9 0.3 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 ETS76219.1 - 1.7e-21 76.7 0.0 4.2e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 ETS76219.1 - 2e-15 56.4 30.7 3.5e-08 33.2 3.5 3.7 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.17 ETS76219.1 - 1.4e-12 47.3 0.4 3.3e-12 46.1 0.4 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 ETS76219.1 - 3.1e-11 43.5 9.8 7.5e-11 42.3 9.8 1.7 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.6 ETS76219.1 - 0.025 14.2 7.4 0.16 11.6 0.7 2.9 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain GIY-YIG PF01541.24 ETS76220.1 - 3.4e-12 46.5 0.0 7.7e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H PF13771.6 ETS76220.1 - 8.9e-06 25.9 1.1 1.6e-05 25.1 1.1 1.3 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 ETS76220.1 - 4.2e-05 23.7 1.1 7e-05 23.0 1.1 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain FANCL_C PF11793.8 ETS76220.1 - 0.0074 16.4 2.7 0.013 15.6 2.7 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain Peptidase_M28 PF04389.17 ETS76221.1 - 6.2e-28 97.8 0.3 9.9e-28 97.2 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M28 DUF2891 PF11199.8 ETS76221.1 - 0.031 13.2 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) Peptidase_M20 PF01546.28 ETS76221.1 - 0.093 12.4 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 MEDS PF14417.6 ETS76222.1 - 0.018 14.9 2.3 1.2 9.0 0.0 2.6 2 1 1 3 3 3 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Abhydrolase_1 PF00561.20 ETS76223.1 - 3.3e-17 63.0 0.0 8.5e-17 61.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 ETS76223.1 - 3.9e-17 62.3 0.0 7.9e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein tRNA-synt_1c PF00749.21 ETS76224.1 - 6.9e-103 343.8 0.0 9.5e-103 343.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 ETS76224.1 - 2.5e-41 141.5 0.1 3.9e-41 140.8 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Ribosomal_L1 PF00687.21 ETS76225.1 - 1.8e-20 73.6 0.2 2.3e-20 73.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family HET PF06985.11 ETS76226.1 - 1.2e-25 90.5 0.0 9.1e-25 87.7 0.0 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_4 PF08386.10 ETS76227.1 - 1.5e-20 73.3 0.0 4.8e-20 71.6 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 ETS76227.1 - 7.7e-20 71.6 0.1 3.8e-17 62.8 0.1 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Fungal_trans_2 PF11951.8 ETS76228.1 - 1.8e-07 30.4 0.2 1.6e-06 27.2 0.0 2.1 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS76228.1 - 2.2e-07 30.9 6.3 4.2e-07 30.0 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AID PF18767.1 ETS76229.1 - 0.019 15.0 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Activation induced deaminase Phenol_monoox PF04663.12 ETS76229.1 - 0.17 12.0 0.0 3 8.1 0.0 2.2 2 0 0 2 2 2 0 Phenol hydroxylase conserved region adh_short_C2 PF13561.6 ETS76230.1 - 4.9e-42 144.1 0.7 7.4e-42 143.5 0.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS76230.1 - 5e-39 133.8 0.2 8.7e-39 133.0 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS76230.1 - 4.2e-09 36.6 0.1 7e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS76230.1 - 0.01 15.3 0.1 0.04 13.4 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family LDcluster4 PF18306.1 ETS76230.1 - 0.039 13.6 0.1 0.074 12.6 0.1 1.4 1 0 0 1 1 1 0 SLOG cluster4 family GDP_Man_Dehyd PF16363.5 ETS76230.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Redoxin PF08534.10 ETS76231.1 - 4.4e-37 127.0 0.0 4.9e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ETS76231.1 - 1.2e-09 38.2 0.0 1.5e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF123 PF01986.16 ETS76232.1 - 0.086 13.4 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF123 Fungal_trans PF04082.18 ETS76234.1 - 0.00014 21.0 0.4 0.0003 19.9 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS76234.1 - 0.00068 19.7 9.4 0.0015 18.6 9.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ETS76235.1 - 4.2e-39 134.5 50.5 3.6e-38 131.4 49.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2919 PF11143.8 ETS76235.1 - 0.29 11.4 6.1 1 9.7 2.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) Lipase_GDSL PF00657.22 ETS76236.1 - 8.7e-06 25.8 0.0 1e-05 25.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ETS76236.1 - 0.0051 17.2 4.6 0.0068 16.8 4.6 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PLATZ PF04640.14 ETS76237.1 - 0.17 12.5 0.0 0.28 11.9 0.0 1.3 1 0 0 1 1 1 0 PLATZ transcription factor adh_short PF00106.25 ETS76238.1 - 2.6e-10 40.1 0.0 3.5e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS76238.1 - 1.4e-05 25.1 0.1 3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 KR domain Lactonase PF10282.9 ETS76239.1 - 5.7e-59 200.1 0.0 7.5e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller p450 PF00067.22 ETS76240.1 - 1.9e-57 195.1 0.0 2.6e-57 194.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_3 PF13302.7 ETS76241.1 - 3.8e-17 63.3 0.0 5.6e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS76241.1 - 4.9e-05 23.5 0.0 0.00045 20.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS76241.1 - 0.043 14.2 0.0 0.064 13.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS76241.1 - 0.044 13.7 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS76241.1 - 0.082 12.9 0.0 0.84 9.6 0.0 2.2 1 1 1 2 2 2 0 FR47-like protein MFS_1 PF07690.16 ETS76244.1 - 6.3e-34 117.4 51.5 2.9e-30 105.4 28.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS76244.1 - 6.2e-11 41.8 17.5 8.5e-10 38.1 17.5 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Methyltransf_2 PF00891.18 ETS76245.1 - 9.1e-20 70.9 0.0 1.6e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 ETS76245.1 - 0.079 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase COesterase PF00135.28 ETS76246.1 - 6.5e-85 285.9 0.1 9.4e-85 285.4 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS76246.1 - 1.2e-05 25.2 0.1 7.7e-05 22.6 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold CM_2 PF01817.21 ETS76247.1 - 0.011 16.0 0.4 0.057 13.8 0.2 2.0 2 0 0 2 2 2 0 Chorismate mutase type II Helicase_C PF00271.31 ETS76248.1 - 1.2e-09 38.5 0.0 2.6e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 ETS76248.1 - 9.3e-06 25.9 0.7 2.8e-05 24.3 0.1 2.2 2 1 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ETS76248.1 - 4.8e-05 23.6 0.0 0.00013 22.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Caenor_Her-1 PF09232.10 ETS76249.1 - 0.096 12.8 0.4 0.14 12.3 0.4 1.3 1 0 0 1 1 1 0 Caenorhabditis elegans Her-1 Transcript_VP30 PF11507.8 ETS76250.1 - 0.014 15.5 0.1 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 Ebola virus-specific transcription factor VP30 Arf PF00025.21 ETS76251.1 - 6.5e-68 227.6 1.8 7.2e-68 227.5 1.8 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ETS76251.1 - 6.6e-13 48.9 0.1 9.5e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ETS76251.1 - 8.6e-13 48.2 0.0 1e-12 48.0 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 ETS76251.1 - 1e-12 47.9 1.0 2.7e-07 30.1 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 ETS76251.1 - 4.5e-10 39.3 0.1 5.4e-10 39.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ETS76251.1 - 2.3e-08 34.1 0.0 3.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 ETS76251.1 - 3.1e-08 33.2 0.0 3.7e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 ETS76251.1 - 0.00033 20.3 0.0 0.0086 15.6 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 ETS76251.1 - 0.0038 17.1 0.2 0.073 13.0 0.0 2.1 2 0 0 2 2 2 1 NACHT domain FeoB_N PF02421.18 ETS76251.1 - 0.08 12.5 0.3 0.21 11.1 0.3 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.18 ETS76251.1 - 0.11 11.8 0.1 0.21 10.8 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF4045 PF13254.6 ETS76252.1 - 4.9e-94 316.3 32.6 5e-59 201.0 23.0 6.1 3 3 1 4 4 4 2 Domain of unknown function (DUF4045) Gelsolin PF00626.22 ETS76252.1 - 1.5e-08 34.5 0.1 0.00035 20.4 0.0 3.3 4 0 0 4 4 4 2 Gelsolin repeat DUF3894 PF13033.6 ETS76252.1 - 0.23 11.6 0.4 0.41 10.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3894) Acyl-CoA_dh_2 PF08028.11 ETS76254.1 - 1.4e-13 51.2 1.6 2.4e-13 50.5 1.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ETS76254.1 - 2.8e-06 27.5 0.3 8.5e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ETS76254.1 - 5.6e-06 27.0 0.1 1.4e-05 25.8 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ETS76254.1 - 0.0021 18.3 0.3 0.0044 17.2 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Methyltransf_25 PF13649.6 ETS76255.1 - 3.9e-13 49.9 0.0 7.2e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS76255.1 - 2.6e-12 47.2 0.0 4.5e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS76255.1 - 5.3e-11 42.3 0.0 9.8e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ETS76255.1 - 6.2e-06 26.1 0.0 8.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS76255.1 - 3.8e-05 24.3 0.0 6.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 ETS76255.1 - 0.23 10.0 0.1 2.5 6.5 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase S1-P1_nuclease PF02265.16 ETS76256.1 - 6.4e-68 229.3 0.0 7.4e-68 229.1 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PDEase_II PF02112.15 ETS76257.1 - 1.3e-54 185.6 0.0 2.8e-45 154.9 0.0 3.0 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 ETS76257.1 - 0.018 14.5 0.2 0.13 11.7 0.2 2.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain AMP-binding PF00501.28 ETS76259.1 - 1.1e-66 225.2 0.1 1e-34 119.9 0.0 4.3 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 ETS76259.1 - 2.2e-11 44.5 0.0 4.9e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 ETS76259.1 - 0.0002 21.3 0.6 0.00049 20.0 0.6 1.6 1 0 0 1 1 1 1 Gas vesicle protein G Zn_clus PF00172.18 ETS76260.1 - 5.1e-09 36.1 6.3 8.4e-09 35.4 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VWA_N2 PF16164.5 ETS76260.1 - 0.11 12.6 2.3 0.25 11.5 2.3 1.5 1 0 0 1 1 1 0 VWA N-terminal FMO-like PF00743.19 ETS76261.1 - 7.8e-59 199.5 0.0 1.4e-58 198.6 0.0 1.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ETS76261.1 - 2.8e-10 40.0 0.0 3.1e-07 30.0 0.1 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS76261.1 - 2.6e-08 34.0 0.0 6.6e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS76261.1 - 1.1e-07 31.5 0.0 4.7e-05 22.8 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS76261.1 - 4.4e-07 29.8 0.5 0.042 13.4 0.1 2.8 2 1 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 ETS76261.1 - 5.7e-06 25.7 0.8 1.6e-05 24.2 0.0 2.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ETS76261.1 - 0.00054 20.0 0.1 0.047 13.7 0.2 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 ETS76261.1 - 0.0013 19.3 0.0 0.24 12.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS76261.1 - 0.0044 15.8 0.1 0.007 15.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 ETS76261.1 - 0.014 14.7 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 ETS76261.1 - 0.032 13.5 0.0 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain SipA_VBS PF17985.1 ETS76261.1 - 0.064 13.2 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 SipA vinculin binding site 3HCDH_N PF02737.18 ETS76261.1 - 0.19 11.6 0.0 0.47 10.3 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 ETS76261.1 - 0.23 10.9 0.1 0.63 9.5 0.0 1.7 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus ABC_membrane PF00664.23 ETS76262.1 - 1.6e-54 185.4 24.8 3.4e-33 115.5 7.8 3.9 4 0 0 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.27 ETS76262.1 - 2.4e-51 173.8 0.0 3e-30 105.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_23 PF13476.6 ETS76262.1 - 3.8e-08 34.1 0.2 0.00037 21.0 0.0 3.1 3 0 0 3 3 2 2 AAA domain SMC_N PF02463.19 ETS76262.1 - 1.2e-07 31.4 0.3 0.14 11.5 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETS76262.1 - 2.3e-06 27.7 0.1 0.017 14.9 0.0 3.6 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 ETS76262.1 - 2.5e-05 24.3 1.1 0.03 14.4 0.0 3.5 4 0 0 4 4 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETS76262.1 - 2.7e-05 24.1 0.2 0.15 11.9 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_16 PF13191.6 ETS76262.1 - 4.9e-05 23.8 0.1 0.46 10.9 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 ETS76262.1 - 0.00025 20.7 0.3 0.73 9.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ETS76262.1 - 0.00043 20.6 0.1 3.1 8.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 ETS76262.1 - 0.00068 18.8 0.1 0.075 12.1 0.3 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.17 ETS76262.1 - 0.00095 19.3 2.0 0.014 15.5 0.0 2.7 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_15 PF13175.6 ETS76262.1 - 0.0051 16.6 0.0 1.9 8.1 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 ETS76262.1 - 0.0053 16.4 0.1 0.46 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ETS76262.1 - 0.0058 15.9 0.2 2.7 7.2 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.17 ETS76262.1 - 0.0099 15.6 0.0 2 8.1 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein CbiA PF01656.23 ETS76262.1 - 0.011 15.8 0.8 0.098 12.7 0.0 2.6 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 ETS76262.1 - 0.014 15.9 0.1 12 6.4 0.0 3.8 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 ETS76262.1 - 0.028 14.9 0.1 17 6.0 0.0 3.1 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 ETS76262.1 - 0.029 14.2 0.0 5.5 6.7 0.0 3.3 3 0 0 3 3 3 0 DEAD/DEAH box helicase Dynamin_N PF00350.23 ETS76262.1 - 0.045 13.8 0.5 4.7 7.2 0.0 2.8 2 0 0 2 2 2 0 Dynamin family cobW PF02492.19 ETS76262.1 - 0.048 13.2 1.8 0.75 9.4 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 ETS76262.1 - 0.059 13.5 0.0 4.1 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 ETS76262.1 - 0.062 12.2 1.4 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 ETS76262.1 - 0.071 12.8 1.6 12 5.5 0.1 3.4 4 0 0 4 4 2 0 AAA domain ATPase_2 PF01637.18 ETS76262.1 - 0.071 13.0 0.2 4.5 7.1 0.0 3.3 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea CLP1_P PF16575.5 ETS76262.1 - 0.091 12.6 0.2 1.9 8.3 0.0 2.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_7 PF12775.7 ETS76262.1 - 0.092 12.2 0.1 15 5.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ResIII PF04851.15 ETS76262.1 - 0.093 12.7 0.1 18 5.3 0.1 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF1180 PF06679.12 ETS76262.1 - 0.1 13.0 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) RNA_helicase PF00910.22 ETS76262.1 - 0.12 12.8 0.0 25 5.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 ETS76262.1 - 0.15 11.4 0.1 2.4 7.4 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2075 PF09848.9 ETS76262.1 - 0.15 11.3 0.4 16 4.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Adeno_IVa2 PF02456.15 ETS76262.1 - 0.16 10.7 0.0 1.1 7.9 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_24 PF13479.6 ETS76262.1 - 0.18 11.5 3.8 4.2 7.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 ETS76262.1 - 0.2 11.1 2.7 19 4.6 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein NACHT PF05729.12 ETS76262.1 - 0.32 10.9 2.5 6.5 6.6 0.2 2.6 2 0 0 2 2 2 0 NACHT domain RTA1 PF04479.13 ETS76263.1 - 5.2e-64 215.7 10.4 7.6e-64 215.1 10.4 1.2 1 0 0 1 1 1 1 RTA1 like protein DctQ PF04290.12 ETS76263.1 - 0.021 14.8 0.8 0.021 14.8 0.8 2.3 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Dioxygenase_C PF00775.21 ETS76264.1 - 1.7e-08 34.1 0.0 8.1e-07 28.6 0.0 2.2 2 0 0 2 2 2 2 Dioxygenase SIR2 PF02146.17 ETS76265.1 - 8.7e-40 136.5 0.0 1.8e-39 135.5 0.0 1.5 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 ETS76265.1 - 0.12 12.1 0.0 2 8.1 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain TPR_12 PF13424.6 ETS76266.1 - 1.3e-71 236.8 28.5 2.9e-17 62.7 1.5 6.0 3 1 3 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 ETS76266.1 - 2e-65 215.1 2.6 2e-10 40.2 0.0 8.6 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 ETS76266.1 - 1.3e-36 122.9 35.2 1.6e-05 24.5 1.6 8.8 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.6 ETS76266.1 - 5.1e-32 107.5 15.6 0.00031 20.6 0.1 8.8 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 ETS76266.1 - 8.7e-27 91.1 26.7 0.0013 18.7 0.2 8.7 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 ETS76266.1 - 6.2e-26 88.4 31.0 0.0018 18.3 0.1 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS76266.1 - 9.7e-21 74.5 6.6 5.3e-10 39.2 1.5 3.9 1 1 3 4 4 4 4 MalT-like TPR region HET PF06985.11 ETS76266.1 - 4.2e-13 49.9 4.9 7.6e-10 39.3 0.4 3.4 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) TPR_16 PF13432.6 ETS76266.1 - 6.6e-13 49.1 16.5 0.0057 17.3 0.2 8.1 7 2 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 ETS76266.1 - 9.2e-12 44.5 20.3 1.4 9.5 0.0 9.0 8 0 0 8 8 7 4 Tetratricopeptide repeat NB-ARC PF00931.22 ETS76266.1 - 5.8e-11 42.1 0.0 1.2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.6 ETS76266.1 - 9.3e-11 41.6 6.9 2.6 9.1 0.0 8.4 8 0 0 8 8 7 2 Tetratricopeptide repeat AAA_16 PF13191.6 ETS76266.1 - 4.6e-09 36.9 0.3 6e-08 33.3 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain PPR PF01535.20 ETS76266.1 - 2.6e-08 33.6 9.3 4 7.9 0.0 7.3 7 0 0 7 7 7 2 PPR repeat RPN7 PF10602.9 ETS76266.1 - 0.0013 18.5 9.3 13 5.4 0.0 6.1 3 1 2 6 6 6 0 26S proteasome subunit RPN7 RPN6_N PF18055.1 ETS76266.1 - 0.0017 18.7 8.4 9.9 6.6 0.2 5.3 4 1 0 5 5 5 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_21 PF09976.9 ETS76266.1 - 0.0069 16.1 18.6 9.2 5.9 1.0 6.2 2 1 3 5 5 5 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 ETS76266.1 - 0.0073 16.8 0.0 43 5.1 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 ETS76266.1 - 0.013 15.1 37.2 0.75 9.5 0.9 7.6 7 1 1 8 8 8 0 TPR repeat CutA1 PF03091.15 ETS76266.1 - 0.042 13.7 0.3 8.6 6.3 0.0 4.1 5 0 0 5 5 4 0 CutA1 divalent ion tolerance protein AAA_14 PF13173.6 ETS76266.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPR_3 PF07720.12 ETS76266.1 - 0.92 9.6 23.5 1.7 8.8 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 ETS76266.1 - 1.1 9.8 21.8 17 6.0 0.1 5.9 2 1 4 7 7 6 0 Tetratricopeptide repeat DUF4810 PF16068.5 ETS76266.1 - 1.4 9.5 15.8 13 6.4 0.2 6.7 7 0 0 7 7 7 0 Domain of unknown function (DUF4810) DUF2225 PF09986.9 ETS76266.1 - 2.6 7.7 12.6 10 5.8 1.5 3.8 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) RPN6_C_helix PF18503.1 ETS76266.1 - 4.3 7.1 10.6 10 5.9 0.1 4.8 5 0 0 5 5 5 0 26S proteasome subunit RPN6 C-terminal helix domain DLH PF01738.18 ETS76267.1 - 2.1e-12 47.0 0.0 2.6e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Fungal_trans PF04082.18 ETS76268.1 - 2.4e-11 43.2 0.1 4.8e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS76268.1 - 1.5e-08 34.6 17.7 2.8e-08 33.7 17.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Urb2 PF10441.9 ETS76268.1 - 0.11 12.4 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Urb2/Npa2 family DUF1345 PF07077.11 ETS76270.1 - 0.027 14.2 3.2 0.034 13.9 1.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1345) DUF5337 PF17272.2 ETS76270.1 - 0.58 10.0 3.5 0.37 10.7 0.4 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5337) Prion_bPrPp PF11587.8 ETS76270.1 - 1.9 8.4 6.1 31 4.5 0.1 2.7 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal PNTB PF02233.16 ETS76271.1 - 1.8e-174 581.0 24.4 1.8e-174 581.0 24.4 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 ETS76271.1 - 1.1e-74 250.3 0.9 3.2e-74 248.9 0.9 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 ETS76271.1 - 1.1e-48 165.0 0.2 3.3e-48 163.5 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 ETS76271.1 - 6.8e-31 106.6 3.5 6.8e-31 106.6 3.5 5.5 5 2 2 7 7 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch TPP_enzyme_M PF00205.22 ETS76271.1 - 0.00058 19.6 0.5 0.0071 16.1 0.3 2.8 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain 2-Hacid_dh_C PF02826.19 ETS76271.1 - 0.0037 16.6 0.1 0.23 10.8 0.1 2.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 ETS76271.1 - 0.018 14.3 0.1 0.04 13.1 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 ETS76271.1 - 0.021 14.8 2.1 0.051 13.5 0.3 2.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Fumerase PF05681.14 ETS76271.1 - 0.049 13.1 0.2 0.089 12.2 0.2 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) GIDA PF01134.22 ETS76271.1 - 0.093 11.8 1.1 0.16 11.0 1.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_2 PF03446.15 ETS76271.1 - 0.15 12.2 2.8 0.64 10.2 0.3 2.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_8 PF13450.6 ETS76271.1 - 5.9 7.2 8.5 0.73 10.1 2.0 3.1 3 1 0 3 3 2 0 NAD(P)-binding Rossmann-like domain Tyrosinase PF00264.20 ETS76272.1 - 1.7e-34 120.1 3.5 4.2e-34 118.8 3.5 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase Zn_clus PF00172.18 ETS76273.1 - 2.8e-06 27.3 13.2 2.8e-06 27.3 13.2 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ETS76274.1 - 1.5e-45 155.7 24.8 1.5e-45 155.7 24.8 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS76274.1 - 1e-14 54.2 0.1 1e-14 54.2 0.1 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter DUF3382 PF11862.8 ETS76274.1 - 0.091 13.0 2.2 0.28 11.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) SET PF00856.28 ETS76275.1 - 5.3e-16 59.5 0.0 6.2e-15 56.0 0.0 2.3 1 1 0 1 1 1 1 SET domain SAF PF08666.12 ETS76275.1 - 0.0066 17.0 0.2 6.2 7.5 0.0 2.4 2 0 0 2 2 2 2 SAF domain DUF4869 PF16163.5 ETS76276.1 - 0.012 15.3 0.1 0.016 14.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4869) Cellulase PF00150.18 ETS76277.1 - 2.4e-54 184.7 0.2 3.2e-54 184.2 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PLDc_2 PF13091.6 ETS76278.1 - 3.3e-17 62.6 0.0 4.7e-08 33.0 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 ETS76278.1 - 1.7e-08 34.3 1.5 0.0032 17.6 0.2 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif DnaG_DnaB_bind PF08278.11 ETS76278.1 - 0.08 13.5 0.0 0.42 11.2 0.0 2.0 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding VirArc_Nuclease PF12187.8 ETS76278.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral/Archaeal nuclease NDUFA12 PF05071.16 ETS76279.1 - 6e-31 107.1 2.2 7.8e-31 106.8 2.2 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Abhydrolase_6 PF12697.7 ETS76281.1 - 5e-17 63.2 0.1 6.1e-17 63.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 ETS76281.1 - 0.00014 21.5 0.0 0.0013 18.3 0.0 2.3 3 0 0 3 3 3 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 ETS76281.1 - 0.0032 17.2 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 ETS76281.1 - 0.0054 16.0 0.0 0.025 13.9 0.0 2.0 2 1 0 2 2 2 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 ETS76281.1 - 0.0097 15.5 0.0 0.078 12.5 0.0 2.0 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase DUF900 PF05990.12 ETS76281.1 - 0.011 15.3 0.0 0.032 13.7 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_8 PF06259.12 ETS76281.1 - 0.045 13.4 0.0 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase Abhydrolase_1 PF00561.20 ETS76281.1 - 0.14 11.8 0.1 0.6 9.7 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF218 PF02698.17 ETS76282.1 - 4.1e-21 75.4 0.0 5.9e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain AMP-binding PF00501.28 ETS76283.1 - 5.6e-76 255.8 0.0 7.1e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS76283.1 - 3.5e-13 50.3 0.3 1.7e-12 48.1 0.1 2.3 1 1 1 2 2 2 1 AMP-binding enzyme C-terminal domain DUF2624 PF11116.8 ETS76283.1 - 0.2 12.6 0.2 36 5.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Ank_2 PF12796.7 ETS76284.1 - 6.7e-06 26.6 0.1 2.1e-05 25.0 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS76284.1 - 2.6e-05 24.4 0.1 8.5e-05 22.8 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 ETS76284.1 - 0.00019 21.7 0.1 0.0014 19.0 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 ETS76284.1 - 0.00045 20.7 0.0 0.0014 19.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS76284.1 - 0.0018 18.6 0.0 0.012 16.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat OTT_1508_deam PF14441.6 ETS76284.1 - 0.0042 17.1 0.0 0.013 15.5 0.0 1.8 1 1 0 1 1 1 1 OTT_1508-like deaminase PK_C PF02887.16 ETS76284.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain CBP_BcsS PF17036.5 ETS76284.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsS MFS_1 PF07690.16 ETS76285.1 - 1.6e-34 119.4 28.0 1.6e-34 119.4 28.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily GlpM PF06942.12 ETS76285.1 - 3.2 8.2 10.4 0.07 13.6 1.4 2.8 3 0 0 3 3 3 0 GlpM protein p450 PF00067.22 ETS76286.1 - 2.7e-64 217.6 0.0 3.4e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ferric_reduct PF01794.19 ETS76287.1 - 6.7e-18 65.0 9.9 6.7e-18 65.0 9.9 2.0 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ETS76287.1 - 3.7e-07 30.4 0.0 8e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ETS76287.1 - 1.4e-06 28.3 0.0 3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Glyco_hydro_28 PF00295.17 ETS76288.1 - 4.5e-28 98.3 6.0 8.1e-28 97.4 6.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 ETS76288.1 - 7.5e-06 25.9 12.1 0.0023 17.8 11.8 3.6 1 1 0 1 1 1 1 Pectate lyase superfamily protein Baculo_PEP_C PF04513.12 ETS76289.1 - 0.0065 16.5 4.5 0.0065 16.5 4.5 5.3 3 2 2 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4551 PF15087.6 ETS76292.1 - 0.064 12.1 8.4 0.015 14.2 5.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) NACHT PF05729.12 ETS76293.1 - 3.1e-09 37.0 0.4 0.00045 20.2 0.1 2.8 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 ETS76293.1 - 2.1e-05 24.8 0.0 9.2e-05 22.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ETS76293.1 - 2.9e-05 24.6 1.8 0.0021 18.6 0.0 3.5 3 1 0 3 3 3 1 ABC transporter AAA_16 PF13191.6 ETS76293.1 - 9.3e-05 22.9 3.8 0.0002 21.8 0.0 3.3 4 1 0 4 4 3 1 AAA ATPase domain AAA_30 PF13604.6 ETS76293.1 - 0.00037 20.3 0.0 0.0012 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 ETS76293.1 - 0.0021 18.0 0.0 0.021 14.7 0.0 2.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea SesA PF17107.5 ETS76293.1 - 0.0033 17.6 0.8 0.012 15.8 0.3 2.4 2 0 0 2 2 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_18 PF13238.6 ETS76293.1 - 0.01 16.3 0.2 0.1 13.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.6 ETS76293.1 - 0.017 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 ETS76293.1 - 0.054 13.9 0.1 0.16 12.4 0.1 1.8 1 0 0 1 1 1 0 RNA helicase Helo_like_N PF17111.5 ETS76293.1 - 0.097 12.0 1.9 0.28 10.5 1.9 1.8 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins AAA_23 PF13476.6 ETS76293.1 - 0.12 12.9 1.6 0.68 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Nucleopor_Nup85 PF07575.13 ETS76293.1 - 0.82 8.2 7.8 0.054 12.1 1.3 2.1 3 0 0 3 3 3 0 Nup85 Nucleoporin FAD_oxidored PF12831.7 ETS76295.1 - 6.8e-85 286.0 0.0 9.9e-85 285.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fungal_trans PF04082.18 ETS76295.1 - 3.2e-27 95.2 0.2 4.9e-27 94.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Trp_halogenase PF04820.14 ETS76295.1 - 0.0097 14.8 0.9 0.26 10.1 0.1 2.2 1 1 1 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 ETS76295.1 - 0.011 15.0 0.4 0.025 13.8 0.1 1.7 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS76295.1 - 0.053 12.6 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF1338 PF07063.13 ETS76295.1 - 0.062 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) NAD_binding_8 PF13450.6 ETS76295.1 - 0.11 12.7 0.2 0.45 10.8 0.2 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS76295.1 - 0.65 9.0 2.5 2.3 7.2 0.5 2.5 2 1 0 3 3 3 0 FAD binding domain FAD_oxidored PF12831.7 ETS76296.1 - 7.3e-86 289.2 0.0 8.2e-86 289.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ETS76296.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Sugar_tr PF00083.24 ETS76297.1 - 4.2e-94 316.0 12.5 5.7e-94 315.5 12.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS76297.1 - 6.7e-21 74.6 25.0 7.4e-16 58.0 6.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 ETS76297.1 - 0.019 13.2 0.1 0.019 13.2 0.1 2.0 3 0 0 3 3 3 0 BT1 family EBP PF05241.12 ETS76297.1 - 0.051 13.0 5.7 0.053 13.0 3.0 2.3 3 0 0 3 3 3 0 Emopamil binding protein GCV_T_C PF08669.11 ETS76297.1 - 0.097 12.6 0.1 0.28 11.1 0.1 1.8 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain adh_short_C2 PF13561.6 ETS76299.1 - 1.9e-62 210.9 0.8 2.3e-62 210.6 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS76299.1 - 3.3e-44 150.7 0.7 4e-44 150.4 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS76299.1 - 3.4e-10 40.1 0.4 6.6e-10 39.2 0.4 1.4 1 1 0 1 1 1 1 KR domain ThiF PF00899.21 ETS76299.1 - 0.00023 20.6 6.0 0.19 11.0 0.1 2.3 2 0 0 2 2 2 2 ThiF family Polysacc_synt_2 PF02719.15 ETS76299.1 - 0.035 13.2 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein zf-C2H2 PF00096.26 ETS76300.1 - 1e-05 25.7 22.3 0.00012 22.4 5.7 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-UBR PF02207.20 ETS76300.1 - 0.00035 20.7 1.9 0.00062 19.9 1.9 1.3 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-C2H2_4 PF13894.6 ETS76300.1 - 0.0025 18.5 4.3 0.0025 18.5 4.3 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ETS76300.1 - 0.0092 16.3 2.1 0.0092 16.3 2.1 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 ETS76300.1 - 0.018 15.5 18.3 0.11 12.9 6.4 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2HC_2 PF13913.6 ETS76300.1 - 0.089 12.7 1.0 0.089 12.7 1.0 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type BIR PF00653.21 ETS76300.1 - 0.13 12.9 1.9 0.37 11.5 0.7 2.2 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain DUF2225 PF09986.9 ETS76300.1 - 0.16 11.7 1.7 0.29 10.8 1.6 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-RING_UBOX PF13445.6 ETS76300.1 - 0.17 11.9 2.5 0.31 11.1 2.5 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C2H2_2 PF12756.7 ETS76300.1 - 8.4 6.8 9.9 15 6.0 4.2 2.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) NmrA PF05368.13 ETS76301.1 - 9.7e-20 71.1 0.0 1.1e-19 70.9 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 ETS76301.1 - 5.7e-06 26.6 0.0 1.4e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ETS76301.1 - 0.013 15.5 0.2 0.052 13.6 0.1 2.2 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.16 ETS76301.1 - 0.074 13.7 0.1 0.2 12.3 0.0 1.8 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Forkhead PF00250.18 ETS76302.1 - 5.2e-31 106.8 0.4 9.4e-31 105.9 0.4 1.4 1 0 0 1 1 1 1 Forkhead domain MA3 PF02847.17 ETS76303.1 - 3.4e-23 81.8 0.7 7e-23 80.8 0.1 1.9 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 ETS76303.1 - 3.5e-13 49.7 0.3 6.7e-13 48.8 0.3 1.5 1 0 0 1 1 1 1 MIF4G domain Cnd1 PF12717.7 ETS76303.1 - 0.014 15.5 0.3 0.037 14.1 0.3 1.7 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Na_trans_assoc PF06512.13 ETS76303.1 - 0.24 11.7 3.1 0.47 10.7 3.1 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated DPM2 PF07297.12 ETS76304.1 - 1.5e-27 95.7 2.6 1.7e-27 95.5 2.6 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 ETS76304.1 - 0.0006 19.7 1.7 0.00065 19.6 1.7 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.6 ETS76304.1 - 0.0024 18.0 6.9 0.0088 16.1 6.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4229) COX14 PF14880.6 ETS76304.1 - 0.019 14.8 0.9 0.66 9.9 0.0 2.1 2 0 0 2 2 2 0 Cytochrome oxidase c assembly LapA_dom PF06305.11 ETS76304.1 - 0.023 14.5 0.3 0.023 14.5 0.3 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PP2C PF00481.21 ETS76306.1 - 1.5e-32 113.2 0.0 2.4e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PUF PF00806.19 ETS76308.1 - 6.1e-50 164.2 7.3 1.1e-08 34.2 0.2 8.3 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat DUF4687 PF15747.5 ETS76308.1 - 0.033 14.7 1.0 0.13 12.8 1.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4687) SKG6 PF08693.10 ETS76309.1 - 0.14 11.6 1.5 0.21 11.0 1.5 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Fungal_trans PF04082.18 ETS76310.1 - 8e-10 38.2 0.4 1.5e-09 37.3 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS76310.1 - 1.2e-08 34.9 10.4 2.3e-08 34.0 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3439 PF11921.8 ETS76310.1 - 3.3 7.7 11.7 12 5.9 11.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 ETS76310.1 - 6.3 4.9 13.5 9.1 4.3 13.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Phosphodiest PF01663.22 ETS76311.1 - 6.1e-13 49.1 0.5 6.1e-13 49.1 0.5 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ETS76311.1 - 0.00013 21.5 0.1 0.00023 20.7 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 ETS76311.1 - 0.00064 19.2 0.7 0.0012 18.2 0.7 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 ETS76311.1 - 0.51 10.4 1.7 9.3 6.3 0.4 2.5 2 0 0 2 2 2 0 PglZ domain NYAP_C PF15452.6 ETS76312.1 - 0.0087 15.9 0.5 0.014 15.3 0.5 1.3 1 0 0 1 1 1 1 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter DLIC PF05783.11 ETS76312.1 - 0.18 10.6 4.0 0.42 9.4 3.9 1.6 1 1 0 1 1 1 0 Dynein light intermediate chain (DLIC) Sporozoite_P67 PF05642.11 ETS76312.1 - 0.54 8.3 8.2 0.82 7.7 8.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ABC_membrane PF00664.23 ETS76313.1 - 3.6e-106 354.8 41.4 1.4e-53 182.3 19.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ETS76313.1 - 1.4e-66 223.2 0.0 1.7e-32 112.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ETS76313.1 - 3.1e-12 46.4 0.0 0.00016 21.1 0.0 3.5 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ETS76313.1 - 1.1e-06 28.3 5.0 0.0031 17.2 0.2 4.0 4 0 0 4 4 4 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ETS76313.1 - 7e-06 26.0 0.0 0.17 11.7 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase ABC_ATPase PF09818.9 ETS76313.1 - 8.4e-06 24.8 4.1 0.047 12.5 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 ETS76313.1 - 3.6e-05 24.2 7.3 0.012 16.0 0.0 3.7 3 1 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.6 ETS76313.1 - 0.00025 20.7 0.2 0.44 10.1 0.2 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 ETS76313.1 - 0.00042 20.6 1.7 0.55 10.5 0.0 3.6 3 1 0 3 3 2 1 AAA domain AAA_15 PF13175.6 ETS76313.1 - 0.00056 19.7 0.7 0.46 10.1 0.0 2.5 3 0 0 3 3 2 2 AAA ATPase domain AAA PF00004.29 ETS76313.1 - 0.0009 19.7 2.1 5.5 7.4 0.1 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 ETS76313.1 - 0.0034 17.6 1.9 4.4 7.6 0.2 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 ETS76313.1 - 0.0054 17.0 0.7 0.52 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 ETS76313.1 - 0.0071 15.5 0.0 3.5 6.7 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_21 PF13304.6 ETS76313.1 - 0.0073 16.2 3.1 4.4 7.0 0.0 3.7 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 ETS76313.1 - 0.0088 15.8 5.6 1.4 8.6 0.1 3.5 3 1 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 ETS76313.1 - 0.0091 15.3 0.1 4.3 6.6 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.14 ETS76313.1 - 0.016 15.2 0.3 13 5.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 ETS76313.1 - 0.023 14.8 3.3 7.3 6.6 0.1 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_23 PF13476.6 ETS76313.1 - 0.025 15.1 1.0 2.4 8.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 ETS76313.1 - 0.026 15.0 0.7 11 6.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 ETS76313.1 - 0.027 14.0 0.0 4.7 6.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region PapJ PF14855.6 ETS76313.1 - 0.028 14.1 0.3 0.71 9.5 0.0 2.4 2 0 0 2 2 2 0 Pilus-assembly fibrillin subunit, chaperone AAA_33 PF13671.6 ETS76313.1 - 0.046 13.9 1.1 14 5.8 0.1 3.0 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.22 ETS76313.1 - 0.047 13.3 0.1 4.7 6.8 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PRK PF00485.18 ETS76313.1 - 0.061 13.0 0.1 2.2 7.9 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF815 PF05673.13 ETS76313.1 - 0.067 12.3 0.1 4.2 6.4 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF815) Rad17 PF03215.15 ETS76313.1 - 0.075 13.0 0.0 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 ETS76313.1 - 0.097 13.1 0.7 18 5.8 0.0 3.7 3 0 0 3 3 3 0 RNA helicase AAA_24 PF13479.6 ETS76313.1 - 0.12 12.1 0.1 7.5 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 ETS76313.1 - 0.15 12.0 0.1 3 7.7 0.1 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 ETS76313.1 - 3.7 7.7 4.8 19 5.3 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase LMBR1 PF04791.16 ETS76314.1 - 8e-119 397.8 1.6 9.1e-119 397.7 1.6 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein UPF0113_N PF17833.1 ETS76315.1 - 7.6e-25 87.3 0.0 1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 ETS76315.1 - 4.8e-24 84.4 0.0 7.4e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 ETS76315.1 - 0.043 13.8 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 PUA domain NOC3p PF07540.11 ETS76316.1 - 2.1e-27 95.4 2.8 2.4e-27 95.2 0.2 2.6 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.17 ETS76316.1 - 1.1e-25 90.7 0.5 4.5e-25 88.6 0.0 2.3 2 0 0 2 2 2 1 CBF/Mak21 family RskA PF10099.9 ETS76316.1 - 0.12 12.7 1.0 1.8 8.8 0.0 2.9 2 1 0 2 2 2 0 Anti-sigma-K factor rskA DUF3860 PF12976.7 ETS76317.1 - 0.016 15.2 0.0 0.048 13.7 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) RNase_P_pop3 PF08228.11 ETS76318.1 - 1.5e-11 44.6 0.0 2.1e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF3517 PF12030.8 ETS76319.1 - 5.1e-71 239.3 0.5 2.6e-70 237.0 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3517) UCH PF00443.29 ETS76319.1 - 2.9e-40 138.4 0.2 2.9e-39 135.1 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ETS76319.1 - 6e-20 72.1 0.5 1.8e-19 70.5 0.5 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Spt20 PF12090.8 ETS76320.1 - 0.06 13.0 11.1 0.11 12.1 11.1 1.4 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 ETS76320.1 - 0.078 13.0 11.5 0.0088 16.1 7.0 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 ETS76320.1 - 0.12 11.0 15.9 0.13 10.9 1.4 2.2 2 0 0 2 2 2 0 Hamartin protein Pex14_N PF04695.13 ETS76320.1 - 0.38 11.4 7.0 0.21 12.3 0.8 2.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4175 PF13779.6 ETS76320.1 - 1 7.2 12.3 1.6 6.6 12.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DivIC PF04977.15 ETS76320.1 - 8.1 6.3 10.5 2 8.3 6.8 1.9 2 0 0 2 2 2 0 Septum formation initiator Helo_like_N PF17111.5 ETS76323.1 - 1.1e-08 34.7 2.2 1.4e-08 34.3 2.2 1.1 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Adeno_E1B_19K PF01691.16 ETS76323.1 - 0.1 12.2 0.6 0.38 10.3 0.1 2.0 2 0 0 2 2 2 0 Adenovirus E1B 19K protein / small t-antigen NACHT PF05729.12 ETS76324.1 - 0.00024 21.0 0.0 0.0013 18.7 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ETS76324.1 - 0.00037 20.8 0.0 0.0009 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS76324.1 - 0.0012 19.2 0.0 0.005 17.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain PD40 PF07676.12 ETS76324.1 - 0.02 14.8 0.7 5.7 7.0 0.1 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat VHL_C PF17211.3 ETS76324.1 - 0.029 14.4 0.1 0.09 12.8 0.1 1.8 1 0 0 1 1 1 0 VHL box domain RNA_helicase PF00910.22 ETS76324.1 - 0.061 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 ETS76324.1 - 0.16 12.4 0.0 0.49 10.8 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Dynamin_M PF01031.20 ETS76324.1 - 0.22 10.7 0.1 0.39 9.9 0.1 1.3 1 0 0 1 1 1 0 Dynamin central region Cytidylate_kin PF02224.18 ETS76324.1 - 0.23 11.2 0.0 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase Helo_like_N PF17111.5 ETS76325.1 - 1.4e-36 125.8 3.7 1.7e-36 125.6 3.7 1.1 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins KxDL PF10241.9 ETS76325.1 - 0.001 19.3 0.8 3.2 8.1 0.0 3.1 2 1 1 3 3 3 2 Uncharacterized conserved protein DUF3829 PF12889.7 ETS76325.1 - 0.03 13.8 0.2 1.4 8.3 0.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3829) DHC_N1 PF08385.12 ETS76325.1 - 0.062 11.9 0.4 1.3 7.5 0.0 2.1 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 PAC2 PF09754.9 ETS76325.1 - 0.11 12.5 0.1 0.68 9.9 0.0 2.0 2 0 0 2 2 2 0 PAC2 family Alpha_adaptinC2 PF02883.20 ETS76325.1 - 0.13 12.6 0.8 0.5 10.7 0.8 1.9 1 1 0 1 1 1 0 Adaptin C-terminal domain DUF3176 PF11374.8 ETS76326.1 - 6.7e-27 93.8 2.0 1.8e-26 92.4 2.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) TPP_enzyme_N PF02776.18 ETS76326.1 - 7.8e-08 32.1 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain HET PF06985.11 ETS76327.1 - 8.2e-24 84.6 0.0 1.8e-23 83.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tyrosinase PF00264.20 ETS76328.1 - 1.5e-28 100.6 2.4 2.1e-28 100.1 2.4 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase FAD_binding_3 PF01494.19 ETS76329.1 - 2.3e-10 40.2 0.6 4.9e-05 22.7 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 ETS76329.1 - 1.3e-08 34.8 0.2 0.0017 18.0 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS76329.1 - 1.5e-07 30.5 0.0 2.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 ETS76329.1 - 5.1e-05 22.7 0.1 0.011 15.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS76329.1 - 0.0001 22.4 0.0 0.00045 20.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS76329.1 - 0.00055 19.1 0.0 0.00084 18.5 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ETS76329.1 - 0.011 15.0 0.1 0.024 13.9 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ETS76329.1 - 0.019 14.3 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS76329.1 - 0.049 14.2 0.0 0.18 12.4 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_4 PF01565.23 ETS76330.1 - 1.2e-21 77.0 0.9 2.4e-21 75.9 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain Clr5 PF14420.6 ETS76332.1 - 3.4e-15 56.0 6.1 5.7e-15 55.3 4.3 2.2 2 0 0 2 2 2 1 Clr5 domain Ank_2 PF12796.7 ETS76333.1 - 4.4e-21 75.3 2.1 5.9e-13 49.2 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS76333.1 - 1.2e-17 64.0 0.0 6.6e-06 26.6 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 ETS76333.1 - 1.5e-12 47.3 1.4 8.1e-12 44.9 1.4 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_5 PF13857.6 ETS76333.1 - 3e-12 46.5 0.2 0.00034 20.8 0.0 4.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 ETS76333.1 - 1.1e-11 44.7 2.3 0.0084 16.5 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 ETS76333.1 - 3e-09 36.4 0.1 0.00082 19.7 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat NACHT PF05729.12 ETS76333.1 - 4e-05 23.6 0.0 0.00011 22.1 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ETS76333.1 - 0.00015 22.1 0.1 0.0044 17.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AFG1_ATPase PF03969.16 ETS76333.1 - 0.02 13.8 0.0 0.038 12.9 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase ATP-synt_ab PF00006.25 ETS76333.1 - 0.038 13.6 0.0 2.2 7.9 0.0 2.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF937 PF06078.11 ETS76333.1 - 0.2 12.3 3.5 0.76 10.4 3.3 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) VWA_3_C PF18571.1 ETS76333.1 - 3.1 7.8 5.3 24 4.9 0.1 3.4 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain GST_N_3 PF13417.6 ETS76336.1 - 6.8e-05 23.2 0.1 0.00056 20.3 0.1 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS76336.1 - 0.0012 18.8 0.1 0.0023 17.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ETS76336.1 - 0.077 13.3 0.0 0.33 11.3 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ETS76336.1 - 0.088 13.2 0.0 0.19 12.1 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain MFS_1 PF07690.16 ETS76337.1 - 2e-33 115.8 41.7 2e-33 115.8 41.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS76337.1 - 4e-12 45.7 10.9 4e-12 45.7 10.9 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter NADH-u_ox-rdase PF10785.9 ETS76337.1 - 0.024 15.3 1.7 0.37 11.5 0.0 3.4 4 1 0 4 4 4 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit UPF0139 PF03669.13 ETS76337.1 - 3.1 7.7 7.4 3 7.8 0.3 3.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0139) p450 PF00067.22 ETS76338.1 - 4.3e-70 236.7 0.0 5.5e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS76339.1 - 9.9e-50 169.6 0.0 1.3e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TetR_C_8 PF14278.6 ETS76339.1 - 0.15 12.2 0.0 0.69 10.0 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region Coa1 PF08695.10 ETS76339.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 FA_desaturase PF00487.24 ETS76340.1 - 3.7e-12 46.6 27.1 3.7e-12 46.6 27.1 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Clr5 PF14420.6 ETS76341.1 - 6e-15 55.2 1.2 1.2e-14 54.2 1.2 1.5 1 0 0 1 1 1 1 Clr5 domain Ank_2 PF12796.7 ETS76342.1 - 1.5e-26 92.8 11.7 1.1e-09 38.7 0.1 5.2 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS76342.1 - 5.4e-22 75.5 5.2 0.0038 17.6 0.0 8.8 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 ETS76342.1 - 1.3e-20 73.4 5.5 4.2e-05 24.0 0.1 7.5 4 3 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS76342.1 - 5.7e-17 61.6 2.4 0.035 14.5 0.0 6.6 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 ETS76342.1 - 1.2e-09 38.2 5.1 2 9.0 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat Helo_like_N PF17111.5 ETS76342.1 - 9.5e-05 21.9 1.8 0.00012 21.5 0.1 2.0 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins PLAC9 PF15205.6 ETS76342.1 - 0.048 14.1 0.1 0.91 10.0 0.0 2.7 2 0 0 2 2 2 0 Placenta-specific protein 9 Tup_N PF08581.10 ETS76342.1 - 0.11 12.8 0.2 0.45 10.8 0.2 2.0 1 0 0 1 1 1 0 Tup N-terminal Cep57_MT_bd PF06657.13 ETS76342.1 - 0.18 12.3 1.3 0.49 10.9 0.1 2.4 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 LIM PF00412.22 ETS76344.1 - 3.9e-08 33.4 13.2 1.5e-07 31.5 6.1 2.6 1 1 1 2 2 2 2 LIM domain Helo_like_N PF17111.5 ETS76344.1 - 7.1e-06 25.5 3.4 1.2e-05 24.8 3.4 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins REC104 PF17378.2 ETS76344.1 - 0.029 14.2 0.6 0.052 13.4 0.6 1.4 1 0 0 1 1 1 0 Meiotic recombination protein REC104 DUF4317 PF14199.6 ETS76344.1 - 0.04 13.1 1.2 0.061 12.5 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) bZIP_1 PF00170.21 ETS76344.1 - 0.079 13.1 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 bZIP transcription factor SesA PF17107.5 ETS76344.1 - 0.15 12.3 1.5 0.58 10.4 0.0 2.3 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases zf-FLZ PF04570.14 ETS76344.1 - 4.2 6.9 16.5 12 5.4 8.4 3.5 2 1 1 3 3 3 0 zinc-finger of the FCS-type, C2-C2 PRCC PF10253.9 ETS76345.1 - 2.4e-34 120.0 8.7 2.4e-34 120.0 8.7 2.8 1 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting CRIM PF16978.5 ETS76346.1 - 2.4e-44 150.9 0.0 5.1e-44 149.8 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 ETS76346.1 - 8.6e-26 90.4 0.0 2.3e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 ETS76346.1 - 0.032 14.4 0.1 0.078 13.2 0.1 1.6 1 0 0 1 1 1 0 TUG ubiquitin-like domain Cu_bind_like PF02298.17 ETS76349.1 - 0.011 15.7 0.1 0.03 14.3 0.1 1.7 1 1 0 1 1 1 0 Plastocyanin-like domain Cas_csx3 PF09620.10 ETS76349.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) VP4_2 PF08935.10 ETS76349.1 - 0.099 13.2 1.2 0.25 11.9 1.2 1.7 1 0 0 1 1 1 0 Viral protein VP4 subunit Egh16-like PF11327.8 ETS76350.1 - 1.8e-26 93.7 7.5 1.8e-26 93.7 7.5 2.1 2 2 0 2 2 2 1 Egh16-like virulence factor Amidohydro_2 PF04909.14 ETS76351.1 - 2.9e-27 96.2 0.1 5.2e-27 95.4 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 ETS76351.1 - 0.14 11.5 0.0 0.42 10.0 0.0 1.7 2 0 0 2 2 2 0 TatD related DNase DUF3176 PF11374.8 ETS76352.1 - 1.6e-29 102.3 1.0 2.6e-29 101.6 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Pam17 PF08566.10 ETS76352.1 - 0.0073 16.2 0.1 0.019 14.8 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial import protein Pam17 DUF3433 PF11915.8 ETS76352.1 - 0.045 14.2 4.4 0.1 13.1 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3433) Helo_like_N PF17111.5 ETS76353.1 - 2.1e-17 63.2 6.0 5.1e-17 61.9 5.7 1.7 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 ETS76353.1 - 0.042 14.0 0.8 0.042 14.0 0.8 2.4 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases WD40 PF00400.32 ETS76354.1 - 5.3e-21 74.5 14.0 5.4e-05 23.9 0.0 11.3 12 0 0 12 12 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS76354.1 - 1e-18 67.4 0.0 0.003 17.8 0.0 7.9 3 2 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 ETS76354.1 - 5.4e-11 42.5 0.3 0.071 12.7 0.1 4.4 3 1 1 4 4 4 3 PQQ-like domain NACHT PF05729.12 ETS76354.1 - 4.9e-07 29.8 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS76354.1 - 9.8e-05 22.8 0.1 0.00035 21.0 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Nup160 PF11715.8 ETS76354.1 - 0.00014 20.7 2.2 0.022 13.4 0.1 3.3 3 0 0 3 3 3 1 Nucleoporin Nup120/160 PD40 PF07676.12 ETS76354.1 - 0.00016 21.5 9.8 0.98 9.4 0.4 7.7 10 0 0 10 10 9 1 WD40-like Beta Propeller Repeat PQQ PF01011.21 ETS76354.1 - 0.00023 20.9 0.0 16 5.7 0.0 6.2 8 0 0 8 8 8 0 PQQ enzyme repeat WD40_like PF17005.5 ETS76354.1 - 0.00038 19.9 0.0 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 ETS76354.1 - 0.0054 16.6 0.1 19 5.1 0.0 4.2 4 1 1 5 5 5 0 Eukaryotic translation initiation factor eIF2A ATPase_2 PF01637.18 ETS76354.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 ETS76354.1 - 0.03 13.5 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Ge1_WD40 PF16529.5 ETS76354.1 - 0.056 12.4 0.0 18 4.2 0.0 3.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DPPIV_N PF00930.21 ETS76354.1 - 0.12 11.1 0.9 9.4 4.9 0.0 3.7 4 1 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Gmad1 PF10647.9 ETS76354.1 - 0.19 11.4 1.8 2.4 7.8 0.1 2.7 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain AAA_30 PF13604.6 ETS76354.1 - 0.2 11.3 0.0 0.42 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 ETS76355.1 - 2.6e-44 151.8 0.0 3.8e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DIOX_N PF14226.6 ETS76356.1 - 2.1e-24 86.5 0.0 3.6e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS76356.1 - 2.3e-18 66.5 0.0 3.7e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CheW PF01584.19 ETS76356.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 CheW-like domain Abhydrolase_6 PF12697.7 ETS76357.1 - 0.00078 20.1 5.0 0.0035 18.0 5.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 ETS76357.1 - 0.0024 17.4 0.0 0.0042 16.6 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 ETS76357.1 - 0.0046 16.7 0.0 0.0076 16.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 ETS76357.1 - 0.032 14.3 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.8 ETS76357.1 - 0.057 12.7 0.6 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 ETS76357.1 - 0.14 12.0 0.2 0.34 10.7 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PTPLA PF04387.14 ETS76358.1 - 2.4e-47 160.7 6.0 3.2e-47 160.3 6.0 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA HET PF06985.11 ETS76359.1 - 5e-31 108.0 0.2 1.6e-28 99.9 0.2 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ebola_NP PF05505.12 ETS76360.1 - 0.09 11.1 0.0 0.12 10.6 0.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein HEAT PF02985.22 ETS76362.1 - 0.00015 21.7 0.0 0.027 14.7 0.0 3.0 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 ETS76362.1 - 0.0017 18.7 0.0 0.25 11.8 0.0 2.7 2 0 0 2 2 2 1 HEAT repeats zf-Sec23_Sec24 PF04810.15 ETS76362.1 - 0.038 14.0 1.2 22 5.2 0.1 3.4 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Cohesin_HEAT PF12765.7 ETS76362.1 - 0.042 14.2 1.6 0.06 13.7 0.5 1.8 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 ETS76362.1 - 0.059 13.4 0.0 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Attractin PF08037.11 ETS76362.1 - 0.11 12.5 1.7 0.3 11.1 1.7 1.8 1 0 0 1 1 1 0 Attractin family zf-C2H2_2 PF12756.7 ETS76362.1 - 0.14 12.5 3.6 0.23 11.8 0.4 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 ETS76362.1 - 0.15 12.4 12.5 11 6.4 0.1 3.6 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Toxin_ToxA PF11584.8 ETS76362.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA Peptidase_S8 PF00082.22 ETS76363.1 - 5.1e-16 58.8 0.0 8.4e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Glyco_hydro_88 PF07470.13 ETS76365.1 - 3.9e-66 223.5 12.7 4.7e-66 223.2 12.7 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Cna_B PF05738.13 ETS76365.1 - 0.021 15.4 2.0 0.049 14.2 2.0 1.7 1 0 0 1 1 1 0 Cna protein B-type domain DUF3328 PF11807.8 ETS76366.1 - 7.2e-25 88.0 0.0 1e-24 87.6 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Bac_luciferase PF00296.20 ETS76367.1 - 4.9e-69 233.2 0.0 5.8e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 ETS76368.1 - 4e-45 154.3 44.6 4e-45 154.3 44.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS76368.1 - 3.6e-14 52.5 25.6 1.2e-12 47.5 13.6 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter Pox_A14 PF05767.12 ETS76368.1 - 0.44 10.7 2.8 0.37 11.0 0.4 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 AMP-binding PF00501.28 ETS76369.1 - 4.3e-76 256.2 0.0 6.5e-76 255.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ETS76369.1 - 8.3e-68 228.3 0.0 1.2e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 ETS76369.1 - 1.7e-09 37.9 0.0 4e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 ETS76369.1 - 1.7e-09 37.5 0.0 3.5e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS76369.1 - 4.4e-08 32.5 0.0 1.1e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 ETS76369.1 - 1.3e-05 26.1 0.0 9.5e-05 23.3 0.0 2.5 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 ETS76369.1 - 0.0093 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ETS76369.1 - 0.021 14.0 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ETS76369.1 - 0.1 11.7 0.1 0.42 9.7 0.1 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain Arylsulfotran_2 PF14269.6 ETS76370.1 - 1.6e-75 254.3 0.9 2e-75 254.0 0.5 1.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 ETS76370.1 - 1.8e-14 53.4 0.1 3.9e-13 49.1 0.1 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) MIP PF00230.20 ETS76371.1 - 1.1e-50 172.5 15.1 1.4e-50 172.1 15.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein LVIVD PF08309.11 ETS76372.1 - 0.12 11.7 0.6 7.2 6.0 0.0 3.5 4 0 0 4 4 4 0 LVIVD repeat FAD_binding_4 PF01565.23 ETS76373.1 - 1.7e-17 63.5 0.0 2.8e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DGF-1_C PF11040.8 ETS76374.1 - 0.6 10.2 0.0 0.6 10.2 0.0 3.1 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus CorA PF01544.18 ETS76375.1 - 2.2e-25 89.6 4.7 2e-21 76.6 3.0 2.5 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Aquarius_N PF16399.5 ETS76376.1 - 0 1054.2 0.1 0 1053.8 0.1 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 ETS76376.1 - 3.8e-26 92.0 0.0 6.5e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ETS76376.1 - 6.9e-21 75.2 0.0 1.8e-20 73.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ETS76376.1 - 4.3e-07 29.8 0.0 0.00073 19.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 ETS76376.1 - 3.1e-06 27.3 0.0 9.7e-06 25.7 0.0 1.8 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ETS76376.1 - 6.7e-06 26.5 0.2 9.1e-05 22.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS76376.1 - 0.00091 19.7 0.0 0.0041 17.5 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 ETS76376.1 - 0.0022 17.4 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.29 ETS76376.1 - 0.0026 18.2 0.0 0.016 15.6 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 ETS76376.1 - 0.0065 16.2 0.2 0.5 10.1 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase SMC_N PF02463.19 ETS76376.1 - 0.011 15.2 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 ETS76376.1 - 0.023 14.7 0.1 0.57 10.2 0.0 3.3 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.6 ETS76376.1 - 0.028 14.2 2.6 0.1 12.5 0.1 2.7 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 ETS76376.1 - 0.04 14.2 0.3 0.32 11.3 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.6 ETS76376.1 - 0.06 12.9 0.0 0.6 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 ETS76376.1 - 0.087 12.0 0.6 0.23 10.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Adeno_IVa2 PF02456.15 ETS76376.1 - 0.17 10.7 0.0 0.35 9.6 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein efThoc1 PF11957.8 ETS76377.1 - 3.3e-117 392.1 0.8 3.3e-117 392.1 0.8 2.2 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 ETS76377.1 - 8.8e-34 116.8 0.2 8.8e-34 116.8 0.2 2.0 2 0 0 2 2 1 1 Guanylate kinase MMR_HSR1 PF01926.23 ETS76377.1 - 6.9e-07 29.4 0.0 1.7e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETS76377.1 - 5.4e-06 26.4 0.0 9e-05 22.4 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 ETS76377.1 - 0.00027 21.2 0.0 0.00093 19.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain SR-25 PF10500.9 ETS76377.1 - 0.00051 19.7 14.0 0.0012 18.6 14.0 1.7 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AAA_28 PF13521.6 ETS76377.1 - 0.0009 19.5 0.1 0.0031 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS76377.1 - 0.0022 18.4 0.0 0.0075 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ETS76377.1 - 0.0028 18.2 0.0 0.0028 18.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.27 ETS76377.1 - 0.12 12.9 1.6 0.57 10.7 1.6 2.3 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 ETS76377.1 - 0.16 12.2 0.0 0.16 12.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain TSGP1 PF07771.11 ETS76377.1 - 1.2 9.3 15.7 9.8 6.4 15.7 2.6 1 1 0 1 1 1 0 Tick salivary peptide group 1 EOS1 PF12326.8 ETS76377.1 - 7.6 6.4 7.1 21 5.0 7.1 1.8 1 0 0 1 1 1 0 N-glycosylation protein MIF4G PF02854.19 ETS76378.1 - 2.1e-50 171.3 0.0 3.5e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 ETS76378.1 - 1.8e-21 76.1 0.4 5.1e-21 74.6 0.4 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 DUF4148 PF13663.6 ETS76378.1 - 0.073 13.3 3.6 1.3 9.3 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Borrelia_P83 PF05262.11 ETS76378.1 - 6.3 5.2 51.3 0.12 10.9 40.8 2.8 3 0 0 3 3 3 0 Borrelia P83/100 protein DNA_pol_B PF00136.21 ETS76379.1 - 1.1e-116 390.3 0.8 2e-116 389.4 0.8 1.4 1 1 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 ETS76379.1 - 7.6e-69 231.2 0.3 1.4e-68 230.3 0.3 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 ETS76379.1 - 3.4e-41 141.5 0.0 6.7e-41 140.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 ETS76379.1 - 1.6e-24 85.8 9.2 1.6e-24 85.8 9.2 3.2 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 ETS76379.1 - 0.00048 19.1 0.5 0.027 13.3 0.0 2.7 3 0 0 3 3 3 1 DNA polymerase type B, organellar and viral RTP1_C1 PF10363.9 ETS76380.1 - 0.0017 18.5 0.1 0.021 15.0 0.0 2.8 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 ETS76380.1 - 0.0026 17.8 3.5 0.054 13.8 0.2 4.5 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 ETS76380.1 - 0.014 15.8 2.6 1.4 9.4 0.0 4.3 4 0 0 4 4 4 0 HEAT repeats DUF1749 PF08538.10 ETS76381.1 - 5.3e-76 255.6 0.0 6.5e-76 255.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 ETS76381.1 - 2e-06 28.6 0.0 2.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS76381.1 - 0.0001 21.7 0.0 0.014 14.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS76381.1 - 0.0003 20.5 0.1 0.031 13.9 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold DUF3530 PF12048.8 ETS76381.1 - 0.02 14.3 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Ser_hydrolase PF06821.13 ETS76381.1 - 0.026 14.4 0.0 0.066 13.1 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase LCAT PF02450.15 ETS76381.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase p450 PF00067.22 ETS76382.1 - 9.5e-46 156.5 0.3 1.6e-44 152.4 0.3 2.0 1 1 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.23 ETS76383.1 - 1e-84 284.4 31.5 8e-45 153.6 6.1 2.6 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ETS76383.1 - 7e-51 172.3 0.1 6.4e-29 101.2 0.1 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ETS76383.1 - 7.4e-11 41.9 3.3 0.0095 15.4 0.4 4.3 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ETS76383.1 - 5.3e-06 26.9 0.6 0.044 14.2 0.4 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 ETS76383.1 - 8.5e-06 25.8 0.6 0.099 12.7 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETS76383.1 - 1.7e-05 24.8 0.1 0.14 12.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ETS76383.1 - 7.6e-05 22.4 0.1 0.077 12.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 ETS76383.1 - 0.00048 20.0 1.1 0.14 12.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ETS76383.1 - 0.00051 20.6 0.0 0.1 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ETS76383.1 - 0.0016 18.2 1.2 0.09 12.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 ETS76383.1 - 0.0023 17.0 0.2 0.15 11.0 0.3 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein Dynamin_N PF00350.23 ETS76383.1 - 0.0056 16.8 1.1 0.4 10.7 0.1 2.5 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 ETS76383.1 - 0.0061 16.8 0.6 2 8.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 ETS76383.1 - 0.029 14.1 0.2 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 ETS76383.1 - 0.045 13.5 0.3 2.8 7.7 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 ETS76383.1 - 0.061 12.8 0.1 9.2 5.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ETS76383.1 - 0.065 13.6 0.0 5.8 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 ETS76383.1 - 0.079 13.1 0.7 0.93 9.5 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 ETS76383.1 - 0.08 12.9 0.7 0.34 10.8 0.1 2.2 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 ETS76383.1 - 0.11 12.7 0.8 31 4.8 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 ETS76383.1 - 0.13 11.6 0.1 17 4.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family CPP1-like PF11833.8 ETS76383.1 - 0.72 9.5 5.2 2.3 7.8 0.0 3.0 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MWFE PF15879.5 ETS76383.1 - 1.2 9.4 3.9 2 8.6 0.3 3.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit DUF2841 PF11001.8 ETS76384.1 - 1.9e-40 137.7 2.4 3e-40 137.1 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) PPR_2 PF13041.6 ETS76385.1 - 4.9e-22 77.9 6.6 3.3e-15 56.0 0.2 4.2 3 1 1 4 4 4 3 PPR repeat family PPR_long PF17177.4 ETS76385.1 - 2.3e-09 36.9 0.3 1.3e-08 34.5 0.6 2.2 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 ETS76385.1 - 6.6e-09 35.7 3.0 0.00023 21.1 0.1 3.5 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 ETS76385.1 - 0.032 14.5 0.0 0.032 14.5 0.0 4.8 6 0 0 6 6 6 0 PPR repeat PPR_1 PF12854.7 ETS76385.1 - 0.063 13.0 3.3 8 6.3 0.1 4.2 5 0 0 5 5 5 0 PPR repeat DUF1230 PF06799.11 ETS76385.1 - 0.078 13.1 0.3 1.7 8.8 0.1 2.5 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 DUF719 PF05334.13 ETS76385.1 - 0.51 10.5 5.2 0.13 12.5 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF719) TPR_10 PF13374.6 ETS76386.1 - 8.9e-21 73.1 0.1 8.3e-10 38.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 ETS76386.1 - 5.9e-17 61.7 0.4 2.3e-14 53.4 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 ETS76386.1 - 0.0013 18.6 0.3 0.33 11.1 0.1 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 ETS76386.1 - 0.0021 17.8 0.0 0.46 10.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 ETS76386.1 - 0.006 16.6 0.0 0.25 11.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 ETS76386.1 - 0.032 14.4 0.1 0.85 10.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 ETS76386.1 - 0.064 13.7 0.0 12 6.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 ETS76386.1 - 0.13 12.6 0.3 20 5.7 0.0 2.4 2 0 0 2 2 2 0 PPR repeat AA_permease PF00324.21 ETS76387.1 - 5.1e-138 460.6 35.9 6.2e-138 460.4 35.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS76387.1 - 3e-40 138.4 37.0 3.9e-40 138.0 37.0 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 ETS76387.1 - 0.2 10.4 0.1 0.36 9.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Pkinase PF00069.25 ETS76388.1 - 1.4e-39 136.1 0.0 1.9e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS76388.1 - 7.9e-28 97.4 0.0 1.2e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS76388.1 - 0.002 17.5 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ETS76388.1 - 0.0094 15.9 0.1 0.86 9.5 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Na_H_Exchanger PF00999.21 ETS76389.1 - 7.4e-73 245.5 37.4 9e-73 245.2 37.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TERF2_RBM PF16772.5 ETS76389.1 - 0.023 14.1 0.1 0.066 12.6 0.1 1.8 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif DUF4220 PF13968.6 ETS76389.1 - 0.77 9.1 5.3 0.11 11.9 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) PepSY_TM PF03929.16 ETS76389.1 - 0.96 9.1 5.9 2.9 7.5 5.9 1.8 1 1 0 1 1 1 0 PepSY-associated TM region MFS_2 PF13347.6 ETS76390.1 - 7.2e-13 47.9 9.6 1.4e-12 46.9 3.7 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 ETS76390.1 - 1.3e-07 30.9 47.4 5.9e-06 25.4 30.6 3.5 1 1 2 3 3 3 2 Major Facilitator Superfamily PUCC PF03209.15 ETS76390.1 - 0.00015 20.9 5.6 0.00098 18.2 3.5 2.5 2 0 0 2 2 2 1 PUCC protein GH131_N PF18271.1 ETS76391.1 - 1.2e-62 212.0 3.2 1.4e-62 211.7 3.2 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 ETS76391.1 - 0.0055 16.6 6.0 0.012 15.5 6.1 1.6 1 1 0 1 1 1 1 Polysaccharide lyase CAP_N PF01213.19 ETS76392.1 - 0.085 12.3 1.0 0.12 11.9 1.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SLATT_fungal PF18142.1 ETS76392.1 - 1.6 8.7 6.1 2.8 7.9 6.1 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Velvet PF11754.8 ETS76393.1 - 2.3e-58 198.1 0.3 1.5e-38 133.1 0.1 2.1 1 1 1 2 2 2 2 Velvet factor E1_dh PF00676.20 ETS76394.1 - 1.3e-114 382.2 0.2 1.6e-114 381.9 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 ETS76394.1 - 0.0017 17.6 0.1 0.0032 16.7 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Hemocyanin_C PF03723.14 ETS76394.1 - 0.12 11.6 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Hemocyanin, ig-like domain DUF1770 PF08589.10 ETS76395.1 - 6.1e-37 126.6 0.5 7.8e-37 126.2 0.5 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) WHIM1 PF15612.6 ETS76396.1 - 1.2e-05 24.7 0.0 2.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF2981 PF11200.8 ETS76396.1 - 0.078 12.7 3.9 0.13 12.0 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) eRF1_2 PF03464.15 ETS76397.1 - 1.6e-45 154.7 0.0 2.6e-45 154.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 ETS76397.1 - 1.6e-40 138.1 0.6 3.3e-40 137.1 0.6 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 ETS76397.1 - 9e-22 77.5 0.0 1.5e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 ETS76397.1 - 6.4e-10 39.4 0.2 4.1e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 ETS76397.1 - 1e-08 35.5 0.0 1.8e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor PDT PF00800.18 ETS76398.1 - 2.6e-57 193.6 0.0 3.4e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 ETS76398.1 - 0.0013 18.5 0.1 0.0074 16.0 0.0 2.2 2 0 0 2 2 2 1 ACT domain AMP-binding PF00501.28 ETS76399.1 - 1.1e-291 966.4 0.0 2.2e-73 247.3 0.0 4.4 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 ETS76399.1 - 3.2e-241 800.8 0.0 3.5e-41 141.3 0.0 7.7 7 1 0 7 7 7 7 Condensation domain PP-binding PF00550.25 ETS76399.1 - 2.3e-54 181.6 3.3 4.5e-15 55.7 0.0 5.0 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ETS76399.1 - 5e-06 27.4 0.0 0.17 12.9 0.0 4.9 4 1 0 4 4 4 1 AMP-binding enzyme C-terminal domain DUF5122 PF17164.4 ETS76399.1 - 0.0007 19.8 6.4 12 6.3 0.1 4.9 4 0 0 4 4 4 3 Domain of unknown function (DUF5122) beta-propeller ABC_tran PF00005.27 ETS76400.1 - 8.8e-45 152.6 0.0 2.5e-25 89.6 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS76400.1 - 2.5e-32 112.7 41.7 6.1e-31 108.1 16.7 3.0 3 1 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.6 ETS76400.1 - 4.6e-11 43.1 0.1 0.0056 16.5 0.0 4.3 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETS76400.1 - 1.4e-10 41.0 0.0 0.00046 19.7 2.5 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ETS76400.1 - 5.8e-06 26.0 0.8 0.085 12.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 ETS76400.1 - 0.00053 20.5 0.3 0.93 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 ETS76400.1 - 0.0006 20.1 0.1 1.3 9.3 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 ETS76400.1 - 0.00084 19.1 0.0 0.31 10.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 ETS76400.1 - 0.0015 19.0 0.0 0.97 9.8 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 ETS76400.1 - 0.0039 17.1 1.9 0.43 10.5 0.1 2.8 3 0 0 3 3 3 1 RsgA GTPase ATP-synt_ab PF00006.25 ETS76400.1 - 0.0049 16.6 0.2 3.7 7.1 0.1 2.6 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 ETS76400.1 - 0.0053 16.8 0.0 3.6 7.7 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 ETS76400.1 - 0.0068 15.5 0.1 0.088 11.8 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.6 ETS76400.1 - 0.01 16.4 0.1 3.9 7.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ETS76400.1 - 0.012 16.0 2.1 0.48 10.8 0.1 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ETS76400.1 - 0.017 14.7 0.3 0.48 10.0 0.1 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ETS76400.1 - 0.019 14.3 0.1 7.3 5.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 ETS76400.1 - 0.036 14.2 0.0 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 ETS76400.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain PduV-EutP PF10662.9 ETS76400.1 - 0.062 13.0 0.9 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 ETS76400.1 - 0.083 12.7 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_ATPase PF09818.9 ETS76400.1 - 0.14 10.9 1.8 0.31 9.8 0.1 2.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class CbiA PF01656.23 ETS76400.1 - 0.17 11.9 0.0 11 6.1 0.0 2.7 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 ETS76400.1 - 0.18 11.3 0.1 9.1 5.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 ETS76400.1 - 0.69 9.5 2.1 23 4.5 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 ETS76400.1 - 2.7 7.9 3.9 18 5.2 0.1 3.0 3 0 0 3 3 3 0 Rad17 P-loop domain DUF3958 PF13125.6 ETS76402.1 - 0.012 15.8 1.3 0.034 14.3 1.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) Drf_FH3 PF06367.16 ETS76402.1 - 0.048 13.3 1.8 0.11 12.1 1.8 1.5 1 0 0 1 1 1 0 Diaphanous FH3 Domain PI_PP_I PF18363.1 ETS76402.1 - 0.091 13.0 2.0 0.41 10.8 0.9 2.6 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain Cytochrom_B562 PF07361.11 ETS76402.1 - 0.24 12.1 4.9 0.57 10.9 0.1 3.3 4 0 0 4 4 4 0 Cytochrome b562 Com_YlbF PF06133.11 ETS76402.1 - 0.49 11.0 4.6 7.2 7.3 0.4 2.8 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA IZUMO PF15005.6 ETS76402.1 - 1.3 9.5 4.1 2.3 8.8 0.1 2.9 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated HeLo PF14479.6 ETS76403.1 - 0.0013 18.6 0.2 0.0023 17.8 0.2 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation SH3_1 PF00018.28 ETS76404.1 - 1.1e-12 47.4 0.1 2.3e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ETS76404.1 - 4.6e-08 32.8 0.1 1e-07 31.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ETS76404.1 - 4.8e-08 32.6 0.1 8.1e-08 31.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain bZIP_2 PF07716.15 ETS76404.1 - 6.8e-06 26.1 4.4 6.8e-06 26.1 4.4 2.5 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 ETS76404.1 - 0.00013 22.0 4.8 0.00013 22.0 4.8 2.5 3 0 0 3 3 3 1 bZIP transcription factor SH3_3 PF08239.11 ETS76404.1 - 0.014 15.7 0.9 0.032 14.5 0.9 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain ESP PF16590.5 ETS76404.1 - 0.038 14.2 1.7 0.054 13.8 0.1 2.0 2 0 0 2 2 2 0 Exocrine gland-secreting peptide Med3 PF11593.8 ETS76404.1 - 3 6.9 24.4 0.072 12.3 14.5 2.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Cullin PF00888.22 ETS76405.1 - 7.7e-176 586.3 3.7 1e-175 585.9 3.7 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ETS76405.1 - 1.6e-26 92.1 0.7 4.5e-26 90.7 0.7 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF2235 PF09994.9 ETS76407.1 - 2.1e-46 158.6 0.0 3.4e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MMR_HSR1 PF01926.23 ETS76407.1 - 0.00038 20.5 0.0 0.00077 19.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETS76407.1 - 0.0094 15.9 0.1 0.023 14.6 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase Roc PF08477.13 ETS76407.1 - 0.023 14.9 0.1 0.22 11.8 0.1 2.3 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 ETS76407.1 - 0.11 12.9 1.8 1.7 9.0 0.1 2.6 2 0 0 2 2 2 0 AAA ATPase domain Glyco_transf_22 PF03901.17 ETS76408.1 - 1.6e-76 258.2 14.5 2e-76 257.9 14.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PsaX PF08078.12 ETS76408.1 - 3.3 7.7 6.5 19 5.3 1.9 3.5 3 0 0 3 3 3 0 PsaX family Aminotran_3 PF00202.21 ETS76409.1 - 4.7e-124 414.1 0.0 5.4e-124 413.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 ETS76409.1 - 6.7e-05 22.3 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 ETS76409.1 - 0.0003 20.1 0.0 0.00044 19.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3543 PF12063.8 ETS76410.1 - 3.6e-95 318.1 2.3 5.6e-95 317.5 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 ETS76410.1 - 3.1e-59 200.5 0.0 5.6e-59 199.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS76410.1 - 4.5e-41 140.9 0.0 9.6e-41 139.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS76410.1 - 0.013 14.9 0.0 0.23 10.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like DUF3732 PF12532.8 ETS76410.1 - 0.23 11.0 1.9 0.44 10.1 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) RhoGAP PF00620.27 ETS76411.1 - 1.7e-39 135.1 0.0 2.7e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain MFS_1 PF07690.16 ETS76412.1 - 5.4e-18 65.0 15.1 5.4e-18 65.0 15.1 1.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Aa_trans PF01490.18 ETS76413.1 - 1.2e-28 99.9 35.4 1.5e-28 99.7 35.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein adh_short_C2 PF13561.6 ETS76414.1 - 1.6e-53 181.7 0.2 3.9e-53 180.4 0.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS76414.1 - 9.2e-34 116.6 0.2 2.5e-33 115.2 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS76414.1 - 1.4e-06 28.3 0.5 2.6e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 ETS76414.1 - 0.0028 17.2 0.1 0.069 12.6 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 ETS76414.1 - 0.068 13.6 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 ETS76414.1 - 0.086 13.4 0.1 0.18 12.4 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans_2 PF11951.8 ETS76415.1 - 1.7e-42 145.6 7.0 2.4e-42 145.1 7.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS76415.1 - 3.5e-14 52.6 26.8 5.2e-08 32.9 12.6 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1479 PF07350.12 ETS76416.1 - 2.1e-08 33.4 0.0 0.0011 17.9 0.0 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.13 ETS76416.1 - 4.1e-07 30.5 0.0 5.7e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.24 ETS76417.1 - 4.3e-72 243.4 25.0 5.1e-72 243.2 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS76417.1 - 5.6e-23 81.4 22.8 5.6e-23 81.4 22.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4951 PF16309.5 ETS76417.1 - 0.65 10.1 2.6 2.6 8.1 0.2 2.7 3 0 0 3 3 3 0 Domian of unknown function (DUF4951) adh_short PF00106.25 ETS76418.1 - 7.2e-19 68.0 0.0 3.9e-17 62.4 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS76418.1 - 1.7e-08 34.3 0.0 4.3e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Csm1_B PF18211.1 ETS76418.1 - 0.00033 20.4 0.0 0.00067 19.4 0.0 1.5 1 0 0 1 1 1 1 Csm1 subunit domain B KR PF08659.10 ETS76418.1 - 0.00053 20.0 0.1 0.0012 18.7 0.0 1.6 2 0 0 2 2 2 1 KR domain Spectrin_like PF18373.1 ETS76418.1 - 0.052 13.6 0.0 0.13 12.4 0.0 1.6 2 0 0 2 2 2 0 Spectrin like domain TIR-like PF10137.9 ETS76418.1 - 0.19 11.7 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain FAD_binding_4 PF01565.23 ETS76420.1 - 3.3e-22 78.7 1.9 8.6e-22 77.4 1.9 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS76420.1 - 1.5e-12 47.4 0.1 3.4e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Ank_4 PF13637.6 ETS76421.1 - 0.018 15.6 0.0 4.9 7.8 0.0 3.4 4 0 0 4 4 4 0 Ankyrin repeats (many copies) FHA_2 PF17913.1 ETS76421.1 - 0.039 14.2 0.1 0.068 13.4 0.1 1.4 1 0 0 1 1 1 0 FHA domain F-box PF00646.33 ETS76422.1 - 0.00088 19.1 0.5 0.0028 17.5 0.5 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ETS76422.1 - 0.0033 17.3 0.1 0.0087 15.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like Glyco_hydro_18 PF00704.28 ETS76422.1 - 0.0065 16.2 0.2 0.013 15.2 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Terminase_4 PF05119.12 ETS76423.1 - 0.12 12.9 0.2 1 9.9 0.2 2.5 3 0 0 3 3 3 0 Phage terminase, small subunit TPR_10 PF13374.6 ETS76425.1 - 2.9e-37 125.5 9.9 3.4e-08 33.1 0.3 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 ETS76425.1 - 4.7e-33 113.3 9.4 3.1e-14 53.0 0.0 3.6 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 ETS76425.1 - 1.3e-07 31.2 2.6 3.5 8.0 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 ETS76425.1 - 3.9e-06 26.7 3.8 0.17 12.2 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS76425.1 - 8.1e-05 22.1 7.0 0.00011 21.7 4.5 2.1 1 1 1 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 ETS76425.1 - 0.00012 21.9 8.3 1.2 9.3 0.0 6.1 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 ETS76425.1 - 0.00012 21.7 0.1 5.3 7.0 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat zf-C2H2_4 PF13894.6 ETS76425.1 - 0.0017 19.1 11.9 3.9 8.6 0.1 4.7 4 0 0 4 4 4 1 C2H2-type zinc finger TPR_17 PF13431.6 ETS76425.1 - 0.0066 16.8 0.1 45 4.7 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 ETS76425.1 - 0.015 15.7 12.8 0.051 14.1 0.0 4.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type TPR_19 PF14559.6 ETS76425.1 - 0.033 14.7 3.9 1.3 9.5 0.6 4.4 3 1 2 5 5 5 0 Tetratricopeptide repeat zf-Di19 PF05605.12 ETS76425.1 - 0.045 14.0 4.6 2.6 8.4 0.5 3.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding TPR_4 PF07721.14 ETS76425.1 - 0.052 14.2 0.4 38 5.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Tn7_Tnp_TnsA_C PF08721.11 ETS76425.1 - 0.093 13.4 3.6 27 5.5 0.0 3.9 3 0 0 3 3 3 0 TnsA endonuclease C terminal zf-H2C2_2 PF13465.6 ETS76425.1 - 0.19 12.2 1.6 27 5.4 0.1 3.0 2 0 0 2 2 2 0 Zinc-finger double domain Glyco_hydro_18 PF00704.28 ETS76426.1 - 2.1e-71 241.2 3.2 2.9e-71 240.7 3.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ank_4 PF13637.6 ETS76428.1 - 2.4e-11 43.9 1.0 0.00067 20.2 0.1 3.8 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS76428.1 - 5.8e-08 33.2 1.7 1.4e-05 25.6 0.7 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS76428.1 - 2.6e-07 30.8 0.6 4.8e-05 23.6 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS76428.1 - 9.2e-07 28.7 0.5 0.0091 16.4 0.0 4.1 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 ETS76428.1 - 0.015 15.7 0.6 0.29 11.7 0.1 3.0 3 0 0 3 3 3 0 Ankyrin repeat LysM PF01476.20 ETS76429.1 - 4.7e-13 49.0 0.2 0.00015 21.8 0.1 4.8 5 0 0 5 5 5 3 LysM domain LysM PF01476.20 ETS76430.1 - 1e-16 60.7 0.7 0.0029 17.6 0.1 5.6 4 2 2 6 6 6 5 LysM domain Herpes_TK_C PF08465.10 ETS76430.1 - 0.19 11.5 0.8 12 5.7 0.1 2.3 2 0 0 2 2 2 0 Thymidine kinase from Herpesvirus C-terminal ABC_tran PF00005.27 ETS76431.1 - 5.6e-43 146.7 0.0 7.2e-23 81.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS76431.1 - 7.4e-36 124.2 34.0 3.2e-18 66.4 12.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ETS76431.1 - 3.9e-11 42.8 0.8 0.13 11.7 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETS76431.1 - 9.4e-08 32.2 0.0 0.021 14.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ETS76431.1 - 3.7e-06 27.3 0.3 0.23 11.7 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ETS76431.1 - 3.9e-06 27.4 0.2 0.018 15.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 ETS76431.1 - 9.2e-06 26.3 0.7 0.017 15.6 0.4 2.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ETS76431.1 - 2.6e-05 23.9 0.8 0.18 11.6 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 ETS76431.1 - 4.2e-05 23.4 1.7 0.025 14.3 0.2 3.3 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 ETS76431.1 - 8.9e-05 22.5 0.1 0.079 12.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 ETS76431.1 - 0.00028 20.5 2.0 0.0021 17.7 0.1 2.6 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 ETS76431.1 - 0.0014 18.7 0.3 0.093 12.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 ETS76431.1 - 0.0016 18.6 0.5 0.042 13.9 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_7 PF12775.7 ETS76431.1 - 0.0023 17.5 0.1 2.3 7.7 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region T2SSE PF00437.20 ETS76431.1 - 0.0036 16.4 0.1 0.032 13.3 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 ETS76431.1 - 0.0038 17.6 0.0 2.3 8.7 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 ETS76431.1 - 0.012 15.4 1.5 0.62 9.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ETS76431.1 - 0.019 14.3 0.4 0.47 9.7 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 ETS76431.1 - 0.075 12.9 0.5 0.46 10.4 0.1 2.4 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea TrwB_AAD_bind PF10412.9 ETS76431.1 - 0.091 11.7 2.6 0.47 9.3 0.5 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 ETS76431.1 - 0.12 12.2 1.0 9.7 6.1 0.2 2.6 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 ETS76431.1 - 0.2 11.6 0.6 2.9 7.9 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 ETS76431.1 - 0.25 10.5 1.0 12 5.0 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 ETS76431.1 - 0.52 10.2 2.6 2 8.3 0.1 2.7 3 0 0 3 3 3 0 NTPase AAA_19 PF13245.6 ETS76431.1 - 0.57 10.5 2.9 1.1 9.6 0.3 2.6 3 0 0 3 3 3 0 AAA domain Zn_clus PF00172.18 ETS76432.1 - 6.1e-08 32.7 11.7 1.2e-07 31.7 11.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.20 ETS76433.1 - 3.1e-44 151.7 2.1 3.7e-44 151.5 2.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS76433.1 - 1.5e-09 37.8 6.9 3.5e-09 36.7 2.9 2.1 2 0 0 2 2 2 2 Amidohydrolase family Peptidase_S10 PF00450.22 ETS76434.1 - 3.9e-85 286.8 0.0 4.9e-85 286.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Say1_Mug180 PF10340.9 ETS76434.1 - 0.21 10.4 0.0 0.4 9.5 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase Peptidase_S10 PF00450.22 ETS76435.1 - 1e-46 160.2 0.0 1.3e-46 159.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ribonuc_L-PSP PF01042.21 ETS76436.1 - 1e-27 96.5 0.0 1.1e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.16 ETS76437.1 - 1.6e-18 66.8 49.3 3e-11 42.9 32.0 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily CytB6-F_Fe-S PF08802.10 ETS76437.1 - 3.1 7.9 0.0 3.1 7.9 0.0 3.4 4 0 0 4 4 4 0 Cytochrome B6-F complex Fe-S subunit Aminotran_1_2 PF00155.21 ETS76438.1 - 2.7e-42 145.2 0.0 3.5e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 ETS76438.1 - 0.16 10.5 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Peptidase_S10 PF00450.22 ETS76439.1 - 6.3e-78 263.0 0.0 8.2e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Amidohydro_1 PF01979.20 ETS76440.1 - 6.5e-34 117.8 0.0 8.1e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS76440.1 - 2.8e-09 37.0 0.1 2.1e-08 34.1 0.1 2.2 2 1 0 2 2 2 1 Amidohydrolase family Peptidase_S10 PF00450.22 ETS76441.1 - 1.6e-32 113.5 0.0 2.2e-31 109.7 0.0 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase PEP_mutase PF13714.6 ETS76442.1 - 3.2e-46 157.7 0.6 3.7e-46 157.5 0.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 ETS76442.1 - 4.9e-20 71.5 1.9 7.1e-20 71.0 1.9 1.2 1 0 0 1 1 1 1 Isocitrate lyase family EIIBC-GUT_N PF03612.14 ETS76442.1 - 0.053 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Zeta_toxin PF06414.12 ETS76443.1 - 1.3e-40 138.8 0.0 1.9e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 ETS76443.1 - 0.0073 16.5 0.1 0.016 15.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 ETS76443.1 - 0.059 13.4 0.0 0.09 12.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 ETS76443.1 - 0.087 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Opy2 PF09463.10 ETS76444.1 - 5.9 7.3 12.3 0.73 10.2 6.7 2.3 2 1 0 2 2 2 0 Opy2 protein zf-RING_2 PF13639.6 ETS76444.1 - 6.3 7.2 14.6 3.3 8.1 2.5 2.6 2 1 0 2 2 2 0 Ring finger domain DUF2975 PF11188.8 ETS76445.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) BTB PF00651.31 ETS76446.1 - 0.00013 22.1 0.0 0.00029 21.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.7 ETS76447.1 - 1.9e-06 27.6 0.4 9.5e-06 25.4 0.2 2.3 2 0 0 2 2 2 1 F-box-like RNA_lig_T4_1 PF09511.10 ETS76447.1 - 0.0047 16.8 0.1 0.0095 15.8 0.1 1.4 1 0 0 1 1 1 1 RNA ligase F-box PF00646.33 ETS76447.1 - 0.0055 16.5 0.0 0.027 14.4 0.0 2.3 2 0 0 2 2 2 1 F-box domain p450 PF00067.22 ETS76448.1 - 9e-55 186.2 0.0 1.3e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BTB PF00651.31 ETS76449.1 - 0.00048 20.3 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Zn_clus PF00172.18 ETS76450.1 - 0.022 14.9 5.2 1.2 9.3 0.9 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF498 PF04430.14 ETS76450.1 - 0.22 11.6 0.4 1.1 9.4 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) RNA_pol_I_A49 PF06870.12 ETS76451.1 - 1.9e-89 300.3 0.1 3e-89 299.6 0.0 1.3 2 0 0 2 2 2 1 A49-like RNA polymerase I associated factor GARP PF16731.5 ETS76451.1 - 0.87 9.2 7.2 1.3 8.7 7.2 1.2 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma GARS_A PF01071.19 ETS76455.1 - 1.6e-81 272.7 0.0 2.9e-81 271.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 ETS76455.1 - 3.1e-34 118.3 0.1 7.9e-34 117.0 0.1 1.7 2 0 0 2 2 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 ETS76455.1 - 5.4e-33 113.6 0.0 1.7e-32 112.0 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 ETS76455.1 - 7.7e-27 93.4 0.8 1.7e-26 92.3 0.8 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 ETS76455.1 - 3.2e-13 50.1 2.0 1.1e-12 48.5 2.0 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 ETS76455.1 - 3.5e-05 23.5 0.0 6.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 ETS76455.1 - 0.00037 20.6 0.0 0.00085 19.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 ETS76455.1 - 0.0027 17.2 0.0 0.0051 16.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.10 ETS76455.1 - 0.007 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 ETS76455.1 - 0.011 15.3 0.1 0.041 13.5 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 ETS76455.1 - 0.03 13.6 0.1 0.099 11.9 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 ETS76455.1 - 0.037 13.6 0.0 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain DUF364 PF04016.12 ETS76455.1 - 0.13 11.9 0.1 1.3 8.6 0.1 2.3 2 0 0 2 2 2 0 Putative heavy-metal chelation CoaE PF01121.20 ETS76456.1 - 1e-42 145.9 0.0 3.3e-42 144.2 0.0 1.8 1 1 0 1 1 1 1 Dephospho-CoA kinase FixP_N PF14715.6 ETS76456.1 - 0.014 15.1 0.1 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP AAA_18 PF13238.6 ETS76456.1 - 0.015 15.9 0.8 0.29 11.7 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ETS76456.1 - 0.046 13.9 0.0 0.68 10.1 0.0 2.6 1 1 0 1 1 1 0 AAA domain eIF-5_eIF-2B PF01873.17 ETS76458.1 - 6.2e-37 126.0 0.0 1.4e-36 124.9 0.0 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 ETS76458.1 - 3.5e-19 68.7 0.8 3.5e-19 68.7 0.8 2.9 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon DUF3797 PF12677.7 ETS76458.1 - 0.028 14.3 0.6 0.073 13.0 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) Zn-ribbon_8 PF09723.10 ETS76458.1 - 0.14 12.3 0.4 0.28 11.3 0.4 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Rho_N PF07498.12 ETS76458.1 - 0.14 12.1 2.7 0.68 9.9 0.1 2.9 3 0 0 3 3 3 0 Rho termination factor, N-terminal domain Nudix_N_2 PF14803.6 ETS76458.1 - 0.24 11.4 1.7 0.52 10.3 1.7 1.5 1 0 0 1 1 1 0 Nudix N-terminal DNA_pol_phi PF04931.13 ETS76458.1 - 5.8 4.9 11.0 11 3.9 11.0 1.4 1 0 0 1 1 1 0 DNA polymerase phi HLH PF00010.26 ETS76459.1 - 2.1e-12 46.8 0.3 5.6e-12 45.4 0.3 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GIT1_C PF12205.8 ETS76459.1 - 0.024 14.7 2.5 0.15 12.2 2.5 2.2 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Pox_A30L_A26L PF06086.12 ETS76459.1 - 0.15 11.8 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein CLTH PF10607.9 ETS76460.1 - 1.6e-30 105.9 0.0 2.5e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 ETS76460.1 - 0.019 14.9 0.0 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 LisH Cep57_CLD PF14073.6 ETS76460.1 - 0.021 14.8 0.1 0.039 14.0 0.1 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 DUF2063 PF09836.9 ETS76460.1 - 0.075 13.3 0.1 0.55 10.5 0.0 2.4 2 0 0 2 2 2 0 Putative DNA-binding domain CAF1 PF04857.20 ETS76461.1 - 1.9e-25 89.7 0.0 4.1e-13 49.2 0.0 2.1 1 1 1 2 2 2 2 CAF1 family ribonuclease NDUF_B12 PF08122.12 ETS76462.1 - 1.9e-26 91.9 1.2 2.7e-26 91.4 1.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Golgin_A5 PF09787.9 ETS76463.1 - 0.0013 18.3 7.4 0.002 17.6 7.4 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 Exonuc_VII_L PF02601.15 ETS76463.1 - 0.021 14.4 3.8 0.034 13.7 3.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1635 PF07795.11 ETS76463.1 - 0.036 13.9 5.9 0.062 13.2 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) PH_13 PF16652.5 ETS76463.1 - 0.14 12.0 1.1 0.24 11.2 1.1 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain IFT20 PF14931.6 ETS76463.1 - 1.3 9.3 11.8 15 5.8 10.7 2.7 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 FapA PF03961.13 ETS76463.1 - 1.7 7.1 4.0 2.5 6.6 4.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4527 PF15030.6 ETS76463.1 - 5.4 6.4 13.3 0.95 8.8 8.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4527) TMPIT PF07851.13 ETS76463.1 - 6.1 6.0 6.9 9.4 5.4 6.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Pyr_redox_2 PF07992.14 ETS76464.1 - 4e-42 144.5 0.0 4.8e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS76464.1 - 7.2e-12 45.7 0.2 1.6e-08 35.0 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS76464.1 - 2.9e-08 33.7 8.0 0.078 12.5 0.2 4.1 4 0 0 4 4 4 4 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS76464.1 - 2.1e-06 27.8 2.1 0.28 11.1 0.1 4.0 3 1 0 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ETS76464.1 - 0.0026 16.9 0.2 1.8 7.5 0.0 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein K_oxygenase PF13434.6 ETS76464.1 - 0.014 14.5 0.0 0.033 13.3 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 ETS76464.1 - 0.016 14.3 1.4 0.28 10.2 0.1 2.6 3 0 0 3 3 3 0 FAD binding domain Trp_halogenase PF04820.14 ETS76464.1 - 0.024 13.5 7.6 0.035 12.9 0.5 2.7 3 1 0 3 3 3 0 Tryptophan halogenase NAD_binding_8 PF13450.6 ETS76464.1 - 0.031 14.5 0.2 7.7 6.8 0.1 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ETS76464.1 - 0.084 12.1 0.2 6.1 6.0 0.1 2.2 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 ETS76464.1 - 0.14 11.5 0.7 0.19 11.0 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS76464.1 - 0.18 11.0 0.1 24 4.0 0.0 2.9 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 ETS76465.1 - 1.4e-11 43.9 0.0 2.2e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS76465.1 - 5.7e-09 35.9 9.3 1.1e-08 35.0 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N_2 PF13602.6 ETS76466.1 - 6e-19 69.4 0.0 1.1e-18 68.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ETS76466.1 - 1.1e-14 54.5 0.0 1.3e-12 47.8 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS76466.1 - 8.1e-05 22.5 0.0 0.00021 21.1 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 ETS76466.1 - 0.00017 22.0 0.1 0.00075 19.9 0.1 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 ETS76466.1 - 0.019 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 ETS76466.1 - 0.087 12.9 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Cupin_2 PF07883.11 ETS76467.1 - 8.2e-09 35.1 0.2 1.5e-08 34.2 0.2 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ETS76467.1 - 6.3e-06 25.9 0.1 7.8e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_7 PF12973.7 ETS76467.1 - 0.01 15.8 0.1 0.017 15.1 0.1 1.4 1 1 0 1 1 1 0 ChrR Cupin-like domain Peptidase_M28 PF04389.17 ETS76468.1 - 1.6e-28 99.8 0.0 3.5e-28 98.6 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ETS76468.1 - 9e-08 32.1 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 fn3 PF00041.21 ETS76468.1 - 0.0042 17.4 0.1 0.0088 16.4 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Peptidase_M42 PF05343.14 ETS76468.1 - 0.0044 16.1 0.0 0.0071 15.4 0.0 1.4 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase GMC_oxred_N PF00732.19 ETS76469.1 - 4.8e-32 111.5 0.0 1.6e-31 109.8 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS76469.1 - 9.6e-18 65.1 0.7 1.6e-17 64.3 0.7 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 ETS76469.1 - 5.9e-10 39.3 0.3 2.2e-05 24.2 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS76469.1 - 5e-08 32.5 0.1 0.00073 18.7 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 ETS76469.1 - 1.5e-06 27.2 0.3 1.1e-05 24.4 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 ETS76469.1 - 4.7e-06 26.7 0.1 1.2e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS76469.1 - 4.9e-06 26.0 0.1 1.4e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS76469.1 - 3.7e-05 22.9 0.1 6.4e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 ETS76469.1 - 4.1e-05 23.1 0.7 0.003 17.0 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS76469.1 - 0.00063 19.1 0.6 0.0077 15.5 1.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS76469.1 - 0.00084 18.7 1.1 0.0016 17.8 0.3 1.8 2 1 1 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 ETS76469.1 - 0.0022 18.5 0.1 0.037 14.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS76469.1 - 0.018 14.3 0.1 0.039 13.2 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 ETS76469.1 - 0.019 15.0 0.1 0.17 11.9 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 ETS76469.1 - 0.032 13.1 0.1 0.05 12.4 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 ETS76469.1 - 0.032 13.3 0.1 0.048 12.7 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A SBP_bac_1 PF01547.25 ETS76469.1 - 0.033 14.1 1.5 0.035 14.0 0.3 1.6 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein dCache_2 PF08269.11 ETS76471.1 - 0.058 12.6 1.1 0.097 11.8 1.1 1.2 1 0 0 1 1 1 0 Cache domain CorA PF01544.18 ETS76471.1 - 0.4 9.9 16.8 11 5.2 16.7 2.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein zf-C2H2_11 PF16622.5 ETS76472.1 - 0.0012 18.5 0.4 0.0023 17.7 0.4 1.4 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2 PF00096.26 ETS76472.1 - 0.0088 16.4 0.3 0.02 15.3 0.3 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS76472.1 - 0.05 14.4 0.3 0.12 13.3 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 ETS76472.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type ABC_tran PF00005.27 ETS76473.1 - 8.8e-34 117.0 0.0 6.5e-17 62.3 0.0 2.7 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ETS76473.1 - 1.9e-12 47.1 1.6 0.00017 21.1 0.0 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain RLI PF04068.15 ETS76473.1 - 3.5e-12 45.9 4.8 3.5e-12 45.9 4.8 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 ETS76473.1 - 7.2e-10 39.2 7.4 0.015 15.1 0.1 4.3 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ETS76473.1 - 5.6e-07 29.9 0.0 0.00019 21.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ETS76473.1 - 1.6e-06 28.5 0.2 0.012 16.0 0.1 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS76473.1 - 3e-05 24.4 0.0 0.38 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Fer4 PF00037.27 ETS76473.1 - 4.5e-05 23.1 2.8 4.5e-05 23.1 2.8 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 ETS76473.1 - 7.8e-05 22.6 0.0 0.69 9.8 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase RNA_helicase PF00910.22 ETS76473.1 - 9.8e-05 22.7 0.2 0.12 12.8 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_23 PF13476.6 ETS76473.1 - 0.00012 22.7 0.2 0.027 15.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 ETS76473.1 - 0.00019 21.3 0.3 0.64 9.7 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 ETS76473.1 - 0.00027 21.1 0.1 0.97 9.6 0.1 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 ETS76473.1 - 0.00034 20.6 1.0 0.19 11.6 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_24 PF13479.6 ETS76473.1 - 0.00043 20.1 0.3 0.07 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 ETS76473.1 - 0.0006 19.5 3.3 0.052 13.2 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_29 PF13555.6 ETS76473.1 - 0.0009 18.9 0.2 0.72 9.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Fer4_10 PF13237.6 ETS76473.1 - 0.0011 19.0 8.5 0.016 15.3 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Rad17 PF03215.15 ETS76473.1 - 0.0013 18.7 0.3 0.51 10.2 0.1 3.1 3 0 0 3 3 3 1 Rad17 P-loop domain Fer4_6 PF12837.7 ETS76473.1 - 0.0018 18.3 1.2 0.0018 18.3 1.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 ETS76473.1 - 0.0018 18.4 10.2 0.004 17.3 10.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_18 PF13238.6 ETS76473.1 - 0.0024 18.4 0.0 3.6 8.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 ETS76473.1 - 0.0025 17.8 0.3 0.05 13.6 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 ETS76473.1 - 0.0042 15.8 3.0 0.0043 15.8 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 ETS76473.1 - 0.0075 15.8 0.8 0.12 11.9 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 ETS76473.1 - 0.011 16.0 0.2 2.2 8.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain Thymidylate_kin PF02223.17 ETS76473.1 - 0.012 15.3 0.7 1.5 8.5 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase AAA_30 PF13604.6 ETS76473.1 - 0.014 15.1 0.5 4.4 7.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain Fer4_7 PF12838.7 ETS76473.1 - 0.014 15.9 5.7 0.029 15.0 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.15 ETS76473.1 - 0.052 13.5 2.1 2.8 7.8 0.1 2.9 3 0 0 3 3 3 0 NTPase AAA_14 PF13173.6 ETS76473.1 - 0.057 13.5 0.1 24 4.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain Fer4_9 PF13187.6 ETS76473.1 - 0.058 13.6 10.3 0.13 12.5 10.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 ETS76473.1 - 0.093 13.7 0.2 0.093 13.7 0.2 2.7 2 0 0 2 2 1 0 4Fe-4S double cluster binding domain AAA_5 PF07728.14 ETS76473.1 - 0.11 12.5 1.4 3.2 7.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 ETS76473.1 - 0.11 11.6 0.5 13 4.8 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain MukB PF04310.12 ETS76473.1 - 0.12 12.2 0.2 9.5 5.9 0.0 2.3 2 0 0 2 2 2 0 MukB N-terminal Rad51 PF08423.11 ETS76473.1 - 0.17 11.1 0.0 0.37 10.0 0.0 1.5 1 0 0 1 1 1 0 Rad51 MMR_HSR1 PF01926.23 ETS76473.1 - 0.18 11.9 1.6 18 5.4 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF815 PF05673.13 ETS76473.1 - 0.18 10.9 0.1 16 4.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 ETS76473.1 - 0.35 10.4 0.9 9.2 5.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 ETS76473.1 - 0.88 9.3 2.7 0.87 9.3 0.0 2.3 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Fer4_2 PF12797.7 ETS76473.1 - 3.3 8.0 10.0 0.56 10.4 1.1 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain BTB PF00651.31 ETS76474.1 - 1.7e-05 25.0 0.0 3.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain HSV_VP16_C PF12149.8 ETS76474.1 - 0.21 11.7 0.4 0.44 10.7 0.4 1.4 1 0 0 1 1 1 0 Herpes simplex virus virion protein 16 C terminal Fungal_trans PF04082.18 ETS76475.1 - 1.5e-16 60.2 0.4 2.5e-16 59.5 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS76475.1 - 3.6e-08 33.4 9.9 6.5e-08 32.6 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3631 PF12307.8 ETS76475.1 - 0.062 13.5 0.1 5.9 7.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3631) MFS_1 PF07690.16 ETS76476.1 - 2.5e-41 141.8 20.8 2.5e-41 141.8 20.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS76476.1 - 2.3e-11 43.3 9.1 2.3e-11 43.3 9.1 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 ETS76476.1 - 5.4e-06 25.0 0.0 1.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 ETS76476.1 - 0.00025 19.6 4.1 0.0004 18.9 4.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CN_hydrolase PF00795.22 ETS76477.1 - 3.3e-44 151.2 0.2 3.9e-44 151.0 0.2 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Aldedh PF00171.22 ETS76478.1 - 1.4e-133 445.8 0.0 1.7e-133 445.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ETS76478.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) p450 PF00067.22 ETS76480.1 - 9e-21 74.1 0.0 8.6e-18 64.3 0.0 2.6 1 1 0 1 1 1 1 Cytochrome P450 DUF1633 PF07794.11 ETS76480.1 - 0.31 9.2 0.0 0.44 8.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Cupin_2 PF07883.11 ETS76481.1 - 3.1e-08 33.2 0.3 6e-08 32.3 0.3 1.4 1 0 0 1 1 1 1 Cupin domain UbiA PF01040.18 ETS76482.1 - 7.3e-36 123.8 16.3 9.8e-36 123.3 16.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family FAD_binding_4 PF01565.23 ETS76483.1 - 1.8e-29 102.2 0.8 2.8e-29 101.6 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.25 ETS76484.1 - 1e-06 28.4 0.0 0.044 13.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 ETS76484.1 - 0.0012 18.8 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ETS76484.1 - 0.019 14.5 0.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase p450 PF00067.22 ETS76485.1 - 8.7e-42 143.4 0.0 1.3e-40 139.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 HET PF06985.11 ETS76486.1 - 2.1e-24 86.5 0.0 3.3e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tho1_MOS11_C PF18592.1 ETS76486.1 - 0.013 15.3 0.0 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain MFS_1 PF07690.16 ETS76487.1 - 2.5e-38 131.9 42.5 7.6e-38 130.3 42.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS76487.1 - 2.4e-17 62.6 15.9 3e-17 62.3 15.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS76487.1 - 2.1e-14 53.3 14.5 2.1e-14 53.3 14.5 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 ETS76487.1 - 0.00047 18.7 6.2 0.00086 17.8 6.2 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector Zn_clus PF00172.18 ETS76488.1 - 1.2e-05 25.3 10.3 2.8e-05 24.1 10.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_2 PF00891.18 ETS76489.1 - 8.4e-21 74.2 0.0 1.5e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain HTH_24 PF13412.6 ETS76489.1 - 0.00017 21.1 0.1 0.00028 20.4 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_IclR PF09339.10 ETS76489.1 - 0.0068 16.2 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain Dimerisation2 PF16864.5 ETS76489.1 - 0.024 14.6 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain TFIIE_alpha PF02002.17 ETS76489.1 - 0.024 14.5 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit CheR PF01739.18 ETS76489.1 - 0.037 13.5 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MarR_2 PF12802.7 ETS76489.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_AsnC-type PF13404.6 ETS76489.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Cupin_3 PF05899.12 ETS76490.1 - 0.067 12.9 0.5 0.49 10.1 0.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_2 PF07883.11 ETS76490.1 - 0.26 11.0 2.0 8.9 6.1 2.0 2.2 1 1 0 1 1 1 0 Cupin domain Sugar_tr PF00083.24 ETS76492.1 - 1.6e-73 248.1 22.8 1.8e-73 247.9 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS76492.1 - 9e-15 54.4 46.7 1.4e-14 53.8 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_18 PF00704.28 ETS76494.1 - 2.3e-63 214.8 3.4 3.6e-63 214.2 3.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ETS76494.1 - 2.5e-11 43.9 16.9 2.5e-11 43.9 16.9 3.8 3 1 1 4 4 4 2 Chitin recognition protein LysM PF01476.20 ETS76495.1 - 2e-21 75.8 0.3 7.8e-07 29.1 0.0 5.1 5 0 0 5 5 5 3 LysM domain DUF1153 PF06627.11 ETS76495.1 - 0.062 13.4 0.0 5.2 7.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1153) CNDH2_M PF16869.5 ETS76495.1 - 0.26 12.0 1.6 3.1 8.5 1.6 2.2 1 1 0 1 1 1 0 PF16858 Methyltransf_2 PF00891.18 ETS76496.1 - 2e-29 102.4 0.0 2.7e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 ETS76496.1 - 0.0013 19.4 0.0 0.0033 18.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DUF4338 PF14236.6 ETS76496.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4338) Methyltransf_12 PF08242.12 ETS76496.1 - 0.1 13.4 0.0 0.22 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 ETS76496.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ank_2 PF12796.7 ETS76497.1 - 1e-33 115.7 0.0 2.4e-13 50.5 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS76497.1 - 5.2e-14 52.4 0.3 0.00015 22.2 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 ETS76497.1 - 6.1e-14 51.7 0.3 2.2e-05 24.7 0.0 5.7 5 0 0 5 5 4 3 Ankyrin repeat Ank_5 PF13857.6 ETS76497.1 - 1.2e-10 41.5 0.3 8.5e-06 26.0 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS76497.1 - 8.9e-08 31.8 0.0 0.00055 20.2 0.0 4.9 5 0 0 5 5 3 1 Ankyrin repeat NACHT PF05729.12 ETS76497.1 - 2.2e-07 31.0 0.0 5.5e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS76497.1 - 3e-06 27.7 0.0 1.1e-05 25.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS76497.1 - 7.1e-05 23.1 0.0 0.00024 21.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain SesA PF17107.5 ETS76497.1 - 0.00038 20.6 0.1 0.0014 18.8 0.1 2.0 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases ATPase_2 PF01637.18 ETS76497.1 - 0.00072 19.5 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 ETS76497.1 - 0.0019 18.2 0.0 0.4 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ETS76497.1 - 0.002 18.5 0.0 0.0063 16.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA PF00004.29 ETS76497.1 - 0.0022 18.4 0.0 0.018 15.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TPR_2 PF07719.17 ETS76497.1 - 0.075 13.2 0.5 25 5.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_14 PF13173.6 ETS76497.1 - 0.15 12.1 0.1 2 8.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain Baculo_PEP_C PF04513.12 ETS76497.1 - 4.4 7.3 6.0 0.94 9.5 1.8 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus KAP_NTPase PF07693.14 ETS76497.1 - 8 5.6 7.1 6.3 5.9 0.0 2.9 2 1 1 3 3 3 0 KAP family P-loop domain Lipase_GDSL_2 PF13472.6 ETS76498.1 - 3.7e-08 34.0 0.0 4.9e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS76498.1 - 0.025 14.6 0.0 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DCA16 PF15349.6 ETS76499.1 - 0.0039 16.8 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 DDB1- and CUL4-associated factor 16 NACHT PF05729.12 ETS76501.1 - 3.6e-05 23.8 1.0 0.14 12.1 0.0 3.2 2 1 1 3 3 3 2 NACHT domain Ank_4 PF13637.6 ETS76501.1 - 0.00028 21.4 0.0 0.031 14.9 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS76501.1 - 0.0014 18.9 0.0 0.13 12.7 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) AAA_22 PF13401.6 ETS76501.1 - 0.053 13.8 0.1 0.36 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ETS76501.1 - 0.056 14.0 0.0 0.34 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ETS76501.1 - 0.13 12.7 0.1 1.1 9.6 0.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 ETS76501.1 - 0.16 12.3 0.0 0.5 10.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TPR_12 PF13424.6 ETS76502.1 - 1e-25 89.8 15.9 1.6e-09 37.9 0.2 6.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 ETS76502.1 - 1.7e-21 74.5 8.0 2.4e-05 24.1 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 ETS76502.1 - 4.1e-18 64.4 8.0 8e-05 22.3 0.1 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 ETS76502.1 - 3.4e-13 49.0 9.0 0.00024 20.8 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat NB-ARC PF00931.22 ETS76502.1 - 1.4e-12 47.4 0.1 7.9e-12 44.9 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain TPR_8 PF13181.6 ETS76502.1 - 5.9e-12 44.8 5.6 0.01 16.0 0.0 6.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS76502.1 - 4.3e-10 39.5 2.8 4.9e-09 36.0 0.9 2.2 1 1 1 2 2 2 2 MalT-like TPR region TPR_16 PF13432.6 ETS76502.1 - 6e-09 36.4 0.9 1.9e-05 25.2 0.1 3.8 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 ETS76502.1 - 1.3e-08 34.2 8.6 0.012 15.6 0.1 6.0 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 ETS76502.1 - 2e-08 34.3 1.0 0.058 14.1 0.1 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 ETS76502.1 - 2.2e-07 30.4 1.2 0.0081 15.8 0.1 4.2 3 1 1 4 4 4 1 TPR repeat TPR_14 PF13428.6 ETS76502.1 - 5.3e-07 29.9 2.2 0.15 13.0 0.0 5.9 3 2 2 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 ETS76502.1 - 1.1e-06 28.5 0.1 0.6 10.6 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 ETS76502.1 - 1.6e-06 28.0 0.0 4.1e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_19 PF14559.6 ETS76502.1 - 1.9e-06 28.3 1.8 0.015 15.8 0.0 4.2 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 ETS76502.1 - 2.6e-05 24.4 0.3 0.42 11.4 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_16 PF13191.6 ETS76502.1 - 0.00099 19.5 0.3 0.0065 16.9 0.3 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS76502.1 - 0.0019 18.5 0.0 0.0062 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain ANAPC5 PF12862.7 ETS76502.1 - 0.007 16.4 1.0 0.025 14.7 0.1 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 5 DUF3856 PF12968.7 ETS76502.1 - 0.019 15.1 0.4 7.2 6.7 0.1 3.0 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 ETS76502.1 - 0.022 14.9 0.8 3.2 8.1 0.0 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 ETS76502.1 - 0.028 14.5 3.1 0.095 12.9 0.2 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.9 ETS76502.1 - 0.075 12.7 1.4 1.3 8.7 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.18 ETS76502.1 - 0.12 12.5 1.9 5.9 7.0 0.0 3.6 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain SPO22 PF08631.10 ETS76502.1 - 0.16 11.4 0.9 6.7 6.1 0.1 2.7 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like Glyco_hydro_125 PF06824.11 ETS76506.1 - 0.02 13.8 0.1 0.035 13.0 0.1 1.4 1 0 0 1 1 1 0 Metal-independent alpha-mannosidase (GH125) DUF4574 PF15141.6 ETS76506.1 - 0.021 14.7 0.2 3.6 7.6 0.0 2.9 2 1 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 CREPT PF16566.5 ETS76506.1 - 0.2 11.8 2.4 13 6.0 0.6 2.5 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour KxDL PF10241.9 ETS76506.1 - 1.6 9.1 5.3 0.72 10.2 1.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein Glyco_hydro_61 PF03443.14 ETS76507.1 - 7.3e-48 163.2 0.0 1.2e-47 162.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Hydantoinase_B PF02538.14 ETS76508.1 - 7e-213 707.7 0.1 9.7e-213 707.2 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 ETS76508.1 - 1.3e-104 349.6 0.0 2.7e-104 348.5 0.0 1.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ETS76508.1 - 1e-60 204.5 0.6 5.2e-59 198.9 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.9 ETS76508.1 - 0.035 13.8 0.1 0.083 12.6 0.1 1.7 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature ABC2_membrane_2 PF12679.7 ETS76509.1 - 0.054 12.8 0.3 0.054 12.8 0.3 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein FtsX PF02687.21 ETS76509.1 - 0.85 10.1 8.5 5.8 7.5 2.3 2.2 2 0 0 2 2 2 0 FtsX-like permease family T5orf172 PF10544.9 ETS76510.1 - 2.7e-14 53.6 0.5 6.5e-14 52.3 0.1 1.9 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 ETS76510.1 - 1.9e-08 34.9 0.4 3.8e-08 33.9 0.4 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 NAAA-beta PF15508.6 ETS76510.1 - 0.029 14.7 1.6 0.058 13.7 0.8 1.9 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase CCDC106 PF15794.5 ETS76510.1 - 0.4 10.4 1.2 6 6.5 0.4 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 eIF-6 PF01912.18 ETS76511.1 - 9.1e-81 270.0 0.7 1.2e-80 269.6 0.7 1.1 1 0 0 1 1 1 1 eIF-6 family ThiF PF00899.21 ETS76513.1 - 1.7e-33 116.0 0.0 2.4e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family FerA PF08165.11 ETS76514.1 - 0.042 13.8 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 FerA (NUC095) domain Cytochrom_C552 PF02335.15 ETS76514.1 - 0.63 8.9 2.6 1.2 8.0 2.6 1.3 1 0 0 1 1 1 0 Cytochrome c552 PNPase PF03726.14 ETS76514.1 - 0.93 10.0 6.3 3 8.4 4.8 2.4 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF4407 PF14362.6 ETS76514.1 - 3.8 6.8 9.0 4.9 6.4 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HD_3 PF13023.6 ETS76514.1 - 8.7 6.2 11.6 2 8.3 4.3 2.1 2 0 0 2 2 2 0 HD domain DUF2431 PF10354.9 ETS76515.1 - 3.2e-67 226.0 0.0 3.9e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Bac_luciferase PF00296.20 ETS76516.1 - 9.5e-63 212.5 0.0 1.2e-62 212.2 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase CDI PF02234.19 ETS76516.1 - 0.11 12.7 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Pectate_lyase_3 PF12708.7 ETS76517.1 - 9.5e-91 303.4 17.5 4.4e-83 278.4 9.4 4.1 4 2 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 ETS76517.1 - 1.2e-06 28.1 3.2 0.017 14.8 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Plasmodium_Vir PF05795.11 ETS76517.1 - 6.6 6.0 5.9 3.3 7.0 3.8 1.5 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Scs3p PF10261.9 ETS76518.1 - 5.9e-79 265.0 6.0 7.3e-79 264.7 6.0 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM VPS9 PF02204.18 ETS76519.1 - 2.4e-25 88.8 0.0 4.9e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CK2S PF15011.6 ETS76519.1 - 0.0075 16.2 0.1 0.031 14.2 0.0 2.0 2 0 0 2 2 2 1 Casein Kinase 2 substrate DUF5601 PF18151.1 ETS76519.1 - 0.028 14.7 0.1 0.077 13.3 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5601) Lipase_3 PF01764.25 ETS76520.1 - 2.1e-07 30.9 0.0 5.8e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) UPF0227 PF05728.12 ETS76520.1 - 0.003 17.5 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 ETS76520.1 - 0.0031 16.8 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS76520.1 - 0.0054 16.4 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS76520.1 - 0.011 16.3 1.6 0.053 14.1 0.1 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 ETS76520.1 - 0.045 13.5 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 ETS76520.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family CH PF00307.31 ETS76521.1 - 5.9e-47 158.4 0.1 2.6e-22 79.0 0.0 2.8 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 ETS76521.1 - 4.1e-23 81.3 0.5 2.7e-22 78.6 0.0 2.4 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 ETS76521.1 - 8.8e-13 47.9 0.1 1.9e-06 27.6 0.0 2.6 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 ETS76521.1 - 3.7e-06 26.4 0.3 0.00078 19.2 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 ETS76521.1 - 1.1e-05 25.8 1.8 1.1e-05 25.8 1.8 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 ETS76521.1 - 6.3e-05 22.8 1.3 0.0062 16.4 0.1 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ETS76521.1 - 9e-05 21.8 0.1 0.032 13.8 0.0 2.7 2 0 0 2 2 2 2 EF hand Spectrin PF00435.21 ETS76521.1 - 0.53 10.8 6.2 1.9 9.0 0.1 2.6 2 0 0 2 2 2 0 Spectrin repeat FAD-oxidase_C PF02913.19 ETS76522.1 - 8.2e-63 212.4 0.0 1.1e-62 211.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ETS76522.1 - 1.8e-36 124.9 0.2 3.5e-36 124.0 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain zf-Tim10_DDP PF02953.15 ETS76523.1 - 4.2e-22 77.6 3.4 5.6e-22 77.2 3.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribosomal_L23eN PF03939.13 ETS76524.1 - 1.3e-24 86.1 8.7 1.3e-24 86.1 8.7 2.2 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 ETS76524.1 - 1.7e-15 57.1 0.2 1.7e-15 57.1 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L23 Bmt2 PF11968.8 ETS76525.1 - 3.9e-90 301.5 0.0 4.8e-90 301.2 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 ETS76525.1 - 0.02 14.7 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF2989 PF11207.8 ETS76525.1 - 0.09 12.5 0.5 0.15 11.8 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) HAD_2 PF13419.6 ETS76526.1 - 0.0044 17.1 0.0 0.0077 16.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ETS76526.1 - 0.014 15.4 0.0 0.072 13.2 0.0 2.1 1 1 1 2 2 2 0 HAD-hyrolase-like HAD PF12710.7 ETS76526.1 - 0.097 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 ETS76527.1 - 2.5e-55 187.7 0.0 3.7e-55 187.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS76527.1 - 1.6e-33 116.1 0.0 2.5e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS76527.1 - 6.5e-12 45.4 0.0 7.7e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 ETS76527.1 - 0.0068 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CusF_Ec PF11604.8 ETS76527.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF Ribosomal_L7Ae PF01248.26 ETS76527.1 - 0.18 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Aa_trans PF01490.18 ETS76528.1 - 5.6e-60 203.2 33.1 7e-60 202.8 33.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FAD_binding_4 PF01565.23 ETS76529.1 - 4.9e-34 117.1 4.1 1.2e-33 115.8 4.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS76529.1 - 6.9e-07 29.3 0.3 2.1e-06 27.7 0.3 1.9 1 0 0 1 1 1 1 Berberine and berberine like CN_hydrolase PF00795.22 ETS76530.1 - 1.8e-42 145.5 0.7 2.1e-42 145.3 0.7 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase adh_short PF00106.25 ETS76531.1 - 1e-24 87.1 0.0 2.8e-20 72.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS76531.1 - 6.5e-12 45.5 0.0 7.3e-09 35.5 0.0 2.4 1 1 2 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS76531.1 - 4.9e-05 23.3 0.1 8.2e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 KR domain PTR2 PF00854.21 ETS76533.1 - 9e-80 268.4 10.8 1.4e-79 267.8 10.8 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 ETS76533.1 - 1e-05 24.7 29.5 0.0045 16.0 8.5 2.9 3 0 0 3 3 3 2 Major Facilitator Superfamily PUCC PF03209.15 ETS76533.1 - 0.029 13.4 10.0 0.14 11.2 1.8 2.3 2 0 0 2 2 2 0 PUCC protein GAGE PF05831.11 ETS76533.1 - 0.18 12.3 0.1 0.42 11.2 0.1 1.6 1 0 0 1 1 1 0 GAGE protein DUF3425 PF11905.8 ETS76534.1 - 1.8e-09 37.6 0.3 4e-09 36.5 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) RasGAP PF00616.19 ETS76535.1 - 2.3e-58 197.3 0.1 1.5e-57 194.7 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 ETS76535.1 - 3.7e-29 101.6 5.0 3.7e-29 101.6 5.0 2.7 2 0 0 2 2 2 1 RasGAP C-terminus Fibin PF15819.5 ETS76535.1 - 8.8 6.0 8.2 1.3 8.7 1.9 2.7 4 0 0 4 4 4 0 Fin bud initiation factor homologue Amidohydro_1 PF01979.20 ETS76536.1 - 8.5e-20 71.3 2.0 3.6e-19 69.3 2.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS76536.1 - 2.3e-13 50.5 4.6 3e-08 33.6 0.3 2.8 1 1 1 2 2 2 2 Amidohydrolase family Pkinase PF00069.25 ETS76537.1 - 6.8e-30 104.3 0.0 9.8e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS76537.1 - 7e-16 58.3 0.0 1.2e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 ETS76537.1 - 3e-07 30.9 0.0 0.062 13.9 0.0 3.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS76537.1 - 2.5e-05 24.3 0.4 0.99 10.2 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 ETS76537.1 - 6.3e-05 23.4 0.0 0.2 12.3 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS76537.1 - 0.00011 22.4 2.5 0.27 11.7 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Kinase-like PF14531.6 ETS76537.1 - 0.0026 17.1 0.0 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Ank_5 PF13857.6 ETS76537.1 - 0.091 13.1 0.1 48 4.4 0.0 3.6 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Fungal_trans PF04082.18 ETS76540.1 - 5.4e-22 78.1 1.2 1.2e-21 77.0 1.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 ETS76541.1 - 4.5e-18 65.3 1.7 4.8e-18 65.2 1.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 ETS76542.1 - 1.1e-33 116.8 2.8 4.5e-30 104.9 2.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS76542.1 - 8e-12 44.7 4.1 1.1e-09 37.7 2.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.12 ETS76543.1 - 1.3e-29 102.3 1.0 2.4e-29 101.4 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS76543.1 - 3e-25 88.7 0.1 4.5e-25 88.1 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS76543.1 - 1.9e-11 43.8 0.3 3.1e-11 43.1 0.3 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ETS76543.1 - 7.6e-08 33.5 0.0 2.1e-07 32.1 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ETS76543.1 - 0.001 18.5 1.1 0.0016 17.8 1.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 ETS76543.1 - 0.0015 17.8 0.1 0.009 15.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS76543.1 - 0.0033 16.2 0.5 0.0045 15.7 0.5 1.1 1 0 0 1 1 1 1 HI0933-like protein PALP PF00291.25 ETS76543.1 - 0.0052 16.2 0.5 0.0085 15.5 0.5 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pyr_redox PF00070.27 ETS76543.1 - 0.021 15.4 0.7 0.089 13.4 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.21 ETS76543.1 - 0.036 14.1 1.1 0.2 11.7 1.1 2.1 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ETS76543.1 - 0.1 12.2 0.3 0.18 11.4 0.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1188 PF06690.11 ETS76543.1 - 0.11 12.0 0.0 14 5.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1188) Zn_clus PF00172.18 ETS76544.1 - 4.9e-07 29.8 13.8 9e-07 28.9 13.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.21 ETS76545.1 - 2.4e-60 204.6 0.0 2.8e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ADH_N PF08240.12 ETS76546.1 - 8e-28 96.5 0.4 1.6e-27 95.5 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS76546.1 - 2.3e-21 76.1 0.0 3.5e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS76546.1 - 9.2e-08 31.8 0.3 1.2e-07 31.4 0.3 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 ETS76546.1 - 0.00033 20.9 0.1 0.00057 20.1 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 ETS76546.1 - 0.0013 18.2 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 ETS76546.1 - 0.0021 19.1 0.0 0.0035 18.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AIRS PF00586.24 ETS76546.1 - 0.0072 17.0 0.2 0.28 11.9 0.2 2.5 1 1 0 1 1 1 1 AIR synthase related protein, N-terminal domain NADH_4Fe-4S PF10589.9 ETS76546.1 - 0.019 15.0 3.1 0.045 13.8 3.1 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Shikimate_DH PF01488.20 ETS76546.1 - 0.022 14.8 0.0 0.034 14.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 ETS76546.1 - 0.038 14.4 0.4 0.069 13.6 0.4 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 ETS76546.1 - 0.065 13.5 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_3 PF13738.6 ETS76546.1 - 0.12 11.6 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 ETS76547.1 - 3.2e-21 75.7 34.6 1.4e-17 63.7 7.9 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS76547.1 - 0.008 14.8 0.9 0.008 14.8 0.9 2.8 2 2 0 2 2 2 2 MFS/sugar transport protein Methyltransf_24 PF13578.6 ETS76548.1 - 5.1e-11 43.5 0.0 8.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 ETS76548.1 - 4.1e-07 29.4 0.0 6.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase CmcI PF04989.12 ETS76548.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 2 1 0 2 2 2 0 Cephalosporin hydroxylase CorA PF01544.18 ETS76549.1 - 2.4e-07 30.3 0.3 6.7e-07 28.9 0.3 1.8 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein FA_desaturase PF00487.24 ETS76550.1 - 8.7e-28 97.8 24.8 1.4e-27 97.2 24.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 ETS76550.1 - 0.0048 17.1 0.0 0.0096 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Abhydrolase_3 PF07859.13 ETS76551.1 - 3e-19 69.7 0.1 4.3e-19 69.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS76551.1 - 2.6e-15 56.2 0.0 4e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF4990 PF16380.5 ETS76552.1 - 0.022 14.9 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function Abhydrolase_6 PF12697.7 ETS76553.1 - 1.1e-09 39.2 0.0 1.4e-09 38.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS76553.1 - 0.0021 17.4 0.0 2.2 7.5 0.0 2.9 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 ETS76553.1 - 0.12 12.1 0.0 0.45 10.3 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Haem_degrading PF03928.14 ETS76556.1 - 6.9e-20 71.3 0.1 8.5e-20 71.0 0.1 1.1 1 0 0 1 1 1 1 Haem-degrading AA_permease PF00324.21 ETS76557.1 - 6.1e-105 351.6 42.0 7.4e-105 351.3 42.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS76557.1 - 8.9e-23 80.8 43.1 1.2e-22 80.4 43.1 1.0 1 0 0 1 1 1 1 Amino acid permease OCD_Mu_crystall PF02423.15 ETS76558.1 - 1.2e-20 73.7 0.7 1.6e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 ETS76558.1 - 6e-08 32.8 0.0 0.00063 19.8 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 ETS76559.1 - 2.8e-28 99.5 0.2 3.2e-28 99.3 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS76559.1 - 0.0045 16.1 0.1 0.0077 15.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain F420_oxidored PF03807.17 ETS76559.1 - 0.02 15.5 0.0 0.053 14.1 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 ETS76559.1 - 0.02 14.8 0.2 0.04 13.8 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 ETS76559.1 - 0.034 13.8 4.5 0.12 12.1 0.5 2.8 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 ETS76559.1 - 0.036 13.3 0.0 0.07 12.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS76559.1 - 0.041 14.1 0.2 0.12 12.7 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ETS76559.1 - 0.069 13.7 0.9 0.24 12.0 0.4 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ETS76559.1 - 0.12 12.8 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 ETS76559.1 - 1.4 8.5 5.5 0.17 11.4 0.7 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_106 PF17132.4 ETS76560.1 - 3.9e-22 78.4 0.0 2.1e-21 75.9 0.0 2.0 2 1 0 2 2 2 1 alpha-L-rhamnosidase Aldedh PF00171.22 ETS76561.1 - 1.2e-107 360.3 0.2 1.5e-107 360.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.18 ETS76562.1 - 7e-17 61.3 0.1 1.1e-16 60.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Flavin_Reduct PF01613.18 ETS76563.1 - 2e-17 63.7 0.0 3.3e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 ETS76563.1 - 0.045 13.5 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Putative_PNPOx PF01243.20 ETS76563.1 - 0.093 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Pro_dh PF01619.18 ETS76564.1 - 2.7e-56 191.3 0.0 3e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Aminotran_1_2 PF00155.21 ETS76565.1 - 6e-55 186.9 0.0 2e-54 185.1 0.0 1.7 1 1 1 2 2 2 1 Aminotransferase class I and II MFS_1 PF07690.16 ETS76566.1 - 2.9e-40 138.3 25.0 2.9e-40 138.3 25.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1932 PF09130.11 ETS76567.1 - 3.9e-19 68.4 0.1 1.1e-18 67.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) IlvN PF07991.12 ETS76567.1 - 0.017 14.7 0.0 0.039 13.5 0.0 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 ETS76567.1 - 0.019 15.5 0.0 0.039 14.5 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ETS76567.1 - 0.029 13.8 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.18 ETS76568.1 - 1.3e-20 73.5 0.0 2.2e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS76568.1 - 6.9e-09 35.7 8.6 1.6e-08 34.5 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UVR PF02151.19 ETS76568.1 - 0.056 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 UvrB/uvrC motif Bac_luciferase PF00296.20 ETS76569.1 - 6.8e-53 180.1 0.7 2.5e-52 178.3 0.7 1.8 1 1 0 1 1 1 1 Luciferase-like monooxygenase ADH_zinc_N PF00107.26 ETS76570.1 - 8.1e-07 29.1 0.2 1.5e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS76570.1 - 1.5e-06 28.1 0.0 1.1e-05 25.2 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain TmoB PF06234.12 ETS76570.1 - 0.14 12.2 0.1 0.74 9.9 0.0 2.2 2 0 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) MFS_1 PF07690.16 ETS76571.1 - 1.4e-30 106.4 28.9 2e-30 105.9 28.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS76571.1 - 0.00024 20.5 2.8 0.00024 20.5 2.8 2.3 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Fungal_lectin_2 PF18647.1 ETS76572.1 - 0.029 14.8 0.1 0.042 14.3 0.1 1.2 1 0 0 1 1 1 0 Alpha-galactosyl-binding fungal lectin FAM53 PF15242.6 ETS76572.1 - 0.15 11.9 0.1 0.18 11.6 0.1 1.1 1 0 0 1 1 1 0 Family of FAM53 GIT1_C PF12205.8 ETS76573.1 - 0.081 13.0 0.4 0.99 9.5 0.2 2.5 2 1 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Extensin_2 PF04554.13 ETS76574.1 - 0.0021 18.1 19.0 0.0021 18.1 19.0 2.3 2 0 0 2 2 2 1 Extensin-like region PAN_1 PF00024.26 ETS76575.1 - 7.1e-13 48.3 14.8 0.00035 20.5 0.4 3.4 3 0 0 3 3 3 3 PAN domain PAN_4 PF14295.6 ETS76575.1 - 5.6e-09 35.8 11.5 6.9e-05 22.7 0.2 3.7 3 0 0 3 3 3 3 PAN domain PAN_3 PF08277.12 ETS76575.1 - 0.0001 22.1 7.1 0.045 13.5 0.1 3.4 3 0 0 3 3 3 3 PAN-like domain MANEC PF07502.14 ETS76575.1 - 0.00055 20.1 13.4 0.17 12.2 1.5 3.7 3 0 0 3 3 3 3 MANEC domain 2OG-FeII_Oxy_3 PF13640.6 ETS76577.1 - 5.7e-11 43.2 0.0 9.2e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 ETS76578.1 - 3.6e-28 95.4 27.2 0.0004 20.3 0.3 13.8 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_1 PF00515.28 ETS76578.1 - 1.5e-26 91.0 27.5 1.7e-05 24.4 0.2 13.7 15 0 0 15 15 15 6 Tetratricopeptide repeat TPR_8 PF13181.6 ETS76578.1 - 9.3e-23 78.5 24.9 0.0003 20.8 0.1 13.2 15 0 0 15 15 13 5 Tetratricopeptide repeat TPR_7 PF13176.6 ETS76578.1 - 6.4e-20 69.7 13.6 0.00011 22.0 0.1 9.2 9 0 0 9 9 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 ETS76578.1 - 2.3e-18 65.3 32.6 9.8e-05 22.9 0.0 14.1 14 2 2 16 16 15 5 Tetratricopeptide repeat TPR_12 PF13424.6 ETS76578.1 - 1.6e-16 60.3 19.2 3.7e-05 23.9 0.1 9.2 8 2 1 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 ETS76578.1 - 8.4e-16 58.2 32.8 0.0046 17.4 0.3 12.2 9 5 2 11 11 11 4 Tetratricopeptide repeat TPR_6 PF13174.6 ETS76578.1 - 5e-15 55.0 17.3 4.1e-05 23.9 0.0 10.2 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 ETS76578.1 - 2.6e-14 53.6 22.0 0.00018 22.0 0.1 9.3 12 0 0 12 12 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 ETS76578.1 - 5.1e-13 48.5 24.5 0.041 13.6 0.0 9.8 9 1 1 10 10 10 4 TPR repeat TPR_17 PF13431.6 ETS76578.1 - 5.7e-10 38.9 17.1 0.21 12.0 0.0 12.0 14 0 0 14 14 13 1 Tetratricopeptide repeat TPR_10 PF13374.6 ETS76578.1 - 8.5e-08 31.8 18.8 0.23 11.4 0.0 8.6 10 0 0 10 10 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS76578.1 - 0.0024 18.1 11.5 7.9 6.8 0.1 6.4 7 1 0 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 ETS76578.1 - 0.0057 16.8 0.7 5.8 7.4 0.0 4.6 4 0 0 4 4 2 1 PPR repeat TPR_9 PF13371.6 ETS76578.1 - 0.33 11.1 7.7 1.9 8.7 0.0 5.4 7 0 0 7 7 6 0 Tetratricopeptide repeat Cellulase PF00150.18 ETS76579.1 - 1.2e-44 152.9 0.0 1.7e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Rhomboid PF01694.22 ETS76580.1 - 6.2e-17 62.0 13.0 1.2e-16 61.1 13.0 1.3 1 0 0 1 1 1 1 Rhomboid family EHN PF06441.12 ETS76581.1 - 2e-27 95.7 0.1 9.4e-27 93.5 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ETS76581.1 - 1.7e-14 54.1 0.0 2.8e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS76581.1 - 0.00013 22.6 0.6 0.00025 21.7 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.22 ETS76582.1 - 7.2e-40 137.1 0.0 9.3e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SOG2 PF10428.9 ETS76582.1 - 0.21 10.7 0.0 17 4.5 0.0 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein DUF4383 PF14325.6 ETS76583.1 - 0.07 13.4 7.1 0.036 14.3 3.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4383) MerC PF03203.14 ETS76583.1 - 2.6 8.5 15.9 1 9.8 1.1 3.1 1 1 1 3 3 3 0 MerC mercury resistance protein Methyltransf_25 PF13649.6 ETS76584.1 - 6.1e-09 36.5 0.0 5.5e-08 33.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS76584.1 - 3.5e-07 30.2 0.0 5.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS76584.1 - 1.5e-05 25.6 0.0 2.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS76584.1 - 3e-05 23.9 0.0 0.00027 20.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS76584.1 - 9.6e-05 23.0 0.0 0.00025 21.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS76584.1 - 0.11 11.8 0.0 1.4 8.2 0.0 2.4 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Prenyltrans PF00432.21 ETS76585.1 - 0.0061 16.3 0.1 5.9 6.7 0.0 2.8 2 0 0 2 2 2 2 Prenyltransferase and squalene oxidase repeat GST_N PF02798.20 ETS76586.1 - 1.6e-14 54.0 0.0 1.9e-13 50.5 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ETS76586.1 - 1.4e-13 50.9 0.0 2.7e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ETS76586.1 - 2.9e-11 43.6 0.0 5.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS76586.1 - 2.4e-09 37.1 0.3 4.6e-09 36.2 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ETS76586.1 - 2.5e-09 37.2 0.0 4.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ETS76586.1 - 8e-09 35.7 0.0 1.9e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 ETS76586.1 - 0.049 14.2 0.1 0.55 10.8 0.0 2.4 2 1 1 3 3 3 0 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 ETS76587.1 - 4.6e-39 134.3 55.7 7e-38 130.4 53.8 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 ETS76588.1 - 3.2e-25 88.8 0.0 3.9e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS76590.1 - 2e-28 99.4 0.0 2.5e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3623 PF12291.8 ETS76591.1 - 0.11 11.6 0.2 0.19 10.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) MFS_1 PF07690.16 ETS76594.1 - 4.5e-25 88.3 31.4 1e-20 74.0 6.1 3.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS76594.1 - 5.8e-11 41.9 7.6 5.8e-11 41.9 7.6 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter Tetraspanin PF00335.20 ETS76594.1 - 1.1 9.0 0.0 1.1 9.0 0.0 3.1 3 1 0 3 3 3 0 Tetraspanin family p450 PF00067.22 ETS76595.1 - 9.3e-48 163.1 0.0 1.3e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3392 PF11872.8 ETS76596.1 - 0.4 11.0 5.5 11 6.3 0.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3392) ketoacyl-synt PF00109.26 ETS76597.1 - 2.5e-61 207.5 0.0 4.3e-61 206.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ETS76597.1 - 4.3e-50 170.1 0.2 9.7e-50 169.0 0.2 1.7 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 ETS76597.1 - 4.4e-50 171.0 0.0 1.9e-49 168.9 0.0 2.1 3 0 0 3 3 3 1 Acyl transferase domain PS-DH PF14765.6 ETS76597.1 - 9.8e-45 153.1 0.0 1.7e-44 152.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 ETS76597.1 - 6.9e-36 122.8 0.0 1.6e-35 121.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ETS76597.1 - 7.1e-19 68.4 0.0 3e-18 66.4 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ETS76597.1 - 3.7e-17 62.8 0.0 1.7e-16 60.7 0.0 2.1 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 ETS76597.1 - 1.1e-15 58.9 0.0 8.6e-15 56.0 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 ETS76597.1 - 4.4e-13 49.4 0.0 8.9e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 ETS76597.1 - 5.9e-13 48.9 0.4 3e-12 46.6 0.1 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ETS76597.1 - 6.8e-10 38.7 0.0 1.6e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_25 PF13649.6 ETS76597.1 - 1.3e-09 38.7 0.0 6.2e-09 36.4 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS76597.1 - 3.7e-09 37.1 0.0 1.1e-08 35.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 ETS76597.1 - 5.7e-09 36.2 0.0 1.6e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 ETS76597.1 - 5.6e-08 32.7 0.0 1.4e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS76597.1 - 8.1e-06 25.3 0.0 2.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.10 ETS76597.1 - 0.00061 19.6 0.1 0.0017 18.2 0.1 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 ETS76597.1 - 0.00085 18.7 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_33 PF10017.9 ETS76597.1 - 0.00095 18.4 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent adh_short_C2 PF13561.6 ETS76597.1 - 0.0023 17.5 0.1 0.033 13.7 0.0 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase SAT PF16073.5 ETS76597.1 - 0.013 15.2 0.1 0.03 14.0 0.1 1.5 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_28 PF02636.17 ETS76597.1 - 0.031 13.9 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ADH_N PF08240.12 ETS76597.1 - 0.08 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Glyco_hydro_49N PF17433.2 ETS76599.1 - 1.6e-55 187.7 5.0 4.9e-55 186.1 5.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 49 N-terminal Ig-like domain IPU_b_solenoid PF18783.1 ETS76599.1 - 8.4e-18 64.1 3.1 8.4e-18 64.1 3.1 2.0 2 0 0 2 2 2 1 Isopullulanase beta-solenoid repeat B_solenoid_dext PF18841.1 ETS76599.1 - 4.4e-17 62.1 1.6 1.8e-16 60.1 1.6 2.2 1 0 0 1 1 1 1 Beta solenoid repeat from Dextranase Glyco_hydro_49 PF03718.13 ETS76599.1 - 1.6e-16 60.4 4.1 2.4e-16 59.8 0.7 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 49 Ank_2 PF12796.7 ETS76601.1 - 1.1e-59 199.0 24.4 5.8e-13 49.2 2.1 5.1 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS76601.1 - 2.7e-30 101.0 7.1 0.0015 18.8 0.0 9.6 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 ETS76601.1 - 7.8e-28 96.5 5.2 1.4e-06 28.7 0.0 6.5 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS76601.1 - 5.4e-24 83.9 10.8 6.1e-06 26.4 0.1 8.4 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 ETS76601.1 - 1.4e-17 63.2 18.9 0.085 13.3 0.1 9.2 9 0 0 9 9 9 5 Ankyrin repeat DUF2384 PF09722.10 ETS76601.1 - 0.00043 20.3 0.6 21 5.2 0.0 6.0 6 1 1 7 7 7 1 Protein of unknown function (DUF2384) PBP PF01161.20 ETS76602.1 - 3.1e-09 37.3 0.0 4.7e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Zn_clus PF00172.18 ETS76603.1 - 0.00016 21.8 10.6 0.00026 21.1 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.18 ETS76604.1 - 0.0013 18.1 3.8 0.0058 16.0 0.0 3.2 3 1 1 4 4 4 1 CorA-like Mg2+ transporter protein Pkinase PF00069.25 ETS76605.1 - 6.3e-15 55.3 0.0 1.2e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS76605.1 - 1.1e-07 31.4 0.0 1.1e-06 28.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase GMC_oxred_C PF05199.13 ETS76606.1 - 1.7e-22 80.5 0.1 1.8e-22 80.4 0.1 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Lactonase PF10282.9 ETS76607.1 - 9.1e-85 284.9 0.1 1.2e-84 284.5 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Clr5 PF14420.6 ETS76610.1 - 1.7e-16 60.1 1.9 1.8e-16 60.1 0.1 2.1 2 0 0 2 2 2 1 Clr5 domain Ank_2 PF12796.7 ETS76610.1 - 1.2e-11 45.0 0.0 0.0035 17.9 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 ETS76610.1 - 4.5e-09 36.4 0.3 0.0078 16.6 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 ETS76610.1 - 3.4e-07 30.0 0.0 1.1 10.0 0.0 5.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 ETS76610.1 - 3.6e-07 30.6 0.0 0.41 11.3 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS76610.1 - 0.002 18.4 0.2 2 8.9 0.0 3.9 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Chromo PF00385.24 ETS76611.1 - 0.0097 15.8 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain FAM25 PF15825.5 ETS76612.1 - 0.0051 17.1 0.6 0.057 13.8 0.1 2.6 3 0 0 3 3 3 1 FAM25 family DUF1129 PF06570.11 ETS76613.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DJ-1_PfpI PF01965.24 ETS76614.1 - 4.3e-08 33.1 0.0 8.8e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family Fungal_trans PF04082.18 ETS76615.1 - 3.7e-20 72.1 0.5 9.2e-20 70.8 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS76615.1 - 2.7e-08 33.8 11.1 4.4e-08 33.1 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC92 PF14916.6 ETS76615.1 - 0.0075 16.0 1.1 0.014 15.2 0.2 1.8 2 0 0 2 2 2 1 Coiled-coil domain of unknown function DUF2457 PF10446.9 ETS76615.1 - 0.035 13.2 4.1 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF4094 PF13334.6 ETS76615.1 - 0.068 13.6 0.1 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) T3SS_LEE_assoc PF13327.6 ETS76615.1 - 0.087 12.8 0.0 9.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Type III secretion system subunit IFP_35_N PF07334.13 ETS76615.1 - 0.22 11.6 0.3 0.77 9.9 0.3 1.9 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Cep57_CLD_2 PF14197.6 ETS76615.1 - 0.23 11.6 1.6 0.47 10.6 1.1 1.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 ETS76615.1 - 1.3 8.8 2.8 2 8.3 1.1 2.0 2 0 0 2 2 2 0 Septum formation initiator FAD_binding_3 PF01494.19 ETS76616.1 - 8.2e-30 104.2 0.0 1.2e-29 103.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ETS76616.1 - 2.4e-06 26.9 0.7 0.03 13.4 0.0 2.7 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 ETS76616.1 - 2.9e-05 24.2 0.3 0.00012 22.3 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS76616.1 - 4.4e-05 22.9 0.1 0.0021 17.4 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS76616.1 - 0.0099 15.1 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ETS76616.1 - 0.014 14.8 0.1 3.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 ETS76616.1 - 0.029 13.6 0.6 0.051 12.8 0.1 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 ETS76616.1 - 0.034 14.7 0.2 0.23 12.0 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS76616.1 - 0.1 12.2 2.2 0.095 12.3 0.5 1.8 2 1 0 2 2 2 0 FAD dependent oxidoreductase Cu-oxidase_3 PF07732.15 ETS76617.1 - 8.9e-44 148.3 1.3 8.9e-44 148.3 1.3 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ETS76617.1 - 2.9e-43 146.9 10.4 1.3e-40 138.3 0.5 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 ETS76617.1 - 2.7e-33 115.4 0.4 6.7e-33 114.1 0.4 1.7 1 0 0 1 1 1 1 Multicopper oxidase COesterase PF00135.28 ETS76618.1 - 7.2e-56 190.1 0.0 2.3e-49 168.7 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS76618.1 - 1.2e-06 28.5 0.0 2.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold ABM PF03992.16 ETS76619.1 - 4.2e-05 23.6 0.1 7.1e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Aldo_ket_red PF00248.21 ETS76620.1 - 2.4e-67 227.2 0.0 3.1e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Glycos_trans_3N PF02885.17 ETS76620.1 - 0.06 13.2 0.0 4.2 7.3 0.0 2.7 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain GFO_IDH_MocA PF01408.22 ETS76621.1 - 1.2e-14 55.2 0.0 2e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AAA PF00004.29 ETS76622.1 - 3.3e-16 59.9 0.0 5.8e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ETS76622.1 - 0.067 13.6 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 ETS76622.1 - 0.15 12.3 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran_CTD PF16326.5 ETS76623.1 - 0.0052 17.0 1.0 0.0052 17.0 1.0 4.0 4 1 0 4 4 4 1 ABC transporter C-terminal domain BST2 PF16716.5 ETS76623.1 - 0.022 15.3 7.7 0.022 15.3 7.7 4.0 4 1 0 4 4 4 0 Bone marrow stromal antigen 2 DUF948 PF06103.11 ETS76623.1 - 0.029 14.6 16.1 1.3 9.3 0.6 4.5 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 ETS76623.1 - 0.045 13.8 16.7 0.29 11.2 1.8 4.3 2 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ZapB PF06005.12 ETS76623.1 - 0.075 13.5 0.4 0.075 13.5 0.4 4.4 3 1 1 4 4 3 0 Cell division protein ZapB ATG16 PF08614.11 ETS76623.1 - 0.093 13.0 27.8 0.23 11.7 5.1 2.9 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) FH2 PF02181.23 ETS76623.1 - 0.23 10.5 15.3 0.48 9.5 5.3 3.2 1 1 3 4 4 4 0 Formin Homology 2 Domain SKA1 PF07160.12 ETS76623.1 - 0.56 10.0 20.7 0.1 12.4 7.7 2.8 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 APG17 PF04108.12 ETS76623.1 - 0.68 9.0 26.1 1.9 7.5 7.0 3.3 1 1 2 3 3 3 0 Autophagy protein Apg17 Bacillus_HBL PF05791.11 ETS76623.1 - 1.1 9.0 9.8 0.64 9.8 3.1 3.0 2 2 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) HisKA_3 PF07730.13 ETS76623.1 - 1.6 9.3 14.6 9.7 6.8 0.2 4.6 5 1 0 5 5 4 0 Histidine kinase Fib_alpha PF08702.10 ETS76623.1 - 2.5 8.3 25.6 4.2 7.6 2.8 4.2 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Vac_Fusion PF02346.16 ETS76623.1 - 2.6 7.7 13.3 0.062 12.9 2.6 3.7 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 DUF4407 PF14362.6 ETS76623.1 - 2.6 7.3 11.7 0.92 8.8 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ntox28 PF15605.6 ETS76623.1 - 2.7 8.3 6.9 0.35 11.1 0.3 2.7 2 1 1 3 3 3 0 Bacterial toxin 28 ApoO PF09769.9 ETS76623.1 - 2.9 7.9 13.9 4.7 7.2 1.4 3.9 3 1 1 4 4 4 0 Apolipoprotein O DUF1664 PF07889.12 ETS76623.1 - 3.3 7.8 26.5 1.2 9.2 1.5 5.1 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) DUF1319 PF07028.11 ETS76623.1 - 3.3 8.0 12.1 3 8.1 4.7 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1319) FlaC_arch PF05377.11 ETS76623.1 - 4 7.9 22.5 12 6.3 1.2 6.3 4 2 2 7 7 7 0 Flagella accessory protein C (FlaC) DUF4061 PF13270.6 ETS76623.1 - 5.1 7.5 16.3 0.62 10.4 1.9 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4061) DUF2508 PF10704.9 ETS76623.1 - 6.1 7.1 9.1 9.4 6.5 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) DUF3584 PF12128.8 ETS76623.1 - 7.4 3.9 33.0 1.3 6.4 17.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) MscS_porin PF12795.7 ETS76623.1 - 9.3 5.7 29.5 3.8 7.0 3.0 3.2 3 1 0 3 3 3 0 Mechanosensitive ion channel porin domain ERG4_ERG24 PF01222.17 ETS76624.1 - 2e-168 560.6 1.5 2.2e-168 560.5 1.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 ETS76624.1 - 0.00023 20.8 0.0 0.00056 19.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Man-6-P_recep PF02157.15 ETS76625.1 - 4.4e-13 48.9 0.0 9.7e-13 47.8 0.0 1.5 2 0 0 2 2 2 1 Mannose-6-phosphate receptor ATG27 PF09451.10 ETS76625.1 - 1e-12 48.5 0.0 2.1e-12 47.5 0.0 1.7 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 ETS76625.1 - 1.5e-05 25.1 0.6 0.0023 18.0 0.0 2.5 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PBP1_TM PF14812.6 ETS76625.1 - 2.5 8.5 6.0 9.9 6.6 0.3 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PNGaseA PF12222.8 ETS76626.1 - 5.5e-142 473.7 1.8 7e-142 473.3 1.8 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A NmrA PF05368.13 ETS76627.1 - 1.3e-20 73.9 0.0 1.7e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS76627.1 - 1.6e-12 47.7 0.0 4.9e-12 46.1 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding DUF3394 PF11874.8 ETS76627.1 - 0.0038 16.9 0.0 0.0074 16.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3394) Transferase PF02458.15 ETS76628.1 - 2.6e-08 33.0 0.0 6.5e-08 31.6 0.0 1.5 1 1 0 1 1 1 1 Transferase family BRI3BP PF14965.6 ETS76629.1 - 0.0098 15.4 2.6 0.19 11.2 0.3 2.1 1 1 1 2 2 2 1 Negative regulator of p53/TP53 Tektin PF03148.14 ETS76629.1 - 0.012 14.4 11.2 0.013 14.3 11.2 1.2 1 1 0 1 1 1 0 Tektin family Histone_HNS PF00816.21 ETS76629.1 - 0.015 16.1 2.7 0.015 16.1 2.7 2.7 1 1 2 3 3 3 0 H-NS histone family Metal_resist PF13801.6 ETS76629.1 - 0.027 14.6 4.8 0.046 13.9 4.8 1.3 1 0 0 1 1 1 0 Heavy-metal resistance Baculo_PEP_C PF04513.12 ETS76629.1 - 0.039 14.0 0.3 0.066 13.2 0.3 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran_CTD PF16326.5 ETS76629.1 - 0.042 14.1 8.7 1 9.7 0.8 2.4 1 1 1 2 2 2 0 ABC transporter C-terminal domain Lzipper-MIP1 PF14389.6 ETS76629.1 - 0.066 13.5 4.6 2 8.8 4.6 2.4 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Fzo_mitofusin PF04799.13 ETS76629.1 - 0.2 11.2 5.3 0.055 13.0 2.3 1.6 2 0 0 2 2 2 0 fzo-like conserved region DUF3287 PF11690.8 ETS76629.1 - 0.73 9.6 8.9 0.17 11.6 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Spore_III_AF PF09581.10 ETS76629.1 - 1.7 8.6 9.0 0.11 12.5 1.8 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Remorin_C PF03763.13 ETS76629.1 - 2.1 8.2 14.9 0.55 10.1 11.8 1.5 2 0 0 2 2 2 0 Remorin, C-terminal region TMPIT PF07851.13 ETS76629.1 - 4.4 6.5 5.0 6.1 6.0 5.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein SlyX PF04102.12 ETS76629.1 - 4.5 8.0 10.6 1.9 9.2 6.0 2.4 1 1 1 2 2 2 0 SlyX Allexi_40kDa PF05549.11 ETS76629.1 - 4.8 6.6 8.4 0.47 9.9 3.1 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein SOBP PF15279.6 ETS76629.1 - 5.7 7.5 11.2 6.8 7.2 11.2 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein CRAL_TRIO PF00650.20 ETS76630.1 - 3.4e-10 39.9 0.0 5.3e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ETS76630.1 - 0.00061 19.9 0.0 0.0016 18.6 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain PLDc_N PF13396.6 ETS76632.1 - 1.7e-13 50.2 2.8 3.7e-13 49.2 2.8 1.6 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal PTS_EIIC_2 PF13303.6 ETS76632.1 - 0.012 14.7 1.1 0.014 14.5 1.1 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC Pox_A14 PF05767.12 ETS76632.1 - 0.075 13.2 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF1673 PF07895.11 ETS76632.1 - 0.21 11.3 1.5 0.29 10.8 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF3951 PF13131.6 ETS76632.1 - 0.31 11.3 0.0 0.31 11.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3951) DUF2207 PF09972.9 ETS76632.1 - 1.7 7.3 3.2 1.8 7.3 3.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Amidase PF01425.21 ETS76633.1 - 8.1e-87 292.0 0.0 1.4e-86 291.2 0.0 1.3 1 1 0 1 1 1 1 Amidase Glyco_transf_4 PF13439.6 ETS76633.1 - 0.0089 16.0 0.0 0.74 9.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase Family 4 ELH PF02323.15 ETS76633.1 - 0.18 11.1 0.1 0.3 10.4 0.1 1.2 1 0 0 1 1 1 0 Egg-laying hormone precursor HET PF06985.11 ETS76634.1 - 1.2e-30 106.8 0.4 2.5e-30 105.7 0.4 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 ETS76635.1 - 8.9e-06 26.2 0.1 0.00039 20.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS76635.1 - 5.1e-05 23.5 0.4 0.0007 19.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS76635.1 - 0.0026 18.3 0.3 0.042 14.5 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS76635.1 - 0.02 15.4 1.1 6.1 7.8 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeat Styelin PF17562.2 ETS76635.1 - 0.08 13.3 0.6 0.24 11.8 0.1 2.1 1 1 1 2 2 2 0 Styelin p450 PF00067.22 ETS76636.1 - 2.1e-59 201.5 0.0 2.8e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Melibiase_2 PF16499.5 ETS76637.1 - 1.2e-47 162.5 2.3 2e-47 161.7 1.2 2.0 2 0 0 2 2 2 1 Alpha galactosidase A Melibiase_C PF17801.1 ETS76637.1 - 3.1e-09 36.8 1.4 1.2e-08 34.9 0.0 2.6 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 ETS76637.1 - 0.023 13.6 0.1 0.055 12.4 0.0 1.5 2 0 0 2 2 2 0 Melibiase Alginate_lyase PF05426.12 ETS76638.1 - 0.0086 15.7 9.4 0.024 14.2 9.3 1.7 1 1 0 1 1 1 1 Alginate lyase Ammonium_transp PF00909.21 ETS76639.1 - 7.5e-112 373.9 20.9 9.3e-112 373.6 20.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Epimerase PF01370.21 ETS76641.1 - 5.4e-15 55.5 0.0 7.9e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ETS76641.1 - 5.5e-08 32.7 0.0 8e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 ETS76641.1 - 1.4e-07 30.8 0.0 2.1e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ETS76641.1 - 1.9e-07 31.2 0.0 3.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 ETS76641.1 - 2.7e-05 23.7 0.0 4.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 ETS76641.1 - 0.0074 15.7 0.0 0.022 14.2 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ETS76641.1 - 0.053 12.6 0.0 0.71 8.9 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.20 ETS76641.1 - 0.19 11.9 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HET PF06985.11 ETS76643.1 - 1.3e-24 87.2 0.0 2.5e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Epimerase PF01370.21 ETS76644.1 - 4.2e-18 65.7 0.0 5.8e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS76644.1 - 3.3e-12 46.5 0.0 4.3e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ETS76644.1 - 1.1e-10 41.0 0.0 1.4e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ETS76644.1 - 7e-09 35.2 0.0 1.8e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ETS76644.1 - 9.7e-06 24.9 0.0 0.0071 15.5 0.0 2.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 ETS76644.1 - 6.8e-05 22.8 0.0 9.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 ETS76644.1 - 0.001 19.0 0.0 0.0086 16.0 0.0 2.0 1 1 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 ETS76644.1 - 0.02 15.0 0.0 0.028 14.5 0.0 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 ETS76644.1 - 0.031 13.7 0.0 0.11 11.9 0.0 2.0 1 1 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.15 ETS76644.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.18 ETS76645.1 - 3.2e-25 88.7 0.4 6.1e-25 87.7 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS76645.1 - 4.1e-08 33.2 8.8 9.1e-08 32.1 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ILVD_EDD PF00920.21 ETS76646.1 - 1.7e-50 172.1 0.0 1.9e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family RVT_thumb PF06817.14 ETS76647.1 - 0.017 15.0 0.3 0.036 13.9 0.3 1.6 1 0 0 1 1 1 0 Reverse transcriptase thumb domain AA_permease_2 PF13520.6 ETS76648.1 - 6.2e-44 150.5 45.3 7.7e-44 150.2 45.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS76648.1 - 1.1e-13 50.6 39.0 1.5e-13 50.2 39.0 1.1 1 0 0 1 1 1 1 Amino acid permease Phtf-FEM1B_bdg PF12129.8 ETS76648.1 - 6 6.7 8.3 0.83 9.5 0.3 2.7 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor Amino_oxidase PF01593.24 ETS76649.1 - 1e-56 193.1 0.2 1.2e-56 192.9 0.2 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ETS76649.1 - 8.1e-12 45.2 0.2 1.7e-11 44.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS76649.1 - 8.3e-07 28.9 0.1 3.5e-05 23.5 0.0 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 ETS76649.1 - 4.1e-06 26.2 0.0 6.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 ETS76649.1 - 5.9e-05 22.6 0.1 0.00011 21.8 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS76649.1 - 0.0001 21.6 0.0 0.00041 19.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS76649.1 - 0.00021 20.5 0.2 0.00033 19.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 ETS76649.1 - 0.0028 16.8 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 ETS76649.1 - 0.0077 15.0 0.0 0.014 14.1 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 ETS76649.1 - 0.0088 15.3 0.2 0.41 9.9 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS76649.1 - 0.015 14.6 0.1 1.8 7.7 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 ETS76649.1 - 0.095 11.7 0.1 0.21 10.6 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Fungal_trans_2 PF11951.8 ETS76650.1 - 9.5e-21 74.0 0.1 2.9e-11 42.8 0.0 2.1 1 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS76650.1 - 9.4e-06 25.7 8.9 1.7e-05 24.8 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain S1-P1_nuclease PF02265.16 ETS76651.1 - 9.6e-54 182.9 0.0 1.1e-53 182.6 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease Prok-RING_1 PF14446.6 ETS76651.1 - 0.052 13.5 0.8 0.14 12.1 0.2 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 G-alpha PF00503.20 ETS76652.1 - 3.6e-28 98.7 0.4 8.3e-28 97.6 0.4 1.6 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ETS76652.1 - 4.5e-06 26.2 0.5 1.2e-05 24.8 0.1 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ETS76652.1 - 0.0041 17.2 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Sugar_tr PF00083.24 ETS76653.1 - 7.8e-59 199.7 28.1 9.7e-59 199.4 28.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS76653.1 - 1.1e-21 77.2 35.7 1.7e-21 76.6 35.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Bacteriocin_IIc PF10439.9 ETS76653.1 - 1.2 9.3 6.6 0.55 10.4 3.5 2.1 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Glyco_hyd_65N_2 PF14498.6 ETS76654.1 - 2.2e-58 197.9 0.0 2.8e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Phage_TTP_12 PF16461.5 ETS76654.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Lambda phage tail tube protein, TTP NUDE_C PF04880.13 ETS76655.1 - 3.8e-38 131.7 24.0 3.8e-38 131.7 24.0 4.5 2 1 3 5 5 5 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 ETS76655.1 - 0.0035 17.7 11.2 0.0035 17.7 11.2 4.5 2 1 3 5 5 5 2 Cell division protein ZapB ERM PF00769.19 ETS76655.1 - 0.093 12.5 35.4 0.13 12.1 14.1 2.1 2 1 1 3 3 3 0 Ezrin/radixin/moesin family Chibby PF14645.6 ETS76655.1 - 0.38 11.2 12.8 2.9 8.3 3.1 2.6 1 1 1 2 2 2 0 Chibby family Filament PF00038.21 ETS76655.1 - 0.71 9.4 30.7 0.88 9.1 12.2 2.9 2 1 1 3 3 3 0 Intermediate filament protein PRKG1_interact PF15898.5 ETS76655.1 - 1.6 9.7 28.7 0.091 13.7 11.8 3.4 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Fez1 PF06818.15 ETS76655.1 - 3.1 8.2 29.5 0.42 11.0 13.6 3.0 2 1 1 3 3 3 0 Fez1 NAD_binding_2 PF03446.15 ETS76657.1 - 2.8e-27 95.8 0.5 3.9e-27 95.3 0.5 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ETS76657.1 - 3.3e-07 30.6 0.1 8.7e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 ETS76657.1 - 1.4e-06 28.4 0.0 0.00011 22.3 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 ETS76657.1 - 8.5e-06 26.3 0.4 5.5e-05 23.7 0.1 2.4 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 ETS76657.1 - 0.049 13.9 0.0 0.2 11.9 0.0 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain LytR_C PF13399.6 ETS76657.1 - 0.078 14.0 0.0 2.4 9.2 0.0 3.1 2 1 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator CBM_21 PF03370.13 ETS76658.1 - 2e-32 111.7 0.3 3.7e-32 110.8 0.3 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 ETS76658.1 - 2.5e-11 44.0 0.7 4.9e-11 43.1 0.7 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Abhydrolase_6 PF12697.7 ETS76659.1 - 9.4e-15 55.8 0.0 1.1e-14 55.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS76659.1 - 0.003 16.9 0.1 2 7.6 0.0 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS76659.1 - 0.12 12.0 0.0 0.82 9.3 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold ACC_central PF08326.12 ETS76661.1 - 4.4e-270 898.0 0.0 5.7e-270 897.6 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 ETS76661.1 - 3.5e-184 613.0 0.0 4.9e-184 612.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 ETS76661.1 - 2.9e-51 174.0 0.0 5.4e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ETS76661.1 - 7.6e-28 97.3 0.1 1.6e-27 96.2 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ETS76661.1 - 5.2e-23 81.2 0.0 8.2e-21 74.1 0.0 2.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ETS76661.1 - 1.9e-18 66.0 0.4 6.3e-18 64.4 0.4 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme GxGYxYP_N PF16216.5 ETS76661.1 - 0.0028 17.9 0.0 0.0069 16.6 0.0 1.6 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal Biotin_lipoyl_2 PF13533.6 ETS76661.1 - 0.011 15.6 0.1 0.04 13.8 0.0 1.9 2 0 0 2 2 2 0 Biotin-lipoyl like ATP-grasp_3 PF02655.14 ETS76661.1 - 0.033 14.2 0.0 0.17 12.0 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ETS76661.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus BolA PF01722.18 ETS76662.1 - 1.1e-10 41.7 0.0 3.8e-10 39.9 0.0 1.9 2 1 0 2 2 2 1 BolA-like protein DUF3825 PF12873.7 ETS76662.1 - 0.033 13.6 0.0 0.042 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) FAD-oxidase_C PF02913.19 ETS76664.1 - 2.6e-53 181.2 0.0 3.5e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ETS76664.1 - 7.8e-39 132.6 0.0 1.4e-38 131.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain adh_short_C2 PF13561.6 ETS76665.1 - 3e-38 131.7 0.1 6.2e-37 127.4 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS76665.1 - 5.9e-36 123.8 0.4 9.5e-36 123.1 0.4 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS76665.1 - 5.5e-08 32.9 0.5 4.6e-07 29.9 0.2 2.1 1 1 1 2 2 2 1 KR domain DUF1776 PF08643.10 ETS76665.1 - 0.047 13.0 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Peptidase_S8 PF00082.22 ETS76666.1 - 2.4e-43 148.5 5.5 4e-42 144.5 5.5 2.1 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 ETS76666.1 - 1.8e-18 67.3 0.4 4.5e-18 66.0 0.4 1.8 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 ETS76666.1 - 5.3e-06 26.4 1.0 1.6e-05 24.8 0.2 2.3 2 0 0 2 2 2 1 PA domain FlgD_ig PF13860.6 ETS76666.1 - 4.6e-05 23.2 0.5 0.00048 19.9 0.1 2.7 2 0 0 2 2 2 1 FlgD Ig-like domain Inhibitor_I9 PF05922.16 ETS76666.1 - 0.027 15.1 0.0 0.15 12.8 0.0 2.1 1 1 0 1 1 1 0 Peptidase inhibitor I9 SLAC1 PF03595.17 ETS76667.1 - 1.4e-84 284.2 39.2 1.6e-84 284.0 39.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel PH_13 PF16652.5 ETS76667.1 - 0.14 11.9 0.1 0.22 11.3 0.1 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain VIT1 PF01988.19 ETS76669.1 - 9.5e-61 205.4 0.2 1.1e-60 205.2 0.2 1.0 1 0 0 1 1 1 1 VIT family hNIFK_binding PF12196.8 ETS76669.1 - 0.22 11.1 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Phosphoesterase PF04185.14 ETS76670.1 - 6.2e-33 114.4 2.7 3.3e-32 112.0 2.6 2.0 1 1 0 1 1 1 1 Phosphoesterase family His_Phos_1 PF00300.22 ETS76672.1 - 0.041 13.6 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Pox_A_type_inc PF04508.12 ETS76675.1 - 5.3 7.1 10.6 7.9 6.5 0.0 5.6 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Spc7 PF08317.11 ETS76675.1 - 8.8 5.1 106.5 0.032 13.1 12.7 7.7 3 2 4 7 7 7 0 Spc7 kinetochore protein POT1 PF02765.17 ETS76676.1 - 1.6e-16 60.4 0.0 4.1e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Ribosomal_L34 PF00468.17 ETS76677.1 - 8.9e-11 41.6 13.6 1.6e-10 40.8 13.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 Ish1 PF10281.9 ETS76678.1 - 3.3e-06 27.3 0.1 4.5e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein SAP PF02037.27 ETS76678.1 - 0.098 12.4 0.0 0.22 11.3 0.0 1.6 1 1 0 1 1 1 0 SAP domain tRNA-synt_1g PF09334.11 ETS76679.1 - 2.3e-89 299.9 0.6 2.2e-88 296.7 0.6 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ETS76679.1 - 5.9e-17 61.2 3.4 5.9e-11 41.3 0.1 4.1 1 1 2 4 4 4 4 tRNA synthetases class I (I, L, M and V) Acetyltransf_3 PF13302.7 ETS76679.1 - 7.8e-13 49.3 0.0 2.8e-12 47.5 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain tRNA-synt_1e PF01406.19 ETS76679.1 - 0.00012 21.6 0.1 0.0057 16.0 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 ETS76679.1 - 0.00012 22.0 0.0 0.00036 20.5 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA FR47 PF08445.10 ETS76679.1 - 0.025 14.5 0.0 0.67 10.0 0.0 2.5 2 0 0 2 2 2 0 FR47-like protein CorA PF01544.18 ETS76680.1 - 1e-10 41.4 0.0 2.7e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein GHMP_kinases_N PF00288.26 ETS76681.1 - 7.4e-16 58.1 0.1 1.8e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ETS76681.1 - 1.2e-07 32.0 0.0 2.9e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 ETS76681.1 - 0.031 13.8 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature PPTA PF01239.22 ETS76682.1 - 2.4e-38 128.7 11.3 4.5e-07 29.4 0.1 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat SNF2_N PF00176.23 ETS76683.1 - 9.2e-51 172.6 0.5 4.3e-46 157.2 0.0 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS76683.1 - 6.5e-16 58.6 0.0 4.3e-15 56.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS76683.1 - 2.5e-07 30.9 0.6 7.8e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 ETS76683.1 - 5.7e-06 26.1 13.7 5.7e-06 26.1 13.7 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS76683.1 - 0.00016 21.4 12.0 0.00016 21.4 12.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ETS76683.1 - 0.00037 20.8 13.4 0.00037 20.8 13.4 2.6 2 0 0 2 2 2 1 Ring finger domain AAA_34 PF13872.6 ETS76683.1 - 0.0034 16.3 0.0 0.0099 14.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-C3HC4_2 PF13923.6 ETS76683.1 - 0.0047 16.7 13.1 0.0047 16.7 13.1 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) UCH_1 PF13423.6 ETS76683.1 - 0.072 12.7 0.0 0.072 12.7 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase AT_hook PF02178.19 ETS76683.1 - 0.18 11.7 1.6 0.65 10.1 1.6 2.0 1 0 0 1 1 1 0 AT hook motif zf-Nse PF11789.8 ETS76683.1 - 6.4 6.7 9.2 1.8 8.4 5.7 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit LRR_6 PF13516.6 ETS76684.1 - 7.2e-05 22.5 0.9 0.012 15.6 0.0 5.0 7 0 0 7 7 6 1 Leucine Rich repeat LRR_8 PF13855.6 ETS76684.1 - 0.0008 19.1 0.8 0.02 14.7 0.4 3.2 2 0 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.6 ETS76684.1 - 0.0087 15.6 1.3 0.028 13.9 0.4 2.3 2 1 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 ETS76684.1 - 0.032 14.6 0.8 0.032 14.6 0.8 4.6 5 2 2 7 7 6 0 Leucine Rich repeats (2 copies) CDC27 PF09507.10 ETS76684.1 - 0.087 12.2 12.6 0.14 11.5 12.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Vps39_2 PF10367.9 ETS76684.1 - 0.16 12.4 0.5 1 9.8 0.0 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 CDC45 PF02724.14 ETS76684.1 - 0.18 10.1 4.8 0.24 9.6 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Shadoo PF14999.6 ETS76684.1 - 0.55 10.3 6.7 1.5 8.9 6.4 1.8 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective SbcD_C PF12320.8 ETS76684.1 - 2.7 8.4 5.8 0.54 10.6 0.1 2.6 2 1 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Ku_C PF03730.14 ETS76684.1 - 4.1 8.2 8.3 67 4.3 6.9 2.7 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm Ribosomal_60s PF00428.19 ETS76684.1 - 4.6 7.9 23.9 0.32 11.6 18.3 1.9 1 1 1 2 2 2 0 60s Acidic ribosomal protein RR_TM4-6 PF06459.12 ETS76684.1 - 5.1 6.9 12.9 8.5 6.1 12.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PGA2 PF07543.12 ETS76684.1 - 7.4 6.5 16.6 16 5.5 16.6 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 adh_short PF00106.25 ETS76685.1 - 5e-39 133.8 0.0 7.3e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS76685.1 - 5.8e-28 98.0 0.0 7.6e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 ETS76685.1 - 2.6e-07 30.7 0.2 4.9e-07 29.8 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 ETS76685.1 - 8.4e-06 25.8 0.2 1.8e-05 24.8 0.1 1.6 1 1 1 2 2 2 1 KR domain DUF1776 PF08643.10 ETS76685.1 - 6.1e-05 22.5 0.0 0.14 11.5 0.0 2.3 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 ETS76685.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ETS76685.1 - 0.0017 17.6 0.0 0.0031 16.7 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 ETS76685.1 - 0.024 14.2 0.1 0.035 13.7 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.18 ETS76685.1 - 0.059 13.6 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 ETS76685.1 - 0.061 13.9 0.1 0.12 12.9 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent EHN PF06441.12 ETS76686.1 - 3.1e-24 85.4 1.4 5.6e-24 84.6 1.4 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus TaqI_C PF12950.7 ETS76686.1 - 0.039 14.0 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain Pkinase PF00069.25 ETS76687.1 - 2.6e-05 23.7 0.0 0.0095 15.3 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS76687.1 - 4e-05 23.0 0.5 0.0066 15.8 0.5 3.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ETS76688.1 - 0.038 13.4 0.0 4.3 6.6 0.0 2.7 2 1 0 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.17 ETS76688.1 - 0.14 11.4 0.0 3.8 6.7 0.0 2.6 2 1 0 2 2 2 0 Protein tyrosine kinase NTF2 PF02136.20 ETS76689.1 - 7.5e-06 26.5 0.1 1.9e-05 25.2 0.1 1.6 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain PALP PF00291.25 ETS76690.1 - 6.4e-63 212.9 0.4 7.3e-63 212.7 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Hid1 PF12722.7 ETS76691.1 - 0 1034.0 0.0 0 1033.8 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 ETS76691.1 - 1.3e-102 344.3 0.0 1.6e-102 344.0 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF913 PF06025.12 ETS76691.1 - 0.0032 16.5 0.4 0.0059 15.6 0.4 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) MFS_1 PF07690.16 ETS76692.1 - 2.7e-19 69.3 79.9 1.4e-14 53.8 45.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PfkB PF00294.24 ETS76693.1 - 2.4e-17 63.2 0.0 3.9e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase cNMP_binding PF00027.29 ETS76693.1 - 0.068 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Sacchrp_dh_C PF16653.5 ETS76694.1 - 9.5e-97 324.2 0.0 3.8e-96 322.2 0.0 1.9 2 1 0 2 2 2 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 ETS76694.1 - 4.2e-24 85.2 0.1 6.5e-24 84.6 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 ETS76694.1 - 6.4e-05 22.9 0.1 0.00011 22.1 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 ETS76694.1 - 0.017 15.2 0.0 0.033 14.3 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 ETS76694.1 - 0.06 12.9 0.2 0.88 9.1 0.0 2.7 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF2948 PF11164.8 ETS76694.1 - 0.077 13.0 0.0 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2948) NAD_binding_3 PF03447.16 ETS76694.1 - 0.14 12.8 0.1 0.62 10.7 0.1 2.0 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Las1 PF04031.13 ETS76695.1 - 2.9e-59 199.6 0.3 4.1e-59 199.1 0.3 1.2 1 0 0 1 1 1 1 Las1-like HAGH_C PF16123.5 ETS76696.1 - 4.4e-22 78.4 0.7 6.9e-22 77.8 0.7 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 ETS76696.1 - 2.1e-16 60.5 2.6 3.1e-14 53.5 2.6 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS76696.1 - 0.0049 16.4 0.2 0.033 13.7 0.2 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Peripla_BP_4 PF13407.6 ETS76696.1 - 0.036 13.6 0.5 0.2 11.2 0.2 2.0 2 0 0 2 2 2 0 Periplasmic binding protein domain DUF1236 PF06823.12 ETS76696.1 - 0.12 12.3 0.1 0.97 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1236) PIG-Y PF15159.6 ETS76697.1 - 2.1e-22 79.8 9.1 3e-22 79.3 9.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 ETS76697.1 - 0.23 12.0 2.6 0.93 10.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Cation_efflux PF01545.21 ETS76698.1 - 1.6e-13 50.9 8.5 2.1e-13 50.4 8.5 1.1 1 0 0 1 1 1 1 Cation efflux family zf-MYND PF01753.18 ETS76699.1 - 1.3e-07 31.5 19.6 1.3e-07 31.5 19.6 2.1 2 0 0 2 2 2 1 MYND finger KCNQ_channel PF03520.14 ETS76699.1 - 0.099 12.5 1.5 0.12 12.2 0.1 1.7 2 0 0 2 2 2 0 KCNQ voltage-gated potassium channel MCM_lid PF17855.1 ETS76699.1 - 0.12 12.8 0.3 0.34 11.4 0.3 1.8 1 0 0 1 1 1 0 MCM AAA-lid domain SelP_N PF04592.14 ETS76699.1 - 0.24 10.8 18.0 1.4 8.2 4.0 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region IF4E PF01652.18 ETS76700.1 - 3.8e-35 121.0 0.8 5e-35 120.6 0.8 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Dehydratase_hem PF13816.6 ETS76700.1 - 0.063 12.7 0.1 0.095 12.1 0.1 1.2 1 0 0 1 1 1 0 Haem-containing dehydratase EF-hand_7 PF13499.6 ETS76701.1 - 0.0091 16.4 0.0 0.1 13.1 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 ETS76701.1 - 0.062 13.6 0.0 0.37 11.1 0.0 2.1 2 1 0 2 2 2 0 EF-hand domain DEAD PF00270.29 ETS76702.1 - 1.1e-49 168.6 0.0 3.5e-49 167.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS76702.1 - 3.2e-32 111.2 0.0 9e-32 109.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS76702.1 - 0.001 19.1 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ETS76702.1 - 0.024 14.0 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 ETS76702.1 - 0.22 10.7 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Proteasome PF00227.26 ETS76703.1 - 2.4e-30 105.5 0.0 2.7e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.32 ETS76704.1 - 7.6e-22 77.2 7.6 0.0003 21.5 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS76704.1 - 0.0025 18.1 0.0 0.094 13.0 0.0 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ETS76704.1 - 0.019 13.7 0.0 0.2 10.2 0.1 2.3 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ETS76704.1 - 0.14 10.9 0.0 0.57 8.9 0.0 2.0 2 0 0 2 2 2 0 Nup133 N terminal like Ras PF00071.22 ETS76705.1 - 5.2e-45 152.9 0.1 6e-45 152.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS76705.1 - 1.4e-15 57.5 0.0 2e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS76705.1 - 3.9e-06 26.4 0.0 4.2e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ETS76705.1 - 2.3e-05 24.0 0.0 0.00012 21.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ETS76705.1 - 0.00016 21.7 0.0 0.00025 21.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 ETS76705.1 - 0.0025 17.3 0.0 0.0063 16.0 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 ETS76705.1 - 0.0029 17.5 0.0 0.49 10.3 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_14 PF13173.6 ETS76705.1 - 0.021 14.8 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 ETS76705.1 - 0.029 13.9 0.0 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B tRNA-synt_2b PF00587.25 ETS76706.1 - 2.9e-37 128.4 0.0 4.9e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 ETS76706.1 - 2.6e-17 63.0 6.2 2.6e-17 63.0 6.2 2.2 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Peptidase_C78 PF07910.13 ETS76707.1 - 9.9e-68 227.8 0.0 1.6e-67 227.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.12 ETS76707.1 - 0.0022 18.2 5.5 0.33 11.3 0.5 3.2 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding Peptidase_C39_2 PF13529.6 ETS76707.1 - 0.027 15.0 0.0 0.056 14.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase_C39 like family zf_UBZ PF18439.1 ETS76707.1 - 0.029 13.9 3.3 0.061 12.9 3.3 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Lar_restr_allev PF14354.6 ETS76707.1 - 0.15 12.5 1.1 0.46 10.9 1.1 1.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF4223 PF13978.6 ETS76707.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) PRP21_like_P PF12230.8 ETS76707.1 - 0.17 11.7 0.3 0.67 9.8 0.0 1.9 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Peptidase_C47 PF05543.13 ETS76707.1 - 0.21 11.1 0.0 0.86 9.2 0.0 1.9 2 0 0 2 2 2 0 Staphopain peptidase C47 zf-ribbon_3 PF13248.6 ETS76707.1 - 0.26 10.8 1.3 6.6 6.3 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Ham1p_like PF01725.16 ETS76708.1 - 1.2e-30 106.8 0.0 1.3e-30 106.7 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Ham1p_like PF01725.16 ETS76709.1 - 5.6e-22 78.6 0.0 6.3e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.6 ETS76710.1 - 3.7e-27 95.4 0.5 1.1e-26 93.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 ETS76710.1 - 2.1e-07 31.4 0.1 1.1e-06 29.2 0.0 2.1 1 1 1 2 2 2 1 AAA domain ADK PF00406.22 ETS76710.1 - 3.5e-05 23.9 0.0 0.004 17.3 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA_28 PF13521.6 ETS76710.1 - 0.00011 22.4 0.5 0.00024 21.4 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ETS76710.1 - 0.00014 22.0 0.1 0.016 15.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 ETS76710.1 - 0.00033 20.6 2.9 0.12 12.2 0.0 2.1 1 1 1 2 2 2 2 Deoxynucleoside kinase AAA PF00004.29 ETS76710.1 - 0.00046 20.6 0.0 0.0014 19.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.22 ETS76710.1 - 0.001 19.2 0.2 0.0051 16.9 0.2 1.9 1 1 0 1 1 1 1 Shikimate kinase NTPase_1 PF03266.15 ETS76710.1 - 0.0025 17.7 0.2 0.0061 16.5 0.0 1.7 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.6 ETS76710.1 - 0.0032 17.7 0.0 0.01 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 ETS76710.1 - 0.0089 16.3 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain AAA_16 PF13191.6 ETS76710.1 - 0.0096 16.3 0.2 0.022 15.1 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain Thymidylate_kin PF02223.17 ETS76710.1 - 0.012 15.4 0.1 0.69 9.6 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase KTI12 PF08433.10 ETS76710.1 - 0.036 13.5 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Rad17 PF03215.15 ETS76710.1 - 0.041 13.8 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 ETS76710.1 - 0.053 13.2 0.5 0.15 11.7 0.3 2.1 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ETS76710.1 - 0.054 13.2 2.6 1.2 8.8 0.5 2.4 1 1 1 2 2 2 0 AAA domain RuvB_N PF05496.12 ETS76710.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 ETS76710.1 - 0.06 13.1 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 ETS76710.1 - 0.083 12.9 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ETS76710.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 ETS76710.1 - 0.16 12.3 1.5 0.2 12.0 0.4 1.7 1 1 1 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 ETS76710.1 - 0.16 11.7 0.2 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Myosin_head PF00063.21 ETS76711.1 - 1.5e-263 876.0 0.2 2.6e-263 875.3 0.2 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 ETS76711.1 - 3.2e-26 91.6 2.5 3.2e-26 91.6 2.5 2.5 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 ETS76711.1 - 2e-10 39.5 32.5 3.6e-06 26.3 2.0 6.9 6 0 0 6 6 6 2 IQ calmodulin-binding motif AAA_22 PF13401.6 ETS76711.1 - 0.0028 17.9 0.0 0.011 16.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_13 PF13166.6 ETS76711.1 - 0.0079 14.9 15.2 0.017 13.8 15.2 1.4 1 0 0 1 1 1 1 AAA domain DUF4201 PF13870.6 ETS76711.1 - 0.011 15.5 16.5 0.035 13.8 16.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) T2SSE PF00437.20 ETS76711.1 - 0.021 13.9 0.0 0.055 12.5 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Myosin_N PF02736.19 ETS76711.1 - 0.028 14.3 2.1 0.083 12.7 2.1 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain RNA_helicase PF00910.22 ETS76711.1 - 0.032 14.6 0.0 2 8.8 0.0 3.0 2 0 0 2 2 2 0 RNA helicase Dna2 PF08696.11 ETS76711.1 - 0.032 14.0 2.7 0.11 12.4 2.7 1.9 1 0 0 1 1 1 0 DNA replication factor Dna2 Baculo_PEP_C PF04513.12 ETS76711.1 - 0.04 14.0 10.6 0.27 11.3 8.9 2.9 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_16 PF13191.6 ETS76711.1 - 0.04 14.3 0.3 0.21 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain APG6_N PF17675.1 ETS76711.1 - 0.043 14.4 24.6 0.017 15.6 18.4 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region TraF_2 PF13729.6 ETS76711.1 - 0.057 12.8 0.7 0.13 11.6 0.7 1.6 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein TsaE PF02367.17 ETS76711.1 - 0.12 12.4 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF812 PF05667.11 ETS76711.1 - 0.18 10.6 21.5 0.34 9.7 21.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Sec34 PF04136.15 ETS76711.1 - 0.22 11.4 8.5 0.72 9.7 6.9 2.5 1 1 1 2 2 2 0 Sec34-like family IFP_35_N PF07334.13 ETS76711.1 - 0.22 11.6 3.2 0.57 10.3 1.7 2.5 2 0 0 2 2 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus KASH_CCD PF14662.6 ETS76711.1 - 0.23 11.2 21.8 0.087 12.6 4.8 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Snapin_Pallidin PF14712.6 ETS76711.1 - 0.37 11.2 15.1 0.6 10.6 2.7 3.4 2 1 0 2 2 2 0 Snapin/Pallidin GAS PF13851.6 ETS76711.1 - 0.48 9.7 26.3 2.1 7.6 12.6 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ABC_tran PF00005.27 ETS76711.1 - 0.57 10.7 3.4 2.3 8.8 0.0 2.8 2 0 0 2 2 2 0 ABC transporter ATG16 PF08614.11 ETS76711.1 - 0.66 10.2 24.2 2.2 8.4 12.2 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 ETS76711.1 - 0.7 9.9 24.3 62 3.6 12.4 2.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 ETS76711.1 - 0.75 10.0 23.0 0.28 11.4 5.4 2.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Seryl_tRNA_N PF02403.22 ETS76711.1 - 1.1 9.6 22.5 0.26 11.5 11.5 3.9 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4164 PF13747.6 ETS76711.1 - 1.4 9.3 10.3 4 7.8 9.1 2.4 1 1 1 2 2 1 0 Domain of unknown function (DUF4164) UPF0242 PF06785.11 ETS76711.1 - 2 8.5 20.6 0.7 10.0 14.6 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HAUS-augmin3 PF14932.6 ETS76711.1 - 2.4 7.6 22.5 1.1 8.8 9.3 2.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 BRE1 PF08647.11 ETS76711.1 - 3.2 7.9 20.3 6.3 6.9 17.1 3.0 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 ETS76711.1 - 4.3 7.4 25.7 2.9 8.0 21.1 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 ETS76711.1 - 4.8 7.3 12.3 24 5.0 0.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 ETS76711.1 - 4.8 6.4 22.3 3.1 7.0 10.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ADIP PF11559.8 ETS76711.1 - 5.2 7.2 19.5 5.6 7.0 8.9 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding GCN5L1 PF06320.13 ETS76711.1 - 5.5 7.2 16.3 15 5.7 6.1 2.9 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) DHR10 PF18595.1 ETS76711.1 - 6.1 6.9 24.7 4.3 7.4 3.2 3.0 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain TMF_TATA_bd PF12325.8 ETS76711.1 - 6.2 7.1 20.2 21 5.4 15.7 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.9 ETS76711.1 - 6.6 5.7 15.2 14 4.6 15.2 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 2-Hacid_dh_C PF02826.19 ETS76712.1 - 3.7e-51 173.0 0.0 5.6e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS76712.1 - 8.5e-36 122.6 0.0 1.1e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ETS76712.1 - 0.00026 21.2 0.1 0.00056 20.1 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 ETS76712.1 - 0.0082 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 ETS76712.1 - 0.0083 15.9 0.1 0.02 14.6 0.1 1.7 1 0 0 1 1 1 1 ACT domain IlvN PF07991.12 ETS76712.1 - 0.016 14.8 0.0 0.18 11.4 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAP PF00956.18 ETS76713.1 - 6e-100 333.9 9.9 6e-100 333.9 9.9 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Striatin PF08232.12 ETS76713.1 - 0.02 15.5 0.9 0.02 15.5 0.9 2.6 2 1 0 2 2 2 0 Striatin family P5-ATPase PF12409.8 ETS76714.1 - 2.4e-42 144.0 0.2 5.9e-41 139.5 0.0 2.6 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 ETS76714.1 - 5.1e-31 107.6 0.0 1.7e-30 105.9 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ETS76714.1 - 1.4e-14 54.8 0.1 1.1e-06 29.1 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ETS76714.1 - 0.0028 17.3 0.0 0.0063 16.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ETS76714.1 - 0.018 15.1 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) WAPL PF07814.13 ETS76715.1 - 2.2e-57 194.5 0.0 3.2e-57 194.0 0.0 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.6 ETS76716.1 - 1.3e-80 269.7 0.0 1.6e-80 269.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 ETS76716.1 - 0.0063 16.0 0.0 0.0088 15.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Elf1 PF05129.13 ETS76717.1 - 9e-29 99.4 0.3 1.3e-28 98.8 0.3 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like PHD_4 PF16866.5 ETS76717.1 - 0.24 11.5 2.2 0.2 11.8 0.6 1.6 2 0 0 2 2 2 0 PHD-finger GTP_CH_N PF12471.8 ETS76718.1 - 3.6e-91 304.2 0.0 5e-91 303.7 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 ETS76718.1 - 1.7e-17 63.5 0.0 2.6e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Ribosomal_S3Ae PF01015.18 ETS76720.1 - 4.9e-90 300.5 1.0 6e-90 300.2 1.0 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 ETS76720.1 - 0.026 15.0 0.1 0.12 12.9 0.0 2.1 2 0 0 2 2 2 0 Translation initiation factor SUI1 NEMO PF11577.8 ETS76720.1 - 0.04 13.9 0.5 0.31 11.1 0.0 2.4 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Ras PF00071.22 ETS76721.1 - 4.5e-48 162.9 0.0 5.1e-48 162.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS76721.1 - 8.8e-31 106.6 0.0 1.7e-30 105.7 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS76721.1 - 1.5e-12 47.4 0.0 1.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ETS76721.1 - 3.5e-06 27.1 0.0 5.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ETS76721.1 - 6.4e-06 25.7 0.0 7.7e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ETS76721.1 - 0.00011 21.8 0.0 0.0012 18.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 ETS76721.1 - 0.0013 18.9 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 ETS76721.1 - 0.0028 17.1 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 ETS76721.1 - 0.0057 17.2 0.0 0.0071 16.9 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 ETS76721.1 - 0.0084 16.5 0.0 0.0099 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ETS76721.1 - 0.0091 15.7 0.2 0.021 14.6 0.0 1.6 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 ETS76721.1 - 0.016 15.2 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 ETS76721.1 - 0.052 13.4 0.0 0.17 11.8 0.0 1.9 1 1 1 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 ETS76721.1 - 0.056 13.0 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 ETS76721.1 - 0.064 13.5 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 ETS76721.1 - 0.071 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 ETS76721.1 - 0.076 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 ETS76721.1 - 0.22 10.9 0.0 0.37 10.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ATP_bind_1 PF03029.17 ETS76721.1 - 0.24 11.2 0.0 9.3 6.0 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Abhydrolase_1 PF00561.20 ETS76722.1 - 2e-22 80.1 0.1 1.8e-20 73.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS76722.1 - 1.1e-15 58.8 0.0 1.7e-15 58.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS76722.1 - 9.5e-10 38.1 0.3 1.6e-09 37.4 0.3 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 ETS76722.1 - 2e-05 24.8 0.0 3.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 ETS76722.1 - 3.8e-05 23.5 0.0 0.016 15.0 0.0 2.2 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 ETS76722.1 - 0.075 12.9 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Esterase PF00756.20 ETS76722.1 - 0.08 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Zn_clus PF00172.18 ETS76723.1 - 0.01 16.0 11.2 0.022 14.9 11.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ETS76724.1 - 2.2e-41 142.0 50.3 2.2e-41 142.0 50.3 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS76724.1 - 5.2e-14 51.6 23.2 8.5e-14 50.9 23.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HET PF06985.11 ETS76725.1 - 1.7e-22 80.3 0.4 4.5e-22 79.0 0.4 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 ETS76726.1 - 2.2e-06 27.7 0.0 4.2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.13 ETS76726.1 - 0.00045 20.0 0.0 0.00095 18.9 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein AAA_16 PF13191.6 ETS76726.1 - 0.00094 19.6 0.0 0.0035 17.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS76726.1 - 0.0026 18.0 0.0 0.012 15.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF676 PF05057.14 ETS76726.1 - 0.0051 16.3 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) ATPase_2 PF01637.18 ETS76726.1 - 0.0063 16.5 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 ETS76726.1 - 0.025 15.0 0.0 0.096 13.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ETS76726.1 - 0.038 13.7 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ETS76726.1 - 0.054 13.6 0.0 0.15 12.2 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 ETS76726.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ETS76726.1 - 0.16 11.2 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.6 ETS76726.1 - 0.17 12.3 0.1 0.58 10.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain Hydrolase_4 PF12146.8 ETS76726.1 - 0.18 11.1 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 NTPase_1 PF03266.15 ETS76726.1 - 0.18 11.7 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 NTPase cobW PF02492.19 ETS76726.1 - 0.21 11.1 0.0 0.56 9.8 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain tRNA-synt_2 PF00152.20 ETS76727.1 - 1.2e-85 287.3 0.0 1.9e-85 286.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ETS76727.1 - 1.6e-07 31.2 0.0 3.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 ETS76727.1 - 0.07 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain VIT1 PF01988.19 ETS76727.1 - 0.39 10.6 1.0 0.8 9.5 0.0 1.9 2 0 0 2 2 2 0 VIT family RRM_1 PF00076.22 ETS76728.1 - 1.5e-36 124.0 0.1 2.5e-11 43.2 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ETS76728.1 - 1.1e-17 63.6 0.0 0.0094 15.8 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 ETS76728.1 - 2.3e-08 33.6 3.0 2.3e-08 33.6 3.0 3.8 3 1 0 3 3 3 1 Putative RRM domain RRM_7 PF16367.5 ETS76728.1 - 2.7e-05 24.2 0.0 0.18 11.9 0.0 3.8 4 0 0 4 4 4 2 RNA recognition motif DUF4523 PF15023.6 ETS76728.1 - 4.7e-05 23.3 0.0 0.007 16.2 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.6 ETS76728.1 - 0.0015 18.5 0.0 1.8 8.7 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 ETS76728.1 - 0.0072 16.3 0.1 0.37 10.9 0.1 2.8 3 0 0 3 3 3 1 RNA binding motif RNA_bind PF08675.11 ETS76728.1 - 0.061 13.4 0.6 0.26 11.3 0.0 2.4 3 0 0 3 3 3 0 RNA binding domain His_Phos_2 PF00328.22 ETS76729.1 - 2.2e-15 56.9 0.0 2e-13 50.4 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPR_2 PF13041.6 ETS76730.1 - 3.2e-27 94.4 0.3 1.6e-08 34.6 0.1 7.2 5 2 2 7 7 7 5 PPR repeat family PPR_3 PF13812.6 ETS76730.1 - 6.8e-17 61.3 0.1 5.2e-05 23.2 0.0 5.4 4 1 1 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.20 ETS76730.1 - 1e-12 47.4 0.2 0.26 11.6 0.0 6.9 6 0 0 6 6 6 3 PPR repeat PPR_long PF17177.4 ETS76730.1 - 1.5e-08 34.2 0.0 0.0012 18.2 0.0 3.3 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ETS76730.1 - 0.0003 20.4 0.7 6.8 6.5 0.1 5.0 5 0 0 5 5 5 1 PPR repeat TPR_19 PF14559.6 ETS76730.1 - 0.0008 19.9 0.6 0.68 10.5 0.6 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 ETS76730.1 - 0.046 14.5 3.3 14 6.8 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat SMP PF04927.12 ETS76731.1 - 0.0064 16.9 12.0 0.54 10.8 0.4 3.9 3 2 2 5 5 5 3 Seed maturation protein DUF4834 PF16118.5 ETS76732.1 - 0.027 15.4 0.2 0.14 13.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CPSF100_C PF13299.6 ETS76732.1 - 0.074 13.2 0.2 0.12 12.6 0.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Equine_IAV_S2 PF06502.11 ETS76732.1 - 0.083 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein RskA PF10099.9 ETS76733.1 - 0.014 15.7 0.1 0.02 15.2 0.1 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA FA_hydroxylase PF04116.13 ETS76734.1 - 4.3e-23 82.1 11.8 4.3e-23 82.1 11.8 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TCTP PF00838.17 ETS76735.1 - 1.3e-56 191.5 2.1 1.5e-56 191.3 2.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein PSII_Pbs27 PF13326.6 ETS76735.1 - 0.04 14.2 0.3 0.053 13.8 0.3 1.1 1 0 0 1 1 1 0 Photosystem II Pbs27 Ribosomal_S20p PF01649.18 ETS76735.1 - 0.089 13.4 1.3 0.11 13.1 0.6 1.5 2 0 0 2 2 2 0 Ribosomal protein S20 AIM3 PF17096.5 ETS76736.1 - 0.0079 17.1 3.1 0.0079 17.1 3.1 4.5 4 2 1 5 5 5 1 Altered inheritance of mitochondria protein 3 DUF4054 PF13262.6 ETS76736.1 - 0.54 10.3 3.0 6.8 6.8 3.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4054) Mis12 PF05859.12 ETS76737.1 - 3.8e-45 153.3 0.0 6.7e-45 152.5 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein PhyH PF05721.13 ETS76741.1 - 1.4e-20 74.4 0.0 2.1e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 ETS76741.1 - 0.0021 18.9 0.0 0.0043 17.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SCP2 PF02036.17 ETS76741.1 - 0.1 13.1 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 SCP-2 sterol transfer family DUF2854 PF11016.8 ETS76741.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) 2OG-FeII_Oxy_5 PF13759.6 ETS76741.1 - 0.15 12.5 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF1479 PF07350.12 ETS76741.1 - 0.18 10.5 0.0 0.3 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) GMC_oxred_N PF00732.19 ETS76742.1 - 1e-56 192.5 0.0 1.3e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS76742.1 - 1e-35 123.4 0.0 2.3e-35 122.2 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 ETS76742.1 - 1.3e-05 25.0 0.2 0.00012 21.8 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS76742.1 - 3.4e-05 24.0 0.2 7.9e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS76742.1 - 0.00071 18.8 0.1 0.0012 18.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ETS76742.1 - 0.00071 18.7 0.1 0.001 18.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ETS76742.1 - 0.0072 15.6 0.0 0.019 14.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS76742.1 - 0.039 13.2 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS76742.1 - 0.04 13.2 0.1 0.064 12.5 0.1 1.2 1 0 0 1 1 1 0 Thi4 family COX5A PF02284.16 ETS76742.1 - 0.11 12.5 0.0 0.57 10.2 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va HI0933_like PF03486.14 ETS76742.1 - 0.19 10.4 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DNA_ligase_A_M PF01068.21 ETS76746.1 - 6.8e-61 205.5 1.3 1.1e-58 198.3 1.3 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ETS76746.1 - 1.5e-45 155.7 0.0 3.5e-45 154.4 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 ETS76746.1 - 4.9e-29 100.9 0.0 3.2e-28 98.2 0.0 2.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 ETS76746.1 - 3.6e-05 24.1 0.4 6.1e-05 23.4 0.4 1.4 1 0 0 1 1 1 1 RNA ligase MaoC_dehydratas PF01575.19 ETS76747.1 - 0.046 13.3 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 MaoC like domain Pkinase PF00069.25 ETS76748.1 - 4.9e-69 232.6 0.0 7.3e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS76748.1 - 1.6e-49 168.5 0.0 2.8e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 ETS76748.1 - 3.3e-27 94.8 0.0 6.1e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 ETS76748.1 - 5.3e-16 58.5 0.2 1.4e-15 57.2 0.1 1.8 2 0 0 2 2 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ETS76748.1 - 8.2e-16 58.2 0.1 1.6e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 ETS76748.1 - 4.8e-14 52.7 0.0 8.6e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 ETS76748.1 - 5.7e-06 25.8 0.0 0.0019 17.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_4 PF18017.1 ETS76748.1 - 0.022 14.7 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 ETS76748.1 - 0.023 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Pkinase_fungal PF17667.1 ETS76748.1 - 0.045 12.5 0.0 0.085 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase GhoS PF11080.8 ETS76748.1 - 0.11 12.5 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 Endoribonuclease GhoS Seadorna_VP7 PF07387.11 ETS76748.1 - 0.23 10.5 0.0 0.44 9.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 LRR_1 PF00560.33 ETS76749.1 - 1.4 9.8 11.9 45 5.2 0.1 6.6 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_6 PF13516.6 ETS76749.1 - 4.7 7.5 11.8 50 4.3 0.1 6.3 7 0 0 7 7 7 0 Leucine Rich repeat Pkinase PF00069.25 ETS76750.1 - 0.0023 17.4 0.0 0.14 11.5 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS76750.1 - 0.0048 16.2 0.0 0.53 9.5 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Ceramidase PF05875.12 ETS76752.1 - 2.3e-61 207.5 0.2 2.8e-61 207.2 0.2 1.0 1 0 0 1 1 1 1 Ceramidase DUF4401 PF14351.6 ETS76752.1 - 0.0054 16.1 3.6 0.0054 16.1 3.6 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4401) SET PF00856.28 ETS76754.1 - 1.4e-10 41.8 0.2 1.5e-09 38.5 0.2 2.3 1 1 0 1 1 1 1 SET domain SAF PF08666.12 ETS76754.1 - 0.042 14.5 0.0 12 6.6 0.0 2.4 2 0 0 2 2 2 0 SAF domain HET PF06985.11 ETS76755.1 - 1.8e-21 77.0 0.0 4.4e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ETS76756.1 - 3.6e-10 40.4 1.4 3.6e-10 40.4 1.4 4.3 2 2 1 3 3 3 2 Heterokaryon incompatibility protein (HET) FapA PF03961.13 ETS76756.1 - 0.55 8.8 5.8 0.97 8.0 5.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A FXR_C1 PF16096.5 ETS76756.1 - 0.73 10.1 10.9 2.1 8.6 10.9 1.7 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 Ank_2 PF12796.7 ETS76757.1 - 4.2e-58 193.9 17.2 2.6e-14 53.6 0.2 7.6 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS76757.1 - 1.5e-41 140.2 18.7 4.7e-08 33.4 0.1 10.6 5 3 4 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS76757.1 - 7.3e-35 118.6 13.1 1.6e-05 25.1 0.0 9.3 6 3 3 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS76757.1 - 4e-29 97.4 15.6 0.013 15.9 0.0 13.3 14 0 0 14 14 14 6 Ankyrin repeat Ank PF00023.30 ETS76757.1 - 1.6e-25 88.3 20.9 0.011 16.2 0.0 11.3 11 1 0 11 11 11 7 Ankyrin repeat CorA PF01544.18 ETS76757.1 - 2.5e-08 33.6 0.4 7e-08 32.1 0.1 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein AAA PF00004.29 ETS76758.1 - 5.2e-17 62.5 0.0 1.2e-16 61.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS76758.1 - 0.00031 21.2 0.5 0.0013 19.1 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS76758.1 - 0.00043 20.6 1.6 0.0053 17.0 0.1 3.1 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 ETS76758.1 - 0.00049 20.1 0.0 0.0012 18.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 ETS76758.1 - 0.014 15.5 0.1 0.04 14.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ETS76758.1 - 0.023 14.4 0.2 0.063 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 ETS76758.1 - 0.03 14.0 0.0 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 ETS76758.1 - 0.031 14.1 1.4 0.073 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 ETS76758.1 - 0.051 12.9 0.1 0.19 11.1 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF1845 PF08900.11 ETS76758.1 - 0.058 13.1 0.3 0.18 11.5 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1845) AAA_3 PF07726.11 ETS76758.1 - 0.067 13.1 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 ETS76758.1 - 0.13 12.8 0.2 1.3 9.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.12 ETS76758.1 - 0.19 11.5 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain UBA_4 PF14555.6 ETS76759.1 - 0.023 14.5 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain TAF1_subA PF14929.6 ETS76760.1 - 0.0099 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A SNAP PF14938.6 ETS76760.1 - 0.056 12.9 0.2 0.17 11.2 0.1 1.7 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP Fungal_trans_2 PF11951.8 ETS76762.1 - 6.4e-05 21.9 0.0 0.00012 21.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 ETS76763.1 - 7.7e-19 67.9 0.4 7.6e-17 61.4 0.3 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 ETS76763.1 - 1.9e-13 50.7 0.1 3.3e-13 49.9 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ETS76763.1 - 3.7e-11 43.0 0.4 5.4e-09 35.9 0.2 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase COesterase PF00135.28 ETS76764.1 - 1.2e-79 268.5 0.0 2.2e-71 241.3 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS76764.1 - 2.5e-10 40.6 0.1 2.2e-09 37.5 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.22 ETS76765.1 - 1.4e-42 146.0 0.0 2e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Neurochondrin PF05536.11 ETS76766.1 - 2.9e-69 234.0 3.6 3.9e-69 233.6 3.6 1.1 1 0 0 1 1 1 1 Neurochondrin RIX1 PF08167.12 ETS76766.1 - 0.048 13.4 0.8 0.25 11.0 0.0 2.6 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis Voltage_CLC PF00654.20 ETS76767.1 - 2.8e-88 296.6 28.9 2.8e-88 296.6 28.9 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 ETS76767.1 - 1.1e-05 25.7 0.0 0.12 12.8 0.0 2.5 2 0 0 2 2 2 2 CBS domain GTP_EFTU_D4 PF14578.6 ETS76767.1 - 0.15 12.0 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 LacI PF00356.21 ETS76767.1 - 0.54 10.1 2.0 1.1 9.1 2.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family zf-C3HC4_3 PF13920.6 ETS76768.1 - 9e-10 38.3 8.9 1.3e-09 37.8 8.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ETS76768.1 - 4.2e-07 29.7 9.9 7.1e-07 29.0 9.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 ETS76768.1 - 9.5e-07 28.6 12.4 1.5e-06 27.9 12.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ETS76768.1 - 1.5e-06 28.4 11.6 2.3e-06 27.8 11.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ETS76768.1 - 2.2e-06 27.5 11.0 3.5e-06 26.9 11.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ETS76768.1 - 3.3e-06 27.0 9.5 8.9e-06 25.6 5.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ETS76768.1 - 4.2e-06 26.5 11.6 6.4e-06 25.9 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ETS76768.1 - 0.00018 21.5 5.0 0.0003 20.8 5.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 ETS76768.1 - 0.0052 16.5 5.7 0.0094 15.7 5.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 ETS76768.1 - 0.018 15.3 7.7 0.032 14.5 7.7 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 ETS76768.1 - 0.074 13.2 8.5 0.13 12.4 8.5 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TerY_C PF15616.6 ETS76768.1 - 0.091 12.9 2.1 0.17 12.0 2.1 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_6 PF14835.6 ETS76768.1 - 0.14 12.0 3.4 0.25 11.2 3.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 ETS76768.1 - 0.47 10.2 10.0 0.22 11.3 6.4 2.1 2 0 0 2 2 2 0 RING-like zinc finger DZR PF12773.7 ETS76768.1 - 2.2 8.4 4.8 4.6 7.3 4.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon IBR PF01485.21 ETS76768.1 - 6 7.2 7.2 14 6.0 7.2 1.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain CN_hydrolase PF00795.22 ETS76769.1 - 0.004 16.5 0.0 0.0049 16.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Methyltransf_25 PF13649.6 ETS76770.1 - 2.1e-07 31.5 0.0 7.5e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS76770.1 - 5.3e-06 26.4 0.0 7.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ETS76770.1 - 9.9e-06 25.4 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ETS76770.1 - 0.0002 21.2 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS76770.1 - 0.0062 15.9 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 ETS76770.1 - 0.0087 15.4 0.0 0.048 13.0 0.0 1.9 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 ETS76770.1 - 0.0098 16.5 0.1 0.027 15.1 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 ETS76770.1 - 0.01 16.9 0.5 0.031 15.3 0.3 2.0 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 ETS76770.1 - 0.012 16.4 0.0 0.044 14.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 ETS76770.1 - 0.03 13.9 0.0 0.074 12.6 0.0 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_16 PF10294.9 ETS76770.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 Lysine methyltransferase SO_alpha_A3 PF17806.1 ETS76770.1 - 0.094 13.1 0.4 0.31 11.4 0.0 2.0 2 0 0 2 2 2 0 Sarcosine oxidase A3 domain Imm48 PF15574.6 ETS76770.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 48 Fibrillarin PF01269.17 ETS76770.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin DNApol_Exo PF18136.1 ETS76771.1 - 1.5e-104 349.2 0.0 2.6e-104 348.3 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 ETS76771.1 - 2.4e-53 181.6 0.0 3.9e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A Methyltransf_2 PF00891.18 ETS76773.1 - 1.2e-25 90.1 0.0 1.9e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 ETS76773.1 - 0.0086 16.8 0.0 0.018 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS76773.1 - 0.048 13.4 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 ETS76773.1 - 0.17 12.6 0.0 0.35 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.19 ETS76776.1 - 5e-21 75.3 0.0 1.3e-20 73.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ETS76776.1 - 6.7e-06 26.2 0.9 1.4e-05 25.2 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS76776.1 - 0.00015 21.1 0.2 0.0038 16.5 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS76776.1 - 0.00022 20.9 0.4 0.0008 19.1 0.3 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS76776.1 - 0.00027 20.3 0.1 0.0045 16.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS76776.1 - 0.00052 20.5 0.2 0.0011 19.5 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ETS76776.1 - 0.0023 17.0 0.0 0.96 8.4 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase FAD_binding_2 PF00890.24 ETS76776.1 - 0.027 13.6 0.1 0.043 12.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 ETS76776.1 - 0.14 10.9 0.2 0.36 9.5 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.23 ETS76776.1 - 0.14 12.1 0.1 0.57 10.2 0.0 2.1 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HET PF06985.11 ETS76777.1 - 2.2e-32 112.4 3.5 3.8e-32 111.6 3.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HAUS-augmin3 PF14932.6 ETS76778.1 - 0.065 12.8 0.0 0.07 12.7 0.0 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 AA_permease PF00324.21 ETS76779.1 - 5.8e-131 437.4 32.4 6.7e-131 437.2 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS76779.1 - 4.7e-45 154.2 38.7 5.7e-45 153.9 38.7 1.0 1 0 0 1 1 1 1 Amino acid permease Nup192 PF11894.8 ETS76780.1 - 0 1391.9 0.0 0 1391.7 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup188 PF10487.9 ETS76780.1 - 0.0062 14.5 0.0 0.017 13.1 0.0 1.7 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 PI3_PI4_kinase PF00454.27 ETS76781.1 - 8.5e-52 176.4 0.0 2.1e-51 175.2 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 ETS76781.1 - 2.1e-35 122.1 0.3 2.1e-35 122.1 0.3 3.6 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 ETS76781.1 - 1.3e-10 40.9 0.0 3.1e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 FATC domain DUF745 PF05335.13 ETS76781.1 - 7.6 6.2 7.8 0.44 10.3 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Arginase PF00491.21 ETS76783.1 - 1.5e-89 300.3 0.0 1.9e-89 299.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 ETS76783.1 - 0.038 14.2 0.8 0.061 13.5 0.5 1.4 1 1 0 1 1 1 0 UPF0489 domain Ras PF00071.22 ETS76784.1 - 6.5e-53 178.6 0.0 8.8e-53 178.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS76784.1 - 5.1e-19 68.7 0.0 9e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS76784.1 - 4.2e-07 29.6 0.0 5.4e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family bMG5 PF17972.1 ETS76785.1 - 0.016 15.5 0.8 0.037 14.4 0.0 1.9 2 1 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG5 domain DnaJ PF00226.31 ETS76786.1 - 1.8e-22 79.3 0.3 3.9e-22 78.1 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain zf-CCHC PF00098.23 ETS76786.1 - 4.4e-10 39.2 21.9 1.7e-06 27.8 1.2 3.6 3 0 0 3 3 3 2 Zinc knuckle RRM_1 PF00076.22 ETS76786.1 - 0.014 15.2 0.1 0.06 13.2 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.6 ETS76786.1 - 0.14 11.9 11.6 0.55 10.0 1.0 3.1 3 0 0 3 3 3 0 Zinc knuckle SAPS PF04499.15 ETS76786.1 - 0.71 8.6 7.4 1 8.1 7.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mgr1 PF08602.10 ETS76786.1 - 1.9 7.2 5.8 3.3 6.4 5.8 1.3 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF4448 PF14610.6 ETS76787.1 - 5.5e-27 94.8 0.0 7e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Insulin_TMD PF17870.1 ETS76787.1 - 0.015 15.3 0.1 0.027 14.5 0.1 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Gram_pos_anchor PF00746.21 ETS76787.1 - 0.25 11.3 1.5 0.55 10.2 1.5 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif HAD_2 PF13419.6 ETS76788.1 - 5.8e-08 33.0 0.0 1.5e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETS76788.1 - 1.3e-07 32.2 0.0 1.6e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ETS76788.1 - 0.035 14.2 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Bac_luciferase PF00296.20 ETS76789.1 - 1.8e-55 188.6 0.4 2.3e-55 188.2 0.4 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Amidohydro_2 PF04909.14 ETS76789.1 - 0.018 14.8 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Amidohydrolase SSF PF00474.17 ETS76790.1 - 9.7e-23 80.7 32.3 1.7e-22 79.9 32.3 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3693 PF12472.8 ETS76790.1 - 4.2 7.1 6.2 3.1 7.5 1.1 2.9 2 0 0 2 2 2 0 Phage related protein Stealth_CR4 PF17103.5 ETS76791.1 - 0.22 11.4 0.0 0.38 10.7 0.0 1.3 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 RINGv PF12906.7 ETS76792.1 - 4.2e-17 62.0 8.8 7.3e-17 61.2 8.8 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 ETS76792.1 - 0.013 15.8 8.6 0.022 15.1 8.6 1.4 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 ETS76792.1 - 0.18 11.9 2.3 0.38 10.8 2.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 ETS76792.1 - 1.8 8.5 5.2 3.5 7.6 5.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 ETS76792.1 - 4.6 7.1 6.4 8 6.3 6.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF842 PF05811.13 ETS76794.1 - 0.028 14.1 1.8 0.61 9.8 0.1 3.4 4 0 0 4 4 4 0 Eukaryotic protein of unknown function (DUF842) MFS_1 PF07690.16 ETS76795.1 - 2.5e-31 108.9 21.0 2.5e-31 108.9 21.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 ETS76795.1 - 0.5 10.2 1.9 6.7 6.6 0.0 3.1 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain p450 PF00067.22 ETS76796.1 - 2.2e-49 168.5 0.0 3.4e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF3299 PF11736.8 ETS76796.1 - 0.093 12.7 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) Agro_virD5 PF04730.12 ETS76796.1 - 0.21 10.1 0.2 0.33 9.4 0.2 1.2 1 0 0 1 1 1 0 Agrobacterium VirD5 protein p450 PF00067.22 ETS76797.1 - 6.3e-56 190.0 0.0 1.3e-55 189.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF2633 PF11119.8 ETS76797.1 - 0.14 12.1 1.1 0.3 11.0 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) tRNA-synt_1d PF00750.19 ETS76798.1 - 1.7e-100 336.4 2.5 2.4e-100 335.9 2.5 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 ETS76798.1 - 2.2e-26 92.3 0.2 6.2e-26 90.9 0.2 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain DUF2430 PF10353.9 ETS76798.1 - 0.16 12.4 0.2 0.69 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2430) Ferric_reduct PF01794.19 ETS76799.1 - 6.7e-20 71.5 13.5 6.7e-20 71.5 13.5 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ETS76799.1 - 1e-14 54.5 0.1 3.7e-14 52.7 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 ETS76799.1 - 4.1e-12 46.5 0.1 6.1e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain COesterase PF00135.28 ETS76801.1 - 2.9e-89 300.3 0.0 3.8e-89 299.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS76801.1 - 0.0026 17.6 0.3 0.015 15.1 0.0 2.2 3 0 0 3 3 3 1 alpha/beta hydrolase fold FAD_binding_4 PF01565.23 ETS76802.1 - 1.7e-28 99.1 1.4 2.9e-28 98.3 1.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS76802.1 - 1.7e-10 40.8 0.0 3.1e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like TPP_enzyme_N PF02776.18 ETS76803.1 - 3e-41 140.9 0.0 1.3e-40 138.8 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ETS76803.1 - 1.4e-20 73.7 0.0 1.4e-20 73.7 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ETS76803.1 - 8.1e-12 45.1 0.0 3.5e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Herpes_UL73 PF03554.13 ETS76803.1 - 0.33 11.0 2.2 0.67 10.0 2.2 1.4 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein HpcH_HpaI PF03328.14 ETS76804.1 - 3.8e-34 117.8 0.0 5e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 ETS76804.1 - 0.16 10.9 1.2 0.4 9.5 0.8 1.6 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain adh_short PF00106.25 ETS76805.1 - 3.8e-36 124.4 0.0 1.6e-30 106.1 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS76805.1 - 1.3e-32 113.3 0.1 4.1e-18 65.8 0.0 2.6 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS76805.1 - 7e-12 45.6 0.1 2e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 ETS76805.1 - 0.0057 16.6 0.4 0.013 15.4 0.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ETS76805.1 - 0.022 15.3 0.4 0.084 13.5 0.2 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Glyco_tran_WecB PF03808.13 ETS76805.1 - 0.037 14.0 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family SKI PF01202.22 ETS76805.1 - 0.15 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase AdoHcyase_NAD PF00670.21 ETS76805.1 - 0.17 11.9 5.2 7.3 6.6 5.2 2.3 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Sugar_tr PF00083.24 ETS76806.1 - 5.1e-73 246.5 19.4 6.3e-73 246.2 19.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS76806.1 - 4.1e-25 88.5 50.4 1.1e-23 83.7 26.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS76806.1 - 0.00031 19.5 1.7 0.00031 19.5 1.7 3.2 3 0 0 3 3 3 2 MFS/sugar transport protein PhyH PF05721.13 ETS76807.1 - 9.2e-06 26.1 0.0 1.3e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ADH_zinc_N PF00107.26 ETS76808.1 - 3.1e-12 46.6 0.1 9.5e-11 41.8 0.1 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS76808.1 - 4.4e-05 23.1 0.0 0.033 13.7 0.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ETS76808.1 - 0.00011 23.2 0.0 0.00026 22.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 ETS76808.1 - 0.0082 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 ETS76808.1 - 0.058 14.1 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 ETS76808.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N PF08240.12 ETS76809.1 - 5.5e-08 32.7 0.3 7.4e-08 32.3 0.3 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SOG2 PF10428.9 ETS76810.1 - 2.3 7.3 5.6 2.6 7.1 5.6 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Fungal_trans PF04082.18 ETS76811.1 - 0.00094 18.3 0.2 0.002 17.2 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain FMN_dh PF01070.18 ETS76812.1 - 4.2e-117 391.1 0.0 5e-117 390.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ETS76812.1 - 2.9e-08 33.2 0.1 6.9e-08 32.0 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 ETS76812.1 - 1.6e-05 24.5 3.5 0.014 14.8 0.2 3.0 1 1 2 3 3 3 2 Nitronate monooxygenase IMPDH PF00478.25 ETS76812.1 - 1.9e-05 23.8 6.3 8.4e-05 21.7 0.9 3.1 1 1 2 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 ETS76812.1 - 0.00039 19.9 0.8 0.17 11.4 0.0 2.8 2 1 0 2 2 2 2 Histidine biosynthesis protein Dus PF01207.17 ETS76812.1 - 0.0013 17.9 0.2 0.029 13.5 0.0 2.2 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 ETS76812.1 - 0.0018 17.5 0.2 0.017 14.4 0.0 2.1 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.14 ETS76812.1 - 0.0076 15.6 0.1 2 7.6 0.0 2.7 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 ETS76812.1 - 0.025 14.0 0.0 0.86 9.0 0.0 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Cyclin PF08613.11 ETS76813.1 - 7.2e-45 153.2 0.0 1.9e-44 151.9 0.0 1.8 1 1 0 1 1 1 1 Cyclin Pex14_N PF04695.13 ETS76813.1 - 2.7 8.6 8.9 0.2 12.3 2.5 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_M24 PF00557.24 ETS76814.1 - 1.3e-57 194.9 0.0 1.6e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ETS76814.1 - 1.7e-25 89.1 0.0 7.4e-25 87.1 0.0 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain DAO PF01266.24 ETS76815.1 - 3.2e-60 204.6 1.1 1.7e-59 202.2 1.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS76815.1 - 3.8e-07 29.6 0.0 0.008 15.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS76815.1 - 1.1e-06 29.1 0.0 0.073 13.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS76815.1 - 6.9e-06 26.2 0.0 1.7e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS76815.1 - 0.0011 18.9 0.0 0.26 11.3 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 ETS76815.1 - 0.0041 16.0 0.0 1.7 7.4 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase MCRA PF06100.11 ETS76815.1 - 0.015 14.1 0.0 0.67 8.7 0.0 2.1 2 0 0 2 2 2 0 MCRA family Amino_oxidase PF01593.24 ETS76815.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 ETS76815.1 - 0.029 13.7 0.2 0.081 12.3 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ETS76815.1 - 0.067 12.4 0.0 9.8 5.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 ETS76815.1 - 0.17 11.1 0.0 0.38 10.0 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Peptidase_S10 PF00450.22 ETS76816.1 - 9e-83 279.0 0.9 1.3e-82 278.5 0.9 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.16 ETS76817.1 - 3.8e-39 134.6 22.1 3.8e-39 134.6 22.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MCR_alpha PF02249.17 ETS76817.1 - 0.066 13.7 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain BBP2 PF07642.11 ETS76817.1 - 0.17 11.0 0.2 0.25 10.5 0.2 1.2 1 0 0 1 1 1 0 Putative beta-barrel porin-2, OmpL-like. bbp2 Phage_tail_NK PF16532.5 ETS76819.1 - 0.082 12.5 0.0 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 Sf6-type phage tail needle knob or tip of some Caudovirales OTT_1508_deam PF14441.6 ETS76819.1 - 0.085 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 OTT_1508-like deaminase ADH_N PF08240.12 ETS76820.1 - 4.5e-22 78.0 0.2 8.2e-22 77.2 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS76820.1 - 3e-16 59.6 0.0 4.9e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ETS76820.1 - 8.6e-05 22.0 0.1 0.00013 21.4 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ETS76820.1 - 0.0017 17.7 0.1 0.0026 17.1 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 ETS76820.1 - 0.011 15.7 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HeLo PF14479.6 ETS76821.1 - 2.3e-09 37.4 5.0 5.5e-05 23.1 0.1 2.9 2 1 1 3 3 3 2 Prion-inhibition and propagation Kdo PF06293.14 ETS76821.1 - 0.017 14.5 0.0 0.042 13.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_28 PF00295.17 ETS76822.1 - 1.4e-38 132.7 8.2 2e-38 132.3 8.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 ETS76822.1 - 0.072 12.9 15.9 0.13 12.1 14.0 2.3 1 1 1 2 2 2 0 Right handed beta helix region DUF1768 PF08719.11 ETS76824.1 - 4e-22 79.2 3.3 2.9e-15 56.9 0.4 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF1768) Presenilin PF01080.17 ETS76824.1 - 2.3 6.9 3.3 2.9 6.6 3.3 1.1 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 ETS76824.1 - 3.5 4.6 3.9 4.4 4.3 3.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 ETS76824.1 - 5.3 5.2 9.3 7.7 4.7 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Cu-oxidase_2 PF07731.14 ETS76826.1 - 1.4e-39 134.9 1.4 1.4e-39 134.9 1.4 2.5 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 ETS76826.1 - 4.6e-36 123.4 1.9 4.6e-36 123.4 1.9 3.0 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 ETS76826.1 - 5.5e-35 120.8 0.3 2e-34 119.0 0.1 2.0 2 0 0 2 2 2 1 Multicopper oxidase GMC_oxred_N PF00732.19 ETS76828.1 - 6.4e-68 229.3 0.0 6.1e-67 226.1 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS76828.1 - 1.6e-28 100.1 0.0 2.7e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 ETS76828.1 - 2.3e-06 27.4 0.8 8.7e-06 25.5 0.8 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ETS76828.1 - 6e-05 22.3 0.9 6e-05 22.3 0.9 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ETS76828.1 - 0.00011 21.5 1.5 0.004 16.3 1.2 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 ETS76828.1 - 0.00045 20.4 0.9 0.0018 18.5 0.3 2.3 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS76828.1 - 0.00072 18.9 0.4 0.34 10.1 1.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS76828.1 - 0.011 15.0 0.1 0.022 14.0 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 ETS76828.1 - 0.044 13.0 0.5 0.22 10.7 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS76828.1 - 0.092 11.4 0.3 0.16 10.7 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Transp_cyt_pur PF02133.15 ETS76829.1 - 1.1e-20 73.8 36.4 2.1e-20 72.9 36.4 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PAP2_3 PF14378.6 ETS76830.1 - 1e-31 110.1 16.9 2e-16 60.3 0.3 3.4 2 1 1 3 3 3 3 PAP2 superfamily PAP2 PF01569.21 ETS76830.1 - 0.0055 16.5 2.1 0.0055 16.5 2.1 3.0 2 1 1 3 3 3 1 PAP2 superfamily CX9C PF16860.5 ETS76832.1 - 0.48 10.5 42.5 3.2 7.8 3.4 6.3 4 2 0 5 5 5 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pmp3 PF01679.17 ETS76834.1 - 4.1e-20 71.7 8.9 5.1e-20 71.4 8.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator zf-RanBP PF00641.18 ETS76835.1 - 2.7e-18 65.0 13.3 8.9e-11 40.9 1.6 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 ETS76835.1 - 3.5e-08 33.2 0.0 6.5e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 ETS76835.1 - 2e-06 28.5 0.0 3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease CAF1C_H4-bd PF12265.8 ETS76837.1 - 1.1e-27 96.1 0.3 9.3e-27 93.1 0.1 2.7 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 ETS76837.1 - 6.8e-26 90.0 7.1 2.6e-05 24.9 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS76837.1 - 3.6e-10 40.0 0.1 0.0074 16.6 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain XRN_M PF17846.1 ETS76838.1 - 4.4e-100 335.7 2.6 6.8e-100 335.1 2.6 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 ETS76838.1 - 2.9e-98 328.1 0.0 4.9e-98 327.4 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 ETS76838.1 - 8.4e-77 257.3 0.0 1.6e-76 256.4 0.0 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 ETS76838.1 - 1.1e-25 89.4 0.5 2.3e-25 88.5 0.5 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 ETS76838.1 - 8.9e-18 64.3 0.0 6.3e-11 42.3 0.0 3.7 2 1 1 3 3 3 3 Exoribonuclease Xrn1 D2/D3 domain Xrn1_D3 PF18194.1 ETS76838.1 - 0.0002 21.4 0.0 0.00054 20.0 0.0 1.8 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 Dioxygenase_C PF00775.21 ETS76839.1 - 8.6e-07 28.6 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase DIOX_N PF14226.6 ETS76840.1 - 2.1e-15 57.5 0.0 3.6e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS76840.1 - 4.1e-12 46.5 0.0 7.9e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Strep_his_triad PF04270.13 ETS76840.1 - 0.15 12.1 0.3 0.41 10.7 0.3 1.7 1 0 0 1 1 1 0 Streptococcal histidine triad protein MFS_1 PF07690.16 ETS76841.1 - 4.4e-08 32.4 6.0 5.7e-08 32.1 6.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 ETS76842.1 - 1.4e-21 76.8 17.8 1.5e-20 73.4 16.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS76842.1 - 0.0018 17.2 11.8 0.0063 15.4 5.7 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter LapA_dom PF06305.11 ETS76842.1 - 0.014 15.2 1.4 0.15 11.9 0.0 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Phage_holin_2_4 PF16082.5 ETS76842.1 - 0.088 12.6 0.6 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Ribonucleas_3_3 PF14622.6 ETS76844.1 - 1.3e-23 83.5 0.0 3.7e-23 82.1 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease-III-like HAT_KAT11 PF08214.11 ETS76845.1 - 1.5e-87 294.1 0.0 2.2e-87 293.6 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein 2-Hacid_dh_C PF02826.19 ETS76846.1 - 5.1e-38 130.2 0.0 6.7e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS76846.1 - 1.8e-10 40.6 0.0 2.3e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ETS76846.1 - 5.2e-07 30.0 0.0 9.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ETS76846.1 - 0.00027 21.4 0.0 0.00062 20.3 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 ETS76846.1 - 0.014 16.2 0.0 0.043 14.7 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 ETS76846.1 - 0.092 13.4 0.0 2.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Ank_2 PF12796.7 ETS76847.1 - 4.5e-27 94.4 0.0 4.7e-14 52.7 0.0 4.3 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS76847.1 - 8.9e-17 61.2 0.1 6.9e-06 26.5 0.0 6.1 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS76847.1 - 1.4e-15 57.2 0.6 0.011 16.0 0.0 7.1 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 ETS76847.1 - 2.9e-15 55.9 0.0 5.4e-05 23.5 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 ETS76847.1 - 4.3e-14 51.2 0.2 0.0024 18.2 0.0 7.0 7 0 0 7 7 7 3 Ankyrin repeat HpcH_HpaI PF03328.14 ETS76848.1 - 2.4e-20 72.6 0.0 3.5e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Zn_clus PF00172.18 ETS76850.1 - 8.2e-17 61.1 20.3 5.7e-09 36.0 8.2 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS76850.1 - 9.7e-06 24.8 0.1 1.6e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain GFO_IDH_MocA PF01408.22 ETS76851.1 - 3.2e-27 95.7 0.3 5.2e-27 95.1 0.3 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ETS76851.1 - 5.1e-06 26.5 0.0 1.2e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 ETS76851.1 - 0.00019 22.0 0.2 0.00054 20.5 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CoA_binding PF02629.19 ETS76851.1 - 0.022 15.4 0.0 0.065 13.9 0.0 1.8 1 0 0 1 1 1 0 CoA binding domain NAD_binding_3 PF03447.16 ETS76851.1 - 0.029 15.0 0.1 0.05 14.3 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ETS76851.1 - 0.038 14.1 0.0 0.085 13.0 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AA_permease PF00324.21 ETS76852.1 - 1.1e-106 357.4 38.3 1.3e-106 357.1 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS76852.1 - 1.5e-29 103.1 41.5 1.7e-29 102.9 41.5 1.0 1 0 0 1 1 1 1 Amino acid permease NCE101 PF11654.8 ETS76852.1 - 0.077 12.7 0.2 1.3 8.8 0.1 2.6 2 0 0 2 2 2 0 Non-classical export protein 1 COesterase PF00135.28 ETS76853.1 - 1e-74 252.3 0.0 1.5e-74 251.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS76853.1 - 1.3e-11 44.7 0.2 4.6e-11 43.0 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS76853.1 - 0.048 13.1 0.4 0.082 12.4 0.4 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Mito_carr PF00153.27 ETS76854.1 - 2.5e-21 75.4 4.2 1.7e-08 34.3 0.3 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein RskA PF10099.9 ETS76854.1 - 0.024 15.0 2.8 0.64 10.3 0.9 2.6 2 1 0 2 2 2 0 Anti-sigma-K factor rskA PSDC PF12588.8 ETS76856.1 - 2.7e-56 189.5 0.0 4.2e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 ETS76856.1 - 4.1e-37 127.7 0.0 9.6e-37 126.5 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase PTS_EIIA_1 PF00358.20 ETS76856.1 - 0.027 14.2 0.2 0.057 13.2 0.2 1.5 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Glyco_hydro_6 PF01341.17 ETS76857.1 - 1.8e-107 359.6 2.7 2.5e-107 359.1 2.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 ETS76857.1 - 2.2e-11 43.5 11.7 7.1e-11 41.9 11.7 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Adap_comp_sub PF00928.21 ETS76858.1 - 5.4e-85 285.0 0.0 6.6e-85 284.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ETS76858.1 - 2.7e-05 24.1 0.1 4.9e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HD PF01966.22 ETS76859.1 - 3.5e-05 24.0 0.0 6.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 HD domain FAD_binding_4 PF01565.23 ETS76860.1 - 3.9e-25 88.2 2.0 6.5e-25 87.5 2.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS76860.1 - 7e-10 38.9 0.1 1.3e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Aldolase_II PF00596.21 ETS76861.1 - 1.5e-45 155.4 0.4 2e-45 155.0 0.4 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Glyco_hydro_61 PF03443.14 ETS76862.1 - 8.9e-64 215.2 0.3 1.1e-63 214.9 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fasciclin PF02469.22 ETS76863.1 - 8.1e-48 161.9 5.2 9.9e-24 84.0 1.4 2.1 2 0 0 2 2 2 2 Fasciclin domain Pyrid_ox_like PF16242.5 ETS76864.1 - 5.1e-25 87.8 0.0 7.2e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 ETS76864.1 - 9.9e-12 44.9 0.0 1.9e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase AA_permease PF00324.21 ETS76865.1 - 5.2e-100 335.3 36.6 6.6e-100 335.0 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS76865.1 - 5.3e-23 81.5 38.2 6.9e-23 81.2 38.2 1.1 1 0 0 1 1 1 1 Amino acid permease DCP1 PF06058.13 ETS76866.1 - 2.8e-24 85.3 0.0 4.3e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family RIF5_SNase_1 PF18187.1 ETS76866.1 - 0.034 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 TbRIF5 SNase domain 1 Exo_endo_phos PF03372.23 ETS76867.1 - 0.00023 20.8 0.0 0.0007 19.2 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4232 PF14016.6 ETS76867.1 - 0.018 15.2 0.0 0.072 13.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4232) Ammonium_transp PF00909.21 ETS76868.1 - 3.3e-120 401.4 28.6 3.8e-120 401.2 28.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 ETS76868.1 - 0.14 12.2 5.8 0.63 10.1 0.8 2.9 2 0 0 2 2 2 0 Bacteriophage P21 holin S OPT PF03169.15 ETS76869.1 - 3.5e-96 323.2 39.1 4.2e-96 323.0 39.1 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GFA PF04828.14 ETS76871.1 - 0.00091 19.5 17.1 0.0045 17.3 0.0 3.5 4 1 0 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme C1_2 PF03107.16 ETS76871.1 - 0.16 12.4 6.8 21 5.5 0.1 4.2 4 0 0 4 4 4 0 C1 domain Transp_cyt_pur PF02133.15 ETS76872.1 - 8e-98 328.1 35.1 9.2e-98 327.9 35.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.6 ETS76873.1 - 7.8e-30 104.0 0.1 1.4e-29 103.2 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS76873.1 - 1.6e-16 60.6 0.0 3e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lipase_GDSL_2 PF13472.6 ETS76875.1 - 3.1e-07 31.0 0.0 5.7e-06 26.8 0.0 2.0 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS76875.1 - 0.015 15.3 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Cyclin_C_2 PF16899.5 ETS76876.1 - 1.4e-32 112.2 0.2 1.6e-30 105.6 0.0 2.7 3 0 0 3 3 3 1 Cyclin C-terminal domain Cyclin_N PF00134.23 ETS76876.1 - 0.0053 16.5 0.1 0.0086 15.8 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ETS76876.1 - 0.085 12.9 0.0 10 6.2 0.0 2.4 2 0 0 2 2 2 0 Cyclin, C-terminal domain p450 PF00067.22 ETS76877.1 - 1e-71 242.1 0.0 1.2e-71 241.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 ETS76878.1 - 8.5e-08 32.0 0.1 2e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS76878.1 - 0.00027 20.7 0.0 0.00071 19.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain Mannosyl_trans3 PF11051.8 ETS76879.1 - 1.2e-54 185.5 0.0 4.7e-33 114.7 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative CFEM PF05730.11 ETS76880.1 - 9.4e-11 41.6 12.2 2.3e-10 40.4 12.2 1.7 1 0 0 1 1 1 1 CFEM domain DUF89 PF01937.19 ETS76881.1 - 5.6e-137 456.4 0.0 6.4e-137 456.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF148 PF02520.17 ETS76881.1 - 0.15 12.1 0.9 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 Formyl_trans_N PF00551.19 ETS76882.1 - 5.2e-36 124.1 0.4 9.4e-36 123.2 0.1 1.6 2 0 0 2 2 2 1 Formyl transferase ACT PF01842.25 ETS76882.1 - 6.4e-10 38.6 0.0 1.6e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 ETS76882.1 - 1e-05 25.4 0.0 3.7e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 ACT domain Glyco_trans_4_2 PF13477.6 ETS76882.1 - 0.13 12.2 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like Glyco_hydro_72 PF03198.14 ETS76883.1 - 3.8e-122 407.5 6.9 5e-122 407.1 6.9 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 ETS76883.1 - 5e-19 68.8 5.3 1.8e-18 67.0 5.3 2.0 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 ETS76883.1 - 0.027 13.6 0.0 0.11 11.6 0.0 2.1 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain CFC PF09443.10 ETS76883.1 - 0.18 11.7 0.6 0.36 10.7 0.1 1.7 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) Chorion_2 PF03964.15 ETS76884.1 - 0.0096 16.7 11.6 0.013 16.3 11.6 1.1 1 0 0 1 1 1 1 Chorion family 2 CDK2AP PF09806.9 ETS76884.1 - 0.38 10.8 7.9 0.48 10.5 7.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Herpes_capsid PF06112.11 ETS76884.1 - 2.2 8.3 18.0 3.4 7.7 18.0 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SR-25 PF10500.9 ETS76884.1 - 8.7 5.9 15.6 11 5.5 15.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AcetylCoA_hydro PF02550.15 ETS76885.1 - 0.051 13.6 0.1 0.055 13.4 0.1 1.1 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain TPR_2 PF07719.17 ETS76886.1 - 1.9e-09 36.9 5.5 4.5e-05 23.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 ETS76886.1 - 1.8e-06 27.5 1.8 0.018 14.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS76886.1 - 1.1e-05 25.8 0.1 8.3e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ETS76886.1 - 7.4e-05 23.0 1.5 0.013 15.8 0.5 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 ETS76886.1 - 0.00029 20.8 1.5 0.077 13.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 ETS76886.1 - 0.00056 20.5 1.7 0.00056 20.5 1.7 2.7 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 ETS76886.1 - 0.0014 19.1 0.7 0.31 11.8 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.12 ETS76886.1 - 0.0018 18.2 0.0 0.2 11.7 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ETS76886.1 - 0.0038 17.9 0.3 0.0038 17.9 0.3 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS76886.1 - 0.015 14.7 0.2 0.025 13.9 0.1 1.4 1 1 0 1 1 1 0 MalT-like TPR region TPR_11 PF13414.6 ETS76886.1 - 0.02 14.6 1.4 2.9 7.6 0.3 3.2 3 0 0 3 3 3 0 TPR repeat HCR PF07111.12 ETS76886.1 - 0.024 12.7 0.0 0.044 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) SPO22 PF08631.10 ETS76886.1 - 0.025 14.1 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_4 PF07721.14 ETS76886.1 - 0.19 12.4 0.7 0.19 12.4 0.7 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TauD PF02668.16 ETS76887.1 - 4.2e-27 95.6 0.0 5.8e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 ETS76887.1 - 0.0019 17.4 0.1 0.0034 16.5 0.1 1.3 1 0 0 1 1 1 1 CsiD Acyltransferase PF01553.21 ETS76889.1 - 3.9e-26 91.3 0.0 5.5e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 ETS76889.1 - 5.2e-14 52.1 0.2 9.2e-14 51.3 0.2 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus LIDHydrolase PF10230.9 ETS76890.1 - 8.6e-57 192.7 0.0 1e-56 192.5 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 ETS76890.1 - 2.6e-07 31.5 0.7 3.3e-07 31.1 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS76890.1 - 3e-06 26.7 0.1 5.4e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS76890.1 - 0.00017 21.4 0.1 0.00025 20.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 ETS76890.1 - 0.0011 18.9 0.0 0.002 18.0 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold GFO_IDH_MocA PF01408.22 ETS76891.1 - 1e-23 84.4 0.0 1.6e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ETS76891.1 - 6.3e-13 48.7 0.0 1.1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 ETS76891.1 - 0.0065 17.1 0.0 0.011 16.3 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NAD_kinase PF01513.21 ETS76892.1 - 3.1e-48 164.5 0.0 1.1e-47 162.6 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase Dynamin_N PF00350.23 ETS76893.1 - 2.6e-31 108.9 0.0 6.1e-31 107.7 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 ETS76893.1 - 3.8e-25 88.7 0.4 8e-25 87.6 0.4 1.5 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 ETS76893.1 - 1.1e-05 25.4 0.0 4.7e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 ETS76893.1 - 0.065 13.5 0.2 0.4 10.9 0.0 2.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ENTH PF01417.20 ETS76893.1 - 0.12 12.5 0.3 2.7 8.1 0.1 2.7 2 0 0 2 2 2 0 ENTH domain Uds1 PF15456.6 ETS76893.1 - 4.8 7.3 11.8 0.53 10.4 2.0 3.3 2 1 1 3 3 3 0 Up-regulated During Septation FA_hydroxylase PF04116.13 ETS76895.1 - 2.6e-25 89.3 25.2 1.4e-24 87.0 21.8 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Abhydrolase_9_N PF15420.6 ETS76897.1 - 0.022 14.8 2.6 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus YGGT PF02325.17 ETS76897.1 - 0.086 13.3 1.8 0.35 11.3 1.8 2.0 1 0 0 1 1 1 0 YGGT family SnoaL_4 PF13577.6 ETS76898.1 - 2.9e-09 37.1 0.0 3.3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.16 ETS76899.1 - 2.2e-37 128.8 25.2 2.8e-37 128.5 25.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SpoVAB PF13782.6 ETS76899.1 - 0.063 13.6 1.8 0.22 11.8 1.8 2.0 1 0 0 1 1 1 0 Stage V sporulation protein AB DUF2243 PF10002.9 ETS76899.1 - 0.95 9.6 0.0 0.95 9.6 0.0 2.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2243) DUF1932 PF09130.11 ETS76900.1 - 4.5e-17 61.8 0.0 1.4e-16 60.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 ETS76900.1 - 1.1e-07 32.2 0.0 1.7e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ETS76900.1 - 9e-06 26.2 0.0 1.7e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 ETS76900.1 - 0.00038 20.4 0.0 0.00064 19.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.17 ETS76900.1 - 0.00084 18.4 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase 2-Hacid_dh_C PF02826.19 ETS76900.1 - 0.0021 17.4 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ETS76900.1 - 0.0076 15.8 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 ETS76900.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fe-ADH PF00465.19 ETS76901.1 - 2.2e-64 217.5 0.0 2.8e-64 217.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ETS76901.1 - 3.7e-08 33.4 0.1 0.00021 21.1 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase TraH_2 PF06871.11 ETS76901.1 - 0.05 13.2 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 TraH_2 Amino_oxidase PF01593.24 ETS76902.1 - 4.9e-65 220.6 0.0 5.9e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.21 ETS76902.1 - 3.9e-15 55.9 0.0 7.7e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.6 ETS76902.1 - 1.6e-12 47.5 0.1 3.9e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS76902.1 - 5.4e-09 35.6 0.6 8.4e-09 35.0 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ETS76902.1 - 8.3e-07 28.5 0.4 1.5e-06 27.6 0.4 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 ETS76902.1 - 1.8e-06 27.8 0.1 6e-06 26.1 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ETS76902.1 - 6.1e-06 25.8 0.8 8.5e-06 25.4 0.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ETS76902.1 - 2.6e-05 23.4 0.5 0.001 18.2 0.5 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 ETS76902.1 - 3.9e-05 23.1 0.2 6.5e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ETS76902.1 - 8.8e-05 21.4 0.2 0.00015 20.6 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 ETS76902.1 - 0.00014 21.2 0.6 0.0016 17.7 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS76902.1 - 0.0016 17.6 0.4 0.0037 16.4 0.4 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ETS76902.1 - 0.0059 15.9 0.3 0.037 13.3 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ETS76902.1 - 0.019 14.3 0.2 0.019 14.3 0.2 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 ETS76902.1 - 0.046 13.7 0.5 3.2 7.7 0.1 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 ETS76902.1 - 0.092 13.3 0.6 0.24 12.0 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 ETS76903.1 - 9.9e-20 71.0 0.0 1.6e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS76903.1 - 5.7e-16 58.3 0.0 9.4e-16 57.6 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ETS76903.1 - 3.1e-10 40.2 0.0 4.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ETS76903.1 - 7.5e-10 38.7 0.0 3.8e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ETS76903.1 - 1e-09 38.0 0.0 2.3e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ETS76903.1 - 1.7e-05 24.1 0.1 2.5e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 ETS76903.1 - 9.9e-05 22.3 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 ETS76903.1 - 0.0018 18.8 0.0 0.0045 17.5 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 ETS76903.1 - 0.0023 17.4 0.0 0.0045 16.5 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 ETS76903.1 - 0.0043 16.2 0.0 0.0072 15.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 ETS76903.1 - 0.026 14.1 0.1 0.043 13.4 0.1 1.5 1 1 0 1 1 1 0 NmrA-like family adh_short_C2 PF13561.6 ETS76903.1 - 0.091 12.3 0.1 0.26 10.8 0.1 1.7 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 ETS76903.1 - 0.13 12.5 0.1 0.22 11.8 0.1 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AA_permease PF00324.21 ETS76904.1 - 2.2e-103 346.4 44.4 2.8e-103 346.1 44.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS76904.1 - 2.8e-26 92.3 48.1 3.4e-26 92.0 48.1 1.1 1 0 0 1 1 1 1 Amino acid permease ApbA PF02558.16 ETS76905.1 - 3.9e-27 94.7 0.1 5.2e-27 94.3 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 ETS76905.1 - 3e-25 88.8 0.0 5e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal FAD_binding_3 PF01494.19 ETS76905.1 - 0.12 11.6 0.2 0.21 10.8 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 ETS76905.1 - 0.14 11.7 0.4 0.42 10.1 0.6 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fungal_trans_2 PF11951.8 ETS76906.1 - 2.5e-47 161.5 1.7 3.4e-47 161.1 1.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldolase_II PF00596.21 ETS76907.1 - 5.1e-48 163.5 0.1 6.3e-48 163.2 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain FMN_dh PF01070.18 ETS76908.1 - 4.2e-116 387.8 0.0 4.8e-116 387.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ETS76908.1 - 3.8e-06 26.1 0.7 1e-05 24.7 0.6 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ETS76908.1 - 7.3e-05 22.1 0.2 0.00014 21.1 0.1 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 ETS76908.1 - 0.00097 18.7 0.3 0.05 13.1 0.0 2.7 2 1 1 3 3 3 1 Histidine biosynthesis protein ThiG PF05690.14 ETS76908.1 - 0.0098 15.2 0.3 0.37 10.1 0.0 2.8 2 1 1 3 3 3 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 ETS76908.1 - 0.022 14.0 0.1 0.049 12.8 0.1 1.4 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase NMO PF03060.15 ETS76908.1 - 0.19 11.1 1.1 0.29 10.5 1.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Ank_2 PF12796.7 ETS76909.1 - 5.5e-81 267.2 0.0 3.7e-19 69.1 0.0 7.3 4 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS76909.1 - 2.2e-62 206.7 0.5 4.5e-10 39.8 0.0 10.5 3 2 7 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS76909.1 - 6.7e-56 179.7 0.1 0.00015 21.9 0.0 14.4 16 0 0 16 16 16 12 Ankyrin repeat Ank PF00023.30 ETS76909.1 - 9.9e-52 171.2 2.4 0.00055 20.3 0.0 14.7 15 0 0 15 15 15 10 Ankyrin repeat Ank_5 PF13857.6 ETS76909.1 - 4.3e-42 141.6 5.1 8.7e-06 25.9 0.0 10.4 4 4 6 10 10 10 8 Ankyrin repeats (many copies) VWA_3_C PF18571.1 ETS76909.1 - 0.071 13.0 4.0 68 3.4 0.0 5.2 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain HNH_repeat PF18780.1 ETS76909.1 - 0.25 11.2 2.1 7 6.6 0.0 3.5 4 0 0 4 4 4 0 Homing endonuclease repeat GST_C PF00043.25 ETS76910.1 - 2.4e-08 34.1 0.0 5.6e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ETS76910.1 - 2.7e-08 33.7 0.0 7.1e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ETS76910.1 - 3e-06 27.5 0.0 4.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ETS76910.1 - 8.2e-06 26.0 0.0 2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ETS76910.1 - 3.4e-05 23.9 0.0 0.0001 22.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ETS76910.1 - 6.5e-05 23.2 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 ETS76910.1 - 0.0048 16.7 0.0 0.0081 15.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 ETS76910.1 - 0.0082 16.4 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 ETS76910.1 - 0.16 12.7 0.0 0.26 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain 3Beta_HSD PF01073.19 ETS76911.1 - 9.4e-46 156.0 0.0 1.3e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ETS76911.1 - 1.8e-18 66.9 0.0 2.7e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ETS76911.1 - 2.2e-11 43.4 0.0 4.3e-11 42.4 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ETS76911.1 - 4.8e-11 42.3 0.1 1.2e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 ETS76911.1 - 9.6e-11 41.6 0.0 2.2e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ETS76911.1 - 2.2e-07 30.3 0.7 1.8e-06 27.3 0.7 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ETS76911.1 - 1.9e-06 27.9 0.0 3.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 ETS76911.1 - 0.00036 20.5 0.1 0.0019 18.1 0.1 2.1 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 ETS76911.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 1 0 1 1 1 0 NmrA-like family Kinesin PF00225.23 ETS76912.1 - 3.8e-93 312.1 0.7 9.2e-93 310.8 0.7 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ETS76912.1 - 2.8e-46 157.2 0.2 8.6e-46 155.6 0.2 1.9 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 ETS76912.1 - 0.00085 19.7 0.0 0.00085 19.7 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain Acyltransferase PF01553.21 ETS76913.1 - 0.034 13.8 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 Acyltransferase ILVD_EDD PF00920.21 ETS76914.1 - 4.6e-212 705.2 0.9 5.3e-212 705.0 0.9 1.0 1 0 0 1 1 1 1 Dehydratase family Fungal_trans PF04082.18 ETS76916.1 - 0.00011 21.3 0.9 0.00021 20.4 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 ETS76917.1 - 1.1e-80 270.1 62.9 2.3e-45 154.6 22.5 3.2 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 ETS76917.1 - 1.3e-34 117.9 12.4 4.2e-33 113.1 0.0 3.8 4 0 0 4 4 3 2 CDR ABC transporter ABC_tran PF00005.27 ETS76917.1 - 1.4e-34 119.5 0.0 1.6e-17 64.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 ETS76917.1 - 1.7e-15 57.4 0.3 1.7e-15 57.4 0.3 2.0 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 ETS76917.1 - 5.9e-07 29.7 0.0 0.017 15.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 ETS76917.1 - 8.9e-07 28.3 36.8 8.9e-05 21.7 11.5 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 ETS76917.1 - 1.4e-06 28.3 0.0 0.00028 20.8 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 ETS76917.1 - 8.6e-06 26.3 0.0 0.0069 16.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS76917.1 - 9.1e-06 26.2 0.0 0.021 15.2 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 ETS76917.1 - 1.3e-05 24.9 0.1 0.0003 20.4 0.1 2.5 2 1 1 3 3 3 1 AAA domain SMC_N PF02463.19 ETS76917.1 - 9.4e-05 22.0 0.0 0.041 13.3 0.0 3.7 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ETS76917.1 - 0.00011 21.9 0.5 0.055 13.2 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ETS76917.1 - 0.0018 18.1 0.0 2.5 7.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 ETS76917.1 - 0.0038 17.0 0.1 0.6 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 ETS76917.1 - 0.017 15.6 0.0 2.5 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ETS76917.1 - 0.021 15.1 0.8 2.1 8.6 0.1 3.2 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 ETS76917.1 - 0.034 14.1 0.4 3.1 7.7 0.1 3.1 3 0 0 3 3 3 0 NACHT domain MMR_HSR1 PF01926.23 ETS76917.1 - 0.049 13.7 0.0 13 6.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase dNK PF01712.19 ETS76917.1 - 0.11 12.3 0.0 17 5.2 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_23 PF13476.6 ETS76917.1 - 0.11 13.0 0.0 0.94 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ETS76917.1 - 0.12 12.8 0.0 33 4.9 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 ETS76917.1 - 0.15 12.3 0.0 5.5 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 ETS76917.1 - 0.18 11.4 0.1 0.31 10.6 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain cobW PF02492.19 ETS76917.1 - 0.21 11.2 0.2 1.5 8.4 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain F-box-like PF12937.7 ETS76918.1 - 4.1e-06 26.6 0.0 1.1e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like Amidohydro_1 PF01979.20 ETS76919.1 - 2.3e-42 145.5 0.9 2.8e-42 145.3 0.9 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS76919.1 - 5e-11 42.7 7.5 1.3e-09 38.1 2.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family OPT PF03169.15 ETS76920.1 - 4.8e-128 428.5 61.3 5.5e-128 428.3 61.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FliG_N PF14842.6 ETS76920.1 - 0.037 14.6 0.3 0.063 13.8 0.3 1.3 1 0 0 1 1 1 0 FliG N-terminal domain Peptidase_S10 PF00450.22 ETS76921.1 - 1.6e-74 251.8 0.0 2.7e-74 251.1 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Eclosion PF04736.12 ETS76921.1 - 0.21 11.3 1.3 0.33 10.7 0.1 1.9 2 0 0 2 2 2 0 Eclosion hormone PDZ_6 PF17820.1 ETS76922.1 - 1.6e-05 24.6 0.1 4.5e-05 23.2 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 ETS76922.1 - 0.00032 21.0 0.0 0.001 19.3 0.0 1.9 2 0 0 2 2 2 1 PDZ domain Peptidase_M61 PF05299.12 ETS76922.1 - 0.00067 20.0 3.9 0.00086 19.7 0.1 2.3 1 1 1 2 2 2 1 M61 glycyl aminopeptidase PDZ_2 PF13180.6 ETS76922.1 - 0.061 13.7 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Peptidase_S10 PF00450.22 ETS76923.1 - 2.9e-94 316.9 0.0 3.5e-94 316.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase ABC_tran PF00005.27 ETS76924.1 - 5.4e-45 153.3 0.0 4.9e-28 98.4 0.2 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS76924.1 - 2.8e-27 96.1 27.3 2.3e-14 53.7 14.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ETS76924.1 - 7.2e-10 38.7 6.0 0.00043 19.8 0.1 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ETS76924.1 - 1.1e-06 29.0 0.7 0.019 15.3 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ETS76924.1 - 4.1e-05 24.0 0.8 0.24 11.8 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 ETS76924.1 - 0.00034 20.4 0.3 1.4 8.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 ETS76924.1 - 0.00067 19.4 5.8 0.06 13.1 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SSE PF00437.20 ETS76924.1 - 0.0057 15.8 2.1 0.17 10.9 0.0 2.7 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_7 PF12775.7 ETS76924.1 - 0.01 15.3 0.3 1.5 8.3 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 ETS76924.1 - 0.025 14.5 0.1 0.58 10.0 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase DUF815 PF05673.13 ETS76924.1 - 0.043 13.0 0.1 0.25 10.5 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 ETS76924.1 - 0.056 13.9 0.1 3.4 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 ETS76924.1 - 0.072 12.9 4.7 1.9 8.2 0.2 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_21 PF13304.6 ETS76924.1 - 0.077 12.8 1.1 51 3.5 0.0 3.8 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 ETS76924.1 - 0.09 12.0 1.2 5.1 6.3 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 ETS76924.1 - 0.1 12.2 2.6 7.4 6.1 0.2 2.7 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ETS76924.1 - 0.13 12.2 4.0 8.5 6.3 0.1 3.2 3 0 0 3 3 3 0 NTPase MMR_HSR1 PF01926.23 ETS76924.1 - 0.14 12.2 1.1 0.67 10.1 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 ETS76924.1 - 0.21 11.0 1.3 2.8 7.3 0.2 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 ETS76924.1 - 0.21 12.0 0.8 11 6.4 0.0 3.0 3 0 0 3 3 2 0 RNA helicase DUF87 PF01935.17 ETS76924.1 - 0.26 11.3 0.1 0.26 11.3 0.1 2.5 3 0 0 3 3 3 0 Helicase HerA, central domain DEAD PF00270.29 ETS76924.1 - 0.48 10.2 2.2 5.6 6.7 0.9 2.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_33 PF13671.6 ETS76924.1 - 0.49 10.5 1.3 24 5.1 0.4 2.9 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 ETS76924.1 - 0.56 10.1 7.2 3.1 7.7 0.2 3.0 3 0 0 3 3 2 0 NACHT domain AAA PF00004.29 ETS76924.1 - 0.72 10.3 4.9 13 6.2 0.5 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ETS76924.1 - 0.78 9.7 2.4 15 5.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ETS76924.1 - 7.1 7.2 5.3 8.1 7.0 1.3 2.7 2 1 0 2 2 2 0 AAA domain Amidase PF01425.21 ETS76926.1 - 6.2e-61 206.7 0.7 3.2e-59 201.1 0.5 2.1 2 0 0 2 2 2 2 Amidase EI24 PF07264.11 ETS76927.1 - 0.00048 20.4 0.8 0.65 10.2 0.2 2.6 2 1 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) DUF4271 PF14093.6 ETS76927.1 - 0.36 10.7 0.0 0.36 10.7 0.0 2.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4271) DUF21 PF01595.20 ETS76928.1 - 0.02 14.6 6.5 0.055 13.2 6.5 1.7 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain TRAM_LAG1_CLN8 PF03798.16 ETS76928.1 - 9.3 5.9 17.4 3.1 7.5 10.5 2.6 3 0 0 3 3 3 0 TLC domain Fungal_trans_2 PF11951.8 ETS76930.1 - 7.8e-35 120.4 1.0 1.2e-34 119.8 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ala_racemase_N PF01168.20 ETS76930.1 - 2.1e-14 53.7 0.1 3.7e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 ETS76930.1 - 2.2e-12 47.4 0.0 5.7e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Zn_clus PF00172.18 ETS76930.1 - 0.016 15.3 2.1 0.039 14.1 2.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Gln-synt_C PF00120.24 ETS76931.1 - 7.3e-76 255.4 0.0 9.5e-76 255.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 ETS76931.1 - 0.0012 18.7 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain Aldedh PF00171.22 ETS76932.1 - 7.5e-129 430.2 0.0 8.4e-129 430.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ETS76932.1 - 0.00056 19.1 0.0 0.0011 18.1 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) adh_short_C2 PF13561.6 ETS76933.1 - 4.8e-57 193.2 0.7 5.5e-57 193.0 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS76933.1 - 7e-41 139.8 1.0 8.4e-41 139.6 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS76933.1 - 2.7e-08 33.9 1.5 4e-08 33.4 1.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ETS76933.1 - 0.012 15.4 0.5 0.025 14.5 0.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ChuX_HutX PF06228.13 ETS76933.1 - 0.014 15.2 0.0 1.2 8.9 0.0 2.3 1 1 0 2 2 2 0 Haem utilisation ChuX/HutX Glyoxalase PF00903.25 ETS76934.1 - 5.7e-10 39.5 0.0 1.4e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ETS76934.1 - 0.00012 22.3 0.0 0.00026 21.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Tannase PF07519.11 ETS76935.1 - 1.2e-82 278.3 0.0 1e-80 271.9 0.0 2.0 1 1 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 ETS76935.1 - 4.2e-05 23.1 0.1 0.21 11.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ETS76935.1 - 0.0021 17.8 0.4 0.017 14.8 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS76935.1 - 0.015 14.6 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Tyrosinase PF00264.20 ETS76937.1 - 6.8e-37 127.9 10.1 1.5e-36 126.7 10.1 1.6 1 1 0 1 1 1 1 Common central domain of tyrosinase Sugar_tr PF00083.24 ETS76938.1 - 1.4e-69 235.2 21.8 1.7e-69 234.8 21.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS76938.1 - 1.1e-14 54.2 38.5 2e-11 43.4 20.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 ETS76939.1 - 5.5e-65 219.9 0.0 7.4e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 ETS76940.1 - 2.7e-08 33.2 2.0 6.1e-08 32.0 2.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 ETS76940.1 - 5.9e-08 32.9 7.6 5.8e-05 23.6 1.2 3.6 2 0 0 2 2 2 2 C2H2-type zinc finger Zn_clus PF00172.18 ETS76940.1 - 2.1e-05 24.6 10.4 2.1e-05 24.6 10.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 ETS76940.1 - 5.3e-05 23.4 8.5 0.00075 19.8 1.7 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ETS76940.1 - 0.0016 18.8 1.9 0.023 15.1 0.8 3.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ETS76940.1 - 0.0034 17.3 3.4 0.0047 16.9 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger adh_short PF00106.25 ETS76941.1 - 2.3e-28 99.0 0.0 3e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS76941.1 - 1.5e-20 73.7 0.0 7.5e-20 71.5 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS76941.1 - 3.8e-09 36.7 0.1 5e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS76941.1 - 0.065 12.4 0.1 0.099 11.8 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PhyH PF05721.13 ETS76944.1 - 6.6e-17 62.5 0.0 8.7e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.8 ETS76945.1 - 4.9e-08 32.2 0.9 1.1e-07 31.0 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain TENA_THI-4 PF03070.16 ETS76946.1 - 2.9e-10 40.3 0.0 2.6e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 TENA/THI-4/PQQC family DNA_primase_lrg PF04104.14 ETS76947.1 - 1.5e-84 283.6 0.0 3.1e-84 282.5 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit HMG_box_2 PF09011.10 ETS76947.1 - 0.033 14.8 1.0 0.079 13.6 1.0 1.5 1 0 0 1 1 1 0 HMG-box domain Sec16_C PF12931.7 ETS76948.1 - 1.8e-108 362.7 0.3 2.5e-108 362.3 0.3 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 ETS76948.1 - 1.3e-35 122.5 0.0 4.5e-35 120.8 0.0 2.0 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Cytomega_UL20A PF05984.12 ETS76948.1 - 0.27 11.6 2.0 12 6.3 0.2 3.2 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein DUF5427 PF10310.9 ETS76948.1 - 0.56 9.1 6.8 1.9 7.3 6.8 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PAN_3 PF08277.12 ETS76949.1 - 0.81 9.5 4.0 1.8 8.4 2.8 2.2 1 1 1 2 2 2 0 PAN-like domain ketoacyl-synt PF00109.26 ETS76950.1 - 1.8e-72 243.9 0.0 3.9e-72 242.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 ETS76950.1 - 5.2e-40 137.7 0.2 5.4e-39 134.4 0.0 2.5 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 ETS76950.1 - 8.4e-38 130.6 0.0 3.3e-37 128.7 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ETS76950.1 - 7.2e-34 116.3 0.3 2.2e-33 114.8 0.3 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 ETS76950.1 - 3.2e-12 46.3 0.0 5.6e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 ETS76950.1 - 2.9e-09 37.1 0.2 6.9e-09 35.9 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 ETS76950.1 - 8.4e-07 29.4 0.1 3.4e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 ETS76950.1 - 0.0001 21.8 0.1 0.00022 20.7 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_7 PF12715.7 ETS76950.1 - 0.093 12.0 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase family Lactamase_B PF00753.27 ETS76951.1 - 6e-18 65.6 2.4 1.3e-16 61.2 2.4 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS76951.1 - 1.8e-07 30.8 0.2 3.3e-07 30.0 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 ETS76951.1 - 0.00026 20.9 1.2 0.02 14.9 0.0 2.7 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B_3 PF13483.6 ETS76951.1 - 0.0058 16.5 0.0 0.0099 15.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF1772 PF08592.11 ETS76952.1 - 5.6e-30 104.5 7.2 7.9e-30 104.0 7.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF2085 PF09858.9 ETS76952.1 - 0.092 13.2 1.6 6.4 7.3 0.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) Glyco_trans_2_3 PF13632.6 ETS76952.1 - 0.89 9.4 6.2 1.7 8.5 6.2 1.4 1 0 0 1 1 1 0 Glycosyl transferase family group 2 EthD PF07110.11 ETS76953.1 - 5.9e-11 43.4 0.3 6.9e-11 43.1 0.3 1.1 1 0 0 1 1 1 1 EthD domain Cu-oxidase_3 PF07732.15 ETS76954.1 - 1.1e-43 148.1 2.9 3.8e-42 143.1 2.7 2.7 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ETS76954.1 - 6.4e-41 139.3 1.8 1.5e-35 121.9 0.0 3.8 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 ETS76954.1 - 2.7e-30 105.6 1.1 5e-30 104.7 0.1 2.0 2 0 0 2 2 2 1 Multicopper oxidase NAD_binding_10 PF13460.6 ETS76955.1 - 1.8e-14 54.0 0.0 2.1e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding SnoaL_2 PF12680.7 ETS76956.1 - 0.033 14.8 0.0 0.049 14.3 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain Methyltransf_11 PF08241.12 ETS76957.1 - 2.7e-14 53.6 0.0 5e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS76957.1 - 3.4e-11 43.7 0.0 5.5e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS76957.1 - 1.9e-08 34.2 0.0 3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS76957.1 - 1.7e-07 31.9 0.0 2.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS76957.1 - 5.1e-06 26.4 0.0 7.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 ETS76957.1 - 0.0021 17.7 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 ETS76957.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PASTA PF03793.19 ETS76957.1 - 0.18 11.7 0.1 0.74 9.7 0.0 1.9 2 0 0 2 2 2 0 PASTA domain AflR PF08493.10 ETS76959.1 - 2.9e-17 63.1 3.0 5e-17 62.3 3.0 1.3 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 ETS76959.1 - 1.3e-07 31.6 12.7 1.3e-07 31.6 12.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_25 PF13649.6 ETS76960.1 - 6.3e-12 46.0 0.0 2.3e-11 44.2 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS76960.1 - 7.5e-10 39.4 0.0 1.2e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS76960.1 - 5.4e-09 36.6 0.0 1.1e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS76960.1 - 7e-06 25.9 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS76960.1 - 2.2e-05 24.3 0.0 4.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS76960.1 - 6.8e-05 22.3 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ETS76960.1 - 0.027 14.0 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 ETS76960.1 - 0.26 10.2 0.0 0.39 9.7 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Questin_oxidase PF14027.6 ETS76961.1 - 8.3e-84 282.0 0.0 1e-83 281.8 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like Cu-oxidase_3 PF07732.15 ETS76962.1 - 2.6e-43 146.8 6.4 1.6e-42 144.3 0.4 2.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ETS76962.1 - 4.9e-34 117.0 9.4 6.2e-33 113.4 1.9 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 ETS76962.1 - 6.1e-32 110.9 0.1 5.3e-29 101.4 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Pyr_redox_2 PF07992.14 ETS76963.1 - 3.5e-41 141.4 0.0 4.3e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS76963.1 - 2.6e-13 50.3 0.4 8.2e-08 32.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS76963.1 - 3.1e-08 33.1 0.0 0.00026 20.2 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ETS76963.1 - 6.9e-07 29.2 3.9 0.00043 20.0 0.0 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS76963.1 - 4.3e-06 26.8 0.2 0.0065 16.5 0.0 3.2 3 1 1 4 4 4 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ETS76963.1 - 0.00018 20.9 0.1 0.1 11.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 ETS76963.1 - 0.00064 19.1 0.1 0.041 13.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS76963.1 - 0.00083 18.5 0.0 0.92 8.5 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 ETS76963.1 - 0.0024 18.1 0.7 0.097 12.9 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ETS76963.1 - 0.015 14.6 0.2 1.1 8.4 0.1 2.2 2 0 0 2 2 2 0 Thi4 family Sacchrp_dh_NADP PF03435.18 ETS76963.1 - 0.015 15.5 0.2 4.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_2 PF00890.24 ETS76963.1 - 0.064 12.3 0.4 1.3 8.0 0.0 2.7 2 1 0 3 3 3 0 FAD binding domain NAD_binding_7 PF13241.6 ETS76963.1 - 0.071 13.6 0.1 3.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.18 ETS76963.1 - 0.13 12.6 0.0 8.1 6.7 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.22 ETS76963.1 - 0.19 10.7 2.4 6.8 5.7 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 ETS76963.1 - 0.4 9.5 1.1 2.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 ETS76963.1 - 0.54 8.9 3.1 15 4.2 0.4 3.0 3 1 1 4 4 4 0 HI0933-like protein Fungal_trans_2 PF11951.8 ETS76964.1 - 2.3e-50 171.6 8.5 3.1e-50 171.1 8.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS76964.1 - 1.8e-08 34.3 5.1 4.2e-08 33.2 5.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHC2_SAM_assoc PF16616.5 ETS76964.1 - 0.097 13.5 0.6 0.27 12.1 0.6 1.7 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Trp_halogenase PF04820.14 ETS76965.1 - 9.8e-30 103.8 0.0 1.3e-14 53.9 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 ETS76965.1 - 4.2e-12 46.0 0.0 2.7e-11 43.3 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ETS76965.1 - 4.4e-06 26.8 0.1 1.7e-05 24.9 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS76965.1 - 9.9e-06 25.0 0.0 1.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ETS76965.1 - 3.7e-05 23.3 1.2 5.5e-05 22.7 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS76965.1 - 0.00012 20.9 0.1 0.00022 20.1 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 ETS76965.1 - 0.00021 20.5 0.1 0.00034 19.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 ETS76965.1 - 0.0003 20.0 0.1 0.00049 19.3 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 ETS76965.1 - 0.00079 18.7 0.1 0.0075 15.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 ETS76965.1 - 0.00082 19.0 0.2 0.0016 18.1 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS76965.1 - 0.014 16.0 0.1 0.046 14.3 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS76965.1 - 0.066 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS76965.1 - 0.073 12.1 0.1 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 ETS76965.1 - 0.15 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PIN_8 PF18476.1 ETS76966.1 - 0.014 15.2 0.1 0.057 13.3 0.1 2.0 1 0 0 1 1 1 0 PIN like domain ATPase_2 PF01637.18 ETS76966.1 - 0.21 11.5 2.9 0.63 9.9 0.4 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA PF00004.29 ETS76967.1 - 1.7e-17 64.1 0.0 4.8e-17 62.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS76967.1 - 3.3e-05 24.3 0.2 0.00038 20.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 ETS76967.1 - 0.0067 16.4 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ETS76967.1 - 0.058 14.0 0.0 0.2 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ETS76967.1 - 0.064 13.5 3.1 0.3 11.4 0.2 3.1 3 1 1 4 4 4 0 AAA domain CPT PF07931.12 ETS76967.1 - 0.082 12.7 0.0 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein RuvB_N PF05496.12 ETS76967.1 - 0.19 11.5 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF2721 PF11026.8 ETS76968.1 - 0.0038 17.1 0.5 0.0072 16.2 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) Phage_tail_APC PF16778.5 ETS76968.1 - 0.0048 16.7 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 Phage tail assembly chaperone protein Pkip-1 PF06878.11 ETS76968.1 - 0.015 15.5 0.4 0.033 14.3 0.3 1.6 1 1 0 1 1 1 0 Pkip-1 protein DUF2417 PF10329.9 ETS76968.1 - 0.019 14.4 1.4 0.031 13.7 1.4 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Peptidase_M16 PF00675.20 ETS76969.1 - 4e-31 108.0 4.3 8.7e-31 106.9 0.1 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ETS76969.1 - 5.5e-07 29.8 0.1 1.8e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Synaptobrevin PF00957.21 ETS76969.1 - 0.46 10.3 1.4 1.2 9.0 1.4 1.7 1 0 0 1 1 1 0 Synaptobrevin tRNA-synt_2 PF00152.20 ETS76971.1 - 5.7e-32 111.0 0.0 7.7e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DIOX_N PF14226.6 ETS76972.1 - 0.00027 21.7 0.0 0.00044 21.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS76972.1 - 0.01 16.3 0.0 0.015 15.8 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Haem_oxygenas_2 PF14518.6 ETS76973.1 - 2.6e-36 125.1 0.0 4.9e-36 124.1 0.0 1.5 1 0 0 1 1 1 1 Iron-containing redox enzyme PTP_N PF12453.8 ETS76973.1 - 0.084 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal MFS_1 PF07690.16 ETS76975.1 - 1e-41 143.0 44.9 3.6e-37 128.1 33.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5056 PF16479.5 ETS76975.1 - 0.063 13.5 0.9 0.21 11.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) OATP PF03137.20 ETS76975.1 - 6 5.0 19.7 0.0077 14.6 3.7 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 ETS76976.1 - 2.2e-63 214.6 0.0 3.3e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 ETS76977.1 - 3.3e-22 78.8 0.2 1e-15 57.5 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS76977.1 - 2.9e-06 27.3 10.1 2.9e-06 27.3 10.1 2.2 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MOSC PF03473.17 ETS76978.1 - 3.1e-25 88.7 0.0 5.1e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 ETS76978.1 - 2.2e-13 50.1 0.0 1.6e-12 47.4 0.0 2.2 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain DBR1 PF05011.13 ETS76979.1 - 2.4e-48 164.1 0.6 1.5e-47 161.5 0.2 2.0 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 ETS76979.1 - 1.8e-05 25.4 1.8 3.1e-05 24.6 1.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Aldo_ket_red PF00248.21 ETS76980.1 - 1.4e-62 211.5 0.0 1.7e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HlyIII PF03006.20 ETS76981.1 - 1.8e-37 129.2 12.5 2.3e-37 128.9 12.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related MerC PF03203.14 ETS76981.1 - 0.35 11.3 5.5 0.91 10.0 5.5 1.8 1 1 0 1 1 1 0 MerC mercury resistance protein Sdh_cyt PF01127.22 ETS76981.1 - 1.8 8.6 11.0 0.17 11.9 5.3 2.1 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ank_2 PF12796.7 ETS76982.1 - 1.9e-24 86.0 0.1 9.2e-12 45.4 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS76982.1 - 6.3e-19 67.8 7.8 3.3e-08 33.6 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 ETS76982.1 - 1.1e-17 63.6 1.4 0.0014 19.0 0.0 5.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 ETS76982.1 - 1.3e-17 63.9 3.1 5.3e-09 36.4 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS76982.1 - 1.6e-15 55.6 1.0 0.00016 21.9 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat PNP_UDP_1 PF01048.20 ETS76982.1 - 4.8e-11 42.4 0.0 3.1e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 Phosphorylase superfamily NACHT PF05729.12 ETS76982.1 - 2.7e-09 37.1 0.8 8.4e-09 35.6 0.0 2.3 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 ETS76982.1 - 0.0023 18.4 0.0 0.014 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 ETS76982.1 - 0.018 14.3 0.0 0.038 13.2 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.6 ETS76982.1 - 0.029 14.6 0.0 0.26 11.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF5535 PF17687.1 ETS76982.1 - 0.079 13.1 0.2 2.6 8.2 0.0 3.1 2 1 0 2 2 2 0 Family of unknown function (DUF5535) AAA_5 PF07728.14 ETS76982.1 - 0.091 12.8 0.0 29 4.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) HlyIII PF03006.20 ETS76983.1 - 1.5e-40 139.3 12.9 1.8e-40 139.0 12.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related Peptidase_S8 PF00082.22 ETS76984.1 - 1.1e-22 80.7 0.0 2.3e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.7 ETS76986.1 - 1.4e-53 179.4 4.6 4.1e-16 59.3 0.1 5.5 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS76986.1 - 7.8e-44 147.5 11.4 1.4e-09 38.3 0.2 8.5 4 3 6 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 ETS76986.1 - 1.1e-39 133.2 20.3 1.2e-06 28.7 0.0 11.5 11 1 0 11 11 11 8 Ankyrin repeat Ank_3 PF13606.6 ETS76986.1 - 3.8e-39 128.2 12.1 0.00052 20.3 0.1 12.0 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.6 ETS76986.1 - 1.2e-35 121.0 8.5 6.5e-07 29.5 0.5 7.7 4 2 4 8 8 8 7 Ankyrin repeats (many copies) zf-C2H2_4 PF13894.6 ETS76986.1 - 0.23 12.4 2.3 1.1e+02 4.1 0.1 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3632 PF12311.8 ETS76988.1 - 7.1e-18 65.6 0.0 1.1e-17 65.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) HCO3_cotransp PF00955.21 ETS76991.1 - 3e-88 296.9 8.0 5e-46 157.6 8.1 2.1 1 1 1 2 2 2 2 HCO3- transporter family Sulfate_transp PF00916.20 ETS76991.1 - 0.02 13.7 8.7 0.67 8.6 2.5 2.4 2 0 0 2 2 2 0 Sulfate permease family NOA36 PF06524.12 ETS76991.1 - 7 5.9 5.4 10 5.4 2.4 2.0 2 0 0 2 2 2 0 NOA36 protein Peptidase_M41 PF01434.18 ETS76992.1 - 3e-66 222.9 0.0 7.9e-66 221.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 ETS76992.1 - 1.3e-41 142.1 0.0 3e-41 141.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ETS76992.1 - 1.9e-12 46.8 0.0 5.1e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 ETS76992.1 - 3.7e-12 46.6 0.0 1.1e-11 45.0 0.0 1.9 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 ETS76992.1 - 0.0016 18.5 0.0 0.0061 16.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ETS76992.1 - 0.0044 16.3 0.0 0.0079 15.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 ETS76992.1 - 0.005 16.6 0.0 0.03 14.1 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ETS76992.1 - 0.0083 16.4 0.1 1.5 9.1 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS76992.1 - 0.01 16.2 0.1 0.44 10.9 0.1 2.7 1 1 0 2 2 2 0 AAA ATPase domain AAA_2 PF07724.14 ETS76992.1 - 0.024 14.7 0.0 0.081 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF771 PF05595.11 ETS76992.1 - 0.14 12.1 1.0 6.5 6.8 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF771) IstB_IS21 PF01695.17 ETS76992.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Fungal_trans PF04082.18 ETS76993.1 - 9.7e-24 83.8 0.0 3e-23 82.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS76993.1 - 1.3e-10 41.2 11.3 2.2e-10 40.5 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Folliculin PF11704.8 ETS76993.1 - 0.0086 16.0 0.1 0.0086 16.0 0.1 2.1 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport efThoc1 PF11957.8 ETS76993.1 - 0.62 8.7 3.0 0.2 10.3 0.1 1.6 2 0 0 2 2 2 0 THO complex subunit 1 transcription elongation factor SWI-SNF_Ssr4 PF08549.10 ETS76993.1 - 3.7 6.1 13.3 0.17 10.5 0.8 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) SRP-alpha_N PF04086.13 ETS76993.1 - 4.8 7.0 14.6 0.13 12.2 1.6 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal ATP11 PF06644.11 ETS76993.1 - 5.5 6.7 12.1 0.77 9.5 1.4 2.2 2 0 0 2 2 2 0 ATP11 protein CCDC53 PF10152.9 ETS76993.1 - 8 6.9 13.3 7.7 6.9 1.5 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Amnionless PF14828.6 ETS76994.1 - 0.15 10.9 0.6 0.38 9.5 0.0 1.8 2 0 0 2 2 2 0 Amnionless RIFIN PF02009.16 ETS76994.1 - 0.36 10.7 5.5 0.36 10.7 0.0 2.4 1 1 2 3 3 3 0 Rifin DUF5301 PF17225.3 ETS76995.1 - 0.012 16.0 1.0 0.032 14.6 1.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5300) Peptidase_C37 PF05416.12 ETS76995.1 - 0.09 11.3 6.3 0.11 11.0 6.3 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase IGPD PF00475.18 ETS76996.1 - 1.4e-59 200.6 0.7 1.9e-59 200.1 0.7 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase MARVEL PF01284.23 ETS76997.1 - 0.00014 22.0 18.6 0.0023 18.0 12.0 2.2 1 1 1 2 2 2 2 Membrane-associating domain Orf78 PF06024.12 ETS76997.1 - 0.15 12.4 0.1 1.4 9.3 0.0 2.2 2 0 0 2 2 2 0 Orf78 (ac78) EphA2_TM PF14575.6 ETS76997.1 - 0.15 13.0 0.3 0.84 10.6 0.0 2.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF3422 PF11902.8 ETS76997.1 - 0.53 9.3 3.9 0.54 9.3 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3422) PIG-P PF08510.12 ETS76997.1 - 4.8 7.1 5.9 1.9 8.4 2.7 1.7 1 1 0 1 1 1 0 PIG-P FRB_dom PF08771.11 ETS77000.1 - 0.15 12.5 1.1 1.1 9.7 1.1 2.2 1 1 0 1 1 1 0 FKBP12-rapamycin binding domain DUF2237 PF09996.9 ETS77001.1 - 1.7e-37 127.9 0.0 1.9e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) MFS_1 PF07690.16 ETS77002.1 - 9.4e-46 156.3 23.8 9.4e-46 156.3 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS77002.1 - 1e-15 57.6 16.2 1.1e-15 57.4 9.1 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 ETS77002.1 - 0.00059 19.2 4.8 0.0011 18.3 4.4 1.7 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Adeno_PIX PF03955.14 ETS77002.1 - 0.39 10.9 3.1 0.87 9.8 0.1 2.7 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) CoA_binding PF02629.19 ETS77004.1 - 7.1e-28 97.1 0.9 7.1e-28 97.1 0.9 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 ETS77004.1 - 6.6e-24 84.5 0.3 1e-23 83.8 0.3 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 ETS77004.1 - 2.3e-07 30.7 0.1 4.1e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 ETS77004.1 - 0.00015 22.2 0.0 0.0006 20.3 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain AAA PF00004.29 ETS77005.1 - 5.7e-41 140.0 0.0 1e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 ETS77005.1 - 1.1e-11 44.5 0.2 2.4e-11 43.4 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 ETS77005.1 - 4.7e-11 42.3 0.4 8.6e-11 41.5 0.4 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 ETS77005.1 - 5.1e-06 26.8 0.2 0.006 16.9 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 ETS77005.1 - 7.3e-06 26.2 0.0 1.4e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 ETS77005.1 - 1.1e-05 24.7 0.0 2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 ETS77005.1 - 5.6e-05 23.2 0.1 0.00017 21.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ETS77005.1 - 0.00026 21.4 0.2 0.0027 18.1 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 ETS77005.1 - 0.00032 20.5 0.0 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_OB_N PF17758.1 ETS77005.1 - 0.0012 18.4 0.7 0.0068 16.0 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 ETS77005.1 - 0.0023 18.5 0.0 0.0052 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ETS77005.1 - 0.0024 18.1 0.1 0.0082 16.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 ETS77005.1 - 0.0097 16.1 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ETS77005.1 - 0.017 15.2 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ETS77005.1 - 0.018 14.7 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 ETS77005.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 ETS77005.1 - 0.025 13.8 0.1 0.069 12.4 0.1 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 ETS77005.1 - 0.027 13.8 0.2 0.5 9.7 0.1 2.2 1 1 0 2 2 2 0 KaiC NACHT PF05729.12 ETS77005.1 - 0.03 14.2 0.2 0.63 9.9 0.1 2.4 1 1 0 2 2 2 0 NACHT domain PhoH PF02562.16 ETS77005.1 - 0.047 13.1 1.1 0.5 9.8 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.22 ETS77005.1 - 0.052 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 ETS77005.1 - 0.06 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 ETS77005.1 - 0.063 12.6 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 ETS77005.1 - 0.079 12.5 1.5 0.61 9.6 0.4 2.5 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 ETS77005.1 - 0.1 12.3 1.7 0.32 10.7 0.3 2.3 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 ETS77005.1 - 0.16 11.1 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 ETS77005.1 - 0.21 11.1 0.1 0.51 9.8 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Peptidase_S15 PF02129.18 ETS77006.1 - 7.9e-38 130.6 0.6 9e-35 120.6 0.3 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ETS77006.1 - 9.4e-31 107.5 0.1 8.9e-30 104.3 0.1 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 ETS77006.1 - 0.062 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FAD_binding_3 PF01494.19 ETS77007.1 - 2.5e-33 115.8 0.0 8.6e-33 114.0 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ETS77007.1 - 0.2 10.3 0.1 0.31 9.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 ETS77007.1 - 0.22 10.5 0.1 0.35 9.9 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Polysacc_deac_1 PF01522.21 ETS77008.1 - 9.1e-13 48.2 0.0 1.8e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Dioxygenase_C PF00775.21 ETS77009.1 - 6.5e-40 136.5 0.0 9e-40 136.0 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 ETS77009.1 - 6.8e-29 99.5 0.1 1.2e-28 98.7 0.1 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 ETS77009.1 - 0.055 13.7 0.1 0.21 11.9 0.1 1.9 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 ETS77009.1 - 0.13 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) Fungal_trans PF04082.18 ETS77010.1 - 2.3e-15 56.4 0.6 5.9e-15 55.0 0.2 2.0 2 1 1 3 3 3 1 Fungal specific transcription factor domain zf-CCHC PF00098.23 ETS77011.1 - 5.5e-08 32.5 9.6 2.3e-06 27.4 0.7 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 ETS77011.1 - 0.073 12.8 7.7 1.3 8.8 0.1 2.6 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_6 PF15288.6 ETS77011.1 - 0.096 12.5 3.6 1.5 8.7 0.2 2.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 ETS77011.1 - 0.11 12.4 0.2 0.11 12.4 0.2 2.5 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 ETS77011.1 - 0.49 10.2 5.7 0.17 11.6 0.5 2.3 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 ETS77011.1 - 4.8 7.1 8.9 0.23 11.3 0.9 2.2 2 0 0 2 2 2 0 Zinc knuckle Hus1 PF04005.12 ETS77012.1 - 2e-89 299.6 0.0 2.2e-89 299.4 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein zf-RING_2 PF13639.6 ETS77013.1 - 8.6e-08 32.4 3.2 8.6e-08 32.4 3.2 3.0 2 1 1 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 ETS77013.1 - 1.5e-07 31.3 8.5 0.0026 17.7 0.5 2.8 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 ETS77013.1 - 1.6e-06 27.8 11.0 0.00045 20.0 0.0 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ETS77013.1 - 0.00011 22.4 3.2 0.00011 22.4 3.2 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ETS77013.1 - 0.0016 18.4 0.6 0.0016 18.4 0.6 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ETS77013.1 - 0.01 15.7 1.5 0.01 15.7 1.5 3.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ETS77013.1 - 0.056 13.3 17.9 0.1 12.4 2.7 3.8 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 ETS77013.1 - 0.19 11.9 8.3 0.73 10.1 6.7 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 ETS77013.1 - 0.21 11.8 13.8 0.93 9.7 0.8 3.7 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ETS77013.1 - 1.8 8.5 16.0 0.52 10.2 0.6 3.9 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 RecR PF02132.15 ETS77013.1 - 5.6 6.6 11.2 13 5.4 0.3 3.7 3 0 0 3 3 3 0 RecR protein zf-ANAPC11 PF12861.7 ETS77013.1 - 6.5 6.9 9.4 0.46 10.6 2.5 2.7 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 11 RING-H2 finger FH2 PF02181.23 ETS77014.1 - 4.1e-84 282.8 4.6 4.1e-84 282.8 4.6 1.8 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 ETS77014.1 - 1.3e-63 214.0 0.1 4e-63 212.4 0.1 1.9 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 ETS77014.1 - 4.2e-51 173.4 2.1 7.5e-50 169.3 0.5 2.8 1 1 1 2 2 2 2 Diaphanous FH3 Domain But2 PF09792.9 ETS77015.1 - 0.0045 17.4 0.1 0.012 16.0 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Ring_hydroxyl_A PF00848.19 ETS77016.1 - 1.2e-23 84.3 2.4 9.6e-12 45.3 1.5 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 ETS77016.1 - 6.4e-14 51.7 0.0 1.2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DAO PF01266.24 ETS77017.1 - 1e-30 107.5 0.4 1.6e-30 106.9 0.4 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS77017.1 - 7.9e-06 25.9 0.1 0.0081 16.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ETS77017.1 - 0.00053 20.2 0.1 0.0021 18.2 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ETS77017.1 - 0.0016 17.6 0.2 0.011 14.8 0.0 2.2 2 1 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 ETS77017.1 - 0.022 13.6 0.1 0.21 10.4 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 ETS77017.1 - 0.024 13.9 0.1 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 ETS77017.1 - 0.034 13.5 0.0 4 6.7 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase TrkA_N PF02254.18 ETS77017.1 - 0.059 13.6 0.0 0.093 13.0 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans PF04082.18 ETS77018.1 - 2.7e-08 33.2 0.4 4.5e-08 32.4 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GCV_T PF01571.21 ETS77019.1 - 5.7e-73 245.5 0.0 9.1e-73 244.8 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 ETS77019.1 - 7.9e-44 150.7 1.1 1.4e-43 149.9 1.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 ETS77019.1 - 2.7e-21 75.3 0.2 1e-20 73.4 0.2 2.1 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 ETS77019.1 - 1e-18 67.4 0.1 2.3e-18 66.3 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox_2 PF07992.14 ETS77019.1 - 0.00014 21.2 0.1 0.047 12.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS77019.1 - 0.00021 21.8 0.0 0.012 16.1 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS77019.1 - 0.00083 18.5 0.1 0.0016 17.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 ETS77019.1 - 0.001 19.3 0.0 0.0035 17.6 0.0 1.9 2 0 0 2 2 1 1 TrkA-N domain Trp_halogenase PF04820.14 ETS77019.1 - 0.0018 17.2 0.0 0.044 12.6 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Shikimate_DH PF01488.20 ETS77019.1 - 0.0028 17.7 0.1 0.0054 16.8 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 ETS77019.1 - 0.02 14.9 0.1 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ETS77019.1 - 0.049 13.9 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 ETS77019.1 - 0.15 11.4 0.1 0.29 10.5 0.1 1.4 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.6 ETS77019.1 - 0.18 11.0 0.1 2.2 7.5 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pectate_lyase PF03211.13 ETS77019.1 - 0.24 10.9 0.0 0.4 10.2 0.0 1.2 1 0 0 1 1 1 0 Pectate lyase An_peroxidase PF03098.15 ETS77020.1 - 4.2e-37 127.9 0.1 7.8e-25 87.4 0.1 3.3 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 ETS77020.1 - 1.4e-09 37.2 0.1 6.2e-07 28.5 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF2235 PF09994.9 ETS77021.1 - 8.6e-85 284.6 0.3 1.1e-84 284.2 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 ETS77021.1 - 0.00053 20.0 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Ysc84 PF04366.12 ETS77022.1 - 5.8e-50 168.3 1.7 2.4e-49 166.3 0.0 2.4 3 0 0 3 3 3 1 Las17-binding protein actin regulator LPD22 PF18834.1 ETS77022.1 - 1.3 9.3 4.2 0.31 11.3 0.2 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 zf-C2H2_7 PF15269.6 ETS77023.1 - 0.2 11.7 0.8 0.34 11.0 0.8 1.3 1 0 0 1 1 1 0 Zinc-finger Peptidase_M24 PF00557.24 ETS77024.1 - 1e-40 139.7 0.1 1.6e-40 139.1 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 ETS77024.1 - 7e-11 42.9 0.1 1.1e-10 42.2 0.1 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain PIN_10 PF18478.1 ETS77024.1 - 0.08 13.2 0.0 5.5 7.3 0.0 2.8 3 0 0 3 3 3 0 PIN like domain Peptidase_M28 PF04389.17 ETS77025.1 - 2.1e-29 102.7 0.0 3.1e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 DbpA PF03880.15 ETS77025.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 DbpA RNA binding domain Gsf2 PF11055.8 ETS77025.1 - 0.22 10.2 0.1 0.31 9.8 0.1 1.1 1 0 0 1 1 1 0 Glucose signalling factor 2 SF1-HH PF16275.5 ETS77027.1 - 7.2e-44 148.7 1.2 7.2e-44 148.7 1.2 2.5 1 1 1 2 2 2 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 ETS77027.1 - 1.2e-11 44.1 10.9 1.3e-05 25.0 0.8 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 ETS77027.1 - 6.8e-08 32.2 0.1 1.3e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 ETS77027.1 - 7.7e-07 29.0 4.8 0.0014 18.6 1.9 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 ETS77027.1 - 0.001 18.8 8.3 0.16 11.8 1.0 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 ETS77027.1 - 0.0015 18.2 5.0 0.47 10.2 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 ETS77027.1 - 0.014 15.2 0.5 0.014 15.2 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle ELO PF01151.18 ETS77028.1 - 5.1e-62 209.6 19.1 6.1e-62 209.4 19.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family COX5A PF02284.16 ETS77029.1 - 4e-41 139.2 0.2 5.2e-41 138.8 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Annexin PF00191.20 ETS77029.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Annexin SGL PF08450.12 ETS77030.1 - 4.9e-58 196.6 0.0 7.7e-58 196.0 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region DUF5074 PF16819.5 ETS77030.1 - 0.03 14.4 0.0 0.071 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5074) DUF839 PF05787.13 ETS77030.1 - 0.044 12.9 0.0 8.5 5.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF839) Reg_prop PF07494.11 ETS77030.1 - 0.45 10.9 3.2 20 5.9 0.0 3.7 5 0 0 5 5 5 0 Two component regulator propeller AAA_5 PF07728.14 ETS77033.1 - 2.8e-09 37.1 0.0 5.7e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ETS77033.1 - 8.1e-09 35.8 0.3 3.1e-08 33.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 ETS77033.1 - 2.8e-07 31.0 0.1 2.5e-06 27.9 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ETS77033.1 - 0.00059 19.8 0.0 0.0038 17.2 0.0 2.2 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.26 ETS77033.1 - 0.0017 18.1 0.0 0.0047 16.7 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Torsin PF06309.11 ETS77033.1 - 0.0019 18.3 0.1 0.0058 16.7 0.0 1.8 2 0 0 2 2 2 1 Torsin RuvB_N PF05496.12 ETS77033.1 - 0.0028 17.4 0.0 0.039 13.7 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 ETS77033.1 - 0.0059 16.0 0.2 1.3 8.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 ETS77033.1 - 0.0092 16.4 0.1 0.22 11.9 0.0 2.8 3 1 1 4 4 3 1 AAA ATPase domain AAA_6 PF12774.7 ETS77033.1 - 0.01 14.9 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Ank_4 PF13637.6 ETS77033.1 - 0.032 14.8 0.0 0.069 13.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) RNA_helicase PF00910.22 ETS77033.1 - 0.038 14.4 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 ETS77033.1 - 0.045 13.6 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS77033.1 - 0.071 13.4 0.1 0.27 11.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain UBA_4 PF14555.6 ETS77033.1 - 0.081 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain TsaE PF02367.17 ETS77033.1 - 0.089 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE VWA_2 PF13519.6 ETS77034.1 - 0.00014 22.5 2.0 0.0011 19.6 0.0 3.0 2 1 1 3 3 3 1 von Willebrand factor type A domain TPP_enzyme_C PF02775.21 ETS77034.1 - 0.023 14.5 0.0 0.071 12.9 0.0 1.8 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ribonuc_L-PSP PF01042.21 ETS77035.1 - 2.2e-19 69.6 0.0 2.7e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP WWE PF02825.20 ETS77035.1 - 0.068 13.8 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 WWE domain Fungal_trans_2 PF11951.8 ETS77038.1 - 5.2e-41 140.7 0.6 1.2e-26 93.4 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain NAD_binding_10 PF13460.6 ETS77038.1 - 1e-16 61.4 0.0 2.4e-16 60.2 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS77038.1 - 4.8e-08 32.9 0.0 7.1e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 ETS77038.1 - 0.00014 22.1 0.0 0.00028 21.1 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 ETS77038.1 - 0.011 15.8 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.21 ETS77038.1 - 0.015 14.8 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 ETS77038.1 - 0.02 15.4 0.0 0.037 14.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 ETS77038.1 - 0.021 13.9 0.0 0.038 13.0 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3627 PF12299.8 ETS77038.1 - 0.17 12.0 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) MFS_1 PF07690.16 ETS77039.1 - 1.7e-24 86.4 30.0 1.7e-24 86.4 30.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS77039.1 - 0.0014 18.0 15.8 0.0033 16.8 1.0 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Hydantoinase_B PF02538.14 ETS77040.1 - 5e-201 668.6 0.0 7e-201 668.1 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 ETS77040.1 - 4.6e-101 337.9 0.0 8e-101 337.1 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ETS77040.1 - 1.9e-59 200.4 0.2 6.6e-58 195.3 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.9 ETS77040.1 - 0.071 12.8 0.3 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Utp13 PF08625.11 ETS77041.1 - 2.4e-52 176.6 0.9 4.2e-52 175.8 0.9 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 ETS77041.1 - 8.9e-51 168.8 18.5 5e-06 27.2 0.0 11.6 11 1 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS77041.1 - 4.9e-12 46.0 8.1 0.7 10.2 0.2 8.5 6 4 3 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ETS77041.1 - 0.19 11.0 0.0 53 3.0 0.0 3.6 4 1 0 4 4 4 0 WD40-like domain Lipase_GDSL_2 PF13472.6 ETS77042.1 - 5.5e-11 43.2 1.6 7.8e-11 42.7 1.6 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ALGX PF16822.5 ETS77042.1 - 0.0036 17.0 0.1 0.0062 16.2 0.1 1.4 1 0 0 1 1 1 1 SGNH hydrolase-like domain, acetyltransferase AlgX Lipase_GDSL PF00657.22 ETS77042.1 - 0.0036 17.3 1.2 0.0077 16.2 1.2 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Helo_like_N PF17111.5 ETS77044.1 - 1.2e-84 282.8 2.1 6.4e-80 267.4 0.1 2.2 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins SesA PF17107.5 ETS77044.1 - 0.0012 19.1 1.4 0.45 10.7 0.0 2.9 2 1 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases COG7 PF10191.9 ETS77044.1 - 0.0038 15.5 0.6 0.6 8.3 0.2 2.2 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) Baculo_PEP_C PF04513.12 ETS77044.1 - 0.023 14.7 3.7 7.7 6.6 0.3 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 ETS77044.1 - 0.048 13.9 3.4 5 7.4 0.0 3.6 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Mvb12 PF09452.10 ETS77044.1 - 0.049 14.1 0.2 0.66 10.4 0.0 2.8 3 0 0 3 3 3 0 ESCRT-I subunit Mvb12 RNAse_A_bac PF18431.1 ETS77044.1 - 0.091 13.7 0.2 1.3 10.0 0.2 2.3 2 0 0 2 2 2 0 Bacterial CdiA-CT RNAse A domain DUF1730 PF08331.10 ETS77044.1 - 0.14 12.1 0.1 0.47 10.4 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) DASH_Dad2 PF08654.10 ETS77044.1 - 0.16 12.4 3.5 0.64 10.5 0.1 3.2 3 1 0 3 3 3 0 DASH complex subunit Dad2 Dioxygenase_N PF04444.14 ETS77044.1 - 0.18 11.7 1.0 6.6 6.7 0.1 3.1 3 0 0 3 3 3 0 Catechol dioxygenase N terminus Med10 PF09748.9 ETS77044.1 - 0.23 11.4 1.3 5.1 7.1 0.0 2.9 2 1 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex CdvA PF18822.1 ETS77044.1 - 0.3 10.9 7.5 0.82 9.5 0.1 4.0 5 0 0 5 5 4 0 CdvA-like coiled-coil domain FlaC_arch PF05377.11 ETS77044.1 - 0.84 10.1 5.3 29 5.1 0.0 4.2 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 ETS77044.1 - 1.1 9.8 5.4 5.2 7.6 0.1 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Prefoldin_2 PF01920.20 ETS77044.1 - 1.9 8.5 5.7 10 6.2 0.1 3.8 4 1 0 4 4 3 0 Prefoldin subunit COG2 PF06148.11 ETS77044.1 - 1.9 8.6 5.2 17 5.5 0.5 3.5 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Apolipoprotein PF01442.18 ETS77044.1 - 2.4 8.0 8.0 4.1 7.2 4.0 2.7 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain Helo_like_N PF17111.5 ETS77045.1 - 2.7e-64 216.4 1.8 1.5e-60 204.2 0.1 2.2 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins CorA PF01544.18 ETS77045.1 - 0.0034 16.7 1.5 0.01 15.2 0.1 2.2 1 1 0 2 2 2 1 CorA-like Mg2+ transporter protein SesA PF17107.5 ETS77045.1 - 0.013 15.7 2.8 0.33 11.2 0.0 3.1 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases LMBR1 PF04791.16 ETS77045.1 - 0.17 10.7 1.5 0.27 10.1 1.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein BST2 PF16716.5 ETS77045.1 - 0.35 11.5 4.3 5 7.8 0.6 3.0 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 HAUS6_N PF14661.6 ETS77045.1 - 0.63 9.6 5.7 0.69 9.4 0.7 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus HTH_22 PF13309.6 ETS77046.1 - 0.16 12.1 0.4 0.37 10.9 0.4 1.7 1 1 0 1 1 1 0 HTH domain YjbH PF06082.11 ETS77047.1 - 0.65 8.7 14.3 1.2 7.8 14.3 1.4 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH ADH_zinc_N PF00107.26 ETS77048.1 - 2.1e-07 30.9 0.1 4e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS77049.1 - 1e-05 25.3 0.0 2e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Baculo_PEP_C PF04513.12 ETS77050.1 - 0.36 10.9 2.7 14 5.7 0.5 2.3 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EBP50_C PF09007.11 ETS77051.1 - 0.68 10.9 7.4 1 10.4 7.4 1.4 1 0 0 1 1 1 0 EBP50, C-terminal WD40 PF00400.32 ETS77053.1 - 4.6e-111 359.6 57.7 1.5e-09 38.3 0.1 13.1 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS77053.1 - 6.8e-33 112.8 17.5 0.0017 18.6 0.0 12.2 1 1 11 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 ETS77053.1 - 3.5e-18 66.1 0.0 7.3e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 ETS77053.1 - 4.4e-16 58.7 22.5 0.027 13.4 0.2 10.4 1 1 5 7 7 7 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PNP_UDP_1 PF01048.20 ETS77053.1 - 9.4e-09 34.9 0.0 1.9e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily WD40_like PF17005.5 ETS77053.1 - 2.3e-08 33.8 0.2 0.053 12.8 0.0 5.9 3 3 2 6 6 6 2 WD40-like domain Frtz PF11768.8 ETS77053.1 - 4.3e-07 28.6 0.2 0.19 10.0 0.0 5.6 2 1 3 6 6 6 2 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 ETS77053.1 - 2.3e-06 26.5 36.0 0.76 8.4 3.5 9.4 1 1 8 9 9 9 5 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 ETS77053.1 - 0.025 13.1 4.3 0.08 11.5 0.2 3.1 2 1 0 3 3 3 0 Cytochrome D1 heme domain PQQ_2 PF13360.6 ETS77053.1 - 0.056 13.0 16.4 0.58 9.7 9.6 3.7 1 1 1 2 2 2 0 PQQ-like domain AAA_19 PF13245.6 ETS77053.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sirohm_synth_M PF14824.6 ETS77053.1 - 1 8.9 3.2 11 5.5 0.1 3.4 3 0 0 3 3 3 0 Sirohaem biosynthesis protein central ABC1 PF03109.16 ETS77054.1 - 3.5e-34 117.5 0.0 6.5e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Filo_VP35 PF02097.15 ETS77054.1 - 0.035 13.2 0.4 0.059 12.4 0.4 1.4 1 0 0 1 1 1 0 Filoviridae VP35 CENP-U PF13097.6 ETS77054.1 - 6.5 6.7 6.7 13 5.7 6.7 1.4 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit RRP36 PF06102.12 ETS77055.1 - 5e-47 159.9 24.9 9.5e-47 159.0 24.9 1.5 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 Ank_2 PF12796.7 ETS77057.1 - 1.3e-21 76.9 1.8 1.7e-11 44.5 0.4 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS77057.1 - 4.4e-12 46.0 0.0 1.9e-06 28.0 0.0 5.1 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS77057.1 - 1.4e-11 43.6 0.1 0.079 13.6 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 ETS77057.1 - 5.2e-11 42.5 0.0 0.085 13.3 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 ETS77057.1 - 7.6e-10 39.1 0.1 0.00089 19.8 0.0 4.6 3 1 3 6 6 6 4 Ankyrin repeats (many copies) WcbI PF18588.1 ETS77057.1 - 0.079 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI TPR_7 PF13176.6 ETS77057.1 - 0.081 13.0 0.1 0.3 11.2 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Sugar_tr PF00083.24 ETS77058.1 - 9.3e-63 212.6 14.2 2.1e-62 211.5 14.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS77058.1 - 5.7e-11 41.9 37.6 2.9e-06 26.5 13.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NIF PF03031.18 ETS77059.1 - 2.1e-20 73.0 0.0 3.6e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase C9orf72-like PF15019.6 ETS77059.1 - 0.026 14.1 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 C9orf72-like protein family eIF3_subunit PF08597.10 ETS77059.1 - 0.031 14.2 4.6 0.058 13.3 4.6 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit NARP1 PF12569.8 ETS77059.1 - 0.34 9.7 2.8 0.47 9.3 2.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GREB1 PF15782.5 ETS77059.1 - 0.38 7.8 7.5 0.5 7.4 7.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 ETS77059.1 - 0.58 10.1 19.1 0.83 9.6 19.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TAF4 PF05236.14 ETS77059.1 - 1.1 8.9 8.8 18 4.9 10.3 1.9 1 1 1 2 2 2 0 Transcription initiation factor TFIID component TAF4 family IHABP4_N PF16174.5 ETS77059.1 - 2.3 8.8 12.2 4.1 8.0 12.2 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Ndc1_Nup PF09531.10 ETS77059.1 - 2.8 6.5 5.8 3.7 6.1 5.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.14 ETS77059.1 - 3.4 7.6 8.6 5.6 6.9 8.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.12 ETS77059.1 - 3.5 6.5 7.2 4.9 6.0 7.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ribosomal_S9 PF00380.19 ETS77061.1 - 2.6e-40 137.7 0.3 5.2e-40 136.7 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.19 ETS77062.1 - 1.7e-41 140.6 0.1 3.3e-41 139.7 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 ETS77062.1 - 8.1e-14 51.6 0.1 1.8e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ETS77062.1 - 8.2e-14 51.7 0.1 2.8e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS77062.1 - 5.5e-11 42.3 0.3 2.8e-10 40.1 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ETS77062.1 - 5e-09 36.4 0.0 1.1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ETS77062.1 - 2e-06 28.0 0.0 4.4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ETS77062.1 - 4.3e-06 26.8 0.1 1.5e-05 25.1 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain EF-hand_1 PF00036.32 ETS77063.1 - 4.5e-23 79.0 12.2 2e-07 30.1 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ETS77063.1 - 1.5e-18 67.0 6.6 2.3e-14 53.6 1.4 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 ETS77063.1 - 2.5e-16 58.1 5.9 3.8e-05 23.3 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 ETS77063.1 - 1.1e-14 53.2 9.2 1.4e-06 27.5 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 ETS77063.1 - 4.9e-12 45.5 9.0 0.00013 21.8 0.7 4.1 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 ETS77063.1 - 1.2e-06 28.5 4.7 0.0018 18.2 0.5 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ETS77063.1 - 0.0003 21.1 0.1 0.00093 19.5 0.1 1.8 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 ETS77063.1 - 0.023 14.9 0.8 0.089 13.0 0.7 2.1 1 1 0 1 1 1 0 Dockerin type I domain EPL1 PF10513.9 ETS77064.1 - 4.7e-18 66.1 2.7 4.7e-18 66.1 2.7 2.9 3 1 0 3 3 3 1 Enhancer of polycomb-like FAM167 PF11652.8 ETS77064.1 - 0.029 14.8 2.3 0.083 13.4 2.0 2.0 2 0 0 2 2 2 0 FAM167 Peptidase_M22 PF00814.25 ETS77065.1 - 9.2e-79 264.9 0.0 1.1e-78 264.6 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family AMPK1_CBM PF16561.5 ETS77066.1 - 1.1e-21 76.8 0.0 2e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 ETS77066.1 - 1e-18 67.4 1.1 1e-18 67.4 1.1 2.4 3 0 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interaction domain Pkinase PF00069.25 ETS77068.1 - 9.2e-63 212.1 0.0 1.1e-62 211.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS77068.1 - 3.2e-30 105.3 0.0 4.3e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ETS77068.1 - 0.00042 19.4 0.1 0.00059 18.9 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ETS77068.1 - 0.0041 16.5 0.0 0.0075 15.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 ETS77068.1 - 0.015 15.0 0.1 0.15 11.7 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 ETS77068.1 - 0.074 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase CMAS PF02353.20 ETS77069.1 - 3.9e-36 124.8 0.7 5.8e-36 124.2 0.7 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ETS77069.1 - 5.5e-16 59.0 0.0 1e-15 58.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS77069.1 - 2.4e-15 57.0 0.0 4.2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS77069.1 - 5.7e-15 55.4 0.0 9.2e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS77069.1 - 6.7e-11 42.8 0.0 1.3e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS77069.1 - 1.5e-10 41.2 0.0 2.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS77069.1 - 3e-08 33.4 0.0 5.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 ETS77069.1 - 1.2e-06 28.0 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 ETS77069.1 - 5.6e-06 26.3 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltr_RsmB-F PF01189.17 ETS77069.1 - 3.6e-05 23.5 0.0 0.00011 21.9 0.0 1.7 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_4 PF02390.17 ETS77069.1 - 0.00015 21.3 0.0 0.0016 17.9 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase TehB PF03848.14 ETS77069.1 - 0.00034 20.1 0.0 0.00055 19.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB GidB PF02527.15 ETS77069.1 - 0.00036 19.9 0.0 0.00059 19.2 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PCMT PF01135.19 ETS77069.1 - 0.0013 18.5 0.0 0.003 17.3 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 ETS77069.1 - 0.025 13.5 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 ETS77069.1 - 0.051 13.3 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Recep_L_domain PF01030.24 ETS77069.1 - 0.16 12.1 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 Receptor L domain UCH PF00443.29 ETS77070.1 - 1e-27 97.3 0.0 1.5e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 ETS77070.1 - 2.2e-12 47.1 0.2 4.2e-12 46.2 0.2 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 ETS77070.1 - 0.0071 16.0 0.1 0.034 13.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1064 PF06356.11 ETS77070.1 - 0.084 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1064) Es2 PF09751.9 ETS77071.1 - 9.6e-128 427.6 7.9 1.2e-127 427.2 7.9 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 DUF3433 PF11915.8 ETS77072.1 - 1.8e-41 140.5 8.7 1.6e-23 83.0 0.5 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Glyco_hydro_61 PF03443.14 ETS77073.1 - 0.048 13.6 2.5 0.067 13.1 0.0 2.2 2 1 0 2 2 2 0 Glycosyl hydrolase family 61 Cu-oxidase PF00394.22 ETS77074.1 - 1.3e-41 142.4 0.3 2.6e-41 141.4 0.3 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 ETS77074.1 - 2.2e-40 137.4 1.7 2.2e-40 137.4 1.7 3.6 5 0 0 5 5 5 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ETS77074.1 - 2.9e-38 130.7 15.1 2.8e-37 127.5 1.2 4.1 3 1 0 3 3 3 2 Multicopper oxidase GGACT PF06094.12 ETS77075.1 - 1.2e-15 58.1 0.1 1.7e-15 57.7 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like FAT PF02259.23 ETS77076.1 - 1.2e-71 241.7 5.2 3.4e-71 240.3 5.2 1.9 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 ETS77076.1 - 2.3e-31 109.5 0.2 9.6e-31 107.5 0.2 2.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 ETS77076.1 - 2.3e-08 33.7 0.2 7.1e-08 32.1 0.2 1.9 1 0 0 1 1 1 1 FATC domain TPR_1 PF00515.28 ETS77076.1 - 0.14 12.1 11.3 21 5.2 0.2 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 ETS77076.1 - 0.34 11.1 12.9 5.4 7.4 0.2 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat SOG2 PF10428.9 ETS77076.1 - 0.41 9.8 7.2 1.4 8.1 7.2 1.8 1 0 0 1 1 1 0 RAM signalling pathway protein TPR_17 PF13431.6 ETS77076.1 - 0.91 10.0 6.9 13 6.5 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 ETS77076.1 - 7 7.1 12.9 0.21 11.9 1.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat PhoLip_ATPase_C PF16212.5 ETS77077.1 - 1.5e-49 169.1 3.6 1.5e-49 169.1 3.6 1.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ETS77077.1 - 6.3e-16 57.8 0.8 1.3e-15 56.8 0.8 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 ETS77077.1 - 9e-14 52.3 0.1 9.6e-08 32.6 0.2 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ETS77077.1 - 7.4e-08 32.1 0.3 0.00072 19.1 0.0 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 ETS77077.1 - 3.8e-06 26.9 0.0 0.00015 21.8 0.0 2.9 3 1 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ETS77077.1 - 0.0026 17.5 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glycogen_syn PF05693.13 ETS77078.1 - 0 1173.0 0.0 0 1172.8 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 ETS77078.1 - 3.4e-05 23.7 0.1 6.7e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 ETS77078.1 - 6.3e-05 23.0 0.2 0.00014 21.9 0.2 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 ETS77078.1 - 7.4e-05 22.3 0.0 0.024 14.2 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ETS77078.1 - 0.00029 21.3 0.0 0.22 12.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ETS77078.1 - 0.00047 20.6 0.0 0.0012 19.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Fungal_lectin_2 PF18647.1 ETS77079.1 - 5.5e-25 87.8 0.6 8.4e-25 87.2 0.6 1.3 1 0 0 1 1 1 1 Alpha-galactosyl-binding fungal lectin F-box-like PF12937.7 ETS77080.1 - 7.2e-08 32.2 0.1 1.9e-07 30.8 0.1 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 ETS77080.1 - 0.041 13.8 1.3 8.2 6.4 0.1 2.5 2 0 0 2 2 2 0 F-box domain ABC_tran PF00005.27 ETS77081.1 - 7.6e-39 133.4 0.0 1.8e-18 67.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS77081.1 - 2.1e-36 126.0 15.4 5.3e-31 108.3 8.8 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 ETS77081.1 - 6e-07 29.6 6.5 0.2 11.4 0.3 4.3 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ETS77081.1 - 1e-06 29.1 0.0 0.044 14.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ETS77081.1 - 3.1e-06 26.8 0.4 0.081 12.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ETS77081.1 - 3.4e-06 27.5 0.1 0.025 15.0 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 ETS77081.1 - 5.9e-06 25.9 6.3 1.1 8.6 0.9 4.4 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 ETS77081.1 - 5.7e-05 23.3 0.5 0.0012 18.9 0.0 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 ETS77081.1 - 0.00012 22.0 0.1 0.7 9.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 ETS77081.1 - 0.0003 20.3 0.0 0.38 10.2 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 ETS77081.1 - 0.00031 20.8 0.0 0.41 10.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SSE PF00437.20 ETS77081.1 - 0.00054 19.1 0.0 0.86 8.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 ETS77081.1 - 0.00061 18.8 0.0 0.059 12.3 0.0 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.6 ETS77081.1 - 0.0014 18.8 1.1 0.49 10.6 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 ETS77081.1 - 0.002 18.7 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 ETS77081.1 - 0.0094 15.7 0.0 0.52 10.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 ETS77081.1 - 0.013 15.1 0.0 3 7.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 ETS77081.1 - 0.013 15.3 0.2 0.58 9.9 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SbcCD_C PF13558.6 ETS77081.1 - 0.017 15.3 2.6 23 5.3 0.6 4.4 4 1 0 4 4 3 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 ETS77081.1 - 0.02 15.4 0.1 2.7 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ETS77081.1 - 0.025 13.9 0.1 2.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 ETS77081.1 - 0.026 14.6 0.4 5.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Dynamin family cobW PF02492.19 ETS77081.1 - 0.026 14.1 0.0 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 ETS77081.1 - 0.028 14.8 0.0 14 6.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 ETS77081.1 - 0.03 14.8 0.0 2.7 8.4 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 ETS77081.1 - 0.031 14.0 1.3 0.53 10.0 0.0 3.1 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 ETS77081.1 - 0.044 13.8 0.3 12 5.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.7 ETS77081.1 - 0.05 12.5 0.0 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.18 ETS77081.1 - 0.092 12.1 0.2 0.88 8.9 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.13 ETS77081.1 - 0.096 11.8 0.0 8.4 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) CLP1_P PF16575.5 ETS77081.1 - 0.1 12.4 0.3 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop IstB_IS21 PF01695.17 ETS77081.1 - 0.15 11.8 0.2 12 5.5 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 ETS77081.1 - 0.2 11.0 0.2 29 4.0 0.0 2.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI dNK PF01712.19 ETS77081.1 - 0.26 11.1 0.1 26 4.6 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase DHHA2 PF02833.14 ETS77083.1 - 8.1e-15 55.3 0.0 1.2e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 ETS77083.1 - 1e-08 35.3 0.1 2.2e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 DHH family SPECT1 PF18680.1 ETS77083.1 - 0.53 9.9 3.6 0.31 10.7 1.0 1.7 2 0 0 2 2 2 0 Plasmodium host cell traversal SPECT1 Abhydrolase_1 PF00561.20 ETS77084.1 - 1.9e-12 47.4 0.1 7.9e-12 45.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS77084.1 - 6.5e-06 26.9 0.1 1.4e-05 25.8 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family UPF0227 PF05728.12 ETS77084.1 - 0.037 14.0 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) GMC_oxred_N PF00732.19 ETS77085.1 - 4.6e-65 219.9 0.0 5.8e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS77085.1 - 1.2e-34 119.9 0.0 2e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS77085.1 - 1.3e-06 27.8 0.4 0.012 14.8 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS77085.1 - 2.3e-06 27.7 0.0 1e-05 25.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS77085.1 - 7.1e-06 25.5 0.0 0.017 14.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS77085.1 - 7.2e-05 22.2 0.2 0.31 10.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS77085.1 - 0.00034 19.8 0.1 0.0011 18.1 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 ETS77085.1 - 0.00038 20.2 4.7 0.0053 16.4 3.9 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS77085.1 - 0.00073 18.4 0.1 0.0058 15.4 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 ETS77085.1 - 0.0016 17.7 0.0 0.0056 16.0 0.0 1.8 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.27 ETS77085.1 - 0.016 15.7 0.1 0.92 10.1 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 ETS77086.1 - 8.8e-58 196.2 0.0 1.2e-57 195.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 ETS77086.1 - 5.5e-24 85.2 0.0 1.9e-23 83.5 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RTA1 PF04479.13 ETS77087.1 - 0.0067 16.0 6.2 0.0097 15.5 6.2 1.3 1 0 0 1 1 1 1 RTA1 like protein Frizzled PF01534.17 ETS77087.1 - 0.017 14.2 0.2 0.022 13.8 0.2 1.3 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region FA_desaturase PF00487.24 ETS77087.1 - 0.16 11.8 2.6 0.24 11.2 2.6 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Sulfotransfer_4 PF17784.1 ETS77088.1 - 2e-53 181.4 0.0 2.7e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ETS77088.1 - 0.0018 18.7 0.1 0.34 11.2 0.0 2.4 1 1 0 2 2 2 2 Sulfotransferase family DUF3632 PF12311.8 ETS77090.1 - 2.1e-31 109.7 1.0 3.3e-31 109.1 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) Apo-CIII PF05778.12 ETS77090.1 - 0.077 12.6 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) HET PF06985.11 ETS77091.1 - 8.9e-29 100.7 0.9 1.6e-28 99.9 0.9 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mit_ribos_Mrp51 PF11709.8 ETS77091.1 - 0.09 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit DUF3433 PF11915.8 ETS77091.1 - 0.11 12.9 0.4 0.72 10.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3433) Sterol_MT_C PF08498.10 ETS77092.1 - 7.7e-29 99.8 0.2 1.4e-28 99.0 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 ETS77092.1 - 3.8e-21 75.6 0.0 6.9e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS77092.1 - 3.6e-19 69.3 0.0 6.7e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS77092.1 - 1.2e-17 64.1 0.0 1.8e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS77092.1 - 3.2e-11 43.3 0.1 6.8e-11 42.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS77092.1 - 2.8e-10 40.8 0.1 1e-09 39.0 0.0 2.0 3 0 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS77092.1 - 2.2e-09 37.0 0.0 3.5e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 ETS77092.1 - 1.6e-08 34.2 0.1 2.4e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 ETS77092.1 - 0.00031 19.4 0.0 0.00044 18.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_15 PF09445.10 ETS77092.1 - 0.0033 17.0 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.20 ETS77092.1 - 0.0035 16.5 0.0 0.0052 15.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 ETS77092.1 - 0.0075 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 ETS77092.1 - 0.0089 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 ETS77092.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain SPT2 PF08243.11 ETS77092.1 - 0.019 15.5 1.8 0.039 14.5 1.8 1.4 1 0 0 1 1 1 0 SPT2 chromatin protein PrmA PF06325.13 ETS77092.1 - 0.078 12.4 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 ETS77092.1 - 0.095 12.7 0.2 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain F-box-like PF12937.7 ETS77094.1 - 0.058 13.3 0.4 0.058 13.3 0.4 1.8 2 0 0 2 2 2 0 F-box-like MFS_1 PF07690.16 ETS77095.1 - 2.1e-38 132.1 39.3 2.1e-38 132.1 39.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS77095.1 - 3.5e-12 45.9 5.7 3.5e-12 45.9 5.7 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 ETS77095.1 - 0.00099 17.5 4.0 0.00099 17.5 4.0 3.2 2 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family LNP1 PF15419.6 ETS77096.1 - 0.046 13.9 0.3 0.085 13.1 0.3 1.5 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 FTA2 PF13095.6 ETS77097.1 - 8.7e-53 179.1 0.1 1.2e-52 178.6 0.1 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 ETS77097.1 - 0.013 14.8 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DUF3322 PF11795.8 ETS77097.1 - 0.028 14.4 0.3 0.062 13.3 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) COesterase PF00135.28 ETS77098.1 - 5.1e-74 250.0 0.8 3e-73 247.4 0.8 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS77098.1 - 2.5e-05 24.3 0.3 5.5e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS77098.1 - 0.011 15.3 0.2 0.024 14.1 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Herpes_capsid PF06112.11 ETS77098.1 - 5.2 7.1 8.9 10 6.1 8.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein NOA36 PF06524.12 ETS77099.1 - 0.064 12.6 13.6 0.095 12.0 13.6 1.2 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 ETS77099.1 - 0.073 12.9 8.1 0.077 12.9 7.0 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region SDA1 PF05285.12 ETS77099.1 - 0.84 9.0 13.3 1.2 8.5 13.3 1.2 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 ETS77099.1 - 1.7 8.3 14.6 2.8 7.6 14.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2722 PF10846.8 ETS77099.1 - 2.6 6.9 8.7 3.3 6.5 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Nop14 PF04147.12 ETS77099.1 - 7.9 4.6 15.7 9.6 4.3 15.7 1.1 1 0 0 1 1 1 0 Nop14-like family HET PF06985.11 ETS77100.1 - 1.8e-31 109.4 0.1 3.4e-31 108.5 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cytadhesin_P30 PF07271.11 ETS77100.1 - 0.088 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 FxsA PF04186.13 ETS77100.1 - 0.11 12.7 1.5 0.24 11.5 1.5 1.6 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein LolA PF03548.15 ETS77103.1 - 0.075 12.7 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA Mid2 PF04478.12 ETS77103.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Cellulase PF00150.18 ETS77105.1 - 4.4e-35 121.5 2.4 6.1e-35 121.0 2.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 ETS77105.1 - 1.8e-18 66.4 1.7 4.9e-18 65.0 1.4 2.0 2 0 0 2 2 2 1 Carbohydrate binding domain X2 Glyco_hydro_3 PF00933.21 ETS77106.1 - 3.3e-44 151.5 0.0 5.2e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 ETS77106.1 - 2.3e-38 132.2 0.0 3.6e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ETS77106.1 - 2.5e-14 53.1 0.1 4.7e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Peptidase_S15 PF02129.18 ETS77107.1 - 1.2e-60 205.4 0.1 1.7e-60 204.9 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ETS77107.1 - 7.7e-46 156.8 0.0 1.1e-45 156.4 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_1 PF00561.20 ETS77107.1 - 9.3e-09 35.3 0.1 8.7e-08 32.1 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS77107.1 - 1.3e-07 31.1 0.1 2.5e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ETS77107.1 - 1.3e-05 24.8 0.1 3.2e-05 23.5 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 ETS77107.1 - 4.7e-05 24.1 0.7 4.7e-05 24.1 0.7 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 ETS77107.1 - 0.0005 18.8 0.1 0.0049 15.6 0.0 2.0 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 ETS77107.1 - 0.04 13.8 0.1 0.28 11.0 0.1 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_129 PF11308.8 ETS77107.1 - 0.051 12.7 0.1 0.084 12.0 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases related to GH101 family, GH129 DLH PF01738.18 ETS77107.1 - 0.066 12.8 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF2048 PF09752.9 ETS77107.1 - 0.17 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 CDC45 PF02724.14 ETS77108.1 - 8.3 4.6 9.0 9.9 4.3 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Aa_trans PF01490.18 ETS77109.1 - 1.2e-36 126.3 37.3 1.5e-36 126.0 37.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SLATT_fungal PF18142.1 ETS77109.1 - 0.79 9.7 0.0 0.79 9.7 0.0 3.7 4 1 0 4 4 4 0 SMODS and SLOG-associating 2TM effector domain Tetraspanin PF00335.20 ETS77109.1 - 1.1 8.9 0.0 1.1 8.9 0.0 4.2 5 1 0 5 5 5 0 Tetraspanin family Hydin_ADK PF17213.3 ETS77110.1 - 0.89 9.8 8.0 1.3 9.3 8.0 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain ABC_membrane PF00664.23 ETS77111.1 - 5.2e-85 285.4 46.0 1.6e-42 146.0 21.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ETS77111.1 - 6.3e-63 211.4 0.0 2.9e-30 105.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ETS77111.1 - 2.6e-15 56.5 6.5 2.4e-05 23.9 1.5 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 ETS77111.1 - 7.6e-10 38.2 0.0 0.0005 19.0 0.0 3.4 3 0 0 3 3 3 3 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 ETS77111.1 - 1.3e-08 34.9 0.0 5.7e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ETS77111.1 - 1.7e-08 34.8 0.3 0.012 15.9 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ETS77111.1 - 1.4e-07 32.1 0.1 0.0058 17.0 0.0 3.7 3 1 0 3 3 3 2 AAA ATPase domain AAA_15 PF13175.6 ETS77111.1 - 1.2e-06 28.5 0.0 0.013 15.2 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ETS77111.1 - 2.6e-06 27.1 0.9 0.0024 17.6 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 ETS77111.1 - 4.2e-06 26.6 0.1 0.079 12.7 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_21 PF13304.6 ETS77111.1 - 5.6e-06 26.4 0.1 0.037 13.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ETS77111.1 - 1.7e-05 25.4 0.7 0.0096 16.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ETS77111.1 - 0.00011 22.7 0.0 0.57 10.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 ETS77111.1 - 0.00026 20.9 0.1 0.13 12.2 0.0 2.9 3 0 0 3 3 3 1 Rad17 P-loop domain AAA PF00004.29 ETS77111.1 - 0.00027 21.4 2.7 1.4 9.4 0.1 4.5 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ETS77111.1 - 0.00033 20.3 0.0 0.09 12.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 ETS77111.1 - 0.0014 18.8 0.1 1.7 8.9 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 ETS77111.1 - 0.002 17.9 0.0 2.7 7.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 ETS77111.1 - 0.004 16.7 0.0 2 7.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region PRK PF00485.18 ETS77111.1 - 0.0084 15.9 0.1 3.5 7.3 0.0 2.7 3 0 0 3 3 2 1 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.14 ETS77111.1 - 0.0085 16.1 0.0 11 6.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 ETS77111.1 - 0.013 15.3 1.5 8.7 6.0 0.0 3.4 3 1 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 ETS77111.1 - 0.015 15.0 0.3 2.6 7.7 0.0 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 ETS77111.1 - 0.017 15.4 0.2 4.7 7.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ETS77111.1 - 0.053 13.8 0.5 25 5.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 ETS77111.1 - 0.075 13.4 0.0 16 5.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Cytidylate_kin PF02224.18 ETS77111.1 - 0.083 12.6 0.4 3 7.5 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase AAA_33 PF13671.6 ETS77111.1 - 0.11 12.7 0.1 4.1 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ETS77111.1 - 0.12 12.5 0.2 5 7.2 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 ETS77111.1 - 0.15 12.1 0.1 26 4.8 0.0 3.5 4 0 0 4 4 4 0 AAA domain DUF87 PF01935.17 ETS77111.1 - 0.26 11.4 1.0 3.4 7.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain FoP_duplication PF13865.6 ETS77111.1 - 9.7 6.8 30.5 12 6.5 12.1 2.7 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 FSH1 PF03959.13 ETS77112.1 - 1.6e-29 103.1 0.0 5.2e-29 101.4 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ketoacyl-synt PF00109.26 ETS77113.1 - 2.2e-72 243.7 0.0 1.3e-71 241.2 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ETS77113.1 - 3.6e-61 206.2 0.1 8.4e-61 205.0 0.1 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 ETS77113.1 - 4.4e-51 173.9 0.1 7.1e-51 173.2 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ETS77113.1 - 2e-48 165.6 0.0 3.5e-48 164.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ETS77113.1 - 4.7e-39 133.1 0.0 2.1e-38 131.0 0.0 2.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ETS77113.1 - 1.5e-19 70.5 0.0 5.7e-19 68.6 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 ETS77113.1 - 1.9e-17 63.4 0.7 1e-16 61.0 0.1 2.3 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 ETS77113.1 - 1.4e-16 60.6 0.0 5.2e-16 58.8 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS77113.1 - 1.5e-12 48.7 0.0 7.4e-12 46.5 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 ETS77113.1 - 4.1e-09 36.4 0.2 4.1e-09 36.4 0.2 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 ETS77113.1 - 7.4e-08 32.2 0.1 2.3e-07 30.6 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 ETS77113.1 - 0.00017 21.8 0.2 0.00044 20.5 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 ETS77113.1 - 0.00098 18.5 0.1 0.0023 17.3 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.15 ETS77113.1 - 0.056 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Phytase PF02333.15 ETS77115.1 - 8.3e-61 206.0 4.0 4.1e-60 203.7 1.7 2.1 2 0 0 2 2 2 2 Phytase EGF_2 PF07974.13 ETS77115.1 - 0.00041 20.7 26.8 0.051 13.9 14.4 2.5 2 0 0 2 2 2 2 EGF-like domain Radical_SAM_C PF16199.5 ETS77116.1 - 2.3e-32 110.8 0.0 4.6e-32 109.9 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 ETS77116.1 - 9.9e-16 58.6 0.0 2.9e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 ETS77116.1 - 2e-09 37.7 0.1 4e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS77116.1 - 3.7e-06 26.9 0.0 9.6e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS77116.1 - 0.021 15.2 0.1 0.052 14.0 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UQ_con PF00179.26 ETS77117.1 - 3.6e-44 149.8 0.0 4.8e-44 149.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 ETS77117.1 - 2e-06 27.5 0.0 3.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 ETS77117.1 - 0.00027 20.6 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ETS77117.1 - 0.0069 16.7 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 RWD domain SnAPC_2_like PF11035.8 ETS77117.1 - 0.009 16.2 0.4 0.012 15.8 0.4 1.1 1 0 0 1 1 1 1 Small nuclear RNA activating complex subunit 2, SNAP190 Myb DUF1421 PF07223.11 ETS77117.1 - 0.013 15.3 0.2 0.024 14.4 0.2 1.4 1 0 0 1 1 1 0 UBA-like domain (DUF1421) UEV PF05743.13 ETS77117.1 - 0.081 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF373 PF04123.13 ETS77118.1 - 0.16 11.4 0.5 0.27 10.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Pneumo_att_G PF05539.11 ETS77118.1 - 1.3 8.6 7.0 1.7 8.2 7.0 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Peptidase_U4 PF03419.13 ETS77118.1 - 5.3 6.2 7.2 13 4.9 0.4 2.1 2 0 0 2 2 2 0 Sporulation factor SpoIIGA DOPA_dioxygen PF08883.11 ETS77119.1 - 9.4e-30 103.0 0.0 1.2e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family COesterase PF00135.28 ETS77120.1 - 1e-69 235.8 0.0 3.8e-63 214.1 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS77120.1 - 3.9e-08 33.4 0.1 1.2e-07 31.9 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Collagen PF01391.18 ETS77121.1 - 0.0052 16.5 1.0 0.009 15.7 1.0 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Ribonuclease_T2 PF00445.18 ETS77123.1 - 1.5e-34 119.8 0.0 2e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Zn_clus PF00172.18 ETS77124.1 - 7.3e-09 35.6 13.0 1.4e-08 34.7 13.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS77124.1 - 2.9e-05 23.2 6.1 5.8e-05 22.2 5.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain WSC PF01822.19 ETS77125.1 - 1.7e-35 121.0 22.4 5.5e-18 64.9 9.1 2.2 2 0 0 2 2 2 2 WSC domain NmrA PF05368.13 ETS77126.1 - 1e-22 80.9 0.0 1.8e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS77126.1 - 7.4e-14 52.1 0.0 1.6e-13 51.0 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ETS77126.1 - 1.5e-05 24.2 0.1 2.2e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 ETS77126.1 - 0.00086 19.3 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ETS77126.1 - 0.0015 18.7 0.0 0.0024 18.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ETS77126.1 - 0.014 14.9 0.1 0.026 14.0 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family COX_ARM PF06481.14 ETS77126.1 - 0.096 12.6 0.2 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 COX Aromatic Rich Motif Dioxygenase_C PF00775.21 ETS77127.1 - 1.7e-09 37.3 0.1 2.9e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase Zn_clus PF00172.18 ETS77128.1 - 2e-06 27.8 6.1 4.6e-06 26.6 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 ETS77129.1 - 3.7e-42 141.5 22.5 1.6e-08 35.1 1.6 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 ETS77129.1 - 3.6e-37 127.5 0.8 5.1e-37 127.0 0.8 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 ETS77129.1 - 9e-13 48.3 0.1 0.0018 18.5 0.0 5.5 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 ETS77129.1 - 1.7e-08 34.1 0.0 3.7e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 LisH RAB3GAP2_N PF14655.6 ETS77129.1 - 0.00025 20.4 0.0 0.7 9.1 0.0 2.3 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Nucleoporin_N PF08801.11 ETS77129.1 - 0.0016 17.3 0.2 4.7 5.8 0.0 3.7 2 2 1 4 4 4 2 Nup133 N terminal like Nup160 PF11715.8 ETS77129.1 - 0.02 13.6 0.3 5 5.6 0.0 2.6 3 0 0 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 ETS77129.1 - 0.1 11.9 0.0 62 2.8 0.0 3.9 2 1 2 4 4 4 0 WD40-like domain Ge1_WD40 PF16529.5 ETS77129.1 - 0.11 11.5 0.0 2.1 7.2 0.0 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Med11 PF10280.9 ETS77130.1 - 6.7e-46 156.1 0.1 7.9e-46 155.9 0.1 1.0 1 0 0 1 1 1 1 Mediator complex protein SOG2 PF10428.9 ETS77130.1 - 0.15 11.2 0.3 2.2 7.4 0.0 2.3 3 0 0 3 3 3 0 RAM signalling pathway protein Secretin_N_2 PF07655.13 ETS77130.1 - 0.22 12.1 3.1 0.71 10.5 0.2 2.6 1 1 1 3 3 3 0 Secretin N-terminal domain Vps5 PF09325.10 ETS77131.1 - 5.5e-87 291.2 10.4 5.5e-87 291.2 10.4 1.9 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 ETS77131.1 - 4e-25 88.0 0.1 8.3e-25 87.0 0.1 1.6 1 0 0 1 1 1 1 PX domain BAR_2 PF10455.9 ETS77131.1 - 0.0001 21.5 3.8 0.00042 19.6 3.8 1.9 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 ETS77131.1 - 0.00049 19.9 9.2 0.0085 15.8 4.4 2.6 1 1 1 2 2 2 2 BAR domain of APPL family BAR_3_WASP_bdg PF10456.9 ETS77131.1 - 0.00066 19.2 2.2 0.01 15.3 0.2 2.2 1 1 1 2 2 2 2 WASP-binding domain of Sorting nexin protein Lipase_GDSL PF00657.22 ETS77131.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF3450 PF11932.8 ETS77131.1 - 0.19 11.0 8.6 0.13 11.6 6.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF713 PF05218.14 ETS77131.1 - 3 7.5 7.3 1.8 8.3 2.5 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF713) BAR PF03114.18 ETS77131.1 - 3.2 7.3 14.6 1.3 8.6 10.8 2.2 2 1 0 2 2 2 0 BAR domain Ribosomal_L31 PF01197.18 ETS77132.1 - 0.00083 19.5 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L31 Paramyxo_C PF01692.18 ETS77132.1 - 0.055 12.8 0.6 1.1 8.6 0.2 2.2 1 1 1 2 2 2 0 Paramyxovirus non-structural protein C Flavin_Reduct PF01613.18 ETS77133.1 - 1.8e-20 73.5 0.1 1.8e-19 70.3 0.0 2.4 2 1 0 2 2 2 1 Flavin reductase like domain DUF3665 PF12427.8 ETS77133.1 - 0.2 11.4 0.6 0.83 9.4 0.1 2.3 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase EspF PF04806.12 ETS77134.1 - 0.025 15.0 1.0 0.062 13.7 0.3 1.9 2 0 0 2 2 2 0 EspF protein repeat Uteroglobin PF01099.17 ETS77136.1 - 0.19 12.1 0.2 0.19 12.1 0.2 2.0 2 1 1 3 3 3 0 Uteroglobin family Arg_tRNA_synt_N PF03485.16 ETS77136.1 - 2.5 8.7 7.4 5.9 7.5 1.1 3.2 3 0 0 3 3 3 0 Arginyl tRNA synthetase N terminal domain PRIMA1 PF16101.5 ETS77137.1 - 0.18 11.9 2.4 0.31 11.1 2.4 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Zn_clus PF00172.18 ETS77138.1 - 2.3e-08 34.0 14.4 4.4e-08 33.1 14.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS77139.1 - 2.5e-17 62.8 0.4 3.6e-17 62.3 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS77139.1 - 1.9e-06 27.9 11.3 3.6e-06 27.0 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 ETS77140.1 - 2.9e-79 265.9 0.0 3.6e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS77140.1 - 1.2e-06 28.5 0.0 1.8e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding DUF2498 PF10692.9 ETS77140.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2498) Dynamin_M PF01031.20 ETS77141.1 - 5.6e-102 340.8 1.0 6.7e-102 340.5 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 ETS77141.1 - 5.4e-56 189.3 0.0 1e-55 188.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 ETS77141.1 - 1.2e-29 102.3 7.5 1.2e-29 102.3 7.5 2.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 ETS77141.1 - 1.3e-05 25.2 0.2 0.00015 21.8 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 ETS77141.1 - 0.011 15.5 1.7 2.3 7.8 0.1 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.6 ETS77141.1 - 0.086 13.2 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.32 ETS77142.1 - 2.7e-23 81.8 19.9 0.00023 21.9 0.1 7.4 7 1 1 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS77142.1 - 7.8e-12 45.3 2.6 0.064 13.6 0.1 5.8 2 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 ETS77142.1 - 0.0045 16.1 0.0 2.6 7.0 0.0 2.5 1 1 1 2 2 2 2 Coatomer WD associated region WD40_3 PF15911.5 ETS77142.1 - 0.0093 16.0 0.0 0.72 9.9 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat Nbas_N PF15492.6 ETS77142.1 - 0.044 13.1 0.0 0.2 10.9 0.0 2.1 1 1 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 ETS77142.1 - 0.048 12.6 5.0 0.18 10.8 0.4 3.3 3 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ETS77142.1 - 0.2 10.9 0.0 9.5 5.4 0.0 2.7 2 1 1 3 3 3 0 WD40-like domain AMP-binding PF00501.28 ETS77143.1 - 7.4e-44 150.0 0.0 9.7e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 ETS77143.1 - 1e-05 25.4 0.2 2.4e-05 24.2 0.2 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Acetyltransf_2 PF00797.17 ETS77144.1 - 4.1e-34 118.4 0.2 2.6e-33 115.8 0.2 2.0 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 ETS77144.1 - 0.0063 17.0 0.0 0.016 15.7 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily HupH_C PF04809.13 ETS77144.1 - 0.15 11.8 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region Acetyltransf_3 PF13302.7 ETS77145.1 - 8.7e-14 52.4 0.0 1.5e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS77145.1 - 0.0049 17.1 0.0 0.0077 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 ETS77145.1 - 0.056 13.6 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HEV_ORF1 PF02444.16 ETS77145.1 - 0.072 13.7 0.9 0.15 12.6 0.9 1.5 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) GNAT_acetyltran PF12746.7 ETS77145.1 - 0.095 12.3 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase FAD_binding_3 PF01494.19 ETS77146.1 - 3.4e-10 39.7 0.6 8.8e-06 25.2 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ETS77146.1 - 0.00022 20.6 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS77146.1 - 0.0013 17.5 0.2 0.027 13.2 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 ETS77146.1 - 0.0071 16.0 0.3 3.2 7.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS77146.1 - 0.03 13.4 0.4 0.05 12.7 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 ETS77146.1 - 0.047 13.0 0.1 0.073 12.4 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS77146.1 - 0.052 12.8 0.0 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS77146.1 - 0.12 11.6 0.0 0.69 9.1 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Abhydrolase_1 PF00561.20 ETS77147.1 - 5.8e-19 68.7 0.0 1.4e-17 64.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS77147.1 - 1.2e-13 50.9 0.0 2.1e-12 46.9 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS77147.1 - 4e-11 44.0 0.0 6.9e-11 43.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 ETS77147.1 - 0.049 13.2 0.0 0.13 11.8 0.0 1.6 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 ETS77147.1 - 0.17 11.3 0.0 0.83 9.1 0.0 2.0 2 1 0 2 2 2 0 Prolyl oligopeptidase family HET PF06985.11 ETS77148.1 - 4.5e-20 72.5 0.5 3.8e-19 69.5 0.5 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DNA_pol_phi PF04931.13 ETS77148.1 - 0.074 11.1 7.3 0.11 10.6 7.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pex14_N PF04695.13 ETS77148.1 - 0.31 11.7 4.6 0.91 10.2 0.2 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nop14 PF04147.12 ETS77148.1 - 1.9 6.6 8.7 2.8 6.1 8.7 1.1 1 0 0 1 1 1 0 Nop14-like family PAPA-1 PF04795.12 ETS77148.1 - 7.1 7.5 7.6 0.42 11.4 1.8 1.9 2 0 0 2 2 2 0 PAPA-1-like conserved region Ank_2 PF12796.7 ETS77149.1 - 5.4e-24 84.6 2.7 5.9e-15 55.6 0.0 6.9 6 2 0 6 6 6 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS77149.1 - 5.1e-22 77.9 10.3 8.8e-09 35.7 0.0 8.8 5 3 3 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS77149.1 - 1.9e-18 64.6 7.8 0.0019 18.5 0.0 8.9 9 0 0 9 9 9 3 Ankyrin repeat Clr5 PF14420.6 ETS77149.1 - 1.8e-17 63.3 1.4 5.9e-17 61.6 1.4 2.0 1 0 0 1 1 1 1 Clr5 domain Ank_5 PF13857.6 ETS77149.1 - 8.8e-14 51.4 5.3 0.11 12.8 0.0 8.5 8 1 1 9 9 9 3 Ankyrin repeats (many copies) Ank PF00023.30 ETS77149.1 - 1.7e-09 37.7 9.6 0.012 16.1 0.1 8.3 9 0 0 9 9 9 2 Ankyrin repeat DUF2264 PF10022.9 ETS77150.1 - 1.1e-135 452.3 0.1 1.3e-135 452.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Aminotran_5 PF00266.19 ETS77151.1 - 2.1e-34 119.1 0.0 1.6e-22 80.0 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V adh_short PF00106.25 ETS77152.1 - 2.1e-21 76.3 0.0 3.7e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS77152.1 - 5.3e-17 62.2 0.0 8.2e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS77152.1 - 0.0034 17.3 0.0 0.012 15.5 0.0 1.8 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 ETS77152.1 - 0.034 13.5 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TRAPPC9-Trs120 PF08626.11 ETS77153.1 - 0 1402.2 0.0 0 1402.0 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit ASH PF15780.5 ETS77153.1 - 0.0056 16.8 0.2 0.026 14.7 0.1 2.2 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Longin PF13774.6 ETS77154.1 - 2.1e-24 85.4 0.1 3.2e-24 84.7 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 ETS77154.1 - 8.3e-15 54.4 0.1 1.7e-14 53.4 0.0 1.5 2 0 0 2 2 2 1 Synaptobrevin SLM4 PF16818.5 ETS77154.1 - 0.068 13.1 0.1 0.34 10.9 0.0 2.1 2 1 1 3 3 3 0 Protein SLM4 DUF1664 PF07889.12 ETS77154.1 - 0.11 12.5 0.0 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ASXH PF13919.6 ETS77155.1 - 4.6e-12 46.1 5.8 4.1e-11 43.1 5.8 2.4 1 1 0 1 1 1 1 Asx homology domain Spt20 PF12090.8 ETS77155.1 - 0.1 12.2 7.1 0.12 12.0 7.1 1.1 1 0 0 1 1 1 0 Spt20 family Asp PF00026.23 ETS77156.1 - 4e-49 167.7 0.0 6.5e-49 167.0 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS77156.1 - 5.5e-05 23.5 3.8 0.29 11.3 4.4 3.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ETS77156.1 - 8.5e-05 23.1 0.5 1.8 9.2 0.0 3.3 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 ETS77156.1 - 9.9e-05 22.2 0.1 0.12 12.2 0.0 2.8 2 1 1 3 3 3 2 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 ETS77156.1 - 0.023 15.2 0.0 6.8 7.3 0.0 3.0 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Elong_Iki1 PF10483.9 ETS77157.1 - 6e-100 334.6 0.0 7.1e-100 334.3 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Proteasome PF00227.26 ETS77158.1 - 1.4e-52 178.0 0.1 1.8e-52 177.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ETS77158.1 - 2.2e-11 43.2 0.2 3.6e-11 42.5 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps55 PF04133.14 ETS77159.1 - 1.9e-43 147.2 8.6 2.1e-43 147.0 8.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 ABC2_membrane_3 PF12698.7 ETS77159.1 - 1.9 7.5 10.6 2.5 7.1 10.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Lysine_decarbox PF03641.14 ETS77160.1 - 6.7e-30 103.9 0.1 8.9e-30 103.5 0.1 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 ETS77160.1 - 9.7e-08 31.8 1.8 4e-07 29.8 1.8 1.9 1 1 0 1 1 1 1 SLOG cluster4 family CLPTM1 PF05602.12 ETS77161.1 - 2.4e-157 524.4 0.0 2.9e-157 524.1 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PAS_9 PF13426.7 ETS77163.1 - 1.4e-14 54.2 0.0 2.1e-13 50.4 0.0 2.7 3 0 0 3 3 3 1 PAS domain Prothymosin PF03247.14 ETS77164.1 - 5.8 7.4 7.8 16 6.0 4.4 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family Acetyltransf_1 PF00583.25 ETS77165.1 - 4.2e-14 52.8 0.0 5.9e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS77165.1 - 7e-10 39.2 0.0 1.3e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS77165.1 - 1.8e-09 37.6 0.0 2.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS77165.1 - 2.5e-05 24.2 0.0 4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ETS77165.1 - 0.036 14.1 0.0 0.062 13.4 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1793 PF08760.11 ETS77166.1 - 8.7e-68 228.0 2.1 1.1e-67 227.7 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 ETS77166.1 - 8.4e-67 224.2 0.2 4.4e-53 179.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 ETS77166.1 - 4.2e-43 147.8 0.3 7.3e-43 147.0 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 ETS77166.1 - 0.00057 19.4 0.2 0.0035 16.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) Glyco_hydro_47 PF01532.20 ETS77169.1 - 8.4e-171 568.9 0.0 9.6e-171 568.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pec_lyase PF09492.10 ETS77169.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Pectic acid lyase RRM_1 PF00076.22 ETS77170.1 - 2.8e-19 68.7 0.0 3.9e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ETS77170.1 - 0.00041 20.0 0.0 0.00063 19.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_1 PF00175.21 ETS77172.1 - 2.6e-07 31.2 0.0 1.4e-06 28.9 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ETS77172.1 - 0.00038 20.6 0.0 0.016 15.4 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Helo_like_N PF17111.5 ETS77173.1 - 2.2e-35 121.9 5.8 3.3e-33 114.8 1.5 2.2 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins DUF3164 PF11363.8 ETS77173.1 - 0.0011 18.6 2.7 0.66 9.6 0.1 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF3164) DUF1993 PF09351.10 ETS77173.1 - 0.061 13.5 0.7 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Ank_2 PF12796.7 ETS77174.1 - 2.7e-13 50.3 0.4 2.3e-10 40.9 0.2 4.7 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS77174.1 - 1.3e-08 35.2 0.9 4.7e-06 27.0 0.1 4.3 2 1 2 4 4 4 2 Ankyrin repeats (many copies) NACHT PF05729.12 ETS77174.1 - 1.7e-08 34.5 0.1 4.6e-08 33.2 0.1 1.8 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.6 ETS77174.1 - 9.7e-07 28.6 1.1 0.048 14.2 0.1 5.3 6 0 0 6 6 3 1 Ankyrin repeat Ank_5 PF13857.6 ETS77174.1 - 2.2e-06 27.9 0.0 0.042 14.2 0.1 3.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS77174.1 - 1.3e-05 25.4 1.2 0.51 10.9 0.1 4.0 3 0 0 3 3 3 2 Ankyrin repeat AAA_16 PF13191.6 ETS77174.1 - 3.4e-05 24.3 0.0 0.00064 20.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS77174.1 - 0.00025 21.3 0.0 0.0025 18.1 0.0 2.6 2 1 1 3 3 3 1 AAA domain KAP_NTPase PF07693.14 ETS77174.1 - 0.0052 16.1 0.6 0.85 8.8 0.0 2.5 2 0 0 2 2 2 1 KAP family P-loop domain ABC_tran PF00005.27 ETS77174.1 - 0.0062 17.1 0.0 0.018 15.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_10 PF12846.7 ETS77174.1 - 0.0086 15.0 0.0 2.4 7.0 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain RNA_helicase PF00910.22 ETS77174.1 - 0.0096 16.3 0.1 0.043 14.2 0.0 2.1 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.23 ETS77174.1 - 0.054 13.6 0.1 0.16 12.0 0.0 1.9 2 0 0 2 2 1 0 50S ribosome-binding GTPase DUF2075 PF09848.9 ETS77174.1 - 0.081 12.1 0.2 0.87 8.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 ETS77174.1 - 0.086 13.3 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 ETS77174.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 ETS77174.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 ETS77174.1 - 0.15 12.6 0.1 0.6 10.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 ETS77174.1 - 0.19 11.0 0.0 0.44 9.9 0.0 1.5 1 0 0 1 1 1 0 KaiC Amino_oxidase PF01593.24 ETS77175.1 - 8.7e-24 84.6 1.0 2.8e-23 82.9 1.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ETS77175.1 - 0.022 15.0 0.0 0.057 13.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF918 PF06033.11 ETS77175.1 - 0.16 12.0 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) Ank_2 PF12796.7 ETS77176.1 - 1.1e-15 58.0 1.9 5.9e-13 49.2 0.4 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS77176.1 - 1.6e-11 44.4 0.5 1.2e-05 25.8 0.1 4.6 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 ETS77176.1 - 1e-10 41.5 0.6 0.01 16.2 0.1 4.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 ETS77176.1 - 7.5e-10 38.9 0.1 0.00064 20.0 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) PDE4_UCR PF18100.1 ETS77176.1 - 0.093 13.4 0.2 6.4 7.4 0.1 2.9 2 0 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) Methyltransf_23 PF13489.6 ETS77177.1 - 1.5e-07 31.4 0.0 2.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS77177.1 - 0.00014 22.5 0.0 0.00057 20.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS77177.1 - 0.0002 21.2 0.0 0.0025 17.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS77177.1 - 0.00045 20.8 0.0 0.00092 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS77177.1 - 0.0024 18.6 0.0 0.0062 17.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.16 ETS77178.1 - 1e-29 103.6 29.5 1e-29 103.6 29.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TauD PF02668.16 ETS77179.1 - 7.5e-42 144.0 0.1 9.7e-42 143.6 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Tautomerase_3 PF14832.6 ETS77180.1 - 9.5e-42 142.5 0.0 1.1e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme 4HBT_3 PF13622.6 ETS77181.1 - 1.5e-44 153.1 0.4 1.8e-44 152.9 0.4 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 ETS77181.1 - 0.0027 17.6 0.0 0.0087 15.9 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA thioesterase Lactamase_B PF00753.27 ETS77182.1 - 1.9e-16 60.7 0.0 3.2e-16 59.9 0.0 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS77182.1 - 6.5e-06 25.8 0.0 8.3e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PH PF00169.29 ETS77182.1 - 0.079 13.5 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 PH domain MafB19-deam PF14437.6 ETS77182.1 - 0.18 11.5 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 MafB19-like deaminase WD40 PF00400.32 ETS77183.1 - 2.3e-37 126.3 26.2 1.6e-08 35.1 0.8 9.5 7 2 2 9 9 9 7 WD domain, G-beta repeat NACHT PF05729.12 ETS77183.1 - 1.1e-22 80.7 0.1 2.2e-22 79.8 0.1 1.5 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 ETS77183.1 - 4.3e-21 75.0 1.4 0.016 15.5 0.0 7.5 3 2 5 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 ETS77183.1 - 1.2e-07 31.4 1.9 0.2 11.6 0.0 6.6 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 ETS77183.1 - 4.3e-05 22.6 2.7 0.066 12.2 0.1 4.1 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_19 PF13245.6 ETS77183.1 - 0.0041 17.4 0.0 0.01 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF2441 PF10386.9 ETS77183.1 - 0.069 13.1 0.0 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2441) Proteasome_A_N PF10584.9 ETS77183.1 - 8.3 6.2 8.6 40 4.0 0.1 4.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Ndufs5 PF10200.9 ETS77186.1 - 0.00094 19.4 0.0 0.0011 19.2 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa UPF0203 PF05254.12 ETS77186.1 - 0.044 14.0 0.4 0.069 13.4 0.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) COX6B PF02297.17 ETS77186.1 - 0.063 13.5 0.2 0.091 13.0 0.2 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb COX17 PF05051.13 ETS77186.1 - 0.072 13.5 0.4 0.12 12.7 0.4 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) DUF3128 PF11326.8 ETS77186.1 - 0.089 13.2 1.3 0.21 12.0 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Sec39 PF08314.11 ETS77187.1 - 1.2e-285 949.8 0.7 1.4e-285 949.6 0.7 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 DUF1996 PF09362.10 ETS77189.1 - 3.4e-82 275.9 0.2 5.5e-82 275.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) UBA PF00627.31 ETS77190.1 - 7.3e-05 22.6 0.0 0.0002 21.2 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain TPR_2 PF07719.17 ETS77190.1 - 0.00019 21.3 0.0 4.1 7.8 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 ETS77190.1 - 0.003 17.3 0.1 5.6 7.0 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 ETS77190.1 - 0.015 15.6 0.0 0.28 11.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF630 PF04783.12 ETS77190.1 - 0.1 12.8 1.3 0.28 11.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF630) DnaJ PF00226.31 ETS77190.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain Sugar_tr PF00083.24 ETS77192.1 - 3.2e-114 382.3 18.3 4e-114 382.0 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS77192.1 - 6.7e-24 84.5 24.5 3.7e-16 59.0 1.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ETS77192.1 - 4.5e-05 22.0 1.7 4.5e-05 22.0 1.7 1.8 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family UQ_con PF00179.26 ETS77193.1 - 1.1e-50 170.9 0.0 1.2e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TPR_17 PF13431.6 ETS77194.1 - 5.3e-06 26.5 0.4 0.013 15.8 0.1 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 ETS77194.1 - 3e-05 24.6 4.9 0.15 12.7 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 ETS77194.1 - 0.00021 20.9 3.0 0.0023 17.6 0.1 3.8 3 1 1 4 4 4 1 TPR repeat TPR_19 PF14559.6 ETS77194.1 - 0.019 15.4 3.6 1.8 9.1 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat UNC45-central PF11701.8 ETS77194.1 - 0.035 14.1 0.1 0.11 12.5 0.1 1.8 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central TPR_1 PF00515.28 ETS77194.1 - 0.051 13.4 0.1 2.7 8.0 0.2 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 ETS77194.1 - 1.7 9.7 10.9 5.5 8.1 0.1 5.0 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 ETS77194.1 - 2.3 8.5 4.7 36 4.8 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat HET PF06985.11 ETS77195.1 - 2.5e-30 105.8 2.7 4.7e-30 104.9 2.7 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Phage_pRha PF09669.10 ETS77195.1 - 0.082 13.5 0.1 8.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) NmrA PF05368.13 ETS77196.1 - 1.2e-13 51.1 0.1 1.9e-13 50.5 0.1 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS77196.1 - 1.1e-12 48.2 0.2 1.6e-12 47.7 0.2 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS77196.1 - 1.7e-07 30.9 0.6 6.2e-07 29.1 0.6 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ETS77196.1 - 0.0011 19.0 0.4 0.0016 18.3 0.4 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 ETS77196.1 - 0.0053 17.3 0.3 0.022 15.3 0.1 2.1 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 ETS77196.1 - 0.13 11.4 0.1 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF4875 PF16175.5 ETS77196.1 - 0.15 12.2 0.6 0.33 11.1 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) GDP_Man_Dehyd PF16363.5 ETS77196.1 - 0.18 11.2 0.4 1 8.7 0.2 2.2 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase stn_TNFRSF12A PF12191.8 ETS77197.1 - 0.027 14.7 0.1 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain MFS_1 PF07690.16 ETS77198.1 - 6.9e-23 81.1 45.3 1.3e-12 47.4 18.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 ETS77200.1 - 2.1e-47 161.8 3.3 3.3e-47 161.1 3.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA PF00004.29 ETS77200.1 - 3e-16 60.1 0.0 1.4e-15 57.9 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zn_clus PF00172.18 ETS77200.1 - 2.4e-07 30.7 7.8 4.9e-07 29.8 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_16 PF13191.6 ETS77200.1 - 0.00098 19.5 0.3 0.0092 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS77200.1 - 0.0016 18.7 0.5 0.015 15.5 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 ETS77200.1 - 0.041 13.9 0.0 0.33 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 ETS77200.1 - 0.061 13.0 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ETS77200.1 - 0.097 13.0 0.1 0.32 11.3 0.1 1.9 1 0 0 1 1 1 0 AAA domain DUF1349 PF07081.11 ETS77201.1 - 2.2e-25 89.4 0.0 2.9e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) ThiF PF00899.21 ETS77202.1 - 0.014 14.8 0.0 0.035 13.5 0.0 1.6 1 0 0 1 1 1 0 ThiF family Voldacs PF03517.13 ETS77203.1 - 4.6e-25 88.4 0.1 1e-24 87.3 0.1 1.6 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling GST_C_2 PF13410.6 ETS77204.1 - 0.14 12.2 2.6 0.3 11.1 2.6 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain EXS PF03124.14 ETS77205.1 - 3.1e-100 335.7 30.5 3.8e-100 335.4 30.5 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 ETS77205.1 - 3.3e-84 284.0 3.7 3.3e-84 284.0 3.7 2.0 2 0 0 2 2 2 1 SPX domain Glyco_hydro_18 PF00704.28 ETS77206.1 - 2.3e-12 47.3 0.0 5.5e-12 46.0 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 MS_channel PF00924.18 ETS77207.1 - 5.9e-22 78.2 1.5 1e-21 77.5 1.5 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel ABC2_membrane_2 PF12679.7 ETS77207.1 - 0.014 14.7 0.0 7.2 5.8 1.7 2.6 3 1 0 3 3 3 0 ABC-2 family transporter protein EF-hand_6 PF13405.6 ETS77207.1 - 0.032 14.2 0.2 0.42 10.7 0.3 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 ETS77207.1 - 0.1 13.1 0.0 0.36 11.3 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 ETS77207.1 - 0.31 10.7 1.1 0.79 9.4 1.1 1.8 1 0 0 1 1 1 0 EF hand DHHC PF01529.20 ETS77209.1 - 9.5e-38 129.3 10.9 9.5e-38 129.3 10.9 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase PI-PLC-X PF00388.19 ETS77211.1 - 2.7e-55 186.0 0.0 4.7e-55 185.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 ETS77211.1 - 9.5e-41 138.8 0.2 2.4e-40 137.5 0.2 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 ETS77211.1 - 2.7e-07 30.8 0.3 7.7e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 C2 domain PH PF00169.29 ETS77211.1 - 0.011 16.3 0.1 0.024 15.1 0.1 1.7 1 0 0 1 1 1 0 PH domain PH_12 PF16457.5 ETS77211.1 - 0.016 15.7 0.1 0.066 13.7 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Peptidase_S15 PF02129.18 ETS77212.1 - 2.2e-40 138.9 4.0 1.4e-37 129.8 1.8 2.7 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ETS77212.1 - 9.6e-25 87.8 0.7 2e-22 80.2 0.2 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 ETS77213.1 - 2.9e-37 128.7 0.0 4e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ETS77213.1 - 4e-31 108.7 0.0 6.4e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Zn_clus PF00172.18 ETS77214.1 - 5.4e-08 32.8 12.0 1.2e-07 31.8 12.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS77214.1 - 0.019 14.0 0.3 0.03 13.4 0.3 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Cep3 PF16846.5 ETS77214.1 - 0.02 13.4 0.1 0.041 12.4 0.1 1.4 1 1 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B TauD PF02668.16 ETS77215.1 - 2.3e-35 122.7 0.0 3e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.16 ETS77216.1 - 4.5e-47 161.1 0.2 5.3e-47 160.8 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Peptidase_C80 PF11713.8 ETS77216.1 - 0.043 14.1 0.1 0.065 13.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase C80 family ACT_3 PF10000.9 ETS77217.1 - 2.4e-21 75.4 0.0 3.5e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 ETS77217.1 - 1.2e-09 37.8 0.0 4.3e-09 36.0 0.0 1.9 3 0 0 3 3 3 1 ACT domain Ank_2 PF12796.7 ETS77218.1 - 5.8e-46 155.0 12.7 1e-12 48.4 0.0 6.5 3 2 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS77218.1 - 6.3e-38 128.7 5.4 6.2e-09 36.2 0.0 8.0 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 ETS77218.1 - 5.1e-31 105.7 4.2 0.0036 17.7 0.0 9.5 10 0 0 10 10 10 7 Ankyrin repeat Ank_3 PF13606.6 ETS77218.1 - 2.2e-26 89.0 3.7 0.0013 19.0 0.0 10.9 10 1 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 ETS77218.1 - 5.2e-25 87.2 6.6 2.2e-08 34.2 0.8 5.9 4 2 2 6 6 6 5 Ankyrin repeats (many copies) CorA PF01544.18 ETS77218.1 - 7.7e-13 48.4 3.2 2.3e-12 46.9 2.5 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1461 PF07314.11 ETS77218.1 - 1.2 9.0 4.7 10 5.9 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) Fungal_trans PF04082.18 ETS77220.1 - 7.5e-20 71.1 0.1 1.3e-19 70.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS77220.1 - 9.2e-09 35.3 9.9 2.4e-08 33.9 9.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GP3_package PF16677.5 ETS77220.1 - 0.0086 16.2 0.0 0.94 9.6 0.0 2.4 2 0 0 2 2 2 1 DNA-packaging protein gp3 DUF4995 PF16386.5 ETS77220.1 - 0.13 12.3 0.1 3.6 7.6 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function Acyl-CoA_dh_1 PF00441.24 ETS77221.1 - 3.7e-32 111.6 1.2 5.5e-32 111.0 1.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ETS77221.1 - 1.6e-21 76.3 0.1 2.9e-21 75.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ETS77221.1 - 7.6e-19 68.4 0.0 2.1e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ETS77221.1 - 1.6e-06 28.4 0.7 2.5e-06 27.8 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CPSase_L_D2 PF02786.17 ETS77222.1 - 8e-66 221.5 0.0 1.5e-65 220.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ETS77222.1 - 1.5e-40 138.2 0.0 4.4e-40 136.7 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ETS77222.1 - 6.9e-30 103.3 0.0 1.3e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ETS77222.1 - 7.9e-10 38.4 1.7 1.9e-09 37.2 1.7 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 ETS77222.1 - 4.8e-08 32.8 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 ETS77222.1 - 1.1e-06 28.8 0.0 2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ETS77222.1 - 3.9e-06 26.6 0.0 1.3e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus GCV_H PF01597.19 ETS77222.1 - 0.08 12.8 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein ATPgrasp_YheCD PF14398.6 ETS77222.1 - 0.14 11.4 0.0 4.1 6.6 0.0 2.3 2 0 0 2 2 2 0 YheC/D like ATP-grasp Carboxyl_trans PF01039.22 ETS77223.1 - 5.3e-116 388.2 0.0 6.7e-116 387.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain AMP-binding PF00501.28 ETS77224.1 - 1.3e-97 327.1 0.0 1.5e-97 326.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS77224.1 - 7e-12 46.1 0.0 1.6e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DRTGG PF07085.12 ETS77224.1 - 0.023 14.5 0.0 0.057 13.2 0.0 1.7 1 0 0 1 1 1 0 DRTGG domain HMGL-like PF00682.19 ETS77225.1 - 2.2e-41 142.2 0.0 2.9e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 HMGL-like ECH_1 PF00378.20 ETS77225.1 - 2.9e-36 125.1 0.0 4.3e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ETS77225.1 - 3.2e-24 86.1 0.0 4.4e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF3405 PF11885.8 ETS77227.1 - 2e-71 241.2 7.5 4e-70 236.9 7.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) SKG6 PF08693.10 ETS77228.1 - 0.0014 18.0 0.6 0.0035 16.7 0.6 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain PTP_tm PF18861.1 ETS77228.1 - 0.0087 16.1 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J VPDSG-CTERM PF18205.1 ETS77228.1 - 0.044 13.6 0.8 0.044 13.6 0.8 2.0 2 0 0 2 2 2 0 VPDSG-CTERM motif DUF4448 PF14610.6 ETS77228.1 - 0.087 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Adeno_PV PF03910.13 ETS77228.1 - 1 8.0 5.4 1.4 7.5 5.4 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV UbiD PF01977.16 ETS77229.1 - 1.3e-112 376.7 0.0 1.5e-112 376.5 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Flavoprotein PF02441.19 ETS77230.1 - 7.3e-23 81.1 0.0 9.4e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein GNVR PF13807.6 ETS77230.1 - 0.034 14.0 0.1 0.06 13.3 0.1 1.4 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase ABC_membrane PF00664.23 ETS77231.1 - 4.6e-50 170.8 9.3 6.3e-50 170.3 9.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ETS77231.1 - 5e-34 117.8 0.0 9.4e-33 113.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 ETS77231.1 - 4.5e-06 26.2 0.0 0.00022 20.7 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ETS77231.1 - 0.00025 21.3 0.4 0.0089 16.3 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS77231.1 - 0.0016 18.8 0.0 0.0078 16.6 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 ETS77231.1 - 0.0046 17.0 0.0 0.024 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 ETS77231.1 - 0.0069 16.8 0.9 0.069 13.6 0.1 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 ETS77231.1 - 0.021 14.6 0.3 0.61 9.8 0.0 2.6 2 1 1 3 3 3 0 IstB-like ATP binding protein AAA_29 PF13555.6 ETS77231.1 - 0.049 13.4 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 ETS77231.1 - 0.087 13.1 0.9 2.6 8.4 0.6 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 ETS77231.1 - 0.18 10.6 1.2 0.17 10.6 0.1 1.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Coilin_N PF15862.5 ETS77231.1 - 0.63 9.8 3.9 1.2 8.9 0.4 2.4 2 0 0 2 2 2 0 Coilin N-terminus Hydrolase_4 PF12146.8 ETS77232.1 - 1.6e-53 181.4 0.0 1.9e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS77232.1 - 3.4e-14 53.1 0.1 1.9e-13 50.7 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS77232.1 - 2.5e-12 47.9 0.5 3.1e-12 47.6 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ETS77232.1 - 0.012 15.0 0.1 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 ETS77232.1 - 0.049 13.5 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Thioesterase PF00975.20 ETS77232.1 - 0.053 13.6 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 ETS77232.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Adaptin_N PF01602.20 ETS77233.1 - 1.7e-145 485.6 6.1 2e-145 485.4 6.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 ETS77233.1 - 9.1e-20 71.0 0.0 2.1e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 ETS77233.1 - 7.2e-08 32.6 11.3 2.6e-05 24.3 0.0 4.6 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ETS77233.1 - 6.7e-05 23.2 0.8 0.62 10.5 0.0 3.8 3 1 0 3 3 3 2 HEAT repeats DUF3730 PF12530.8 ETS77233.1 - 0.00013 21.7 0.1 0.0039 16.8 0.1 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3730) RIX1 PF08167.12 ETS77233.1 - 0.013 15.3 0.1 0.32 10.7 0.0 3.0 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis HEAT PF02985.22 ETS77233.1 - 0.03 14.6 1.1 19 5.8 0.1 4.1 3 0 0 3 3 3 0 HEAT repeat NlpE PF04170.12 ETS77233.1 - 0.1 13.6 0.0 0.78 10.7 0.0 2.2 2 0 0 2 2 2 0 NlpE N-terminal domain zf-RING_12 PF17976.1 ETS77234.1 - 0.018 15.3 0.4 1.2 9.5 0.3 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Orn_Arg_deC_N PF02784.16 ETS77236.1 - 6.1e-84 281.2 0.0 8.1e-84 280.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 ETS77236.1 - 8.5e-18 64.4 0.0 2.6e-17 62.8 0.0 1.9 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 ETS77236.1 - 0.0012 18.3 0.0 0.0025 17.3 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Abhydrolase_3 PF07859.13 ETS77236.1 - 0.036 13.9 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold M16C_assoc PF08367.11 ETS77237.1 - 7.4e-81 271.0 0.2 1.2e-80 270.3 0.2 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 ETS77237.1 - 1.5e-33 116.3 0.0 1.3e-22 80.7 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ETS77237.1 - 3.4e-08 33.6 0.0 2.9e-07 30.6 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) UvrA_inter PF17760.1 ETS77237.1 - 0.021 14.9 1.0 0.041 14.0 0.1 1.9 2 0 0 2 2 2 0 UvrA interaction domain IlvC PF01450.19 ETS77237.1 - 0.17 12.2 1.1 2.4 8.5 0.2 2.9 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain Taxilin PF09728.9 ETS77238.1 - 9.5e-67 225.3 69.4 5.7e-65 219.5 63.1 3.5 1 1 1 2 2 2 1 Myosin-like coiled-coil protein CENP-F_leu_zip PF10473.9 ETS77238.1 - 0.00088 19.3 6.3 0.00088 19.3 6.3 4.2 3 1 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 ETS77238.1 - 0.0029 17.8 49.6 0.2 11.9 6.1 4.9 3 1 2 5 5 5 4 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 ETS77238.1 - 0.012 15.0 3.1 0.012 15.0 3.1 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3450) LTV PF04180.14 ETS77239.1 - 3.5e-118 395.7 17.3 3.9e-118 395.5 17.3 1.0 1 0 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.23 ETS77240.1 - 1.2e-16 60.8 0.4 4.2e-15 55.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ETS77240.1 - 7.3e-07 28.8 0.4 8.3e-06 25.4 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ETS77240.1 - 6.4e-06 26.2 0.2 0.0033 17.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 ETS77240.1 - 0.0082 15.5 0.1 0.017 14.5 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 ETS77240.1 - 0.079 13.0 0.1 0.079 13.0 0.1 2.7 3 0 0 3 3 3 0 Dynamin family Peptidase_S9 PF00326.21 ETS77241.1 - 6.1e-45 153.3 0.0 8.1e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ETS77241.1 - 1.7e-09 37.3 0.1 0.00025 20.4 0.0 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 PD40 PF07676.12 ETS77241.1 - 2.3e-09 37.0 2.5 0.00048 20.0 0.0 3.1 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DLH PF01738.18 ETS77241.1 - 7.2e-09 35.5 0.0 2e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 ETS77241.1 - 6.7e-07 29.4 0.0 3.7e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 ETS77241.1 - 9.9e-06 25.4 0.1 0.0069 16.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 ETS77241.1 - 1e-05 25.3 0.4 0.012 15.2 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 ETS77241.1 - 0.00086 18.1 0.0 0.013 14.2 0.0 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 ETS77241.1 - 0.0031 17.4 0.0 0.05 13.4 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 ETS77241.1 - 0.012 15.5 0.1 0.038 13.8 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 ETS77241.1 - 0.016 14.9 0.0 0.044 13.4 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_M14 PF00246.24 ETS77241.1 - 0.016 15.1 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Zinc carboxypeptidase DUF1749 PF08538.10 ETS77241.1 - 0.03 13.4 0.0 0.16 11.0 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) Abhydrolase_4 PF08386.10 ETS77241.1 - 0.03 14.4 0.0 0.092 12.9 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein Esterase_phd PF10503.9 ETS77241.1 - 0.056 12.9 0.1 0.16 11.4 0.1 1.7 1 1 0 1 1 1 0 Esterase PHB depolymerase LIP PF03583.14 ETS77241.1 - 0.1 11.9 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase HET PF06985.11 ETS77243.1 - 1.9e-27 96.4 0.0 3.7e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) IRK_N PF08466.10 ETS77244.1 - 0.0025 17.9 0.2 0.0099 16.0 0.0 2.1 2 0 0 2 2 2 1 Inward rectifier potassium channel N-terminal UNC-93 PF05978.16 ETS77246.1 - 7.8e-13 48.4 1.5 7.8e-13 48.4 1.5 2.3 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ETS77246.1 - 1.9e-12 46.8 27.2 1.9e-12 46.8 27.2 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily YadA_anchor PF03895.15 ETS77246.1 - 5.2 7.3 8.9 69 3.7 0.0 4.4 5 0 0 5 5 5 0 YadA-like membrane anchor domain LSM PF01423.22 ETS77247.1 - 6.6e-16 57.8 0.2 8.7e-16 57.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ETS77247.1 - 0.12 12.5 0.1 0.28 11.4 0.1 1.6 1 1 0 1 1 1 0 Ataxin 2 SM domain tRNA-synt_1b PF00579.25 ETS77248.1 - 9.6e-17 61.2 0.1 2e-16 60.2 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Pirin_C PF05726.13 ETS77248.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Pirin C-terminal cupin domain 2-Hacid_dh_C PF02826.19 ETS77250.1 - 3.8e-44 150.2 0.1 4.8e-29 101.0 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ETS77250.1 - 0.03 14.5 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 ETS77250.1 - 0.055 13.3 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ETS77250.1 - 0.055 12.8 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 ETS77250.1 - 0.091 13.3 0.0 0.17 12.4 0.0 1.5 1 1 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.17 ETS77250.1 - 0.12 13.0 0.0 0.24 12.0 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 ETS77250.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA tRNA-synt_1e PF01406.19 ETS77252.1 - 4.7e-115 384.1 0.0 7.2e-115 383.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 ETS77252.1 - 1.4e-06 27.4 0.8 0.019 13.7 0.1 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 ETS77252.1 - 0.0031 16.5 0.1 0.78 8.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1c PF00749.21 ETS77252.1 - 0.011 14.7 0.0 0.028 13.3 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Oxidored_FMN PF00724.20 ETS77253.1 - 2.9e-88 296.4 0.0 3.3e-88 296.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NAD_binding_10 PF13460.6 ETS77254.1 - 8.7e-18 64.9 0.0 1.4e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS77254.1 - 2e-11 43.9 0.0 2.7e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 ETS77254.1 - 0.019 14.0 0.1 0.033 13.2 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 ETS77254.1 - 0.15 12.2 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF3970 PF13113.6 ETS77254.1 - 0.25 11.6 1.6 0.6 10.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) Esterase_phd PF10503.9 ETS77255.1 - 2.1e-17 63.4 0.9 2.9e-17 62.9 0.9 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ETS77255.1 - 1.1e-09 38.1 1.3 1.7e-09 37.4 0.7 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 ETS77255.1 - 1.5e-07 31.4 1.2 1.9e-07 31.0 1.2 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 ETS77255.1 - 0.006 16.5 0.1 0.0094 15.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold INCENP_ARK-bind PF03941.15 ETS77255.1 - 0.079 12.9 0.0 0.53 10.3 0.0 2.1 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region PEP_mutase PF13714.6 ETS77256.1 - 8.6e-52 176.0 0.4 1e-51 175.7 0.4 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 ETS77256.1 - 1.8e-11 43.2 0.1 2.6e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 ETS77256.1 - 0.001 18.5 0.1 0.016 14.6 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate hydroxymethyltransferase DAHP_synth_1 PF00793.20 ETS77256.1 - 0.11 11.3 0.0 0.28 10.0 0.0 1.6 1 0 0 1 1 1 0 DAHP synthetase I family FMO-like PF00743.19 ETS77257.1 - 3.7e-13 48.8 0.0 5.8e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ETS77257.1 - 8.4e-10 38.3 0.0 3.2e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS77257.1 - 5.9e-09 35.6 0.0 1.4e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS77257.1 - 1.7e-08 34.6 0.0 3.7e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ETS77257.1 - 2.7e-06 26.8 0.0 0.00014 21.1 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 ETS77257.1 - 9.3e-06 25.1 0.1 0.079 12.2 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 ETS77257.1 - 8.6e-05 21.7 0.0 0.00036 19.7 0.0 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ETS77257.1 - 0.0026 16.9 0.1 0.0061 15.7 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 ETS77257.1 - 0.0073 15.7 0.7 0.015 14.7 0.7 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ETS77257.1 - 0.014 14.5 0.3 0.26 10.3 0.1 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 ETS77257.1 - 0.025 14.6 3.7 0.26 11.3 0.4 3.2 3 1 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 ETS77257.1 - 0.046 13.0 0.4 0.12 11.6 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 ETS77257.1 - 0.067 13.8 0.2 2.4 8.8 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 ETS77257.1 - 0.12 11.8 0.7 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 ETS77257.1 - 0.18 11.3 1.1 29 4.1 0.2 3.1 3 1 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS77257.1 - 0.22 10.2 0.7 0.73 8.5 0.5 1.8 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.20 ETS77257.1 - 0.42 10.7 1.0 14 5.7 0.0 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 ETS77258.1 - 3.9e-32 111.9 0.0 8.3e-32 110.8 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 ETS77258.1 - 2.4e-07 30.4 0.2 0.0053 16.1 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 ETS77258.1 - 2.9e-07 30.1 0.3 2.4e-05 23.8 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS77258.1 - 1.7e-05 25.0 0.2 4.1e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS77258.1 - 2.2e-05 23.8 0.1 0.0016 17.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS77258.1 - 0.00058 19.1 0.2 0.00097 18.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS77258.1 - 0.00066 19.4 2.1 0.002 17.7 1.8 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ETS77258.1 - 0.00073 18.7 1.2 0.069 12.2 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 ETS77258.1 - 0.00093 18.5 0.0 0.0021 17.3 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 ETS77258.1 - 0.0016 19.0 0.6 0.0077 16.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS77258.1 - 0.0024 16.7 0.2 0.015 14.0 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 ETS77258.1 - 0.0072 15.2 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_7 PF13241.6 ETS77258.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 ETS77258.1 - 0.015 14.4 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 ETS77258.1 - 0.071 12.4 0.7 0.21 10.9 0.7 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 ETS77258.1 - 0.089 13.1 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain SE PF08491.10 ETS77258.1 - 0.096 11.7 0.0 0.8 8.7 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase DUF1382 PF07131.11 ETS77258.1 - 0.19 11.8 0.2 0.43 10.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) NAD_binding_9 PF13454.6 ETS77258.1 - 1.2 9.1 4.4 20 5.1 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding COesterase PF00135.28 ETS77259.1 - 2.8e-88 297.0 0.1 1.2e-87 295.0 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS77259.1 - 0.00053 19.9 0.5 0.0018 18.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Tannase PF07519.11 ETS77261.1 - 1.3e-92 311.1 2.3 1.6e-92 310.9 2.3 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase DUF2733 PF10813.8 ETS77261.1 - 0.024 14.4 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) FSH1 PF03959.13 ETS77261.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 ETS77261.1 - 0.14 11.4 0.0 2.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Clr5 PF14420.6 ETS77263.1 - 3.2e-08 33.7 0.1 4.7e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 Clr5 domain Methyltransf_2 PF00891.18 ETS77264.1 - 3.2e-20 72.3 0.0 9.2e-20 70.8 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase domain HET PF06985.11 ETS77265.1 - 1.9e-24 86.7 1.9 1e-21 77.8 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AXE1 PF05448.12 ETS77266.1 - 0.14 10.8 0.1 0.31 9.7 0.1 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) zf-RING_9 PF13901.6 ETS77267.1 - 0.031 14.3 0.2 0.076 13.0 0.1 1.7 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon Spc7 PF08317.11 ETS77267.1 - 0.06 12.2 1.0 0.1 11.5 1.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ChitinaseA_N PF08329.10 ETS77267.1 - 0.077 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Chitinase A, N-terminal domain HTH_29 PF13551.6 ETS77267.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Helo_like_N PF17111.5 ETS77267.1 - 1.5 8.2 4.7 0.47 9.8 0.4 2.1 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins SGL PF08450.12 ETS77268.1 - 1.5e-06 28.0 0.0 0.0012 18.4 0.0 3.1 2 1 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 ETS77268.1 - 0.0058 16.6 0.2 0.023 14.7 0.2 2.1 1 0 0 1 1 1 1 Beta-propeller repeat NHL PF01436.21 ETS77268.1 - 4.2 7.6 10.5 35 4.7 0.1 4.5 6 0 0 6 6 6 0 NHL repeat Cu_amine_oxid PF01179.20 ETS77269.1 - 6.8e-161 535.8 0.0 8.2e-161 535.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 ETS77269.1 - 0.023 15.1 0.0 0.11 12.9 0.0 2.1 2 0 0 2 2 2 0 Copper amine oxidase, N3 domain Aa_trans PF01490.18 ETS77270.1 - 3.8e-24 85.2 32.2 4.3e-24 85.0 32.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.21 ETS77270.1 - 1.4e-05 23.9 19.9 1.4e-05 23.9 19.9 2.1 2 0 0 2 2 2 1 Amino acid permease Myb_DNA-binding PF00249.31 ETS77271.1 - 4.1e-32 110.1 4.3 3.5e-12 46.3 0.3 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ETS77271.1 - 2.6e-27 94.8 2.3 1.9e-12 47.2 0.1 4.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 ETS77271.1 - 6.1e-05 23.0 0.0 0.64 10.1 0.0 3.4 2 1 1 3 3 3 1 SLIDE SANT_DAMP1_like PF16282.5 ETS77271.1 - 0.0024 18.0 0.0 5.9 7.2 0.0 3.1 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 ETS77271.1 - 0.026 14.6 0.0 1.6 8.9 0.0 2.6 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF5133 PF17196.4 ETS77271.1 - 0.43 10.8 0.1 0.43 10.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) GDP_Man_Dehyd PF16363.5 ETS77272.1 - 0.00012 21.6 0.0 0.00013 21.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ETS77272.1 - 0.00088 18.9 0.0 0.0009 18.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ETS77272.1 - 0.0015 18.0 0.0 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 ETS77272.1 - 0.011 15.2 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase FmdA_AmdA PF03069.15 ETS77273.1 - 3.3e-114 381.6 0.0 3.9e-114 381.4 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family CorA PF01544.18 ETS77276.1 - 1e-06 28.3 0.2 1.7e-06 27.6 0.2 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SH3BP5 PF05276.14 ETS77276.1 - 0.031 14.1 0.0 0.044 13.6 0.0 1.1 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) DUF892 PF05974.12 ETS77276.1 - 0.093 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Ank_2 PF12796.7 ETS77277.1 - 4.3e-131 427.8 0.1 3.4e-19 69.2 0.0 12.5 3 3 9 12 12 12 12 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS77277.1 - 6.6e-107 336.4 0.0 3.5e-05 23.9 0.0 23.1 22 1 1 23 23 23 19 Ankyrin repeat Ank_4 PF13637.6 ETS77277.1 - 8.7e-101 329.1 3.7 2e-11 44.2 0.0 15.9 6 4 10 17 17 17 17 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS77277.1 - 1.7e-96 315.0 2.0 4e-08 33.4 0.0 18.7 7 4 11 18 18 18 18 Ankyrin repeats (many copies) Ank PF00023.30 ETS77277.1 - 1.5e-90 294.0 8.2 4.2e-05 23.8 0.0 22.0 22 0 0 22 22 22 19 Ankyrin repeat PEGA PF08308.11 ETS77277.1 - 0.11 12.4 0.0 81 3.2 0.0 4.8 5 0 0 5 5 5 0 PEGA domain CholecysA-Rec_N PF09193.10 ETS77277.1 - 0.22 11.5 0.6 4.6 7.3 0.1 3.5 4 0 0 4 4 4 0 Cholecystokinin A receptor, N-terminal MGC-24 PF05283.11 ETS77278.1 - 0.059 13.8 11.0 0.11 12.9 11.0 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PAP1 PF08601.10 ETS77278.1 - 0.71 9.5 8.1 0.8 9.4 8.1 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 SSP160 PF06933.11 ETS77278.1 - 2.1 6.5 26.2 3 5.9 26.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Macoilin PF09726.9 ETS77278.1 - 7.5 5.0 6.0 9.1 4.7 6.0 1.1 1 0 0 1 1 1 0 Macoilin family Hamartin PF04388.12 ETS77278.1 - 8.4 4.9 6.9 10 4.7 6.9 1.0 1 0 0 1 1 1 0 Hamartin protein Beta-lactamase PF00144.24 ETS77279.1 - 2.9e-44 151.7 1.2 1e-43 149.8 1.2 1.6 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 ETS77279.1 - 0.012 15.2 0.4 0.12 12.0 0.0 2.2 2 1 0 2 2 2 0 Beta-lactamase enzyme family Glycos_transf_1 PF00534.20 ETS77280.1 - 1.2e-14 54.3 0.0 2.2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ETS77280.1 - 1.1e-13 51.8 0.0 2.2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 ETS77280.1 - 0.0041 16.9 0.0 0.012 15.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3492) Spherulin4 PF12138.8 ETS77281.1 - 1.8e-69 234.0 4.8 2.1e-69 233.8 4.8 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 SCAMP PF04144.13 ETS77281.1 - 0.011 16.0 0.3 0.016 15.5 0.3 1.2 1 0 0 1 1 1 0 SCAMP family DUF3792 PF12670.7 ETS77281.1 - 0.014 15.6 0.3 0.022 14.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) DUF3902 PF13042.6 ETS77281.1 - 0.017 14.7 0.4 0.028 14.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) TerC PF03741.16 ETS77281.1 - 0.034 13.8 0.1 0.045 13.4 0.1 1.2 1 0 0 1 1 1 0 Integral membrane protein TerC family Phage_tail_2 PF06199.11 ETS77281.1 - 0.035 14.2 0.0 0.13 12.4 0.1 1.9 2 0 0 2 2 2 0 Phage tail tube protein Flp1_like PF16982.5 ETS77281.1 - 0.29 10.6 3.6 0.66 9.4 3.6 1.5 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain Spherulin4 PF12138.8 ETS77282.1 - 7.2e-57 192.8 0.0 8.1e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 TrmB PF01978.19 ETS77282.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Epimerase PF01370.21 ETS77283.1 - 1.1e-36 126.5 0.0 2e-35 122.4 0.0 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS77283.1 - 1.1e-34 120.4 0.0 1.4e-33 116.7 0.0 2.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ETS77283.1 - 1.8e-08 33.8 0.0 2e-07 30.4 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ETS77283.1 - 3e-05 23.3 0.0 0.00013 21.2 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 ETS77283.1 - 3.1e-05 23.9 0.0 6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 ETS77283.1 - 5.2e-05 22.4 0.0 0.00033 19.8 0.0 2.3 3 1 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 ETS77283.1 - 0.0022 17.5 0.0 0.004 16.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Sua5_yciO_yrdC PF01300.18 ETS77284.1 - 0.048 13.2 0.0 0.067 12.7 0.0 1.1 1 0 0 1 1 1 0 Telomere recombination NAD_binding_4 PF07993.12 ETS77286.1 - 3e-26 92.2 0.0 4.4e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 ETS77286.1 - 3.8e-18 65.3 0.0 1.4e-17 63.5 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 ETS77286.1 - 4.1e-11 42.8 0.0 7.2e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 ETS77286.1 - 9.7e-06 25.9 0.0 3.2e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 ETS77286.1 - 0.0041 16.6 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 ETS77286.1 - 0.064 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DLH PF01738.18 ETS77287.1 - 2.9e-18 66.2 0.0 8.9e-18 64.6 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Asp PF00026.23 ETS77288.1 - 1e-28 100.7 2.7 2e-27 96.5 2.7 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS77288.1 - 0.00012 22.3 0.5 0.00012 22.3 0.5 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TNFR_16_TM PF18422.1 ETS77288.1 - 0.039 13.9 0.1 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Dehydrin PF00257.19 ETS77288.1 - 0.31 11.6 3.6 0.93 10.0 3.6 1.8 1 0 0 1 1 1 0 Dehydrin Glyco_hydro_42 PF02449.15 ETS77289.1 - 6.4e-110 368.0 8.3 9.2e-110 367.5 8.3 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_42M PF08532.10 ETS77289.1 - 2.7e-22 79.3 0.0 4.6e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain DUF4434 PF14488.6 ETS77289.1 - 3.1e-05 24.1 1.1 0.00042 20.4 1.1 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4434) Cellulase PF00150.18 ETS77289.1 - 8.8e-05 22.1 2.6 0.0003 20.3 1.6 2.0 1 1 1 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_14 PF01373.17 ETS77289.1 - 0.017 14.1 0.1 0.29 10.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 14 RHS PF03527.14 ETS77289.1 - 0.096 12.5 0.0 0.85 9.4 0.0 2.5 2 0 0 2 2 2 0 RHS protein FAD_binding_3 PF01494.19 ETS77290.1 - 6.5e-15 55.2 0.1 6.2e-09 35.5 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS77290.1 - 0.00021 21.4 0.1 0.00048 20.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 ETS77290.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.24 ETS77290.1 - 0.037 13.6 0.1 0.065 12.8 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS77290.1 - 0.042 13.1 0.1 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 ETS77290.1 - 0.068 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 ETS77290.1 - 0.13 11.3 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain RRG8 PF17068.5 ETS77291.1 - 0.011 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial CLP_protease PF00574.23 ETS77292.1 - 4.4e-68 228.8 0.0 5.6e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.16 ETS77292.1 - 0.009 15.0 0.1 0.02 13.9 0.0 1.5 2 0 0 2 2 2 1 Serine dehydrogenase proteinase ECH_1 PF00378.20 ETS77292.1 - 0.18 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ATG16 PF08614.11 ETS77295.1 - 0.0014 18.9 1.4 0.0014 18.9 1.4 1.9 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) GIT_CC PF16559.5 ETS77295.1 - 0.01 15.6 1.8 0.01 15.6 1.8 3.0 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor CCDC144C PF14915.6 ETS77295.1 - 0.012 14.8 1.0 0.022 13.9 1.0 1.4 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region MscS_porin PF12795.7 ETS77295.1 - 0.018 14.6 2.9 0.018 14.6 0.8 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Tropomyosin PF00261.20 ETS77295.1 - 0.024 14.0 0.9 0.044 13.1 0.9 1.4 1 0 0 1 1 1 0 Tropomyosin DUF4349 PF14257.6 ETS77295.1 - 0.027 13.9 0.3 0.063 12.7 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF812 PF05667.11 ETS77295.1 - 0.042 12.7 1.0 0.051 12.5 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) HAP1_N PF04849.13 ETS77295.1 - 0.051 12.8 5.5 0.036 13.3 3.2 1.7 1 1 0 2 2 2 0 HAP1 N-terminal conserved region APG6_N PF17675.1 ETS77295.1 - 0.11 13.0 1.8 0.24 11.9 1.3 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 ETS77295.1 - 0.17 11.9 3.9 0.064 13.3 0.8 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GrpE PF01025.19 ETS77295.1 - 0.24 11.0 2.8 0.36 10.5 2.1 1.6 1 1 0 1 1 1 0 GrpE GAS PF13851.6 ETS77295.1 - 0.41 10.0 4.8 0.56 9.5 4.1 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4315 PF14193.6 ETS77295.1 - 1.5 8.9 4.2 1.9 8.6 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) Clr5 PF14420.6 ETS77297.1 - 4.6e-19 68.4 3.5 1.3e-18 67.0 0.6 2.7 2 1 0 2 2 2 1 Clr5 domain Promethin PF16015.5 ETS77298.1 - 1.2e-34 118.4 12.3 1.4e-34 118.2 12.3 1.1 1 0 0 1 1 1 1 Promethin VIT1 PF01988.19 ETS77298.1 - 4.4 7.1 7.5 6.8 6.5 7.5 1.4 1 1 0 1 1 1 0 VIT family DAO PF01266.24 ETS77299.1 - 2e-52 179.0 1.4 2.3e-52 178.7 1.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS77299.1 - 0.00013 22.2 0.8 0.00031 20.9 0.3 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS77299.1 - 0.0025 17.1 0.0 0.18 11.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS77299.1 - 0.0029 16.9 0.0 0.005 16.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 ETS77299.1 - 0.0077 15.4 1.7 0.021 13.9 1.6 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ETS77299.1 - 0.0096 15.2 0.0 0.27 10.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS77299.1 - 0.12 12.4 0.0 0.8 9.7 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Glyco_hydro_76 PF03663.14 ETS77300.1 - 3.6e-114 382.1 8.2 4.1e-114 381.9 8.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 F-box-like PF12937.7 ETS77301.1 - 0.00031 20.6 0.2 0.00067 19.5 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS77301.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 F-box domain BAR PF03114.18 ETS77303.1 - 1.8e-66 224.2 3.4 2.1e-66 224.0 3.4 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 ETS77303.1 - 0.0073 17.0 0.8 0.022 15.5 0.0 2.3 3 1 1 4 4 4 1 CP12 domain SVIP PF15811.5 ETS77303.1 - 1.7 9.2 4.7 0.52 10.8 0.7 2.2 2 1 0 2 2 2 0 Small VCP/p97-interacting protein Pept_tRNA_hydro PF01195.19 ETS77304.1 - 1e-24 87.4 0.0 1.2e-24 87.2 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase TauD PF02668.16 ETS77305.1 - 1.2e-48 166.3 1.0 1.4e-48 166.0 1.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3830 PF12903.7 ETS77306.1 - 1.1e-26 93.3 0.0 1.3e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3830) Zn_clus PF00172.18 ETS77307.1 - 0.0005 20.1 8.1 0.00086 19.4 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS77307.1 - 0.058 12.4 0.1 0.058 12.4 0.1 1.9 2 0 0 2 2 2 0 Fungal specific transcription factor domain AA_permease PF00324.21 ETS77308.1 - 1.2e-118 396.8 45.7 1.5e-118 396.5 45.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS77308.1 - 1.6e-32 112.9 49.4 1.8e-32 112.7 49.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4231 PF14015.6 ETS77308.1 - 0.087 13.3 0.0 0.087 13.3 0.0 4.2 5 1 1 6 6 6 0 Protein of unknown function (DUF4231) DHDPS PF00701.22 ETS77309.1 - 1.2e-27 96.4 0.0 1.8e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family HpcH_HpaI PF03328.14 ETS77310.1 - 2.1e-30 105.5 0.0 3e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family EamA PF00892.20 ETS77311.1 - 0.013 15.7 32.0 0.018 15.2 8.6 2.3 2 0 0 2 2 2 0 EamA-like transporter family Pkinase PF00069.25 ETS77312.1 - 5.9e-44 150.4 0.0 6.3e-43 147.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS77312.1 - 2.1e-29 102.6 0.0 2.8e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ETS77312.1 - 0.0012 17.7 0.0 0.0024 16.7 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ETS77312.1 - 0.19 11.0 0.0 15 4.8 0.1 2.3 2 0 0 2 2 2 0 Kinase-like FMO-like PF00743.19 ETS77313.1 - 9.8e-10 37.5 0.0 9.1e-09 34.3 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ETS77313.1 - 3.5e-09 36.3 0.0 7.4e-08 31.9 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ETS77313.1 - 1.6e-07 31.4 0.0 3.4e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS77313.1 - 5.5e-07 29.1 0.0 2.1e-06 27.2 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS77313.1 - 4.4e-06 26.1 0.0 0.0049 16.1 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS77313.1 - 0.0037 17.3 0.2 0.1 12.5 0.0 3.0 2 1 1 3 3 3 1 FAD-NAD(P)-binding Amidoligase_2 PF12224.8 ETS77314.1 - 7.5e-09 35.6 0.2 8.3e-06 25.6 0.0 2.5 3 0 0 3 3 3 2 Putative amidoligase enzyme DUF346 PF03984.13 ETS77314.1 - 0.028 14.2 0.4 0.063 13.0 0.4 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) MBOAT PF03062.19 ETS77316.1 - 8.9e-41 140.4 20.0 7.7e-39 134.0 20.0 2.1 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DnaJ PF00226.31 ETS77317.1 - 3.8e-20 71.8 1.8 1e-19 70.4 1.8 1.8 1 0 0 1 1 1 1 DnaJ domain SabA_adhesion PF18304.1 ETS77317.1 - 0.014 14.6 0.0 0.014 14.6 0.0 1.6 2 0 0 2 2 2 0 SabA N-terminal extracellular adhesion domain ADH_zinc_N PF00107.26 ETS77319.1 - 2.2e-22 79.4 0.0 3.4e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS77319.1 - 1.5e-21 76.3 1.5 2.4e-21 75.7 1.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ETS77319.1 - 2.7e-06 28.5 0.0 4.7e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ETS77319.1 - 0.00079 18.8 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ETS77319.1 - 0.0019 17.6 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 ETS77320.1 - 2.6e-27 95.5 0.1 4e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS77320.1 - 1.5e-16 60.7 2.7 7.6e-16 58.4 2.7 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS77320.1 - 3.2e-07 30.4 2.0 4e-05 23.6 0.4 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 ETS77320.1 - 0.00017 21.2 0.1 0.06 12.8 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS77320.1 - 0.0015 18.4 0.7 0.0028 17.6 0.4 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 ETS77320.1 - 0.0018 18.3 0.0 0.003 17.6 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DFP PF04127.15 ETS77320.1 - 0.014 15.2 0.1 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.8 ETS77320.1 - 0.048 13.4 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.19 ETS77320.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.26 ETS77320.1 - 0.11 12.4 0.7 0.18 11.8 0.7 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Kdo PF06293.14 ETS77321.1 - 3.1e-08 33.2 0.0 4.6e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 ETS77321.1 - 2.1e-05 24.0 0.0 2.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 ETS77321.1 - 0.00011 22.2 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETS77321.1 - 0.0028 17.3 0.0 0.12 11.9 0.0 2.1 1 1 1 2 2 2 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 ETS77321.1 - 0.015 14.3 0.0 0.037 13.0 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 ETS77321.1 - 0.037 13.7 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 EcKinase PF02958.20 ETS77321.1 - 0.051 12.9 0.0 0.066 12.5 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 ETS77321.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family HSP90 PF00183.18 ETS77322.1 - 3.6e-222 738.9 28.8 4.7e-222 738.5 28.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 ETS77322.1 - 5.6e-15 55.8 0.1 1e-14 55.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ETS77322.1 - 2.3e-11 43.7 0.1 9.1e-11 41.7 0.1 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 ETS77322.1 - 0.036 14.1 0.3 0.14 12.1 0.3 2.0 1 0 0 1 1 1 0 Tumour suppressor protein UPF0113_N PF17833.1 ETS77322.1 - 0.11 13.1 4.4 1.2 9.8 0.0 3.8 4 0 0 4 4 4 0 UPF0113 Pre-PUA domain AA_permease_2 PF13520.6 ETS77323.1 - 7.7e-20 71.1 11.7 8.9e-20 70.9 11.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS77323.1 - 1.5e-08 33.7 14.4 2.6e-08 32.9 14.4 1.3 1 1 0 1 1 1 1 Amino acid permease Deltameth_res PF16020.5 ETS77323.1 - 4.7 7.2 5.5 4.8 7.1 0.4 2.8 2 1 0 2 2 2 0 Deltamethrin resistance AA_permease_2 PF13520.6 ETS77324.1 - 1.3e-07 30.8 4.8 1.5e-07 30.6 4.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS77324.1 - 1.4e-05 23.9 2.2 1.6e-05 23.7 2.2 1.0 1 0 0 1 1 1 1 Amino acid permease SpoVAB PF13782.6 ETS77324.1 - 0.092 13.0 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AB DUF4611 PF15387.6 ETS77325.1 - 0.027 14.7 0.4 0.035 14.3 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) FMN_dh PF01070.18 ETS77327.1 - 2.2e-84 283.5 0.0 1.3e-44 152.6 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Peptidase_M19 PF01244.21 ETS77327.1 - 0.001 18.3 0.0 0.0024 17.1 0.0 1.5 2 0 0 2 2 2 1 Membrane dipeptidase (Peptidase family M19) IMPDH PF00478.25 ETS77327.1 - 0.097 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain ANAPC5 PF12862.7 ETS77328.1 - 0.14 12.3 1.2 0.88 9.7 0.1 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 Methyltransf_11 PF08241.12 ETS77329.1 - 0.00071 20.2 0.0 0.0015 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS77329.1 - 0.0039 17.0 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS77329.1 - 0.0053 17.5 0.0 0.0092 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 ETS77329.1 - 0.0096 15.4 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.6 ETS77329.1 - 0.023 15.4 0.0 0.052 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ferritin_2 PF13668.6 ETS77331.1 - 2.9e-45 153.8 2.6 3.8e-45 153.4 2.6 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF455 PF04305.14 ETS77331.1 - 0.21 11.1 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF455) NOB1_Zn_bind PF08772.11 ETS77332.1 - 3e-33 113.8 2.9 5.1e-33 113.1 2.9 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 ETS77332.1 - 1.3e-30 105.7 0.1 4.3e-30 104.1 0.0 1.9 2 0 0 2 2 2 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 ETS77332.1 - 0.016 14.8 4.3 0.021 14.5 0.7 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain HypA PF01155.19 ETS77332.1 - 0.072 13.1 0.1 0.37 10.8 0.2 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 ETS77332.1 - 0.36 11.0 3.0 0.46 10.6 1.5 2.0 2 0 0 2 2 2 0 Zinc ribbon domain Nop10p PF04135.12 ETS77333.1 - 5.8e-20 71.1 0.1 7.2e-20 70.8 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Oxidored_FMN PF00724.20 ETS77334.1 - 1.6e-96 323.6 0.0 1.9e-96 323.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 ETS77334.1 - 0.0029 17.1 0.0 2.5 7.5 0.0 2.3 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel CAP160 PF07918.11 ETS77334.1 - 3.9 7.3 5.2 0.47 10.2 0.6 1.9 2 0 0 2 2 2 0 CAP160 repeat GMC_oxred_N PF00732.19 ETS77335.1 - 1.3e-44 152.8 0.6 2e-42 145.6 0.1 2.3 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS77335.1 - 5.6e-27 95.0 0.6 1.6e-26 93.6 0.1 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS77335.1 - 6.2e-06 25.5 0.2 1.3e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS77335.1 - 3.9e-05 23.0 0.1 0.00012 21.4 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS77335.1 - 4.8e-05 23.5 1.2 0.00018 21.7 1.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ETS77335.1 - 0.00015 21.2 0.6 0.00032 20.1 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS77335.1 - 0.0011 18.6 1.3 0.17 11.4 0.4 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS77335.1 - 0.0026 16.6 0.5 0.0054 15.5 0.5 1.5 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 ETS77335.1 - 0.0043 16.3 0.1 0.0097 15.2 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 ETS77335.1 - 0.0087 15.4 1.3 0.038 13.3 1.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS77335.1 - 0.14 12.7 1.6 0.41 11.2 1.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS77335.1 - 0.34 10.1 0.8 2.3 7.4 0.8 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ETS77336.1 - 1.5e-16 59.9 0.0 6.2e-16 57.9 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ETS77336.1 - 2.4e-12 46.8 0.0 4.5e-12 45.8 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS77336.1 - 5.8e-12 45.7 0.0 1e-09 38.4 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS77336.1 - 5.1e-10 39.0 0.0 1.2e-07 31.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS77336.1 - 1.3e-09 38.1 0.4 0.00034 20.3 0.0 3.1 2 1 0 3 3 3 3 FAD dependent oxidoreductase Thi4 PF01946.17 ETS77336.1 - 1.9e-09 37.1 0.0 2e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 ETS77336.1 - 1.5e-06 27.6 0.0 0.0013 17.9 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 ETS77336.1 - 3.1e-05 23.2 1.0 0.044 12.8 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein Mqo PF06039.15 ETS77336.1 - 0.00084 18.0 0.0 0.9 8.0 0.0 2.8 2 1 1 3 3 3 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 ETS77336.1 - 0.0021 18.5 0.0 1.2 9.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS77336.1 - 0.0085 16.1 0.2 0.55 10.2 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ETS77336.1 - 0.018 14.2 0.0 0.068 12.2 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 ETS77336.1 - 0.064 13.7 0.0 0.13 12.7 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 ETS77336.1 - 0.12 12.5 0.0 0.61 10.2 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 ETS77336.1 - 0.22 10.2 0.0 1 8.0 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Abhydrolase_3 PF07859.13 ETS77337.1 - 1.9e-24 86.7 0.0 2.6e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS77337.1 - 8.1e-18 64.4 0.0 2.5e-17 62.8 0.0 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 ETS77337.1 - 2.8e-05 24.8 0.3 2.8e-05 24.8 0.3 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.28 ETS77337.1 - 0.0047 15.9 0.2 0.0095 14.8 0.2 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ETS77337.1 - 0.05 13.1 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family AMP-binding PF00501.28 ETS77338.1 - 3.8e-85 286.0 0.0 4.6e-85 285.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS77338.1 - 2.1e-26 92.7 0.2 4.6e-24 85.2 0.4 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 ETS77338.1 - 2.3e-19 69.0 1.1 1.4e-18 66.5 0.4 2.5 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus DNA_pol3_delta2 PF13177.6 ETS77339.1 - 3.9e-11 43.0 0.0 7.4e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 ETS77339.1 - 1.4e-06 28.8 0.0 3.3e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS77339.1 - 6.9e-06 26.4 0.1 0.0001 22.6 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS77339.1 - 0.00027 21.4 0.5 0.0044 17.4 0.3 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 ETS77339.1 - 0.00063 19.5 0.3 0.0017 18.1 0.3 1.7 1 1 0 1 1 1 1 AAA domain Rep_fac_C PF08542.11 ETS77339.1 - 0.0028 18.0 0.0 0.0095 16.3 0.0 1.9 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 ETS77339.1 - 0.0056 16.6 0.0 0.0096 15.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain ABC_tran PF00005.27 ETS77339.1 - 0.024 15.1 0.0 0.049 14.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter T4SS-DNA_transf PF02534.14 ETS77339.1 - 0.038 12.8 0.1 0.17 10.6 0.0 1.9 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer ATPase_2 PF01637.18 ETS77339.1 - 0.1 12.5 0.1 0.33 10.8 0.1 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Aminotran_1_2 PF00155.21 ETS77340.1 - 1.2e-34 120.1 0.0 1.3e-34 120.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.32 ETS77341.1 - 9.3e-15 54.8 10.3 0.0095 16.8 0.0 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS77341.1 - 3.9e-10 39.9 0.2 0.0014 18.9 0.2 5.3 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ETS77341.1 - 0.00084 19.3 0.4 0.45 10.4 0.0 3.7 4 1 2 6 6 6 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 ETS77341.1 - 0.00086 19.2 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 LisH PD40 PF07676.12 ETS77341.1 - 0.0026 17.7 0.4 3.7 7.6 0.0 3.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Yeast-kill-tox PF09207.11 ETS77341.1 - 0.0038 17.8 0.3 0.017 15.8 0.1 2.1 2 0 0 2 2 2 1 Yeast killer toxin DUF1751 PF08551.10 ETS77342.1 - 7.1e-26 90.7 4.6 7.1e-26 90.7 4.6 1.9 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) CBP_BcsO PF17037.5 ETS77342.1 - 0.32 11.1 2.9 0.61 10.2 2.9 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO Rhomboid PF01694.22 ETS77342.1 - 0.43 10.6 11.4 0.77 9.8 11.4 1.3 1 0 0 1 1 1 0 Rhomboid family TPR_1 PF00515.28 ETS77343.1 - 8.7e-50 164.6 29.4 5.9e-08 32.2 0.1 10.7 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 ETS77343.1 - 3.4e-45 148.5 22.1 3.9e-06 26.5 0.0 10.5 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 ETS77343.1 - 4.6e-40 132.5 18.8 1.3e-06 28.2 0.0 10.7 10 1 0 10 10 10 10 Tetratricopeptide repeat TPR_17 PF13431.6 ETS77343.1 - 3.4e-28 96.0 15.4 0.0021 18.3 0.1 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 ETS77343.1 - 6e-27 92.0 10.8 0.00041 20.9 0.0 9.3 3 2 6 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.6 ETS77343.1 - 1e-24 85.9 27.5 3.8e-06 26.5 0.2 9.5 5 2 4 9 9 9 6 TPR repeat TPR_19 PF14559.6 ETS77343.1 - 2.6e-24 85.5 17.1 8.6e-05 23.0 0.1 6.2 4 1 2 6 6 6 6 Tetratricopeptide repeat TPR_16 PF13432.6 ETS77343.1 - 2.6e-24 85.6 11.3 3.4e-06 27.6 0.4 6.6 3 3 4 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 ETS77343.1 - 3.8e-20 72.0 21.4 4.3e-05 23.7 0.8 7.5 3 2 5 8 8 8 7 Tetratricopeptide repeat TPR_6 PF13174.6 ETS77343.1 - 1.5e-19 69.3 14.2 0.0038 17.8 0.0 9.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 ETS77343.1 - 4.8e-15 54.4 15.9 0.01 15.8 0.1 9.3 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 ETS77343.1 - 8.1e-15 54.7 11.0 0.00092 19.3 0.2 6.4 3 2 3 7 7 7 5 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS77343.1 - 2.2e-13 50.2 9.2 1.4e-08 34.9 1.5 3.6 4 1 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 ETS77343.1 - 1.1e-10 41.2 6.9 0.0037 16.5 0.1 5.0 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_21 PF09976.9 ETS77343.1 - 1.4e-07 31.4 4.6 0.28 10.9 0.0 5.2 4 2 0 4 4 4 3 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 ETS77343.1 - 0.0009 19.5 3.5 1.9 8.9 0.0 3.9 3 2 1 4 4 3 2 Tetratricopeptide repeat DUF2225 PF09986.9 ETS77343.1 - 0.024 14.4 1.5 0.91 9.2 0.0 2.8 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Cohesin_load PF10345.9 ETS77343.1 - 0.46 8.9 2.9 7.9 4.8 0.1 2.7 2 1 1 3 3 3 0 Cohesin loading factor SNAP PF14938.6 ETS77343.1 - 0.71 9.2 12.8 17 4.8 0.4 4.5 1 1 2 3 3 3 0 Soluble NSF attachment protein, SNAP BTAD PF03704.17 ETS77343.1 - 2.4 8.6 15.3 11 6.5 0.1 3.8 4 0 0 4 4 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 ETS77343.1 - 2.7 8.0 22.9 11 6.1 0.0 7.6 9 0 0 9 9 8 0 Tetratricopeptide repeat Ribosomal_L3 PF00297.22 ETS77344.1 - 8.9e-175 581.0 14.8 1e-166 554.5 7.5 2.0 2 0 0 2 2 2 2 Ribosomal protein L3 NuiA PF07924.11 ETS77345.1 - 1.2e-05 25.7 0.0 0.0021 18.4 0.0 2.2 1 1 0 1 1 1 1 Nuclease A inhibitor-like protein Chorismate_bind PF00425.18 ETS77346.1 - 9.7e-91 303.9 0.0 3.9e-90 301.9 0.0 1.8 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 ETS77346.1 - 1.7e-26 93.1 0.0 5.8e-22 78.4 0.0 3.6 4 0 0 4 4 4 2 Anthranilate synthase component I, N terminal region Sigma70_r1_1 PF03979.14 ETS77346.1 - 0.15 12.2 0.4 3.9 7.6 0.1 2.4 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 Mycoplasma_p37 PF06646.11 ETS77346.1 - 0.23 10.6 0.2 0.45 9.7 0.0 1.5 2 0 0 2 2 2 0 High affinity transport system protein p37 GFA PF04828.14 ETS77347.1 - 0.00042 20.6 0.2 0.00042 20.6 0.2 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme A2L_zn_ribbon PF08792.10 ETS77347.1 - 0.052 13.3 0.1 0.052 13.3 0.1 2.6 3 0 0 3 3 3 0 A2L zinc ribbon domain Sec6 PF06046.13 ETS77348.1 - 7.9e-164 546.2 4.7 1e-163 545.8 4.7 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Syntaxin_2 PF14523.6 ETS77348.1 - 0.011 16.1 1.4 1.7 9.1 0.1 2.7 2 0 0 2 2 2 0 Syntaxin-like protein OmdA PF13376.6 ETS77348.1 - 0.071 13.1 0.9 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Vps53_N PF04100.12 ETS77348.1 - 0.29 10.1 9.4 0.014 14.4 1.0 3.0 3 2 1 4 4 4 0 Vps53-like, N-terminal LZ3wCH PF18517.1 ETS77348.1 - 2.4 8.3 6.5 6.8 6.9 0.4 4.1 4 0 0 4 4 4 0 Leucine zipper with capping helix domain MFS_1 PF07690.16 ETS77349.1 - 3.8e-08 32.6 29.8 3.8e-08 32.6 29.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 ETS77349.1 - 8.7e-07 28.8 2.7 8.7e-07 28.8 2.7 3.2 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 SesA PF17107.5 ETS77350.1 - 1.8e-16 60.4 0.0 2.7e-15 56.6 0.0 2.5 2 1 1 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT_sigma PF17106.5 ETS77350.1 - 1e-05 25.6 19.5 1.6e-05 24.9 19.5 1.3 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases DUF5066 PF16728.5 ETS77350.1 - 0.029 13.7 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5066) SesA PF17107.5 ETS77351.1 - 1.3e-41 141.6 0.0 1.6e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT_sigma PF17106.5 ETS77351.1 - 1.2e-06 28.5 17.4 2e-06 27.8 17.4 1.4 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases HET PF06985.11 ETS77352.1 - 1.8e-10 41.3 8.7 1e-08 35.7 0.5 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) DUF3417 PF11897.8 ETS77352.1 - 0.18 12.2 2.0 0.48 10.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) Wtap PF17098.5 ETS77352.1 - 0.34 10.8 3.5 0.21 11.5 1.6 1.6 2 0 0 2 2 2 0 WTAP/Mum2p family Glyco_hydro_18 PF00704.28 ETS77353.1 - 3.1e-69 234.1 5.7 4.9e-69 233.4 5.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ETS77353.1 - 6.5e-12 45.7 14.8 6.5e-12 45.7 14.8 4.2 5 0 0 5 5 5 2 Chitin recognition protein LysM PF01476.20 ETS77354.1 - 1.5e-09 37.8 0.4 0.0017 18.4 0.1 3.2 3 0 0 3 3 3 2 LysM domain WD40 PF00400.32 ETS77356.1 - 3.2e-16 59.4 1.6 1.1e-08 35.5 0.1 3.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS77356.1 - 1.2e-05 25.5 0.0 0.19 12.1 0.0 3.5 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ETS77356.1 - 3.1e-05 22.8 1.1 0.021 13.5 0.0 2.1 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ETS77356.1 - 0.044 12.7 0.2 1.1 8.2 0.1 2.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HET PF06985.11 ETS77357.1 - 1.2e-26 93.8 0.6 1.8e-26 93.3 0.6 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 ETS77358.1 - 1.4e-11 44.7 0.0 4.5e-05 24.1 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat PNP_UDP_1 PF01048.20 ETS77358.1 - 6.9e-09 35.3 0.2 2.9e-08 33.3 0.2 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.6 ETS77358.1 - 3.4e-08 34.1 0.1 1.5e-07 32.0 0.1 2.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 ETS77358.1 - 2.3e-07 30.9 0.0 5.1e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 ETS77358.1 - 9.8e-06 25.8 0.0 0.013 15.7 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain AAA PF00004.29 ETS77358.1 - 4.1e-05 24.0 0.6 0.00052 20.4 0.1 2.9 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ETS77358.1 - 0.00078 19.2 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ETS77358.1 - 0.00093 19.5 0.0 0.0028 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ETS77358.1 - 0.017 15.5 0.0 0.047 14.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Roc PF08477.13 ETS77358.1 - 0.046 13.9 0.0 4.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PhoH PF02562.16 ETS77358.1 - 0.056 12.9 0.1 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.22 ETS77358.1 - 0.06 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 ETS77358.1 - 0.08 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Nup160 PF11715.8 ETS77358.1 - 0.1 11.2 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Parvo_NS1 PF01057.17 ETS77358.1 - 0.13 11.3 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_5 PF07728.14 ETS77358.1 - 0.15 12.1 0.0 0.46 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 ETS77358.1 - 0.15 12.6 0.0 0.46 11.0 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Cytidylate_kin PF02224.18 ETS77358.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_29 PF13555.6 ETS77358.1 - 0.16 11.7 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ge1_WD40 PF16529.5 ETS77358.1 - 0.19 10.7 0.0 0.53 9.2 0.0 1.7 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RsgA_GTPase PF03193.16 ETS77358.1 - 0.19 11.6 0.0 0.66 9.9 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase HET PF06985.11 ETS77359.1 - 1.1e-24 87.5 0.0 1.9e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SICA_beta PF12878.7 ETS77359.1 - 0.096 12.9 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 SICA extracellular beta domain p450 PF00067.22 ETS77360.1 - 4.9e-41 141.0 0.0 6.1e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.7 ETS77361.1 - 2.4e-06 28.3 0.2 2.9e-06 28.0 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family ABC_tran PF00005.27 ETS77362.1 - 3.2e-42 144.3 0.0 1.1e-26 93.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS77362.1 - 6e-33 114.7 35.0 9.1e-26 91.1 13.9 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ETS77362.1 - 2.4e-12 46.8 0.1 7.7e-05 22.2 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETS77362.1 - 2e-08 34.4 0.1 0.01 15.7 0.0 3.5 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ETS77362.1 - 5.1e-08 33.7 0.1 0.0015 19.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ETS77362.1 - 1.4e-07 31.2 1.1 0.0074 16.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 ETS77362.1 - 3.8e-06 27.1 0.3 0.015 15.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 ETS77362.1 - 1.9e-05 24.9 0.7 0.0034 17.7 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS77362.1 - 4.2e-05 24.0 0.0 0.036 14.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 ETS77362.1 - 0.00014 21.9 0.0 0.66 10.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 ETS77362.1 - 0.00031 20.4 0.8 0.069 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ETS77362.1 - 0.0007 19.5 0.0 0.26 11.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 ETS77362.1 - 0.0026 17.5 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 ETS77362.1 - 0.0027 17.3 2.3 0.084 12.5 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 ETS77362.1 - 0.0044 16.1 0.1 0.13 11.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 ETS77362.1 - 0.0064 15.9 0.1 0.12 11.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.23 ETS77362.1 - 0.0076 16.3 0.0 0.49 10.4 0.0 2.3 2 0 0 2 2 2 1 Dynamin family AAA_18 PF13238.6 ETS77362.1 - 0.012 16.2 0.3 0.11 13.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ETS77362.1 - 0.015 15.0 0.0 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 ETS77362.1 - 0.016 14.4 0.0 7.4 5.7 0.0 2.8 2 1 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 ETS77362.1 - 0.027 14.2 2.8 0.6 9.8 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein SbcCD_C PF13558.6 ETS77362.1 - 0.029 14.6 0.0 18 5.6 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MobB PF03205.14 ETS77362.1 - 0.07 13.0 0.4 0.23 11.4 0.1 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.10 ETS77362.1 - 0.076 12.4 0.1 0.73 9.2 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PRK PF00485.18 ETS77362.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Pox_A32 PF04665.12 ETS77362.1 - 0.099 12.1 1.8 0.32 10.4 0.0 2.4 3 0 0 3 3 3 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 ETS77362.1 - 0.15 11.8 0.6 4 7.1 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 ETS77362.1 - 0.26 11.2 1.1 0.77 9.6 0.0 2.3 3 0 0 3 3 3 0 NTPase AAA_28 PF13521.6 ETS77362.1 - 0.44 10.8 1.3 1.2 9.4 0.2 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ETS77362.1 - 0.45 10.4 3.6 0.42 10.5 0.1 2.7 3 0 0 3 3 3 0 NACHT domain ABC_ATPase PF09818.9 ETS77362.1 - 0.97 8.2 4.1 1.6 7.5 0.1 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class MFS_1 PF07690.16 ETS77363.1 - 2.8e-22 79.1 38.4 5.2e-18 65.1 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 ETS77363.1 - 5.1e-06 25.2 7.2 5.1e-06 25.2 7.2 1.9 1 1 1 2 2 2 1 Transmembrane secretion effector HET PF06985.11 ETS77364.1 - 2e-13 50.9 2.9 1e-09 38.9 0.2 3.1 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Na_Ca_ex PF01699.24 ETS77365.1 - 6.4e-07 29.4 9.3 0.002 18.1 2.1 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein ACT PF01842.25 ETS77367.1 - 4.1e-15 55.3 0.1 7.2e-15 54.5 0.1 1.4 1 0 0 1 1 1 1 ACT domain ALS_ss_C PF10369.9 ETS77367.1 - 5.4e-14 52.2 0.0 4.4e-13 49.2 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 ETS77367.1 - 2.6e-08 33.6 0.0 4.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 ACT domain OTCace_N PF02729.21 ETS77368.1 - 1.7e-44 151.5 0.1 2.4e-44 150.9 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 ETS77368.1 - 1.3e-43 148.8 0.0 2e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain KH_1 PF00013.29 ETS77369.1 - 8.6e-09 35.1 0.0 2e-06 27.5 0.0 2.7 2 0 0 2 2 2 2 KH domain DEAD PF00270.29 ETS77370.1 - 2.6e-31 108.8 0.3 7.3e-15 55.2 0.0 2.8 2 1 1 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS77370.1 - 1.2e-20 73.9 0.1 4.2e-20 72.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS77370.1 - 7.2e-06 26.1 0.2 6e-05 23.1 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AF-4 PF05110.13 ETS77370.1 - 0.0016 16.7 10.1 0.0016 16.7 10.1 2.5 2 0 0 2 2 2 1 AF-4 proto-oncoprotein DUF3246 PF11596.8 ETS77370.1 - 0.0031 17.0 3.0 0.0031 17.0 3.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3246) UvrD-helicase PF00580.21 ETS77370.1 - 0.02 14.4 1.8 0.16 11.4 0.0 2.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain MFMR_assoc PF16596.5 ETS77370.1 - 0.23 11.9 13.0 0.24 11.9 5.1 2.5 2 0 0 2 2 2 0 Disordered region downstream of MFMR SR-25 PF10500.9 ETS77370.1 - 1.8 8.1 31.6 0.43 10.2 10.9 2.9 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein PIGA PF08288.12 ETS77371.1 - 6.8e-46 154.8 3.8 1e-45 154.2 0.7 2.5 3 0 0 3 3 3 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 ETS77371.1 - 2.1e-28 99.4 0.2 3.6e-28 98.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 ETS77371.1 - 1.9e-26 92.6 0.0 3.7e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ETS77371.1 - 3.1e-22 79.4 0.1 6.2e-22 78.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ETS77371.1 - 3.1e-12 47.2 0.0 5.6e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 ETS77371.1 - 3.3e-06 27.2 0.1 5.8e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 ETS77371.1 - 0.0029 18.0 0.0 0.013 15.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 POTRA_2 PF08479.11 ETS77373.1 - 0.17 11.7 1.6 52 3.8 0.0 3.7 3 2 1 4 4 4 0 POTRA domain, ShlB-type DNA_pol3_a_NI PF14480.6 ETS77373.1 - 0.26 11.3 2.6 24 5.0 0.0 3.8 5 0 0 5 5 5 0 DNA polymerase III polC-type N-terminus I AT_hook PF02178.19 ETS77373.1 - 8.9 6.6 13.6 0.69 10.0 6.3 2.7 2 0 0 2 2 2 0 AT hook motif Nop14 PF04147.12 ETS77374.1 - 1.2 7.3 18.9 1.5 6.9 18.9 1.0 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 ETS77374.1 - 6.9 6.7 24.2 13 5.8 24.2 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Ribonuclease_3 PF00636.26 ETS77375.1 - 2.3e-34 118.2 0.0 5.6e-19 68.7 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 ETS77375.1 - 1.6e-22 79.5 1.1 3.6e-22 78.3 0.4 2.1 2 0 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 ETS77375.1 - 4.4e-22 78.6 0.0 1.1e-09 38.5 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like DEAD PF00270.29 ETS77375.1 - 1.9e-19 70.1 0.0 3.8e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS77375.1 - 3.2e-17 62.9 0.4 2.8e-16 59.8 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS77375.1 - 7.9e-16 58.5 0.0 1.4e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.26 ETS77375.1 - 3.1e-07 31.0 0.2 0.0042 17.8 0.1 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif Apocytochr_F_C PF01333.19 ETS77375.1 - 0.0075 16.3 0.3 0.018 15.0 0.3 1.6 1 0 0 1 1 1 1 Apocytochrome F, C-terminal RCC1 PF00415.18 ETS77376.1 - 6.9e-19 68.2 1.9 1.9e-07 31.6 0.0 4.8 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ETS77376.1 - 3.6e-17 61.7 6.5 7e-06 25.7 0.6 4.5 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Proteasome PF00227.26 ETS77377.1 - 2.1e-57 193.7 0.0 1.2e-32 113.0 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 ETS77377.1 - 1.3e-10 40.8 0.3 3.2e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature GRDB PF07355.12 ETS77377.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) RINGv PF12906.7 ETS77378.1 - 4e-09 36.5 8.4 4e-09 36.5 8.4 1.8 2 0 0 2 2 2 1 RING-variant domain CDC24_OB3 PF17244.2 ETS77378.1 - 0.17 11.6 0.2 0.25 11.0 0.2 1.2 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 PHD PF00628.29 ETS77378.1 - 0.41 10.6 9.3 0.093 12.6 5.5 1.8 2 0 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 ETS77378.1 - 1.2 9.2 10.1 21 5.3 0.0 2.4 1 1 1 2 2 2 0 PHD-finger VIT1 PF01988.19 ETS77378.1 - 1.3 8.8 3.2 10 5.9 0.1 2.3 2 0 0 2 2 2 0 VIT family Glyco_transf_34 PF05637.12 ETS77379.1 - 7.1e-72 242.0 0.0 8.6e-72 241.7 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 ETS77379.1 - 0.07 12.7 0.0 1 8.9 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF273 Pyridoxal_deC PF00282.19 ETS77380.1 - 5.9e-17 61.4 0.0 8.7e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 ETS77380.1 - 0.00013 21.0 0.0 0.00024 20.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V BCDHK_Adom3 PF10436.9 ETS77381.1 - 3.9e-76 254.4 0.0 5.7e-76 253.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ETS77381.1 - 5.3e-13 49.4 0.0 1.2e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ETS77381.1 - 0.088 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Packaging_FI PF14000.6 ETS77382.1 - 0.07 13.6 0.1 0.07 13.6 0.1 2.4 2 1 0 2 2 2 0 DNA packaging protein FI FUSC PF04632.12 ETS77382.1 - 1.5 7.3 11.9 1.8 7.0 11.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family XhlA PF10779.9 ETS77382.1 - 2.1 8.6 7.8 3.2 8.0 0.8 3.0 2 1 1 3 3 3 0 Haemolysin XhlA MerR-DNA-bind PF09278.11 ETS77382.1 - 2.1 8.9 11.7 8.6 7.0 7.9 2.8 2 0 0 2 2 2 0 MerR, DNA binding Sugar_tr PF00083.24 ETS77383.1 - 4.3e-89 299.4 23.7 5.3e-89 299.2 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS77383.1 - 2.8e-22 79.1 54.8 3e-21 75.7 22.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily VIT1 PF01988.19 ETS77383.1 - 9.3 6.1 6.7 3.4 7.5 0.3 3.0 2 1 1 3 3 3 0 VIT family Stc1 PF12898.7 ETS77385.1 - 1.6e-21 76.6 0.5 3.1e-21 75.7 0.5 1.5 1 0 0 1 1 1 1 Stc1 domain SDA1 PF05285.12 ETS77385.1 - 0.5 9.7 3.8 0.8 9.1 3.8 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 ETS77385.1 - 0.66 9.2 7.9 1 8.6 7.9 1.2 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 ETS77385.1 - 2.1 8.0 8.7 4.7 6.9 8.7 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 ETS77385.1 - 5.3 5.1 5.5 7 4.7 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 ETS77385.1 - 9.7 4.6 5.7 13 4.1 5.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pkinase PF00069.25 ETS77386.1 - 8e-55 186.0 0.0 1.2e-54 185.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS77386.1 - 3.8e-30 105.0 0.0 1.4e-28 99.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ETS77386.1 - 0.014 14.4 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 ETS77386.1 - 0.035 13.1 0.0 0.05 12.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 ETS77386.1 - 0.16 11.3 0.3 0.38 10.1 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSP70 PF00012.20 ETS77387.1 - 4.7e-09 35.0 0.1 3e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein FtsA PF14450.6 ETS77387.1 - 0.0013 19.1 0.0 0.02 15.3 0.0 2.4 2 0 0 2 2 2 1 Cell division protein FtsA SARAF PF06682.12 ETS77387.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SNF2_N PF00176.23 ETS77388.1 - 7e-66 222.3 0.0 9.7e-66 221.8 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS77388.1 - 3e-12 46.9 0.0 1e-11 45.1 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ETS77388.1 - 7e-08 32.4 0.0 3e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 ETS77388.1 - 5.4e-05 23.1 7.1 0.00012 22.0 7.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ETS77388.1 - 0.00098 19.0 7.8 0.0024 17.7 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS77388.1 - 0.0034 17.2 7.5 0.0088 15.9 7.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ETS77388.1 - 0.0063 16.3 5.4 0.016 15.1 5.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 ETS77388.1 - 0.011 15.8 1.6 0.026 14.6 1.6 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger Prok-RING_4 PF14447.6 ETS77388.1 - 0.018 14.9 6.8 0.039 13.8 6.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 AAA_34 PF13872.6 ETS77388.1 - 0.034 13.0 0.0 0.1 11.5 0.0 1.7 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 zf-RING_2 PF13639.6 ETS77388.1 - 0.1 13.0 6.8 0.24 11.8 6.8 1.7 1 0 0 1 1 1 0 Ring finger domain Suv3_N PF18114.1 ETS77388.1 - 0.13 12.4 0.0 7.9 6.6 0.0 2.8 3 0 0 3 3 3 0 Suv3 helical N-terminal domain zf-C3HC4_5 PF17121.5 ETS77388.1 - 1.5 8.8 5.0 7 6.6 4.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) NACHT PF05729.12 ETS77389.1 - 3.1e-10 40.2 0.1 1.6e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 NACHT domain zf-C2H2 PF00096.26 ETS77389.1 - 3.5e-07 30.3 29.0 0.001 19.4 0.4 6.0 6 0 0 6 6 5 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 ETS77389.1 - 0.00018 21.7 1.2 0.00063 20.0 1.2 2.0 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 ETS77389.1 - 0.0011 19.6 6.7 0.015 16.1 1.2 5.7 6 0 0 6 6 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ETS77389.1 - 0.0018 18.6 21.9 0.41 11.2 0.0 6.8 7 0 0 7 7 7 2 Zinc-finger double domain zf-met PF12874.7 ETS77389.1 - 0.0018 18.6 5.1 0.96 9.9 0.1 3.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type AAA_22 PF13401.6 ETS77389.1 - 0.0045 17.3 0.0 0.016 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS77389.1 - 0.011 16.2 0.4 0.051 14.0 0.0 2.4 3 0 0 3 3 2 0 AAA ATPase domain zf-XS PF03470.14 ETS77389.1 - 0.023 15.0 0.8 0.061 13.6 0.8 1.8 1 0 0 1 1 1 0 XS zinc finger domain AAA PF00004.29 ETS77389.1 - 0.024 15.1 0.0 0.062 13.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-C2H2_jaz PF12171.8 ETS77389.1 - 0.024 14.9 15.2 0.31 11.4 0.1 4.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ETS77389.1 - 0.042 13.9 8.4 1.4 9.0 1.0 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 ETS77389.1 - 0.2 11.6 2.9 0.28 11.0 0.2 2.7 3 1 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Trp_halogenase PF04820.14 ETS77390.1 - 0.059 12.2 0.4 0.094 11.5 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Arteri_env PF01606.16 ETS77390.1 - 0.089 12.7 1.2 0.1 12.4 0.4 1.5 1 1 0 1 1 1 0 Arterivirus envelope protein HET PF06985.11 ETS77391.1 - 5.7e-11 43.0 2.1 1.3e-10 41.8 2.1 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Spike_NTD PF16451.5 ETS77391.1 - 0.1 11.9 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 Spike glycoprotein N-terminal domain DUF1772 PF08592.11 ETS77392.1 - 2.5e-13 50.5 1.5 1.1e-05 25.7 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF1772) DUF4448 PF14610.6 ETS77393.1 - 0.001 18.9 0.0 0.0028 17.5 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.10 ETS77393.1 - 0.013 14.9 0.1 0.042 13.3 0.1 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1314 PF07013.11 ETS77393.1 - 0.11 12.4 0.6 0.18 11.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) Podoplanin PF05808.11 ETS77393.1 - 0.18 11.9 4.8 0.054 13.6 1.2 1.9 2 0 0 2 2 2 0 Podoplanin TMEM154 PF15102.6 ETS77393.1 - 0.21 11.5 12.4 3.3 7.6 12.4 2.3 1 1 0 1 1 1 0 TMEM154 protein family LRRC37AB_C PF14914.6 ETS77393.1 - 0.22 11.4 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain MGC-24 PF05283.11 ETS77393.1 - 1.5 9.2 11.4 0.25 11.8 7.0 1.9 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FAD_binding_4 PF01565.23 ETS77396.1 - 1.5e-21 76.6 2.6 3.7e-21 75.3 2.6 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS77396.1 - 2.2e-11 43.7 0.2 4.9e-11 42.6 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 ETS77396.1 - 0.009 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding HET PF06985.11 ETS77398.1 - 4e-36 124.6 0.5 6.1e-36 124.0 0.5 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BNR PF02012.20 ETS77399.1 - 5.6e-09 34.7 18.3 0.75 10.0 0.7 6.9 6 0 0 6 6 6 5 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 ETS77399.1 - 7.6e-06 25.0 0.0 0.37 9.5 0.0 3.9 4 0 0 4 4 4 3 Sortilin, neurotensin receptor 3, BNR_2 PF13088.6 ETS77399.1 - 8.1e-06 25.3 0.0 0.17 11.1 0.0 3.3 1 1 1 2 2 2 2 BNR repeat-like domain CHB_HEX_C PF03174.13 ETS77399.1 - 0.0058 16.6 0.0 25 4.9 0.0 3.5 2 1 1 3 3 3 2 Chitobiase/beta-hexosaminidase C-terminal domain LVIVD PF08309.11 ETS77399.1 - 0.068 12.5 0.1 0.16 11.3 0.1 1.6 1 0 0 1 1 1 0 LVIVD repeat RTA1 PF04479.13 ETS77400.1 - 2.3e-58 197.2 9.9 2.3e-58 197.2 9.9 1.7 1 1 1 2 2 2 1 RTA1 like protein Fungal_trans_2 PF11951.8 ETS77401.1 - 0.0037 16.1 2.2 0.014 14.3 0.1 2.2 2 1 0 2 2 2 2 Fungal specific transcription factor domain CFEM PF05730.11 ETS77403.1 - 2.3e-09 37.2 10.1 3.9e-09 36.5 10.1 1.4 1 0 0 1 1 1 1 CFEM domain Fungal_trans PF04082.18 ETS77404.1 - 2.7e-27 95.5 0.0 4.8e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS77404.1 - 1e-06 28.8 9.4 2.1e-06 27.8 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLAC9 PF15205.6 ETS77404.1 - 0.18 12.2 0.2 0.63 10.5 0.0 1.9 2 0 0 2 2 2 0 Placenta-specific protein 9 MFS_1 PF07690.16 ETS77405.1 - 3.6e-34 118.2 24.0 5.3e-34 117.7 24.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS77405.1 - 0.0012 17.8 5.5 0.0018 17.2 5.5 1.3 1 1 0 1 1 1 1 MFS_1 like family Myb_DNA-binding PF00249.31 ETS77405.1 - 0.082 13.1 0.4 37 4.6 0.0 3.3 3 0 0 3 3 3 0 Myb-like DNA-binding domain CD47 PF04549.14 ETS77405.1 - 4.3 7.5 9.6 0.069 13.3 0.9 2.2 2 1 0 2 2 2 0 CD47 transmembrane region HAD_2 PF13419.6 ETS77406.1 - 3e-12 47.0 0.0 4e-11 43.3 0.0 1.9 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETS77406.1 - 2.7e-05 24.5 0.0 0.0025 18.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase STAT2_C PF12188.8 ETS77406.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Signal transducer and activator of transcription 2 C terminal DAO PF01266.24 ETS77407.1 - 1.8e-42 146.2 0.2 2.1e-42 146.0 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS77407.1 - 0.00083 19.4 1.9 0.0066 16.4 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ETS77407.1 - 0.0012 19.1 0.1 0.0026 17.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS77407.1 - 0.0017 17.5 0.5 1.4 8.0 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 ETS77407.1 - 0.0018 17.6 0.0 0.044 13.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS77407.1 - 0.023 13.9 0.2 0.24 10.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS77407.1 - 0.15 11.2 0.0 0.34 10.0 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Raffinose_syn PF05691.12 ETS77408.1 - 2.9e-27 94.8 0.7 1.2e-24 86.2 0.1 3.2 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 MFS_1 PF07690.16 ETS77409.1 - 1.5e-41 142.5 28.3 1.5e-41 142.5 28.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS77409.1 - 4.2e-13 49.0 1.6 4.2e-13 49.0 1.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 ETS77409.1 - 6.8e-05 21.4 4.4 9.7e-05 20.9 4.4 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.20 ETS77409.1 - 0.054 11.8 0.1 0.14 10.4 0.1 1.6 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Aldo_ket_red PF00248.21 ETS77410.1 - 9.6e-52 176.0 0.0 1.1e-51 175.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.8 ETS77411.1 - 0.0093 14.8 0.6 0.033 13.0 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Protoglobin PF11563.8 ETS77411.1 - 0.019 14.9 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 Protoglobin MetOD2 PF18548.1 ETS77411.1 - 0.033 14.3 0.0 0.077 13.1 0.0 1.6 1 0 0 1 1 1 0 Metanogen output domain 2 RTA1 PF04479.13 ETS77412.1 - 7.1e-71 238.1 0.7 1e-70 237.5 0.7 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4013 PF13197.6 ETS77412.1 - 0.036 13.9 0.0 0.036 13.9 0.0 2.4 2 2 1 3 3 3 0 Protein of unknown function (DUF4013) Oleosin PF01277.17 ETS77412.1 - 0.23 11.2 2.3 7 6.5 0.1 3.0 3 0 0 3 3 3 0 Oleosin Inositol_P PF00459.25 ETS77412.1 - 0.32 10.5 0.6 0.52 9.8 0.2 1.4 2 0 0 2 2 2 0 Inositol monophosphatase family Oxidored_q2 PF00420.24 ETS77412.1 - 0.61 9.7 0.0 0.61 9.7 0.0 2.7 2 2 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF2236 PF09995.9 ETS77413.1 - 3e-31 109.4 0.0 4.5e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) HGTP_anticodon PF03129.20 ETS77413.1 - 0.05 13.8 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 Anticodon binding domain F-box PF00646.33 ETS77415.1 - 0.0069 16.2 0.2 0.028 14.3 0.0 2.1 2 0 0 2 2 2 1 F-box domain p450 PF00067.22 ETS77416.1 - 5.9e-69 233.0 0.0 7.1e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 ETS77417.1 - 2.6e-31 108.9 77.9 1.1e-23 83.7 43.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS77417.1 - 8e-06 25.0 11.6 8e-06 25.0 11.6 4.0 2 2 2 4 4 4 2 Sugar (and other) transporter Abhydrolase_1 PF00561.20 ETS77418.1 - 3.7e-08 33.3 0.1 6.8e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS77418.1 - 4.5e-08 34.0 0.2 1.1e-07 32.8 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS77418.1 - 9.9e-05 21.7 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 ETS77418.1 - 0.077 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) adh_short PF00106.25 ETS77419.1 - 2.8e-22 79.1 2.5 1.2e-20 73.8 2.5 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS77419.1 - 2.4e-11 43.6 1.5 1.7e-10 40.9 1.5 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS77419.1 - 6.6e-08 32.7 0.3 1.1e-07 31.9 0.3 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ETS77419.1 - 0.00011 22.5 0.1 0.00022 21.5 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ETS77419.1 - 0.0024 17.9 0.1 0.0079 16.3 0.0 1.8 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 ETS77419.1 - 0.027 13.9 0.1 0.045 13.2 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ETS77419.1 - 0.065 12.4 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Abhydrolase_1 PF00561.20 ETS77420.1 - 1.7e-12 47.6 0.0 2e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS77420.1 - 6.7e-10 38.6 0.0 9.5e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS77420.1 - 1.7e-06 28.8 0.0 1.9e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF642 PF04862.12 ETS77421.1 - 0.023 14.5 0.2 0.023 14.5 0.2 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF642) HET PF06985.11 ETS77422.1 - 3.4e-30 105.3 0.9 1e-25 90.8 0.0 3.1 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.19 ETS77423.1 - 1.1e-22 80.8 0.0 1.4e-21 77.1 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ETS77423.1 - 3.4e-07 29.8 0.1 4.1e-06 26.3 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS77423.1 - 8.6e-06 25.2 0.1 0.0022 17.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS77423.1 - 3.4e-05 23.1 0.0 6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ETS77423.1 - 4.4e-05 23.6 0.0 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ETS77423.1 - 0.0001 22.8 0.6 0.0011 19.5 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS77423.1 - 0.00083 19.0 0.2 0.02 14.5 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ETS77423.1 - 0.0015 17.4 1.9 0.066 12.0 0.2 2.6 3 0 0 3 3 3 1 Tryptophan halogenase AlaDh_PNT_C PF01262.21 ETS77423.1 - 0.014 14.7 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ETS77423.1 - 0.017 14.4 0.1 0.03 13.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 ETS77423.1 - 0.028 13.5 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 ETS77423.1 - 0.055 12.7 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase SE PF08491.10 ETS77423.1 - 0.082 12.0 0.0 0.22 10.5 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase HI0933_like PF03486.14 ETS77423.1 - 0.097 11.4 0.8 0.88 8.2 0.2 2.4 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.6 ETS77423.1 - 0.13 12.2 0.3 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 ETS77423.1 - 0.16 12.4 0.0 0.63 10.5 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Lactonase PF10282.9 ETS77424.1 - 2.7e-25 89.3 0.2 5.6e-24 85.0 0.1 2.4 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Dioxygenase_C PF00775.21 ETS77425.1 - 5.6e-08 32.4 0.0 1e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 Dioxygenase Lactonase PF10282.9 ETS77426.1 - 7.8e-24 84.6 0.5 1e-23 84.2 0.5 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 ETS77426.1 - 0.0078 15.8 0.2 0.33 10.5 0.0 2.4 1 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Prok-E2_C PF14459.6 ETS77426.1 - 0.034 14.3 0.2 0.072 13.3 0.2 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family C SBP56 PF05694.11 ETS77426.1 - 0.12 11.2 0.0 7.7 5.2 0.0 2.1 2 0 0 2 2 2 0 56kDa selenium binding protein (SBP56) Tyrosinase PF00264.20 ETS77427.1 - 1.4e-28 100.7 9.8 2.8e-28 99.7 9.8 1.4 1 1 0 1 1 1 1 Common central domain of tyrosinase Dioxygenase_C PF00775.21 ETS77428.1 - 1.3e-10 41.0 0.1 1.7e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 Dioxygenase ATP-synt_F PF01990.17 ETS77429.1 - 0.025 14.9 0.0 17 5.8 0.0 3.0 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit SAM_LFY PF01698.16 ETS77429.1 - 0.18 11.7 0.7 0.84 9.6 0.0 2.5 2 0 0 2 2 2 0 Floricaula / Leafy protein SAM domain COesterase PF00135.28 ETS77431.1 - 3.2e-91 306.8 0.0 6.1e-91 305.8 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS77431.1 - 8.1e-10 38.9 0.1 4.2e-09 36.6 0.1 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS77431.1 - 6.3e-06 25.8 0.0 1.6e-05 24.5 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family p450 PF00067.22 ETS77432.1 - 5.1e-71 239.8 0.0 6.6e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 ETS77433.1 - 1.9e-05 24.7 8.8 4.3e-05 23.6 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 ETS77434.1 - 9.2e-21 73.8 0.0 6.1e-15 54.6 0.1 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ETS77434.1 - 1e-20 74.2 0.0 2.1e-20 73.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS77434.1 - 3.6e-12 46.1 0.0 2.6e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS77434.1 - 3.1e-10 39.7 0.0 1.2e-07 31.3 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ETS77434.1 - 4e-06 27.0 0.0 0.0052 17.0 0.0 2.9 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ETS77434.1 - 1.1e-05 25.9 0.1 0.48 11.0 0.0 4.1 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 ETS77434.1 - 4.6e-05 22.9 0.0 0.021 14.2 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 ETS77434.1 - 0.00045 20.2 0.1 0.56 10.2 0.2 3.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 ETS77434.1 - 0.00059 19.3 0.0 2 7.7 0.0 3.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ETS77434.1 - 0.0011 18.3 0.0 1.5 7.9 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain FAD_binding_2 PF00890.24 ETS77434.1 - 0.0024 17.0 0.3 0.11 11.6 0.1 2.7 3 1 1 4 4 4 1 FAD binding domain HI0933_like PF03486.14 ETS77434.1 - 0.0033 16.2 0.0 0.2 10.3 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 ETS77434.1 - 0.0036 16.4 0.1 0.036 13.1 0.2 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 ETS77434.1 - 0.0046 16.6 1.0 0.57 9.7 0.1 3.3 2 2 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 ETS77434.1 - 0.014 14.7 0.0 5.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 ETS77434.1 - 0.16 12.2 0.0 0.45 10.8 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.22 ETS77434.1 - 0.2 10.7 0.0 2 7.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Aldo_ket_red PF00248.21 ETS77435.1 - 3.8e-51 174.0 0.1 4.3e-49 167.3 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Sof1 PF04158.14 ETS77435.1 - 0.12 12.6 0.1 0.44 10.8 0.0 1.9 2 0 0 2 2 2 0 Sof1-like domain GFO_IDH_MocA PF01408.22 ETS77436.1 - 2.7e-13 50.8 0.0 4.1e-12 47.0 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ETS77436.1 - 3.1e-06 27.2 0.0 5.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sugar_tr PF00083.24 ETS77437.1 - 1.3e-109 367.1 21.1 1.5e-109 366.9 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS77437.1 - 3.8e-20 72.1 44.8 7.8e-15 54.6 20.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS77437.1 - 2.3e-08 33.0 10.4 5.7e-06 25.0 3.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Ank_2 PF12796.7 ETS77438.1 - 1.6e-49 166.4 16.7 5.3e-10 39.7 0.1 7.6 3 2 2 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS77438.1 - 5.7e-34 116.1 12.6 1.9e-05 25.1 0.1 11.2 5 3 6 12 12 12 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS77438.1 - 2.4e-30 104.2 17.4 6.2e-09 36.0 0.1 9.9 5 3 5 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 ETS77438.1 - 1.5e-26 91.6 24.9 0.00051 20.4 0.1 12.1 13 0 0 13 13 13 7 Ankyrin repeat Ank_3 PF13606.6 ETS77438.1 - 8.9e-26 87.1 16.0 0.0035 17.7 0.0 13.7 14 0 0 14 14 13 5 Ankyrin repeat DUF676 PF05057.14 ETS77438.1 - 4.6e-05 23.0 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Cutinase PF01083.22 ETS77438.1 - 0.0004 20.4 0.0 0.00081 19.4 0.0 1.4 1 0 0 1 1 1 1 Cutinase PGAP1 PF07819.13 ETS77438.1 - 0.00049 19.9 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 ETS77438.1 - 0.0022 17.3 0.0 0.0044 16.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 ETS77438.1 - 0.0055 15.9 0.3 0.023 13.9 0.0 1.9 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 ETS77438.1 - 0.0081 16.8 0.0 0.0081 16.8 0.0 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family DUF726 PF05277.12 ETS77438.1 - 0.086 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DUF900 PF05990.12 ETS77438.1 - 0.088 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) ABC_export PF16962.5 ETS77439.1 - 0.0041 15.6 1.8 0.0055 15.2 1.8 1.1 1 0 0 1 1 1 1 Putative ABC exporter DUF4013 PF13197.6 ETS77439.1 - 0.0043 16.9 2.1 0.0067 16.3 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) DUF3309 PF11752.8 ETS77439.1 - 0.083 12.9 0.7 0.083 12.9 0.7 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3309) LRR19-TM PF15176.6 ETS77439.1 - 0.19 11.7 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain CcmD PF04995.14 ETS77439.1 - 0.22 11.7 3.7 4.3 7.5 2.1 2.7 1 1 1 2 2 2 0 Heme exporter protein D (CcmD) DUF2976 PF11190.8 ETS77439.1 - 0.31 10.9 4.1 0.53 10.1 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) FtsX PF02687.21 ETS77439.1 - 0.33 11.4 4.1 0.57 10.7 4.1 1.3 1 0 0 1 1 1 0 FtsX-like permease family DAO PF01266.24 ETS77440.1 - 3.4e-32 112.4 0.0 4.4e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS77440.1 - 6.4e-08 32.7 0.3 2.2e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS77440.1 - 0.00014 21.2 0.0 0.0017 17.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS77440.1 - 0.00027 20.1 0.0 0.024 13.7 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ETS77440.1 - 0.00028 20.2 0.0 0.00053 19.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 ETS77440.1 - 0.00036 19.8 0.0 0.00065 18.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 ETS77440.1 - 0.0017 18.6 0.0 0.0031 17.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 ETS77440.1 - 0.0022 18.1 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 ETS77440.1 - 0.003 16.5 0.3 0.018 13.9 0.3 1.9 1 1 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 ETS77440.1 - 0.0074 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 ETS77440.1 - 0.011 15.1 0.1 0.032 13.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 ETS77440.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 ThiF family Glu_dehyd_C PF16912.5 ETS77440.1 - 0.086 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus KR PF08659.10 ETS77440.1 - 0.089 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 KR domain Pyr_redox PF00070.27 ETS77440.1 - 0.1 13.2 0.1 0.32 11.6 0.0 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.32 ETS77442.1 - 3.6e-89 290.3 44.1 9.9e-10 38.9 1.0 13.6 13 0 0 13 13 13 11 WD domain, G-beta repeat Nup160 PF11715.8 ETS77442.1 - 2e-22 79.5 37.1 0.023 13.3 0.1 12.0 4 3 8 12 12 12 11 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 ETS77442.1 - 1.2e-11 44.7 17.0 0.042 14.1 0.1 8.8 3 2 9 12 12 11 4 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 ETS77442.1 - 3.4e-08 33.6 0.0 8e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS77442.1 - 4.3e-06 27.2 2.2 9.9e-06 26.0 0.1 2.6 3 0 0 3 3 2 1 AAA ATPase domain Nucleoporin_N PF08801.11 ETS77442.1 - 0.00013 20.9 21.2 0.018 13.8 2.2 5.6 1 1 4 5 5 5 3 Nup133 N terminal like AAA_22 PF13401.6 ETS77442.1 - 0.00013 22.2 0.2 0.19 12.0 0.0 3.7 4 0 0 4 4 4 1 AAA domain Me-amine-dh_H PF06433.11 ETS77442.1 - 0.0016 17.4 0.3 0.0038 16.1 0.1 1.7 2 0 0 2 2 2 1 Methylamine dehydrogenase heavy chain (MADH) ATPase_2 PF01637.18 ETS77442.1 - 0.0029 17.6 0.0 0.024 14.6 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Ge1_WD40 PF16529.5 ETS77442.1 - 0.0071 15.3 26.2 1.1 8.2 0.7 7.1 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein FG-GAP_2 PF14312.6 ETS77442.1 - 0.014 15.6 4.7 21 5.4 0.1 4.7 5 0 0 5 5 4 0 FG-GAP repeat DUF5114 PF17141.4 ETS77442.1 - 0.02 15.4 0.8 16 6.1 0.1 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF5114) WD40_like PF17005.5 ETS77442.1 - 0.028 13.7 7.1 9.9 5.4 0.1 4.8 2 2 2 5 5 5 0 WD40-like domain AAA PF00004.29 ETS77442.1 - 0.071 13.5 0.0 0.47 10.9 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ETS77442.1 - 0.1 12.3 0.5 0.91 9.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain KAP_NTPase PF07693.14 ETS77442.1 - 0.23 10.6 4.4 6.4 5.9 0.1 2.6 2 1 1 3 3 3 0 KAP family P-loop domain DUF1036 PF06282.11 ETS77442.1 - 0.6 10.7 3.5 44 4.7 0.0 4.7 3 2 2 5 5 5 0 Protein of unknown function (DUF1036) CDtoxinA PF03498.14 ETS77442.1 - 1.4 8.5 7.1 5.9 6.5 0.1 4.4 3 2 1 5 5 5 0 Cytolethal distending toxin A/C domain HET PF06985.11 ETS77443.1 - 1e-30 107.0 1.3 1.7e-30 106.3 1.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Gly_transf_sug PF04488.15 ETS77444.1 - 2.4e-09 37.7 0.1 5.4e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Peptidase_S8 PF00082.22 ETS77445.1 - 7.8e-06 25.4 0.5 0.013 14.8 0.1 3.3 2 1 0 2 2 2 2 Subtilase family EF-hand_6 PF13405.6 ETS77447.1 - 0.066 13.2 0.1 4.2 7.6 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain CAMP_factor PF07373.11 ETS77447.1 - 0.25 10.9 0.2 0.52 9.9 0.2 1.5 1 0 0 1 1 1 0 CAMP factor (Cfa) zf-Di19 PF05605.12 ETS77447.1 - 9.3 6.6 10.2 38 4.7 0.4 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-Sec23_Sec24 PF04810.15 ETS77447.1 - 10 6.3 6.7 50 4.1 0.3 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Spc7 PF08317.11 ETS77449.1 - 0.00013 20.9 4.5 0.00013 20.9 4.5 1.7 2 0 0 2 2 2 1 Spc7 kinetochore protein FAM184 PF15665.5 ETS77449.1 - 0.051 13.4 6.6 0.15 11.8 6.6 1.8 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B TMF_DNA_bd PF12329.8 ETS77449.1 - 0.17 11.9 6.8 0.33 11.0 1.2 3.4 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding CENP-Q PF13094.6 ETS77449.1 - 0.37 11.0 5.8 1.3 9.2 3.0 3.1 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit PKcGMP_CC PF16808.5 ETS77449.1 - 3 7.8 17.4 0.15 11.9 1.6 2.9 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TMF_TATA_bd PF12325.8 ETS77449.1 - 8.1 6.7 15.4 1.2 9.4 0.1 3.7 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding AKAP7_NLS PF10469.9 ETS77450.1 - 9.3e-29 100.8 0.0 1.3e-28 100.3 0.0 1.2 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 ETS77450.1 - 0.0004 20.3 0.1 0.00085 19.3 0.1 1.5 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily Hpt PF01627.23 ETS77451.1 - 5.2e-14 52.3 0.0 7.9e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Hpt domain DUF4783 PF16022.5 ETS77451.1 - 0.05 13.8 0.4 0.25 11.5 0.0 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4783) DUF3984 PF13136.6 ETS77452.1 - 1.3e-65 222.0 24.3 6.9e-65 219.6 24.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3984) cNMPbd_u2 PF16643.5 ETS77452.1 - 0.12 12.8 6.3 3.4 8.1 0.6 2.6 2 0 0 2 2 2 0 Unstructured region on cNMP-binding protein IKI3 PF04762.12 ETS77453.1 - 5e-295 981.3 0.0 6e-295 981.0 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 ETS77453.1 - 0.0014 18.8 0.1 2 8.8 0.0 4.2 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ETS77453.1 - 0.18 12.7 0.4 4.7e+02 1.9 0.0 5.0 5 0 0 5 5 5 0 WD domain, G-beta repeat KOW PF00467.29 ETS77454.1 - 0.00016 21.5 0.3 0.00043 20.1 0.3 1.7 1 0 0 1 1 1 1 KOW motif DUF4208 PF13907.6 ETS77454.1 - 0.052 14.0 0.2 0.11 13.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) Ras PF00071.22 ETS77455.1 - 1.6e-56 190.4 0.0 1.8e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS77455.1 - 8.3e-22 77.6 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS77455.1 - 3.8e-07 29.7 0.0 6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ETS77455.1 - 0.0015 18.0 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 ETS77455.1 - 0.019 14.1 0.1 0.18 11.0 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain baeRF_family3 PF18845.1 ETS77455.1 - 0.097 12.9 0.0 0.4 10.9 0.0 1.8 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 Gtr1_RagA PF04670.12 ETS77455.1 - 0.17 11.2 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Skp1 PF01466.19 ETS77455.1 - 0.17 12.0 0.8 0.88 9.7 0.1 2.4 3 0 0 3 3 3 0 Skp1 family, dimerisation domain Aa_trans PF01490.18 ETS77456.1 - 2.1e-74 250.7 29.1 2.6e-74 250.4 29.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NAD_binding_4 PF07993.12 ETS77458.1 - 2.6e-32 112.0 0.0 4.5e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 ETS77458.1 - 1.4e-23 83.2 0.0 2.1e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 ETS77458.1 - 3.1e-09 37.1 0.1 7.9e-09 35.7 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 ETS77458.1 - 1.2e-07 31.4 0.0 2.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Mre11_DNA_bind PF04152.14 ETS77459.1 - 1.8e-49 168.3 1.3 4.5e-49 167.0 1.3 1.7 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 ETS77459.1 - 5.4e-06 27.1 0.6 1.7e-05 25.4 0.7 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Tcp11 PF05794.13 ETS77460.1 - 1.7e-97 327.3 0.0 1.7e-97 327.3 0.0 2.7 3 0 0 3 3 3 1 T-complex protein 11 CENP-F_leu_zip PF10473.9 ETS77460.1 - 0.096 12.7 13.5 0.26 11.3 13.5 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Asp2 PF16929.5 ETS77460.1 - 1 8.3 3.3 26 3.6 0.3 2.9 3 0 0 3 3 3 0 Accessory Sec system GspB-transporter UPF0242 PF06785.11 ETS77460.1 - 4.8 7.2 11.4 13 5.8 11.4 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Y_phosphatase PF00102.27 ETS77461.1 - 3.1e-58 197.1 0.0 1.5e-50 172.0 0.0 3.3 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 ETS77461.1 - 2.5e-12 47.3 0.0 1.7e-11 44.6 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 ETS77461.1 - 0.063 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 ETS77461.1 - 0.093 12.5 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain AAA PF00004.29 ETS77462.1 - 7.6e-44 149.3 0.0 1.3e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ETS77462.1 - 1.4e-14 53.6 0.2 4.3e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 ETS77462.1 - 1.1e-07 31.9 0.0 2.7e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ETS77462.1 - 1.4e-07 31.8 0.0 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 ETS77462.1 - 1.6e-06 28.0 2.3 4.3e-06 26.6 2.3 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 ETS77462.1 - 4.3e-06 27.2 0.0 0.00011 22.6 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ETS77462.1 - 2.5e-05 24.6 0.2 0.006 16.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ETS77462.1 - 5.8e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 ETS77462.1 - 0.00064 20.3 0.1 0.019 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 ETS77462.1 - 0.001 18.4 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 ETS77462.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ETS77462.1 - 0.0028 17.4 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 ETS77462.1 - 0.0031 17.3 0.0 0.01 15.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 ETS77462.1 - 0.0081 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 ETS77462.1 - 0.0088 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 KaiC TsaE PF02367.17 ETS77462.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 ETS77462.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 ETS77462.1 - 0.016 14.8 0.1 0.06 13.0 0.1 2.0 1 1 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain DUF815 PF05673.13 ETS77462.1 - 0.022 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 ETS77462.1 - 0.023 14.4 0.0 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 ETS77462.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 ETS77462.1 - 0.03 13.8 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 ETS77462.1 - 0.032 13.9 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ETS77462.1 - 0.035 14.5 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 ETS77462.1 - 0.035 14.1 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ETS77462.1 - 0.043 13.4 0.1 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain HR1 PF02185.16 ETS77462.1 - 0.05 13.7 0.9 0.12 12.5 0.9 1.6 1 0 0 1 1 1 0 Hr1 repeat Parvo_NS1 PF01057.17 ETS77462.1 - 0.061 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 ETS77462.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2072 PF09845.9 ETS77462.1 - 0.14 12.4 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Na_Ca_ex PF01699.24 ETS77463.1 - 9.9e-21 74.3 30.0 3.4e-14 53.1 13.4 3.6 4 0 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 ETS77463.1 - 3.9e-17 62.7 10.6 3.9e-17 62.7 10.6 4.5 5 0 0 5 5 5 1 Inner membrane component domain CTP_transf_like PF01467.26 ETS77464.1 - 0.0085 16.3 0.0 0.044 14.0 0.0 2.0 2 0 0 2 2 2 1 Cytidylyltransferase-like UL73_N PF12522.8 ETS77464.1 - 4.3 7.2 12.8 13 5.6 12.8 1.9 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal ANAPC10 PF03256.16 ETS77465.1 - 1.6e-46 158.3 0.0 2.4e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) SDA1 PF05285.12 ETS77465.1 - 2.5 7.5 7.2 4.4 6.6 7.2 1.3 1 0 0 1 1 1 0 SDA1 ERAP1_C PF11838.8 ETS77466.1 - 6.7e-83 278.8 0.2 9.7e-82 275.0 0.1 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 ETS77466.1 - 5.6e-80 268.0 0.7 8.6e-80 267.4 0.7 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 ETS77466.1 - 2.8e-49 167.9 0.7 9.1e-48 162.9 0.3 2.5 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF45 PF01863.17 ETS77466.1 - 0.0047 17.0 0.0 0.098 12.7 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function DUF45 DUF2808 PF10989.8 ETS77466.1 - 0.0097 15.9 0.1 0.1 12.6 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2808) Peptidase_M50 PF02163.22 ETS77466.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M50 DUF3489 PF11994.8 ETS77466.1 - 0.11 12.6 0.0 6.4 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3489) KIP1 PF07765.12 ETS77467.1 - 1.5 9.0 5.0 14 5.9 1.4 2.9 3 0 0 3 3 3 0 KIP1-like protein DUF4404 PF14357.6 ETS77467.1 - 2.6 8.7 7.0 5.3 7.8 5.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TMF_TATA_bd PF12325.8 ETS77467.1 - 4.2 7.6 11.9 0.055 13.7 2.3 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding CBFD_NFYB_HMF PF00808.23 ETS77468.1 - 9.5e-05 22.6 0.2 0.00012 22.2 0.2 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 ETS77468.1 - 0.00043 20.4 0.0 0.00047 20.3 0.0 1.1 1 0 0 1 1 1 1 CENP-W protein JmjC PF02373.22 ETS77469.1 - 9.7e-37 125.9 0.4 3.2e-36 124.2 0.4 2.0 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 ETS77469.1 - 3.1e-20 72.4 4.3 5.3e-20 71.6 4.3 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 ETS77469.1 - 1.4e-19 70.2 3.7 3e-19 69.1 3.7 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.17 ETS77469.1 - 4.7e-13 48.9 0.9 9.3e-13 47.9 0.9 1.5 1 0 0 1 1 1 1 jmjN domain DUF3322 PF11795.8 ETS77469.1 - 0.0026 17.8 0.2 0.008 16.2 0.2 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria N-term (DUF3322) PGA2 PF07543.12 ETS77469.1 - 0.1 12.6 5.2 0.35 10.8 5.2 1.9 1 0 0 1 1 1 0 Protein trafficking PGA2 FAM176 PF14851.6 ETS77469.1 - 1.6 8.3 4.2 5.1 6.7 4.2 1.8 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 ETS77469.1 - 6.5 7.2 21.8 0.039 14.3 4.0 3.9 3 1 1 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal OB_NTP_bind PF07717.16 ETS77470.1 - 3.8e-24 84.8 0.2 4.2e-23 81.5 0.0 2.6 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 ETS77470.1 - 1.1e-18 67.5 0.0 2.8e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ETS77470.1 - 2.6e-11 43.8 0.0 1.5e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ETS77470.1 - 2.7e-08 33.8 0.1 8.1e-08 32.2 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ETS77470.1 - 2.3e-07 31.2 0.0 7.5e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 ETS77470.1 - 9.3e-05 22.1 0.1 0.00038 20.1 0.1 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 ETS77470.1 - 0.00063 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ETS77470.1 - 0.0021 18.4 0.1 0.004 17.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 ETS77470.1 - 0.0047 16.0 0.0 0.0094 15.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 ETS77470.1 - 0.024 14.6 0.2 0.052 13.5 0.2 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF2075 PF09848.9 ETS77470.1 - 0.026 13.8 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 ETS77470.1 - 0.062 13.8 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2183 PF09949.9 ETS77471.1 - 2.6e-23 82.2 0.1 1.2e-22 80.0 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) CSTF_C PF14304.6 ETS77471.1 - 0.15 11.6 0.2 0.33 10.6 0.2 1.5 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal Prefoldin_2 PF01920.20 ETS77472.1 - 6.8e-25 87.1 6.1 8.5e-25 86.8 6.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Syntaxin-6_N PF09177.11 ETS77472.1 - 0.0021 18.6 3.2 0.73 10.4 0.9 2.1 2 0 0 2 2 2 2 Syntaxin 6, N-terminal PI3K_P85_iSH2 PF16454.5 ETS77472.1 - 0.0057 16.3 6.1 0.02 14.5 6.1 1.7 1 1 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain AKNA PF12443.8 ETS77472.1 - 0.028 15.1 1.2 0.033 14.9 0.0 1.7 2 0 0 2 2 2 0 AT-hook-containing transcription factor FlaC_arch PF05377.11 ETS77472.1 - 0.08 13.3 0.4 0.08 13.3 0.4 2.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) PRMT5_TIM PF17285.2 ETS77473.1 - 2.5e-71 239.9 0.0 3.4e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 ETS77473.1 - 5.5e-68 228.2 0.0 9e-68 227.5 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 ETS77473.1 - 4.6e-61 205.8 0.0 7.9e-61 205.0 0.0 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 ETS77473.1 - 0.036 13.8 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein LSM PF01423.22 ETS77474.1 - 1.9e-19 69.1 0.1 2.1e-19 68.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF866 PF05907.13 ETS77475.1 - 2.2e-61 206.3 1.8 2.7e-61 206.0 1.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) PHD PF00628.29 ETS77475.1 - 0.039 13.8 0.6 0.08 12.9 0.6 1.6 1 0 0 1 1 1 0 PHD-finger zf-DNL PF05180.12 ETS77475.1 - 0.061 13.3 1.7 3.6 7.6 0.2 2.4 2 0 0 2 2 2 0 DNL zinc finger Zn_ribbon_SprT PF17283.2 ETS77475.1 - 0.067 13.1 3.0 2.7 8.0 0.1 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain HalOD2 PF18547.1 ETS77475.1 - 0.074 13.0 1.3 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 Halobacterial output domain 2 RNHCP PF12647.7 ETS77475.1 - 0.19 11.7 2.0 12 6.0 0.1 2.2 1 1 1 2 2 2 0 RNHCP domain DUF4379 PF14311.6 ETS77475.1 - 1 9.8 6.5 0.22 11.9 1.3 2.2 1 1 1 2 2 2 0 Probable Zinc-ribbon domain Dsl1_N PF11988.8 ETS77476.1 - 0.061 12.3 0.1 0.1 11.5 0.1 1.3 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal GDPD PF03009.17 ETS77477.1 - 5.3e-69 232.8 0.0 1e-68 231.9 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 ETS77477.1 - 2e-27 95.6 1.4 4.1e-09 36.9 0.1 4.3 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS77477.1 - 1.4e-26 92.5 2.9 1.7e-08 34.8 0.1 5.6 5 0 0 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.19 ETS77477.1 - 5.8e-24 85.7 5.8 6e-12 46.2 0.0 3.5 2 1 1 3 3 3 3 SPX domain Ank_5 PF13857.6 ETS77477.1 - 5e-21 74.5 0.7 3.2e-08 33.7 0.0 6.1 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS77477.1 - 7.3e-17 59.8 2.7 0.0028 18.0 0.0 7.2 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 ETS77477.1 - 1.9e-14 53.3 11.4 0.00044 20.6 0.1 6.7 7 0 0 7 7 7 3 Ankyrin repeat DUF1978 PF09321.10 ETS77477.1 - 0.012 14.9 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) Peptidase_M41 PF01434.18 ETS77478.1 - 1.3e-56 191.5 1.6 2.1e-56 190.8 1.6 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 ETS77478.1 - 9.2e-43 145.8 0.0 2.2e-42 144.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ETS77478.1 - 6e-10 38.8 0.0 1.2e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 ETS77478.1 - 6.6e-06 26.2 0.0 3.4e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ETS77478.1 - 5.3e-05 22.6 0.0 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 ETS77478.1 - 0.00012 22.4 0.2 0.063 13.5 0.0 3.3 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 ETS77478.1 - 0.00013 22.4 4.9 0.00052 20.4 0.8 3.8 3 1 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 ETS77478.1 - 0.00013 21.8 0.0 0.0021 17.8 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 ETS77478.1 - 0.004 17.3 0.0 0.015 15.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ETS77478.1 - 0.0094 15.7 0.0 0.031 14.0 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 ETS77478.1 - 0.017 14.9 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 ETS77478.1 - 0.025 14.0 0.3 0.056 12.8 0.3 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 ETS77478.1 - 0.043 13.4 1.0 0.83 9.2 0.3 2.4 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 ETS77478.1 - 0.066 13.8 0.0 0.25 11.9 0.0 2.1 3 0 0 3 3 1 0 AAA domain AAA_7 PF12775.7 ETS77478.1 - 0.083 12.4 0.1 0.4 10.2 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 ETS77478.1 - 0.086 13.1 0.0 0.28 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 ETS77478.1 - 0.086 13.0 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) SpoU_sub_bind PF08032.12 ETS77478.1 - 0.14 12.5 0.2 15 6.0 0.0 3.3 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding AAA_14 PF13173.6 ETS77478.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 ETS77478.1 - 0.15 12.5 0.0 0.45 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ETS77478.1 - 0.16 11.2 0.8 0.55 9.5 0.4 2.0 1 1 1 2 2 2 0 Zeta toxin NACHT PF05729.12 ETS77478.1 - 0.53 10.2 2.5 1.9 8.3 0.1 2.8 3 0 0 3 3 3 0 NACHT domain Ufd2P_core PF10408.9 ETS77479.1 - 3.8e-208 693.1 7.6 4.7e-208 692.8 7.6 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 ETS77479.1 - 1.5e-21 76.3 0.7 5.4e-21 74.6 0.7 2.0 1 0 0 1 1 1 1 U-box domain DUF4777 PF16007.5 ETS77479.1 - 0.018 15.3 0.0 0.091 13.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) PEP-utilisers_N PF05524.13 ETS77479.1 - 0.1 12.8 1.5 5.6 7.2 0.2 3.1 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal DUF4164 PF13747.6 ETS77479.1 - 0.15 12.4 1.9 0.88 9.9 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) EF-1_beta_acid PF10587.9 ETS77479.1 - 0.51 10.8 3.2 19 5.8 0.0 2.6 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Epimerase PF01370.21 ETS77481.1 - 1e-19 71.0 0.0 1.5e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS77481.1 - 8.4e-13 47.9 0.0 1.2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ETS77481.1 - 1.1e-10 41.7 0.0 2.1e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ETS77481.1 - 6.8e-10 38.9 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ETS77481.1 - 3.3e-09 36.3 0.0 7.5e-08 31.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ETS77481.1 - 4.3e-05 22.8 0.0 6.1e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 ETS77481.1 - 0.00032 20.2 0.0 0.00058 19.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS77481.1 - 0.00037 20.4 0.0 0.00067 19.6 0.0 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 ETS77481.1 - 0.002 18.6 0.0 0.0067 17.0 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 ETS77481.1 - 0.0093 16.2 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 ETS77481.1 - 0.015 14.9 0.1 0.033 13.8 0.1 1.7 1 1 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 ETS77481.1 - 0.021 13.9 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short_C2 PF13561.6 ETS77481.1 - 0.046 13.3 0.1 0.081 12.5 0.1 1.4 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase zf-C2H2 PF00096.26 ETS77482.1 - 1.7e-20 72.2 29.7 1e-05 25.7 0.1 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ETS77482.1 - 5.7e-18 64.5 27.9 2.1e-06 27.9 0.6 5.1 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 ETS77482.1 - 4.8e-09 36.3 27.0 0.022 15.6 1.9 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ETS77482.1 - 0.0065 16.7 9.8 0.73 10.2 7.0 2.7 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ETS77482.1 - 0.0072 16.6 9.1 0.34 11.3 0.3 4.1 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ETS77482.1 - 0.0078 16.8 9.9 5 7.8 0.3 4.8 2 1 2 4 4 4 1 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 ETS77482.1 - 0.015 15.1 2.0 0.015 15.1 2.0 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 ETS77482.1 - 0.062 13.7 0.5 0.062 13.7 0.5 4.5 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-TRAF PF02176.18 ETS77482.1 - 0.9 10.3 19.4 0.073 13.8 2.8 3.6 2 1 2 4 4 4 0 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 ETS77482.1 - 8.6 6.5 11.6 3.6 7.7 0.1 3.4 1 1 2 3 3 3 0 Aberrant zinc-finger Macoilin PF09726.9 ETS77484.1 - 0.25 9.9 2.2 0.26 9.8 2.2 1.2 1 0 0 1 1 1 0 Macoilin family Glyco_trans_2_3 PF13632.6 ETS77485.1 - 0.014 15.3 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Mfa1 PF17445.2 ETS77485.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Mating factor A1 DOCK_N PF16172.5 ETS77486.1 - 9.1e-128 426.4 0.0 1.5e-127 425.7 0.0 1.3 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 ETS77486.1 - 3.8e-33 114.9 0.0 1.1e-32 113.5 0.0 1.8 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 ETS77486.1 - 9.1e-32 110.4 2.8 3.9e-31 108.3 2.8 1.8 1 1 0 1 1 1 1 Dock homology region 2 SH3_1 PF00018.28 ETS77486.1 - 9.3e-05 22.0 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ETS77486.1 - 0.00036 20.3 0.0 0.0016 18.2 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain VTC PF09359.10 ETS77487.1 - 2.9e-90 302.4 3.2 2.9e-90 302.4 3.2 1.7 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 ETS77487.1 - 9.3e-12 45.2 1.7 9.3e-12 45.2 1.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 ETS77487.1 - 7.3e-09 36.0 3.4 3.2e-05 24.0 0.6 4.2 3 1 1 5 5 5 2 SPX domain TBCC_N PF16752.5 ETS77487.1 - 0.039 14.4 6.7 0.062 13.7 0.5 2.7 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Noelin-1 PF12308.8 ETS77487.1 - 0.091 12.8 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Neurogenesis glycoprotein Phage_HK97_TLTM PF06120.11 ETS77487.1 - 4.3 6.4 7.4 1.1 8.4 0.5 2.3 2 0 0 2 2 2 0 Tail length tape measure protein Bac_rhodopsin PF01036.18 ETS77488.1 - 0.0017 18.0 22.6 0.0091 15.6 22.6 1.8 1 1 0 1 1 1 1 Bacteriorhodopsin-like protein Use1 PF09753.9 ETS77490.1 - 0.0017 18.1 0.5 0.0018 18.0 0.5 1.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 Apc15p PF05841.11 ETS77491.1 - 1.1e-23 84.3 4.9 2.6e-23 83.2 4.9 1.6 1 0 0 1 1 1 1 Apc15p protein GATase_2 PF00310.21 ETS77492.1 - 8.8e-183 607.8 0.0 1.3e-182 607.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 ETS77492.1 - 1.4e-156 521.3 0.0 2.2e-156 520.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 ETS77492.1 - 1.6e-110 369.0 0.0 4.2e-109 364.4 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 ETS77492.1 - 1.8e-86 288.6 3.9 3.5e-86 287.7 3.9 1.5 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 ETS77492.1 - 7e-23 81.3 0.1 5.4e-22 78.4 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 ETS77492.1 - 1.5e-21 76.2 0.1 3e-21 75.3 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 ETS77492.1 - 1.4e-07 31.6 0.0 4.7e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS77492.1 - 8.7e-07 28.8 0.7 0.0011 18.7 0.3 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS77492.1 - 1.3e-06 28.9 0.1 0.0017 18.9 0.1 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ETS77492.1 - 1.6e-05 24.4 0.1 2.8e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 ETS77492.1 - 0.0003 19.6 0.1 0.0003 19.6 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 ETS77492.1 - 0.00031 20.1 0.9 0.51 9.5 0.0 3.6 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ETS77492.1 - 0.00036 20.0 0.2 0.00075 19.0 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS77492.1 - 0.00041 19.6 0.1 0.0027 16.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 ETS77492.1 - 0.0034 17.8 1.1 3.7 8.0 0.1 2.8 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_3 PF01494.19 ETS77492.1 - 0.0036 16.6 0.1 0.0078 15.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 ETS77492.1 - 0.0042 16.4 0.2 0.58 9.4 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FMN_dh PF01070.18 ETS77492.1 - 0.021 13.9 0.8 0.12 11.4 0.6 2.2 3 0 0 3 3 3 0 FMN-dependent dehydrogenase Thi4 PF01946.17 ETS77492.1 - 0.027 13.7 0.1 0.083 12.1 0.1 1.8 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 ETS77492.1 - 0.069 12.2 1.0 0.21 10.6 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.23 ETS77492.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Lycopene_cycl PF05834.12 ETS77492.1 - 0.11 11.5 0.1 1.5 7.8 0.1 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein Relaxase PF03432.14 ETS77492.1 - 0.22 11.1 1.4 0.48 10.0 1.4 1.5 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Arm PF00514.23 ETS77493.1 - 2.3e-06 27.4 28.3 0.45 10.6 0.8 9.1 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 ETS77493.1 - 4.6e-06 26.1 0.1 0.051 12.9 0.0 3.6 3 2 1 4 4 4 2 V-ATPase subunit H HEAT_EZ PF13513.6 ETS77493.1 - 0.00063 20.2 13.8 0.31 11.6 0.2 6.2 6 0 0 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 ETS77493.1 - 0.0015 18.9 17.7 0.16 12.3 0.2 7.3 7 2 1 8 8 8 2 HEAT repeats HEAT PF02985.22 ETS77493.1 - 0.0066 16.6 21.6 4.4 7.8 0.1 8.5 9 0 0 9 9 9 2 HEAT repeat DUF3361 PF11841.8 ETS77493.1 - 0.015 15.2 3.0 37 4.2 0.1 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF3361) Cyclin PF08613.11 ETS77494.1 - 1.2e-30 107.1 1.1 4e-30 105.3 0.0 2.2 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 ETS77494.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain CHZ PF09649.10 ETS77496.1 - 5.8e-16 57.7 1.0 5.8e-16 57.7 1.0 2.2 2 0 0 2 2 2 1 Histone chaperone domain CHZ PPP4R2 PF09184.11 ETS77496.1 - 9.6 5.7 14.0 12 5.4 14.0 1.2 1 0 0 1 1 1 0 PPP4R2 Velvet PF11754.8 ETS77497.1 - 5.1e-51 174.0 7.8 2.9e-33 115.9 0.0 3.1 2 2 1 3 3 3 2 Velvet factor Ank_5 PF13857.6 ETS77499.1 - 2.7e-13 49.8 0.0 1.5e-10 41.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS77499.1 - 4.6e-13 49.0 0.4 1.2e-06 28.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat TIG PF01833.24 ETS77499.1 - 1.1e-11 44.6 0.6 1.1e-11 44.6 0.6 2.5 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.7 ETS77499.1 - 1.7e-10 41.3 0.0 3.7e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS77499.1 - 1.6e-09 38.1 0.0 1.7e-07 31.6 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS77499.1 - 1.5e-08 34.2 0.1 0.00016 21.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat RHD_dimer PF16179.5 ETS77499.1 - 0.0027 17.7 0.0 0.008 16.2 0.0 1.9 1 0 0 1 1 1 1 Rel homology dimerisation domain DnaJ PF00226.31 ETS77499.1 - 0.06 13.5 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 DnaJ domain Na_H_Exchanger PF00999.21 ETS77500.1 - 1.4e-44 152.5 20.1 1.8e-44 152.1 20.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Cauli_VI PF01693.16 ETS77501.1 - 3.1e-38 129.8 9.5 4.6e-21 74.8 0.3 2.3 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 ETS77501.1 - 1.7e-34 119.1 0.3 3e-34 118.3 0.0 1.5 2 0 0 2 2 2 1 RNase H Lip_prot_lig_C PF10437.9 ETS77501.1 - 0.024 14.6 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus dCMP_cyt_deam_1 PF00383.23 ETS77502.1 - 1.3e-09 37.8 0.0 3.7e-09 36.4 0.0 1.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ETS77502.1 - 6.2e-05 22.8 0.2 0.00019 21.2 0.1 1.8 2 0 0 2 2 2 1 MafB19-like deaminase Bd3614-deam PF14439.6 ETS77502.1 - 0.038 14.1 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase 6PF2K PF01591.18 ETS77503.1 - 2.4e-65 220.0 0.0 6.7e-45 153.1 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ETS77503.1 - 8e-27 94.2 0.1 1.2e-20 74.0 0.0 2.6 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 ETS77503.1 - 0.004 17.3 0.2 0.087 13.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 ETS77503.1 - 0.034 13.6 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 HATPase_c PF02518.26 ETS77504.1 - 3.5e-26 91.9 0.8 3.5e-26 91.9 0.8 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ETS77504.1 - 1.9e-20 73.1 0.0 7.7e-20 71.1 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain PAS_3 PF08447.12 ETS77504.1 - 8.8e-20 70.8 2.3 3.7e-10 40.0 0.8 3.7 3 0 0 3 3 3 3 PAS fold HisKA PF00512.25 ETS77504.1 - 1.7e-19 69.6 0.1 3.7e-19 68.5 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 ETS77504.1 - 1.3e-07 31.8 0.0 0.058 13.7 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 ETS77504.1 - 1.7e-07 31.4 0.1 4.5e-06 26.9 0.1 2.6 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 ETS77504.1 - 6.6e-06 26.1 0.0 0.14 12.2 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 ETS77504.1 - 0.00043 20.2 0.0 0.056 13.5 0.0 2.6 2 0 0 2 2 2 1 PAS domain DUF1445 PF07286.12 ETS77505.1 - 1.4e-57 193.6 0.0 3.3e-57 192.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1445) Fungal_trans PF04082.18 ETS77506.1 - 1.6e-27 96.2 0.2 2.7e-27 95.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DIL PF01843.19 ETS77507.1 - 8.5e-31 106.3 0.2 1.8e-30 105.3 0.2 1.6 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 ETS77507.1 - 1.5e-13 51.1 0.0 3.9e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS77507.1 - 2.8e-11 43.7 0.0 2.9e-05 24.5 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ETS77507.1 - 1.3e-09 38.1 0.4 0.0028 18.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ETS77507.1 - 1e-08 35.2 0.1 4.6e-07 30.0 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS77507.1 - 5.8e-05 23.2 0.0 0.35 11.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Allantoicase PF03561.15 ETS77508.1 - 1e-93 310.9 0.0 3.1e-46 156.9 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Cytochrom_B561 PF03188.16 ETS77509.1 - 2.7e-19 69.7 5.1 4.3e-19 69.0 5.1 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 ETS77509.1 - 1.2 9.2 13.3 15 5.8 8.7 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF4079) PepSY_TM PF03929.16 ETS77509.1 - 3.9 7.0 9.0 6.1 6.4 6.4 2.4 1 1 0 1 1 1 0 PepSY-associated TM region RabGAP-TBC PF00566.18 ETS77510.1 - 3.2e-37 128.3 0.1 6e-37 127.4 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Peptidase_S64 PF08192.11 ETS77510.1 - 0.048 12.2 1.7 0.067 11.7 1.7 1.3 1 0 0 1 1 1 0 Peptidase family S64 Sulfotransfer_3 PF13469.6 ETS77511.1 - 2.9 8.2 7.1 0.31 11.4 2.2 1.8 2 0 0 2 2 2 0 Sulfotransferase family Spindle_Spc25 PF08234.12 ETS77512.1 - 0.0035 17.5 0.2 0.26 11.5 0.1 2.6 2 0 0 2 2 2 2 Chromosome segregation protein Spc25 AAA PF00004.29 ETS77513.1 - 3.2e-18 66.4 0.0 2.8e-17 63.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS77513.1 - 3.2e-05 24.2 1.2 0.00022 21.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS77513.1 - 0.0011 19.4 0.1 0.0046 17.4 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ETS77513.1 - 0.012 15.6 0.0 0.035 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zot PF05707.12 ETS77513.1 - 0.03 13.9 0.1 0.27 10.9 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) RuvB_N PF05496.12 ETS77513.1 - 0.046 13.5 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NB-ARC PF00931.22 ETS77513.1 - 0.048 12.8 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 ETS77513.1 - 0.049 13.8 0.0 0.14 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ETS77513.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain HATPase_c PF02518.26 ETS77514.1 - 7.9e-30 103.7 0.1 1.9e-29 102.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ETS77514.1 - 2.7e-20 72.6 0.3 6.2e-20 71.4 0.3 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ETS77514.1 - 8.2e-18 64.2 1.8 1.4e-17 63.4 0.3 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 ETS77514.1 - 1.6e-11 44.9 2.6 7.2e-11 42.8 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain GAF_2 PF13185.6 ETS77514.1 - 1.1e-09 38.7 0.0 3.8e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 ETS77514.1 - 1.4e-06 27.9 0.0 3.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF PF01590.26 ETS77514.1 - 2.5e-06 28.1 0.0 7.1e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 ETS77514.1 - 0.00047 20.0 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase_Tyr PF07714.17 ETS77514.1 - 0.00049 19.5 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NACHT PF05729.12 ETS77514.1 - 0.032 14.1 0.2 3.6 7.5 0.0 3.1 3 0 0 3 3 3 0 NACHT domain NB-ARC PF00931.22 ETS77514.1 - 0.099 11.8 0.0 0.25 10.5 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AP1AR PF15745.5 ETS77514.1 - 0.13 11.9 1.6 0.24 11.0 1.6 1.3 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein NBD94 PF16830.5 ETS77514.1 - 0.13 12.6 0.1 3.7 8.0 0.0 2.7 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH Amino_oxidase PF01593.24 ETS77515.1 - 4.5e-09 36.1 0.0 6.6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ETS77515.1 - 2.1e-08 34.3 0.1 4.3e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS77515.1 - 0.00019 20.7 0.1 0.034 13.4 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS77515.1 - 0.0042 16.4 0.2 0.0082 15.4 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS77515.1 - 0.006 15.9 0.2 0.014 14.7 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 ETS77515.1 - 0.014 14.6 0.1 0.032 13.5 0.1 1.6 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 ETS77515.1 - 0.019 13.7 0.1 0.04 12.6 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 ETS77515.1 - 0.024 14.9 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain FAD_oxidored PF12831.7 ETS77515.1 - 0.07 12.5 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 ETS77515.1 - 0.077 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ETS77515.1 - 0.087 11.9 0.5 0.17 10.9 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein TPT PF03151.16 ETS77516.1 - 5e-26 91.7 23.4 6.6e-26 91.3 23.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Ribosomal_L27e PF01777.18 ETS77517.1 - 2.4e-37 127.1 5.1 3.6e-37 126.6 5.1 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 ETS77517.1 - 0.0037 17.2 0.7 0.011 15.7 0.7 1.8 1 0 0 1 1 1 1 KOW motif TPR_17 PF13431.6 ETS77518.1 - 0.01 16.2 0.4 0.19 12.2 0.4 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat FeoB_Cyto PF17910.1 ETS77518.1 - 0.16 12.5 0.5 0.56 10.8 0.1 2.0 2 0 0 2 2 2 0 FeoB cytosolic helical domain Glyoxalase PF00903.25 ETS77519.1 - 7.2e-25 87.6 0.8 7.4e-17 61.7 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ETS77519.1 - 3.1e-13 49.9 0.2 7.7e-06 26.2 0.2 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 ETS77519.1 - 1.2e-05 25.6 0.1 0.2 11.7 0.0 3.1 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 ETS77519.1 - 0.026 14.7 0.2 0.079 13.1 0.0 1.8 2 0 0 2 2 2 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Ssl1 PF04056.14 ETS77520.1 - 4.8e-74 248.4 0.0 6.3e-74 248.0 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 ETS77520.1 - 8.3e-20 70.8 9.7 8.3e-20 70.8 9.7 2.8 3 0 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.6 ETS77520.1 - 9.6e-14 51.9 0.0 2.1e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 ETS77520.1 - 0.003 17.8 0.0 0.0048 17.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zinc_ribbon_15 PF17032.5 ETS77520.1 - 3.5 8.5 15.7 0.11 13.2 5.4 2.5 1 1 1 2 2 2 0 zinc-ribbon family zf-CRD PF17979.1 ETS77520.1 - 3.8 7.6 13.5 0.63 10.1 4.0 2.4 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions Glyoxalase_4 PF13669.6 ETS77521.1 - 5.9e-14 52.3 0.0 8e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pec_lyase_C PF00544.19 ETS77522.1 - 4.1e-37 127.8 6.0 5.7e-37 127.4 6.0 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 ETS77522.1 - 2.6e-05 24.1 13.1 0.00018 21.4 10.2 2.4 2 1 0 2 2 2 1 Right handed beta helix region DUF4955 PF16315.5 ETS77522.1 - 0.095 12.9 0.7 1.6 8.9 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4955) Choline_transpo PF04515.12 ETS77523.1 - 5.3e-30 104.7 12.1 5.3e-30 104.7 12.1 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter Ras PF00071.22 ETS77524.1 - 8.2e-50 168.6 0.1 1.2e-48 164.8 0.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 ETS77524.1 - 1.1e-29 103.1 0.0 5.4e-19 68.6 0.0 2.2 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS77524.1 - 4.6e-11 42.5 0.0 1.7e-10 40.7 0.1 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ETS77524.1 - 4.6e-06 26.3 0.0 1.5e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ETS77524.1 - 8.2e-06 25.3 0.0 1.3e-05 24.7 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ETS77524.1 - 9.7e-05 22.4 0.0 0.00024 21.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETS77524.1 - 0.0016 18.4 0.7 0.65 9.9 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 ETS77524.1 - 0.017 14.9 0.1 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 ETS77524.1 - 0.078 13.2 0.2 0.47 10.7 0.2 2.1 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 ETS77524.1 - 0.082 11.9 0.2 0.15 11.0 0.1 1.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 ETS77524.1 - 0.12 11.9 0.1 16 5.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain PMT PF02366.18 ETS77525.1 - 3.9e-81 272.3 15.3 3.9e-81 272.3 15.3 2.2 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ETS77525.1 - 1.6e-65 220.4 16.3 1.6e-65 220.4 16.3 2.0 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ETS77525.1 - 1.1e-37 129.6 0.1 1.8e-37 129.0 0.1 1.2 1 0 0 1 1 1 1 MIR domain Sugar_tr PF00083.24 ETS77526.1 - 2e-103 346.7 11.9 2.4e-103 346.4 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS77526.1 - 5.5e-27 94.6 34.5 1.7e-26 93.0 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS77526.1 - 1.1e-06 27.5 16.1 3.6e-05 22.5 0.6 3.0 4 0 0 4 4 4 2 MFS/sugar transport protein MFS_5 PF05631.14 ETS77526.1 - 0.003 16.6 0.2 0.0056 15.6 0.2 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 ETS77526.1 - 0.0053 15.7 2.9 0.48 9.2 1.0 2.3 1 1 1 2 2 2 2 MFS_1 like family Chs7 PF12271.8 ETS77527.1 - 8.9e-113 376.4 8.3 1.1e-112 376.1 8.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone adh_short PF00106.25 ETS77528.1 - 7.3e-25 87.6 0.0 1.2e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS77528.1 - 3.3e-14 53.0 0.0 5.4e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.8 ETS77528.1 - 0.093 12.5 0.2 0.26 11.1 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase WW PF00397.26 ETS77529.1 - 2.1e-11 43.7 6.1 3.9e-11 42.8 6.1 1.5 1 0 0 1 1 1 1 WW domain DUF2012 PF09430.10 ETS77530.1 - 1.9e-24 86.1 0.0 2.7e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) TctA PF01970.16 ETS77530.1 - 0.065 11.9 3.0 2.8 6.5 0.1 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctA family Cys_Met_Meta_PP PF01053.20 ETS77531.1 - 2.7e-147 490.3 0.0 3.1e-147 490.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ETS77531.1 - 3.3e-10 39.7 0.0 5.6e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ETS77531.1 - 5.2e-09 35.9 0.1 9.2e-09 35.1 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ETS77531.1 - 2.1e-08 33.6 0.4 3.6e-08 32.8 0.4 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ETS77531.1 - 1.4e-07 31.1 0.0 2.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 ETS77531.1 - 0.0017 16.9 0.1 0.0023 16.5 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 ETS77531.1 - 0.0018 17.1 0.0 0.0026 16.6 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Ribosomal_60s PF00428.19 ETS77531.1 - 0.065 13.8 5.1 1.9 9.1 0.4 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein MARVEL PF01284.23 ETS77532.1 - 7.9e-21 74.6 15.3 9.4e-21 74.4 15.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain MadM PF03818.13 ETS77532.1 - 0.075 12.9 5.1 2 8.3 0.2 2.3 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit AMP-binding PF00501.28 ETS77533.1 - 3.7e-88 295.9 0.0 4.5e-88 295.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme WD40 PF00400.32 ETS77534.1 - 6.2e-08 33.2 6.2 0.91 10.5 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS77534.1 - 0.039 14.3 0.1 12 6.3 0.1 3.7 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WDCP PF15390.6 ETS77534.1 - 0.11 10.8 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Siah-Interact_N PF09032.11 ETS77534.1 - 0.18 12.1 0.6 1.2 9.5 0.1 2.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal CTD_bind PF04818.13 ETS77535.1 - 1.1e-09 39.0 0.0 4.5e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 ETS77535.1 - 8.4e-07 28.7 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Citrate_synt PF00285.21 ETS77536.1 - 5.2e-99 331.7 0.0 7.2e-99 331.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 ETS77536.1 - 0.057 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.27 ETS77537.1 - 4.2e-28 97.1 4.1 7.8e-13 48.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein E1-E2_ATPase PF00122.20 ETS77538.1 - 1.1e-49 168.5 4.3 1.1e-49 168.5 4.3 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 ETS77538.1 - 5.5e-17 62.8 0.3 1.7e-16 61.1 0.3 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ETS77538.1 - 3.2e-10 39.5 0.0 7.1e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ETS77538.1 - 0.017 14.9 0.1 0.017 14.9 0.1 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase SPATIAL PF15256.6 ETS77538.1 - 0.23 11.8 0.4 0.41 11.0 0.4 1.3 1 0 0 1 1 1 0 SPATIAL ABM PF03992.16 ETS77539.1 - 0.00038 20.5 0.1 0.00048 20.2 0.1 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF1857 PF08982.11 ETS77541.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) FGGY_C PF02782.16 ETS77542.1 - 1.1e-50 172.2 1.4 1.8e-50 171.4 1.4 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 ETS77542.1 - 8.2e-23 81.2 0.4 6e-20 71.9 0.1 2.9 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 ETS77542.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Hexokinase Nic96 PF04097.14 ETS77543.1 - 1.7e-223 743.6 0.0 2.1e-223 743.3 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 ETS77543.1 - 2e-11 44.6 84.4 7.3e-07 29.9 38.9 4.8 2 1 2 4 4 4 3 Nucleoporin FG repeat region DUF3425 PF11905.8 ETS77544.1 - 1.4e-17 63.8 1.4 2.5e-17 63.0 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 ETS77544.1 - 0.0042 17.2 5.6 0.0094 16.0 5.5 1.6 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ETS77544.1 - 2.2 8.5 8.0 3.2 7.9 6.9 1.9 1 1 0 1 1 1 0 Basic region leucine zipper CFEM PF05730.11 ETS77545.1 - 8.6e-09 35.4 7.4 2.4e-08 34.0 7.4 1.7 1 0 0 1 1 1 1 CFEM domain Ribonuc_red_lgC PF02867.15 ETS77546.1 - 9.7e-193 641.4 0.0 1.3e-192 641.0 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 ETS77546.1 - 3.5e-24 84.6 0.0 2.3e-23 82.0 0.0 2.3 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 ETS77546.1 - 4.6e-17 62.4 0.0 9.1e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 ATP cone domain TatD_DNase PF01026.21 ETS77547.1 - 4.4e-44 150.8 0.1 3.5e-43 147.8 0.1 2.0 1 1 0 1 1 1 1 TatD related DNase K_channel_TID PF07941.11 ETS77547.1 - 4.3 7.9 8.9 9.7 6.7 8.9 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain CENP-N PF05238.13 ETS77548.1 - 2.3e-136 455.4 0.0 2.7e-136 455.2 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.15 ETS77550.1 - 1e-11 44.7 14.1 1.5e-11 44.2 14.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ETS77550.1 - 6.8e-05 22.9 9.5 0.00011 22.2 9.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor GIT_CC PF16559.5 ETS77550.1 - 0.0068 16.2 2.0 0.0073 16.2 0.6 1.7 2 0 0 2 2 2 1 GIT coiled-coil Rho guanine nucleotide exchange factor TPR_MLP1_2 PF07926.12 ETS77550.1 - 0.013 15.5 7.0 0.021 14.9 7.0 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TSC22 PF01166.18 ETS77550.1 - 0.015 15.6 0.8 0.028 14.7 0.8 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family XhlA PF10779.9 ETS77550.1 - 0.023 14.9 2.8 0.041 14.1 2.8 1.4 1 0 0 1 1 1 0 Haemolysin XhlA LCD1 PF09798.9 ETS77550.1 - 0.032 12.8 2.5 0.031 12.8 2.5 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein betaPIX_CC PF16523.5 ETS77550.1 - 0.035 13.9 1.4 0.037 13.9 0.7 1.5 1 1 0 1 1 1 0 betaPIX coiled coil Phlebovirus_NSM PF07246.11 ETS77550.1 - 0.23 10.8 3.2 0.3 10.4 3.2 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FapA PF03961.13 ETS77550.1 - 0.71 8.4 4.8 1.2 7.7 4.6 1.5 1 1 1 2 2 2 0 Flagellar Assembly Protein A PBP PF01161.20 ETS77551.1 - 1.3e-14 54.6 0.0 2.3e-14 53.8 0.0 1.4 1 1 1 2 2 2 1 Phosphatidylethanolamine-binding protein BRO1 PF03097.18 ETS77552.1 - 1.7e-125 418.9 0.3 2.8e-125 418.2 0.3 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 ETS77552.1 - 7.2e-82 275.0 6.3 7.2e-82 275.0 6.3 2.4 4 0 0 4 4 4 1 ALIX V-shaped domain binding to HIV Cep57_CLD_2 PF14197.6 ETS77552.1 - 0.095 12.8 5.1 0.3 11.2 1.2 3.6 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Patatin PF01734.22 ETS77553.1 - 2.8e-18 66.8 0.0 5.1e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase ABC_tran PF00005.27 ETS77553.1 - 0.0038 17.8 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ETS77553.1 - 0.0056 16.6 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 ETS77553.1 - 0.011 15.8 0.0 0.032 14.3 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 ETS77553.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-C3HC4_3 PF13920.6 ETS77553.1 - 0.1 12.5 23.2 0.81 9.6 8.9 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS77553.1 - 0.29 11.2 11.4 0.92 9.6 11.4 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 ETS77553.1 - 3.8 7.9 25.0 1.2 9.5 9.9 2.6 2 0 0 2 2 2 0 Ring finger domain Pro_CA PF00484.19 ETS77554.1 - 8.3e-52 175.6 0.0 1.1e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase DUF604 PF04646.12 ETS77555.1 - 1.1e-10 41.3 0.1 9.4e-09 35.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF604 Fringe PF02434.16 ETS77555.1 - 2e-07 30.7 0.0 3.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Fringe-like Rep-A_N PF04057.12 ETS77556.1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain Transferase PF02458.15 ETS77557.1 - 2.6e-11 42.8 0.0 1.7e-10 40.1 0.0 2.3 1 1 0 1 1 1 1 Transferase family Exo_endo_phos PF03372.23 ETS77558.1 - 4.4e-07 29.7 0.3 8.9e-07 28.6 0.3 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Gpr1_Fun34_YaaH PF01184.19 ETS77559.1 - 1.1e-15 57.8 12.3 1.6e-15 57.3 12.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family YfhO PF09586.10 ETS77559.1 - 0.13 10.5 0.5 0.15 10.2 0.5 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO P21-Arc PF04062.14 ETS77561.1 - 1.7e-69 233.4 0.0 1.9e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Gcd10p PF04189.13 ETS77562.1 - 4.2e-116 387.3 0.0 5.2e-116 387.0 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family Tcp11 PF05794.13 ETS77563.1 - 4.9e-108 362.1 1.5 7.9e-108 361.4 1.5 1.2 1 0 0 1 1 1 1 T-complex protein 11 TFIID-18kDa PF02269.16 ETS77564.1 - 1.6e-19 69.7 0.0 2.4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 ETS77564.1 - 0.038 14.0 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 ETS77564.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold EamA PF00892.20 ETS77565.1 - 2.6e-20 73.0 15.2 5.1e-12 46.1 0.7 2.4 2 1 0 2 2 2 2 EamA-like transporter family Trp_oprn_chp PF09534.10 ETS77565.1 - 0.00032 20.6 0.6 0.74 9.6 0.4 2.3 2 0 0 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PrgI PF12666.7 ETS77565.1 - 1.4 9.7 5.8 0.93 10.3 2.4 2.5 2 0 0 2 2 2 0 PrgI family protein Formyl_trans_N PF00551.19 ETS77567.1 - 1.6e-37 129.0 0.1 1.9e-37 128.7 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase Band_7 PF01145.25 ETS77568.1 - 1.3e-16 61.2 0.1 1.3e-16 61.2 0.1 3.3 3 1 0 3 3 3 1 SPFH domain / Band 7 family Podoplanin PF05808.11 ETS77568.1 - 0.32 11.1 8.1 0.29 11.2 6.0 2.0 1 1 0 1 1 1 0 Podoplanin LCIB_C_CA PF18599.1 ETS77568.1 - 1.1 8.6 5.2 2.1 7.6 5.2 1.5 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Cutinase PF01083.22 ETS77569.1 - 5.4e-39 134.0 4.1 6.7e-39 133.7 4.1 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 ETS77569.1 - 0.00028 20.5 0.1 0.00049 19.7 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain DUF3089 PF11288.8 ETS77569.1 - 0.00098 18.7 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) VirJ PF06057.11 ETS77569.1 - 0.0078 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.16 ETS77569.1 - 0.016 15.0 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 ETS77569.1 - 0.016 15.1 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 ETS77569.1 - 0.053 13.1 0.1 0.069 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) TIP49 PF06068.13 ETS77570.1 - 3.2e-166 552.8 0.1 3.9e-166 552.5 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 ETS77570.1 - 5.1e-25 87.4 0.3 1.4e-24 86.0 0.3 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 ETS77570.1 - 1.2e-10 41.9 0.3 6.2e-06 26.7 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ETS77570.1 - 2.3e-08 33.9 0.8 1.8e-05 24.5 0.0 3.0 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ETS77570.1 - 5.1e-05 23.6 0.2 0.24 11.7 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 ETS77570.1 - 0.00054 20.2 0.2 0.0012 19.1 0.1 1.6 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 ETS77570.1 - 0.00075 19.9 0.2 0.0057 17.0 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ETS77570.1 - 0.0014 18.7 0.2 0.043 13.8 0.1 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 ETS77570.1 - 0.0017 18.7 2.1 0.19 12.1 0.4 2.4 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 ETS77570.1 - 0.0025 17.4 0.1 0.014 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ETS77570.1 - 0.0055 17.3 0.1 0.017 15.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 ETS77570.1 - 0.019 14.4 0.1 0.7 9.2 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 ETS77570.1 - 0.019 14.7 0.1 0.045 13.5 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DnaB_C PF03796.15 ETS77570.1 - 0.042 13.2 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF2075 PF09848.9 ETS77570.1 - 0.046 13.0 0.2 0.089 12.0 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 ETS77570.1 - 0.046 13.0 0.3 0.12 11.6 0.2 1.7 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 ETS77570.1 - 0.047 13.4 0.1 2.7 7.7 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_30 PF13604.6 ETS77570.1 - 0.093 12.4 0.4 4.7 6.9 0.2 2.6 2 0 0 2 2 2 0 AAA domain HMG_box PF00505.19 ETS77571.1 - 1e-21 77.1 1.1 2e-21 76.2 1.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ETS77571.1 - 6.1e-07 29.9 0.6 1.3e-06 28.9 0.6 1.5 1 0 0 1 1 1 1 HMG-box domain Dynactin PF12455.8 ETS77572.1 - 5.8e-79 265.3 11.5 5.8e-79 265.3 11.5 4.7 5 1 0 5 5 5 1 Dynein associated protein CAP_GLY PF01302.25 ETS77572.1 - 9.6e-21 73.6 0.6 1.6e-20 72.9 0.6 1.3 1 0 0 1 1 1 1 CAP-Gly domain SRP19 PF01922.17 ETS77573.1 - 3.5e-34 117.6 0.0 5.3e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein HTH_Tnp_Tc3_2 PF01498.18 ETS77574.1 - 4.1e-16 59.0 1.1 1e-15 57.7 1.1 1.7 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 ETS77574.1 - 0.0057 16.8 0.8 0.029 14.5 0.2 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 ETS77574.1 - 0.0078 16.0 2.2 0.1 12.4 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.6 ETS77574.1 - 0.034 14.7 1.8 0.11 13.1 0.2 2.3 2 0 0 2 2 2 0 Homeodomain-like domain HTH_29 PF13551.6 ETS77574.1 - 0.068 13.2 3.7 0.07 13.2 0.3 2.4 2 1 0 2 2 2 0 Winged helix-turn helix Sigma70_r4_2 PF08281.12 ETS77574.1 - 0.087 12.5 0.0 0.63 9.8 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 DDE_3 PF13358.6 ETS77575.1 - 8e-16 58.1 0.4 1.8e-15 57.0 0.1 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Glyco_hydro_61 PF03443.14 ETS77577.1 - 0.00075 19.5 0.0 0.0017 18.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 ETS77578.1 - 3.9e-18 65.5 18.1 5.7e-18 65.0 18.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CDP-OH_P_transf PF01066.21 ETS77579.1 - 2.7e-12 47.3 0.1 9.1e-12 45.6 0.1 1.9 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase OMPdecase PF00215.24 ETS77580.1 - 9.6e-105 349.2 0.0 1.2e-104 348.9 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Zn_clus PF00172.18 ETS77581.1 - 1.6e-06 28.1 11.5 2.8e-06 27.4 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS77581.1 - 2.3e-06 26.9 0.0 7.4e-06 25.2 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain zinc_ribbon_6 PF14599.6 ETS77581.1 - 0.34 11.0 3.1 0.8 9.8 3.1 1.6 1 0 0 1 1 1 0 Zinc-ribbon zf-CCCH PF00642.24 ETS77582.1 - 0.0044 16.9 4.4 0.0044 16.9 4.4 2.9 2 1 1 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pox_A_type_inc PF04508.12 ETS77582.1 - 0.053 13.4 0.2 0.14 12.0 0.2 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Paz_1 PF18349.1 ETS77582.1 - 0.17 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 PAZ domain Torus PF16131.5 ETS77582.1 - 9 7.0 10.2 0.79 10.4 1.3 2.5 1 1 1 2 2 2 0 Torus domain Toxin_21 PF08091.11 ETS77582.1 - 9.7 6.2 13.5 3.2 7.7 3.1 2.8 2 0 0 2 2 2 0 Spider insecticidal peptide DAO PF01266.24 ETS77584.1 - 1.5e-51 176.1 0.0 2.1e-51 175.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 ETS77584.1 - 8.9e-44 148.4 0.1 1.5e-43 147.6 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 ETS77584.1 - 2.7e-07 30.0 0.4 7.6e-07 28.6 0.4 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ETS77584.1 - 9.4e-05 21.8 0.0 0.00023 20.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS77584.1 - 0.0034 16.7 0.1 0.0086 15.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ETS77584.1 - 0.0047 16.3 0.0 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS77584.1 - 0.006 16.8 0.1 0.018 15.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 ETS77584.1 - 0.01 15.7 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 ETS77584.1 - 0.093 12.0 0.6 0.46 9.7 0.2 2.0 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 ETS77584.1 - 0.094 11.9 0.0 0.89 8.7 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 ETS77584.1 - 0.095 11.4 0.2 0.15 10.7 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 ETS77584.1 - 0.12 11.5 0.0 3.2 6.8 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A MHYT PF03707.16 ETS77585.1 - 1.1e-16 60.8 30.1 3.4e-10 39.9 1.3 5.3 5 0 0 5 5 5 4 Bacterial signalling protein N terminal repeat DUF4314 PF14192.6 ETS77585.1 - 0.15 12.0 0.1 0.86 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4314) Glyco_hydro_2_C PF02836.17 ETS77586.1 - 6.4e-98 327.6 0.1 9e-98 327.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 ETS77586.1 - 3.5e-62 210.2 0.0 5.9e-62 209.4 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 ETS77586.1 - 4.3e-38 130.9 0.3 9.1e-38 129.8 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 ETS77586.1 - 1.3e-17 64.0 0.0 3.5e-17 62.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 ETS77586.1 - 4.1e-12 46.8 0.3 4e-11 43.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 ETS77586.1 - 0.017 15.7 0.0 0.074 13.6 0.0 2.0 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain Sugar_tr PF00083.24 ETS77587.1 - 3.2e-85 286.7 25.4 3.9e-85 286.4 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS77587.1 - 4.3e-38 131.2 42.7 1.2e-33 116.5 23.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS77587.1 - 0.00016 20.2 3.1 0.00016 20.2 3.1 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Bac_rhamnosid6H PF17389.2 ETS77588.1 - 2.8e-21 76.1 3.2 4.2e-19 69.0 1.9 2.1 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 ETS77588.1 - 1.5e-05 24.7 0.0 3.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 ETS77588.1 - 0.00035 19.5 0.0 0.00056 18.9 0.0 1.2 1 0 0 1 1 1 1 Trehalase Amidohydro_1 PF01979.20 ETS77590.1 - 1.9e-22 80.1 1.2 2.2e-22 79.8 1.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS77590.1 - 1.8e-09 37.6 7.8 0.00027 20.5 2.0 3.7 1 1 1 2 2 2 2 Amidohydrolase family Metallophos PF00149.28 ETS77591.1 - 2.8e-07 31.3 1.6 4.1e-07 30.7 1.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Nuc_sug_transp PF04142.15 ETS77593.1 - 8e-98 327.5 16.0 2.2e-97 326.0 16.0 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 ETS77593.1 - 3.1e-06 26.6 11.3 1.4e-05 24.5 11.3 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 ETS77593.1 - 1.1e-05 25.6 32.9 0.0025 18.0 15.5 2.5 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 ETS77593.1 - 1.8 7.8 18.6 0.58 9.4 8.2 2.7 2 1 1 3 3 3 0 Triose-phosphate Transporter family DEAD PF00270.29 ETS77594.1 - 2.4e-24 86.0 0.0 4.6e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.16 ETS77594.1 - 1.7e-17 63.5 0.0 2.5e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.31 ETS77594.1 - 2.5e-08 34.2 0.0 1e-07 32.3 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 ETS77594.1 - 1.1e-05 26.0 0.0 2.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 ETS77594.1 - 0.038 13.8 0.0 0.24 11.3 0.0 2.5 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda AAA_19 PF13245.6 ETS77594.1 - 0.041 14.2 0.0 0.6 10.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain PTS_2-RNA PF01885.16 ETS77595.1 - 1.8e-19 70.5 0.0 3.2e-19 69.7 0.0 1.5 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Lipase_GDSL_2 PF13472.6 ETS77596.1 - 1.9e-13 51.2 0.1 3.1e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS77596.1 - 2.7e-12 47.1 0.0 4.3e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 ETS77596.1 - 5.1e-05 23.5 0.0 8.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cation_efflux PF01545.21 ETS77597.1 - 6.9e-23 81.4 1.8 8.9e-23 81.1 1.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ETS77597.1 - 0.0017 18.4 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Velvet PF11754.8 ETS77598.1 - 2.5e-30 106.2 10.0 1.8e-20 73.9 0.0 3.0 1 1 2 3 3 3 2 Velvet factor 4HBT PF03061.22 ETS77599.1 - 1.7e-12 47.5 0.1 2.9e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Bactofilin PF04519.13 ETS77599.1 - 0.16 12.3 3.5 0.33 11.3 0.7 2.3 1 1 1 2 2 2 0 Polymer-forming cytoskeletal Abhydrolase_6 PF12697.7 ETS77600.1 - 7.1e-21 75.8 1.0 8.3e-21 75.6 1.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cupin_5 PF06172.11 ETS77600.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily (DUF985) AMP-binding PF00501.28 ETS77601.1 - 2.4e-70 237.2 0.0 3.7e-70 236.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 ETS77601.1 - 7.1e-63 212.9 0.0 2.8e-33 115.3 0.0 2.6 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 ETS77601.1 - 2e-17 63.3 0.8 1.2e-09 38.4 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ETS77601.1 - 0.00078 20.4 0.0 0.0029 18.5 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyr_redox_2 PF07992.14 ETS77603.1 - 1.2e-18 67.3 0.0 2.7e-18 66.2 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS77603.1 - 6.3e-07 28.8 0.5 6.1e-06 25.6 0.1 2.4 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 ETS77603.1 - 0.00047 19.4 0.2 0.0014 17.7 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 ETS77603.1 - 0.00066 19.4 1.6 0.0014 18.3 1.6 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS77603.1 - 0.0011 19.1 0.7 0.013 15.7 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ETS77603.1 - 0.0012 18.2 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ETS77603.1 - 0.0014 17.4 0.1 0.0078 15.0 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 ETS77603.1 - 0.0052 16.1 0.3 0.041 13.1 0.1 2.3 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS77603.1 - 0.012 14.7 0.4 0.064 12.3 0.2 2.0 1 1 1 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 ETS77603.1 - 0.02 14.1 0.1 0.036 13.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.6 ETS77603.1 - 0.098 11.8 0.0 6.7 5.7 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 ETS77603.1 - 0.1 11.9 0.6 0.2 11.0 0.6 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ETS77603.1 - 0.13 11.0 0.3 0.19 10.6 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 ETS77603.1 - 0.22 11.5 0.6 22 5.0 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ETS77604.1 - 1.3e-16 60.7 0.2 3.5e-08 33.0 0.0 2.9 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS77604.1 - 1.5e-05 24.3 0.2 4.2e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 ETS77604.1 - 1.9e-05 24.8 0.0 1.9e-05 24.8 0.0 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS77604.1 - 2.4e-05 24.1 2.1 6.6e-05 22.7 0.7 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS77604.1 - 8.4e-05 22.0 0.3 0.18 11.0 0.1 2.9 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS77604.1 - 0.00037 20.5 1.1 0.29 11.1 0.3 2.3 1 1 1 2 2 2 2 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 ETS77604.1 - 0.0016 17.8 0.3 0.0059 15.9 0.1 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 ETS77604.1 - 0.0021 17.2 3.5 0.16 11.0 1.2 2.3 1 1 1 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 ETS77604.1 - 0.0044 16.3 0.0 0.019 14.2 0.1 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 ETS77604.1 - 0.0057 15.4 0.8 0.017 13.8 0.3 1.9 1 1 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 ETS77604.1 - 0.014 14.8 0.8 0.03 13.7 0.8 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ETS77604.1 - 0.037 13.3 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.16 ETS77605.1 - 9.9e-42 143.1 55.9 3.5e-41 141.3 51.7 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS77605.1 - 3.9e-18 65.2 13.3 6.1e-18 64.6 13.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS77605.1 - 2.4e-11 43.2 11.6 2.4e-11 43.2 11.6 3.1 1 1 2 3 3 3 1 Sugar (and other) transporter Peptidase_M19 PF01244.21 ETS77606.1 - 8.5e-104 347.1 0.0 9.8e-104 346.9 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Methyltransf_2 PF00891.18 ETS77607.1 - 2.7e-11 43.2 0.1 3.9e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 ETS77607.1 - 0.0042 17.8 0.0 0.01 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain HTH_Tnp_ISL3 PF13542.6 ETS77607.1 - 0.022 14.2 0.1 0.072 12.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Zn_clus PF00172.18 ETS77608.1 - 0.00016 21.7 13.0 0.00029 20.9 13.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.21 ETS77609.1 - 3.2e-34 118.7 0.0 3.8e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ETS77609.1 - 0.0053 16.1 0.0 0.0087 15.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Rax2 PF12768.7 ETS77610.1 - 0.13 11.7 0.5 1.1 8.6 0.0 2.5 3 0 0 3 3 3 0 Cortical protein marker for cell polarity Methyltransf_25 PF13649.6 ETS77613.1 - 9.1e-12 45.5 0.0 2e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS77613.1 - 2.5e-10 40.8 0.0 4.3e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS77613.1 - 5.4e-05 23.9 0.0 9.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS77613.1 - 0.00023 21.0 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS77613.1 - 0.00065 19.1 0.0 0.00097 18.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ETS77613.1 - 0.0032 17.3 0.0 0.0059 16.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS77613.1 - 0.02 14.5 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_29 PF03141.16 ETS77613.1 - 0.17 10.4 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.6 ETS77614.1 - 1.7e-10 41.0 0.0 2.4e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS77614.1 - 5.4e-07 29.5 0.0 1.6e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS77614.1 - 3e-06 27.8 0.0 5.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS77614.1 - 1.1e-05 26.1 0.0 2.9e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS77614.1 - 0.0025 18.5 0.0 0.0069 17.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS77615.1 - 1.5e-15 57.7 0.0 2.8e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS77615.1 - 7.9e-14 52.1 0.0 1.4e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS77615.1 - 4.3e-11 43.4 0.0 8.6e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS77615.1 - 8.2e-10 38.4 0.0 1.3e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ETS77615.1 - 1.2e-09 38.1 0.0 1.8e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS77615.1 - 2e-08 34.3 0.0 2.9e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS77615.1 - 0.00034 20.2 0.0 0.00054 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ETS77615.1 - 0.05 13.0 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) p450 PF00067.22 ETS77616.1 - 1e-39 136.6 0.0 1.3e-39 136.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GST_C_3 PF14497.6 ETS77617.1 - 2.5e-06 27.6 0.0 8.2e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ETS77617.1 - 2.9e-06 27.4 0.1 6.1e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ETS77617.1 - 3.9e-05 23.6 0.1 3.9e-05 23.6 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ETS77617.1 - 0.0001 22.5 0.1 0.00019 21.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ETS77617.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ETS77617.1 - 0.015 15.7 0.1 0.031 14.6 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Methyltransf_2 PF00891.18 ETS77618.1 - 4.4e-35 120.9 0.0 9.9e-35 119.7 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 ETS77618.1 - 2.2e-08 34.0 0.0 3.7e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 ETS77618.1 - 0.0075 16.3 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain HTH_15 PF12324.8 ETS77618.1 - 0.011 15.7 0.0 0.32 11.0 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase DUF4743 PF15916.5 ETS77618.1 - 0.038 14.0 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) HTH_Crp_2 PF13545.6 ETS77618.1 - 0.14 12.1 0.1 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain p450 PF00067.22 ETS77619.1 - 8.2e-05 21.5 0.0 0.0011 17.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 MBOAT_2 PF13813.6 ETS77620.1 - 7.7e-17 61.3 3.3 7.7e-17 61.3 3.3 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Abhydrolase_3 PF07859.13 ETS77624.1 - 2.1e-48 165.0 0.0 2.8e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS77624.1 - 1.4e-13 50.6 0.0 7.2e-13 48.2 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 ETS77624.1 - 0.00011 22.9 0.2 0.00018 22.2 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 ETS77624.1 - 0.21 10.4 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase COesterase PF00135.28 ETS77625.1 - 4.8e-96 322.6 0.1 6.6e-96 322.2 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS77625.1 - 8.8e-05 22.4 0.1 0.013 15.3 0.0 2.5 2 1 1 3 3 3 2 alpha/beta hydrolase fold GMC_oxred_N PF00732.19 ETS77626.1 - 1.2e-49 169.3 0.0 1.6e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS77626.1 - 1.8e-29 103.1 0.0 2.7e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ETS77626.1 - 0.0011 18.1 0.2 0.0022 17.1 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ETS77626.1 - 0.0017 17.7 0.2 0.28 10.4 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS77626.1 - 0.015 14.4 0.3 2 7.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ETS77626.1 - 0.037 13.1 0.0 0.38 9.8 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Aldo_ket_red PF00248.21 ETS77627.1 - 5.9e-67 225.9 0.0 6.7e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1772 PF08592.11 ETS77628.1 - 5e-20 72.2 0.0 6.2e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) NACHT_N PF17100.5 ETS77629.1 - 3.5e-57 193.8 1.0 6e-57 193.0 0.0 1.9 3 0 0 3 3 3 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 ETS77629.1 - 1.7e-38 131.0 0.0 8.9e-15 55.1 0.0 4.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS77629.1 - 3.2e-29 100.9 0.0 8e-11 42.2 0.0 5.3 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 ETS77629.1 - 2.5e-26 90.9 0.0 0.0014 18.9 0.0 6.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 ETS77629.1 - 7.2e-23 78.2 0.0 0.0044 17.4 0.0 6.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 ETS77629.1 - 1.3e-19 70.0 0.0 3e-05 24.2 0.1 4.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) AAA_16 PF13191.6 ETS77629.1 - 2.2e-06 28.2 0.1 1e-05 26.0 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 ETS77629.1 - 2e-05 24.6 0.1 7.5e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 ETS77629.1 - 0.00051 20.5 0.1 0.016 15.6 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS77629.1 - 0.0029 17.9 0.0 0.01 16.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ETS77629.1 - 0.062 13.3 0.0 0.26 11.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain Bac_luciferase PF00296.20 ETS77631.1 - 4.1e-63 213.7 0.3 5.1e-63 213.4 0.3 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase B12-binding PF02310.19 ETS77631.1 - 0.16 12.0 0.0 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 B12 binding domain Peptidase_M24 PF00557.24 ETS77632.1 - 1.7e-50 171.6 0.0 2.5e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ETS77632.1 - 8.5e-19 67.5 0.0 1.9e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HNH_4 PF13395.6 ETS77632.1 - 0.14 12.1 0.0 0.41 10.6 0.0 1.8 1 0 0 1 1 1 0 HNH endonuclease ADH_zinc_N_2 PF13602.6 ETS77633.1 - 1.7e-14 55.0 0.0 8.8e-14 52.7 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ETS77633.1 - 3.5e-10 39.9 0.0 6.3e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS77633.1 - 0.0074 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GDC-P PF02347.16 ETS77633.1 - 0.16 10.8 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Dabb PF07876.12 ETS77634.1 - 1.3e-14 54.6 0.0 1.6e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain MFS_1 PF07690.16 ETS77635.1 - 5e-41 140.8 50.0 1.4e-40 139.4 46.5 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily SGL PF08450.12 ETS77636.1 - 8.6e-23 81.2 0.3 3.5e-21 75.9 0.3 2.2 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 ETS77636.1 - 1.6e-06 28.2 0.0 4.7e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.20 ETS77636.1 - 6.4e-05 23.1 0.0 0.0002 21.5 0.0 1.9 2 0 0 2 2 2 1 Arylesterase NHL PF01436.21 ETS77636.1 - 0.046 13.8 1.7 19 5.5 0.1 3.4 3 0 0 3 3 3 0 NHL repeat PD40 PF07676.12 ETS77636.1 - 0.078 12.9 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 ETS77636.1 - 2.2 8.9 6.6 6.2 7.4 0.7 3.5 3 0 0 3 3 3 0 PQQ-like domain TauD PF02668.16 ETS77637.1 - 1.1e-47 163.1 0.2 1.3e-47 162.8 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 ETS77638.1 - 3e-38 131.7 30.2 3e-38 131.7 30.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS77638.1 - 7.5e-09 34.9 3.3 7.5e-09 34.9 3.3 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 ETS77638.1 - 0.0089 14.4 1.8 0.016 13.5 0.3 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family FTR1 PF03239.14 ETS77638.1 - 0.13 11.4 6.8 0.98 8.5 0.1 2.3 1 1 1 2 2 2 0 Iron permease FTR1 family TauD PF02668.16 ETS77639.1 - 6.5e-43 147.5 0.0 8.6e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MmgE_PrpD PF03972.14 ETS77640.1 - 1.7e-107 359.7 0.2 2e-107 359.5 0.2 1.0 1 0 0 1 1 1 1 MmgE/PrpD family TSCPD PF12637.7 ETS77640.1 - 0.043 14.1 0.0 1.5 9.1 0.0 2.9 2 0 0 2 2 2 0 TSCPD domain DUF1729 PF08354.10 ETS77641.1 - 5.2e-140 466.4 0.0 7.3e-140 465.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 ETS77641.1 - 7.6e-63 212.9 0.0 3.7e-62 210.7 0.0 2.1 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.19 ETS77641.1 - 5.5e-27 93.8 0.0 1.3e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 ETS77641.1 - 7.1e-27 94.7 0.0 1.4e-26 93.7 0.0 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_meander PF17951.1 ETS77641.1 - 2.6e-15 56.5 0.0 5.5e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydrat_N PF13452.6 ETS77641.1 - 2.7e-05 24.3 0.0 0.0051 16.9 0.0 2.7 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase FAS_N PF17828.1 ETS77641.1 - 0.0011 18.9 0.7 0.0028 17.7 0.7 1.7 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta HisK_sensor PF18698.1 ETS77641.1 - 0.12 12.8 0.2 0.25 11.7 0.2 1.5 1 0 0 1 1 1 0 Histidine kinase sensor domain TubC_N PF18563.1 ETS77641.1 - 0.14 12.1 0.1 0.41 10.7 0.1 1.8 1 0 0 1 1 1 0 TubC N-terminal docking domain MmgE_PrpD PF03972.14 ETS77642.1 - 1.3e-110 370.0 0.1 1.6e-110 369.7 0.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Citrate_synt PF00285.21 ETS77643.1 - 2e-102 343.0 0.0 2.3e-102 342.7 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Fas_alpha_ACP PF18325.1 ETS77644.1 - 9.1e-55 185.4 0.0 1.6e-54 184.7 0.0 1.4 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 ETS77644.1 - 1.9e-38 132.2 0.1 3.4e-38 131.3 0.1 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 ETS77644.1 - 1.5e-20 73.9 0.3 2.8e-20 73.0 0.3 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ETS77644.1 - 1.6e-16 60.4 0.1 1.2e-15 57.6 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 ETS77644.1 - 2.6e-06 27.0 0.0 9.3e-06 25.2 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS77644.1 - 4.4e-06 26.7 0.6 1.3e-05 25.2 0.1 2.0 2 0 0 2 2 2 1 KR domain CwsA PF10814.8 ETS77644.1 - 0.011 15.9 0.1 10 6.3 0.0 4.0 2 1 1 3 3 3 0 Cell wall synthesis protein CwsA Thiolase_N PF00108.23 ETS77644.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain ASL_C PF08328.11 ETS77644.1 - 0.15 12.2 0.1 0.41 10.8 0.1 1.7 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal Zn_clus PF00172.18 ETS77645.1 - 1.2e-11 44.5 12.2 2.5e-11 43.5 12.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS77645.1 - 5e-08 32.3 0.0 8.3e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MCM_lid PF17855.1 ETS77645.1 - 0.17 12.3 0.2 30 5.1 0.1 2.4 2 0 0 2 2 2 0 MCM AAA-lid domain DNA_pol_alpha_N PF12254.8 ETS77647.1 - 0.016 15.3 0.5 0.023 14.7 0.5 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Sugar_tr PF00083.24 ETS77648.1 - 3.6e-108 362.3 25.3 4.4e-108 362.1 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS77648.1 - 5.6e-25 88.0 31.1 6.7e-19 68.0 7.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP-sulfurylase PF01747.17 ETS77650.1 - 9.6e-88 293.2 0.0 1.3e-87 292.7 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 ETS77650.1 - 7.8e-57 191.6 0.0 1.2e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 ETS77650.1 - 4.1e-55 185.8 0.0 6.7e-55 185.1 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain Dioxygenase_C PF00775.21 ETS77651.1 - 1.5e-44 151.6 0.0 2e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 ETS77651.1 - 8e-31 105.7 0.0 1.9e-30 104.5 0.0 1.7 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 ETS77651.1 - 0.066 13.5 0.0 0.21 11.9 0.0 1.8 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Fungal_trans PF04082.18 ETS77652.1 - 4.2e-24 85.0 0.0 6.5e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Polyketide_cyc2 PF10604.9 ETS77653.1 - 0.0064 16.8 4.5 0.053 13.8 2.1 2.4 1 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ETS77653.1 - 0.027 14.7 0.1 0.058 13.6 0.1 1.6 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Melibiase_2 PF16499.5 ETS77654.1 - 2.3e-60 204.2 14.2 1.7e-59 201.4 14.2 2.2 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 ETS77654.1 - 7.4e-08 31.7 0.4 1.6e-07 30.7 0.1 1.6 2 0 0 2 2 2 1 Melibiase Melibiase_C PF17801.1 ETS77654.1 - 4.8e-06 26.6 1.0 0.00075 19.5 0.2 2.8 2 0 0 2 2 2 2 Alpha galactosidase C-terminal beta sandwich domain MFS_1 PF07690.16 ETS77655.1 - 2.7e-30 105.5 43.7 6.2e-30 104.3 43.7 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS77655.1 - 6.1e-13 48.1 20.3 8.6e-13 47.6 20.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ketoacyl-synt PF00109.26 ETS77656.1 - 4.9e-75 252.4 0.0 8.3e-75 251.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ETS77656.1 - 7.5e-51 172.6 0.4 2e-50 171.2 0.0 2.0 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 ETS77656.1 - 1.4e-44 153.0 0.1 2.5e-44 152.1 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 ETS77656.1 - 2.3e-42 145.3 0.0 4e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 ETS77656.1 - 4.7e-37 126.6 0.6 1.5e-36 125.0 0.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ETS77656.1 - 8.9e-18 64.8 0.0 3e-17 63.1 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 ETS77656.1 - 7.3e-15 54.9 0.2 2.7e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS77656.1 - 2.6e-10 40.2 0.0 5.8e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 ETS77656.1 - 2.8e-05 24.1 0.7 0.00016 21.6 0.1 2.6 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS77656.1 - 0.00085 19.2 0.0 0.006 16.5 0.1 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 ETS77656.1 - 0.0028 17.0 0.1 0.0067 15.8 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ThiF PF00899.21 ETS77656.1 - 0.014 14.8 0.1 0.029 13.7 0.1 1.5 1 0 0 1 1 1 0 ThiF family PP-binding PF00550.25 ETS77656.1 - 0.043 14.2 0.1 0.15 12.5 0.0 2.1 2 0 0 2 2 1 0 Phosphopantetheine attachment site Asp PF00026.23 ETS77657.1 - 9.8e-66 222.3 3.1 4.7e-65 220.1 3.1 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS77657.1 - 2.7e-09 37.5 4.4 1.6e-06 28.5 0.1 3.3 3 1 1 4 4 4 2 Xylanase inhibitor N-terminal Sporozoite_P67 PF05642.11 ETS77657.1 - 4 5.4 8.2 5.6 4.9 8.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen OPT PF03169.15 ETS77658.1 - 2.4e-187 624.4 48.4 2.8e-187 624.1 48.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MoaE PF02391.17 ETS77659.1 - 1.4e-36 125.2 0.0 1.7e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 MoaE protein G-patch PF01585.23 ETS77660.1 - 4.1e-09 36.2 3.2 5.2e-09 35.8 1.7 1.9 2 0 0 2 2 2 1 G-patch domain RRM_1 PF00076.22 ETS77660.1 - 8e-08 32.0 0.3 0.0091 15.8 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 ETS77660.1 - 2.6e-07 29.8 4.2 4.3e-07 29.1 4.2 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 ETS77660.1 - 0.00013 22.0 1.7 0.00013 22.0 1.7 2.7 3 0 0 3 3 3 1 G-patch domain zf-C2H2_11 PF16622.5 ETS77660.1 - 0.0037 17.0 2.2 0.0037 17.0 2.2 2.3 3 0 0 3 3 3 1 zinc-finger C2H2-type RED_N PF07808.13 ETS77660.1 - 0.0098 15.5 1.3 0.0098 15.5 1.3 2.6 2 0 0 2 2 2 1 RED-like protein N-terminal region LIM_bind PF01803.16 ETS77660.1 - 0.12 11.8 1.6 2.8 7.4 0.0 2.8 3 0 0 3 3 3 0 LIM-domain binding protein ISN1 PF06437.11 ETS77662.1 - 2.6e-186 619.5 0.0 2.9e-186 619.3 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Rootletin PF15035.6 ETS77663.1 - 0.45 10.5 14.6 1 9.3 14.6 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CorA PF01544.18 ETS77663.1 - 3.7 6.8 6.6 1.7 7.9 3.8 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Apolipoprotein PF01442.18 ETS77664.1 - 0.025 14.5 3.2 0.32 10.8 0.1 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4549 PF15082.6 ETS77664.1 - 0.061 13.1 0.4 0.13 12.0 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) Baculo_PEP_C PF04513.12 ETS77664.1 - 3.4 7.7 6.0 3.3 7.7 1.3 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ubiquitin PF00240.23 ETS77665.1 - 7.3e-08 32.1 0.0 4.6e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 ETS77665.1 - 0.078 12.8 0.0 0.078 12.8 0.0 2.1 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like NinD PF17466.2 ETS77665.1 - 0.33 11.1 2.8 1 9.5 2.8 1.9 1 0 0 1 1 1 0 Family of unknown function YL1 PF05764.13 ETS77665.1 - 5.8 7.0 6.4 11 6.0 6.4 1.4 1 0 0 1 1 1 0 YL1 nuclear protein DUF2235 PF09994.9 ETS77666.1 - 1.3e-29 103.5 0.0 1.6e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) IBN_N PF03810.19 ETS77667.1 - 5.9e-14 51.7 0.3 8.6e-12 44.8 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 ETS77667.1 - 7.5e-08 31.6 0.1 2.5e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Cse1 Xpo1 PF08389.12 ETS77667.1 - 0.0037 17.3 1.2 0.039 14.0 0.0 3.4 5 0 0 5 5 5 1 Exportin 1-like protein CAS_CSE1 PF03378.15 ETS77667.1 - 0.0092 14.5 0.0 0.027 13.0 0.0 1.7 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cnd1 PF12717.7 ETS77667.1 - 0.027 14.5 0.2 0.23 11.5 0.1 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ETS77667.1 - 0.17 12.5 3.5 3.8 8.2 0.1 3.9 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 ETS77667.1 - 0.17 12.3 6.7 1 9.8 0.3 3.7 4 0 0 4 4 4 0 HEAT repeats HEAT PF02985.22 ETS77667.1 - 0.26 11.6 1.4 1.4 9.4 0.1 3.1 3 0 0 3 3 3 0 HEAT repeat IMS PF00817.20 ETS77669.1 - 8.5e-42 142.7 0.0 1.4e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 ETS77669.1 - 2.3e-13 50.9 0.0 1.2e-12 48.5 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 ETS77669.1 - 7.7e-11 41.4 1.3 1.6e-10 40.4 1.3 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 ETS77669.1 - 0.00098 19.3 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif zf_C2H2_ZHX PF18387.1 ETS77669.1 - 0.069 12.8 0.2 0.19 11.4 0.2 1.7 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 ETS77669.1 - 0.089 13.2 1.0 0.25 11.8 1.0 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DHHC PF01529.20 ETS77670.1 - 5.7e-26 91.2 1.9 5.7e-26 91.2 1.9 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Cupin_1 PF00190.22 ETS77671.1 - 3.8e-09 36.3 0.0 5.7e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 ETS77671.1 - 6.6e-09 35.4 0.3 4.8e-05 23.0 0.0 2.4 2 1 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 ETS77671.1 - 0.11 12.2 0.3 0.91 9.3 0.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_6 PF12852.7 ETS77671.1 - 0.14 11.8 0.4 1.5 8.5 0.4 2.1 1 1 0 1 1 1 0 Cupin Pro_dh PF01619.18 ETS77672.1 - 1.4e-60 205.4 0.0 1.6e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase NUDIX PF00293.28 ETS77673.1 - 4.5e-07 30.0 0.1 6.9e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain HET PF06985.11 ETS77674.1 - 1e-22 81.1 0.3 2.4e-22 79.8 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AA_permease PF00324.21 ETS77675.1 - 2.9e-104 349.3 39.5 3.6e-104 349.0 39.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS77675.1 - 4.7e-23 81.7 41.4 5.9e-23 81.4 41.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4131 PF13567.6 ETS77675.1 - 0.15 11.7 1.9 0.48 10.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) FixQ PF05545.11 ETS77675.1 - 0.68 9.9 7.3 0.48 10.4 3.0 2.9 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ P5CR_dimer PF14748.6 ETS77676.1 - 4.7e-31 107.1 0.8 9.4e-31 106.1 0.8 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 ETS77676.1 - 1.4e-13 51.2 0.2 3.4e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 ETS77676.1 - 0.058 13.0 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 ETS77676.1 - 0.079 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Aldedh PF00171.22 ETS77677.1 - 3.7e-93 312.5 0.0 4.7e-93 312.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DAO PF01266.24 ETS77679.1 - 4.4e-34 118.6 0.1 5.1e-34 118.4 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS77679.1 - 2.8e-07 30.6 0.0 8.5e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS77679.1 - 0.00017 21.0 0.0 0.00061 19.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS77679.1 - 0.0002 20.7 0.0 0.012 14.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS77679.1 - 0.0012 18.0 0.2 0.0042 16.2 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 ETS77679.1 - 0.003 17.8 0.0 0.0063 16.8 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_3 PF01494.19 ETS77679.1 - 0.0058 15.9 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 ETS77679.1 - 0.0096 15.9 0.0 0.072 13.1 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.22 ETS77679.1 - 0.011 14.8 0.1 3 6.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 ETS77679.1 - 0.016 15.7 0.3 0.13 12.9 0.0 2.5 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 ETS77679.1 - 0.03 13.7 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 ETS77679.1 - 0.032 14.3 0.0 0.081 13.0 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 ETS77679.1 - 0.052 12.2 0.1 0.27 9.9 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 ETS77679.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 ETS77679.1 - 0.082 12.2 0.0 0.51 9.6 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Glu_dehyd_C PF16912.5 ETS77679.1 - 0.11 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 ETS77679.1 - 0.16 12.4 0.1 0.31 11.5 0.0 1.6 2 0 0 2 2 1 0 Putative NAD(P)-binding ApbA PF02558.16 ETS77679.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GMC_oxred_N PF00732.19 ETS77679.1 - 0.18 11.2 0.2 2.9 7.2 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Fungal_trans PF04082.18 ETS77680.1 - 1.6e-15 56.9 0.4 3e-15 56.0 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS77680.1 - 4.3e-07 30.0 12.6 8.8e-07 28.9 12.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_2 PF03446.15 ETS77681.1 - 1.6e-27 96.6 0.4 2.7e-27 95.9 0.4 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ETS77681.1 - 6e-08 33.0 0.2 1.8e-07 31.4 0.2 1.8 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ETS77681.1 - 0.003 18.1 0.1 0.0086 16.6 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 ETS77681.1 - 0.0072 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase RraA-like PF03737.15 ETS77682.1 - 5.1e-33 114.4 0.0 6.5e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA Ku_PK_bind PF08785.11 ETS77683.1 - 0.066 13.4 0.3 0.17 12.0 0.3 1.6 1 0 0 1 1 1 0 Ku C terminal domain like Dabb PF07876.12 ETS77684.1 - 2.4e-11 44.1 0.0 3.1e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ldt_C PF17969.1 ETS77684.1 - 0.094 13.5 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 L,D-transpeptidase C-terminal domain PAF-AH_p_II PF03403.13 ETS77685.1 - 6.3e-38 130.3 0.0 7e-29 100.5 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ETS77685.1 - 8.6e-08 31.4 0.1 5.7e-07 28.7 0.1 2.0 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 ETS77685.1 - 2e-07 31.8 0.2 3.3e-07 31.2 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS77685.1 - 2e-05 24.0 0.9 0.017 14.4 0.1 2.6 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 ETS77685.1 - 0.0046 16.0 0.0 0.0094 15.0 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_3 PF07859.13 ETS77685.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 ETS77685.1 - 0.084 12.5 0.0 0.27 10.9 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold HTH_Tnp_Tc5 PF03221.16 ETS77686.1 - 6e-12 45.4 0.0 8.8e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_30 PF13556.6 ETS77686.1 - 0.00093 19.0 0.1 0.0017 18.1 0.1 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain HTH_psq PF05225.16 ETS77686.1 - 0.0025 17.5 0.1 0.0046 16.7 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_ISL3 PF13542.6 ETS77686.1 - 0.018 14.5 0.1 0.033 13.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.6 ETS77686.1 - 0.021 14.9 0.2 0.062 13.4 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_AsnC-type PF13404.6 ETS77686.1 - 0.026 14.3 0.3 0.042 13.7 0.3 1.3 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_23 PF13384.6 ETS77686.1 - 0.032 14.0 0.2 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_1 PF01527.20 ETS77686.1 - 0.036 14.4 0.1 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 Transposase HTH_8 PF02954.19 ETS77686.1 - 0.038 13.8 0.3 0.07 12.9 0.3 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family DUF2089 PF09862.9 ETS77686.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) MFS_1 PF07690.16 ETS77687.1 - 1.6e-20 73.3 77.0 6.7e-16 58.1 41.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_1 PF00232.18 ETS77688.1 - 2.5e-70 237.1 0.7 1.1e-69 235.0 0.7 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 AA_permease_2 PF13520.6 ETS77689.1 - 2.2e-52 178.4 44.9 2.6e-52 178.1 44.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS77689.1 - 2.6e-16 59.3 34.3 3.7e-16 58.8 34.3 1.1 1 0 0 1 1 1 1 Amino acid permease SHR3_chaperone PF08229.11 ETS77689.1 - 0.032 13.2 0.3 0.094 11.7 0.3 1.8 1 0 0 1 1 1 0 ER membrane protein SH3 Hexapep PF00132.24 ETS77690.1 - 7.8e-13 47.6 7.8 3.7e-10 39.1 2.2 3.4 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 ETS77690.1 - 8.1e-13 48.4 0.0 1.2e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 ETS77690.1 - 9.6e-10 38.0 8.2 1.7e-07 30.9 1.6 3.3 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase ACT_6 PF13740.6 ETS77690.1 - 0.12 12.4 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 ACT domain Ribonuc_L-PSP PF01042.21 ETS77691.1 - 4.2e-11 42.9 0.0 5.2e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP motB PF17613.2 ETS77691.1 - 0.094 12.6 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Modifier of transcription Beta-lactamase PF00144.24 ETS77692.1 - 3.4e-41 141.6 0.0 6.7e-41 140.6 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase Abhydrolase_3 PF07859.13 ETS77693.1 - 8.6e-17 61.7 0.0 5.3e-16 59.1 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS77693.1 - 2.5e-09 36.9 0.0 0.00097 18.7 0.0 2.8 2 1 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ETS77693.1 - 4.2e-07 29.5 0.1 5e-06 25.9 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 COesterase PF00135.28 ETS77693.1 - 0.00044 19.2 0.0 0.0086 15.0 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase2 PF12740.7 ETS77693.1 - 0.0015 17.5 0.0 0.0022 17.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 ETS77693.1 - 0.027 14.1 0.1 1.7 8.2 0.1 2.3 2 1 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 ETS77693.1 - 0.1 12.1 0.0 15 5.1 0.0 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) LIDHydrolase PF10230.9 ETS77693.1 - 0.11 12.1 0.0 0.7 9.4 0.0 2.1 3 0 0 3 3 3 0 Lipid-droplet associated hydrolase DAO PF01266.24 ETS77694.1 - 2.9e-27 96.2 0.6 3.3e-27 96.0 0.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS77694.1 - 0.00044 20.8 0.7 0.00091 19.7 0.7 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS77694.1 - 0.00071 18.9 0.6 0.0065 15.7 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS77694.1 - 0.036 14.3 0.2 0.091 13.0 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS77694.1 - 0.083 12.9 0.3 0.57 10.2 0.1 2.1 1 1 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 ETS77694.1 - 0.1 12.5 0.2 0.2 11.6 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ETS77694.1 - 0.16 12.0 0.1 8.5 6.3 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Aminotran_4 PF01063.19 ETS77695.1 - 3.2e-42 144.9 0.0 3.9e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV NMT1_3 PF16868.5 ETS77695.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family Fungal_trans_2 PF11951.8 ETS77696.1 - 6.8e-25 87.7 2.2 1.1e-24 87.0 2.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 ETS77697.1 - 3.9e-54 183.7 1.1 4.5e-54 183.5 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS77697.1 - 3.2e-44 150.7 1.9 4.2e-44 150.4 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS77697.1 - 1.6e-18 67.3 0.4 2.3e-18 66.8 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS77697.1 - 0.00025 20.6 0.3 0.0013 18.3 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 ETS77697.1 - 0.0012 18.2 0.1 0.0025 17.1 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Amino_oxidase PF01593.24 ETS77698.1 - 1.9e-44 152.8 0.1 2.7e-44 152.2 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 ETS77698.1 - 1.7e-12 47.6 0.0 1.2e-06 28.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS77698.1 - 3.9e-12 46.2 1.0 8e-12 45.2 0.5 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS77698.1 - 2.7e-07 30.1 0.1 1.7e-06 27.4 0.0 2.2 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 ETS77698.1 - 5.4e-07 29.3 0.1 1.2e-06 28.2 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS77698.1 - 1e-06 28.2 0.4 2.4e-06 27.0 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS77698.1 - 3.9e-05 22.9 0.1 6.2e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 ETS77698.1 - 4.7e-05 22.7 0.0 8.3e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 ETS77698.1 - 7.4e-05 21.6 0.0 0.00014 20.7 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 ETS77698.1 - 7.9e-05 23.1 0.0 0.0003 21.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS77698.1 - 0.0042 16.4 0.0 0.12 11.6 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 ETS77698.1 - 0.005 15.9 0.0 0.0091 15.1 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 ETS77698.1 - 0.028 13.7 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 ETS77698.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_3_C PF01915.22 ETS77700.1 - 1.8e-34 119.5 0.0 7.1e-31 107.8 0.0 2.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS77700.1 - 4.7e-31 108.3 0.0 7.7e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS77700.1 - 2.2e-15 56.5 0.0 4e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain CENP-R PF06729.12 ETS77700.1 - 0.11 12.4 0.2 0.19 11.7 0.2 1.3 1 0 0 1 1 1 0 Kinetochore component, CENP-R HATPase_c PF02518.26 ETS77702.1 - 2.8e-24 85.8 0.0 7.3e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ETS77702.1 - 9.5e-22 77.3 0.6 3.7e-21 75.4 0.4 2.2 2 0 0 2 2 2 1 Response regulator receiver domain PAS_9 PF13426.7 ETS77702.1 - 3.1e-16 59.5 0.0 0.0001 22.5 0.0 3.8 3 0 0 3 3 3 3 PAS domain PAS PF00989.25 ETS77702.1 - 2.4e-12 46.9 0.0 0.00026 20.9 0.0 3.9 3 0 0 3 3 3 3 PAS fold PAS_8 PF13188.7 ETS77702.1 - 1.3e-11 44.3 0.0 0.015 15.3 0.0 3.7 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 ETS77702.1 - 2.8e-11 43.5 0.0 4.9e-05 23.5 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 ETS77702.1 - 3e-10 40.3 0.0 0.04 14.2 0.0 5.0 5 0 0 5 5 5 3 PAS fold HisKA PF00512.25 ETS77702.1 - 1.4e-08 34.6 0.3 1.7e-07 31.2 0.3 2.7 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 ETS77702.1 - 0.039 14.2 0.0 0.23 11.8 0.0 2.3 3 0 0 3 3 3 0 GAF domain SprT-like PF10263.9 ETS77703.1 - 0.00014 21.7 0.0 0.00036 20.4 0.0 1.6 2 0 0 2 2 2 1 SprT-like family Peptidase_M50B PF13398.6 ETS77703.1 - 0.0028 17.3 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase M50B-like TRP PF06011.12 ETS77704.1 - 1.7e-117 392.7 15.3 2.2e-117 392.4 15.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 ETS77704.1 - 4.2e-37 127.6 0.1 7.2e-37 126.8 0.1 1.4 1 0 0 1 1 1 1 ML-like domain EI24 PF07264.11 ETS77706.1 - 3.5e-16 60.0 7.1 6.9e-16 59.0 7.1 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) PMP1_2 PF08114.11 ETS77706.1 - 0.8 9.5 3.3 19 5.1 0.6 2.6 2 0 0 2 2 2 0 ATPase proteolipid family Cutinase PF01083.22 ETS77707.1 - 6.6e-41 140.2 2.1 7.7e-41 140.0 2.1 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 ETS77707.1 - 0.00072 19.2 0.4 0.00095 18.8 0.4 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 ETS77707.1 - 0.025 14.4 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF3089 PF11288.8 ETS77707.1 - 0.044 13.3 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Herpes_LMP1 PF05297.11 ETS77708.1 - 7.2 5.7 6.1 12 5.0 6.1 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) ABM PF03992.16 ETS77709.1 - 0.00049 20.2 0.5 0.00071 19.6 0.5 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase AMP-binding PF00501.28 ETS77710.1 - 5.8e-12 44.9 0.0 7.4e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cytochrom_C_2 PF01322.20 ETS77710.1 - 0.18 12.7 0.1 1.3 9.9 0.0 2.4 3 0 0 3 3 3 0 Cytochrome C' Chordopox_A33R PF05966.12 ETS77710.1 - 0.2 10.9 0.1 0.58 9.4 0.0 1.7 2 0 0 2 2 2 0 Chordopoxvirus A33R protein Ank_2 PF12796.7 ETS77711.1 - 0.00045 20.7 0.0 0.13 12.8 0.0 3.4 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS77711.1 - 0.0019 18.7 0.1 6.4 7.5 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeats (many copies) F-box PF00646.33 ETS77711.1 - 0.013 15.3 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 F-box domain Ank_3 PF13606.6 ETS77711.1 - 0.026 15.0 0.1 5 8.0 0.0 4.0 4 0 0 4 4 4 0 Ankyrin repeat Fungal_trans_2 PF11951.8 ETS77712.1 - 8.9e-06 24.8 0.3 0.0038 16.1 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain adh_short PF00106.25 ETS77713.1 - 2.4e-15 56.5 0.0 1.8e-12 47.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS77713.1 - 1e-09 38.3 0.0 3.5e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS77713.1 - 4e-05 23.6 0.0 7.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 ETS77713.1 - 0.057 13.5 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_4 PF01565.23 ETS77714.1 - 1.7e-23 82.9 0.4 3.2e-23 82.0 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain zf-C2H2_4 PF13894.6 ETS77715.1 - 0.00059 20.4 17.5 0.036 14.9 2.0 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ETS77715.1 - 0.0084 16.4 1.5 0.0084 16.4 1.5 3.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ETS77715.1 - 0.017 15.5 0.6 0.017 15.5 0.6 4.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 ETS77715.1 - 0.037 14.5 1.4 0.037 14.5 1.4 4.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-LYAR PF08790.11 ETS77715.1 - 0.041 13.8 4.4 3.3 7.7 0.2 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_2 PF13465.6 ETS77715.1 - 0.096 13.2 6.3 2 9.0 0.6 2.8 2 0 0 2 2 2 0 Zinc-finger double domain C1_4 PF07975.12 ETS77715.1 - 4.9 7.5 6.0 20 5.5 6.0 2.1 1 1 0 1 1 1 0 TFIIH C1-like domain HypA PF01155.19 ETS77715.1 - 5.9 6.9 6.4 57 3.8 6.4 2.2 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Glyco_hydro_61 PF03443.14 ETS77716.1 - 3.1e-56 190.6 0.3 3.6e-56 190.4 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 UQ_con PF00179.26 ETS77717.1 - 3.1e-11 43.1 0.0 5.6e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FAF PF11250.8 ETS77717.1 - 0.022 15.0 0.2 0.098 12.9 0.1 2.1 2 0 0 2 2 2 0 Fantastic Four meristem regulator F-box-like PF12937.7 ETS77717.1 - 0.023 14.6 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 F-box-like FAD_binding_3 PF01494.19 ETS77718.1 - 4.1e-06 26.3 0.2 0.053 12.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ETS77718.1 - 1.4e-05 24.5 0.0 0.003 16.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ETS77718.1 - 0.00046 19.6 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ETS77718.1 - 0.00074 19.7 0.3 0.0017 18.5 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS77718.1 - 0.0097 15.9 0.0 0.8 9.7 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding GP63 PF17471.2 ETS77718.1 - 0.016 15.3 0.0 0.045 13.9 0.0 1.7 1 0 0 1 1 1 0 Gene product 63 DAO PF01266.24 ETS77718.1 - 0.029 14.0 0.2 0.057 13.0 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Fungus-induced PF10917.8 ETS77719.1 - 0.011 16.1 0.3 0.089 13.1 0.1 2.1 2 0 0 2 2 2 0 Fungus-induced protein Abhydrolase_4 PF08386.10 ETS77720.1 - 2.3e-16 59.8 0.0 6.5e-16 58.3 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 ETS77720.1 - 1.2e-13 51.3 0.2 3.6e-11 43.2 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Iso_dh PF00180.20 ETS77721.1 - 3.4e-89 299.4 0.0 3.8e-89 299.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4875 PF16175.5 ETS77721.1 - 0.063 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) Fungal_trans PF04082.18 ETS77722.1 - 3.1e-25 88.7 0.1 5.4e-25 87.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PARP_regulatory PF01358.18 ETS77722.1 - 0.12 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit Zn_clus PF00172.18 ETS77723.1 - 7.4e-07 29.2 10.9 1e-06 28.7 10.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 ETS77726.1 - 5.6e-66 222.9 0.0 7.5e-66 222.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS77726.1 - 1.6e-38 132.4 0.0 4e-38 131.2 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 ETS77726.1 - 8.2e-06 25.6 2.6 5.6e-05 22.9 2.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS77726.1 - 0.00016 21.8 0.2 0.00047 20.3 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS77726.1 - 0.00019 20.6 1.0 0.007 15.5 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 ETS77726.1 - 0.0009 18.6 0.2 0.036 13.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS77726.1 - 0.0018 17.6 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 ETS77726.1 - 0.0054 16.0 0.3 0.055 12.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS77726.1 - 0.012 14.4 0.3 0.045 12.5 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 ETS77726.1 - 0.014 14.5 0.1 0.023 13.8 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 ETS77726.1 - 0.094 12.7 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 ETS77726.1 - 0.12 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 ETS77726.1 - 0.37 11.4 1.9 4.5 7.9 0.3 2.9 2 2 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS77727.1 - 2.3e-14 53.4 0.0 3.3e-14 52.9 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS77727.1 - 3.4e-05 23.6 0.5 9.8e-05 22.1 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS77727.1 - 3.9e-05 23.0 0.8 0.13 11.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS77727.1 - 0.0017 18.4 0.5 1.8 8.6 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 ETS77727.1 - 0.0022 16.9 0.6 0.066 12.0 0.1 2.6 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.6 ETS77727.1 - 0.0029 17.8 0.0 0.0064 16.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ETS77727.1 - 0.035 14.7 1.6 2.3 8.8 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS77727.1 - 0.093 11.8 0.5 0.14 11.2 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 ETS77727.1 - 0.57 9.4 2.2 16 4.6 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.7 ETS77728.1 - 3.3e-22 80.2 3.7 3.8e-22 80.0 3.7 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS77728.1 - 3e-18 66.4 0.0 2.6e-15 56.7 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS77728.1 - 2.1e-16 59.9 0.0 2.9e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 ETS77728.1 - 5.8e-07 29.9 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 ETS77728.1 - 1.4e-06 28.3 0.2 0.00033 20.6 0.2 2.1 1 1 0 1 1 1 1 Serine hydrolase FSH1 PF03959.13 ETS77728.1 - 0.0033 17.1 0.0 0.0068 16.1 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 ETS77728.1 - 0.0047 16.7 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Lipase_3 PF01764.25 ETS77728.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 ETS77728.1 - 0.01 15.6 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_4 PF08386.10 ETS77728.1 - 0.038 14.1 0.0 0.071 13.2 0.0 1.5 1 1 0 1 1 1 0 TAP-like protein Peptidase_S10 PF00450.22 ETS77728.1 - 0.061 12.7 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase DUF900 PF05990.12 ETS77728.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Esterase PF00756.20 ETS77728.1 - 0.099 12.3 0.0 0.68 9.5 0.0 2.1 2 0 0 2 2 2 0 Putative esterase LIDHydrolase PF10230.9 ETS77728.1 - 0.17 11.4 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase COesterase PF00135.28 ETS77729.1 - 2.3e-97 327.0 0.0 2.8e-97 326.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS77729.1 - 1.5e-08 34.7 0.2 4.1e-07 30.1 0.2 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold QRPTase_C PF01729.19 ETS77730.1 - 2.1e-56 190.3 0.1 2.6e-56 190.0 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 ETS77730.1 - 9.6e-17 60.8 0.0 4.1e-16 58.8 0.0 2.1 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain IGPS PF00218.21 ETS77730.1 - 0.091 11.9 0.0 0.64 9.1 0.0 2.0 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Gly_transf_sug PF04488.15 ETS77732.1 - 2.2e-13 50.7 0.0 5e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif AMP-binding PF00501.28 ETS77733.1 - 4.2e-87 292.5 0.0 5.3e-87 292.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS77733.1 - 7e-19 68.6 0.1 2.1e-18 67.0 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pox_A14 PF05767.12 ETS77734.1 - 0.056 13.6 1.3 0.18 12.0 1.3 1.9 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF3623 PF12291.8 ETS77734.1 - 0.24 10.6 9.3 0.064 12.4 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3623) Metallophos PF00149.28 ETS77735.1 - 1.7e-16 61.3 0.1 3.1e-16 60.5 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 ETS77735.1 - 4.4e-13 49.6 1.4 9.6e-13 48.5 1.4 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 ETS77735.1 - 1.3e-12 48.4 0.1 3.8e-12 46.9 0.1 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD_N PF16655.5 ETS77735.1 - 0.00022 21.7 0.1 0.011 16.3 0.1 2.3 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain Glyco_hydro_3_C PF01915.22 ETS77736.1 - 3.2e-45 154.6 0.0 6e-45 153.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS77736.1 - 2.3e-40 138.9 0.0 3.7e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS77736.1 - 2.3e-19 69.3 0.2 4.3e-19 68.4 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain AP_endonuc_2 PF01261.24 ETS77737.1 - 1.8e-40 138.7 0.0 2.4e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Oxysterol_BP PF01237.18 ETS77738.1 - 7.6e-53 179.7 0.0 6.5e-47 160.1 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Zn-C2H2_12 PF18112.1 ETS77739.1 - 0.11 13.0 0.4 0.23 12.0 0.4 1.5 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Peptidase_S41 PF03572.18 ETS77740.1 - 2.8e-07 30.3 0.0 1.1e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 Peptidase family S41 TANGO2 PF05742.12 ETS77743.1 - 6.3e-58 196.8 0.0 7.6e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Tyrosinase PF00264.20 ETS77744.1 - 1.9e-40 139.5 0.6 2.4e-40 139.2 0.6 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Peptidase_M3 PF01432.20 ETS77746.1 - 3.1e-90 303.6 0.0 3.8e-90 303.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Polysacc_deac_1 PF01522.21 ETS77747.1 - 2.6e-30 104.9 0.0 4.1e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ETS77747.1 - 1.4e-11 44.6 24.1 2.3e-11 44.0 24.1 1.4 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_57 PF03065.15 ETS77747.1 - 0.0066 15.7 0.0 0.013 14.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 CN_hydrolase PF00795.22 ETS77749.1 - 8.9e-34 117.0 0.0 1.4e-33 116.4 0.0 1.3 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase FAD_binding_1 PF00667.20 ETS77750.1 - 7.6e-63 212.0 0.0 2.4e-62 210.4 0.0 1.9 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 ETS77750.1 - 3.1e-09 37.4 0.0 1.1e-08 35.7 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 ETS77750.1 - 7.3e-09 35.9 0.2 3.1e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 ETS77750.1 - 1.7e-08 34.6 0.4 5.4e-08 33.1 0.4 1.9 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II FAD_binding_6 PF00970.24 ETS77750.1 - 0.17 12.3 0.0 4.1 7.8 0.0 3.1 3 0 0 3 3 3 0 Oxidoreductase FAD-binding domain MmgE_PrpD PF03972.14 ETS77751.1 - 1.3e-88 297.4 0.0 1.6e-88 297.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Anillin_N PF16018.5 ETS77751.1 - 0.033 14.8 0.1 2.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Anillin N-terminus SDH_alpha PF03313.15 ETS77751.1 - 0.77 9.4 4.5 1.3 8.7 4.5 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain Zn_clus PF00172.18 ETS77752.1 - 3.6e-07 30.2 12.5 5.8e-07 29.5 12.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS77752.1 - 0.00019 20.3 0.1 0.00034 19.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_2 PF04909.14 ETS77753.1 - 1.4e-31 110.4 0.0 1.7e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Peptidase_S58 PF03576.14 ETS77754.1 - 4.5e-110 367.9 0.2 5.1e-110 367.7 0.2 1.0 1 0 0 1 1 1 1 Peptidase family S58 Fe-ADH PF00465.19 ETS77755.1 - 2.5e-104 349.0 0.0 3.1e-104 348.7 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ETS77755.1 - 4e-16 59.5 0.0 1.1e-12 48.2 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 ETS77755.1 - 0.001 18.8 1.1 0.0029 17.3 0.1 2.2 2 1 0 2 2 2 1 Periplasmic binding protein Pkinase PF00069.25 ETS77756.1 - 1.7e-71 240.7 0.0 2.5e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS77756.1 - 1.2e-45 155.9 0.0 2.1e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ETS77756.1 - 4.2e-17 62.2 0.2 1.3e-16 60.7 0.0 2.0 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 ETS77756.1 - 7.6e-07 28.7 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ETS77756.1 - 1.1e-06 27.8 0.0 1.1e-06 27.8 0.0 2.0 3 0 0 3 3 3 1 Fungal protein kinase Haspin_kinase PF12330.8 ETS77756.1 - 0.041 12.8 0.2 0.083 11.8 0.2 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 ETS77756.1 - 0.078 12.3 0.3 0.35 10.2 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ETS77756.1 - 0.16 11.9 3.0 0.35 10.8 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family KH_1 PF00013.29 ETS77757.1 - 7.6e-98 320.4 32.3 1.3e-14 53.7 0.1 13.9 15 0 0 15 15 15 9 KH domain KH_2 PF07650.17 ETS77757.1 - 3e-12 46.2 23.1 0.029 14.2 0.5 8.9 8 1 1 9 9 9 4 KH domain SLS PF14611.6 ETS77757.1 - 1.6e-11 44.5 9.2 0.024 14.5 0.1 7.5 3 3 4 7 7 7 4 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 ETS77757.1 - 0.00062 19.6 6.2 0.19 11.6 0.2 5.8 6 0 0 6 6 6 1 KH domain BON PF04972.17 ETS77757.1 - 0.3 11.4 2.9 4.3 7.7 0.0 4.0 4 0 0 4 4 4 0 BON domain LPD5 PF18799.1 ETS77757.1 - 0.38 11.2 3.7 2.7 8.4 0.0 4.0 4 0 0 4 4 4 0 Large polyvalent protein-associated domain 5 NICE-3 PF07406.11 ETS77758.1 - 0.06 13.3 0.7 0.082 12.9 0.7 1.2 1 0 0 1 1 1 0 NICE-3 protein LapA_dom PF06305.11 ETS77758.1 - 0.092 12.6 1.1 0.14 12.0 1.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain NUC153 PF08159.12 ETS77759.1 - 7.7e-13 48.0 1.9 1.4e-12 47.2 1.9 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 ETS77759.1 - 4.3e-07 30.5 0.1 0.074 13.9 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS77759.1 - 0.077 13.3 0.0 0.44 10.9 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Med13_C PF06333.12 ETS77760.1 - 2.8e-94 316.1 1.5 2.8e-94 316.1 1.5 2.4 3 0 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 ETS77760.1 - 1.7e-31 109.8 1.3 4.6e-31 108.4 0.8 1.8 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 ETS77760.1 - 3.9e-14 53.1 0.1 2.4e-06 27.5 0.1 2.8 2 0 0 2 2 2 2 MID domain of medPIWI R3H-assoc PF13902.6 ETS77760.1 - 0.15 12.4 0.4 0.71 10.2 0.1 2.2 2 0 0 2 2 2 0 R3H-associated N-terminal domain p450 PF00067.22 ETS77762.1 - 6.1e-56 190.1 0.0 8.3e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PNP_UDP_1 PF01048.20 ETS77763.1 - 5.1e-41 140.5 0.1 6.4e-41 140.1 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DHDPS PF00701.22 ETS77764.1 - 5.3e-38 130.4 0.0 6.4e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.16 ETS77765.1 - 1.4e-36 126.2 29.5 1.4e-36 126.2 29.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 ETS77765.1 - 0.13 12.1 0.1 1.2 8.9 0.0 2.3 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) COPI_assoc PF08507.10 ETS77765.1 - 2.6 8.1 9.0 0.47 10.5 1.0 2.9 3 0 0 3 3 3 0 COPI associated protein Fungal_trans PF04082.18 ETS77766.1 - 2.7e-21 75.8 0.0 4.3e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS77766.1 - 1.5e-08 34.6 9.3 2.6e-08 33.8 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.18 ETS77767.1 - 1.4e-07 31.2 12.1 4.4e-06 26.2 12.1 2.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF5078 PF16877.5 ETS77767.1 - 0.11 13.0 0.8 0.59 10.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5078) DUF4145 PF13643.6 ETS77767.1 - 0.14 12.3 0.6 13 6.0 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4145) DOPA_dioxygen PF08883.11 ETS77768.1 - 7.5e-41 138.6 0.1 9.7e-41 138.3 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family HLH PF00010.26 ETS77769.1 - 1.2e-15 57.2 0.0 3.2e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_M24 PF00557.24 ETS77770.1 - 2.7e-49 167.7 0.0 3.9e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ETS77770.1 - 4.6e-32 110.3 0.0 7.3e-32 109.7 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.10 ETS77771.1 - 9.4e-44 148.7 0.0 2.7e-43 147.2 0.0 1.9 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 ETS77771.1 - 4.7e-21 74.6 0.3 4.7e-21 74.6 0.3 2.0 2 0 0 2 2 2 1 DBF zinc finger BRCT PF00533.26 ETS77771.1 - 0.014 15.7 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 ETS77771.1 - 0.017 15.0 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain BRCT_2 PF16589.5 ETS77771.1 - 0.025 15.0 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Tyrosinase PF00264.20 ETS77773.1 - 9.5e-51 173.2 0.0 1.2e-50 172.9 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase 4HBT PF03061.22 ETS77774.1 - 0.053 13.9 0.5 0.48 10.8 0.1 2.2 2 0 0 2 2 2 0 Thioesterase superfamily APG12 PF04110.13 ETS77775.1 - 8e-26 90.3 0.0 1e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 ETS77775.1 - 0.0002 21.5 0.0 0.00025 21.2 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.15 ETS77776.1 - 1.2e-103 346.0 0.6 1.4e-103 345.8 0.6 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 ETS77776.1 - 8.6e-10 38.5 0.7 1.6e-09 37.6 0.7 1.5 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase NAD_binding_10 PF13460.6 ETS77777.1 - 7e-16 58.6 0.5 1.3e-15 57.8 0.2 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 ETS77777.1 - 1.7e-15 57.2 0.2 3.1e-15 56.4 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 ETS77777.1 - 2.4e-09 37.6 0.1 3.7e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ETS77777.1 - 3.8e-06 26.5 0.1 7.8e-06 25.5 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ETS77777.1 - 0.0009 18.5 0.1 0.0049 16.1 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein ApbA PF02558.16 ETS77777.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DapB_N PF01113.20 ETS77777.1 - 0.0011 19.0 0.5 0.0023 18.0 0.5 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 ETS77777.1 - 0.0035 16.4 0.1 0.007 15.4 0.1 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 ETS77777.1 - 0.0038 17.3 0.3 0.0056 16.7 0.3 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 ETS77777.1 - 0.0039 17.7 0.4 0.0087 16.6 0.4 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 ETS77777.1 - 0.0043 17.5 0.1 0.0073 16.7 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 ETS77777.1 - 0.038 13.9 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 KR domain GFO_IDH_MocA PF01408.22 ETS77777.1 - 0.1 13.5 0.1 0.18 12.7 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pigment_DH PF06324.11 ETS77777.1 - 0.1 12.7 0.4 1.2 9.4 0.1 2.4 2 0 0 2 2 2 0 Pigment-dispersing hormone (PDH) PglD_N PF17836.1 ETS77777.1 - 0.16 12.6 0.0 0.6 10.8 0.1 1.9 2 0 0 2 2 2 0 PglD N-terminal domain Pkinase PF00069.25 ETS77779.1 - 2.9e-25 89.1 0.0 1.2e-24 87.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS77779.1 - 7.8e-15 54.8 0.0 1.7e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ETS77779.1 - 0.00032 20.7 0.1 0.042 13.8 0.1 2.9 2 0 0 2 2 2 2 Phosphotransferase enzyme family Ank_2 PF12796.7 ETS77780.1 - 5.1e-23 81.5 1.1 7.6e-07 29.6 0.0 7.1 6 2 1 7 7 7 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS77780.1 - 2e-16 59.8 3.8 0.00025 21.3 0.0 7.8 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS77780.1 - 2.4e-15 56.6 7.1 0.026 15.1 0.0 8.8 8 2 2 10 10 10 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS77780.1 - 1.5e-13 49.5 6.9 0.031 14.8 0.1 9.2 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 ETS77780.1 - 5.6e-07 29.7 10.9 0.022 15.2 0.2 7.8 9 1 0 9 9 9 2 Ankyrin repeat Myco_arth_vir_N PF09610.10 ETS77781.1 - 2.2 8.4 4.5 3 8.0 4.5 1.2 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) PQ-loop PF04193.14 ETS77782.1 - 7.5e-39 131.3 13.3 3.4e-20 71.6 0.3 3.0 3 0 0 3 3 3 2 PQ loop repeat PEMT PF04191.13 ETS77782.1 - 0.22 11.9 2.3 16 5.9 0.0 3.3 2 1 1 3 3 3 0 Phospholipid methyltransferase S1-P1_nuclease PF02265.16 ETS77783.1 - 4.4e-71 239.7 0.2 5.2e-71 239.4 0.2 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Pal1 PF08316.11 ETS77784.1 - 0.025 15.3 6.1 0.025 15.3 6.1 2.6 2 0 0 2 2 2 0 Pal1 cell morphology protein RP-C_C PF11800.8 ETS77784.1 - 0.063 13.4 16.2 0.12 12.5 6.9 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region DDHD PF02862.17 ETS77784.1 - 0.066 13.4 11.5 0.1 12.7 4.5 2.1 2 0 0 2 2 2 0 DDHD domain SpoIIIAH PF12685.7 ETS77784.1 - 0.11 12.3 20.7 0.25 11.1 9.9 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein Zip PF02535.22 ETS77784.1 - 0.22 10.7 7.2 1.7 7.8 3.6 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 ETS77784.1 - 0.38 10.8 11.9 0.56 10.2 4.7 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CPSF100_C PF13299.6 ETS77784.1 - 0.39 10.9 12.1 0.31 11.2 5.1 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal EPL1 PF10513.9 ETS77784.1 - 0.46 10.9 21.2 1.6 9.1 12.1 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like LAT PF15234.6 ETS77784.1 - 0.55 9.9 12.2 0.019 14.7 5.4 1.9 2 0 0 2 2 2 0 Linker for activation of T-cells DUF5308 PF17233.2 ETS77784.1 - 0.6 10.3 11.6 0.51 10.6 4.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5308) TT_ORF1 PF02956.14 ETS77784.1 - 0.6 8.7 13.4 0.22 10.2 8.0 2.0 2 0 0 2 2 2 0 TT viral orf 1 MAJIN PF15077.6 ETS77784.1 - 1.8 8.3 8.2 3.1 7.5 3.7 2.3 2 0 0 2 2 2 0 Membrane-anchored junction protein Eapp_C PF10238.9 ETS77784.1 - 2 8.5 15.0 0.53 10.3 5.7 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Ctr PF04145.15 ETS77784.1 - 2 9.0 7.5 43 4.7 0.0 2.3 2 0 0 2 2 2 0 Ctr copper transporter family DUF719 PF05334.13 ETS77784.1 - 2.1 8.5 15.8 4.7 7.4 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DUF4820 PF16091.5 ETS77784.1 - 2.3 7.5 12.8 1.4 8.2 6.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) TraV PF09676.10 ETS77784.1 - 2.4 9.1 15.9 1.7 9.6 8.0 2.4 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Paramyxo_ncap PF00973.19 ETS77784.1 - 2.5 6.9 8.6 0.43 9.4 2.6 2.0 2 0 0 2 2 2 0 Paramyxovirus nucleocapsid protein WES_acyltransf PF03007.16 ETS77784.1 - 2.9 7.6 4.1 5.2 6.8 4.1 1.4 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain PTPRCAP PF15713.5 ETS77784.1 - 2.9 8.2 19.7 0.48 10.7 8.3 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Afi1 PF07792.12 ETS77784.1 - 3.1 8.3 18.1 0.69 10.4 9.7 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RR_TM4-6 PF06459.12 ETS77784.1 - 4.4 7.1 11.1 1.1 9.1 4.7 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF3807 PF12720.7 ETS77784.1 - 4.6 7.5 23.2 0.62 10.3 10.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) PPL5 PF18168.1 ETS77784.1 - 5 6.3 11.5 0.65 9.2 3.1 2.2 2 0 0 2 2 2 0 Prim-pol family 5 FAM60A PF15396.6 ETS77784.1 - 5.5 6.9 10.5 0.94 9.4 3.7 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Gti1_Pac2 PF09729.9 ETS77784.1 - 5.9 6.9 20.0 2.3 8.3 10.5 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family Sec62 PF03839.16 ETS77784.1 - 7 6.1 8.6 2 7.9 2.5 2.0 2 0 0 2 2 2 0 Translocation protein Sec62 Roughex PF06020.11 ETS77784.1 - 7.5 5.6 18.2 0.26 10.3 8.1 2.1 2 0 0 2 2 2 0 Drosophila roughex protein Presenilin PF01080.17 ETS77784.1 - 7.5 5.2 22.8 0.33 9.7 10.6 2.1 2 0 0 2 2 2 0 Presenilin Otopetrin PF03189.13 ETS77784.1 - 7.5 5.2 9.5 4.9 5.8 4.5 2.0 2 0 0 2 2 2 0 Otopetrin SLC12 PF03522.15 ETS77784.1 - 8.4 5.3 15.7 0.42 9.6 6.7 2.0 2 0 0 2 2 2 0 Solute carrier family 12 NST1 PF13945.6 ETS77784.1 - 9.5 6.3 40.3 1.6 8.8 23.7 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator POX PF07526.11 ETS77784.1 - 9.5 6.8 16.0 6.7 7.3 5.3 2.5 2 0 0 2 2 2 0 Associated with HOX HMG_box_2 PF09011.10 ETS77785.1 - 0.062 13.9 0.2 0.13 12.8 0.2 1.5 1 0 0 1 1 1 0 HMG-box domain HMMR_C PF15908.5 ETS77785.1 - 0.14 12.4 0.4 0.22 11.8 0.4 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal IBR PF01485.21 ETS77786.1 - 3.2e-10 40.1 43.4 1.1e-05 25.5 14.5 3.4 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain adh_short PF00106.25 ETS77787.1 - 1.5e-15 57.2 0.0 1.2e-14 54.3 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ETS77787.1 - 4.8e-08 33.1 0.0 6.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ETS77787.1 - 1e-07 31.8 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ETS77787.1 - 0.003 17.0 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peptidase_S58 PF03576.14 ETS77788.1 - 1.6e-78 264.3 2.4 1.9e-78 264.0 2.4 1.0 1 0 0 1 1 1 1 Peptidase family S58 DAGK_cat PF00781.24 ETS77788.1 - 0.042 13.5 2.6 0.53 9.9 0.7 2.6 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain DUF823 PF05689.11 ETS77788.1 - 0.15 11.8 0.1 1.9 8.2 0.0 2.1 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF823) T2SSM_b PF10741.9 ETS77789.1 - 0.033 14.0 0.2 4.6 7.1 0.1 2.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b DUF4298 PF14131.6 ETS77789.1 - 0.11 12.4 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) CorA PF01544.18 ETS77789.1 - 0.46 9.8 7.3 0.053 12.8 1.5 2.1 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Glyco_hydro2_C5 PF18565.1 ETS77790.1 - 1.6e-34 117.9 0.2 3e-34 117.0 0.2 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_C PF02836.17 ETS77790.1 - 5.4e-25 88.1 0.0 1.1e-24 87.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 ETS77790.1 - 4.1e-22 77.9 0.1 1.2e-21 76.3 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Glyco_hydro_2_N PF02837.18 ETS77790.1 - 7.2e-16 58.6 0.0 1.9e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 ETS77790.1 - 1.2e-14 54.9 1.2 2e-14 54.2 0.2 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Invasin_D3 PF09134.10 ETS77790.1 - 0.00013 22.2 7.1 0.00014 22.1 4.7 2.5 2 0 0 2 2 2 1 Invasin, domain 3 BetaGal_dom4_5 PF13364.6 ETS77790.1 - 0.00023 21.7 0.1 0.0033 18.0 0.0 2.7 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Big_1 PF02369.16 ETS77790.1 - 9.8 6.3 12.0 0.064 13.3 1.1 3.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 1) DUF3176 PF11374.8 ETS77791.1 - 1.4e-34 118.5 0.3 1.4e-34 118.5 0.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Tyr-DNA_phospho PF06087.12 ETS77792.1 - 2.6e-47 161.7 0.0 3.7e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 ETS77792.1 - 0.0049 16.7 0.1 0.21 11.4 0.0 2.5 2 0 0 2 2 2 1 PLD-like domain HiaBD2 PF15403.6 ETS77792.1 - 0.24 11.8 4.4 0.092 13.1 1.3 2.0 2 0 0 2 2 2 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) GPI2 PF06432.11 ETS77793.1 - 7.3e-131 435.7 1.3 8.6e-131 435.5 1.3 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Annexin PF00191.20 ETS77795.1 - 1.2e-14 54.1 0.5 0.0002 21.4 0.0 4.4 4 0 0 4 4 4 4 Annexin DUF5617 PF18493.1 ETS77795.1 - 0.048 13.8 0.2 0.12 12.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) FAD_binding_3 PF01494.19 ETS77796.1 - 4.6e-17 62.3 0.4 3e-09 36.6 0.1 3.1 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS77796.1 - 0.0057 16.9 0.1 0.016 15.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS77796.1 - 0.028 14.0 0.5 0.047 13.3 0.3 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS77796.1 - 0.05 12.8 0.1 0.13 11.5 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS77796.1 - 0.11 11.5 0.5 0.27 10.3 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 ETS77796.1 - 0.21 10.8 0.0 1.8 7.7 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ETS77797.1 - 3.3e-24 86.0 0.1 1.4e-21 77.3 0.0 2.5 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ETS77797.1 - 4.9e-15 55.5 0.1 1.4e-14 54.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS77797.1 - 6.4e-12 45.7 0.1 6.5e-11 42.4 0.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS77797.1 - 8.3e-10 38.4 0.1 5.1e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS77797.1 - 6e-07 28.9 2.1 3e-05 23.3 2.6 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 ETS77797.1 - 1.6e-06 27.1 0.2 0.00045 19.0 0.7 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 ETS77797.1 - 0.00024 20.5 0.8 0.00041 19.7 0.8 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ETS77797.1 - 0.0013 18.1 2.7 0.004 16.6 2.9 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ETS77797.1 - 0.0015 17.8 0.2 0.0042 16.4 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 ETS77797.1 - 0.0024 17.2 0.2 0.0041 16.4 0.2 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 ETS77797.1 - 0.0039 17.2 1.4 0.16 12.0 0.3 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding MCRA PF06100.11 ETS77797.1 - 0.012 14.4 0.0 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 MCRA family GIDA PF01134.22 ETS77797.1 - 0.025 13.7 3.1 0.048 12.7 1.7 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 ETS77797.1 - 0.031 14.7 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 ETS77797.1 - 0.036 12.9 0.5 2.9 6.7 0.7 2.2 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 ETS77797.1 - 0.04 13.6 0.2 0.069 12.8 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 ETS77797.1 - 0.064 12.6 0.3 0.11 11.9 0.3 1.3 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.27 ETS77797.1 - 0.15 12.7 1.8 0.81 10.3 0.9 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 ETS77797.1 - 0.15 11.6 0.1 0.6 9.7 0.1 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Lycopene_cycl PF05834.12 ETS77797.1 - 0.18 10.8 3.0 0.37 9.8 0.5 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein adh_short PF00106.25 ETS77797.1 - 0.29 10.6 0.9 0.45 9.9 0.9 1.2 1 0 0 1 1 1 0 short chain dehydrogenase SQS_PSY PF00494.19 ETS77798.1 - 1.2e-64 218.3 0.7 1.6e-64 218.0 0.7 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase FeS_assembly_P PF01883.19 ETS77798.1 - 0.037 14.2 0.0 0.08 13.1 0.0 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster assembly protein PufQ PF05398.11 ETS77798.1 - 0.16 12.1 2.0 0.17 12.0 0.2 2.0 2 0 0 2 2 2 0 PufQ cytochrome subunit FAD_binding_7 PF03441.14 ETS77799.1 - 1.2e-46 158.8 0.8 2e-46 158.1 0.6 1.4 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ETS77799.1 - 1.1e-17 64.5 0.4 2.4e-17 63.4 0.0 1.7 2 0 0 2 2 2 1 DNA photolyase Ustilago_mating PF05722.12 ETS77799.1 - 0.092 12.3 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein 4HBT PF03061.22 ETS77800.1 - 0.00075 19.8 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily zf-C2H2_4 PF13894.6 ETS77801.1 - 0.00079 20.1 20.4 0.16 12.9 2.7 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 ETS77801.1 - 0.0009 19.6 25.1 0.34 11.4 4.9 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type PTP_tm PF18861.1 ETS77801.1 - 0.01 15.9 0.4 0.018 15.0 0.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J FOXP-CC PF16159.5 ETS77801.1 - 0.044 14.4 3.2 0.049 14.3 1.7 1.9 1 1 0 1 1 1 0 FOXP coiled-coil domain MmgE_PrpD PF03972.14 ETS77803.1 - 4e-148 493.6 0.0 4.7e-148 493.4 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family TPT PF03151.16 ETS77804.1 - 7.7e-26 91.1 27.2 9.5e-26 90.8 27.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 ETS77804.1 - 0.0028 16.9 23.3 0.049 12.8 23.3 2.1 1 1 0 1 1 1 1 UAA transporter family Med31 PF05669.12 ETS77805.1 - 3.4e-37 126.3 2.6 3.8e-37 126.2 2.6 1.0 1 0 0 1 1 1 1 SOH1 TFIIS_C PF01096.18 ETS77806.1 - 1.3e-13 50.5 3.0 8e-13 48.0 0.1 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 ETS77806.1 - 7.1e-06 25.8 0.9 2e-05 24.4 0.9 1.8 1 1 0 1 1 1 1 RNA polymerases M/15 Kd subunit Nudix_N_2 PF14803.6 ETS77806.1 - 0.0017 18.2 2.5 0.0033 17.3 2.5 1.4 1 0 0 1 1 1 1 Nudix N-terminal Zn_Tnp_IS1595 PF12760.7 ETS77806.1 - 0.0087 16.0 3.9 0.015 15.3 1.2 2.2 2 0 0 2 2 2 1 Transposase zinc-ribbon domain Elf1 PF05129.13 ETS77806.1 - 0.023 14.7 0.3 0.045 13.8 0.1 1.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 ETS77806.1 - 0.067 13.6 1.9 0.13 12.6 0.1 2.0 1 1 1 2 2 2 0 Restriction alleviation protein Lar IBR PF01485.21 ETS77806.1 - 0.07 13.4 1.8 7 7.0 0.3 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_12 PF17976.1 ETS77806.1 - 0.16 12.2 2.8 5.2 7.4 2.8 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PriA_CRR PF18319.1 ETS77806.1 - 1.2 9.2 6.6 3.2 7.8 0.8 2.3 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain Ank_3 PF13606.6 ETS77807.1 - 7.5e-09 35.1 0.4 0.0072 16.7 0.0 3.9 4 1 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 ETS77807.1 - 7.2e-08 32.9 0.1 2.3e-07 31.3 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS77807.1 - 2.4e-07 31.1 0.0 7.2e-06 26.5 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 ETS77807.1 - 6.6e-05 23.2 0.0 0.18 12.3 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 ETS77807.1 - 0.0019 18.5 0.7 7.3 7.0 0.0 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) CFEM PF05730.11 ETS77808.1 - 4.2e-10 39.6 14.1 6.3e-10 39.0 14.1 1.3 1 0 0 1 1 1 1 CFEM domain Thaumatin PF00314.17 ETS77809.1 - 6.6e-70 235.1 5.4 8.2e-70 234.8 5.4 1.1 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 ETS77809.1 - 0.024 13.9 1.2 2.3 7.4 0.3 2.5 2 1 0 2 2 2 0 Beta-1,3-glucanase YmcE_antitoxin PF15939.5 ETS77809.1 - 0.086 13.0 0.0 0.37 11.0 0.0 2.0 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system Ank_4 PF13637.6 ETS77811.1 - 1.1e-18 67.4 0.6 1.2e-07 32.1 0.1 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS77811.1 - 1.8e-18 66.9 0.3 2.7e-11 43.9 0.1 3.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ETS77811.1 - 6.6e-15 54.8 1.7 0.00011 22.4 0.0 5.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ETS77811.1 - 1.5e-10 41.1 0.3 9.4e-05 22.6 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS77811.1 - 2.1e-10 39.9 0.4 0.0035 17.7 0.0 4.6 3 0 0 3 3 3 2 Ankyrin repeat MukF_M PF17192.4 ETS77811.1 - 0.00056 19.7 0.3 0.0013 18.5 0.3 1.6 1 0 0 1 1 1 1 MukF middle domain Helo_like_N PF17111.5 ETS77811.1 - 0.022 14.1 0.7 0.088 12.2 0.8 1.9 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins DHR10 PF18595.1 ETS77811.1 - 0.1 12.7 1.9 0.11 12.6 0.4 1.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF948 PF06103.11 ETS77811.1 - 0.13 12.6 1.7 19 5.6 0.7 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HSP70 PF00012.20 ETS77812.1 - 6.8e-11 41.1 0.2 2e-09 36.2 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 ETS77812.1 - 0.028 13.2 0.1 0.18 10.6 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Methyltransf_24 PF13578.6 ETS77813.1 - 2.4e-05 25.3 0.0 6.2e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS77813.1 - 0.16 12.7 0.0 0.27 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MFS_5 PF05631.14 ETS77814.1 - 2.7e-65 220.6 10.8 3.8e-65 220.1 10.8 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 ETS77814.1 - 1.4e-18 67.0 25.2 1.4e-18 67.0 25.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Gaa1 PF04114.14 ETS77814.1 - 0.041 12.9 3.6 0.058 12.4 3.6 1.2 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component DUF3938 PF13074.6 ETS77814.1 - 1 9.6 12.0 5.1 7.4 0.9 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3938) CCB1 PF12046.8 ETS77814.1 - 2.2 7.6 6.0 4.1 6.7 1.6 2.4 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B Hexokinase_2 PF03727.16 ETS77815.1 - 1.3e-76 257.2 0.0 1.8e-76 256.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ETS77815.1 - 1.7e-74 250.1 0.0 4.3e-74 248.7 0.0 1.6 2 0 0 2 2 2 1 Hexokinase Acetyltransf_1 PF00583.25 ETS77816.1 - 0.00011 22.4 0.0 0.00017 21.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS77816.1 - 0.023 15.1 0.0 0.037 14.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS77816.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf_UBZ PF18439.1 ETS77817.1 - 0.22 11.2 2.2 2.1 8.0 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Sgf11 PF08209.11 ETS77817.1 - 1.9 8.1 7.5 0.18 11.4 3.1 1.6 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Pro_isomerase PF00160.21 ETS77818.1 - 4.1e-51 173.4 0.0 4.8e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.13 ETS77819.1 - 5.6e-56 190.1 10.1 5.1e-37 127.9 3.7 2.1 2 0 0 2 2 2 2 Signal peptide peptidase CrgA PF06781.12 ETS77819.1 - 0.64 10.1 3.0 3.2 7.9 0.0 3.0 3 0 0 3 3 3 0 Cell division protein CrgA ACPS PF01648.20 ETS77820.1 - 7.4e-09 35.7 0.0 1.5e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily NUDIX PF00293.28 ETS77821.1 - 9.3e-11 41.9 0.1 2.8e-09 37.1 0.1 2.2 1 1 0 1 1 1 1 NUDIX domain DLH PF01738.18 ETS77822.1 - 2.3e-18 66.6 0.0 2.6e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family His_Phos_1 PF00300.22 ETS77824.1 - 7e-07 29.1 0.1 0.00019 21.2 0.0 3.0 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) ATP12 PF07542.11 ETS77825.1 - 2.1e-41 141.0 0.0 3.4e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein HET PF06985.11 ETS77827.1 - 2e-25 89.9 0.0 3.9e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3176 PF11374.8 ETS77828.1 - 0.0028 17.8 1.1 0.0099 16.1 1.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) p450 PF00067.22 ETS77829.1 - 2e-59 201.5 0.0 4.1e-59 200.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.7 ETS77830.1 - 2.7e-66 220.1 7.4 3.1e-11 43.7 0.3 8.2 3 1 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS77830.1 - 4.6e-60 199.3 2.8 1.2e-07 32.2 0.1 11.0 8 3 4 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS77830.1 - 1.6e-53 178.1 7.2 5.2e-07 29.8 0.0 11.1 4 3 5 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS77830.1 - 1.7e-47 153.9 0.7 0.0052 17.2 0.0 13.5 13 0 0 13 13 13 10 Ankyrin repeat Ank PF00023.30 ETS77830.1 - 7.8e-47 155.8 6.8 0.0019 18.6 0.0 12.3 12 0 0 12 12 12 11 Ankyrin repeat CorA PF01544.18 ETS77830.1 - 7.8e-09 35.3 0.4 1.9e-08 34.0 0.4 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Phage_holin_3_6 PF07332.11 ETS77830.1 - 0.044 13.8 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III MerR PF00376.23 ETS77830.1 - 0.082 12.7 0.0 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 MerR family regulatory protein Mem_trans PF03547.18 ETS77831.1 - 3.8e-52 177.0 0.1 5.9e-31 107.2 0.0 2.0 2 0 0 2 2 2 2 Membrane transport protein SLC35F PF06027.12 ETS77834.1 - 2.1e-93 313.1 23.8 2.7e-93 312.8 23.8 1.1 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 ETS77834.1 - 1.8e-08 33.7 8.9 4.4e-08 32.5 8.2 2.0 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 ETS77834.1 - 1.5e-07 31.7 40.0 9.6e-05 22.6 16.4 2.3 2 0 0 2 2 2 2 EamA-like transporter family FUSC-like PF12805.7 ETS77834.1 - 9.9 5.1 7.0 1.1 8.3 0.7 2.5 2 1 0 2 2 2 0 FUSC-like inner membrane protein yccS Metallophos PF00149.28 ETS77835.1 - 1.8e-13 51.5 1.0 2.9e-13 50.8 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ETS77835.1 - 0.03 14.5 0.7 0.95 9.6 0.2 2.9 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain RTA1 PF04479.13 ETS77836.1 - 3.3e-49 167.3 11.9 4.8e-49 166.8 11.9 1.2 1 0 0 1 1 1 1 RTA1 like protein FAD_binding_4 PF01565.23 ETS77837.1 - 9.6e-25 86.9 3.5 1.7e-24 86.1 3.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS77837.1 - 1.8e-12 47.2 0.9 3.1e-12 46.4 0.9 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 ETS77837.1 - 0.21 10.9 0.0 0.54 9.6 0.0 1.6 2 0 0 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding HET PF06985.11 ETS77838.1 - 7.4e-29 101.0 0.0 1.2e-28 100.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DHQS PF01959.16 ETS77839.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase II MFS_1 PF07690.16 ETS77840.1 - 1.1e-22 80.5 23.2 1.1e-22 80.5 23.2 3.0 1 1 2 3 3 3 1 Major Facilitator Superfamily DUF4448 PF14610.6 ETS77840.1 - 0.039 13.7 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TRI12 PF06609.13 ETS77840.1 - 0.053 11.9 8.4 0.0062 15.0 3.9 1.6 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF4131 PF13567.6 ETS77840.1 - 0.41 10.3 0.0 0.41 10.3 0.0 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF4131) UPF0139 PF03669.13 ETS77840.1 - 6 6.8 5.3 3.7 7.5 0.0 3.1 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0139) IBR PF01485.21 ETS77841.1 - 4.9e-13 49.1 33.1 2.4e-07 30.8 6.9 3.9 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 ETS77841.1 - 8.2e-05 22.6 6.3 8.2e-05 22.6 6.3 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 ETS77841.1 - 0.00049 20.4 5.7 0.00049 20.4 5.7 3.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 ETS77841.1 - 0.0011 18.9 5.6 0.0011 18.9 5.6 3.5 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ETS77841.1 - 0.0014 18.5 6.5 0.0014 18.5 6.5 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ETS77841.1 - 0.0064 16.2 3.5 0.0076 16.0 1.8 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ETS77841.1 - 0.03 14.2 1.5 0.03 14.2 1.5 3.8 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) SWIRM PF04433.17 ETS77841.1 - 0.53 10.6 0.0 0.53 10.6 0.0 2.7 3 0 0 3 3 3 0 SWIRM domain PEP-utilisers_N PF05524.13 ETS77841.1 - 1.5 9.0 9.8 0.11 12.6 1.2 2.6 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal RhoGAP PF00620.27 ETS77842.1 - 9e-49 165.2 0.1 3.3e-48 163.4 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 ETS77842.1 - 7e-13 48.7 0.3 2.7e-12 46.8 0.3 2.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DUF5321 PF17254.2 ETS77842.1 - 0.068 12.6 1.5 0.092 12.2 0.4 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5321) PhageMin_Tail PF10145.9 ETS77842.1 - 1.5 8.7 6.9 35 4.2 6.9 2.9 1 1 0 1 1 1 0 Phage-related minor tail protein STAT_alpha PF01017.20 ETS77842.1 - 1.8 8.4 12.0 0.073 13.0 1.3 2.7 1 1 1 2 2 2 0 STAT protein, all-alpha domain UPF0139 PF03669.13 ETS77843.1 - 1.2e-07 31.4 0.0 1.6e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Med12 PF09497.10 ETS77844.1 - 1.6e-27 95.5 0.4 4.6e-27 94.1 0.4 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 ETS77844.1 - 0.0033 16.4 0.0 0.019 13.8 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic Mediator 12 subunit domain TAN PF11640.8 ETS77844.1 - 0.093 12.9 0.5 0.49 10.5 0.0 2.5 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair HTH_Mga PF08280.11 ETS77844.1 - 0.14 12.2 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain PI-PLC-X PF00388.19 ETS77845.1 - 4e-61 204.9 0.0 7.1e-61 204.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 ETS77845.1 - 2.2e-42 144.0 0.2 4.3e-42 143.1 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Fungal_trans PF04082.18 ETS77846.1 - 7.9e-09 34.9 0.6 1.4e-08 34.1 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS77846.1 - 7e-07 29.3 12.2 1.1e-06 28.6 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATPgrasp_Ter PF15632.6 ETS77847.1 - 0.16 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon WSC PF01822.19 ETS77848.1 - 6.2e-24 84.0 79.7 7.3e-11 42.1 8.1 6.6 5 1 0 5 5 5 4 WSC domain RabGAP-TBC PF00566.18 ETS77849.1 - 1.8e-46 158.5 0.0 3e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 ETS77849.1 - 1.1e-05 24.9 0.4 0.014 15.3 0.3 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 ETS77849.1 - 0.0044 16.5 2.7 0.075 12.6 0.6 3.4 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 ETS77849.1 - 0.023 15.1 3.6 0.046 14.2 0.6 3.1 3 1 2 5 5 5 0 EF-hand domain pair EF-hand_5 PF13202.6 ETS77849.1 - 0.042 13.4 0.2 0.14 11.7 0.2 2.0 1 0 0 1 1 1 0 EF hand GRAM PF02893.20 ETS77849.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 GRAM domain Pkinase PF00069.25 ETS77850.1 - 4.1e-67 226.3 0.0 5.1e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS77850.1 - 1.4e-34 119.6 0.0 1.9e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS77850.1 - 1.7e-05 24.3 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ETS77850.1 - 0.00029 20.9 0.1 0.023 14.6 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ETS77850.1 - 0.02 13.8 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 ETS77850.1 - 0.025 13.6 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 ETS77850.1 - 0.066 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 ETS77851.1 - 1.8e-06 28.0 0.7 1.8e-06 28.0 0.7 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETS77851.1 - 0.018 14.6 0.1 0.037 13.6 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Exo_endo_phos PF03372.23 ETS77852.1 - 3.7e-05 23.4 0.0 0.00012 21.7 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 ETS77853.1 - 2.5e-26 92.6 0.0 3.2e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS77853.1 - 6.9e-14 51.7 0.0 9.5e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ETS77853.1 - 3.7e-09 35.9 0.0 6.4e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ETS77853.1 - 0.00017 21.6 0.0 0.0014 18.6 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family DUF829 PF05705.14 ETS77854.1 - 4.4e-50 170.8 0.0 5.1e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DLH PF01738.18 ETS77854.1 - 0.0046 16.5 0.1 0.0079 15.8 0.1 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family ADH_N PF08240.12 ETS77858.1 - 5.8e-11 42.2 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS77858.1 - 8e-10 38.8 0.0 1.9e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Dioxygenase_C PF00775.21 ETS77859.1 - 1.4e-07 31.1 0.0 2.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase TrbI PF03743.14 ETS77860.1 - 0.21 11.4 6.8 0.54 10.1 6.3 2.0 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein SRP-alpha_N PF04086.13 ETS77861.1 - 6.5e-81 272.4 0.0 8.5e-81 272.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 ETS77861.1 - 5.2e-53 179.6 0.1 8.8e-53 178.9 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MeaB PF03308.16 ETS77861.1 - 1.3e-08 34.1 0.2 2.3e-08 33.4 0.2 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54_N PF02881.19 ETS77861.1 - 9.6e-08 32.1 0.0 2.7e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 ETS77861.1 - 0.00024 20.9 0.1 0.00049 19.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ETS77861.1 - 0.0026 18.2 0.1 0.0092 16.4 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ETS77861.1 - 0.0041 16.7 0.1 0.0087 15.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ETS77861.1 - 0.0059 16.8 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ETS77861.1 - 0.0068 16.5 0.4 0.46 10.5 0.1 2.6 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 ETS77861.1 - 0.016 14.9 0.1 0.044 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ETS77861.1 - 0.018 14.7 0.2 0.042 13.4 0.2 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 ETS77861.1 - 0.023 14.8 0.2 0.086 12.9 0.2 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_31 PF13614.6 ETS77861.1 - 0.032 14.1 0.1 0.081 12.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain NAD_binding_10 PF13460.6 ETS77861.1 - 0.049 13.5 0.5 0.15 11.9 0.2 1.9 2 0 0 2 2 2 0 NAD(P)H-binding APS_kinase PF01583.20 ETS77861.1 - 0.074 12.9 0.2 0.2 11.6 0.1 1.9 2 1 0 2 2 2 0 Adenylylsulphate kinase AAA_16 PF13191.6 ETS77861.1 - 0.14 12.6 0.0 0.43 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain YIF1 PF03878.15 ETS77862.1 - 3.3e-96 321.4 1.0 3.8e-96 321.2 1.0 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 ETS77862.1 - 0.0045 16.7 8.2 0.0045 16.7 8.2 1.7 2 0 0 2 2 2 1 Yip1 domain Mpv17_PMP22 PF04117.12 ETS77863.1 - 9.7e-15 54.5 8.3 2.7e-14 53.1 0.6 2.4 2 0 0 2 2 2 2 Mpv17 / PMP22 family HSP70 PF00012.20 ETS77864.1 - 2e-261 868.5 15.2 2.2e-261 868.3 15.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ETS77864.1 - 3.1e-19 69.0 2.0 8.9e-18 64.2 0.3 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 ETS77864.1 - 0.0016 18.8 6.7 1.9 9.0 0.1 3.8 3 2 0 3 3 3 2 Cell division protein FtsA Radial_spoke_3 PF06098.11 ETS77864.1 - 0.013 14.8 1.1 0.029 13.7 1.1 1.5 1 0 0 1 1 1 0 Radial spoke protein 3 DDR PF08841.10 ETS77864.1 - 0.014 14.4 0.2 0.13 11.3 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain HEPPP_synt_1 PF07307.11 ETS77864.1 - 0.097 12.3 1.1 0.2 11.2 1.1 1.4 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Hydantoinase_A PF01968.18 ETS77864.1 - 0.31 10.2 2.8 0.65 9.2 0.1 2.7 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase Sugar_tr PF00083.24 ETS77865.1 - 3.9e-33 115.0 28.8 6.5e-19 68.1 11.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ETS77865.1 - 1.9e-26 92.9 40.3 9.7e-14 51.0 25.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PEX11 PF05648.14 ETS77866.1 - 3.9e-72 242.3 0.3 4.4e-72 242.2 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF2805 PF10985.8 ETS77866.1 - 0.15 12.5 2.1 0.25 11.8 0.0 2.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2805) Ribosomal_S7 PF00177.21 ETS77867.1 - 1.5e-22 79.9 0.0 2.9e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e p450 PF00067.22 ETS77868.1 - 4.7e-32 111.3 0.0 2.8e-30 105.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Thiolase_N PF00108.23 ETS77869.1 - 4.8e-71 239.2 5.4 8.3e-71 238.4 5.4 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ETS77869.1 - 5.7e-45 151.9 0.2 1.1e-44 151.0 0.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ETS77869.1 - 0.032 13.8 0.4 0.032 13.8 0.4 2.0 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 ETS77869.1 - 0.038 14.2 0.0 0.13 12.4 0.0 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Peptidase_S49 PF01343.18 ETS77869.1 - 0.089 12.7 0.1 0.25 11.3 0.1 1.7 2 0 0 2 2 2 0 Peptidase family S49 OCD_Mu_crystall PF02423.15 ETS77870.1 - 4.4e-10 39.0 0.1 6.2e-05 22.1 0.0 2.7 2 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Pro_CA PF00484.19 ETS77871.1 - 1.8e-44 151.8 0.1 2.1e-44 151.5 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Ribosomal_L7Ae PF01248.26 ETS77872.1 - 2.1e-21 75.5 0.5 3.4e-21 74.8 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zn-ribbon_14 PF16503.5 ETS77873.1 - 1.7e-18 65.8 3.9 1.7e-18 65.8 3.9 3.7 4 0 0 4 4 4 1 Zinc-ribbon ATP_bind_3 PF01171.20 ETS77873.1 - 1.1e-17 64.4 0.0 1.8e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 PP-loop family RecR PF02132.15 ETS77873.1 - 0.0041 16.7 0.5 0.0041 16.7 0.5 3.7 4 0 0 4 4 4 1 RecR protein DUF4428 PF14471.6 ETS77873.1 - 0.015 15.2 0.6 0.015 15.2 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) tRNA_Me_trans PF03054.16 ETS77873.1 - 0.05 12.4 0.0 0.085 11.6 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase MWFE PF15879.5 ETS77874.1 - 5.5e-34 116.1 1.1 7.1e-34 115.8 1.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit MOZ_SAS PF01853.18 ETS77875.1 - 1.4e-76 256.1 0.0 2.1e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 ETS77875.1 - 7.6e-21 73.5 3.4 1.7e-20 72.4 3.4 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 ETS77875.1 - 1.8e-07 31.2 7.2 7.5e-07 29.1 7.2 2.2 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 ETS77875.1 - 2.2e-05 24.3 7.0 2.2e-05 24.3 7.0 2.3 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 ETS77875.1 - 0.024 14.2 2.2 0.067 12.8 2.2 1.8 1 0 0 1 1 1 0 PHD-finger Acetyltransf_7 PF13508.7 ETS77875.1 - 0.076 13.5 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-MIZ PF02891.20 ETS77875.1 - 0.24 11.2 2.0 0.74 9.6 2.0 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_9 PF13901.6 ETS77875.1 - 0.42 10.6 3.3 0.79 9.7 3.3 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zinc_ribbon_10 PF10058.9 ETS77875.1 - 5.7 6.7 6.2 4.5 7.1 1.7 2.8 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein ENTH PF01417.20 ETS77876.1 - 2e-49 166.8 0.0 2.9e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 ETS77876.1 - 0.001 18.1 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 ANTH domain UIM PF02809.20 ETS77876.1 - 0.002 17.9 4.5 0.0089 15.9 0.2 2.8 2 0 0 2 2 2 1 Ubiquitin interaction motif DUF4264 PF14084.6 ETS77876.1 - 0.013 15.1 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) VHS PF00790.19 ETS77876.1 - 0.078 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 VHS domain Usp PF00582.26 ETS77877.1 - 2.5e-22 79.9 4.7 4.7e-13 49.9 0.2 2.8 3 0 0 3 3 3 2 Universal stress protein family TPPK_C PF12555.8 ETS77878.1 - 0.087 12.9 0.6 0.21 11.6 0.6 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal RRM_1 PF00076.22 ETS77879.1 - 2.4e-82 270.7 3.6 6.1e-22 77.2 0.1 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 ETS77879.1 - 3.4e-28 97.6 1.2 1.5e-27 95.6 0.6 2.4 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 ETS77879.1 - 9.7e-10 38.1 0.0 0.0024 17.5 0.0 4.8 2 1 3 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ETS77879.1 - 8.1e-06 25.6 0.0 0.018 14.9 0.0 4.0 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_7 PF16367.5 ETS77879.1 - 6.4e-05 23.0 0.3 1.6 8.9 0.0 5.2 5 1 0 5 5 5 1 RNA recognition motif YflT PF11181.8 ETS77879.1 - 0.0017 18.8 2.5 0.23 12.0 0.2 3.3 3 0 0 3 3 3 1 Heat induced stress protein YflT Nup35_RRM_2 PF14605.6 ETS77879.1 - 0.027 14.5 2.4 27 4.8 0.1 4.6 4 1 0 4 4 4 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 ETS77879.1 - 0.044 13.5 0.7 12 5.7 0.0 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain Nefa_Nip30_N PF10187.9 ETS77879.1 - 0.063 13.6 0.3 0.063 13.6 0.3 3.8 4 0 0 4 4 3 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 TC1 PF15063.6 ETS77879.1 - 0.083 12.8 0.0 6.5 6.7 0.0 2.8 2 0 0 2 2 2 0 Thyroid cancer protein 1 Limkain-b1 PF11608.8 ETS77879.1 - 0.089 12.9 0.2 20 5.3 0.0 3.2 3 0 0 3 3 3 0 Limkain b1 NPR3 PF03666.13 ETS77879.1 - 1.2 7.8 3.8 2.1 7.0 3.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HECT PF00632.25 ETS77880.1 - 4.2e-79 266.2 0.0 6e-79 265.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 ETS77880.1 - 0.11 12.3 4.2 0.3 11.0 4.2 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif RCC1 PF00415.18 ETS77881.1 - 5.2e-23 81.4 0.1 1.5e-05 25.5 0.1 5.6 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 ETS77881.1 - 7e-15 55.2 0.0 5.1e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 ETS77881.1 - 5.6e-10 39.6 0.2 2.2e-09 37.6 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.6 ETS77881.1 - 2.4e-08 33.6 1.0 2.4e-08 33.6 1.0 4.5 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 ETS77881.1 - 6.8e-07 29.8 0.1 1.6e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS77881.1 - 2.2e-05 24.5 0.2 0.1 13.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat PP1_bind PF15276.6 ETS77881.1 - 0.015 15.6 2.2 5.7 7.3 0.1 2.9 2 0 0 2 2 2 0 Protein phosphatase 1 binding Ank_5 PF13857.6 ETS77881.1 - 0.017 15.4 0.0 0.12 12.8 0.0 2.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Mito_carr PF00153.27 ETS77882.1 - 4.9e-67 221.9 1.7 2.7e-23 81.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 ETS77882.1 - 0.091 13.1 2.4 0.43 11.0 1.0 2.8 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Glyco_hydro_43 PF04616.14 ETS77883.1 - 8.1e-64 215.7 1.7 1.1e-63 215.3 1.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ETS77883.1 - 3.9e-18 65.9 0.0 3.3e-17 62.9 0.0 2.1 1 1 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Amidoligase_2 PF12224.8 ETS77884.1 - 8.8e-17 61.6 0.3 6.4e-11 42.4 0.2 3.2 2 1 1 3 3 3 2 Putative amidoligase enzyme p450 PF00067.22 ETS77887.1 - 1.1e-50 172.8 0.0 1.4e-50 172.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AHJR-like PF18743.1 ETS77887.1 - 0.026 14.1 0.0 0.51 9.9 0.0 2.3 2 0 0 2 2 2 0 REase_AHJR-like DUF2471 PF10616.9 ETS77887.1 - 0.096 13.2 0.0 0.31 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2471) Mito_carr PF00153.27 ETS77889.1 - 2e-53 178.3 3.9 2.6e-19 68.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DNA_pol_phi PF04931.13 ETS77889.1 - 0.08 11.0 0.0 0.099 10.7 0.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi adh_short_C2 PF13561.6 ETS77890.1 - 6.1e-37 127.4 0.2 2.7e-36 125.3 0.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS77890.1 - 1.3e-33 116.2 0.1 3.9e-33 114.6 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS77890.1 - 3.8e-10 40.0 0.2 9.4e-10 38.7 0.1 1.7 2 0 0 2 2 2 1 KR domain LacAB_rpiB PF02502.18 ETS77890.1 - 0.035 14.1 1.0 3 7.8 0.5 2.3 2 0 0 2 2 2 0 Ribose/Galactose Isomerase Sacchrp_dh_NADP PF03435.18 ETS77890.1 - 0.097 12.9 0.1 0.17 12.1 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain BUD22 PF09073.10 ETS77891.1 - 7.1e-97 325.5 56.4 9.9e-96 321.7 56.4 2.0 1 1 0 1 1 1 1 BUD22 FemAB_like PF04339.12 ETS77892.1 - 0.15 11.2 1.1 0.26 10.4 1.1 1.3 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition ESP PF16590.5 ETS77892.1 - 0.29 11.4 1.2 0.97 9.7 1.2 1.8 1 0 0 1 1 1 0 Exocrine gland-secreting peptide CCDC53 PF10152.9 ETS77893.1 - 0.045 14.2 0.3 0.045 14.2 0.3 5.0 4 2 0 4 4 4 0 Subunit CCDC53 of WASH complex DUF2730 PF10805.8 ETS77893.1 - 0.05 13.7 27.0 0.51 10.5 4.4 6.7 1 1 5 7 7 7 0 Protein of unknown function (DUF2730) ABC_tran_CTD PF16326.5 ETS77893.1 - 0.19 12.0 30.5 0.73 10.1 4.4 6.8 4 1 1 6 6 6 0 ABC transporter C-terminal domain ALMS_repeat PF18727.1 ETS77893.1 - 0.61 10.0 3.9 1.3 9.0 3.1 2.0 2 0 0 2 2 2 0 Alstrom syndrome repeat Baculo_PEP_C PF04513.12 ETS77893.1 - 1.7 8.7 36.0 0.038 14.0 1.7 5.2 2 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin PF00435.21 ETS77893.1 - 1.9 9.0 34.7 0.3 11.6 4.5 5.3 2 2 2 5 5 5 0 Spectrin repeat TRAUB PF08164.12 ETS77894.1 - 1.6e-29 102.3 0.2 1.6e-29 102.3 0.2 3.0 3 1 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 ETS77894.1 - 5.8e-23 82.1 3.4 5.8e-23 82.1 3.4 3.3 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor DUF2254 PF10011.9 ETS77894.1 - 0.1 11.4 0.4 0.19 10.5 0.4 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) ParA PF10609.9 ETS77895.1 - 2.6e-95 318.5 0.3 3.1e-95 318.3 0.3 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 ETS77895.1 - 9.9e-13 48.3 0.0 1.9e-11 44.1 0.0 2.6 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ETS77895.1 - 1.3e-09 38.2 0.1 9.5e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 ETS77895.1 - 5.1e-06 25.9 1.2 0.00017 20.9 0.3 2.7 1 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.6 ETS77895.1 - 1.8e-05 24.7 1.2 0.0014 18.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 ETS77895.1 - 2.8e-05 23.5 0.0 4.2e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 ETS77895.1 - 0.00019 21.0 0.0 0.028 13.9 0.0 2.3 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 ETS77895.1 - 0.0033 17.0 0.1 0.0086 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain CBP_BcsQ PF06564.12 ETS77895.1 - 0.0053 16.3 0.3 0.06 12.8 0.2 2.0 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 ETS77895.1 - 0.025 13.6 0.1 0.025 13.6 0.1 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 ETS77895.1 - 0.047 13.5 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop VirC1 PF07015.11 ETS77895.1 - 0.1 11.9 0.2 0.21 10.9 0.1 1.5 2 0 0 2 2 2 0 VirC1 protein Tudor_3 PF18115.1 ETS77896.1 - 7.9e-06 25.6 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 ETS77896.1 - 0.0016 18.5 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF1325 PF07039.11 ETS77896.1 - 0.019 15.0 0.1 0.043 13.9 0.1 1.5 1 0 0 1 1 1 0 SGF29 tudor-like domain CCDC-167 PF15188.6 ETS77896.1 - 0.025 14.9 0.3 0.045 14.1 0.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 LBR_tudor PF09465.10 ETS77896.1 - 0.05 13.4 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Fis1_TPR_C PF14853.6 ETS77896.1 - 0.094 12.8 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Mito_fiss_reg PF05308.11 ETS77896.1 - 2.8 8.0 9.8 1.5 8.9 3.2 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Glyco_hydro_28 PF00295.17 ETS77897.1 - 1.8e-123 411.8 19.8 2e-123 411.6 19.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2111 PF09884.9 ETS77897.1 - 0.062 13.4 0.3 0.37 10.9 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2111) Aspzincin_M35 PF14521.6 ETS77898.1 - 9.5e-33 113.8 1.3 2.5e-32 112.4 1.3 1.7 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 ETS77898.1 - 6.6e-25 87.7 13.8 8.6e-25 87.4 13.8 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HRXXH PF13933.6 ETS77898.1 - 5.4e-05 22.9 0.3 5.4e-05 22.9 0.3 1.8 2 0 0 2 2 2 1 Putative peptidase family CARDB PF07705.11 ETS77898.1 - 0.031 14.5 0.6 0.031 14.5 0.6 2.2 2 0 0 2 2 2 0 CARDB DUF1859 PF08948.10 ETS77898.1 - 0.082 12.9 0.4 0.33 10.9 0.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1859) Peptidase_M4 PF01447.18 ETS77898.1 - 0.7 10.4 5.1 0.6 10.6 0.2 2.7 3 0 0 3 3 3 0 Thermolysin metallopeptidase, catalytic domain NMT1 PF09084.11 ETS77899.1 - 1.8e-76 256.8 0.0 2.3e-76 256.5 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 ETS77899.1 - 0.00081 19.2 0.1 0.33 10.6 0.0 3.1 3 1 0 3 3 3 1 NMT1-like family Phosphonate-bd PF12974.7 ETS77899.1 - 0.067 12.8 0.0 0.14 11.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein FMN_red PF03358.15 ETS77899.1 - 0.089 12.5 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 NADPH-dependent FMN reductase PBP_like PF12727.7 ETS77899.1 - 0.14 11.3 0.0 1.1 8.3 0.0 2.0 1 1 1 2 2 2 0 PBP superfamily domain FAD_binding_3 PF01494.19 ETS77900.1 - 8.4e-26 91.0 0.0 1.5e-25 90.2 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS77900.1 - 1e-07 31.9 0.1 0.0012 18.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS77900.1 - 4.3e-07 30.4 0.0 0.00014 22.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS77900.1 - 8.1e-07 28.5 0.0 0.011 15.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS77900.1 - 0.00016 21.8 0.0 0.00036 20.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain CoA_transf_3 PF02515.17 ETS77900.1 - 0.0036 16.5 0.1 0.0062 15.7 0.1 1.3 1 0 0 1 1 1 1 CoA-transferase family III FAD_binding_2 PF00890.24 ETS77900.1 - 0.0076 15.4 0.1 0.022 13.9 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 ETS77900.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 ETS77900.1 - 0.037 13.7 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 ETS77900.1 - 0.038 13.3 0.1 0.14 11.5 0.1 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 ETS77900.1 - 0.11 11.8 0.2 0.3 10.3 0.0 1.7 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 ETS77900.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 ETS77900.1 - 0.11 11.2 0.1 2.6 6.7 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein SE PF08491.10 ETS77900.1 - 0.13 11.3 0.0 11 5.0 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase 3HCDH_N PF02737.18 ETS77900.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zn_clus PF00172.18 ETS77901.1 - 8e-10 38.7 8.3 1.1e-09 38.2 8.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Histone_HNS PF00816.21 ETS77901.1 - 0.12 13.2 0.0 0.15 12.9 0.0 1.2 1 0 0 1 1 1 0 H-NS histone family Fungal_trans PF04082.18 ETS77902.1 - 2.6e-13 49.6 0.0 4.6e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3488 PF11992.8 ETS77903.1 - 0.11 11.4 0.0 0.24 10.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) DUF5402 PF17393.2 ETS77903.1 - 0.17 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5402) Pro-kuma_activ PF09286.11 ETS77904.1 - 5.4e-42 143.5 0.0 9e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ETS77904.1 - 0.032 13.5 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Subtilase family 2-Hacid_dh_C PF02826.19 ETS77905.1 - 1.2e-43 148.6 0.0 5.2e-42 143.2 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS77905.1 - 3.9e-07 29.8 0.0 8.6e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ETS77905.1 - 0.051 13.7 0.1 0.12 12.5 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.25 ETS77907.1 - 6.5e-19 68.2 0.0 2.1e-18 66.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS77907.1 - 2.8e-08 33.6 0.0 4.8e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS77907.1 - 5.1e-06 26.5 0.0 9.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.18 ETS77909.1 - 5.8e-12 45.2 1.2 1.4e-11 44.0 0.1 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain PROCT PF08084.11 ETS77909.1 - 0.093 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 PROCT (NUC072) domain FPP PF05911.11 ETS77914.1 - 0.0075 14.5 5.7 0.0098 14.1 5.7 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil SHE3 PF17078.5 ETS77914.1 - 0.01 15.5 6.8 0.016 14.9 6.8 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 ATG16 PF08614.11 ETS77914.1 - 0.011 16.0 9.7 0.011 16.0 9.7 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) GAS PF13851.6 ETS77914.1 - 0.08 12.3 6.7 0.21 10.9 6.7 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 ETS77914.1 - 0.081 12.0 3.0 0.13 11.3 3.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 ETS77914.1 - 0.13 12.9 2.6 0.27 11.9 1.1 2.1 1 1 1 2 2 2 0 Initiation control protein YabA V_ATPase_I PF01496.19 ETS77914.1 - 0.17 9.8 0.9 0.23 9.4 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Uso1_p115_C PF04871.13 ETS77914.1 - 0.19 12.1 9.9 0.38 11.1 9.9 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fez1 PF06818.15 ETS77914.1 - 0.27 11.7 7.4 0.44 11.0 6.9 1.6 1 1 0 1 1 1 0 Fez1 BRE1 PF08647.11 ETS77914.1 - 0.27 11.3 4.3 0.54 10.4 0.1 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Rootletin PF15035.6 ETS77914.1 - 0.45 10.5 7.9 0.81 9.7 7.9 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion PRKG1_interact PF15898.5 ETS77914.1 - 0.61 11.0 5.2 1.6 9.7 5.2 1.7 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain TMF_TATA_bd PF12325.8 ETS77914.1 - 1.4 9.2 7.9 3.1 8.0 7.9 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 ETS77914.1 - 1.5 8.9 11.0 2.7 8.1 11.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 ETS77914.1 - 3.5 7.7 6.3 19 5.3 3.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 ETS77914.1 - 3.7 7.3 6.4 5.7 6.7 3.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TRAF_BIRC3_bd PF16673.5 ETS77915.1 - 0.044 13.6 1.0 0.044 13.6 1.0 5.7 5 2 2 7 7 7 0 TNF receptor-associated factor BIRC3 binding domain Filament PF00038.21 ETS77915.1 - 0.45 10.0 60.2 0.95 9.0 12.7 4.3 1 1 1 3 3 3 0 Intermediate filament protein YejG PF13989.6 ETS77915.1 - 1.5 9.3 5.0 0.52 10.8 1.1 2.3 2 0 0 2 2 2 0 YejG-like protein TPR_MLP1_2 PF07926.12 ETS77915.1 - 3.9 7.6 69.3 0.032 14.3 18.5 5.3 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein p450 PF00067.22 ETS77916.1 - 5e-62 210.2 0.0 6.7e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_N_2 PF16884.5 ETS77917.1 - 2.3e-28 98.2 0.0 5.2e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 ETS77917.1 - 2.3e-16 60.0 0.0 3.5e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS77917.1 - 1.1e-06 29.7 0.0 2e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase P22_Cro PF14549.6 ETS77917.1 - 0.00029 20.6 0.0 0.00073 19.3 0.0 1.6 1 0 0 1 1 1 1 DNA-binding transcriptional regulator Cro zf-C2H2 PF00096.26 ETS77918.1 - 0.026 15.0 1.0 13 6.4 0.3 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_12 PF18658.1 ETS77918.1 - 1.8 8.2 5.9 1 9.0 0.5 2.7 3 0 0 3 3 3 0 Zinc-finger C2H2-type GMC_oxred_N PF00732.19 ETS77919.1 - 1.9e-59 201.5 0.0 5.1e-59 200.1 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS77919.1 - 1.4e-35 122.9 0.0 2.7e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS77919.1 - 4.3e-06 26.1 0.1 0.0032 16.6 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS77919.1 - 3.1e-05 24.1 0.1 8.2e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS77919.1 - 3.7e-05 23.5 0.6 0.00038 20.2 0.5 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ETS77919.1 - 0.00059 19.0 0.0 0.00089 18.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 ETS77919.1 - 0.0011 18.3 0.1 0.0027 17.0 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 ETS77919.1 - 0.0026 17.1 0.0 0.0056 16.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS77919.1 - 0.042 13.1 0.1 0.12 11.6 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ETS77919.1 - 0.073 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 ETS77919.1 - 0.091 11.5 0.3 0.2 10.3 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 ETS77919.1 - 0.15 11.1 0.3 0.54 9.3 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Peptidase_S10 PF00450.22 ETS77920.1 - 1.5e-84 284.8 1.7 3.6e-84 283.6 1.7 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase ABC1 PF03109.16 ETS77922.1 - 1.2e-22 80.3 0.0 3.6e-13 49.7 0.0 2.4 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 ETS77922.1 - 0.003 17.5 0.1 0.0087 16.0 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 ETS77922.1 - 0.066 12.8 0.0 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.25 ETS77922.1 - 0.11 11.9 0.0 0.41 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain Cyto_heme_lyase PF01265.17 ETS77923.1 - 2.9e-123 411.1 2.5 3.8e-123 410.7 2.5 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase HET PF06985.11 ETS77926.1 - 8.1e-34 117.1 0.1 1.6e-33 116.1 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.23 ETS77927.1 - 2.1e-22 79.4 2.1 2.1e-22 79.4 2.1 1.8 2 0 0 2 2 2 1 FAD binding domain ADH_N PF08240.12 ETS77928.1 - 8e-17 61.1 0.0 2.6e-16 59.4 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS77928.1 - 6.3e-08 32.7 0.0 1.5e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS77928.1 - 0.0013 18.3 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Sda PF08970.10 ETS77929.1 - 0.017 14.8 0.5 0.038 13.7 0.5 1.5 1 0 0 1 1 1 0 Sporulation inhibitor A CcdA PF07362.12 ETS77929.1 - 0.48 10.9 3.5 0.61 10.5 0.4 2.2 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA Ank_2 PF12796.7 ETS77930.1 - 2.4e-19 69.7 0.0 2.2e-15 57.0 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 ETS77930.1 - 9.9e-16 57.4 0.7 0.0013 19.1 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 ETS77930.1 - 3.8e-14 51.4 1.0 0.00014 22.0 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 ETS77930.1 - 1.3e-13 51.1 0.1 1.1e-06 29.0 0.0 4.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS77930.1 - 3.3e-10 40.0 1.6 0.0099 16.2 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Sugar_tr PF00083.24 ETS77931.1 - 7.7e-108 361.2 14.6 9.7e-108 360.9 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS77931.1 - 4.6e-25 88.3 17.1 4.6e-25 88.3 17.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF554 PF04474.12 ETS77931.1 - 1.1 8.6 7.9 0.058 12.8 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF554) PAP_assoc PF03828.19 ETS77932.1 - 5.9e-12 45.6 1.0 1.6e-11 44.2 0.0 2.3 3 0 0 3 3 3 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 ETS77932.1 - 3.6e-06 27.2 0.0 8.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain RCDG1 PF15725.5 ETS77933.1 - 0.47 10.9 3.2 1.1 9.7 3.2 1.5 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein zf_C2H2_10 PF18414.1 ETS77936.1 - 0.00062 19.2 0.1 0.0018 17.8 0.1 1.8 1 0 0 1 1 1 1 C2H2 type zinc-finger RCC1 PF00415.18 ETS77937.1 - 6.9e-59 196.3 9.4 2.5e-08 34.4 0.0 7.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ETS77937.1 - 2.8e-37 125.8 24.6 2.2e-09 36.9 0.6 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat CDC45 PF02724.14 ETS77937.1 - 0.069 11.4 4.8 0.11 10.8 4.8 1.4 1 0 0 1 1 1 0 CDC45-like protein SUKH-3 PF14433.6 ETS77937.1 - 0.13 12.8 0.1 9.3 6.7 0.0 3.1 3 0 0 3 3 3 0 SUKH-3 immunity protein DUF966 PF06136.13 ETS77937.1 - 0.26 10.9 8.9 0.38 10.4 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) BAF1_ABF1 PF04684.13 ETS77937.1 - 1.3 8.0 17.0 2 7.4 17.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 ETS77937.1 - 6.2 5.5 11.0 9.8 4.8 11.0 1.3 1 0 0 1 1 1 0 Presenilin Dehydratase_hem PF13816.6 ETS77939.1 - 1.5e-89 300.5 0.0 1.7e-89 300.3 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase HAD_2 PF13419.6 ETS77940.1 - 1.6e-09 38.1 0.0 6.8e-09 36.1 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETS77940.1 - 0.002 18.5 0.0 0.012 15.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TatD_DNase PF01026.21 ETS77941.1 - 4.8e-40 137.6 0.0 5.5e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase NACHT PF05729.12 ETS77942.1 - 5.4e-19 68.7 0.6 5e-18 65.6 0.0 2.8 3 1 0 3 3 3 1 NACHT domain HEAT_2 PF13646.6 ETS77942.1 - 3.1e-18 65.9 13.4 2.1e-06 28.0 1.1 5.4 3 2 1 4 4 4 3 HEAT repeats HEAT PF02985.22 ETS77942.1 - 4.3e-12 45.2 3.6 0.027 14.7 0.1 7.7 9 0 0 9 9 8 2 HEAT repeat NB-ARC PF00931.22 ETS77942.1 - 4e-10 39.3 0.0 1.1e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain NLRC4_HD2 PF17776.1 ETS77942.1 - 1.3e-06 28.9 2.6 2.7e-05 24.7 0.1 3.3 3 0 0 3 3 3 1 NLRC4 helical domain HD2 Adaptin_N PF01602.20 ETS77942.1 - 2.6e-05 23.0 1.4 5.6e-05 21.9 1.4 1.5 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_EZ PF13513.6 ETS77942.1 - 4.2e-05 23.9 11.0 0.0059 17.1 0.7 5.1 4 1 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.7 ETS77942.1 - 6e-05 23.1 4.8 0.0012 19.0 0.6 4.0 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 AAA_22 PF13401.6 ETS77942.1 - 7e-05 23.1 0.0 0.00083 19.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 ETS77942.1 - 0.00035 20.9 0.0 0.014 15.8 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_16 PF13191.6 ETS77942.1 - 0.00051 20.5 0.5 0.015 15.6 0.0 3.7 4 1 0 4 4 3 1 AAA ATPase domain AAA_18 PF13238.6 ETS77942.1 - 0.00086 19.9 0.0 0.0026 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain RTP1_C1 PF10363.9 ETS77942.1 - 0.003 17.7 1.5 0.11 12.7 0.1 3.5 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 ETS77942.1 - 0.0075 16.6 5.8 0.61 10.5 0.8 5.7 5 1 1 6 6 5 1 HEAT repeat associated with sister chromatid cohesion NTPase_1 PF03266.15 ETS77942.1 - 0.029 14.3 0.1 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 NTPase DUF676 PF05057.14 ETS77942.1 - 0.035 13.6 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PduV-EutP PF10662.9 ETS77942.1 - 0.091 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 ETS77942.1 - 0.11 13.0 0.0 0.78 10.2 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 ETS77942.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Roc PF08477.13 ETS77942.1 - 0.16 12.2 0.2 0.55 10.5 0.0 2.0 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_17 PF13207.6 ETS77942.1 - 0.28 11.6 1.2 4.7 7.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain TolA PF06519.11 ETS77942.1 - 1.3 9.2 3.0 71 3.7 0.0 4.3 4 2 2 6 6 6 0 TolA C-terminal CBM_20 PF00686.19 ETS77943.1 - 1e-24 86.2 0.1 2.1e-24 85.3 0.1 1.5 1 0 0 1 1 1 1 Starch binding domain LPMO_10 PF03067.15 ETS77943.1 - 1.5e-14 55.1 1.7 3e-14 54.1 1.7 1.5 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 ETS77943.1 - 0.033 14.1 3.2 1.1 9.1 0.6 3.2 2 1 1 3 3 3 0 Glycosyl hydrolase family 61 Oxysterol_BP PF01237.18 ETS77944.1 - 4.3e-56 190.3 0.1 1.7e-53 181.8 0.1 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein FlgD_ig PF13860.6 ETS77944.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 FlgD Ig-like domain Cnn_1N PF07989.11 ETS77945.1 - 0.01 16.0 0.6 0.026 14.7 0.6 1.7 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF1690 PF07956.11 ETS77945.1 - 0.02 15.3 4.1 0.024 15.0 1.7 2.3 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) ATG16 PF08614.11 ETS77945.1 - 0.58 10.3 8.0 0.49 10.6 5.7 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DMPK_coil PF08826.10 ETS77945.1 - 0.58 10.3 4.1 0.82 9.8 3.0 1.9 1 1 0 1 1 1 0 DMPK coiled coil domain like IBR PF01485.21 ETS77946.1 - 1.1e-14 54.4 22.9 2.7e-12 46.7 4.0 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain BcrAD_BadFG PF01869.20 ETS77946.1 - 0.033 13.7 0.3 0.08 12.4 0.3 1.7 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family RGS_DHEX PF18148.1 ETS77946.1 - 0.12 12.5 5.6 0.3 11.2 5.6 1.7 1 0 0 1 1 1 0 Regulator of G-protein signalling DHEX domain Hydantoinase_A PF01968.18 ETS77946.1 - 0.14 11.4 0.9 8.2 5.6 0.1 2.5 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase TAF4 PF05236.14 ETS77946.1 - 9.1 5.9 16.1 16 5.1 16.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Cellulase PF00150.18 ETS77947.1 - 1.5e-08 34.5 0.1 2.5e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HET PF06985.11 ETS77948.1 - 3.4e-29 102.1 0.2 5.5e-29 101.4 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RGI_lyase PF18370.1 ETS77949.1 - 5.3e-20 71.5 0.0 1.2e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Rhamnogalacturonan I lyases beta-sheet domain VCBS PF13517.6 ETS77949.1 - 1.1e-05 25.9 17.8 0.00055 20.5 4.7 5.0 4 2 2 6 6 6 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 ETS77949.1 - 0.017 15.2 21.4 0.23 11.6 1.2 3.7 3 0 0 3 3 3 0 FG-GAP repeat AtuA PF07287.11 ETS77950.1 - 6e-115 383.7 0.7 4.3e-114 380.9 0.7 1.9 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA ADH_zinc_N PF00107.26 ETS77950.1 - 0.1 12.6 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AMP-binding PF00501.28 ETS77951.1 - 2.3e-73 247.2 0.0 2.9e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS77951.1 - 7.7e-07 30.0 0.0 1.9e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AtuA PF07287.11 ETS77952.1 - 2.1e-129 431.3 0.3 2.6e-129 431.0 0.3 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA MaoC_dehydratas PF01575.19 ETS77953.1 - 1.2e-24 86.3 0.0 2e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ETS77953.1 - 2.4e-07 30.9 0.0 0.00015 21.9 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase ECH_1 PF00378.20 ETS77954.1 - 1.2e-33 116.4 0.0 3.3e-22 79.0 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ETS77954.1 - 6.9e-14 52.1 0.0 3e-07 30.3 0.0 3.0 1 1 2 3 3 3 3 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ETS77955.1 - 7.6e-59 199.0 0.0 9.8e-59 198.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ETS77955.1 - 4.9e-27 95.3 0.0 3e-26 92.7 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TRI12 PF06609.13 ETS77956.1 - 4.5e-73 246.7 23.4 5.8e-73 246.3 23.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ETS77956.1 - 5.2e-27 94.7 59.3 9.7e-26 90.5 52.7 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF3425 PF11905.8 ETS77957.1 - 3.1e-15 56.2 2.7 5.8e-15 55.4 2.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.15 ETS77957.1 - 0.00051 20.1 4.1 0.029 14.5 0.1 2.5 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 ETS77957.1 - 0.0064 16.6 8.5 0.096 12.8 1.6 2.7 2 1 1 3 3 3 2 bZIP transcription factor Lzipper-MIP1 PF14389.6 ETS77957.1 - 0.034 14.4 0.1 0.084 13.2 0.1 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Shugoshin_N PF07558.11 ETS77957.1 - 0.14 12.1 0.1 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.15 ETS77957.1 - 0.53 10.1 1.9 0.89 9.4 0.1 2.2 1 1 1 2 2 2 0 Septum formation initiator BBE PF08031.12 ETS77958.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like FAD_binding_4 PF01565.23 ETS77959.1 - 3.6e-25 88.3 1.8 5.7e-25 87.7 1.8 1.3 1 0 0 1 1 1 1 FAD binding domain zf-CCCH_2 PF14608.6 ETS77960.1 - 0.04 14.4 0.3 0.11 13.0 0.3 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Methyltransf_31 PF13847.6 ETS77961.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain P5CR_dimer PF14748.6 ETS77962.1 - 6e-36 122.8 0.7 1.1e-35 122.0 0.7 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 ETS77962.1 - 6.6e-20 71.5 0.4 1.5e-19 70.3 0.4 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ETS77962.1 - 0.0039 17.4 0.1 0.0088 16.2 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.17 ETS77962.1 - 0.01 14.8 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase NAD_Gly3P_dh_N PF01210.23 ETS77962.1 - 0.022 14.7 0.5 0.076 13.0 0.1 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 ETS77962.1 - 0.11 12.5 0.4 0.26 11.4 0.4 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HET PF06985.11 ETS77963.1 - 5.1e-08 33.4 12.3 5.4e-06 26.8 4.5 2.7 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) TRI12 PF06609.13 ETS77964.1 - 2.8e-34 118.5 28.9 3.4e-34 118.2 28.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ETS77964.1 - 2.5e-20 72.7 50.7 2.5e-20 72.7 50.7 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS77964.1 - 3.4e-08 32.8 40.5 1e-07 31.2 13.7 2.8 3 1 0 3 3 3 2 Sugar (and other) transporter Cation_ATPase_C PF00689.21 ETS77964.1 - 2.9 7.6 14.8 0.083 12.6 5.6 2.8 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus FAD_binding_3 PF01494.19 ETS77965.1 - 9.7e-25 87.5 0.7 4.6e-24 85.3 0.7 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ETS77965.1 - 1.8e-06 27.5 0.0 0.00066 19.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ETS77965.1 - 5e-06 26.1 0.2 0.0022 17.3 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 ETS77965.1 - 6.5e-05 22.7 0.6 0.0014 18.3 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS77965.1 - 6.8e-05 23.0 0.6 0.00024 21.2 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ETS77965.1 - 0.00017 20.4 0.1 0.11 11.1 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 ETS77965.1 - 0.00019 20.8 0.1 0.012 14.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS77965.1 - 0.028 14.9 0.0 0.067 13.8 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS77965.1 - 0.064 12.3 1.1 0.73 8.8 1.1 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 ETS77965.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Glyco_hydro_106 PF17132.4 ETS77966.1 - 9.8e-33 113.4 0.2 1.8e-30 105.9 1.0 2.1 1 1 0 2 2 2 2 alpha-L-rhamnosidase Glyco_hydro_2_N PF02837.18 ETS77966.1 - 0.00047 20.1 0.0 0.0015 18.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_transf_28 PF03033.20 ETS77967.1 - 9.1e-20 71.1 0.1 5e-19 68.7 0.1 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 ETS77967.1 - 0.0001 22.6 0.1 0.036 14.4 0.0 2.7 2 0 0 2 2 2 2 Autophagy-related protein C terminal domain UDPGT PF00201.18 ETS77967.1 - 0.00061 18.7 0.0 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ETS77967.1 - 0.002 18.1 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain HARP PF07443.13 ETS77967.1 - 0.1 12.3 0.2 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 HepA-related protein (HARP) RTA1 PF04479.13 ETS77968.1 - 4.3e-67 225.7 17.9 4.3e-67 225.7 17.9 1.5 2 0 0 2 2 2 1 RTA1 like protein Zn_clus PF00172.18 ETS77969.1 - 5.6e-07 29.6 1.3 1.3e-06 28.4 0.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS77969.1 - 0.018 13.9 0.5 0.037 12.9 0.5 1.6 1 1 0 1 1 1 0 Fungal specific transcription factor domain Bcl-2 PF00452.19 ETS77969.1 - 0.019 15.7 0.1 0.036 14.7 0.1 1.6 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family p450 PF00067.22 ETS77970.1 - 3.1e-35 121.8 0.1 3.8e-35 121.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 RTA1 PF04479.13 ETS77972.1 - 2.1e-65 220.2 13.6 2.9e-65 219.7 13.6 1.1 1 0 0 1 1 1 1 RTA1 like protein Bac_rhamnosid_C PF17390.2 ETS77973.1 - 6.9e-12 45.0 0.6 6.6e-10 38.6 0.0 2.9 3 0 0 3 3 3 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 ETS77973.1 - 7.5e-09 35.3 0.1 3e-07 30.0 0.1 2.3 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF1080 PF06439.11 ETS77973.1 - 0.0005 20.2 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Laminin_G_3 PF13385.6 ETS77973.1 - 0.0022 18.1 1.3 0.0047 17.1 0.1 2.2 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Ion_trans PF00520.31 ETS77974.1 - 8.3e-05 21.9 21.9 0.0002 20.7 21.9 1.6 1 1 0 1 1 1 1 Ion transport protein BPL_N PF09825.9 ETS77975.1 - 3.3e-144 480.6 0.0 4.1e-144 480.3 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 ETS77975.1 - 4.9e-23 81.5 0.0 7.7e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 ETS77975.1 - 0.0011 18.8 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain ThuA PF06283.11 ETS77975.1 - 0.012 15.8 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Trehalose utilisation Mgm101p PF06420.12 ETS77976.1 - 2.1e-84 281.2 0.0 2.6e-84 280.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 TB2_DP1_HVA22 PF03134.19 ETS77977.1 - 1.3e-25 89.1 8.5 2e-25 88.5 8.5 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family 7TM_GPCR_Srv PF10323.9 ETS77978.1 - 0.0007 19.0 0.1 0.0032 16.9 0.1 1.9 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF2371 PF10177.9 ETS77978.1 - 0.48 10.6 1.8 1.1 9.4 0.1 2.2 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF5411 PF17424.2 ETS77978.1 - 1.3 9.0 3.5 0.56 10.2 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5411) DUF4731 PF15875.5 ETS77978.1 - 6.3 7.1 5.7 9.1 6.6 0.2 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4731) Helo_like_N PF17111.5 ETS77979.1 - 1.6e-06 27.6 0.3 0.0039 16.6 0.0 2.5 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins Replicase PF03090.17 ETS77979.1 - 0.17 11.8 0.0 0.52 10.2 0.0 1.7 2 0 0 2 2 2 0 Replicase family DUF16 PF01519.16 ETS77979.1 - 0.23 11.9 2.0 6.1 7.4 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function DUF16 CAF1-p150_N PF15557.6 ETS77980.1 - 5.2 6.9 16.1 1.1 9.2 1.7 2.6 1 1 1 2 2 2 0 CAF1 complex subunit p150, region binding to PCNA Abhydrolase_3 PF07859.13 ETS77981.1 - 1e-33 117.0 0.0 1.7e-33 116.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS77981.1 - 3.5e-05 22.9 0.0 0.00029 19.9 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 ETS77981.1 - 0.0019 17.7 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 ETS77981.1 - 0.002 16.8 0.0 0.0031 16.2 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 ETS77981.1 - 0.39 10.2 0.0 0.39 10.2 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family RAP1 PF07218.11 ETS77982.1 - 0.046 12.0 2.1 0.062 11.6 2.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Apt1 PF10351.9 ETS77982.1 - 0.2 10.5 5.7 0.32 9.8 5.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.9 ETS77982.1 - 0.4 10.3 22.3 0.99 9.0 20.2 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Lactamase_B PF00753.27 ETS77982.1 - 0.69 9.9 6.3 0.2 11.7 1.8 2.5 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily QWRF PF04484.12 ETS77982.1 - 1.4 8.6 9.3 0.28 10.9 5.4 1.7 2 0 0 2 2 2 0 QWRF family PAP1 PF08601.10 ETS77982.1 - 1.7 8.3 7.1 3 7.5 7.1 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.9 ETS77982.1 - 2.9 6.3 8.7 0.44 9.0 4.5 1.6 2 0 0 2 2 2 0 Macoilin family Dioxygenase_C PF00775.21 ETS77983.1 - 2.9e-07 30.1 0.1 4.7e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase FMO-like PF00743.19 ETS77984.1 - 4.3e-53 180.5 0.0 5.6e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ETS77984.1 - 6.7e-14 51.8 0.0 9.4e-12 44.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS77984.1 - 1.1e-11 44.6 0.0 5.3e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS77984.1 - 1e-08 34.7 0.0 8.9e-07 28.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ETS77984.1 - 2.9e-06 27.4 0.0 7.5e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS77984.1 - 6e-06 26.3 0.0 0.00053 20.0 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 ETS77984.1 - 0.00086 19.8 0.0 0.81 10.3 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ETS77984.1 - 0.0022 18.0 0.0 0.38 10.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 ETS77984.1 - 0.016 14.5 0.0 0.037 13.3 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ETS77984.1 - 0.071 12.3 0.1 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 ETS77984.1 - 0.074 13.5 0.0 11 6.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 ETS77984.1 - 0.099 12.8 0.0 0.38 10.9 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 ETS77984.1 - 0.1 12.2 0.0 1.8 8.1 0.0 2.6 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 ETS77984.1 - 0.14 11.5 0.0 18 4.7 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 ETS77984.1 - 0.22 10.2 0.0 1.5 7.5 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein RNase_H PF00075.24 ETS77985.1 - 2.7e-09 37.4 0.0 1.9e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 RNase H Fungal_trans_2 PF11951.8 ETS77986.1 - 0.00032 19.6 3.3 0.0031 16.4 0.3 2.4 2 1 0 2 2 2 2 Fungal specific transcription factor domain GST_N PF02798.20 ETS77987.1 - 1.2e-14 54.4 0.0 3e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ETS77987.1 - 9.9e-12 45.1 0.0 1.9e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ETS77987.1 - 3.7e-11 43.1 0.0 6.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ETS77987.1 - 6.3e-11 42.4 0.0 1.7e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ETS77987.1 - 9.3e-09 35.4 0.0 1.5e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ETS77987.1 - 0.0005 20.0 0.1 0.0019 18.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain p450 PF00067.22 ETS77988.1 - 2e-52 178.5 0.0 2.5e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 ETS77989.1 - 2.7e-31 108.8 32.6 3.5e-31 108.4 32.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4017 PF13209.6 ETS77989.1 - 0.014 15.3 2.2 0.016 15.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) Jagunal PF07086.12 ETS77989.1 - 0.64 10.1 8.0 32 4.5 1.0 3.9 4 1 1 5 5 5 0 Jagunal, ER re-organisation during oogenesis SpoVAB PF13782.6 ETS77989.1 - 6.5 7.1 8.0 0.6 10.4 2.3 2.2 2 0 0 2 2 2 0 Stage V sporulation protein AB HTH_psq PF05225.16 ETS77990.1 - 8.6e-19 67.0 0.2 8.2e-09 35.1 0.0 2.3 2 0 0 2 2 2 2 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.16 ETS77990.1 - 1.6e-09 37.6 0.1 3.1e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_1 PF01527.20 ETS77990.1 - 0.00055 20.2 0.5 0.016 15.5 0.0 2.7 2 1 1 3 3 3 1 Transposase HTH_28 PF13518.6 ETS77990.1 - 0.072 13.2 0.1 0.23 11.6 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain NMT1 PF09084.11 ETS77991.1 - 3e-11 43.7 0.2 5.1e-11 42.9 0.2 1.5 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_3 PF16868.5 ETS77991.1 - 0.00011 21.8 0.1 0.00022 20.7 0.0 1.5 2 0 0 2 2 2 1 NMT1-like family SBP_bac_3 PF00497.20 ETS77991.1 - 0.00016 21.2 0.2 0.00027 20.4 0.2 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 ETS77991.1 - 0.004 16.8 0.5 0.0055 16.3 0.5 1.4 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Rax2 PF12768.7 ETS77992.1 - 0.00025 20.6 0.0 0.0004 19.9 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Pam16 PF03656.13 ETS77993.1 - 6.7e-32 110.2 0.9 7.7e-32 110.0 0.9 1.0 1 0 0 1 1 1 1 Pam16 DUF2884 PF11101.8 ETS77993.1 - 0.046 13.2 0.2 0.071 12.6 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) Apolipoprotein PF01442.18 ETS77993.1 - 0.14 12.0 0.3 0.14 12.0 0.3 2.2 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Yip1 PF04893.17 ETS77994.1 - 1.1e-06 28.5 14.9 0.007 16.1 0.3 2.4 2 1 0 2 2 2 2 Yip1 domain Glyco_hydro_61 PF03443.14 ETS77995.1 - 1.9e-59 201.1 0.3 2.3e-59 200.8 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Chal_sti_synt_C PF02797.15 ETS77996.1 - 7e-24 84.5 0.0 1.3e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 ETS77996.1 - 3e-21 75.9 0.5 4.7e-21 75.2 0.5 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.12 ETS77996.1 - 5.7e-06 25.8 0.0 8.3e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 ETS77996.1 - 7.7e-06 26.0 0.0 0.00012 22.2 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal p450 PF00067.22 ETS77997.1 - 9.1e-23 80.7 0.0 4.2e-22 78.5 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Cad PF03596.13 ETS77998.1 - 4.9e-24 85.3 8.9 7e-24 84.8 8.9 1.2 1 0 0 1 1 1 1 Cadmium resistance transporter DUF5134 PF17197.4 ETS77998.1 - 0.0058 16.6 1.3 0.0098 15.8 0.1 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF5134) DUF3278 PF11683.8 ETS77998.1 - 3.8 7.6 8.9 0.65 10.1 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Methyltransf_25 PF13649.6 ETS77999.1 - 9.8e-05 23.0 0.0 0.00022 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS77999.1 - 0.00082 19.2 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS77999.1 - 0.01 16.6 0.1 0.019 15.7 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF1996 PF09362.10 ETS78000.1 - 7.2e-72 242.2 3.7 1e-71 241.6 3.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Fe-ADH PF00465.19 ETS78001.1 - 1.1e-61 208.7 0.0 1.3e-61 208.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ETS78001.1 - 4.8e-05 23.2 0.0 0.014 15.1 0.0 2.3 2 1 0 2 2 2 2 Iron-containing alcohol dehydrogenase RRM_1 PF00076.22 ETS78002.1 - 4.2e-09 36.1 0.1 7.3e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ETS78002.1 - 0.0015 18.5 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 ETS78002.1 - 0.051 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 RNA binding motif DUF2046 PF09755.9 ETS78004.1 - 0.0031 16.8 0.5 0.027 13.7 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) FlaC_arch PF05377.11 ETS78004.1 - 0.14 12.5 0.3 0.35 11.3 0.3 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) CASP_C PF08172.12 ETS78004.1 - 0.14 11.4 7.2 0.14 11.5 2.6 2.4 2 1 0 2 2 2 0 CASP C terminal LtuB PF17455.2 ETS78004.1 - 0.17 12.5 0.1 0.3 11.7 0.1 1.4 1 0 0 1 1 1 0 Late transcription unit B Striatin PF08232.12 ETS78004.1 - 0.28 11.8 0.0 0.28 11.8 0.0 2.4 2 1 0 2 2 2 0 Striatin family GreA_GreB_N PF03449.15 ETS78004.1 - 0.31 11.2 5.5 0.095 12.9 1.9 1.9 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Csm1_N PF18504.1 ETS78004.1 - 0.5 10.7 6.4 0.083 13.2 1.4 2.0 2 0 0 2 2 2 0 Csm1 N-terminal domain DivIC PF04977.15 ETS78004.1 - 5.6 6.8 5.4 0.84 9.5 1.1 1.7 2 0 0 2 2 2 0 Septum formation initiator p450 PF00067.22 ETS78006.1 - 3.6e-67 227.1 0.0 4.6e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 ETS78008.1 - 5.6e-34 117.6 26.1 5.6e-34 117.6 26.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 ETS78009.1 - 7.5e-62 208.9 0.0 9.9e-62 208.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS78009.1 - 1.1e-06 27.8 0.0 1.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ETS78009.1 - 0.00015 21.3 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 ETS78009.1 - 0.004 16.1 0.0 0.014 14.2 0.0 1.8 3 0 0 3 3 3 1 Steryl acetyl hydrolase Glyco_hydro81C PF17652.1 ETS78010.1 - 1.5e-165 550.7 8.5 1.9e-165 550.3 8.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 ETS78010.1 - 8.7e-117 389.9 0.5 1.2e-116 389.4 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Stn1 PF10451.9 ETS78011.1 - 6.2e-19 68.0 1.5 3.4e-09 36.0 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 ETS78011.1 - 0.00082 19.3 0.0 0.0023 17.9 0.0 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 ETS78011.1 - 0.036 13.9 0.2 0.18 11.6 0.2 2.0 1 1 0 1 1 1 0 RecQ-mediated genome instability protein 2 Spem1 PF15670.5 ETS78011.1 - 0.12 12.0 4.3 0.2 11.2 4.3 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 DDHD PF02862.17 ETS78011.1 - 0.93 9.6 4.7 1.3 9.1 4.7 1.2 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 ETS78011.1 - 3.8 6.2 4.2 4.6 5.9 4.2 1.2 1 0 0 1 1 1 0 Presenilin PAN_1 PF00024.26 ETS78013.1 - 0.00013 21.9 1.5 0.00021 21.2 1.5 1.3 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 ETS78013.1 - 0.003 17.4 2.2 0.0063 16.4 2.2 1.5 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 ETS78013.1 - 0.084 12.7 0.7 0.14 12.0 0.7 1.3 1 0 0 1 1 1 0 PAN-like domain GCFC PF07842.12 ETS78013.1 - 0.098 12.3 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein DnaJ PF00226.31 ETS78014.1 - 8.3e-22 77.1 0.9 8.3e-22 77.1 0.9 2.4 2 0 0 2 2 2 1 DnaJ domain Sulfotransfer_2 PF03567.14 ETS78014.1 - 0.016 15.2 0.2 0.021 14.7 0.2 1.2 1 0 0 1 1 1 0 Sulfotransferase family IDEAL PF08858.10 ETS78014.1 - 0.038 13.7 0.1 0.14 12.0 0.1 2.0 1 0 0 1 1 1 0 IDEAL domain TarH PF02203.15 ETS78014.1 - 6.7 6.6 7.1 1.7 8.5 1.4 2.3 1 1 2 3 3 3 0 Tar ligand binding domain homologue Inv-AAD PF18785.1 ETS78015.1 - 8e-62 206.8 0.0 9.4e-62 206.6 0.0 1.1 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 ETS78015.1 - 4.8e-14 52.1 0.0 6.7e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 ETS78015.1 - 0.0046 16.9 0.0 0.0055 16.6 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain MafB19-deam PF14437.6 ETS78015.1 - 0.03 14.1 0.0 0.041 13.6 0.0 1.4 1 1 0 1 1 1 0 MafB19-like deaminase Cellulase PF00150.18 ETS78016.1 - 4.7e-17 62.3 3.4 6.5e-17 61.9 3.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 ETS78016.1 - 4.6e-05 22.7 0.0 0.00056 19.1 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 ETS78016.1 - 0.0053 16.1 0.0 0.037 13.4 0.0 2.0 2 0 0 2 2 2 1 Beta-galactosidase FAD_binding_4 PF01565.23 ETS78017.1 - 3.5e-27 94.8 0.2 5.4e-27 94.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS78017.1 - 0.024 14.7 0.1 0.069 13.3 0.1 1.7 1 0 0 1 1 1 0 Berberine and berberine like p450 PF00067.22 ETS78018.1 - 4.9e-57 193.7 0.0 7e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Alpha-L-AF_C PF06964.12 ETS78019.1 - 1.9e-26 93.2 0.0 2.8e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_79n PF03662.14 ETS78019.1 - 0.081 11.8 0.1 0.44 9.4 0.1 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 79, N-terminal domain Glyco_hydro_44 PF12891.7 ETS78019.1 - 0.14 12.1 0.8 0.31 11.0 0.7 1.6 1 1 0 1 1 1 0 Glycoside hydrolase family 44 LapD_MoxY_N PF16448.5 ETS78019.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 LapD/MoxY periplasmic domain Sugar_tr PF00083.24 ETS78020.1 - 5.3e-75 253.0 26.6 6.1e-75 252.8 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS78020.1 - 7.5e-24 84.3 26.5 7e-21 74.5 26.7 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF1290 PF06947.12 ETS78020.1 - 4.5 7.4 7.7 0.86 9.7 2.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1290) zf-RING_2 PF13639.6 ETS78023.1 - 8.3e-11 42.0 3.5 1.3e-10 41.5 3.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ETS78023.1 - 5.3e-07 29.8 4.0 1.5e-06 28.4 4.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ETS78023.1 - 1.7e-05 24.8 1.0 3.1e-05 23.9 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ETS78023.1 - 3e-05 24.0 3.6 4.2e-05 23.5 2.3 2.0 2 1 1 3 3 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ETS78023.1 - 3.8e-05 23.4 4.4 8e-05 22.4 4.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS78023.1 - 0.00021 21.0 2.1 0.00061 19.6 2.2 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ETS78023.1 - 0.00043 20.1 2.1 0.0007 19.4 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 ETS78023.1 - 0.00089 19.0 3.9 0.0056 16.5 0.2 2.7 2 1 0 2 2 2 1 Rad50 zinc hook motif Prok-RING_4 PF14447.6 ETS78023.1 - 0.0012 18.6 3.8 0.15 12.0 0.7 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 ETS78023.1 - 0.019 15.2 1.6 6.6 7.1 0.2 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-UDP PF14569.6 ETS78023.1 - 0.024 14.7 2.3 0.078 13.1 0.4 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_5 PF14634.6 ETS78023.1 - 0.03 14.3 0.9 0.056 13.4 0.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 ETS78023.1 - 0.046 13.5 4.9 0.45 10.3 5.5 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 ETS78023.1 - 0.071 12.9 0.8 0.17 11.7 0.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger DUF305 PF03713.13 ETS78023.1 - 0.082 13.0 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF305) FANCL_C PF11793.8 ETS78023.1 - 0.19 11.9 1.8 4.9 7.4 1.8 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain hNIFK_binding PF12196.8 ETS78023.1 - 0.37 10.3 4.0 1.4 8.5 1.0 2.9 3 0 0 3 3 3 0 FHA Ki67 binding domain of hNIFK Zn-C2H2_12 PF18112.1 ETS78023.1 - 0.51 10.8 3.2 9.3 6.8 0.2 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C3HC4_4 PF15227.6 ETS78023.1 - 2.6 8.3 5.5 5.5 7.2 5.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_5 PF17121.5 ETS78023.1 - 7 6.6 6.7 54 3.8 6.8 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Acetyltransf_10 PF13673.7 ETS78024.1 - 3.9e-08 33.3 0.0 6.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETS78024.1 - 5.7e-06 26.4 0.0 0.23 11.6 0.0 3.1 2 1 1 3 3 3 3 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS78024.1 - 2.9e-05 24.3 0.0 6.7e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 ETS78024.1 - 8.4e-05 22.6 0.0 0.00039 20.5 0.0 2.0 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 ETS78024.1 - 0.00028 21.3 0.0 0.00062 20.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS78024.1 - 0.15 12.0 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein FAD_binding_4 PF01565.23 ETS78025.1 - 6e-22 77.9 2.9 1.2e-21 76.9 2.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS78025.1 - 4.7e-10 39.4 0.6 1.1e-09 38.3 0.6 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF3600 PF12207.8 ETS78025.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) Cytokin-bind PF09265.10 ETS78025.1 - 0.19 11.1 0.2 0.37 10.1 0.2 1.4 1 1 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding ketoacyl-synt PF00109.26 ETS78026.1 - 1.7e-72 244.0 0.1 1.4e-71 241.0 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ETS78026.1 - 1.1e-31 109.3 0.6 2.6e-31 108.1 0.6 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 ETS78026.1 - 1.6e-26 92.0 0.1 1.7e-25 88.7 0.1 2.7 3 0 0 3 3 3 1 Helix-turn-helix domain Acyl_transf_1 PF00698.21 ETS78026.1 - 5.1e-25 88.6 0.8 9.8e-22 77.8 0.1 2.3 2 0 0 2 2 2 2 Acyl transferase domain PS-DH PF14765.6 ETS78026.1 - 1e-20 74.2 0.0 1.6e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 ETS78026.1 - 6.9e-16 58.8 0.0 2.2e-15 57.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 ETS78026.1 - 1.1e-15 58.0 2.0 1.5e-14 54.4 0.1 2.6 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Abhydrolase_3 PF07859.13 ETS78026.1 - 1.4e-13 51.2 0.0 6.3e-13 49.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_23 PF13489.6 ETS78026.1 - 9.8e-13 48.3 0.0 2.8e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 ETS78026.1 - 2.1e-12 47.2 3.2 6.5e-12 45.6 3.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 ETS78026.1 - 2.6e-09 37.7 0.0 9.5e-09 35.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ETS78026.1 - 7.1e-09 36.1 0.0 7.4e-08 32.8 0.0 2.8 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 ETS78026.1 - 2.2e-08 35.0 3.0 1.8e-05 25.4 3.3 3.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ETS78026.1 - 7.5e-08 32.1 0.0 0.00026 20.5 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Methyltransf_31 PF13847.6 ETS78026.1 - 5.3e-07 29.6 0.0 1.3e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 ETS78026.1 - 8.8e-06 25.3 0.1 4.1e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.12 ETS78026.1 - 2.3e-05 25.0 0.0 0.00013 22.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Thioesterase PF00975.20 ETS78026.1 - 0.0034 17.5 0.0 0.018 15.2 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain COesterase PF00135.28 ETS78026.1 - 0.0034 16.3 0.0 0.0068 15.3 0.0 1.4 1 0 0 1 1 1 1 Carboxylesterase family Ubie_methyltran PF01209.18 ETS78026.1 - 0.046 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DLH PF01738.18 ETS78026.1 - 0.052 13.1 0.0 15 5.1 0.0 3.1 3 0 0 3 3 3 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 ETS78026.1 - 0.071 12.4 0.0 0.35 10.1 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 ACP_syn_III PF08545.10 ETS78026.1 - 2.2 8.2 6.4 0.3 11.0 0.1 2.6 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Acetyltransf_1 PF00583.25 ETS78027.1 - 2.2e-07 31.1 0.0 3.7e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS78027.1 - 0.00021 21.2 0.0 0.00033 20.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETS78027.1 - 0.0011 19.1 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS78027.1 - 0.0064 16.9 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ETS78027.1 - 0.045 13.9 0.0 0.098 12.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MFS_1 PF07690.16 ETS78028.1 - 1.9e-42 145.5 51.5 2.8e-39 135.1 53.9 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Piwi PF02171.17 ETS78029.1 - 6.6e-69 232.4 0.0 1e-68 231.8 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 ETS78029.1 - 1.2e-11 45.3 0.0 2.3e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 ETS78029.1 - 2.1e-11 44.0 0.0 6.3e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoL1 PF08699.10 ETS78029.1 - 2.7e-10 39.7 0.1 8e-10 38.2 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 ETS78029.1 - 1.3e-05 25.0 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 ETS78029.1 - 5.7e-05 23.3 0.1 0.00021 21.5 0.1 2.0 2 0 0 2 2 2 1 Mid domain of argonaute Flavokinase PF01687.17 ETS78030.1 - 2.3e-35 121.2 0.0 2.8e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Zn_clus PF00172.18 ETS78031.1 - 0.0036 17.4 8.6 0.0084 16.2 8.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 ETS78031.1 - 0.0063 16.5 0.0 0.023 14.7 0.0 1.9 2 0 0 2 2 2 1 PAS fold Cellulase PF00150.18 ETS78032.1 - 2.1e-11 43.8 2.2 4.1e-11 42.8 2.2 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) EphA2_TM PF14575.6 ETS78032.1 - 0.00095 20.0 0.8 0.0029 18.5 0.0 2.2 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF4064 PF13273.6 ETS78032.1 - 0.062 13.6 0.2 0.12 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF3792 PF12670.7 ETS78032.1 - 0.079 13.1 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) RCR PF12273.8 ETS78032.1 - 0.14 12.8 0.3 0.14 12.8 0.3 2.1 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red MASE4 PF17158.4 ETS78032.1 - 0.21 10.8 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 Membrane-associated sensor, integral membrane domain Insulin_TMD PF17870.1 ETS78032.1 - 0.29 11.2 3.2 0.61 10.2 3.2 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Transket_pyr PF02779.24 ETS78033.1 - 1.4e-44 151.9 0.0 2.5e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ETS78033.1 - 1.1e-34 119.0 0.2 3.1e-34 117.5 0.1 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 ETS78033.1 - 0.00035 20.8 0.0 0.00067 19.9 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II F-actin_cap_A PF01267.17 ETS78034.1 - 8.7e-98 327.0 0.0 9.8e-98 326.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit ACAS_N PF16177.5 ETS78034.1 - 0.012 15.5 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus Cyt-b5 PF00173.28 ETS78035.1 - 4e-23 81.3 0.1 5.2e-23 81.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF347 PF03988.12 ETS78035.1 - 0.019 15.1 0.1 0.026 14.7 0.1 1.2 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) U62_UL91 PF17442.2 ETS78035.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Functional domain of U62 and UL91 proteins TFA2_Winged_2 PF18121.1 ETS78036.1 - 6.9e-20 70.5 0.5 1.8e-19 69.2 0.2 1.9 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 ETS78036.1 - 7.5e-09 35.8 0.2 2.7e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 TFIIE beta subunit core domain DSBA PF01323.20 ETS78037.1 - 1.1e-08 35.1 0.0 5.9e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 DSBA-like thioredoxin domain CUE PF02845.16 ETS78037.1 - 0.097 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 CUE domain Thioredoxin_4 PF13462.6 ETS78037.1 - 0.19 11.9 0.0 1.8 8.7 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin zf-C2H2 PF00096.26 ETS78038.1 - 2.7e-22 77.9 25.5 1.8e-05 24.9 0.2 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ETS78038.1 - 5.6e-17 61.3 30.8 1.7e-06 28.2 1.2 5.4 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 ETS78038.1 - 3.1e-12 46.2 22.6 0.0042 17.8 1.3 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ETS78038.1 - 2.9e-06 27.4 0.1 4.7 7.6 0.0 4.5 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 ETS78038.1 - 0.0019 17.9 8.7 0.02 14.6 0.8 3.3 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-met PF12874.7 ETS78038.1 - 0.0086 16.4 13.1 2.8 8.5 0.0 5.0 6 0 0 6 6 6 2 Zinc-finger of C2H2 type FOXP-CC PF16159.5 ETS78038.1 - 0.11 13.1 2.4 12 6.6 0.2 3.0 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 ETS78038.1 - 0.12 12.3 6.6 4.5 7.3 0.2 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 ETS78038.1 - 0.26 10.9 8.5 1.2 8.8 0.2 3.4 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 ETS78038.1 - 0.79 9.9 9.0 20 5.4 0.6 3.4 1 1 2 3 3 3 0 Zinc ribbon domain DUF2256 PF10013.9 ETS78038.1 - 1 9.6 7.0 23 5.2 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-LYAR PF08790.11 ETS78038.1 - 3.3 7.7 4.2 6.3 6.8 0.1 3.2 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger DZR PF12773.7 ETS78038.1 - 4.9 7.3 8.9 1.5e+02 2.5 8.9 2.4 1 1 0 1 1 1 0 Double zinc ribbon XPA_N PF01286.18 ETS78038.1 - 6.7 6.8 8.6 0.85 9.7 0.5 3.1 4 0 0 4 4 4 0 XPA protein N-terminal Ogr_Delta PF04606.12 ETS78038.1 - 9.8 6.3 10.1 11 6.0 0.8 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DHBP_synthase PF00926.19 ETS78039.1 - 6.1e-82 273.8 0.0 7.1e-82 273.6 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Methyltransf_23 PF13489.6 ETS78040.1 - 3.6e-21 75.7 0.0 6.6e-21 74.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS78040.1 - 5e-20 71.9 0.0 8.6e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS78040.1 - 9.6e-17 61.2 0.0 1.3e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS78040.1 - 1.9e-16 60.5 0.0 3.7e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS78040.1 - 7.3e-15 55.5 0.0 1.2e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS78040.1 - 4.8e-08 32.6 0.0 6.6e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 ETS78040.1 - 4.1e-07 29.7 0.0 5.7e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 ETS78040.1 - 8.1e-05 21.7 0.0 0.00012 21.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 ETS78040.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 ETS78040.1 - 0.0025 17.4 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 ETS78040.1 - 0.0027 17.3 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) AA_permease PF00324.21 ETS78041.1 - 7.6e-103 344.7 44.6 9.4e-103 344.3 44.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS78041.1 - 5.3e-25 88.1 52.0 7.9e-25 87.5 51.7 1.4 1 1 0 1 1 1 1 Amino acid permease NCE101 PF11654.8 ETS78041.1 - 0.075 12.8 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Non-classical export protein 1 Pox_A_type_inc PF04508.12 ETS78042.1 - 0.049 13.5 0.8 0.17 11.8 0.8 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF373 PF04123.13 ETS78042.1 - 0.093 12.2 2.0 0.13 11.6 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Hexapep PF00132.24 ETS78045.1 - 8.4e-09 34.8 6.1 3.5e-06 26.5 1.5 3.0 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ETS78045.1 - 9.9e-05 22.0 6.3 0.37 10.6 0.0 3.7 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Complex1_51K PF01512.17 ETS78046.1 - 1.4e-47 161.4 0.0 2.3e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 ETS78046.1 - 2.7e-29 101.1 1.5 3.1e-29 100.9 0.2 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 ETS78046.1 - 2e-09 37.2 0.0 5.2e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 SLBB domain zf-CHY PF05495.12 ETS78049.1 - 1.2e-10 41.7 9.8 1.2e-10 41.7 9.8 3.3 2 1 1 3 3 3 1 CHY zinc finger RWD PF05773.22 ETS78049.1 - 0.00032 21.0 0.2 0.0074 16.6 0.0 2.5 2 0 0 2 2 2 1 RWD domain zf-trcl PF13451.6 ETS78049.1 - 0.59 10.1 0.0 0.59 10.1 0.0 3.8 5 0 0 5 5 5 0 Probable zinc-ribbon domain GMC_oxred_N PF00732.19 ETS78050.1 - 1.2e-62 211.9 0.0 1.9e-62 211.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS78050.1 - 5.7e-26 91.8 0.0 1.1e-25 90.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS78050.1 - 1.4e-07 31.0 0.0 0.011 14.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ETS78050.1 - 1.8e-05 24.2 0.0 0.0062 15.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS78050.1 - 6.8e-05 23.0 0.1 0.00021 21.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS78050.1 - 0.00018 21.2 0.2 0.021 14.5 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 ETS78050.1 - 0.0027 17.0 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 ETS78050.1 - 0.0083 16.7 0.0 0.081 13.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS78050.1 - 0.013 14.8 0.0 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS78050.1 - 0.034 14.1 0.0 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ETS78050.1 - 0.046 12.8 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Tannase PF07519.11 ETS78051.1 - 1.2e-119 400.3 5.1 1.5e-119 400.0 5.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 ETS78051.1 - 0.028 13.7 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Glyco_hydro_28 PF00295.17 ETS78052.1 - 7.6e-29 100.8 0.2 1.1e-28 100.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 ETS78052.1 - 0.0042 16.9 7.4 0.0048 16.8 1.5 2.9 1 1 1 2 2 2 1 Pectate lyase superfamily protein Beta_helix PF13229.6 ETS78052.1 - 0.022 14.6 9.8 0.037 13.9 9.6 1.5 1 1 0 1 1 1 0 Right handed beta helix region Tannase PF07519.11 ETS78053.1 - 2.6e-98 330.0 0.5 3.1e-98 329.7 0.5 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 ETS78053.1 - 4.8e-05 22.7 0.0 0.0038 16.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ETS78053.1 - 0.00014 21.4 0.0 0.069 12.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ETS78053.1 - 0.0039 16.9 0.0 0.0084 15.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 ETS78053.1 - 0.1 12.2 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Zn_clus PF00172.18 ETS78054.1 - 1.1e-05 25.4 1.9 2.5e-05 24.3 1.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS78054.1 - 4.3e-05 22.5 1.2 6.2e-05 22.0 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Opy2 PF09463.10 ETS78054.1 - 0.06 13.7 1.3 0.19 12.0 1.3 1.9 1 0 0 1 1 1 0 Opy2 protein RTA1 PF04479.13 ETS78055.1 - 2.3e-59 200.5 12.0 2.3e-59 200.5 12.0 1.7 1 1 1 2 2 2 1 RTA1 like protein DUF1129 PF06570.11 ETS78055.1 - 5.2 6.5 8.9 6.4 6.2 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) HET PF06985.11 ETS78056.1 - 2e-28 99.6 0.0 4.3e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ESR1_C PF12743.7 ETS78056.1 - 0.78 9.6 2.6 2 8.3 2.6 1.7 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal Amidase PF01425.21 ETS78057.1 - 7.5e-49 166.9 0.2 2.2e-45 155.5 0.2 2.1 1 1 1 2 2 2 2 Amidase Tannase PF07519.11 ETS78058.1 - 3.2e-39 135.1 0.1 7.5e-32 110.8 0.0 2.2 1 1 1 2 2 2 2 Tannase and feruloyl esterase Cellulase PF00150.18 ETS78058.1 - 2.4e-16 60.0 3.0 4.5e-16 59.1 3.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ank_2 PF12796.7 ETS78059.1 - 8.1e-81 266.7 0.0 2.9e-12 47.0 0.0 11.6 4 2 7 12 12 12 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS78059.1 - 1.6e-70 232.6 11.2 9.3e-10 38.9 0.1 14.7 10 2 3 14 14 14 12 Ankyrin repeats (many copies) Ank PF00023.30 ETS78059.1 - 1.4e-54 180.2 16.2 4e-05 23.9 0.0 17.6 17 1 1 18 18 18 10 Ankyrin repeat Ank_3 PF13606.6 ETS78059.1 - 1.3e-51 166.5 11.9 0.0005 20.3 0.0 18.8 18 0 0 18 18 18 11 Ankyrin repeat Ank_5 PF13857.6 ETS78059.1 - 9.5e-43 143.7 18.8 4.5e-06 26.8 0.2 15.8 10 3 6 16 16 16 12 Ankyrin repeats (many copies) C1_2 PF03107.16 ETS78059.1 - 0.062 13.6 7.1 0.15 12.4 7.1 1.6 1 0 0 1 1 1 0 C1 domain Peptidase_S9 PF00326.21 ETS78059.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family ZZ PF00569.17 ETS78059.1 - 0.15 11.9 13.9 0.044 13.6 9.9 2.1 2 0 0 2 2 2 0 Zinc finger, ZZ type Peptidase_S8 PF00082.22 ETS78061.1 - 2.1e-20 73.2 0.4 4e-20 72.3 0.4 1.4 1 0 0 1 1 1 1 Subtilase family Ank_4 PF13637.6 ETS78061.1 - 2.4e-08 34.3 0.2 0.0043 17.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS78061.1 - 6.9e-08 33.0 1.7 0.0046 17.5 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ETS78061.1 - 3.3e-06 27.3 0.6 0.2 12.2 0.0 4.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 ETS78061.1 - 6.1e-05 23.1 0.4 2.3 9.1 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 ETS78061.1 - 0.00056 20.2 0.2 2.9 8.3 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) DUF3295 PF11702.8 ETS78062.1 - 1.4e-151 506.3 37.8 1.8e-151 505.9 37.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 ETS78062.1 - 5.8e-12 45.2 2.1 1.1e-11 44.3 2.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) VHS PF00790.19 ETS78064.1 - 2.5e-25 89.0 0.0 1.4e-24 86.6 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 ETS78064.1 - 9.9e-07 29.0 0.3 2.4e-06 27.8 0.3 1.6 1 0 0 1 1 1 1 GAT domain Ion_trans_2 PF07885.16 ETS78066.1 - 2.4e-31 107.5 28.8 1.3e-17 63.6 4.8 3.3 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.31 ETS78066.1 - 0.18 11.0 14.1 0.1 11.8 0.4 2.7 2 1 0 2 2 2 0 Ion transport protein Abhydrolase_3 PF07859.13 ETS78067.1 - 0.00046 20.1 0.0 0.00094 19.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold pPIWI_RE_Z PF18155.1 ETS78067.1 - 0.0099 15.8 0.2 0.04 13.8 0.1 2.0 1 1 1 2 2 2 1 pPIWI RE three-gene island domain Z Semialdhyde_dhC PF02774.18 ETS78068.1 - 6.4e-40 137.2 0.0 8.4e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 ETS78068.1 - 4e-31 108.0 0.0 1.7e-30 105.9 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 ETS78068.1 - 0.0044 17.2 0.0 0.0085 16.2 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 ETS78068.1 - 0.018 15.8 0.0 0.046 14.4 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mito_fiss_reg PF05308.11 ETS78069.1 - 0.059 13.5 6.6 0.083 13.0 6.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3439 PF11921.8 ETS78069.1 - 0.56 10.2 11.3 0.77 9.7 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 ETS78069.1 - 6.4 4.6 7.1 8.1 4.3 7.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RskA PF10099.9 ETS78069.1 - 8.8 6.6 20.7 52 4.1 20.7 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Zn-ribbon_8 PF09723.10 ETS78070.1 - 0.026 14.6 1.1 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_4 PF14570.6 ETS78070.1 - 0.1 12.4 1.4 3.2 7.6 0.1 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF4796 PF16044.5 ETS78070.1 - 0.24 11.0 0.7 0.24 11.0 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Glyco_hydro_76 PF03663.14 ETS78071.1 - 3.3e-154 513.8 14.6 4.1e-154 513.5 14.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 ETS78071.1 - 1.1 8.3 8.6 25 3.8 7.0 2.9 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Synaptobrevin PF00957.21 ETS78072.1 - 4.7e-28 96.8 1.1 5.1e-28 96.7 1.1 1.0 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 ETS78072.1 - 0.085 13.5 0.0 0.086 13.5 0.0 1.1 1 0 0 1 1 1 0 AT-hook-containing transcription factor EMP24_GP25L PF01105.24 ETS78072.1 - 0.19 11.7 0.1 0.21 11.5 0.1 1.0 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD NAT PF04768.13 ETS78073.1 - 3.5e-49 166.7 0.2 6.9e-49 165.8 0.2 1.5 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 ETS78073.1 - 3.7e-31 108.6 0.0 4.1e-30 105.2 0.0 2.4 2 0 0 2 2 2 1 Amino acid kinase family Semialdhyde_dh PF01118.24 ETS78073.1 - 6.3e-31 107.3 0.0 1.7e-30 105.9 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 ETS78073.1 - 0.057 13.5 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GTP_EFTU PF00009.27 ETS78074.1 - 1e-45 155.7 0.0 1.7e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 ETS78074.1 - 8.2e-27 93.3 0.9 1.7e-26 92.3 0.9 1.5 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 ETS78074.1 - 9e-09 35.4 0.0 0.00011 22.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 ETS78074.1 - 2.3e-07 31.1 0.1 9.3e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 ETS78074.1 - 2.6e-07 30.9 0.1 1.7e-06 28.3 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Roc PF08477.13 ETS78074.1 - 0.00039 20.6 0.0 0.047 13.9 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ETS78074.1 - 0.0099 15.3 0.0 0.72 9.3 0.0 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 ETS78074.1 - 0.027 13.9 1.0 4 6.8 0.0 2.6 2 1 1 3 3 3 0 ADP-ribosylation factor family cobW PF02492.19 ETS78074.1 - 0.03 13.9 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 ETS78074.1 - 0.15 11.6 0.0 2.8 7.4 0.0 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B EF-hand_7 PF13499.6 ETS78075.1 - 9.3e-16 58.1 1.2 2.1e-08 34.5 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ETS78075.1 - 1.3e-12 46.3 9.8 1.8e-05 24.0 0.6 3.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 ETS78075.1 - 6.7e-12 44.3 7.7 3.1e-05 23.6 0.8 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 ETS78075.1 - 1.1e-10 41.2 3.1 1.6e-06 27.8 0.5 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 ETS78075.1 - 0.00023 20.5 7.9 0.054 13.0 0.4 4.1 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 ETS78075.1 - 0.018 15.4 0.2 0.23 11.8 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.7 ETS78075.1 - 0.17 11.9 1.8 0.54 10.2 0.4 2.0 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Nup96 PF12110.8 ETS78076.1 - 2.3e-99 332.2 0.5 3.3e-99 331.7 0.5 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 ETS78076.1 - 7.4e-49 165.7 0.0 1.4e-48 164.8 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 ETS78076.1 - 3e-27 95.3 257.7 2.4e-10 41.1 32.7 12.5 4 2 10 14 14 14 9 Nucleoporin FG repeat region Cpn60_TCP1 PF00118.24 ETS78077.1 - 1.2e-156 522.2 6.1 1.3e-156 522.1 6.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.12 ETS78077.1 - 0.048 13.5 0.2 0.47 10.3 0.1 2.5 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein Enolase_N PF03952.16 ETS78077.1 - 0.24 11.6 2.2 34 4.6 0.1 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain DUF3176 PF11374.8 ETS78079.1 - 2e-25 89.1 2.6 2e-25 89.1 2.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) NrsF PF06532.11 ETS78079.1 - 2.8 7.6 13.2 0.086 12.6 1.5 2.8 3 0 0 3 3 3 0 Negative regulator of sigma F Glyco_hydro_43 PF04616.14 ETS78081.1 - 4.7e-35 121.3 9.0 6.8e-35 120.8 9.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ETS78081.1 - 5.8e-22 78.4 0.1 8.5e-22 77.9 0.1 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain RcnB PF11776.8 ETS78081.1 - 0.079 13.0 0.2 0.27 11.3 0.2 1.9 1 0 0 1 1 1 0 Nickel/cobalt transporter regulator KR PF08659.10 ETS78082.1 - 3e-59 200.0 0.2 6.9e-59 198.8 0.2 1.7 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.26 ETS78082.1 - 2.3e-55 187.9 0.0 1.6e-54 185.2 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 ETS78082.1 - 7.2e-49 167.0 0.0 1.2e-48 166.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 ETS78082.1 - 2.3e-42 145.3 0.0 2.3e-42 145.3 0.0 1.7 2 0 0 2 2 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 ETS78082.1 - 5.8e-35 119.9 0.0 1.2e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ETS78082.1 - 3.7e-18 66.1 0.0 9.7e-18 64.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 ETS78082.1 - 4.5e-16 60.1 0.0 2.7e-15 57.6 0.0 2.5 2 0 0 2 2 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 ETS78082.1 - 3.3e-14 53.3 0.1 4.2e-12 46.5 0.1 2.8 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 ETS78082.1 - 5.6e-13 48.8 0.1 5.3e-12 45.6 0.0 2.5 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N PF00107.26 ETS78082.1 - 9.1e-13 48.3 0.4 3.3e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 ETS78082.1 - 1.5e-11 44.4 0.0 6e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS78082.1 - 3.3e-10 39.9 0.0 9.7e-10 38.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 ETS78082.1 - 9.3e-10 38.7 0.0 3.2e-09 37.0 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 ETS78082.1 - 6.6e-09 36.4 0.1 3.8e-08 33.9 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS78082.1 - 8.3e-09 36.0 0.0 2.3e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 ETS78082.1 - 4.7e-07 29.6 0.0 1.1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 ETS78082.1 - 6.5e-05 22.4 0.0 0.00017 21.0 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family SAT PF16073.5 ETS78082.1 - 0.00054 19.8 0.2 0.0016 18.2 0.2 1.8 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_28 PF02636.17 ETS78082.1 - 0.0011 18.7 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase ADH_N PF08240.12 ETS78082.1 - 0.0039 17.0 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.25 ETS78082.1 - 0.012 15.1 1.1 0.055 12.9 0.2 2.3 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Methyltransf_16 PF10294.9 ETS78082.1 - 0.031 14.0 0.0 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_33 PF10017.9 ETS78082.1 - 0.087 12.0 0.0 0.47 9.5 0.0 2.0 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent MFS_1 PF07690.16 ETS78083.1 - 1.8e-34 119.2 47.9 1.2e-33 116.6 46.8 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS78083.1 - 9.5e-12 44.5 17.0 9.5e-12 44.5 17.0 3.2 2 2 0 3 3 3 2 Sugar (and other) transporter p450 PF00067.22 ETS78085.1 - 3.2e-53 181.1 0.0 3.8e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HECT PF00632.25 ETS78086.1 - 6.8e-66 222.8 0.0 9.2e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 ETS78086.1 - 2.5e-20 72.5 1.3 5.6e-20 71.3 1.3 1.6 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-C2H2_2 PF12756.7 ETS78087.1 - 1e-35 122.1 8.5 1.3e-29 102.5 1.4 3.7 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 ETS78087.1 - 8.5e-10 38.7 10.3 2.6e-05 24.4 0.5 4.0 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ETS78087.1 - 4.3e-05 23.8 0.6 4.3e-05 23.8 0.6 3.2 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 ETS78087.1 - 0.00035 21.2 11.6 0.42 11.6 0.2 5.3 5 0 0 5 5 5 2 C2H2-type zinc finger zf_Hakai PF18408.1 ETS78087.1 - 0.036 13.8 0.8 0.094 12.4 0.8 1.7 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain ZZ PF00569.17 ETS78087.1 - 0.13 12.1 2.0 6.1 6.7 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, ZZ type zf-C2H2 PF00096.26 ETS78087.1 - 0.18 12.3 16.2 5.1 7.8 0.5 4.8 4 1 1 5 5 5 0 Zinc finger, C2H2 type zf-TFIIIC PF12660.7 ETS78087.1 - 0.21 11.6 1.2 3.3 7.7 1.2 2.7 1 1 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex PARM PF17061.5 ETS78087.1 - 1.3 9.1 8.8 3.1 7.8 8.8 1.8 1 1 0 1 1 1 0 PARM p450 PF00067.22 ETS78088.1 - 6.4e-40 137.3 0.0 3.9e-39 134.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 ETS78089.1 - 2.1e-08 33.9 0.1 8e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ETS78089.1 - 0.00023 21.0 0.1 0.00085 19.1 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ETS78089.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 F-box VHS PF00790.19 ETS78090.1 - 1.1e-40 138.8 2.8 3.3e-40 137.2 0.1 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 ETS78090.1 - 3.5e-15 55.9 4.3 6.2e-15 55.1 4.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 ETS78090.1 - 9.4e-07 28.3 12.4 0.0024 17.6 1.5 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 ETS78090.1 - 6.7e-05 23.1 0.0 0.00022 21.4 0.0 2.0 1 0 0 1 1 1 1 GAT domain BAF1_ABF1 PF04684.13 ETS78090.1 - 0.49 9.4 6.0 0.79 8.7 6.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Fer4_2 PF12797.7 ETS78090.1 - 7.2 6.9 8.0 13 6.1 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain UCH PF00443.29 ETS78091.1 - 1.7e-27 96.5 0.0 2.6e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ETS78091.1 - 1.7e-08 34.4 0.0 2.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 ETS78091.1 - 2.9e-06 27.8 0.0 8.1e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain USP8_dimer PF08969.11 ETS78091.1 - 0.0075 16.4 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain AMP-binding PF00501.28 ETS78092.1 - 6.3e-90 301.8 0.0 8.4e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme tRNA_edit PF04073.15 ETS78092.1 - 0.014 15.5 0.0 6.7 6.8 0.0 2.6 1 1 1 2 2 2 0 Aminoacyl-tRNA editing domain AMP-binding_C PF13193.6 ETS78092.1 - 0.12 13.4 0.0 0.47 11.5 0.0 2.1 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Cyclin_N PF00134.23 ETS78093.1 - 2.3e-15 56.4 0.0 3.5e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ETS78093.1 - 2.6e-08 34.4 0.1 1.6e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 Cyclin PRIMA1 PF16101.5 ETS78093.1 - 1.7 8.7 7.5 0.23 11.5 3.0 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 SRP40_C PF05022.12 ETS78094.1 - 5.3e-23 81.7 1.7 5.3e-23 81.7 1.7 3.1 2 0 0 2 2 2 1 SRP40, C-terminal domain Sclerostin PF05463.11 ETS78094.1 - 1.1 8.9 0.0 1.1 8.9 0.0 3.1 3 0 0 3 3 3 0 Sclerostin (SOST) BrnT_toxin PF04365.13 ETS78095.1 - 0.012 16.0 0.8 6.6 7.1 0.0 2.7 3 0 0 3 3 3 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system RDD PF06271.12 ETS78095.1 - 0.44 10.7 10.1 0.099 12.8 3.7 2.2 2 0 0 2 2 2 0 RDD family DHHC PF01529.20 ETS78095.1 - 2.9 8.0 7.1 4.5 7.4 1.5 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase PEX11 PF05648.14 ETS78096.1 - 2.4e-19 69.7 0.9 2.7e-09 36.8 0.1 3.8 3 1 0 3 3 3 3 Peroxisomal biogenesis factor 11 (PEX11) His_Phos_1 PF00300.22 ETS78097.1 - 1.3e-20 73.9 0.1 1.4e-19 70.5 0.0 2.0 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) Serendipity_A PF05482.12 ETS78097.1 - 0.04 12.6 0.0 0.052 12.2 0.0 1.2 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) Coat_F PF07875.12 ETS78097.1 - 0.083 13.1 0.1 0.4 10.9 0.0 2.1 2 0 0 2 2 2 0 Coat F domain Suf PF05843.14 ETS78098.1 - 2.2 8.2 6.6 2.8 7.9 6.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RNA_pol_3_Rpc31 PF11705.8 ETS78099.1 - 0.016 15.5 22.1 0.018 15.3 22.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 ETS78099.1 - 0.56 9.5 19.2 0.6 9.4 19.2 1.2 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 ETS78099.1 - 3.7 7.0 10.4 3.7 7.1 10.4 1.1 1 0 0 1 1 1 0 PPP4R2 PTPA PF03095.15 ETS78100.1 - 9.7e-111 370.0 0.0 1.1e-110 369.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein CENP-F_leu_zip PF10473.9 ETS78102.1 - 0.0015 18.6 23.7 0.0015 18.6 23.7 12.2 1 1 10 11 11 11 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ntox28 PF15605.6 ETS78102.1 - 0.013 15.8 0.5 0.013 15.8 0.5 13.3 4 1 8 14 14 14 0 Bacterial toxin 28 Fib_alpha PF08702.10 ETS78102.1 - 0.029 14.6 0.1 0.029 14.6 0.1 10.7 3 2 6 11 11 11 0 Fibrinogen alpha/beta chain family FAM184 PF15665.5 ETS78102.1 - 0.082 12.7 248.1 0.17 11.7 15.7 11.7 2 1 9 11 11 11 0 Family with sequence similarity 184, A and B ArfGap PF01412.18 ETS78103.1 - 4.6e-40 136.3 0.7 6.8e-40 135.8 0.7 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf partial_CstF PF15861.5 ETS78103.1 - 0.083 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain Synaptobrevin PF00957.21 ETS78104.1 - 0.03 14.1 0.6 0.15 11.9 0.3 1.9 1 1 1 2 2 2 0 Synaptobrevin Phage_holin_2_4 PF16082.5 ETS78104.1 - 0.045 13.5 0.1 0.09 12.5 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Ysc84 PF04366.12 ETS78105.1 - 1.6e-41 141.0 0.1 2.7e-41 140.3 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 ETS78105.1 - 5e-12 45.2 0.1 1.9e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 ETS78105.1 - 2.6e-10 39.8 0.0 4.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ETS78105.1 - 1.1e-08 34.8 0.0 2.2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain p450 PF00067.22 ETS78106.1 - 3.2e-70 237.2 0.0 4.1e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Kinesin PF00225.23 ETS78106.1 - 8.1e-59 199.2 0.0 1.3e-58 198.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ETS78106.1 - 3.1e-12 46.7 0.0 8e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 ETS78106.1 - 0.027 14.8 0.3 0.073 13.4 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ETS78106.1 - 0.086 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1996 PF09362.10 ETS78107.1 - 6.5e-65 219.4 1.7 8.1e-65 219.1 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) adh_short_C2 PF13561.6 ETS78111.1 - 5e-09 36.1 0.2 5.5e-09 35.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS78111.1 - 3.8e-08 33.0 0.1 4.5e-08 32.8 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase CPT PF07931.12 ETS78113.1 - 0.12 12.2 0.5 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Myb_DNA-bind_2 PF08914.11 ETS78114.1 - 6.8e-34 115.9 0.9 2.5e-17 62.8 0.2 2.7 2 0 0 2 2 2 2 Rap1 Myb domain Rap1_C PF11626.8 ETS78114.1 - 1.4e-21 76.3 0.1 3.6e-20 71.8 0.1 2.6 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain BRCT_2 PF16589.5 ETS78114.1 - 2.2e-12 47.2 0.0 4.5e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain ARID PF01388.21 ETS78114.1 - 6.9e-11 42.7 0.1 2.6e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Rap1-DNA-bind PF09197.10 ETS78114.1 - 7.6e-09 36.1 1.4 0.001 19.6 0.2 3.1 2 1 0 2 2 2 2 Rap1, DNA-binding Myb_DNA-binding PF00249.31 ETS78114.1 - 7e-05 22.9 0.1 0.0082 16.3 0.0 3.6 4 0 0 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ETS78114.1 - 0.0096 16.2 5.9 0.046 14.0 0.0 3.8 5 0 0 5 5 5 1 Myb-like DNA-binding domain DHHC PF01529.20 ETS78115.1 - 5.2e-33 114.0 6.0 5.2e-33 114.0 6.0 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase MMR_HSR1 PF01926.23 ETS78116.1 - 3e-13 49.9 0.0 8e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETS78116.1 - 1.2e-06 28.5 0.2 0.00038 20.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 ETS78116.1 - 6.4e-06 25.8 0.0 2.9e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 ETS78116.1 - 0.016 14.8 0.0 0.31 10.5 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 ETS78116.1 - 0.029 14.2 0.0 3.3 7.4 0.0 2.4 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 ETS78116.1 - 0.086 13.2 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Dynamin_N PF00350.23 ETS78116.1 - 0.7 9.9 0.0 0.7 9.9 0.0 3.5 3 1 0 3 3 3 0 Dynamin family Complex1_LYR_2 PF13233.6 ETS78117.1 - 2.6e-24 85.7 0.7 3.1e-24 85.5 0.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 ETS78117.1 - 0.028 14.5 0.2 0.04 14.0 0.2 1.3 1 0 0 1 1 1 0 Complex 1 protein (LYR family) p450 PF00067.22 ETS78118.1 - 1.5e-69 235.0 0.0 2e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 ETS78119.1 - 3e-27 95.8 0.0 1.3e-26 93.7 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_3_C PF01915.22 ETS78120.1 - 3.4e-47 161.0 0.0 7e-47 160.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ETS78120.1 - 7.6e-22 77.2 0.0 1.4e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 ETS78120.1 - 3e-20 72.8 0.1 6.5e-20 71.7 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain DXP_synthase_N PF13292.6 ETS78120.1 - 0.25 10.5 0.4 0.46 9.6 0.4 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Sugar_tr PF00083.24 ETS78121.1 - 2e-57 195.1 20.8 2.3e-57 194.9 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS78121.1 - 9.3e-22 77.4 37.4 9.3e-22 77.4 37.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS78121.1 - 0.57 8.7 29.1 0.14 10.6 12.6 3.7 3 1 1 4 4 4 0 MFS/sugar transport protein MCR_gamma PF02240.16 ETS78122.1 - 0.084 12.1 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase gamma subunit FMN_red PF03358.15 ETS78123.1 - 6e-13 48.8 0.0 1.2e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ETS78123.1 - 9.1e-05 22.3 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin-like fold MFS_1 PF07690.16 ETS78124.1 - 3e-41 141.5 29.4 3e-41 141.5 29.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS78124.1 - 3.4e-05 22.9 9.8 3.4e-05 22.9 9.8 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ETS78124.1 - 5e-05 21.9 1.8 9e-05 21.1 1.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2140 PF09911.9 ETS78124.1 - 0.056 13.0 0.2 0.1 12.1 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) FA_desaturase PF00487.24 ETS78124.1 - 7.7 6.3 18.6 0.94 9.3 1.0 3.3 2 1 0 3 3 3 0 Fatty acid desaturase Aha1_N PF09229.11 ETS78125.1 - 3.2e-40 137.5 0.5 4.7e-40 137.0 0.5 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 ETS78125.1 - 1.3e-19 70.6 0.9 2.4e-19 69.8 0.9 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF4448 PF14610.6 ETS78126.1 - 2.6e-27 95.8 0.0 3.9e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4395 PF14340.6 ETS78126.1 - 0.017 15.5 0.1 0.056 13.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) DUF3377 PF11857.8 ETS78126.1 - 0.018 14.9 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Ribosomal_S12 PF17487.2 ETS78126.1 - 0.038 14.7 0.5 0.094 13.5 0.5 1.6 1 0 0 1 1 1 0 Ribosomal protein S12 TMEM154 PF15102.6 ETS78126.1 - 0.079 12.9 0.1 0.079 12.9 0.1 1.9 2 0 0 2 2 2 0 TMEM154 protein family RCR PF12273.8 ETS78126.1 - 0.18 12.4 2.9 0.2 12.3 0.1 2.4 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Dioxygenase_C PF00775.21 ETS78127.1 - 2.7e-09 36.7 0.2 8.1e-09 35.2 0.2 1.8 1 1 0 1 1 1 1 Dioxygenase Peptidase_M24 PF00557.24 ETS78128.1 - 1.1e-47 162.5 0.0 1.3e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 ETS78128.1 - 5.5e-20 71.4 9.4 5.5e-20 71.4 9.4 1.7 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 ETS78128.1 - 0.0016 18.5 8.1 0.0016 18.5 8.1 2.0 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 ETS78128.1 - 0.35 10.8 3.4 0.78 9.7 3.4 1.7 1 0 0 1 1 1 0 HIT zinc finger LPMO_10 PF03067.15 ETS78129.1 - 1.1e-06 29.5 0.5 1.4e-06 29.1 0.5 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_43 PF04616.14 ETS78130.1 - 0.0036 16.7 1.0 0.006 15.9 1.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 ETS78130.1 - 0.008 15.8 0.1 0.022 14.3 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain DUF2456 PF10445.9 ETS78131.1 - 2.4e-09 37.1 1.4 2.4e-09 37.1 1.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) p450 PF00067.22 ETS78132.1 - 4.6e-37 127.8 0.0 5.7e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS78133.1 - 2e-28 99.4 0.0 4.1e-26 91.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 ETS78134.1 - 2e-24 86.2 0.0 3.1e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MBOAT_2 PF13813.6 ETS78135.1 - 1.2e-12 48.0 0.5 4.8e-12 46.0 0.5 2.0 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family ERG4_ERG24 PF01222.17 ETS78136.1 - 1.8e-85 287.3 7.2 2.2e-85 287.0 7.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 ETS78136.1 - 1.9e-05 24.3 0.6 5.5e-05 22.8 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 ETS78136.1 - 0.0026 18.2 0.0 0.0087 16.5 0.0 1.9 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 ETS78137.1 - 4.2e-141 470.6 5.5 5.1e-141 470.3 5.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 ETS78137.1 - 0.00084 18.9 0.2 0.002 17.7 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF1035 PF06281.12 ETS78138.1 - 0.95 9.5 4.9 9.6 6.3 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1035) DUF4064 PF13273.6 ETS78138.1 - 2.7 8.3 8.3 71 3.8 0.0 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) Pectinesterase PF01095.19 ETS78140.1 - 1.7e-45 155.0 8.4 2.1e-45 154.7 8.4 1.1 1 0 0 1 1 1 1 Pectinesterase DUF3869 PF12985.7 ETS78140.1 - 6.6 7.2 7.6 1.5 9.3 2.5 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3869) Iso_dh PF00180.20 ETS78141.1 - 1.2e-86 291.1 0.0 1.3e-86 290.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Abhydrolase_1 PF00561.20 ETS78142.1 - 2e-20 73.6 0.0 2.6e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS78142.1 - 2.1e-11 44.8 0.0 2.4e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS78142.1 - 1.1e-05 24.9 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 ETS78142.1 - 0.089 11.4 0.0 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Thr_synth_N PF14821.6 ETS78142.1 - 0.096 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Threonine synthase N terminus Fungal_trans PF04082.18 ETS78144.1 - 2.3e-22 79.3 3.8 2.3e-22 79.3 3.8 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain PRANC PF09372.10 ETS78144.1 - 0.016 15.5 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 PRANC domain FAD_binding_2 PF00890.24 ETS78145.1 - 6.2e-95 318.7 0.1 7.1e-95 318.5 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ETS78145.1 - 2.4e-06 27.7 0.6 7.1e-06 26.2 0.1 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ETS78145.1 - 9.8e-06 25.0 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS78145.1 - 1.6e-05 24.7 1.8 0.00021 21.0 1.7 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS78145.1 - 4.5e-05 22.8 0.1 0.00025 20.4 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ETS78145.1 - 0.00013 21.5 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ETS78145.1 - 0.00013 21.2 1.6 0.00016 20.9 0.0 1.9 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 ETS78145.1 - 0.00088 18.6 0.1 0.0053 16.0 0.1 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 ETS78145.1 - 0.0011 17.7 1.7 0.0035 16.1 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 ETS78145.1 - 0.077 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS78145.1 - 0.21 10.6 0.1 0.31 10.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TauD PF02668.16 ETS78146.1 - 6.1e-41 141.0 0.1 8.8e-41 140.5 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_3 PF01494.19 ETS78147.1 - 7.4e-16 58.3 2.1 2e-14 53.6 2.1 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ETS78147.1 - 0.0076 16.5 0.0 0.078 13.2 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ETS78147.1 - 0.14 11.1 0.0 0.5 9.4 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Glyco_hydro_61 PF03443.14 ETS78148.1 - 3.2e-56 190.5 0.5 3.9e-56 190.3 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Abhydrolase_3 PF07859.13 ETS78150.1 - 2.6e-43 148.3 0.0 3.2e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 ETS78150.1 - 3e-05 23.7 0.0 0.012 15.2 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 ETS78150.1 - 0.00012 21.6 0.0 0.0013 18.2 0.1 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 ETS78150.1 - 0.002 18.8 0.3 0.0029 18.3 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 ETS78150.1 - 0.002 17.7 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 ETS78150.1 - 0.0034 17.2 0.0 0.0055 16.5 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF2974 PF11187.8 ETS78150.1 - 0.0097 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Esterase_phd PF10503.9 ETS78150.1 - 0.011 15.2 0.1 0.034 13.6 0.1 1.8 2 0 0 2 2 2 0 Esterase PHB depolymerase AXE1 PF05448.12 ETS78150.1 - 0.013 14.2 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.25 ETS78150.1 - 0.025 14.4 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.11 ETS78150.1 - 0.03 14.2 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal COesterase PF00135.28 ETS78150.1 - 0.034 13.0 0.0 0.12 11.3 0.0 1.7 1 1 0 1 1 1 0 Carboxylesterase family Thioesterase PF00975.20 ETS78150.1 - 0.18 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 ETS78150.1 - 0.21 11.2 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF3244 PF11589.8 ETS78151.1 - 2.6 8.2 5.0 0.67 10.1 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3244) Pyr_redox_2 PF07992.14 ETS78152.1 - 2.7e-29 102.3 0.0 4.1e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS78152.1 - 1.6e-08 35.0 0.0 4.1e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS78152.1 - 0.033 13.4 0.0 0.51 9.5 0.0 2.4 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS78152.1 - 0.047 12.8 0.0 0.082 12.0 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) ADH_N PF08240.12 ETS78153.1 - 5e-26 90.7 0.4 1.3e-25 89.3 0.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS78153.1 - 1e-21 77.3 0.3 1.2e-20 73.8 0.1 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS78153.1 - 0.0019 19.3 0.0 0.0031 18.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ETS78153.1 - 0.0041 16.4 0.2 0.0064 15.8 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF4453 PF14627.6 ETS78153.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4453) CbiA PF01656.23 ETS78153.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain adh_short PF00106.25 ETS78153.1 - 0.16 11.4 0.2 0.31 10.5 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Preseq_ALAS PF09029.10 ETS78154.1 - 9.8e-05 22.8 5.6 0.023 15.2 1.0 2.4 1 1 1 2 2 2 2 5-aminolevulinate synthase presequence PDR_CDR PF06422.12 ETS78154.1 - 5 7.1 5.3 16 5.5 0.0 3.6 5 0 0 5 5 5 0 CDR ABC transporter MFS_1 PF07690.16 ETS78155.1 - 1.7e-34 119.3 35.5 1.7e-34 119.3 35.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS78155.1 - 6.1e-14 51.7 28.4 6.2e-12 45.1 11.1 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter COX4_pro_2 PF07835.12 ETS78155.1 - 0.032 14.3 2.2 0.4 10.8 0.0 3.4 3 0 0 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV NDUFA12 PF05071.16 ETS78155.1 - 0.056 14.3 0.1 0.11 13.3 0.1 1.4 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 BT1 PF03092.16 ETS78155.1 - 0.15 10.2 12.4 0.011 14.0 1.5 2.8 3 0 0 3 3 3 0 BT1 family CHORD PF04968.12 ETS78156.1 - 0.15 12.8 9.6 0.96 10.2 9.6 2.2 1 1 0 1 1 1 0 CHORD Zn_clus PF00172.18 ETS78157.1 - 2.8e-10 40.2 11.4 5.7e-10 39.2 11.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS78157.1 - 1.6e-05 24.1 0.1 3.2e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pectate_lyase PF03211.13 ETS78158.1 - 2.9e-62 209.8 13.1 1.5e-48 165.0 11.2 2.5 2 1 1 3 3 3 2 Pectate lyase MSP1_C PF07462.11 ETS78158.1 - 0.23 10.1 6.2 0.33 9.6 6.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Pro_CA PF00484.19 ETS78159.1 - 2.1e-14 54.1 0.2 8.7e-14 52.1 0.2 1.8 1 1 0 1 1 1 1 Carbonic anhydrase DUF1100 PF06500.11 ETS78160.1 - 6e-12 45.1 0.0 7.3e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.20 ETS78160.1 - 3.2e-05 23.7 0.0 7.4e-05 22.5 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 ETS78160.1 - 0.00012 21.8 0.0 0.00066 19.4 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 ETS78160.1 - 0.00034 20.5 0.0 0.00067 19.5 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 ETS78160.1 - 0.0081 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 ETS78160.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.4 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 ETS78160.1 - 0.015 14.6 0.0 0.031 13.5 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS78160.1 - 0.018 15.7 0.1 0.032 14.8 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family MIT PF04212.18 ETS78160.1 - 0.062 13.4 0.4 0.12 12.4 0.4 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Wzy_C_2 PF11846.8 ETS78160.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal DLH PF01738.18 ETS78160.1 - 0.11 12.0 0.1 0.37 10.3 0.0 1.7 1 1 1 2 2 2 0 Dienelactone hydrolase family Glyco_transf_25 PF01755.17 ETS78161.1 - 3.8e-05 23.6 0.0 0.00077 19.4 0.0 2.7 2 1 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) adh_short_C2 PF13561.6 ETS78162.1 - 1.2e-52 178.9 1.2 1.4e-52 178.6 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS78162.1 - 5.1e-41 140.3 1.0 6.5e-41 140.0 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS78162.1 - 3.7e-08 33.5 0.2 4.9e-08 33.1 0.2 1.3 1 1 0 1 1 1 1 KR domain YjeF_N PF03853.15 ETS78162.1 - 0.054 13.4 0.1 0.094 12.6 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus ZNRF_3_ecto PF18212.1 ETS78162.1 - 0.062 13.3 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 ZNRF-3 Ectodomain Eno-Rase_NADH_b PF12242.8 ETS78162.1 - 0.072 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.15 ETS78162.1 - 0.08 12.8 0.4 0.15 11.9 0.4 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.21 ETS78162.1 - 0.14 11.6 0.1 0.28 10.6 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3716 PF12511.8 ETS78163.1 - 0.0038 17.2 7.8 0.0072 16.3 7.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF747 PF05346.11 ETS78164.1 - 4.8e-121 404.1 3.5 6.3e-121 403.7 3.5 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF4834 PF16118.5 ETS78164.1 - 0.029 15.3 1.2 51 4.9 0.0 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Herpes_LMP1 PF05297.11 ETS78164.1 - 0.3 10.2 0.0 0.3 10.2 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Cutinase PF01083.22 ETS78165.1 - 1e-43 149.4 0.7 1.2e-43 149.1 0.7 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 ETS78165.1 - 0.0045 16.6 0.4 0.01 15.4 0.1 1.6 2 0 0 2 2 2 1 PE-PPE domain DUF3089 PF11288.8 ETS78165.1 - 0.0065 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) VirJ PF06057.11 ETS78165.1 - 0.013 15.4 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.16 ETS78165.1 - 0.029 14.2 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 ETS78165.1 - 0.064 13.9 0.4 0.11 13.1 0.4 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS78165.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pkinase PF00069.25 ETS78166.1 - 1.5e-09 37.6 1.2 0.00052 19.5 0.4 3.4 3 1 2 5 5 5 2 Protein kinase domain APH PF01636.23 ETS78166.1 - 0.0037 17.2 0.1 0.0056 16.6 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ETS78166.1 - 0.052 12.3 0.6 0.07 11.9 0.1 1.4 2 0 0 2 2 2 0 Fungal protein kinase SNN_cytoplasm PF09051.10 ETS78166.1 - 0.14 12.0 0.8 0.37 10.7 0.8 1.7 1 0 0 1 1 1 0 Stannin cytoplasmic Pkinase_Tyr PF07714.17 ETS78166.1 - 0.15 11.3 0.0 6.7 5.9 0.0 3.1 2 1 0 2 2 2 0 Protein tyrosine kinase DJ-1_PfpI PF01965.24 ETS78167.1 - 6.8e-19 68.3 0.0 8.2e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 ETS78167.1 - 0.029 14.1 0.0 0.067 13.0 0.0 1.6 2 0 0 2 2 2 0 Glutamine amidotransferase class-I Acyl_transf_3 PF01757.22 ETS78168.1 - 1.9e-29 102.8 36.9 2.7e-29 102.3 36.9 1.2 1 0 0 1 1 1 1 Acyltransferase family Stealth_CR2 PF11380.8 ETS78169.1 - 1.2e-17 64.0 1.4 5.9e-16 58.6 1.4 2.7 1 1 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR4 PF17103.5 ETS78169.1 - 5.2e-07 29.4 0.0 1.8e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Stealth protein CR4, conserved region 4 Stealth_CR1 PF17101.5 ETS78169.1 - 1.8e-06 27.5 0.0 4.2e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR3 PF17102.5 ETS78169.1 - 0.033 14.1 0.2 0.075 13.0 0.2 1.7 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 TMEM144 PF07857.12 ETS78170.1 - 0.014 14.4 0.8 0.014 14.4 0.8 2.2 2 0 0 2 2 2 0 Transmembrane family, TMEM144 of transporters Wzy_C_2 PF11846.8 ETS78170.1 - 1.4 8.8 12.2 1.9 8.4 0.0 3.3 1 1 3 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal ABC_tran PF00005.27 ETS78171.1 - 1.2e-45 155.4 0.0 5.1e-23 82.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS78171.1 - 5.6e-31 108.2 33.4 1.3e-26 93.8 19.3 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ETS78171.1 - 2.9e-09 36.7 5.9 0.0021 17.5 1.3 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETS78171.1 - 8.5e-07 29.1 3.3 0.18 11.5 0.0 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ETS78171.1 - 1.1e-05 25.7 2.9 0.13 12.5 0.2 3.6 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 ETS78171.1 - 4.2e-05 23.2 0.9 3 7.4 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 ETS78171.1 - 4.5e-05 24.0 3.8 0.03 14.8 0.5 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 ETS78171.1 - 5.7e-05 23.6 1.6 0.0045 17.4 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ETS78171.1 - 9.4e-05 22.4 0.1 0.27 11.1 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 ETS78171.1 - 0.00029 20.0 0.4 0.62 9.1 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_24 PF13479.6 ETS78171.1 - 0.00034 20.4 1.1 0.49 10.1 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_29 PF13555.6 ETS78171.1 - 0.00039 20.1 0.8 0.084 12.6 0.3 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 ETS78171.1 - 0.00065 20.2 1.1 1.1 9.8 0.1 2.7 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 ETS78171.1 - 0.00076 19.5 0.6 0.26 11.4 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ETS78171.1 - 0.0017 18.8 2.8 2.6 8.4 0.0 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 ETS78171.1 - 0.0017 18.5 0.1 0.6 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ETS78171.1 - 0.0061 16.3 0.8 6.9 6.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 ETS78171.1 - 0.0067 16.2 0.9 3 7.5 0.3 2.2 2 0 0 2 2 2 2 AAA ATPase domain cobW PF02492.19 ETS78171.1 - 0.0095 15.5 1.8 3.2 7.3 0.2 2.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 ETS78171.1 - 0.017 14.5 0.4 0.66 9.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 ETS78171.1 - 0.019 14.1 0.3 8.5 5.5 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain DUF87 PF01935.17 ETS78171.1 - 0.024 14.7 2.3 0.09 12.9 0.3 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 ETS78171.1 - 0.034 13.8 0.0 7.1 6.2 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 ETS78171.1 - 0.035 13.6 0.2 4.6 6.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 ETS78171.1 - 0.061 12.2 1.1 4.7 6.0 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 ETS78171.1 - 0.085 12.8 3.4 5.6 6.9 0.1 2.9 3 0 0 3 3 2 0 NACHT domain RNA_helicase PF00910.22 ETS78171.1 - 0.089 13.2 0.1 29 5.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 ETS78171.1 - 0.1 12.6 0.1 17 5.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 ETS78171.1 - 0.13 12.0 3.6 16 5.2 0.1 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein Dynamin_N PF00350.23 ETS78171.1 - 0.13 12.3 0.4 23 5.0 0.1 2.6 2 0 0 2 2 2 0 Dynamin family TsaE PF02367.17 ETS78171.1 - 0.14 12.1 0.2 2.7 8.0 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GTP_EFTU PF00009.27 ETS78171.1 - 0.16 11.5 0.2 18 4.8 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NTPase_1 PF03266.15 ETS78171.1 - 0.23 11.4 2.4 5.2 7.0 0.1 2.6 2 0 0 2 2 2 0 NTPase SbcCD_C PF13558.6 ETS78171.1 - 0.26 11.6 1.3 12 6.3 0.1 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 ETS78171.1 - 0.65 10.2 2.7 1.2 9.4 0.2 2.2 2 0 0 2 2 2 0 AAA domain Tht1 PF04163.12 ETS78172.1 - 1.1e-06 27.7 0.5 1.9e-06 27.0 0.5 1.3 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein Lipoprotein_7 PF01540.16 ETS78172.1 - 0.056 12.7 1.8 0.96 8.7 0.0 2.2 1 1 1 2 2 2 0 Adhesin lipoprotein NPV_P10 PF05531.12 ETS78172.1 - 0.22 12.0 3.6 3.5 8.1 0.0 3.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein HAUS6_N PF14661.6 ETS78172.1 - 5 6.6 6.0 12 5.4 1.1 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Ribosomal_L6 PF00347.23 ETS78173.1 - 5e-20 72.0 0.0 4.1e-10 40.2 0.0 2.6 2 1 0 2 2 2 2 Ribosomal protein L6 Inositol_P PF00459.25 ETS78174.1 - 2.9e-53 181.1 2.9 1.4e-52 178.9 2.9 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family Rsm1 PF08600.10 ETS78175.1 - 5.9e-27 93.7 0.7 6.2e-26 90.4 0.0 2.4 2 0 0 2 2 2 1 Rsm1-like zf-C3HC PF07967.13 ETS78175.1 - 9.2e-27 93.7 0.1 7.5e-21 74.6 0.3 2.7 2 1 0 2 2 2 2 C3HC zinc finger-like BIR PF00653.21 ETS78175.1 - 0.017 15.7 0.6 0.26 12.0 0.5 2.3 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain E1-E2_ATPase PF00122.20 ETS78176.1 - 5.9e-49 166.0 5.5 4e-48 163.3 0.6 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 ETS78176.1 - 1.7e-33 116.7 0.4 3.6e-33 115.6 0.4 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 ETS78176.1 - 8.8e-14 51.7 0.0 2.1e-11 44.1 0.0 2.7 2 0 0 2 2 2 1 Heavy-metal-associated domain HAD PF12710.7 ETS78176.1 - 3.9e-05 24.1 0.2 0.00011 22.6 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ETS78176.1 - 5.7e-05 23.0 0.3 0.00035 20.4 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Importin_rep_3 PF18806.1 ETS78176.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Importin 13 repeat BCLP PF12304.8 ETS78176.1 - 0.084 12.4 0.1 0.24 11.0 0.1 1.7 1 0 0 1 1 1 0 Beta-casein like protein HRG PF16954.5 ETS78176.1 - 3.7 8.0 11.0 0.67 10.4 0.2 3.4 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Ribonuclease_T2 PF00445.18 ETS78178.1 - 1.2e-42 146.2 1.3 2.2e-42 145.3 1.3 1.4 1 0 0 1 1 1 1 Ribonuclease T2 family HEAT_EZ PF13513.6 ETS78179.1 - 1e-19 70.6 11.3 3.3e-06 27.5 1.2 9.6 10 1 1 11 11 9 3 HEAT-like repeat HEAT_2 PF13646.6 ETS78179.1 - 5.9e-16 58.6 15.1 0.00071 19.9 0.1 8.6 6 3 1 8 8 7 3 HEAT repeats HEAT PF02985.22 ETS78179.1 - 9.5e-12 44.1 10.5 0.029 14.6 0.2 9.1 11 0 0 11 11 8 3 HEAT repeat Adaptin_N PF01602.20 ETS78179.1 - 7.7e-11 41.2 1.8 9.6e-05 21.1 0.0 4.5 3 2 1 4 4 4 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 ETS78179.1 - 1.7e-10 41.3 0.9 0.13 12.9 0.0 7.0 5 2 3 8 8 8 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ETS78179.1 - 1.9e-09 37.8 6.1 0.0079 16.3 0.2 4.8 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 ETS78179.1 - 4e-08 33.0 0.1 4.9e-07 29.6 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain RIX1 PF08167.12 ETS78179.1 - 3.3e-07 30.2 0.0 0.09 12.5 0.0 4.5 3 2 1 4 4 4 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 ETS78179.1 - 1.4e-06 28.1 1.6 0.022 14.3 0.0 3.9 4 0 0 4 4 4 2 CLASP N terminal IFRD PF05004.13 ETS78179.1 - 0.00016 20.9 1.0 0.00016 20.9 1.0 4.4 3 2 0 4 4 4 2 Interferon-related developmental regulator (IFRD) Arm PF00514.23 ETS78179.1 - 0.00043 20.2 8.9 9.3 6.5 0.0 7.1 9 0 0 9 9 7 0 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 ETS78179.1 - 0.0035 16.9 0.0 6.9 6.1 0.0 3.6 3 0 0 3 3 3 1 Tti2 family Nop14 PF04147.12 ETS78179.1 - 0.022 13.0 1.0 0.051 11.8 0.5 1.8 2 0 0 2 2 2 0 Nop14-like family V-ATPase_H_C PF11698.8 ETS78179.1 - 0.034 14.3 2.0 31 4.7 0.1 4.7 4 1 1 5 5 4 0 V-ATPase subunit H YukD PF08817.10 ETS78179.1 - 0.034 14.8 0.8 11 6.8 0.1 4.0 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD FlaF PF07309.11 ETS78179.1 - 0.042 13.8 0.3 0.57 10.2 0.0 3.0 3 0 0 3 3 3 0 Flagellar protein FlaF RTP1_C1 PF10363.9 ETS78179.1 - 0.055 13.7 1.2 3.4 7.9 0.0 4.0 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 ETS78179.1 - 0.074 13.0 6.3 4.8 7.1 0.4 4.4 4 1 0 4 4 4 0 Myosin-binding striated muscle assembly central MMS19_C PF12460.8 ETS78179.1 - 0.083 12.0 7.8 0.089 11.9 0.0 3.6 3 2 0 3 3 3 0 RNAPII transcription regulator C-terminal HEAT_PBS PF03130.16 ETS78179.1 - 0.34 11.7 5.6 28 5.8 0.1 5.9 6 0 0 6 6 5 0 PBS lyase HEAT-like repeat GCIP PF13324.6 ETS78179.1 - 0.4 10.3 5.5 2.9 7.4 4.5 2.7 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting zf-U1 PF06220.12 ETS78180.1 - 4.8e-07 29.4 0.4 7.7e-07 28.8 0.4 1.3 1 0 0 1 1 1 1 U1 zinc finger Herpes_pp85 PF04637.12 ETS78180.1 - 0.0061 15.0 1.6 0.0092 14.4 1.6 1.1 1 0 0 1 1 1 1 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF4224 PF13986.6 ETS78180.1 - 0.077 12.9 0.1 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) PIR PF00399.19 ETS78181.1 - 1.9e-08 33.7 24.1 5.3e-06 25.8 4.6 4.4 3 0 0 3 3 3 3 Yeast PIR protein repeat Pec_lyase_C PF00544.19 ETS78183.1 - 1.3e-42 145.8 10.5 1.8e-42 145.3 10.5 1.2 1 0 0 1 1 1 1 Pectate lyase Phage_attach PF05354.11 ETS78183.1 - 0.00035 20.4 4.7 0.11 12.4 0.6 2.5 2 1 0 2 2 2 2 Phage Head-Tail Attachment Glyco_hydro_65m PF03632.15 ETS78183.1 - 0.017 14.0 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain fn3_3 PF14686.6 ETS78184.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II A_deaminase PF00962.22 ETS78185.1 - 1.2e-24 87.3 0.0 8.3e-24 84.5 0.0 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase ARL6IP6 PF15062.6 ETS78185.1 - 0.026 14.7 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix Pkinase PF00069.25 ETS78187.1 - 1.9e-70 237.3 0.0 2.4e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS78187.1 - 1.9e-32 112.6 0.0 3.4e-32 111.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ETS78187.1 - 0.00028 20.0 0.0 0.0016 17.5 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ETS78187.1 - 0.0049 16.2 0.0 0.01 15.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ETS78187.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ETS78187.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 ETS78187.1 - 0.23 10.8 0.1 0.61 9.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2OG-FeII_Oxy_2 PF13532.6 ETS78188.1 - 4.6e-31 108.5 0.0 8.6e-31 107.6 0.0 1.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Lipase_GDSL_2 PF13472.6 ETS78189.1 - 5.8e-05 23.6 5.9 8.7e-05 23.0 5.9 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS78189.1 - 9.3e-05 22.5 0.0 0.00012 22.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ceramidase_alk PF04734.13 ETS78190.1 - 4.9e-220 731.5 0.1 5.9e-220 731.2 0.1 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 ETS78190.1 - 2.2e-64 216.4 0.2 3.7e-64 215.6 0.2 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal DUF1604 PF07713.13 ETS78191.1 - 4.1e-40 135.5 2.2 1.1e-39 134.1 2.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.23 ETS78191.1 - 4.8e-07 29.6 3.2 2.4e-06 27.3 1.4 2.6 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 ETS78191.1 - 0.0026 17.8 0.2 0.0026 17.8 0.2 3.2 4 0 0 4 4 4 1 G-patch domain Pkinase PF00069.25 ETS78192.1 - 8.5e-69 231.9 0.0 1.5e-68 231.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS78192.1 - 3.6e-39 134.6 0.0 1.9e-38 132.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 ETS78192.1 - 5.8e-20 70.8 0.1 1.1e-19 70.0 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 ETS78192.1 - 1.8e-06 27.1 0.0 3.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ETS78192.1 - 0.00012 21.5 0.0 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ETS78192.1 - 0.00013 21.4 0.1 0.00024 20.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ETS78192.1 - 0.0034 17.4 0.0 0.024 14.6 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 ETS78192.1 - 0.054 13.1 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 RIO1 family SbcCD_C PF13558.6 ETS78192.1 - 0.075 13.3 0.9 2.1 8.6 0.3 2.7 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF2014 PF09427.10 ETS78193.1 - 6.2e-114 379.8 2.8 9.2e-114 379.2 2.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 ETS78193.1 - 8.4e-17 60.9 0.8 1.7e-16 59.9 0.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SUIM_assoc PF16619.5 ETS78193.1 - 1.2 9.3 11.2 7.1 6.8 0.6 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CIA30 PF08547.12 ETS78194.1 - 4.2e-41 140.6 0.0 5.1e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) bZIP_1 PF00170.21 ETS78195.1 - 0.00031 20.8 6.4 0.00049 20.1 6.4 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ETS78195.1 - 0.017 15.2 9.0 0.026 14.6 9.0 1.2 1 0 0 1 1 1 0 Basic region leucine zipper Na_H_Exchanger PF00999.21 ETS78196.1 - 7.7e-60 202.7 49.6 1.2e-59 202.1 49.6 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Utp14 PF04615.13 ETS78198.1 - 1.8e-186 622.0 70.7 1.8e-186 622.0 70.7 2.8 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.9 ETS78199.1 - 4.1e-19 68.5 0.2 7.2e-19 67.7 0.2 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF1771 PF08590.10 ETS78200.1 - 8.6e-06 26.0 3.7 2e-05 24.9 3.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 ETS78200.1 - 0.058 13.8 0.3 0.2 12.0 0.3 1.9 1 0 0 1 1 1 0 Smr domain Phage_Mu_Gp45 PF06890.12 ETS78200.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein PAP1 PF08601.10 ETS78201.1 - 1.3e-79 268.7 29.0 5.5e-59 200.8 2.4 3.8 1 1 3 4 4 4 2 Transcription factor PAP1 bZIP_1 PF00170.21 ETS78201.1 - 2e-09 37.4 12.4 3.9e-09 36.5 12.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor ERM PF00769.19 ETS78201.1 - 7.4e-05 22.7 4.1 0.00011 22.1 4.1 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family bZIP_2 PF07716.15 ETS78201.1 - 0.00029 20.8 14.1 0.0012 18.9 14.1 2.0 1 1 0 1 1 1 1 Basic region leucine zipper Fmp27_WPPW PF10359.9 ETS78201.1 - 0.0022 16.9 2.7 0.0032 16.4 2.7 1.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Cluap1 PF10234.9 ETS78201.1 - 0.0084 15.5 8.1 0.013 14.9 8.1 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 CCDC158 PF15921.5 ETS78201.1 - 0.0099 13.8 1.3 0.014 13.3 1.3 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 158 SHE3 PF17078.5 ETS78201.1 - 0.014 15.1 8.2 0.024 14.3 8.2 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Nop53 PF07767.11 ETS78201.1 - 0.04 13.3 16.1 0.062 12.7 16.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Cnn_1N PF07989.11 ETS78201.1 - 0.041 14.0 5.7 0.098 12.8 5.7 1.6 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF812 PF05667.11 ETS78201.1 - 0.041 12.8 8.2 0.062 12.2 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) bZIP_Maf PF03131.17 ETS78201.1 - 0.043 14.3 10.3 0.086 13.4 10.3 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor APG6_N PF17675.1 ETS78201.1 - 0.11 13.1 8.9 0.24 11.9 8.9 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region dsrm PF00035.26 ETS78201.1 - 0.11 13.3 0.1 0.28 11.9 0.1 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif HAUS-augmin3 PF14932.6 ETS78201.1 - 0.13 11.9 5.4 0.22 11.1 5.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 ETS78201.1 - 0.13 12.9 2.1 0.3 11.7 2.1 1.6 1 0 0 1 1 1 0 SlyX FlaC_arch PF05377.11 ETS78201.1 - 0.17 12.3 1.9 0.32 11.4 1.9 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) SPT16 PF08644.11 ETS78201.1 - 0.18 12.0 3.5 0.36 11.0 3.5 1.4 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) TMCO5 PF14992.6 ETS78201.1 - 0.47 10.0 5.8 0.89 9.1 5.8 1.3 1 0 0 1 1 1 0 TMCO5 family Noelin-1 PF12308.8 ETS78201.1 - 0.55 10.2 5.3 0.58 10.2 3.1 1.9 2 0 0 2 2 2 0 Neurogenesis glycoprotein TMF_DNA_bd PF12329.8 ETS78201.1 - 0.59 10.2 10.1 1.2 9.2 10.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 ETS78201.1 - 1.1 9.3 8.6 2.2 8.4 8.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 ETS78201.1 - 1.5 8.6 3.8 2.9 7.7 3.8 1.4 1 0 0 1 1 1 0 Septum formation initiator Pox_G5 PF04599.12 ETS78201.1 - 2.7 6.9 4.4 4 6.3 4.4 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein TMPIT PF07851.13 ETS78201.1 - 6.2 6.0 5.1 2.6 7.2 2.8 1.4 2 0 0 2 2 2 0 TMPIT-like protein BSD PF03909.17 ETS78202.1 - 7.8e-21 73.8 0.1 1.6e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 BSD domain ArAE_2_N PF10337.9 ETS78202.1 - 0.055 12.5 0.4 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal WGG PF10273.9 ETS78203.1 - 2.4e-29 101.8 0.6 3.9e-29 101.1 0.6 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 ETS78203.1 - 0.042 14.0 0.0 0.042 14.0 0.0 2.1 2 1 1 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF1280 PF06918.14 ETS78203.1 - 0.094 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) TFIIF_alpha PF05793.12 ETS78203.1 - 0.15 10.6 11.8 0.17 10.5 11.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-B_dimeris PF09026.10 ETS78203.1 - 3.7 8.0 12.3 9.5 6.7 12.3 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 ETS78203.1 - 3.7 6.8 10.3 4.8 6.4 10.3 1.1 1 0 0 1 1 1 0 NOA36 protein Trypan_PARP PF05887.11 ETS78203.1 - 6.4 6.8 8.0 5.7 6.9 5.8 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Abhydrolase_3 PF07859.13 ETS78204.1 - 1e-40 139.9 0.0 4.7e-31 108.3 0.1 2.7 1 1 1 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS78204.1 - 2.1e-14 53.2 0.0 1.2e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 ETS78204.1 - 0.035 13.0 3.6 0.065 12.1 0.3 2.6 2 1 0 2 2 2 0 Carboxylesterase family Hydrolase_4 PF12146.8 ETS78204.1 - 0.044 13.0 0.0 0.1 11.8 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Putative_PNPOx PF01243.20 ETS78205.1 - 3.5e-08 33.5 0.0 2.8e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.21 ETS78205.1 - 0.0031 18.1 0.0 0.006 17.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain CTP_transf_like PF01467.26 ETS78206.1 - 2.6e-19 69.8 0.0 3.4e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like NPC1_N PF16414.5 ETS78208.1 - 1.6e-81 273.4 10.4 2.4e-81 272.9 10.4 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 ETS78208.1 - 3.1e-78 263.7 12.2 6.4e-50 170.1 0.1 2.9 3 0 0 3 3 3 2 Patched family Sterol-sensing PF12349.8 ETS78208.1 - 4.9e-52 175.8 6.5 4.9e-52 175.8 6.5 2.8 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 ETS78208.1 - 9e-06 24.8 7.6 9e-06 24.8 7.6 2.8 2 1 0 2 2 2 1 MMPL family Folate_rec PF03024.14 ETS78208.1 - 1.6e-05 24.8 2.3 3.2e-05 23.9 2.3 1.4 1 0 0 1 1 1 1 Folate receptor family ACR_tran PF00873.19 ETS78208.1 - 0.1 10.2 18.7 0.037 11.7 11.6 2.3 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family Trp_oprn_chp PF09534.10 ETS78209.1 - 0.49 10.2 16.3 0.066 13.0 11.5 1.9 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) HET PF06985.11 ETS78210.1 - 8.5e-12 45.6 0.1 1.6e-11 44.7 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_7 PF00840.20 ETS78211.1 - 2.7e-204 678.9 21.9 3e-204 678.7 21.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 T7SS_ESX_EspC PF10824.8 ETS78212.1 - 0.025 15.1 1.2 0.067 13.7 1.2 1.7 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm FIST_C PF10442.9 ETS78212.1 - 0.061 13.3 0.1 3.4 7.6 0.0 2.6 1 1 0 2 2 2 0 FIST C domain KCH PF16944.5 ETS78214.1 - 6.5e-96 320.9 6.8 7.8e-96 320.7 6.8 1.1 1 0 0 1 1 1 1 Fungal potassium channel PAS_9 PF13426.7 ETS78215.1 - 1.2e-15 57.6 0.0 1.7e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 ETS78215.1 - 0.063 13.3 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 PAS fold PAS_4 PF08448.10 ETS78215.1 - 0.11 12.7 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_3 PF08447.12 ETS78215.1 - 0.13 12.5 0.0 1 9.7 0.0 2.0 2 0 0 2 2 2 0 PAS fold zf-RING_4 PF14570.6 ETS78217.1 - 2e-20 72.3 13.4 3.9e-20 71.4 13.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 ETS78217.1 - 3e-09 36.5 0.0 2.8e-08 33.5 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 ETS78217.1 - 4.7e-07 29.6 7.7 9.9e-07 28.5 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 ETS78217.1 - 8.3e-06 25.3 2.1 2.7e-05 23.7 2.1 1.8 1 0 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 ETS78217.1 - 0.0009 19.1 9.6 0.011 15.6 5.0 2.3 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ETS78217.1 - 0.00091 19.5 10.3 0.0019 18.5 10.3 1.6 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 ETS78217.1 - 0.004 17.1 5.1 0.0071 16.3 5.1 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) SET_assoc PF11767.8 ETS78217.1 - 0.0076 15.9 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.6 ETS78217.1 - 0.021 14.8 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-UDP PF14569.6 ETS78217.1 - 0.03 14.4 4.7 0.074 13.2 4.7 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4 PF00097.25 ETS78217.1 - 0.24 11.3 11.7 0.47 10.4 11.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ETS78217.1 - 0.29 11.1 10.7 0.54 10.3 10.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ETS78217.1 - 2.3 8.2 9.9 4.8 7.1 9.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Complex1_30kDa PF00329.19 ETS78218.1 - 1.6e-44 151.4 0.0 2.3e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit E1_dh PF00676.20 ETS78219.1 - 7.3e-90 300.9 0.0 8.8e-90 300.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 ETS78219.1 - 0.00027 20.7 0.3 0.0035 17.1 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 ETS78219.1 - 0.12 11.6 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Arylsulfotran_2 PF14269.6 ETS78220.1 - 2e-46 158.8 1.2 2e-46 158.8 1.2 1.7 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 ETS78220.1 - 1.1e-17 64.0 0.3 1.8e-17 63.3 0.3 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.21 ETS78220.1 - 0.071 13.1 0.2 23 5.1 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat WD40 PF00400.32 ETS78220.1 - 0.11 13.4 0.6 3.6 8.6 0.1 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat PAS PF00989.25 ETS78220.1 - 0.15 12.1 0.0 8.9 6.3 0.0 2.6 2 0 0 2 2 2 0 PAS fold MFS_1 PF07690.16 ETS78221.1 - 1.5e-17 63.6 23.7 1.5e-17 63.6 23.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Cdh1_DBD_1 PF18196.1 ETS78221.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 Sulfotransfer_4 PF17784.1 ETS78222.1 - 3.2e-72 242.8 0.1 3.9e-72 242.6 0.1 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ETS78222.1 - 2.5e-05 24.8 0.1 0.023 15.1 0.1 2.2 1 1 0 2 2 2 2 Sulfotransferase family Abhydrolase_6 PF12697.7 ETS78223.1 - 1.1e-08 35.9 14.2 3.5e-08 34.3 14.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 ETS78223.1 - 0.0008 18.2 0.0 0.0013 17.5 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 ETS78223.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 HECT PF00632.25 ETS78224.1 - 3.7e-73 246.7 0.0 5.8e-73 246.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 ETS78224.1 - 0.00018 21.4 1.3 1.5 9.0 0.1 5.6 6 1 1 7 7 7 1 Armadillo/beta-catenin-like repeat Spem1 PF15670.5 ETS78224.1 - 0.00072 19.2 1.1 0.087 12.4 1.5 2.8 2 0 0 2 2 2 1 Spermatid maturation protein 1 SDA1 PF05285.12 ETS78224.1 - 0.0012 18.3 13.6 0.0012 18.3 13.6 3.1 3 0 0 3 3 3 1 SDA1 HEAT PF02985.22 ETS78224.1 - 0.0025 17.9 0.4 0.59 10.5 0.0 4.1 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 ETS78224.1 - 0.034 14.7 0.1 0.72 10.4 0.0 3.2 3 0 0 3 3 3 0 HEAT-like repeat Clr5 PF14420.6 ETS78224.1 - 0.049 13.9 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 Clr5 domain Fungal_trans PF04082.18 ETS78225.1 - 3.6e-15 55.7 1.7 6.5e-15 54.9 1.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pectate_lyase_3 PF12708.7 ETS78226.1 - 8.2e-103 342.8 14.9 2.1e-87 292.5 5.8 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 ETS78226.1 - 2.7e-05 23.8 4.9 0.0074 16.0 0.3 2.5 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Glyco_hydro_28 PF00295.17 ETS78226.1 - 0.0045 16.1 0.7 0.0095 15.0 0.7 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 PhyH PF05721.13 ETS78227.1 - 6.7e-09 36.3 0.3 4.5e-08 33.6 0.3 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MARVEL PF01284.23 ETS78228.1 - 0.028 14.4 1.9 0.059 13.4 1.9 1.6 1 1 0 1 1 1 0 Membrane-associating domain Bee_toxin PF17454.2 ETS78228.1 - 0.071 13.2 1.2 0.16 12.0 1.2 1.5 1 0 0 1 1 1 0 Honey bee toxin TFB6 PF17110.5 ETS78228.1 - 0.076 12.8 0.3 0.15 11.8 0.3 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH FAM117 PF15388.6 ETS78228.1 - 0.15 11.4 12.8 0.22 10.9 12.8 1.2 1 0 0 1 1 1 0 Protein Family FAM117 ORC6 PF05460.13 ETS78228.1 - 0.26 10.5 4.8 0.33 10.2 4.8 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ctr PF04145.15 ETS78228.1 - 0.43 11.2 3.1 0.3 11.7 0.4 2.1 2 0 0 2 2 2 0 Ctr copper transporter family Spt20 PF12090.8 ETS78228.1 - 0.87 9.2 11.6 1.7 8.2 11.6 1.4 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 ETS78228.1 - 5.3 8.1 7.2 11 7.1 5.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Uds1 PF15456.6 ETS78228.1 - 8.4 6.6 10.5 0.55 10.4 5.4 1.6 2 0 0 2 2 2 0 Up-regulated During Septation F-box PF00646.33 ETS78229.1 - 0.032 14.1 0.5 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 F-box domain Methyltransf_16 PF10294.9 ETS78230.1 - 2.6e-10 40.3 0.0 4.1e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 ETS78230.1 - 0.0062 16.0 0.0 0.0089 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 ETS78230.1 - 0.061 12.6 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Surp PF01805.20 ETS78232.1 - 4.7e-12 45.7 0.1 1.4e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 Surp module HBS1_N PF08938.10 ETS78232.1 - 0.064 13.6 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 HBS1 N-terminus DAO PF01266.24 ETS78233.1 - 6.5e-39 134.5 1.9 7.7e-39 134.3 1.9 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS78233.1 - 9.9e-06 25.6 0.6 0.09 12.8 0.0 2.5 2 1 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ETS78233.1 - 6.2e-05 23.2 0.1 0.00017 21.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS78233.1 - 7.1e-05 22.2 0.0 0.11 11.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS78233.1 - 0.001 18.2 2.6 0.02 14.0 2.7 2.1 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 ETS78233.1 - 0.008 15.3 0.0 0.024 13.7 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ETS78233.1 - 0.014 14.7 0.0 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 ETS78233.1 - 0.016 14.3 0.1 0.073 12.1 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 ETS78233.1 - 0.12 11.6 0.0 0.69 9.1 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Sacchrp_dh_NADP PF03435.18 ETS78233.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TBP PF00352.21 ETS78234.1 - 1.4e-67 223.7 0.1 6.9e-33 112.5 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 ETS78234.1 - 4.3e-05 23.6 0.0 0.22 11.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 ETS78234.1 - 0.13 12.1 0.1 0.67 9.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) ETF_QO PF05187.13 ETS78236.1 - 1.9e-48 162.9 0.6 3.1e-48 162.2 0.6 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 ETS78236.1 - 4.9e-08 33.1 0.0 1.6e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS78236.1 - 2e-07 30.9 0.3 0.00019 21.1 0.5 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 ETS78236.1 - 3.1e-05 23.4 0.0 0.0021 17.4 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 ETS78236.1 - 5.7e-05 22.5 0.0 0.00017 20.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS78236.1 - 0.00023 20.4 0.3 0.0043 16.2 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 ETS78236.1 - 0.00025 19.9 0.4 0.00036 19.4 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 ETS78236.1 - 0.00043 19.3 0.0 0.15 10.8 0.1 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 ETS78236.1 - 0.00076 18.8 0.1 0.0013 18.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ETS78236.1 - 0.0011 18.4 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS78236.1 - 0.0028 17.7 0.1 0.0077 16.2 0.2 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 ETS78236.1 - 0.005 17.4 0.0 6.4 7.4 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS78236.1 - 0.0078 15.5 0.3 0.011 15.0 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 ETS78236.1 - 0.009 16.6 1.0 0.027 15.1 1.0 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 ETS78236.1 - 0.055 12.5 0.3 0.081 12.0 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 ETS78236.1 - 0.13 11.3 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_2 PF12797.7 ETS78236.1 - 0.15 12.2 0.7 0.44 10.7 0.7 1.8 1 0 0 1 1 1 0 4Fe-4S binding domain AlaDh_PNT_C PF01262.21 ETS78236.1 - 0.21 10.8 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Zn_clus PF00172.18 ETS78237.1 - 1.8e-07 31.1 7.6 1.8e-07 31.1 7.6 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 ETS78237.1 - 0.00026 21.3 0.8 0.00078 19.8 0.8 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS78237.1 - 0.053 14.4 1.6 0.053 14.4 1.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 ETS78237.1 - 0.12 12.8 0.1 0.12 12.8 0.1 1.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ham1p_like PF01725.16 ETS78238.1 - 7.2e-51 172.8 0.0 8e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family BEN PF10523.9 ETS78239.1 - 0.072 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 BEN domain RdDM_RDM1 PF09187.10 ETS78239.1 - 0.11 12.6 0.4 26 4.9 0.0 2.7 3 0 0 3 3 3 0 RNA-directed DNA methylation 1 Ceramidase PF05875.12 ETS78239.1 - 0.18 11.2 0.1 0.18 11.2 0.1 2.3 2 0 0 2 2 2 0 Ceramidase An_peroxidase PF03098.15 ETS78240.1 - 5.9e-118 394.7 0.0 7.5e-118 394.4 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase LURAP PF14854.6 ETS78241.1 - 0.075 13.0 0.5 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 Leucine rich adaptor protein Glyco_hydro_75 PF07335.11 ETS78242.1 - 1.9e-52 177.8 0.1 2e-37 129.0 0.0 2.2 2 0 0 2 2 2 2 Fungal chitosanase of glycosyl hydrolase group 75 Peptidase_S28 PF05577.12 ETS78243.1 - 2e-46 158.7 0.2 2.9e-46 158.2 0.2 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 zf-primase PF09329.11 ETS78244.1 - 2.4e-18 65.7 1.4 4.2e-18 64.9 1.4 1.4 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.25 ETS78244.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain IRK PF01007.20 ETS78244.1 - 0.24 11.2 0.1 0.4 10.5 0.1 1.2 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain DUF3619 PF12279.8 ETS78244.1 - 1.3 9.4 6.0 1 9.7 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) RNase_H2-Ydr279 PF09468.10 ETS78245.1 - 2.9e-37 128.3 4.2 8.9e-37 126.7 0.3 2.6 1 1 1 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 ETS78245.1 - 2.1e-25 88.8 0.0 4.4e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain Herpes_UL3 PF03369.13 ETS78245.1 - 0.071 13.7 0.3 0.2 12.2 0.3 1.7 1 0 0 1 1 1 0 Herpesvirus UL3 protein DUF3340 PF11818.8 ETS78245.1 - 0.083 13.1 7.7 0.32 11.2 7.7 2.0 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DUF3727 PF12527.8 ETS78245.1 - 0.12 12.7 0.1 0.12 12.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3727) DASH_Duo1 PF08651.10 ETS78246.1 - 5.8e-31 106.1 0.7 8.2e-31 105.6 0.7 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF3340 PF11818.8 ETS78246.1 - 0.0013 19.0 3.9 0.0019 18.4 3.9 1.2 1 0 0 1 1 1 1 C-terminal domain of tail specific protease (DUF3340) DUF1682 PF07946.14 ETS78246.1 - 0.092 11.9 6.3 0.13 11.5 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4407 PF14362.6 ETS78246.1 - 0.16 11.3 5.3 0.2 11.0 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 ETS78248.1 - 4.1e-15 55.9 0.0 1.8e-14 53.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS78248.1 - 7.1e-09 35.3 0.0 9.4e-08 31.7 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase DCB PF16213.5 ETS78248.1 - 0.0001 22.0 0.5 0.0014 18.4 0.1 2.3 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Aminotran_4 PF01063.19 ETS78249.1 - 3.1e-35 122.1 0.0 3.9e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV ESSS PF10183.9 ETS78250.1 - 7.9e-19 67.8 0.0 9.1e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Beta-lactamase PF00144.24 ETS78251.1 - 1.1e-42 146.5 5.5 1.6e-42 145.9 5.5 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 ETS78251.1 - 2.8e-10 40.6 0.0 5.3e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) SIR2 PF02146.17 ETS78252.1 - 5.1e-57 192.6 0.0 8.6e-57 191.9 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 ETS78252.1 - 3.1e-05 23.8 0.0 8.9e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 ETS78252.1 - 0.00058 19.6 1.1 0.64 9.8 0.0 2.9 4 0 0 4 4 4 2 Thiamine pyrophosphate enzyme, central domain WD-3 PF09765.9 ETS78252.1 - 0.039 13.3 0.2 0.064 12.6 0.2 1.2 1 0 0 1 1 1 0 WD-repeat region Phage_TAC_12 PF12363.8 ETS78252.1 - 0.064 13.7 0.3 0.19 12.2 0.3 1.9 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC Cation_ATPase_C PF00689.21 ETS78253.1 - 3.6e-43 147.4 7.2 3.6e-43 147.4 7.2 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ETS78253.1 - 2.8e-33 115.0 0.7 2.8e-33 115.0 0.7 3.7 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 ETS78253.1 - 2.3e-22 78.9 0.0 4.5e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ETS78253.1 - 3.1e-20 73.4 0.0 7.2e-20 72.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ETS78253.1 - 1.2e-06 28.1 0.0 7e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ETS78253.1 - 2.3e-05 24.3 0.5 7.5e-05 22.6 0.4 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 ETS78253.1 - 0.026 13.4 4.9 0.018 13.9 2.5 1.9 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG DUF2373 PF10180.9 ETS78253.1 - 0.2 11.5 0.1 0.93 9.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) Bep_C_terminal PF17841.1 ETS78254.1 - 0.1 12.9 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) MMACHC PF16690.5 ETS78254.1 - 0.18 11.4 0.2 0.56 9.8 0.0 1.7 2 0 0 2 2 2 0 Methylmalonic aciduria and homocystinuria type C family TTL PF03133.15 ETS78255.1 - 6.4e-57 192.9 0.0 1.1e-56 192.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 ETS78255.1 - 2e-49 168.0 0.0 3.3e-49 167.3 0.0 1.4 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 ETS78255.1 - 0.0024 17.2 0.0 0.0071 15.6 0.0 1.7 2 0 0 2 2 2 1 YheC/D like ATP-grasp Glyco_trans_4_4 PF13579.6 ETS78255.1 - 0.0058 17.1 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 ETS78255.1 - 0.028 14.4 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 FCH PF00611.23 ETS78256.1 - 2.1e-15 56.7 0.0 7.1e-15 55.1 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 ETS78256.1 - 2.3e-12 46.3 0.0 4.3e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ETS78256.1 - 8.3e-11 41.6 0.0 1.7e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ETS78256.1 - 5.7e-10 38.7 0.0 1.7e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Seipin PF06775.14 ETS78257.1 - 3.1e-52 177.6 1.4 4.4e-52 177.1 1.4 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) HET PF06985.11 ETS78259.1 - 4.1e-12 46.7 2.1 5.4e-10 39.8 2.1 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Takusan PF04822.13 ETS78259.1 - 0.19 11.6 0.1 0.34 10.8 0.1 1.3 1 0 0 1 1 1 0 Takusan Bac_luciferase PF00296.20 ETS78260.1 - 5.2e-60 203.5 0.4 6.8e-60 203.1 0.4 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase AAA_16 PF13191.6 ETS78261.1 - 2.1e-06 28.2 0.1 6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.14 ETS78261.1 - 0.0023 17.5 0.0 0.029 13.9 0.0 2.2 2 0 0 2 2 2 1 Putative serine esterase (DUF676) NACHT PF05729.12 ETS78261.1 - 0.019 14.9 1.0 0.078 12.9 1.0 2.0 1 1 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 ETS78261.1 - 0.026 13.7 0.0 0.066 12.4 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain PGAP1 PF07819.13 ETS78261.1 - 0.029 14.1 0.0 0.072 12.8 0.0 1.7 1 0 0 1 1 1 0 PGAP1-like protein AAA_22 PF13401.6 ETS78261.1 - 0.049 13.9 0.0 0.24 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 ETS78261.1 - 0.086 12.7 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Peptidase_Mx1 PF15890.5 ETS78262.1 - 0.11 11.9 0.3 0.16 11.3 0.3 1.2 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase Aim21 PF11489.8 ETS78263.1 - 1.8e-189 632.2 67.9 1.8e-189 632.2 67.9 2.2 2 0 0 2 2 2 1 Altered inheritance of mitochondria protein 21 Cg6151-P PF10233.9 ETS78264.1 - 2.5e-40 137.3 15.1 2.9e-40 137.1 15.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Chordopox_G3 PF06129.12 ETS78264.1 - 3.2 8.5 5.4 3 8.6 0.1 2.4 2 1 0 2 2 2 0 Chordopoxvirus G3 protein CitMHS PF03600.16 ETS78264.1 - 6.5 5.9 11.5 6.9 5.8 11.5 1.1 1 0 0 1 1 1 0 Citrate transporter NTF2 PF02136.20 ETS78265.1 - 7.5e-32 110.4 0.8 8.4e-32 110.3 0.8 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 ETS78265.1 - 0.0041 17.5 0.0 0.0048 17.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) FUSC_2 PF13515.6 ETS78266.1 - 2.7e-17 63.1 34.8 4.1e-15 56.0 12.3 2.7 2 0 0 2 2 2 2 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 ETS78266.1 - 2.6e-07 30.1 4.2 1.2e-06 27.9 1.3 4.9 3 1 1 5 5 5 2 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 ETS78266.1 - 1.8e-06 27.0 3.8 1.8e-06 27.0 3.8 2.8 3 0 0 3 3 3 1 Aluminium activated malate transporter ArAE_2 PF10334.9 ETS78266.1 - 7.3e-06 26.0 0.4 2.6e-05 24.2 0.0 2.0 2 1 1 3 3 3 1 Aromatic acid exporter family member 2 FUSC PF04632.12 ETS78266.1 - 0.0022 16.6 21.4 0.086 11.4 14.0 2.8 3 0 0 3 3 3 2 Fusaric acid resistance protein family ArAE_1 PF06081.11 ETS78266.1 - 0.012 15.8 0.8 0.012 15.8 0.8 2.9 3 0 0 3 3 3 0 Aromatic acid exporter family member 1 Wzy_C PF04932.15 ETS78266.1 - 0.12 12.0 4.0 8.1 6.1 0.0 3.1 3 0 0 3 3 3 0 O-Antigen ligase DUF1097 PF06496.11 ETS78266.1 - 0.46 10.6 31.8 2.9 8.0 13.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1097) Fapy_DNA_glyco PF01149.24 ETS78268.1 - 1.3e-38 132.1 0.1 2.8e-38 131.1 0.1 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 ETS78268.1 - 1.5e-18 66.6 0.0 2.6e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 ETS78268.1 - 0.00013 20.9 0.0 0.017 13.9 0.0 2.2 2 0 0 2 2 2 2 Fibronectin-binding protein A N-terminus (FbpA) Pribosyl_synth PF14572.6 ETS78269.1 - 4.7e-41 140.8 0.3 1.9e-34 119.3 0.1 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 ETS78269.1 - 1.3e-32 112.1 0.0 3.7e-32 110.7 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 ETS78269.1 - 4.4e-12 45.8 0.2 8e-12 45.0 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TMP_2 PF06791.13 ETS78269.1 - 0.12 12.0 0.1 0.2 11.3 0.1 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein dsrm PF00035.26 ETS78270.1 - 8.2e-05 23.2 0.0 0.00012 22.7 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 ETS78270.1 - 0.0036 17.5 0.3 0.01 16.1 0.3 1.7 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 Arm-DNA-bind_1 PF09003.10 ETS78270.1 - 0.14 12.3 0.0 0.32 11.2 0.1 1.7 1 1 1 2 2 2 0 Bacteriophage lambda integrase, Arm DNA-binding domain NMO PF03060.15 ETS78271.1 - 4.5e-57 193.9 0.6 8.1e-56 189.8 0.6 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ETS78271.1 - 8.9e-14 51.2 0.0 2.6e-06 26.7 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ETS78271.1 - 0.00036 19.7 0.3 0.00065 18.8 0.3 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ETS78271.1 - 0.01 15.0 0.4 0.022 13.9 0.4 1.7 1 1 0 1 1 1 0 Conserved region in glutamate synthase His_biosynth PF00977.21 ETS78271.1 - 0.094 12.2 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein Cupin_2 PF07883.11 ETS78272.1 - 2.7e-15 55.8 0.2 1e-14 54.0 0.1 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 ETS78272.1 - 4e-06 26.5 0.0 5e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Cupin CENP-C_C PF11699.8 ETS78272.1 - 3.3e-05 24.0 0.0 5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Mif2/CENP-C like AraC_binding PF02311.19 ETS78272.1 - 0.00093 19.1 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 ETS78272.1 - 0.015 15.0 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Ndc80_HEC PF03801.13 ETS78275.1 - 1.7e-61 206.3 0.5 1.7e-61 206.3 0.5 2.2 3 0 0 3 3 3 1 HEC/Ndc80p family Spc7 PF08317.11 ETS78275.1 - 1.7e-05 23.9 45.4 0.00039 19.4 14.3 3.3 3 0 0 3 3 3 2 Spc7 kinetochore protein DUF5595 PF18077.1 ETS78275.1 - 0.00049 20.1 2.7 0.00049 20.1 2.7 6.0 5 2 1 6 6 6 1 Domain of unknown function (DUF5595) Fungal_TACC PF12709.7 ETS78275.1 - 0.018 15.5 0.2 0.018 15.5 0.2 5.8 3 2 2 5 5 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF1664 PF07889.12 ETS78275.1 - 0.027 14.5 0.5 0.027 14.5 0.5 4.6 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) FliJ PF02050.16 ETS78275.1 - 0.074 13.3 39.3 0.02 15.1 5.6 4.5 3 1 1 4 4 4 0 Flagellar FliJ protein DUF4407 PF14362.6 ETS78275.1 - 0.3 10.4 34.2 1.8 7.9 7.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 ETS78275.1 - 5.3 7.1 49.5 0.25 11.4 14.5 4.1 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein FlxA PF14282.6 ETS78275.1 - 5.9 7.0 24.8 11 6.0 0.9 4.4 3 1 1 4 4 4 0 FlxA-like protein HALZ PF02183.18 ETS78275.1 - 7.1 6.9 13.9 1.4 9.2 1.2 4.6 4 0 0 4 4 4 0 Homeobox associated leucine zipper MCPsignal PF00015.21 ETS78275.1 - 8 6.2 14.1 1.3 8.8 0.7 2.9 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Filament PF00038.21 ETS78275.1 - 8.6 5.8 52.3 7.5 6.0 25.0 3.5 2 2 0 2 2 2 0 Intermediate filament protein ESCRT-II PF05871.12 ETS78276.1 - 1e-52 178.1 0.2 1.5e-52 177.6 0.2 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit Cas9_Topo PF17894.1 ETS78276.1 - 0.15 12.2 0.0 0.38 10.8 0.0 1.6 2 0 0 2 2 2 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 PTCB-BRCT PF12738.7 ETS78277.1 - 3.2e-32 110.3 0.2 2.4e-18 65.9 0.2 4.7 4 0 0 4 4 4 4 twin BRCT domain RTT107_BRCT_5 PF16770.5 ETS78277.1 - 3.7e-31 107.0 0.0 5.7e-29 99.9 0.0 3.8 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 ETS78277.1 - 6.1e-30 103.5 0.3 1.1e-06 28.9 0.0 6.2 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ETS78277.1 - 1.3e-25 89.5 0.3 2e-06 28.1 0.0 6.1 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 ETS78277.1 - 8.7e-11 42.0 1.1 0.14 12.5 0.0 5.4 5 0 0 5 5 5 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 ETS78277.1 - 2.2e-08 34.1 0.0 0.34 11.0 0.0 4.7 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain MFS_1 PF07690.16 ETS78278.1 - 3.6e-36 124.8 26.2 3.6e-36 124.8 26.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Herpes_IE2_3 PF03361.14 ETS78279.1 - 0.12 12.3 0.1 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 Glyco_hydro_16 PF00722.21 ETS78280.1 - 1.8e-47 161.1 4.4 3.7e-47 160.1 4.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 UCH PF00443.29 ETS78281.1 - 1.5e-05 24.7 0.0 6.6e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ETS78281.1 - 0.00026 20.7 0.0 0.00059 19.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Caskin-Pro-rich PF16907.5 ETS78281.1 - 0.0032 17.9 15.6 0.0032 17.9 15.6 4.0 4 0 0 4 4 4 1 Proline rich region of Caskin proteins MFS_5 PF05631.14 ETS78282.1 - 4.6e-32 111.3 4.9 6.4e-32 110.8 4.9 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 ETS78282.1 - 2.5e-16 59.6 24.2 3.8e-16 59.0 24.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily F-box-like PF12937.7 ETS78284.1 - 0.00026 20.8 1.4 0.0013 18.6 0.1 2.5 2 0 0 2 2 2 1 F-box-like DUF4611 PF15387.6 ETS78284.1 - 0.13 12.5 1.8 0.24 11.6 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) AAA PF00004.29 ETS78286.1 - 2.5e-20 73.2 0.0 7.4e-20 71.7 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.12 ETS78286.1 - 4e-05 23.3 0.6 0.00096 18.8 0.2 2.4 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_16 PF13191.6 ETS78286.1 - 0.00023 21.6 5.7 0.00027 21.3 0.2 3.5 3 2 1 5 5 5 1 AAA ATPase domain AAA_5 PF07728.14 ETS78286.1 - 0.0018 18.3 0.0 0.0042 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ETS78286.1 - 0.01 16.1 1.1 0.07 13.4 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 ETS78286.1 - 0.056 13.2 0.0 0.056 13.2 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 ETS78286.1 - 0.066 13.5 1.6 0.58 10.4 0.2 2.4 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ETS78286.1 - 0.066 13.4 0.1 0.24 11.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 ETS78286.1 - 0.077 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain RuvB_N PF05496.12 ETS78286.1 - 0.077 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 ETS78286.1 - 0.083 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ETS78286.1 - 0.11 13.1 0.0 0.55 10.8 0.0 2.3 2 0 0 2 2 1 0 AAA domain Takusan PF04822.13 ETS78286.1 - 0.18 11.7 1.0 2 8.4 0.0 2.5 2 0 0 2 2 2 0 Takusan TCO89 PF10452.9 ETS78287.1 - 2.1e-05 23.7 1.3 0.0014 17.7 0.1 3.8 3 1 0 3 3 3 2 TORC1 subunit TCO89 Fungal_trans PF04082.18 ETS78289.1 - 6e-23 81.2 0.8 4.5e-22 78.4 0.8 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS78289.1 - 3e-05 24.0 5.2 5.4e-05 23.2 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NTP_transf_2 PF01909.23 ETS78289.1 - 0.086 13.1 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain MMACHC PF16690.5 ETS78290.1 - 0.045 13.4 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type C family Dna2 PF08696.11 ETS78291.1 - 5.6e-70 235.3 0.6 5.6e-70 235.3 0.6 1.9 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.6 ETS78291.1 - 1.6e-53 181.3 0.0 3.1e-53 180.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ETS78291.1 - 1.5e-33 116.7 1.7 4e-17 62.9 0.0 2.9 2 1 1 3 3 2 2 AAA domain AAA_30 PF13604.6 ETS78291.1 - 1.2e-13 51.2 0.0 3.2e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ETS78291.1 - 1.1e-12 48.6 0.1 2.7e-12 47.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 ETS78291.1 - 3e-09 37.2 0.5 8.5e-08 32.5 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 ETS78291.1 - 6.8e-07 29.3 0.8 0.34 10.6 0.1 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PDDEXK_1 PF12705.7 ETS78291.1 - 1.6e-06 28.2 0.0 3.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily UvrD-helicase PF00580.21 ETS78291.1 - 0.0001 21.9 0.0 0.00027 20.6 0.0 1.7 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 ETS78291.1 - 0.00015 21.7 0.0 0.00041 20.2 0.0 1.8 1 1 0 1 1 1 1 Helicase PIF1 PF05970.14 ETS78291.1 - 0.0006 19.1 0.0 0.003 16.8 0.0 2.0 1 1 0 1 1 1 1 PIF1-like helicase SRP54 PF00448.22 ETS78291.1 - 0.0006 19.5 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 ETS78291.1 - 0.0053 17.2 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 ETS78291.1 - 0.013 15.5 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 ETS78291.1 - 0.03 13.8 0.1 0.063 12.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 ETS78291.1 - 0.035 13.8 0.1 0.16 11.7 0.1 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain MobB PF03205.14 ETS78291.1 - 0.038 13.9 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.17 ETS78291.1 - 0.054 13.6 0.3 0.14 12.2 0.3 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain ResIII PF04851.15 ETS78291.1 - 0.063 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 ETS78291.1 - 0.083 12.5 0.0 0.29 10.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 ETS78291.1 - 0.091 12.7 0.2 0.25 11.3 0.2 1.6 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.9 ETS78291.1 - 0.097 11.9 0.0 0.21 10.8 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 ETS78291.1 - 0.14 12.6 0.1 0.44 11.0 0.1 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SGL PF08450.12 ETS78292.1 - 8.1e-24 84.5 0.7 1.8e-23 83.4 0.6 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 ETS78292.1 - 0.0001 22.4 0.0 0.00076 19.6 0.0 2.3 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 ETS78292.1 - 0.00031 20.9 0.0 0.0035 17.5 0.0 2.6 1 1 1 2 2 2 1 Arylesterase NHL PF01436.21 ETS78292.1 - 0.096 12.8 2.3 0.19 11.8 0.0 2.6 3 0 0 3 3 3 0 NHL repeat Rep_1B PF17873.1 ETS78292.1 - 6.7 6.7 5.8 7.4 6.5 2.3 2.7 3 0 0 3 3 3 0 Replicase polyprotein 1ab His_Phos_1 PF00300.22 ETS78293.1 - 9.7e-09 35.2 0.2 1.5e-07 31.3 0.2 2.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Not1 PF04054.15 ETS78294.1 - 1.1e-95 320.7 0.1 2.9e-95 319.3 0.1 1.8 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 ETS78294.1 - 3.7e-90 301.2 2.0 7e-90 300.3 2.0 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 ETS78294.1 - 8.2e-48 162.1 5.3 1.9e-47 160.9 5.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 ETS78294.1 - 1.5e-44 151.4 0.0 7.4e-44 149.2 0.0 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 ETS78294.1 - 9.9e-37 126.3 0.1 3.6e-36 124.5 0.1 2.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Tautomerase_3 PF14832.6 ETS78295.1 - 3.9e-43 146.9 0.3 1.3e-42 145.2 0.3 1.7 1 1 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme UPF0029 PF01205.19 ETS78296.1 - 1.4e-24 86.5 0.0 3.3e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Tctex-1 PF03645.13 ETS78296.1 - 0.064 13.5 0.4 0.15 12.3 0.4 1.6 1 0 0 1 1 1 0 Tctex-1 family Z1 PF10593.9 ETS78296.1 - 1.5 8.2 5.6 1.1 8.7 0.1 2.3 2 0 0 2 2 2 0 Z1 domain LRR_4 PF12799.7 ETS78297.1 - 1e-28 98.9 34.3 1.1e-05 25.7 0.4 8.8 5 1 4 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ETS78297.1 - 1.5e-27 95.1 40.0 3.6e-07 29.9 2.1 8.9 4 2 6 10 10 10 9 Leucine rich repeat LRR_1 PF00560.33 ETS78297.1 - 1.1e-06 28.3 24.3 12 6.9 0.2 11.3 11 1 1 12 12 12 2 Leucine Rich Repeat LRR_6 PF13516.6 ETS78297.1 - 1.5e-05 24.6 27.5 1.5 9.0 0.2 9.9 12 0 0 12 12 12 4 Leucine Rich repeat LRR_9 PF14580.6 ETS78297.1 - 0.0017 17.9 17.4 0.011 15.2 2.1 4.8 2 2 3 5 5 5 3 Leucine-rich repeat Phlebovirus_NSM PF07246.11 ETS78298.1 - 0.27 10.6 3.7 0.43 9.9 3.7 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M BAR_2 PF10455.9 ETS78298.1 - 0.34 10.0 10.5 0.97 8.5 10.5 1.7 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking CENP-F_leu_zip PF10473.9 ETS78298.1 - 1 9.4 13.7 2 8.4 13.7 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 ETS78298.1 - 6.2 7.3 11.3 3 8.3 1.3 2.6 2 0 0 2 2 2 0 Cell division protein ZapB Thiolase_N PF00108.23 ETS78299.1 - 5.9e-66 222.5 1.5 9.1e-66 221.9 1.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ETS78299.1 - 1.6e-40 137.6 0.2 3.4e-40 136.5 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain GATase PF00117.28 ETS78301.1 - 1.9e-07 31.0 0.0 2.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I BSMAP PF12280.8 ETS78302.1 - 0.023 14.9 0.2 0.042 14.1 0.2 1.4 1 1 0 1 1 1 0 Brain specific membrane anchored protein ABC2_membrane_5 PF13346.6 ETS78302.1 - 0.026 14.1 3.0 0.038 13.6 3.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Sporozoite_P67 PF05642.11 ETS78302.1 - 2.3 6.2 8.0 2.8 5.9 8.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Dicty_REP PF05086.12 ETS78302.1 - 4.6 5.1 7.5 6.1 4.7 7.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 ETS78302.1 - 6.2 4.8 8.8 7.3 4.6 8.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus MmgE_PrpD PF03972.14 ETS78304.1 - 9e-105 350.7 1.0 1.1e-104 350.4 1.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Iron_traffic PF04362.14 ETS78304.1 - 0.17 11.6 0.1 0.48 10.1 0.0 1.7 2 0 0 2 2 2 0 Bacterial Fe(2+) trafficking Kelch_4 PF13418.6 ETS78305.1 - 1.8e-23 82.2 1.3 1.6e-06 28.0 0.1 4.7 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 ETS78305.1 - 6.8e-22 77.2 5.2 2.2e-07 31.0 0.0 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 ETS78305.1 - 2.9e-17 62.0 0.2 6.9e-05 22.4 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 ETS78305.1 - 4.7e-16 58.4 0.6 0.00057 20.1 0.0 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 ETS78305.1 - 9.4e-14 50.8 0.8 0.00079 19.3 0.0 4.4 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.6 ETS78305.1 - 2.5e-13 49.7 0.3 0.016 15.2 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Meth_synt_2 PF01717.18 ETS78306.1 - 3.6e-06 26.5 0.0 0.00014 21.3 0.0 2.6 2 1 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 ETS78306.1 - 0.093 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain Epimerase PF01370.21 ETS78307.1 - 4.1e-05 23.2 0.0 5.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ISG65-75 PF11727.8 ETS78307.1 - 0.16 11.2 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein MFS_1 PF07690.16 ETS78308.1 - 2.6e-35 122.0 20.3 2.6e-35 122.0 20.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Arm PF00514.23 ETS78309.1 - 4.4e-05 23.4 2.4 1.7 8.8 0.0 5.5 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat KAP PF05804.12 ETS78309.1 - 0.033 12.4 0.0 0.31 9.1 0.0 2.1 2 0 0 2 2 2 0 Kinesin-associated protein (KAP) HEAT_2 PF13646.6 ETS78309.1 - 0.063 13.7 0.9 0.37 11.2 0.1 2.8 3 0 0 3 3 3 0 HEAT repeats DUF383 PF04063.14 ETS78309.1 - 0.084 12.5 0.0 0.32 10.6 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF383) HEAT PF02985.22 ETS78309.1 - 0.19 12.0 0.6 2.4 8.7 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat Ribosomal_L13e PF01294.18 ETS78310.1 - 1.3e-73 246.7 2.3 1.3e-73 246.7 2.3 1.3 2 0 0 2 2 2 1 Ribosomal protein L13e CAP59_mtransfer PF11735.8 ETS78311.1 - 6.2e-53 180.0 0.0 8e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Ank_2 PF12796.7 ETS78312.1 - 9.1e-12 45.4 0.0 0.0038 17.8 0.0 5.1 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS78312.1 - 1.5e-11 44.6 1.6 0.00044 20.7 0.0 7.8 5 3 4 10 10 10 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS78312.1 - 3.2e-10 39.3 3.8 0.93 10.3 0.0 8.0 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 ETS78312.1 - 0.00027 21.2 1.1 10 6.7 0.0 5.7 5 0 0 5 5 5 1 Ankyrin repeat F-box-like PF12937.7 ETS78313.1 - 2.7e-05 23.9 1.5 2.7e-05 23.9 1.5 2.3 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 ETS78313.1 - 0.14 12.0 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 F-box AA_permease_2 PF13520.6 ETS78315.1 - 7.5e-63 212.8 50.3 9.1e-63 212.5 50.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS78315.1 - 1.5e-28 99.7 45.2 2e-28 99.3 45.2 1.0 1 0 0 1 1 1 1 Amino acid permease OPT PF03169.15 ETS78316.1 - 7.9e-175 583.0 45.8 9e-175 582.8 45.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Chordopox_A13L PF05961.11 ETS78316.1 - 0.74 10.1 4.3 7.3 6.9 0.8 2.5 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Hira PF07569.11 ETS78317.1 - 1e-88 296.8 0.0 3.6e-88 295.0 0.0 2.0 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 ETS78317.1 - 1.6e-33 114.2 21.1 2.1e-06 28.3 0.0 8.7 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS78317.1 - 5.8e-18 65.0 0.3 0.011 16.0 0.0 6.3 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 ETS78317.1 - 2.5e-12 46.3 0.9 6.7e-12 45.0 0.9 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 ETS78317.1 - 2.6e-06 27.2 0.5 15 5.7 0.0 5.9 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 ETS78317.1 - 3.5e-06 26.2 0.2 0.28 10.1 0.0 5.4 3 1 3 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein GARP PF16731.5 ETS78317.1 - 0.011 15.5 6.1 0.019 14.6 6.1 1.3 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma IKI3 PF04762.12 ETS78317.1 - 0.19 9.7 0.2 0.82 7.6 0.0 2.0 3 0 0 3 3 3 0 IKI3 family TAF4 PF05236.14 ETS78317.1 - 0.3 10.8 7.5 0.6 9.8 7.5 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF2894 PF11445.8 ETS78317.1 - 1.6 9.2 4.8 3.3 8.2 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Glyco_transf_15 PF01793.16 ETS78318.1 - 1.3e-95 320.4 4.1 1.8e-95 319.9 4.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Sugar_tr PF00083.24 ETS78319.1 - 1.2e-79 268.4 21.9 1.5e-79 268.0 21.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS78319.1 - 8.7e-27 94.0 30.0 2.8e-26 92.3 30.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS78319.1 - 7.7e-08 31.2 2.4 1.3e-07 30.5 2.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3477 PF11963.8 ETS78319.1 - 0.27 10.4 0.5 1.7 7.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3477) DUF2929 PF11151.8 ETS78319.1 - 4 7.8 17.2 2.8 8.3 3.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) Clr5 PF14420.6 ETS78320.1 - 3.4e-11 43.2 0.2 6.4e-11 42.3 0.2 1.5 1 0 0 1 1 1 1 Clr5 domain Clr5 PF14420.6 ETS78321.1 - 0.18 12.0 0.7 0.44 10.8 0.7 1.7 1 0 0 1 1 1 0 Clr5 domain GAS PF13851.6 ETS78322.1 - 0.04 13.3 2.8 0.06 12.7 2.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Sortilin-Vps10 PF15902.5 ETS78323.1 - 8.4e-14 51.2 12.9 3e-05 23.0 2.0 5.4 4 2 0 5 5 5 4 Sortilin, neurotensin receptor 3, CBM_1 PF00734.18 ETS78323.1 - 1.3e-13 50.6 16.0 3.7e-13 49.2 16.0 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR_6 PF15899.5 ETS78323.1 - 0.00022 21.0 8.2 5.7 7.3 0.0 6.8 7 0 0 7 7 7 2 BNR-Asp box repeat BNR PF02012.20 ETS78323.1 - 0.0019 17.9 44.8 2.5 8.5 0.2 10.0 11 0 0 11 11 11 6 BNR/Asp-box repeat COX14 PF14880.6 ETS78324.1 - 2.4e-16 59.3 0.9 2.4e-16 59.3 0.9 1.9 2 0 0 2 2 2 1 Cytochrome oxidase c assembly DUF1515 PF07439.11 ETS78324.1 - 0.023 14.7 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) MSA-2c PF12238.8 ETS78324.1 - 1.3 8.9 5.3 0.89 9.5 2.7 2.0 2 0 0 2 2 2 0 Merozoite surface antigen 2c Lin-8 PF03353.15 ETS78324.1 - 1.8 8.1 4.8 0.29 10.7 0.8 1.6 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Herpes_UL31 PF02718.14 ETS78326.1 - 0.57 9.1 4.4 3.7 6.5 4.4 2.4 1 1 0 1 1 1 0 Herpesvirus UL31-like protein zf-LITAF-like PF10601.9 ETS78326.1 - 1 9.7 25.7 3.2 8.1 0.0 5.5 5 2 0 5 5 5 0 LITAF-like zinc ribbon domain Thioredoxin_8 PF13905.6 ETS78326.1 - 1.6 9.1 6.8 15 6.0 0.1 4.5 5 1 1 6 6 6 0 Thioredoxin-like CAP59_mtransfer PF11735.8 ETS78327.1 - 3.1e-66 223.5 0.0 4.3e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF4944 PF16302.5 ETS78327.1 - 0.036 14.1 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4944) GFA PF04828.14 ETS78328.1 - 2.9e-16 59.6 1.3 7.7e-07 29.4 0.1 3.0 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 ETS78328.1 - 3 7.6 17.1 0.64 9.7 0.9 3.9 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zf-RING_7 PF02591.15 ETS78328.1 - 4.3 7.6 0.0 4.3 7.6 0.0 3.8 4 0 0 4 4 4 0 C4-type zinc ribbon domain MRP-S31 PF15433.6 ETS78329.1 - 1 9.0 5.8 1.2 8.7 5.8 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 gag_pre-integrs PF13976.6 ETS78330.1 - 0.0029 17.4 0.5 0.0051 16.6 0.5 1.6 1 1 0 1 1 1 1 GAG-pre-integrase domain DEAD PF00270.29 ETS78332.1 - 1.7e-42 145.2 0.0 3.2e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS78332.1 - 5.3e-27 94.4 0.0 1.6e-26 92.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS78332.1 - 2.6e-05 24.3 0.0 5.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ETS78332.1 - 0.06 13.6 0.5 0.34 11.2 0.1 2.5 2 1 0 2 2 2 0 AAA domain FtsJ PF01728.19 ETS78333.1 - 7.1e-64 215.2 0.0 9.4e-64 214.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF5391 PF17369.2 ETS78334.1 - 0.7 9.9 6.3 0.12 12.4 0.8 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5391) Vps16_C PF04840.12 ETS78335.1 - 0.16 10.9 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Vps16, C-terminal region FAD_binding_3 PF01494.19 ETS78337.1 - 2.2e-18 66.6 0.7 3.3e-17 62.8 0.7 2.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS78337.1 - 8.8e-11 41.6 0.0 2.9e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS78337.1 - 7.2e-10 39.0 0.5 0.0004 20.1 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS78337.1 - 1.4e-06 27.3 0.0 0.016 14.0 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 ETS78337.1 - 1.3e-05 24.6 0.0 0.0021 17.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS78337.1 - 3e-05 24.1 0.2 0.00035 20.6 0.2 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 ETS78337.1 - 0.00012 21.6 0.4 0.0022 17.4 0.1 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS78337.1 - 0.00023 20.4 0.0 0.052 12.6 0.0 2.8 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 ETS78337.1 - 0.0014 19.1 0.0 0.18 12.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS78337.1 - 0.008 15.3 0.1 0.73 8.8 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 ETS78337.1 - 0.0089 14.9 0.1 2 7.2 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 ETS78337.1 - 0.019 15.2 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ETS78337.1 - 0.038 13.1 0.0 6.2 5.8 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.16 ETS78337.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF4566 PF15130.6 ETS78337.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) 3HCDH_N PF02737.18 ETS78337.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ETS78337.1 - 0.14 11.5 0.0 0.59 9.4 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Chlorophyllase2 PF12740.7 ETS78338.1 - 3e-05 23.1 0.0 4.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 ETS78338.1 - 6.3e-05 21.6 0.1 0.0021 16.7 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase PF07224.11 ETS78338.1 - 0.014 14.4 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Helo_like_N PF17111.5 ETS78339.1 - 2.1e-07 30.6 1.9 2.1e-07 30.6 1.9 1.7 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins DUF1664 PF07889.12 ETS78339.1 - 0.17 11.9 4.4 0.14 12.2 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 ETS78339.1 - 0.36 11.2 4.9 0.53 10.7 2.2 2.3 1 1 1 2 2 2 0 Syntaxin-like protein DUF2461 PF09365.10 ETS78340.1 - 1.1e-80 270.5 0.1 1.5e-80 270.1 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) AT_hook PF02178.19 ETS78340.1 - 4 7.6 24.1 3.9 7.7 4.8 3.6 3 0 0 3 3 3 0 AT hook motif MFS_1 PF07690.16 ETS78342.1 - 8.4e-23 80.9 47.3 5.6e-17 61.7 22.0 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS78342.1 - 0.0005 19.1 7.9 0.0005 19.1 7.9 3.5 3 1 1 4 4 4 2 Sugar (and other) transporter OATP PF03137.20 ETS78342.1 - 1.9 6.7 5.2 0.37 9.0 0.0 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2834 PF11196.8 ETS78343.1 - 0.24 11.8 13.2 0.082 13.3 1.6 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2834) Wzy_C PF04932.15 ETS78343.1 - 1.5 8.4 10.5 5.3 6.7 0.7 3.6 3 1 0 4 4 4 0 O-Antigen ligase Tox-REase-7 PF15649.6 ETS78344.1 - 0.065 13.6 0.8 2.4 8.6 0.1 3.0 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 7 NARP1 PF12569.8 ETS78344.1 - 1.2 8.0 5.9 2.3 7.0 5.9 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2433 PF10360.9 ETS78345.1 - 2.3e-48 163.4 0.0 3.6e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 ETS78345.1 - 0.00047 20.7 0.0 0.00085 19.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ETS78345.1 - 0.0027 17.9 0.0 0.0067 16.6 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ubie_methyltran PF01209.18 ETS78346.1 - 1.1e-76 257.2 0.0 1.3e-76 257.0 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 ETS78346.1 - 2.5e-15 56.9 0.0 8.7e-15 55.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS78346.1 - 1e-13 51.8 0.0 1.3e-12 48.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS78346.1 - 7.2e-12 45.9 0.0 1.2e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS78346.1 - 1.5e-11 44.3 0.0 2.1e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS78346.1 - 8.7e-07 28.9 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 ETS78346.1 - 0.19 11.6 0.0 0.4 10.5 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase Chromo_shadow PF01393.19 ETS78347.1 - 1.4e-23 82.7 2.1 9.6e-18 64.0 0.1 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 ETS78347.1 - 5.4e-13 48.6 1.3 5.4e-13 48.6 1.3 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-Di19 PF05605.12 ETS78348.1 - 0.02 15.2 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Kre28 PF17097.5 ETS78348.1 - 0.04 12.9 2.1 0.068 12.1 2.1 1.3 1 0 0 1 1 1 0 Spindle pole body component zf-C2H2_4 PF13894.6 ETS78348.1 - 0.044 14.6 0.1 0.11 13.4 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 ETS78348.1 - 0.048 13.6 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-ribbon_3 PF13248.6 ETS78348.1 - 0.083 12.3 0.3 0.15 11.5 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2 PF00096.26 ETS78348.1 - 0.1 13.1 0.1 0.22 12.0 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type RNA_polI_A14 PF08203.11 ETS78348.1 - 2.3 9.0 6.7 0.5 11.1 1.3 2.8 3 0 0 3 3 3 0 Yeast RNA polymerase I subunit RPA14 PHY PF00360.20 ETS78349.1 - 9e-28 96.8 0.0 2.3e-27 95.5 0.0 1.7 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 ETS78349.1 - 7.8e-20 71.5 0.1 1.4e-19 70.6 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ETS78349.1 - 2.5e-17 63.1 0.2 2.5e-16 59.8 0.0 2.5 2 1 0 2 2 2 1 Response regulator receiver domain GAF PF01590.26 ETS78349.1 - 1.3e-12 48.5 0.0 5e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 GAF domain HisKA PF00512.25 ETS78349.1 - 1.5e-11 44.2 0.6 3.7e-11 42.9 0.6 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 ETS78349.1 - 2.1e-08 34.8 0.0 7.2e-08 33.1 0.0 2.0 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 ETS78349.1 - 0.014 15.2 0.1 0.027 14.3 0.1 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase E1-E2_ATPase PF00122.20 ETS78350.1 - 8.3e-35 119.9 12.3 5.9e-24 84.6 0.2 4.2 5 0 0 5 5 5 2 E1-E2 ATPase Hydrolase PF00702.26 ETS78350.1 - 3.5e-19 69.9 0.0 9e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ETS78350.1 - 1.2e-09 37.7 0.0 3.2e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus 7TM_GPCR_Srsx PF10320.9 ETS78350.1 - 0.00075 18.9 0.5 1.4 8.3 0.1 2.5 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srsx Hydrolase_3 PF08282.12 ETS78350.1 - 0.0012 18.6 0.3 0.0026 17.5 0.2 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase YrvL PF14184.6 ETS78350.1 - 0.011 15.8 3.7 0.011 15.8 3.7 2.3 2 0 0 2 2 2 0 Regulatory protein YrvL GNVR PF13807.6 ETS78350.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase ApbA PF02558.16 ETS78351.1 - 1.2e-30 106.2 0.0 1.8e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 ETS78351.1 - 1.9e-27 95.9 0.0 5.5e-27 94.4 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal DIOX_N PF14226.6 ETS78352.1 - 2.8e-30 105.5 0.0 4.1e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS78352.1 - 1.2e-22 80.3 0.0 2.5e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF21 PF01595.20 ETS78353.1 - 9.1e-35 119.9 0.0 1.8e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 ETS78353.1 - 0.00082 19.8 1.2 0.24 11.9 0.0 2.9 3 0 0 3 3 3 2 CBS domain Lactonase PF10282.9 ETS78354.1 - 1.6e-17 63.9 0.0 2e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 ETS78354.1 - 0.098 12.2 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Zip PF02535.22 ETS78355.1 - 2.8e-50 171.5 2.4 5.8e-50 170.4 2.4 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter Cation_efflux PF01545.21 ETS78356.1 - 1e-24 87.4 16.5 1.3e-24 87.0 16.5 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ETS78356.1 - 5.4e-09 36.1 0.1 1.1e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DIM1 PF02966.16 ETS78356.1 - 0.13 12.1 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 Mitosis protein DIM1 DUF2104 PF09877.9 ETS78356.1 - 3.9 7.8 7.7 0.52 10.6 2.6 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) DUF423 PF04241.15 ETS78356.1 - 4.5 7.5 5.9 4.4 7.6 1.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF423) tRNA-synt_2 PF00152.20 ETS78358.1 - 1.8e-74 250.7 0.1 2.3e-74 250.3 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ETS78358.1 - 4.8e-13 48.9 0.1 8.9e-13 48.0 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ETS78358.1 - 5.6e-07 29.3 0.0 0.0067 15.9 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) COX15-CtaA PF02628.15 ETS78359.1 - 2e-111 372.2 7.2 2.5e-111 371.9 7.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Lipase_GDSL PF00657.22 ETS78360.1 - 0.09 12.7 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF3188 PF11384.8 ETS78360.1 - 0.18 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) HET PF06985.11 ETS78361.1 - 3.2e-11 43.8 9.1 3.3e-09 37.3 0.6 3.1 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Cupin_8 PF13621.6 ETS78362.1 - 5.7e-24 85.2 0.0 9.9e-24 84.4 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 ETS78362.1 - 9.7e-05 22.0 0.0 0.00045 19.8 0.0 1.9 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 ETS78362.1 - 0.0032 17.9 0.0 0.017 15.6 0.0 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 ETS78362.1 - 0.0074 16.0 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 Cupin domain CK_II_beta PF01214.18 ETS78363.1 - 1.5e-74 249.8 0.0 3.7e-74 248.5 0.0 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit PTPRCAP PF15713.5 ETS78363.1 - 0.18 12.1 9.4 8.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated RRN3 PF05327.11 ETS78363.1 - 0.19 10.2 2.3 0.28 9.7 2.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Myc_N PF01056.18 ETS78363.1 - 0.21 11.4 1.7 0.35 10.7 1.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Aldedh PF00171.22 ETS78364.1 - 1e-144 482.5 0.0 1.2e-144 482.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.18 ETS78365.1 - 1.3e-13 50.6 0.0 2.1e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS78365.1 - 7.5e-09 35.6 10.4 1.4e-08 34.7 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dala_Dala_lig_C PF07478.13 ETS78366.1 - 7.3e-11 42.0 0.0 1.1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 ETS78366.1 - 0.0038 16.7 0.0 0.023 14.2 0.0 2.0 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 ETS78366.1 - 0.004 16.8 0.1 0.019 14.5 0.1 2.0 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 ETS78366.1 - 0.02 14.7 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 ETS78366.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Dabb PF07876.12 ETS78367.1 - 4e-11 43.4 0.1 6.1e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF3198 PF11433.8 ETS78367.1 - 0.15 11.9 0.2 0.47 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) Amidohydro_2 PF04909.14 ETS78368.1 - 3.5e-23 82.8 0.0 4.9e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.16 ETS78369.1 - 5e-34 117.8 35.9 5e-34 117.8 35.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily TM_helix PF05552.12 ETS78369.1 - 0.035 14.1 1.3 0.19 11.7 0.2 2.5 2 0 0 2 2 2 0 Conserved TM helix HET PF06985.11 ETS78370.1 - 2.1e-33 115.7 7.9 9.6e-31 107.1 4.5 2.6 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) BNR PF02012.20 ETS78371.1 - 0.028 14.4 0.3 0.22 11.7 0.3 2.7 1 0 0 1 1 1 0 BNR/Asp-box repeat NmrA PF05368.13 ETS78372.1 - 3.5e-12 46.4 0.0 5.1e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ETS78372.1 - 2e-11 43.8 0.5 5.5e-09 35.8 0.2 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS78372.1 - 6.9e-11 42.4 0.4 2.6e-10 40.5 0.4 1.9 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 ETS78372.1 - 0.00012 22.1 0.4 0.00025 21.0 0.4 1.6 1 1 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 ETS78372.1 - 0.00022 21.6 0.0 0.0004 20.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 ETS78372.1 - 0.00069 18.8 0.3 0.0021 17.2 0.3 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ETS78372.1 - 0.0007 19.1 0.0 0.038 13.4 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ETS78372.1 - 0.00096 18.3 0.3 0.0017 17.5 0.3 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Shikimate_DH PF01488.20 ETS78372.1 - 0.0016 18.5 0.2 0.0045 17.0 0.1 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase LpxI_N PF17930.1 ETS78372.1 - 0.012 15.5 0.3 0.032 14.1 0.1 1.7 2 0 0 2 2 2 0 LpxI N-terminal domain F420_oxidored PF03807.17 ETS78372.1 - 0.018 15.6 0.0 0.048 14.2 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 ETS78372.1 - 0.022 14.9 1.6 0.38 10.9 0.1 2.4 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 ETS78372.1 - 0.04 14.2 0.1 0.088 13.1 0.1 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 ETS78372.1 - 0.1 12.7 0.5 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain TrkA_N PF02254.18 ETS78372.1 - 0.13 12.6 0.2 0.26 11.6 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain AIM24 PF01987.17 ETS78373.1 - 0.0011 18.8 0.3 0.0047 16.8 0.3 1.8 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 Kelch_3 PF13415.6 ETS78373.1 - 0.079 13.3 0.7 0.68 10.3 0.0 2.8 2 1 1 3 3 3 0 Galactose oxidase, central domain Glyco_hyd_65N_2 PF14498.6 ETS78374.1 - 3.2e-41 141.7 0.3 4.8e-41 141.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain MFS_1 PF07690.16 ETS78375.1 - 1.6e-16 60.2 47.5 2.5e-15 56.3 38.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS78375.1 - 2.2e-07 30.1 8.7 2.2e-07 30.1 8.7 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter Aldo_ket_red PF00248.21 ETS78376.1 - 7.2e-49 166.6 0.0 1.2e-48 165.8 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 ETS78376.1 - 3.3e-15 55.8 0.0 5.9e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.11 ETS78377.1 - 2.7e-30 105.6 0.0 5.9e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ldh_2 PF02615.14 ETS78380.1 - 4.2e-123 410.8 0.8 5.1e-123 410.5 0.8 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase PFO_beta_C PF12367.8 ETS78380.1 - 0.1 12.8 0.0 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal RraA-like PF03737.15 ETS78381.1 - 2.6e-33 115.3 0.0 3.2e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA Amidohydro_2 PF04909.14 ETS78382.1 - 3.7e-16 59.8 1.0 4.6e-16 59.4 1.0 1.1 1 0 0 1 1 1 1 Amidohydrolase F_bP_aldolase PF01116.20 ETS78383.1 - 4.7e-89 298.6 0.0 5.3e-89 298.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II An_peroxidase PF03098.15 ETS78384.1 - 9.7e-36 123.4 0.0 7.6e-25 87.5 0.0 3.1 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 ETS78384.1 - 0.011 14.5 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome P450 Pec_lyase_C PF00544.19 ETS78386.1 - 1.7e-17 63.7 7.9 2.2e-16 60.1 7.9 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 ETS78386.1 - 1.6e-08 34.6 12.1 4.1e-05 23.5 0.3 2.2 2 0 0 2 2 2 2 Right handed beta helix region DUF1996 PF09362.10 ETS78387.1 - 1.1e-81 274.2 3.3 1.6e-81 273.8 3.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) SipA_VBS PF17985.1 ETS78388.1 - 0.09 12.7 0.0 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 SipA vinculin binding site VPS13_C PF16909.5 ETS78388.1 - 2.5 7.8 3.9 1.5 8.5 1.7 1.7 1 1 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal dCMP_cyt_deam_1 PF00383.23 ETS78389.1 - 6.4e-09 35.6 0.0 1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ETS78389.1 - 4e-07 29.9 0.0 1.9e-06 27.7 0.0 2.0 1 1 1 2 2 2 1 MafB19-like deaminase Inv-AAD PF18785.1 ETS78389.1 - 0.024 14.5 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase Glyco_hydro_76 PF03663.14 ETS78390.1 - 2.9e-113 379.1 16.2 3.7e-113 378.8 16.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Tfb2 PF03849.14 ETS78393.1 - 1.3e-132 442.1 0.0 1.6e-132 441.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 ETS78393.1 - 4.1e-20 72.0 0.5 8.1e-20 71.0 0.5 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 ETS78393.1 - 1.2e-05 25.4 0.1 3e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MdcG PF10620.9 ETS78393.1 - 0.094 12.5 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG DUF1275 PF06912.11 ETS78394.1 - 1e-45 156.0 14.4 1.3e-45 155.7 14.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) PGG PF13962.6 ETS78394.1 - 0.023 14.5 1.5 0.063 13.1 1.5 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF3784 PF12650.7 ETS78394.1 - 1.4 9.2 4.9 0.65 10.2 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3784) MFS_1 PF07690.16 ETS78395.1 - 2.5e-32 112.2 26.3 2.5e-32 112.2 26.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.13 ETS78396.1 - 8e-93 311.2 3.9 9.1e-93 311.0 3.9 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 ETS78396.1 - 5e-05 22.0 1.0 7.4e-05 21.4 0.8 1.3 2 0 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_76 PF03663.14 ETS78396.1 - 0.0002 21.0 10.7 0.12 11.8 1.9 3.1 1 1 2 3 3 3 3 Glycosyl hydrolase family 76 SSF PF00474.17 ETS78397.1 - 3.5e-19 69.0 28.8 5e-19 68.4 28.8 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Anoctamin PF04547.12 ETS78398.1 - 8.4e-101 338.0 6.2 9.9e-101 337.8 6.2 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Pkinase PF00069.25 ETS78399.1 - 3.3e-55 187.3 0.0 5.4e-55 186.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS78399.1 - 1e-28 100.4 0.0 1.8e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS78399.1 - 9.8e-05 21.8 0.3 0.16 11.3 0.1 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 ETS78399.1 - 0.00049 19.5 0.2 0.0017 17.8 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 ETS78400.1 - 5.7e-15 54.9 0.0 8e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ETS78400.1 - 0.0049 16.4 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ETS78400.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif RRM_7 PF16367.5 ETS78400.1 - 0.21 11.8 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif DUF2457 PF10446.9 ETS78400.1 - 6.1 5.9 30.6 0.24 10.5 9.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Fasciclin PF02469.22 ETS78402.1 - 4.3e-33 114.3 0.0 8.4e-18 64.8 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain Glyco_hydro_16 PF00722.21 ETS78403.1 - 1.5e-15 57.1 1.3 2.5e-15 56.4 1.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TaqI_C PF12950.7 ETS78403.1 - 0.048 13.7 0.0 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 TaqI-like C-terminal specificity domain Glyco_trans_2_3 PF13632.6 ETS78404.1 - 9.6e-52 175.8 2.0 9.6e-52 175.8 2.0 2.1 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ETS78404.1 - 2.1e-06 27.7 0.0 9.1e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ETS78404.1 - 0.0026 17.3 0.0 0.0057 16.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 KAR PF15222.6 ETS78405.1 - 0.00039 20.7 0.1 0.00087 19.5 0.1 1.6 1 1 0 1 1 1 1 Kidney androgen-regulated FAM184 PF15665.5 ETS78405.1 - 0.00071 19.4 1.1 0.0032 17.3 0.3 1.9 2 0 0 2 2 2 1 Family with sequence similarity 184, A and B Nup54 PF13874.6 ETS78405.1 - 0.0016 18.6 2.5 0.0027 17.8 2.5 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 bZIP_1 PF00170.21 ETS78405.1 - 0.0039 17.3 5.0 0.0085 16.2 5.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor PriC PF07445.12 ETS78405.1 - 0.04 13.8 3.8 0.075 12.9 3.8 1.4 1 0 0 1 1 1 0 Primosomal replication protein priC LolB PF03550.14 ETS78405.1 - 0.085 12.9 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB bZIP_2 PF07716.15 ETS78405.1 - 6.7 6.9 11.0 0.9 9.7 4.2 2.2 2 0 0 2 2 2 0 Basic region leucine zipper SBF PF01758.16 ETS78406.1 - 9.8e-49 165.7 8.9 9.8e-49 165.7 8.9 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family Aldo_ket_red PF00248.21 ETS78408.1 - 4.4e-58 196.8 0.0 5.1e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OGFr_N PF04664.13 ETS78409.1 - 3.3e-15 56.2 0.0 5.5e-15 55.5 0.0 1.4 1 1 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region PAN_4 PF14295.6 ETS78411.1 - 2.6e-05 24.0 0.6 6.4e-05 22.8 0.6 1.7 1 0 0 1 1 1 1 PAN domain Otopetrin PF03189.13 ETS78411.1 - 0.018 13.9 2.4 3.2 6.5 2.8 2.0 1 1 1 2 2 2 0 Otopetrin MANEC PF07502.14 ETS78411.1 - 0.31 11.3 2.8 0.27 11.5 1.4 1.7 1 1 1 2 2 2 0 MANEC domain FSA_C PF10479.9 ETS78411.1 - 1.4 6.9 11.3 1.7 6.7 11.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus B277 PF17623.2 ETS78411.1 - 2.8 7.0 4.9 4.2 6.3 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF3427 PF11907.8 ETS78412.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3427) WSC PF01822.19 ETS78413.1 - 7.7e-68 224.7 61.5 1.5e-19 70.0 10.8 4.3 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.11 ETS78413.1 - 2.4e-24 85.9 0.0 1.5e-23 83.2 0.0 2.3 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 ETS78413.1 - 7.7e-24 83.8 0.5 1.8e-23 82.7 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 ETS78413.1 - 0.31 11.1 1.9 3.2 7.9 0.0 3.8 4 0 0 4 4 4 0 Kelch motif SIR2 PF02146.17 ETS78414.1 - 1.5e-53 181.3 0.0 2.1e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Cu-oxidase_2 PF07731.14 ETS78415.1 - 9.9e-40 135.4 3.9 3.8e-37 127.1 0.0 3.3 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ETS78415.1 - 3.5e-39 133.5 8.7 1.1e-38 131.9 5.7 2.9 2 1 1 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 ETS78415.1 - 5.2e-31 107.9 0.2 2.1e-30 105.9 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase FAD_binding_4 PF01565.23 ETS78416.1 - 3.4e-21 75.4 0.4 7e-21 74.4 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS78416.1 - 0.0016 18.5 1.6 0.0031 17.6 0.7 2.1 2 0 0 2 2 2 1 Berberine and berberine like Lipase_GDSL PF00657.22 ETS78417.1 - 1.9e-08 34.5 0.0 2.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ETS78417.1 - 3.4e-08 34.1 0.4 5.1e-08 33.5 0.4 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TetR_C_3 PF08362.11 ETS78417.1 - 0.21 11.5 0.2 14 5.6 0.1 2.2 2 0 0 2 2 2 0 YcdC-like protein, C-terminal region COesterase PF00135.28 ETS78420.1 - 1.6e-56 192.3 0.0 2.2e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Epimerase PF01370.21 ETS78421.1 - 4.1e-09 36.3 0.0 5.5e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ETS78421.1 - 0.0067 15.6 0.0 0.33 10.1 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 ETS78421.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase KR PF08659.10 ETS78421.1 - 0.036 14.0 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 KR domain adh_short PF00106.25 ETS78421.1 - 0.05 13.0 0.0 0.36 10.3 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase MFS_1 PF07690.16 ETS78422.1 - 1.8e-36 125.8 41.6 4.4e-36 124.5 41.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro2_C5 PF18565.1 ETS78423.1 - 2e-17 62.9 0.2 4.6e-17 61.7 0.2 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2 PF00703.21 ETS78423.1 - 7.5e-14 52.3 0.2 7.5e-14 52.3 0.2 2.9 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 ETS78423.1 - 2.7e-12 46.9 2.6 2.7e-12 46.9 2.6 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4982 PF16355.5 ETS78423.1 - 8.3e-12 44.9 2.6 2.1e-10 40.4 0.0 4.0 5 0 0 5 5 5 1 Domain of unknown function (DUF4982) F5_F8_type_C PF00754.25 ETS78423.1 - 4.4e-09 36.5 1.6 4.4e-09 36.5 1.6 2.3 2 0 0 2 2 2 1 F5/8 type C domain Invasin_D3 PF09134.10 ETS78423.1 - 0.0092 16.3 0.9 0.0092 16.3 0.9 3.6 3 1 1 4 4 4 1 Invasin, domain 3 MAM PF00629.23 ETS78423.1 - 0.27 11.1 1.7 1.6 8.6 0.0 3.0 4 0 0 4 4 4 0 MAM domain, meprin/A5/mu adh_short_C2 PF13561.6 ETS78424.1 - 1.8e-57 194.6 2.4 2.2e-57 194.3 2.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS78424.1 - 5.3e-43 146.7 4.5 6.5e-43 146.5 4.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS78424.1 - 4.2e-14 52.9 2.4 5.7e-14 52.4 2.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS78424.1 - 0.026 14.0 1.5 0.15 11.5 1.5 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.24 ETS78425.1 - 3.2e-99 332.8 22.2 3.7e-99 332.6 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS78425.1 - 9.4e-21 74.1 55.8 1.1e-19 70.6 28.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.12 ETS78425.1 - 0.15 11.8 1.4 0.37 10.5 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF697) ADH_N PF08240.12 ETS78426.1 - 1.9e-29 101.8 0.8 1.9e-29 101.8 0.8 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS78426.1 - 4e-23 81.8 0.7 7e-23 81.0 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS78426.1 - 1.9e-08 34.1 0.3 1.4e-07 31.3 0.3 2.0 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ETS78426.1 - 3.3e-06 28.2 0.0 2.1e-05 25.6 0.0 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 ETS78426.1 - 0.0047 17.6 0.1 0.0099 16.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 ETS78426.1 - 0.039 13.5 0.2 0.064 12.8 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FtsJ PF01728.19 ETS78426.1 - 0.096 12.8 0.5 0.21 11.7 0.1 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase 2-Hacid_dh_C PF02826.19 ETS78426.1 - 0.13 11.6 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 ETS78427.1 - 6.5e-07 28.5 4.4 0.00079 18.3 0.1 2.3 2 1 0 2 2 2 2 Fungal specific transcription factor domain MerB PF03243.15 ETS78428.1 - 4.4e-35 120.6 0.2 6.2e-35 120.1 0.2 1.2 1 0 0 1 1 1 1 Alkylmercury lyase HET PF06985.11 ETS78429.1 - 2.3e-20 73.5 0.0 3.3e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CorA PF01544.18 ETS78430.1 - 2e-07 30.6 4.2 3.6e-07 29.8 1.8 2.5 3 2 0 3 3 3 1 CorA-like Mg2+ transporter protein DUF4381 PF14316.6 ETS78430.1 - 0.035 14.3 0.6 0.072 13.3 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Osteopontin PF00865.18 ETS78430.1 - 0.093 12.2 0.6 0.15 11.5 0.6 1.2 1 0 0 1 1 1 0 Osteopontin AA_permease PF00324.21 ETS78431.1 - 3.6e-33 114.9 31.7 2.7e-22 79.0 17.1 2.2 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 ETS78431.1 - 4.5e-18 65.3 33.0 3.3e-15 55.9 15.4 2.3 2 1 0 2 2 2 2 Amino acid permease Pkinase PF00069.25 ETS78432.1 - 1e-13 51.2 0.0 3.2e-13 49.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS78432.1 - 8.2e-08 31.8 0.0 2e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Str_synth PF03088.16 ETS78432.1 - 0.029 14.5 0.0 0.082 13.0 0.0 1.7 1 0 0 1 1 1 0 Strictosidine synthase Alginate_lyase PF05426.12 ETS78435.1 - 3.2e-16 59.7 2.7 3.2e-16 59.7 2.7 2.0 2 1 0 2 2 2 1 Alginate lyase Glyco_hydro_28 PF00295.17 ETS78436.1 - 0.00011 21.4 3.0 0.00026 20.2 0.3 2.4 1 1 1 2 2 2 1 Glycosyl hydrolases family 28 PrpF PF04303.13 ETS78437.1 - 3.3e-87 292.9 0.1 4.8e-84 282.4 0.2 2.0 2 0 0 2 2 2 2 PrpF protein Fungal_trans PF04082.18 ETS78440.1 - 5.7e-20 71.5 0.0 1.1e-19 70.5 0.0 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS78440.1 - 2e-10 40.6 9.8 3.1e-10 40.0 9.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RRPl_C4 PF17026.5 ETS78440.1 - 0.038 14.1 2.7 0.06 13.4 2.7 1.3 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Opy2 PF09463.10 ETS78440.1 - 0.17 12.3 3.2 0.36 11.2 3.2 1.5 1 0 0 1 1 1 0 Opy2 protein p450 PF00067.22 ETS78441.1 - 2.4e-47 161.8 0.0 2.6e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 ETS78442.1 - 7.2e-122 407.5 23.5 8.3e-122 407.3 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS78442.1 - 3.4e-27 95.3 29.6 3.4e-27 95.3 29.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 ETS78443.1 - 1.5e-29 103.1 47.9 3e-28 98.8 47.9 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS78443.1 - 5.8e-05 22.1 18.0 0.00021 20.3 12.6 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter DUF5337 PF17272.2 ETS78443.1 - 0.13 12.1 5.8 0.44 10.4 5.8 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5337) Glyco_transf_90 PF05686.12 ETS78444.1 - 1.1e-12 47.6 0.3 1.2e-11 44.1 0.0 2.6 3 1 0 3 3 3 1 Glycosyl transferase family 90 Zn_clus PF00172.18 ETS78447.1 - 2.7e-06 27.4 8.9 6.1e-06 26.3 8.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ETS78450.1 - 1.2e-12 47.5 4.1 1.3e-12 47.3 4.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS78450.1 - 2.6e-05 23.3 1.5 3.2e-05 23.0 1.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS78451.1 - 1.4e-05 24.3 17.2 1.5e-05 24.1 17.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Iso_dh PF00180.20 ETS78452.1 - 1.1e-73 248.4 0.0 1.8e-73 247.7 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aconitase PF00330.20 ETS78452.1 - 2.4e-68 231.2 0.0 7.2e-67 226.4 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ETS78452.1 - 2.8e-12 47.1 0.2 2.2e-11 44.2 0.1 2.5 2 1 0 2 2 2 1 Aconitase C-terminal domain COesterase PF00135.28 ETS78453.1 - 4.6e-78 263.3 0.0 6.2e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS78453.1 - 0.00055 19.8 0.5 0.0092 15.9 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold HET PF06985.11 ETS78454.1 - 1.4e-28 100.0 0.6 2.5e-28 99.3 0.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) G-alpha PF00503.20 ETS78455.1 - 3.1e-60 204.2 0.1 8.5e-60 202.8 0.1 1.7 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ETS78455.1 - 7.5e-10 38.5 0.3 9.8e-07 28.4 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ETS78455.1 - 0.0015 18.6 0.0 1.8 8.7 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ETS78455.1 - 0.0019 17.9 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 ETS78455.1 - 0.021 14.2 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 ETS78455.1 - 0.025 15.1 0.0 0.6 10.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 ETS78455.1 - 0.035 14.6 0.1 0.16 12.4 0.0 2.1 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 ETS78455.1 - 0.047 13.0 0.2 0.28 10.5 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 ETS78455.1 - 0.051 13.8 0.3 0.46 10.7 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NRBF2 PF08961.10 ETS78455.1 - 0.054 13.1 0.3 0.35 10.4 0.1 2.1 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator DUF815 PF05673.13 ETS78455.1 - 0.065 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 ETS78455.1 - 0.074 13.4 0.0 0.96 9.8 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_21 PF13304.6 ETS78455.1 - 0.089 12.6 0.3 11 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AA_permease_2 PF13520.6 ETS78457.1 - 1.7e-58 198.5 55.6 2.2e-58 198.1 55.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS78457.1 - 7.4e-15 54.5 41.2 1.1e-14 54.0 41.2 1.2 1 0 0 1 1 1 1 Amino acid permease GFA PF04828.14 ETS78458.1 - 2.5e-12 47.0 2.8 4.1e-12 46.3 2.8 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_28 PF00295.17 ETS78459.1 - 2.3e-50 171.5 10.8 3.5e-50 170.9 10.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF4369 PF14289.6 ETS78459.1 - 0.083 13.4 0.2 0.22 12.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4369) Pectinesterase PF01095.19 ETS78460.1 - 4.5e-25 88.0 1.0 1.2e-18 66.8 0.3 2.1 2 0 0 2 2 2 2 Pectinesterase Pectate_lyase_3 PF12708.7 ETS78460.1 - 0.036 13.9 7.0 0.074 12.9 7.0 1.4 1 0 0 1 1 1 0 Pectate lyase superfamily protein DNA_methylase PF00145.17 ETS78461.1 - 4.4e-38 131.5 0.4 2.1e-27 96.4 0.0 2.5 2 1 0 3 3 3 2 C-5 cytosine-specific DNA methylase Methyltransf_15 PF09445.10 ETS78461.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Glyco_hydro_35 PF01301.19 ETS78462.1 - 1.4e-93 314.0 0.0 1.9e-93 313.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 ETS78462.1 - 2.9e-56 188.9 0.3 4.3e-30 104.6 0.0 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 ETS78462.1 - 8.4e-52 175.6 0.4 1.6e-51 174.7 0.4 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 ETS78462.1 - 1.8e-13 49.9 0.0 8.3e-13 47.7 0.0 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 ETS78462.1 - 0.019 14.4 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Amidohydro_1 PF01979.20 ETS78463.1 - 7.4e-23 81.4 0.0 5.3e-22 78.6 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS78463.1 - 1.7e-09 37.7 0.9 3.4e-06 26.8 0.1 3.1 3 0 0 3 3 3 3 Amidohydrolase family Methyltransf_32 PF13679.6 ETS78464.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NFACT-C PF11923.8 ETS78465.1 - 1.2e-39 134.5 1.2 1.2e-39 134.5 1.2 3.2 2 1 0 2 2 2 1 NFACT protein C-terminal domain FbpA PF05833.11 ETS78465.1 - 4.6e-35 121.3 12.7 4.6e-35 121.3 12.7 2.6 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 ETS78465.1 - 1.3e-32 112.6 0.0 6.4e-32 110.4 0.0 2.3 2 0 0 2 2 2 1 NFACT protein RNA binding domain eIF-5a PF01287.20 ETS78466.1 - 5.8e-07 29.5 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DUF4717 PF15838.5 ETS78466.1 - 0.17 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4717) Peptidase_C1_2 PF03051.15 ETS78467.1 - 1e-149 499.1 0.0 1.3e-149 498.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 ETS78467.1 - 3.1e-07 30.7 0.0 0.0019 18.3 0.0 2.4 3 0 0 3 3 3 2 Papain family cysteine protease HET PF06985.11 ETS78471.1 - 1.5e-28 100.0 1.3 1.1e-26 93.9 1.3 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pectate_lyase PF03211.13 ETS78472.1 - 2.7e-86 288.3 10.3 3.2e-86 288.0 10.3 1.1 1 0 0 1 1 1 1 Pectate lyase Glyco_hydro_3_C PF01915.22 ETS78474.1 - 1.2e-54 185.4 0.0 4.4e-54 183.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS78474.1 - 6e-50 170.4 0.0 9.5e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS78474.1 - 4.1e-19 68.5 0.0 1.1e-18 67.1 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 ETS78474.1 - 2.6e-05 24.1 0.0 5.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Aldedh PF00171.22 ETS78475.1 - 6.8e-117 390.8 0.0 9.4e-117 390.3 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PhoLip_ATPase_C PF16212.5 ETS78476.1 - 5.5e-78 262.2 27.5 5.5e-78 262.2 27.5 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ETS78476.1 - 4.4e-19 67.9 0.6 1.1e-18 66.6 0.6 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ETS78476.1 - 2.9e-13 49.7 0.0 1.9e-12 47.1 0.0 2.3 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ETS78476.1 - 8.6e-11 42.5 6.8 6.5e-07 29.8 3.1 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ETS78476.1 - 0.03 13.9 0.0 0.03 13.9 0.0 2.2 3 0 0 3 3 3 0 E1-E2 ATPase Hydrolase_3 PF08282.12 ETS78476.1 - 0.071 12.8 0.6 0.16 11.7 0.6 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MIP-T3_C PF17749.1 ETS78476.1 - 1.8 8.5 5.3 16 5.4 0.3 2.5 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Cmyb_C PF09316.10 ETS78477.1 - 0.075 12.7 1.0 0.18 11.5 0.1 2.0 2 0 0 2 2 2 0 C-myb, C-terminal vATP-synt_E PF01991.18 ETS78478.1 - 2.4e-66 223.0 11.4 2.8e-66 222.7 11.4 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit TTc_toxin_rep PF18807.1 ETS78478.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Tripartite Tc toxins repeat SurA_N_3 PF13624.6 ETS78478.1 - 0.17 11.7 5.6 1.6 8.5 1.3 2.3 1 1 1 2 2 2 0 SurA N-terminal domain Spore_II_R PF09551.10 ETS78478.1 - 6.6 7.2 11.4 7.8 7.0 6.2 2.1 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) SecA_SW PF07516.13 ETS78478.1 - 6.9 6.7 9.2 5.6 7.0 0.1 2.1 1 1 1 2 2 2 0 SecA Wing and Scaffold domain Mg_trans_NIPA PF05653.14 ETS78479.1 - 1.2e-15 57.4 7.0 1.8e-15 56.8 7.0 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ETS78479.1 - 0.00089 19.4 0.3 0.00089 19.4 0.3 2.7 2 1 0 2 2 2 1 EamA-like transporter family PUNUT PF16913.5 ETS78479.1 - 0.001 18.3 10.6 0.0015 17.8 7.0 2.6 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport DEAD PF00270.29 ETS78481.1 - 6.6e-45 153.0 0.0 1.2e-44 152.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS78481.1 - 9.5e-27 93.5 0.0 2e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UTP25 PF06862.12 ETS78481.1 - 0.013 14.3 0.1 2.6 6.7 0.0 2.7 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SecA_DEAD PF07517.14 ETS78481.1 - 0.15 11.3 0.1 17 4.6 0.0 2.2 2 0 0 2 2 2 0 SecA DEAD-like domain Ipi1_N PF12333.8 ETS78482.1 - 1.1e-22 80.6 0.0 3.9e-22 78.8 0.0 2.0 2 1 1 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Robl_LC7 PF03259.17 ETS78483.1 - 4.4e-10 39.2 0.0 1.4e-07 31.2 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain LAMTOR5 PF16672.5 ETS78483.1 - 0.083 12.8 0.0 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 Ragulator complex protein LAMTOR5 DUF2944 PF11161.8 ETS78483.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) CorA PF01544.18 ETS78486.1 - 2.2e-12 46.9 0.7 2.2e-12 46.9 0.7 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Fzo_mitofusin PF04799.13 ETS78486.1 - 0.24 10.9 1.5 0.43 10.1 0.5 1.8 2 0 0 2 2 2 0 fzo-like conserved region Cyclin PF08613.11 ETS78487.1 - 3.4e-06 27.5 1.6 3.4e-06 27.5 1.6 2.6 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 ETS78487.1 - 0.002 17.9 0.2 0.0043 16.8 0.2 1.6 1 1 0 1 1 1 1 Cyclin, N-terminal domain DEAD PF00270.29 ETS78488.1 - 1.3e-38 132.5 0.1 2.3e-38 131.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS78488.1 - 1.8e-24 86.2 0.4 4.3e-23 81.8 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS78488.1 - 9.1e-09 35.5 0.0 2.7e-08 34.0 0.0 1.7 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 ETS78488.1 - 0.00049 19.7 0.0 0.0007 19.2 0.0 1.1 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF4844 PF16133.5 ETS78488.1 - 0.004 17.7 1.1 0.0094 16.5 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4844) CMS1 PF14617.6 ETS78488.1 - 0.052 12.9 0.2 0.23 10.8 0.1 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Pyr_redox_3 PF13738.6 ETS78489.1 - 2.6e-17 63.0 0.0 5.1e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ETS78489.1 - 1.5e-16 59.9 0.0 7.1e-15 54.4 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ETS78489.1 - 4.2e-13 49.2 0.0 9e-12 44.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS78489.1 - 1.2e-12 47.7 0.1 9.5e-11 41.4 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 ETS78489.1 - 5.4e-06 25.8 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 ETS78489.1 - 6.6e-05 23.1 0.0 0.00021 21.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS78489.1 - 0.00021 21.3 0.1 0.011 15.8 0.2 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 ETS78489.1 - 0.00041 19.7 0.0 0.041 13.2 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 ETS78489.1 - 0.0022 16.7 0.0 1.3 7.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 ETS78489.1 - 0.0027 17.3 0.0 0.041 13.5 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ETS78489.1 - 0.0044 16.4 0.0 0.0078 15.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF4147 PF13660.6 ETS78489.1 - 0.0088 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4147) Pyr_redox PF00070.27 ETS78489.1 - 0.018 15.6 0.4 13 6.4 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 ETS78489.1 - 0.02 13.5 0.0 2.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.12 ETS78489.1 - 0.021 13.9 0.2 0.038 13.1 0.2 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 ETS78489.1 - 0.023 13.9 0.1 0.29 10.3 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 ETS78489.1 - 0.031 13.4 0.1 0.057 12.5 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ETS78489.1 - 0.032 13.3 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.16 ETS78490.1 - 7.8e-43 146.7 39.0 7.8e-43 146.7 39.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HOK_GEF PF01848.16 ETS78490.1 - 1.4 8.4 7.6 0.055 12.9 1.4 1.9 2 0 0 2 2 2 0 Hok/gef family Abhydrolase_3 PF07859.13 ETS78491.1 - 6.9e-43 147.0 0.0 8.9e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS78491.1 - 0.0018 17.3 0.0 0.0037 16.2 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 ETS78491.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 ETS78492.1 - 1.4e-19 70.8 0.0 2e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS78492.1 - 3.8e-15 55.6 0.0 5.6e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Rpr2 PF04032.16 ETS78493.1 - 4.7e-27 94.1 0.6 7.5e-27 93.5 0.6 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain UDPGT PF00201.18 ETS78494.1 - 6.3e-05 22.0 0.0 8.1e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 ETS78494.1 - 0.044 13.8 0.0 0.1 12.7 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain ApbA PF02558.16 ETS78495.1 - 4.8e-27 94.5 0.0 8.9e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 ETS78495.1 - 6.5e-20 71.6 0.0 9.9e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.11 ETS78496.1 - 1.1e-20 73.7 4.2 1.4e-20 73.3 4.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like LPP PF04728.13 ETS78496.1 - 0.15 12.4 0.3 0.24 11.8 0.3 1.2 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Amidase PF01425.21 ETS78497.1 - 2.4e-70 237.8 0.0 9e-70 235.9 0.0 1.7 1 1 0 1 1 1 1 Amidase Yae1_N PF09811.9 ETS78498.1 - 1.2e-13 50.5 2.1 2.9e-13 49.3 2.1 1.7 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF2524 PF10732.9 ETS78498.1 - 0.015 15.6 0.0 0.23 11.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) CENP-O PF09496.10 ETS78500.1 - 2.1e-68 230.5 0.1 2.1e-68 230.5 0.1 1.7 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component DUF5641 PF18701.1 ETS78500.1 - 0.0028 17.8 0.1 0.0056 16.8 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5641) Acatn PF13000.7 ETS78501.1 - 5.5e-167 556.6 17.7 1.9e-83 280.9 7.7 3.2 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DUF4449 PF14613.6 ETS78502.1 - 0.0028 17.8 0.0 0.0028 17.8 0.0 2.5 4 0 0 4 4 4 1 Protein of unknown function (DUF4449) DUF445 PF04286.12 ETS78502.1 - 0.02 14.7 7.2 0.069 13.0 7.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Ku_PK_bind PF08785.11 ETS78502.1 - 0.15 12.2 1.6 0.57 10.3 0.1 2.5 2 0 0 2 2 2 0 Ku C terminal domain like MFS_1 PF07690.16 ETS78503.1 - 9.1e-41 139.9 48.3 8.3e-40 136.8 46.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily VCBS PF13517.6 ETS78505.1 - 8.9e-32 109.5 64.5 1.6e-11 44.6 2.2 8.1 3 2 4 7 7 7 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 ETS78505.1 - 3.3e-10 40.6 0.9 5.8e-10 39.8 0.3 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS78505.1 - 6.6e-06 26.2 0.1 1.3e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 ETS78505.1 - 3.8e-05 23.1 8.3 5 6.5 0.0 6.4 6 1 1 7 7 7 3 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_3 PF14606.6 ETS78505.1 - 0.00095 19.3 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FG-GAP PF01839.23 ETS78505.1 - 0.033 14.3 36.6 0.89 9.8 1.2 6.6 6 0 0 6 6 6 0 FG-GAP repeat NAD_binding_4 PF07993.12 ETS78506.1 - 1.8e-33 115.8 0.0 3.2e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 ETS78506.1 - 6.3e-26 90.9 0.0 1.4e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 ETS78506.1 - 2e-09 37.7 0.0 6.7e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.21 ETS78506.1 - 9.2e-09 35.1 0.0 1.8e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ETS78506.1 - 0.008 16.1 0.1 0.076 12.9 0.1 2.5 1 1 0 1 1 1 1 KR domain DFP PF04127.15 ETS78507.1 - 1.9e-13 50.6 0.0 1.4e-05 25.0 0.0 3.3 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein CFEM PF05730.11 ETS78508.1 - 0.043 13.9 8.0 0.088 12.9 8.0 1.5 1 0 0 1 1 1 0 CFEM domain Pkinase PF00069.25 ETS78509.1 - 1.4e-60 204.9 0.0 1.5e-59 201.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS78509.1 - 2.3e-28 99.2 0.5 4.2e-20 72.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 ETS78509.1 - 3.6e-05 24.4 0.9 3.6e-05 24.4 0.9 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 ETS78509.1 - 0.0024 17.2 0.1 0.011 15.1 0.0 2.1 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 ETS78509.1 - 0.0029 17.5 0.5 0.094 12.6 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 ETS78509.1 - 0.028 13.8 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ETS78509.1 - 0.032 13.2 0.0 0.057 12.4 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Wbp11 PF09429.10 ETS78510.1 - 6e-24 84.3 14.9 1.6e-23 82.9 14.9 1.8 1 0 0 1 1 1 1 WW domain binding protein 11 Lipoprotein_7 PF01540.16 ETS78510.1 - 0.022 14.1 4.6 0.031 13.6 4.6 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein HDV_ag PF01517.18 ETS78510.1 - 0.024 14.5 0.5 0.024 14.5 0.5 2.4 1 1 1 2 2 2 0 Hepatitis delta virus delta antigen DUF1451 PF07295.11 ETS78510.1 - 0.028 14.4 0.4 0.054 13.5 0.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain MFS_1 PF07690.16 ETS78511.1 - 7.4e-37 127.1 62.2 2.2e-36 125.5 40.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS78511.1 - 2.9e-09 36.3 35.8 1.1e-05 24.6 12.1 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter Git3 PF11710.8 ETS78512.1 - 2.2e-11 43.9 7.3 1e-10 41.8 7.3 2.1 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 zf-C3H1 PF10650.9 ETS78513.1 - 2e-06 27.4 3.7 3e-06 26.8 3.7 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain zf-CCCH PF00642.24 ETS78513.1 - 0.00028 20.7 0.3 0.00046 20.0 0.3 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ETS78513.1 - 0.26 11.1 0.2 0.4 10.6 0.2 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ETS78513.1 - 0.29 11.3 0.4 0.45 10.6 0.4 1.3 1 0 0 1 1 1 0 Zinc finger domain KIAA1430 PF13879.6 ETS78513.1 - 1.5 9.6 0.0 1.5 9.6 0.0 3.3 4 0 0 4 4 4 0 KIAA1430 homologue Myosin_head PF00063.21 ETS78514.1 - 4e-267 887.9 0.0 1.1e-266 886.4 0.0 1.8 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 ETS78514.1 - 1.9e-12 46.8 0.2 4.9e-12 45.5 0.2 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 ETS78514.1 - 8.6e-08 30.5 61.4 2.7e-07 28.9 26.1 8.5 2 2 4 7 7 7 5 Myosin tail RsgA_GTPase PF03193.16 ETS78514.1 - 0.016 15.1 0.1 0.11 12.4 0.1 2.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 ETS78514.1 - 0.16 12.2 0.0 0.16 12.2 0.0 5.0 4 0 0 4 4 4 0 AAA domain adh_short PF00106.25 ETS78515.1 - 1.2e-27 96.6 0.0 1.4e-26 93.2 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS78515.1 - 9.3e-19 67.9 0.0 1.6e-13 50.8 0.0 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF3176 PF11374.8 ETS78516.1 - 2e-30 105.1 0.6 2e-30 105.1 0.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) MMR_HSR1 PF01926.23 ETS78517.1 - 2.4e-13 50.1 0.0 4.6e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ETS78517.1 - 0.0022 17.5 0.1 0.0043 16.6 0.1 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ETS78517.1 - 0.0069 16.5 0.1 0.39 10.7 0.0 2.5 1 1 0 2 2 2 1 Dynamin family IIGP PF05049.13 ETS78517.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 ETS78517.1 - 0.012 15.5 0.5 0.088 12.7 0.3 2.4 1 1 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 ETS78517.1 - 0.03 14.0 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.21 ETS78517.1 - 0.092 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family GST_C PF00043.25 ETS78517.1 - 0.094 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Amidase PF01425.21 ETS78519.1 - 9.6e-53 179.7 0.0 2.9e-48 165.0 0.0 2.2 2 0 0 2 2 2 2 Amidase RRM_1 PF00076.22 ETS78520.1 - 2e-12 46.7 0.0 3.7e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 ETS78520.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain zf-C2H2_jaz PF12171.8 ETS78521.1 - 0.028 14.7 1.3 0.085 13.2 1.3 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Bac_luciferase PF00296.20 ETS78524.1 - 4.7e-52 177.4 0.2 6.8e-52 176.8 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 ETS78525.1 - 6.2e-29 101.0 23.4 5.1e-28 98.0 24.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5336 PF17270.2 ETS78525.1 - 0.38 10.4 5.8 5 6.7 0.0 2.9 2 1 0 3 3 3 0 Family of unknown function (DUF5336) Phage_holin_2_4 PF16082.5 ETS78525.1 - 0.5 10.1 0.0 0.5 10.1 0.0 2.8 3 1 0 3 3 3 0 Bacteriophage holin family, superfamily II-like PHD PF00628.29 ETS78527.1 - 2.3e-08 33.8 1.2 5.7e-08 32.5 1.2 1.7 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 ETS78527.1 - 0.0053 16.8 0.7 0.012 15.7 0.7 1.6 1 0 0 1 1 1 1 CW-type Zinc Finger PHD_2 PF13831.6 ETS78527.1 - 0.035 13.7 2.5 0.058 13.0 2.5 1.4 1 0 0 1 1 1 0 PHD-finger Pyridox_ox_2 PF12900.7 ETS78528.1 - 9.1e-31 106.7 0.0 1.6e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Oxysterol_BP PF01237.18 ETS78529.1 - 2.3e-131 438.0 1.8 3.8e-131 437.4 0.0 2.0 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.7 ETS78529.1 - 2.2e-18 66.6 3.4 8.7e-10 39.1 0.3 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS78529.1 - 3.9e-14 52.5 0.3 4e-07 30.2 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ETS78529.1 - 6.7e-13 48.4 1.5 0.0012 19.2 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.29 ETS78529.1 - 1.4e-12 48.0 0.8 2.8e-12 47.0 0.8 1.6 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 ETS78529.1 - 5.1e-11 42.9 0.1 2.3e-07 31.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS78529.1 - 7.5e-11 41.3 0.1 0.0011 19.2 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.6 ETS78529.1 - 3.1e-08 33.8 1.6 8.6e-08 32.4 1.6 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Shigella_OspC PF06128.11 ETS78529.1 - 0.024 14.4 0.1 2.9 7.6 0.1 2.2 2 0 0 2 2 2 0 Shigella flexneri OspC protein Carboxyl_trans PF01039.22 ETS78530.1 - 7e-136 453.7 0.0 9.5e-136 453.3 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 ETS78530.1 - 0.0019 17.7 0.1 1.6 8.2 0.0 2.4 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) NAD_binding_3 PF03447.16 ETS78530.1 - 0.11 13.1 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Acyl-CoA_dh_1 PF00441.24 ETS78531.1 - 1e-41 142.7 0.9 1.6e-41 142.0 0.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ETS78531.1 - 1.5e-30 106.1 0.0 3.8e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ETS78531.1 - 1.1e-26 92.8 0.2 2.3e-26 91.8 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ETS78531.1 - 4.1e-13 49.8 0.1 7.9e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ETS78531.1 - 0.00058 19.6 0.1 0.0014 18.4 0.1 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal adh_short_C2 PF13561.6 ETS78532.1 - 3.2e-54 184.0 0.0 4.5e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS78532.1 - 3.1e-38 131.2 0.1 4.1e-38 130.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS78532.1 - 5.5e-13 49.2 0.1 7.9e-13 48.7 0.1 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ETS78532.1 - 0.15 11.9 0.2 0.41 10.5 0.3 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1752 PF08550.10 ETS78533.1 - 0.055 13.3 0.3 0.12 12.2 0.3 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) ThuA PF06283.11 ETS78534.1 - 4.4e-66 223.1 0.1 4.9e-66 222.9 0.1 1.0 1 0 0 1 1 1 1 Trehalose utilisation LBP_M PF17385.2 ETS78534.1 - 0.0053 16.3 0.1 0.011 15.2 0.1 1.6 1 1 0 1 1 1 1 Lacto-N-biose phosphorylase central domain DUF4159 PF13709.6 ETS78534.1 - 0.02 14.3 0.0 0.041 13.3 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4159) TPR_12 PF13424.6 ETS78535.1 - 6e-35 119.4 16.2 3.4e-08 33.7 1.3 5.1 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 ETS78535.1 - 8.7e-35 117.6 12.7 3.2e-07 30.0 1.6 8.6 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS78535.1 - 4.8e-17 62.3 9.6 1.1e-13 51.3 5.2 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 ETS78535.1 - 4.3e-11 42.0 2.9 0.63 10.3 0.0 6.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 ETS78535.1 - 5.2e-09 35.5 7.5 2.6 8.3 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat NB-ARC PF00931.22 ETS78535.1 - 2.4e-08 33.5 0.0 0.0064 15.7 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TPR_19 PF14559.6 ETS78535.1 - 1e-07 32.3 1.4 0.06 13.9 0.0 5.5 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 ETS78535.1 - 1.3e-07 31.3 7.7 0.14 12.5 0.0 6.7 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 ETS78535.1 - 2.1e-07 30.4 2.5 1.7 8.6 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 ETS78535.1 - 3.1e-07 30.4 1.7 0.17 12.6 1.2 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 ETS78535.1 - 5e-06 27.0 2.0 6.1 7.6 1.2 5.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 ETS78535.1 - 3.5e-05 24.3 5.8 12 7.0 0.2 7.6 8 1 1 9 9 9 0 Tetratricopeptide repeat NACHT PF05729.12 ETS78535.1 - 0.00033 20.6 0.0 0.0097 15.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain TPR_17 PF13431.6 ETS78535.1 - 0.0012 19.0 1.0 19 5.9 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC5 PF12862.7 ETS78535.1 - 0.051 13.7 1.6 0.27 11.3 0.0 2.9 3 1 0 3 3 2 0 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 ETS78535.1 - 1.3 9.8 4.8 50 4.8 0.1 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 ETS78535.1 - 1.6 9.1 5.5 18 5.8 0.7 4.2 3 2 0 3 3 2 0 Tetratricopeptide repeat Ank_2 PF12796.7 ETS78536.1 - 2.8e-53 178.4 0.3 3.2e-11 43.6 0.0 9.0 6 2 1 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS78536.1 - 3.6e-35 119.9 0.8 0.00018 22.0 0.0 10.7 9 2 2 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS78536.1 - 7.3e-34 112.0 0.7 0.011 16.2 0.0 15.9 17 0 0 17 17 17 7 Ankyrin repeat Ank_5 PF13857.6 ETS78536.1 - 1.7e-21 76.0 0.0 0.002 18.4 0.0 9.5 7 3 3 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 ETS78536.1 - 1.2e-18 66.6 9.1 0.0025 18.2 0.0 10.6 11 0 0 11 11 11 4 Ankyrin repeat Clr5 PF14420.6 ETS78536.1 - 0.0029 17.8 0.2 0.0088 16.2 0.2 1.9 1 0 0 1 1 1 1 Clr5 domain Gp_dh_C PF02800.20 ETS78538.1 - 5.1e-54 182.1 0.3 7.6e-54 181.6 0.3 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 ETS78538.1 - 1.3e-30 105.7 0.1 4.8e-30 103.9 0.1 2.0 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 ETS78538.1 - 0.016 15.3 0.4 0.28 11.3 0.1 2.9 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 ETS78538.1 - 0.05 13.0 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sugar_tr PF00083.24 ETS78539.1 - 1.1e-98 331.0 28.9 1.3e-98 330.8 28.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS78539.1 - 7.5e-23 81.0 23.0 7.5e-23 81.0 23.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily LapA_dom PF06305.11 ETS78539.1 - 0.52 10.2 5.1 6 6.8 0.3 3.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Trp_oprn_chp PF09534.10 ETS78539.1 - 1.6 8.5 8.0 0.79 9.5 0.1 2.7 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Fungal_trans PF04082.18 ETS78540.1 - 1.3e-23 83.3 0.0 2.2e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 ETS78541.1 - 1e-29 103.6 29.0 1.6e-29 103.0 29.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_39 PF01229.17 ETS78542.1 - 0.003 16.2 0.0 0.004 15.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Glyco_hydro_79C PF16862.5 ETS78543.1 - 4.2e-18 66.1 0.4 9.1e-18 65.1 0.4 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Aldedh PF00171.22 ETS78544.1 - 2.6e-162 540.6 0.8 2.9e-162 540.4 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.18 ETS78545.1 - 7.5e-17 61.2 0.8 1.1e-16 60.7 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS78545.1 - 2.7e-09 37.0 11.6 4.8e-09 36.2 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 ETS78546.1 - 1e-113 380.6 20.4 1.7e-113 379.9 20.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS78546.1 - 1e-29 103.6 46.1 1.4e-25 90.0 25.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS78546.1 - 0.00019 20.0 2.3 0.00019 20.0 2.3 1.9 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 ETS78546.1 - 0.0023 16.9 0.6 0.0023 16.9 0.6 2.0 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM DUF4956 PF16316.5 ETS78546.1 - 0.032 13.9 0.3 0.4 10.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4956) DLP_helical PF18709.1 ETS78546.1 - 0.24 10.6 0.1 0.36 10.0 0.1 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain adh_short_C2 PF13561.6 ETS78547.1 - 2.6e-50 171.2 0.0 3.1e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS78547.1 - 5.2e-44 150.0 0.2 6.6e-44 149.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS78547.1 - 5.3e-14 52.5 0.1 1.4e-13 51.1 0.1 1.6 1 1 0 1 1 1 1 KR domain DUF43 PF01861.16 ETS78547.1 - 0.15 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Transketolase_N PF00456.21 ETS78548.1 - 7.2e-111 370.4 0.0 9.1e-111 370.0 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ETS78548.1 - 6e-34 117.3 0.0 5.7e-33 114.1 0.0 2.1 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ETS78548.1 - 1.8e-12 47.2 0.0 4.4e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 ETS78548.1 - 3.2e-07 29.8 0.0 1.6e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 ETS78548.1 - 0.0001 22.1 0.4 0.00078 19.3 0.4 2.4 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 ETS78548.1 - 0.029 14.0 0.0 3.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Transglut_core PF01841.19 ETS78548.1 - 0.12 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily ADH_N PF08240.12 ETS78549.1 - 1.9e-24 85.7 0.9 2.6e-24 85.2 0.3 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS78549.1 - 2.6e-13 50.1 0.3 5.4e-13 49.1 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS78549.1 - 4.7e-07 29.5 0.7 0.00015 21.3 0.1 2.7 1 1 1 2 2 2 2 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 ETS78549.1 - 0.007 15.6 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 ETS78549.1 - 0.016 14.8 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.21 ETS78549.1 - 0.037 14.1 0.1 1.3 9.0 0.1 2.3 1 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ThiF PF00899.21 ETS78549.1 - 0.041 13.2 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 ThiF family FMO-like PF00743.19 ETS78550.1 - 3.2e-16 58.8 0.1 2.2e-13 49.5 0.0 2.4 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ETS78550.1 - 9.4e-14 51.4 0.0 9.5e-13 48.1 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS78550.1 - 2.1e-12 47.1 0.0 5.5e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS78550.1 - 1.1e-09 38.0 0.0 1.3e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS78550.1 - 1e-07 31.4 0.2 4.9e-05 22.6 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ETS78550.1 - 4.5e-06 26.5 0.0 0.00039 20.1 0.0 2.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ETS78550.1 - 0.0006 19.2 0.0 0.00095 18.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 ETS78550.1 - 0.00062 19.8 0.0 0.023 14.7 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 ETS78550.1 - 0.0038 16.5 0.1 0.012 14.8 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 ETS78550.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.20 ETS78550.1 - 0.15 12.1 0.0 13 5.9 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 ETS78550.1 - 0.17 11.1 0.0 2.3 7.4 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Ceramidase_alk PF04734.13 ETS78551.1 - 3e-14 52.5 0.9 1.4e-13 50.4 0.1 2.0 2 0 0 2 2 2 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal DUF2070 PF09843.9 ETS78551.1 - 0.00047 18.6 0.0 0.00071 18.0 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) Tannase PF07519.11 ETS78552.1 - 1.5e-100 337.3 2.3 2.1e-100 336.9 2.3 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Pyr_redox_2 PF07992.14 ETS78553.1 - 7.4e-37 127.2 0.2 1.2e-36 126.4 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ETS78553.1 - 1.8e-22 79.7 0.3 5.4e-22 78.1 0.1 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ETS78553.1 - 2.6e-17 63.1 1.3 6.8e-17 61.8 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS78553.1 - 0.00016 21.0 0.2 0.0014 18.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 ETS78553.1 - 0.0002 21.9 0.5 0.026 15.1 0.0 2.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 ETS78553.1 - 0.00064 19.1 0.1 0.0014 17.9 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 ETS78553.1 - 0.0023 17.8 0.4 0.18 11.7 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 ETS78553.1 - 0.0044 16.2 0.7 0.47 9.5 0.1 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 ETS78553.1 - 0.0065 15.9 0.3 0.023 14.1 0.0 2.1 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 ETS78553.1 - 0.012 15.9 0.7 1.7 8.9 0.1 2.8 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS78553.1 - 0.023 13.8 1.8 0.73 8.8 0.1 2.6 2 0 0 2 2 2 0 FAD binding domain Abhydrolase_6 PF12697.7 ETS78554.1 - 2.6e-12 47.8 2.3 3.3e-12 47.5 2.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS78554.1 - 7e-11 41.8 0.0 1.7e-10 40.6 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 ETS78554.1 - 2.1e-08 33.2 0.1 0.00043 19.1 0.2 3.1 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 ETS78554.1 - 5.2e-07 29.5 0.1 1.5e-06 28.0 0.1 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 ETS78554.1 - 0.0037 16.9 1.1 0.024 14.3 1.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS78554.1 - 0.035 13.6 0.0 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF1100 PF06500.11 ETS78554.1 - 0.14 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Transp_cyt_pur PF02133.15 ETS78555.1 - 6.6e-101 338.2 43.9 9.4e-101 337.7 43.9 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Adenine_deam_C PF13382.6 ETS78556.1 - 6.9e-44 149.2 0.2 1.2e-43 148.4 0.2 1.3 1 0 0 1 1 1 1 Adenine deaminase C-terminal domain Amidohydro_1 PF01979.20 ETS78556.1 - 3.9e-19 69.2 0.2 2.4e-17 63.3 0.2 2.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS78556.1 - 6.4e-14 52.3 0.0 8.9e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family UQ_con PF00179.26 ETS78558.1 - 7.8e-14 51.5 0.0 1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme V-ATPase_C PF03223.15 ETS78558.1 - 0.16 11.3 0.0 0.19 11.1 0.0 1.0 1 0 0 1 1 1 0 V-ATPase subunit C DUF572 PF04502.13 ETS78560.1 - 4.9e-71 240.0 0.1 5.5e-71 239.9 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) PIN_12 PF16289.5 ETS78560.1 - 0.24 11.9 2.4 0.38 11.2 2.4 1.3 1 0 0 1 1 1 0 PIN domain Acyl_transf_3 PF01757.22 ETS78561.1 - 1.8e-26 93.1 27.1 2.4e-26 92.6 27.1 1.2 1 0 0 1 1 1 1 Acyltransferase family Pox_A14 PF05767.12 ETS78561.1 - 0.47 10.6 2.0 9.8 6.4 0.2 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Hce2 PF14856.6 ETS78562.1 - 4.9e-09 36.4 0.0 7.3e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Amidoligase_2 PF12224.8 ETS78563.1 - 5.8e-13 49.1 0.1 1.3e-11 44.7 0.0 2.5 2 1 0 2 2 2 1 Putative amidoligase enzyme FlhE PF06366.13 ETS78563.1 - 0.14 12.2 0.1 1.5 8.8 0.1 2.2 2 0 0 2 2 2 0 Flagellar protein FlhE FAD_binding_4 PF01565.23 ETS78564.1 - 2.3e-32 111.6 3.3 4.4e-32 110.7 3.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS78564.1 - 7.9e-09 35.5 1.1 1.5e-08 34.6 1.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 ETS78565.1 - 2.8e-60 204.4 0.0 3.5e-60 204.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 ETS78567.1 - 1.2e-41 139.9 17.1 9.4e-07 29.4 0.3 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.33 ETS78567.1 - 7.1e-11 41.7 2.9 2e-10 40.2 0.0 2.9 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 ETS78567.1 - 1.2e-09 37.9 0.6 2.5e-09 36.9 0.1 1.9 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 ETS78567.1 - 4.2e-09 36.6 0.1 0.44 10.9 0.0 5.4 2 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ETS78567.1 - 0.00037 19.3 5.0 7.3 5.1 0.2 5.0 3 1 1 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.6 ETS78567.1 - 0.0012 18.5 1.9 3.1 7.3 0.0 3.2 2 1 1 3 3 3 3 PQQ-like domain Acetyltransf_3 PF13302.7 ETS78571.1 - 9e-12 45.9 0.0 1.6e-11 45.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS78571.1 - 0.0026 18.0 0.0 0.004 17.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Amidoligase_2 PF12224.8 ETS78572.1 - 1.1e-15 58.0 0.0 4.3e-12 46.2 0.0 2.3 2 1 0 2 2 2 2 Putative amidoligase enzyme DEAD PF00270.29 ETS78574.1 - 1.2e-19 70.8 0.0 8.1e-19 68.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS78574.1 - 9.3e-18 64.6 0.0 3.2e-16 59.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 ETS78574.1 - 0.0021 18.7 0.4 0.0057 17.4 0.4 1.7 1 0 0 1 1 1 1 RecQ zinc-binding Phosphoprotein PF00922.17 ETS78574.1 - 0.093 12.3 0.0 0.4 10.2 0.0 2.0 2 0 0 2 2 2 0 Vesiculovirus phosphoprotein Phage_integrase PF00589.22 ETS78574.1 - 0.11 12.3 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Phage integrase family AltA1 PF16541.5 ETS78575.1 - 6.2e-05 23.8 0.7 8.7e-05 23.4 0.7 1.3 1 0 0 1 1 1 1 Alternaria alternata allergen 1 PTR2 PF00854.21 ETS78576.1 - 2.5e-42 145.1 4.5 3.5e-42 144.6 4.5 1.2 1 0 0 1 1 1 1 POT family PITH PF06201.13 ETS78581.1 - 0.0089 16.3 0.0 8.9 6.5 0.0 2.7 1 1 0 3 3 3 2 PITH domain Antimicrobial21 PF14861.6 ETS78581.1 - 0.081 12.7 6.2 20 5.0 0.1 4.1 4 0 0 4 4 4 0 Plant antimicrobial peptide F-box PF00646.33 ETS78582.1 - 0.013 15.4 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 ETS78582.1 - 0.049 13.5 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 F-box-like GPI-anchored PF10342.9 ETS78583.1 - 1.4e-18 67.4 0.1 1.4e-18 67.4 0.1 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_hydro_59 PF02057.15 ETS78583.1 - 0.0059 15.9 0.0 0.0092 15.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 SOG2 PF10428.9 ETS78583.1 - 0.4 9.8 12.8 0.45 9.6 12.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIA PF03153.13 ETS78583.1 - 4.2 7.3 10.6 5 7.0 10.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tyrosinase PF00264.20 ETS78584.1 - 1.5e-53 182.4 1.4 2.3e-53 181.8 1.4 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 ETS78584.1 - 3.6e-37 127.8 0.0 6e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain Pkinase PF00069.25 ETS78585.1 - 9.9e-34 116.9 0.0 4.9e-26 91.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS78585.1 - 1e-19 70.8 0.0 2.9e-19 69.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase HOOK PF05622.12 ETS78585.1 - 2.2 6.3 6.7 0.29 9.2 1.7 1.9 3 0 0 3 3 3 0 HOOK protein bZIP_1 PF00170.21 ETS78586.1 - 1.7e-06 28.0 3.3 3.4e-06 27.0 3.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 ETS78586.1 - 0.35 11.4 7.6 0.14 12.6 2.2 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor Nnf1 PF03980.14 ETS78586.1 - 6.2 7.2 14.3 2.8 8.3 1.2 3.1 3 0 0 3 3 3 0 Nnf1 Band_7 PF01145.25 ETS78587.1 - 1.8e-31 109.5 0.7 3.2e-31 108.7 0.7 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 ETS78587.1 - 7.9e-23 80.3 0.1 2.1e-22 78.9 0.1 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 ETS78587.1 - 0.015 14.6 0.3 0.024 14.0 0.3 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein DCB PF16213.5 ETS78588.1 - 1.3e-45 155.3 10.2 2.8e-45 154.2 3.5 3.0 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 ETS78588.1 - 1.3e-39 135.6 0.0 1.3e-39 135.6 0.0 3.5 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 ETS78588.1 - 9.6e-28 96.8 10.4 8e-24 83.8 3.5 3.9 2 1 0 4 4 4 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 ETS78588.1 - 5.2e-06 26.2 0.0 0.0062 16.4 0.0 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) 3HBOH PF10605.9 ETS78588.1 - 0.0063 14.8 0.4 0.01 14.1 0.4 1.2 1 0 0 1 1 1 1 3HB-oligomer hydrolase (3HBOH) HSDR_N PF04313.14 ETS78588.1 - 0.069 13.1 0.1 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) UQ_con PF00179.26 ETS78589.1 - 6.6e-15 55.0 0.1 8.1e-15 54.7 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ETS78589.1 - 0.13 12.5 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 RWD domain Complex1_LYR PF05347.15 ETS78590.1 - 5.1e-08 32.9 0.0 1.3e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) p450 PF00067.22 ETS78591.1 - 2.3e-62 211.3 0.0 2.8e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hce2 PF14856.6 ETS78592.1 - 2.5e-16 59.8 2.9 4e-16 59.2 2.9 1.3 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor K_oxygenase PF13434.6 ETS78593.1 - 2.3e-110 368.9 0.0 2.8e-110 368.7 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ETS78593.1 - 2.5e-07 30.2 0.0 7.5e-06 25.4 0.0 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS78593.1 - 4.9e-05 23.4 0.0 0.00038 20.5 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ETS78593.1 - 0.00027 20.3 0.1 0.0016 17.8 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ETS78593.1 - 0.017 13.5 0.0 0.076 11.4 0.0 1.8 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like AMP-binding PF00501.28 ETS78594.1 - 9.2e-227 752.6 0.0 4e-81 272.8 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 ETS78594.1 - 1.4e-164 548.2 3.2 5.9e-33 114.2 0.1 6.5 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.25 ETS78594.1 - 2.4e-54 181.5 14.5 7.5e-10 39.0 0.0 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ETS78594.1 - 2.5e-14 54.0 0.2 0.00053 20.9 0.0 4.0 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 ETS78594.1 - 9e-06 25.6 3.2 0.4 10.4 0.7 4.8 5 1 0 5 5 5 3 Wax ester synthase-like Acyl-CoA acyltransferase domain Transferase PF02458.15 ETS78594.1 - 0.00072 18.3 0.4 6.7 5.2 0.0 4.6 6 0 0 6 6 6 2 Transferase family Peptidase_C14 PF00656.22 ETS78595.1 - 1.3e-61 208.7 0.0 1.7e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain MFS_1 PF07690.16 ETS78596.1 - 1.1e-23 83.8 38.8 1.1e-23 83.8 38.8 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TauD PF02668.16 ETS78597.1 - 4e-51 174.4 0.1 4.8e-51 174.1 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DHDPS PF00701.22 ETS78598.1 - 8.6e-39 133.0 0.0 2.8e-38 131.3 0.0 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans PF04082.18 ETS78599.1 - 1.1e-28 100.0 0.0 2e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS78599.1 - 1.4e-08 34.7 9.3 2.5e-08 33.9 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.11 ETS78599.1 - 4.3 7.8 8.7 10 6.6 8.7 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TauD PF02668.16 ETS78600.1 - 1.5e-50 172.5 0.2 1.8e-50 172.2 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 ETS78601.1 - 5.7e-35 120.9 33.7 5.7e-35 120.9 33.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 ETS78602.1 - 1.3e-38 132.9 30.4 1.8e-35 122.5 23.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS78602.1 - 5.5e-10 38.7 0.6 5.5e-10 38.7 0.6 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_5 PF05631.14 ETS78602.1 - 0.00045 19.3 1.5 0.00045 19.3 1.5 1.7 1 1 0 1 1 1 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 ETS78602.1 - 0.0012 17.3 2.0 0.0019 16.7 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SEN1_N PF12726.7 ETS78603.1 - 7.6e-179 596.5 1.0 9.5e-179 596.1 1.0 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 ETS78603.1 - 8.2e-72 242.1 3.5 8.2e-72 242.1 3.5 2.6 2 1 0 2 2 1 1 AAA domain AAA_12 PF13087.6 ETS78603.1 - 2.4e-60 203.6 0.0 4.3e-60 202.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ETS78603.1 - 4e-10 39.7 1.6 3.2e-06 27.0 0.5 2.9 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 ETS78603.1 - 6.1e-09 36.4 1.3 1.1e-08 35.5 0.3 2.1 2 0 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 ETS78603.1 - 4.1e-06 26.7 0.3 0.0055 16.5 0.1 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 ETS78603.1 - 6.8e-05 22.5 9.5 0.0016 18.0 2.5 3.4 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain RuvB_N PF05496.12 ETS78603.1 - 0.01 15.6 0.1 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 ETS78603.1 - 0.041 13.9 0.6 0.21 11.6 0.6 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ATP-cone PF03477.16 ETS78603.1 - 0.063 13.9 0.0 2.6 8.7 0.0 3.3 3 0 0 3 3 3 0 ATP cone domain PhoH PF02562.16 ETS78603.1 - 0.11 11.9 0.2 0.86 9.0 0.4 2.3 2 0 0 2 2 2 0 PhoH-like protein Adeno_IVa2 PF02456.15 ETS78603.1 - 0.18 10.6 0.2 0.52 9.1 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF1818 PF08848.11 ETS78603.1 - 0.2 11.8 1.2 1 9.5 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1818) TrbI_Ftype PF09677.10 ETS78603.1 - 0.4 11.0 1.5 8.6 6.7 0.0 3.0 3 0 0 3 3 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) HhH-GPD PF00730.25 ETS78604.1 - 2.1e-07 31.3 0.0 4.3e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4683 PF15735.5 ETS78604.1 - 0.00054 19.7 3.8 0.00054 19.7 3.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4683) Zn_clus PF00172.18 ETS78605.1 - 1.1e-08 35.1 13.0 1.7e-08 34.4 13.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2796 PF10986.8 ETS78605.1 - 7.9 6.4 8.5 0.26 11.3 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) 4HBT_3 PF13622.6 ETS78606.1 - 1.3e-79 268.0 1.6 1.6e-79 267.6 1.6 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 ETS78606.1 - 2e-24 85.9 0.0 2.7e-09 37.0 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase GATase_6 PF13522.6 ETS78607.1 - 1.3e-14 54.6 0.0 2.4e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ETS78607.1 - 2.3e-12 46.9 0.0 4.3e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 ETS78607.1 - 1.2e-07 31.4 0.0 2.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 ETS78607.1 - 2.1e-06 26.8 0.0 3.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Pirin PF02678.16 ETS78608.1 - 2.8e-26 91.6 0.6 6.8e-26 90.4 0.6 1.6 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 ETS78608.1 - 8.2e-05 22.2 5.5 0.00077 19.1 1.1 2.9 2 1 0 2 2 2 2 Cupin domain Sugar_tr PF00083.24 ETS78610.1 - 7.6e-81 272.3 14.3 9.1e-81 272.0 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS78610.1 - 7.4e-27 94.2 30.6 1.3e-21 76.9 22.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PIG-P PF08510.12 ETS78610.1 - 5 7.1 8.3 0.17 11.8 0.2 2.6 3 0 0 3 3 3 0 PIG-P TAL_FSA PF00923.19 ETS78611.1 - 5.6e-27 94.8 0.0 6.7e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Aldo_ket_red PF00248.21 ETS78612.1 - 1.3e-46 159.1 0.0 7.8e-46 156.6 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family RNase_H_2 PF13482.6 ETS78612.1 - 0.14 12.1 0.0 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 RNase_H superfamily Fungal_trans PF04082.18 ETS78613.1 - 9e-10 38.0 0.3 1.6e-09 37.2 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS78613.1 - 4.6e-06 26.7 1.7 8.9e-06 25.7 1.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.6 ETS78613.1 - 0.045 12.6 0.2 0.063 12.1 0.2 1.1 1 0 0 1 1 1 0 Amino acid permease Trypan_PARP PF05887.11 ETS78613.1 - 0.071 13.1 13.5 0.15 12.0 13.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 ETS78613.1 - 1.2 8.3 3.4 2 7.6 3.4 1.4 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 adh_short PF00106.25 ETS78614.1 - 3.2e-41 141.0 0.1 4.2e-41 140.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS78614.1 - 2.5e-37 128.7 0.3 7.8e-33 114.0 0.0 2.1 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS78614.1 - 1.4e-10 41.4 0.0 2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ETS78614.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 ETS78614.1 - 0.015 14.7 0.2 0.21 11.0 0.2 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 ETS78615.1 - 5.1e-45 153.8 0.1 6.6e-45 153.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS78615.1 - 1.6e-34 119.1 0.2 1.8e-34 118.9 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS78615.1 - 1.1e-14 54.7 0.2 1.5e-14 54.4 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS78615.1 - 8.9e-08 31.9 0.0 1.7e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS78615.1 - 0.00022 20.8 0.0 0.00053 19.5 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ETS78615.1 - 0.00034 19.7 0.1 0.00096 18.2 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ETS78615.1 - 0.016 14.4 0.0 0.63 9.1 0.0 2.5 2 1 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.17 ETS78615.1 - 0.041 13.0 0.0 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ETS78615.1 - 0.11 11.6 0.0 0.25 10.4 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein AAA_33 PF13671.6 ETS78616.1 - 0.00012 22.3 2.2 0.0033 17.6 2.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETS78616.1 - 0.00021 21.8 0.0 0.00093 19.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS78616.1 - 0.0006 20.2 0.4 0.001 19.5 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 ETS78616.1 - 0.0052 16.0 0.0 0.0076 15.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.6 ETS78616.1 - 0.0081 16.6 0.0 0.79 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 ETS78616.1 - 0.0086 15.1 0.1 0.013 14.5 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 ETS78616.1 - 0.017 15.4 0.4 0.043 14.1 0.2 2.0 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 ETS78616.1 - 0.024 14.4 0.1 0.083 12.6 0.1 2.0 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.6 ETS78616.1 - 0.028 14.8 0.0 0.086 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 ETS78616.1 - 0.035 13.3 0.0 0.046 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 ETS78616.1 - 0.041 13.6 0.0 0.079 12.7 0.0 1.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 ETS78616.1 - 0.069 12.9 0.1 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ETS78616.1 - 0.089 13.2 0.0 0.18 12.2 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ETS78616.1 - 0.098 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 ETS78616.1 - 0.11 11.7 0.1 0.25 10.6 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 ETS78616.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 ETS78616.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase PF06745.13 ETS78616.1 - 0.23 10.8 0.2 0.4 10.0 0.2 1.3 1 0 0 1 1 1 0 KaiC PhyH PF05721.13 ETS78617.1 - 1.4e-09 38.5 0.0 2.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 ETS78617.1 - 0.00018 20.4 0.0 0.39 9.4 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) DUF5498 PF17602.2 ETS78617.1 - 0.12 12.9 0.0 5.9 7.4 0.0 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5498) ADH_zinc_N PF00107.26 ETS78618.1 - 6.8e-22 77.8 0.1 1e-21 77.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS78618.1 - 1.1e-21 76.7 0.5 1.7e-21 76.2 0.1 1.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 ETS78618.1 - 4.3e-09 36.2 0.0 7.1e-08 32.2 0.0 2.2 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 ETS78618.1 - 7.8e-06 25.3 0.4 1.2e-05 24.8 0.4 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 ETS78618.1 - 0.0026 18.8 0.0 0.0085 17.1 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 ETS78618.1 - 0.0088 16.7 0.0 0.089 13.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 ETS78618.1 - 0.016 14.8 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 ETS78618.1 - 0.035 13.5 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Met_10 PF02475.16 ETS78618.1 - 0.056 13.2 0.1 0.087 12.6 0.1 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.13 ETS78618.1 - 0.06 12.7 0.1 0.086 12.2 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) adh_short_C2 PF13561.6 ETS78619.1 - 4e-44 150.9 2.7 5e-44 150.6 2.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS78619.1 - 3.8e-43 147.2 1.8 5.6e-43 146.7 1.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS78619.1 - 1.1e-12 48.3 1.3 2e-12 47.4 1.3 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS78619.1 - 0.069 12.3 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sugar_tr PF00083.24 ETS78620.1 - 5.4e-66 223.3 18.6 6.2e-66 223.1 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS78620.1 - 3.3e-24 85.5 43.2 6.9e-19 68.0 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.13 ETS78620.1 - 0.087 13.5 0.0 0.38 11.4 0.0 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DeoC PF01791.9 ETS78621.1 - 1.5e-10 41.1 0.2 1.9e-10 40.8 0.2 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase MFS_1 PF07690.16 ETS78622.1 - 9.4e-44 149.8 56.3 4.3e-42 144.3 53.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS78622.1 - 7.7e-16 57.6 20.4 7.7e-16 57.6 20.4 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS78622.1 - 9.2e-13 47.8 17.5 9.2e-13 47.8 17.5 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 ETS78622.1 - 0.0086 14.4 1.1 0.0086 14.4 1.1 2.5 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MACPF PF01823.19 ETS78623.1 - 0.0067 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 MAC/Perforin domain DUF16 PF01519.16 ETS78624.1 - 0.038 14.5 2.1 0.91 10.0 2.1 2.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 Rootletin PF15035.6 ETS78624.1 - 0.2 11.6 2.7 0.72 9.9 1.8 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion SKA2 PF16740.5 ETS78624.1 - 2.6 7.9 5.2 5.4 6.8 0.1 3.1 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 HET PF06985.11 ETS78625.1 - 1.5e-33 116.2 1.0 1.3e-32 113.1 0.0 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Sigma70_ner PF04546.13 ETS78625.1 - 0.00035 20.5 8.3 0.00056 19.8 8.3 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region DUF2052 PF09747.9 ETS78625.1 - 0.012 15.8 13.7 0.02 15.0 13.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Nop14 PF04147.12 ETS78625.1 - 0.015 13.6 13.2 0.02 13.2 13.2 1.1 1 0 0 1 1 1 0 Nop14-like family Tim54 PF11711.8 ETS78625.1 - 0.026 13.3 7.0 0.039 12.7 7.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_pol_3_Rpc31 PF11705.8 ETS78625.1 - 0.045 14.0 18.5 0.068 13.4 18.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CPSF100_C PF13299.6 ETS78625.1 - 0.051 13.8 2.5 0.081 13.1 2.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SDA1 PF05285.12 ETS78625.1 - 0.073 12.5 15.3 0.11 11.9 15.3 1.2 1 0 0 1 1 1 0 SDA1 Tfb4 PF03850.14 ETS78625.1 - 0.085 12.3 0.4 0.24 10.9 0.0 1.9 2 0 0 2 2 1 0 Transcription factor Tfb4 DUF2457 PF10446.9 ETS78625.1 - 0.1 11.7 17.6 0.15 11.2 17.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 ETS78625.1 - 0.14 10.2 22.4 0.2 9.7 22.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi PI3K_1B_p101 PF10486.9 ETS78625.1 - 0.16 9.8 4.2 0.21 9.3 4.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BUD22 PF09073.10 ETS78625.1 - 0.18 11.1 11.8 0.26 10.6 11.8 1.1 1 0 0 1 1 1 0 BUD22 RR_TM4-6 PF06459.12 ETS78625.1 - 0.19 11.5 7.2 0.29 10.9 7.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Prothymosin PF03247.14 ETS78625.1 - 0.22 12.0 31.3 0.39 11.2 31.3 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family FAM176 PF14851.6 ETS78625.1 - 0.24 11.1 10.2 0.5 10.0 10.2 1.5 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 ETS78625.1 - 0.38 9.0 11.6 0.69 8.1 11.6 1.3 1 0 0 1 1 1 0 CDC45-like protein RPA43_OB PF17875.1 ETS78625.1 - 0.39 11.3 4.0 0.69 10.5 4.0 1.4 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I FYDLN_acid PF09538.10 ETS78625.1 - 0.39 11.4 10.6 0.77 10.5 10.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Pox_Ag35 PF03286.14 ETS78625.1 - 0.52 10.1 10.6 0.9 9.3 10.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF913 PF06025.12 ETS78625.1 - 0.62 9.0 1.6 0.94 8.4 1.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) D123 PF07065.14 ETS78625.1 - 1.2 8.3 5.1 1.8 7.6 5.1 1.2 1 0 0 1 1 1 0 D123 DUF4820 PF16091.5 ETS78625.1 - 1.2 8.5 4.0 1.8 7.9 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4746 PF15928.5 ETS78625.1 - 1.3 8.4 16.4 2.1 7.7 16.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RAB3GAP2_C PF14656.6 ETS78625.1 - 1.6 6.8 4.5 2.4 6.3 4.5 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Presenilin PF01080.17 ETS78625.1 - 2.4 6.9 3.1 3.3 6.4 3.1 1.1 1 0 0 1 1 1 0 Presenilin RPN2_C PF18004.1 ETS78625.1 - 2.4 8.1 11.0 4 7.3 11.0 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RXT2_N PF08595.11 ETS78625.1 - 2.7 8.0 10.2 4.1 7.4 9.5 1.5 2 0 0 2 2 1 0 RXT2-like, N-terminal V_ATPase_I PF01496.19 ETS78625.1 - 3.6 5.4 7.5 42 1.9 0.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DDRGK PF09756.9 ETS78625.1 - 3.9 7.0 20.3 6.3 6.3 20.3 1.2 1 0 0 1 1 1 0 DDRGK domain ORC_WH_C PF18137.1 ETS78625.1 - 4.3 7.4 8.5 8.2 6.5 8.5 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal RRN3 PF05327.11 ETS78625.1 - 4.3 5.8 8.1 6.4 5.2 8.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Vfa1 PF08432.10 ETS78625.1 - 4.7 7.5 10.4 3.2 8.1 8.5 1.5 2 0 0 2 2 1 0 AAA-ATPase Vps4-associated protein 1 NOA36 PF06524.12 ETS78625.1 - 5.3 6.3 18.7 9.6 5.4 18.7 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 ETS78625.1 - 6.1 7.3 18.4 15 6.0 18.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TRAP_alpha PF03896.16 ETS78625.1 - 6.2 5.9 11.3 9.7 5.3 11.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PapD_N PF00345.20 ETS78628.1 - 0.08 12.9 0.3 0.1 12.5 0.3 1.1 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain SnoaL_2 PF12680.7 ETS78629.1 - 6e-08 33.3 0.0 7.5e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain N_formyltrans_C PF18216.1 ETS78629.1 - 0.036 13.7 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 N-formyltransferase dimerization C-terminal domain TPR_12 PF13424.6 ETS78630.1 - 5e-08 33.1 12.3 0.00016 21.9 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 ETS78630.1 - 1.7e-05 24.5 7.8 0.18 11.7 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 ETS78630.1 - 0.039 14.6 3.1 7.7 7.4 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ETS78630.1 - 0.043 13.9 9.2 4.7 7.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 ETS78630.1 - 0.34 11.9 13.0 13 6.9 0.1 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 ETS78630.1 - 3.3 8.1 7.3 1 9.7 0.1 3.2 2 1 2 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 ETS78632.1 - 1.3e-30 106.6 0.0 3.8e-23 82.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS78632.1 - 9.5e-22 77.5 0.0 3.4e-18 65.9 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Choline_kinase PF01633.20 ETS78632.1 - 0.0034 17.0 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 ETS78632.1 - 0.0092 15.9 2.1 0.029 14.3 0.1 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family FAD_binding_4 PF01565.23 ETS78633.1 - 3.2e-31 107.9 0.5 5.9e-31 107.1 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS78633.1 - 9.5e-19 67.2 2.7 1.1e-18 67.1 0.9 2.1 2 0 0 2 2 2 1 Berberine and berberine like BMF PF15185.6 ETS78633.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis ZU5 PF00791.20 ETS78633.1 - 0.17 12.2 0.0 5.6 7.4 0.0 2.5 2 0 0 2 2 2 0 ZU5 domain UNC45-central PF11701.8 ETS78634.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central FAD_binding_4 PF01565.23 ETS78635.1 - 4.2e-24 84.9 0.4 7.1e-24 84.1 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS78635.1 - 8.7e-05 22.5 0.0 0.00022 21.3 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Helo_like_N PF17111.5 ETS78636.1 - 5.3e-18 65.2 0.9 7e-18 64.8 0.9 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins FeoC PF09012.10 ETS78636.1 - 0.13 12.4 0.1 0.46 10.6 0.1 1.9 2 0 0 2 2 2 0 FeoC like transcriptional regulator TPR_10 PF13374.6 ETS78637.1 - 1.6e-29 100.9 6.7 1.3e-11 44.0 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 ETS78637.1 - 9.7e-28 96.3 2.6 9.9e-13 48.2 0.0 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 ETS78637.1 - 1.3e-10 40.5 1.3 0.024 14.7 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat NB-ARC PF00931.22 ETS78637.1 - 1.5e-05 24.3 0.0 0.052 12.7 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain TPR_1 PF00515.28 ETS78637.1 - 0.00014 21.5 0.0 3.3 7.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ETS78637.1 - 0.00038 20.4 1.2 5.2 7.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS78637.1 - 0.0012 18.3 0.2 0.0023 17.4 0.2 1.4 1 0 0 1 1 1 1 MalT-like TPR region AAA_16 PF13191.6 ETS78637.1 - 0.0027 18.1 0.2 0.036 14.4 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain TPR_16 PF13432.6 ETS78637.1 - 0.0091 16.6 0.4 0.21 12.2 0.2 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 ETS78637.1 - 0.0094 16.3 2.1 4.2 8.0 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ETS78637.1 - 0.021 15.3 0.1 1.1 9.8 0.0 3.2 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 ETS78637.1 - 0.043 14.5 1.3 7.3 7.5 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat AAA_22 PF13401.6 ETS78637.1 - 0.14 12.5 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_8 PF13181.6 ETS78637.1 - 0.14 12.4 1.4 48 4.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Nop14 PF04147.12 ETS78637.1 - 3 5.9 8.1 4.1 5.5 8.1 1.1 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 ETS78637.1 - 6.1 5.9 9.0 9.1 5.3 9.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Tetraspanin PF00335.20 ETS78638.1 - 4e-05 23.4 0.4 6.8e-05 22.7 0.4 1.4 1 1 0 1 1 1 1 Tetraspanin family Zn_clus PF00172.18 ETS78639.1 - 2.4e-05 24.4 11.5 4.2e-05 23.6 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPX PF03105.19 ETS78639.1 - 0.00013 22.1 12.7 0.00018 21.6 12.7 1.1 1 0 0 1 1 1 1 SPX domain Sin_N PF04801.13 ETS78639.1 - 0.2 10.8 27.2 0.32 10.1 27.2 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region CCSAP PF15748.5 ETS78639.1 - 0.33 11.1 20.3 0.48 10.5 20.3 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Ndc1_Nup PF09531.10 ETS78639.1 - 0.41 9.3 10.1 0.5 9.0 10.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TPR_14 PF13428.6 ETS78639.1 - 0.57 11.2 8.0 1.9 9.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF913 PF06025.12 ETS78639.1 - 1.1 8.2 6.6 1.5 7.7 6.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Band_3_cyto PF07565.13 ETS78639.1 - 2.5 7.8 15.6 4 7.2 15.6 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Plasmodium_Vir PF05795.11 ETS78639.1 - 2.9 7.2 7.3 4.1 6.7 7.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Dickkopf_N PF04706.12 ETS78639.1 - 2.9 8.4 9.5 9.2 6.8 9.6 1.8 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region PAT1 PF09770.9 ETS78639.1 - 3 6.0 29.4 4.3 5.5 29.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BORG_CEP PF14957.6 ETS78639.1 - 4.7 8.4 9.5 9.1 7.5 9.5 1.6 1 0 0 1 1 1 0 Cdc42 effector Zip PF02535.22 ETS78639.1 - 5.9 6.0 6.1 7.6 5.6 6.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TFB6 PF17110.5 ETS78639.1 - 7.7 6.2 8.6 66 3.2 10.0 1.9 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH DUF1980 PF09323.10 ETS78639.1 - 9 6.2 6.1 18 5.2 6.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2470 PF10615.9 ETS78641.1 - 1.4e-19 70.5 0.0 1.9e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 ETS78641.1 - 0.11 12.8 2.1 0.19 12.1 2.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4499) Fungal_lectin PF07938.12 ETS78643.1 - 6.8e-05 22.4 0.0 0.00019 20.9 0.0 1.7 1 0 0 1 1 1 1 Fungal fucose-specific lectin DUF3446 PF11928.8 ETS78643.1 - 0.15 12.4 1.6 0.32 11.3 0.8 1.9 2 0 0 2 2 2 0 Early growth response N-terminal domain TMEM132D_C PF15706.5 ETS78643.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term FAD_binding_4 PF01565.23 ETS78645.1 - 2.9e-24 85.4 0.6 4.2e-24 84.9 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain Lactonase PF10282.9 ETS78647.1 - 0.00064 19.1 0.4 0.087 12.1 0.0 2.6 2 2 1 3 3 3 2 Lactonase, 7-bladed beta-propeller Lambda_CIII PF02061.16 ETS78648.1 - 0.02 15.0 0.0 0.059 13.4 0.0 1.8 1 0 0 1 1 1 0 Lambda Phage CIII bZIP_1 PF00170.21 ETS78648.1 - 0.049 13.7 10.1 0.072 13.2 10.1 1.2 1 0 0 1 1 1 0 bZIP transcription factor DUF4337 PF14235.6 ETS78648.1 - 0.93 9.6 2.7 1.4 9.0 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Lipase_GDSL_2 PF13472.6 ETS78649.1 - 0.2 12.0 2.2 1.3 9.4 2.2 2.1 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_28 PF00295.17 ETS78650.1 - 4.3e-46 157.5 0.7 5.3e-46 157.2 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 HET PF06985.11 ETS78651.1 - 2.2e-23 83.2 0.0 5e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ETS78652.1 - 2.5e-34 118.7 0.1 5.8e-34 117.6 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Phage_C PF12025.8 ETS78653.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Phage protein C ADH_zinc_N PF00107.26 ETS78654.1 - 5.4e-07 29.6 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS78654.1 - 3.7e-06 26.8 0.1 1.7e-05 24.7 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.8 ETS78654.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Abhydrolase_6 PF12697.7 ETS78655.1 - 1.5e-06 29.0 0.1 2e-06 28.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family CFEM PF05730.11 ETS78656.1 - 0.032 14.3 0.6 0.069 13.3 0.6 1.6 1 0 0 1 1 1 0 CFEM domain Glyco_hydro_61 PF03443.14 ETS78657.1 - 1.8e-56 191.4 0.1 2.3e-56 191.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Acetyltransf_1 PF00583.25 ETS78658.1 - 2.3e-10 40.7 0.0 3.8e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS78658.1 - 1.3e-08 35.2 0.0 2.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS78658.1 - 7.9e-08 32.3 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RTP1_C1 PF10363.9 ETS78659.1 - 1.3e-24 86.5 0.2 7.2e-24 84.1 0.1 2.4 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 ETS78659.1 - 1.8e-09 37.1 0.3 4.6e-09 35.8 0.3 1.7 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 DUF4695 PF15766.5 ETS78659.1 - 0.067 13.4 1.8 0.17 12.1 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) DUF3644 PF12358.8 ETS78659.1 - 0.13 12.8 0.0 0.54 10.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) ACBP PF00887.19 ETS78661.1 - 2.5e-24 85.3 0.0 8.2e-24 83.6 0.0 1.9 2 0 0 2 2 2 1 Acyl CoA binding protein Stevor PF17410.2 ETS78661.1 - 0.22 11.1 1.3 0.31 10.5 1.3 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Ribonuclease_3 PF00636.26 ETS78662.1 - 6.8e-14 52.4 0.0 1.8e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 ETS78662.1 - 1.4e-12 47.8 0.0 2.8e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 ETS78662.1 - 0.0097 16.6 0.0 0.023 15.4 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif GIT1_C PF12205.8 ETS78662.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term RSS_P20 PF11757.8 ETS78662.1 - 0.086 13.3 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain MRP-S33 PF08293.11 ETS78663.1 - 3.2e-27 94.6 0.1 3.8e-27 94.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PUF PF00806.19 ETS78664.1 - 8.8e-36 119.6 0.9 2.6e-06 26.8 0.0 8.7 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RasGEF PF00617.19 ETS78664.1 - 0.16 12.2 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 RasGEF domain Het-C PF07217.11 ETS78665.1 - 5.7e-280 929.7 0.0 7.1e-280 929.4 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Phage_holin_2_4 PF16082.5 ETS78665.1 - 0.17 11.6 0.8 0.64 9.8 0.8 2.0 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like PP2C PF00481.21 ETS78666.1 - 3.5e-43 148.1 0.0 6.5e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 ETS78666.1 - 0.0007 19.6 0.0 0.36 10.7 0.0 3.0 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 ETS78666.1 - 0.0053 16.4 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C DUF5572 PF17733.1 ETS78667.1 - 5.1e-13 48.6 0.7 2e-12 46.7 0.3 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5572) DAO PF01266.24 ETS78669.1 - 2e-29 103.3 0.1 2.3e-29 103.1 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS78669.1 - 0.00027 20.3 0.0 0.001 18.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS78669.1 - 0.00035 20.8 0.1 0.0008 19.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Glu_dehyd_C PF16912.5 ETS78669.1 - 0.0085 15.6 0.2 2.7 7.4 0.0 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus FAD_binding_3 PF01494.19 ETS78669.1 - 0.011 15.0 0.2 0.033 13.4 0.1 1.8 3 0 0 3 3 3 0 FAD binding domain Pyr_redox PF00070.27 ETS78669.1 - 0.031 14.8 0.9 0.17 12.4 0.3 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS78669.1 - 0.046 12.8 0.0 0.085 11.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 ETS78669.1 - 0.066 13.7 0.0 0.13 12.7 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding HI0933_like PF03486.14 ETS78669.1 - 0.27 9.9 0.0 0.38 9.4 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Lyase_1 PF00206.20 ETS78670.1 - 6.9e-19 68.4 0.0 1.1e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 ETS78670.1 - 8.5e-17 61.5 0.0 1.8e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus adh_short PF00106.25 ETS78671.1 - 4.1e-46 156.9 0.2 7.8e-46 156.0 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS78671.1 - 2e-45 155.2 0.0 3e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS78671.1 - 2.6e-10 40.5 0.2 4.4e-10 39.8 0.2 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ETS78671.1 - 0.0082 16.0 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 ETS78671.1 - 0.022 14.2 0.0 0.057 12.9 0.0 1.9 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 ETS78671.1 - 0.027 13.8 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 ETS78671.1 - 0.03 14.0 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DFP PF04127.15 ETS78671.1 - 0.094 12.5 0.1 0.66 9.8 0.1 2.1 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PAP2 PF01569.21 ETS78672.1 - 1.9e-19 69.8 2.9 5.5e-19 68.3 2.9 1.8 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 ETS78672.1 - 0.00071 19.3 4.3 0.002 17.8 4.3 1.9 1 1 0 1 1 1 1 PAP2 superfamily Glyco_hydro_43 PF04616.14 ETS78673.1 - 1.1e-40 139.7 7.1 1.3e-40 139.6 7.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DAO PF01266.24 ETS78674.1 - 2.6e-50 172.0 0.1 3e-50 171.8 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS78674.1 - 1.3e-06 28.5 0.0 1.4e-05 25.1 0.0 2.2 1 1 1 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ETS78674.1 - 6.1e-05 23.2 0.1 0.00038 20.6 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ETS78674.1 - 0.0061 15.8 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 ETS78674.1 - 0.0093 15.1 0.1 0.019 14.1 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS78674.1 - 0.021 14.0 0.0 0.08 12.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ETS78674.1 - 0.077 12.3 0.0 0.31 10.3 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 ETS78674.1 - 0.18 11.1 0.0 1.1 8.5 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FA_desaturase PF00487.24 ETS78675.1 - 0.31 10.8 3.6 0.51 10.1 3.6 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Citrate_bind PF16114.5 ETS78676.1 - 1.1e-85 285.6 0.0 1.5e-85 285.1 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 ETS78676.1 - 1.2e-07 31.5 0.0 1.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Citrate_synt PF00285.21 ETS78677.1 - 5.4e-20 71.8 0.0 6e-17 61.8 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 ETS78677.1 - 7.5e-19 68.2 0.1 2.2e-18 66.7 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 ETS78677.1 - 1.3e-14 54.3 0.2 2.5e-14 53.3 0.2 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 ETS78677.1 - 2.9e-06 27.1 0.1 0.0001 22.1 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Ribosomal_L30 PF00327.20 ETS78678.1 - 6e-17 61.3 0.0 7.6e-17 60.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MRG PF05712.13 ETS78679.1 - 4.6e-60 202.3 0.2 5.2e-60 202.2 0.2 1.0 1 0 0 1 1 1 1 MRG BST2 PF16716.5 ETS78679.1 - 0.00026 21.5 0.0 0.46 11.1 0.0 2.2 2 0 0 2 2 2 2 Bone marrow stromal antigen 2 Tudor-knot PF11717.8 ETS78682.1 - 1.8e-08 34.1 0.2 2.7e-08 33.6 0.2 1.3 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PWWP PF00855.17 ETS78682.1 - 0.022 15.2 0.1 0.029 14.8 0.1 1.2 1 0 0 1 1 1 0 PWWP domain Chromo PF00385.24 ETS78682.1 - 0.042 13.8 0.2 0.064 13.2 0.2 1.3 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Legionella_OMP PF05150.12 ETS78682.1 - 0.064 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Legionella pneumophila major outer membrane protein precursor Cnl2_NKP2 PF09447.10 ETS78683.1 - 6.1e-29 100.0 2.4 2.2e-28 98.2 1.2 2.3 2 0 0 2 2 2 1 Cnl2/NKP2 family protein Syntaxin_2 PF14523.6 ETS78683.1 - 0.0049 17.2 2.3 0.022 15.1 0.3 2.1 2 0 0 2 2 2 1 Syntaxin-like protein HAUS-augmin3 PF14932.6 ETS78683.1 - 0.046 13.3 4.8 0.027 14.0 1.9 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF2017 PF09438.10 ETS78683.1 - 0.052 13.4 2.1 0.095 12.6 2.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2017) Nnf1 PF03980.14 ETS78683.1 - 0.053 13.9 5.7 0.13 12.6 1.8 2.7 3 0 0 3 3 3 0 Nnf1 APG6_N PF17675.1 ETS78683.1 - 0.091 13.3 7.1 0.24 11.9 7.1 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region CelTOS PF18659.1 ETS78683.1 - 0.12 12.8 1.0 0.97 9.9 0.0 2.1 1 1 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites Nefa_Nip30_N PF10187.9 ETS78683.1 - 1.2 9.5 6.9 10 6.5 2.5 2.8 1 1 1 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 CENP-Q PF13094.6 ETS78685.1 - 7.4e-45 153.2 1.0 7.4e-45 153.2 1.0 4.5 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Pkinase PF00069.25 ETS78686.1 - 3.2e-16 59.5 0.0 1.5e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS78686.1 - 1.3e-08 34.5 0.0 8.4e-08 31.8 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ETS78686.1 - 0.34 10.8 0.0 0.34 10.8 0.0 3.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family MFS_1 PF07690.16 ETS78687.1 - 1.5e-09 37.2 27.2 6.8e-09 35.1 23.8 2.5 1 1 2 3 3 3 1 Major Facilitator Superfamily UNC-93 PF05978.16 ETS78687.1 - 1.5e-06 28.0 1.4 1.5e-06 28.0 1.4 1.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 ETS78687.1 - 1.9e-06 27.0 6.2 3.9e-06 26.0 6.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MR_MLE_C PF13378.6 ETS78688.1 - 2e-58 197.6 0.0 2.4e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ETS78688.1 - 6e-17 61.9 0.0 1.2e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Aldo_ket_red PF00248.21 ETS78689.1 - 1.5e-50 172.1 0.1 6.9e-50 169.9 0.1 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family DHDPS PF00701.22 ETS78690.1 - 7e-30 103.7 0.0 8.7e-30 103.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF818 PF05677.12 ETS78690.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) NAD_binding_4 PF07993.12 ETS78691.1 - 5.1e-38 130.7 0.0 1e-37 129.7 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 ETS78691.1 - 1e-35 123.1 0.0 1.6e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 ETS78691.1 - 1.6e-12 47.4 0.0 3e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 ETS78691.1 - 1.9e-10 40.9 0.0 4.1e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 ETS78691.1 - 0.00027 20.4 0.0 0.00087 18.8 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 ETS78691.1 - 0.0051 16.7 0.2 0.015 15.2 0.2 1.8 1 1 0 1 1 1 1 KR domain MFS_1 PF07690.16 ETS78692.1 - 3.3e-37 128.2 21.3 3.3e-37 128.2 21.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS78692.1 - 1.1e-10 41.0 13.1 1.8e-10 40.3 13.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.18 ETS78693.1 - 1e-25 90.3 0.3 2e-25 89.4 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS78693.1 - 1.3e-07 31.6 8.5 1.3e-07 31.6 8.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dak1 PF02733.17 ETS78694.1 - 8.1e-107 356.7 0.9 1.1e-106 356.3 0.9 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 ETS78694.1 - 3.7e-44 150.7 1.9 7e-44 149.8 1.9 1.5 1 0 0 1 1 1 1 DAK2 domain Peptidase_M61 PF05299.12 ETS78695.1 - 0.0011 19.4 2.0 0.018 15.4 2.0 2.3 1 1 0 1 1 1 1 M61 glycyl aminopeptidase PDZ_6 PF17820.1 ETS78695.1 - 0.0034 17.2 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 PDZ domain Aminotran_1_2 PF00155.21 ETS78696.1 - 9e-36 123.8 0.0 1.2e-35 123.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Meth_synt_2 PF01717.18 ETS78699.1 - 1.4e-152 507.6 0.0 6.2e-147 489.1 0.0 2.5 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 ETS78699.1 - 8.6e-120 400.0 0.4 6.2e-113 377.4 0.0 3.0 4 0 0 4 4 4 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 ETS78699.1 - 0.0036 16.5 0.0 0.2 10.8 0.0 2.4 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) CBM39 PF15886.5 ETS78699.1 - 0.029 14.3 0.1 0.063 13.2 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 32) Transp_cyt_pur PF02133.15 ETS78701.1 - 3.5e-91 306.2 31.8 4.4e-91 305.9 31.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2235 PF09994.9 ETS78703.1 - 0.024 14.0 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) MYO10_CC PF16735.5 ETS78703.1 - 0.14 12.3 2.8 0.29 11.3 0.5 2.5 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain GATase PF00117.28 ETS78704.1 - 1.6e-06 28.0 0.0 2.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I MFS_1 PF07690.16 ETS78705.1 - 5.6e-29 101.2 28.5 5.6e-29 101.2 28.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS78705.1 - 5.1e-05 22.7 7.2 5.1e-05 22.7 7.2 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB LapA_dom PF06305.11 ETS78705.1 - 6.5 6.7 5.6 3.7 7.5 0.1 3.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain TPR_12 PF13424.6 ETS78706.1 - 3.2e-39 133.1 21.7 1.9e-08 34.4 0.4 7.3 2 2 3 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.6 ETS78706.1 - 1e-34 117.4 25.4 5.6e-05 22.9 0.2 11.6 11 0 0 11 11 11 8 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS78706.1 - 3e-19 69.0 11.2 7.5e-05 22.9 0.1 8.0 2 2 3 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 ETS78706.1 - 6.4e-17 60.3 8.6 1.1 9.7 0.0 10.3 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 ETS78706.1 - 6.4e-17 60.3 20.0 0.2 11.7 0.1 11.1 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 ETS78706.1 - 3.3e-16 59.6 17.9 0.0059 17.1 0.0 9.7 3 2 8 11 11 11 6 Tetratricopeptide repeat TPR_2 PF07719.17 ETS78706.1 - 1.2e-14 53.2 17.9 0.036 14.2 0.1 10.5 11 0 0 11 11 10 4 Tetratricopeptide repeat NB-ARC PF00931.22 ETS78706.1 - 4.2e-12 45.8 0.0 9.3e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_6 PF13174.6 ETS78706.1 - 1.6e-11 44.0 5.9 0.62 10.8 0.0 9.6 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_14 PF13428.6 ETS78706.1 - 3.9e-10 39.7 23.7 4.3 8.4 0.2 11.5 10 1 1 11 11 11 1 Tetratricopeptide repeat TPR_1 PF00515.28 ETS78706.1 - 2.3e-09 36.7 8.7 0.81 9.6 0.1 9.2 10 0 0 10 10 10 2 Tetratricopeptide repeat Paf67 PF10255.9 ETS78706.1 - 2.4e-09 36.7 0.7 0.027 13.5 0.0 5.8 2 1 5 7 7 7 2 RNA polymerase I-associated factor PAF67 TPR_16 PF13432.6 ETS78706.1 - 4e-09 37.0 9.1 0.7 10.6 0.0 8.0 7 1 1 8 8 8 2 Tetratricopeptide repeat PPR PF01535.20 ETS78706.1 - 7.3e-08 32.2 2.9 36 4.9 0.0 8.9 11 0 0 11 11 8 0 PPR repeat AAA_22 PF13401.6 ETS78706.1 - 2.6e-06 27.7 0.2 1.4e-05 25.4 0.0 2.3 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 ETS78706.1 - 2.9e-05 24.0 0.0 6.5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_20 PF14561.6 ETS78706.1 - 0.0051 17.1 31.9 7.7 6.9 0.2 9.9 4 2 7 11 11 11 0 Tetratricopeptide repeat SRP54 PF00448.22 ETS78706.1 - 0.0074 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PPR_2 PF13041.6 ETS78706.1 - 0.017 15.3 5.3 1.3e+02 2.9 0.2 7.6 11 0 0 11 11 9 0 PPR repeat family PNP_UDP_1 PF01048.20 ETS78706.1 - 0.018 14.3 0.0 0.043 13.1 0.0 1.6 1 0 0 1 1 1 0 Phosphorylase superfamily DUF4248 PF14053.6 ETS78706.1 - 0.11 12.5 0.8 31 4.7 0.0 4.4 6 0 0 6 6 4 0 Domain of unknown function (DUF4248) YfdX PF10938.8 ETS78706.1 - 0.25 11.3 18.5 0.13 12.2 2.3 4.2 3 1 1 4 4 4 0 YfdX protein AAA_lid_8 PF17868.1 ETS78706.1 - 0.47 10.4 21.6 3.8 7.5 0.2 7.7 4 1 3 9 9 9 0 AAA lid domain YIEGIA PF14045.6 ETS78706.1 - 0.49 9.2 3.1 3.1 6.6 0.1 3.5 4 0 0 4 4 4 0 YIEGIA protein AAA_16 PF13191.6 ETS78706.1 - 0.7 10.3 8.0 0.77 10.1 3.5 3.5 2 1 0 2 2 2 0 AAA ATPase domain DUF1627 PF07789.12 ETS78706.1 - 1.6 8.4 5.1 23 4.6 0.2 4.2 3 1 2 5 5 5 0 Protein of unknown function (DUF1627) TPR_17 PF13431.6 ETS78706.1 - 6.4 7.4 6.6 71 4.1 0.0 4.8 6 0 0 6 6 3 0 Tetratricopeptide repeat Transp_cyt_pur PF02133.15 ETS78707.1 - 3.2e-101 339.3 43.3 3.8e-101 339.0 43.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Aminotran_1_2 PF00155.21 ETS78708.1 - 1.6e-18 67.0 0.0 2e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ETS78708.1 - 0.0066 15.3 0.0 0.0093 14.8 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DUF3426 PF11906.8 ETS78708.1 - 0.17 12.1 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) Amidase PF01425.21 ETS78709.1 - 3.8e-78 263.5 0.0 6.9e-78 262.6 0.0 1.4 1 1 0 1 1 1 1 Amidase ABC_tran_CTD PF16326.5 ETS78709.1 - 0.4 11.0 3.1 13 6.2 0.2 2.8 3 0 0 3 3 3 0 ABC transporter C-terminal domain DAO PF01266.24 ETS78710.1 - 7e-32 111.4 0.0 7.9e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS78710.1 - 0.1 11.8 0.1 1.2 8.3 0.0 2.3 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydr_30_2 PF14587.6 ETS78711.1 - 8e-19 68.5 0.2 2.2e-18 67.0 0.2 1.7 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 ETS78711.1 - 6e-12 45.6 6.1 1.6e-11 44.2 6.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 ETS78711.1 - 1.9e-11 43.8 0.1 2.8e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 CBM_1 PF00734.18 ETS78711.1 - 4.9e-10 39.2 15.3 4.9e-10 39.2 15.3 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_30 PF02055.16 ETS78711.1 - 1.2e-07 31.1 0.5 1.2e-07 31.1 0.5 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 30 TIM-barrel domain Melibiase_C PF17801.1 ETS78711.1 - 0.049 13.7 1.4 0.14 12.2 0.3 2.5 2 1 0 2 2 2 0 Alpha galactosidase C-terminal beta sandwich domain Polysacc_deac_1 PF01522.21 ETS78712.1 - 1.5e-16 60.4 0.0 3.3e-16 59.3 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 ETS78712.1 - 0.00051 19.8 0.2 0.002 17.8 0.1 2.0 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 ETS78712.1 - 0.049 12.0 0.0 0.049 12.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2194) ABC2_membrane PF01061.24 ETS78713.1 - 1.6e-88 295.6 57.1 2.7e-46 157.6 20.5 2.8 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 ETS78713.1 - 5e-35 119.3 5.6 4.8e-31 106.5 0.3 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.27 ETS78713.1 - 9.8e-35 120.1 0.0 4.7e-16 59.5 0.0 3.5 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 ETS78713.1 - 1.1e-16 61.1 0.2 3e-16 59.8 0.2 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 ETS78713.1 - 4.3e-07 29.7 0.0 0.00024 20.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ETS78713.1 - 4.8e-07 30.3 0.1 0.00011 22.6 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 ETS78713.1 - 2.8e-06 27.3 0.0 0.0011 18.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 ETS78713.1 - 0.00028 21.5 0.0 0.092 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ETS78713.1 - 0.0004 20.6 0.1 0.075 13.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ETS78713.1 - 0.0005 19.7 0.3 0.035 13.9 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ETS78713.1 - 0.00071 19.5 0.2 1.6 8.4 0.0 2.6 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETS78713.1 - 0.0014 18.1 0.0 1.5 8.2 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 ETS78713.1 - 0.0047 16.7 0.5 0.32 10.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ETS78713.1 - 0.0064 16.8 0.3 0.7 10.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 ETS78713.1 - 0.01 15.5 0.4 0.1 12.2 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 ETS78713.1 - 0.012 16.1 0.1 2.5 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF2145 PF09916.9 ETS78713.1 - 0.015 15.0 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) NACHT PF05729.12 ETS78713.1 - 0.034 14.1 0.1 2.3 8.1 0.1 2.7 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 ETS78713.1 - 0.035 14.5 0.0 8.3 6.9 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 ETS78713.1 - 0.049 14.1 0.4 0.18 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ETS78713.1 - 0.14 12.4 0.1 4.3 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ETS78713.1 - 0.2 11.7 0.0 29 4.8 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.7 ETS78713.1 - 0.75 8.8 44.7 0.014 14.6 15.9 3.0 2 1 1 3 3 3 0 ABC-2 family transporter protein DUF2304 PF10066.9 ETS78713.1 - 4.7 7.5 13.6 17 5.7 2.3 4.0 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) Zn_clus PF00172.18 ETS78714.1 - 8.7e-08 32.2 18.9 8.7e-08 32.2 18.9 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-PHD-like PF15446.6 ETS78714.1 - 0.011 15.4 8.1 0.015 14.9 8.1 1.2 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain DUF5544 PF17698.1 ETS78714.1 - 0.17 12.0 6.2 0.46 10.6 0.8 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5544) Glyco_hydro_79C PF16862.5 ETS78715.1 - 6.8e-13 49.4 0.0 1.4e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Ank_2 PF12796.7 ETS78716.1 - 4.4e-18 65.7 0.1 1e-07 32.4 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS78716.1 - 1.7e-17 61.7 0.9 0.002 18.5 0.0 6.2 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 ETS78716.1 - 1.1e-16 61.0 0.2 0.00031 21.2 0.0 6.2 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 ETS78716.1 - 8.5e-16 57.6 2.8 0.0062 16.9 0.0 6.4 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 ETS78716.1 - 8.4e-11 41.9 0.1 0.041 14.2 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeats (many copies) p450 PF00067.22 ETS78717.1 - 1e-36 126.7 0.0 1.2e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S25 PF03297.15 ETS78717.1 - 0.044 14.0 0.4 1.8 8.8 0.2 2.9 3 0 0 3 3 3 0 S25 ribosomal protein DUF1993 PF09351.10 ETS78718.1 - 1.4e-44 152.1 0.0 1.5e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) COesterase PF00135.28 ETS78719.1 - 2.7e-90 303.7 0.0 4e-90 303.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS78719.1 - 0.00018 21.5 0.2 0.0024 17.7 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS78719.1 - 0.032 13.7 0.1 0.065 12.7 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family GPI-anchored PF10342.9 ETS78720.1 - 8.7e-17 61.7 1.3 8.7e-17 61.7 1.3 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 ETS78720.1 - 0.054 13.3 3.3 0.081 12.7 3.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) RAP1 PF07218.11 ETS78720.1 - 6 5.0 13.7 6.9 4.8 13.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 ETS78720.1 - 7 5.1 7.3 7.7 4.9 7.3 1.0 1 0 0 1 1 1 0 Macoilin family Peptidase_C97 PF05903.14 ETS78721.1 - 2.4e-06 27.5 0.3 3.5e-06 26.9 0.3 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 ETS78721.1 - 0.011 16.1 4.8 0.095 13.0 4.8 2.4 1 1 0 1 1 1 0 Lecithin retinol acyltransferase GSCFA PF08885.11 ETS78721.1 - 0.058 13.0 3.3 0.12 12.0 3.3 1.6 1 1 0 1 1 1 0 GSCFA family 2OG-FeII_Oxy PF03171.20 ETS78722.1 - 2e-19 69.9 0.0 3.3e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ETS78722.1 - 1.2e-17 64.7 0.0 2e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.16 ETS78723.1 - 5.8e-26 91.2 38.1 5.8e-26 91.2 38.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS78723.1 - 1e-05 25.0 12.0 1e-05 25.0 12.0 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4448 PF14610.6 ETS78723.1 - 0.23 11.2 1.9 2.2 8.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) Ank_2 PF12796.7 ETS78724.1 - 1.4e-90 297.9 3.9 2.9e-15 56.6 0.1 8.1 2 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS78724.1 - 8e-66 210.2 2.9 4.9e-05 23.4 0.0 15.8 16 0 0 16 16 16 10 Ankyrin repeat Ank_4 PF13637.6 ETS78724.1 - 5.1e-65 215.1 1.7 2.1e-10 40.9 0.0 11.5 4 2 7 12 12 12 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS78724.1 - 3.4e-63 208.9 5.7 1.3e-08 35.0 0.1 12.3 4 3 7 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 ETS78724.1 - 2.2e-56 186.0 8.5 7.1e-05 23.1 0.0 14.4 13 1 1 14 14 14 11 Ankyrin repeat NACHT PF05729.12 ETS78724.1 - 3.1e-08 33.7 0.8 6.6e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 NACHT domain SesA PF17107.5 ETS78724.1 - 0.0014 18.8 2.3 0.0015 18.7 0.4 2.0 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 ETS78724.1 - 0.021 15.1 1.1 0.12 12.7 0.0 2.7 2 1 1 3 3 3 0 AAA domain TFA2_Winged_2 PF18121.1 ETS78724.1 - 0.073 12.8 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 AAA_16 PF13191.6 ETS78724.1 - 0.13 12.6 0.2 0.56 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Abhydrolase_3 PF07859.13 ETS78725.1 - 1e-11 45.1 0.1 1.3e-11 44.8 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS78725.1 - 5.2e-11 42.1 1.8 1.8e-10 40.3 1.8 1.7 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 ETS78725.1 - 0.034 13.0 0.0 0.049 12.5 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 ETS78725.1 - 0.13 12.9 5.5 0.15 12.6 3.5 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS78725.1 - 0.18 11.1 1.2 0.51 9.6 1.2 1.8 1 1 0 1 1 1 0 Serine aminopeptidase, S33 FMN_dh PF01070.18 ETS78726.1 - 2.6e-100 335.8 0.0 3.3e-100 335.5 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ETS78726.1 - 4.4e-24 84.4 0.0 9.4e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 ETS78726.1 - 3e-05 23.2 1.1 8.2e-05 21.8 0.4 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ETS78726.1 - 3.6e-05 23.1 0.1 5.9e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 ETS78726.1 - 0.00014 21.4 0.2 0.00023 20.6 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 ETS78726.1 - 0.042 13.0 0.1 0.069 12.4 0.1 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 ETS78726.1 - 0.15 11.5 0.0 0.35 10.3 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein Fungal_trans PF04082.18 ETS78727.1 - 3.5e-05 23.0 0.0 6.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS78727.1 - 0.00011 22.3 11.6 0.00017 21.7 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 ETS78728.1 - 1e-61 209.0 0.0 1.3e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS78728.1 - 1e-30 107.2 0.0 1.8e-30 106.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS78728.1 - 4.9e-07 29.2 0.9 0.02 14.0 0.2 2.6 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 ETS78728.1 - 2e-05 24.8 0.2 7.2e-05 22.9 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ETS78728.1 - 0.0019 17.5 0.1 0.012 14.9 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 ETS78728.1 - 0.0025 17.1 0.1 0.24 10.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS78728.1 - 0.0038 16.8 1.8 0.038 13.6 0.4 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS78728.1 - 0.0054 15.5 0.1 0.026 13.2 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 ETS78728.1 - 0.0063 15.8 0.3 1.9 7.7 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS78728.1 - 0.0077 15.3 0.1 0.014 14.5 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein CPDase PF07823.11 ETS78729.1 - 6.4e-39 133.7 0.0 7.3e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein Haem_degrading PF03928.14 ETS78730.1 - 3.9e-33 114.0 0.1 5e-33 113.7 0.1 1.1 1 0 0 1 1 1 1 Haem-degrading Baculo_PEP_C PF04513.12 ETS78731.1 - 2.9e-05 24.1 12.9 0.021 14.8 1.3 3.0 1 1 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Zincin_2 PF10103.9 ETS78731.1 - 0.14 11.4 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 Zincin-like metallopeptidase BMC PF00936.19 ETS78731.1 - 0.25 11.4 6.6 0.051 13.6 2.3 2.1 2 1 0 2 2 2 0 BMC domain FlaC_arch PF05377.11 ETS78731.1 - 1.7 9.1 4.5 2.5 8.6 0.4 3.0 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Ank_2 PF12796.7 ETS78732.1 - 2.9e-11 43.8 0.0 0.00013 22.4 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS78732.1 - 2.3e-07 31.2 0.4 0.13 12.8 0.0 4.4 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS78732.1 - 1.8e-05 24.7 0.1 1.9 9.3 0.0 4.9 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 ETS78732.1 - 0.0013 19.1 0.0 26 5.5 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 ETS78732.1 - 0.0016 18.7 0.1 1.9 8.9 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeats (many copies) COesterase PF00135.28 ETS78733.1 - 5e-64 217.0 0.0 6.3e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS78733.1 - 5e-07 29.8 1.7 1e-05 25.5 0.2 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS78733.1 - 0.21 10.4 0.0 11 4.7 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase MOSC PF03473.17 ETS78736.1 - 2.6e-29 101.9 0.0 4.1e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 ETS78736.1 - 3.1e-17 62.5 0.1 6.5e-17 61.5 0.1 1.5 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain KdpC PF02669.15 ETS78736.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Glyco_hydro_3_C PF01915.22 ETS78737.1 - 7.1e-43 146.9 0.0 1.1e-42 146.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS78737.1 - 1.4e-32 113.4 0.0 2.1e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain WSC PF01822.19 ETS78737.1 - 2.2e-17 63.0 12.7 2.2e-17 63.0 12.7 1.8 2 0 0 2 2 2 1 WSC domain Fn3-like PF14310.6 ETS78737.1 - 1.1e-09 38.2 0.0 2.2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_63 PF03200.16 ETS78738.1 - 3.8e-09 35.8 5.6 4.7e-08 32.2 1.5 3.8 3 1 0 3 3 3 1 Glycosyl hydrolase family 63 C-terminal domain CorA PF01544.18 ETS78739.1 - 1.4e-05 24.6 1.1 1.4e-05 24.6 1.1 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Cyt_bd_oxida_II PF02322.15 ETS78739.1 - 0.0057 16.1 7.2 0.011 15.1 7.2 1.5 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II Dymeclin PF09742.9 ETS78739.1 - 0.044 12.2 0.9 0.068 11.6 0.9 1.2 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein CPP1-like PF11833.8 ETS78739.1 - 0.45 10.1 4.1 0.75 9.4 1.5 2.3 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like RasGEF PF00617.19 ETS78741.1 - 5.8e-45 153.6 0.7 1.2e-44 152.7 0.7 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ETS78741.1 - 9.9e-13 48.2 0.4 6.3e-12 45.7 0.0 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.22 ETS78741.1 - 4.8e-07 29.5 0.0 2.5e-06 27.2 0.0 2.1 2 1 0 2 2 2 1 Ras family Roc PF08477.13 ETS78741.1 - 0.021 15.0 0.0 0.066 13.4 0.0 1.9 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 ETS78741.1 - 0.024 14.5 0.5 0.098 12.4 0.0 2.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 ETS78741.1 - 0.043 13.2 0.0 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 ETS78741.1 - 0.16 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ETS78741.1 - 0.17 12.1 0.1 3 8.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain SCF PF02404.15 ETS78741.1 - 0.17 11.2 1.3 6.7 6.0 0.2 2.2 2 0 0 2 2 2 0 Stem cell factor OSCP PF00213.18 ETS78742.1 - 7.5e-46 156.4 2.6 9.7e-46 156.0 2.6 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit BAF250_C PF12031.8 ETS78742.1 - 0.084 12.2 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa ABATE PF07336.11 ETS78742.1 - 1.6 9.4 7.6 40 4.9 7.6 2.2 1 1 0 1 1 1 0 Putative stress-induced transcription regulator DUF2293 PF10056.9 ETS78743.1 - 5.1e-29 100.3 0.0 1.5e-28 98.8 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Snf7 PF03357.21 ETS78744.1 - 6.5e-36 123.5 9.5 7.7e-36 123.3 9.5 1.1 1 0 0 1 1 1 1 Snf7 Tht1 PF04163.12 ETS78744.1 - 0.17 10.6 0.4 0.2 10.4 0.4 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein DUF2203 PF09969.9 ETS78744.1 - 2.8 8.7 5.8 9.1 7.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) AAA PF00004.29 ETS78745.1 - 5.7e-89 295.4 0.0 1.4e-46 158.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ETS78745.1 - 1.7e-15 56.5 0.2 6.3e-07 29.1 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 ETS78745.1 - 1.9e-12 47.9 0.0 0.0013 19.1 0.0 4.2 2 2 2 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 ETS78745.1 - 3.2e-12 46.6 0.0 1.6e-05 25.0 0.0 3.7 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ETS78745.1 - 4.8e-12 45.9 0.0 0.00013 21.8 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ETS78745.1 - 7.1e-11 42.5 0.2 0.0019 18.5 0.0 4.1 3 2 1 4 4 3 2 AAA domain AAA_33 PF13671.6 ETS78745.1 - 9.4e-10 38.8 0.0 0.002 18.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 ETS78745.1 - 9.5e-10 38.4 0.4 0.019 14.5 0.0 3.9 4 0 0 4 4 4 3 AAA domain AAA_2 PF07724.14 ETS78745.1 - 2.9e-09 37.3 0.0 0.002 18.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 ETS78745.1 - 2.2e-08 34.5 0.0 0.0027 18.1 0.0 2.6 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 ETS78745.1 - 3.5e-08 33.4 0.0 0.012 15.3 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 ETS78745.1 - 1e-07 32.3 0.0 0.006 16.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 ETS78745.1 - 2.5e-07 30.3 0.2 0.007 15.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.12 ETS78745.1 - 3.5e-07 30.3 0.1 0.028 14.3 0.0 3.3 2 2 1 3 3 3 2 NACHT domain AAA_14 PF13173.6 ETS78745.1 - 5.4e-07 29.7 0.0 0.054 13.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 ETS78745.1 - 7.6e-07 29.2 0.0 0.019 15.0 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 ETS78745.1 - 1.2e-06 29.1 0.0 0.059 13.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Cytidylate_kin2 PF13189.6 ETS78745.1 - 4.9e-06 26.8 0.0 0.061 13.5 0.0 2.7 2 0 0 2 2 2 2 Cytidylate kinase-like family Rad17 PF03215.15 ETS78745.1 - 1.8e-05 24.7 0.0 0.048 13.6 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain ABC_tran PF00005.27 ETS78745.1 - 2.2e-05 25.0 0.0 0.5 10.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter TIP49 PF06068.13 ETS78745.1 - 3.4e-05 23.2 0.0 0.17 11.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain ATPase_2 PF01637.18 ETS78745.1 - 4.2e-05 23.6 0.0 0.17 11.7 0.0 3.1 2 2 0 2 2 2 2 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 ETS78745.1 - 6.3e-05 22.3 0.0 0.1 11.9 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin AAA_24 PF13479.6 ETS78745.1 - 6.8e-05 22.7 0.1 0.14 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 ETS78745.1 - 0.00011 22.6 0.0 0.049 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AFG1_ATPase PF03969.16 ETS78745.1 - 0.00019 20.5 0.0 0.041 12.8 0.0 2.5 2 1 0 2 2 2 1 AFG1-like ATPase ATPase PF06745.13 ETS78745.1 - 0.0002 20.8 0.0 0.19 11.0 0.0 2.8 3 0 0 3 3 3 1 KaiC AAA_3 PF07726.11 ETS78745.1 - 0.00028 20.7 0.0 0.52 10.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ETS78745.1 - 0.00039 20.0 0.0 0.71 9.4 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Parvo_NS1 PF01057.17 ETS78745.1 - 0.00045 19.4 0.1 0.27 10.3 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 TniB PF05621.11 ETS78745.1 - 0.00071 19.0 0.0 0.58 9.5 0.0 3.5 2 1 1 3 3 3 1 Bacterial TniB protein PhoH PF02562.16 ETS78745.1 - 0.00071 19.1 0.1 1 8.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_17 PF13207.6 ETS78745.1 - 0.00077 19.9 0.9 2.3 8.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 ETS78745.1 - 0.00078 18.7 0.0 0.28 10.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DAP3 PF10236.9 ETS78745.1 - 0.0012 18.0 0.0 5.2 6.1 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Viral_helicase1 PF01443.18 ETS78745.1 - 0.0016 18.2 0.0 0.27 10.9 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 ETS78745.1 - 0.002 17.4 0.0 0.89 8.7 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_11 PF13086.6 ETS78745.1 - 0.0024 17.7 0.3 2.3 7.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 ETS78745.1 - 0.0035 17.1 0.0 1.8 8.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Bac_DnaA PF00308.18 ETS78745.1 - 0.0082 16.0 0.0 2.7 7.7 0.0 3.1 4 0 0 4 4 4 1 Bacterial dnaA protein AAA_30 PF13604.6 ETS78745.1 - 0.01 15.6 0.0 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ETS78745.1 - 0.018 14.9 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_23 PF13476.6 ETS78745.1 - 0.025 15.1 0.4 0.7 10.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain SKI PF01202.22 ETS78745.1 - 0.03 14.4 0.0 5.2 7.2 0.0 3.0 3 0 0 3 3 2 0 Shikimate kinase Sigma54_activ_2 PF14532.6 ETS78745.1 - 0.04 14.0 0.0 6 7.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain PduV-EutP PF10662.9 ETS78745.1 - 0.045 13.5 0.0 7.7 6.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 ETS78745.1 - 0.057 12.8 0.2 8.6 5.8 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DUF2075 PF09848.9 ETS78745.1 - 0.073 12.3 0.8 15 4.6 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Guanylate_kin PF00625.21 ETS78745.1 - 0.073 12.8 0.0 29 4.3 0.0 4.0 3 1 1 4 4 4 0 Guanylate kinase DnaB_C PF03796.15 ETS78745.1 - 0.074 12.4 0.1 9.6 5.4 0.0 2.9 2 1 1 3 3 3 0 DnaB-like helicase C terminal domain ResIII PF04851.15 ETS78745.1 - 0.12 12.4 0.0 6.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Lactonase PF10282.9 ETS78746.1 - 3.9e-08 32.9 2.2 0.00018 20.9 0.1 3.6 3 1 1 4 4 4 3 Lactonase, 7-bladed beta-propeller NHL PF01436.21 ETS78746.1 - 3.1e-05 23.8 0.2 0.62 10.2 0.0 4.6 4 0 0 4 4 4 2 NHL repeat NUDIX PF00293.28 ETS78748.1 - 5.6e-18 65.2 1.1 6.8e-18 65.0 1.1 1.1 1 0 0 1 1 1 1 NUDIX domain ATE_C PF04377.15 ETS78749.1 - 3.3e-45 154.0 0.9 3.9e-45 153.7 0.1 1.5 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 ETS78749.1 - 2.2e-18 66.4 0.7 4.4e-18 65.4 0.7 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus POM121 PF15229.6 ETS78749.1 - 0.053 13.2 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 POM121 family Acetyltransf_6 PF13480.7 ETS78749.1 - 0.068 13.3 0.1 0.068 13.3 0.1 2.6 2 1 0 3 3 3 0 Acetyltransferase (GNAT) domain adh_short PF00106.25 ETS78750.1 - 7.9e-17 61.3 1.6 2e-13 50.3 2.3 3.0 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS78750.1 - 2.8e-09 36.9 0.0 1.4e-05 24.8 0.0 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS78750.1 - 0.00015 21.7 0.4 0.00026 21.0 0.4 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 ETS78750.1 - 0.023 14.6 0.8 0.023 14.6 0.8 2.0 2 1 0 2 2 2 0 Zinc-binding dehydrogenase DUF1479 PF07350.12 ETS78750.1 - 0.053 12.3 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) RNase_PH PF01138.21 ETS78751.1 - 1.9e-12 47.8 0.1 3.2e-11 43.9 0.1 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ETS78751.1 - 0.0022 18.0 0.2 0.0048 16.9 0.2 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cytochrom_C PF00034.21 ETS78753.1 - 7e-11 43.1 0.0 9.7e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 ETS78753.1 - 3.6e-08 33.6 0.9 1.4e-07 31.7 0.9 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 ETS78753.1 - 0.00058 19.6 0.2 0.013 15.2 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.14 ETS78753.1 - 0.074 13.7 0.0 0.081 13.6 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase TMEM154 PF15102.6 ETS78754.1 - 0.0024 17.8 2.6 0.0024 17.8 2.6 3.1 2 1 1 3 3 2 1 TMEM154 protein family RIFIN PF02009.16 ETS78754.1 - 0.014 15.3 18.0 0.053 13.4 17.9 1.7 1 1 0 1 1 1 0 Rifin DUF3948 PF13134.6 ETS78754.1 - 0.045 13.5 1.0 0.1 12.3 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) EphA2_TM PF14575.6 ETS78754.1 - 0.049 14.5 0.5 0.14 13.0 0.0 2.0 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Macoilin PF09726.9 ETS78754.1 - 0.087 11.4 12.7 0.14 10.7 12.7 1.3 1 0 0 1 1 1 0 Macoilin family DUF4448 PF14610.6 ETS78754.1 - 0.19 11.5 0.7 0.38 10.5 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.15 ETS78754.1 - 0.2 11.4 2.1 0.45 10.3 2.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF3584 PF12128.8 ETS78754.1 - 0.24 8.9 16.2 0.33 8.4 16.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMPIT PF07851.13 ETS78754.1 - 0.68 9.1 2.2 0.94 8.7 2.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Stevor PF17410.2 ETS78754.1 - 0.81 9.2 5.3 1.4 8.4 5.3 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF966 PF06136.13 ETS78754.1 - 3 7.5 23.5 1 9.0 13.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) TFIIA PF03153.13 ETS78754.1 - 3.8 7.4 28.5 0.14 12.1 16.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ATP-synt_B PF00430.18 ETS78754.1 - 4.7 7.3 29.0 17 5.5 6.3 2.6 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) LSM PF01423.22 ETS78755.1 - 5.4e-14 51.6 0.0 1e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 ETS78755.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Hfq protein Acetyltransf_1 PF00583.25 ETS78756.1 - 1.8e-12 47.5 0.0 2.6e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS78756.1 - 2.5e-10 40.4 0.0 3.7e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS78756.1 - 8.6e-09 35.7 0.0 1.4e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS78756.1 - 5.4e-07 29.5 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 ETS78756.1 - 0.00031 20.8 0.0 0.00066 19.8 0.0 1.7 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Tcell_CD4_C PF12104.8 ETS78756.1 - 0.73 9.8 2.6 3.7 7.5 2.3 2.1 2 0 0 2 2 2 0 T cell CD4 receptor C terminal region Ribonuclease_T2 PF00445.18 ETS78758.1 - 0.013 15.7 0.6 0.034 14.4 0.2 1.8 1 1 1 2 2 2 0 Ribonuclease T2 family Mob1_phocein PF03637.17 ETS78759.1 - 2.7e-70 235.8 0.0 3.3e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Mito_carr PF00153.27 ETS78760.1 - 2.3e-43 146.1 7.5 9.1e-16 57.6 0.1 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Complex1_LYR PF05347.15 ETS78761.1 - 0.002 18.1 0.6 0.0045 17.0 0.6 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ETS78761.1 - 0.037 14.8 0.4 0.052 14.3 0.4 1.5 1 1 0 1 1 1 0 Complex1_LYR-like zinc_ribbon_6 PF14599.6 ETS78762.1 - 2.4e-25 88.3 1.1 2.4e-25 88.3 1.1 3.5 4 2 0 4 4 2 1 Zinc-ribbon zf-CHY PF05495.12 ETS78762.1 - 1.6e-17 63.8 18.1 1.6e-17 63.8 18.1 3.6 2 1 1 3 3 2 1 CHY zinc finger zf-RING_2 PF13639.6 ETS78762.1 - 8e-06 26.1 13.0 8e-06 26.1 13.0 5.5 2 1 2 4 4 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 ETS78762.1 - 0.00044 20.0 11.8 0.00044 20.0 11.8 5.0 6 1 1 7 7 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ETS78762.1 - 0.0018 18.2 12.9 0.0018 18.2 12.9 6.2 4 2 1 5 5 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ETS78762.1 - 0.007 16.2 12.2 0.007 16.2 12.2 6.1 2 1 2 4 4 3 1 Zinc finger, C3HC4 type (RING finger) Paf1 PF03985.13 ETS78762.1 - 0.073 12.1 3.6 0.12 11.3 3.6 1.2 1 0 0 1 1 1 0 Paf1 EcoRI_methylase PF13651.6 ETS78762.1 - 0.12 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI TFIIA PF03153.13 ETS78762.1 - 0.54 10.2 11.8 0.19 11.7 8.3 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 ETS78762.1 - 1.1 9.0 9.5 3 7.5 9.5 1.8 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Zn-C2H2_12 PF18112.1 ETS78762.1 - 1.8 9.1 5.5 35 5.0 0.2 2.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Ank_2 PF12796.7 ETS78763.1 - 1.4e-29 102.5 1.9 2.7e-10 40.7 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS78763.1 - 1.1e-27 96.0 11.7 8.4e-09 35.8 0.6 6.1 2 1 6 8 8 8 6 Ankyrin repeats (many copies) SPX PF03105.19 ETS78763.1 - 6.3e-20 72.4 17.7 1.2e-09 38.6 1.7 3.3 1 1 2 3 3 3 3 SPX domain Ank_5 PF13857.6 ETS78763.1 - 1.5e-17 63.4 11.8 0.0011 19.2 0.0 7.1 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS78763.1 - 2.2e-17 61.4 6.7 0.0032 17.8 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 ETS78763.1 - 9e-15 54.4 7.2 0.00067 20.0 0.0 7.0 7 0 0 7 7 7 3 Ankyrin repeat GDPD PF03009.17 ETS78763.1 - 9.8e-08 32.0 0.0 9.9e-07 28.7 0.0 2.5 2 2 1 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family Rsa3 PF14615.6 ETS78763.1 - 0.087 12.4 1.8 1.9 8.1 0.1 2.9 2 0 0 2 2 2 0 Ribosome-assembly protein 3 AA_permease_N PF08403.10 ETS78763.1 - 0.2 11.2 0.2 15 5.1 0.0 2.8 3 0 0 3 3 3 0 Amino acid permease N-terminal Coa1 PF08695.10 ETS78765.1 - 2.6e-41 140.1 0.0 3.2e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Ribosomal_L3 PF00297.22 ETS78766.1 - 5.2e-12 45.4 5.1 3.1e-10 39.6 2.2 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 NFACT-R_1 PF05670.13 ETS78767.1 - 3.6e-38 130.6 0.1 7.6e-38 129.5 0.1 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF2870 PF11069.8 ETS78767.1 - 0.5 10.8 8.0 0.94 9.9 7.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) Sec62 PF03839.16 ETS78767.1 - 6.6 6.2 7.7 10 5.6 7.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 PITH PF06201.13 ETS78768.1 - 6.5e-47 159.5 0.0 7.9e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 PITH domain Sad1_UNC PF07738.13 ETS78768.1 - 0.061 13.3 0.0 0.096 12.7 0.0 1.2 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Rrn6 PF10214.9 ETS78769.1 - 6.2e-107 359.2 0.3 7.9e-107 358.8 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.12 ETS78770.1 - 3.9e-26 91.1 0.1 1e-25 89.7 0.1 1.8 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 ETS78770.1 - 0.0016 17.4 9.6 0.0027 16.7 9.6 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein ApoO PF09769.9 ETS78770.1 - 0.37 10.7 2.3 5.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Apolipoprotein O V_ATPase_I PF01496.19 ETS78770.1 - 0.59 8.0 7.5 0.72 7.7 7.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 ETS78770.1 - 0.6 9.1 13.8 0.5 9.4 12.4 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ERM PF00769.19 ETS78770.1 - 0.67 9.7 23.1 1.1 9.0 23.1 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LMBR1 PF04791.16 ETS78770.1 - 0.8 8.5 2.9 0.84 8.5 2.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein COG2 PF06148.11 ETS78770.1 - 1.5 8.9 9.3 21 5.2 2.8 3.1 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4140 PF13600.6 ETS78770.1 - 1.6 9.2 13.3 2.4 8.6 7.0 3.1 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) FapA PF03961.13 ETS78770.1 - 2.1 6.9 11.7 3.2 6.3 11.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4407 PF14362.6 ETS78770.1 - 2.9 7.2 14.4 4.3 6.6 14.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 ETS78770.1 - 3.2 6.9 13.4 4.6 6.4 13.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein AAA_23 PF13476.6 ETS78770.1 - 7.3 7.0 14.2 4.8 7.6 12.3 1.6 2 0 0 2 2 2 0 AAA domain MOZART1 PF12554.8 ETS78771.1 - 5.8e-24 83.6 0.4 6.9e-24 83.4 0.4 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DHHA1 PF02272.19 ETS78771.1 - 0.11 12.9 0.1 0.13 12.6 0.1 1.2 1 0 0 1 1 1 0 DHHA1 domain CUE PF02845.16 ETS78772.1 - 9.7e-13 47.6 0.0 1.6e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 CUE domain HA2 PF04408.23 ETS78773.1 - 2.5e-18 66.3 0.2 5.2e-18 65.3 0.2 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ETS78773.1 - 3.9e-15 56.0 0.0 4.8e-14 52.5 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ETS78773.1 - 6.9e-14 52.1 0.0 1.6e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 ETS78773.1 - 1.7e-05 25.1 0.0 4.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ETS78773.1 - 0.00011 22.0 0.1 0.00027 20.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 ETS78773.1 - 0.00036 20.4 1.0 0.0011 18.7 0.5 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 ETS78773.1 - 0.0014 19.0 0.1 0.0032 17.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 ETS78773.1 - 0.011 14.8 0.6 0.027 13.5 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 ETS78773.1 - 0.015 14.5 0.6 0.16 11.2 0.1 2.4 2 1 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 ETS78773.1 - 0.03 13.9 0.3 1.5 8.4 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 ETS78773.1 - 0.039 14.5 0.9 0.34 11.4 0.1 2.8 3 1 0 4 4 4 0 ABC transporter cobW PF02492.19 ETS78773.1 - 0.044 13.4 0.3 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 ETS78773.1 - 0.06 13.4 0.2 12 6.0 0.0 2.6 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 ETS78773.1 - 0.066 12.7 0.2 0.28 10.7 0.0 2.1 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_23 PF13476.6 ETS78773.1 - 0.15 12.5 0.4 0.29 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ETS78773.1 - 0.18 11.5 0.0 0.47 10.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SKG6 PF08693.10 ETS78775.1 - 4.7e-08 32.3 3.4 2.1e-07 30.2 3.4 2.2 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 ETS78775.1 - 0.0059 16.5 0.0 0.0059 16.5 0.0 4.9 1 1 2 3 3 3 1 TMEM154 protein family CD34_antigen PF06365.12 ETS78775.1 - 0.045 13.3 1.9 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 CD34/Podocalyxin family DUF4551 PF15087.6 ETS78775.1 - 3.3 6.4 7.7 4.1 6.1 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Utp14 PF04615.13 ETS78775.1 - 7.3 5.0 10.7 9.5 4.6 10.7 1.2 1 0 0 1 1 1 0 Utp14 protein DUF1741 PF08427.10 ETS78776.1 - 2.4e-88 295.8 0.5 4.1e-88 295.0 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Fe-S_biosyn PF01521.20 ETS78777.1 - 1.7e-19 70.0 0.0 2.2e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Phostensin_N PF13916.6 ETS78778.1 - 0.068 13.5 0.0 88 3.5 0.0 4.1 4 0 0 4 4 4 0 PP1-regulatory protein, Phostensin N-terminal Spaetzle PF16077.5 ETS78778.1 - 0.94 10.1 9.4 47 4.6 0.1 4.3 4 0 0 4 4 4 0 Spaetzle Pyr_redox_2 PF07992.14 ETS78779.1 - 7.8e-41 140.2 0.0 9.1e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS78779.1 - 4.2e-10 40.1 0.0 1.4e-06 28.7 0.1 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS78779.1 - 0.0002 21.5 0.1 0.096 12.9 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS78779.1 - 0.00079 18.6 0.7 0.62 9.1 0.0 3.0 3 0 0 3 3 3 2 FAD binding domain NAD_binding_7 PF13241.6 ETS78779.1 - 0.016 15.7 0.0 0.13 12.7 0.0 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 ETS78779.1 - 0.088 12.0 0.8 0.43 9.8 0.0 2.3 3 0 0 3 3 3 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 ETS78779.1 - 0.13 11.8 0.2 28 4.2 0.0 2.8 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AA_permease_2 PF13520.6 ETS78780.1 - 2.2e-54 185.0 55.5 2.8e-54 184.6 55.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS78780.1 - 5.5e-24 84.6 39.9 7.5e-24 84.2 39.9 1.1 1 0 0 1 1 1 1 Amino acid permease Ank_4 PF13637.6 ETS78781.1 - 8.8e-24 83.6 4.2 0.06 14.0 0.0 10.9 9 1 2 11 11 11 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS78781.1 - 1.6e-21 76.7 3.0 0.00039 20.9 0.0 7.1 2 2 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS78781.1 - 1.7e-19 67.8 7.6 0.039 14.5 0.0 11.3 11 0 0 11 11 11 4 Ankyrin repeat Ank_5 PF13857.6 ETS78781.1 - 2.3e-13 50.1 4.2 1.4 9.3 0.0 9.6 9 2 2 11 11 11 4 Ankyrin repeats (many copies) Clr5 PF14420.6 ETS78781.1 - 2.5e-08 34.0 0.0 9.5e-08 32.2 0.0 2.0 1 0 0 1 1 1 1 Clr5 domain Ank PF00023.30 ETS78781.1 - 2.6e-06 27.6 6.3 33 5.1 0.0 8.6 8 1 0 8 8 8 0 Ankyrin repeat V_ATPase_I_N PF18670.1 ETS78781.1 - 0.061 13.7 0.1 0.2 12.1 0.1 1.8 1 0 0 1 1 1 0 V-type ATPase subunit I, N-terminal domain DUF1308 PF07000.11 ETS78782.1 - 2.8e-09 37.1 0.0 3.2e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) Glyco_transf_41 PF13844.6 ETS78782.1 - 0.056 11.9 0.0 0.089 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 DUF5614 PF18474.1 ETS78782.1 - 0.11 11.8 0.1 1.2 8.4 0.1 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5614) Fascin PF06268.13 ETS78783.1 - 0.072 13.3 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Fascin domain CDH-cyt PF16010.5 ETS78784.1 - 2.6e-55 186.9 2.9 2.6e-55 186.9 2.9 1.9 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 ETS78784.1 - 1.6e-26 93.4 0.1 4.9e-26 91.8 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS78784.1 - 4.6e-22 79.1 0.4 9e-22 78.1 0.4 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS78784.1 - 1.3e-09 37.6 0.5 1.2e-06 27.9 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 ETS78784.1 - 1.2e-05 24.8 1.0 2.1e-05 24.1 1.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS78784.1 - 1.7e-05 23.7 1.5 4.4e-05 22.4 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 ETS78784.1 - 2e-05 24.0 0.3 2e-05 24.0 0.3 1.8 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS78784.1 - 2.2e-05 23.9 0.1 0.00023 20.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS78784.1 - 3.4e-05 23.6 5.3 0.00035 20.3 5.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS78784.1 - 3.9e-05 23.8 0.2 0.00016 21.8 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ETS78784.1 - 0.00016 20.9 0.1 0.0003 20.0 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 ETS78784.1 - 0.00043 19.6 0.1 0.00087 18.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 ETS78784.1 - 0.00044 19.4 0.1 0.0015 17.6 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 ETS78784.1 - 0.0056 15.6 1.1 0.0091 14.9 1.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 ETS78784.1 - 0.017 14.4 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS78784.1 - 0.018 15.6 0.6 0.018 15.6 0.6 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Aminotran_1_2 PF00155.21 ETS78785.1 - 8.3e-16 58.1 0.0 3.7e-15 56.0 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.16 ETS78786.1 - 4.3e-28 98.2 25.9 5.9e-28 97.8 25.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily COesterase PF00135.28 ETS78787.1 - 2.2e-72 244.6 0.0 3.4e-72 244.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS78787.1 - 8.4e-06 25.8 0.0 0.075 12.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Bac_rhamnosid6H PF17389.2 ETS78788.1 - 2.1e-14 53.6 0.2 1.7e-12 47.3 0.2 2.4 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Hjc PF01870.18 ETS78789.1 - 0.033 14.2 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) Cytomega_TRL10 PF06084.11 ETS78789.1 - 0.064 13.3 0.2 0.15 12.1 0.0 1.6 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein UPF0697 PF15117.6 ETS78789.1 - 0.12 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 Fungal_trans PF04082.18 ETS78790.1 - 2.1e-08 33.5 0.0 6.9e-08 31.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS78790.1 - 4.4e-08 33.1 11.9 1.4e-07 31.5 11.9 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhoU PF01895.19 ETS78790.1 - 0.056 13.9 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 PhoU domain ABC2_membrane PF01061.24 ETS78791.1 - 5.2e-81 271.1 52.3 4.3e-47 160.2 18.4 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ETS78791.1 - 3.9e-37 127.8 0.0 2.3e-17 63.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ETS78791.1 - 1.6e-27 95.2 4.5 1.5e-24 85.7 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 ETS78791.1 - 3.7e-10 39.4 35.3 8.1e-07 28.5 17.1 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 ETS78791.1 - 1e-06 29.2 0.2 4.1e-06 27.3 0.0 2.2 3 0 0 3 3 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 ETS78791.1 - 1.9e-06 28.3 0.1 0.0013 19.1 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 ETS78791.1 - 4.5e-05 23.1 0.1 0.0035 16.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ETS78791.1 - 0.00037 21.0 0.0 2 9.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ETS78791.1 - 0.00056 19.9 0.1 0.0044 16.9 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 ETS78791.1 - 0.00063 20.0 0.3 0.52 10.6 0.1 3.1 3 1 0 3 3 2 1 AAA domain AAA_29 PF13555.6 ETS78791.1 - 0.0008 19.1 0.8 0.08 12.7 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 ETS78791.1 - 0.0038 17.5 1.0 0.83 9.9 0.6 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ETS78791.1 - 0.011 15.8 0.4 1.9 8.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ETS78791.1 - 0.034 13.7 1.1 1.9 8.1 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 ETS78791.1 - 0.16 11.7 0.5 5.6 6.6 0.3 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ETS78791.1 - 0.19 11.6 0.9 3.4 7.6 0.3 2.3 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 ETS78791.1 - 0.29 10.4 1.5 4.3 6.5 0.1 2.6 3 0 0 3 3 3 0 Zeta toxin IMD PF08397.11 ETS78792.1 - 0.13 11.6 0.1 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 IRSp53/MIM homology domain MgsA_C PF12002.8 ETS78793.1 - 3.6e-59 199.4 0.0 6.8e-59 198.5 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 ETS78793.1 - 4.6e-24 84.5 0.9 9.2e-24 83.6 0.4 1.8 2 0 0 2 2 1 1 AAA C-terminal domain AAA PF00004.29 ETS78793.1 - 1.1e-13 51.8 0.1 2.2e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ETS78793.1 - 3e-08 33.6 0.0 5.5e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 ETS78793.1 - 6.1e-06 26.0 0.1 6.6e-05 22.7 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 ETS78793.1 - 2.5e-05 24.3 0.2 0.00017 21.6 0.1 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ETS78793.1 - 5.6e-05 23.6 1.1 0.018 15.5 0.0 2.9 2 2 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 ETS78793.1 - 5.7e-05 22.6 0.1 0.13 11.7 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 ETS78793.1 - 0.00038 20.7 0.2 0.0012 19.1 0.2 1.9 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 ETS78793.1 - 0.00075 18.7 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 ETS78793.1 - 0.0029 17.5 0.0 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ETS78793.1 - 0.0031 17.6 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta2 PF13177.6 ETS78793.1 - 0.0033 17.2 0.0 0.095 12.5 0.0 2.4 1 1 1 2 2 2 1 DNA polymerase III, delta subunit TIP49 PF06068.13 ETS78793.1 - 0.0057 15.9 0.0 0.0094 15.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_19 PF13245.6 ETS78793.1 - 0.0096 16.3 0.3 0.11 12.8 0.2 2.2 1 1 1 2 2 2 1 AAA domain CPT PF07931.12 ETS78793.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 ETS78793.1 - 0.017 15.1 1.2 0.32 11.0 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SKI PF01202.22 ETS78793.1 - 0.038 14.1 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_24 PF13479.6 ETS78793.1 - 0.043 13.5 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 ETS78793.1 - 0.078 13.1 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_23 PF13476.6 ETS78793.1 - 0.11 13.0 0.1 0.18 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ETS78793.1 - 0.11 12.2 0.1 0.29 10.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 ETS78793.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 ETS78793.1 - 0.15 12.5 0.0 0.53 10.8 0.0 1.9 2 0 0 2 2 1 0 ABC transporter TniB PF05621.11 ETS78793.1 - 0.16 11.3 0.0 0.34 10.3 0.0 1.5 1 1 0 1 1 1 0 Bacterial TniB protein TRAF6_Z2 PF18048.1 ETS78793.1 - 0.19 11.9 2.7 0.34 11.0 2.7 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 ATPase_2 PF01637.18 ETS78793.1 - 0.2 11.6 0.2 1.6 8.6 0.1 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Utp12 PF04003.12 ETS78794.1 - 1.8e-24 86.1 0.1 2.6e-24 85.6 0.1 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Big_7 PF17957.1 ETS78794.1 - 0.063 14.1 2.9 0.33 11.8 0.6 2.4 2 0 0 2 2 2 0 Bacterial Ig domain SDA1 PF05285.12 ETS78794.1 - 9.3 5.6 29.8 1.9 7.8 1.3 2.1 2 0 0 2 2 2 0 SDA1 Bromodomain PF00439.25 ETS78795.1 - 4.3e-31 106.8 0.0 1.1e-16 60.7 0.0 2.6 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 ETS78795.1 - 1.9e-11 44.0 1.7 4.5e-11 42.7 1.7 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation FOXP-CC PF16159.5 ETS78795.1 - 0.068 13.8 3.8 7.7 7.2 0.4 2.9 2 0 0 2 2 2 0 FOXP coiled-coil domain Ninjurin PF04923.12 ETS78796.1 - 4.2 7.4 7.0 6.7 6.7 0.0 3.5 3 1 0 3 3 3 0 Ninjurin BRCA-2_helical PF09169.10 ETS78798.1 - 0.0021 17.7 0.6 0.0037 17.0 0.6 1.3 1 0 0 1 1 1 1 BRCA2, helical DUF1992 PF09350.10 ETS78799.1 - 2.1e-21 75.9 0.2 5.2e-21 74.6 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) IMUP PF15761.5 ETS78799.1 - 0.068 13.9 4.2 0.33 11.7 4.2 2.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein Rotamase_2 PF13145.6 ETS78799.1 - 3.1 8.6 7.0 0.92 10.4 2.8 2.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain AcetylCoA_hydro PF02550.15 ETS78800.1 - 6.8e-45 153.5 0.0 1.1e-44 152.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 ETS78800.1 - 3.5e-41 140.7 0.0 5.3e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain MFS_1 PF07690.16 ETS78801.1 - 7.6e-17 61.3 33.5 7.6e-17 61.3 33.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ETS78801.1 - 1e-07 31.8 8.2 1e-07 31.8 8.2 2.7 4 1 0 4 4 4 1 Ion channel regulatory protein UNC-93 TadE PF07811.12 ETS78801.1 - 0.29 11.5 4.0 4.6 7.6 0.0 3.7 3 0 0 3 3 3 0 TadE-like protein RasGEF PF00617.19 ETS78802.1 - 4.7e-52 176.7 0.0 1e-51 175.7 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ETS78802.1 - 7.6e-16 58.3 0.0 3.3e-15 56.2 0.0 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.6 ETS78802.1 - 9.4e-07 28.6 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ETS78802.1 - 0.00014 21.4 0.0 0.00029 20.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain DUF1924 PF09086.11 ETS78802.1 - 0.13 12.6 0.0 0.72 10.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) Jacalin PF01419.17 ETS78803.1 - 0.00038 20.4 0.0 0.00065 19.6 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Sulfatase PF00884.23 ETS78804.1 - 4.2e-53 180.7 2.5 5.5e-53 180.4 2.5 1.1 1 0 0 1 1 1 1 Sulfatase HET PF06985.11 ETS78806.1 - 2.2e-24 86.5 0.0 4.5e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AA_permease_2 PF13520.6 ETS78807.1 - 8.7e-53 179.7 47.1 1.1e-52 179.4 47.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS78807.1 - 1.1e-18 67.1 36.5 1.4e-18 66.7 36.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF647 PF04884.14 ETS78808.1 - 1.1e-101 339.5 0.8 1.3e-101 339.3 0.8 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Cyto_heme_lyase PF01265.17 ETS78809.1 - 5e-44 151.1 18.4 3.7e-42 144.9 0.8 3.2 1 1 2 3 3 3 3 Cytochrome c/c1 heme lyase HET PF06985.11 ETS78810.1 - 9.9e-24 84.4 0.4 1.8e-23 83.5 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) peroxidase PF00141.23 ETS78811.1 - 1.1e-21 77.6 0.3 1.8e-21 76.9 0.3 1.3 1 0 0 1 1 1 1 Peroxidase PSI_PSAK PF01241.18 ETS78811.1 - 0.16 12.0 0.0 0.99 9.5 0.0 2.2 2 0 0 2 2 2 0 Photosystem I psaG / psaK SNF2_N PF00176.23 ETS78812.1 - 5.1e-59 199.7 0.0 7.4e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS78812.1 - 7.5e-12 45.6 0.3 2.5e-11 43.9 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ETS78812.1 - 1.4e-08 34.7 0.0 3.9e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ETS78812.1 - 4.6e-07 30.0 0.0 9.4e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 ETS78812.1 - 0.012 15.6 9.3 0.025 14.5 9.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain TgMIC1 PF11476.8 ETS78812.1 - 0.068 12.9 0.1 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 GAGA PF09237.11 ETS78812.1 - 0.15 11.9 1.2 0.43 10.4 1.2 1.7 1 0 0 1 1 1 0 GAGA factor YdjO PF14169.6 ETS78812.1 - 0.18 11.5 1.4 0.51 10.1 1.4 1.7 1 0 0 1 1 1 0 Cold-inducible protein YdjO zf-UDP PF14569.6 ETS78812.1 - 0.4 10.8 3.3 1.1 9.4 3.3 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger Prok-RING_4 PF14447.6 ETS78812.1 - 0.67 9.9 7.9 1.5 8.7 7.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-piccolo PF05715.13 ETS78812.1 - 1.8 8.8 6.3 3.8 7.7 6.3 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger zf-C3HC4_2 PF13923.6 ETS78812.1 - 1.9 8.4 4.7 1.1 9.2 1.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ETS78812.1 - 2.2 8.2 9.6 5.6 6.9 9.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NACHT PF05729.12 ETS78813.1 - 5.9e-10 39.3 0.1 2e-09 37.6 0.1 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS78813.1 - 4.7e-06 27.1 0.0 1.9e-05 25.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain zf-C2H2_jaz PF12171.8 ETS78813.1 - 7e-06 26.2 10.0 0.015 15.6 0.1 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ETS78813.1 - 5.2e-05 23.5 5.2 0.29 11.6 2.2 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ETS78813.1 - 0.0001 22.6 0.2 0.0001 22.6 0.2 4.6 4 1 0 4 4 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ETS78813.1 - 0.00035 20.5 11.2 0.0037 17.2 3.9 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ETS78813.1 - 0.00036 20.8 30.9 0.0013 19.1 5.3 5.4 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS78813.1 - 0.0011 19.6 23.1 0.012 16.4 4.2 5.1 4 0 0 4 4 4 2 C2H2-type zinc finger AAA_33 PF13671.6 ETS78813.1 - 0.0015 18.7 0.1 0.043 14.0 0.1 3.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ETS78813.1 - 0.014 15.6 0.0 0.058 13.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ETS78813.1 - 0.071 12.3 0.0 0.41 9.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain zf_PR_Knuckle PF18445.1 ETS78813.1 - 0.079 12.8 1.1 3.6 7.5 0.3 2.5 2 0 0 2 2 2 0 PR zinc knuckle motif AAA_18 PF13238.6 ETS78813.1 - 0.1 13.1 0.0 0.62 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ETS78813.1 - 0.16 12.4 0.0 0.62 10.5 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-C2H2_11 PF16622.5 ETS78813.1 - 0.49 10.2 3.8 2.5 8.0 3.8 2.4 1 0 0 1 1 1 0 zinc-finger C2H2-type WSC PF01822.19 ETS78814.1 - 2.1e-12 47.0 3.5 6.6e-12 45.5 3.5 1.9 1 0 0 1 1 1 1 WSC domain FXR_C3 PF16097.5 ETS78815.1 - 0.12 13.1 0.0 0.22 12.2 0.0 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 3 LysM PF01476.20 ETS78817.1 - 8.7e-12 44.9 0.0 2.5e-05 24.2 0.0 3.5 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.19 ETS78817.1 - 7.6e-05 23.1 6.4 7.6e-05 23.1 6.4 3.6 2 1 0 2 2 2 1 Chitin recognition protein Glyco_hydro_18 PF00704.28 ETS78818.1 - 6.1e-44 151.0 0.9 1e-43 150.3 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 BIRC6 PF12356.8 ETS78819.1 - 0.26 10.7 1.6 0.37 10.2 1.1 1.5 2 0 0 2 2 2 0 Baculoviral IAP repeat-containing protein 6 adh_short PF00106.25 ETS78820.1 - 1.7e-37 128.8 2.5 2.4e-37 128.3 2.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS78820.1 - 6.4e-24 84.8 2.7 1.6e-23 83.5 2.4 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 ETS78820.1 - 1e-06 28.3 0.0 2e-06 27.4 0.0 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 ETS78820.1 - 4.8e-05 23.3 0.1 8.3e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS78820.1 - 0.00057 19.4 0.1 0.00079 19.0 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 ETS78820.1 - 0.0032 17.3 1.1 0.0067 16.3 1.1 1.5 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.17 ETS78820.1 - 0.0092 15.1 0.1 0.084 12.0 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_2 PF03446.15 ETS78820.1 - 0.011 15.9 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 ETS78820.1 - 0.05 13.5 0.1 0.082 12.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ETS78820.1 - 0.066 13.8 0.4 0.18 12.4 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans_2 PF11951.8 ETS78821.1 - 6.1e-48 163.6 3.3 9.3e-48 162.9 3.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS78821.1 - 6.8e-07 29.3 7.1 1.3e-06 28.4 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BBE PF08031.12 ETS78822.1 - 0.016 15.3 0.0 0.043 13.9 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like FAD_binding_4 PF01565.23 ETS78822.1 - 0.044 13.5 0.0 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain DUF3328 PF11807.8 ETS78823.1 - 1.3e-43 149.4 1.2 2e-43 148.7 1.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_23 PF13489.6 ETS78825.1 - 2.8e-14 53.3 0.0 4e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS78825.1 - 2.3e-13 50.6 0.0 5.5e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS78825.1 - 3.4e-12 46.4 0.0 4.2e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS78825.1 - 5.3e-12 46.3 0.0 1e-11 45.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS78825.1 - 1.3e-09 38.6 0.0 3.6e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 ETS78825.1 - 4.8e-06 25.7 0.0 6e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 ETS78825.1 - 0.0013 18.3 0.1 0.0024 17.5 0.1 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.20 ETS78825.1 - 0.02 14.0 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.18 ETS78825.1 - 0.022 14.1 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 ETS78825.1 - 0.17 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Arylsulfotran_2 PF14269.6 ETS78826.1 - 7.1e-61 206.2 0.8 1.1e-60 205.5 0.8 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 ETS78826.1 - 3.2e-23 82.3 0.2 8.7e-23 80.8 0.2 1.6 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) adh_short_C2 PF13561.6 ETS78827.1 - 6.9e-41 140.3 0.0 8.6e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS78827.1 - 3.5e-31 108.2 0.0 5e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS78827.1 - 1e-07 32.0 0.0 1.5e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF4733 PF15878.5 ETS78827.1 - 0.011 16.2 0.0 0.021 15.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4733) GDP_Man_Dehyd PF16363.5 ETS78827.1 - 0.014 14.8 0.0 0.056 12.8 0.0 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase MadM PF03818.13 ETS78827.1 - 0.075 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit Abhydrolase_3 PF07859.13 ETS78828.1 - 1.1e-42 146.3 0.1 1.9e-30 106.3 0.2 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 ETS78828.1 - 9.1e-06 24.8 0.1 1.5e-05 24.1 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ETS78828.1 - 3.4e-05 23.4 0.0 0.0022 17.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 ETS78828.1 - 0.0027 18.3 1.2 0.0046 17.6 1.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 ETS78828.1 - 0.0087 15.6 0.1 0.023 14.3 0.1 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 ETS78828.1 - 0.068 11.8 0.0 0.096 11.3 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Ank_2 PF12796.7 ETS78829.1 - 1.7e-113 371.4 7.5 1.3e-17 64.2 0.1 10.1 2 1 9 11 11 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS78829.1 - 6.2e-112 364.7 29.2 4.5e-12 46.2 0.1 14.5 3 2 13 16 16 16 14 Ankyrin repeats (many copies) Ank PF00023.30 ETS78829.1 - 9.9e-88 285.1 31.0 3.5e-07 30.4 0.0 16.7 16 1 1 17 17 17 14 Ankyrin repeat Ank_3 PF13606.6 ETS78829.1 - 4.5e-87 275.5 8.6 1.1e-05 25.4 0.0 18.3 18 0 0 18 18 18 13 Ankyrin repeat Ank_5 PF13857.6 ETS78829.1 - 3.4e-81 266.2 38.8 2.2e-12 47.0 0.2 15.5 4 2 13 17 17 17 14 Ankyrin repeats (many copies) HeLo PF14479.6 ETS78829.1 - 5.1e-20 72.2 0.7 2.5e-19 69.9 0.0 2.6 2 1 0 2 2 2 1 Prion-inhibition and propagation NACHT PF05729.12 ETS78829.1 - 5.3e-12 46.0 0.0 1.1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Fer4_14 PF13394.6 ETS78829.1 - 0.027 14.6 0.1 8.2 6.6 0.0 4.2 4 0 0 4 4 4 0 4Fe-4S single cluster domain Orn_Arg_deC_N PF02784.16 ETS78829.1 - 0.03 13.7 0.2 19 4.5 0.0 3.9 4 1 1 5 5 5 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain NB-ARC PF00931.22 ETS78829.1 - 0.16 11.1 0.0 0.66 9.1 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain DUF445 PF04286.12 ETS78829.1 - 0.22 11.3 1.0 10 5.8 1.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF445) WD40 PF00400.32 ETS78830.1 - 1.2e-53 177.9 9.1 1e-08 35.6 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS78830.1 - 7e-23 80.7 0.0 0.013 15.8 0.0 7.3 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ETS78830.1 - 2.4e-12 47.1 0.0 6.9e-07 29.3 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A HET PF06985.11 ETS78830.1 - 1.2e-10 42.0 3.4 1e-07 32.4 0.1 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ge1_WD40 PF16529.5 ETS78830.1 - 5.7e-10 38.7 1.6 0.0095 14.9 0.0 5.7 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 ETS78830.1 - 1.5e-08 34.8 0.0 3.4e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS78830.1 - 1.6e-07 31.9 0.2 3.5e-07 30.8 0.2 1.6 1 0 0 1 1 1 1 AAA ATPase domain WD40_like PF17005.5 ETS78830.1 - 4.9e-07 29.4 0.0 0.052 12.9 0.0 3.7 3 1 1 4 4 4 2 WD40-like domain BBS2_Mid PF14783.6 ETS78830.1 - 0.00065 19.7 0.0 0.62 10.1 0.0 3.4 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Proteasome_A_N PF10584.9 ETS78830.1 - 0.0013 18.4 0.2 25 4.7 0.0 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature PD40 PF07676.12 ETS78830.1 - 0.0024 17.8 5.4 30 4.7 0.0 5.9 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 ETS78830.1 - 0.003 16.1 0.1 0.16 10.4 0.1 2.5 1 1 1 2 2 2 2 Cytochrome D1 heme domain AAA_22 PF13401.6 ETS78830.1 - 0.0038 17.5 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 ETS78830.1 - 0.0061 15.8 0.2 0.048 12.9 0.1 2.1 1 1 0 2 2 2 1 KAP family P-loop domain Nup160 PF11715.8 ETS78830.1 - 0.0095 14.6 1.8 2 7.0 0.0 4.0 1 1 3 5 5 5 1 Nucleoporin Nup120/160 DUF815 PF05673.13 ETS78830.1 - 0.016 14.4 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Frtz PF11768.8 ETS78830.1 - 0.032 12.5 0.0 0.44 8.8 0.0 2.5 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz RNA_helicase PF00910.22 ETS78830.1 - 0.068 13.6 0.3 1.1 9.7 0.0 3.2 3 1 0 3 3 2 0 RNA helicase Thymidylate_kin PF02223.17 ETS78830.1 - 0.11 12.1 0.0 0.33 10.6 0.0 1.8 1 0 0 1 1 1 0 Thymidylate kinase FAD_binding_3 PF01494.19 ETS78831.1 - 1.1e-11 44.7 0.1 4.1e-06 26.3 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ETS78831.1 - 4.7e-05 22.8 0.0 7.2e-05 22.2 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS78831.1 - 0.00037 19.8 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 ETS78831.1 - 0.0015 17.7 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ETS78831.1 - 0.0016 18.7 0.0 0.0036 17.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ETS78831.1 - 0.0025 16.6 0.0 0.0082 14.9 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 ETS78831.1 - 0.0051 16.5 0.1 0.0096 15.5 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS78831.1 - 0.0093 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS78831.1 - 0.047 12.8 0.0 0.064 12.3 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 ETS78831.1 - 0.17 10.9 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein LOR PF04525.12 ETS78832.1 - 2e-10 40.6 0.4 5e-10 39.3 0.4 1.6 1 1 0 1 1 1 1 LURP-one-related SH3_10 PF17902.1 ETS78832.1 - 0.035 14.2 0.0 0.24 11.5 0.0 2.3 2 0 0 2 2 2 0 SH3 domain Lactonase PF10282.9 ETS78833.1 - 1.8e-64 218.2 0.1 2.3e-64 217.8 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 ETS78833.1 - 0.005 16.4 0.0 0.037 13.6 0.0 2.3 1 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Peptidase_S49_N PF08496.10 ETS78834.1 - 1 9.4 5.7 1.6 8.7 5.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DAO PF01266.24 ETS78835.1 - 1.4e-33 117.0 0.1 1.5e-33 116.8 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS78835.1 - 9.3e-06 25.8 0.0 3.9e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS78835.1 - 1.8e-05 24.0 0.0 3.9e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS78835.1 - 0.00015 21.1 0.0 0.0021 17.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS78835.1 - 0.00034 20.0 0.0 0.00066 19.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 ETS78835.1 - 0.0014 19.0 0.0 0.004 17.6 0.0 1.9 2 1 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.27 ETS78835.1 - 0.0064 17.0 0.0 0.019 15.5 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ETS78835.1 - 0.0096 15.2 0.0 0.026 13.8 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ETS78835.1 - 0.015 14.5 0.0 0.094 11.9 0.0 2.1 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 ETS78835.1 - 0.017 14.2 0.0 0.053 12.6 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 ETS78835.1 - 0.093 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ETS78835.1 - 0.17 11.9 0.0 0.61 10.2 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase p450 PF00067.22 ETS78836.1 - 4.3e-84 282.9 0.0 5e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HPP PF04982.13 ETS78837.1 - 1.5e-41 141.4 7.7 1.5e-41 141.4 7.7 1.7 2 0 0 2 2 2 1 HPP family DUF4064 PF13273.6 ETS78837.1 - 0.72 10.2 3.6 0.34 11.2 0.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF3712 PF12505.8 ETS78838.1 - 3e-12 46.9 0.9 1.2e-09 38.5 0.3 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3712) LEA_2 PF03168.13 ETS78838.1 - 0.0003 21.3 3.4 24 5.6 0.0 6.0 6 1 1 7 7 7 1 Late embryogenesis abundant protein DUF974 PF06159.13 ETS78839.1 - 6.8e-79 265.1 0.0 8.7e-79 264.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DENN PF02141.21 ETS78840.1 - 1.3e-58 198.0 0.4 2.9e-58 196.9 0.0 1.7 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.19 ETS78840.1 - 5.1e-15 55.2 0.1 1.4e-14 53.8 0.1 1.8 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 ETS78840.1 - 1.5e-14 54.5 0.0 4.4e-14 53.0 0.0 1.9 1 0 0 1 1 1 1 uDENN domain C1_2 PF03107.16 ETS78840.1 - 0.0013 19.0 2.9 0.0026 18.0 2.9 1.5 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 ETS78840.1 - 0.054 13.4 7.2 0.1 12.5 7.2 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SPA PF08616.10 ETS78840.1 - 0.2 11.6 0.0 0.45 10.5 0.0 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis PHD PF00628.29 ETS78840.1 - 0.61 10.0 8.2 1.3 8.9 8.2 1.6 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 ETS78840.1 - 4.1 7.6 7.0 8.7 6.5 7.0 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger PPI_Ypi1 PF07491.11 ETS78841.1 - 2e-24 85.2 0.0 2e-24 85.2 0.0 2.8 2 1 1 3 3 3 1 Protein phosphatase inhibitor Nucleo_P87 PF07267.11 ETS78841.1 - 0.51 9.1 1.3 0.63 8.8 1.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 ETS78841.1 - 0.52 8.5 1.7 0.66 8.2 1.7 1.1 1 0 0 1 1 1 0 CDC45-like protein CCP_MauG PF03150.14 ETS78842.1 - 0.03 15.0 0.1 0.035 14.7 0.1 1.0 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase GAPES4 PF17157.4 ETS78842.1 - 0.082 13.3 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain Aldo_ket_red PF00248.21 ETS78843.1 - 8.5e-59 199.1 0.0 9.6e-59 199.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PIF1 PF05970.14 ETS78846.1 - 0.18 11.0 0.1 0.18 10.9 0.1 1.1 1 0 0 1 1 1 0 PIF1-like helicase Tannase PF07519.11 ETS78847.1 - 9.6e-65 219.3 0.1 1.3e-64 218.9 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 ETS78847.1 - 0.06 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 EKLF_TAD2 PF16833.5 ETS78847.1 - 0.21 11.6 0.1 0.21 11.6 0.1 1.9 2 0 0 2 2 2 0 Erythroid krueppel-like transcription factor, transactivation 2 HET PF06985.11 ETS78848.1 - 3.3e-35 121.6 0.2 6.2e-35 120.7 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3328 PF11807.8 ETS78849.1 - 7.5e-38 130.5 0.8 1.9e-37 129.2 0.9 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) Methyltransf_25 PF13649.6 ETS78851.1 - 1.1e-06 29.2 0.0 1.8e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS78851.1 - 1.9e-05 25.3 0.0 2.9e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS78851.1 - 2.8e-05 24.7 0.0 4.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS78851.1 - 0.0049 16.7 0.0 0.008 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ETS78851.1 - 0.018 14.3 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain MFS_5 PF05631.14 ETS78852.1 - 2.5e-43 148.4 4.9 3.1e-43 148.0 4.9 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 ETS78852.1 - 4.2e-10 39.1 13.8 9.1e-10 38.0 4.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS78852.1 - 1e-05 24.6 5.8 2.7e-05 23.2 5.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 ETS78852.1 - 0.00051 19.0 0.0 0.0029 16.5 0.0 1.9 1 1 0 1 1 1 1 MFS_1 like family ketoacyl-synt PF00109.26 ETS78853.1 - 2e-62 211.1 0.0 4.7e-62 209.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ETS78853.1 - 1.3e-55 188.1 0.0 3e-55 186.9 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 ETS78853.1 - 4e-50 170.7 0.0 6.9e-50 170.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ETS78853.1 - 4.1e-49 167.8 0.0 9.3e-49 166.6 0.0 1.6 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ETS78853.1 - 1.5e-36 125.0 0.0 3.9e-36 123.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 ETS78853.1 - 3.8e-17 63.6 0.0 2.2e-16 61.1 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 ETS78853.1 - 3.9e-15 56.3 0.0 1.6e-14 54.3 0.0 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 ETS78853.1 - 8.8e-12 44.9 0.0 3.2e-11 43.1 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.26 ETS78853.1 - 3.4e-09 36.8 0.0 8.1e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 ETS78853.1 - 1.5e-07 31.2 0.1 5.7e-07 29.3 0.0 2.0 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 ETS78853.1 - 0.00021 21.2 0.0 0.00067 19.5 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 ETS78853.1 - 0.00023 21.5 0.1 0.00086 19.6 0.1 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 ETS78853.1 - 0.00041 19.8 0.2 0.00097 18.6 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 ETS78853.1 - 0.019 14.8 0.2 0.051 13.4 0.2 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.22 ETS78855.1 - 3.7e-66 223.8 0.0 4.8e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3176 PF11374.8 ETS78856.1 - 1.5e-26 92.7 3.1 3.3e-26 91.6 3.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) RTA1 PF04479.13 ETS78857.1 - 8.1e-56 188.9 10.8 8.1e-56 188.9 10.8 1.6 2 0 0 2 2 2 1 RTA1 like protein DUF4383 PF14325.6 ETS78857.1 - 0.62 10.4 11.8 0.098 12.9 7.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4383) AltA1 PF16541.5 ETS78858.1 - 0.036 14.9 0.0 0.048 14.5 0.0 1.1 1 0 0 1 1 1 0 Alternaria alternata allergen 1 L51_S25_CI-B8 PF05047.16 ETS78859.1 - 8e-20 70.5 0.0 1.5e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MMR_HSR1 PF01926.23 ETS78860.1 - 1.6e-05 24.9 0.0 0.27 11.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase C2 PF00168.30 ETS78861.1 - 5e-30 103.8 0.0 1.1e-16 60.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain IMS PF00817.20 ETS78863.1 - 1.3e-40 138.8 0.0 2.7e-40 137.8 0.0 1.5 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 ETS78863.1 - 1.5e-15 57.9 0.3 3.9e-14 53.3 0.2 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 ETS78863.1 - 0.004 17.4 0.0 0.0099 16.2 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif DNA_RNApol_7kD PF03604.13 ETS78863.1 - 0.013 15.1 0.2 0.033 13.9 0.2 1.6 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zf_UBZ PF18439.1 ETS78863.1 - 0.17 11.5 0.3 0.34 10.5 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger DLH PF01738.18 ETS78864.1 - 2.4e-23 82.8 0.0 3.5e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 ETS78864.1 - 0.00073 19.2 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 ETS78864.1 - 0.0013 19.4 0.1 0.0015 19.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 ETS78864.1 - 0.0025 17.8 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 ETS78864.1 - 0.075 11.7 0.0 0.17 10.5 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) HSP70 PF00012.20 ETS78865.1 - 1.1e-258 859.4 4.0 1.3e-258 859.2 4.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ETS78865.1 - 2e-15 56.5 0.1 2.1e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 ETS78865.1 - 0.0035 17.1 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 ETS78865.1 - 0.023 14.0 0.1 0.046 13.0 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 ETS78865.1 - 0.039 13.4 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 ETS78865.1 - 0.045 14.2 3.1 7.5 7.0 0.1 3.4 3 2 0 3 3 3 0 Cell division protein FtsA PMBR PF09373.10 ETS78865.1 - 0.42 10.9 0.1 0.42 10.9 0.1 2.6 3 0 0 3 3 3 0 Pseudomurein-binding repeat DUF3128 PF11326.8 ETS78866.1 - 1.9e-23 82.6 0.3 1.9e-23 82.6 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) RNA12 PF10443.9 ETS78867.1 - 7.8e-160 532.4 1.0 7.8e-160 532.4 1.0 1.7 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.22 ETS78867.1 - 6.7e-06 25.8 0.0 2.4e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 ETS78867.1 - 0.00044 20.2 0.2 0.0056 16.6 0.2 2.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF2487 PF10673.9 ETS78867.1 - 0.0029 17.6 0.0 0.0066 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) CENP-C_C PF11699.8 ETS78868.1 - 3.1e-33 113.8 0.5 5.1e-33 113.1 0.5 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 ETS78868.1 - 1.7e-26 93.5 6.5 1.7e-26 93.5 6.5 5.1 1 1 2 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 ETS78868.1 - 2e-05 24.2 0.0 5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 ETS78868.1 - 0.016 14.9 0.0 0.043 13.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) RNase_HII PF01351.18 ETS78869.1 - 3.1e-46 157.7 0.0 1.6e-40 139.0 0.0 2.1 2 0 0 2 2 2 2 Ribonuclease HII RHD3 PF05879.12 ETS78870.1 - 0 1050.6 0.0 0 1050.4 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 ETS78870.1 - 1.9e-07 30.6 0.1 3.2e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 ETS78870.1 - 3.1e-06 27.4 0.0 5.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 ETS78870.1 - 5.3e-05 23.3 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 ETS78870.1 - 0.00077 19.7 0.1 0.0044 17.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Cys_Met_Meta_PP PF01053.20 ETS78870.1 - 0.036 12.6 0.1 0.057 11.9 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme HlyIII PF03006.20 ETS78871.1 - 1.2e-54 185.4 15.1 1.5e-54 185.1 15.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF975 PF06161.11 ETS78871.1 - 0.082 12.7 3.9 0.16 11.8 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF975) COX2_TM PF02790.15 ETS78871.1 - 1.1 9.4 3.9 7.6 6.8 0.3 2.9 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain SPC12 PF06645.13 ETS78871.1 - 5.8 7.1 9.8 0.53 10.4 1.4 3.1 3 1 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) TFIID_30kDa PF03540.13 ETS78872.1 - 2.3e-24 85.1 0.3 3.5e-24 84.5 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 ETS78872.1 - 0.049 14.2 0.9 0.11 13.1 0.9 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Chisel PF15355.6 ETS78872.1 - 5.7 7.2 7.7 12 6.2 0.4 2.3 2 0 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel Ribosomal_S19 PF00203.21 ETS78873.1 - 2.1e-27 94.8 0.0 2.5e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 GMC_oxred_N PF00732.19 ETS78874.1 - 4.5e-55 187.1 0.0 5.7e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS78874.1 - 1.2e-32 113.5 0.0 2.1e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ETS78874.1 - 0.00014 21.1 0.1 0.00039 19.6 0.0 1.8 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ETS78874.1 - 0.00015 21.9 0.0 0.00048 20.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS78874.1 - 0.0033 17.1 0.1 0.0096 15.5 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 ETS78874.1 - 0.0069 15.7 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 ETS78874.1 - 0.022 13.8 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 ETS78874.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 ETS78874.1 - 0.068 13.7 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS78874.1 - 0.086 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2776 PF10951.8 ETS78874.1 - 0.11 11.7 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) TrkA_N PF02254.18 ETS78874.1 - 0.14 12.4 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 ETS78874.1 - 0.14 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein LicD PF04991.13 ETS78875.1 - 1.8e-22 80.6 3.9 2.2e-16 60.7 0.9 2.2 1 1 1 2 2 2 2 LicD family WLM PF08325.10 ETS78876.1 - 4.3e-51 173.7 0.2 7.3e-51 173.0 0.0 1.4 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.17 ETS78876.1 - 0.00043 20.4 2.4 0.00077 19.6 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF45 ubiquitin PF00240.23 ETS78876.1 - 0.0061 16.3 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family SprT-like PF10263.9 ETS78876.1 - 0.16 11.9 2.6 0.31 10.9 2.6 1.6 1 1 0 1 1 1 0 SprT-like family Rad60-SLD PF11976.8 ETS78876.1 - 0.16 11.8 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ER_lumen_recept PF00810.18 ETS78877.1 - 1.7e-53 181.4 7.1 2.8e-53 180.7 7.1 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 ETS78877.1 - 0.17 11.7 0.2 0.17 11.7 0.2 3.6 4 1 1 5 5 5 0 PQ loop repeat Insulin_TMD PF17870.1 ETS78878.1 - 3.6 7.7 4.5 0.8 9.8 0.7 1.8 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Ribosomal_S8e PF01201.22 ETS78879.1 - 1.7e-54 183.7 1.3 2.1e-54 183.4 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e RabGAP-TBC PF00566.18 ETS78880.1 - 8.4e-46 156.3 0.3 8.4e-46 156.3 0.3 3.1 3 1 0 3 3 3 1 Rab-GTPase-TBC domain Cnn_1N PF07989.11 ETS78880.1 - 0.00092 19.3 8.8 0.00092 19.3 8.8 3.9 2 1 1 3 3 3 1 Centrosomin N-terminal motif 1 Jnk-SapK_ap_N PF09744.9 ETS78880.1 - 0.008 16.4 19.7 0.008 16.4 19.7 3.9 3 2 1 4 4 4 1 JNK_SAPK-associated protein-1 HALZ PF02183.18 ETS78880.1 - 0.84 9.9 23.5 0.042 14.1 1.3 3.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper TolA_bind_tri PF16331.5 ETS78880.1 - 1 9.5 12.9 0.15 12.1 4.4 2.9 1 1 0 2 2 2 0 TolA binding protein trimerisation FlaC_arch PF05377.11 ETS78880.1 - 4.7 7.7 14.9 3.5 8.1 4.8 3.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 ETS78880.1 - 6.8 6.7 15.8 6.3 6.8 4.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ILVD_EDD PF00920.21 ETS78881.1 - 1e-153 512.7 0.0 1.2e-153 512.4 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family DUF1611_N PF17396.2 ETS78881.1 - 0.094 13.0 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain DUF218 PF02698.17 ETS78882.1 - 2.9e-06 27.3 0.0 8.1e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 DUF218 domain p450 PF00067.22 ETS78883.1 - 1.2e-16 60.5 0.0 3.3e-09 36.0 0.0 2.5 3 0 0 3 3 3 2 Cytochrome P450 Fer2 PF00111.27 ETS78883.1 - 3.4e-10 39.7 1.2 5.9e-10 39.0 1.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 ETS78883.1 - 4.4e-07 30.5 0.0 0.0005 20.7 0.0 3.8 4 0 0 4 4 4 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ETS78883.1 - 0.00025 21.3 0.0 0.00046 20.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ETS78883.1 - 0.16 12.1 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Pept_tRNA_hydro PF01195.19 ETS78884.1 - 1.5e-25 90.1 0.0 4.5e-25 88.6 0.0 1.7 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase AMP-binding PF00501.28 ETS78885.1 - 2.9e-68 230.4 0.0 4.9e-68 229.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ETS78885.1 - 1.2e-41 142.6 0.1 2.6e-41 141.5 0.1 1.6 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 ETS78885.1 - 1.1e-06 28.9 0.0 3.9e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 ETS78885.1 - 5.3e-06 26.1 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GPS2_interact PF15784.5 ETS78885.1 - 0.1 13.0 1.0 0.32 11.5 1.0 1.8 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain 3Beta_HSD PF01073.19 ETS78885.1 - 0.14 11.2 0.2 0.33 9.9 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Aminotran_5 PF00266.19 ETS78886.1 - 1.8e-42 145.6 0.0 3.3e-42 144.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ETS78886.1 - 0.0028 16.2 0.0 0.0042 15.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme TPR_12 PF13424.6 ETS78887.1 - 2.4e-11 43.8 2.7 2.3e-08 34.2 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat NB-ARC PF00931.22 ETS78887.1 - 4.2e-08 32.7 0.0 3.7e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain TPR_10 PF13374.6 ETS78887.1 - 1.4e-05 24.8 5.4 0.57 10.1 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ETS78887.1 - 0.0016 18.4 0.4 0.6 10.4 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS78887.1 - 0.0026 17.2 2.4 0.0047 16.4 2.4 1.4 1 0 0 1 1 1 1 MalT-like TPR region TPR_1 PF00515.28 ETS78887.1 - 0.004 16.9 0.4 0.035 13.9 0.0 2.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ETS78887.1 - 0.031 14.8 5.0 0.49 10.9 0.0 4.8 5 1 1 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS78887.1 - 0.044 14.0 0.0 0.17 12.1 0.0 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 AAA_16 PF13191.6 ETS78887.1 - 0.053 13.9 4.9 0.11 12.9 0.5 3.8 3 1 0 3 3 3 0 AAA ATPase domain TPR_8 PF13181.6 ETS78887.1 - 0.13 12.5 0.0 3.2 8.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M19 PF01244.21 ETS78889.1 - 3.2e-92 309.1 0.0 1.5e-46 159.1 0.0 2.0 2 0 0 2 2 2 2 Membrane dipeptidase (Peptidase family M19) Peptidase_C12 PF01088.21 ETS78890.1 - 2.5e-40 138.5 0.0 2.7e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 2OG-FeII_Oxy PF03171.20 ETS78891.1 - 7.4e-10 39.2 0.0 1.5e-09 38.3 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pico_P1A PF02226.16 ETS78891.1 - 0.18 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) Peptidase_S8 PF00082.22 ETS78894.1 - 9.9e-14 51.3 0.0 9.9e-14 51.3 0.0 2.0 2 0 0 2 2 2 1 Subtilase family Ank_2 PF12796.7 ETS78894.1 - 8.8e-05 23.0 0.1 0.012 16.2 0.0 3.2 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS78894.1 - 0.00087 19.6 0.1 5.1 7.5 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS78894.1 - 0.0016 18.8 0.1 7.4 7.2 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 ETS78894.1 - 0.0047 17.3 0.1 16 6.5 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeat DUF4874 PF16173.5 ETS78894.1 - 0.13 12.0 0.1 4.2 7.0 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4874) RNase_H2_suC PF08615.11 ETS78894.1 - 2.8 8.1 7.7 0.82 9.8 2.8 2.4 2 1 1 3 3 3 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Ank_2 PF12796.7 ETS78896.1 - 6.9e-139 452.8 32.7 1.2e-14 54.7 1.0 14.7 3 2 15 18 18 18 17 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS78896.1 - 2.2e-104 340.6 20.4 2.1e-07 31.3 0.0 22.1 13 6 11 24 24 24 19 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS78896.1 - 2.8e-83 263.8 18.7 0.00029 21.1 0.0 27.8 28 0 0 28 28 28 17 Ankyrin repeat Ank_5 PF13857.6 ETS78896.1 - 4.5e-82 269.0 30.2 5.6e-06 26.5 0.0 22.7 9 5 15 25 25 25 21 Ankyrin repeats (many copies) Ank PF00023.30 ETS78896.1 - 1.4e-69 227.7 40.2 0.00066 20.0 0.0 25.7 27 0 0 27 27 27 15 Ankyrin repeat SPRY PF00622.28 ETS78896.1 - 7.8e-18 64.7 0.2 1.6e-17 63.7 0.2 1.5 1 0 0 1 1 1 1 SPRY domain DUF3447 PF11929.8 ETS78896.1 - 0.00023 21.0 0.1 23 5.0 0.2 5.1 4 1 0 4 4 4 0 Domain of unknown function (DUF3447) LuxQ-periplasm PF09308.10 ETS78896.1 - 0.041 13.4 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 LuxQ, periplasmic HET PF06985.11 ETS78899.1 - 6.7e-35 120.6 2.6 1.1e-34 119.9 2.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BASP1 PF05466.12 ETS78899.1 - 0.12 12.3 1.9 0.18 11.8 1.9 1.2 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) DAO PF01266.24 ETS78900.1 - 1.6e-29 103.6 0.0 2.4e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS78900.1 - 1.4e-05 25.2 0.3 0.0058 16.6 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 ETS78900.1 - 0.0012 18.0 0.0 0.0045 16.1 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ETS78900.1 - 0.0027 17.9 0.0 0.01 16.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 ETS78900.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 ETS78900.1 - 0.097 11.9 0.0 0.36 10.0 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ETS78900.1 - 0.1 11.4 0.0 2 7.2 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Het-C PF07217.11 ETS78900.1 - 0.17 10.4 0.0 0.25 9.8 0.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C UDPGT PF00201.18 ETS78901.1 - 1.1e-05 24.4 0.0 0.00026 19.9 0.0 2.0 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ETS78901.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Peptidase_S15 PF02129.18 ETS78903.1 - 1.8e-38 132.7 1.3 3.5e-36 125.2 1.3 2.2 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ETS78903.1 - 1.6e-37 129.7 0.0 2.2e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain PhyH PF05721.13 ETS78904.1 - 1.4e-07 32.0 0.1 6.1e-07 29.9 0.1 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 ETS78904.1 - 2e-06 26.8 0.7 0.012 14.4 0.1 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 ETS78904.1 - 0.076 13.4 0.0 0.23 11.9 0.0 1.8 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase MFS_1 PF07690.16 ETS78905.1 - 7.4e-19 67.9 19.8 7.4e-19 67.9 19.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS78905.1 - 1.8e-11 43.6 18.5 1e-10 41.1 18.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 ETS78905.1 - 0.0013 17.2 0.9 0.0021 16.6 0.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Tmemb_170 PF10190.9 ETS78905.1 - 0.008 16.5 0.6 0.008 16.5 0.6 3.4 3 1 1 4 4 4 1 Putative transmembrane protein 170 Cytochrom_B558a PF05038.13 ETS78905.1 - 0.083 12.5 0.3 0.18 11.3 0.3 1.5 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Steroid_dh PF02544.16 ETS78906.1 - 1.9e-27 96.1 0.3 2.7e-27 95.6 0.3 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 ETS78906.1 - 0.0055 16.2 0.3 0.0078 15.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 ETS78906.1 - 0.0058 17.0 0.1 0.011 16.1 0.1 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase GCN5L1 PF06320.13 ETS78907.1 - 3.4e-18 65.9 0.7 5.9e-18 65.1 0.7 1.4 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) eIF3_N PF09440.10 ETS78907.1 - 0.03 14.7 0.1 0.05 14.0 0.1 1.2 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain Rootletin PF15035.6 ETS78907.1 - 0.064 13.3 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SOG2 PF10428.9 ETS78908.1 - 5.4e-68 230.4 0.1 2e-44 152.7 0.3 4.9 4 1 1 5 5 5 2 RAM signalling pathway protein LRR_8 PF13855.6 ETS78908.1 - 3e-18 65.3 0.9 3.3e-09 36.4 0.0 2.8 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ETS78908.1 - 5.1e-15 55.3 9.8 1.2e-06 28.7 0.6 4.0 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ETS78908.1 - 0.011 16.2 3.9 16 6.5 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 ETS78908.1 - 0.76 10.0 11.4 3.3 8.0 0.2 5.2 6 0 0 6 6 6 0 Leucine Rich repeat DEAD PF00270.29 ETS78909.1 - 7.7e-17 61.6 0.0 1.5e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS78909.1 - 1.2e-15 57.8 0.0 1.6e-13 51.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 ETS78909.1 - 2.4e-11 44.2 2.4 5.4e-11 43.1 2.4 1.6 1 0 0 1 1 1 1 RecQ zinc-binding Peptidase_M16_C PF05193.21 ETS78909.1 - 0.12 12.3 0.0 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Peptidase M16 inactive domain CorA PF01544.18 ETS78910.1 - 3.8e-06 26.4 10.2 2e-05 24.1 10.2 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Ank_2 PF12796.7 ETS78911.1 - 8.7e-84 276.2 21.6 1.5e-14 54.4 0.0 8.6 2 2 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS78911.1 - 7.8e-57 189.0 4.7 1.9e-07 31.5 0.0 13.0 3 2 13 16 16 16 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS78911.1 - 1.3e-56 181.9 1.8 0.051 14.1 0.0 18.1 18 0 0 18 18 18 14 Ankyrin repeat Ank_5 PF13857.6 ETS78911.1 - 5.1e-56 186.0 10.3 7e-07 29.4 0.0 12.8 5 3 8 13 13 13 12 Ankyrin repeats (many copies) Ank PF00023.30 ETS78911.1 - 3.2e-55 182.3 5.3 0.043 14.3 0.0 17.8 17 1 0 17 17 17 13 Ankyrin repeat PNP_UDP_1 PF01048.20 ETS78911.1 - 2.7e-08 33.4 0.2 7.4e-08 31.9 0.2 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 ETS78911.1 - 1.7e-06 28.1 0.0 3.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Shigella_OspC PF06128.11 ETS78911.1 - 0.00029 20.7 5.3 9.4 5.9 0.1 5.8 3 1 1 7 7 7 1 Shigella flexneri OspC protein PEGA PF08308.11 ETS78911.1 - 0.0047 16.8 0.4 50 3.9 0.0 6.1 8 0 0 8 8 8 0 PEGA domain AAA_22 PF13401.6 ETS78911.1 - 0.0059 16.9 1.1 0.028 14.7 0.0 2.5 3 0 0 3 3 2 1 AAA domain DisA-linker PF10635.9 ETS78911.1 - 0.013 15.3 0.0 0.088 12.6 0.0 2.2 1 1 1 2 2 2 0 DisA bacterial checkpoint controller linker region AAA PF00004.29 ETS78911.1 - 0.062 13.7 0.0 0.28 11.6 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ThylakoidFormat PF11264.8 ETS78911.1 - 0.14 11.8 1.4 1.8 8.2 0.1 2.4 2 0 0 2 2 2 0 Thylakoid formation protein Pyr_redox_2 PF07992.14 ETS78912.1 - 1.8e-59 201.4 0.9 2.6e-59 200.9 0.9 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ETS78912.1 - 9.4e-33 112.8 0.2 1.9e-32 111.8 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ETS78912.1 - 1.4e-18 67.2 3.5 6.6e-18 65.0 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS78912.1 - 1.8e-18 66.9 0.1 2.3e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS78912.1 - 4.8e-05 22.2 1.8 0.94 8.1 0.0 3.2 3 0 0 3 3 3 3 HI0933-like protein K_oxygenase PF13434.6 ETS78912.1 - 5.5e-05 22.5 0.0 0.00018 20.8 0.0 1.8 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 ETS78912.1 - 0.006 15.8 0.3 0.012 14.8 0.3 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 ETS78912.1 - 0.016 14.6 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ETS78912.1 - 0.033 13.5 0.1 0.76 9.0 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 ETS78912.1 - 0.34 9.9 5.5 2.9 6.9 1.7 2.6 3 0 0 3 3 3 0 FAD binding domain DAO PF01266.24 ETS78912.1 - 0.35 10.4 2.1 1.8 8.0 1.2 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 ETS78912.1 - 1.4 7.9 5.4 4.5 6.2 5.2 2.0 2 1 0 2 2 2 0 Glucose inhibited division protein A Ydc2-catalyt PF09159.10 ETS78913.1 - 4.9e-66 223.3 0.0 7.1e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.27 ETS78913.1 - 0.00017 21.3 0.1 0.0004 20.1 0.1 1.7 1 0 0 1 1 1 1 SAP domain Pox_A22 PF04848.13 ETS78913.1 - 0.00039 20.5 0.0 0.92 9.6 0.0 3.0 3 0 0 3 3 3 2 Poxvirus A22 protein Pkinase PF00069.25 ETS78914.1 - 6.6e-69 232.2 0.0 1.7e-53 181.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS78914.1 - 2e-44 151.9 0.0 1.8e-36 125.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase MMR_HSR1 PF01926.23 ETS78914.1 - 4.4e-10 39.6 0.0 1.1e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Kinase-like PF14531.6 ETS78914.1 - 1.8e-05 24.2 0.0 0.00012 21.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ETS78914.1 - 3.2e-05 22.9 4.5 0.007 15.2 0.0 2.8 3 0 0 3 3 3 2 Fungal protein kinase AIG1 PF04548.16 ETS78914.1 - 0.00012 21.5 1.0 0.00019 20.8 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Kdo PF06293.14 ETS78914.1 - 0.00015 21.2 0.3 0.00039 19.8 0.3 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RsgA_GTPase PF03193.16 ETS78914.1 - 0.0004 20.3 0.0 0.00099 19.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 ETS78914.1 - 0.0034 17.5 0.5 0.0034 17.5 0.5 3.4 2 2 0 2 2 2 1 Dynamin family APH PF01636.23 ETS78914.1 - 0.033 14.1 2.4 0.083 12.8 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family IIGP PF05049.13 ETS78914.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Exonuc_VII_L PF02601.15 ETS78914.1 - 2.3 7.7 6.2 5.7 6.4 6.2 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 ETS78914.1 - 3.2 6.2 10.3 4.7 5.7 9.6 1.5 2 0 0 2 2 2 0 Flagellar Assembly Protein A GBP_C PF02841.14 ETS78914.1 - 5 6.4 17.0 10 5.4 17.0 1.5 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Vfa1 PF08432.10 ETS78914.1 - 7.5 6.8 11.5 18 5.6 11.5 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 HAUS6_N PF14661.6 ETS78914.1 - 8 6.0 10.2 16 5.0 10.2 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Pkinase_Tyr PF07714.17 ETS78915.1 - 8.9e-05 21.9 0.0 0.00059 19.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ETS78915.1 - 0.0013 18.1 0.0 0.0031 16.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain 3HCDH_N PF02737.18 ETS78916.1 - 2.2e-27 96.1 0.0 2.9e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ETS78916.1 - 6.4e-14 52.3 0.1 1.9e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ETS78916.1 - 0.0002 21.5 0.0 0.00045 20.4 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 ETS78916.1 - 0.04 13.9 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 ETS78916.1 - 0.047 13.0 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ETS78916.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_1 PF00175.21 ETS78917.1 - 7.5e-33 113.4 0.0 1.8e-32 112.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ETS78917.1 - 1e-30 106.0 0.0 2.2e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 ETS78917.1 - 3.1e-23 81.7 0.1 6.2e-23 80.7 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 ETS78917.1 - 3.3e-05 24.0 0.0 0.0014 18.8 0.0 2.8 3 0 0 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 ETS78917.1 - 0.16 12.2 0.0 0.7 10.1 0.0 2.1 1 1 0 1 1 1 0 Siderophore-interacting FAD-binding domain p450 PF00067.22 ETS78918.1 - 7e-73 245.9 0.0 8.6e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 ETS78919.1 - 1.1e-17 63.9 1.1 1.7e-17 63.3 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS78919.1 - 3.7e-05 23.8 9.4 0.0001 22.4 9.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sigma70_ner PF04546.13 ETS78919.1 - 0.074 12.9 1.1 0.13 12.1 1.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region FlxA PF14282.6 ETS78919.1 - 1.8 8.6 10.7 0.87 9.6 7.3 2.0 2 0 0 2 2 2 0 FlxA-like protein AIP3 PF03915.13 ETS78921.1 - 1.8e-159 531.2 9.1 1.8e-159 531.2 9.1 1.6 2 0 0 2 2 2 1 Actin interacting protein 3 Spore_III_AB PF09548.10 ETS78921.1 - 0.0017 18.5 2.2 0.0037 17.4 0.4 2.5 2 0 0 2 2 2 1 Stage III sporulation protein AB (spore_III_AB) Ribosomal_S13 PF00416.22 ETS78921.1 - 0.032 14.6 0.8 0.15 12.5 0.8 2.1 1 0 0 1 1 1 0 Ribosomal protein S13/S18 NPV_P10 PF05531.12 ETS78921.1 - 0.047 14.1 0.5 0.047 14.1 0.5 4.6 5 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein Lectin_N PF03954.14 ETS78921.1 - 0.05 13.3 7.1 0.06 13.1 1.1 3.5 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain Dict-STAT-coil PF09267.10 ETS78921.1 - 0.056 13.8 0.6 0.82 10.1 0.0 3.2 3 0 0 3 3 3 0 Dictyostelium STAT, coiled coil RasGAP_C PF03836.15 ETS78921.1 - 0.11 12.6 6.8 2 8.5 0.9 4.7 4 1 1 5 5 5 0 RasGAP C-terminus FliL PF03748.14 ETS78921.1 - 0.14 12.8 1.1 1.1 9.8 0.1 3.0 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL GNVR PF13807.6 ETS78921.1 - 0.36 10.8 1.7 0.63 10.0 0.3 2.0 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase DUF1664 PF07889.12 ETS78921.1 - 0.44 10.6 11.3 1.3 9.0 0.2 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) WXG100 PF06013.12 ETS78921.1 - 0.75 10.1 10.1 51 4.2 0.0 5.7 4 1 1 5 5 5 0 Proteins of 100 residues with WXG TraF_2 PF13729.6 ETS78921.1 - 1.8 7.9 5.3 1.8 7.9 0.1 2.9 3 0 0 3 3 3 0 F plasmid transfer operon, TraF, protein IL11 PF07400.11 ETS78921.1 - 2.5 7.7 7.1 14 5.3 0.1 4.3 4 0 0 4 4 4 0 Interleukin 11 YtxH PF12732.7 ETS78921.1 - 3.4 8.3 6.5 8.8 6.9 0.0 3.9 3 1 0 3 3 3 0 YtxH-like protein CdvA PF18822.1 ETS78921.1 - 5.3 6.9 12.6 0.37 10.6 0.2 4.2 4 0 0 4 4 4 0 CdvA-like coiled-coil domain Baculo_PEP_C PF04513.12 ETS78921.1 - 10 6.2 10.9 9.5 6.3 0.1 4.4 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAD_binding_3 PF01494.19 ETS78922.1 - 4.1e-16 59.2 0.0 3.8e-15 56.0 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS78922.1 - 3.1e-06 27.0 0.3 0.071 12.7 0.0 2.9 1 1 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 ETS78922.1 - 0.00085 18.4 0.0 0.0017 17.5 0.0 1.4 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.12 ETS78922.1 - 0.00088 18.4 0.0 0.34 9.9 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.27 ETS78922.1 - 0.046 14.3 0.0 0.13 12.9 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase S_100 PF01023.19 ETS78922.1 - 0.16 11.7 0.6 0.44 10.3 0.6 1.7 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Thi4 PF01946.17 ETS78922.1 - 0.22 10.7 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family LsmAD PF06741.13 ETS78923.1 - 5.1e-27 94.2 1.3 5.1e-27 94.2 1.3 2.4 2 0 0 2 2 2 1 LsmAD domain LPMO_10 PF03067.15 ETS78924.1 - 0.0017 19.0 0.1 0.0048 17.6 0.1 1.8 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Cupin_2 PF07883.11 ETS78925.1 - 1.5e-16 59.9 0.1 2.7e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ETS78925.1 - 0.00012 21.7 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 ETS78925.1 - 0.00019 21.3 0.0 0.00029 20.8 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.7 ETS78925.1 - 0.00047 19.9 0.0 0.00052 19.8 0.0 1.3 1 0 0 1 1 1 1 Cupin ARD PF03079.14 ETS78925.1 - 0.00066 19.9 0.2 0.0014 18.8 0.0 1.6 2 0 0 2 2 2 1 ARD/ARD' family Cupin_3 PF05899.12 ETS78925.1 - 0.0014 18.3 0.1 0.0026 17.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) JmjC PF02373.22 ETS78925.1 - 0.066 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase EF-hand_4 PF12763.7 ETS78927.1 - 2.4e-33 114.2 0.0 1.5e-11 44.1 0.0 3.9 4 0 0 4 4 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 ETS78927.1 - 4.4e-09 36.7 0.0 0.0017 18.8 0.0 4.6 4 0 0 4 4 4 1 EF-hand domain pair UBA PF00627.31 ETS78927.1 - 2.5e-06 27.3 0.1 5.7e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 ETS78927.1 - 5e-06 25.7 0.0 4.7 7.0 0.1 5.5 6 0 0 6 6 6 0 EF hand EF-hand_6 PF13405.6 ETS78927.1 - 5.5e-05 22.8 0.1 1.3 9.2 0.1 5.1 5 0 0 5 5 4 1 EF-hand domain Macoilin PF09726.9 ETS78927.1 - 0.001 17.8 17.7 0.0018 17.0 17.7 1.3 1 0 0 1 1 1 1 Macoilin family GAS PF13851.6 ETS78927.1 - 0.0039 16.6 33.7 0.016 14.6 14.7 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 ETS78927.1 - 0.004 16.1 35.3 0.21 10.4 13.7 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein AIP3 PF03915.13 ETS78927.1 - 0.013 14.6 24.6 0.019 14.0 24.6 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 PRKG1_interact PF15898.5 ETS78927.1 - 0.014 16.3 18.6 0.014 16.3 18.6 3.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF3584 PF12128.8 ETS78927.1 - 0.014 12.9 32.9 0.02 12.5 32.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ATG16 PF08614.11 ETS78927.1 - 0.024 14.8 38.6 0.04 14.2 25.5 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FUSC PF04632.12 ETS78927.1 - 0.11 11.0 9.8 0.18 10.3 9.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fez1 PF06818.15 ETS78927.1 - 0.18 12.2 30.8 0.053 14.0 18.0 2.2 1 1 1 2 2 2 0 Fez1 TolA_bind_tri PF16331.5 ETS78927.1 - 0.23 11.6 36.7 0.5 10.5 9.3 4.7 2 1 3 5 5 5 0 TolA binding protein trimerisation Lebercilin PF15619.6 ETS78927.1 - 0.25 11.0 35.4 0.46 10.1 35.4 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Golgin_A5 PF09787.9 ETS78927.1 - 0.31 10.5 34.1 0.063 12.7 25.9 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF1664 PF07889.12 ETS78927.1 - 0.32 11.0 20.8 0.33 11.0 8.5 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 ETS78927.1 - 0.32 11.5 37.3 0.34 11.4 22.0 3.2 1 1 2 3 3 3 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 ETS78927.1 - 0.35 10.9 40.3 6.3 6.9 23.6 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 ETS78927.1 - 0.39 11.0 31.1 1.5 9.0 4.1 3.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 ETS78927.1 - 0.53 10.3 34.2 0.042 13.9 12.1 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 ETS78927.1 - 0.7 9.4 32.2 0.093 12.3 13.5 2.2 1 1 1 2 2 2 0 Intermediate filament protein DUF4201 PF13870.6 ETS78927.1 - 0.78 9.4 29.9 8.2 6.1 7.4 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) FapA PF03961.13 ETS78927.1 - 1.4 7.5 24.9 1.9 7.0 9.7 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A ADIP PF11559.8 ETS78927.1 - 1.9 8.6 37.4 3.5 7.7 14.9 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Taxilin PF09728.9 ETS78927.1 - 2.3 7.3 36.0 0.28 10.3 31.8 1.4 2 0 0 2 2 2 0 Myosin-like coiled-coil protein IFT57 PF10498.9 ETS78927.1 - 3.1 6.7 27.7 2.4 7.0 20.3 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 HAP1_N PF04849.13 ETS78927.1 - 3.7 6.7 31.0 0.83 8.8 20.5 2.4 1 1 0 2 2 2 0 HAP1 N-terminal conserved region DUF2353 PF09789.9 ETS78927.1 - 3.7 6.8 27.2 2.4 7.5 0.4 2.0 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF3450 PF11932.8 ETS78927.1 - 3.9 6.7 36.8 1.3 8.2 15.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 ETS78927.1 - 5.2 6.3 30.6 3.7 6.8 16.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 ETS78927.1 - 5.6 7.2 30.1 4.4 7.6 11.2 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HemX PF04375.14 ETS78927.1 - 6 6.0 36.5 3.9 6.7 15.6 2.2 1 1 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Cluap1 PF10234.9 ETS78927.1 - 6.7 6.0 25.7 9.3 5.6 24.6 1.7 1 1 0 1 1 1 0 Clusterin-associated protein-1 DUF724 PF05266.14 ETS78927.1 - 7.2 6.4 27.2 0.26 11.1 10.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF724) kleA_kleC PF17383.2 ETS78927.1 - 7.4 7.0 8.7 3 8.2 1.3 3.4 1 1 1 3 3 3 0 Uncharacterized KorC regulated protein A HMMR_N PF15905.5 ETS78927.1 - 7.7 5.9 31.0 16 4.8 31.0 1.5 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF2730 PF10805.8 ETS78927.1 - 8 6.6 20.2 8.3 6.6 1.1 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) COG2 PF06148.11 ETS78927.1 - 9.2 6.4 17.7 2.7 8.1 5.1 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tubulin PF00091.25 ETS78928.1 - 4.1e-67 226.2 0.0 5.6e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ETS78928.1 - 3.6e-49 166.1 0.0 6e-49 165.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 ETS78928.1 - 0.0025 17.5 0.0 0.0063 16.2 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain Pga1 PF10333.9 ETS78929.1 - 5.3e-06 26.4 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator WW PF00397.26 ETS78930.1 - 4.3e-10 39.5 1.0 1.2e-09 38.1 1.0 1.8 1 0 0 1 1 1 1 WW domain Glyco_hydro_127 PF07944.12 ETS78932.1 - 1.8e-17 63.1 0.5 3e-14 52.4 0.1 2.1 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 ETS78932.1 - 4.5e-05 22.7 0.1 0.00083 18.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Transferase PF02458.15 ETS78933.1 - 1.2e-28 99.9 0.0 9.6e-28 97.0 0.0 2.2 1 1 0 1 1 1 1 Transferase family DUF3973 PF13119.6 ETS78935.1 - 0.024 14.7 0.7 0.066 13.3 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) Myb_DNA-binding PF00249.31 ETS78936.1 - 7.5e-06 26.0 0.0 1.9e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C2H2_4 PF13894.6 ETS78936.1 - 0.0016 19.1 20.0 0.044 14.6 0.3 4.9 4 0 0 4 4 4 2 C2H2-type zinc finger Myb_DNA-bind_7 PF15963.5 ETS78936.1 - 0.0058 16.5 0.5 0.039 13.8 0.2 2.5 2 0 0 2 2 2 1 Myb DNA-binding like DUF629 PF04780.12 ETS78936.1 - 0.013 14.0 6.7 0.2 10.1 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF629) HTH_50 PF18024.1 ETS78936.1 - 0.2 11.3 0.4 0.86 9.3 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain zf-Di19 PF05605.12 ETS78936.1 - 0.41 11.0 17.8 2.2 8.6 1.7 4.1 2 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 ETS78936.1 - 2.9 8.3 8.3 2 8.8 1.7 3.3 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Fringe PF02434.16 ETS78937.1 - 3.7e-05 23.3 0.2 0.00067 19.2 0.2 2.1 1 1 0 1 1 1 1 Fringe-like IGFL PF14653.6 ETS78937.1 - 0.018 15.0 0.3 0.039 13.9 0.3 1.5 1 0 0 1 1 1 0 Insulin growth factor-like family Galactosyl_T PF01762.21 ETS78937.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.5 1 1 0 1 1 1 0 Galactosyltransferase PAN_3 PF08277.12 ETS78937.1 - 0.089 12.6 1.6 0.19 11.5 1.6 1.5 1 0 0 1 1 1 0 PAN-like domain PAN_4 PF14295.6 ETS78937.1 - 0.11 12.4 1.9 0.28 11.1 1.9 1.6 1 0 0 1 1 1 0 PAN domain Toxin_17 PF08086.11 ETS78937.1 - 8.1 6.8 7.7 16 5.9 4.6 2.4 2 0 0 2 2 2 0 Ergtoxin family zf-TRAF PF02176.18 ETS78938.1 - 4.3e-17 62.6 22.9 2.6e-06 28.0 1.7 3.7 1 1 2 3 3 3 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 ETS78938.1 - 6.1e-07 29.2 7.0 6.1e-07 29.2 7.0 3.8 2 1 2 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS78938.1 - 8.5e-07 28.7 4.4 8.5e-07 28.7 4.4 3.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 ETS78938.1 - 8.6e-07 29.3 20.8 1.7e-05 25.2 5.1 2.6 2 0 0 2 2 2 2 TRAF-like zinc-finger zf-RING_5 PF14634.6 ETS78938.1 - 7e-06 25.9 5.7 7e-06 25.9 5.7 3.5 2 2 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ETS78938.1 - 1.4e-05 25.0 4.6 1.4e-05 25.0 4.6 2.9 2 1 0 2 2 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 ETS78938.1 - 4.8e-05 23.6 6.4 4.8e-05 23.6 6.4 3.7 3 1 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 ETS78938.1 - 7.6e-05 22.5 6.1 7.6e-05 22.5 6.1 4.1 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ETS78938.1 - 7.9e-05 22.7 6.4 7.9e-05 22.7 6.4 2.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ETS78938.1 - 0.0041 17.0 6.9 0.0041 17.0 6.9 3.2 2 2 2 4 4 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 ETS78938.1 - 0.005 17.0 4.5 0.005 17.0 4.5 2.7 2 0 0 2 2 2 1 zinc RING finger of MSL2 TRAF6_Z2 PF18048.1 ETS78938.1 - 0.26 11.4 7.6 9 6.5 0.2 3.3 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 IBR PF01485.21 ETS78938.1 - 1.9 8.8 26.6 1.5 9.1 0.6 4.3 2 1 2 4 4 4 0 IBR domain, a half RING-finger domain zf-RING_6 PF14835.6 ETS78938.1 - 2.4 8.1 7.9 0.14 12.1 2.2 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Sina PF03145.16 ETS78938.1 - 9.5 6.1 17.0 2.7 7.9 0.4 3.2 1 1 1 3 3 3 0 Seven in absentia protein family AAA PF00004.29 ETS78939.1 - 4.8e-16 59.4 0.0 1.1e-15 58.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS78939.1 - 0.0031 17.9 0.0 0.0078 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ETS78939.1 - 0.0071 16.4 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 ETS78939.1 - 0.01 15.8 0.0 0.039 13.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 ETS78939.1 - 0.077 12.3 1.4 0.76 9.1 0.5 2.5 1 1 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 ETS78939.1 - 0.084 12.6 0.0 0.96 9.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.6 ETS78939.1 - 0.15 12.3 0.1 0.81 10.0 0.0 2.1 1 1 1 2 2 2 0 AAA domain Bromodomain PF00439.25 ETS78941.1 - 2.7e-06 27.4 0.0 9e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 Bromodomain DHR10 PF18595.1 ETS78942.1 - 0.00044 20.3 2.0 0.00066 19.7 2.0 1.2 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain SlyX PF04102.12 ETS78942.1 - 0.00056 20.5 1.5 0.0011 19.5 1.5 1.5 1 0 0 1 1 1 1 SlyX Filament PF00038.21 ETS78942.1 - 0.00058 19.5 0.8 0.00072 19.2 0.8 1.1 1 0 0 1 1 1 1 Intermediate filament protein Tropomyosin PF00261.20 ETS78942.1 - 0.003 16.9 2.1 0.0043 16.5 2.1 1.1 1 0 0 1 1 1 1 Tropomyosin HrpB7 PF09486.10 ETS78942.1 - 0.0078 16.6 0.9 0.012 16.0 0.9 1.3 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) XhlA PF10779.9 ETS78942.1 - 0.008 16.4 3.6 0.015 15.5 3.6 1.4 1 0 0 1 1 1 1 Haemolysin XhlA Cob_adeno_trans PF01923.18 ETS78942.1 - 0.011 15.9 0.1 0.015 15.4 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Spc7 PF08317.11 ETS78942.1 - 0.011 14.6 0.5 0.013 14.5 0.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF16 PF01519.16 ETS78942.1 - 0.03 14.8 0.5 0.045 14.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Csm1_N PF18504.1 ETS78942.1 - 0.037 14.4 1.5 0.067 13.5 1.5 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain ABC_tran_CTD PF16326.5 ETS78942.1 - 0.048 13.9 1.1 0.09 13.0 1.1 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain COG2 PF06148.11 ETS78942.1 - 0.052 13.6 0.3 0.073 13.2 0.3 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc24 PF08286.11 ETS78942.1 - 0.087 13.1 1.4 0.14 12.4 1.4 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF724 PF05266.14 ETS78942.1 - 0.1 12.4 1.6 0.15 11.9 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ABC_tran_Xtn PF12848.7 ETS78942.1 - 0.14 12.2 1.7 0.2 11.7 1.7 1.3 1 0 0 1 1 1 0 ABC transporter DUF2098 PF09871.9 ETS78942.1 - 0.16 12.3 0.6 0.27 11.6 0.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) DivIC PF04977.15 ETS78942.1 - 0.16 11.7 1.2 0.32 10.8 1.2 1.5 1 0 0 1 1 1 0 Septum formation initiator Sugarporin_N PF11471.8 ETS78942.1 - 0.28 11.2 3.3 0.51 10.3 3.3 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension ATG16 PF08614.11 ETS78942.1 - 0.29 11.3 8.1 0.23 11.7 7.1 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Asp PF00026.23 ETS78943.1 - 4.8e-52 177.3 0.4 5.7e-52 177.1 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS78943.1 - 1.1e-11 45.3 0.4 4.5e-05 23.8 0.0 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal HSP70 PF00012.20 ETS78944.1 - 6.4e-60 203.0 14.2 2.7e-58 197.6 12.2 2.9 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ETS78944.1 - 2e-05 23.6 0.1 0.00067 18.6 0.0 2.4 2 0 0 2 2 2 1 MreB/Mbl protein DUF2294 PF10057.9 ETS78944.1 - 0.00081 19.5 0.4 0.0032 17.6 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2294) DivIVA PF05103.13 ETS78944.1 - 0.019 15.1 0.9 0.019 15.1 0.9 2.6 3 0 0 3 3 3 0 DivIVA protein FGGY_C PF02782.16 ETS78944.1 - 0.05 13.3 0.3 0.36 10.5 0.1 2.5 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Cyt-b5 PF00173.28 ETS78946.1 - 7.4e-12 45.2 0.0 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cu_bind_like PF02298.17 ETS78947.1 - 0.001 19.0 0.0 0.0022 18.0 0.0 1.5 1 1 0 1 1 1 1 Plastocyanin-like domain Cupredoxin_1 PF13473.6 ETS78947.1 - 0.0045 17.1 0.0 0.0092 16.1 0.0 1.5 1 0 0 1 1 1 1 Cupredoxin-like domain Copper-bind PF00127.20 ETS78947.1 - 0.051 14.0 2.6 0.085 13.3 0.4 2.3 2 1 0 2 2 2 0 Copper binding proteins, plastocyanin/azurin family RAP1 PF07218.11 ETS78947.1 - 7.2 4.7 7.6 8 4.6 7.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CENP-X PF09415.10 ETS78948.1 - 1.7e-24 85.9 0.5 1.7e-24 85.9 0.5 1.9 2 0 0 2 2 2 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 ETS78948.1 - 0.0092 16.2 0.1 0.017 15.4 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TRAP_alpha PF03896.16 ETS78948.1 - 0.45 9.7 2.7 0.55 9.4 2.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Mito_carr PF00153.27 ETS78949.1 - 6e-65 215.2 4.7 7.1e-23 80.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 ETS78949.1 - 0.015 15.0 1.1 0.048 13.4 1.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Ribosomal_S25 PF03297.15 ETS78950.1 - 6.9e-38 128.9 7.0 7.5e-38 128.8 7.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein RNA_pol_Rpc34 PF05158.12 ETS78950.1 - 0.001 18.5 1.0 0.0013 18.1 0.3 1.4 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_24 PF13412.6 ETS78950.1 - 0.011 15.3 0.1 0.016 14.7 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.20 ETS78950.1 - 0.018 15.4 0.1 0.027 14.8 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.7 ETS78950.1 - 0.048 13.6 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 MarR family TrmB PF01978.19 ETS78950.1 - 0.066 13.1 0.4 0.089 12.7 0.4 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_11 PF08279.12 ETS78950.1 - 0.078 12.9 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 HTH domain HTH_DeoR PF08220.12 ETS78950.1 - 0.079 12.7 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Ribosomal_S7 PF00177.21 ETS78951.1 - 1.1e-37 128.9 1.5 1.4e-37 128.6 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Acetyltransf_10 PF13673.7 ETS78952.1 - 0.00026 20.9 0.0 0.92 9.5 0.0 2.5 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS78952.1 - 0.0016 18.6 0.0 0.0045 17.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 ETS78952.1 - 0.0073 17.0 0.1 0.22 12.3 0.1 2.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain SET PF00856.28 ETS78954.1 - 0.0063 16.9 0.2 0.26 11.7 0.0 2.3 2 0 0 2 2 2 2 SET domain DcpS_C PF11969.8 ETS78956.1 - 1.3e-06 28.9 0.1 0.00062 20.2 0.1 2.4 1 1 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 ETS78956.1 - 0.016 15.9 0.0 0.073 13.8 0.0 2.2 2 0 0 2 2 2 0 HIT domain Phage_GP20 PF06810.11 ETS78957.1 - 0.33 10.7 5.5 0.32 10.8 3.7 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 Ribosomal_L26 PF16906.5 ETS78958.1 - 7.2e-39 132.1 2.0 9.9e-39 131.7 2.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 ETS78958.1 - 3.1e-07 30.1 1.6 3.1e-07 30.1 1.6 1.7 2 0 0 2 2 2 1 KOW motif DUF1223 PF06764.11 ETS78958.1 - 0.14 12.2 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) Methyltransf_23 PF13489.6 ETS78960.1 - 1.1e-15 57.8 0.0 1.4e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS78960.1 - 3.3e-13 50.2 0.0 7.6e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS78960.1 - 4.3e-11 42.8 0.0 3.4e-10 39.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS78960.1 - 1.4e-10 41.7 0.0 8.5e-10 39.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS78960.1 - 1e-08 35.7 0.0 2.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS78960.1 - 0.00031 20.3 0.0 0.0025 17.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 ETS78960.1 - 0.00038 20.0 0.0 0.0012 18.3 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 ETS78960.1 - 0.00085 18.7 0.0 0.0079 15.6 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 ETS78960.1 - 0.0012 19.0 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 ETS78960.1 - 0.021 14.1 0.0 0.06 12.6 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 ETS78960.1 - 0.052 13.3 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_15 PF09445.10 ETS78960.1 - 0.054 13.1 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 ETS78960.1 - 0.17 11.2 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 ETS78960.1 - 0.19 11.5 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase PCMT PF01135.19 ETS78960.1 - 0.2 11.4 0.0 0.56 9.9 0.0 1.8 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cyt-b5 PF00173.28 ETS78961.1 - 1.5e-18 66.7 0.7 4.8e-18 65.1 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 ETS78961.1 - 6e-13 49.3 19.1 6e-13 49.3 19.1 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 ETS78961.1 - 0.0075 16.5 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region ATP-synt_I PF03899.15 ETS78961.1 - 0.11 12.9 3.1 6.2 7.3 0.4 2.2 2 0 0 2 2 2 0 ATP synthase I chain DUF1453 PF07301.11 ETS78961.1 - 0.38 10.8 2.3 0.57 10.2 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1453) Ima1_N PF09779.9 ETS78962.1 - 6.1e-31 108.1 0.9 1e-30 107.3 0.9 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.7 ETS78962.1 - 0.41 10.7 2.4 4.1 7.5 0.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon PyrI_C PF02748.15 ETS78962.1 - 2.3 8.2 4.5 23 5.0 0.1 2.4 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Alg14 PF08660.11 ETS78963.1 - 2.2e-43 148.2 0.0 4.8e-43 147.1 0.0 1.5 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like AcMNPV_Ac109 PF05054.12 ETS78963.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein MRP-S25 PF13741.6 ETS78964.1 - 8.5e-63 212.0 8.5 1.1e-60 205.1 8.5 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 ETS78964.1 - 2.2e-05 24.7 3.7 2.2e-05 24.7 3.7 2.1 2 1 0 2 2 2 1 Mitochondrial ribosomal protein S23 PPR_2 PF13041.6 ETS78965.1 - 3.3e-14 52.8 0.0 0.0029 17.8 0.0 4.7 3 1 1 4 4 4 4 PPR repeat family PPR PF01535.20 ETS78965.1 - 6.7e-09 35.4 7.5 0.0035 17.5 0.0 5.6 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.7 ETS78965.1 - 0.012 15.3 3.9 1.8 8.3 0.0 4.0 4 1 0 4 4 4 0 PPR repeat PPR_3 PF13812.6 ETS78965.1 - 0.016 15.3 0.1 2.6 8.2 0.0 3.5 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PPR_long PF17177.4 ETS78965.1 - 0.033 13.5 0.1 0.099 12.0 0.1 1.8 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP Clr5 PF14420.6 ETS78966.1 - 4.2e-19 68.5 3.6 1.1e-18 67.2 3.6 1.8 1 0 0 1 1 1 1 Clr5 domain COX7C PF02935.16 ETS78967.1 - 1.5e-24 86.0 3.0 1.7e-24 85.8 3.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.6 ETS78968.1 - 8e-87 291.6 0.1 3.1e-86 289.7 0.0 2.1 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 ETS78968.1 - 1.8e-49 167.6 3.3 4.1e-49 166.4 2.7 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 ETS78968.1 - 5.1e-20 72.0 1.5 3.9e-19 69.1 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS78968.1 - 7.7e-08 32.7 0.1 6.7e-07 29.6 0.1 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS78968.1 - 2.8e-06 27.5 0.1 3.9e-05 23.7 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 ETS78968.1 - 0.019 14.0 0.0 0.12 11.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein HTH_11 PF08279.12 ETS78968.1 - 0.036 14.0 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 HTH domain AAA_22 PF13401.6 ETS78968.1 - 0.11 12.7 0.0 0.74 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain RecX PF02631.16 ETS78968.1 - 0.13 12.8 1.9 1.9 9.0 0.2 3.0 2 0 0 2 2 2 0 RecX family ATPase_2 PF01637.18 ETS78968.1 - 0.22 11.4 0.0 0.22 11.4 0.0 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Aminotran_1_2 PF00155.21 ETS78969.1 - 4.2e-72 243.3 0.0 4.9e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ETS78969.1 - 0.00028 20.3 0.0 0.00043 19.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ETS78969.1 - 0.0012 18.2 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 ETS78969.1 - 0.003 16.2 0.0 0.0056 15.3 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ETS78969.1 - 0.0046 16.0 0.0 0.01 14.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V FAD_binding_9 PF08021.11 ETS78969.1 - 0.14 12.4 0.0 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain DUF2407_C PF13373.6 ETS78970.1 - 7.9e-36 123.3 0.0 1e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 ETS78970.1 - 1.2e-29 102.9 0.0 1.8e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Epimerase PF01370.21 ETS78971.1 - 4.2e-16 59.1 0.0 8.3e-16 58.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS78971.1 - 1e-09 37.8 0.0 5.4e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ETS78971.1 - 1.7e-09 37.2 0.0 2.6e-08 33.3 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 ETS78971.1 - 3.4e-07 30.3 0.2 1.1e-06 28.6 0.0 2.1 3 0 0 3 3 3 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ETS78971.1 - 1.8e-05 24.3 0.0 3.5e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ETS78971.1 - 0.00042 20.0 0.0 0.0016 18.0 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 ETS78971.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.17 ETS78971.1 - 0.013 14.6 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 ETS78971.1 - 0.062 12.8 0.0 0.24 10.8 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase Ald_Xan_dh_C2 PF02738.18 ETS78972.1 - 7.2e-210 698.1 0.0 1e-209 697.6 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 ETS78972.1 - 4.6e-47 159.9 0.0 9.5e-47 158.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 ETS78972.1 - 2.2e-32 111.3 0.1 7.7e-32 109.5 0.1 2.0 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 ETS78972.1 - 1.6e-30 104.9 0.0 3.3e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 ETS78972.1 - 8.3e-28 96.9 0.0 1.9e-27 95.8 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.27 ETS78972.1 - 1.2e-07 31.5 1.7 2e-07 30.8 0.1 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 ETS78972.1 - 0.062 13.3 0.0 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 DUF218 domain Transferase PF02458.15 ETS78973.1 - 1.3e-27 96.6 0.0 3.5e-10 39.1 0.0 3.1 3 0 0 3 3 3 3 Transferase family NmrA PF05368.13 ETS78974.1 - 4.5e-12 46.0 0.0 6.8e-12 45.4 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS78974.1 - 4e-10 39.9 0.0 2.1e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding Semialdhyde_dh PF01118.24 ETS78974.1 - 0.014 15.8 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain FMN_dh PF01070.18 ETS78975.1 - 1e-113 379.9 0.0 1.2e-113 379.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 ETS78975.1 - 0.0012 18.4 0.4 0.0017 17.8 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ETS78975.1 - 0.0021 17.1 0.5 0.0038 16.3 0.1 1.5 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ETS78975.1 - 0.0024 17.1 0.1 0.0036 16.5 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 ETS78975.1 - 0.0085 15.6 0.2 0.5 9.8 0.0 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 ETS78975.1 - 0.022 14.1 0.2 0.97 8.7 0.0 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Med18 PF09637.10 ETS78976.1 - 3.8e-27 95.7 0.0 4.5e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Med18 protein zf-C2H2 PF00096.26 ETS78977.1 - 0.041 14.4 0.8 0.041 14.4 0.8 5.5 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ETS78977.1 - 0.072 13.6 0.4 0.072 13.6 0.4 3.4 5 0 0 5 5 5 0 Zinc-finger double domain zf-CHCC PF10276.9 ETS78977.1 - 0.13 12.4 2.4 7 6.8 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger domain DSPc PF00782.20 ETS78978.1 - 5.3e-15 55.4 0.1 3.3e-06 27.0 0.2 3.2 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 ETS78978.1 - 0.047 14.0 0.0 0.092 13.0 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain zinc_ribbon_5 PF13719.6 ETS78978.1 - 0.12 12.1 4.0 0.2 11.5 0.6 2.7 3 0 0 3 3 3 0 zinc-ribbon domain EGF_3 PF12947.7 ETS78978.1 - 1.3 9.3 4.0 0.46 10.7 0.7 2.0 2 0 0 2 2 2 0 EGF domain Vfa1 PF08432.10 ETS78979.1 - 2.9e-41 141.8 16.5 3.2e-41 141.7 16.5 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 ETS78979.1 - 0.036 12.4 12.8 0.037 12.3 12.8 1.0 1 0 0 1 1 1 0 CDC45-like protein SID-1_RNA_chan PF13965.6 ETS78979.1 - 0.076 11.4 0.7 0.093 11.1 0.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RNA_pol_Rpc4 PF05132.14 ETS78979.1 - 0.078 13.4 8.5 0.097 13.1 8.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Pet100 PF09803.9 ETS78979.1 - 0.087 13.4 1.0 0.087 13.4 1.0 1.7 2 0 0 2 2 1 0 Pet100 T2SSF PF00482.23 ETS78979.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF5427 PF10310.9 ETS78979.1 - 0.13 11.2 14.7 0.15 11.0 14.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF908 PF06012.12 ETS78979.1 - 0.17 11.3 3.8 0.16 11.3 3.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SLC12 PF03522.15 ETS78979.1 - 0.22 10.5 6.3 0.25 10.3 6.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 ETS78979.1 - 0.31 10.8 15.9 0.37 10.6 15.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 ETS78979.1 - 0.32 9.9 5.5 0.31 10.0 5.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Peptidase_S49_N PF08496.10 ETS78979.1 - 0.35 10.9 12.3 0.49 10.5 12.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Afi1 PF07792.12 ETS78979.1 - 0.43 11.1 11.5 0.55 10.7 11.5 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SAPS PF04499.15 ETS78979.1 - 0.71 8.6 9.0 0.75 8.5 9.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2052 PF09747.9 ETS78979.1 - 0.75 9.9 17.3 0.95 9.6 17.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) NOA36 PF06524.12 ETS78979.1 - 0.97 8.7 13.8 1.2 8.4 13.8 1.1 1 0 0 1 1 1 0 NOA36 protein DUF3438 PF11920.8 ETS78979.1 - 1.4 8.1 10.2 1.8 7.8 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) PIEZO PF15917.5 ETS78979.1 - 1.8 8.0 11.7 2.1 7.8 11.7 1.1 1 0 0 1 1 1 0 Piezo Serinc PF03348.15 ETS78979.1 - 3.1 6.6 3.3 3 6.7 3.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FAM60A PF15396.6 ETS78979.1 - 3.1 7.8 15.4 5.6 6.9 12.7 1.9 2 0 0 2 2 2 0 Protein Family FAM60A Presenilin PF01080.17 ETS78979.1 - 3.3 6.4 11.6 4 6.1 11.6 1.0 1 0 0 1 1 1 0 Presenilin RP-C_C PF11800.8 ETS78979.1 - 5.7 7.0 7.2 6.8 6.7 7.2 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Sporozoite_P67 PF05642.11 ETS78979.1 - 6.3 4.8 13.3 7.6 4.5 13.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hid1 PF12722.7 ETS78979.1 - 6.6 4.7 7.6 7.3 4.6 7.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 ETS78979.1 - 8 5.6 8.7 10 5.3 8.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3987 PF13148.6 ETS78979.1 - 9.1 5.2 7.7 11 4.9 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Rtt106 PF08512.12 ETS78980.1 - 7.6e-30 103.2 0.0 6.7e-29 100.2 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 ETS78980.1 - 0.00039 20.4 0.0 0.0022 18.0 0.0 2.2 3 1 0 3 3 3 1 Pleckstrin homology domain TFIIA PF03153.13 ETS78980.1 - 5 7.0 19.2 9 6.2 19.2 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PH_10 PF15411.6 ETS78983.1 - 2.2e-42 144.2 0.4 3.7e-42 143.5 0.4 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 ETS78983.1 - 1.3e-28 100.5 0.5 2.2e-28 99.7 0.0 1.6 2 0 0 2 2 2 1 RhoGEF domain CDC24 PF06395.11 ETS78983.1 - 6.5e-25 87.2 0.0 1.4e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.24 ETS78983.1 - 6.7e-09 35.6 0.0 1.7e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 ETS78983.1 - 0.088 13.3 1.2 0.24 11.9 0.5 2.0 2 1 0 2 2 2 0 PH domain WD40 PF00400.32 ETS78984.1 - 1.3e-27 95.5 19.0 3.8e-06 27.5 0.4 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 ETS78984.1 - 3.6e-12 46.0 1.0 3.6e-12 46.0 1.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ETS78984.1 - 2e-06 27.5 0.2 5.2e-06 26.2 0.2 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 ETS78984.1 - 0.00019 21.7 0.0 7.6 6.9 0.0 3.6 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 ETS78984.1 - 0.036 13.9 0.2 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 F-box PALB2_WD40 PF16756.5 ETS78984.1 - 0.13 11.2 0.2 17 4.2 0.0 3.0 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Snf7 PF03357.21 ETS78985.1 - 2.2e-44 151.1 13.5 2.6e-44 150.9 13.5 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 ETS78985.1 - 0.0019 18.6 0.7 0.22 12.0 0.7 2.7 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Sec34 PF04136.15 ETS78985.1 - 0.012 15.5 1.3 0.5 10.2 0.4 2.2 1 1 1 2 2 2 0 Sec34-like family OmpH PF03938.14 ETS78985.1 - 0.18 12.2 17.6 0.29 11.5 6.7 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DASH_Dam1 PF08653.10 ETS78985.1 - 0.33 10.8 2.1 18 5.2 0.1 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 TMPIT PF07851.13 ETS78985.1 - 0.42 9.8 2.9 0.55 9.4 2.9 1.3 1 0 0 1 1 1 0 TMPIT-like protein Mod_r PF07200.13 ETS78985.1 - 0.53 10.4 9.7 0.79 9.8 9.1 1.5 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF2120 PF09893.9 ETS78985.1 - 0.59 10.2 4.9 0.51 10.4 3.5 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) FTCD_C PF04961.12 ETS78985.1 - 0.7 9.6 5.7 2 8.2 5.7 1.9 1 1 0 1 1 1 0 Formiminotransferase-cyclodeaminase Muted PF14942.6 ETS78985.1 - 0.73 10.2 10.0 4.1 7.7 9.9 2.0 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein LMBR1 PF04791.16 ETS78985.1 - 1.4 7.8 3.2 1.6 7.5 3.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2205 PF10224.9 ETS78985.1 - 3.3 7.8 10.6 0.51 10.4 2.7 2.6 2 1 1 3 3 3 0 Short coiled-coil protein Cep57_MT_bd PF06657.13 ETS78985.1 - 5.4 7.6 11.8 30 5.2 1.2 3.3 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 F-box-like PF12937.7 ETS78986.1 - 0.14 12.1 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 F-box-like Frag1 PF10277.9 ETS78987.1 - 1.3e-16 60.8 16.9 1.6e-16 60.5 16.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family MFS_1 PF07690.16 ETS78990.1 - 2.1e-32 112.4 40.4 2.1e-32 112.4 40.4 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS78990.1 - 2.7e-07 29.8 43.7 9.8e-06 24.7 7.1 4.3 3 1 1 4 4 4 4 Sugar (and other) transporter OATP PF03137.20 ETS78990.1 - 0.0058 15.0 2.9 0.0058 15.0 2.9 3.0 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family HMGL-like PF00682.19 ETS78991.1 - 9e-43 146.7 0.0 6.4e-42 143.9 0.0 1.9 1 1 0 1 1 1 1 HMGL-like ATP-synt_ab PF00006.25 ETS78992.1 - 7.5e-66 221.8 0.0 1.1e-65 221.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ETS78992.1 - 3.7e-14 53.0 1.3 6.6e-14 52.2 1.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Aldose_epim PF01263.20 ETS78993.1 - 1.3e-44 152.8 0.6 1.8e-44 152.3 0.6 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Diphthamide_syn PF01866.17 ETS78994.1 - 5.4e-115 384.0 0.0 6.9e-115 383.6 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein COesterase PF00135.28 ETS78995.1 - 2e-76 257.9 0.0 2.8e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS78995.1 - 0.00056 19.8 0.3 0.0038 17.1 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS78995.1 - 0.014 16.0 0.7 0.033 14.8 0.7 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Leu_zip PF15294.6 ETS78996.1 - 0.0012 18.5 18.2 0.0019 17.8 18.2 1.2 1 0 0 1 1 1 1 Leucine zipper Snapin_Pallidin PF14712.6 ETS78996.1 - 0.063 13.7 21.5 0.039 14.4 6.0 3.4 2 1 1 3 3 3 0 Snapin/Pallidin DUF3584 PF12128.8 ETS78996.1 - 0.26 8.8 19.9 0.37 8.3 19.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF812 PF05667.11 ETS78996.1 - 0.28 10.0 19.3 0.43 9.4 19.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Atg14 PF10186.9 ETS78996.1 - 0.29 10.2 20.0 0.65 9.0 20.0 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Wtap PF17098.5 ETS78996.1 - 0.36 10.7 16.8 1.8 8.5 5.7 3.0 3 0 0 3 3 3 0 WTAP/Mum2p family TBCA PF02970.16 ETS78996.1 - 0.38 11.1 15.3 0.47 10.8 3.3 2.7 1 1 1 2 2 2 0 Tubulin binding cofactor A EzrA PF06160.12 ETS78996.1 - 0.68 8.0 18.9 3.9 5.5 18.8 1.8 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA FOXP-CC PF16159.5 ETS78996.1 - 0.88 10.2 9.9 0.26 11.9 1.6 3.6 2 1 1 3 3 3 0 FOXP coiled-coil domain Seryl_tRNA_N PF02403.22 ETS78996.1 - 0.98 9.7 17.7 0.17 12.1 10.3 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CorA PF01544.18 ETS78996.1 - 1 8.6 15.0 0.93 8.8 4.0 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF3450 PF11932.8 ETS78996.1 - 1.2 8.4 23.4 0.4 9.9 11.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TolA_bind_tri PF16331.5 ETS78996.1 - 1.4 9.0 17.4 0.56 10.3 8.3 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation TMPIT PF07851.13 ETS78996.1 - 1.6 7.9 15.2 1.1 8.5 7.2 2.2 1 1 1 2 2 2 0 TMPIT-like protein KxDL PF10241.9 ETS78996.1 - 1.8 8.9 16.2 0.69 10.2 2.4 3.6 1 1 2 3 3 3 0 Uncharacterized conserved protein ATG16 PF08614.11 ETS78996.1 - 1.9 8.7 27.5 12 6.1 27.4 2.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.19 ETS78996.1 - 2.3 6.0 6.8 8.3 4.2 7.7 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF724 PF05266.14 ETS78996.1 - 2.4 7.9 19.4 0.15 11.9 11.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) AAA_13 PF13166.6 ETS78996.1 - 2.8 6.5 14.9 3.9 6.0 14.9 1.3 1 0 0 1 1 1 0 AAA domain LMBR1 PF04791.16 ETS78996.1 - 3 6.7 9.9 4.2 6.2 9.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SHE3 PF17078.5 ETS78996.1 - 8.9 6.0 21.8 0.7 9.6 12.8 2.3 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 FUSC PF04632.12 ETS78996.1 - 9.8 4.6 10.4 13 4.2 8.5 1.8 1 1 0 1 1 1 0 Fusaric acid resistance protein family PNK3P PF08645.11 ETS78997.1 - 4.1e-57 192.4 0.0 6.3e-57 191.8 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 ETS78997.1 - 3.2e-27 95.4 0.0 9.1e-25 87.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS78997.1 - 0.021 15.2 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 ETS78997.1 - 0.034 13.9 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain KTI12 PF08433.10 ETS78997.1 - 0.11 11.9 0.0 1.9 7.9 0.0 2.2 1 1 1 2 2 2 0 Chromatin associated protein KTI12 AAA_11 PF13086.6 ETS78997.1 - 0.19 11.5 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain HET PF06985.11 ETS78998.1 - 1.3e-37 129.4 1.4 3e-37 128.2 1.4 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MDD_C PF18376.1 ETS78999.1 - 1.6e-64 217.1 0.3 2.2e-64 216.7 0.3 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 ETS78999.1 - 1.1e-07 31.9 1.5 1.1e-07 31.9 1.5 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain PhoD PF09423.10 ETS79000.1 - 1e-115 386.6 2.2 1.3e-115 386.2 2.2 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 ETS79000.1 - 2.5e-33 114.5 0.3 5.5e-33 113.4 0.3 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 ETS79000.1 - 7.5e-05 23.2 1.1 7.5e-05 23.2 1.1 2.3 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain ADH_zinc_N PF00107.26 ETS79001.1 - 1e-07 32.0 0.2 2.2e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS79001.1 - 1.7e-06 27.9 0.0 4.5e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 ETS79001.1 - 2e-05 24.4 0.0 4.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated MFS_1 PF07690.16 ETS79002.1 - 2.8e-25 89.0 33.0 2.8e-25 89.0 33.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS79002.1 - 2e-16 59.9 22.4 3.9e-16 59.0 22.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 ETS79002.1 - 0.00055 18.9 4.2 0.00055 18.9 4.2 1.9 1 1 1 2 2 2 1 MFS_1 like family LacAB_rpiB PF02502.18 ETS79002.1 - 0.062 13.3 1.8 0.11 12.5 1.8 1.3 1 0 0 1 1 1 0 Ribose/Galactose Isomerase AAA_22 PF13401.6 ETS79004.1 - 3.6e-07 30.5 0.0 1.1e-05 25.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 ETS79004.1 - 5.4e-07 30.2 0.0 4.1e-06 27.3 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 ETS79004.1 - 0.00028 20.9 0.0 0.0013 18.7 0.0 2.2 1 1 0 1 1 1 1 NACHT domain DUF2075 PF09848.9 ETS79004.1 - 0.0092 15.3 0.0 0.03 13.6 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 ETS79004.1 - 0.028 14.1 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ETS79004.1 - 0.031 13.5 0.0 0.073 12.2 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 ETS79004.1 - 0.031 13.9 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF676 PF05057.14 ETS79004.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) ATPase_2 PF01637.18 ETS79004.1 - 0.16 11.9 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Ank_2 PF12796.7 ETS79005.1 - 8.3e-81 266.7 6.8 3.5e-14 53.1 0.4 8.8 4 2 5 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS79005.1 - 1.4e-58 194.5 12.6 2e-09 37.8 0.1 12.8 8 4 5 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS79005.1 - 1.3e-50 163.4 17.2 3.3e-05 23.9 0.1 16.3 18 0 0 18 18 18 11 Ankyrin repeat Ank PF00023.30 ETS79005.1 - 2.5e-50 166.8 14.9 0.00062 20.1 0.0 15.5 16 1 0 16 16 16 12 Ankyrin repeat Ank_5 PF13857.6 ETS79005.1 - 1.1e-48 162.7 21.7 2.6e-06 27.6 0.2 13.2 5 5 8 13 13 13 10 Ankyrin repeats (many copies) HET PF06985.11 ETS79005.1 - 3.5e-34 118.3 0.6 5.8e-34 117.6 0.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CFEM PF05730.11 ETS79006.1 - 8.6e-12 45.0 12.2 1.4e-11 44.3 12.2 1.3 1 0 0 1 1 1 1 CFEM domain GMC_oxred_N PF00732.19 ETS79007.1 - 1.2e-22 80.6 0.0 5.1e-19 68.8 0.0 2.8 3 0 0 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS79007.1 - 2.4e-20 73.5 0.0 4.8e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 ETS79007.1 - 0.14 11.4 0.0 0.71 9.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS79008.1 - 1.7e-21 76.8 0.9 3.1e-11 43.1 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ETS79008.1 - 3.1e-05 23.4 0.3 0.0015 17.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ETS79008.1 - 0.00018 21.0 0.3 0.16 11.2 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ETS79008.1 - 0.00019 21.6 0.0 0.0004 20.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS79008.1 - 0.00021 21.0 0.6 0.0013 18.4 0.3 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 ETS79008.1 - 0.0057 15.9 0.1 0.17 11.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 ETS79008.1 - 0.0096 15.2 0.0 0.026 13.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS79008.1 - 0.013 16.1 0.0 0.079 13.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ETS79008.1 - 0.013 14.4 0.1 0.033 13.0 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 ETS79008.1 - 0.039 13.0 0.6 0.24 10.4 0.6 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 ETS79008.1 - 0.16 12.4 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Peptidase_S8 PF00082.22 ETS79009.1 - 0.00057 19.3 3.6 0.086 12.1 3.6 3.0 1 1 0 1 1 1 1 Subtilase family DUF4478 PF14793.6 ETS79009.1 - 0.068 13.0 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases zf-Di19 PF05605.12 ETS79010.1 - 0.047 14.0 10.5 1.5 9.1 1.4 3.6 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF4451 PF14616.6 ETS79010.1 - 6.1 7.1 5.4 25 5.1 2.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4451) GFA PF04828.14 ETS79012.1 - 2.1e-12 47.2 11.2 2.4e-08 34.2 1.1 3.3 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme zf-SNAP50_C PF12251.8 ETS79012.1 - 0.11 12.2 4.7 0.13 12.0 1.1 2.2 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal Sugar_tr PF00083.24 ETS79013.1 - 4e-81 273.2 28.6 4.9e-81 272.9 28.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS79013.1 - 4.9e-29 101.4 23.7 4.9e-29 101.4 23.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_membrane_3 PF13748.6 ETS79013.1 - 0.046 12.9 1.0 0.13 11.5 1.0 1.7 1 0 0 1 1 1 0 ABC transporter transmembrane region Glyco_hydro_3_C PF01915.22 ETS79014.1 - 1e-52 179.1 0.0 2.1e-52 178.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS79014.1 - 4.2e-52 177.5 0.0 6.8e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS79014.1 - 4.3e-15 55.6 0.1 1.9e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 ETS79014.1 - 0.016 15.0 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 PA14 domain NACHT PF05729.12 ETS79015.1 - 2.1e-06 27.7 0.2 4.3e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS79015.1 - 0.01 16.2 0.0 0.042 14.2 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain DUF676 PF05057.14 ETS79015.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 ETS79015.1 - 0.31 11.6 2.3 0.74 10.4 0.0 2.7 3 1 0 3 3 3 0 Alpha/beta hydrolase family Acetyltransf_8 PF13523.6 ETS79016.1 - 6.7e-42 142.6 0.0 1.1e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MCU PF04678.13 ETS79017.1 - 9.8e-22 77.9 0.0 9.8e-22 77.9 0.0 3.1 3 0 0 3 3 3 1 Mitochondrial calcium uniporter Hydant_A_N PF05378.13 ETS79017.1 - 0.51 10.0 2.6 0.61 9.8 0.1 2.2 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase N-terminal region Asp PF00026.23 ETS79018.1 - 2.9e-52 178.1 0.0 3.5e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS79018.1 - 9.2e-08 32.5 1.0 9.7e-07 29.2 1.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ETS79018.1 - 0.0088 16.7 0.3 5 7.8 0.2 2.8 2 1 0 2 2 2 2 Aspartyl protease S36_mt PF10937.8 ETS79019.1 - 8.1e-40 137.0 0.4 1.1e-39 136.6 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial MCR_C PF04609.12 ETS79020.1 - 0.015 14.4 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C Fructosamin_kin PF03881.14 ETS79021.1 - 0.0084 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase DUF3433 PF11915.8 ETS79024.1 - 7.8e-18 64.7 25.5 1.9e-13 50.7 0.9 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Lipocalin_9 PF17186.4 ETS79025.1 - 1.5e-08 34.9 0.6 4.5e-08 33.4 0.3 2.0 2 0 0 2 2 2 1 Lipocalin-like domain CrtC PF07143.11 ETS79025.1 - 2.6e-05 25.0 0.0 5.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 CrtC N-terminal lipocalin domain Fungal_trans PF04082.18 ETS79026.1 - 2.2e-11 43.3 2.0 3.9e-11 42.5 2.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 ETS79027.1 - 5.6e-53 180.3 0.0 7.5e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 KR PF08659.10 ETS79028.1 - 1.7e-28 99.8 0.3 1.6e-21 77.0 0.0 2.4 1 1 1 2 2 2 2 KR domain ADH_zinc_N PF00107.26 ETS79028.1 - 4.3e-09 36.4 1.0 4.1e-07 30.0 0.2 2.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS79028.1 - 7.2e-05 23.9 0.0 0.00013 23.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS79028.1 - 0.00096 19.0 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 ETS79029.1 - 4.4e-13 49.4 0.1 6.7e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site Alpha-E PF04168.12 ETS79029.1 - 0.018 14.8 0.1 0.018 14.8 0.1 1.1 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Ank_2 PF12796.7 ETS79030.1 - 2.7e-80 265.0 12.1 4.2e-15 56.1 0.0 8.4 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS79030.1 - 1.1e-67 223.5 18.8 3.8e-10 40.1 0.0 11.2 4 4 6 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 ETS79030.1 - 9e-57 187.2 22.6 1.9e-05 24.9 0.1 14.2 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.6 ETS79030.1 - 3.4e-56 186.6 12.5 4.8e-07 29.9 0.0 11.6 4 2 8 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS79030.1 - 6.4e-52 167.5 10.9 0.0092 16.4 0.0 15.0 15 0 0 15 15 15 13 Ankyrin repeat NACHT PF05729.12 ETS79030.1 - 3.8e-08 33.4 0.1 1.3e-07 31.7 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS79030.1 - 6e-05 23.5 2.0 0.00013 22.4 0.1 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ETS79030.1 - 0.003 17.8 0.1 0.012 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain 3HCDH_RFF PF18321.1 ETS79030.1 - 0.14 12.6 4.4 10 6.6 0.0 4.6 5 0 0 5 5 5 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain DUF756 PF05506.12 ETS79030.1 - 0.15 13.0 0.7 0.66 10.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF756) Bac_rhamnosid6H PF17389.2 ETS79031.1 - 1.5e-13 50.7 0.8 4.1e-12 46.0 1.3 2.1 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 ETS79031.1 - 9.6e-05 21.4 3.1 0.00019 20.4 1.4 1.9 2 0 0 2 2 2 1 Trehalase Bac_surface_Ag PF01103.23 ETS79031.1 - 0.012 15.2 1.2 0.029 13.9 1.2 1.6 1 0 0 1 1 1 0 Surface antigen Bac_rhamnosid PF05592.11 ETS79031.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Mal_decarbox_Al PF16957.5 ETS79031.1 - 0.25 9.6 0.1 0.37 9.1 0.1 1.1 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter Bac_rhamnosid_N PF08531.10 ETS79032.1 - 1.1e-45 155.6 0.5 1.7e-45 154.9 0.5 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 ETS79032.1 - 0.00083 19.3 0.0 0.0028 17.6 0.0 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid6H PF17389.2 ETS79033.1 - 8.5e-86 288.3 0.1 1.1e-85 287.9 0.1 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 ETS79033.1 - 3.3e-10 39.6 0.0 6e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF608 PF04685.13 ETS79033.1 - 0.066 12.4 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region Bac_rhamnosid6H PF17389.2 ETS79034.1 - 1.3e-75 254.8 9.2 1.3e-75 254.8 9.2 1.7 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 ETS79034.1 - 7.3e-43 146.4 0.1 1.6e-42 145.3 0.1 1.6 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 ETS79034.1 - 6.6e-19 67.8 0.0 1.8e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 ETS79034.1 - 2e-14 53.1 0.1 5.1e-14 51.8 0.1 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain CorA PF01544.18 ETS79035.1 - 1.1e-14 54.4 0.6 3.5e-14 52.8 0.4 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein SelB-wing_1 PF09105.10 ETS79036.1 - 0.083 12.9 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 Elongation factor SelB, winged helix DUF2793 PF10983.8 ETS79036.1 - 0.12 12.3 0.0 0.59 10.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2793) FliD_C PF07195.12 ETS79036.1 - 0.33 10.3 0.1 0.33 10.3 0.1 2.4 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus BRE1 PF08647.11 ETS79037.1 - 0.12 12.4 2.7 0.3 11.2 2.7 1.6 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Trimer_CC PF08954.11 ETS79038.1 - 0.09 12.4 2.8 0.45 10.1 0.0 2.6 3 0 0 3 3 3 0 Trimerisation motif adh_short PF00106.25 ETS79039.1 - 5.8e-39 133.6 0.0 7.9e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS79039.1 - 9.8e-27 94.0 0.1 1.3e-26 93.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS79039.1 - 5.2e-05 23.2 0.4 9.7e-05 22.4 0.4 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ETS79039.1 - 9.3e-05 22.4 0.4 0.00018 21.5 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ETS79039.1 - 0.0034 16.5 0.1 0.0054 15.9 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.15 ETS79039.1 - 0.015 15.2 0.3 0.022 14.6 0.3 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.21 ETS79039.1 - 0.063 12.7 0.4 0.27 10.6 0.4 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sec16_C PF12931.7 ETS79040.1 - 4.4e-11 43.0 1.3 2e-10 40.8 0.6 2.3 2 1 0 2 2 2 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 ETS79040.1 - 1.7e-08 34.4 0.0 1.7e-08 34.4 0.0 4.3 5 1 0 5 5 5 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 ETS79040.1 - 6.8e-06 26.7 0.1 0.056 14.3 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat PALB2_WD40 PF16756.5 ETS79040.1 - 0.014 14.3 0.1 0.18 10.7 0.0 2.2 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Prp18 PF02840.15 ETS79040.1 - 0.036 14.1 0.1 0.093 12.8 0.1 1.7 1 1 0 1 1 1 0 Prp18 domain RRM_1 PF00076.22 ETS79041.1 - 6.3e-17 61.2 0.0 9.5e-17 60.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ETS79041.1 - 4.6e-05 23.5 0.0 6.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 ETS79041.1 - 0.0018 18.2 0.0 0.0046 16.9 0.0 1.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 ETS79041.1 - 0.054 13.1 0.0 0.092 12.3 0.0 1.3 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LD_cluster3 PF18180.1 ETS79041.1 - 0.086 12.5 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 SLOG cluster3 family RRM_occluded PF16842.5 ETS79041.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif B12D PF06522.11 ETS79042.1 - 0.00074 19.3 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit COX6B PF02297.17 ETS79043.1 - 1.1e-18 67.2 4.7 1.3e-18 67.0 4.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 ETS79043.1 - 0.013 15.5 2.4 0.019 15.0 2.1 1.5 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, ketoacyl-synt PF00109.26 ETS79043.1 - 0.056 13.0 0.0 0.056 13.0 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain APOBEC_C PF05240.14 ETS79043.1 - 0.07 13.1 2.3 0.062 13.3 1.1 1.6 1 1 0 1 1 1 0 APOBEC-like C-terminal domain CHCH PF06747.13 ETS79043.1 - 0.089 12.9 0.8 0.24 11.6 0.8 1.7 1 1 0 1 1 1 0 CHCH domain Sde2_N_Ubi PF13019.6 ETS79044.1 - 1.5e-61 207.0 0.4 2.1e-61 206.5 0.4 1.2 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Phage_Mu_F PF04233.14 ETS79044.1 - 0.42 11.4 3.0 0.77 10.5 2.6 1.6 1 1 0 1 1 1 0 Phage Mu protein F like protein MPM1 PF17234.2 ETS79044.1 - 6.1 7.1 8.2 14 5.9 8.2 1.6 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 S10_plectin PF03501.15 ETS79045.1 - 2.4e-42 142.9 0.1 2.9e-42 142.6 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain ADH_N PF08240.12 ETS79046.1 - 5.7e-33 113.1 0.8 1.2e-32 112.1 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS79046.1 - 9.5e-15 54.7 0.0 1.7e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS79046.1 - 3.9e-11 42.9 0.0 5.7e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ETS79046.1 - 1.7e-08 35.6 0.0 2.9e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 ETS79046.1 - 7.6e-05 22.1 0.0 0.00023 20.5 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 ETS79046.1 - 0.019 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 ETS79046.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 ETS79046.1 - 0.12 13.0 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 ETS79046.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.6 ETS79046.1 - 0.15 11.3 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N_2 PF16884.5 ETS79046.1 - 0.17 11.8 0.0 0.7 9.8 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase adh_short PF00106.25 ETS79047.1 - 2.1e-30 105.6 0.0 2.8e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS79047.1 - 1.7e-25 89.9 0.0 2e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS79047.1 - 0.00014 21.8 0.1 0.0019 18.1 0.1 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS79047.1 - 0.00032 20.3 0.0 0.00045 19.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ETS79047.1 - 0.0057 15.8 0.0 0.0075 15.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 ETS79047.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ETS79047.1 - 0.12 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase BING4CT PF08149.11 ETS79049.1 - 1.8e-39 133.4 0.0 1.8e-34 117.4 0.0 3.5 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 ETS79049.1 - 1.6e-06 28.3 0.1 6.5 7.1 0.0 5.8 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ETS79049.1 - 0.0003 21.5 0.0 0.057 14.3 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat RIBIOP_C PF04950.12 ETS79050.1 - 1.3e-110 369.4 0.0 2.3e-110 368.6 0.0 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 ETS79050.1 - 5.9e-21 74.4 0.0 2e-20 72.7 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain DUF2931 PF11153.8 ETS79050.1 - 0.1 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) PSP1 PF04468.12 ETS79051.1 - 1.1e-26 92.9 0.9 1.8e-26 92.2 0.9 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Lactamase_B PF00753.27 ETS79052.1 - 1.5e-20 74.0 3.3 2e-20 73.6 3.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS79052.1 - 9.5e-05 22.0 0.4 0.00017 21.2 0.4 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Nfu_N PF08712.11 ETS79053.1 - 2.2e-29 101.4 0.0 6.4e-29 99.8 0.0 1.8 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 ETS79053.1 - 2.3e-26 91.7 0.0 3.9e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain zf-HIT PF04438.16 ETS79054.1 - 0.0024 17.7 4.2 0.0039 17.0 4.2 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-UDP PF14569.6 ETS79054.1 - 0.1 12.7 2.9 0.18 11.9 2.9 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger cobW PF02492.19 ETS79056.1 - 8.5e-35 119.9 0.0 1.3e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 ETS79056.1 - 3.3e-06 26.3 1.5 5.6e-05 22.3 1.5 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 ETS79056.1 - 0.0022 18.5 0.0 0.003 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 ETS79056.1 - 0.0047 17.0 0.0 0.014 15.4 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase ResIII PF04851.15 ETS79056.1 - 0.075 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.23 ETS79056.1 - 0.094 12.8 0.0 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 ETS79056.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF3176 PF11374.8 ETS79057.1 - 9.3e-32 109.4 1.7 9.3e-32 109.4 1.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Glycophorin_A PF01102.18 ETS79057.1 - 0.021 15.0 0.9 0.58 10.4 0.0 2.8 3 0 0 3 3 3 0 Glycophorin A ADH_zinc_N PF00107.26 ETS79058.1 - 6.8e-10 39.0 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS79058.1 - 2.1e-08 34.0 0.5 8.6e-08 32.0 0.5 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ETS79058.1 - 0.0027 17.6 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Spc7_N PF15402.6 ETS79060.1 - 0.025 12.9 8.3 0.028 12.7 8.3 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Arc_PepC_II PF06847.11 ETS79061.1 - 0.17 12.4 1.1 0.47 11.0 0.5 2.0 2 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Prominin PF05478.11 ETS79061.1 - 0.2 9.6 2.2 0.29 9.0 1.9 1.3 1 1 0 1 1 1 0 Prominin Fib_alpha PF08702.10 ETS79061.1 - 1.5 9.0 8.5 1.3 9.2 5.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ZYG-11_interact PF05884.12 ETS79061.1 - 2.8 7.3 6.0 12 5.2 1.2 2.4 1 1 1 2 2 2 0 Interactor of ZYG-11 DUF148 PF02520.17 ETS79061.1 - 4.7 7.3 9.3 2.7 8.1 2.6 2.9 3 1 1 4 4 4 0 Domain of unknown function DUF148 Ribosomal_L15e PF00827.17 ETS79062.1 - 4.9e-90 300.4 11.0 6e-90 300.1 11.0 1.0 1 0 0 1 1 1 1 Ribosomal L15 PUF PF00806.19 ETS79063.1 - 1.4e-53 175.7 13.5 1.4e-07 30.8 0.5 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 ETS79063.1 - 0.00053 20.4 0.1 1.2 9.4 0.0 3.7 2 1 1 3 3 3 2 CPL (NUC119) domain RNA_pol_Rpb2_6 PF00562.28 ETS79064.1 - 2.3e-118 395.7 0.0 3.7e-118 395.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ETS79064.1 - 9.5e-51 172.2 0.0 1.5e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 ETS79064.1 - 1.1e-32 112.3 0.5 2.3e-32 111.2 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 ETS79064.1 - 1.8e-25 89.7 0.0 5e-25 88.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 ETS79064.1 - 3.3e-21 75.3 0.1 8.5e-21 74.0 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 ETS79064.1 - 2.3e-20 72.5 0.0 4.8e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 ETS79064.1 - 1.9e-11 44.3 0.5 6e-11 42.7 0.5 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 CEND1 PF15677.5 ETS79065.1 - 0.0038 17.8 0.9 0.0038 17.8 0.9 2.1 2 0 0 2 2 2 1 Cell cycle exit and neuronal differentiation protein 1 TrbC PF04956.13 ETS79065.1 - 0.086 13.1 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 TrbC/VIRB2 family TrbL PF04610.14 ETS79065.1 - 0.11 12.3 1.9 0.19 11.5 1.9 1.3 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Alpha_GJ PF03229.13 ETS79065.1 - 0.28 11.7 8.4 0.05 14.2 2.1 2.6 2 0 0 2 2 2 0 Alphavirus glycoprotein J Rad51 PF08423.11 ETS79066.1 - 1.7e-42 145.5 0.0 3.9e-40 137.7 0.0 2.1 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 ETS79066.1 - 6.1e-07 29.2 0.0 1.6e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 ETS79066.1 - 1.3e-06 28.0 0.0 2.7e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 KaiC RecA PF00154.21 ETS79066.1 - 2.9e-05 23.7 0.0 0.00026 20.6 0.0 2.0 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_24 PF13479.6 ETS79066.1 - 0.0003 20.6 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ETS79066.1 - 0.0019 18.5 0.0 0.0063 16.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS79066.1 - 0.09 13.1 0.0 0.19 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 ETS79066.1 - 0.1 13.1 0.2 0.18 12.3 0.2 1.6 1 1 0 1 1 1 0 ABC transporter MMU163 PF17119.5 ETS79067.1 - 2.9e-76 255.9 8.4 2.7e-56 190.5 2.2 2.1 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis DUF5058 PF16481.5 ETS79067.1 - 0.19 11.4 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) Ras PF00071.22 ETS79068.1 - 4.2e-65 218.3 0.5 5.2e-65 218.0 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS79068.1 - 1.6e-35 121.9 0.1 2.7e-35 121.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS79068.1 - 5.4e-16 58.5 0.1 7.2e-16 58.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ETS79068.1 - 5.5e-05 23.2 0.0 0.00022 21.3 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETS79068.1 - 6.2e-05 23.0 0.2 0.19 11.6 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 ETS79068.1 - 0.0002 21.0 0.2 0.00054 19.6 0.2 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ETS79068.1 - 0.00049 19.5 0.1 0.0007 19.0 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 ETS79068.1 - 0.00099 18.6 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 ETS79068.1 - 0.005 17.3 0.0 0.35 11.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 ETS79068.1 - 0.012 15.2 0.0 0.063 12.8 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 ETS79068.1 - 0.015 15.7 0.0 0.03 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ETS79068.1 - 0.066 13.5 0.0 0.13 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ETS79068.1 - 0.087 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 ETS79068.1 - 0.089 12.2 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 ETS79068.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 ETS79068.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Methyltransf_2 PF00891.18 ETS79069.1 - 9.6e-24 83.8 0.3 8.9e-22 77.4 0.3 2.3 1 1 0 1 1 1 1 O-methyltransferase domain HTH_31 PF13560.6 ETS79069.1 - 0.051 13.9 0.0 0.68 10.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Methyltransf_25 PF13649.6 ETS79069.1 - 0.053 14.2 0.0 0.38 11.5 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 ETS79069.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FMO-like PF00743.19 ETS79070.1 - 1.1e-32 113.2 0.0 8.4e-30 103.7 0.0 3.0 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ETS79070.1 - 1.7e-20 73.5 0.0 2.3e-16 60.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS79070.1 - 1.6e-18 67.0 0.0 6.9e-16 58.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS79070.1 - 5.6e-13 48.8 0.0 7.8e-10 38.4 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ETS79070.1 - 1.1e-07 32.0 0.0 1.9e-06 28.0 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ETS79070.1 - 9.5e-05 21.9 0.2 0.00033 20.1 0.0 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS79070.1 - 0.00014 22.3 0.6 0.32 11.6 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS79070.1 - 0.00047 19.5 0.4 0.0052 16.1 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 ETS79070.1 - 0.00058 18.7 1.8 0.0033 16.2 0.3 2.4 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.17 ETS79070.1 - 0.00062 19.1 0.1 0.0059 15.9 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 ETS79070.1 - 0.0011 18.7 2.4 0.28 10.7 2.4 3.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS79070.1 - 0.0012 18.8 1.2 0.23 11.4 0.0 3.1 3 2 0 3 3 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ETS79070.1 - 0.0017 17.6 0.1 0.0055 15.8 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 ETS79070.1 - 0.043 12.9 0.3 6.6 5.7 0.2 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 ETS79070.1 - 0.074 13.5 0.2 14 6.2 0.0 2.7 2 2 0 2 2 2 0 Putative NAD(P)-binding PI-PLC-X PF00388.19 ETS79070.1 - 0.082 12.5 0.0 6.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain DUF1987 PF09345.10 ETS79071.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) Carn_acyltransf PF00755.20 ETS79072.1 - 1.3e-206 687.8 0.0 2.6e-206 686.8 0.0 1.5 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Utp14 PF04615.13 ETS79074.1 - 0.0044 15.7 21.0 0.0057 15.3 21.0 1.1 1 0 0 1 1 1 1 Utp14 protein DUF406 PF04175.12 ETS79074.1 - 0.42 11.1 3.9 0.29 11.6 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF406) Nucleo_P87 PF07267.11 ETS79074.1 - 5.2 5.8 9.7 7.3 5.3 9.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 GrpE PF01025.19 ETS79075.1 - 1.3e-47 161.6 5.1 1.7e-47 161.2 5.1 1.1 1 0 0 1 1 1 1 GrpE BicD PF09730.9 ETS79075.1 - 0.0069 14.9 4.2 0.009 14.5 4.2 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D FAM184 PF15665.5 ETS79075.1 - 0.049 13.4 5.3 0.083 12.7 5.3 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Peptidase_S49 PF01343.18 ETS79075.1 - 0.14 12.1 1.1 0.21 11.5 1.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 RNA_pol_A_bac PF01000.26 ETS79076.1 - 7.1e-31 106.9 0.0 1.1e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 ETS79076.1 - 7.1e-18 63.8 0.0 1e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.6 ETS79076.1 - 0.012 15.3 0.0 6.6 6.6 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Mito_carr PF00153.27 ETS79077.1 - 6.9e-52 173.4 0.3 8.4e-22 76.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2d PF01409.20 ETS79078.1 - 1.3e-48 165.7 0.1 6.5e-25 88.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 ETS79078.1 - 1.4e-25 89.6 0.0 2.6e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain p450 PF00067.22 ETS79079.1 - 1.6e-39 135.9 0.0 1e-30 106.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Calcipressin PF04847.12 ETS79080.1 - 4.1e-51 173.4 0.0 5e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Calcipressin F-box PF00646.33 ETS79081.1 - 0.0022 17.8 0.1 0.0066 16.3 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ETS79081.1 - 0.14 12.1 0.1 0.43 10.5 0.1 1.9 1 0 0 1 1 1 0 F-box-like FbpC_C_terminal PF17845.1 ETS79082.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 FbpC C-terminal regulatory nucleotide binding domain RFC1 PF08519.12 ETS79084.1 - 2.2e-57 193.6 0.2 1.5e-56 190.9 0.0 2.2 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 ETS79084.1 - 3.6e-15 56.1 0.0 8.3e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 ETS79084.1 - 3.9e-09 37.0 0.0 1.1e-08 35.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ETS79084.1 - 4.5e-06 26.7 0.0 9.7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 ETS79084.1 - 0.0019 18.0 0.0 0.0069 16.2 0.0 2.0 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_33 PF13671.6 ETS79084.1 - 0.0031 17.7 0.0 0.012 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS79084.1 - 0.0068 16.8 0.1 0.033 14.6 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 ETS79084.1 - 0.0097 15.6 0.0 0.0097 15.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ETS79084.1 - 0.012 16.2 2.0 0.034 14.7 0.1 2.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ETS79084.1 - 0.024 14.9 0.0 0.24 11.6 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ETS79084.1 - 0.041 14.1 0.5 0.22 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ETS79084.1 - 0.044 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 ETS79084.1 - 0.048 13.4 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ETS79084.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 ETS79084.1 - 0.079 12.9 0.0 0.49 10.3 0.0 2.3 2 0 0 2 2 2 0 NTPase Ribosomal_L16 PF00252.18 ETS79085.1 - 2.7e-32 111.5 0.2 3.8e-32 111.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e OAD_gamma PF04277.13 ETS79087.1 - 0.012 16.2 0.0 0.021 15.4 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Nckap1 PF09735.9 ETS79087.1 - 0.093 10.7 0.0 0.1 10.5 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein FAM176 PF14851.6 ETS79087.1 - 0.15 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 FAM176 family Ribosomal_S5_C PF03719.15 ETS79088.1 - 4.1e-21 74.2 0.1 1.9e-20 72.1 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 ETS79088.1 - 1.2e-18 66.8 0.8 2.5e-18 65.8 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain ArsR PF09824.9 ETS79088.1 - 0.059 13.0 0.1 0.12 12.0 0.1 1.5 1 0 0 1 1 1 0 ArsR transcriptional regulator DASH_Dad3 PF08656.10 ETS79089.1 - 1.2e-33 115.0 1.0 1.4e-33 114.8 1.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 DASH_Hsk3 PF08227.11 ETS79089.1 - 0.044 14.1 0.1 0.079 13.3 0.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like MetOD2 PF18548.1 ETS79089.1 - 0.09 12.9 0.2 0.13 12.4 0.2 1.3 1 0 0 1 1 1 0 Metanogen output domain 2 RhoGEF PF00621.20 ETS79090.1 - 0.017 15.3 0.6 5.2 7.3 0.0 2.5 2 0 0 2 2 2 0 RhoGEF domain Ank_2 PF12796.7 ETS79090.1 - 0.061 13.9 0.0 5.4 7.7 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) DUF1664 PF07889.12 ETS79090.1 - 0.65 10.0 5.0 0.44 10.6 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ApoLp-III PF07464.11 ETS79090.1 - 0.72 9.9 5.1 13 5.9 0.1 2.7 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF948 PF06103.11 ETS79090.1 - 0.91 9.8 3.1 61 4.0 0.0 3.5 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Cortex-I_coil PF09304.10 ETS79090.1 - 1.2 9.4 5.8 1.1 9.6 1.9 2.8 1 1 1 2 2 2 0 Cortexillin I, coiled coil TolA_bind_tri PF16331.5 ETS79090.1 - 4.8 7.3 13.2 2.1 8.5 1.2 3.8 3 0 0 3 3 3 0 TolA binding protein trimerisation COesterase PF00135.28 ETS79091.1 - 6.5e-62 210.0 1.2 8.6e-62 209.6 1.2 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS79091.1 - 0.00044 20.2 0.3 0.0013 18.6 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 ETS79091.1 - 0.00049 19.8 0.2 0.00098 18.8 0.2 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Snf7 PF03357.21 ETS79092.1 - 2.3e-16 59.9 6.1 2.9e-16 59.5 6.1 1.1 1 0 0 1 1 1 1 Snf7 CS PF04969.16 ETS79093.1 - 1.7e-06 29.0 0.1 2.5e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 CS domain Cwf_Cwc_15 PF04889.12 ETS79093.1 - 7.9e-05 22.5 5.1 0.0001 22.1 5.1 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein PARP PF00644.20 ETS79094.1 - 1.1e-11 44.8 0.2 2.8e-11 43.4 0.2 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 ETS79094.1 - 7.8e-07 28.8 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme COG5 PF10392.9 ETS79095.1 - 0.00014 22.1 0.4 0.00014 22.1 0.4 2.1 3 0 0 3 3 3 1 Golgi transport complex subunit 5 2CSK_N PF08521.10 ETS79095.1 - 0.041 14.0 0.1 0.069 13.3 0.1 1.3 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal LPD30 PF18850.1 ETS79096.1 - 0.066 13.0 0.8 0.091 12.5 0.8 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 Membr_traf_MHD PF10540.9 ETS79096.1 - 0.073 13.2 0.5 0.091 12.9 0.5 1.3 1 0 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain Sds3 PF08598.11 ETS79097.1 - 8.4e-19 68.4 14.6 3.5e-18 66.4 14.6 2.1 1 1 0 1 1 1 1 Sds3-like RPN6_N PF18055.1 ETS79100.1 - 1.4e-45 154.4 4.2 1.7e-45 154.1 0.8 2.7 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 ETS79100.1 - 1.2e-20 73.9 0.4 4.2e-20 72.2 0.2 2.1 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 ETS79100.1 - 2.7e-09 36.6 1.0 6.7e-09 35.3 1.0 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain DDRGK PF09756.9 ETS79100.1 - 0.0003 20.4 0.3 0.00059 19.5 0.3 1.4 1 0 0 1 1 1 1 DDRGK domain TPR_MalT PF17874.1 ETS79100.1 - 0.00099 18.6 1.8 0.00099 18.6 1.8 2.2 1 1 1 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 ETS79100.1 - 0.0012 18.7 4.3 0.75 10.0 0.4 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 ETS79100.1 - 0.0015 18.8 19.1 0.015 15.6 2.4 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 ETS79100.1 - 0.029 14.5 2.9 36 4.8 0.0 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF3496 PF12001.8 ETS79100.1 - 0.085 13.2 2.4 0.31 11.4 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) TPR_1 PF00515.28 ETS79100.1 - 0.28 11.1 4.2 8.6 6.4 0.3 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 ETS79100.1 - 2.7 8.8 10.2 17 6.3 0.1 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 ETS79101.1 - 1.8e-30 104.5 7.8 2.6e-05 24.9 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.14 ETS79101.1 - 1.6e-29 102.0 17.9 2.8e-29 101.2 17.9 1.4 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 ETS79101.1 - 3.8e-08 33.5 0.4 0.017 15.4 0.0 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS79101.1 - 9.2e-05 21.6 0.1 0.02 13.9 0.0 3.0 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ETS79101.1 - 0.00012 22.0 1.9 0.0011 18.9 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 ETS79101.1 - 0.00061 19.8 0.0 7.3 6.7 0.0 4.3 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region RICH PF05062.12 ETS79101.1 - 0.15 12.5 5.5 0.28 11.5 5.5 1.5 1 0 0 1 1 1 0 RICH domain Cupin_2 PF07883.11 ETS79102.1 - 0.0018 17.9 0.0 0.096 12.4 0.0 2.4 1 1 0 1 1 1 1 Cupin domain MFS_1 PF07690.16 ETS79103.1 - 8.2e-14 51.3 20.4 1.6e-13 50.4 20.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS79103.1 - 0.0093 15.3 14.3 0.043 13.1 14.6 1.7 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 ETS79104.1 - 0.0008 18.4 11.9 0.0008 18.4 11.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily ABC2_membrane_3 PF12698.7 ETS79104.1 - 0.0038 16.4 0.6 0.0057 15.8 0.6 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF4064 PF13273.6 ETS79104.1 - 0.038 14.3 4.5 0.39 11.0 4.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF1686 PF07937.11 ETS79104.1 - 0.057 13.3 0.1 0.086 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) OppC_N PF12911.7 ETS79104.1 - 3.8 7.6 7.1 1.8 8.6 1.7 2.7 1 1 1 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF3792 PF12670.7 ETS79104.1 - 4.5 7.5 16.3 4.8 7.4 3.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) Candida_ALS PF05792.13 ETS79105.1 - 0.0038 17.8 18.9 0.0038 17.8 18.9 10.7 5 1 0 5 5 5 2 Candida agglutinin-like (ALS) adh_short PF00106.25 ETS79108.1 - 1.9e-37 128.7 0.1 2.6e-37 128.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS79108.1 - 1.8e-28 99.7 0.0 2.5e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS79108.1 - 3.8e-09 36.7 2.7 9.5e-08 32.2 2.7 2.2 1 1 0 1 1 1 1 KR domain HI0933_like PF03486.14 ETS79108.1 - 0.038 12.7 0.0 0.26 9.9 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein NMT1_3 PF16868.5 ETS79108.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family Pkinase PF00069.25 ETS79109.1 - 1.4e-10 41.0 0.0 2.2e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS79109.1 - 0.00087 18.7 0.0 0.003 16.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PDEase_II PF02112.15 ETS79109.1 - 0.076 12.1 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Glyco_hydro_72 PF03198.14 ETS79110.1 - 3.1e-97 325.6 0.1 5.1e-97 324.9 0.1 1.3 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 ETS79110.1 - 0.062 12.4 0.1 0.092 11.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 ETS79110.1 - 0.12 11.8 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) RGS PF00615.19 ETS79112.1 - 0.00039 20.7 0.1 0.0046 17.2 0.0 2.2 2 1 0 2 2 2 1 Regulator of G protein signaling domain RGS PF00615.19 ETS79114.1 - 1e-12 48.3 0.0 1.5e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain WD40 PF00400.32 ETS79116.1 - 7.8e-23 80.3 16.9 7.8e-08 32.9 0.1 6.9 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS79116.1 - 7.3e-05 23.0 1.3 3.3 8.1 0.1 4.9 4 2 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS79116.1 - 0.22 10.4 0.4 2.1 7.2 0.2 2.5 2 2 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 ETS79116.1 - 0.26 10.3 0.7 0.42 9.6 0.7 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Pribosyl_synth PF14572.6 ETS79117.1 - 8.6e-41 140.0 1.8 2.2e-35 122.3 0.5 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 ETS79117.1 - 1.7e-30 105.3 0.0 3.6e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 ETS79117.1 - 2.7e-13 49.7 0.2 4.4e-13 49.1 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ETS79117.1 - 0.056 12.9 0.1 0.088 12.2 0.1 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase RNA_pol_Rpb4 PF03874.16 ETS79118.1 - 2.8e-19 69.7 0.0 3.4e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 SWIRM-assoc_2 PF16496.5 ETS79118.1 - 0.055 12.3 0.1 0.08 11.8 0.1 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Ras PF00071.22 ETS79119.1 - 2.2e-17 63.1 0.0 5.1e-17 61.9 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 ETS79119.1 - 1.3e-06 28.6 0.0 2.5e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS79119.1 - 0.031 13.7 0.1 4.8 6.6 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_24 PF13479.6 ETS79119.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 ETS79119.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit PseudoU_synth_1 PF01416.20 ETS79120.1 - 6e-34 116.7 0.0 9e-33 113.0 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase PIG-H PF10181.9 ETS79121.1 - 2.3e-27 94.6 0.1 3.5e-27 94.1 0.1 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component MatC_N PF07158.11 ETS79121.1 - 0.052 13.6 1.2 0.1 12.7 0.4 1.8 2 0 0 2 2 2 0 Dicarboxylate carrier protein MatC N-terminus ATP_bind_3 PF01171.20 ETS79125.1 - 4.7e-40 137.3 0.1 9.2e-39 133.1 0.1 2.2 1 1 0 1 1 1 1 PP-loop family Peptidase_M61 PF05299.12 ETS79125.1 - 0.0044 17.4 0.7 0.021 15.2 0.7 2.2 1 1 0 1 1 1 1 M61 glycyl aminopeptidase Peptidase_M1 PF01433.20 ETS79125.1 - 0.0067 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Asn_synthase PF00733.21 ETS79125.1 - 0.0089 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Asparagine synthase DUF5106 PF17127.4 ETS79125.1 - 0.021 15.1 0.1 0.13 12.5 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5106) NAD_synthase PF02540.17 ETS79125.1 - 0.063 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD synthase SprT-like PF10263.9 ETS79125.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 SprT-like family SnoaL_2 PF12680.7 ETS79126.1 - 3.1e-07 31.0 0.0 4.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ETS79126.1 - 0.0019 18.6 0.0 0.0029 18.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Tannase PF07519.11 ETS79127.1 - 2.8e-85 287.0 0.3 3.6e-85 286.6 0.3 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 ETS79127.1 - 0.00039 19.8 0.0 0.002 17.5 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS79127.1 - 0.0029 17.3 0.3 0.0054 16.4 0.3 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS79127.1 - 0.017 14.6 0.1 0.28 10.6 0.2 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family adh_short_C2 PF13561.6 ETS79128.1 - 5.3e-60 202.9 3.6 6.2e-60 202.7 3.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS79128.1 - 4.2e-46 156.9 1.9 5.1e-46 156.6 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS79128.1 - 1.9e-10 40.9 2.3 2.6e-10 40.5 2.3 1.2 1 0 0 1 1 1 1 KR domain ZapC PF07126.12 ETS79128.1 - 0.0049 16.5 0.0 0.0071 15.9 0.0 1.2 1 0 0 1 1 1 1 Cell-division protein ZapC AdoHcyase_NAD PF00670.21 ETS79128.1 - 0.077 13.1 0.7 0.16 12.0 0.2 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glyco_hyd_65N_2 PF14498.6 ETS79129.1 - 3.8e-52 177.5 0.2 5.4e-52 177.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Rdx PF10262.9 ETS79129.1 - 0.029 14.5 0.0 13 6.0 0.0 3.9 4 1 0 4 4 4 0 Rdx family Mito_carr PF00153.27 ETS79130.1 - 2.6e-44 149.1 8.0 2.6e-16 59.3 0.1 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 ETS79130.1 - 0.013 14.7 1.0 0.32 10.1 0.2 2.4 2 0 0 2 2 2 0 Gammaproteobacterial serine protease DUF3337 PF11816.8 ETS79131.1 - 2.8e-57 193.3 0.0 8.1e-57 191.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 ETS79131.1 - 1.1e-21 76.7 17.1 6.9e-06 26.7 0.1 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 ETS79131.1 - 0.004 15.9 3.0 0.0045 15.7 0.1 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 ETS79131.1 - 0.012 15.9 0.8 1.4 9.3 0.1 3.7 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS79131.1 - 0.13 11.2 0.4 3.6 6.5 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Baculo_PEP_C PF04513.12 ETS79132.1 - 0.24 11.5 4.8 0.48 10.5 4.8 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PuR_N PF09182.10 ETS79132.1 - 0.3 11.1 3.4 0.42 10.6 2.5 1.8 1 1 0 1 1 1 0 Bacterial purine repressor, N-terminal TPR_2 PF07719.17 ETS79133.1 - 3.1e-05 23.7 7.8 0.075 13.2 0.3 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 ETS79133.1 - 0.001 18.8 4.7 0.7 9.8 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS79133.1 - 0.0037 17.7 3.4 1.4 9.5 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 ETS79133.1 - 0.097 12.6 1.7 6.7 6.7 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 ETS79133.1 - 0.34 11.0 3.7 9.8 6.5 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 ETS79133.1 - 0.64 10.4 5.4 0.46 10.8 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 ETS79133.1 - 1.2 10.1 7.0 11 7.2 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 ETS79133.1 - 2.1 8.7 6.4 0.38 11.1 0.3 2.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ETS79133.1 - 2.8 8.8 8.9 1.1 10.1 0.4 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Arb2 PF09757.9 ETS79135.1 - 2.3e-98 328.4 0.0 3.6e-98 327.8 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 ETS79135.1 - 1.9e-81 273.9 0.0 1.9e-81 273.9 0.0 1.9 2 0 0 2 2 2 1 Histone deacetylase domain Brix PF04427.18 ETS79137.1 - 4.8e-38 131.2 0.0 6.9e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Brix domain RAMPs PF03787.15 ETS79137.1 - 0.0014 18.7 0.1 0.0017 18.4 0.1 1.1 1 0 0 1 1 1 1 RAMP superfamily Ras PF00071.22 ETS79138.1 - 5.9e-63 211.3 0.2 6.8e-63 211.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS79138.1 - 2.8e-35 121.1 0.2 3.9e-35 120.7 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS79138.1 - 5.7e-13 48.7 0.1 7.4e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ETS79138.1 - 8e-08 32.4 0.1 1.2e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ETS79138.1 - 0.00051 19.5 0.1 0.00074 18.9 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ETS79138.1 - 0.00051 19.6 0.1 0.0022 17.6 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ETS79138.1 - 0.00071 19.5 0.7 0.016 15.1 0.1 2.1 1 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 ETS79138.1 - 0.0025 18.1 0.1 0.013 15.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 ETS79138.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 ETS79138.1 - 0.017 15.2 0.1 0.044 13.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ETS79138.1 - 0.018 15.4 0.1 0.03 14.7 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 ETS79138.1 - 0.022 15.3 0.1 0.038 14.5 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 ETS79138.1 - 0.029 14.1 0.1 0.063 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 ETS79138.1 - 0.03 13.7 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 ETS79138.1 - 0.087 12.3 0.0 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.6 ETS79138.1 - 0.089 12.6 0.5 0.14 12.0 0.4 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SpoIIID PF12116.8 ETS79138.1 - 0.1 12.7 0.1 2 8.5 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D MCM PF00493.23 ETS79138.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 ETS79138.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Chromo PF00385.24 ETS79139.1 - 9.9e-08 31.8 0.1 2.1e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 ETS79139.1 - 0.04 14.1 0.0 0.088 13.0 0.0 1.6 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 DMT_6 PF04342.12 ETS79140.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative member of DMT superfamily (DUF486) DUF4050 PF13259.6 ETS79141.1 - 5.7e-56 189.7 0.0 5.7e-56 189.7 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF4050) DUF4452 PF14618.6 ETS79143.1 - 1.1e-79 266.2 14.8 1.6e-79 265.7 14.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Cyclin_N PF00134.23 ETS79144.1 - 7.1e-12 45.2 0.6 1.5e-11 44.2 0.6 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 ETS79144.1 - 0.0042 17.5 0.2 0.013 15.8 0.2 1.9 1 0 0 1 1 1 1 Cyclin C-terminal domain TFIIB PF00382.19 ETS79144.1 - 0.048 13.7 1.3 0.089 12.9 0.1 2.0 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Turandot PF07240.11 ETS79144.1 - 0.071 13.1 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Mito_carr PF00153.27 ETS79145.1 - 2.2e-64 213.4 5.4 1e-23 83.1 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 ETS79145.1 - 7.3e-21 72.1 5.2 3.1e-06 26.4 0.7 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 ETS79145.1 - 5.5e-20 71.6 3.4 2.9e-11 43.7 0.7 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 ETS79145.1 - 6.4e-19 66.5 6.1 2.6e-06 26.7 0.9 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 ETS79145.1 - 1.6e-17 61.9 7.7 3.1e-05 23.6 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 ETS79145.1 - 3e-10 39.8 3.7 0.00019 21.2 0.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ETS79145.1 - 1.4e-08 35.0 0.3 0.00053 20.3 0.0 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Atg29_N PF18388.1 ETS79145.1 - 0.069 13.0 0.5 0.18 11.6 0.5 1.6 1 0 0 1 1 1 0 Atg29 N-terminal domain Serine_protease PF18405.1 ETS79145.1 - 0.16 11.1 2.1 2.8 7.0 0.0 3.1 3 0 0 3 3 3 0 Gammaproteobacterial serine protease EF-hand_4 PF12763.7 ETS79145.1 - 1.8 8.6 4.7 16 5.5 0.0 3.5 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Peptidase_C48 PF02902.19 ETS79146.1 - 1.1e-18 67.9 0.3 2.7e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain KRAB PF01352.27 ETS79146.1 - 0.069 12.8 0.1 0.069 12.8 0.1 2.2 3 0 0 3 3 3 0 KRAB box FAD_binding_3 PF01494.19 ETS79147.1 - 5.4e-74 249.5 0.0 6.7e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 ETS79147.1 - 5.6e-40 137.1 0.0 9.3e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 ETS79147.1 - 0.0016 17.8 0.0 0.0048 16.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS79147.1 - 0.0018 18.8 0.0 0.0061 17.1 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS79147.1 - 0.0075 15.9 0.1 0.57 9.7 0.0 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS79147.1 - 0.015 15.5 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 ETS79147.1 - 0.018 14.6 0.4 0.047 13.3 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 ETS79147.1 - 0.064 12.0 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 ETS79147.1 - 0.087 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.21 ETS79147.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 ThiF family XdhC_C PF13478.6 ETS79147.1 - 0.15 12.6 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Rick_17kDa_Anti PF05433.15 ETS79150.1 - 0.011 15.5 12.7 0.011 15.5 12.7 3.2 2 1 0 2 2 2 0 Glycine zipper 2TM domain DUF3813 PF12758.7 ETS79150.1 - 0.18 12.2 0.1 0.43 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) DUF3824 PF12868.7 ETS79150.1 - 6.6 7.4 31.7 1.7 9.3 0.6 3.5 2 2 1 3 3 3 0 Domain of unknwon function (DUF3824) Mus7 PF09462.10 ETS79151.1 - 3.3e-126 422.6 0.2 4.8e-126 422.1 0.2 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family Dscam_C PF12355.8 ETS79151.1 - 0.14 13.2 7.5 3.6 8.6 3.5 3.0 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal SICA_C PF12879.7 ETS79151.1 - 0.21 11.6 4.9 7.4 6.6 0.0 3.4 4 0 0 4 4 4 0 SICA C-terminal inner membrane domain DDE_Tnp_IS240 PF13610.6 ETS79151.1 - 0.51 10.6 1.7 1.3 9.3 0.2 2.2 2 0 0 2 2 2 0 DDE domain adh_short_C2 PF13561.6 ETS79152.1 - 2.6e-09 37.0 0.3 1e-07 31.7 0.3 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS79152.1 - 4.2e-09 36.1 1.0 8.6e-08 31.9 1.0 2.7 1 1 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 ETS79152.1 - 0.021 14.2 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 ETS79152.1 - 0.031 13.5 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS79152.1 - 0.032 13.5 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 ETS79152.1 - 0.075 13.1 0.0 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 ETS79152.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GET2 PF08690.10 ETS79153.1 - 1.7e-43 149.5 0.0 3.1e-43 148.6 0.0 1.4 1 1 0 1 1 1 1 GET complex subunit GET2 Pex14_N PF04695.13 ETS79153.1 - 0.13 12.9 3.7 0.27 11.9 3.7 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med13_C PF06333.12 ETS79153.1 - 2.8 7.1 6.5 4.3 6.5 6.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Rrn6 PF10214.9 ETS79153.1 - 3.5 6.0 6.2 4.5 5.6 6.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TMEM135_C_rich PF15982.5 ETS79154.1 - 0.001 19.7 1.1 0.0046 17.6 1.1 2.1 1 1 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 DUF485 PF04341.12 ETS79154.1 - 0.0088 16.0 0.3 0.29 11.1 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function, DUF485 HLH PF00010.26 ETS79155.1 - 1.5e-10 40.8 0.4 4.6e-10 39.3 0.1 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CDC45 PF02724.14 ETS79155.1 - 0.39 9.0 8.6 0.51 8.6 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein OPT PF03169.15 ETS79156.1 - 1.4e-149 499.6 24.7 1.6e-149 499.4 24.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DNA_pol_B_thumb PF14791.6 ETS79157.1 - 0.0026 17.9 0.0 0.0068 16.5 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb Pentapeptide_2 PF01469.18 ETS79157.1 - 2.1 8.3 9.9 29 4.6 9.3 2.4 1 1 1 2 2 2 0 Pentapeptide repeats (8 copies) NAD_binding_10 PF13460.6 ETS79158.1 - 1.4e-08 34.8 0.0 2.1e-07 31.0 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS79158.1 - 5.3e-05 22.9 0.0 0.00026 20.6 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family Peripla_BP_6 PF13458.6 ETS79158.1 - 0.22 11.1 0.0 2 8.0 0.0 2.3 2 1 0 2 2 2 0 Periplasmic binding protein Glyco_hydro_32C PF08244.12 ETS79159.1 - 1.8e-24 86.5 1.4 3.2e-24 85.7 1.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 ETS79159.1 - 5.9e-15 55.6 0.1 1e-14 54.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Nitroreductase PF00881.24 ETS79161.1 - 1.8e-25 89.9 0.0 2.4e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ETS79161.1 - 4.1e-08 33.1 0.0 0.08 12.5 0.0 3.1 2 1 1 3 3 3 3 Putative TM nitroreductase Ribonuc_L-PSP PF01042.21 ETS79162.1 - 1.1e-12 48.1 0.0 1.3e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Tox-HNH-HHH PF15637.6 ETS79162.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif CD34_antigen PF06365.12 ETS79163.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Amnionless PF14828.6 ETS79163.1 - 0.047 12.5 0.1 0.06 12.2 0.1 1.1 1 0 0 1 1 1 0 Amnionless Yip1 PF04893.17 ETS79163.1 - 0.059 13.1 0.4 0.1 12.3 0.4 1.3 1 0 0 1 1 1 0 Yip1 domain Trp_oprn_chp PF09534.10 ETS79163.1 - 1.3 8.8 9.4 0.059 13.2 3.8 1.6 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Mucin PF01456.17 ETS79163.1 - 9.9 6.2 25.9 4.1 7.4 12.1 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Ank_2 PF12796.7 ETS79164.1 - 4.8e-49 164.9 1.0 1.3e-12 48.1 0.0 11.3 8 2 4 12 12 11 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS79164.1 - 5.1e-37 121.7 17.3 3.6e-06 26.9 0.0 16.3 18 0 0 18 18 17 7 Ankyrin repeat Ank_4 PF13637.6 ETS79164.1 - 4.9e-36 122.6 13.9 9.9e-09 35.6 0.1 12.1 9 2 5 14 14 13 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS79164.1 - 2.9e-32 110.3 18.6 5.3e-05 23.4 0.1 13.9 13 2 3 16 16 14 9 Ankyrin repeats (many copies) Ank PF00023.30 ETS79164.1 - 3.4e-31 106.3 14.2 7.4e-06 26.2 0.0 13.4 14 0 0 14 14 14 7 Ankyrin repeat NACHT PF05729.12 ETS79164.1 - 2.7e-08 33.9 0.0 6.7e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 ETS79164.1 - 9.1e-08 31.7 0.6 9.1e-08 31.7 0.6 1.8 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 ETS79164.1 - 0.0052 17.2 0.1 0.018 15.4 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS79164.1 - 0.0058 16.9 0.0 0.019 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ETS79164.1 - 0.06 13.8 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Syntaxin_2 PF14523.6 ETS79164.1 - 0.11 12.8 0.1 0.38 11.1 0.1 2.0 1 0 0 1 1 1 0 Syntaxin-like protein Ank_2 PF12796.7 ETS79165.1 - 3.4e-33 114.1 3.7 2.2e-10 41.0 0.1 5.2 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS79165.1 - 2.7e-21 73.4 7.4 2.2e-05 24.5 0.0 10.0 10 0 0 10 10 10 5 Ankyrin repeat Ank_4 PF13637.6 ETS79165.1 - 1.3e-18 67.1 3.1 5.1e-06 26.9 0.1 6.4 4 3 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 ETS79165.1 - 3.2e-14 52.6 17.1 0.0032 17.9 0.0 9.5 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 ETS79165.1 - 4.8e-11 42.7 2.7 0.0027 18.0 0.0 6.8 5 2 2 7 7 7 2 Ankyrin repeats (many copies) zf-C2H2_jaz PF12171.8 ETS79165.1 - 0.014 15.6 0.2 0.038 14.3 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 ETS79165.1 - 0.29 11.7 6.4 0.46 11.0 0.8 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS79165.1 - 1.2 10.2 4.7 12 7.1 0.2 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger Transferase PF02458.15 ETS79167.1 - 5.8e-11 41.7 0.0 7.7e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 Transferase family Rav1p_C PF12234.8 ETS79169.1 - 4.7e-280 930.5 0.3 5.8e-280 930.2 0.3 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal PQQ_2 PF13360.6 ETS79169.1 - 0.0014 18.2 0.4 0.045 13.3 0.1 2.5 2 0 0 2 2 2 1 PQQ-like domain PNP_phzG_C PF10590.9 ETS79169.1 - 0.0079 16.3 0.2 0.56 10.3 0.0 2.6 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region WD40 PF00400.32 ETS79169.1 - 0.32 11.9 5.5 15 6.6 0.1 5.4 6 0 0 6 6 6 0 WD domain, G-beta repeat Sfi1 PF08457.10 ETS79170.1 - 1.8e-28 99.4 96.8 6e-18 64.7 45.1 4.9 2 2 2 4 4 4 4 Sfi1 spindle body protein CX9C PF16860.5 ETS79171.1 - 0.0017 18.3 1.9 0.0023 17.9 1.9 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 ETS79171.1 - 0.0029 17.3 0.7 0.99 9.2 0.0 2.1 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.13 ETS79171.1 - 0.0039 17.3 3.7 0.02 15.0 3.3 1.9 1 1 1 2 2 2 1 CHCH domain tRNA-synt_1 PF00133.22 ETS79172.1 - 1.8e-220 733.3 0.2 2.8e-220 732.7 0.0 1.3 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ETS79172.1 - 8.4e-24 84.3 0.0 2.6e-23 82.7 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ETS79172.1 - 4.1e-16 58.7 0.1 9.3e-07 27.9 0.1 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 ETS79172.1 - 0.0075 15.6 0.0 0.093 12.1 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Mo25 PF08569.11 ETS79173.1 - 2.8e-128 427.9 0.5 3.2e-128 427.7 0.5 1.0 1 0 0 1 1 1 1 Mo25-like adh_short PF00106.25 ETS79174.1 - 1.4e-35 122.5 0.1 1.9e-35 122.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS79174.1 - 1.7e-26 93.2 0.0 2.2e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS79174.1 - 2.8e-05 24.1 0.1 5.2e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 ETS79174.1 - 0.024 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 ETS79174.1 - 0.068 12.6 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 ETS79174.1 - 0.17 11.7 0.0 1 9.2 0.0 2.3 4 0 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SWIB PF02201.18 ETS79175.1 - 8.7e-18 64.0 0.0 2.3e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 SWIB/MDM2 domain OrfB_IS605 PF01385.19 ETS79175.1 - 0.16 12.2 1.9 0.44 10.8 1.9 1.7 1 0 0 1 1 1 0 Probable transposase Pkinase PF00069.25 ETS79176.1 - 1.7e-68 230.8 0.0 2.4e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS79176.1 - 9.6e-34 116.8 0.0 5.8e-25 88.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ETS79176.1 - 3.3e-07 29.9 0.2 0.0042 16.4 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 ETS79176.1 - 0.0002 20.8 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ETS79176.1 - 0.00027 20.0 1.6 0.001 18.1 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 ETS79176.1 - 0.0074 16.2 0.0 0.021 14.7 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 ETS79176.1 - 0.045 13.4 0.1 3.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ANAPC_CDC26 PF10471.9 ETS79177.1 - 0.014 16.2 3.4 0.019 15.8 1.3 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Dscam_C PF12355.8 ETS79179.1 - 2.3 9.2 10.8 1.9 9.4 2.5 3.2 3 0 0 3 3 3 0 Down syndrome cell adhesion molecule C terminal GEN1_C PF18380.1 ETS79180.1 - 7.3e-28 97.5 0.4 4.1e-27 95.1 0.0 2.5 2 0 0 2 2 2 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 ETS79180.1 - 2e-25 89.0 0.0 4e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 ETS79180.1 - 3.1e-09 37.2 0.0 6.9e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Actin PF00022.19 ETS79181.1 - 3.1e-18 65.6 0.0 1.5e-08 33.7 0.0 3.1 3 0 0 3 3 3 3 Actin Gly_transf_sug PF04488.15 ETS79182.1 - 3.8e-13 49.9 0.0 7.9e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ETS79182.1 - 0.0058 16.1 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein tRNA-synt_2b PF00587.25 ETS79183.1 - 2.1e-20 73.5 0.0 3.3e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 ETS79183.1 - 5.9e-11 42.5 9.9 1.7e-10 41.1 9.9 1.7 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 ETS79183.1 - 0.13 12.8 8.1 0.26 11.8 8.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region RP-C PF03428.13 ETS79183.1 - 0.27 10.9 3.4 1.2 8.8 0.6 2.3 1 1 1 2 2 2 0 Replication protein C N-terminal domain DivIC PF04977.15 ETS79183.1 - 0.48 10.2 4.6 1.1 9.0 1.5 2.3 2 0 0 2 2 2 0 Septum formation initiator DNTTIP1_dimer PF18192.1 ETS79185.1 - 0.0083 16.5 0.2 4.8 7.6 0.1 4.0 2 0 0 2 2 2 1 DNTTIP1 dimerisation domain Lip_prot_lig_C PF10437.9 ETS79185.1 - 0.025 14.6 1.9 1.4 8.9 0.0 4.2 3 1 1 4 4 4 0 Bacterial lipoate protein ligase C-terminus HALZ PF02183.18 ETS79185.1 - 1.3 9.3 6.4 13 6.1 0.3 4.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Matrilin_ccoil PF10393.9 ETS79185.1 - 6.5 6.7 6.4 14 5.7 0.4 4.0 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin GMC_oxred_N PF00732.19 ETS79186.1 - 1.2e-29 103.6 0.0 2.2e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS79186.1 - 2.7e-17 63.6 0.0 5.1e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS79186.1 - 5.2e-06 25.8 3.5 0.00087 18.5 2.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ETS79186.1 - 0.00041 19.7 0.2 0.025 13.8 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS79186.1 - 0.00076 19.7 0.7 0.0021 18.2 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS79186.1 - 0.0037 16.6 0.4 1.2 8.3 0.7 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS79186.1 - 0.0099 14.6 0.2 0.016 14.0 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 ETS79186.1 - 0.019 14.2 0.2 0.029 13.6 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 ETS79186.1 - 0.043 12.9 0.1 0.071 12.1 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 ETS79186.1 - 0.052 12.6 0.1 0.085 11.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 ETS79186.1 - 0.059 13.9 0.7 1.5 9.4 0.7 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ETS79186.1 - 0.12 11.6 0.5 0.22 10.8 0.5 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 ETS79186.1 - 0.12 11.9 8.0 9.5 5.7 8.2 2.6 2 1 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 ETS79186.1 - 0.15 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Mito_carr PF00153.27 ETS79187.1 - 1.5e-29 101.8 0.7 9e-15 54.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_1 PF00561.20 ETS79188.1 - 2.8e-25 89.4 0.2 1.8e-20 73.7 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 ETS79188.1 - 4.9e-22 78.0 0.0 9e-22 77.1 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein MS_channel PF00924.18 ETS79189.1 - 8e-20 71.3 1.7 1.5e-19 70.4 1.7 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 ETS79189.1 - 0.0014 18.1 0.2 0.0044 16.5 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 ETS79189.1 - 0.0014 18.1 0.1 0.004 16.6 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 ETS79189.1 - 0.0019 18.6 0.0 0.0067 16.9 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair DUF1129 PF06570.11 ETS79189.1 - 0.083 12.4 2.4 1.7 8.1 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) EF-hand_6 PF13405.6 ETS79189.1 - 0.097 12.7 0.0 0.35 10.9 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain FtsH_ext PF06480.15 ETS79189.1 - 1.5 9.2 4.8 2.7 8.4 0.8 3.0 3 0 0 3 3 3 0 FtsH Extracellular Sugar_tr PF00083.24 ETS79190.1 - 1.8e-95 320.4 18.0 2.2e-95 320.2 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS79190.1 - 1.2e-15 57.3 39.9 1.9e-12 46.8 27.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abp2 PF09441.10 ETS79191.1 - 3.7e-82 274.5 0.0 5.3e-82 274.0 0.0 1.2 1 0 0 1 1 1 1 ARS binding protein 2 Mito_carr PF00153.27 ETS79192.1 - 2.4e-50 168.4 4.4 2.4e-17 62.6 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF2590 PF10761.9 ETS79192.1 - 0.066 13.4 0.0 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2590) Mak10 PF04112.13 ETS79193.1 - 1.4e-57 193.8 0.1 2.9e-57 192.9 0.1 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.13 ETS79194.1 - 3.6e-23 81.3 1.8 5.9e-23 80.6 1.8 1.4 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain PMBR PF09373.10 ETS79194.1 - 0.15 12.2 0.5 0.26 11.5 0.1 1.6 2 0 0 2 2 2 0 Pseudomurein-binding repeat Peptidase_M16_C PF05193.21 ETS79195.1 - 6.7e-13 49.1 0.0 1.1e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ETS79195.1 - 1.2e-10 41.6 0.1 3.6e-10 40.0 0.1 1.9 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) RNA_pol_Rpc82 PF05645.13 ETS79196.1 - 1.4e-41 142.9 0.0 1.3e-40 139.8 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 ETS79196.1 - 1.9e-14 53.5 1.0 3.5e-14 52.6 0.5 1.8 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 ETS79196.1 - 0.00014 21.7 0.3 0.016 15.0 0.0 2.7 2 1 0 2 2 2 2 TFIIE alpha subunit Methyltransf_25 PF13649.6 ETS79197.1 - 1.5e-13 51.2 0.0 5.2e-13 49.5 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS79197.1 - 3.3e-11 43.7 0.0 1.8e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS79197.1 - 2.4e-10 40.4 0.0 5.6e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ETS79197.1 - 1.5e-09 37.7 0.1 5.1e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 ETS79197.1 - 1.2e-07 31.8 0.0 2.8e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ETS79197.1 - 1.6e-05 24.4 0.0 4.3e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 ETS79197.1 - 1.9e-05 24.6 0.1 3.6e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS79197.1 - 0.00013 21.6 0.1 0.00022 20.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 ETS79197.1 - 0.00022 21.9 0.0 0.00065 20.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ETS79197.1 - 0.00072 18.9 0.1 0.002 17.4 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_16 PF10294.9 ETS79197.1 - 0.0016 18.2 0.0 0.0039 16.9 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 ETS79197.1 - 0.002 17.5 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 ETS79197.1 - 0.0031 17.7 0.0 0.0082 16.3 0.0 1.7 2 0 0 2 2 1 1 FtsJ-like methyltransferase PCMT PF01135.19 ETS79197.1 - 0.0034 17.2 0.1 0.0057 16.4 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 ETS79197.1 - 0.0039 18.2 0.1 0.032 15.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 ETS79197.1 - 0.017 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) UPF0242 PF06785.11 ETS79197.1 - 0.048 13.8 0.1 0.085 13.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus UPF0020 PF01170.18 ETS79197.1 - 0.056 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 HalX PF08663.10 ETS79197.1 - 0.066 13.5 2.3 0.15 12.4 2.3 1.6 1 0 0 1 1 1 0 HalX domain TehB PF03848.14 ETS79197.1 - 0.11 12.0 0.0 0.27 10.6 0.0 1.7 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 ETS79197.1 - 0.14 12.1 0.6 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MetW PF07021.12 ETS79197.1 - 0.17 11.5 0.3 0.49 9.9 0.0 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Surfac_D-trimer PF09006.11 ETS79197.1 - 0.19 11.6 0.0 5.5 7.0 0.1 2.7 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Uso1_p115_head PF04869.14 ETS79198.1 - 5.4e-103 344.4 0.0 1.4e-102 343.0 0.0 1.8 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 ETS79198.1 - 3.7e-19 69.3 39.9 3.7e-19 69.3 39.9 8.0 1 1 7 8 8 8 1 Uso1 / p115 like vesicle tethering protein, C terminal region XRN_M PF17846.1 ETS79199.1 - 3.4e-142 474.5 0.0 8.3e-142 473.2 0.0 1.6 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 ETS79199.1 - 2.3e-98 328.5 0.8 2.3e-98 328.5 0.0 1.4 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 ETS79199.1 - 0.00082 19.3 1.8 0.0017 18.4 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 ETS79199.1 - 0.031 14.1 1.1 0.082 12.7 1.1 1.7 1 0 0 1 1 1 0 Zinc knuckle RasGAP PF00616.19 ETS79200.1 - 2.6e-33 115.5 0.3 5.2e-30 104.7 0.3 2.5 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 ETS79200.1 - 2.5e-08 34.2 0.0 6.8e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 ETS79200.1 - 0.014 15.3 1.0 0.049 13.5 0.2 2.5 2 0 0 2 2 2 0 Cell morphogenesis C-terminal NAD_binding_10 PF13460.6 ETS79201.1 - 0.00058 19.8 1.7 0.00067 19.6 1.7 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Trp_repressor PF01371.19 ETS79201.1 - 0.01 15.9 0.1 0.014 15.5 0.1 1.2 1 0 0 1 1 1 0 Trp repressor protein Rhabdo_ncap PF00945.18 ETS79201.1 - 0.041 12.8 0.0 0.043 12.7 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF3433 PF11915.8 ETS79203.1 - 2e-20 73.0 18.5 2.8e-12 46.9 1.2 4.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) DUF3267 PF11667.8 ETS79203.1 - 0.19 12.0 0.0 0.19 12.0 0.0 3.4 4 0 0 4 4 4 0 Putative zincin peptidase PRR18 PF15671.5 ETS79204.1 - 3.1 7.6 13.1 5.5 6.8 13.1 1.3 1 0 0 1 1 1 0 Proline-rich protein family 18 JmjC PF02373.22 ETS79205.1 - 9.4e-10 38.9 0.3 3.9e-09 37.0 0.3 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 ETS79205.1 - 1.4e-08 34.9 10.8 1.4e-08 34.9 10.8 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 ETS79205.1 - 0.04 13.6 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 Cupin domain UbiA PF01040.18 ETS79206.1 - 5.6e-43 147.1 20.9 7.2e-43 146.7 20.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosom_S12_S23 PF00164.25 ETS79207.1 - 3.8e-51 171.5 0.6 4.7e-51 171.2 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF5315 PF17242.2 ETS79208.1 - 7.2e-29 99.4 0.5 1.7e-28 98.2 0.5 1.6 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) Tk-SP_N-pro PF18237.1 ETS79209.1 - 0.026 14.6 0.3 0.061 13.4 0.2 1.6 1 1 1 2 2 2 0 Tk-SP N-propeptide domain Inhibitor_I9 PF05922.16 ETS79209.1 - 0.033 14.9 0.1 0.053 14.2 0.1 1.5 1 1 0 1 1 1 0 Peptidase inhibitor I9 Ntox27 PF15531.6 ETS79209.1 - 0.078 12.9 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 Bacterial toxin 27 HdeA PF06411.11 ETS79209.1 - 0.16 12.2 1.3 9.8 6.4 0.2 2.2 2 0 0 2 2 2 0 HdeA/HdeB family CCDC92 PF14916.6 ETS79210.1 - 0.0051 16.5 1.4 0.0051 16.5 1.4 6.7 5 2 2 7 7 7 1 Coiled-coil domain of unknown function KASH_CCD PF14662.6 ETS79210.1 - 0.0084 16.0 11.5 0.0084 16.0 11.5 6.2 3 1 3 6 6 6 2 Coiled-coil region of CCDC155 or KASH DUF641 PF04859.12 ETS79210.1 - 0.011 16.1 8.0 0.011 16.1 8.0 6.5 4 3 3 7 7 7 0 Plant protein of unknown function (DUF641) HOOK PF05622.12 ETS79210.1 - 0.075 11.2 84.0 0.3 9.2 22.9 2.8 1 1 1 2 2 2 0 HOOK protein E3_UbLigase_EDD PF11547.8 ETS79210.1 - 0.076 12.7 2.5 8 6.2 0.0 4.3 4 0 0 4 4 4 0 E3 ubiquitin ligase EDD Myc-LZ PF02344.15 ETS79210.1 - 0.43 10.7 16.0 0.44 10.7 2.6 4.8 3 0 0 3 3 3 0 Myc leucine zipper domain SUV3_C PF12513.8 ETS79210.1 - 0.81 9.7 0.0 0.81 9.7 0.0 3.4 4 0 0 4 4 4 0 Mitochondrial degradasome RNA helicase subunit C terminal DUF4845 PF16137.5 ETS79210.1 - 1.1 10.1 4.8 30 5.6 0.2 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4845) DASH_Dam1 PF08653.10 ETS79210.1 - 4.2 7.2 5.2 20 5.1 0.2 4.6 3 1 0 3 3 3 0 DASH complex subunit Dam1 MitMem_reg PF13012.6 ETS79211.1 - 2.1e-37 128.0 0.1 3.7e-37 127.2 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 ETS79211.1 - 4.6e-32 110.5 0.0 9.3e-32 109.5 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 ETS79211.1 - 0.079 12.6 1.4 0.12 12.1 1.4 1.3 1 0 0 1 1 1 0 Possible tRNA binding domain ADK PF00406.22 ETS79212.1 - 4.6e-58 195.6 0.0 6.3e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ETS79212.1 - 4e-22 79.1 0.0 8.1e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 ETS79212.1 - 2.2e-17 62.8 0.0 5e-17 61.6 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 ETS79212.1 - 0.0001 22.5 0.0 0.0002 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETS79212.1 - 0.00031 21.3 0.0 0.00099 19.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain Coprogen_oxidas PF01218.18 ETS79214.1 - 3.3e-141 469.2 0.3 4.9e-141 468.7 0.1 1.4 2 0 0 2 2 2 1 Coproporphyrinogen III oxidase CRISPR_Cse2 PF09485.10 ETS79214.1 - 0.021 15.4 1.2 0.039 14.5 1.2 1.4 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) SMP PF04927.12 ETS79215.1 - 0.66 10.5 11.5 0.25 11.9 8.8 1.7 1 1 0 1 1 1 0 Seed maturation protein Fungal_trans PF04082.18 ETS79216.1 - 1.4e-07 30.9 2.1 2.5e-07 30.0 2.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain VWA_3_C PF18571.1 ETS79216.1 - 0.11 12.4 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain F-box PF00646.33 ETS79218.1 - 0.00029 20.7 0.2 0.00088 19.1 0.1 1.9 2 0 0 2 2 2 1 F-box domain DUF5376 PF17346.2 ETS79218.1 - 0.019 15.3 0.1 0.11 12.8 0.0 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5376) F-box-like PF12937.7 ETS79218.1 - 0.082 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.16 ETS79219.1 - 2.8e-18 66.0 38.3 5.8e-15 55.1 28.2 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily MAGI_u1 PF16663.5 ETS79219.1 - 0.015 15.3 1.8 0.042 13.9 0.1 2.3 2 0 0 2 2 2 0 Unstructured region on MAGI Nodulin-like PF06813.13 ETS79219.1 - 0.076 12.5 6.6 0.26 10.7 6.6 1.9 1 1 0 1 1 1 0 Nodulin-like 7tm_7 PF08395.12 ETS79219.1 - 0.12 11.6 1.2 3.9 6.6 0.1 2.3 2 0 0 2 2 2 0 7tm Chemosensory receptor COesterase PF00135.28 ETS79220.1 - 2.7e-78 264.1 0.0 3.5e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS79220.1 - 0.00034 20.5 0.6 0.0039 17.1 0.6 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_75 PF07335.11 ETS79221.1 - 3.5e-39 134.7 0.0 3.5e-39 134.7 0.0 1.6 2 0 0 2 2 2 1 Fungal chitosanase of glycosyl hydrolase group 75 Ala_racemase_N PF01168.20 ETS79222.1 - 2.6e-20 73.0 0.0 3.3e-20 72.7 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain zf-HIT PF04438.16 ETS79223.1 - 8.7e-10 38.3 9.2 1.3e-09 37.7 9.2 1.3 1 0 0 1 1 1 1 HIT zinc finger Ribosomal_S7e PF01251.18 ETS79223.1 - 0.03 14.1 0.1 0.053 13.3 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S7e LSM14 PF12701.7 ETS79224.1 - 1.5e-31 108.3 0.1 2.3e-31 107.7 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 ETS79224.1 - 9e-19 68.3 0.4 2.6e-18 66.8 0.4 1.8 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.6 ETS79224.1 - 1.9e-07 31.1 0.1 5.2e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Ataxin 2 SM domain DUF2564 PF10819.8 ETS79224.1 - 0.88 10.0 4.1 1.4 9.4 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) DUF3138 PF11336.8 ETS79224.1 - 1.3 7.6 8.4 1.9 7.0 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Clr5 PF14420.6 ETS79226.1 - 1.7e-05 24.9 0.3 5.2e-05 23.4 0.3 1.9 1 0 0 1 1 1 1 Clr5 domain Hydrolase_4 PF12146.8 ETS79227.1 - 0.0043 16.3 0.0 0.0089 15.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Tcf25 PF04910.14 ETS79228.1 - 3.7e-57 194.0 0.0 7.4e-57 193.0 0.0 1.5 1 0 0 1 1 1 1 Transcriptional repressor TCF25 CDC45 PF02724.14 ETS79228.1 - 5.6 5.1 17.9 5.3 5.2 13.0 2.3 2 0 0 2 2 2 0 CDC45-like protein HMA PF00403.26 ETS79229.1 - 3e-16 59.6 1.4 3.1e-16 59.6 0.6 1.4 2 0 0 2 2 2 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 ETS79229.1 - 0.094 13.1 0.1 0.47 10.8 0.0 1.9 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Phosphoesterase PF04185.14 ETS79230.1 - 2.3e-23 83.0 0.2 2.3e-22 79.7 0.2 2.0 1 1 0 1 1 1 1 Phosphoesterase family Fungal_trans PF04082.18 ETS79231.1 - 2.4e-12 46.5 0.2 3.6e-12 45.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS79231.1 - 3.7e-07 30.1 7.9 8.3e-07 29.0 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain cwf21 PF08312.12 ETS79231.1 - 0.077 13.2 0.0 0.26 11.5 0.0 1.9 1 0 0 1 1 1 0 cwf21 domain Thiolase_N PF00108.23 ETS79232.1 - 3.2e-15 56.2 0.1 8.1e-14 51.6 0.0 2.5 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ETS79232.1 - 3.2e-12 46.2 0.2 1.1e-11 44.4 0.2 1.9 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 ETS79232.1 - 0.00031 20.5 0.2 0.018 14.9 0.2 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 ETS79232.1 - 0.0016 17.2 0.6 0.039 12.7 0.1 2.7 3 0 0 3 3 3 1 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 ETS79232.1 - 0.0046 16.6 0.3 0.015 14.8 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ETS79232.1 - 0.035 14.1 1.2 1.1 9.3 0.0 2.8 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain DUF2070 PF09843.9 ETS79233.1 - 0.0071 14.7 3.0 0.0088 14.4 3.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) DUF2231 PF09990.9 ETS79233.1 - 0.89 10.0 6.6 0.17 12.3 1.4 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Sugar_tr PF00083.24 ETS79235.1 - 4.9e-82 276.2 19.7 5.5e-82 276.0 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS79235.1 - 2.9e-10 39.6 39.8 2.7e-09 36.4 36.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Jagunal PF07086.12 ETS79235.1 - 2.1 8.4 4.6 1.9 8.5 0.3 2.6 3 0 0 3 3 3 0 Jagunal, ER re-organisation during oogenesis Fungal_trans PF04082.18 ETS79236.1 - 2.5e-18 66.1 0.1 4.2e-18 65.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS79236.1 - 7.7e-08 32.3 12.4 1.9e-07 31.1 12.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thr_synth_N PF14821.6 ETS79238.1 - 7.1e-28 96.6 0.0 1.6e-27 95.5 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 ETS79238.1 - 2e-18 66.8 0.0 8.7e-18 64.7 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MIP PF00230.20 ETS79239.1 - 2.6e-49 168.0 13.2 3.4e-49 167.6 13.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein Transgly_assoc PF04226.13 ETS79239.1 - 3.9 7.8 10.7 1.1 9.5 0.7 3.1 3 0 0 3 3 3 0 Transglycosylase associated protein Methyltransf_11 PF08241.12 ETS79241.1 - 4.1e-10 40.2 0.0 1e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS79241.1 - 3.9e-08 33.3 0.0 9.3e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS79241.1 - 1.4e-07 32.2 0.0 2.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS79241.1 - 1.7e-07 31.8 0.1 7.4e-07 29.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS79241.1 - 0.00016 21.5 0.0 0.00053 19.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS79241.1 - 0.023 14.0 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Adaptin_N PF01602.20 ETS79242.1 - 3.3e-120 402.1 4.3 4e-120 401.8 4.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 ETS79242.1 - 8.6e-47 158.0 0.0 2.2e-46 156.7 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 ETS79242.1 - 1.1e-16 61.1 0.0 2.3e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 ETS79242.1 - 0.0019 18.3 0.4 0.22 11.6 0.0 2.9 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 P16-Arc PF04699.14 ETS79245.1 - 1.8e-50 171.2 0.0 2.2e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) CN_hydrolase PF00795.22 ETS79246.1 - 3.2e-38 131.6 0.2 1.2e-37 129.7 0.2 1.8 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase FIT1_2 PF17357.2 ETS79246.1 - 0.21 11.7 1.4 0.41 10.8 1.4 1.5 1 0 0 1 1 1 0 Facilitor Of iron transport 1 and 2 FAD_binding_4 PF01565.23 ETS79247.1 - 3.3e-19 69.0 0.4 5.7e-19 68.2 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS79247.1 - 5.1e-05 23.3 0.0 0.00015 21.8 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like RabGAP-TBC PF00566.18 ETS79248.1 - 4.9e-46 157.1 0.1 1.1e-45 155.9 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Fungal_trans PF04082.18 ETS79251.1 - 1.2e-21 76.9 0.0 2.2e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS79251.1 - 7.3e-08 32.4 13.7 1.4e-07 31.5 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AIG1 PF04548.16 ETS79251.1 - 0.0084 15.5 2.2 1.4 8.1 0.0 2.7 3 0 0 3 3 3 2 AIG1 family DUF5094 PF17015.5 ETS79251.1 - 1.1 9.3 3.0 1.8 8.6 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) PRKG1_interact PF15898.5 ETS79251.1 - 1.5 9.8 7.3 2.6 9.0 7.3 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain A_deaminase PF00962.22 ETS79252.1 - 2.9e-73 247.1 0.0 3.3e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF2063 PF09836.9 ETS79252.1 - 0.0033 17.6 0.1 0.0064 16.7 0.1 1.5 1 0 0 1 1 1 1 Putative DNA-binding domain Amidohydro_1 PF01979.20 ETS79252.1 - 0.035 13.4 0.0 0.36 10.1 0.0 2.1 1 1 0 1 1 1 0 Amidohydrolase family Pyridoxal_deC PF00282.19 ETS79253.1 - 2.1e-79 266.9 0.0 2.9e-79 266.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 ETS79253.1 - 5.8e-07 28.8 0.0 3.9e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Abhydrolase_3 PF07859.13 ETS79254.1 - 2.9e-34 118.8 0.0 1.9e-23 83.4 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS79254.1 - 0.037 12.9 0.0 0.058 12.3 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Lipase_3 PF01764.25 ETS79254.1 - 0.058 13.3 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Aminotran_3 PF00202.21 ETS79255.1 - 2.2e-112 375.7 0.0 2.9e-112 375.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ETS79255.1 - 2.9e-05 23.4 0.0 6.5e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Cutinase PF01083.22 ETS79256.1 - 1e-50 172.2 2.9 1.2e-50 172.0 2.9 1.0 1 0 0 1 1 1 1 Cutinase Thioesterase PF00975.20 ETS79256.1 - 0.0012 19.0 0.1 0.0018 18.4 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain PE-PPE PF08237.11 ETS79256.1 - 0.0017 17.9 0.4 0.0024 17.5 0.4 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.20 ETS79256.1 - 0.0023 17.6 0.0 0.0029 17.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold VirJ PF06057.11 ETS79256.1 - 0.0032 17.4 0.0 0.0046 16.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 ETS79256.1 - 0.0065 16.1 0.1 0.01 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 ETS79256.1 - 0.0097 15.8 0.6 0.015 15.1 0.2 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 ETS79256.1 - 0.015 15.2 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Palm_thioest PF02089.15 ETS79256.1 - 0.028 14.2 0.1 0.029 14.2 0.1 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 ETS79256.1 - 0.071 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 GMC_oxred_C PF05199.13 ETS79257.1 - 4.4e-33 114.8 0.0 7.8e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 ETS79257.1 - 2.9e-28 99.1 0.0 3.9e-25 88.8 0.0 2.4 2 1 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS79257.1 - 2.9e-06 26.6 0.0 0.00021 20.5 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS79257.1 - 5.5e-06 25.8 0.0 6.8e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS79257.1 - 0.00051 20.2 0.1 0.0012 19.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS79257.1 - 0.00059 19.2 0.1 0.66 9.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS79257.1 - 0.004 16.8 0.1 0.047 13.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ETS79257.1 - 0.0058 15.9 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ETS79257.1 - 0.0069 15.5 0.3 0.01 14.9 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 ETS79257.1 - 0.015 14.6 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS79257.1 - 0.018 13.8 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 ETS79257.1 - 0.095 11.8 0.1 0.34 10.0 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A SDA1 PF05285.12 ETS79258.1 - 9.1e-87 291.7 68.5 2e-84 284.0 61.7 3.1 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 ETS79258.1 - 4.4e-19 68.5 0.0 1.3e-18 67.1 0.0 1.9 1 0 0 1 1 1 1 NUC130/3NT domain Dict-STAT-coil PF09267.10 ETS79258.1 - 0.015 15.6 0.2 0.077 13.4 0.2 2.2 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil Beta-TrCP_D PF12125.8 ETS79260.1 - 0.0063 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 D domain of beta-TrCP Dioxygenase_C PF00775.21 ETS79261.1 - 3.9e-11 42.7 0.1 5.7e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase Alpha-amylase PF00128.24 ETS79263.1 - 7.9e-23 81.5 2.0 4.3e-22 79.1 2.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 ETS79263.1 - 9.8e-10 37.3 0.1 0.021 13.1 0.1 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 ETS79263.1 - 0.018 15.2 0.3 0.061 13.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1939) Kin17_mid PF10357.9 ETS79263.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein bZIP_1 PF00170.21 ETS79265.1 - 4.2e-09 36.4 10.3 1.4e-08 34.7 10.3 2.0 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ETS79265.1 - 0.0017 18.4 10.9 0.0017 18.4 10.9 2.8 2 0 0 2 2 2 1 Basic region leucine zipper Endonuc_Holl PF10107.9 ETS79265.1 - 5.1 6.9 7.9 1.1 9.1 0.5 2.5 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase DivIC PF04977.15 ETS79265.1 - 9.3 6.1 23.5 0.22 11.3 0.9 3.4 3 0 0 3 3 3 0 Septum formation initiator YabA PF06156.13 ETS79265.1 - 9.8 6.9 7.6 2.6 8.8 0.2 3.0 3 0 0 3 3 3 0 Initiation control protein YabA DUF3533 PF12051.8 ETS79266.1 - 1.5e-115 386.1 16.6 1.7e-115 385.9 16.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Macoilin PF09726.9 ETS79266.1 - 8 4.9 7.8 11 4.4 7.8 1.1 1 0 0 1 1 1 0 Macoilin family Mannosidase_ig PF17786.1 ETS79267.1 - 3.2e-17 62.9 0.1 1.1e-16 61.2 0.0 2.0 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 ETS79267.1 - 5e-05 23.9 0.0 0.00062 20.4 0.0 2.6 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 ETS79267.1 - 0.0012 18.1 0.1 0.0045 16.1 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cytotoxic PF09000.10 ETS79267.1 - 0.092 13.1 0.2 0.53 10.7 0.1 2.1 2 0 0 2 2 2 0 Cytotoxic MFS_1 PF07690.16 ETS79268.1 - 1.2e-32 113.3 39.7 2.2e-28 99.2 24.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 ETS79269.1 - 4.7e-10 40.0 5.5 4.8e-08 33.5 0.1 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) F-box PF00646.33 ETS79270.1 - 0.0013 18.5 0.1 0.004 17.0 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ETS79270.1 - 0.013 15.3 2.2 0.014 15.3 0.3 1.9 2 0 0 2 2 2 0 F-box-like FAD_binding_3 PF01494.19 ETS79271.1 - 7.8e-22 78.0 0.0 7.3e-21 74.8 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ETS79271.1 - 0.00011 21.5 0.2 0.15 11.3 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS79271.1 - 0.0003 20.0 0.1 0.21 10.6 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ETS79271.1 - 0.00048 19.5 1.2 0.15 11.3 0.1 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ETS79271.1 - 0.0013 18.1 0.0 0.011 15.0 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ETS79271.1 - 0.0055 16.9 0.0 0.028 14.7 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ETS79271.1 - 0.047 14.2 0.4 0.61 10.7 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS79271.1 - 0.092 12.7 0.6 0.6 10.1 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 ETS79271.1 - 0.13 11.1 1.3 1.3 7.8 0.2 2.2 1 1 0 2 2 2 0 Tryptophan halogenase Cutinase PF01083.22 ETS79272.1 - 3.1e-41 141.3 1.4 3.5e-41 141.1 1.4 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 ETS79272.1 - 5.5e-05 23.1 0.0 7.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 ETS79272.1 - 0.0011 18.6 0.1 0.0015 18.1 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.8 ETS79272.1 - 0.013 15.1 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) HpcH_HpaI PF03328.14 ETS79273.1 - 6.5e-24 84.3 0.4 8.7e-24 83.9 0.4 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family MFS_1 PF07690.16 ETS79274.1 - 5.2e-31 107.9 25.9 5.2e-31 107.9 25.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS79274.1 - 0.00081 18.3 0.3 0.00081 18.3 0.3 2.2 2 1 0 3 3 3 1 MFS_1 like family PD40 PF07676.12 ETS79275.1 - 1.3e-38 130.1 26.7 1.8e-06 27.7 0.3 9.5 9 0 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 ETS79275.1 - 6.9e-11 41.5 0.4 0.16 10.7 0.0 6.1 5 1 0 5 5 5 4 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9_N PF02897.15 ETS79275.1 - 0.065 12.0 0.8 2.6 6.7 0.1 3.1 3 1 0 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Proteasome_A_N PF10584.9 ETS79275.1 - 5.6 6.7 15.1 75 3.1 0.0 6.8 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature Methyltransf_23 PF13489.6 ETS79276.1 - 6.8e-12 45.5 0.0 9.7e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS79276.1 - 1.8e-11 44.5 0.0 3.2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS79276.1 - 9.5e-10 39.1 0.0 1.6e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS79276.1 - 1.7e-07 31.2 0.0 3.2e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS79276.1 - 4.2e-07 30.6 0.0 7.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 ETS79276.1 - 0.015 14.2 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 ETS79276.1 - 0.063 12.6 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DGF-1_C PF11040.8 ETS79276.1 - 0.17 11.9 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus SKG6 PF08693.10 ETS79277.1 - 0.0016 17.8 0.1 0.0037 16.6 0.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.7 ETS79277.1 - 0.027 13.9 0.1 0.046 13.2 0.1 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Spore_YtfJ PF09579.10 ETS79277.1 - 0.2 11.8 1.7 0.55 10.4 1.7 1.7 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) Granulin PF00396.18 ETS79277.1 - 0.4 11.0 5.0 0.68 10.3 1.0 2.5 2 0 0 2 2 2 0 Granulin Mid2 PF04478.12 ETS79277.1 - 0.42 10.4 0.1 0.42 10.4 0.1 2.3 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Ank_5 PF13857.6 ETS79279.1 - 5e-09 36.2 0.0 2.7e-06 27.5 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS79279.1 - 1.2e-08 35.3 0.0 0.0049 17.4 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS79279.1 - 2.8e-07 31.0 0.0 0.0064 17.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS79279.1 - 8.7e-06 25.7 0.0 0.13 12.9 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 ETS79279.1 - 0.0026 18.1 0.3 0.027 14.9 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat FRB_dom PF08771.11 ETS79279.1 - 1.1 9.7 4.5 1.5 9.3 1.2 2.7 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain adh_short_C2 PF13561.6 ETS79280.1 - 8.6e-54 182.6 0.1 1e-53 182.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS79280.1 - 7.2e-37 126.7 0.1 8.5e-37 126.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS79280.1 - 4.5e-06 26.7 0.3 6.6e-06 26.2 0.3 1.2 1 0 0 1 1 1 1 KR domain Glyco_hydro_3_C PF01915.22 ETS79281.1 - 1.4e-64 217.8 0.0 4e-64 216.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS79281.1 - 5e-48 164.1 0.0 1.1e-47 163.0 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS79281.1 - 2.2e-18 66.1 1.1 4.8e-18 65.0 1.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 ETS79281.1 - 9.7e-18 64.4 0.2 1.6e-17 63.6 0.2 1.3 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 ETS79281.1 - 0.0041 17.5 1.3 0.0095 16.3 0.4 2.1 2 0 0 2 2 2 1 GLEYA domain MFS_1 PF07690.16 ETS79282.1 - 4.4e-47 160.7 37.9 4.4e-47 160.7 37.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS79282.1 - 6.8e-13 48.3 7.5 6.8e-13 48.3 7.5 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 ETS79282.1 - 8.9e-07 28.5 12.8 2.9e-05 23.5 4.1 2.3 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 ETS79282.1 - 6.9e-06 24.8 1.4 6.9e-06 24.8 1.4 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 ETS79282.1 - 0.0002 19.8 12.3 0.0051 15.2 0.8 3.3 3 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Peptidase_M20 PF01546.28 ETS79283.1 - 1.5e-12 47.7 0.7 2.3e-12 47.1 0.7 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ETS79283.1 - 1.6e-06 28.0 1.4 4.6e-06 26.5 0.4 2.3 2 1 0 2 2 2 1 Peptidase dimerisation domain MFS_1 PF07690.16 ETS79284.1 - 6.5e-38 130.6 31.8 6.5e-38 130.6 31.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS79284.1 - 1.2e-09 37.9 20.7 2.7e-09 36.8 5.4 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MASE3 PF17159.4 ETS79284.1 - 0.0006 19.5 5.9 0.0006 19.5 5.9 2.9 2 2 1 3 3 3 1 Membrane-associated sensor domain DUF2985 PF11204.8 ETS79284.1 - 0.59 10.3 4.8 1 9.5 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2985) Cu-oxidase_2 PF07731.14 ETS79286.1 - 7.1e-49 165.1 8.6 4.6e-45 152.7 0.9 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ETS79286.1 - 1.4e-41 141.3 6.9 5.1e-38 129.8 2.3 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 ETS79286.1 - 3.5e-38 131.2 3.9 4.8e-36 124.3 0.6 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.6 ETS79286.1 - 0.015 15.4 0.0 2.4 8.3 0.0 3.3 3 1 1 4 4 4 0 Cupredoxin-like domain FTR1 PF03239.14 ETS79287.1 - 4.3e-85 285.6 9.1 5.3e-85 285.3 9.1 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Rft-1 PF04506.13 ETS79287.1 - 0.0051 15.6 0.6 0.0083 14.9 0.6 1.3 1 0 0 1 1 1 1 Rft protein Phage_holin_3_6 PF07332.11 ETS79287.1 - 0.01 15.8 3.6 0.01 15.8 3.6 2.7 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Ferric_reduct PF01794.19 ETS79288.1 - 5.7e-20 71.7 10.0 5.7e-20 71.7 10.0 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ETS79288.1 - 1.8e-15 57.4 0.0 3.6e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ETS79288.1 - 3e-13 49.8 0.0 6.4e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 ETS79288.1 - 0.00017 22.2 0.0 0.0091 16.6 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain MBOAT_2 PF13813.6 ETS79289.1 - 0.0031 17.7 1.3 0.0064 16.7 0.9 1.6 1 1 1 2 2 2 1 Membrane bound O-acyl transferase family p450 PF00067.22 ETS79291.1 - 1.6e-45 155.7 0.0 2e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 ETS79292.1 - 1.3e-20 73.7 0.0 1.8e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain p450 PF00067.22 ETS79293.1 - 1.7e-23 83.1 0.0 4.4e-23 81.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS79294.1 - 6.3e-07 28.5 0.0 7.2e-07 28.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS79295.1 - 1.7e-25 89.7 0.0 1.8e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.25 ETS79296.1 - 1.5e-06 28.4 0.0 1.9e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS79296.1 - 1.8e-05 25.1 0.0 2.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS79296.1 - 0.00011 22.2 0.0 0.00016 21.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase PF00903.25 ETS79296.1 - 0.0015 18.7 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TPR_7 PF13176.6 ETS79296.1 - 0.073 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat F-box-like PF12937.7 ETS79297.1 - 0.027 14.3 0.8 0.1 12.5 0.8 2.1 1 0 0 1 1 1 0 F-box-like p450 PF00067.22 ETS79298.1 - 3.5e-63 214.0 0.0 4.3e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Myf5 PF12232.8 ETS79299.1 - 0.15 12.8 4.2 0.29 11.9 4.2 1.4 1 0 0 1 1 1 0 Myogenic determination factor 5 DUF3759 PF12585.8 ETS79300.1 - 2.2e-40 136.6 9.4 2.5e-40 136.4 9.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Dioxygenase_C PF00775.21 ETS79301.1 - 2.8e-05 23.6 0.0 4.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase SpaA PF17802.1 ETS79301.1 - 0.39 11.1 4.0 0.27 11.6 0.2 2.5 3 0 0 3 3 3 0 Prealbumin-like fold domain Glyco_hydro_3_C PF01915.22 ETS79302.1 - 1.5e-62 211.2 0.0 2.3e-62 210.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS79302.1 - 3e-50 171.4 0.0 8.6e-50 169.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS79302.1 - 2.5e-17 62.8 0.2 4.9e-17 61.8 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 ETS79302.1 - 1.1e-12 48.0 0.0 2e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Sugar_tr PF00083.24 ETS79303.1 - 3.2e-87 293.3 25.2 3.8e-87 293.0 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS79303.1 - 1e-22 80.5 19.6 1e-22 80.5 19.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily PUCC PF03209.15 ETS79303.1 - 0.063 12.3 13.8 0.027 13.5 6.2 2.2 2 0 0 2 2 2 0 PUCC protein DUF2754 PF10953.8 ETS79303.1 - 0.21 11.8 2.9 0.97 9.7 2.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) TssN PF17555.2 ETS79303.1 - 4.1 6.7 8.6 9.2 5.6 8.6 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssN Sugar_tr PF00083.24 ETS79304.1 - 3.5e-108 362.4 17.8 3.9e-108 362.2 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS79304.1 - 4.5e-29 101.5 46.8 7.2e-24 84.4 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 ETS79305.1 - 1.2e-13 50.6 6.4 2.4e-13 49.7 6.4 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS79305.1 - 3.4e-07 30.3 12.6 6.9e-07 29.3 12.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 ETS79306.1 - 6.1e-51 173.2 0.9 8.8e-51 172.7 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS79306.1 - 2.8e-39 134.6 1.3 3.3e-39 134.4 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS79306.1 - 3.9e-09 36.7 0.8 5.6e-09 36.2 0.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS79306.1 - 0.0015 18.0 0.2 0.81 9.1 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 ETS79306.1 - 0.089 12.7 0.8 0.31 10.9 0.2 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Transketolase_N PF00456.21 ETS79307.1 - 5.4e-130 433.2 0.0 8.9e-130 432.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ETS79307.1 - 9e-39 133.0 0.0 2e-38 131.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ETS79307.1 - 1.6e-09 37.7 0.0 3.3e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 ETS79307.1 - 1.3e-07 31.2 0.0 5.9e-07 29.0 0.0 2.0 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 ETS79307.1 - 3.7e-05 23.5 0.8 0.0016 18.2 1.0 3.0 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 ETS79307.1 - 8.2e-05 21.7 0.1 0.00013 21.1 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component MFS_1 PF07690.16 ETS79308.1 - 9.4e-30 103.7 37.3 9.4e-30 103.7 37.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_Coat_B PF05356.11 ETS79308.1 - 0.053 13.4 4.0 0.33 10.9 0.1 3.3 3 0 0 3 3 3 0 Phage Coat protein B p450 PF00067.22 ETS79309.1 - 2.4e-88 296.9 0.0 2.8e-88 296.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 ETS79310.1 - 9.4e-32 110.3 59.6 1.5e-28 99.8 39.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2417 PF10329.9 ETS79310.1 - 1.5 8.2 4.7 3.8 6.9 4.7 1.7 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Beta-lactamase PF00144.24 ETS79311.1 - 2e-34 119.3 0.5 3.2e-34 118.6 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase RasGEF PF00617.19 ETS79312.1 - 7.6e-45 153.3 0.2 1.4e-44 152.4 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ETS79312.1 - 7.9e-13 48.6 0.1 2e-12 47.3 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Nop PF01798.18 ETS79313.1 - 9.1e-80 267.4 0.2 9.1e-80 267.4 0.2 2.1 3 0 0 3 3 3 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 ETS79313.1 - 4.1e-18 65.5 0.2 1.5e-17 63.8 0.2 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain YL1 PF05764.13 ETS79313.1 - 0.073 13.2 25.7 0.11 12.6 25.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein vATP-synt_AC39 PF01992.16 ETS79314.1 - 1.4e-107 360.1 0.0 1.6e-107 360.0 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S15 PF00312.22 ETS79315.1 - 2.9e-21 75.5 0.2 9e-21 73.9 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S15 RRP7 PF12923.7 ETS79315.1 - 0.005 17.0 2.2 0.0057 16.8 0.5 1.9 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Ribosomal_S2 PF00318.20 ETS79316.1 - 1.9e-24 86.1 0.1 1.5e-13 50.5 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 ETS79316.1 - 0.0004 21.7 11.2 0.0013 20.0 11.2 1.9 1 1 0 1 1 1 1 40S ribosomal protein SA C-terminus MVL PF12151.8 ETS79316.1 - 0.19 11.6 6.5 0.052 13.4 2.7 2.1 2 0 0 2 2 2 0 Mannan-binding protein AA_permease_2 PF13520.6 ETS79317.1 - 1.3e-30 106.6 18.9 1.7e-30 106.2 18.9 1.0 1 0 0 1 1 1 1 Amino acid permease SecE PF00584.20 ETS79317.1 - 2.3 8.2 8.5 0.9 9.5 0.3 2.8 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex DUF4763 PF15960.5 ETS79318.1 - 0.0061 15.9 0.2 0.015 14.6 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) DUF883 PF05957.13 ETS79318.1 - 0.31 11.7 1.9 0.46 11.1 0.9 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 ETS79318.1 - 0.54 10.1 4.8 0.87 9.4 4.8 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain ubiquitin PF00240.23 ETS79319.1 - 5.9e-06 25.9 0.0 9.5e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 ETS79319.1 - 0.051 14.3 0.0 0.083 13.6 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Pro_isomerase PF00160.21 ETS79321.1 - 1.3e-46 158.7 0.0 1.5e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.22 ETS79322.1 - 1.8e-14 54.3 0.0 1.9e-13 51.0 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain tRNA_int_end_N2 PF12928.7 ETS79323.1 - 1.5e-24 86.0 0.1 2.6e-24 85.2 0.1 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 ETS79323.1 - 0.063 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Spt20 PF12090.8 ETS79324.1 - 0.006 16.2 19.4 0.006 16.2 19.4 2.3 2 0 0 2 2 2 1 Spt20 family EZH2_N PF18601.1 ETS79324.1 - 0.51 10.7 0.1 0.51 10.7 0.1 2.4 2 0 0 2 2 2 0 EZH2 N-terminal domain TERB2 PF15101.6 ETS79324.1 - 0.92 9.5 11.3 2.2 8.3 11.3 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Presenilin PF01080.17 ETS79324.1 - 1.4 7.6 9.8 3.5 6.3 9.8 1.5 1 0 0 1 1 1 0 Presenilin Esterase_phd PF10503.9 ETS79325.1 - 1.1e-09 38.1 0.9 2.3e-08 33.8 0.1 2.5 1 1 1 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ETS79325.1 - 0.00018 21.0 0.5 0.00033 20.2 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 ETS79325.1 - 0.012 14.3 0.1 0.058 12.1 0.1 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DNA_binding_1 PF01035.20 ETS79326.1 - 4.6e-30 103.6 0.0 7.3e-30 102.9 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain NdhL PF10716.9 ETS79327.1 - 0.19 11.7 5.7 0.52 10.3 0.7 2.4 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit GMC_oxred_N PF00732.19 ETS79328.1 - 9.1e-52 176.3 0.0 1.2e-51 175.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS79328.1 - 2.8e-29 102.5 0.0 4.9e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ETS79328.1 - 7.4e-05 22.0 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ETS79328.1 - 0.00012 21.5 0.0 0.0082 15.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS79328.1 - 0.00042 20.0 0.0 0.15 11.7 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS79328.1 - 0.00089 19.4 0.7 0.0063 16.7 0.1 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS79328.1 - 0.021 13.9 0.1 0.67 9.0 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 ETS79328.1 - 0.037 13.3 0.1 2.4 7.4 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS79328.1 - 0.11 11.6 0.0 8.9 5.3 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF1772 PF08592.11 ETS79329.1 - 2e-19 70.3 2.5 2.7e-19 69.9 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) APH PF01636.23 ETS79329.1 - 0.032 14.2 1.4 0.04 13.8 1.4 1.0 1 0 0 1 1 1 0 Phosphotransferase enzyme family Acyltransferase PF01553.21 ETS79329.1 - 0.063 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Acyltransferase ERCC4 PF02732.15 ETS79330.1 - 1.1e-26 93.9 0.0 2.4e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain Phage_Gp23 PF10669.9 ETS79330.1 - 0.0022 18.3 8.7 0.0022 18.3 8.7 1.9 1 1 0 1 1 1 1 Protein gp23 (Bacteriophage A118) Kinesin PF00225.23 ETS79332.1 - 6.1e-91 304.8 2.5 1.7e-90 303.3 0.0 2.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ETS79332.1 - 1.3e-18 67.4 0.0 7.5e-15 55.2 0.0 3.4 1 1 1 2 2 2 2 Microtubule binding Filament PF00038.21 ETS79332.1 - 0.00078 19.1 12.9 0.00078 19.1 12.9 10.8 5 2 4 10 10 10 4 Intermediate filament protein Baculo_PEP_C PF04513.12 ETS79332.1 - 0.0048 16.9 7.9 0.0048 16.9 7.9 9.9 6 2 8 14 14 14 3 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 ETS79332.1 - 0.024 15.0 1.0 0.024 15.0 1.0 13.4 12 2 2 15 15 15 0 Flagella accessory protein C (FlaC) SUIM_assoc PF16619.5 ETS79333.1 - 0.00025 21.1 0.1 0.00062 19.8 0.1 1.6 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 ETS79333.1 - 0.008 15.8 0.8 0.53 9.8 2.6 2.1 2 0 0 2 2 2 1 Spt20 family GvpG PF05120.12 ETS79333.1 - 0.15 12.1 1.0 0.86 9.7 0.2 2.2 2 0 0 2 2 2 0 Gas vesicle protein G Activator_LAG-3 PF11498.8 ETS79333.1 - 0.23 10.4 9.9 0.32 9.9 9.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 NACHT PF05729.12 ETS79334.1 - 0.0079 16.1 0.0 0.04 13.8 0.0 2.2 2 1 0 2 2 2 1 NACHT domain Goodbye PF17109.5 ETS79334.1 - 0.13 12.8 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain Thi4 PF01946.17 ETS79335.1 - 1.7e-111 371.1 0.1 2e-111 370.9 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 ETS79335.1 - 5.5e-09 36.1 0.3 7.4e-08 32.4 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS79335.1 - 8.8e-06 25.9 0.5 2.5e-05 24.4 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ETS79335.1 - 2.6e-05 23.5 0.9 4e-05 22.8 0.4 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ETS79335.1 - 0.00016 21.0 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS79335.1 - 0.0002 20.6 1.7 0.0042 16.2 0.3 2.7 2 1 1 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.6 ETS79335.1 - 0.00021 21.3 0.0 0.00044 20.3 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ETS79335.1 - 0.024 13.9 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS79335.1 - 0.052 12.3 0.3 0.075 11.7 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 ETS79335.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 ETS79335.1 - 0.15 12.2 0.0 4 7.5 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 ETS79335.1 - 0.17 10.7 0.1 0.24 10.2 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.6 ETS79335.1 - 0.2 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DNA_binding_1 PF01035.20 ETS79336.1 - 2.8e-25 88.2 0.2 3.5e-25 87.9 0.2 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain His_Phos_1 PF00300.22 ETS79337.1 - 7.9e-26 90.9 1.7 1.3e-25 90.2 0.7 1.8 1 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 ETS79337.1 - 0.063 12.6 0.1 0.09 12.1 0.1 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) ADH_N PF08240.12 ETS79339.1 - 0.11 12.4 2.2 0.24 11.3 2.2 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DHHC PF01529.20 ETS79339.1 - 0.29 11.3 8.4 0.49 10.5 8.4 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase Methyltransf_31 PF13847.6 ETS79341.1 - 9.5e-06 25.5 0.3 5.5e-05 23.0 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS79341.1 - 0.00097 19.8 0.0 0.0019 18.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS79341.1 - 0.0028 18.3 0.0 0.0071 17.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS79341.1 - 0.017 15.7 0.0 0.047 14.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 ETS79341.1 - 0.07 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 ETS79341.1 - 0.097 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.18 ETS79341.1 - 0.2 10.9 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family BTB_2 PF02214.22 ETS79342.1 - 1.5e-05 25.2 0.1 0.0024 18.2 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain NDUFB11 PF17250.2 ETS79343.1 - 0.41 11.3 3.5 0.59 10.8 1.1 2.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase 11 kDa subunit SOGA PF11365.8 ETS79343.1 - 0.5 11.5 18.1 0.1 13.7 9.8 3.2 1 1 1 2 2 2 0 Protein SOGA Laminin_II PF06009.12 ETS79343.1 - 6.9 6.7 15.8 15 5.6 0.4 2.7 2 0 0 2 2 2 0 Laminin Domain II DUF4446 PF14584.6 ETS79343.1 - 8.5 6.3 11.3 0.59 10.1 3.4 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) DENN PF02141.21 ETS79344.1 - 6.2e-39 133.9 0.0 1.1e-38 133.0 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 ETS79344.1 - 7.6e-07 29.8 0.0 2.7e-06 28.0 0.0 2.1 1 0 0 1 1 1 1 uDENN domain DUF3854 PF12965.7 ETS79344.1 - 0.21 11.6 2.2 0.84 9.6 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3854) SHE3 PF17078.5 ETS79344.1 - 0.43 10.3 15.7 0.45 10.2 14.6 1.6 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Elongin_A PF06881.11 ETS79344.1 - 0.95 10.0 13.5 0.024 15.1 5.7 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A BRE1 PF08647.11 ETS79344.1 - 7.5 6.7 16.5 4.2 7.5 6.6 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase MLANA PF14991.6 ETS79347.1 - 0.0047 17.2 0.0 0.0084 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein melan-A SR-25 PF10500.9 ETS79347.1 - 0.39 10.3 6.2 0.46 10.1 6.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pirin PF02678.16 ETS79348.1 - 2.1e-29 101.7 0.0 3.7e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 ETS79348.1 - 1.2e-25 89.8 0.0 3.1e-24 85.3 0.0 2.3 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 ETS79348.1 - 2.6e-06 27.0 0.6 0.00023 20.8 0.3 2.3 2 0 0 2 2 2 2 Cupin domain Slx4 PF09494.10 ETS79349.1 - 0.011 15.6 0.4 0.037 14.0 0.1 2.0 2 0 0 2 2 2 0 Slx4 endonuclease Lipase_GDSL_2 PF13472.6 ETS79351.1 - 6.7e-17 62.4 0.0 9.7e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.6 ETS79351.1 - 2.1e-05 24.7 0.0 0.11 12.6 0.0 2.8 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS79351.1 - 0.00034 20.6 0.0 0.00077 19.5 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF3959 PF13105.6 ETS79351.1 - 0.13 11.8 0.2 0.19 11.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Glyco_hydro_28 PF00295.17 ETS79352.1 - 1.7e-125 418.4 21.4 2.8e-125 417.7 21.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Miga PF10265.9 ETS79352.1 - 0.03 13.3 5.6 0.04 12.9 5.6 1.1 1 0 0 1 1 1 0 Mitoguardin DUF3316 PF11777.8 ETS79352.1 - 1.2 9.2 4.3 0.64 10.1 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3316) Apt1 PF10351.9 ETS79352.1 - 8.4 5.1 8.2 11 4.7 8.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3425 PF11905.8 ETS79353.1 - 3.7e-18 65.7 0.2 1.7e-16 60.3 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3425) bZIP_2 PF07716.15 ETS79355.1 - 3.7e-07 30.1 8.0 7.1e-07 29.2 8.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ETS79355.1 - 8.7e-07 28.9 6.8 8.7e-07 28.9 6.8 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 ETS79355.1 - 0.0099 16.4 3.3 0.019 15.5 3.3 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor MCC-bdg_PDZ PF10506.9 ETS79355.1 - 0.038 14.0 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Takusan PF04822.13 ETS79355.1 - 0.061 13.2 1.2 0.12 12.3 1.2 1.4 1 0 0 1 1 1 0 Takusan DUF4140 PF13600.6 ETS79355.1 - 0.29 11.6 2.6 0.85 10.1 2.6 1.8 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF2312 PF10073.9 ETS79355.1 - 0.3 10.8 3.4 0.48 10.1 3.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) PKcGMP_CC PF16808.5 ETS79355.1 - 1.3 9.0 5.7 3.1 7.7 0.5 2.3 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Clat_adaptor_s PF01217.20 ETS79356.1 - 1.2e-44 151.7 0.0 2.5e-44 150.7 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain DisA_N PF02457.16 ETS79356.1 - 0.17 11.5 0.0 1 8.9 0.0 2.0 2 0 0 2 2 2 0 DisA bacterial checkpoint controller nucleotide-binding tRNA-synt_1 PF00133.22 ETS79358.1 - 5.2e-38 130.7 0.0 8.2e-27 93.7 0.0 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 ETS79358.1 - 2.7e-17 62.6 0.1 7e-10 38.2 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 ETS79358.1 - 2.1e-12 47.3 1.3 1.3e-11 44.7 1.3 2.3 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 ETS79358.1 - 3.4e-08 33.2 0.0 6.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF1590 PF07629.11 ETS79358.1 - 0.022 14.6 0.1 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) Methyltransf_23 PF13489.6 ETS79359.1 - 2e-19 70.0 0.0 2.8e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS79359.1 - 1.2e-11 45.1 0.0 2.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS79359.1 - 8.7e-10 39.1 0.0 1.6e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS79359.1 - 1.6e-09 38.4 0.0 3.1e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS79359.1 - 6.9e-09 35.7 0.0 1.4e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS79359.1 - 0.025 13.9 0.0 0.063 12.6 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 ETS79359.1 - 0.16 11.7 0.0 0.66 9.7 0.0 1.8 2 0 0 2 2 2 0 Lysine methyltransferase Lipase_3 PF01764.25 ETS79360.1 - 1.9e-09 37.5 0.0 4.5e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ETS79360.1 - 0.008 16.8 0.6 0.016 15.8 0.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ETS79360.1 - 0.016 14.9 0.3 0.12 12.1 0.0 2.4 3 0 0 3 3 3 0 PGAP1-like protein Thioesterase PF00975.20 ETS79360.1 - 0.16 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain FAD_binding_3 PF01494.19 ETS79361.1 - 5.8e-25 88.3 0.0 1.1e-24 87.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS79361.1 - 2.4e-07 30.3 0.1 0.00038 19.8 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS79361.1 - 2.4e-05 24.8 0.4 0.0031 18.0 0.6 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS79361.1 - 3e-05 23.8 5.4 0.057 13.0 3.4 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS79361.1 - 0.00013 20.8 0.7 0.00063 18.6 0.7 1.9 1 1 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 ETS79361.1 - 0.00039 19.4 0.2 0.71 8.6 0.1 2.3 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 ETS79361.1 - 0.00048 20.3 0.3 0.0013 19.0 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS79361.1 - 0.00071 18.8 2.2 0.00088 18.5 0.3 2.1 3 0 0 3 3 3 1 FAD binding domain Amino_oxidase PF01593.24 ETS79361.1 - 0.0063 15.8 0.1 0.24 10.6 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Rossmann-like PF10727.9 ETS79361.1 - 0.039 13.8 0.7 0.095 12.6 0.1 1.9 2 0 0 2 2 2 0 Rossmann-like domain Pyr_redox_3 PF13738.6 ETS79361.1 - 0.042 13.1 0.0 0.35 10.1 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ETS79361.1 - 0.074 12.7 0.2 0.16 11.6 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 ETS79361.1 - 0.14 11.1 3.1 2.4 7.1 0.8 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein Pyridoxal_deC PF00282.19 ETS79363.1 - 7.6e-17 61.1 0.0 9.4e-17 60.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain B12D PF06522.11 ETS79363.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Pyridoxal_deC PF00282.19 ETS79364.1 - 1.6e-27 96.2 0.1 1.9e-27 96.0 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 ETS79364.1 - 0.0018 17.3 0.0 0.0018 17.3 0.0 1.2 1 1 0 1 1 1 1 Aminotransferase class-V CAP59_mtransfer PF11735.8 ETS79364.1 - 0.035 13.8 0.2 0.065 12.9 0.1 1.4 1 1 0 1 1 1 0 Cryptococcal mannosyltransferase 1 MFS_1 PF07690.16 ETS79365.1 - 2.7e-19 69.3 57.8 3.6e-17 62.3 36.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 ETS79366.1 - 3.1e-11 43.8 9.3 2.3e-09 37.8 0.1 3.1 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Alpha_kinase PF02816.18 ETS79366.1 - 3.1e-09 37.2 0.1 7.4e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 Alpha-kinase family Fez1 PF06818.15 ETS79366.1 - 0.0013 19.3 3.3 0.0027 18.2 3.3 1.5 1 0 0 1 1 1 1 Fez1 DUF724 PF05266.14 ETS79366.1 - 0.12 12.1 4.5 0.25 11.2 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Phage_HK97_TLTM PF06120.11 ETS79366.1 - 1.3 8.1 5.0 2.2 7.4 5.0 1.2 1 0 0 1 1 1 0 Tail length tape measure protein EthD PF07110.11 ETS79367.1 - 0.0023 19.0 0.5 0.0072 17.5 0.1 2.0 2 0 0 2 2 2 1 EthD domain adh_short PF00106.25 ETS79368.1 - 1.1e-35 122.9 0.1 1.4e-35 122.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS79368.1 - 6.7e-24 84.7 0.1 9.5e-24 84.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS79368.1 - 1.5e-09 38.0 0.0 2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS79368.1 - 4.5e-05 22.7 0.1 6.7e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 ETS79368.1 - 0.042 13.3 0.1 0.11 11.9 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ETS79369.1 - 9.6e-38 130.0 0.0 1.2e-37 129.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS79369.1 - 6.5e-13 49.0 0.0 1.1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ETS79369.1 - 3.4e-08 32.8 0.0 4.3e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ETS79369.1 - 1.3e-05 24.8 0.0 2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ETS79369.1 - 0.0021 17.2 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Fungal_trans PF04082.18 ETS79370.1 - 4.8e-17 61.9 0.0 1e-16 60.8 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pro_Al_protease PF02983.14 ETS79371.1 - 4.8e-11 42.6 1.0 4.8e-11 42.6 1.0 2.0 2 0 0 2 2 2 1 Alpha-lytic protease prodomain ADP_ribosyl_GH PF03747.14 ETS79372.1 - 2.1e-50 172.1 2.1 6.5e-50 170.5 2.8 1.4 2 0 0 2 2 2 1 ADP-ribosylglycohydrolase Sugar_tr PF00083.24 ETS79373.1 - 4.9e-83 279.5 19.9 5.8e-83 279.2 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS79373.1 - 2e-27 96.1 24.9 2e-27 96.1 24.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro_racemase PF05544.11 ETS79374.1 - 1.1e-60 205.4 0.0 1.5e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 Proline racemase GAF_2 PF13185.6 ETS79375.1 - 3.5e-05 24.1 0.0 4.1e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 ETS79375.1 - 0.021 15.5 0.0 0.023 15.3 0.0 1.2 1 0 0 1 1 1 0 GAF domain GAF_3 PF13492.6 ETS79375.1 - 0.045 14.1 0.0 0.056 13.8 0.0 1.2 1 0 0 1 1 1 0 GAF domain MFS_1 PF07690.16 ETS79376.1 - 6.7e-40 137.1 31.0 6.7e-40 137.1 31.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Amidohydro_1 PF01979.20 ETS79377.1 - 8.9e-46 156.8 0.0 1.1e-45 156.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS79377.1 - 2.7e-17 63.4 0.0 6.8e-13 48.9 0.0 2.4 1 1 1 2 2 2 2 Amidohydrolase family Fungal_trans PF04082.18 ETS79378.1 - 1.2e-21 76.9 3.5 2.1e-21 76.2 3.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_12 PF18658.1 ETS79378.1 - 0.12 11.9 0.1 0.38 10.4 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger C2H2-type Methyltransf_25 PF13649.6 ETS79379.1 - 1.8e-07 31.8 0.0 3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS79379.1 - 5.6e-07 30.1 0.0 1.1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS79379.1 - 3.5e-06 27.7 0.1 5.7e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS79379.1 - 1.5e-05 24.9 0.0 2.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS79379.1 - 0.0002 21.2 0.0 0.00028 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS79379.1 - 0.02 14.4 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Sec23_trunk PF04811.15 ETS79379.1 - 0.031 13.9 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain Methyltransf_18 PF12847.7 ETS79379.1 - 0.047 13.6 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain KR PF08659.10 ETS79379.1 - 0.049 13.5 0.1 0.094 12.6 0.1 1.4 1 1 0 1 1 1 0 KR domain Pox_MCEL PF03291.16 ETS79379.1 - 0.14 11.3 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme AAA PF00004.29 ETS79380.1 - 1.2e-51 174.6 0.0 2.4e-38 131.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ETS79380.1 - 6.5e-10 38.7 0.0 1.3e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 ETS79380.1 - 8e-09 36.1 0.0 0.0032 17.9 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain CDC48_2 PF02933.17 ETS79380.1 - 4.9e-08 32.6 0.1 2e-07 30.7 0.0 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 ETS79380.1 - 6.5e-07 29.7 0.0 0.0026 18.1 0.0 3.2 2 2 1 3 3 2 1 AAA domain AAA_2 PF07724.14 ETS79380.1 - 1.1e-06 28.8 0.3 5.7e-05 23.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 ETS79380.1 - 1.3e-06 28.5 0.0 0.0013 18.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 ETS79380.1 - 2.5e-06 27.4 0.0 0.0098 15.6 0.0 2.8 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.13 ETS79380.1 - 3.5e-06 26.5 0.0 0.058 12.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain PhoH PF02562.16 ETS79380.1 - 4.9e-06 26.1 0.0 0.005 16.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_14 PF13173.6 ETS79380.1 - 5.1e-06 26.6 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 ETS79380.1 - 6.1e-06 26.3 0.9 0.17 11.8 0.0 3.7 2 2 1 4 4 4 1 ATPase domain predominantly from Archaea ATPase PF06745.13 ETS79380.1 - 8.4e-06 25.3 0.1 0.00086 18.7 0.1 2.3 2 0 0 2 2 2 1 KaiC RNA_helicase PF00910.22 ETS79380.1 - 1.5e-05 25.4 0.0 0.18 12.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 ETS79380.1 - 2.4e-05 23.8 0.1 0.0051 16.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 ETS79380.1 - 4.6e-05 23.2 0.0 0.18 11.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain RuvB_N PF05496.12 ETS79380.1 - 5.1e-05 23.1 0.0 0.061 13.1 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 ETS79380.1 - 5.7e-05 22.7 0.5 0.069 12.7 0.0 2.6 3 0 0 3 3 2 2 P-loop containing dynein motor region NACHT PF05729.12 ETS79380.1 - 0.00014 21.9 0.0 4 7.3 0.0 3.6 4 0 0 4 4 3 1 NACHT domain AAA_18 PF13238.6 ETS79380.1 - 0.00014 22.4 0.0 0.077 13.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.27 ETS79380.1 - 0.00048 20.7 0.3 0.23 12.0 0.1 3.0 2 1 0 2 2 2 1 ABC transporter IstB_IS21 PF01695.17 ETS79380.1 - 0.00069 19.4 0.0 0.24 11.1 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 ETS79380.1 - 0.0014 18.2 0.1 2.9 7.4 0.0 3.0 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.6 ETS79380.1 - 0.0021 18.3 0.0 0.48 10.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ETS79380.1 - 0.0033 17.1 0.1 0.6 9.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NB-ARC PF00931.22 ETS79380.1 - 0.0053 16.0 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain TniB PF05621.11 ETS79380.1 - 0.012 15.0 0.1 6 6.2 0.0 3.1 2 1 1 3 3 3 0 Bacterial TniB protein AAA_30 PF13604.6 ETS79380.1 - 0.022 14.5 0.0 0.42 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 ETS79380.1 - 0.037 14.0 0.0 0.88 9.6 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 ETS79380.1 - 0.039 14.4 0.1 12 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 ETS79380.1 - 0.043 13.6 0.0 0.46 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ETS79380.1 - 0.046 14.0 0.0 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 ETS79380.1 - 0.063 12.4 0.0 1.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 ETS79380.1 - 0.084 13.2 0.4 0.45 10.9 0.1 2.3 2 1 0 3 3 1 0 AAA domain Sigma54_activ_2 PF14532.6 ETS79380.1 - 0.091 12.9 0.0 12 6.0 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain Bac_DnaA PF00308.18 ETS79380.1 - 0.1 12.4 0.0 20 4.9 0.0 2.6 3 0 0 3 3 2 0 Bacterial dnaA protein Cytidylate_kin PF02224.18 ETS79380.1 - 0.13 12.0 0.1 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase DUF815 PF05673.13 ETS79380.1 - 0.16 11.1 0.0 4.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_3 PF07726.11 ETS79380.1 - 0.17 11.7 0.0 0.63 9.9 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 ETS79380.1 - 0.19 11.0 0.2 2.2 7.4 0.1 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IPT PF01745.16 ETS79380.1 - 0.2 11.0 0.0 3.6 6.9 0.0 2.5 2 1 0 2 2 2 0 Isopentenyl transferase DUF3984 PF13136.6 ETS79381.1 - 0.016 14.6 6.1 0.027 13.9 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF4010 PF13194.6 ETS79381.1 - 0.61 9.7 6.0 0.061 13.0 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) CPP1-like PF11833.8 ETS79381.1 - 1.3 8.6 4.8 3.7 7.2 0.1 3.0 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like KxDL PF10241.9 ETS79382.1 - 1e-30 105.8 2.0 1.5e-30 105.3 2.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein XylR_N PF06505.11 ETS79382.1 - 0.17 11.7 0.1 0.25 11.1 0.1 1.2 1 0 0 1 1 1 0 Activator of aromatic catabolism SNRNP27 PF08648.12 ETS79383.1 - 0.15 12.2 0.1 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins Cir_N PF10197.9 ETS79385.1 - 7.6e-07 29.2 2.7 7.6e-07 29.2 2.7 4.6 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR F-box-like PF12937.7 ETS79386.1 - 7.1e-05 22.6 1.7 0.00022 21.1 0.7 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ETS79386.1 - 0.0079 16.1 1.1 0.0079 16.1 1.1 2.2 3 0 0 3 3 3 1 F-box domain IU_nuc_hydro PF01156.19 ETS79387.1 - 1e-13 51.6 0.0 1.4e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ADH_zinc_N PF00107.26 ETS79388.1 - 4.7e-26 91.3 0.5 7.3e-26 90.7 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS79388.1 - 1.5e-17 64.9 0.1 2.7e-17 64.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS79388.1 - 6e-09 35.8 0.0 1.5e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DEAD PF00270.29 ETS79390.1 - 2.1e-35 122.1 0.0 5.9e-35 120.6 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS79390.1 - 8.7e-22 77.6 0.0 2e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ETS79390.1 - 1.3e-21 76.5 0.0 2.6e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ETS79390.1 - 0.0032 17.5 0.0 0.012 15.6 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ETS79390.1 - 0.0081 16.4 0.1 0.082 13.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ETS79390.1 - 1.2 8.9 5.3 26 4.5 3.3 3.1 4 0 0 4 4 4 0 AAA domain GET2 PF08690.10 ETS79390.1 - 2.7 7.6 5.5 4.4 6.9 5.5 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Band_7 PF01145.25 ETS79391.1 - 2.7e-30 105.7 2.8 4.4e-30 105.0 2.8 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 ETS79391.1 - 0.016 14.9 0.2 0.028 14.1 0.2 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family DUF4547 PF15080.6 ETS79391.1 - 0.26 10.9 1.6 3.9 7.1 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4547) Glyco_hydro_3_C PF01915.22 ETS79392.1 - 1.8e-44 152.2 0.1 3e-44 151.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS79392.1 - 1.5e-29 103.4 0.1 6e-18 65.3 0.0 2.8 2 1 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS79392.1 - 2e-27 95.1 0.4 4.1e-27 94.1 0.4 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar_tr PF00083.24 ETS79393.1 - 1.9e-98 330.3 20.7 2.1e-98 330.1 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS79393.1 - 6e-31 107.6 46.9 6.8e-25 87.7 24.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS79393.1 - 2.8e-06 26.2 15.9 0.0005 18.8 3.3 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.13 ETS79393.1 - 0.00084 17.9 9.4 0.073 11.5 0.8 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector HK PF02110.15 ETS79393.1 - 0.064 12.6 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Ank_4 PF13637.6 ETS79394.1 - 1e-09 38.7 2.8 0.02 15.4 0.0 6.1 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS79394.1 - 9.7e-09 35.7 1.0 1.1e-06 29.1 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 ETS79394.1 - 5.6e-06 26.6 0.0 0.039 14.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ETS79394.1 - 6.2e-05 23.2 1.6 0.00067 19.9 0.1 3.4 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS79394.1 - 0.0017 18.6 0.0 0.085 13.5 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Dioxygenase_C PF00775.21 ETS79395.1 - 3.7e-06 26.5 0.2 5.9e-06 25.8 0.2 1.3 1 0 0 1 1 1 1 Dioxygenase GMC_oxred_N PF00732.19 ETS79396.1 - 5.2e-63 213.2 0.0 7.6e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS79396.1 - 1.2e-37 129.6 0.0 2.5e-37 128.6 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS79396.1 - 3.9e-06 26.2 0.1 0.0016 17.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 ETS79396.1 - 9e-06 25.5 0.2 0.035 13.7 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS79396.1 - 0.0038 17.4 0.1 0.01 16.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ETS79396.1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 ETS79396.1 - 0.092 12.0 0.0 4.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS79396.1 - 0.12 11.4 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Acetyltransf_10 PF13673.7 ETS79398.1 - 1.7e-06 28.0 0.0 2.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS79398.1 - 5.3e-06 26.8 0.0 9.7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETS79398.1 - 3.7e-05 23.8 0.3 0.0022 18.1 0.0 2.7 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS79398.1 - 0.00011 22.1 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 ETS79398.1 - 0.0002 21.6 0.0 0.00048 20.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 ETS79398.1 - 0.015 15.4 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ENTH PF01417.20 ETS79399.1 - 0.041 13.9 0.0 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 ENTH domain TauD PF02668.16 ETS79400.1 - 7.1e-10 39.1 0.0 6.2e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 ETS79400.1 - 0.0043 16.2 0.0 0.007 15.5 0.0 1.2 1 0 0 1 1 1 1 CsiD Frataxin_Cyay PF01491.16 ETS79401.1 - 8.1e-38 128.8 0.1 1.1e-37 128.4 0.1 1.2 1 0 0 1 1 1 1 Frataxin-like domain Clr5 PF14420.6 ETS79402.1 - 0.027 14.7 0.6 0.063 13.5 0.6 1.6 1 0 0 1 1 1 0 Clr5 domain DUF382 PF04037.13 ETS79403.1 - 4.5e-58 194.9 0.3 4.5e-58 194.9 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 ETS79403.1 - 6e-18 64.4 4.4 1.2e-17 63.5 4.4 1.5 1 0 0 1 1 1 1 PSP TPT PF03151.16 ETS79404.1 - 6.3e-57 193.1 10.2 7.7e-57 192.8 10.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ETS79404.1 - 7e-08 32.7 25.3 5.6e-05 23.3 10.3 3.1 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ETS79404.1 - 0.0032 16.7 14.3 0.029 13.6 14.3 2.1 1 1 0 1 1 1 1 UAA transporter family DUF2975 PF11188.8 ETS79404.1 - 6.5 6.6 8.3 2 8.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) ATP-synt_ab PF00006.25 ETS79405.1 - 6.9e-62 208.9 0.0 1.2e-61 208.1 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ETS79405.1 - 6.8e-22 77.8 0.4 1.9e-21 76.4 0.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 ETS79405.1 - 0.0017 18.7 0.0 0.11 12.9 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RnfC_N PF13375.6 ETS79405.1 - 0.012 15.6 0.0 0.035 14.1 0.0 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain NB-ARC PF00931.22 ETS79405.1 - 0.015 14.5 0.4 0.082 12.1 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 ETS79405.1 - 0.016 15.1 0.9 0.032 14.2 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase T3SS_ATPase_C PF18269.1 ETS79405.1 - 0.022 14.6 0.8 0.12 12.3 0.8 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain ATPase PF06745.13 ETS79405.1 - 0.034 13.5 0.1 0.057 12.7 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 ETS79405.1 - 0.05 13.9 0.8 0.48 10.8 0.2 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 ETS79405.1 - 0.053 13.4 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 ETS79405.1 - 0.055 13.4 0.2 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 ETS79405.1 - 0.075 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 ETS79405.1 - 0.11 12.9 0.1 0.42 11.0 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain F-box-like PF12937.7 ETS79406.1 - 0.0024 17.7 1.4 0.0045 16.9 0.2 2.1 2 0 0 2 2 2 1 F-box-like KH_10 PF17905.1 ETS79406.1 - 0.036 14.5 0.2 22 5.6 0.0 2.9 3 1 1 4 4 4 0 GLD-3 KH domain 5 AAA PF00004.29 ETS79407.1 - 5.6e-41 140.1 0.0 3.7e-38 130.9 0.0 3.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ETS79407.1 - 3.7e-10 39.5 0.1 1.1e-09 37.9 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 ETS79407.1 - 2e-06 27.7 0.0 4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ETS79407.1 - 2.7e-06 27.9 0.0 0.00099 19.5 0.0 2.8 1 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 ETS79407.1 - 0.00076 19.5 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ETS79407.1 - 0.00078 19.6 0.0 0.012 15.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 ETS79407.1 - 0.001 19.3 0.4 0.066 13.5 0.1 2.9 2 1 1 3 3 2 1 AAA domain IstB_IS21 PF01695.17 ETS79407.1 - 0.004 16.9 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 ETS79407.1 - 0.007 16.9 0.0 0.035 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ETS79407.1 - 0.016 15.2 0.0 0.058 13.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ETS79407.1 - 0.016 14.4 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 ETS79407.1 - 0.02 15.3 0.0 0.08 13.3 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_2 PF07724.14 ETS79407.1 - 0.023 14.8 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 ETS79407.1 - 0.03 13.9 0.5 2.4 7.7 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 ETS79407.1 - 0.047 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ETS79407.1 - 0.052 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 ETS79407.1 - 0.099 13.2 0.0 0.37 11.3 0.0 2.0 1 0 0 1 1 1 0 ABC transporter TniB PF05621.11 ETS79407.1 - 0.15 11.4 0.0 0.68 9.3 0.0 2.1 2 1 0 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 ETS79407.1 - 0.16 11.6 0.2 1.3 8.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 ETS79407.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE VEFS-Box PF09733.9 ETS79408.1 - 0.0029 17.4 0.0 0.0029 17.4 0.0 1.7 2 0 0 2 2 2 1 VEFS-Box of polycomb protein zf-C2H2_2 PF12756.7 ETS79408.1 - 0.013 15.8 0.4 0.032 14.6 0.4 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) YL1 PF05764.13 ETS79408.1 - 0.024 14.8 2.5 0.038 14.1 2.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Methyltransf_2 PF00891.18 ETS79410.1 - 7e-21 74.5 0.0 4e-20 72.0 0.0 2.0 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_23 PF13489.6 ETS79410.1 - 0.048 13.5 0.0 0.16 11.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF1289 PF06945.13 ETS79411.1 - 0.18 11.6 0.2 0.38 10.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) DAO PF01266.24 ETS79412.1 - 1.4e-30 107.1 1.6 1.6e-30 106.9 1.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS79412.1 - 0.0042 17.1 1.9 2.2 8.2 0.5 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ETS79412.1 - 0.043 13.1 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CN_hydrolase PF00795.22 ETS79413.1 - 7e-36 123.9 1.3 4.2e-27 95.1 0.3 2.5 2 1 0 2 2 2 2 Carbon-nitrogen hydrolase TFIIA PF03153.13 ETS79414.1 - 0.16 11.9 12.1 0.2 11.6 12.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HATPase_c_3 PF13589.6 ETS79415.1 - 4.3e-18 65.5 0.0 2.3e-16 59.9 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 ETS79415.1 - 2.4e-05 24.2 0.0 0.00056 19.7 0.0 2.6 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 ETS79415.1 - 0.00047 20.6 0.1 0.0013 19.2 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YcaO_C PF18381.1 ETS79417.1 - 0.098 12.6 1.1 0.16 11.9 1.1 1.3 1 0 0 1 1 1 0 YcaO cyclodehydratase C-terminal domain Beta-lactamase PF00144.24 ETS79418.1 - 6.1e-47 160.5 0.6 7.7e-47 160.1 0.6 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 ETS79418.1 - 0.084 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase HSF_DNA-bind PF00447.17 ETS79419.1 - 4.2e-28 97.8 0.7 8.7e-28 96.8 0.7 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding DUF5082 PF16888.5 ETS79419.1 - 0.15 12.3 6.4 0.16 12.3 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) TMEM171 PF15471.6 ETS79419.1 - 0.65 8.9 6.4 1.4 7.8 6.4 1.5 1 0 0 1 1 1 0 Transmembrane protein family 171 APG6_N PF17675.1 ETS79419.1 - 1.3 9.5 13.7 3.8 8.1 0.5 3.5 4 0 0 4 4 4 0 Apg6 coiled-coil region UPF0242 PF06785.11 ETS79419.1 - 3.4 7.7 6.8 1.1 9.3 0.1 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Pro_isomerase PF00160.21 ETS79420.1 - 3.5e-42 144.4 0.0 6.1e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 ETS79420.1 - 0.0006 20.3 0.2 0.0006 20.3 0.2 3.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4604) Sperm_Ag_HE2 PF05324.13 ETS79422.1 - 0.37 11.3 2.3 0.49 10.9 0.5 2.0 1 1 2 3 3 3 0 Sperm antigen HE2 DS PF01916.17 ETS79423.1 - 2e-134 447.3 0.0 2.4e-134 447.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Carbam_trans_N PF02543.15 ETS79423.1 - 0.032 13.9 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus Myb_DNA-binding PF00249.31 ETS79424.1 - 9.1e-09 35.4 0.0 0.0034 17.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Glycos_transf_1 PF00534.20 ETS79425.1 - 1.7e-33 115.5 0.0 4.8e-32 110.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ETS79425.1 - 4.7e-16 59.3 0.0 7.4e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 ETS79425.1 - 1.9e-14 54.3 0.2 4.6e-14 53.0 0.2 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ETS79425.1 - 9.8e-09 35.8 0.0 6.2e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 ETS79425.1 - 0.0009 19.6 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 ETS79425.1 - 0.0015 18.6 0.7 1.3 9.0 0.3 2.8 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus Glyco_trans_4_5 PF16994.5 ETS79425.1 - 0.041 13.5 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl-transferase family 4 Ank_2 PF12796.7 ETS79426.1 - 4.3e-24 84.9 0.0 2.1e-06 28.2 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS79426.1 - 4.7e-17 62.1 3.4 5.3e-06 26.9 0.0 6.9 6 2 1 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS79426.1 - 1.3e-14 52.8 5.1 2.6 8.9 0.0 8.0 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 ETS79426.1 - 2.5e-12 46.8 7.4 0.076 13.4 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 ETS79426.1 - 3.9e-10 39.7 3.8 2.5 8.7 0.0 7.4 7 0 0 7 7 7 3 Ankyrin repeat IPK PF03770.16 ETS79427.1 - 1.4e-54 185.0 0.0 2.4e-54 184.2 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase LRR_4 PF12799.7 ETS79429.1 - 5.7e-27 93.3 34.4 1.2e-06 28.8 2.4 8.4 7 2 1 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ETS79429.1 - 1.5e-23 82.3 37.8 1.3e-07 31.3 2.0 6.5 5 1 1 6 6 6 4 Leucine rich repeat LRR_9 PF14580.6 ETS79429.1 - 5.5e-09 35.8 14.8 0.0011 18.5 0.3 4.4 1 1 2 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 ETS79429.1 - 0.00053 19.8 21.9 4.4 7.6 0.0 8.4 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.33 ETS79429.1 - 0.29 11.8 23.3 44 5.2 0.5 8.5 7 2 1 8 8 8 0 Leucine Rich Repeat zf-C2H2_4 PF13894.6 ETS79430.1 - 0.0012 19.5 16.7 0.67 11.0 0.5 5.2 5 0 0 5 5 5 1 C2H2-type zinc finger zf-Di19 PF05605.12 ETS79430.1 - 0.0023 18.2 10.8 0.11 12.8 0.8 3.4 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 ETS79430.1 - 0.0076 16.2 0.6 0.082 12.9 0.8 2.4 2 0 0 2 2 2 1 BED zinc finger zf-C2H2_2 PF12756.7 ETS79430.1 - 0.049 14.0 5.7 0.15 12.4 0.8 3.3 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 ETS79430.1 - 0.068 13.0 4.2 1.7 8.5 0.1 3.4 3 0 0 3 3 3 0 GAGA factor zf-C2H2_3rep PF18868.1 ETS79430.1 - 0.07 13.8 2.5 0.15 12.7 2.5 1.5 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats DUF629 PF04780.12 ETS79430.1 - 0.11 11.0 7.5 0.33 9.4 7.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-nanos PF05741.13 ETS79430.1 - 2.9 8.2 6.9 8.5 6.7 0.0 3.3 2 1 0 2 2 2 0 Nanos RNA binding domain Eapp_C PF10238.9 ETS79430.1 - 6.9 6.7 10.5 2.4 8.2 0.8 3.2 2 2 0 2 2 2 0 E2F-associated phosphoprotein zf-C2H2_jaz PF12171.8 ETS79430.1 - 9.3 6.7 11.7 15 6.0 0.0 4.7 5 1 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Ank_2 PF12796.7 ETS79432.1 - 3.1e-26 91.8 0.7 4e-13 49.8 0.5 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS79432.1 - 7.7e-26 90.1 0.0 1.3e-07 32.0 0.1 4.5 2 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS79432.1 - 3.3e-20 70.0 0.9 0.00021 21.5 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 ETS79432.1 - 7.6e-18 64.1 5.8 0.00011 22.4 0.1 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 ETS79432.1 - 3e-16 59.3 3.1 3.7e-05 23.9 0.6 4.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Helo_like_N PF17111.5 ETS79432.1 - 2.8e-09 36.7 0.0 5.4e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 ETS79432.1 - 0.0017 18.5 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases His_Phos_1 PF00300.22 ETS79433.1 - 4.2e-12 46.2 2.4 2.6e-11 43.6 2.4 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Gln_amidase PF15644.6 ETS79433.1 - 0.053 14.5 0.1 0.11 13.5 0.1 1.6 1 0 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase adh_short PF00106.25 ETS79434.1 - 5e-53 179.5 0.4 7.9e-53 178.8 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS79434.1 - 2.2e-39 135.4 0.4 6.6e-39 133.8 0.2 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS79434.1 - 3.8e-10 40.0 0.2 5.6e-10 39.4 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ETS79434.1 - 4.4e-06 26.3 0.0 1.1e-05 25.0 0.0 1.5 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 ETS79434.1 - 1.1e-05 25.4 0.6 1.8e-05 24.7 0.6 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS79434.1 - 0.0001 22.0 0.2 0.00017 21.2 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ETS79434.1 - 0.00036 20.1 0.3 0.00066 19.2 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ETS79434.1 - 0.13 11.4 0.2 0.38 9.8 0.1 1.8 2 1 0 2 2 2 0 RmlD substrate binding domain ADH_zinc_N PF00107.26 ETS79434.1 - 0.23 11.5 1.9 0.46 10.5 1.9 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1772 PF08592.11 ETS79435.1 - 8.5e-28 97.4 2.0 8.5e-28 97.4 2.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) DEAD PF00270.29 ETS79436.1 - 1.6e-45 155.0 0.0 2.7e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS79436.1 - 8.9e-24 84.0 0.0 3.9e-23 81.9 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ETS79436.1 - 2.9e-21 75.4 0.7 5.7e-21 74.5 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ETS79436.1 - 0.0012 18.8 0.0 0.003 17.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Nop14 PF04147.12 ETS79436.1 - 0.032 12.5 13.6 0.042 12.1 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family AAA_30 PF13604.6 ETS79436.1 - 0.088 12.5 0.0 0.48 10.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain SDA1 PF05285.12 ETS79436.1 - 1.3 8.4 19.6 1.9 7.8 19.6 1.2 1 0 0 1 1 1 0 SDA1 Hamartin PF04388.12 ETS79436.1 - 1.4 7.5 7.5 2 7.0 7.5 1.1 1 0 0 1 1 1 0 Hamartin protein Pox_Ag35 PF03286.14 ETS79436.1 - 1.4 8.7 19.7 2.4 7.9 19.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FYDLN_acid PF09538.10 ETS79436.1 - 1.8 9.3 22.4 3.6 8.3 22.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Spore_coat_CotO PF14153.6 ETS79436.1 - 2.9 7.8 13.5 5 7.0 13.5 1.3 1 0 0 1 1 1 0 Spore coat protein CotO 6PF2K PF01591.18 ETS79437.1 - 1.5e-78 263.2 0.0 2e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ETS79437.1 - 5.8e-38 130.5 0.0 9.2e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 ETS79437.1 - 5.2e-07 29.9 0.0 1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 ETS79437.1 - 0.0024 17.4 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DUF816 PF05674.12 ETS79437.1 - 0.032 14.2 0.5 0.058 13.3 0.5 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) Na_Ca_ex PF01699.24 ETS79438.1 - 1e-27 97.0 30.3 5.1e-14 52.5 9.7 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YfhO PF09586.10 ETS79438.1 - 0.0054 15.0 2.4 0.0094 14.2 2.4 1.4 1 0 0 1 1 1 1 Bacterial membrane protein YfhO Wzy_C_2 PF11846.8 ETS79438.1 - 0.11 12.4 1.5 0.6 10.0 1.5 2.2 1 1 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal DUF2663 PF10864.8 ETS79438.1 - 0.17 12.3 1.8 0.19 12.1 0.1 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) DUF3328 PF11807.8 ETS79438.1 - 0.55 10.0 2.2 1.4 8.6 0.3 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3328) Stevor PF17410.2 ETS79438.1 - 1.7 8.1 3.5 2.7 7.5 3.5 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4307 PF14155.6 ETS79438.1 - 3.4 7.5 5.1 0.59 10.0 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4307) DUF829 PF05705.14 ETS79439.1 - 1.3e-40 139.8 0.2 1.9e-40 139.3 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) 2OG-FeII_Oxy_3 PF13640.6 ETS79442.1 - 1.1e-09 39.0 0.1 5.2e-08 33.7 0.1 2.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2985 PF11204.8 ETS79443.1 - 1.4e-22 79.6 5.3 2.6e-22 78.8 5.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) MRPL52 PF18699.1 ETS79443.1 - 0.79 10.0 6.7 5.2 7.3 0.1 2.5 2 0 0 2 2 2 0 Mitoribosomal protein mL52 Phage_holin_3_6 PF07332.11 ETS79443.1 - 0.81 9.7 2.3 6.9 6.7 0.3 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Pkinase PF00069.25 ETS79444.1 - 3.1e-50 171.0 1.6 4.3e-34 118.1 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS79444.1 - 2.5e-20 72.9 2.2 1.5e-18 67.0 1.0 3.7 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS79444.1 - 9e-05 21.9 0.0 0.00042 19.7 0.0 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ETS79444.1 - 0.00061 19.8 0.1 0.002 18.1 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ETS79444.1 - 0.0021 16.9 0.7 0.014 14.2 0.0 2.4 3 0 0 3 3 3 1 Fungal protein kinase Clathrin PF00637.20 ETS79446.1 - 1e-22 80.5 8.0 6e-22 78.1 2.7 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.8 ETS79446.1 - 1.7e-12 47.4 0.2 4.9e-12 45.9 0.2 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 ETS79446.1 - 6.9e-08 32.4 5.5 1.5e-07 31.3 5.5 1.6 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 ETS79446.1 - 2e-06 27.6 4.5 4e-06 26.6 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.6 ETS79446.1 - 0.00023 20.8 0.2 0.00085 19.0 0.2 2.0 1 0 0 1 1 1 1 TPR repeat zf-RING_5 PF14634.6 ETS79446.1 - 0.00027 20.8 3.4 0.0005 20.0 3.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ETS79446.1 - 0.0003 21.0 3.1 0.00064 20.0 3.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ETS79446.1 - 0.00067 19.5 2.6 0.0013 18.6 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ETS79446.1 - 0.00088 19.6 4.2 0.0017 18.6 4.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 ETS79446.1 - 0.0036 17.3 1.7 0.0093 16.0 1.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_14 PF13428.6 ETS79446.1 - 0.007 17.1 2.0 7.2 7.7 0.0 3.7 4 1 1 5 5 2 1 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 ETS79446.1 - 0.021 14.9 4.7 0.043 13.9 4.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger TPR_2 PF07719.17 ETS79446.1 - 0.089 12.9 1.6 0.25 11.6 0.2 2.7 2 0 0 2 2 1 0 Tetratricopeptide repeat Zn_Tnp_IS91 PF14319.6 ETS79446.1 - 0.12 12.4 1.6 0.18 11.8 0.3 2.0 1 1 1 2 2 2 0 Transposase zinc-binding domain HEPN PF05168.14 ETS79446.1 - 0.14 12.3 0.9 0.51 10.5 0.9 1.9 1 0 0 1 1 1 0 HEPN domain eIF3_N PF09440.10 ETS79446.1 - 0.23 11.9 3.5 0.38 11.2 1.1 2.4 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain zf-Nse PF11789.8 ETS79446.1 - 0.24 11.3 1.2 0.58 10.0 1.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 ETS79446.1 - 0.3 11.4 2.6 0.63 10.4 2.6 1.5 1 0 0 1 1 1 0 RING-like domain Zn-ribbon_8 PF09723.10 ETS79446.1 - 0.44 10.7 4.6 7.6 6.7 1.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain TPR_16 PF13432.6 ETS79446.1 - 1 10.0 5.8 2 9.1 0.1 3.8 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ETS79446.1 - 1.1 9.6 3.5 2.7 8.3 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.6 ETS79446.1 - 1.5 9.0 4.1 3.3 7.9 4.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 ETS79446.1 - 2.3 8.2 3.8 7.3 6.6 3.8 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 ANAPC3 PF12895.7 ETS79446.1 - 2.8 8.2 8.1 16 5.8 0.2 3.3 3 2 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TauD PF02668.16 ETS79447.1 - 2.2e-26 93.3 0.0 3.2e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PRA-PH PF01503.17 ETS79447.1 - 0.13 12.7 0.1 0.85 10.1 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Fungal_trans PF04082.18 ETS79448.1 - 8.6e-08 31.5 1.4 8.6e-08 31.5 1.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.21 ETS79449.1 - 4.8e-46 157.6 0.0 7.5e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 ETS79449.1 - 2.5e-44 151.7 0.1 3.8e-44 151.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ETS79449.1 - 1.7e-18 66.5 0.1 7.9e-18 64.3 0.2 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 ETS79449.1 - 3.9e-07 30.0 0.4 7.4e-07 29.1 0.4 1.4 1 0 0 1 1 1 1 PA14 domain DUF2880 PF11082.8 ETS79451.1 - 0.096 13.0 0.7 0.18 12.1 0.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2880) SNARE PF05739.19 ETS79452.1 - 4.5e-09 36.2 5.2 8.4e-09 35.3 5.2 1.5 1 0 0 1 1 1 1 SNARE domain PilJ PF13675.6 ETS79452.1 - 0.014 15.5 0.7 0.014 15.5 0.7 2.5 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Snapin_Pallidin PF14712.6 ETS79452.1 - 0.036 14.5 5.1 2.1 8.9 1.5 2.7 2 1 0 2 2 2 0 Snapin/Pallidin ABC_tran_CTD PF16326.5 ETS79452.1 - 0.048 13.9 0.9 0.048 13.9 0.9 2.2 2 1 0 2 2 2 0 ABC transporter C-terminal domain DDE_Tnp_1_2 PF13586.6 ETS79452.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain UPF0242 PF06785.11 ETS79452.1 - 8.4 6.5 8.4 65 3.6 8.4 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Meth_synt_2 PF01717.18 ETS79453.1 - 1.6e-13 50.6 0.0 2.3e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 ETS79453.1 - 0.00016 21.3 0.0 0.04 13.4 0.0 2.4 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain KH_1 PF00013.29 ETS79454.1 - 4.5e-50 167.4 13.8 6.2e-17 61.2 1.3 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ETS79454.1 - 1.7e-11 43.8 1.8 0.0095 15.7 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ETS79454.1 - 4.7e-09 36.0 5.8 0.062 13.2 0.0 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 ETS79454.1 - 0.0021 18.0 0.0 3.7 7.6 0.0 3.1 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_5 PF13184.6 ETS79454.1 - 0.039 14.1 4.2 15 5.7 0.1 3.3 3 0 0 3 3 3 0 NusA-like KH domain Baculo_PEP_C PF04513.12 ETS79455.1 - 0.0036 17.3 12.4 1 9.4 0.1 4.5 3 2 1 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus Mistic PF11458.8 ETS79455.1 - 0.025 14.5 0.1 0.21 11.6 0.0 2.7 1 1 1 2 2 2 0 Membrane-integrating protein Mistic DUF948 PF06103.11 ETS79455.1 - 6 7.2 13.7 20 5.5 0.3 5.5 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Pex14_N PF04695.13 ETS79456.1 - 9.3e-32 110.8 1.5 1.9e-31 109.8 1.5 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region AIP3 PF03915.13 ETS79456.1 - 0.013 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 CytB6-F_Fe-S PF08802.10 ETS79456.1 - 0.061 13.4 1.4 0.14 12.2 1.4 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit PAPA-1 PF04795.12 ETS79457.1 - 4.1e-28 98.0 8.2 4.1e-28 98.0 8.2 3.4 4 1 0 4 4 4 1 PAPA-1-like conserved region Rgp1 PF08737.10 ETS79458.1 - 1.6e-159 531.6 0.0 2.6e-159 530.9 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 ETS79458.1 - 0.0017 18.5 0.1 0.0095 16.0 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ETS79458.1 - 0.0072 16.8 0.0 0.24 11.8 0.0 3.0 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain WD40 PF00400.32 ETS79459.1 - 4e-14 52.8 9.9 0.002 18.9 0.0 8.7 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS79459.1 - 1.4e-06 28.5 0.0 0.089 13.1 0.0 4.9 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 ETS79459.1 - 0.02 13.9 0.0 1.2 8.1 0.0 3.3 4 0 0 4 4 4 0 VID27 C-terminal WD40-like domain Neugrin PF06413.11 ETS79460.1 - 1.3e-10 41.7 2.1 1.4e-10 41.6 0.4 1.9 1 1 1 2 2 2 1 Neugrin MRP-L20 PF12824.7 ETS79460.1 - 2.5e-06 27.8 6.2 4.1e-06 27.0 5.1 1.9 1 1 1 2 2 2 1 Mitochondrial ribosomal protein subunit L20 Frankia_peptide PF14407.6 ETS79460.1 - 0.097 12.7 0.4 2.6 8.1 0.1 2.6 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. DUF2236 PF09995.9 ETS79461.1 - 4.1e-30 105.7 0.0 6.6e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) BPL_LplA_LipB PF03099.19 ETS79464.1 - 2.9e-06 27.2 0.0 6e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.21 ETS79465.1 - 2.3e-138 460.4 0.0 2.6e-138 460.2 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Prenyltransf PF01255.19 ETS79467.1 - 1.3e-81 273.4 0.0 2e-81 272.8 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase ING PF12998.7 ETS79468.1 - 9.6e-09 35.8 0.0 0.00019 21.9 0.0 2.5 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 ETS79468.1 - 5e-06 26.3 7.8 9e-06 25.5 7.8 1.4 1 0 0 1 1 1 1 PHD-finger LRR_6 PF13516.6 ETS79469.1 - 0.00029 20.7 0.5 0.073 13.2 0.1 4.5 5 0 0 5 5 5 1 Leucine Rich repeat PPP4R2 PF09184.11 ETS79469.1 - 0.084 12.4 2.0 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 PPP4R2 LRR_4 PF12799.7 ETS79469.1 - 0.23 11.9 1.5 1.3 9.5 0.0 3.1 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) V_ATPase_I PF01496.19 ETS79470.1 - 0 1067.5 0.0 0 1067.3 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Atg14 PF10186.9 ETS79470.1 - 0.0081 15.3 1.0 0.41 9.7 0.3 2.1 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 BaxI_1 PF12811.7 ETS79470.1 - 0.025 14.2 3.9 0.026 14.1 0.0 2.2 2 0 0 2 2 2 0 Bax inhibitor 1 like CheZ PF04344.13 ETS79470.1 - 0.032 14.2 0.3 0.032 14.2 0.3 2.0 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ EzrA PF06160.12 ETS79470.1 - 0.083 11.1 7.7 0.33 9.1 1.0 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Rab5-bind PF09311.11 ETS79470.1 - 0.087 12.2 5.6 0.15 11.5 0.7 2.1 2 0 0 2 2 2 0 Rabaptin-like protein Baculo_PEP_C PF04513.12 ETS79470.1 - 0.13 12.4 4.1 1.7 8.7 0.9 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CEP209_CC5 PF16574.5 ETS79470.1 - 0.14 12.3 6.4 2.9 8.1 0.7 2.4 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 Filament PF00038.21 ETS79470.1 - 0.27 10.8 9.7 2.1 7.9 0.6 2.4 2 1 0 2 2 2 0 Intermediate filament protein Exonuc_VII_L PF02601.15 ETS79470.1 - 0.31 10.6 2.1 2.4 7.7 0.2 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit SesA PF17107.5 ETS79470.1 - 0.53 10.5 3.1 7.9 6.7 0.1 3.1 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CCDC154 PF15450.6 ETS79470.1 - 0.79 8.2 6.3 0.59 8.6 0.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 154 Golgin_A5 PF09787.9 ETS79470.1 - 0.82 9.1 8.2 2.5 7.5 1.0 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 HMMR_N PF15905.5 ETS79470.1 - 2.2 7.7 6.9 1.4 8.3 0.7 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Laminin_II PF06009.12 ETS79470.1 - 3.8 7.5 6.1 12 5.9 0.8 2.3 2 0 0 2 2 2 0 Laminin Domain II CLZ PF16526.5 ETS79470.1 - 4.4 7.7 9.5 3.7 8.0 0.6 2.8 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FAM184 PF15665.5 ETS79470.1 - 5.9 6.6 7.1 0.47 10.2 1.1 1.9 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DivIVA PF05103.13 ETS79470.1 - 6.7 6.8 6.3 26 4.9 0.2 2.5 2 0 0 2 2 2 0 DivIVA protein Sugar_tr PF00083.24 ETS79472.1 - 1e-109 367.4 18.5 1.2e-109 367.2 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS79472.1 - 1.1e-24 87.0 26.1 1.1e-24 87.0 26.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3188 PF11384.8 ETS79472.1 - 0.014 15.1 0.3 0.055 13.2 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) TPR_19 PF14559.6 ETS79472.1 - 0.048 14.2 0.2 1.3 9.5 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Lig_chan PF00060.26 ETS79472.1 - 0.79 9.6 4.8 1.8 8.4 0.2 2.9 3 0 0 3 3 3 0 Ligand-gated ion channel MFS_1 PF07690.16 ETS79473.1 - 1.2e-40 139.5 39.0 1.2e-40 139.5 39.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS79473.1 - 9.4e-14 51.1 11.0 9.4e-14 51.1 11.0 2.0 3 0 0 3 3 3 1 Sugar (and other) transporter GPR_Gpa2_C PF11970.8 ETS79473.1 - 0.26 11.4 2.1 2.2 8.4 0.4 2.9 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF1751 PF08551.10 ETS79474.1 - 4.9e-05 23.8 1.0 8.7e-05 23.0 1.0 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Uds1 PF15456.6 ETS79475.1 - 5.9e-37 126.7 5.9 5.9e-37 126.7 5.9 6.6 4 2 2 6 6 6 1 Up-regulated During Septation Laminin_II PF06009.12 ETS79475.1 - 0.0037 17.3 5.1 0.0037 17.3 5.1 6.6 5 1 1 6 6 6 2 Laminin Domain II APG6_N PF17675.1 ETS79475.1 - 0.0093 16.5 9.4 0.0093 16.5 9.4 7.5 4 2 3 7 7 7 2 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 ETS79475.1 - 0.011 16.0 4.9 0.011 16.0 4.9 7.2 5 2 1 6 6 6 0 TATA element modulatory factor 1 TATA binding HR1 PF02185.16 ETS79475.1 - 0.051 13.7 0.3 0.051 13.7 0.3 9.3 7 4 2 9 9 9 0 Hr1 repeat Glyco_transf_90 PF05686.12 ETS79476.1 - 1.2e-17 63.9 1.1 2e-13 50.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 90 Zn_clus PF00172.18 ETS79477.1 - 2.9e-07 30.5 11.5 4.4e-07 29.9 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ORC5_C PF14630.6 ETS79478.1 - 2.2e-77 260.4 0.0 3.1e-77 259.9 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 ETS79478.1 - 1.6e-11 44.9 0.0 3.5e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Alpha-amylase_C PF02806.18 ETS79479.1 - 2e-30 105.1 0.1 5.4e-30 103.7 0.1 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 ETS79479.1 - 1.4e-16 61.0 0.4 4e-13 49.7 0.1 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 ETS79479.1 - 4.9e-15 55.6 0.0 1.8e-14 53.9 0.0 2.1 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) hDGE_amylase PF14701.6 ETS79479.1 - 0.07 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain AAA_2 PF07724.14 ETS79480.1 - 1.7e-32 112.9 0.0 6.1e-32 111.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 ETS79480.1 - 2.8e-12 47.2 0.2 6.5e-12 46.0 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ETS79480.1 - 2.8e-08 33.7 0.0 5.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ETS79480.1 - 1.7e-07 31.3 0.0 4.2e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ETS79480.1 - 0.00087 19.7 0.1 0.0035 17.8 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS79480.1 - 0.0013 19.1 0.6 0.015 15.6 0.3 2.7 2 1 0 2 2 2 1 AAA domain MCM PF00493.23 ETS79480.1 - 0.0051 15.9 0.1 0.012 14.8 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain AAA_7 PF12775.7 ETS79480.1 - 0.0075 15.8 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 ETS79480.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 ETS79480.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 ETS79480.1 - 0.041 13.3 0.1 0.71 9.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein Mg_chelatase PF01078.21 ETS79480.1 - 0.11 11.9 0.0 0.55 9.6 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 ETS79480.1 - 0.17 11.6 0.0 0.79 9.4 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain COX4 PF02936.14 ETS79481.1 - 3.3e-47 160.0 0.3 3.8e-47 159.8 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV B12D PF06522.11 ETS79481.1 - 0.0059 16.4 1.0 0.18 11.6 0.0 2.4 2 0 0 2 2 2 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF1104 PF06518.11 ETS79481.1 - 0.11 12.9 0.1 0.41 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) DUF3106 PF11304.8 ETS79481.1 - 0.24 11.9 4.9 0.087 13.3 2.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) NUDIX_4 PF14815.6 ETS79482.1 - 1.5e-20 73.2 0.0 2.9e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 ETS79482.1 - 8e-18 64.9 0.0 1.5e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ETS79482.1 - 2.8e-05 23.8 0.1 0.00011 21.9 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif YcaO PF02624.16 ETS79482.1 - 0.082 12.2 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding DnaA_N PF11638.8 ETS79482.1 - 0.17 11.7 0.2 0.33 10.7 0.2 1.4 1 0 0 1 1 1 0 DnaA N-terminal domain bZIP_2 PF07716.15 ETS79483.1 - 6e-06 26.2 10.9 1.2e-05 25.2 10.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ETS79483.1 - 0.0017 18.4 10.3 0.0029 17.6 10.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor Protoglobin PF11563.8 ETS79484.1 - 2.5e-58 196.5 0.1 3e-58 196.2 0.1 1.1 1 0 0 1 1 1 1 Protoglobin DUF4512 PF14975.6 ETS79484.1 - 0.63 10.8 2.2 0.53 11.1 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) HECT PF00632.25 ETS79485.1 - 6.1e-77 259.1 0.0 8.9e-77 258.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) GFA PF04828.14 ETS79486.1 - 2.7e-09 37.2 0.1 4e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CHZ PF09649.10 ETS79487.1 - 3.4 7.2 7.3 0.63 9.6 0.4 2.8 3 0 0 3 3 3 0 Histone chaperone domain CHZ MafB19-deam PF14437.6 ETS79488.1 - 6e-09 35.8 0.0 6.5e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 ETS79488.1 - 1.2e-08 34.7 0.1 1.6e-08 34.3 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 ETS79488.1 - 0.011 15.9 0.1 0.017 15.2 0.1 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 NAD2 PF18782.1 ETS79488.1 - 0.028 14.5 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC2 PF18772.1 ETS79488.1 - 0.087 12.9 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 NAD1 PF18778.1 ETS79488.1 - 0.15 12.1 0.1 0.23 11.5 0.1 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 DUF4267 PF14087.6 ETS79489.1 - 1.5e-25 89.5 3.8 1.9e-25 89.1 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) gag-asp_proteas PF13975.6 ETS79492.1 - 0.00068 20.1 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 ETS79492.1 - 0.00072 20.2 0.0 0.0013 19.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 ETS79492.1 - 0.06 13.1 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1282 PF06930.12 ETS79494.1 - 0.049 13.4 0.1 0.074 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) TnpW PF14202.6 ETS79494.1 - 0.14 12.0 0.2 29 4.6 0.0 3.3 3 0 0 3 3 3 0 Transposon-encoded protein TnpW DiS_P_DiS PF06750.13 ETS79494.1 - 0.22 11.7 2.3 1.7 8.8 0.2 2.5 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain DUF384 PF04064.13 ETS79494.1 - 0.78 9.6 2.3 18 5.3 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF384) MFS_1 PF07690.16 ETS79495.1 - 5.6e-42 143.9 51.5 1.5e-41 142.5 48.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS79495.1 - 6.6e-19 67.8 12.8 6.6e-19 67.8 12.8 1.7 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS79495.1 - 3.5e-12 45.9 9.9 3.5e-12 45.9 9.9 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter Glyco_hydro_17 PF00332.18 ETS79497.1 - 7.5e-09 35.6 0.7 1.2e-08 35.0 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Clr5 PF14420.6 ETS79498.1 - 1.5e-20 73.1 1.6 3.2e-20 72.1 1.6 1.6 1 0 0 1 1 1 1 Clr5 domain Acyl_transf_2 PF02273.15 ETS79498.1 - 0.084 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Acyl transferase SnoaL_2 PF12680.7 ETS79499.1 - 2.5e-06 28.0 0.0 6.3e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ETS79499.1 - 0.00017 21.4 0.0 0.0004 20.2 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase YL1 PF05764.13 ETS79499.1 - 0.011 15.9 11.0 0.017 15.3 11.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 ETS79499.1 - 1.8 6.6 11.1 2.5 6.2 11.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 ETS79499.1 - 2.4 6.3 9.0 3.3 5.9 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 ETS79499.1 - 2.5 6.1 13.1 3.6 5.6 13.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 ETS79499.1 - 4.2 7.2 7.6 7.6 6.4 7.6 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region UFD1 PF03152.14 ETS79500.1 - 9.9e-70 233.5 0.0 1.2e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 GYF PF02213.16 ETS79501.1 - 2.4e-11 43.1 1.5 6.1e-11 41.8 1.5 1.7 1 0 0 1 1 1 1 GYF domain Ribosomal_S30 PF04758.14 ETS79501.1 - 3.9 7.7 10.4 38 4.6 6.9 2.6 2 0 0 2 2 2 0 Ribosomal protein S30 SUIM_assoc PF16619.5 ETS79502.1 - 0.024 14.7 3.8 0.069 13.2 3.8 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 MFS_1 PF07690.16 ETS79503.1 - 0.0001 21.4 0.3 0.00011 21.3 0.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily EthD PF07110.11 ETS79506.1 - 0.13 13.4 2.6 0.16 13.2 1.0 1.9 1 1 1 2 2 2 0 EthD domain TLP-20 PF06088.11 ETS79506.1 - 0.14 12.0 0.7 0.21 11.5 0.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) F-protein PF00469.20 ETS79507.1 - 0.031 13.9 2.5 0.041 13.5 2.5 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF3824 PF12868.7 ETS79507.1 - 0.067 13.9 5.2 0.13 13.0 5.2 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) PPL5 PF18168.1 ETS79507.1 - 0.14 11.4 2.2 0.17 11.1 2.2 1.1 1 0 0 1 1 1 0 Prim-pol family 5 PBP1_TM PF14812.6 ETS79507.1 - 2.6 8.5 8.5 5.1 7.5 8.5 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.16 ETS79509.1 - 2.6e-23 82.5 58.8 4e-22 78.6 28.7 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily SPC12 PF06645.13 ETS79509.1 - 1 9.5 10.2 0.53 10.4 0.3 3.7 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) NmrA PF05368.13 ETS79510.1 - 1.4e-13 51.0 0.0 1.8e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS79510.1 - 7.4e-06 26.0 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS79510.1 - 0.016 14.7 0.0 0.042 13.3 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 ETS79510.1 - 0.066 13.7 0.2 0.49 10.9 0.1 2.5 3 1 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain EIIBC-GUT_N PF03612.14 ETS79510.1 - 0.081 12.7 0.0 5.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus adh_short PF00106.25 ETS79511.1 - 2.3e-14 53.3 0.0 1.2e-12 47.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 ETS79511.1 - 5.8e-08 32.9 0.1 8.6e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS79511.1 - 0.026 14.0 0.2 0.062 12.8 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family TerB_C PF15615.6 ETS79511.1 - 0.15 12.3 0.3 12 6.2 0.0 2.2 2 0 0 2 2 2 0 TerB-C domain C1_2 PF03107.16 ETS79512.1 - 0.0085 16.4 5.8 0.023 15.0 5.8 1.7 1 0 0 1 1 1 1 C1 domain ZZ PF00569.17 ETS79512.1 - 0.092 12.6 6.0 0.22 11.4 6.0 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type C1_1 PF00130.22 ETS79512.1 - 0.55 10.2 3.8 1.3 9.0 3.8 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HIT PF04438.16 ETS79512.1 - 1.7 8.6 4.5 9.4 6.2 4.6 2.1 1 1 1 2 2 2 0 HIT zinc finger Histone_HNS PF00816.21 ETS79514.1 - 0.26 12.1 2.5 0.55 11.1 0.7 2.1 2 0 0 2 2 2 0 H-NS histone family Pox_Ag35 PF03286.14 ETS79514.1 - 0.62 9.8 5.0 0.11 12.3 1.5 1.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein UBA2_C PF16195.5 ETS79514.1 - 0.76 10.5 7.3 3.2 8.5 0.8 2.3 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus LPP PF04728.13 ETS79516.1 - 4.3e-05 23.8 3.1 0.22 12.0 0.0 3.6 3 1 1 4 4 4 2 Lipoprotein leucine-zipper DLP_helical PF18709.1 ETS79516.1 - 0.00053 19.3 2.0 0.00089 18.6 2.0 1.3 1 0 0 1 1 1 1 Dynamin-like helical domain Prominin PF05478.11 ETS79516.1 - 0.012 13.6 6.7 0.019 12.9 6.7 1.3 1 0 0 1 1 1 0 Prominin DUF5082 PF16888.5 ETS79516.1 - 0.023 15.0 1.8 0.055 13.7 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Spc7 PF08317.11 ETS79516.1 - 0.084 11.7 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 ETS79516.1 - 0.48 10.8 2.5 2 8.8 0.2 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 ETS79516.1 - 1.1 9.8 11.2 2.2 8.8 1.1 3.9 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 ETS79516.1 - 1.2 9.1 22.4 2.3 8.2 18.5 2.8 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 ETS79516.1 - 3.2 7.8 8.6 0.32 11.0 0.5 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Cpn60_TCP1 PF00118.24 ETS79518.1 - 4.4e-88 296.0 9.9 8.8e-88 295.1 9.9 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.20 ETS79518.1 - 0.12 12.7 0.1 0.34 11.3 0.1 1.8 1 0 0 1 1 1 0 Transcriptional regulator Cofilin_ADF PF00241.20 ETS79519.1 - 8.8e-40 135.3 0.1 1e-39 135.1 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Blt1 PF12754.7 ETS79520.1 - 4e-45 153.8 0.5 5.7e-45 153.3 0.5 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 ETS79520.1 - 1.4e-17 63.0 0.6 1.4e-17 63.0 0.6 1.7 2 0 0 2 2 2 1 Get5 carboxyl domain ubiquitin PF00240.23 ETS79520.1 - 9.3e-07 28.5 0.2 1.6e-06 27.8 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Methyltr_RsmB-F PF01189.17 ETS79521.1 - 6.9e-76 254.4 0.0 1.1e-75 253.7 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 ETS79521.1 - 3.7e-07 30.5 0.0 1.2e-06 28.9 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_25 PF13649.6 ETS79521.1 - 0.046 14.4 0.0 0.13 13.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.17 ETS79521.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin NUDE_C PF04880.13 ETS79522.1 - 5.3 7.5 8.8 6.8 7.1 8.8 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF4419 PF14388.6 ETS79523.1 - 1.5e-89 300.4 0.0 1.9e-89 300.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF3989 PF13150.6 ETS79525.1 - 0.59 9.9 0.1 0.59 9.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) DUF3176 PF11374.8 ETS79526.1 - 8.1e-36 122.5 1.3 8.1e-36 122.5 1.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) COesterase PF00135.28 ETS79527.1 - 7.8e-103 345.1 0.0 9.1e-103 344.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS79527.1 - 0.00064 19.6 0.0 0.003 17.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Amidohydro_1 PF01979.20 ETS79528.1 - 2.7e-20 73.0 2.3 2.4e-19 69.9 2.3 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS79528.1 - 1.7e-13 50.9 0.9 1.5e-06 28.0 0.1 2.5 2 1 0 2 2 2 2 Amidohydrolase family GFA PF04828.14 ETS79529.1 - 5.8e-22 77.8 0.0 8.6e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.6 ETS79529.1 - 0.04 14.4 0.0 0.092 13.3 0.0 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain PAP2 PF01569.21 ETS79532.1 - 2.3e-26 92.2 3.7 2.3e-26 92.2 3.7 2.1 3 0 0 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 ETS79532.1 - 1.2 8.8 11.2 0.25 11.0 6.8 2.2 2 1 0 2 2 2 0 PAP2 superfamily PAP2_C PF14360.6 ETS79532.1 - 7.8 7.1 6.9 3.5 8.2 2.4 2.8 2 1 0 2 2 2 0 PAP2 superfamily C-terminal DUF2085 PF09858.9 ETS79532.1 - 7.9 7.0 12.1 0.2 12.1 1.3 3.0 3 1 0 3 3 3 0 Predicted membrane protein (DUF2085) DUF202 PF02656.15 ETS79532.1 - 8.4 6.9 12.2 4.6 7.8 2.4 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF202) XRCC4 PF06632.12 ETS79534.1 - 3.9e-07 29.3 23.2 3.9e-07 29.3 23.2 1.9 1 1 1 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF507 PF04368.13 ETS79534.1 - 0.018 15.0 1.7 0.038 13.9 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF507) Aldo_ket_red PF00248.21 ETS79535.1 - 2.4e-49 168.1 0.0 2.1e-48 165.0 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family FANCI_S1-cap PF14674.6 ETS79535.1 - 0.066 13.3 0.0 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 FANCI solenoid 1 cap DUF2774 PF11242.8 ETS79535.1 - 0.088 13.0 0.1 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) HTH_AsnC-type PF13404.6 ETS79535.1 - 0.14 12.0 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain UPF0061 PF02696.14 ETS79536.1 - 1.1e-129 433.2 0.0 1.4e-129 432.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Molybdopterin PF00384.22 ETS79537.1 - 4.1e-69 233.6 0.0 2.9e-67 227.5 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 ETS79537.1 - 3.3e-20 72.5 0.0 8.7e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 ETS79537.1 - 8.2e-17 60.5 0.2 8.2e-17 60.5 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.6 ETS79537.1 - 2.5e-15 56.3 0.4 1.8e-14 53.5 0.4 2.3 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 ETS79537.1 - 0.032 14.2 3.2 1.9 8.5 0.2 3.0 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 ETS79537.1 - 0.098 12.4 0.0 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Striatin PF08232.12 ETS79538.1 - 1.9e-42 145.5 3.0 4e-42 144.4 3.0 1.6 1 0 0 1 1 1 1 Striatin family WD40 PF00400.32 ETS79538.1 - 6.7e-26 90.0 18.4 1.6e-05 25.5 0.5 7.4 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS79538.1 - 2.6e-07 30.8 0.0 3 8.2 0.0 5.0 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS79538.1 - 0.0094 14.9 0.0 0.53 9.2 0.0 2.9 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CALCOCO1 PF07888.11 ETS79538.1 - 0.038 12.8 4.6 0.066 12.1 4.6 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ADH_N_2 PF16884.5 ETS79538.1 - 0.045 13.6 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Cytochrom_D1 PF02239.16 ETS79538.1 - 0.075 11.5 0.0 0.38 9.2 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain eIF2A PF08662.11 ETS79538.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Hce2 PF14856.6 ETS79539.1 - 4.8e-09 36.4 0.2 6.2e-09 36.1 0.2 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor DUF726 PF05277.12 ETS79540.1 - 2.8e-87 292.9 0.0 3.9e-87 292.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) COesterase PF00135.28 ETS79540.1 - 0.12 11.2 0.1 0.21 10.4 0.1 1.3 1 0 0 1 1 1 0 Carboxylesterase family Glu-tRNAGln PF02686.15 ETS79541.1 - 8.8e-11 41.9 0.3 2.7e-10 40.4 0.0 2.0 2 1 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit SNAP PF14938.6 ETS79542.1 - 1.2e-114 382.5 14.9 1.4e-114 382.3 14.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP DUF2521 PF10730.9 ETS79542.1 - 0.044 13.8 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) TPR_1 PF00515.28 ETS79542.1 - 0.24 11.3 9.1 7.3 6.6 0.2 5.2 3 1 3 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 ETS79542.1 - 1 9.8 6.1 9.8 6.7 0.1 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat NUC173 PF08161.12 ETS79544.1 - 3.7e-81 271.7 0.0 2.5e-77 259.2 0.0 3.8 3 0 0 3 3 3 2 NUC173 domain HEAT PF02985.22 ETS79544.1 - 0.036 14.3 3.3 8.7 6.9 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.6 ETS79544.1 - 1.9 8.9 6.4 2.2 8.7 0.6 3.9 4 0 0 4 4 4 0 HEAT repeats V-SNARE PF05008.15 ETS79545.1 - 4.8e-22 78.1 2.0 4.8e-22 78.1 2.0 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 ETS79545.1 - 2.6e-16 59.7 1.2 2.6e-16 59.7 1.2 2.0 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus FAM76 PF16046.5 ETS79545.1 - 0.028 13.8 0.1 0.05 12.9 0.1 1.4 1 0 0 1 1 1 0 FAM76 protein Amino_oxidase PF01593.24 ETS79546.1 - 5e-21 75.5 1.5 2e-17 63.6 0.0 2.8 2 1 1 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ETS79546.1 - 1.7e-09 37.7 0.1 3.5e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS79546.1 - 0.00025 20.4 0.1 0.015 14.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS79546.1 - 0.00087 19.3 0.0 0.3 11.1 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 ETS79546.1 - 0.0055 15.5 0.0 0.88 8.2 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 ETS79546.1 - 0.0061 16.2 0.4 0.08 12.5 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ETS79546.1 - 0.15 11.3 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CtaG_Cox11 PF04442.14 ETS79547.1 - 3.1e-60 202.6 0.0 4.3e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Glyco_hydro_115 PF15979.5 ETS79550.1 - 1.6e-126 422.4 0.0 2.3e-126 421.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 ETS79550.1 - 5.8e-41 140.2 0.0 1e-40 139.4 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Peptidase_M35 PF02102.15 ETS79551.1 - 0.00018 20.5 0.0 0.07 12.0 0.0 2.1 2 0 0 2 2 2 2 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 ETS79551.1 - 0.00061 20.4 0.4 0.0074 16.8 0.1 2.6 3 0 0 3 3 3 1 Lysine-specific metallo-endopeptidase MetOD1 PF18546.1 ETS79551.1 - 0.059 13.3 0.1 0.099 12.6 0.1 1.3 1 0 0 1 1 1 0 Metanogen output domain 1 VWA PF00092.28 ETS79553.1 - 4.7e-09 36.7 0.0 2e-08 34.7 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 ETS79553.1 - 0.011 16.4 0.0 0.17 12.5 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A domain Macoilin PF09726.9 ETS79554.1 - 0.01 14.5 3.8 0.013 14.1 3.8 1.2 1 0 0 1 1 1 0 Macoilin family OmpH PF03938.14 ETS79554.1 - 0.026 14.8 19.0 0.059 13.7 19.0 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Dynactin_p22 PF07426.11 ETS79554.1 - 0.057 13.3 10.8 0.12 12.2 10.8 1.5 1 0 0 1 1 1 0 Dynactin subunit p22 Tup_N PF08581.10 ETS79554.1 - 0.13 12.6 18.0 0.41 11.0 8.1 2.4 1 1 1 2 2 2 0 Tup N-terminal Rnk_N PF14760.6 ETS79554.1 - 0.89 10.1 3.5 1.4 9.5 0.0 2.9 3 0 0 3 3 3 0 Rnk N-terminus DUF4407 PF14362.6 ETS79554.1 - 1.8 7.9 11.8 3 7.1 11.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 ETS79554.1 - 6.9 4.5 10.1 10 3.9 10.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF572 PF04502.13 ETS79554.1 - 8.7 5.9 13.2 14 5.1 13.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) CENP-Q PF13094.6 ETS79554.1 - 9.1 6.5 21.4 71 3.6 10.8 2.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit RRM_1 PF00076.22 ETS79555.1 - 2.1e-44 149.2 1.2 4.9e-20 71.1 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 ETS79555.1 - 4.7e-20 72.5 0.0 1.5e-19 70.9 0.0 1.9 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 ETS79555.1 - 7.3e-05 22.6 0.0 0.47 10.3 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 ETS79555.1 - 0.00033 20.6 0.2 0.019 15.0 0.0 2.7 2 1 0 2 2 2 1 RNA binding motif PHM7_cyt PF14703.6 ETS79555.1 - 0.019 15.2 0.1 0.61 10.3 0.1 2.9 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 ETS79555.1 - 0.02 15.0 0.1 1.6 8.9 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif RRM_5 PF13893.6 ETS79555.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phytase-like PF13449.6 ETS79556.1 - 3.5e-36 125.6 0.0 4.8e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase HET PF06985.11 ETS79557.1 - 2.1e-32 112.5 0.5 5.8e-32 111.1 0.4 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) CRM1_C PF08767.11 ETS79558.1 - 1e-128 429.0 3.6 1.8e-128 428.2 0.1 2.8 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 ETS79558.1 - 2.3e-40 138.1 10.6 1.1e-39 135.9 7.4 3.5 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 ETS79558.1 - 2.8e-32 110.2 4.7 8.7e-32 108.6 4.7 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 ETS79558.1 - 1.5e-27 95.4 2.3 4.6e-27 93.9 1.1 2.6 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 ETS79558.1 - 2.4e-19 68.5 1.4 5.2e-19 67.5 1.4 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 ETS79558.1 - 7.3e-15 54.7 0.5 2.9e-14 52.7 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3385 PF11865.8 ETS79558.1 - 0.037 13.9 4.8 0.18 11.7 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 ETS79558.1 - 0.15 12.7 0.3 5.3 7.7 0.0 3.8 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Aminotran_5 PF00266.19 ETS79559.1 - 1.3e-27 96.8 0.0 1.6e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ETS79559.1 - 2.3e-05 23.7 0.0 5.2e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II B12-binding PF02310.19 ETS79559.1 - 0.002 18.1 0.0 0.052 13.6 0.0 2.3 2 0 0 2 2 2 1 B12 binding domain DUF521 PF04412.13 ETS79559.1 - 0.026 13.2 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Metallophos_2 PF12850.7 ETS79560.1 - 1.1e-11 45.2 0.0 1.4e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Shugoshin_N PF07558.11 ETS79561.1 - 4.6e-18 64.8 5.0 8.9e-18 63.9 5.0 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 ETS79561.1 - 7.5e-10 38.4 4.9 3.2e-09 36.4 4.9 2.2 1 0 0 1 1 1 1 Shugoshin C terminus DASH_Dad2 PF08654.10 ETS79562.1 - 3.4e-34 117.2 0.7 5.9e-34 116.4 0.7 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad2 Seryl_tRNA_N PF02403.22 ETS79562.1 - 0.00039 20.6 2.1 0.001 19.2 0.3 2.4 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain IFT20 PF14931.6 ETS79562.1 - 0.0073 16.5 0.8 0.0073 16.5 0.8 1.6 2 0 0 2 2 2 1 Intraflagellar transport complex B, subunit 20 APG6_N PF17675.1 ETS79562.1 - 0.011 16.2 2.0 0.014 16.0 0.6 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region DASH_Duo1 PF08651.10 ETS79562.1 - 0.047 13.5 0.3 0.085 12.6 0.3 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 NPV_P10 PF05531.12 ETS79562.1 - 0.048 14.1 2.2 0.16 12.5 0.8 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.8 ETS79562.1 - 0.4 10.0 5.4 0.08 12.2 2.0 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) COesterase PF00135.28 ETS79564.1 - 1.2e-74 252.1 0.0 1.9e-74 251.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS79564.1 - 9.9e-05 22.3 1.0 0.00057 19.8 1.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold TAF4 PF05236.14 ETS79565.1 - 1.7e-22 80.5 0.2 2.7e-17 63.5 0.4 2.3 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.8 ETS79566.1 - 1.5e-84 282.9 0.1 2.1e-84 282.4 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 ETS79566.1 - 3.4e-29 101.4 0.0 6.3e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 ETS79566.1 - 1e-18 68.1 1.2 2e-18 67.1 1.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 ETS79566.1 - 2.9e-17 62.8 0.1 4.7e-17 62.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 ETS79566.1 - 1.2e-13 50.7 0.0 2.7e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 ETS79566.1 - 1.2e-06 28.2 1.3 2.8e-06 27.0 0.9 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ETS79566.1 - 3e-06 27.2 0.2 6.8e-06 26.1 0.2 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 ETS79566.1 - 0.015 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative beta-lactamase-like family DUF3798 PF12683.7 ETS79567.1 - 0.052 13.0 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Orthopox_F8 PF05886.11 ETS79568.1 - 0.74 10.0 4.1 8.8 6.5 0.2 2.7 2 0 0 2 2 2 0 Orthopoxvirus F8 protein Trypan_PARP PF05887.11 ETS79568.1 - 10 6.1 8.9 1.5 8.8 4.4 1.9 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) HSF_DNA-bind PF00447.17 ETS79569.1 - 2.2e-29 101.9 1.0 4e-29 101.1 1.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Mcl1_mid PF12341.8 ETS79570.1 - 3.4e-98 328.7 0.0 1.1e-96 323.7 0.0 2.5 3 1 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 ETS79570.1 - 2.3e-19 69.4 2.7 1.7e-07 31.8 0.0 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS79570.1 - 1.9e-16 60.2 0.0 1.5e-06 28.4 0.1 6.8 4 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 ETS79570.1 - 1.9e-05 23.9 0.0 4.9e-05 22.6 0.0 1.5 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 ETS79570.1 - 0.00034 20.5 0.2 0.45 10.4 0.1 3.5 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 ETS79570.1 - 0.0024 17.7 0.0 45 4.2 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 ETS79570.1 - 0.0035 16.4 0.3 13 4.6 0.0 3.9 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DNA_pol_alpha_N PF12254.8 ETS79570.1 - 0.0058 16.7 1.4 0.014 15.5 1.4 1.5 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal IKI3 PF04762.12 ETS79570.1 - 0.015 13.3 0.1 0.027 12.5 0.1 1.3 1 0 0 1 1 1 0 IKI3 family MRJP PF03022.16 ETS79570.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Major royal jelly protein WD40 PF00400.32 ETS79571.1 - 5.8e-15 55.4 15.7 0.015 16.2 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 ETS79571.1 - 0.0023 16.7 0.1 2.1 6.9 0.0 2.9 1 1 1 3 3 3 2 Nucleoporin Nup120/160 EutN_CcmL PF03319.13 ETS79571.1 - 0.035 14.7 0.0 0.092 13.3 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutN/carboxysome SGL PF08450.12 ETS79571.1 - 0.044 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Ank_5 PF13857.6 ETS79572.1 - 2.3e-27 94.7 3.2 6.8e-07 29.5 0.1 6.6 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS79572.1 - 3.7e-26 91.5 3.4 2.9e-08 34.2 0.1 4.5 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS79572.1 - 4.7e-25 87.6 5.6 0.0077 16.8 0.0 7.9 6 2 2 8 8 7 6 Ankyrin repeats (many copies) Ank PF00023.30 ETS79572.1 - 1.6e-20 72.5 9.0 9.1e-06 25.9 0.1 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 ETS79572.1 - 2.5e-14 52.0 6.0 0.012 16.1 0.0 8.3 8 0 0 8 8 8 3 Ankyrin repeat NACHT PF05729.12 ETS79572.1 - 2.7e-08 33.9 0.1 5.2e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ETS79572.1 - 5.2e-05 23.5 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 ETS79572.1 - 5.7e-05 22.5 2.4 0.18 11.0 1.0 2.3 2 0 0 2 2 2 2 KAP family P-loop domain AAA_16 PF13191.6 ETS79572.1 - 0.0002 21.8 0.0 0.00055 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 ETS79572.1 - 0.0046 17.5 0.0 0.028 15.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 ETS79572.1 - 0.0049 17.2 0.8 0.0095 16.3 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA PF00004.29 ETS79572.1 - 0.0054 17.1 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 ETS79572.1 - 0.044 14.3 0.0 0.11 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ETS79572.1 - 0.058 13.6 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 ETS79572.1 - 0.064 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 MMR_HSR1 PF01926.23 ETS79572.1 - 0.098 12.8 0.1 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 ETS79572.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ETS79572.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_10 PF12846.7 ETS79572.1 - 0.13 11.2 0.1 2.8 6.8 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AFG1_ATPase PF03969.16 ETS79572.1 - 0.14 11.0 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase AAA_24 PF13479.6 ETS79572.1 - 0.15 11.8 0.1 0.68 9.6 0.0 2.1 1 1 1 2 2 2 0 AAA domain SAPS PF04499.15 ETS79573.1 - 4.1 6.1 11.0 7.1 5.3 11.0 1.5 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRN3 PF05327.11 ETS79573.1 - 9.3 4.7 10.6 15 4.0 10.6 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pkinase PF00069.25 ETS79574.1 - 2.5e-75 253.2 0.0 3.4e-75 252.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS79574.1 - 1.1e-30 106.8 0.0 6.7e-22 78.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ETS79574.1 - 5.9e-06 25.8 0.0 1.1 8.5 0.0 3.2 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 ETS79574.1 - 0.022 13.5 1.1 0.044 12.6 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 ETS79574.1 - 0.026 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ETS79574.1 - 0.045 13.7 0.6 0.83 9.5 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family AT_hook PF02178.19 ETS79575.1 - 0.23 11.4 19.3 0.8 9.8 4.0 2.8 2 0 0 2 2 2 0 AT hook motif DFRP_C PF16543.5 ETS79576.1 - 5.3e-27 94.1 9.3 5.3e-27 94.1 9.3 3.7 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 ETS79576.1 - 4.9e-06 26.3 8.7 1.2e-05 25.1 0.9 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 ETS79576.1 - 6.9e-06 26.7 3.6 6.9e-06 26.7 3.6 3.6 2 2 2 4 4 4 2 Torus domain zf-CCCH_4 PF18044.1 ETS79576.1 - 0.00015 21.5 7.2 0.0027 17.4 1.9 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ETS79576.1 - 0.00043 20.3 5.7 0.00043 20.3 5.7 3.1 3 0 0 3 3 3 1 Zinc finger domain RE_BstXI PF09552.10 ETS79576.1 - 0.04 13.1 0.1 0.11 11.7 0.3 1.6 2 0 0 2 2 2 0 BstXI restriction endonuclease zf-CCCH_2 PF14608.6 ETS79576.1 - 0.46 11.0 13.3 0.31 11.6 4.7 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 ETS79576.1 - 1.6 9.0 10.3 0.25 11.6 1.0 2.9 2 1 0 3 3 3 0 Zinc-finger containing family RRM_1 PF00076.22 ETS79577.1 - 2.9e-16 59.0 0.0 4.7e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 ETS79577.1 - 0.00022 21.7 2.8 0.00022 21.7 2.8 3.0 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 ETS79577.1 - 0.0021 17.9 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif Methyltransf_10 PF05971.12 ETS79578.1 - 0.11 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 RNA methyltransferase Reprolysin_5 PF13688.6 ETS79579.1 - 8.8e-57 192.4 9.2 8.8e-57 192.4 9.2 2.7 2 1 1 3 3 3 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 ETS79579.1 - 5.3e-49 166.6 4.7 9.6e-49 165.8 4.7 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 ETS79579.1 - 6e-49 166.6 4.4 6e-49 166.6 4.4 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 ETS79579.1 - 2.7e-16 60.1 35.4 2.7e-16 60.1 35.4 4.6 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 ETS79579.1 - 9.6e-11 42.3 0.1 3.2e-10 40.6 0.1 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 ETS79579.1 - 0.00098 19.6 11.8 0.00098 19.6 11.8 4.9 1 1 2 3 3 3 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 ETS79579.1 - 0.012 15.8 0.1 0.034 14.4 0.1 1.7 1 0 0 1 1 1 0 Reprolysin family propeptide DNA_pol_E_B PF04042.16 ETS79581.1 - 4.7e-48 163.3 0.0 6.6e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 ETS79581.1 - 1e-39 135.6 0.0 1.7e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain WD40 PF00400.32 ETS79582.1 - 4.5e-25 87.4 13.5 1e-08 35.7 0.7 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.12 ETS79582.1 - 6.5e-16 58.6 0.1 1.1e-15 57.9 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 ETS79582.1 - 0.0029 16.3 2.8 0.58 8.7 0.3 3.1 1 1 1 3 3 3 2 Nucleoporin Nup120/160 DNA_pol_A_exo1 PF01612.20 ETS79583.1 - 9.3e-14 51.5 0.0 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease RNA_pol_L_2 PF13656.6 ETS79584.1 - 2.2e-23 81.8 0.0 3e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 ETS79584.1 - 3.3e-07 29.6 0.0 5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Mannosyl_trans3 PF11051.8 ETS79584.1 - 0.062 12.6 0.0 0.074 12.4 0.0 1.1 1 0 0 1 1 1 0 Mannosyltransferase putative AA_permease PF00324.21 ETS79585.1 - 1.8e-61 208.2 29.3 2.2e-61 207.9 29.3 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 ETS79585.1 - 2.5e-21 76.2 2.0 6e-09 35.4 0.1 3.2 3 0 0 3 3 3 3 Solute carrier family 12 AA_permease_2 PF13520.6 ETS79585.1 - 1.8e-13 50.1 33.3 3.3e-13 49.3 33.3 1.3 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 ETS79586.1 - 9.2e-82 274.9 39.1 1.1e-81 274.7 39.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CorA PF01544.18 ETS79588.1 - 2.5e-11 43.4 2.7 2.5e-11 43.4 2.7 2.4 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Claudin_2 PF13903.6 ETS79588.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction GWT1 PF06423.12 ETS79588.1 - 0.17 12.0 0.1 0.4 10.8 0.1 1.6 1 0 0 1 1 1 0 GWT1 Methyltransf_2 PF00891.18 ETS79589.1 - 2.1e-25 89.2 0.0 2.7e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 ETS79589.1 - 3e-05 24.0 0.2 6.6e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.5 ETS79589.1 - 0.0036 17.3 0.1 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 Dimerisation domain Rrf2 PF02082.20 ETS79589.1 - 0.17 12.2 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Spt4 PF06093.13 ETS79591.1 - 5.7e-32 109.7 0.3 7e-32 109.4 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger PPP5 PF08321.12 ETS79593.1 - 6e-33 113.0 1.4 9.7e-33 112.3 0.4 1.9 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 ETS79593.1 - 2.1e-32 113.3 0.1 3.2e-32 112.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 ETS79593.1 - 4.7e-18 64.2 2.8 1.3e-05 24.8 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 ETS79593.1 - 4.4e-14 51.4 1.8 0.0015 18.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 ETS79593.1 - 6.4e-10 38.6 4.4 3.4e-05 23.4 0.0 3.4 3 0 0 3 3 3 2 TPR repeat TPR_17 PF13431.6 ETS79593.1 - 3.2e-08 33.4 4.8 0.0044 17.3 0.1 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 ETS79593.1 - 7.9e-06 25.9 0.0 0.036 14.2 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ETS79593.1 - 1.1e-05 25.2 2.7 1.2 9.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ETS79593.1 - 1.3e-05 25.8 0.1 0.084 13.5 0.0 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS79593.1 - 0.0012 19.3 0.1 1.2 9.7 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 ETS79593.1 - 0.0015 19.2 0.6 3.4 8.7 0.0 3.2 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ETS79593.1 - 0.0094 16.2 0.0 6.6 7.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Kelch_4 PF13418.6 ETS79593.1 - 0.14 12.2 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Galactose oxidase, central domain UPF0029 PF01205.19 ETS79594.1 - 1.2e-33 115.6 0.0 1.8e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 ETS79594.1 - 5.8e-09 36.3 0.0 1.1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.26 ETS79594.1 - 0.12 12.1 0.0 0.58 9.8 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme CoA_transf_3 PF02515.17 ETS79595.1 - 1.8e-69 234.7 0.0 2.2e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III DNMT1-RFD PF12047.8 ETS79596.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain TruB_N PF01509.18 ETS79597.1 - 6e-45 153.2 0.2 1.7e-44 151.8 0.0 1.7 1 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 ETS79597.1 - 6.9e-07 29.3 0.0 1.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain ERG2_Sigma1R PF04622.12 ETS79598.1 - 1.3e-97 325.2 0.2 1.5e-97 325.0 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein EXOSC1 PF10447.9 ETS79599.1 - 3.9e-23 82.1 2.8 5.6e-15 55.9 0.1 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 ETS79599.1 - 3e-12 46.1 0.0 6.4e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Sec2p PF06428.11 ETS79600.1 - 1.1e-11 44.5 6.7 1.1e-11 44.5 6.7 2.3 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p SlyX PF04102.12 ETS79600.1 - 0.051 14.2 15.9 0.15 12.7 0.5 3.2 3 1 0 3 3 3 0 SlyX DUF3573 PF12097.8 ETS79600.1 - 0.065 12.1 0.1 0.093 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) YwqJ-deaminase PF14431.6 ETS79600.1 - 0.23 11.7 4.0 2.6 8.3 0.5 2.5 2 0 0 2 2 2 0 YwqJ-like deaminase HAUS-augmin3 PF14932.6 ETS79600.1 - 0.81 9.2 8.7 4.7 6.7 4.3 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 MbeD_MobD PF04899.12 ETS79600.1 - 1.6 8.9 6.8 11 6.3 2.1 3.3 2 1 1 3 3 3 0 MbeD/MobD like APG6_N PF17675.1 ETS79600.1 - 2.3 8.8 12.3 26 5.3 0.1 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 ETS79600.1 - 6.1 6.3 16.7 1.4e+03 -1.5 16.7 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 ETS79600.1 - 7.2 5.9 20.1 6.2 6.1 10.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Mito_fiss_reg PF05308.11 ETS79600.1 - 9.9 6.2 14.5 1.1 9.3 8.9 2.2 1 1 2 3 3 3 0 Mitochondrial fission regulator MKT1_C PF12246.8 ETS79601.1 - 3.3e-69 232.8 0.0 5.2e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 ETS79601.1 - 2.3e-29 101.6 0.1 5.1e-29 100.5 0.1 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 ETS79601.1 - 0.00024 21.5 0.0 0.00073 20.0 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain TcdA_TcdB_pore PF12920.7 ETS79601.1 - 0.039 12.2 0.0 0.061 11.6 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain DUF4048 PF13257.6 ETS79602.1 - 7.6e-18 65.3 4.7 5.6e-17 62.4 0.4 4.9 2 1 2 5 5 5 3 Domain of unknown function (DUF4048) DNA_ligase_A_M PF01068.21 ETS79603.1 - 5.1e-23 81.8 0.1 9.3e-23 80.9 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ETS79603.1 - 1e-22 81.3 0.0 2.6e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 ETS79603.1 - 1.2e-05 25.7 0.0 2.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 RNA ligase PNKP_ligase PF16542.5 ETS79603.1 - 0.028 13.9 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain mRNA_cap_enzyme PF01331.19 ETS79603.1 - 0.06 13.2 0.1 0.18 11.6 0.1 1.8 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain Glyco_transf_41 PF13844.6 ETS79603.1 - 0.14 10.6 0.1 0.51 8.7 0.0 1.9 2 1 0 2 2 2 0 Glycosyl transferase family 41 Hamartin PF04388.12 ETS79603.1 - 3.4 6.2 13.0 2.6 6.6 11.1 1.7 2 0 0 2 2 2 0 Hamartin protein DIOX_N PF14226.6 ETS79604.1 - 9.5e-22 78.0 0.0 1.5e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS79604.1 - 1.8e-13 50.8 0.0 3.5e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ATP-synt_ab PF00006.25 ETS79605.1 - 8.8e-109 362.1 0.0 1.3e-108 361.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 ETS79605.1 - 1.2e-48 163.9 0.1 2.4e-48 163.0 0.1 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 ETS79605.1 - 1.1e-14 54.7 3.5 2.6e-14 53.5 3.5 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Ndc1_Nup PF09531.10 ETS79605.1 - 3.7 6.1 8.6 0.84 8.2 5.6 1.4 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Ferritin_2 PF13668.6 ETS79606.1 - 3e-40 137.6 0.7 5e-40 136.8 0.7 1.4 1 0 0 1 1 1 1 Ferritin-like domain LIME1 PF15332.6 ETS79606.1 - 0.69 9.5 1.9 0.67 9.5 0.7 1.5 2 0 0 2 2 2 0 Lck-interacting transmembrane adapter 1 RNB PF00773.19 ETS79607.1 - 2.4e-76 257.2 0.0 3.9e-76 256.5 0.0 1.4 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 ETS79607.1 - 4.6e-26 91.0 0.0 1.3e-25 89.5 0.0 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 ETS79607.1 - 5.4e-26 90.4 0.0 1.3e-25 89.2 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 ETS79607.1 - 2.4e-06 27.6 0.0 0.0073 16.4 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 ETS79607.1 - 0.022 14.5 0.0 0.057 13.1 0.0 1.7 1 0 0 1 1 1 0 Rrp44-like cold shock domain Epsilon_antitox PF08998.11 ETS79607.1 - 0.23 11.8 1.2 2.1 8.7 0.3 2.4 2 0 0 2 2 2 0 Bacterial epsilon antitoxin NPR3 PF03666.13 ETS79607.1 - 3.1 6.5 6.4 1.7 7.4 0.1 2.5 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 GLE1 PF07817.13 ETS79608.1 - 7.5e-58 195.7 0.0 1.2e-57 195.0 0.0 1.2 1 0 0 1 1 1 1 GLE1-like protein Cas_Csn2 PF09711.10 ETS79608.1 - 0.1 12.2 0.3 0.19 11.4 0.3 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csn2) Macoilin PF09726.9 ETS79608.1 - 0.12 11.0 12.5 1.2 7.6 13.0 1.8 1 1 0 1 1 1 0 Macoilin family YabA PF06156.13 ETS79608.1 - 2.2 9.0 8.0 1.9 9.2 0.6 2.8 3 0 0 3 3 3 0 Initiation control protein YabA Syntaxin-6_N PF09177.11 ETS79609.1 - 1.2e-26 93.1 0.7 3.9e-26 91.5 0.1 1.9 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 ETS79609.1 - 0.00082 19.3 0.5 0.0018 18.2 0.5 1.6 1 0 0 1 1 1 1 SNARE domain Prominin PF05478.11 ETS79609.1 - 0.0016 16.5 0.2 0.0019 16.3 0.1 1.3 1 1 0 1 1 1 1 Prominin Use1 PF09753.9 ETS79609.1 - 0.0055 16.5 0.8 0.0072 16.1 0.8 1.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF745 PF05335.13 ETS79609.1 - 0.032 14.0 12.2 0.33 10.7 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) KASH_CCD PF14662.6 ETS79609.1 - 0.053 13.4 0.1 0.053 13.4 0.1 2.2 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 ETS79609.1 - 0.99 8.2 7.4 0.69 8.7 0.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 ETS79609.1 - 3 7.9 6.9 14 5.7 0.0 2.4 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Methyltransf_32 PF13679.6 ETS79610.1 - 1.3e-23 83.7 0.0 2.2e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Osmo_CC PF08946.10 ETS79610.1 - 0.095 13.0 0.6 0.2 11.9 0.6 1.5 1 0 0 1 1 1 0 Osmosensory transporter coiled coil ACT_7 PF13840.6 ETS79611.1 - 7.7e-21 73.7 0.9 2e-17 62.7 0.1 2.5 2 0 0 2 2 2 2 ACT domain DUF3402 PF11882.8 ETS79613.1 - 8.8e-199 661.4 0.0 1.1e-198 661.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 ETS79613.1 - 6.6e-86 288.1 0.0 1.1e-85 287.4 0.0 1.4 1 0 0 1 1 1 1 N1221-like protein PAP2 PF01569.21 ETS79614.1 - 3.4e-13 49.5 6.5 4.6e-13 49.1 5.1 1.9 1 1 0 1 1 1 1 PAP2 superfamily UbiA PF01040.18 ETS79614.1 - 0.002 17.5 3.0 0.002 17.5 3.0 1.6 2 0 0 2 2 2 1 UbiA prenyltransferase family DUF212 PF02681.14 ETS79614.1 - 0.012 15.7 0.0 0.23 11.6 0.0 2.3 2 0 0 2 2 2 0 Divergent PAP2 family IBR PF01485.21 ETS79615.1 - 3.4e-22 78.4 36.4 1.3e-16 60.5 3.0 3.9 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RWD PF05773.22 ETS79615.1 - 4.4e-18 65.6 0.1 8.8e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 ETS79615.1 - 0.00011 22.4 5.6 0.00011 22.4 5.6 4.0 3 1 1 4 4 4 2 Ring finger domain zf-RING_UBOX PF13445.6 ETS79615.1 - 0.00083 19.3 5.6 0.00083 19.3 5.6 3.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ETS79615.1 - 0.0013 18.6 5.3 0.0013 18.6 5.3 4.3 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ETS79615.1 - 0.0047 16.7 6.6 0.0047 16.7 6.6 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 ETS79615.1 - 0.015 15.3 5.3 0.015 15.3 5.3 3.7 3 1 0 3 3 3 0 zinc-RING finger domain NDT80_PhoG PF05224.12 ETS79616.1 - 1.1e-32 113.7 0.0 8.7e-32 110.8 0.0 2.3 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family DUF2011 PF09428.10 ETS79617.1 - 8.6e-18 64.4 0.2 6.7e-17 61.5 0.0 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) Ank_5 PF13857.6 ETS79618.1 - 0.022 15.1 0.1 4.1 7.8 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 ETS79619.1 - 9.2e-06 25.1 0.0 1.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Fungal_trans PF04082.18 ETS79620.1 - 2.5e-33 115.2 0.4 2.5e-33 115.2 0.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS79620.1 - 4.9e-08 33.0 9.6 9.6e-08 32.0 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S9 PF00326.21 ETS79621.1 - 1.3e-19 70.5 0.4 2.1e-19 69.9 0.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 ETS79621.1 - 0.00011 21.8 0.1 0.00021 20.9 0.1 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 ETS79621.1 - 0.00039 20.1 0.1 0.19 11.3 0.2 2.5 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 ETS79621.1 - 0.0019 18.8 0.6 0.0019 18.8 0.6 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS79621.1 - 0.03 13.6 0.8 2 7.6 0.1 2.2 1 1 0 2 2 2 0 Serine aminopeptidase, S33 FSH1 PF03959.13 ETS79621.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.11 ETS79621.1 - 0.17 11.8 0.1 4.8 7.1 0.1 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal TRI12 PF06609.13 ETS79622.1 - 6.2e-62 209.9 23.6 8.1e-62 209.5 23.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ETS79622.1 - 2e-26 92.8 36.3 2e-26 92.8 36.3 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS79622.1 - 9.1e-12 44.6 5.2 9.1e-12 44.6 5.2 2.7 3 1 0 3 3 3 2 Sugar (and other) transporter GWT1 PF06423.12 ETS79622.1 - 0.074 13.2 0.0 0.36 11.0 0.0 2.2 1 0 0 1 1 1 0 GWT1 DUF3445 PF11927.8 ETS79624.1 - 6e-64 215.8 0.1 7.8e-64 215.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Ctr PF04145.15 ETS79625.1 - 3.1e-43 147.9 0.0 3.8e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family TMEM190 PF15431.6 ETS79625.1 - 0.12 12.5 0.2 3.2 7.9 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 190 Herpes_LMP1 PF05297.11 ETS79625.1 - 0.72 9.0 2.4 0.55 9.4 0.0 1.8 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Ferric_reduct PF01794.19 ETS79626.1 - 8.1e-25 87.3 9.8 1.7e-24 86.3 9.8 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ETS79626.1 - 1.2e-20 74.2 0.0 1.9e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ETS79626.1 - 5.5e-10 39.3 0.1 1.6e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 ETS79626.1 - 9.3e-10 39.1 0.0 4.8e-08 33.6 0.0 2.5 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain Abhydrolase_1 PF00561.20 ETS79627.1 - 0.00076 19.2 0.1 0.0029 17.3 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold ADH_N PF08240.12 ETS79628.1 - 1e-10 41.4 0.1 3.6e-09 36.5 0.0 2.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS79628.1 - 2.2e-08 34.1 0.3 4.1e-08 33.3 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Tyrosinase PF00264.20 ETS79629.1 - 1.3e-43 149.9 5.0 3.9e-43 148.3 5.0 1.8 1 1 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 ETS79629.1 - 2.1e-26 93.0 0.0 3.2e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Tyosinase C-terminal domain BNR PF02012.20 ETS79630.1 - 1.7e-07 30.2 17.3 1.3 9.3 0.2 6.4 6 0 0 6 6 6 5 BNR/Asp-box repeat PSII_BNR PF14870.6 ETS79630.1 - 1.8e-05 24.2 5.8 0.0054 16.0 0.5 3.9 3 1 1 4 4 4 2 Photosynthesis system II assembly factor YCF48 Sortilin-Vps10 PF15902.5 ETS79630.1 - 4.2e-05 22.5 3.6 0.0072 15.2 0.0 3.1 3 1 1 4 4 4 3 Sortilin, neurotensin receptor 3, COG5 PF10392.9 ETS79631.1 - 0.036 14.2 0.8 0.14 12.3 0.2 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 CorA PF01544.18 ETS79631.1 - 0.3 10.4 13.6 2.8 7.2 13.6 2.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 ETS79632.1 - 8e-42 143.4 48.6 1.2e-33 116.5 30.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AfaD PF05775.12 ETS79632.1 - 0.054 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein SnoaL_2 PF12680.7 ETS79633.1 - 0.0041 17.7 0.0 0.0071 17.0 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain CAP PF00188.26 ETS79634.1 - 7.5e-20 72.0 2.5 7.5e-20 72.0 2.5 1.9 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Cyclase PF04199.13 ETS79635.1 - 8.4e-11 42.3 0.0 1.1e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase DnaJ_C PF01556.18 ETS79636.1 - 7.9e-23 81.2 0.0 1.2e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain Helo_like_N PF17111.5 ETS79636.1 - 5.2e-06 26.0 0.1 8.6e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Baculo_PEP_C PF04513.12 ETS79636.1 - 0.0074 16.3 1.3 1.3 9.1 0.1 2.3 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus EST1 PF10374.9 ETS79636.1 - 0.012 16.2 0.1 0.029 15.0 0.1 1.6 1 0 0 1 1 1 0 Telomerase activating protein Est1 CCDC24 PF15669.5 ETS79636.1 - 0.066 13.1 8.3 1.2 9.0 0.0 3.6 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 24 family Seryl_tRNA_N PF02403.22 ETS79636.1 - 0.12 12.6 0.9 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cob_adeno_trans PF01923.18 ETS79636.1 - 0.14 12.2 0.3 0.52 10.4 0.0 1.9 2 0 0 2 2 2 0 Cobalamin adenosyltransferase Syntaxin-6_N PF09177.11 ETS79636.1 - 1.7 9.3 7.2 1.6 9.3 0.1 3.4 2 1 1 4 4 4 0 Syntaxin 6, N-terminal TPP_enzyme_N PF02776.18 ETS79637.1 - 2.3e-34 118.5 0.2 3.6e-34 117.9 0.2 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ETS79637.1 - 8.4e-19 67.7 0.0 1.4e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ETS79637.1 - 2.9e-18 66.1 0.1 9e-17 61.3 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Aminotran_1_2 PF00155.21 ETS79638.1 - 3.1e-19 69.4 0.0 3.9e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ETS79638.1 - 9e-05 21.9 0.0 0.00019 20.9 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.7 ETS79638.1 - 0.025 13.4 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase CorA PF01544.18 ETS79640.1 - 0.013 14.8 0.1 0.021 14.1 0.1 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2919 PF11143.8 ETS79640.1 - 0.042 14.2 0.6 0.074 13.4 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) p450 PF00067.22 ETS79641.1 - 1.9e-63 214.9 0.0 2.8e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 ETS79641.1 - 0.078 11.8 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain MIP PF00230.20 ETS79642.1 - 1.9e-48 165.1 15.8 2.6e-48 164.7 15.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein APH PF01636.23 ETS79644.1 - 4.8e-18 66.0 0.0 1.9e-17 64.0 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETS79644.1 - 4.7e-07 29.6 0.0 1.5e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 ETS79644.1 - 0.011 15.1 0.0 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain HET PF06985.11 ETS79645.1 - 2.8e-29 102.4 0.1 5.4e-21 75.5 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) AA_permease_2 PF13520.6 ETS79646.1 - 5.8e-52 176.9 44.2 6.5e-52 176.8 44.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS79646.1 - 1.1e-12 47.3 34.2 1.4e-12 46.9 34.2 1.1 1 0 0 1 1 1 1 Amino acid permease Ank_2 PF12796.7 ETS79647.1 - 4.4e-32 110.5 8.1 3.6e-06 27.5 0.1 9.5 4 2 4 9 9 9 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS79647.1 - 4.5e-26 88.1 17.4 0.025 15.1 0.0 14.7 16 0 0 16 16 16 5 Ankyrin repeat Ank_4 PF13637.6 ETS79647.1 - 1.9e-23 82.5 12.9 3.6e-05 24.2 0.1 11.1 10 3 3 13 13 13 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS79647.1 - 8e-11 42.0 0.0 0.053 13.9 0.1 6.8 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS79647.1 - 2.7e-09 37.0 13.3 1.3 9.6 0.2 10.8 13 0 0 13 13 13 2 Ankyrin repeat Clr5 PF14420.6 ETS79647.1 - 3.7e-06 27.1 1.9 9e-06 25.8 1.9 1.7 1 0 0 1 1 1 1 Clr5 domain NACHT PF05729.12 ETS79648.1 - 1.7e-08 34.6 0.6 5.1e-08 33.0 0.1 2.2 2 0 0 2 2 2 1 NACHT domain SesA PF17107.5 ETS79648.1 - 2.6e-06 27.6 0.6 7.5e-06 26.1 0.6 1.9 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_16 PF13191.6 ETS79648.1 - 6.8e-05 23.3 0.8 0.0003 21.2 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 ETS79648.1 - 0.00029 21.2 0.0 0.024 15.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 ETS79648.1 - 0.001 18.3 0.1 0.0037 16.5 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 ETS79648.1 - 0.0016 18.7 0.3 0.11 12.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 ETS79648.1 - 0.0041 16.4 0.1 0.21 10.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 ETS79648.1 - 0.013 16.1 0.0 0.054 14.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 ETS79648.1 - 0.016 15.2 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Helo_like_N PF17111.5 ETS79648.1 - 0.021 14.2 2.4 0.055 12.8 2.3 1.8 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins ABC_tran PF00005.27 ETS79648.1 - 0.03 14.8 0.0 0.16 12.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 ETS79648.1 - 0.031 14.4 0.0 0.085 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ETS79648.1 - 0.032 14.3 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 ETS79648.1 - 0.048 12.9 0.0 0.13 11.5 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 ETS79648.1 - 0.052 13.5 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase KAP_NTPase PF07693.14 ETS79648.1 - 0.055 12.7 0.2 1.1 8.4 0.2 2.3 1 1 0 1 1 1 0 KAP family P-loop domain DUF2383 PF09537.10 ETS79648.1 - 0.087 13.2 1.3 1.4 9.3 0.2 3.4 4 0 0 4 4 2 0 Domain of unknown function (DUF2383) AAA_28 PF13521.6 ETS79648.1 - 0.11 12.8 0.0 4.3 7.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ETS79648.1 - 0.11 12.9 0.0 0.36 11.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 ETS79648.1 - 0.19 11.6 0.2 0.88 9.5 0.0 2.2 3 0 0 3 3 2 0 NTPase SMC_N PF02463.19 ETS79648.1 - 0.21 11.0 0.0 4.3 6.7 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ETS79648.1 - 0.58 10.6 0.0 0.58 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF1366 PF07104.11 ETS79648.1 - 6.2 6.6 5.4 2.2 8.0 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) MFS_1 PF07690.16 ETS79649.1 - 1.2e-15 57.3 19.4 1.7e-15 56.8 19.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ETS79649.1 - 1.3e-05 24.9 2.3 1.3e-05 24.9 2.3 3.1 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 ETS79649.1 - 0.013 14.4 12.3 0.035 13.0 11.7 1.9 1 1 0 1 1 1 0 Sugar (and other) transporter Fungal_trans PF04082.18 ETS79650.1 - 6.3e-28 97.5 2.3 8.9e-28 97.1 0.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS79650.1 - 4.6e-06 26.7 9.3 4.6e-06 26.7 9.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_2 PF04909.14 ETS79651.1 - 2.3e-20 73.5 0.0 2.9e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Memo PF01875.17 ETS79651.1 - 0.13 11.4 0.0 0.29 10.2 0.0 1.5 2 0 0 2 2 2 0 Memo-like protein Sugar_tr PF00083.24 ETS79652.1 - 4.4e-82 276.3 20.3 5.1e-82 276.1 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS79652.1 - 2.9e-18 65.9 13.8 2.9e-18 65.9 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PrpF PF04303.13 ETS79653.1 - 3.8e-107 358.5 0.1 4.4e-107 358.3 0.1 1.0 1 0 0 1 1 1 1 PrpF protein Pro_racemase PF05544.11 ETS79653.1 - 0.057 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Proline racemase Aconitase PF00330.20 ETS79654.1 - 1.4e-64 218.8 0.0 1.9e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ETS79654.1 - 9.4e-43 145.7 0.0 1.4e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Ferritin PF00210.24 ETS79654.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like domain Aconitase PF00330.20 ETS79655.1 - 3.2e-52 178.1 0.0 3.7e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Mito_carr PF00153.27 ETS79656.1 - 2.8e-23 81.7 4.7 1.2e-11 44.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein NAD_binding_10 PF13460.6 ETS79657.1 - 5.6e-25 88.3 0.0 6.9e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS79657.1 - 2.7e-08 33.6 0.0 3.5e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ETS79657.1 - 5e-08 32.7 0.0 7.8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS79657.1 - 1.2e-05 24.5 0.0 1.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 ETS79657.1 - 0.0013 19.0 0.0 0.064 13.5 0.0 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 ETS79657.1 - 0.0014 17.8 0.1 0.085 11.9 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain p450 PF00067.22 ETS79659.1 - 1.8e-22 79.7 0.0 2.3e-21 76.1 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 TrkH PF02386.16 ETS79660.1 - 1.6e-87 294.1 1.9 5.5e-83 279.1 0.1 2.2 2 0 0 2 2 2 2 Cation transport protein DUF2182 PF09948.9 ETS79660.1 - 0.9 9.4 8.6 0.036 14.0 2.1 1.9 2 0 0 2 2 2 0 Predicted metal-binding integral membrane protein (DUF2182) TRAM1 PF08390.11 ETS79660.1 - 1.7 8.4 5.1 0.19 11.4 0.2 2.0 2 0 0 2 2 2 0 TRAM1-like protein AMP-binding PF00501.28 ETS79661.1 - 2.3e-145 484.4 0.0 6.9e-76 255.5 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 ETS79661.1 - 7.8e-142 473.2 1.0 1.8e-71 241.2 0.0 3.1 2 1 1 3 3 3 3 Condensation domain PP-binding PF00550.25 ETS79661.1 - 1.5e-28 98.9 0.0 7.1e-13 48.7 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 ETS79661.1 - 2.9e-25 89.7 0.0 6.2e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain AMP-binding_C PF13193.6 ETS79661.1 - 8.1e-15 55.6 0.0 1.4e-07 32.4 0.0 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 ETS79662.1 - 5.9e-72 242.2 0.0 1e-71 241.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS79662.1 - 3.6e-37 128.1 0.0 6.3e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS79662.1 - 0.0017 17.8 0.0 0.004 16.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 ETS79662.1 - 0.0039 16.6 0.0 0.0087 15.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ETS79662.1 - 0.24 10.1 0.0 0.24 10.1 0.0 2.6 3 0 0 3 3 3 0 Fungal protein kinase Haspin_kinase PF12330.8 ETS79662.1 - 0.25 10.2 0.1 0.64 8.9 0.1 1.5 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 ETS79662.1 - 4.7 6.8 6.3 6.2 6.4 0.0 2.4 2 0 0 2 2 2 0 RIO1 family Homeodomain PF00046.29 ETS79663.1 - 7.1e-18 64.2 3.0 1.5e-17 63.2 3.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ETS79663.1 - 0.0043 16.9 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Herpes_LP PF03363.13 ETS79663.1 - 0.071 12.9 5.4 0.025 14.4 1.8 2.1 2 0 0 2 2 2 0 Herpesvirus leader protein 3HCDH_N PF02737.18 ETS79664.1 - 1.9e-52 177.7 1.5 2.6e-52 177.3 1.5 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ETS79664.1 - 6.5e-33 113.2 0.0 1.3e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 ETS79664.1 - 1.7e-05 25.1 0.1 3.5e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 ETS79664.1 - 0.00019 21.7 0.4 0.00063 20.0 0.4 2.0 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.24 ETS79664.1 - 0.0013 18.3 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS79664.1 - 0.012 14.8 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ETS79664.1 - 0.025 13.9 0.4 0.056 12.7 0.4 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ETS79664.1 - 0.031 13.6 0.2 0.079 12.3 0.1 1.6 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 ETS79664.1 - 0.15 12.7 0.1 0.34 11.5 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 ETS79664.1 - 2.4 8.8 5.1 5.1 7.7 3.1 2.5 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TIMELESS PF04821.14 ETS79665.1 - 3.1e-84 282.5 0.3 3.1e-84 282.5 0.3 2.6 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.13 ETS79665.1 - 2.7e-35 122.6 10.8 2.7e-35 122.6 10.8 3.3 2 1 1 3 3 3 1 Timeless protein C terminal region 2-Hacid_dh_C PF02826.19 ETS79666.1 - 9.2e-50 168.5 0.0 1.5e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS79666.1 - 8.3e-16 57.9 0.0 1.4e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain PBP PF01161.20 ETS79667.1 - 1.5e-16 60.9 0.1 2.7e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pyr_redox_2 PF07992.14 ETS79668.1 - 3.8e-29 101.8 0.1 4.7e-29 101.5 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS79668.1 - 3.9e-10 40.2 0.4 3.3e-07 30.8 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS79668.1 - 1.6e-07 31.5 0.4 0.068 13.2 0.0 3.3 2 1 1 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ETS79668.1 - 1.5e-06 27.5 0.4 0.0041 16.2 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 ETS79668.1 - 0.00096 18.8 4.4 0.57 9.7 0.0 3.6 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 ETS79668.1 - 0.0016 17.7 0.0 0.1 11.7 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 ETS79668.1 - 0.037 12.9 0.8 3.2 6.5 0.4 2.2 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.18 ETS79668.1 - 0.062 13.6 0.2 7.6 6.8 0.1 2.7 3 0 0 3 3 3 0 TrkA-N domain CENP-S PF15630.6 ETS79669.1 - 2.6e-34 117.5 0.0 3.4e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ETS79669.1 - 1.4e-08 34.8 0.1 1.6e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 ETS79669.1 - 0.1 12.7 0.1 0.13 12.3 0.1 1.3 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit PGA2 PF07543.12 ETS79670.1 - 2.1e-40 137.9 1.7 2.4e-40 137.7 1.7 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 CDC27 PF09507.10 ETS79670.1 - 0.028 13.8 3.9 0.024 14.0 3.2 1.3 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-C3HC4_3 PF13920.6 ETS79671.1 - 1 9.2 4.2 9.8 6.1 0.4 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Malic_M PF03949.15 ETS79673.1 - 3e-93 311.8 0.0 4.3e-93 311.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 ETS79673.1 - 2.9e-68 229.3 0.0 4.7e-68 228.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain MFS_1 PF07690.16 ETS79674.1 - 3e-45 154.7 38.9 3e-45 154.7 38.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CclA_1 PF16942.5 ETS79674.1 - 0.054 13.8 0.4 0.054 13.8 0.4 2.4 3 0 0 3 3 3 0 Putative cyclic bacteriocin FAD_binding_4 PF01565.23 ETS79676.1 - 7.2e-27 93.8 1.4 1.2e-26 93.1 1.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS79676.1 - 0.00039 20.5 0.1 0.00087 19.3 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Arginosuc_synth PF00764.19 ETS79677.1 - 9.8e-137 456.4 0.0 1.1e-136 456.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 ETS79677.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Fungal_trans_2 PF11951.8 ETS79678.1 - 1.7e-08 33.7 2.7 2.3e-08 33.3 2.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidase PF01425.21 ETS79679.1 - 1.6e-86 291.1 0.0 3.6e-86 289.9 0.0 1.5 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 ETS79680.1 - 1e-27 97.0 33.1 1e-27 97.0 33.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.24 ETS79681.1 - 9.4e-30 104.4 0.0 1.2e-29 104.1 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS79681.1 - 0.054 13.7 0.8 0.13 12.5 0.8 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Aldo_ket_red PF00248.21 ETS79682.1 - 1.2e-49 169.1 0.0 1.4e-49 168.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1190 PF06693.11 ETS79682.1 - 0.14 12.5 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) GAS2 PF02187.17 ETS79683.1 - 3.1e-06 27.2 0.0 6.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain SPW PF03779.14 ETS79685.1 - 0.16 11.5 0.4 0.16 11.5 0.4 4.0 3 1 1 4 4 4 0 SPW repeat Spc29 PF17082.5 ETS79686.1 - 0.00051 20.0 0.2 0.00052 19.9 0.2 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 FAD_binding_3 PF01494.19 ETS79687.1 - 7.8e-24 84.6 0.6 4.3e-23 82.1 0.6 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ETS79687.1 - 2.1e-05 23.9 0.5 0.0077 15.5 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS79687.1 - 5.2e-05 22.6 0.0 0.034 13.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS79687.1 - 0.00015 21.4 1.4 0.004 16.8 0.7 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS79687.1 - 0.00055 20.1 0.1 0.0017 18.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ETS79687.1 - 0.0021 17.4 0.1 0.16 11.2 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 ETS79687.1 - 0.016 14.1 1.0 0.041 12.7 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 ETS79687.1 - 0.038 13.2 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HET PF06985.11 ETS79688.1 - 6.2e-36 123.9 0.2 9.9e-36 123.3 0.2 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BAR PF03114.18 ETS79689.1 - 1.5e-49 168.8 7.8 2e-49 168.4 7.8 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 ETS79689.1 - 6.3e-06 25.5 6.9 1.1e-05 24.8 6.9 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF3086 PF11285.8 ETS79689.1 - 0.019 14.1 0.4 0.028 13.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) DUF2335 PF10097.9 ETS79689.1 - 0.15 12.0 3.0 6.9 6.7 0.6 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) UPF0242 PF06785.11 ETS79689.1 - 3.4 7.7 7.7 0.92 9.6 4.6 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus 5_nucleotid_C PF02872.18 ETS79690.1 - 1.4e-31 109.8 0.0 3.3e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 ETS79690.1 - 4.5e-10 40.4 1.1 1.2e-09 38.9 0.4 2.1 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.6 ETS79690.1 - 0.0097 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 YmdB-like protein PGA_cap PF09587.10 ETS79690.1 - 0.05 13.0 0.1 0.15 11.4 0.0 1.5 1 1 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap MFS_1 PF07690.16 ETS79691.1 - 7.6e-31 107.3 25.6 7.6e-31 107.3 25.6 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF983 PF06170.12 ETS79691.1 - 0.074 13.5 4.4 0.2 12.1 1.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DUF4387 PF14330.6 ETS79692.1 - 3.7e-33 114.1 0.0 7.3e-33 113.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 ETS79692.1 - 2.4e-07 29.8 0.0 3.4e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA UBA_6 PF18039.1 ETS79692.1 - 0.048 13.6 0.1 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 UBA-like domain Fungal_trans PF04082.18 ETS79693.1 - 5.5e-12 45.3 1.2 9.4e-12 44.5 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_N_assoc PF13823.6 ETS79694.1 - 0.0006 19.7 0.3 0.0012 18.8 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_N PF08240.12 ETS79695.1 - 2.1e-17 63.0 0.9 3.5e-17 62.3 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS79695.1 - 1.7e-14 53.9 0.0 2.8e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS79695.1 - 7.7e-06 25.5 0.0 1.7e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ETS79695.1 - 0.0016 19.5 0.0 0.003 18.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ETS79695.1 - 0.0078 15.5 0.0 0.019 14.2 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lactamase_B PF00753.27 ETS79696.1 - 4.1e-11 43.3 0.2 8.5e-11 42.2 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS79696.1 - 0.00033 20.2 0.3 0.00082 18.9 0.3 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Sugar_tr PF00083.24 ETS79698.1 - 1.8e-82 277.6 27.3 2.2e-82 277.3 27.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS79698.1 - 4.2e-25 88.4 49.0 6.3e-19 68.1 26.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ETS79698.1 - 0.018 13.3 10.5 0.019 13.3 8.8 2.0 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CFEM PF05730.11 ETS79699.1 - 5.7e-10 39.1 9.7 9.5e-10 38.4 9.7 1.3 1 0 0 1 1 1 1 CFEM domain Activator_LAG-3 PF11498.8 ETS79699.1 - 0.095 11.7 29.9 0.16 10.9 29.9 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SLC12 PF03522.15 ETS79699.1 - 0.16 11.0 5.6 0.22 10.5 5.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Spem1 PF15670.5 ETS79699.1 - 1.2 8.7 11.9 2.5 7.6 11.9 1.5 1 0 0 1 1 1 0 Spermatid maturation protein 1 RR_TM4-6 PF06459.12 ETS79699.1 - 2.9 7.7 12.8 4.2 7.1 12.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 ETS79699.1 - 4.7 6.1 15.7 6.3 5.6 15.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 ETS79699.1 - 7.8 6.7 8.3 13 5.9 8.3 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 ETS79699.1 - 8.6 4.5 14.2 12 4.0 14.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4770 PF15994.5 ETS79699.1 - 9.2 6.5 15.8 17 5.6 15.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) SprA-related PF12118.8 ETS79699.1 - 9.9 5.2 23.8 15 4.6 23.8 1.1 1 0 0 1 1 1 0 SprA-related family MT0933_antitox PF14013.6 ETS79700.1 - 0.034 14.4 6.9 0.41 11.0 4.9 2.5 2 1 0 2 2 2 0 MT0933-like antitoxin protein PGA2 PF07543.12 ETS79700.1 - 0.34 10.9 3.7 0.52 10.3 3.7 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 LRR_6 PF13516.6 ETS79701.1 - 3e-19 67.4 19.7 0.37 11.0 0.0 13.6 13 1 1 14 14 14 7 Leucine Rich repeat F-box-like PF12937.7 ETS79701.1 - 1.7e-12 47.0 3.7 3.1e-12 46.2 0.6 2.6 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ETS79701.1 - 1.1e-11 44.7 13.8 0.22 12.0 0.2 8.0 5 1 1 7 7 7 6 Leucine Rich repeats (2 copies) F-box PF00646.33 ETS79701.1 - 0.00041 20.1 0.3 0.0017 18.2 0.3 2.0 1 0 0 1 1 1 1 F-box domain DUF1699 PF08004.11 ETS79701.1 - 0.0076 15.9 0.8 21 4.8 0.0 4.2 3 1 1 4 4 4 1 Protein of unknown function (DUF1699) Chalcone_2 PF16035.5 ETS79702.1 - 2.6e-75 252.7 0.0 3.5e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 ETS79702.1 - 0.0021 18.2 0.1 0.086 13.0 0.0 2.3 2 0 0 2 2 2 1 Chalcone isomerase-like Peptidase_S10 PF00450.22 ETS79703.1 - 1e-97 328.2 1.4 1.3e-97 327.9 1.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase TMEM154 PF15102.6 ETS79704.1 - 0.001 19.0 0.1 0.0021 18.0 0.1 1.6 1 1 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.11 ETS79704.1 - 0.12 12.5 7.4 0.29 11.2 7.4 1.7 1 1 0 1 1 1 0 Podoplanin Nitrate_red_gam PF02665.14 ETS79704.1 - 0.14 11.7 0.0 0.31 10.5 0.0 1.6 2 0 0 2 2 2 0 Nitrate reductase gamma subunit Syndecan PF01034.20 ETS79704.1 - 0.19 11.7 0.1 0.35 10.8 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain DUF87 PF01935.17 ETS79705.1 - 0.0033 17.6 0.7 2.7 8.1 0.2 2.9 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_22 PF13401.6 ETS79705.1 - 0.012 15.9 0.5 1.6 9.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 ETS79705.1 - 0.031 13.6 0.0 0.074 12.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DarA_C PF18789.1 ETS79705.1 - 0.099 13.0 0.0 5.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Defence against restriction A C-terminal OTT_1508_deam PF14441.6 ETS79706.1 - 1.6e-17 63.2 1.9 3.4e-17 62.2 1.9 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase Glutaredoxin PF00462.24 ETS79707.1 - 5.6e-18 64.9 0.0 8e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin PF00085.20 ETS79707.1 - 0.0025 17.8 0.0 0.0028 17.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.14 ETS79707.1 - 0.022 15.2 0.1 0.04 14.3 0.1 1.5 1 1 1 2 2 2 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 ETS79707.1 - 0.031 14.1 0.1 0.078 12.8 0.1 1.7 1 1 0 1 1 1 0 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 ETS79707.1 - 0.034 14.6 0.0 0.043 14.3 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain BAG PF02179.16 ETS79708.1 - 5.2e-20 71.7 0.2 1e-19 70.7 0.2 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 ETS79708.1 - 0.00013 21.6 0.0 0.0003 20.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 ETS79708.1 - 0.029 14.7 0.1 0.029 14.7 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 ETS79708.1 - 0.034 14.7 0.2 0.088 13.4 0.2 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ribosomal_L13 PF00572.18 ETS79709.1 - 7.6e-12 45.6 0.0 6.6e-10 39.3 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 DSBA PF01323.20 ETS79709.1 - 0.073 12.8 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain MFS_1 PF07690.16 ETS79710.1 - 2.3e-32 112.3 58.9 1.1e-31 110.1 54.5 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 ETS79711.1 - 3.2e-39 134.8 4.3 5.1e-39 134.2 4.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Bac_rhamnosid6H PF17389.2 ETS79712.1 - 1.3e-09 37.8 0.2 2.2e-08 33.7 0.1 2.1 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 ETS79712.1 - 0.0021 16.9 0.1 0.0034 16.3 0.1 1.2 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid_C PF17390.2 ETS79712.1 - 0.0027 17.5 0.0 0.0059 16.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Lactonase PF10282.9 ETS79714.1 - 3.7e-90 302.7 0.6 4.6e-90 302.3 0.6 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller FAD_binding_4 PF01565.23 ETS79715.1 - 1.8e-25 89.3 5.5 7.6e-24 84.0 5.5 2.8 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.12 ETS79715.1 - 2.3e-12 46.8 0.1 5.2e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like AA_permease PF00324.21 ETS79716.1 - 2.2e-119 399.2 42.0 2.8e-119 398.9 42.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS79716.1 - 6.4e-22 78.0 44.2 8.5e-22 77.6 44.2 1.1 1 0 0 1 1 1 1 Amino acid permease PLDc_2 PF13091.6 ETS79717.1 - 4.7e-18 65.4 0.0 2.5e-12 46.8 0.1 3.3 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.22 ETS79717.1 - 0.0018 18.4 0.0 0.2 11.9 0.0 2.6 2 0 0 2 2 2 1 Phospholipase D Active site motif Regulator_TrmB PF11495.8 ETS79717.1 - 0.014 14.6 0.2 0.69 9.1 0.0 2.7 3 0 0 3 3 3 0 Archaeal transcriptional regulator TrmB DUF3102 PF11300.8 ETS79717.1 - 0.18 12.0 0.0 0.43 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3102) Fungal_trans PF04082.18 ETS79718.1 - 0.012 14.6 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain SPOR PF05036.13 ETS79718.1 - 0.16 12.4 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 Sporulation related domain DUF2293 PF10056.9 ETS79719.1 - 6.5e-27 93.6 0.3 1.5e-26 92.4 0.3 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) CsbD PF05532.12 ETS79720.1 - 1.8e-20 72.5 18.7 4.3e-11 42.5 5.7 3.2 2 1 1 3 3 3 3 CsbD-like LIP PF03583.14 ETS79721.1 - 0.071 12.4 3.3 0.96 8.7 0.2 2.3 2 0 0 2 2 2 0 Secretory lipase Glug PF07581.12 ETS79721.1 - 0.097 13.1 1.3 0.49 10.9 1.3 2.3 1 0 0 1 1 1 0 The GLUG motif CoA_binding_3 PF13727.6 ETS79722.1 - 5.2 7.1 16.1 0.24 11.4 2.5 3.7 3 0 0 3 3 3 0 CoA-binding domain Amidase PF01425.21 ETS79723.1 - 3.3e-100 336.2 0.0 4.3e-100 335.8 0.0 1.1 1 0 0 1 1 1 1 Amidase Connexin50 PF03509.14 ETS79723.1 - 0.1 13.4 0.2 0.94 10.3 0.0 2.2 2 0 0 2 2 2 0 Gap junction alpha-8 protein (Cx50) MFS_1 PF07690.16 ETS79724.1 - 1.2e-29 103.4 28.6 1.2e-29 103.4 28.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3397 PF11877.8 ETS79724.1 - 9.7 6.4 14.8 33 4.7 2.9 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3397) Fungal_trans PF04082.18 ETS79725.1 - 1.2e-24 86.8 1.4 2.4e-24 85.8 1.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS79725.1 - 1.5e-08 34.6 8.5 1.5e-08 34.6 8.5 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRCB PF02537.15 ETS79726.1 - 4.2e-35 119.9 13.1 4.7e-22 78.1 6.6 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) DctQ PF04290.12 ETS79726.1 - 1.4 8.9 9.9 0.018 14.9 2.1 1.9 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component adh_short_C2 PF13561.6 ETS79727.1 - 3e-61 207.0 1.2 3.7e-61 206.7 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS79727.1 - 3.6e-41 140.8 1.4 4.4e-41 140.5 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS79727.1 - 4.1e-08 33.3 0.2 6.1e-08 32.8 0.2 1.2 1 0 0 1 1 1 1 KR domain SWIRM-assoc_3 PF16498.5 ETS79727.1 - 0.33 11.2 1.2 3.8 7.8 0.2 2.7 3 0 0 3 3 3 0 SWIRM-associated domain at the C-terminal ILVD_EDD PF00920.21 ETS79728.1 - 8.4e-157 522.9 0.3 9.6e-157 522.7 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family MFS_1 PF07690.16 ETS79729.1 - 3.8e-21 75.4 36.6 2.2e-20 72.9 35.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.6 ETS79729.1 - 2.3 8.8 4.5 10 6.7 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) SGL PF08450.12 ETS79730.1 - 3.3e-35 121.8 0.0 3.8e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 ETS79730.1 - 4.8e-06 26.6 0.0 0.68 10.1 0.0 3.4 1 1 2 3 3 3 2 Strictosidine synthase NHL PF01436.21 ETS79730.1 - 0.009 16.0 0.1 17 5.7 0.0 4.8 6 0 0 6 6 6 1 NHL repeat SBBP PF06739.11 ETS79730.1 - 0.0093 15.9 0.6 0.05 13.6 0.2 2.4 3 0 0 3 3 3 1 Beta-propeller repeat Arylesterase PF01731.20 ETS79730.1 - 0.12 12.6 0.0 1.8 8.8 0.0 2.7 3 0 0 3 3 3 0 Arylesterase MFS_1 PF07690.16 ETS79731.1 - 1.5e-43 149.1 45.3 2.5e-43 148.3 39.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.7 ETS79733.1 - 1.1e-17 65.4 3.9 7.4e-17 62.7 3.9 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS79733.1 - 5.2e-07 29.6 0.0 5.3e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS79733.1 - 0.0057 16.0 0.1 0.052 12.8 0.0 2.4 3 0 0 3 3 3 1 Serine aminopeptidase, S33 DUF3089 PF11288.8 ETS79733.1 - 0.018 14.6 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF2974 PF11187.8 ETS79733.1 - 0.034 13.7 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 ETS79733.1 - 0.098 12.4 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Putative_PNPOx PF01243.20 ETS79734.1 - 7.6e-19 67.7 0.0 1.4e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 ETS79734.1 - 6e-15 55.0 1.1 1e-14 54.3 1.1 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 ETS79734.1 - 3.8e-07 30.7 0.0 8e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 ETS79734.1 - 0.02 14.5 0.0 0.057 13.0 0.0 1.7 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase like CDH-cyt PF16010.5 ETS79735.1 - 2e-45 154.7 0.0 2.5e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase CRAL_TRIO PF00650.20 ETS79736.1 - 5.8e-24 84.6 0.0 8.3e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ETS79736.1 - 5.9e-07 29.6 0.0 1.3e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SnoaL PF07366.12 ETS79737.1 - 2e-13 50.2 0.0 2.4e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 ETS79737.1 - 0.00043 20.9 0.0 0.00055 20.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ETS79738.1 - 3.1e-05 23.8 0.1 9.7e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 ETS79738.1 - 0.0043 17.7 0.0 0.0073 16.9 0.0 1.3 1 1 0 1 1 1 1 SnoaL-like domain p450 PF00067.22 ETS79739.1 - 6.3e-64 216.4 0.0 7.7e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GCD14 PF08704.10 ETS79740.1 - 8.3e-61 205.8 0.1 7.2e-59 199.4 0.1 3.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit DUF3759 PF12585.8 ETS79741.1 - 2.1e-39 133.4 5.9 2.6e-39 133.2 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) PAF-AH_p_II PF03403.13 ETS79742.1 - 5.5e-42 143.6 0.0 3.4e-37 127.8 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ETS79742.1 - 0.00021 20.3 0.0 0.00046 19.2 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 ETS79742.1 - 0.02 13.9 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase DLH PF01738.18 ETS79742.1 - 0.044 13.3 0.0 0.099 12.2 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 ETS79742.1 - 0.059 12.6 0.1 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_M18 PF02127.15 ETS79743.1 - 3.1e-127 424.9 0.0 3.6e-127 424.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Glyco_hydro_76 PF03663.14 ETS79744.1 - 2.5e-133 445.2 11.3 2.9e-133 444.9 11.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 ETS79744.1 - 0.08 12.0 6.3 1.1 8.2 0.3 3.1 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 Transferase PF02458.15 ETS79745.1 - 1.5e-19 70.0 0.0 1.6e-15 56.7 0.0 2.1 2 0 0 2 2 2 2 Transferase family Aldo_ket_red PF00248.21 ETS79746.1 - 1.9e-61 207.8 0.0 2.2e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TAF6_C PF07571.13 ETS79747.1 - 1.5e-24 86.2 0.0 3.5e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 ETS79747.1 - 1.8e-22 79.2 0.0 3.3e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 ETS79747.1 - 0.001 19.4 0.1 0.0016 18.8 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ETS79747.1 - 0.011 16.0 0.0 0.03 14.6 0.0 1.7 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIIE_beta PF02186.15 ETS79747.1 - 0.029 14.7 0.0 2.6 8.4 0.0 2.5 2 0 0 2 2 2 0 TFIIE beta subunit core domain Sdh_cyt PF01127.22 ETS79748.1 - 4.3e-16 59.0 2.6 6.6e-16 58.4 2.6 1.3 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit MFS_1 PF07690.16 ETS79749.1 - 1.1e-32 113.4 27.2 1.1e-32 113.4 27.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Cupin_2 PF07883.11 ETS79750.1 - 0.027 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Zn_clus PF00172.18 ETS79751.1 - 0.0019 18.3 8.5 0.0034 17.5 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_dh PF01070.18 ETS79752.1 - 3.4e-112 374.9 0.0 4.1e-112 374.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ETS79752.1 - 1.1e-18 67.1 0.0 2.1e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 ETS79752.1 - 9.4e-05 21.7 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 ETS79752.1 - 0.00016 20.8 0.2 0.00046 19.3 0.1 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 ETS79752.1 - 0.0003 20.3 0.0 0.00049 19.6 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 ETS79752.1 - 0.033 13.5 0.0 0.51 9.6 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG F-box PF00646.33 ETS79753.1 - 3e-09 36.5 1.2 7e-09 35.3 1.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ETS79753.1 - 8.7e-05 22.3 4.4 0.00018 21.3 4.4 1.6 1 0 0 1 1 1 1 F-box-like DUF5422 PF17459.2 ETS79753.1 - 0.009 16.2 0.1 0.015 15.4 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5422) CopK PF11525.8 ETS79753.1 - 0.039 13.6 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 Copper resistance protein K Methyltransf_25 PF13649.6 ETS79754.1 - 1.5e-10 41.6 0.0 3.8e-10 40.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS79754.1 - 9.9e-09 35.7 0.0 2.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS79754.1 - 2.4e-07 30.3 0.0 3.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ETS79754.1 - 9.2e-06 26.3 0.0 1.6e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS79754.1 - 9.9e-05 22.2 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_20 PF12147.8 ETS79754.1 - 0.088 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Tannase PF07519.11 ETS79755.1 - 4.1e-96 322.7 2.9 8.1e-96 321.8 2.9 1.4 1 1 0 1 1 1 1 Tannase and feruloyl esterase Cofilin_ADF PF00241.20 ETS79756.1 - 2.3e-24 85.5 0.0 2.6e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Adaptin_binding PF10199.9 ETS79757.1 - 1.8e-14 54.4 1.8 4.4e-14 53.1 1.8 1.7 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Homeodomain PF00046.29 ETS79758.1 - 2.4e-19 68.9 4.5 4.8e-19 68.0 4.5 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ETS79758.1 - 0.0015 18.4 0.6 0.0044 16.9 0.6 1.9 1 0 0 1 1 1 1 Homeobox KN domain NAM-associated PF14303.6 ETS79758.1 - 0.28 11.9 7.5 0.56 10.9 7.5 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain PhoLip_ATPase_C PF16212.5 ETS79759.1 - 1.5e-63 214.9 20.4 1.5e-63 214.9 20.4 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ETS79759.1 - 1.1e-25 89.1 4.7 1.5e-24 85.5 1.6 3.0 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 ETS79759.1 - 1.2e-13 51.8 0.8 1.4e-06 28.8 0.2 3.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ETS79759.1 - 3.2e-11 43.1 0.0 7.5e-10 38.8 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 ETS79759.1 - 1.2e-10 41.3 0.0 1.2e-10 41.3 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ETS79759.1 - 0.0031 17.3 0.0 0.0089 15.8 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CoatB PF10389.9 ETS79759.1 - 0.97 9.3 3.4 12 5.9 0.3 2.7 2 0 0 2 2 2 0 Bacteriophage coat protein B HlyIII PF03006.20 ETS79760.1 - 8.3e-13 48.6 0.4 9.7e-13 48.3 0.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related MFS_1 PF07690.16 ETS79761.1 - 1.1e-17 64.0 23.1 1.6e-17 63.5 23.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2631 PF10939.8 ETS79761.1 - 0.12 12.2 0.0 0.47 10.3 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2631) PMP1_2 PF08114.11 ETS79761.1 - 0.46 10.3 3.3 12 5.7 0.2 2.7 2 0 0 2 2 2 0 ATPase proteolipid family Sulfatase PF00884.23 ETS79762.1 - 2.5e-61 207.8 1.0 3.1e-61 207.5 1.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 ETS79762.1 - 0.0029 17.3 2.6 0.77 9.3 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.16 ETS79763.1 - 2.3e-40 138.6 41.3 2.3e-40 138.6 41.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS79763.1 - 5.2e-11 42.1 21.2 3.3e-06 26.2 0.7 3.2 3 0 0 3 3 3 3 Sugar (and other) transporter DUF4094 PF13334.6 ETS79763.1 - 0.029 14.8 5.5 0.13 12.7 0.2 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4094) Phage_holin_3_2 PF04550.12 ETS79763.1 - 0.12 12.9 4.5 0.22 12.1 0.6 3.1 2 1 0 2 2 2 0 Phage holin family 2 OATP PF03137.20 ETS79763.1 - 4.7 5.4 12.2 0.82 7.9 1.4 2.9 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 ETS79764.1 - 2.2e-35 122.3 38.1 2.2e-35 122.3 38.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS79764.1 - 2.9e-13 49.5 8.3 2.9e-13 49.5 8.3 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter Sugar_tr PF00083.24 ETS79765.1 - 3.4e-56 191.0 31.7 3.9e-56 190.8 31.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS79765.1 - 2.2e-12 46.6 45.1 6.4e-12 45.1 40.0 2.8 1 1 2 3 3 3 1 Major Facilitator Superfamily zf-RNPHF PF08080.12 ETS79765.1 - 0.056 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 RNPHF zinc finger ATP1G1_PLM_MAT8 PF02038.16 ETS79765.1 - 0.37 10.3 7.7 0.53 9.8 0.8 3.2 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family Bac_rhamnosid6H PF17389.2 ETS79766.1 - 8.1e-24 84.5 0.1 1.1e-23 84.0 0.1 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 ETS79766.1 - 0.001 19.0 0.2 0.0087 15.9 0.2 2.3 1 1 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_2_N PF02837.18 ETS79766.1 - 0.011 15.6 0.1 0.18 11.7 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain NMT1 PF09084.11 ETS79767.1 - 1.2e-06 28.6 0.0 1.4e-05 25.2 0.0 2.0 1 1 1 2 2 2 1 NMT1/THI5 like GST_C_3 PF14497.6 ETS79767.1 - 0.063 13.5 0.1 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain FLILHELTA PF10306.9 ETS79768.1 - 8.2e-21 74.2 0.0 1.8e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA NDK PF00334.19 ETS79769.1 - 6.9e-53 178.3 0.0 1.1e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.26 ETS79770.1 - 1.4e-140 469.4 3.9 2e-140 468.9 3.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 ETS79770.1 - 5.4e-22 77.9 0.3 2.1e-21 76.0 0.1 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 ETS79770.1 - 2.7e-06 27.5 0.8 1.6e-05 25.1 0.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) 4HBT_3 PF13622.6 ETS79771.1 - 8.1e-21 75.4 0.1 1.2e-20 74.9 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily DER1 PF04511.15 ETS79772.1 - 1.5e-18 67.5 6.5 1.7e-18 67.2 6.5 1.0 1 0 0 1 1 1 1 Der1-like family CN_hydrolase PF00795.22 ETS79774.1 - 7.6e-16 58.2 0.0 7.1e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase RCDG1 PF15725.5 ETS79775.1 - 7.3 7.1 7.0 6.6 7.2 0.5 3.0 3 0 0 3 3 3 0 Renal cancer differentiation gene 1 protein DKCLD PF08068.12 ETS79776.1 - 2e-30 104.7 0.1 2.8e-29 101.0 0.1 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 ETS79776.1 - 1.1e-22 81.0 3.7 1.5e-20 74.1 0.2 3.5 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 ETS79776.1 - 1e-21 76.8 1.3 1.9e-21 75.9 1.3 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 ETS79776.1 - 1.4e-20 73.0 1.1 2.7e-20 72.1 1.1 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 ETS79776.1 - 0.0066 16.7 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain Med19 PF10278.9 ETS79776.1 - 1 9.3 9.6 1.8 8.5 9.6 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Glyco_hydro_43 PF04616.14 ETS79777.1 - 3.2e-30 105.4 0.0 5e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 SKG6 PF08693.10 ETS79778.1 - 0.0017 17.7 0.3 0.0017 17.7 0.3 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 ETS79778.1 - 0.006 16.7 0.2 0.048 13.8 0.0 2.2 2 0 0 2 2 2 1 Podoplanin CD34_antigen PF06365.12 ETS79778.1 - 0.055 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family ArgJ PF01960.18 ETS79779.1 - 8.9e-152 505.2 0.5 1e-151 505.0 0.5 1.0 1 0 0 1 1 1 1 ArgJ family Rep_fac_C PF08542.11 ETS79780.1 - 4.2e-24 84.8 0.0 1.1e-23 83.4 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 ETS79780.1 - 3.5e-12 46.4 0.0 1.2e-08 35.0 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 ETS79780.1 - 1.8e-11 44.6 0.0 3.3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ETS79780.1 - 5.7e-07 29.6 0.0 1.5e-06 28.3 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS79780.1 - 2.6e-06 27.9 0.0 0.00014 22.3 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS79780.1 - 9.1e-05 22.8 0.1 0.16 12.3 0.0 2.4 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 ETS79780.1 - 0.0001 22.1 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 ETS79780.1 - 0.00021 21.1 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 ETS79780.1 - 0.00024 21.0 0.0 0.00056 19.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 ETS79780.1 - 0.0021 17.9 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 ETS79780.1 - 0.0025 17.7 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 ETS79780.1 - 0.0027 17.1 0.0 0.026 13.9 0.0 2.2 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI MeaB PF03308.16 ETS79780.1 - 0.0053 15.8 0.0 0.0097 14.9 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_assoc_2 PF16193.5 ETS79780.1 - 0.0054 17.0 0.0 0.019 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_5 PF07728.14 ETS79780.1 - 0.0089 16.0 0.0 0.048 13.6 0.0 2.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 ETS79780.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 ETS79780.1 - 0.012 15.4 0.1 0.35 10.6 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase TniB PF05621.11 ETS79780.1 - 0.012 15.0 0.0 2.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 ETS79780.1 - 0.017 14.9 0.0 0.066 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ETS79780.1 - 0.018 15.0 0.2 0.066 13.1 0.1 2.0 1 1 1 2 2 2 0 NTPase KTI12 PF08433.10 ETS79780.1 - 0.018 14.5 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_19 PF13245.6 ETS79780.1 - 0.023 15.0 0.1 0.08 13.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ETS79780.1 - 0.069 12.9 0.1 0.24 11.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ETS79780.1 - 0.08 12.5 0.0 0.75 9.3 0.1 2.1 2 1 1 3 3 3 0 AAA domain DNA_pol3_gamma3 PF12169.8 ETS79780.1 - 0.09 12.7 0.2 1.4 8.9 0.0 2.7 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III Mito_carr PF00153.27 ETS79782.1 - 2.9e-17 62.4 0.0 8.8e-10 38.4 0.0 3.4 3 1 0 3 3 3 2 Mitochondrial carrier protein GFA PF04828.14 ETS79783.1 - 1.7e-09 37.9 0.9 3.4e-09 36.9 0.9 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme ORC2 PF04084.14 ETS79784.1 - 3.2e-118 394.4 0.0 4.5e-118 393.9 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 IFRD PF05004.13 ETS79784.1 - 2.5 7.1 6.9 5 6.1 6.9 1.5 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) DUF3381 PF11861.8 ETS79784.1 - 4.9 6.9 10.2 6.5 6.5 6.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) PPP4R2 PF09184.11 ETS79784.1 - 5.8 6.4 11.8 9.3 5.7 11.8 1.3 1 0 0 1 1 1 0 PPP4R2 PGP_phosphatase PF09419.10 ETS79785.1 - 1.5e-63 213.4 0.0 1.7e-63 213.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 ETS79785.1 - 2.8e-07 30.5 0.0 4.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like CutC PF03932.14 ETS79787.1 - 7.6e-35 120.2 0.0 2.3e-33 115.4 0.0 2.0 1 1 0 1 1 1 1 CutC family FMN_dh PF01070.18 ETS79787.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Glyco_hydro_18 PF00704.28 ETS79788.1 - 1.1e-72 245.4 0.3 1.4e-72 245.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ETS79788.1 - 0.00023 21.6 22.9 0.00023 21.6 22.9 2.3 2 1 1 3 3 3 1 Chitin recognition protein SAM_decarbox PF01536.16 ETS79789.1 - 8.5e-134 446.0 0.0 1.1e-133 445.7 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase ParA PF10609.9 ETS79790.1 - 1.6e-90 302.9 0.1 2e-90 302.5 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 ETS79790.1 - 5.4e-10 39.4 0.0 1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 ETS79790.1 - 3.8e-07 29.7 0.0 3.2e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 ETS79790.1 - 2.1e-05 24.5 0.2 0.00076 19.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 ETS79790.1 - 2.5e-05 23.6 0.5 5.2e-05 22.6 0.3 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 ETS79790.1 - 0.0014 17.7 0.4 0.0023 17.0 0.4 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 ETS79790.1 - 0.0039 16.8 0.1 0.0069 16.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 ETS79790.1 - 0.0077 15.7 0.2 0.021 14.3 0.2 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 ETS79790.1 - 0.094 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_26 PF13500.6 ETS79790.1 - 0.15 11.9 1.6 7.2 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ETS79790.1 - 0.18 11.7 1.9 0.32 10.9 1.2 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 ETS79790.1 - 0.25 11.7 0.8 0.63 10.4 0.8 1.6 1 0 0 1 1 1 0 AAA ATPase domain SUR7 PF06687.12 ETS79792.1 - 6.5 6.3 8.7 15 5.1 1.2 2.1 1 1 1 2 2 2 0 SUR7/PalI family HMGL-like PF00682.19 ETS79794.1 - 1.6e-73 247.5 0.8 2.4e-73 246.9 0.8 1.2 1 0 0 1 1 1 1 HMGL-like DUF4213 PF13938.6 ETS79794.1 - 0.063 13.5 0.0 2.8 8.2 0.0 2.9 3 0 0 3 3 3 0 Putative heavy-metal chelation Flavin_Reduct PF01613.18 ETS79795.1 - 7.9e-21 74.7 0.0 1.3e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Glyco_hydro_16 PF00722.21 ETS79796.1 - 3e-07 30.1 0.3 8.1e-07 28.7 0.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 FimH_man-bind PF09160.10 ETS79796.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 FimH, mannose binding Lactamase_B_4 PF13691.6 ETS79797.1 - 1.7e-26 91.6 0.3 4.4e-26 90.4 0.1 1.9 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 ETS79797.1 - 8.3e-14 51.6 1.0 2e-13 50.3 1.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ETS79797.1 - 0.0018 18.3 0.4 0.0046 17.0 0.4 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily FhuF PF06276.12 ETS79797.1 - 0.17 12.3 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter COesterase PF00135.28 ETS79798.1 - 8.1e-50 170.1 0.0 1e-49 169.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS79798.1 - 0.00069 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF4157 PF13699.6 ETS79798.1 - 0.15 12.3 0.2 0.33 11.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) T2SSK PF03934.13 ETS79798.1 - 0.15 11.4 0.3 3.8 6.8 0.1 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein K Glyco_hydro_11 PF00457.17 ETS79799.1 - 4.2e-80 267.6 22.5 4.9e-80 267.3 22.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 BA14K PF07886.11 ETS79799.1 - 4 7.4 6.0 4.9 7.1 1.2 2.5 2 0 0 2 2 2 0 BA14K-like protein Cation_ATPase_C PF00689.21 ETS79800.1 - 0.00045 20.0 7.2 0.00045 20.0 7.2 2.1 1 1 1 2 2 2 1 Cation transporting ATPase, C-terminus COX4 PF02936.14 ETS79800.1 - 0.015 15.3 0.1 0.043 13.8 0.1 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DUF5391 PF17369.2 ETS79800.1 - 0.1 12.6 0.1 0.1 12.6 0.1 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5391) COPI_assoc PF08507.10 ETS79800.1 - 5.8 7.0 14.3 0.88 9.6 7.7 2.7 3 1 0 3 3 3 0 COPI associated protein GST_N_2 PF13409.6 ETS79801.1 - 0.0015 18.8 0.1 0.0061 16.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ETS79801.1 - 0.066 13.6 0.0 0.33 11.4 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain VCBS PF13517.6 ETS79802.1 - 1.4e-29 102.4 58.2 9e-11 42.2 2.3 8.5 5 2 4 9 9 9 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 ETS79802.1 - 4.8e-15 56.4 0.8 1.2e-14 55.1 0.8 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.8 ETS79802.1 - 4e-10 39.3 7.8 0.44 9.9 0.0 6.8 6 1 1 7 7 7 4 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL PF00657.22 ETS79802.1 - 1e-07 32.1 0.1 1.8e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FG-GAP PF01839.23 ETS79802.1 - 0.0047 17.0 39.6 0.1 12.7 1.7 7.7 7 1 1 8 8 8 4 FG-GAP repeat Dockerin_1 PF00404.18 ETS79802.1 - 0.021 15.0 10.3 4.2 7.6 0.1 6.3 6 0 0 6 6 6 0 Dockerin type I domain DUF5505 PF17610.2 ETS79803.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5505) adh_short PF00106.25 ETS79804.1 - 8.5e-07 28.6 0.1 0.00031 20.3 0.1 2.6 2 1 0 2 2 2 2 short chain dehydrogenase Terpene_synth_C PF03936.16 ETS79805.1 - 5.4e-05 22.7 0.1 0.0001 21.8 0.1 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain HEPN_RES_NTD1 PF18870.1 ETS79805.1 - 0.13 12.4 0.2 0.42 10.8 0.2 1.8 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 DUF4618 PF15397.6 ETS79806.1 - 0.024 14.1 0.2 0.042 13.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Col_cuticle_N PF01484.17 ETS79806.1 - 0.086 12.9 0.0 0.31 11.1 0.0 2.0 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain HET PF06985.11 ETS79807.1 - 1.3e-34 119.6 0.3 2.1e-34 119.0 0.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 ETS79808.1 - 6.1e-44 150.5 0.0 7.7e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Stb3 PF10330.9 ETS79809.1 - 4.7e-37 125.9 0.0 7.4e-37 125.3 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein Topoisom_bac PF01131.20 ETS79810.1 - 1.8e-102 343.5 0.0 6.6e-97 325.1 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 ETS79810.1 - 1.4e-19 70.2 0.0 3.8e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 Toprim domain DUF1295 PF06966.12 ETS79811.1 - 1.1e-39 136.4 10.1 1.4e-39 136.0 10.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Crystall PF00030.19 ETS79811.1 - 0.078 13.2 0.3 2.2 8.5 0.2 2.5 2 0 0 2 2 2 0 Beta/Gamma crystallin DUF4149 PF13664.6 ETS79813.1 - 3.8e-23 81.7 2.1 2.8e-22 79.0 1.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Ku_PK_bind PF08785.11 ETS79814.1 - 1.7e-33 115.3 0.0 3.5e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 ETS79814.1 - 5e-30 104.7 0.0 1.2e-29 103.5 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 ETS79814.1 - 4.2e-12 46.3 0.0 1.1e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 ETS79814.1 - 0.02 15.1 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain MutS_III PF05192.18 ETS79814.1 - 0.05 13.8 0.1 0.14 12.4 0.1 1.7 1 0 0 1 1 1 0 MutS domain III Ku_C PF03730.14 ETS79814.1 - 0.087 13.5 2.2 1.5 9.6 0.2 2.7 2 1 0 2 2 2 0 Ku70/Ku80 C-terminal arm DUF3502 PF12010.8 ETS79814.1 - 0.55 10.9 2.3 8.6 7.0 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3502) DnaJ PF00226.31 ETS79817.1 - 6.2e-06 26.2 0.1 9.6e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 ETS79817.1 - 6.4e-06 26.2 0.1 7.8e-06 25.9 0.1 1.3 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.6 ETS79817.1 - 0.011 15.4 2.9 0.012 15.2 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) DUF4538 PF15061.6 ETS79817.1 - 0.12 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Ribosomal_L24e PF01246.20 ETS79818.1 - 1.5e-30 105.2 4.9 1.5e-30 105.2 4.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e DUF5078 PF16877.5 ETS79818.1 - 0.082 13.4 0.6 0.15 12.6 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5078) DUF3602 PF12223.8 ETS79819.1 - 6.3e-08 33.1 23.5 0.0065 17.0 4.2 4.0 1 1 3 4 4 4 3 Protein of unknown function (DUF3602) zf-C2H2 PF00096.26 ETS79820.1 - 0.046 14.2 5.7 0.12 12.9 5.7 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ETS79820.1 - 0.088 13.3 2.3 2.1 8.9 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 ETS79820.1 - 4.2 8.5 6.0 16 6.6 6.0 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger Chol_subst-bind PF09129.11 ETS79821.1 - 0.04 12.9 0.1 0.06 12.3 0.1 1.2 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding AtuA PF07287.11 ETS79822.1 - 3.6e-128 427.2 0.0 4.4e-128 426.9 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Lactamase_B PF00753.27 ETS79823.1 - 1.2e-07 31.9 0.6 2.6e-07 30.9 0.6 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS79823.1 - 0.0069 15.9 1.5 0.0087 15.6 0.5 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain EthD PF07110.11 ETS79824.1 - 4.8e-19 69.3 0.3 6.4e-19 68.9 0.3 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 ETS79824.1 - 4.4e-07 30.3 0.2 6.3e-07 29.8 0.2 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Oxidored_FMN PF00724.20 ETS79825.1 - 3.5e-73 246.8 0.0 9.1e-51 173.1 0.0 2.0 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.18 ETS79826.1 - 6.4e-18 64.7 0.0 1e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gpi1 PF05024.15 ETS79826.1 - 0.023 14.8 1.0 0.04 14.0 1.0 1.3 1 0 0 1 1 1 0 N-acetylglucosaminyl transferase component (Gpi1) Tannase PF07519.11 ETS79827.1 - 1.6e-102 343.9 1.0 2.6e-102 343.2 1.0 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase Glyco_transf_28 PF03033.20 ETS79828.1 - 2.6e-24 85.9 0.0 4.7e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 ETS79828.1 - 5.7e-06 25.4 0.0 8.8e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 ETS79828.1 - 0.076 12.8 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Fungal_trans_2 PF11951.8 ETS79829.1 - 0.0018 17.2 0.6 0.0027 16.6 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tannase PF07519.11 ETS79830.1 - 3.6e-82 276.7 1.7 4.5e-82 276.4 1.7 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 ETS79830.1 - 5.1e-05 22.6 0.0 0.00084 18.7 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ETS79830.1 - 5.8e-05 22.7 0.0 0.0041 16.6 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ETS79830.1 - 0.0036 17.0 0.5 0.0064 16.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 ETS79830.1 - 0.02 14.5 0.1 0.042 13.5 0.1 1.5 1 0 0 1 1 1 0 Putative esterase RTA1 PF04479.13 ETS79831.1 - 1.1e-52 178.7 9.3 1.3e-52 178.5 9.3 1.0 1 0 0 1 1 1 1 RTA1 like protein RTA1 PF04479.13 ETS79832.1 - 1.1e-59 201.5 8.8 1.1e-59 201.5 8.8 1.9 1 1 1 2 2 2 1 RTA1 like protein DUF4501 PF14946.6 ETS79832.1 - 0.14 12.3 0.0 6.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4501) DUF2070 PF09843.9 ETS79832.1 - 7.1 4.8 6.9 14 3.8 6.9 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Bac_rhamnosid6H PF17389.2 ETS79833.1 - 4.6e-10 39.3 3.4 1.3e-09 37.8 0.5 2.8 3 1 0 3 3 3 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 ETS79833.1 - 7.8e-08 32.0 0.0 3.1e-07 30.1 0.0 2.0 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 ETS79833.1 - 0.00079 18.4 0.0 0.0012 17.8 0.0 1.1 1 0 0 1 1 1 1 Trehalase Glyco_hydro_1 PF00232.18 ETS79834.1 - 5.1e-131 437.2 0.0 6.3e-131 436.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 E2 PF08199.11 ETS79834.1 - 0.68 9.9 5.1 27 4.8 0.3 3.4 2 1 1 3 3 3 0 Bacteriophage E2-like protein Zn_clus PF00172.18 ETS79835.1 - 1.1e-06 28.7 14.8 1.2e-06 28.5 12.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS79835.1 - 0.0049 15.9 0.3 0.0074 15.3 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 ETS79836.1 - 9.2e-84 281.9 28.6 1.1e-83 281.7 28.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS79836.1 - 1.5e-33 116.2 25.5 1.5e-33 116.2 25.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 ETS79836.1 - 3.4e-05 22.3 17.1 4.1e-05 22.1 5.6 3.1 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family LacY_symp PF01306.19 ETS79836.1 - 0.0018 17.2 16.0 0.057 12.2 0.1 2.5 2 0 0 2 2 2 2 LacY proton/sugar symporter Glyco_hydro_2_C PF02836.17 ETS79837.1 - 7.5e-106 353.6 0.1 1e-105 353.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 ETS79837.1 - 2.9e-65 220.3 0.0 4.8e-65 219.6 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 ETS79837.1 - 1.9e-39 135.3 0.0 3.7e-39 134.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 ETS79837.1 - 7.9e-16 58.3 0.0 2.1e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 ETS79837.1 - 1.7e-07 31.8 0.0 4.8e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 ING PF12998.7 ETS79840.1 - 1.3e-05 25.7 0.0 3.1e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 ETS79840.1 - 0.0013 18.5 2.0 0.0013 18.5 2.0 2.4 2 0 0 2 2 2 1 PHD-finger zf-PARP PF00645.18 ETS79840.1 - 0.078 13.8 2.8 0.18 12.7 2.8 1.6 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-LITAF-like PF10601.9 ETS79841.1 - 1.1e-16 60.8 6.3 1.8e-16 60.2 6.3 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain CCDC53 PF10152.9 ETS79841.1 - 0.026 15.0 0.5 0.026 15.0 0.5 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex SARAF PF06682.12 ETS79841.1 - 0.027 14.1 5.3 0.0097 15.6 3.1 1.4 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis zinc_ribbon_2 PF13240.6 ETS79841.1 - 0.072 12.8 2.9 7 6.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Lar_restr_allev PF14354.6 ETS79841.1 - 0.077 13.4 3.0 0.82 10.1 1.2 2.5 1 1 1 2 2 2 0 Restriction alleviation protein Lar Presenilin PF01080.17 ETS79841.1 - 0.23 10.2 0.2 0.26 10.0 0.2 1.2 1 0 0 1 1 1 0 Presenilin DZR PF12773.7 ETS79841.1 - 0.45 10.6 8.7 2 8.5 3.7 2.5 1 1 2 3 3 3 0 Double zinc ribbon Sgf11 PF08209.11 ETS79841.1 - 2.1 7.9 8.9 2 8.0 0.1 2.6 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Pex14_N PF04695.13 ETS79841.1 - 2.7 8.6 28.5 1.3 9.7 1.3 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NOB1_Zn_bind PF08772.11 ETS79841.1 - 7.2 6.8 10.2 24 5.2 0.0 2.8 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Aldo_ket_red PF00248.21 ETS79842.1 - 6.8e-67 225.7 0.0 8.4e-67 225.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_6 PF12697.7 ETS79844.1 - 4.4e-11 43.8 0.0 9.2e-11 42.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS79844.1 - 0.0016 17.7 0.1 0.14 11.4 0.1 2.8 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 ETS79844.1 - 0.002 17.9 0.0 0.0053 16.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 ETS79844.1 - 0.0025 16.8 0.0 0.0074 15.2 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Ser_hydrolase PF06821.13 ETS79844.1 - 0.018 14.9 0.0 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase LIDHydrolase PF10230.9 ETS79844.1 - 0.069 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF900 PF05990.12 ETS79844.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 ETS79844.1 - 0.18 11.5 0.1 0.24 11.1 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein ABC_membrane PF00664.23 ETS79846.1 - 6.3e-88 295.0 27.1 3.7e-45 154.7 12.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ETS79846.1 - 1.7e-62 209.9 0.0 2.9e-30 105.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ETS79846.1 - 6e-15 55.3 3.1 0.00013 21.5 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ETS79846.1 - 1.2e-07 32.3 5.6 0.0033 17.8 0.3 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 ETS79846.1 - 4.4e-07 30.3 0.5 0.023 15.0 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 ETS79846.1 - 2e-06 27.6 0.5 0.0061 16.3 0.1 3.7 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.6 ETS79846.1 - 1.8e-05 24.4 0.0 0.098 12.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 ETS79846.1 - 0.0012 19.4 0.0 0.81 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ETS79846.1 - 0.0013 18.8 0.1 1.1 9.2 0.0 3.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 ETS79846.1 - 0.0013 18.9 2.1 0.36 11.0 0.0 3.2 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ETS79846.1 - 0.0014 18.6 0.0 0.25 11.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 ETS79846.1 - 0.0015 18.9 0.2 9.8 6.6 0.0 3.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 ETS79846.1 - 0.002 18.0 0.5 0.017 14.9 0.0 2.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 ETS79846.1 - 0.0028 17.8 0.0 0.18 11.9 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_25 PF13481.6 ETS79846.1 - 0.0065 16.1 0.1 14 5.2 0.0 3.9 4 0 0 4 4 4 0 AAA domain G-alpha PF00503.20 ETS79846.1 - 0.015 14.4 0.0 0.61 9.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit DUF3987 PF13148.6 ETS79846.1 - 0.02 13.9 0.0 6 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) APS_kinase PF01583.20 ETS79846.1 - 0.025 14.5 0.0 3 7.7 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase ABC_ATPase PF09818.9 ETS79846.1 - 0.026 13.3 0.2 0.14 11.0 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class MMR_HSR1 PF01926.23 ETS79846.1 - 0.026 14.6 0.0 14 5.8 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 ETS79846.1 - 0.031 14.5 0.7 6.4 7.1 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 ETS79846.1 - 0.052 13.1 0.0 7.5 6.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 ETS79846.1 - 0.13 12.7 1.2 3.9 7.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 ETS79846.1 - 0.13 11.9 0.4 0.64 9.7 0.0 2.1 3 0 0 3 3 2 0 AAA ATPase domain PRK PF00485.18 ETS79846.1 - 0.15 11.8 0.1 3.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 ETS79846.1 - 0.18 12.2 0.6 8.8 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 ETS79847.1 - 6.2e-80 267.6 63.8 1.6e-43 148.6 24.5 3.1 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 ETS79847.1 - 9.5e-35 120.1 0.1 2e-16 60.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ETS79847.1 - 1.4e-30 105.1 12.4 8.6e-26 89.7 0.1 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 ETS79847.1 - 4.4e-11 43.2 0.0 9.5e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 ETS79847.1 - 1.8e-06 27.7 0.2 0.00019 21.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS79847.1 - 4.9e-06 27.0 0.6 0.00043 20.7 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 ETS79847.1 - 1.2e-05 24.6 49.5 8.6e-05 21.8 21.0 2.9 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_29 PF13555.6 ETS79847.1 - 8.2e-05 22.3 1.3 0.049 13.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ETS79847.1 - 0.00012 22.1 0.3 0.0048 16.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 ETS79847.1 - 0.00012 22.3 0.6 0.059 13.5 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 ETS79847.1 - 0.0027 17.5 0.6 1.5 8.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 ETS79847.1 - 0.012 16.2 0.1 0.12 12.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ETS79847.1 - 0.014 15.4 0.4 2.3 8.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 ETS79847.1 - 0.021 14.3 0.1 3.4 7.0 0.0 3.2 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 ETS79847.1 - 0.023 14.4 0.7 2.1 8.0 0.6 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ETS79847.1 - 0.033 14.7 0.0 1.1 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ETS79847.1 - 0.039 14.2 2.3 2 8.7 0.3 2.8 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 ETS79847.1 - 0.2 11.6 2.7 3.3 7.6 0.5 2.6 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 ETS79847.1 - 0.53 10.7 2.0 2.1 8.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 ETS79847.1 - 0.82 9.2 4.1 0.98 9.0 0.5 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Peptidase_S28 PF05577.12 ETS79848.1 - 3.3e-47 161.3 1.9 5.6e-46 157.2 1.9 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 MFS_1 PF07690.16 ETS79849.1 - 6.7e-41 140.4 48.4 1.5e-40 139.2 44.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS79849.1 - 1.8e-08 33.7 15.6 1.8e-08 33.7 15.6 2.6 2 2 0 2 2 2 1 Sugar (and other) transporter T5orf172 PF10544.9 ETS79850.1 - 5.3e-25 87.9 0.1 1.4e-24 86.6 0.1 1.7 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 ETS79850.1 - 2.9e-24 85.5 0.1 6.1e-24 84.5 0.1 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 RAI16-like PF10257.9 ETS79852.1 - 2.4e-70 237.2 3.9 3.8e-70 236.6 3.9 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Katanin_con80 PF13925.6 ETS79852.1 - 0.23 11.5 0.9 3.3 7.7 0.2 2.5 2 0 0 2 2 2 0 con80 domain of Katanin Lipase_3 PF01764.25 ETS79853.1 - 5.2e-20 71.7 0.0 1.2e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ETS79853.1 - 0.028 15.0 0.0 0.066 13.8 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 ETS79853.1 - 0.046 13.4 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein RNA_pol_Rpc4 PF05132.14 ETS79853.1 - 0.052 14.0 3.3 0.3 11.5 0.8 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF2974 PF11187.8 ETS79853.1 - 0.068 12.7 0.0 0.53 9.8 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Chlorophyllase2 PF12740.7 ETS79853.1 - 0.083 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme MFMR_assoc PF16596.5 ETS79854.1 - 0.19 12.2 1.5 0.21 12.1 0.1 1.7 2 0 0 2 2 2 0 Disordered region downstream of MFMR Hydrophobin PF01185.18 ETS79855.1 - 1.6e-09 38.2 5.3 2.1e-09 37.8 5.3 1.2 1 0 0 1 1 1 1 Fungal hydrophobin SNF2_N PF00176.23 ETS79857.1 - 2.6e-64 217.1 2.0 6e-64 216.0 0.7 2.1 1 1 1 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 ETS79857.1 - 4.5e-48 163.0 17.3 4.5e-48 163.0 17.3 5.8 4 2 0 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 ETS79857.1 - 1.8e-20 73.3 0.0 4.9e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS79857.1 - 1.7e-07 31.4 0.0 1.7e-07 31.4 0.0 3.2 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 ETS79857.1 - 0.015 14.5 2.6 0.049 12.8 0.0 3.1 3 1 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 Fe_hyd_lg_C PF02906.14 ETS79857.1 - 0.92 9.1 7.5 0.45 10.1 3.6 2.4 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain ABC_tran PF00005.27 ETS79858.1 - 1.8e-45 154.8 0.0 4e-21 76.0 0.0 3.2 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 ETS79858.1 - 2.4e-18 66.0 8.0 2.4e-18 66.0 8.0 2.9 4 0 0 4 4 1 1 ABC transporter AAA_21 PF13304.6 ETS79858.1 - 2.8e-18 66.8 0.1 0.00027 20.8 0.0 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETS79858.1 - 7.1e-10 38.7 0.1 0.15 11.4 0.0 4.5 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ETS79858.1 - 1.4e-08 35.5 8.1 0.018 15.6 0.1 3.9 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 ETS79858.1 - 3.4e-08 33.1 0.0 0.012 15.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 ETS79858.1 - 4e-07 30.1 0.3 0.012 15.3 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 ETS79858.1 - 8e-07 29.1 0.6 0.005 16.8 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 ETS79858.1 - 9.7e-07 29.3 0.0 0.014 15.8 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 ETS79858.1 - 2.9e-06 27.9 0.4 0.068 13.7 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.6 ETS79858.1 - 4e-06 27.2 0.0 0.0021 18.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ETS79858.1 - 8.2e-06 26.1 0.0 0.079 13.2 0.1 2.9 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 ETS79858.1 - 1.5e-05 25.0 0.0 0.064 13.3 0.0 3.3 3 0 0 3 3 2 2 50S ribosome-binding GTPase NACHT PF05729.12 ETS79858.1 - 2.8e-05 24.1 0.1 0.2 11.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 ETS79858.1 - 2.8e-05 24.5 0.0 0.56 10.6 0.0 3.4 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ETS79858.1 - 5.4e-05 23.2 0.0 0.25 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ETS79858.1 - 0.00012 22.4 0.2 1.6 9.2 0.0 3.4 4 0 0 4 4 3 2 RNA helicase AAA_14 PF13173.6 ETS79858.1 - 0.00052 20.1 0.0 1.8 8.6 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ETS79858.1 - 0.00098 19.3 0.0 1 9.5 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ETS79858.1 - 0.0017 18.1 0.2 1.4 8.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_27 PF13514.6 ETS79858.1 - 0.0024 17.5 0.0 0.94 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 ETS79858.1 - 0.003 17.8 0.0 2.8 8.2 0.0 3.1 2 1 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 ETS79858.1 - 0.0059 15.8 0.7 5.2 6.2 0.0 3.6 4 0 0 4 4 4 0 NB-ARC domain AAA_17 PF13207.6 ETS79858.1 - 0.0074 16.7 0.1 2.7 8.4 0.0 3.3 3 0 0 3 3 2 1 AAA domain ATPase_2 PF01637.18 ETS79858.1 - 0.0099 15.8 0.3 3.5 7.5 0.0 3.1 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea DUF2813 PF11398.8 ETS79858.1 - 0.01 15.1 0.0 1.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) AAA_30 PF13604.6 ETS79858.1 - 0.021 14.5 0.0 2.7 7.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ETS79858.1 - 0.025 14.1 0.0 2.1 7.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 ETS79858.1 - 0.031 14.3 0.3 28 4.7 0.0 3.9 3 1 1 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Phage_tail_2 PF06199.11 ETS79858.1 - 0.036 14.2 0.4 0.35 11.0 0.0 2.7 3 0 0 3 3 3 0 Phage tail tube protein AAA_25 PF13481.6 ETS79858.1 - 0.043 13.4 0.1 3.8 7.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain DAP3 PF10236.9 ETS79858.1 - 0.057 12.6 0.4 4.1 6.5 0.1 2.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 IstB_IS21 PF01695.17 ETS79858.1 - 0.058 13.1 0.0 10 5.8 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF815 PF05673.13 ETS79858.1 - 0.058 12.5 0.2 2.6 7.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 ETS79858.1 - 0.062 13.2 0.8 5.1 7.0 0.0 3.0 3 0 0 3 3 2 0 NTPase Rad17 PF03215.15 ETS79858.1 - 0.082 12.8 0.1 14 5.6 0.0 3.0 3 0 0 3 3 3 0 Rad17 P-loop domain DUF2156 PF09924.9 ETS79858.1 - 0.088 11.8 0.2 0.5 9.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2156) Dynamin_N PF00350.23 ETS79858.1 - 0.11 12.6 0.2 32 4.5 0.0 3.5 3 1 1 4 4 4 0 Dynamin family ATP-synt_ab PF00006.25 ETS79858.1 - 0.11 12.1 0.0 1.4 8.6 0.0 2.5 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MCM PF00493.23 ETS79858.1 - 0.16 11.1 1.2 13 4.8 0.0 2.9 3 0 0 3 3 3 0 MCM P-loop domain PduV-EutP PF10662.9 ETS79858.1 - 0.18 11.6 0.7 13 5.5 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF5337 PF17272.2 ETS79859.1 - 0.48 10.3 2.5 1 9.2 2.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5337) DUF805 PF05656.14 ETS79859.1 - 1.1 9.7 4.7 1.6 9.2 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Lipase_GDSL_2 PF13472.6 ETS79860.1 - 1.2e-11 45.3 0.0 1.5e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS79860.1 - 7.1e-10 39.2 0.0 8.5e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 ETS79860.1 - 0.0024 18.0 0.0 0.0039 17.3 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Peptidase_M16_C PF05193.21 ETS79861.1 - 1e-20 74.6 0.0 2.7e-17 63.4 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ETS79861.1 - 2.7e-08 33.9 0.2 4.2e-06 26.8 0.0 2.8 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 ETS79861.1 - 0.24 10.5 4.5 6.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Peptidase M16C associated Zw10 PF06248.13 ETS79862.1 - 2.3e-06 26.5 3.3 0.0012 17.5 2.8 2.4 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 ETS79862.1 - 1.7e-05 24.6 0.0 3.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Com_YlbF PF06133.11 ETS79862.1 - 0.14 12.8 0.7 0.53 10.9 0.7 2.0 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA ArsR PF09824.9 ETS79862.1 - 0.17 11.5 1.0 5.1 6.7 0.1 3.1 3 0 0 3 3 3 0 ArsR transcriptional regulator Trns_repr_metal PF02583.17 ETS79862.1 - 0.63 10.4 3.4 0.73 10.2 0.6 2.6 2 1 0 2 2 2 0 Metal-sensitive transcriptional repressor PET10 PF17316.2 ETS79863.1 - 0.15 11.6 1.1 0.29 10.6 1.1 1.4 1 0 0 1 1 1 0 Petite colonies protein 10 TssN PF17555.2 ETS79864.1 - 0.13 11.6 0.1 0.15 11.4 0.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN MPS-4 PF17523.2 ETS79864.1 - 0.19 11.9 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 MARVEL PF01284.23 ETS79866.1 - 5.5e-05 23.2 7.5 0.00022 21.3 7.5 1.9 1 1 0 1 1 1 1 Membrane-associating domain AAA PF00004.29 ETS79870.1 - 1.2e-52 177.8 0.0 4.2e-42 143.7 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 ETS79870.1 - 2.1e-07 30.9 0.0 5.9e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 ETS79870.1 - 3.1e-07 30.9 0.3 0.0013 19.1 0.3 3.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_lid_3 PF17862.1 ETS79870.1 - 4.3e-07 29.6 0.1 1.7e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 ETS79870.1 - 6e-06 26.5 0.0 1.8e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 ETS79870.1 - 2e-05 24.9 0.3 0.051 13.8 0.2 3.8 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.6 ETS79870.1 - 2.4e-05 24.5 0.0 0.024 14.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ETS79870.1 - 0.00029 20.8 0.0 0.0098 15.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ETS79870.1 - 0.0024 17.6 0.0 0.054 13.2 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 ETS79870.1 - 0.007 16.7 0.0 0.042 14.2 0.0 2.2 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 ETS79870.1 - 0.0086 15.3 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 ETS79870.1 - 0.0093 15.4 0.2 0.15 11.4 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 ETS79870.1 - 0.015 15.9 0.0 0.064 13.8 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 ETS79870.1 - 0.019 15.0 0.0 0.084 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ETS79870.1 - 0.033 13.7 0.0 0.093 12.2 0.0 1.7 2 0 0 2 2 1 0 P-loop containing dynein motor region NACHT PF05729.12 ETS79870.1 - 0.064 13.2 0.1 1.2 9.0 0.0 3.0 3 0 0 3 3 3 0 NACHT domain ABC_tran PF00005.27 ETS79870.1 - 0.081 13.4 0.0 0.38 11.3 0.0 2.2 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 ETS79870.1 - 0.082 13.1 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 ETS79870.1 - 0.089 11.9 0.0 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 ETS79870.1 - 0.099 12.5 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 ETS79870.1 - 0.15 12.2 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Bromodomain adh_short_C2 PF13561.6 ETS79871.1 - 3e-69 233.2 1.9 3.3e-69 233.0 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS79871.1 - 3.1e-55 186.7 0.8 4.3e-55 186.2 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS79871.1 - 8.3e-12 45.4 0.1 1.1e-11 45.0 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS79871.1 - 1.8e-05 24.0 0.1 2.3e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 ETS79871.1 - 2.2e-05 24.6 0.1 3.9e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.21 ETS79871.1 - 0.00025 20.6 0.3 0.00036 20.1 0.3 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4347 PF14252.6 ETS79871.1 - 0.017 15.0 1.2 0.021 14.7 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) ADH_zinc_N PF00107.26 ETS79871.1 - 0.057 13.4 0.3 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 ETS79871.1 - 0.08 13.6 0.2 0.19 12.5 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase domain Bac_luciferase PF00296.20 ETS79872.1 - 2.2e-56 191.6 2.4 2.9e-56 191.2 2.4 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase HTH_38 PF13936.6 ETS79872.1 - 0.16 11.8 0.1 0.44 10.4 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Aa_trans PF01490.18 ETS79873.1 - 1.4e-24 86.6 25.0 1.6e-24 86.4 25.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AAA PF00004.29 ETS79874.1 - 8.4e-14 52.1 0.0 2.6e-13 50.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS79874.1 - 0.048 13.9 0.3 0.33 11.2 0.3 2.3 1 1 0 1 1 1 0 AAA domain CorA PF01544.18 ETS79875.1 - 6.3e-05 22.4 7.4 0.00017 21.0 7.4 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein EMP70 PF02990.16 ETS79875.1 - 0.018 13.7 0.8 0.024 13.3 0.8 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Sld5 PF05916.11 ETS79875.1 - 0.18 12.2 0.7 0.28 11.6 0.7 1.4 1 0 0 1 1 1 0 GINS complex protein PNP_UDP_1 PF01048.20 ETS79876.1 - 8.2e-13 48.2 0.1 6.1e-12 45.3 0.1 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily MRP-L28 PF09812.9 ETS79877.1 - 3 8.0 6.0 0.41 10.8 1.7 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 CENP_C_N PF15622.6 ETS79879.1 - 0.061 12.8 0.2 0.1 12.0 0.2 1.2 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal ALC PF17527.2 ETS79879.1 - 0.11 12.1 0.7 0.23 11.1 0.7 1.4 1 0 0 1 1 1 0 Phage ALC protein Dynamin_N PF00350.23 ETS79880.1 - 4.9e-43 147.1 0.0 1e-42 146.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 ETS79880.1 - 5e-13 48.9 0.1 1.1e-11 44.5 0.1 2.3 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 ETS79880.1 - 8.3e-06 25.9 0.2 0.00031 20.8 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 ETS79880.1 - 0.099 12.4 0.0 8 6.2 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Papilin_u7 PF16626.5 ETS79880.1 - 0.28 11.8 4.4 0.99 10.0 1.7 2.4 2 0 0 2 2 2 0 Linking region between Kunitz_BPTI and I-set on papilin AAA_16 PF13191.6 ETS79880.1 - 0.42 11.0 0.0 0.42 11.0 0.0 3.1 4 1 0 4 4 4 0 AAA ATPase domain Roc PF08477.13 ETS79880.1 - 0.62 10.3 2.3 0.77 10.0 0.0 2.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 ETS79882.1 - 1.2e-35 121.7 3.2 8.4e-35 119.0 0.9 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 ETS79882.1 - 3.3e-21 75.5 0.0 6.4e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 ETS79882.1 - 2.7e-19 69.0 0.3 5e-19 68.1 0.3 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 ETS79882.1 - 5.3e-13 48.8 0.0 8.5e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ETS79882.1 - 5.8e-05 23.2 0.2 0.036 14.1 0.0 2.4 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 ETS79882.1 - 0.071 12.1 0.2 0.16 10.9 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 ETS79882.1 - 0.096 11.8 0.0 0.25 10.4 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain Spo12 PF05032.12 ETS79883.1 - 2.3e-16 59.4 0.2 4.2e-16 58.6 0.2 1.4 1 0 0 1 1 1 1 Spo12 family DUF3226 PF11536.8 ETS79883.1 - 0.034 13.8 0.1 0.04 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) Acyl-CoA_dh_1 PF00441.24 ETS79884.1 - 3.6e-28 98.7 0.1 5.7e-28 98.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ETS79884.1 - 6.8e-20 71.1 0.0 1.2e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ETS79884.1 - 2.5e-15 57.1 0.0 6.3e-15 55.8 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ETS79884.1 - 4.9e-13 49.5 0.1 9.5e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Torus PF16131.5 ETS79885.1 - 4.5e-42 143.2 0.2 1.6e-41 141.4 0.3 1.9 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 ETS79885.1 - 9.1e-08 31.8 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ETS79885.1 - 0.00089 19.2 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 ETS79885.1 - 0.0032 17.5 0.5 0.0032 17.5 0.5 1.9 2 0 0 2 2 2 1 Zinc finger domain UreF PF01730.16 ETS79886.1 - 8.9e-21 74.9 1.0 8.9e-21 74.9 1.0 1.5 2 0 0 2 2 2 1 UreF Sugarporin_N PF11471.8 ETS79886.1 - 0.013 15.5 1.3 0.037 14.0 1.3 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Lzipper-MIP1 PF14389.6 ETS79886.1 - 0.049 13.9 0.1 0.089 13.1 0.1 1.4 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Cut12 PF11500.8 ETS79887.1 - 8.9e-41 139.2 17.6 8.9e-41 139.2 17.6 4.7 3 2 0 3 3 3 1 Spindle pole body formation-associated protein DUF5476 PF17570.2 ETS79887.1 - 0.014 15.8 1.4 0.062 13.7 0.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5476) SseC PF04888.12 ETS79887.1 - 0.11 12.0 3.1 0.31 10.6 3.1 1.8 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family Bacillus_HBL PF05791.11 ETS79887.1 - 0.16 11.8 14.1 0.049 13.5 8.2 2.4 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) WD40_alt PF14077.6 ETS79887.1 - 8.9 6.3 10.3 9 6.2 0.6 3.3 2 1 1 3 3 3 0 Alternative WD40 repeat motif HGTP_anticodon2 PF12745.7 ETS79888.1 - 5.1e-80 268.8 0.3 5.1e-80 268.8 0.3 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 ETS79888.1 - 1.1e-66 225.0 0.0 3.8e-29 101.9 0.0 4.6 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 ETS79888.1 - 1.5e-37 129.3 0.0 1.9e-13 50.3 0.0 3.7 3 1 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 ETS79888.1 - 2.6e-12 46.7 0.6 4.2e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.22 ETS79888.1 - 3.7e-12 46.5 0.1 1.4e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 RWD domain APH PF01636.23 ETS79888.1 - 1.6e-05 24.9 2.9 0.16 11.9 0.0 3.4 3 0 0 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ETS79888.1 - 0.014 14.2 5.0 0.64 8.7 0.0 3.0 3 1 0 3 3 3 0 Fungal protein kinase RIO1 PF01163.22 ETS79888.1 - 0.097 12.3 0.1 0.62 9.6 0.0 2.3 2 0 0 2 2 2 0 RIO1 family DUF1996 PF09362.10 ETS79889.1 - 1.1e-71 241.6 1.4 1.7e-71 240.9 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 ETS79889.1 - 4.6e-52 174.1 56.9 1.1e-20 73.5 11.9 3.7 3 0 0 3 3 3 3 WSC domain Sugar_tr PF00083.24 ETS79890.1 - 3.8e-99 332.6 21.4 4.4e-99 332.4 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS79890.1 - 1.2e-14 54.0 34.6 1.2e-11 44.1 14.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2842 PF11003.8 ETS79890.1 - 2.3 8.5 8.9 0.84 9.9 1.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2842) Ank_2 PF12796.7 ETS79891.1 - 1.5e-40 137.6 1.5 6.4e-14 52.3 0.0 4.9 4 1 1 5 5 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS79891.1 - 2.1e-28 98.3 2.9 1.2e-09 38.5 0.1 5.4 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS79891.1 - 7.1e-25 84.4 6.6 0.013 16.0 0.1 8.7 9 0 0 9 9 7 6 Ankyrin repeat Ank_5 PF13857.6 ETS79891.1 - 1.4e-20 73.1 4.2 6.8e-05 23.1 0.1 6.8 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 ETS79891.1 - 1.6e-18 66.2 12.3 0.026 14.9 0.0 8.0 8 0 0 8 8 7 5 Ankyrin repeat NACHT PF05729.12 ETS79891.1 - 9e-05 22.5 0.5 0.023 14.6 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 ETS79891.1 - 0.00012 22.5 1.6 0.0042 17.5 1.0 3.2 2 1 0 2 2 2 1 AAA ATPase domain PGAP1 PF07819.13 ETS79891.1 - 0.00058 19.7 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 ETS79891.1 - 0.0023 17.5 0.1 0.021 14.3 0.1 2.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 ETS79891.1 - 0.0054 16.0 0.0 0.018 14.3 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AAA_22 PF13401.6 ETS79891.1 - 0.0084 16.4 0.0 0.068 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 ETS79891.1 - 0.025 14.0 0.0 0.085 12.2 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 ETS79891.1 - 0.044 13.0 0.0 0.099 11.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 ETS79891.1 - 0.044 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ETS79891.1 - 0.05 13.6 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 ETS79891.1 - 0.059 13.4 0.0 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 ETS79891.1 - 0.06 13.1 0.2 0.15 11.8 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 ETS79891.1 - 0.078 13.4 0.0 0.49 10.8 0.0 2.3 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 ETS79891.1 - 0.08 13.5 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 ETS79891.1 - 0.086 13.4 0.0 0.3 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 ETS79891.1 - 0.14 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 ETS79891.1 - 0.17 12.3 0.0 0.92 9.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 ETS79891.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PUL PF08324.11 ETS79893.1 - 5.9e-64 216.0 0.0 9.9e-64 215.2 0.0 1.4 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 ETS79893.1 - 4.8e-35 120.6 0.0 8.3e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 ETS79893.1 - 2.1e-15 56.6 0.0 4.2e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 ETS79893.1 - 1.7e-06 28.0 0.0 3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 ETS79893.1 - 5.7e-05 23.5 0.4 0.00078 19.9 0.4 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 ETS79893.1 - 0.0005 20.1 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.21 ETS79893.1 - 0.025 14.5 0.1 0.081 12.8 0.0 1.8 1 1 1 2 2 2 0 AhpC/TSA family OST3_OST6 PF04756.13 ETS79893.1 - 0.065 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Redoxin PF08534.10 ETS79893.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Redoxin GDA1_CD39 PF01150.17 ETS79894.1 - 1.7e-100 336.7 0.0 2.3e-100 336.3 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family AAA_lid_2 PF17863.1 ETS79895.1 - 9.6e-05 22.1 0.2 0.00023 20.9 0.2 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 ETS79895.1 - 0.007 16.2 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Metal_resist PF13801.6 ETS79896.1 - 0.19 11.9 3.2 0.22 11.7 0.2 2.2 2 0 0 2 2 2 0 Heavy-metal resistance Spb1_C PF07780.12 ETS79897.1 - 3.9e-85 284.8 26.6 3.9e-85 284.8 26.6 3.6 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 ETS79897.1 - 3.3e-55 186.9 0.0 5.9e-55 186.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 ETS79897.1 - 2.6e-53 180.2 12.6 2.6e-53 180.2 12.6 5.2 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 ETS79897.1 - 0.013 15.3 0.0 0.043 13.6 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain DUF4519 PF15012.6 ETS79897.1 - 1.2 9.4 7.6 7.8 6.8 7.6 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) WD40 PF00400.32 ETS79898.1 - 1e-13 51.5 7.6 0.016 16.0 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS79898.1 - 9.5e-10 38.6 0.0 0.016 15.5 0.0 5.1 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 ETS79898.1 - 0.22 10.5 0.0 0.39 9.7 0.0 1.3 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Met_asp_mut_E PF06368.11 ETS79898.1 - 0.26 9.7 0.0 0.4 9.1 0.0 1.1 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Ge1_WD40 PF16529.5 ETS79898.1 - 0.31 9.9 0.2 8.6 5.2 0.0 2.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Heme_oxygenase PF01126.20 ETS79899.1 - 1.8e-12 47.5 0.0 4.5e-12 46.2 0.0 1.6 2 0 0 2 2 2 1 Heme oxygenase Integrase_1 PF12835.7 ETS79899.1 - 0.0044 17.1 0.5 0.0091 16.1 0.5 1.5 1 0 0 1 1 1 1 Integrase TRI12 PF06609.13 ETS79900.1 - 4.9e-54 183.8 25.6 6.5e-54 183.4 25.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ETS79900.1 - 9.1e-24 84.0 60.2 6.9e-22 77.9 56.8 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS79900.1 - 8e-12 44.8 11.2 8e-12 44.8 11.2 3.6 3 1 1 4 4 4 1 Sugar (and other) transporter Ebp2 PF05890.12 ETS79901.1 - 1.1e-95 320.3 18.3 1.1e-95 320.3 18.3 1.9 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Dppa2_A PF14049.6 ETS79901.1 - 0.84 9.8 0.0 0.84 9.8 0.0 3.4 3 0 0 3 3 3 0 Dppa2/4 conserved region in higher vertebrates Ras PF00071.22 ETS79902.1 - 3.7e-55 185.9 0.0 4.5e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS79902.1 - 8.5e-32 109.9 0.0 1.2e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS79902.1 - 7.5e-13 48.3 0.0 8.1e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ETS79902.1 - 2.7e-08 33.9 0.0 4.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ETS79902.1 - 5.2e-07 29.3 0.0 6.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ETS79902.1 - 2.6e-05 23.9 0.0 0.0011 18.6 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ETS79902.1 - 0.00034 20.6 0.1 0.0038 17.2 0.1 2.2 1 1 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 ETS79902.1 - 0.0023 17.4 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 ETS79902.1 - 0.0034 17.4 0.0 0.0055 16.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 ETS79902.1 - 0.0052 16.6 0.1 0.16 11.8 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 ETS79902.1 - 0.011 16.0 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ETS79902.1 - 0.016 15.6 0.1 0.021 15.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 ETS79902.1 - 0.021 14.1 0.1 0.049 12.9 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 ETS79902.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 ETS79902.1 - 0.026 14.2 0.1 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 ETS79902.1 - 0.027 14.0 0.1 0.043 13.3 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 ETS79902.1 - 0.06 12.9 0.0 0.15 11.7 0.0 1.6 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 ETS79902.1 - 0.072 13.5 0.1 0.33 11.3 0.1 2.1 1 1 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 ETS79902.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 ETS79902.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 ETS79902.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 ETS79902.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein EamA PF00892.20 ETS79903.1 - 3e-12 46.9 31.2 6.5e-07 29.6 2.9 3.1 3 0 0 3 3 3 3 EamA-like transporter family DUF3955 PF13127.6 ETS79903.1 - 8.1e-10 38.4 0.3 8.1e-10 38.4 0.3 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) PUNUT PF16913.5 ETS79903.1 - 1.3e-08 34.4 2.6 6.1e-08 32.3 0.1 2.3 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 ETS79903.1 - 2.6e-06 27.1 1.9 2.6e-06 27.1 1.9 1.9 3 0 0 3 3 3 1 Solute carrier family 35 Cyanate_lyase PF02560.14 ETS79904.1 - 3.1e-31 107.0 0.0 4.6e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 ETS79904.1 - 0.0056 17.0 0.0 0.0093 16.3 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ETS79904.1 - 0.084 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix Sigma70_r4_2 PF08281.12 ETS79904.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 DUF2613 PF11021.8 ETS79905.1 - 0.62 10.2 0.1 0.62 10.2 0.1 4.5 4 1 2 6 6 6 0 Protein of unknown function (DUF2613) DUF1754 PF08555.10 ETS79906.1 - 3.1e-10 40.7 15.4 5.1e-10 40.0 15.4 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) CDC27 PF09507.10 ETS79906.1 - 0.13 11.7 14.7 0.14 11.5 14.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PBP PF01161.20 ETS79908.1 - 1.9e-07 31.5 0.0 3.3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L4 PF00573.22 ETS79909.1 - 3.3e-48 163.9 0.0 4.6e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Rep_fac-A_3 PF08661.11 ETS79910.1 - 2.1e-20 73.0 0.3 2.3e-20 72.9 0.3 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF4412 PF14371.6 ETS79910.1 - 0.094 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4412) bZIP_1 PF00170.21 ETS79911.1 - 1.4e-08 34.7 6.0 2.4e-08 33.9 6.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ETS79911.1 - 7.3e-08 32.4 4.4 1.4e-07 31.5 4.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ETS79911.1 - 0.0043 17.6 2.0 0.0091 16.5 2.0 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor cobW PF02492.19 ETS79913.1 - 1.2e-40 138.9 0.0 1.6e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 ETS79913.1 - 0.00043 20.2 0.1 0.0013 18.6 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 ETS79913.1 - 0.0072 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 ETS79913.1 - 0.029 14.6 0.0 0.067 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ETS79913.1 - 0.034 13.9 0.1 0.33 10.7 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ETS79913.1 - 0.035 14.0 0.0 9.6 6.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase TrwB_AAD_bind PF10412.9 ETS79913.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 ETS79913.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.6 ETS79913.1 - 0.15 12.4 0.1 0.41 11.0 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain DUF2075 PF09848.9 ETS79913.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF463 PF04317.12 ETS79913.1 - 0.2 10.6 0.1 0.34 9.8 0.1 1.3 1 0 0 1 1 1 0 YcjX-like family, DUF463 GFO_IDH_MocA PF01408.22 ETS79916.1 - 2.7e-29 102.4 0.9 4.2e-29 101.8 0.9 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ETS79916.1 - 4.6e-12 46.0 0.0 9.2e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding PF02629.19 ETS79916.1 - 2.4e-08 34.6 1.3 4.3e-08 33.7 1.3 1.4 1 0 0 1 1 1 1 CoA binding domain CoA_binding_2 PF13380.6 ETS79916.1 - 2.8e-05 24.6 0.5 5.4e-05 23.7 0.5 1.5 1 0 0 1 1 1 1 CoA binding domain Shikimate_DH PF01488.20 ETS79916.1 - 0.008 16.2 0.1 0.012 15.7 0.1 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 ETS79916.1 - 0.012 16.0 0.2 0.027 14.9 0.2 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ETS79916.1 - 0.034 14.0 0.1 0.056 13.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ETS79916.1 - 0.042 13.2 0.1 0.066 12.6 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ETS79916.1 - 0.089 13.4 0.7 0.19 12.3 0.7 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent p450 PF00067.22 ETS79917.1 - 6e-41 140.6 0.1 8.7e-41 140.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_39 PF01229.17 ETS79918.1 - 0.00028 19.6 0.2 0.00037 19.2 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 MFS_1 PF07690.16 ETS79919.1 - 4.7e-27 94.8 29.4 1.8e-26 92.9 29.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4387 PF14330.6 ETS79920.1 - 3.4e-40 136.7 0.0 1.7e-39 134.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4387) AtuA PF07287.11 ETS79920.1 - 3.6e-18 65.4 0.0 8e-17 61.0 0.0 2.0 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Egh16-like PF11327.8 ETS79922.1 - 1.1e-41 143.2 6.7 1.4e-41 142.9 6.7 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor Ank_2 PF12796.7 ETS79923.1 - 2.4e-72 239.6 16.2 3.3e-14 53.2 0.0 14.4 7 6 9 16 16 16 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS79923.1 - 2.5e-63 209.7 30.2 8.7e-09 35.8 0.0 23.7 17 6 10 27 27 27 13 Ankyrin repeats (many copies) Ank PF00023.30 ETS79923.1 - 7.6e-51 168.4 39.6 1.1e-06 28.7 0.7 21.3 23 3 0 23 23 23 9 Ankyrin repeat Ank_5 PF13857.6 ETS79923.1 - 2.4e-45 152.0 46.2 4.5e-07 30.0 0.0 20.5 20 4 3 23 23 23 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS79923.1 - 5.9e-42 136.8 18.1 0.00013 22.1 0.0 21.4 24 2 0 24 24 24 7 Ankyrin repeat NACHT PF05729.12 ETS79923.1 - 1.6e-09 37.9 0.0 4.2e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS79923.1 - 6.3e-07 29.9 0.2 5.4e-06 26.9 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS79923.1 - 0.00049 20.4 0.0 0.0058 16.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain HET PF06985.11 ETS79924.1 - 5.7e-30 104.6 2.9 1.3e-29 103.4 2.9 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PBP1_TM PF14812.6 ETS79924.1 - 7.3 7.0 8.0 17 5.9 8.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NACHT PF05729.12 ETS79925.1 - 3.9e-10 39.9 0.1 1.1e-09 38.4 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS79925.1 - 7.8e-07 29.6 0.1 2.4e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS79925.1 - 0.00037 20.8 0.0 0.0013 19.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ETS79925.1 - 0.00087 19.7 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ETS79925.1 - 0.023 14.2 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 ETS79925.1 - 0.046 13.4 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 ETS79925.1 - 0.089 11.8 0.1 0.26 10.3 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.9 ETS79925.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.20 ETS79925.1 - 0.14 12.1 0.0 0.41 10.5 0.0 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase IstB_IS21 PF01695.17 ETS79925.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Myosin_head PF00063.21 ETS79925.1 - 0.21 9.8 0.0 0.32 9.2 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) AAA PF00004.29 ETS79926.1 - 9.3e-16 58.5 0.0 1.7e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS79926.1 - 0.00035 21.0 0.0 0.00096 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS79926.1 - 0.006 16.9 0.2 0.16 12.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain Zot PF05707.12 ETS79926.1 - 0.087 12.5 0.0 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_30 PF13604.6 ETS79926.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 ETS79926.1 - 0.16 12.1 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Torsin Ntox1 PF15500.6 ETS79927.1 - 0.1 13.0 0.1 0.38 11.1 0.1 2.0 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 Arginase PF00491.21 ETS79928.1 - 3.1e-24 86.0 0.0 3.7e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family Tannase PF07519.11 ETS79929.1 - 4.9e-92 309.3 0.7 5.6e-92 309.1 0.7 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 ETS79929.1 - 1.3e-06 28.0 0.3 0.029 13.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ETS79929.1 - 0.005 16.1 0.0 0.19 11.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DegT_DnrJ_EryC1 PF01041.17 ETS79930.1 - 0.071 12.4 1.0 0.1 11.8 1.0 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family TPR_12 PF13424.6 ETS79931.1 - 2.9e-54 181.3 15.3 5.6e-14 52.2 0.1 5.4 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 ETS79931.1 - 7.7e-43 143.2 6.9 3.3e-09 36.3 0.0 7.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 ETS79931.1 - 1.3e-15 56.4 9.0 9.5e-06 25.2 0.5 7.5 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 ETS79931.1 - 9.5e-15 53.5 9.3 0.0013 18.6 0.3 7.1 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 ETS79931.1 - 3.2e-13 48.7 7.5 8.2e-06 25.5 0.0 7.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 ETS79931.1 - 4.6e-13 48.3 7.6 0.0062 16.7 0.8 7.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS79931.1 - 1.6e-12 47.5 2.0 7.1e-06 25.6 0.0 2.5 1 1 0 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 ETS79931.1 - 7.2e-12 45.1 9.1 0.36 11.8 0.2 7.8 6 2 2 8 8 7 3 Tetratricopeptide repeat NB-ARC PF00931.22 ETS79931.1 - 8.1e-11 41.6 0.0 1.5e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain HET PF06985.11 ETS79931.1 - 7.3e-10 39.4 6.9 2.2e-08 34.6 0.7 2.9 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_16 PF13432.6 ETS79931.1 - 7.5e-10 39.3 0.0 0.012 16.2 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 ETS79931.1 - 1.3e-08 34.7 1.9 0.014 15.9 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 ETS79931.1 - 2.4e-06 27.9 6.2 0.17 12.4 0.0 5.4 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 ETS79931.1 - 3.7e-06 26.8 2.1 0.00049 20.0 0.4 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS79931.1 - 3.9e-05 23.8 2.9 0.17 12.1 0.2 4.5 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 AAA_16 PF13191.6 ETS79931.1 - 0.00011 22.6 0.1 0.00075 19.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Coatomer_E PF04733.14 ETS79931.1 - 0.00021 20.8 1.0 0.066 12.6 0.2 2.6 2 0 0 2 2 2 2 Coatomer epsilon subunit MIT PF04212.18 ETS79931.1 - 0.0014 18.7 0.3 0.053 13.6 0.0 3.5 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 ETS79931.1 - 0.0018 18.5 5.5 5.6 7.6 0.1 5.5 7 0 0 7 7 5 1 Tetratricopeptide repeat PPR PF01535.20 ETS79931.1 - 0.0074 16.5 6.9 5.9 7.4 0.1 5.6 5 0 0 5 5 5 1 PPR repeat AAA_22 PF13401.6 ETS79931.1 - 0.0094 16.2 0.0 0.06 13.6 0.0 2.4 2 0 0 2 2 1 1 AAA domain TPR_5 PF12688.7 ETS79931.1 - 0.015 15.5 0.6 13 6.1 0.1 3.3 3 0 0 3 3 3 0 Tetratrico peptide repeat TPR_11 PF13414.6 ETS79931.1 - 0.033 13.9 6.1 0.08 12.6 0.5 3.6 4 0 0 4 4 4 0 TPR repeat SPO22 PF08631.10 ETS79931.1 - 0.034 13.6 6.0 12 5.3 0.3 3.6 2 2 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like SNAP PF14938.6 ETS79931.1 - 0.05 13.0 1.0 1.1 8.6 0.0 2.2 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP DUF2989 PF11207.8 ETS79931.1 - 2.6 7.7 5.6 1.1 9.0 0.6 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2989) Pepsin-I3 PF06394.13 ETS79932.1 - 0.18 12.1 0.0 8.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Pkinase PF00069.25 ETS79934.1 - 1.1e-51 175.8 0.0 2.8e-51 174.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS79934.1 - 2.7e-20 72.7 0.0 1.2e-19 70.7 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 ETS79934.1 - 0.008 15.8 0.2 0.11 12.0 0.0 2.5 2 0 0 2 2 2 1 RIO1 family Mtc PF03820.17 ETS79935.1 - 8.1e-119 396.3 0.0 9.1e-119 396.1 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Beta-lactamase PF00144.24 ETS79936.1 - 1.4e-36 126.4 0.0 1.8e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 ETS79936.1 - 0.01 15.3 0.1 0.018 14.5 0.1 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase p450 PF00067.22 ETS79937.1 - 2.9e-34 118.6 0.1 6.4e-24 84.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF3435 PF11917.8 ETS79940.1 - 0.00015 20.8 0.1 0.0013 17.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) Pkinase PF00069.25 ETS79942.1 - 1.1e-50 172.4 0.0 1.8e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS79942.1 - 3.6e-27 95.3 0.0 5.1e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 ETS79942.1 - 0.019 14.6 0.1 0.14 11.8 0.0 2.2 3 0 0 3 3 3 0 RIO1 family Kinase-like PF14531.6 ETS79942.1 - 0.023 14.0 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 ETS79942.1 - 0.032 13.6 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_L_2 PF13656.6 ETS79944.1 - 2.7e-30 104.0 0.0 4e-30 103.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 ETS79944.1 - 1.3e-11 43.7 0.0 1.3e-10 40.5 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.6 ETS79945.1 - 9.8e-08 32.6 0.1 1.3e-07 32.2 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 ETS79945.1 - 8.6e-06 25.7 0.3 1.9e-05 24.6 0.1 1.7 2 1 0 2 2 2 1 Complex 1 protein (LYR family) G10 PF01125.17 ETS79946.1 - 2.1e-63 212.5 6.8 2.3e-63 212.3 6.8 1.0 1 0 0 1 1 1 1 G10 protein zf-C2H2 PF00096.26 ETS79947.1 - 0.097 13.2 13.2 0.29 11.7 2.8 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS79947.1 - 8.5 7.5 11.8 0.57 11.2 2.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger EST1_DNA_bind PF10373.9 ETS79948.1 - 2.2e-39 135.7 0.1 3.4e-39 135.0 0.1 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 ETS79948.1 - 4e-21 76.1 0.4 1.2e-20 74.5 0.4 1.9 1 0 0 1 1 1 1 Telomerase activating protein Est1 PfkB PF00294.24 ETS79949.1 - 1.9e-65 221.2 0.3 2.1e-65 221.0 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 ETS79949.1 - 0.0099 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Ribosomal_L2_C PF03947.18 ETS79950.1 - 8.1e-42 142.4 4.9 8.1e-42 142.4 4.9 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ETS79950.1 - 2.4e-14 53.0 0.1 6.3e-14 51.7 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain RRM_1 PF00076.22 ETS79951.1 - 7.5e-06 25.7 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUIM_assoc PF16619.5 ETS79951.1 - 0.0014 18.7 1.3 0.0043 17.1 0.2 2.3 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 ETS79951.1 - 0.73 9.4 4.8 1.2 8.7 4.8 1.3 1 0 0 1 1 1 0 Spt20 family FTZ PF03867.14 ETS79951.1 - 2.7 7.5 5.7 0.43 10.1 1.7 1.6 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region Pkinase PF00069.25 ETS79952.1 - 1.2e-49 169.1 0.1 3.8e-49 167.4 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS79952.1 - 2.9e-23 82.5 0.0 5.2e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ETS79952.1 - 0.00015 21.7 1.4 0.00033 20.7 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 ETS79952.1 - 0.0029 17.2 0.2 0.0072 15.9 0.2 1.6 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 ETS79952.1 - 0.27 10.8 1.4 0.38 10.3 0.2 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase RRM_1 PF00076.22 ETS79953.1 - 1.7e-62 207.1 0.0 1.3e-21 76.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ETS79953.1 - 3.1e-11 42.9 0.0 2.6e-05 23.8 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ETS79953.1 - 9.7e-10 38.2 0.0 0.0013 18.5 0.0 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 ETS79953.1 - 2.8e-06 27.2 0.0 0.029 14.4 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 ETS79953.1 - 0.0011 18.9 0.0 0.61 10.2 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_7 PF16367.5 ETS79953.1 - 0.0014 18.7 0.0 1.5 9.0 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif RRM_8 PF11835.8 ETS79953.1 - 0.0022 18.2 0.0 0.41 10.9 0.0 2.3 2 0 0 2 2 2 1 RRM-like domain RNA_bind PF08675.11 ETS79953.1 - 0.018 15.1 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 RNA binding domain SET_assoc PF11767.8 ETS79953.1 - 0.084 12.5 0.0 10 5.9 0.0 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_3 PF08777.11 ETS79953.1 - 0.18 11.8 0.0 3.1 7.9 0.0 2.4 3 0 0 3 3 3 0 RNA binding motif BRAP2 PF07576.12 ETS79953.1 - 0.24 11.6 0.0 1.6 9.0 0.0 2.1 2 0 0 2 2 2 0 BRCA1-associated protein 2 Aldo_ket_red PF00248.21 ETS79955.1 - 9.6e-61 205.5 0.0 1.1e-60 205.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2016 PF09436.10 ETS79955.1 - 0.078 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2016) DUF3425 PF11905.8 ETS79956.1 - 1.7e-19 70.0 0.2 3.8e-19 68.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 ETS79956.1 - 0.91 9.7 8.4 1.7 8.8 8.4 1.4 1 0 0 1 1 1 0 bZIP transcription factor FAD_binding_4 PF01565.23 ETS79957.1 - 7e-17 61.5 0.1 1.5e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS79957.1 - 0.087 12.9 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like Cellulase PF00150.18 ETS79958.1 - 8.3e-17 61.5 2.6 1.7e-16 60.5 2.2 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PH PF00169.29 ETS79959.1 - 4.2e-28 97.9 1.6 5.2e-16 59.0 0.3 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 ETS79959.1 - 2e-12 47.4 3.7 8.1e-06 26.2 1.2 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 ETS79959.1 - 1.9e-11 44.4 3.5 2.5e-05 24.6 1.0 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 ETS79959.1 - 2.5e-05 24.5 0.1 6.3e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 ETS79959.1 - 0.0002 21.4 1.1 0.0071 16.4 0.2 2.5 2 1 0 2 2 2 1 PH domain PH_13 PF16652.5 ETS79959.1 - 0.05 13.4 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Tmemb_170 PF10190.9 ETS79961.1 - 5.1e-26 91.1 15.2 5.9e-26 90.9 15.2 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 Hexapep_2 PF14602.6 ETS79962.1 - 7.8e-14 51.1 10.3 8.4e-11 41.4 4.2 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 ETS79962.1 - 1.3e-11 43.8 12.0 6.1e-09 35.3 4.6 3.5 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 ETS79962.1 - 9.3e-10 38.6 0.3 1.6e-09 37.9 0.3 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase AHJR-like PF18743.1 ETS79962.1 - 0.24 11.0 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 REase_AHJR-like ICMT PF04140.14 ETS79963.1 - 6.1e-28 97.1 0.4 6.1e-28 97.1 0.4 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 ETS79963.1 - 5e-15 55.8 1.6 5e-15 55.8 1.6 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 ETS79963.1 - 1e-06 28.4 1.3 1.6e-06 27.8 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 ETS79963.1 - 1.2e-05 24.3 1.7 1.7e-05 23.8 0.2 1.8 1 1 1 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family DUF973 PF06157.11 ETS79963.1 - 0.049 12.7 0.4 0.082 12.0 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF973) Ank_2 PF12796.7 ETS79964.1 - 8.1e-85 279.5 27.1 1e-17 64.4 0.8 12.8 3 2 8 12 12 12 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS79964.1 - 2.1e-70 231.8 27.5 2.4e-11 43.7 0.2 11.8 3 2 6 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 ETS79964.1 - 4.7e-68 222.9 38.6 1.4e-06 28.5 0.0 15.7 17 0 0 17 17 14 12 Ankyrin repeat Ank_4 PF13637.6 ETS79964.1 - 6.6e-64 211.5 19.1 1.4e-08 35.1 0.0 11.3 4 2 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS79964.1 - 1.7e-61 196.9 18.3 0.00022 21.4 0.0 16.8 16 0 0 16 16 15 11 Ankyrin repeat PNP_UDP_1 PF01048.20 ETS79964.1 - 2.7e-14 53.0 0.0 5.6e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 ETS79964.1 - 1.1e-10 41.7 0.0 2.7e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS79964.1 - 6.2e-08 33.2 0.1 3.3e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 ETS79964.1 - 0.00011 22.6 0.0 0.00084 19.8 0.0 2.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 ETS79964.1 - 0.001 18.3 0.0 0.0026 17.0 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.6 ETS79964.1 - 0.0039 17.2 0.0 0.037 14.1 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ETS79964.1 - 0.012 15.9 0.0 0.067 13.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ETS79964.1 - 0.019 15.4 0.0 0.047 14.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 ETS79964.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Helicase_C_3 PF13625.6 ETS79964.1 - 0.071 13.3 0.2 1.9 8.6 0.0 3.3 3 1 0 3 3 2 0 Helicase conserved C-terminal domain Shigella_OspC PF06128.11 ETS79964.1 - 0.09 12.5 0.0 4.5 6.9 0.0 3.1 3 0 0 3 3 3 0 Shigella flexneri OspC protein PDEase_I PF00233.19 ETS79965.1 - 1.6e-67 227.7 0.0 2.3e-67 227.2 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF3669 PF12417.8 ETS79966.1 - 1.6e-08 34.6 0.0 3.5e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Zinc finger protein Myb_DNA-bind_7 PF15963.5 ETS79967.1 - 7.1e-25 86.7 0.2 2.2e-24 85.1 0.2 1.8 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 ETS79967.1 - 7.2e-07 29.3 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ETS79967.1 - 0.00018 21.7 0.0 0.00035 20.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain BRE1 PF08647.11 ETS79968.1 - 7.2e-20 70.9 10.8 7.2e-20 70.9 10.8 6.5 4 3 2 6 6 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 ETS79968.1 - 1.3e-07 31.3 9.8 2.1e-07 30.7 9.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS79968.1 - 3.6e-07 30.1 7.2 6.7e-07 29.2 7.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ETS79968.1 - 4.1e-07 29.8 8.9 6.8e-07 29.0 8.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 ETS79968.1 - 7.4e-07 28.9 10.0 1.3e-06 28.1 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ETS79968.1 - 8.6e-07 28.7 13.4 1.6e-06 27.9 13.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ETS79968.1 - 1.9e-06 27.7 13.0 3.4e-06 26.9 13.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 ETS79968.1 - 2.1e-06 27.9 10.6 3.7e-06 27.2 10.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 ETS79968.1 - 0.0014 18.7 7.5 0.0028 17.8 7.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 ETS79968.1 - 0.007 16.2 4.0 0.015 15.1 4.0 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 ETS79968.1 - 0.019 14.7 7.5 0.051 13.4 7.5 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 ETS79968.1 - 0.069 13.3 4.2 0.21 11.7 4.2 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_10 PF16685.5 ETS79968.1 - 0.16 12.1 5.9 0.44 10.7 5.9 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Nas2_N PF18265.1 ETS79968.1 - 0.17 11.8 0.1 0.17 11.8 0.1 5.1 3 1 1 4 4 4 0 Nas2 N_terminal domain zf-rbx1 PF12678.7 ETS79968.1 - 0.31 11.3 9.4 1.1 9.6 9.4 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-Nse PF11789.8 ETS79968.1 - 0.38 10.6 6.6 0.84 9.5 6.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-CHY PF05495.12 ETS79968.1 - 1 9.9 8.3 5.8 7.5 7.0 2.4 2 0 0 2 2 2 0 CHY zinc finger zf-C2H2_4 PF13894.6 ETS79968.1 - 1.2 10.1 3.9 24 6.1 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger FYVE PF01363.21 ETS79968.1 - 1.8 8.7 12.4 14 5.9 12.6 2.3 1 1 1 2 2 2 0 FYVE zinc finger DUF4407 PF14362.6 ETS79968.1 - 2.2 7.6 60.2 19 4.5 30.5 3.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4407) zf-RING_11 PF17123.5 ETS79968.1 - 9.4 6.1 8.1 23 4.9 8.1 1.7 1 0 0 1 1 1 0 RING-like zinc finger SARAF PF06682.12 ETS79969.1 - 2.4e-99 333.1 6.4 2.9e-99 332.9 6.4 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis p450 PF00067.22 ETS79970.1 - 6.8e-48 163.6 0.1 1.6e-47 162.4 0.0 1.5 1 1 1 2 2 2 1 Cytochrome P450 Pkinase PF00069.25 ETS79971.1 - 2.2e-71 240.3 0.0 2.9e-71 239.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS79971.1 - 4.6e-44 150.6 0.0 6.7e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS79971.1 - 8.5e-08 31.8 0.0 4.1e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 ETS79971.1 - 0.0013 18.1 0.1 0.0024 17.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ETS79971.1 - 0.021 14.5 0.0 0.17 11.4 0.0 2.1 1 1 1 2 2 2 0 RIO1 family Levi_coat PF01819.17 ETS79971.1 - 0.027 14.5 1.2 3.3 7.7 1.0 2.3 2 0 0 2 2 2 0 Levivirus coat protein FTA2 PF13095.6 ETS79971.1 - 0.059 13.0 0.0 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 ETS79971.1 - 0.061 12.8 0.1 0.17 11.4 0.1 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 ETS79971.1 - 0.071 13.0 0.1 0.12 12.3 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ETS79971.1 - 0.17 10.8 6.3 3.4 6.5 6.3 2.1 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 ETS79971.1 - 0.37 9.5 2.1 0.6 8.8 2.1 1.5 1 1 0 1 1 1 0 Fungal protein kinase Peptidase_M76 PF09768.9 ETS79972.1 - 2.2e-34 118.7 0.1 2.9e-34 118.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 ETS79972.1 - 0.0093 15.8 2.0 0.015 15.2 1.7 1.4 1 1 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 ETS79972.1 - 0.071 13.4 0.1 0.094 13.0 0.1 1.3 1 0 0 1 1 1 0 Effector protein AA_kinase PF00696.28 ETS79973.1 - 4e-39 134.7 1.3 5.4e-39 134.2 1.3 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 ETS79973.1 - 7e-13 48.3 1.2 1.8e-12 47.0 0.1 2.2 2 0 0 2 2 2 1 PUA domain CsbD PF05532.12 ETS79974.1 - 0.059 13.3 0.5 0.11 12.4 0.5 1.4 1 0 0 1 1 1 0 CsbD-like Fungal_trans PF04082.18 ETS79975.1 - 2.2e-10 40.0 0.3 3e-10 39.6 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.7 ETS79976.1 - 5.6e-60 199.9 0.0 4.8e-14 52.7 0.0 6.3 2 1 6 8 8 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS79976.1 - 1e-32 112.1 0.2 7.9e-08 32.7 0.0 7.1 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS79976.1 - 1.2e-30 105.2 5.4 3.3e-07 30.4 0.0 8.3 4 2 6 10 10 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS79976.1 - 1.9e-27 92.3 0.2 0.014 15.9 0.0 10.4 10 0 0 10 10 10 6 Ankyrin repeat Ank PF00023.30 ETS79976.1 - 1.9e-27 94.4 0.0 0.002 18.5 0.0 10.2 10 0 0 10 10 10 5 Ankyrin repeat Abhydrolase_6 PF12697.7 ETS79976.1 - 4.3e-05 24.2 0.4 0.00013 22.6 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ETS79976.1 - 5.2e-05 23.1 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 ETS79976.1 - 7.5e-05 22.3 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) NACHT PF05729.12 ETS79976.1 - 0.00011 22.2 0.0 0.0008 19.4 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 ETS79976.1 - 0.00069 20.0 0.1 0.0091 16.4 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ETS79976.1 - 0.0033 17.7 0.0 0.023 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 ETS79976.1 - 0.0057 16.6 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase KAP_NTPase PF07693.14 ETS79976.1 - 0.047 12.9 0.5 4.9 6.3 0.3 2.4 1 1 1 2 2 2 0 KAP family P-loop domain TrwB_AAD_bind PF10412.9 ETS79976.1 - 0.054 12.4 0.0 0.92 8.4 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain 6PF2K PF01591.18 ETS79976.1 - 0.071 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_18 PF13238.6 ETS79976.1 - 0.09 13.3 0.9 0.24 11.9 0.0 2.3 3 0 0 3 3 1 0 AAA domain Ploopntkinase3 PF18751.1 ETS79976.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Hydrolase_4 PF12146.8 ETS79976.1 - 0.14 11.4 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RNA_helicase PF00910.22 ETS79976.1 - 0.16 12.4 0.0 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase MFS_1 PF07690.16 ETS79977.1 - 3.8e-33 114.9 14.4 3.8e-33 114.9 14.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ETS79977.1 - 2.8e-08 33.5 0.3 7.1e-08 32.1 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB AAT PF03417.16 ETS79978.1 - 6.9e-28 97.9 0.0 8.5e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Penicil_amidase PF01804.18 ETS79978.1 - 0.21 10.5 0.0 0.29 10.0 0.0 1.1 1 0 0 1 1 1 0 Penicillin amidase Polysacc_deac_1 PF01522.21 ETS79979.1 - 2.8e-17 62.8 0.0 4.2e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ETS79979.1 - 1.1e-11 44.9 0.2 1.8e-11 44.1 0.2 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 ETS79979.1 - 2.8e-06 26.8 0.2 5.2e-06 25.9 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 DUF2194 PF09960.9 ETS79979.1 - 0.03 12.7 0.1 0.044 12.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) adh_short_C2 PF13561.6 ETS79980.1 - 2.6e-44 151.6 0.3 1.7e-43 148.9 0.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS79980.1 - 1.5e-33 115.9 0.1 3.8e-33 114.6 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 ETS79980.1 - 1.2e-07 31.5 0.0 2.9e-06 26.9 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ETS79980.1 - 6e-06 26.3 0.3 1.9e-05 24.6 0.3 1.8 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 ETS79980.1 - 0.0023 17.0 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ETS79980.1 - 0.0097 15.3 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Tobravirus_2B PF05271.11 ETS79980.1 - 0.033 14.1 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Tobravirus 2B protein RmlD_sub_bind PF04321.17 ETS79980.1 - 0.042 13.0 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 ETS79981.1 - 8.6e-37 126.5 0.0 1.1e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS79981.1 - 1.1e-31 110.2 0.1 1.4e-31 109.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ETS79981.1 - 0.0002 20.9 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ETS79981.1 - 0.00031 20.7 0.5 0.0014 18.5 0.2 2.0 2 0 0 2 2 2 1 KR domain Ldh_1_N PF00056.23 ETS79981.1 - 0.011 15.8 0.1 0.021 14.9 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Acyltransferase PF01553.21 ETS79982.1 - 4.9e-34 116.9 0.0 7.7e-34 116.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF4281 PF14108.6 ETS79982.1 - 0.022 15.1 1.8 0.05 14.0 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) Phage_holin_3_6 PF07332.11 ETS79982.1 - 4.6 7.3 9.6 9.3 6.3 9.6 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III AP_endonuc_2 PF01261.24 ETS79985.1 - 5.9e-25 87.9 0.0 7.7e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel adh_short_C2 PF13561.6 ETS79986.1 - 1.8e-56 191.4 0.0 2.1e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS79986.1 - 3.9e-45 153.7 0.0 4.7e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS79986.1 - 3.2e-10 40.2 0.1 4.5e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS79986.1 - 9e-05 21.7 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 ETS79986.1 - 0.0038 16.6 0.0 0.0061 15.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 ETS79986.1 - 0.0045 16.5 0.0 0.0067 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 ETS79986.1 - 0.011 15.6 0.0 0.039 13.9 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 ETS79986.1 - 0.026 15.2 0.0 0.063 14.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 ETS79986.1 - 0.031 14.1 0.0 0.082 12.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Ldh_1_N PF00056.23 ETS79986.1 - 0.053 13.6 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 ETS79986.1 - 0.061 12.6 0.0 2.1 7.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 ETS79986.1 - 0.094 13.2 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 ETS79986.1 - 0.16 12.3 0.0 0.52 10.6 0.0 1.9 2 1 0 2 2 2 0 TrkA-N domain GDP_Man_Dehyd PF16363.5 ETS79986.1 - 0.2 11.0 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sugar_tr PF00083.24 ETS79987.1 - 7.6e-100 334.9 32.9 9.2e-66 222.5 8.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ETS79987.1 - 6.9e-20 71.3 45.2 2.4e-10 39.9 22.0 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily PX PF00787.24 ETS79988.1 - 2.3e-19 69.5 0.0 5.4e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 ETS79988.1 - 5e-14 52.4 11.0 2.3e-08 33.9 0.7 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3_WASP_bdg PF10456.9 ETS79988.1 - 0.025 14.0 0.1 0.4 10.1 0.2 2.2 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein DUF1104 PF06518.11 ETS79988.1 - 8.6 6.8 7.7 1.5 9.2 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Asp PF00026.23 ETS79989.1 - 9.6e-74 248.6 6.5 1.3e-73 248.2 6.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS79989.1 - 2.2e-11 44.3 10.0 4.3e-11 43.4 3.2 3.9 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ETS79989.1 - 1.3e-06 28.9 3.9 0.34 11.6 0.0 4.3 4 1 1 5 5 5 2 Aspartyl protease TAXi_C PF14541.6 ETS79989.1 - 0.0014 18.4 0.0 0.0042 16.9 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 ETS79989.1 - 0.002 18.7 1.6 9.4 6.9 0.0 4.2 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease Glyco_tranf_2_4 PF13704.6 ETS79990.1 - 2.8e-12 47.0 0.4 7.8e-12 45.6 0.0 2.0 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 ETS79990.1 - 0.004 16.8 0.0 0.017 14.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 92 AbrB_C PF18277.1 ETS79990.1 - 0.055 13.1 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 AbrB C-terminal domain TPT PF03151.16 ETS79991.1 - 8.3e-07 28.6 18.7 1.7e-06 27.7 18.7 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ETS79991.1 - 2.8e-05 24.3 14.3 2.8e-05 24.3 14.3 2.2 2 0 0 2 2 2 1 EamA-like transporter family GDP_Man_Dehyd PF16363.5 ETS79992.1 - 2.6e-68 230.9 0.0 3.2e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ETS79992.1 - 1.1e-55 188.8 0.0 1.4e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ETS79992.1 - 4.9e-23 81.7 0.0 4.5e-22 78.5 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ETS79992.1 - 7.4e-20 71.1 0.0 1e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ETS79992.1 - 6.6e-19 68.1 0.1 8.8e-18 64.4 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 ETS79992.1 - 4.4e-17 62.1 0.0 5.6e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 ETS79992.1 - 3.3e-06 27.1 0.0 6.3e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 ETS79992.1 - 0.087 12.3 0.0 5 6.5 0.1 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Methyltransf_23 PF13489.6 ETS79993.1 - 1.2e-15 57.7 0.0 2.1e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS79993.1 - 1.4e-11 45.0 0.0 3.4e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS79993.1 - 2.2e-11 44.3 0.0 5.7e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS79993.1 - 7.3e-08 33.0 0.0 1.6e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS79993.1 - 2.5e-07 30.6 0.0 7.4e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ETS79993.1 - 0.00065 19.1 0.0 0.0023 17.2 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_4 PF02390.17 ETS79993.1 - 0.00073 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 ETS79993.1 - 0.0014 18.0 0.0 0.0057 16.0 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ETS79993.1 - 0.02 14.4 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 ETS79993.1 - 0.047 13.4 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 ETS79993.1 - 0.081 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.12 ETS79993.1 - 0.097 12.4 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Pep3_Vps18 PF05131.14 ETS79994.1 - 2e-47 160.7 1.1 3.6e-47 159.9 0.0 2.0 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 ETS79994.1 - 2.2e-09 37.3 11.6 2.2e-07 30.9 0.2 3.5 2 1 0 2 2 2 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 ETS79994.1 - 0.0003 20.3 0.6 0.00061 19.4 0.6 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 ETS79994.1 - 0.00069 19.5 1.8 0.0016 18.4 1.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ETS79994.1 - 0.00082 19.2 1.0 0.0018 18.0 1.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ETS79994.1 - 0.0025 18.1 1.4 0.006 16.9 1.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ETS79994.1 - 0.0071 16.1 4.0 0.0071 16.1 4.0 2.0 2 0 0 2 2 2 1 RING-like zinc finger Vps39_2 PF10367.9 ETS79994.1 - 0.0094 16.4 0.0 0.034 14.6 0.0 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 DUF2175 PF09943.9 ETS79994.1 - 0.021 15.1 0.4 0.021 15.1 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-rbx1 PF12678.7 ETS79994.1 - 0.051 13.9 0.2 0.13 12.5 0.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ETS79994.1 - 0.069 13.2 2.0 0.16 12.1 2.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger dCMP_cyt_deam_2 PF08211.12 ETS79994.1 - 0.1 12.8 0.0 2.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region SopA PF13981.6 ETS79994.1 - 0.13 12.7 1.7 5 7.6 0.0 2.9 3 0 0 3 3 2 0 SopA-like central domain zf-C3H2C3 PF17122.5 ETS79994.1 - 0.22 11.6 2.2 0.5 10.5 2.2 1.6 1 0 0 1 1 1 0 Zinc-finger THOC7 PF05615.13 ETS79994.1 - 0.63 10.3 4.5 27 5.0 2.7 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 zf-C3HC4 PF00097.25 ETS79994.1 - 4.4 7.3 6.5 0.42 10.5 1.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PUF PF00806.19 ETS79996.1 - 3.4e-27 92.6 0.0 0.00014 21.3 0.0 5.8 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 ETS79996.1 - 3.2e-13 49.3 0.0 7e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Importin_rep_6 PF18829.1 ETS79996.1 - 0.16 12.1 1.2 0.47 10.6 1.2 1.7 1 0 0 1 1 1 0 Importin repeat 6 PHD PF00628.29 ETS79997.1 - 6.3e-13 48.4 23.4 4.6e-09 36.0 9.5 2.4 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 ETS79997.1 - 0.013 15.1 9.1 0.23 11.1 1.6 2.9 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 ETS79997.1 - 0.18 11.4 12.4 0.21 11.2 4.1 2.7 2 0 0 2 2 2 0 PHD-finger Peptidase_M24 PF00557.24 ETS79998.1 - 9e-08 32.0 0.0 1.7e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 AP3D1 PF06375.11 ETS79998.1 - 0.52 10.5 10.4 0.15 12.3 6.9 1.9 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 SNF5 PF04855.12 ETS79999.1 - 1.3e-64 218.3 0.2 3e-63 213.8 0.2 2.3 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 INO80_Ies4 PF08193.11 ETS79999.1 - 0.0017 18.4 7.6 0.0017 18.4 7.6 3.1 2 1 1 3 3 3 1 INO80 complex subunit Ies4 adh_short PF00106.25 ETS80000.1 - 2.7e-32 111.8 0.2 7.1e-23 81.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS80000.1 - 1.3e-23 83.8 0.2 1.7e-19 70.3 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 ETS80000.1 - 0.0015 18.0 0.0 0.0023 17.4 0.0 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 ETS80000.1 - 0.0024 17.8 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 ETS80000.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 ETS80000.1 - 0.13 12.1 0.8 0.98 9.3 0.6 2.4 1 1 0 1 1 1 0 NAD(P)H-binding DSBA PF01323.20 ETS80001.1 - 2.2e-13 50.4 0.0 5.6e-06 26.3 0.0 2.0 2 0 0 2 2 2 2 DSBA-like thioredoxin domain CENP-H PF05837.12 ETS80002.1 - 0.01 16.2 4.4 0.018 15.4 4.4 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) TraT PF05818.12 ETS80002.1 - 0.043 13.5 3.5 0.066 12.9 3.5 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Gp-FAR-1 PF05823.12 ETS80002.1 - 0.08 13.3 3.7 0.11 12.8 3.7 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Ubiquitin_5 PF18037.1 ETS80002.1 - 0.081 13.3 0.5 0.081 13.3 0.5 1.5 2 0 0 2 2 1 0 Ubiquitin-like domain MCU PF04678.13 ETS80002.1 - 0.084 13.0 0.9 0.12 12.4 0.9 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter HhH-GPD PF00730.25 ETS80002.1 - 0.11 12.9 0.2 0.16 12.4 0.2 1.4 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein Spectrin PF00435.21 ETS80002.1 - 0.16 12.5 7.2 0.25 11.9 7.2 1.3 1 0 0 1 1 1 0 Spectrin repeat DUF4337 PF14235.6 ETS80002.1 - 0.4 10.8 3.3 0.66 10.1 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4407 PF14362.6 ETS80002.1 - 1.5 8.1 8.3 2 7.7 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Synaptobrevin PF00957.21 ETS80002.1 - 1.5 8.6 3.8 16 5.4 0.3 2.3 1 1 1 2 2 2 0 Synaptobrevin Mod_r PF07200.13 ETS80002.1 - 2 8.5 12.0 0.1 12.7 6.6 1.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Gly-zipper_YMGG PF13441.6 ETS80002.1 - 5.8 6.7 35.0 12 5.7 20.5 2.2 1 1 1 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 ETS80002.1 - 8.9 6.4 36.1 0.3 11.1 16.2 2.2 1 1 1 2 2 2 0 Glycine zipper 4HB_MCP_1 PF12729.7 ETS80003.1 - 0.48 9.9 5.8 0.79 9.2 5.8 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Dsh_C PF12316.8 ETS80003.1 - 4.2 7.7 17.1 0.85 10.0 10.2 2.4 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal APG6_N PF17675.1 ETS80003.1 - 4.5 7.8 16.7 0.52 10.8 10.2 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF2040 PF09745.9 ETS80004.1 - 8.1e-40 135.6 19.0 8.1e-40 135.6 19.0 3.9 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) zf-Tim10_DDP PF02953.15 ETS80005.1 - 1.5e-22 79.0 1.3 1.8e-22 78.7 1.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DDE_1 PF03184.19 ETS80005.1 - 0.065 12.9 0.0 0.082 12.6 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Lectin_leg-like PF03388.13 ETS80006.1 - 2.6e-65 220.0 0.0 3.2e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 ETS80006.1 - 2e-05 24.3 0.0 0.04 13.4 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain Pkinase PF00069.25 ETS80007.1 - 8.2e-74 248.3 0.0 1.3e-73 247.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS80007.1 - 1.9e-38 132.3 0.0 2.8e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS80007.1 - 1.8e-08 34.0 0.0 3.6e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like TFIIA PF03153.13 ETS80007.1 - 0.017 15.2 30.9 0.022 14.7 30.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 ETS80007.1 - 1.6 7.8 24.7 2.2 7.4 24.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CorA PF01544.18 ETS80008.1 - 2.2e-06 27.2 2.0 5.7e-06 25.9 0.2 2.3 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Dioxygenase_N PF04444.14 ETS80008.1 - 0.029 14.2 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 Catechol dioxygenase N terminus Dynamin_N PF00350.23 ETS80009.1 - 1.1e-16 61.3 0.1 1.5e-15 57.6 0.0 3.0 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 ETS80009.1 - 9e-08 32.2 0.0 0.00014 21.9 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETS80009.1 - 0.00014 21.8 0.3 0.0019 18.1 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase Zeta_toxin PF06414.12 ETS80009.1 - 0.00034 20.0 4.3 0.0028 16.9 0.0 3.7 4 0 0 4 4 4 1 Zeta toxin ABC_tran PF00005.27 ETS80009.1 - 0.0047 17.4 1.4 0.014 15.9 0.2 2.5 2 1 0 2 2 2 1 ABC transporter IIGP PF05049.13 ETS80009.1 - 0.014 14.5 0.3 0.032 13.3 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) TrbI_Ftype PF09677.10 ETS80009.1 - 0.025 14.9 1.3 3.2 8.1 0.2 4.3 4 0 0 4 4 4 0 Type-F conjugative transfer system protein (TrbI_Ftype) AAA_16 PF13191.6 ETS80009.1 - 0.039 14.3 0.1 0.24 11.8 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain GBP PF02263.19 ETS80009.1 - 0.044 13.0 0.0 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain AAA_7 PF12775.7 ETS80009.1 - 0.055 13.0 0.0 8.8 5.8 0.0 3.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Adeno_IVa2 PF02456.15 ETS80009.1 - 0.085 11.6 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF2605 PF10792.9 ETS80009.1 - 6.2 6.8 10.2 20 5.2 0.2 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2605) ELO PF01151.18 ETS80010.1 - 7.8e-83 277.8 9.1 9.7e-83 277.5 9.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family FYVE PF01363.21 ETS80011.1 - 1.3e-14 54.0 8.9 2.4e-14 53.2 8.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 ETS80011.1 - 0.023 14.8 8.2 0.023 14.8 8.2 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger Spt20 PF12090.8 ETS80011.1 - 2.6 7.6 7.6 4.6 6.8 7.6 1.3 1 0 0 1 1 1 0 Spt20 family Zn-ribbon_8 PF09723.10 ETS80011.1 - 2.8 8.1 7.1 3.5 7.8 0.1 2.7 2 1 0 2 2 2 0 Zinc ribbon domain MoaC PF01967.21 ETS80012.1 - 2.3e-53 179.9 4.6 3.7e-53 179.3 4.6 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 ETS80012.1 - 1.7e-37 128.2 0.1 5.1e-36 123.4 0.0 2.3 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 ETS80012.1 - 4.5e-26 92.2 0.0 9.1e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 ETS80012.1 - 1.7e-05 25.1 0.0 0.00015 22.1 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 ETS80012.1 - 0.05 13.7 0.0 0.19 11.9 0.0 2.0 1 0 0 1 1 1 0 4Fe-4S single cluster domain WD40 PF00400.32 ETS80013.1 - 0.042 14.7 2.1 55 4.9 0.1 4.9 4 0 0 4 4 4 0 WD domain, G-beta repeat RRM_1 PF00076.22 ETS80014.1 - 1.3e-08 34.5 0.0 2.1e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dynamin_N PF00350.23 ETS80015.1 - 5.2e-16 59.1 0.0 4.5e-15 56.1 0.0 2.7 1 1 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 ETS80015.1 - 0.00016 22.2 0.3 0.01 16.3 0.0 3.0 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.23 ETS80015.1 - 0.00035 20.6 0.1 0.0051 16.9 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Adeno_IVa2 PF02456.15 ETS80015.1 - 0.0015 17.4 0.0 0.0028 16.5 0.0 1.4 1 0 0 1 1 1 1 Adenovirus IVa2 protein RsgA_GTPase PF03193.16 ETS80015.1 - 0.0015 18.5 0.1 0.041 13.8 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase DHR10 PF18595.1 ETS80015.1 - 0.018 15.1 0.7 0.018 15.1 0.7 3.3 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain KAP_NTPase PF07693.14 ETS80015.1 - 0.023 13.9 0.0 1.8 7.8 0.0 2.6 2 0 0 2 2 2 0 KAP family P-loop domain Zeta_toxin PF06414.12 ETS80015.1 - 0.048 12.9 0.1 0.94 8.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 ETS80015.1 - 0.057 13.8 0.5 0.6 10.5 0.1 3.1 2 1 1 3 3 3 0 AAA ATPase domain DUF1722 PF08349.11 ETS80015.1 - 0.059 13.7 0.2 1.7 9.0 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF87 PF01935.17 ETS80015.1 - 0.061 13.4 5.4 0.66 10.0 0.1 3.6 2 1 1 3 3 3 0 Helicase HerA, central domain CDC37_M PF08565.11 ETS80015.1 - 0.088 12.7 1.8 0.24 11.3 0.5 2.4 2 0 0 2 2 2 0 Cdc37 Hsp90 binding domain Roc PF08477.13 ETS80015.1 - 0.11 12.7 0.0 0.85 9.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PG_binding_1 PF01471.18 ETS80015.1 - 0.12 12.6 0.0 0.48 10.7 0.0 2.1 2 0 0 2 2 1 0 Putative peptidoglycan binding domain AAA_29 PF13555.6 ETS80015.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 ETS80015.1 - 0.35 11.1 1.3 9.9 6.4 0.0 3.6 3 1 1 4 4 4 0 AAA domain NUDIX_2 PF13869.6 ETS80016.1 - 5e-80 267.5 0.0 5.9e-80 267.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase UPF0047 PF01894.17 ETS80017.1 - 5e-33 113.7 0.0 3.6e-32 110.9 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised protein family UPF0047 DUF3328 PF11807.8 ETS80017.1 - 0.036 13.9 0.9 0.052 13.3 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) zf-CHCC PF10276.9 ETS80018.1 - 2.9e-15 56.0 1.2 4.7e-15 55.4 1.2 1.3 1 0 0 1 1 1 1 Zinc-finger domain zf-CCHC PF00098.23 ETS80019.1 - 7.1e-06 25.9 4.3 1.4e-05 24.9 4.3 1.5 1 0 0 1 1 1 1 Zinc knuckle MPP6 PF10175.9 ETS80019.1 - 0.0022 18.5 3.1 0.0022 18.5 3.1 2.8 2 2 0 2 2 2 1 M-phase phosphoprotein 6 HalOD2 PF18547.1 ETS80019.1 - 0.045 13.7 0.3 0.097 12.6 0.3 1.5 1 0 0 1 1 1 0 Halobacterial output domain 2 zf-CCHC_4 PF14392.6 ETS80019.1 - 0.14 11.9 1.8 0.28 11.0 1.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Peptidase_M16_M PF16187.5 ETS80020.1 - 2.2e-97 325.7 0.6 3.4e-97 325.1 0.6 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 ETS80020.1 - 4.7e-35 120.8 0.1 1.3e-34 119.3 0.1 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ETS80020.1 - 2.9e-26 92.6 0.1 5.1e-15 56.0 0.0 3.1 4 0 0 4 4 4 2 Peptidase M16 inactive domain HsbA PF12296.8 ETS80021.1 - 8.3e-12 45.6 10.4 8.3e-12 45.6 10.4 3.6 2 2 1 4 4 4 1 Hydrophobic surface binding protein A Spore_YunB PF09560.10 ETS80021.1 - 0.16 12.0 1.7 6.7 6.8 0.0 3.3 3 0 0 3 3 3 0 Sporulation protein YunB (Spo_YunB) NPV_P10 PF05531.12 ETS80021.1 - 0.22 12.0 1.9 0.87 10.1 1.5 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein LPP PF04728.13 ETS80021.1 - 0.94 9.9 4.0 2 8.8 1.9 2.6 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Toxin_30 PF08117.11 ETS80022.1 - 1.3 9.3 12.0 1.3 9.4 0.8 3.3 3 0 0 3 3 3 0 Ptu family Kdo PF06293.14 ETS80024.1 - 0.01 15.2 2.9 0.024 14.0 2.8 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIP PF00230.20 ETS80025.1 - 5.9e-42 143.9 7.2 7.5e-42 143.6 7.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF1761 PF08570.10 ETS80025.1 - 1 9.6 10.9 0.31 11.3 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1761) Fungal_trans_2 PF11951.8 ETS80026.1 - 1.9e-23 82.9 1.3 2.6e-23 82.5 1.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS80026.1 - 0.0022 18.1 13.2 0.0057 16.8 13.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 ETS80027.1 - 3.1e-34 118.4 12.9 6.1e-34 117.4 12.9 1.5 1 1 0 1 1 1 1 RTA1 like protein adh_short PF00106.25 ETS80029.1 - 1.5e-11 44.1 0.0 1.7e-08 34.2 0.0 2.9 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 ETS80029.1 - 1.6e-07 31.4 0.0 2.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS80029.1 - 0.052 13.0 0.1 0.19 11.1 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS80029.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding p450 PF00067.22 ETS80031.1 - 3.5e-35 121.7 0.0 2.4e-20 72.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 adh_short PF00106.25 ETS80032.1 - 1.2e-30 106.4 0.1 8.6e-23 80.8 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS80032.1 - 1e-15 57.9 0.0 1.4e-11 44.4 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS80032.1 - 5.5e-08 32.9 0.0 8.9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ETS80032.1 - 0.098 12.5 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_4 PF07993.12 ETS80032.1 - 0.11 11.6 0.1 0.22 10.6 0.1 1.7 1 1 0 1 1 1 0 Male sterility protein Ferric_reduct PF01794.19 ETS80033.1 - 4.1e-20 72.2 15.4 4.1e-20 72.2 15.4 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ETS80033.1 - 5.2e-15 55.9 0.0 9.3e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Pec_lyase_C PF00544.19 ETS80033.1 - 1.3e-12 47.8 6.6 3.1e-11 43.3 6.6 2.3 1 1 0 1 1 1 1 Pectate lyase FAD_binding_8 PF08022.12 ETS80033.1 - 8.9e-10 38.6 0.0 1.9e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.6 ETS80033.1 - 0.013 16.1 1.1 0.013 16.1 1.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4405) NPV_P10 PF05531.12 ETS80034.1 - 1.6 9.2 5.6 2.2 8.8 1.6 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA PF00004.29 ETS80035.1 - 1.2e-19 71.1 0.0 1.7e-16 60.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ETS80035.1 - 5.7e-06 26.4 0.0 0.097 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ETS80035.1 - 0.00023 21.6 0.1 0.0067 16.8 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain MeaB PF03308.16 ETS80035.1 - 0.0045 16.0 0.2 0.55 9.2 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 ETS80035.1 - 0.033 14.5 0.9 0.96 9.7 0.1 3.3 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.6 ETS80035.1 - 0.038 14.5 1.1 2.3 8.8 0.7 3.4 2 1 0 2 2 2 0 AAA domain CPT PF07931.12 ETS80035.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.6 ETS80035.1 - 0.34 11.3 1.6 13 6.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF1275 PF06912.11 ETS80036.1 - 3e-46 157.8 16.6 3.7e-46 157.5 16.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4131 PF13567.6 ETS80036.1 - 0.97 9.1 8.7 6 6.5 2.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Lactamase_B PF00753.27 ETS80037.1 - 7.3e-16 58.8 2.7 2.1e-15 57.2 2.7 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS80037.1 - 0.0015 18.1 0.1 0.0023 17.5 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pyr_redox_2 PF07992.14 ETS80038.1 - 3.3e-14 52.8 0.0 3.3e-10 39.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS80038.1 - 0.0013 18.7 0.1 0.0053 16.8 0.1 2.1 1 1 1 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 ETS80038.1 - 0.0042 16.7 1.3 0.014 15.0 1.0 1.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS80038.1 - 0.038 14.2 0.1 0.091 13.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ETS80038.1 - 0.059 12.4 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 ETS80038.1 - 0.083 11.7 0.4 0.12 11.2 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 ETS80038.1 - 0.22 10.7 0.0 1.6 7.9 0.0 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-rbx1 PF12678.7 ETS80039.1 - 1.7e-09 37.8 3.0 3.2e-09 36.9 3.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ETS80039.1 - 8.5e-09 35.6 3.6 1.8e-08 34.6 3.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ETS80039.1 - 6.7e-06 26.0 1.2 1.3e-05 25.1 1.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ETS80039.1 - 8.3e-06 25.7 1.4 2.5e-05 24.2 1.5 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ETS80039.1 - 4.9e-05 23.1 1.9 8.5e-05 22.3 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS80039.1 - 0.00021 21.0 4.5 0.0021 17.9 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ETS80039.1 - 0.00027 20.7 2.2 0.00069 19.4 2.3 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 ETS80039.1 - 0.0023 17.5 0.3 0.0052 16.4 0.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 ETS80039.1 - 0.0031 17.5 2.1 0.008 16.2 2.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 ETS80039.1 - 0.0032 17.3 2.5 0.0032 17.3 2.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ETS80039.1 - 0.13 12.0 1.3 1.8 8.4 1.3 2.3 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 ETS80039.1 - 0.25 11.5 0.8 0.51 10.5 0.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 ETS80039.1 - 1.7 8.5 3.2 0.96 9.3 0.7 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain CMD PF02627.20 ETS80040.1 - 0.00038 20.5 0.1 0.0037 17.3 0.0 2.3 2 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family zf-C2H2 PF00096.26 ETS80041.1 - 2.1e-05 24.7 18.2 0.21 12.1 1.2 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type Secretin_N_2 PF07655.13 ETS80041.1 - 0.0069 16.9 1.9 0.16 12.5 0.0 2.7 2 0 0 2 2 2 1 Secretin N-terminal domain DUF2415 PF10313.9 ETS80041.1 - 0.063 13.2 0.0 2 8.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) zf-met PF12874.7 ETS80041.1 - 0.26 11.7 3.8 1.3 9.5 0.6 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-TAZ PF02135.16 ETS80041.1 - 0.31 11.5 4.2 0.28 11.7 1.6 2.0 2 0 0 2 2 2 0 TAZ zinc finger zf-C2H2_4 PF13894.6 ETS80041.1 - 0.39 11.7 20.1 0.43 11.5 0.9 4.8 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ETS80041.1 - 0.54 10.6 5.3 3.5 8.0 0.5 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Methyltransf_16 PF10294.9 ETS80042.1 - 2.6e-09 37.1 0.0 4.5e-09 36.3 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 ETS80042.1 - 0.17 11.3 0.1 0.26 10.6 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Glyco_transf_8 PF01501.20 ETS80043.1 - 1.3e-22 80.6 0.1 1.8e-21 76.9 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 ETS80043.1 - 0.0039 16.6 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Cation_efflux PF01545.21 ETS80044.1 - 4.8e-16 59.1 8.7 6.2e-16 58.7 8.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ETS80044.1 - 1.1e-10 41.5 0.5 2.4e-10 40.4 0.5 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter EspB PF05802.11 ETS80044.1 - 0.0018 18.3 0.0 0.012 15.7 0.0 2.0 1 1 1 2 2 2 1 Enterobacterial EspB protein Glyco_hydro_47 PF01532.20 ETS80045.1 - 2.1e-169 564.3 0.0 2.4e-169 564.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 EF-hand_1 PF00036.32 ETS80046.1 - 1.1e-41 137.3 12.9 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ETS80046.1 - 3.5e-36 123.5 5.8 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 ETS80046.1 - 6.8e-35 118.7 11.4 2.3e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 ETS80046.1 - 2.1e-30 102.0 9.5 1.9e-09 36.7 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 ETS80046.1 - 6.5e-26 88.6 10.6 2.6e-06 26.7 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 ETS80046.1 - 1.5e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 ETS80046.1 - 3.4e-09 36.6 1.9 0.00075 19.4 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ETS80046.1 - 5.6e-09 36.3 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 ETS80046.1 - 9.9e-07 28.7 0.0 0.0077 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 ETS80046.1 - 5.8e-06 26.3 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 ETS80046.1 - 9.1e-05 23.3 0.2 0.0022 18.8 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 ETS80046.1 - 0.00012 22.0 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 ETS80046.1 - 0.00045 20.2 1.8 0.44 10.5 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 ETS80046.1 - 0.00062 20.1 0.8 0.66 10.3 0.1 2.7 2 1 1 3 3 3 2 RNA polymerase Rpb4 DUF3349 PF11829.8 ETS80046.1 - 0.0014 19.3 0.4 3.7 8.4 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 ETS80046.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 ETS80046.1 - 0.006 15.2 0.0 0.0062 15.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 ETS80046.1 - 0.0091 15.9 0.9 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 ETS80046.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 ETS80046.1 - 0.023 14.9 0.0 0.18 12.1 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 ETS80046.1 - 0.036 14.5 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RuvA_C PF07499.13 ETS80046.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain MotA_activ PF09114.10 ETS80046.1 - 0.061 13.4 0.3 1.2 9.3 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 ETS80046.1 - 0.066 12.4 0.1 1.1 8.4 0.1 2.1 1 1 1 2 2 2 0 Cache domain DUF5132 PF17195.4 ETS80046.1 - 0.15 12.2 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) RloB PF13707.6 ETS80046.1 - 0.16 12.2 1.1 0.76 9.9 0.2 2.0 1 1 1 2 2 2 0 RloB-like protein SNARE PF05739.19 ETS80047.1 - 4.8e-16 58.5 0.9 9.6e-16 57.5 0.9 1.5 1 0 0 1 1 1 1 SNARE domain MCPsignal PF00015.21 ETS80047.1 - 0.0018 18.1 6.3 0.14 12.0 0.3 2.8 3 0 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin PF00804.25 ETS80047.1 - 0.0027 17.4 9.8 0.017 14.8 0.3 2.1 2 0 0 2 2 2 2 Syntaxin GCP_C_terminal PF04130.13 ETS80047.1 - 0.015 14.8 1.2 0.11 12.0 0.1 2.1 2 0 0 2 2 2 0 Gamma tubulin complex component C-terminal DNA_repr_REX1B PF14966.6 ETS80047.1 - 0.2 12.4 3.9 0.34 11.6 0.9 2.7 2 1 1 3 3 3 0 DNA repair REX1-B SlyX PF04102.12 ETS80047.1 - 0.29 11.8 9.7 1.3 9.7 0.3 3.7 2 2 2 4 4 4 0 SlyX ATG16 PF08614.11 ETS80047.1 - 0.95 9.7 8.8 6.4 6.9 1.7 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) MFS_1 PF07690.16 ETS80050.1 - 1e-30 106.9 18.8 1e-30 106.9 18.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5337 PF17272.2 ETS80050.1 - 0.071 13.0 0.3 0.071 13.0 0.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Arylsulfotran_2 PF14269.6 ETS80051.1 - 1.4e-65 221.6 4.4 2.4e-65 220.9 4.4 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 ETS80051.1 - 1.5e-18 66.9 0.7 1.5e-17 63.6 0.7 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) MFS_1 PF07690.16 ETS80052.1 - 6.7e-09 35.1 36.2 1.1e-08 34.4 15.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 ETS80053.1 - 8.8e-12 44.6 0.4 3.1e-11 42.8 0.2 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS80053.1 - 8.6e-07 29.0 13.2 1.7e-06 28.0 13.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2018 PF09442.10 ETS80054.1 - 0.061 14.3 0.0 0.099 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) PYRIN PF02758.16 ETS80054.1 - 0.16 12.2 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain Dioxygenase_C PF00775.21 ETS80055.1 - 2.1e-07 30.5 0.1 3.3e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase DUF5495 PF17599.2 ETS80055.1 - 0.12 12.6 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5495) Tyrosinase PF00264.20 ETS80056.1 - 2e-36 126.3 8.9 9e-36 124.2 8.9 1.9 1 1 0 1 1 1 1 Common central domain of tyrosinase BOFC_N PF08977.10 ETS80058.1 - 0.028 14.4 1.0 0.045 13.7 1.0 1.3 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal Hydantoinase_B PF02538.14 ETS80060.1 - 7.3e-201 668.0 0.7 9.5e-201 667.7 0.7 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 ETS80060.1 - 3e-98 328.7 0.3 2.8e-97 325.5 0.1 2.5 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ETS80060.1 - 1.5e-57 194.1 0.1 9.1e-56 188.4 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.16 ETS80061.1 - 5.4e-33 114.4 28.0 8.1e-33 113.8 28.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily GATase PF00117.28 ETS80062.1 - 0.0005 19.9 0.0 0.0021 17.8 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Aminotran_1_2 PF00155.21 ETS80063.1 - 8.4e-19 67.9 0.0 1.9e-18 66.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ETS80063.1 - 0.0013 17.6 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase ICL PF00463.21 ETS80064.1 - 7.3e-121 404.2 0.7 9e-121 403.9 0.7 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 ETS80064.1 - 9.9e-07 28.4 0.0 2.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Fungal_trans PF04082.18 ETS80065.1 - 2.9e-12 46.2 3.5 4.7e-12 45.5 3.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS80065.1 - 6e-07 29.5 12.8 1.2e-06 28.6 12.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 ETS80066.1 - 6.7e-59 200.1 0.0 8.8e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS80066.1 - 6.9e-08 32.6 0.1 2.9e-07 30.6 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS80066.1 - 0.00021 22.0 0.1 0.00028 21.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 ETS80066.1 - 0.0073 15.2 0.4 2.6 6.8 0.0 2.2 2 0 0 2 2 2 2 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 ETS80066.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ETS80067.1 - 1.1e-22 81.0 0.0 2e-21 76.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS80067.1 - 1.6e-11 45.2 1.7 2.3e-11 44.8 1.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS80067.1 - 1.8e-09 37.2 0.0 3.7e-09 36.2 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Acyl_transf_2 PF02273.15 ETS80067.1 - 0.019 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase Abhydrolase_4 PF08386.10 ETS80067.1 - 0.11 12.6 0.0 0.99 9.5 0.0 2.3 3 0 0 3 3 3 0 TAP-like protein DFP PF04127.15 ETS80067.1 - 0.2 11.5 0.0 0.67 9.7 0.0 1.7 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein adh_short PF00106.25 ETS80068.1 - 1e-33 116.5 0.0 1.4e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS80068.1 - 1.9e-27 96.3 0.0 2.7e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS80068.1 - 0.00016 21.6 0.0 0.0014 18.6 0.1 2.2 2 1 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.8 ETS80068.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HgmA PF04209.13 ETS80069.1 - 1e-167 558.2 0.1 1.2e-167 558.0 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase COesterase PF00135.28 ETS80070.1 - 5.8e-49 167.3 0.0 6.6e-41 140.7 0.0 2.0 1 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS80070.1 - 0.011 15.6 0.6 0.021 14.7 0.6 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF4357 PF14267.6 ETS80070.1 - 0.13 12.3 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) FAD_binding_4 PF01565.23 ETS80071.1 - 1.2e-17 64.0 0.1 1.7e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.22 ETS80072.1 - 3.6e-69 233.7 0.0 6.1e-69 232.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Seadorna_VP6 PF07407.11 ETS80072.1 - 0.0073 15.3 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP6 protein Dioxygenase_C PF00775.21 ETS80073.1 - 1.1e-09 38.0 0.1 2.2e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Dioxygenase p450 PF00067.22 ETS80074.1 - 1.3e-71 241.7 0.0 1.7e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.6 ETS80075.1 - 1.9e-12 47.5 0.0 1e-09 38.6 0.0 2.3 2 0 0 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 ETS80075.1 - 0.00023 20.7 0.0 0.00037 20.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS80075.1 - 0.025 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_11 PF14833.6 ETS80076.1 - 1.5e-22 80.1 0.1 2.6e-22 79.3 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 ETS80076.1 - 3.4e-19 69.6 0.0 5.5e-19 68.9 0.0 1.4 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_2 PF03446.15 ETS80077.1 - 5.4e-37 127.4 0.0 7.1e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ETS80077.1 - 1.9e-21 76.5 0.0 3e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 ETS80077.1 - 2.7e-05 23.3 0.0 3.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family 2-Hacid_dh_C PF02826.19 ETS80077.1 - 0.002 17.5 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ETS80077.1 - 0.0046 17.5 0.0 0.0081 16.7 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 ETS80077.1 - 0.043 14.1 0.0 0.065 13.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 ETS80077.1 - 0.12 12.0 0.0 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain p450 PF00067.22 ETS80078.1 - 7.5e-59 199.7 0.0 9.8e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 ETS80079.1 - 4.6e-50 170.8 0.0 6.2e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS80079.1 - 2.4e-07 30.6 0.1 0.016 14.8 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS80079.1 - 1.4e-05 25.2 0.0 3.4e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS80079.1 - 0.0004 19.7 0.0 0.00079 18.7 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS80079.1 - 0.00095 18.0 0.0 0.0042 15.8 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 ETS80079.1 - 0.0012 18.2 0.0 0.005 16.2 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 ETS80079.1 - 0.0038 16.5 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS80079.1 - 0.0075 15.4 0.0 0.037 13.1 0.0 1.9 1 1 1 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 ETS80079.1 - 0.011 15.7 0.1 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 ETS80079.1 - 0.015 14.6 0.1 0.061 12.7 0.1 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS80079.1 - 0.026 15.1 0.0 2.6 8.6 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS80079.1 - 0.1 11.6 0.0 0.22 10.6 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein SE PF08491.10 ETS80079.1 - 0.15 11.1 0.0 7 5.6 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase Lactamase_B PF00753.27 ETS80080.1 - 4.6e-08 33.3 0.0 8.3e-07 29.2 0.0 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS80080.1 - 0.00011 21.8 0.0 0.00027 20.5 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ETS80080.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DUF4336 PF14234.6 ETS80080.1 - 0.11 11.7 0.0 1.2 8.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4336) Lactamase_B PF00753.27 ETS80081.1 - 3.1e-05 24.1 5.4 0.00018 21.6 5.4 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS80081.1 - 0.00064 19.3 0.1 0.0013 18.3 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CMD PF02627.20 ETS80082.1 - 1.2e-20 73.3 0.2 2e-20 72.6 0.1 1.5 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family DUF2827 PF10933.8 ETS80082.1 - 0.16 10.6 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) Fungal_trans PF04082.18 ETS80083.1 - 7e-12 44.9 2.0 1.2e-11 44.1 2.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 ETS80083.1 - 4.6e-08 33.1 15.0 0.0015 18.9 2.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS80083.1 - 0.00011 22.8 13.3 0.057 14.3 2.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger PyrI_C PF02748.15 ETS80083.1 - 0.0087 16.0 4.2 0.48 10.4 0.2 2.5 2 0 0 2 2 2 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-H2C2_2 PF13465.6 ETS80083.1 - 0.011 16.2 19.5 0.019 15.3 8.0 3.0 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ETS80083.1 - 0.058 13.7 9.8 0.56 10.6 4.6 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 ETS80083.1 - 0.22 11.6 7.9 2.7 8.1 1.8 2.5 1 1 1 2 2 2 0 BED zinc finger LIM PF00412.22 ETS80083.1 - 0.81 10.0 5.9 1.9 8.8 5.9 1.6 1 0 0 1 1 1 0 LIM domain p450 PF00067.22 ETS80084.1 - 9.5e-73 245.5 0.0 1.1e-72 245.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UBA2_C PF16195.5 ETS80085.1 - 0.81 10.4 14.7 0.034 14.8 7.3 2.3 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus DUF3584 PF12128.8 ETS80086.1 - 0.99 6.8 15.3 1.6 6.1 15.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_18 PF13238.6 ETS80087.1 - 9.2e-10 39.2 0.0 1.3e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ETS80087.1 - 1.1e-05 25.6 0.1 1.6e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 ETS80087.1 - 0.00013 21.3 0.1 0.00021 20.7 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 ETS80087.1 - 0.0012 19.3 0.1 0.0023 18.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 ETS80087.1 - 0.0037 16.8 0.0 0.0047 16.4 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 APS_kinase PF01583.20 ETS80087.1 - 0.0043 17.0 0.0 0.0073 16.2 0.0 1.4 1 1 0 1 1 1 1 Adenylylsulphate kinase Thymidylate_kin PF02223.17 ETS80087.1 - 0.019 14.6 1.2 0.12 12.0 0.1 2.2 2 1 0 2 2 2 0 Thymidylate kinase TTR-52 PF01060.23 ETS80087.1 - 0.098 13.4 0.0 0.2 12.4 0.0 1.6 1 0 0 1 1 1 0 Transthyretin-like family CxC2 PF18803.1 ETS80087.1 - 0.12 12.5 0.1 0.26 11.5 0.0 1.5 2 0 0 2 2 2 0 CxC2 like cysteine cluster associated with KDZ transposases MFS_1 PF07690.16 ETS80088.1 - 7.7e-12 44.8 22.9 6.4e-10 38.5 13.0 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily PD40 PF07676.12 ETS80089.1 - 1.6e-40 136.3 23.6 2.7e-07 30.3 0.2 9.1 9 0 0 9 9 9 7 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 ETS80089.1 - 3.1e-11 42.6 0.1 0.022 13.5 0.0 5.2 5 0 0 5 5 5 4 Dipeptidyl peptidase IV (DPP IV) N-terminal region Spike_torovirin PF17072.5 ETS80089.1 - 0.037 11.2 0.5 0.051 10.7 0.5 1.1 1 0 0 1 1 1 0 Torovirinae spike glycoprotein DUF5050 PF16472.5 ETS80089.1 - 0.057 12.7 0.3 8.5 5.5 0.0 4.1 4 1 0 4 4 4 0 Domain of unknown function (DUF5050) DUF3748 PF12566.8 ETS80089.1 - 0.15 12.0 0.1 32 4.5 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3748) WD40 PF00400.32 ETS80089.1 - 0.85 10.6 5.1 68 4.6 0.1 5.5 6 1 1 7 7 7 0 WD domain, G-beta repeat LysM PF01476.20 ETS80090.1 - 1.2e-08 34.8 0.1 0.0073 16.4 0.0 3.8 4 0 0 4 4 4 2 LysM domain PrmA PF06325.13 ETS80090.1 - 0.31 10.4 0.9 0.4 10.0 0.9 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PPR_2 PF13041.6 ETS80092.1 - 0.1 12.8 0.0 16 5.8 0.0 3.7 4 0 0 4 4 4 0 PPR repeat family COX7a PF02238.15 ETS80093.1 - 3.3e-17 62.6 1.4 3.8e-17 62.4 1.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Clathrin_lg_ch PF01086.17 ETS80094.1 - 3.8e-79 266.0 5.8 4.2e-79 265.8 5.8 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF5630 PF18632.1 ETS80094.1 - 0.15 11.3 2.8 0.23 10.7 2.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5630) DUF4407 PF14362.6 ETS80094.1 - 1.5 8.1 6.8 1.7 7.9 3.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CTD_bind PF04818.13 ETS80095.1 - 7.4e-19 68.3 0.5 2.9e-18 66.5 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CENP-Q PF13094.6 ETS80095.1 - 0.057 13.6 2.3 0.14 12.4 2.2 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CREPT PF16566.5 ETS80095.1 - 0.064 13.4 1.3 0.16 12.1 0.0 2.3 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour CTK3 PF12243.8 ETS80095.1 - 0.1 12.6 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 NMO PF03060.15 ETS80097.1 - 8.1e-53 179.9 1.2 1.2e-52 179.4 1.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ETS80097.1 - 3.8e-09 36.0 3.6 1.5e-07 30.8 3.1 2.7 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ETS80097.1 - 0.0051 15.9 5.4 0.0051 15.9 5.4 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase SAC3_GANP PF03399.16 ETS80099.1 - 5e-76 255.9 0.0 5e-76 255.9 0.0 1.4 2 0 0 2 2 2 1 SAC3/GANP family zf-C2H2 PF00096.26 ETS80100.1 - 1.3e-10 41.1 14.5 0.061 13.8 0.3 6.1 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS80100.1 - 2.1e-08 34.3 11.5 4.6 8.3 0.0 6.0 6 0 0 6 6 6 4 C2H2-type zinc finger zf-met PF12874.7 ETS80100.1 - 6.2e-05 23.2 13.1 0.14 12.6 0.2 5.3 6 0 0 6 6 5 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 ETS80100.1 - 0.00046 20.4 13.3 0.019 15.3 1.3 3.1 3 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 ETS80100.1 - 0.00087 19.5 8.1 0.21 11.9 0.0 5.0 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ETS80100.1 - 0.0014 18.8 9.7 0.33 11.3 0.6 3.5 2 1 1 3 3 3 3 C2H2-type zinc ribbon zf-C2H2_9 PF16293.5 ETS80100.1 - 0.0035 17.2 5.0 15 5.5 0.0 5.2 2 2 3 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 ETS80100.1 - 0.0075 16.6 13.4 1.6 9.1 0.5 4.3 2 2 2 4 4 4 3 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 ETS80100.1 - 0.022 15.4 9.9 6.6 7.4 0.1 4.9 2 2 3 5 5 5 0 FOXP coiled-coil domain CK_II_beta PF01214.18 ETS80100.1 - 0.079 12.8 0.5 11 5.7 0.0 2.2 2 0 0 2 2 2 0 Casein kinase II regulatory subunit zf-H2C2_2 PF13465.6 ETS80100.1 - 0.17 12.4 0.1 0.17 12.4 0.1 4.2 5 0 0 5 5 3 0 Zinc-finger double domain zinc_ribbon_4 PF13717.6 ETS80100.1 - 0.53 10.2 3.9 34 4.5 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-Mss51 PF13824.6 ETS80100.1 - 2.9 8.1 9.9 5.3 7.2 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 IBR PF01485.21 ETS80100.1 - 4.5 7.6 12.4 7 7.0 5.8 3.0 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain IF4E PF01652.18 ETS80101.1 - 1.4e-48 164.7 0.0 2.2e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CAF1A PF12253.8 ETS80102.1 - 1.8e-21 76.0 1.6 1.8e-21 76.0 1.6 3.0 2 1 0 2 2 1 1 Chromatin assembly factor 1 subunit A Borrelia_P83 PF05262.11 ETS80102.1 - 0.0026 16.3 16.9 0.0038 15.8 16.9 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein FAM60A PF15396.6 ETS80102.1 - 0.36 10.8 6.9 0.9 9.5 6.9 1.8 1 0 0 1 1 1 0 Protein Family FAM60A DUF3292 PF11696.8 ETS80102.1 - 0.53 8.6 14.2 1 7.7 14.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Zip PF02535.22 ETS80102.1 - 0.84 8.8 2.2 1.2 8.3 2.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Nop53 PF07767.11 ETS80102.1 - 0.88 8.9 28.3 0.041 13.3 17.6 2.4 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Pox_Ag35 PF03286.14 ETS80102.1 - 1.8 8.3 21.6 12 5.6 16.1 2.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SAPS PF04499.15 ETS80102.1 - 2.2 7.0 8.3 3.7 6.2 8.3 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPR3 PF03666.13 ETS80102.1 - 2.7 6.7 9.8 4.4 6.0 9.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tim54 PF11711.8 ETS80102.1 - 3.7 6.2 13.7 7 5.3 13.7 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MCM_bind PF09739.9 ETS80102.1 - 8.9 4.6 10.5 14 3.9 10.5 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CCSAP PF15748.5 ETS80102.1 - 10 6.2 24.1 4.5 7.4 19.0 2.5 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated HET PF06985.11 ETS80103.1 - 1.4e-31 109.8 0.3 2.3e-31 109.1 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3433 PF11915.8 ETS80104.1 - 1.2e-25 89.8 26.4 5e-21 75.0 4.2 4.0 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Claudin_2 PF13903.6 ETS80104.1 - 0.031 14.1 0.0 7.4 6.3 0.0 3.2 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF2235 PF09994.9 ETS80105.1 - 3.9e-42 144.6 0.1 7.1e-42 143.7 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MMR_HSR1 PF01926.23 ETS80105.1 - 4.2e-05 23.6 0.0 8.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 ETS80105.1 - 0.0027 17.9 0.1 0.074 13.3 0.1 2.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 ETS80105.1 - 0.0028 17.4 0.0 0.011 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ETS80105.1 - 0.0088 16.0 0.0 0.041 13.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 ETS80105.1 - 0.0095 16.5 0.0 0.03 14.8 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 ETS80105.1 - 0.024 14.4 0.0 0.074 12.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ETS80105.1 - 0.026 15.0 0.3 0.11 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ETS80105.1 - 0.057 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Peptidase_M48_N PF16491.5 ETS80106.1 - 1e-66 224.3 8.8 1e-66 224.3 8.8 1.8 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 ETS80106.1 - 1.2e-47 162.3 0.0 2.2e-47 161.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 ETS80106.1 - 0.00015 21.1 0.2 0.00037 19.8 0.2 1.7 1 1 0 1 1 1 1 BlaR1 peptidase M56 SprT-like PF10263.9 ETS80106.1 - 0.078 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 SprT-like family DUF4538 PF15061.6 ETS80106.1 - 0.22 11.3 3.1 0.82 9.5 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) OB_NTP_bind PF07717.16 ETS80107.1 - 5.1e-17 62.0 0.0 3.3e-16 59.4 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 ETS80107.1 - 5.8e-17 61.9 0.6 5.4e-16 58.8 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ETS80107.1 - 1.7e-16 60.5 0.1 6.3e-16 58.7 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ETS80107.1 - 6.4e-11 42.3 0.2 1.8e-10 40.9 0.2 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase RWD PF05773.22 ETS80107.1 - 5.5e-07 29.9 0.5 1.6e-06 28.4 0.1 2.0 2 0 0 2 2 2 1 RWD domain ResIII PF04851.15 ETS80107.1 - 9.1e-05 22.5 0.0 0.00033 20.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ETS80107.1 - 0.0042 17.4 1.1 0.024 14.9 1.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ETS80107.1 - 0.0078 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase PF06745.13 ETS80107.1 - 0.0087 15.4 0.0 0.025 14.0 0.0 1.7 1 0 0 1 1 1 1 KaiC IstB_IS21 PF01695.17 ETS80107.1 - 0.035 13.8 0.2 0.67 9.7 0.2 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 ETS80107.1 - 0.057 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 ETS80107.1 - 0.062 12.4 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 ETS80107.1 - 0.084 13.4 0.0 0.28 11.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter DND1_DSRM PF14709.7 ETS80107.1 - 0.16 12.2 0.1 0.48 10.7 0.1 1.9 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 IHABP4_N PF16174.5 ETS80107.1 - 0.71 10.5 11.0 0.094 13.3 0.4 2.8 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal AAA_23 PF13476.6 ETS80107.1 - 1.5 9.3 5.6 0.86 10.1 0.9 2.6 2 1 0 2 2 2 0 AAA domain zf-C2HE PF16278.5 ETS80108.1 - 6.6e-19 68.1 0.0 1.5e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 ETS80108.1 - 4.2e-16 59.4 2.7 4.1e-15 56.2 2.7 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 ETS80108.1 - 7.9e-15 55.4 0.1 1.8e-14 54.2 0.1 1.6 1 1 0 1 1 1 1 HIT domain Phage_TAC_5 PF08890.11 ETS80108.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Phage XkdN-like tail assembly chaperone protein, TAC AT_hook PF02178.19 ETS80109.1 - 0.00063 19.3 50.9 0.03 14.2 4.3 6.1 6 1 1 7 7 7 4 AT hook motif TFIIA PF03153.13 ETS80109.1 - 0.18 11.8 5.5 0.25 11.3 5.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ORC6 PF05460.13 ETS80109.1 - 1.3 8.2 5.8 1.8 7.8 5.8 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DIOX_N PF14226.6 ETS80110.1 - 6.8e-18 65.5 0.1 1.5e-17 64.5 0.1 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS80110.1 - 8.7e-16 58.3 0.0 1.7e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Kinesin PF00225.23 ETS80111.1 - 1.1e-113 379.5 0.0 1.6e-113 379.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ETS80111.1 - 6.6e-25 87.8 0.0 1.6e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Spc7 PF08317.11 ETS80111.1 - 0.031 13.1 7.7 0.054 12.4 7.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2018 PF09442.10 ETS80111.1 - 0.52 11.3 4.7 2.4 9.2 1.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) DUF87 PF01935.17 ETS80111.1 - 0.81 9.7 0.0 0.81 9.7 0.0 3.3 3 1 0 3 3 3 0 Helicase HerA, central domain DUF5094 PF17015.5 ETS80111.1 - 9.2 6.3 9.5 1.9 8.6 4.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) Cupin_8 PF13621.6 ETS80112.1 - 1.8e-68 231.0 0.3 2e-68 230.8 0.3 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 ETS80112.1 - 7.3e-07 28.9 0.0 0.00037 20.1 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 ETS80112.1 - 0.00044 20.6 0.2 0.017 15.5 0.0 3.0 3 1 0 3 3 3 1 JmjC domain, hydroxylase Sterol-sensing PF12349.8 ETS80113.1 - 2.6e-35 121.5 8.3 5.3e-35 120.5 8.3 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 ETS80113.1 - 3.5e-08 32.0 7.0 5.2e-08 31.5 7.0 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 ETS80113.1 - 0.00018 22.2 0.2 0.0024 18.7 0.1 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat CaM_bdg_C0 PF10562.9 ETS80113.1 - 4.5 7.4 5.1 3.6 7.7 3.3 1.7 2 0 0 2 2 2 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit NqrM PF04400.13 ETS80114.1 - 0.35 10.6 4.7 1.5 8.6 2.2 2.3 2 0 0 2 2 2 0 (Na+)-NQR maturation NqrM 14-3-3 PF00244.20 ETS80115.1 - 6e-07 29.2 0.1 1.6e-06 27.8 0.0 1.7 2 1 1 3 3 3 1 14-3-3 protein SpoIIID PF12116.8 ETS80116.1 - 0.091 12.9 0.5 0.17 12.0 0.5 1.4 1 0 0 1 1 1 0 Stage III sporulation protein D AP3D1 PF06375.11 ETS80116.1 - 0.13 12.5 6.4 0.26 11.5 6.4 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 FMN_dh PF01070.18 ETS80117.1 - 1.5e-114 382.7 0.0 1.8e-114 382.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ETS80117.1 - 4.6e-18 65.1 0.0 1e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 ETS80117.1 - 1.5e-05 24.1 1.8 0.00015 20.9 1.2 2.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ETS80117.1 - 0.00024 20.4 0.6 0.0014 17.8 0.0 2.3 2 1 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 ETS80117.1 - 0.00028 20.4 0.1 0.00044 19.7 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 ETS80117.1 - 0.001 18.5 0.1 0.046 13.0 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG DUF5078 PF16877.5 ETS80117.1 - 0.018 15.5 0.1 0.037 14.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5078) DHO_dh PF01180.21 ETS80117.1 - 0.022 14.0 0.5 4.5 6.4 0.0 2.4 2 1 0 2 2 2 0 Dihydroorotate dehydrogenase Peptidase_M19 PF01244.21 ETS80117.1 - 0.038 13.1 0.0 0.22 10.6 0.0 2.1 2 1 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) SIS PF01380.22 ETS80117.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 SIS domain DUF4202 PF13875.6 ETS80118.1 - 1.9e-77 259.4 0.2 2.1e-77 259.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) MGC-24 PF05283.11 ETS80119.1 - 0.015 15.7 3.0 0.015 15.7 3.0 2.4 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin EphA2_TM PF14575.6 ETS80119.1 - 0.042 14.7 0.0 0.14 13.1 0.0 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gly-zipper_Omp PF13488.6 ETS80119.1 - 0.29 11.1 12.6 0.7 9.9 12.6 1.6 1 0 0 1 1 1 0 Glycine zipper Phage_HK97_TLTM PF06120.11 ETS80119.1 - 0.52 9.4 0.9 0.78 8.9 0.9 1.1 1 0 0 1 1 1 0 Tail length tape measure protein Miga PF10265.9 ETS80119.1 - 7.1 5.5 5.3 11 4.9 5.3 1.2 1 0 0 1 1 1 0 Mitoguardin Med5 PF08689.10 ETS80121.1 - 7.6e-101 338.6 0.0 3.1e-100 336.6 0.0 2.0 1 1 0 1 1 1 1 Mediator complex subunit Med5 MOR2-PAG1_C PF14225.6 ETS80121.1 - 0.01 15.7 1.1 1.1 9.1 0.1 3.2 3 0 0 3 3 3 0 Cell morphogenesis C-terminal SSF PF00474.17 ETS80121.1 - 0.016 14.1 0.1 0.03 13.2 0.1 1.4 1 0 0 1 1 1 0 Sodium:solute symporter family p450 PF00067.22 ETS80122.1 - 3e-47 161.4 0.0 3.9e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3176 PF11374.8 ETS80123.1 - 1e-29 102.8 0.7 1e-29 102.8 0.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF2207 PF09972.9 ETS80123.1 - 0.13 11.0 0.0 1.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) GP41 PF00517.17 ETS80123.1 - 1.1 9.2 5.2 10 6.0 0.3 2.8 3 0 0 3 3 3 0 Retroviral envelope protein DUF2721 PF11026.8 ETS80123.1 - 1.5 8.7 7.9 0.55 10.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Mito_carr PF00153.27 ETS80124.1 - 1.8e-73 242.6 0.8 3.4e-26 91.0 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 ETS80124.1 - 8.5e-15 53.1 1.4 3.2e-06 26.3 0.1 5.9 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.6 ETS80124.1 - 1.4e-14 52.7 0.9 4e-06 26.3 0.1 6.1 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.6 ETS80124.1 - 1.5e-14 54.2 4.1 3.7e-07 30.5 0.4 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 ETS80124.1 - 1e-06 27.9 2.5 0.00026 20.4 0.2 3.6 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 ETS80124.1 - 4.8e-06 26.3 3.2 2.2 8.2 0.0 5.4 5 1 0 5 5 5 3 EF-hand domain pair EF-hand_9 PF14658.6 ETS80124.1 - 0.021 15.2 0.0 33 4.9 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain Cyclin_N PF00134.23 ETS80125.1 - 2.6e-44 150.0 0.3 7.5e-44 148.5 0.3 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ETS80125.1 - 4.6e-35 120.3 0.8 2.7e-34 117.8 0.2 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain Zn_clus PF00172.18 ETS80126.1 - 0.00047 20.2 12.3 0.00084 19.4 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 ETS80126.1 - 0.014 14.9 0.0 0.045 13.2 0.0 1.9 1 0 0 1 1 1 0 Histone chaperone domain CHZ GATase_4 PF13230.6 ETS80127.1 - 2.1e-16 59.7 0.0 5.3e-14 51.8 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 ETS80127.1 - 1.7e-08 34.7 0.0 2.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Aminotran_1_2 PF00155.21 ETS80128.1 - 5.6e-22 78.4 0.0 7.2e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ETS80128.1 - 5.5e-12 45.2 0.0 9e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 ETS80128.1 - 0.091 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase zf-C2H2_4 PF13894.6 ETS80129.1 - 0.0042 17.8 4.4 0.0042 17.8 4.4 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 ETS80129.1 - 0.051 14.3 0.5 0.56 10.9 0.3 2.5 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats BIR PF00653.21 ETS80129.1 - 0.23 12.2 0.1 0.23 12.2 0.1 2.9 2 1 1 3 3 3 0 Inhibitor of Apoptosis domain zf-met PF12874.7 ETS80129.1 - 0.93 10.0 6.2 1.9 9.0 0.1 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PQ-loop PF04193.14 ETS80131.1 - 7e-24 83.4 19.0 2.3e-13 49.7 2.6 2.6 3 0 0 3 3 3 2 PQ loop repeat MFS_1 PF07690.16 ETS80132.1 - 3.1e-37 128.3 25.1 4e-37 128.0 25.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 ETS80133.1 - 6.9e-07 29.3 1.2 1.1e-05 25.4 1.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS80133.1 - 0.00098 19.8 7.1 0.0015 19.2 7.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.8 ETS80133.1 - 0.2 11.2 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) SKG6 PF08693.10 ETS80134.1 - 0.86 9.1 2.5 2.2 7.7 2.5 1.7 1 1 0 1 1 1 0 Transmembrane alpha-helix domain RNA_pol_Rpc4 PF05132.14 ETS80136.1 - 1.8e-24 86.9 0.1 1.8e-24 86.9 0.1 3.9 3 2 0 3 3 3 1 RNA polymerase III RPC4 TAF4 PF05236.14 ETS80136.1 - 9.4 5.9 11.4 0.11 12.3 0.8 2.3 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family UreD PF01774.17 ETS80137.1 - 1.8e-74 250.3 0.0 2.2e-74 250.0 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.11 ETS80138.1 - 3.4e-33 113.9 0.2 1.6e-32 111.8 0.2 2.2 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.6 ETS80138.1 - 5.1e-07 30.0 2.4 0.0005 20.4 0.2 3.1 1 1 1 2 2 2 2 HEAT repeats Cnd1 PF12717.7 ETS80138.1 - 0.00029 20.9 0.0 0.033 14.2 0.0 3.4 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ETS80138.1 - 0.0019 18.3 1.2 21 5.7 0.1 5.1 5 0 0 5 5 5 2 HEAT repeat DUF3431 PF11913.8 ETS80139.1 - 1.6e-69 234.0 0.9 2.2e-69 233.5 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) POT1PC PF16686.5 ETS80140.1 - 1.4e-47 161.4 0.0 2.8e-47 160.5 0.0 1.5 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 ETS80140.1 - 2.2e-07 30.8 0.0 8.2e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.25 ETS80140.1 - 0.03 14.3 0.1 2.6 8.1 0.0 2.7 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain REPA_OB_2 PF16900.5 ETS80140.1 - 0.11 12.4 0.1 1.9 8.4 0.0 2.6 2 0 0 2 2 2 0 Replication protein A OB domain Rtf2 PF04641.12 ETS80140.1 - 5.9 6.2 9.1 2 7.7 3.3 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger Arm PF00514.23 ETS80141.1 - 1.1e-96 314.2 16.5 2.7e-13 49.4 0.2 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 ETS80141.1 - 4.4e-27 94.3 1.1 1.2e-26 93.0 1.1 1.8 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 ETS80141.1 - 2.2e-24 85.5 6.1 5.7e-09 36.3 0.1 6.4 6 0 0 6 6 6 4 HEAT-like repeat Arm_3 PF16186.5 ETS80141.1 - 6.2e-24 83.3 4.3 9.2e-24 82.8 3.2 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 ETS80141.1 - 4e-20 72.0 0.0 8e-09 35.8 0.0 5.3 1 1 2 5 5 5 4 HEAT repeats HEAT PF02985.22 ETS80141.1 - 3.9e-19 67.1 3.2 1.1e-05 25.2 0.0 7.4 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 ETS80141.1 - 1.3e-07 31.4 0.0 0.034 13.6 0.1 3.9 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.20 ETS80141.1 - 5e-05 22.1 0.0 0.011 14.3 0.0 2.8 1 1 2 3 3 3 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 ETS80141.1 - 0.00033 20.8 0.0 1.7 8.8 0.0 4.3 3 2 2 5 5 5 2 V-ATPase subunit H HEAT_PBS PF03130.16 ETS80141.1 - 0.00073 20.0 0.2 1.9 9.4 0.0 4.6 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 ETS80141.1 - 0.014 15.5 0.0 7.8 6.5 0.0 2.9 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 ETS80141.1 - 0.021 15.0 4.7 5.4 7.3 0.0 4.8 3 2 3 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 NopRA1 PF16201.5 ETS80141.1 - 0.062 12.9 0.0 9.7 5.7 0.0 3.6 2 2 3 5 5 5 0 Nucleolar pre-ribosomal-associated protein 1 Glycos_trans_3N PF02885.17 ETS80141.1 - 0.11 12.4 0.0 6.8 6.6 0.0 3.1 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain NUSAP PF16006.5 ETS80141.1 - 5.9 6.6 5.8 8.3 6.1 5.8 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein Cu_amine_oxid PF01179.20 ETS80142.1 - 1.8e-126 422.4 5.2 2.6e-126 421.9 5.2 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 ETS80142.1 - 1.4e-28 98.4 0.5 4.2e-28 96.9 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 ETS80142.1 - 1.3e-06 28.5 0.0 2.5e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain p450 PF00067.22 ETS80144.1 - 4.7e-48 164.1 0.0 6.4e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SKG6 PF08693.10 ETS80145.1 - 1.7e-07 30.5 0.3 1.7e-07 30.5 0.3 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 ETS80145.1 - 0.00081 19.5 1.3 0.0015 18.7 1.3 1.5 1 0 0 1 1 1 1 Podoplanin BatD PF13584.6 ETS80145.1 - 0.0046 15.8 0.0 0.0065 15.3 0.0 1.1 1 0 0 1 1 1 1 Oxygen tolerance DUF2207 PF09972.9 ETS80145.1 - 0.048 12.4 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Stevor PF17410.2 ETS80145.1 - 0.17 11.4 1.8 0.55 9.7 1.8 1.6 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame SPX PF03105.19 ETS80145.1 - 0.24 11.3 4.2 0.33 10.8 4.2 1.2 1 0 0 1 1 1 0 SPX domain TRAP_alpha PF03896.16 ETS80146.1 - 1.7e-12 47.1 0.0 1.9e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit AIF-MLS PF14962.6 ETS80146.1 - 0.04 13.9 0.1 0.079 12.9 0.0 1.5 2 0 0 2 2 2 0 Mitochondria Localisation Sequence FAA_hydrolase PF01557.18 ETS80147.1 - 4e-53 180.3 0.0 5.9e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 ETS80147.1 - 6.6e-12 45.6 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal PepX_C PF08530.10 ETS80148.1 - 1.8e-47 162.1 0.2 2.9e-47 161.5 0.2 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 ETS80148.1 - 7.7e-38 130.6 0.0 1.1e-37 130.1 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 ETS80148.1 - 0.034 13.4 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Aldedh PF00171.22 ETS80150.1 - 1e-09 37.5 0.8 0.00075 18.1 0.1 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family DUF4652 PF15525.6 ETS80150.1 - 0.025 14.4 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) LigB PF02900.18 ETS80151.1 - 1.7e-11 43.7 0.1 1.1e-10 41.1 0.1 1.9 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Abhydrolase_1 PF00561.20 ETS80152.1 - 3.1e-06 27.0 0.0 3.6e-05 23.5 0.0 2.4 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS80152.1 - 1.2e-05 26.0 0.7 2.5e-05 25.0 0.1 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ETS80152.1 - 0.00011 21.8 0.1 0.0073 15.8 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ETS80152.1 - 0.00023 20.5 0.0 0.00039 19.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 ETS80152.1 - 0.04 12.6 0.0 0.39 9.4 0.0 2.0 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 ETS80152.1 - 0.089 12.6 0.1 0.8 9.5 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_M20 PF01546.28 ETS80154.1 - 1.5e-25 90.1 0.1 2e-25 89.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ETS80154.1 - 1.5e-21 76.3 0.0 3.2e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ETS80154.1 - 2e-06 27.6 0.0 2.9e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M28 GMC_oxred_N PF00732.19 ETS80156.1 - 6e-48 163.7 0.0 9.5e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS80156.1 - 1.1e-35 123.3 0.0 1.9e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS80156.1 - 1.2e-06 27.9 0.9 0.0014 17.8 1.6 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 ETS80156.1 - 0.00081 18.7 2.5 0.54 9.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS80156.1 - 0.0011 18.3 1.9 0.0026 17.0 1.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS80156.1 - 0.0012 18.5 5.3 0.0067 16.0 2.4 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS80156.1 - 0.004 17.4 2.4 0.01 16.0 2.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ETS80156.1 - 0.1 11.8 1.8 0.17 11.1 0.5 1.8 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 ETS80156.1 - 0.1 11.6 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 ETS80156.1 - 0.4 9.7 4.7 0.61 9.1 1.3 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 ETS80156.1 - 1.1 8.5 3.6 2.5 7.3 2.4 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Glyco_transf_21 PF13506.6 ETS80157.1 - 5.7e-11 42.2 0.2 0.00033 20.2 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 ETS80157.1 - 4.2e-07 30.1 0.0 2.1e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ETS80157.1 - 0.0061 16.4 0.0 0.06 13.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 Anp1 PF03452.14 ETS80157.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Anp1 tRNA_int_endo PF01974.17 ETS80158.1 - 1.2e-17 63.8 0.0 2.5e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 ETS80158.1 - 2.9e-07 30.0 0.1 0.001 18.7 0.1 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain MFS_1 PF07690.16 ETS80159.1 - 5.4e-28 97.9 38.2 5.4e-28 97.9 38.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS80159.1 - 1.3e-08 34.2 14.8 3.9e-08 32.6 14.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Peptidase_S8 PF00082.22 ETS80160.1 - 3.7e-16 59.3 0.6 5.7e-16 58.6 0.6 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ETS80160.1 - 0.014 16.0 0.0 0.57 10.9 0.0 2.3 2 0 0 2 2 2 0 Peptidase inhibitor I9 HET PF06985.11 ETS80163.1 - 4e-18 66.2 2.1 4e-18 66.2 2.1 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Adap_comp_sub PF00928.21 ETS80164.1 - 3.2e-91 305.4 0.0 5.8e-91 304.5 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ETS80164.1 - 1.2e-08 35.0 0.2 1.9e-08 34.3 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Opi1 PF08618.10 ETS80165.1 - 1.8e-42 146.1 14.6 9.4e-33 114.1 1.5 4.0 2 1 2 4 4 4 3 Transcription factor Opi1 Lipase_GDSL_2 PF13472.6 ETS80166.1 - 2.2e-10 41.2 4.2 3.2e-10 40.7 4.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS80166.1 - 5.1e-05 23.3 0.4 7.8e-05 22.7 0.4 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ThrE PF06738.12 ETS80167.1 - 6.8e-51 173.0 11.5 3.5e-48 164.1 2.7 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ETS80167.1 - 6.5e-10 39.2 7.7 6.5e-10 39.2 7.7 2.6 2 1 0 2 2 2 1 Threonine/Serine exporter, ThrE DUF3736 PF12540.8 ETS80168.1 - 2.9 8.0 7.1 6.6 6.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3736) DnaJ PF00226.31 ETS80169.1 - 4.1e-22 78.1 2.7 8.6e-22 77.0 2.0 2.0 2 0 0 2 2 2 1 DnaJ domain Borrelia_P83 PF05262.11 ETS80169.1 - 0.61 8.5 14.0 0.15 10.5 9.6 1.9 2 0 0 2 2 2 0 Borrelia P83/100 protein DUF4407 PF14362.6 ETS80169.1 - 4.7 6.5 22.6 0.058 12.7 12.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 ETS80169.1 - 6.2 5.5 7.5 10 4.8 7.5 1.4 1 0 0 1 1 1 0 Presenilin Med9 PF07544.13 ETS80169.1 - 6.3 7.0 13.8 1 9.5 0.4 3.9 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Glyco_hydro_16 PF00722.21 ETS80171.1 - 7.9e-07 28.7 0.3 3.3e-06 26.7 0.2 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Polysacc_lyase PF14099.6 ETS80171.1 - 0.0052 16.6 0.2 0.0084 16.0 0.2 1.5 1 1 0 1 1 1 1 Polysaccharide lyase Laminin_G_3 PF13385.6 ETS80171.1 - 0.015 15.4 1.0 0.015 15.4 1.0 1.7 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Big_7 PF17957.1 ETS80171.1 - 0.02 15.7 0.2 0.066 14.0 0.2 1.9 1 0 0 1 1 1 0 Bacterial Ig domain DUF5644 PF18712.1 ETS80171.1 - 0.17 11.9 0.2 0.32 11.0 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5644) p450 PF00067.22 ETS80172.1 - 6.8e-57 193.2 0.0 9.3e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TP6A_N PF04406.14 ETS80173.1 - 3.4e-07 30.1 0.1 7.3e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase SQHop_cyclase_C PF13243.6 ETS80174.1 - 7.3e-47 160.0 1.6 1.5e-43 149.2 0.6 3.0 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 ETS80174.1 - 3.3e-39 134.7 3.5 4.6e-35 121.1 0.8 3.6 2 1 2 4 4 4 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 ETS80174.1 - 8.3e-27 92.6 3.8 9e-10 38.1 0.0 4.3 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 ETS80174.1 - 0.00016 20.8 0.0 0.0008 18.5 0.0 2.0 2 0 0 2 2 2 1 A-macroglobulin TED domain Pec_lyase PF09492.10 ETS80174.1 - 0.00038 19.9 1.1 0.6 9.4 0.0 4.1 2 1 1 4 4 4 2 Pectic acid lyase Chromadorea_ALT PF05535.12 ETS80174.1 - 0.022 14.9 0.0 0.061 13.5 0.0 1.8 1 0 0 1 1 1 0 Chromadorea ALT protein SGS PF05002.15 ETS80175.1 - 6.9e-27 93.4 8.0 7.7e-27 93.2 5.1 2.5 2 0 0 2 2 2 1 SGS domain CS PF04969.16 ETS80175.1 - 4.3e-12 46.9 1.4 9e-12 45.9 1.4 1.6 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 ETS80175.1 - 2.5e-06 27.2 2.4 0.23 11.7 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ETS80175.1 - 0.025 14.8 7.0 0.15 12.4 3.3 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 ETS80175.1 - 0.089 12.7 3.8 23 5.0 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 ETS80175.1 - 0.59 10.8 3.3 0.77 10.5 0.8 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.7 ETS80176.1 - 1.4e-20 73.7 4.5 1.9e-11 44.4 1.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS80176.1 - 3.5e-18 65.7 5.6 4.3e-11 43.1 0.4 2.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ETS80176.1 - 6e-12 45.4 6.5 3e-08 33.8 0.5 3.4 2 1 1 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 ETS80176.1 - 2.9e-11 42.6 2.3 6.8e-06 26.0 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 ETS80176.1 - 1.5e-10 41.1 2.1 1.6e-07 31.5 0.3 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) RHH_1 PF01402.21 ETS80176.1 - 0.086 12.8 1.5 0.086 12.8 1.5 2.1 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family DUF5585 PF17823.1 ETS80177.1 - 0.21 10.5 18.0 0.26 10.2 18.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Miga PF10265.9 ETS80177.1 - 4.4 6.2 9.3 5.7 5.8 9.3 1.1 1 0 0 1 1 1 0 Mitoguardin MFS_1 PF07690.16 ETS80178.1 - 6.3e-20 71.4 52.1 4e-19 68.8 49.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UCH PF00443.29 ETS80179.1 - 2.1e-67 227.3 0.0 3.4e-67 226.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ETS80179.1 - 1.1e-10 41.7 0.0 8.6e-06 25.6 0.0 3.3 2 1 1 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 ETS80179.1 - 1.4e-05 25.6 0.0 4.4e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 DUSP domain ubiquitin PF00240.23 ETS80179.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Aminotran_3 PF00202.21 ETS80180.1 - 2.4e-122 408.5 0.0 2.7e-122 408.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Glyco_hydro_35 PF01301.19 ETS80181.1 - 6.3e-80 269.1 6.4 1e-79 268.5 6.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 ETS80181.1 - 8.4e-56 187.5 4.0 4.7e-32 110.9 0.0 3.1 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 ETS80181.1 - 1.4e-49 168.4 4.7 1.4e-49 168.4 4.7 1.7 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 ETS80181.1 - 2.4e-23 81.5 0.0 5.3e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 ETS80181.1 - 1.3e-08 34.6 0.3 4.1e-05 23.1 0.2 3.7 2 1 1 3 3 3 2 Beta-galactosidase Cellulase PF00150.18 ETS80181.1 - 0.00018 21.1 0.5 0.0026 17.3 0.1 2.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Tmemb_185A PF10269.9 ETS80182.1 - 0.0072 16.0 4.3 0.011 15.5 4.3 1.2 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein SLAC1 PF03595.17 ETS80182.1 - 0.016 14.5 7.7 0.029 13.6 7.7 1.3 1 0 0 1 1 1 0 Voltage-dependent anion channel DUF3902 PF13042.6 ETS80182.1 - 0.13 11.8 4.2 0.2 11.2 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) TMEM173 PF15009.6 ETS80182.1 - 0.52 9.4 1.9 0.73 8.9 1.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 173 Trp_oprn_chp PF09534.10 ETS80182.1 - 0.57 9.9 8.5 0.92 9.3 8.5 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF420 PF04238.12 ETS80182.1 - 2.6 8.3 8.5 12 6.2 6.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF420) Pox_A14 PF05767.12 ETS80182.1 - 3.8 7.7 5.4 3.8 7.7 0.2 2.3 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 XPC-binding PF09280.11 ETS80183.1 - 3.5e-24 84.3 11.9 5.8e-24 83.6 11.9 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 ETS80183.1 - 8.3e-21 73.5 0.2 1.4e-20 72.8 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 ETS80183.1 - 1.2e-20 73.0 7.3 1.4e-12 47.2 0.6 2.6 2 1 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.8 ETS80183.1 - 3.2e-09 36.5 0.6 5.8e-09 35.7 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 ETS80183.1 - 0.046 13.8 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 ETS80183.1 - 0.051 13.9 0.1 0.093 13.1 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain UBA_3 PF09288.10 ETS80183.1 - 0.065 13.1 0.0 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain NMO PF03060.15 ETS80184.1 - 1.8e-58 198.5 0.6 2.4e-58 198.1 0.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ETS80184.1 - 5.7e-13 48.6 0.1 2.5e-12 46.5 0.1 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ETS80184.1 - 4.7e-06 25.9 0.3 7.8e-06 25.1 0.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ETS80184.1 - 7e-05 22.1 0.4 0.00014 21.2 0.4 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase NanE PF04131.14 ETS80184.1 - 0.0031 16.7 0.1 0.015 14.5 0.0 2.1 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase E3_UbLigase_EDD PF11547.8 ETS80184.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD PEP_hydrolase PF09370.10 ETS80184.1 - 0.11 11.8 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like DUF3932 PF13068.6 ETS80184.1 - 0.13 12.6 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) ECH_1 PF00378.20 ETS80185.1 - 2.4e-40 138.4 0.0 3.2e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ETS80185.1 - 1.2e-17 64.5 0.0 3.7e-17 62.8 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 ETS80185.1 - 0.029 14.3 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase family S49 AMP-binding PF00501.28 ETS80186.1 - 8.4e-82 275.0 0.0 1.1e-81 274.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS80186.1 - 1e-10 42.5 0.0 2.4e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.25 ETS80187.1 - 7.6e-14 51.7 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS80187.1 - 2.7e-07 30.1 0.0 5.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ETS80188.1 - 1e-54 185.7 0.0 1.4e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS80188.1 - 1.2e-29 103.5 0.0 1.8e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ETS80188.1 - 1.4e-05 24.1 0.2 3.2e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 ETS80188.1 - 3.9e-05 23.1 0.0 6.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ETS80188.1 - 0.023 14.7 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 ETS80188.1 - 0.041 13.5 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 ETS80188.1 - 0.073 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.22 ETS80189.1 - 3.4e-50 171.1 0.0 4.6e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 ETS80190.1 - 1e-22 81.1 0.0 2.2e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sulfotransfer_4 PF17784.1 ETS80192.1 - 7.4e-56 189.4 0.1 8.6e-56 189.1 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ETS80192.1 - 0.027 14.8 0.1 0.046 14.1 0.0 1.5 1 1 1 2 2 2 0 Sulfotransferase family GAS2 PF02187.17 ETS80192.1 - 0.093 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain Amastin PF07344.11 ETS80193.1 - 2 8.2 10.2 0.074 12.9 1.2 2.2 1 1 1 2 2 2 0 Amastin surface glycoprotein HKR_ArcB_TM PF18415.1 ETS80193.1 - 8.3 7.3 9.0 0.6 10.9 2.9 2.1 2 0 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain Sulfotransfer_4 PF17784.1 ETS80194.1 - 1.7e-49 168.5 0.0 2e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ETS80194.1 - 0.01 16.3 0.0 0.019 15.4 0.0 1.5 1 1 0 1 1 1 0 Sulfotransferase family UPF0220 PF05255.11 ETS80196.1 - 1.1e-67 226.7 3.1 1.2e-67 226.6 3.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF5337 PF17272.2 ETS80196.1 - 1.4 8.8 5.2 0.47 10.3 1.1 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF5337) SMI1_KNR4 PF09346.10 ETS80197.1 - 6.7e-30 104.2 0.0 1.1e-29 103.5 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) RAP1 PF07218.11 ETS80197.1 - 0.17 10.2 1.2 0.36 9.1 1.2 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sec8_exocyst PF04048.14 ETS80198.1 - 6.5e-48 162.2 0.1 1.8e-47 160.8 0.0 1.8 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 ETS80198.1 - 4.6e-09 36.0 0.4 8.4e-09 35.1 0.4 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 ETS80198.1 - 0.06 11.9 1.3 0.13 10.8 0.2 1.9 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 YcbB PF08664.10 ETS80198.1 - 0.11 12.6 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 YcbB domain DUF1657 PF07870.11 ETS80198.1 - 0.16 11.9 0.3 0.61 10.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) Swi5 PF07061.11 ETS80198.1 - 0.63 10.2 2.2 1.1 9.5 0.2 2.4 2 0 0 2 2 2 0 Swi5 His_Phos_2 PF00328.22 ETS80199.1 - 5.4e-25 88.6 0.0 1.1e-24 87.5 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Abhydrolase_2 PF02230.16 ETS80200.1 - 2.8e-12 46.9 0.0 1.2e-10 41.6 0.0 2.1 1 1 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 ETS80200.1 - 0.017 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Porin_3 PF01459.22 ETS80201.1 - 1.7e-80 270.4 0.2 2e-80 270.1 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin 6PF2K PF01591.18 ETS80202.1 - 1.5e-60 204.3 0.0 2.1e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ETS80202.1 - 9.4e-19 67.9 0.3 4.8e-18 65.6 0.3 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ZnuA PF01297.17 ETS80202.1 - 0.014 14.9 0.0 0.036 13.5 0.0 1.7 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic AAA_33 PF13671.6 ETS80202.1 - 0.035 14.3 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain UCH_1 PF13423.6 ETS80203.1 - 1.1e-30 107.3 0.0 4.6e-29 102.0 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 ETS80203.1 - 1.2e-14 54.5 0.0 1.1e-13 51.3 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase COesterase PF00135.28 ETS80204.1 - 4.3e-85 286.5 0.1 6e-72 243.2 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS80204.1 - 1.4e-08 34.9 0.0 2.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS80204.1 - 0.17 12.5 6.2 0.63 10.6 6.2 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Zn_clus PF00172.18 ETS80205.1 - 9e-09 35.3 4.7 2.2e-08 34.1 4.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS80205.1 - 4.5e-05 22.6 0.2 9.5e-05 21.5 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 ETS80206.1 - 6.3e-71 239.5 0.0 7.7e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RPE65 PF03055.15 ETS80207.1 - 2.5e-87 294.0 0.0 2.9e-87 293.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Abhydrolase_3 PF07859.13 ETS80208.1 - 3.3e-19 69.6 0.6 3.3e-14 53.2 0.4 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 ETS80208.1 - 7e-08 32.3 0.1 6.9e-05 22.5 0.1 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 ETS80208.1 - 2.4e-06 27.2 0.1 0.0009 18.8 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ETS80208.1 - 8.8e-06 25.2 0.5 0.057 12.7 0.0 2.4 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS80208.1 - 4.3e-05 24.2 1.8 6.1e-05 23.7 1.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 ETS80208.1 - 7e-05 22.9 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.7 ETS80208.1 - 0.00054 19.0 0.0 0.00076 18.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.25 ETS80208.1 - 0.002 18.0 0.0 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_1 PF00561.20 ETS80208.1 - 0.0084 15.8 0.0 0.068 12.8 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 ETS80208.1 - 0.011 15.6 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Chlorophyllase PF07224.11 ETS80208.1 - 0.017 14.2 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Esterase PF00756.20 ETS80208.1 - 0.025 14.2 0.2 0.047 13.3 0.0 1.5 2 0 0 2 2 2 0 Putative esterase COesterase PF00135.28 ETS80208.1 - 0.048 12.5 0.0 0.07 12.0 0.0 1.3 1 1 0 1 1 1 0 Carboxylesterase family Say1_Mug180 PF10340.9 ETS80208.1 - 0.18 10.6 1.1 0.52 9.1 1.1 1.7 1 1 0 1 1 1 0 Steryl acetyl hydrolase TPP_enzyme_N PF02776.18 ETS80209.1 - 2.7e-33 115.0 0.1 1.4e-32 112.6 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ETS80209.1 - 1.6e-17 63.7 0.0 2.8e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ETS80209.1 - 3.4e-09 36.6 0.0 1.2e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Peptidase_S15 PF02129.18 ETS80210.1 - 1.7e-36 126.2 0.0 7.8e-36 124.1 0.0 1.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ETS80210.1 - 2.7e-31 109.3 0.0 4e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Ribosomal_L5_C PF00673.21 ETS80211.1 - 1.5e-26 92.4 0.0 3.6e-26 91.1 0.0 1.7 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ETS80211.1 - 3e-07 30.6 0.2 6.7e-07 29.5 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Fes1 PF08609.10 ETS80212.1 - 3.6e-23 82.3 6.4 3e-22 79.3 2.6 2.7 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 Arm PF00514.23 ETS80212.1 - 0.00085 19.3 0.3 0.035 14.1 0.1 3.2 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 ETS80212.1 - 0.0042 17.2 0.6 0.31 11.4 0.0 3.5 3 1 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 ETS80212.1 - 0.024 15.0 2.7 1.6 9.2 2.6 3.0 1 1 1 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 ETS80212.1 - 0.039 14.5 4.6 1.1 9.8 0.1 3.8 2 1 4 6 6 6 0 HEAT-like repeat V-ATPase_H_N PF03224.14 ETS80212.1 - 0.094 12.0 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H Actin PF00022.19 ETS80213.1 - 6e-151 502.7 0.0 2.2e-150 500.8 0.0 1.7 1 1 0 1 1 1 1 Actin RF-1 PF00472.20 ETS80214.1 - 2.2e-24 85.6 2.1 2.2e-24 85.6 2.1 1.9 1 1 0 2 2 2 1 RF-1 domain WD40 PF00400.32 ETS80215.1 - 1.1e-32 111.5 15.1 0.00076 20.3 0.0 12.1 13 0 0 13 13 13 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS80215.1 - 5e-08 33.1 3.1 0.69 10.2 0.0 7.3 3 2 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS80215.1 - 0.11 11.4 0.4 7.4 5.4 0.0 3.7 4 2 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BDM PF10684.9 ETS80216.1 - 0.19 12.1 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative biofilm-dependent modulation protein OTT_1508_deam PF14441.6 ETS80217.1 - 1.4e-16 60.2 0.2 2.6e-16 59.4 0.2 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase Pkinase PF00069.25 ETS80218.1 - 6.4e-65 219.1 0.0 7.6e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS80218.1 - 9.6e-26 90.6 0.0 1.2e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS80218.1 - 2e-06 27.4 0.0 9.4e-06 25.1 0.0 1.8 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 ETS80218.1 - 0.00099 19.1 0.2 0.0092 15.9 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1229 PF06797.11 ETS80218.1 - 0.0063 16.7 0.2 0.01 16.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1229) Seadorna_VP7 PF07387.11 ETS80218.1 - 0.092 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 ETS80218.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ETS80218.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 MIF4G_like PF09088.11 ETS80219.1 - 7.7e-85 283.5 0.0 1.2e-84 282.9 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 ETS80219.1 - 3.1e-73 246.6 0.0 5.1e-73 245.8 0.0 1.4 1 0 0 1 1 1 1 MIF4G like Tape_meas_lam_C PF09718.10 ETS80219.1 - 0.037 14.1 0.4 0.1 12.7 0.4 1.7 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF2625 PF10946.8 ETS80219.1 - 0.056 12.5 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2625 Ribosomal_L4 PF00573.22 ETS80221.1 - 2.6e-33 115.4 0.4 3.5e-33 114.9 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 ETS80221.1 - 1.3e-27 95.6 0.5 1.3e-27 95.6 0.5 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Cohesin_load PF10345.9 ETS80222.1 - 6.2e-130 434.5 1.5 8.2e-130 434.0 1.5 1.2 1 0 0 1 1 1 1 Cohesin loading factor Abhydrolase_1 PF00561.20 ETS80223.1 - 3e-12 46.7 0.0 2.3e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS80223.1 - 1.8e-06 27.4 0.0 3.1e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 RAI1 PF08652.11 ETS80224.1 - 5e-28 97.1 0.2 1.4e-27 95.7 0.0 1.9 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease DUF3772 PF12607.8 ETS80225.1 - 0.11 12.3 0.6 0.18 11.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) BrnA_antitoxin PF14384.6 ETS80225.1 - 0.23 12.0 0.9 0.39 11.2 0.0 1.8 2 0 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system DUF410 PF04190.13 ETS80226.1 - 5.9e-89 298.2 0.0 7.4e-89 297.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Metal_resist PF13801.6 ETS80228.1 - 4.9 7.3 5.6 14 5.9 5.6 1.7 1 1 0 1 1 1 0 Heavy-metal resistance MFS_1 PF07690.16 ETS80229.1 - 6e-42 143.8 41.1 6e-42 143.8 41.1 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS80229.1 - 3.3e-17 62.5 29.4 3.5e-16 59.1 13.5 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 ETS80229.1 - 0.00011 20.7 15.6 0.00019 20.0 15.5 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MARVEL PF01284.23 ETS80230.1 - 3.4e-05 23.9 13.4 5.8e-05 23.2 13.4 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF4281 PF14108.6 ETS80230.1 - 0.0012 19.2 0.8 0.002 18.5 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) Nop16 PF09420.10 ETS80231.1 - 1.7e-65 221.0 5.6 1.9e-65 220.9 5.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Fungal_trans_2 PF11951.8 ETS80232.1 - 6.4e-56 189.8 0.1 1e-55 189.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS80232.1 - 1.5e-05 25.0 5.6 3e-05 24.0 5.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GSHPx PF00255.19 ETS80233.1 - 6.9e-39 131.8 0.1 8.7e-39 131.4 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 ETS80233.1 - 0.001 19.0 0.1 0.0029 17.5 0.1 1.7 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.6 ETS80233.1 - 0.0034 17.8 0.0 0.0075 16.7 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4174) Redoxin PF08534.10 ETS80233.1 - 0.0095 15.7 0.1 0.016 14.9 0.1 1.5 1 1 0 1 1 1 1 Redoxin DAO PF01266.24 ETS80234.1 - 2.9e-68 231.0 2.7 3.4e-68 230.8 2.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS80234.1 - 2.5e-05 23.7 0.2 0.0046 16.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS80234.1 - 4.6e-05 23.9 0.6 0.28 11.8 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS80234.1 - 8.5e-05 22.7 0.7 0.00025 21.2 0.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 ETS80234.1 - 0.00025 20.5 0.3 0.016 14.6 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase MCRA PF06100.11 ETS80234.1 - 0.00064 18.6 0.7 0.081 11.7 0.1 2.1 2 0 0 2 2 2 2 MCRA family Trp_halogenase PF04820.14 ETS80234.1 - 0.002 17.0 1.8 0.0064 15.4 0.3 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Sacchrp_dh_NADP PF03435.18 ETS80234.1 - 0.002 18.4 0.8 0.017 15.4 0.1 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 ETS80234.1 - 0.01 15.1 0.3 0.021 14.1 0.3 1.4 1 0 0 1 1 1 0 Thi4 family DHDPS PF00701.22 ETS80235.1 - 4.7e-35 120.7 0.0 5.4e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.22 ETS80236.1 - 3.6e-10 40.7 0.1 7.1e-10 39.7 0.1 1.6 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold EBP PF05241.12 ETS80237.1 - 1.2e-70 236.6 8.9 1.3e-70 236.4 8.9 1.0 1 0 0 1 1 1 1 Emopamil binding protein Sugar_tr PF00083.24 ETS80237.1 - 0.064 12.1 5.2 2.2 7.1 4.0 2.0 2 0 0 2 2 2 0 Sugar (and other) transporter TMEM208_SND2 PF05620.11 ETS80237.1 - 2.1 8.1 6.4 5 6.9 1.1 2.5 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 Peptidase_C48 PF02902.19 ETS80238.1 - 1e-34 120.3 0.0 2.6e-34 119.0 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Zn_clus PF00172.18 ETS80239.1 - 1.1e-07 31.8 8.1 2e-07 31.0 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 ETS80240.1 - 6.7e-46 157.0 0.0 9.5e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NEL PF14496.6 ETS80240.1 - 0.029 13.8 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting EptA_B_N PF08019.12 ETS80241.1 - 0.038 13.9 6.1 2.3 8.1 1.0 2.5 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB Methyltransf_2 PF00891.18 ETS80242.1 - 3.2e-25 88.6 0.0 6e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 ETS80242.1 - 1.3e-07 31.5 0.0 2.6e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 ETS80242.1 - 0.0064 16.5 0.0 0.019 15.0 0.0 1.8 1 0 0 1 1 1 1 Dimerisation domain HTH_Crp_2 PF13545.6 ETS80242.1 - 0.037 14.0 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Exc PF07825.11 ETS80242.1 - 0.16 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Excisionase-like protein DUF1454 PF07305.12 ETS80243.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) HET PF06985.11 ETS80244.1 - 2e-13 50.9 4.9 3.2e-10 40.6 0.7 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.11 ETS80245.1 - 2.7e-11 44.0 8.7 3.6e-09 37.1 2.3 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Exo_endo_phos PF03372.23 ETS80246.1 - 5.5e-11 42.4 2.5 3.3e-10 39.9 0.2 2.7 3 0 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family FBPase_glpX PF03320.13 ETS80246.1 - 0.1 11.5 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded adh_short_C2 PF13561.6 ETS80247.1 - 4.3e-48 163.9 0.2 5.8e-48 163.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS80247.1 - 4.7e-43 146.9 0.1 7.7e-43 146.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS80247.1 - 6.1e-11 42.6 0.9 9.6e-11 41.9 0.9 1.2 1 0 0 1 1 1 1 KR domain RRF PF01765.19 ETS80247.1 - 0.12 12.4 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosome recycling factor N2227 PF07942.12 ETS80248.1 - 4.7e-101 337.6 0.0 6e-101 337.2 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 ETS80248.1 - 0.0002 22.0 0.0 0.0012 19.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS80248.1 - 0.0017 18.2 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS80248.1 - 0.007 17.0 0.0 0.022 15.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS80248.1 - 0.051 13.4 0.0 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PAC4 PF16093.5 ETS80249.1 - 1.3e-21 76.6 0.0 1.9e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 HEAT_EZ PF13513.6 ETS80250.1 - 7.1e-30 103.0 13.2 2.3e-15 56.7 0.0 10.3 9 2 3 12 12 12 4 HEAT-like repeat HEAT PF02985.22 ETS80250.1 - 2.4e-27 92.6 15.8 3.1e-06 27.0 0.0 10.3 11 0 0 11 11 9 5 HEAT repeat HEAT_2 PF13646.6 ETS80250.1 - 7.6e-21 74.3 7.7 2.7e-07 30.9 0.0 7.6 6 3 4 10 10 8 3 HEAT repeats Cnd1 PF12717.7 ETS80250.1 - 4.1e-11 43.2 0.1 0.1 12.6 0.0 5.5 5 1 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ETS80250.1 - 2.6e-10 40.8 0.0 0.12 12.9 0.0 6.9 5 2 4 9 9 9 3 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 ETS80250.1 - 5.4e-09 35.7 0.7 0.12 11.5 0.0 5.1 5 1 0 5 5 5 3 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 ETS80250.1 - 3.1e-07 29.4 0.0 0.018 13.7 0.0 3.5 3 1 0 3 3 3 2 Adaptin N terminal region IBN_N PF03810.19 ETS80250.1 - 1.4e-05 24.9 0.0 0.00019 21.3 0.0 3.0 1 1 0 1 1 1 1 Importin-beta N-terminal domain Arm PF00514.23 ETS80250.1 - 3.3e-05 23.8 3.0 0.41 10.8 0.0 6.3 6 1 0 6 6 6 1 Armadillo/beta-catenin-like repeat DUF3437 PF11919.8 ETS80250.1 - 0.003 17.5 0.1 2.5 8.1 0.0 4.7 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) RTP1_C1 PF10363.9 ETS80250.1 - 0.0054 16.9 0.1 0.13 12.5 0.0 3.1 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 ETS80250.1 - 0.02 14.6 0.1 5.3 6.7 0.0 4.2 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis TAF6_C PF07571.13 ETS80250.1 - 0.025 14.9 0.0 6.9 7.1 0.0 4.0 4 1 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain HEAT_PBS PF03130.16 ETS80250.1 - 0.068 13.9 6.9 1.4 9.8 0.0 5.4 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Acetyltransf_7 PF13508.7 ETS80251.1 - 1.1e-05 25.8 0.0 6e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS80251.1 - 1.1e-05 25.4 0.0 0.0002 21.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS80251.1 - 0.0003 21.0 0.0 0.00068 19.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ETS80251.1 - 0.056 13.4 0.0 0.21 11.6 0.0 2.0 2 1 0 2 2 2 0 FR47-like protein p450 PF00067.22 ETS80252.1 - 6.1e-09 35.1 0.0 6.2e-06 25.2 0.0 2.8 2 1 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 ETS80253.1 - 5.1e-42 144.1 49.1 5.1e-42 144.1 49.1 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS80253.1 - 6e-12 44.8 23.5 6e-12 44.8 23.5 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS80253.1 - 1.6e-10 40.5 13.1 1.6e-10 40.5 13.1 3.2 2 1 0 3 3 3 2 Sugar (and other) transporter CorA PF01544.18 ETS80255.1 - 1e-05 25.0 0.1 2.1e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF5582 PF17819.1 ETS80255.1 - 0.02 15.3 0.1 0.038 14.5 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5582) DUF2207 PF09972.9 ETS80255.1 - 0.028 13.2 0.1 0.041 12.7 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HET PF06985.11 ETS80257.1 - 9.7e-32 110.3 0.1 1.4e-31 109.8 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 ETS80258.1 - 9e-07 28.2 0.4 1.9e-06 27.1 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain MSA_2 PF00985.17 ETS80258.1 - 0.5 10.7 4.6 0.82 10.0 4.6 1.3 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Arginase PF00491.21 ETS80259.1 - 2.6e-81 273.2 0.6 3.3e-81 272.9 0.6 1.0 1 0 0 1 1 1 1 Arginase family AMP-binding PF00501.28 ETS80260.1 - 1.3e-99 333.7 0.0 2.1e-99 333.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 ETS80260.1 - 2.3e-78 263.3 0.7 4.8e-78 262.2 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ETS80260.1 - 4.5e-60 202.6 3.8 6.1e-58 195.7 0.6 3.1 3 0 0 3 3 3 2 KR domain NAD_binding_4 PF07993.12 ETS80260.1 - 1.2e-50 172.1 0.0 5.5e-49 166.6 0.0 2.9 2 1 0 2 2 2 1 Male sterility protein Acyl_transf_1 PF00698.21 ETS80260.1 - 5e-46 157.7 0.0 8.1e-39 134.0 0.3 2.4 1 1 1 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ETS80260.1 - 8.1e-44 148.4 0.6 1.9e-43 147.2 0.6 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 ETS80260.1 - 1.1e-22 80.1 0.3 6.4e-11 42.4 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 ETS80260.1 - 5.7e-13 49.3 0.0 6.9e-12 45.8 0.0 2.8 3 0 0 3 3 2 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 ETS80260.1 - 4.3e-11 42.7 0.0 3.7e-06 26.6 0.0 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 ETS80260.1 - 5.2e-11 43.4 0.0 1.5e-10 41.9 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 ETS80260.1 - 2.7e-08 33.6 0.0 0.0047 16.4 0.0 2.5 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase adh_short PF00106.25 ETS80260.1 - 1.7e-07 30.9 0.2 1.3e-05 24.8 0.1 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.23 ETS80260.1 - 6.6e-06 25.7 0.1 2.2e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain NmrA PF05368.13 ETS80260.1 - 2.1e-05 24.2 0.3 0.16 11.5 0.1 2.7 2 0 0 2 2 2 2 NmrA-like family Polysacc_synt_2 PF02719.15 ETS80260.1 - 0.0002 20.6 0.0 0.43 9.7 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ETS80260.1 - 0.03 13.3 0.0 1.5 7.8 0.0 2.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ETS80260.1 - 0.31 10.1 4.3 15 4.6 0.3 3.6 3 1 0 3 3 3 0 RmlD substrate binding domain NmrA PF05368.13 ETS80261.1 - 2.7e-19 69.7 0.0 3.6e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS80261.1 - 4.1e-09 36.6 0.0 7.3e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 ETS80261.1 - 1.5e-06 28.3 0.1 2.3e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS80261.1 - 2e-05 24.2 0.1 0.00016 21.3 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 ETS80261.1 - 0.021 15.4 0.0 0.045 14.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 ETS80261.1 - 0.026 13.9 0.1 0.068 12.6 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ETS80261.1 - 0.041 12.9 0.0 0.059 12.4 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 ETS80261.1 - 0.21 11.7 0.1 0.45 10.7 0.1 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PhyH PF05721.13 ETS80262.1 - 2e-36 126.2 0.1 2.5e-36 125.9 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 ETS80262.1 - 0.00055 18.8 0.0 0.00098 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) DUF5070 PF16802.5 ETS80262.1 - 0.084 12.9 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5070) AATase PF07247.12 ETS80263.1 - 0.0028 16.3 0.0 0.006 15.2 0.0 1.6 1 1 0 1 1 1 1 Alcohol acetyltransferase Abhydrolase_3 PF07859.13 ETS80264.1 - 7.4e-24 84.8 0.0 1e-23 84.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS80264.1 - 3e-11 42.8 0.0 4.4e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 ETS80264.1 - 0.084 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4978 PF16349.5 ETS80266.1 - 7.8e-15 54.9 0.8 1.8e-14 53.8 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4978) TGT_C2 PF14810.6 ETS80266.1 - 0.15 12.2 0.0 2.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Patch-forming domain C2 of tRNA-guanine transglycosylase Wzz PF02706.15 ETS80267.1 - 0.098 13.0 2.7 11 6.4 0.6 2.8 2 0 0 2 2 2 0 Chain length determinant protein HET PF06985.11 ETS80268.1 - 1.7e-31 109.5 0.5 3.2e-31 108.6 0.5 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.7 ETS80269.1 - 0.0025 17.7 0.0 0.0063 16.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like Fungal_trans_2 PF11951.8 ETS80270.1 - 2.5e-09 36.5 0.1 1.5e-08 33.9 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS80270.1 - 0.00039 20.5 9.6 0.00071 19.7 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.21 ETS80271.1 - 2e-06 27.4 0.1 3.3e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_C PF00775.21 ETS80272.1 - 2.8e-06 26.9 0.0 0.0004 19.9 0.0 2.3 2 0 0 2 2 2 2 Dioxygenase Zn_clus PF00172.18 ETS80273.1 - 2.7e-08 33.8 12.4 4.6e-08 33.1 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS80273.1 - 9.2e-05 21.4 0.1 0.00015 20.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_12 PF13424.6 ETS80274.1 - 5.8e-26 90.6 10.8 1.3e-09 38.2 0.4 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 ETS80274.1 - 1.2e-18 66.3 10.8 0.00021 21.0 0.0 6.2 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 ETS80274.1 - 2.5e-15 56.7 5.7 0.0031 18.0 0.0 5.4 1 1 4 5 5 5 5 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS80274.1 - 3.2e-15 56.1 2.5 0.003 17.8 0.0 6.1 1 1 2 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 ETS80274.1 - 2.1e-14 52.4 0.4 1 9.6 0.0 7.5 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 ETS80274.1 - 3.3e-14 52.4 4.5 0.49 11.3 0.4 6.9 6 1 0 6 6 6 4 Tetratricopeptide repeat Patatin PF01734.22 ETS80274.1 - 5.6e-14 52.8 0.1 1.4e-13 51.5 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.22 ETS80274.1 - 1.9e-13 50.2 0.0 4.6e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_20 PF14561.6 ETS80274.1 - 3.2e-11 43.4 8.8 0.011 16.1 0.1 6.3 1 1 5 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 ETS80274.1 - 3.7e-11 42.2 10.0 0.96 9.6 0.1 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 ETS80274.1 - 1.5e-10 40.4 0.1 1.3 9.4 0.0 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 ETS80274.1 - 4.8e-09 36.3 1.2 0.79 10.5 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 ETS80274.1 - 2.2e-06 27.2 0.5 14 5.7 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 ETS80274.1 - 2.7e-06 27.9 13.2 0.042 14.5 0.5 6.6 6 1 1 7 7 5 3 Tetratricopeptide repeat PPR PF01535.20 ETS80274.1 - 5.3e-06 26.3 0.1 2.5 8.6 0.0 5.6 5 0 0 5 5 5 1 PPR repeat VWA_2 PF13519.6 ETS80274.1 - 4.7e-05 24.0 0.5 5 7.8 0.0 5.7 6 0 0 6 6 5 1 von Willebrand factor type A domain TPR_4 PF07721.14 ETS80274.1 - 6.8e-05 23.1 1.5 1 10.2 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 ETS80274.1 - 0.00053 20.2 6.4 2.9 8.5 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 ETS80274.1 - 0.00094 18.8 2.5 5.5 6.8 0.1 5.2 5 1 0 5 5 4 1 TPR repeat BTAD PF03704.17 ETS80274.1 - 0.0031 18.0 2.4 0.93 9.9 0.1 3.2 1 1 2 3 3 3 1 Bacterial transcriptional activator domain YfdX PF10938.8 ETS80274.1 - 0.0032 17.4 3.5 8.3 6.3 0.0 4.4 3 1 0 3 3 3 0 YfdX protein NACHT PF05729.12 ETS80274.1 - 0.038 13.9 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain HTH_27 PF13463.6 ETS80274.1 - 0.08 13.4 0.3 0.4 11.2 0.1 2.4 2 0 0 2 2 1 0 Winged helix DNA-binding domain AAA_25 PF13481.6 ETS80274.1 - 0.1 12.1 0.0 0.36 10.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF4248 PF14053.6 ETS80274.1 - 0.14 12.2 0.1 44 4.2 0.0 3.8 4 0 0 4 4 3 0 Domain of unknown function (DUF4248) ELYS PF13934.6 ETS80274.1 - 0.23 11.4 1.5 10 6.1 0.0 3.2 2 1 2 4 4 4 0 Nuclear pore complex assembly GATA PF00320.27 ETS80275.1 - 4e-05 23.1 2.8 0.01 15.4 0.2 2.6 2 0 0 2 2 2 2 GATA zinc finger ECH_2 PF16113.5 ETS80276.1 - 5.6e-125 417.3 0.0 7.4e-125 416.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ETS80276.1 - 1.1e-26 93.6 0.1 2.3e-25 89.3 0.0 2.3 3 0 0 3 3 3 1 Enoyl-CoA hydratase/isomerase LSM PF01423.22 ETS80277.1 - 6.6e-18 64.2 0.1 8.8e-18 63.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 ETS80277.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Dak1 PF02733.17 ETS80278.1 - 1.6e-107 359.0 2.4 2.4e-107 358.4 2.4 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 ETS80278.1 - 1.1e-45 155.7 0.1 2.5e-45 154.5 0.1 1.7 1 0 0 1 1 1 1 DAK2 domain IF-2B PF01008.17 ETS80279.1 - 1.4e-52 178.7 0.1 3.8e-52 177.3 0.1 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family COMPASS-Shg1 PF05205.12 ETS80281.1 - 1.2e-24 86.9 0.1 3.6e-24 85.4 0.1 1.9 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 SPRY PF00622.28 ETS80282.1 - 1.7e-18 66.9 0.0 3.2e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 SPRY domain DUF3446 PF11928.8 ETS80282.1 - 0.016 15.5 3.9 0.016 15.5 3.9 2.1 2 0 0 2 2 2 0 Early growth response N-terminal domain Apc13p PF05839.11 ETS80283.1 - 2.7e-29 101.2 0.0 3.1e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Apc13p protein TRAPP PF04051.16 ETS80284.1 - 1.3e-37 128.7 0.0 1.5e-37 128.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CRAL_TRIO PF00650.20 ETS80285.1 - 6.8e-42 142.9 0.0 1e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ETS80285.1 - 6.8e-15 55.0 0.9 1.5e-14 53.9 0.9 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ETS80285.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.10 ETS80286.1 - 4.5e-76 256.1 0.0 6e-76 255.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 ETS80286.1 - 8e-42 143.0 0.0 1.1e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B KfrA_N PF11740.8 ETS80286.1 - 0.0044 17.7 0.0 0.012 16.3 0.0 1.7 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term MFAP1 PF06991.11 ETS80287.1 - 5.4e-74 248.7 26.0 5.4e-74 248.7 26.0 3.6 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing UCH PF00443.29 ETS80288.1 - 1.1e-34 120.1 0.1 1.8e-34 119.4 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ETS80288.1 - 1.3e-06 28.3 8.3 3.4e-06 26.9 8.3 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alb1 PF09135.11 ETS80289.1 - 3.1e-26 92.3 17.7 3.1e-26 92.3 17.7 1.4 2 0 0 2 2 2 1 Alb1 RNase_E_G PF10150.9 ETS80289.1 - 0.00039 19.9 3.7 0.00048 19.6 3.7 1.1 1 0 0 1 1 1 1 Ribonuclease E/G family SesA PF17107.5 ETS80289.1 - 0.046 13.9 2.3 0.058 13.6 0.9 1.8 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases V_ATPase_I PF01496.19 ETS80289.1 - 0.52 8.2 5.9 0.57 8.0 5.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mit_KHE1 PF10173.9 ETS80289.1 - 0.53 10.3 2.5 0.69 10.0 2.5 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related TMPIT PF07851.13 ETS80289.1 - 1.1 8.5 4.0 1.2 8.3 4.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein Kin17_mid PF10357.9 ETS80290.1 - 2.9e-54 182.3 1.9 2.9e-54 182.3 1.9 2.1 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 ETS80290.1 - 2.6e-05 24.4 3.4 4.7e-05 23.6 3.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ETS80290.1 - 3e-05 24.2 2.2 5.7e-05 23.3 2.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Methyltransf_7 PF03492.15 ETS80290.1 - 0.0049 16.1 0.1 0.01 15.1 0.1 1.5 1 1 0 1 1 1 1 SAM dependent carboxyl methyltransferase zf-C2H2_2 PF12756.7 ETS80290.1 - 0.0096 16.2 0.7 0.0096 16.2 0.7 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF4407 PF14362.6 ETS80290.1 - 6.9 5.9 11.8 10 5.4 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4748 PF15932.5 ETS80291.1 - 1.2e-24 85.8 0.1 1.5e-24 85.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) CTD_bind PF04818.13 ETS80294.1 - 5.4e-11 43.2 0.1 1.4e-10 41.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RSRP PF17069.5 ETS80294.1 - 0.98 8.9 47.0 1.6 8.2 47.0 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Tau95 PF09734.9 ETS80295.1 - 6.9e-38 130.6 0.6 1.4e-37 129.6 0.6 1.6 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 ETS80295.1 - 2.3e-34 118.3 0.0 3.9e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 Tau95 Triple barrel domain Ribos_L4_asso_C PF14374.6 ETS80295.1 - 0.13 12.4 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain VP4_haemagglut PF00426.18 ETS80295.1 - 0.15 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) Concanavalin-like domain B56 PF01603.20 ETS80296.1 - 1.1e-192 640.6 5.3 1.3e-192 640.4 5.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 ETS80296.1 - 0.00034 20.6 2.2 0.29 11.0 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Questin_oxidase PF14027.6 ETS80297.1 - 7.7e-87 292.0 2.8 9.3e-87 291.7 2.8 1.1 1 0 0 1 1 1 1 Questin oxidase-like Kelch_5 PF13854.6 ETS80298.1 - 7.3e-08 32.2 5.5 5.5e-07 29.4 0.1 4.1 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.25 ETS80298.1 - 0.00059 19.4 7.6 9.3 5.9 0.0 5.7 5 1 1 6 6 6 3 Kelch motif Kelch_3 PF13415.6 ETS80298.1 - 0.0097 16.2 5.9 0.03 14.6 0.0 4.2 5 0 0 5 5 5 1 Galactose oxidase, central domain SKG6 PF08693.10 ETS80298.1 - 0.075 12.5 0.2 0.19 11.2 0.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 ETS80298.1 - 0.13 12.2 0.1 0.36 10.8 0.1 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Adeno_E3_CR2 PF02439.15 ETS80298.1 - 0.28 11.0 1.0 0.48 10.2 1.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Kelch_4 PF13418.6 ETS80298.1 - 3.2 7.8 10.2 1.1 9.3 0.0 4.0 4 0 0 4 4 4 0 Galactose oxidase, central domain ubiquitin PF00240.23 ETS80299.1 - 2.2e-05 24.1 0.0 5.8e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 ETS80299.1 - 0.00024 21.6 1.3 0.0011 19.4 1.3 2.2 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain PS_Dcarbxylase PF02666.15 ETS80300.1 - 6.3e-78 260.9 0.0 2.4e-76 255.7 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Cyt_b-c1_8 PF10890.8 ETS80300.1 - 0.075 13.4 0.1 5.6 7.4 0.0 2.5 2 0 0 2 2 2 0 Cytochrome b-c1 complex subunit 8 Asparaginase PF00710.20 ETS80301.1 - 2.3e-60 203.4 0.0 3.3e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 ETS80301.1 - 1.9e-28 99.0 0.0 2.1e-27 95.6 0.0 2.2 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 ETS80301.1 - 1.7e-08 34.9 0.2 8e-08 32.8 0.2 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS80301.1 - 4.4e-07 30.3 0.2 4.1e-05 24.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS80301.1 - 2.2e-06 27.8 0.1 0.01 16.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ETS80301.1 - 4.9e-05 23.5 0.5 0.0026 18.0 0.3 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS80301.1 - 0.00023 21.3 0.1 0.31 11.7 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat AMP-binding PF00501.28 ETS80303.1 - 1.4e-23 83.2 0.0 4.4e-22 78.3 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme Glyco_hydro_43 PF04616.14 ETS80304.1 - 1.1e-34 120.1 5.4 1.8e-34 119.4 5.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ETS80304.1 - 1.9e-21 76.7 0.0 2.7e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF5017 PF16409.5 ETS80304.1 - 0.016 14.7 0.4 2.8 7.4 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5017) NAP PF00956.18 ETS80305.1 - 3.1e-30 105.3 8.6 3.6e-29 101.8 8.6 2.1 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Glyco_hydro_76 PF03663.14 ETS80306.1 - 8.5e-160 532.2 13.5 9.8e-160 532.0 13.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 ETS80306.1 - 0.00053 19.2 8.2 0.18 10.9 0.3 3.2 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 IF3_C PF00707.22 ETS80307.1 - 1.8e-08 34.2 0.1 3.8e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 ETS80307.1 - 3.3e-07 30.1 0.3 4.2e-06 26.5 0.5 2.1 2 0 0 2 2 2 1 Mitochondrial translation initiation factor IF3_N PF05198.16 ETS80307.1 - 0.0045 17.2 0.6 0.088 13.1 0.1 2.7 3 0 0 3 3 3 1 Translation initiation factor IF-3, N-terminal domain Ligase_CoA PF00549.19 ETS80307.1 - 0.063 13.1 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 CoA-ligase SAVED PF18145.1 ETS80307.1 - 0.12 12.2 0.3 0.2 11.4 0.3 1.4 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain Peptidase_S24 PF00717.23 ETS80308.1 - 3.6e-05 23.6 0.0 7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 ETS80308.1 - 0.0031 17.3 0.0 0.043 13.6 0.0 2.1 1 1 0 2 2 2 1 Signal peptidase, peptidase S26 Arm PF00514.23 ETS80309.1 - 7.7e-76 248.1 32.8 1.5e-13 50.3 0.1 11.2 11 0 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 ETS80309.1 - 9.9e-18 64.3 13.5 0.00014 22.3 0.2 7.7 5 1 3 8 8 7 5 HEAT-like repeat HEAT_2 PF13646.6 ETS80309.1 - 6.3e-17 61.8 12.1 7.9e-05 23.0 0.1 7.3 3 3 4 7 7 7 4 HEAT repeats HEAT PF02985.22 ETS80309.1 - 8.6e-16 56.7 15.9 0.069 13.5 0.3 8.7 10 0 0 10 10 8 5 HEAT repeat Adaptin_N PF01602.20 ETS80309.1 - 7.6e-14 51.2 7.7 2.2e-07 29.9 0.2 3.2 2 1 1 3 3 3 3 Adaptin N terminal region Arm_2 PF04826.13 ETS80309.1 - 6.8e-12 45.4 7.2 6e-07 29.2 2.9 2.7 1 1 1 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.14 ETS80309.1 - 5.4e-09 35.8 3.0 0.00013 21.4 1.3 3.5 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.12 ETS80309.1 - 1e-08 33.8 2.0 1.8e-08 33.0 2.0 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Cnd1 PF12717.7 ETS80309.1 - 2.1e-05 24.7 7.2 0.1 12.6 0.1 5.0 1 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 ETS80309.1 - 6e-05 23.0 6.9 0.96 9.4 0.0 4.2 2 1 3 5 5 5 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 ETS80309.1 - 6.1e-05 23.1 1.5 6 7.0 0.2 5.1 2 1 6 8 8 8 1 V-ATPase subunit H DUF5578 PF17741.1 ETS80309.1 - 0.00024 20.6 6.0 1.5 8.2 0.0 4.8 2 2 3 5 5 5 2 Family of unknown function (DUF5578) IFRD PF05004.13 ETS80309.1 - 0.0013 17.9 3.5 2.6 7.1 0.0 4.0 3 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) HEAT_PBS PF03130.16 ETS80309.1 - 0.0033 17.9 6.8 8.9 7.3 0.4 6.7 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 ETS80309.1 - 0.033 14.8 0.1 1.6 9.4 0.1 3.2 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region Atx10homo_assoc PF09759.9 ETS80309.1 - 0.051 13.6 7.5 2.2 8.4 0.4 4.4 4 2 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain UNC45-central PF11701.8 ETS80309.1 - 0.053 13.5 4.1 1.9 8.4 0.3 3.8 4 1 0 4 4 4 0 Myosin-binding striated muscle assembly central CBS PF00571.28 ETS80310.1 - 3.5e-25 88.2 6.1 2e-09 37.7 0.0 4.3 4 0 0 4 4 4 4 CBS domain RhoGAP PF00620.27 ETS80311.1 - 4.7e-11 42.7 0.0 9.6e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain SSURE PF11966.8 ETS80313.1 - 0.15 11.8 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Fibronectin-binding repeat Metallophos PF00149.28 ETS80314.1 - 7e-20 72.4 0.2 1.2e-19 71.7 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ETS80314.1 - 6.8e-06 26.4 0.0 0.00011 22.5 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Nitroreductase PF00881.24 ETS80315.1 - 7.3e-17 61.9 0.0 8.9e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family FAD_binding_1 PF00667.20 ETS80316.1 - 4.3e-47 160.5 0.0 5.8e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 ETS80316.1 - 8.9e-10 39.2 0.0 3.9e-09 37.1 0.0 2.1 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain adh_short PF00106.25 ETS80317.1 - 5.6e-25 87.9 2.3 3e-20 72.5 1.5 2.6 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS80317.1 - 3.3e-16 59.5 0.7 7.6e-14 51.8 0.7 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS80317.1 - 1.8e-05 24.8 0.1 3e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS80317.1 - 0.00025 20.6 0.0 0.00062 19.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 ETS80317.1 - 0.14 12.0 0.2 0.25 11.2 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ank_2 PF12796.7 ETS80318.1 - 1.7e-21 76.6 0.6 4.2e-10 40.1 0.0 5.1 5 1 1 6 6 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS80318.1 - 1.5e-14 54.1 1.8 0.0019 18.7 0.0 6.8 6 1 0 7 7 7 2 Ankyrin repeats (many copies) NACHT PF05729.12 ETS80318.1 - 9.2e-14 51.7 0.1 3.7e-13 49.7 0.1 2.2 2 0 0 2 2 2 1 NACHT domain Ank_5 PF13857.6 ETS80318.1 - 2.1e-12 47.0 1.3 1.1e-07 32.0 0.0 4.8 4 2 3 7 7 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS80318.1 - 1.8e-10 40.1 7.0 0.015 15.8 0.0 8.1 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 ETS80318.1 - 3.6e-06 27.2 6.8 0.0016 18.8 0.0 5.1 6 0 0 6 6 4 1 Ankyrin repeat AAA_16 PF13191.6 ETS80318.1 - 3e-05 24.5 0.1 0.0001 22.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 ETS80318.1 - 0.00047 19.4 0.3 0.002 17.4 0.0 2.1 3 0 0 3 3 3 1 NB-ARC domain AAA_22 PF13401.6 ETS80318.1 - 0.0014 18.9 0.0 0.005 17.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ETS80318.1 - 0.002 18.5 0.0 0.006 17.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 ETS80318.1 - 0.016 15.6 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 ETS80318.1 - 0.029 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 ETS80318.1 - 0.1 13.1 0.0 0.34 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ETS80318.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1563 PF07599.11 ETS80318.1 - 0.41 10.8 2.5 3.2 7.9 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1563) SNF2_N PF00176.23 ETS80319.1 - 6.5e-59 199.4 0.2 1e-58 198.7 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS80319.1 - 2.3e-11 44.0 0.0 1e-10 41.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS80319.1 - 5.1e-07 29.8 0.1 1.3e-06 28.6 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ETS80319.1 - 1.1e-05 25.3 0.0 2.9e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 ETS80319.1 - 0.012 15.2 0.4 0.025 14.2 0.0 1.7 2 0 0 2 2 2 0 DEAD_2 p450 PF00067.22 ETS80320.1 - 6.4e-43 147.2 0.1 8.6e-43 146.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 CVNH PF08881.10 ETS80321.1 - 2e-11 44.5 0.1 2.7e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 CVNH domain NACHT PF05729.12 ETS80322.1 - 1.2e-08 35.1 0.1 3e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS80322.1 - 2.6e-06 27.9 0.1 1.3e-05 25.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS80322.1 - 6.3e-05 23.3 0.1 0.00039 20.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 ETS80322.1 - 0.0025 17.8 0.0 0.28 11.2 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 ETS80322.1 - 0.0054 17.1 2.1 0.024 15.0 0.0 3.0 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 ETS80322.1 - 0.016 15.7 0.1 0.052 14.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Viral_helicase1 PF01443.18 ETS80322.1 - 0.063 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 ETS80322.1 - 0.083 12.8 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 ETS80322.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 ETS80322.1 - 0.15 12.4 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ETS80322.1 - 0.16 11.9 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 NTPase CoiA PF06054.11 ETS80322.1 - 0.16 11.1 0.6 0.27 10.3 0.6 1.2 1 0 0 1 1 1 0 Competence protein CoiA-like family AAA_29 PF13555.6 ETS80322.1 - 0.19 11.5 0.3 0.42 10.4 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Methyltransf_11 PF08241.12 ETS80323.1 - 0.00044 20.8 0.0 0.00088 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS80323.1 - 0.0008 20.1 0.0 0.0021 18.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FAM220 PF15487.6 ETS80323.1 - 0.0067 16.1 0.4 0.0067 16.1 0.4 4.7 5 1 0 5 5 5 1 FAM220 family Methyltransf_23 PF13489.6 ETS80323.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 ETS80323.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase SAP PF02037.27 ETS80324.1 - 2.2e-13 49.6 0.1 3.8e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 ETS80324.1 - 0.033 13.9 0.3 0.071 12.8 0.3 1.5 1 0 0 1 1 1 0 HeH/LEM domain Tho1_MOS11_C PF18592.1 ETS80324.1 - 0.2 11.5 10.4 0.054 13.3 3.7 2.9 2 1 0 2 2 2 0 Tho1/MOS11 C-terminal domain API5 PF05918.11 ETS80324.1 - 1.3 7.8 4.0 1.7 7.4 4.0 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ras PF00071.22 ETS80326.1 - 2.2e-38 131.4 0.0 2.9e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS80326.1 - 3.2e-15 56.4 0.0 5e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS80326.1 - 0.00084 18.8 0.0 0.0017 17.9 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family GST_N PF02798.20 ETS80327.1 - 1.8e-14 53.8 0.0 3.6e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ETS80327.1 - 1e-13 51.5 0.0 1.7e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ETS80327.1 - 4.7e-11 42.8 0.0 9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ETS80327.1 - 3.1e-10 40.1 0.0 6.3e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ETS80327.1 - 9.7e-09 35.3 0.0 1.5e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ETS80327.1 - 8.4e-06 25.7 0.0 1.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain 6PGD PF00393.19 ETS80328.1 - 1.2e-93 313.6 0.0 1.5e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ETS80328.1 - 1.9e-35 122.3 0.0 3.3e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 ETS80328.1 - 6.6e-06 26.1 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 ETS80328.1 - 1.6e-05 24.6 0.0 2.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 ETS80328.1 - 0.004 17.1 0.0 0.0092 16.0 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 ETS80328.1 - 0.0053 17.3 0.0 0.012 16.1 0.0 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 ETS80328.1 - 0.0087 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 ETS80328.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.6 ETS80328.1 - 0.023 14.9 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Raptor_N PF14538.6 ETS80329.1 - 0.00067 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Peptidase_C14 PF00656.22 ETS80329.1 - 0.0015 18.5 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 Caspase domain zf-rbx1 PF12678.7 ETS80331.1 - 3.7e-10 39.9 0.8 6.9e-10 39.1 0.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ETS80331.1 - 4.1e-08 33.4 5.1 4.9e-08 33.2 1.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 ETS80331.1 - 7e-07 29.0 0.8 1.2e-06 28.3 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ETS80331.1 - 1.5e-06 28.1 1.4 3.2e-06 27.0 1.4 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ETS80331.1 - 1.6e-06 27.9 4.7 1e-05 25.2 1.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS80331.1 - 5.6e-06 26.3 2.1 4e-05 23.5 0.2 2.9 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ETS80331.1 - 5.4e-05 23.0 1.6 0.00012 21.8 1.6 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ETS80331.1 - 0.00064 19.5 4.6 0.00067 19.5 1.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 ETS80331.1 - 0.0032 17.0 0.8 0.0084 15.7 0.8 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 ETS80331.1 - 0.005 16.5 0.7 0.005 16.5 0.7 3.2 3 0 0 3 3 3 1 RING-like zinc finger zf-ANAPC11 PF12861.7 ETS80331.1 - 0.011 15.8 0.6 0.027 14.5 0.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PQ-loop PF04193.14 ETS80331.1 - 0.052 13.3 1.1 0.17 11.7 1.1 1.9 1 0 0 1 1 1 0 PQ loop repeat FA_desaturase PF00487.24 ETS80331.1 - 0.1 12.4 0.1 0.1 12.4 0.1 2.3 2 0 0 2 2 2 0 Fatty acid desaturase DUF2921 PF11145.8 ETS80331.1 - 0.27 9.0 0.5 0.39 8.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-C3H2C3 PF17122.5 ETS80331.1 - 1.5 8.9 3.9 6.7 6.8 1.0 2.4 2 0 0 2 2 2 0 Zinc-finger FANCL_C PF11793.8 ETS80331.1 - 2.4 8.4 4.3 8.7 6.6 4.3 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain HSBP1 PF06825.12 ETS80332.1 - 2.1e-17 62.7 1.0 2.4e-17 62.5 1.0 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF1664 PF07889.12 ETS80332.1 - 0.0089 16.1 0.3 0.01 15.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) CLZ PF16526.5 ETS80332.1 - 0.016 15.6 0.0 0.02 15.2 0.0 1.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Matrilin_ccoil PF10393.9 ETS80332.1 - 0.033 14.0 0.1 0.19 11.6 0.1 2.0 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Thioredoxin PF00085.20 ETS80333.1 - 5.3e-59 196.6 0.0 2e-30 104.8 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 ETS80333.1 - 1.3e-25 90.1 0.7 3.6e-25 88.7 0.2 2.0 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 ETS80333.1 - 1.3e-17 64.3 0.0 3.9e-09 36.9 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 ETS80333.1 - 7.5e-13 48.5 0.0 1.9e-05 24.2 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 ETS80333.1 - 2.5e-08 33.9 0.2 0.0042 17.0 0.0 2.5 1 1 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 ETS80333.1 - 3.9e-08 33.4 0.0 0.0083 16.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 ETS80333.1 - 9.9e-08 32.2 0.0 0.014 15.7 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like HyaE PF07449.11 ETS80333.1 - 4e-06 26.8 0.0 0.0024 17.8 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE ERp29_N PF07912.13 ETS80333.1 - 4.3e-06 26.9 0.1 4.8e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 ERp29, N-terminal domain Thioredoxin_9 PF14595.6 ETS80333.1 - 8.8e-06 25.5 0.0 0.0031 17.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin TraF PF13728.6 ETS80333.1 - 1.7e-05 24.8 0.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 2 F plasmid transfer operon protein Redoxin PF08534.10 ETS80333.1 - 0.00036 20.3 0.3 0.19 11.4 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_4 PF13462.6 ETS80333.1 - 0.0011 19.1 0.7 15 5.7 0.1 3.8 2 2 2 4 4 4 0 Thioredoxin Thioredoxin_3 PF13192.6 ETS80333.1 - 0.0018 18.3 0.0 1.3 9.1 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin domain Glutaredoxin PF00462.24 ETS80333.1 - 0.0031 17.7 0.2 4.9 7.5 0.0 3.0 2 1 0 2 2 2 2 Glutaredoxin DDE_Tnp_1_2 PF13586.6 ETS80333.1 - 0.19 12.1 0.0 11 6.5 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain Ribosomal_S14 PF00253.21 ETS80334.1 - 5.9e-14 51.6 3.6 6.3e-14 51.5 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 ETS80334.1 - 0.012 15.6 0.5 0.015 15.2 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) GTP_EFTU PF00009.27 ETS80335.1 - 9.4e-57 191.7 0.1 1.2e-56 191.3 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ETS80335.1 - 1.1e-25 90.1 0.0 2.6e-25 88.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ETS80335.1 - 1.2e-15 57.7 3.3 1.2e-15 57.7 3.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ETS80335.1 - 4.1e-05 23.6 0.0 7.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETS80335.1 - 0.00099 19.0 0.0 0.0027 17.6 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 ETS80335.1 - 0.024 14.2 0.2 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 ETS80335.1 - 0.065 13.0 0.1 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF4813 PF16072.5 ETS80337.1 - 0.53 9.9 21.7 0.14 11.8 13.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) Ribosomal_60s PF00428.19 ETS80337.1 - 4 8.1 22.4 5.1 7.7 9.4 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein NAD_kinase PF01513.21 ETS80338.1 - 6.3e-70 235.7 0.0 1e-69 235.0 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 ETS80338.1 - 0.19 11.4 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Fungal_trans PF04082.18 ETS80340.1 - 3.2e-16 59.2 0.0 5.1e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS80340.1 - 1.5e-08 34.6 8.3 2.4e-08 34.0 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ETS80341.1 - 2.9e-41 141.6 50.2 7e-41 140.3 50.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS80341.1 - 1.5e-16 59.9 16.7 2.6e-16 59.2 16.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMIE PF16038.5 ETS80342.1 - 0.24 11.3 0.9 0.43 10.4 0.9 1.3 1 0 0 1 1 1 0 TMIE protein Stb3 PF10330.9 ETS80343.1 - 0.0068 16.4 0.0 0.0089 16.0 0.0 1.2 1 0 0 1 1 1 1 Putative Sin3 binding protein Zn_clus PF00172.18 ETS80344.1 - 0.00012 22.1 10.5 0.00012 22.1 10.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 ETS80344.1 - 0.015 13.8 0.5 0.055 11.9 0.3 2.0 2 1 0 2 2 2 0 Centromere DNA-binding protein complex CBF3 subunit B adh_short PF00106.25 ETS80345.1 - 7.5e-50 169.1 0.0 9.1e-50 168.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS80345.1 - 1.1e-35 123.2 0.0 1.4e-35 122.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS80345.1 - 1.9e-09 37.7 0.0 2.6e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ETS80345.1 - 0.019 15.2 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Eno-Rase_NADH_b PF12242.8 ETS80345.1 - 0.066 13.0 0.1 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2OG-FeII_Oxy PF03171.20 ETS80346.1 - 6.5e-14 52.2 0.0 1.2e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ETS80346.1 - 8.3e-14 52.4 0.0 1.3e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Sugar_tr PF00083.24 ETS80347.1 - 3.9e-44 151.3 12.5 9.8e-42 143.3 8.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ETS80347.1 - 1.3e-11 44.0 21.6 1.5e-05 24.1 2.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily IU_nuc_hydro PF01156.19 ETS80348.1 - 3.4e-48 164.8 0.0 4.9e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF1205 PF06722.12 ETS80349.1 - 0.11 12.7 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) TPT PF03151.16 ETS80352.1 - 9.5e-22 77.7 13.1 1.1e-21 77.5 13.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ETS80352.1 - 1e-05 25.8 22.3 0.00048 20.3 1.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ETS80352.1 - 0.069 12.3 16.2 0.11 11.7 16.2 1.3 1 1 0 1 1 1 0 UAA transporter family Sec10 PF07393.11 ETS80353.1 - 7.4e-166 553.6 0.0 9.3e-166 553.2 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 ETS80353.1 - 1.7e-08 34.2 0.0 5.7e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS80353.1 - 4e-06 26.5 0.0 9.7e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ETS80353.1 - 0.0048 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 F-box bZIP_2 PF07716.15 ETS80354.1 - 0.0096 16.0 10.0 0.023 14.8 10.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper SR-25 PF10500.9 ETS80354.1 - 0.094 12.3 31.5 0.17 11.5 31.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM199X PF15814.5 ETS80354.1 - 0.29 10.1 15.7 0.53 9.3 15.7 1.4 1 0 0 1 1 1 0 Protein family FAM199X bZIP_1 PF00170.21 ETS80354.1 - 0.33 11.1 9.3 0.64 10.2 9.3 1.4 1 0 0 1 1 1 0 bZIP transcription factor CDC45 PF02724.14 ETS80354.1 - 8.4 4.5 21.0 11 4.2 21.0 1.1 1 0 0 1 1 1 0 CDC45-like protein p450 PF00067.22 ETS80355.1 - 4e-67 226.9 0.0 5e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SMAP PF15477.6 ETS80356.1 - 6.2e-13 49.5 3.1 6.2e-13 49.5 3.1 3.9 2 1 0 2 2 2 1 Small acidic protein family Caldesmon PF02029.15 ETS80356.1 - 0.0035 16.2 38.7 0.0038 16.1 38.7 1.2 1 0 0 1 1 1 1 Caldesmon TFIIF_alpha PF05793.12 ETS80356.1 - 0.0046 15.6 51.7 0.0064 15.2 51.7 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 ETS80356.1 - 0.94 8.8 51.6 1.3 8.3 51.6 1.1 1 0 0 1 1 1 0 BUD22 LAP1C PF05609.12 ETS80356.1 - 1.5 7.8 26.9 2 7.4 26.9 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF572 PF04502.13 ETS80356.1 - 2.5 7.6 36.5 3.6 7.1 36.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) RAMP4 PF06624.12 ETS80357.1 - 9.3e-21 73.7 0.2 1e-20 73.5 0.2 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 T2SSF PF00482.23 ETS80357.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF5542 PF17696.1 ETS80357.1 - 6.1 7.0 8.9 27 5.0 8.9 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5542) HSF_DNA-bind PF00447.17 ETS80358.1 - 0.059 14.0 0.0 0.068 13.8 0.0 1.2 1 0 0 1 1 1 0 HSF-type DNA-binding Mid1 PF12929.7 ETS80359.1 - 9.4e-148 492.9 10.3 1.1e-147 492.6 10.3 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 ETS80359.1 - 0.003 18.1 7.2 0.11 13.2 3.7 2.7 2 1 0 2 2 2 2 Fz domain TB2_DP1_HVA22 PF03134.19 ETS80360.1 - 4.5e-27 93.8 10.2 4.5e-27 93.8 10.2 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Bestrophin PF01062.21 ETS80360.1 - 0.0032 16.9 2.3 0.0045 16.4 2.3 1.3 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Kei1 PF08552.11 ETS80360.1 - 0.037 13.9 3.9 0.39 10.6 1.4 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2231 PF09990.9 ETS80360.1 - 0.04 14.4 1.6 3.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) DUF4407 PF14362.6 ETS80360.1 - 0.19 11.0 0.2 1.2 8.4 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RFX_DNA_binding PF02257.15 ETS80361.1 - 3.8e-27 94.7 0.0 7.8e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain AA_kinase PF00696.28 ETS80362.1 - 3e-39 135.0 0.5 8.2e-39 133.6 0.0 1.9 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 ETS80362.1 - 7.2e-14 51.3 0.6 8.9e-08 31.8 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 ETS80362.1 - 2.3e-13 49.7 3.8 2.9e-09 36.6 0.2 2.7 2 0 0 2 2 2 2 ACT domain DUF3375 PF11855.8 ETS80362.1 - 0.0061 15.5 0.0 0.0092 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3375) Eisosome1 PF12757.7 ETS80364.1 - 4.9e-43 146.4 12.3 4.9e-43 146.4 12.3 3.9 3 1 1 4 4 4 1 Eisosome protein 1 Y_phosphatase3 PF13350.6 ETS80365.1 - 9.3e-47 159.9 0.0 1.4e-46 159.4 0.0 1.2 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 ETS80365.1 - 8.7e-06 25.4 0.0 2e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.14 ETS80365.1 - 0.0041 16.1 0.1 0.0096 14.9 0.0 1.5 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 ETS80365.1 - 0.005 16.4 0.0 0.0074 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 ETS80365.1 - 0.037 14.3 0.1 0.085 13.2 0.0 1.6 2 0 0 2 2 2 0 Rit1 DUSP-like domain DSPc PF00782.20 ETS80365.1 - 0.1 12.4 0.0 0.56 10.0 0.0 1.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Methyltransf_12 PF08242.12 ETS80366.1 - 5e-15 56.1 0.0 1.3e-14 54.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS80366.1 - 8e-15 55.3 0.0 1.8e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS80366.1 - 1.6e-10 41.1 0.0 2.6e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS80366.1 - 1.8e-10 41.3 0.0 4.1e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS80366.1 - 1.7e-07 30.8 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ETS80366.1 - 4.6e-07 29.8 0.0 7.5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS80366.1 - 0.00035 20.2 0.0 0.00074 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 ETS80366.1 - 0.00088 20.3 0.0 0.0032 18.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Roc PF08477.13 ETS80366.1 - 0.041 14.1 0.9 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Methyltransf_32 PF13679.6 ETS80366.1 - 0.043 13.8 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 ETS80366.1 - 0.066 13.0 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase NNMT_PNMT_TEMT PF01234.17 ETS80366.1 - 0.11 11.6 0.0 4.3 6.5 0.0 2.3 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family DUF3298 PF11738.8 ETS80366.1 - 0.19 12.8 1.4 0.6 11.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) Polyketide_cyc PF03364.20 ETS80367.1 - 3.4e-23 82.3 0.0 9.6e-23 80.8 0.0 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF936 PF06075.12 ETS80368.1 - 0.54 9.1 37.9 0.8 8.6 37.9 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) TPR_11 PF13414.6 ETS80369.1 - 1.5e-09 37.4 0.0 0.00014 21.5 0.0 3.9 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.6 ETS80369.1 - 2e-07 31.3 5.7 0.006 17.3 0.0 5.2 2 1 4 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS80369.1 - 6.7e-07 29.7 0.6 0.00034 21.1 0.0 4.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 ETS80369.1 - 2e-05 24.3 3.3 0.00049 20.0 0.0 4.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 ETS80369.1 - 0.00017 22.1 5.4 0.0012 19.5 0.0 3.9 3 2 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 ETS80369.1 - 0.00034 20.8 0.0 4 8.1 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 ETS80369.1 - 0.002 17.8 0.0 0.012 15.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 ETS80369.1 - 0.012 15.8 0.4 0.034 14.3 0.4 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_20 PF14561.6 ETS80369.1 - 0.016 15.5 0.1 1.3 9.5 0.0 3.3 1 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 ETS80369.1 - 0.031 14.5 0.0 0.91 9.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ETS80369.1 - 0.08 13.6 0.2 22 5.9 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.10 ETS80369.1 - 0.17 10.9 0.5 0.22 10.5 0.1 1.4 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Adaptin_N PF01602.20 ETS80370.1 - 3.8e-84 283.1 0.0 5.3e-84 282.7 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ETS80370.1 - 9.1e-06 25.8 0.1 0.0027 17.7 0.0 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ETS80370.1 - 0.0087 16.6 0.8 1.4 9.5 0.0 3.8 4 0 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.6 ETS80370.1 - 0.021 15.2 0.2 0.38 11.2 0.0 2.9 2 1 0 2 2 2 0 HEAT repeats HEAT PF02985.22 ETS80370.1 - 0.022 15.0 0.0 4.3 7.9 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat Glyco_hydro_43 PF04616.14 ETS80371.1 - 2.1e-51 174.9 2.5 2.7e-51 174.6 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 ETS80371.1 - 5.4e-39 133.3 0.2 1.2e-38 132.2 0.2 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 ETS80371.1 - 9.7e-10 38.6 0.1 1.9e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 ETS80371.1 - 0.0015 18.2 1.6 0.0029 17.2 1.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_3 PF00933.21 ETS80372.1 - 2.6e-35 122.3 0.0 3.7e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 ETS80372.1 - 4.6e-33 114.9 0.0 7.4e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ETS80372.1 - 7.6e-05 22.7 0.0 0.00025 21.1 0.0 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain Frag1 PF10277.9 ETS80373.1 - 1.2e-42 145.9 17.0 1.4e-42 145.7 17.0 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Rft-1 PF04506.13 ETS80373.1 - 0.0025 16.6 0.9 0.0037 16.1 0.9 1.2 1 0 0 1 1 1 1 Rft protein DUF998 PF06197.13 ETS80373.1 - 0.0032 17.1 7.4 0.0032 17.1 7.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF998) DUF1461 PF07314.11 ETS80373.1 - 0.027 14.4 9.1 0.42 10.5 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1461) DUF2070 PF09843.9 ETS80373.1 - 0.41 8.9 6.5 0.44 8.8 6.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Pkinase PF00069.25 ETS80374.1 - 6.2e-65 219.2 0.0 7.6e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS80374.1 - 3e-34 118.5 0.0 4.3e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS80374.1 - 0.0013 18.1 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ETS80374.1 - 0.049 12.6 0.0 2.3 7.1 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain IGR PF09597.10 ETS80375.1 - 2.8e-24 85.0 0.1 5.1e-24 84.1 0.1 1.5 1 0 0 1 1 1 1 IGR protein motif SNF2_N PF00176.23 ETS80376.1 - 8.7e-59 199.0 0.0 1.8e-58 197.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 ETS80376.1 - 2.6e-09 36.8 11.1 5.8e-09 35.7 11.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ETS80376.1 - 4e-08 33.5 11.4 7.8e-08 32.5 11.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 ETS80376.1 - 7.1e-08 32.2 8.5 1.5e-07 31.2 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ETS80376.1 - 1.4e-07 31.2 10.5 3.1e-07 30.2 10.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ETS80376.1 - 1.3e-05 25.0 9.1 2.6e-05 24.1 9.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ETS80376.1 - 4.8e-05 23.6 8.3 0.00015 22.0 8.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 ETS80376.1 - 0.00014 21.7 12.5 0.00029 20.6 12.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 ETS80376.1 - 0.00027 20.9 10.8 0.00065 19.7 10.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Helicase_C PF00271.31 ETS80376.1 - 0.0016 18.8 0.0 0.0057 17.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.6 ETS80376.1 - 0.028 14.6 10.4 0.055 13.6 10.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 ETS80376.1 - 0.032 14.3 4.4 0.069 13.2 4.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 ETS80376.1 - 0.05 13.4 8.0 0.2 11.5 3.8 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain SRP54_N PF02881.19 ETS80376.1 - 0.087 13.1 0.0 0.41 10.9 0.0 2.2 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain Cytochrom_B562 PF07361.11 ETS80376.1 - 0.14 12.9 2.0 26 5.5 0.0 3.9 3 0 0 3 3 3 0 Cytochrome b562 Mob_synth_C PF06463.13 ETS80376.1 - 0.17 11.8 1.9 0.65 9.9 1.9 2.0 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-RING_6 PF14835.6 ETS80376.1 - 0.44 10.5 4.9 1.1 9.2 4.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.7 ETS80376.1 - 0.98 9.5 7.7 3 7.9 7.7 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-P11 PF03854.14 ETS80376.1 - 9.8 5.9 11.0 2.7 7.7 6.9 2.2 2 1 0 2 2 1 0 P-11 zinc finger ABC_membrane PF00664.23 ETS80377.1 - 6.5e-57 193.3 35.5 8.1e-35 120.8 19.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ETS80377.1 - 2.4e-47 160.9 0.0 2.1e-27 96.3 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 ETS80377.1 - 1.3e-05 25.7 0.0 0.1 13.0 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 ETS80377.1 - 3.8e-05 23.7 1.4 0.052 13.6 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 ETS80377.1 - 3.9e-05 23.2 2.0 0.12 11.8 0.5 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 ETS80377.1 - 5.7e-05 22.5 0.0 0.0053 16.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin RsgA_GTPase PF03193.16 ETS80377.1 - 0.00012 22.1 0.7 0.059 13.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ETS80377.1 - 0.00042 20.0 1.1 0.88 9.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 ETS80377.1 - 0.0005 20.0 0.0 0.6 9.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 ETS80377.1 - 0.0023 17.7 2.3 0.76 9.5 0.1 2.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 ETS80377.1 - 0.0087 16.3 1.4 7.9 6.8 0.1 3.4 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 ETS80377.1 - 0.02 13.8 0.6 2 7.3 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.23 ETS80377.1 - 0.039 14.0 3.6 0.56 10.3 0.4 2.8 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 ETS80377.1 - 0.044 14.0 0.1 7.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 ETS80377.1 - 0.048 13.4 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 ETS80377.1 - 0.068 12.7 0.5 2.9 7.4 0.2 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region SRP54 PF00448.22 ETS80377.1 - 0.085 12.5 0.3 1.2 8.7 0.0 2.7 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Ploopntkinase3 PF18751.1 ETS80377.1 - 0.12 12.3 0.2 15 5.4 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 NACHT PF05729.12 ETS80377.1 - 0.14 12.1 1.0 0.79 9.6 0.1 2.2 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.17 ETS80377.1 - 0.15 12.1 8.5 0.14 12.2 0.4 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_15 PF13175.6 ETS80377.1 - 0.22 11.2 0.4 8.9 5.9 0.1 2.8 3 0 0 3 3 3 0 AAA ATPase domain cobW PF02492.19 ETS80377.1 - 0.3 10.6 2.3 0.92 9.1 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 ETS80377.1 - 0.32 11.5 12.7 0.7 10.4 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 ETS80377.1 - 0.41 10.9 0.0 0.41 10.9 0.0 2.8 4 0 0 4 4 3 0 AAA domain MeaB PF03308.16 ETS80377.1 - 0.55 9.2 6.8 1.7 7.6 0.1 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB EMC3_TMCO1 PF01956.16 ETS80377.1 - 1.7 8.4 5.7 7.1 6.3 5.7 2.1 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Fcf1 PF04900.12 ETS80379.1 - 1.7e-33 115.0 0.1 3.2e-33 114.1 0.1 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 ETS80379.1 - 8.1e-12 45.5 0.7 2.4e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 PIN like domain N-SET PF11764.8 ETS80380.1 - 3.6e-51 173.7 2.4 3.6e-51 173.7 2.4 3.8 5 0 0 5 5 5 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 ETS80380.1 - 9.4e-26 89.2 0.6 2.9e-25 87.7 0.1 2.2 3 0 0 3 3 3 1 Histone lysine methyltransferase SET associated SET PF00856.28 ETS80380.1 - 6.4e-20 72.2 0.2 6.4e-20 72.2 0.2 4.2 4 2 0 4 4 4 1 SET domain Nup35_RRM_2 PF14605.6 ETS80380.1 - 0.16 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Tropomyosin_1 PF12718.7 ETS80382.1 - 4.4e-52 176.0 31.5 5.5e-52 175.7 31.5 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 ETS80382.1 - 6.5e-08 32.2 30.0 2.5e-05 23.8 5.6 3.0 1 1 2 3 3 3 3 Tropomyosin DUF724 PF05266.14 ETS80382.1 - 0.00012 21.9 19.9 0.023 14.6 7.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF724) BRE1 PF08647.11 ETS80382.1 - 0.00012 22.0 27.0 0.11 12.5 9.8 2.6 1 1 1 2 2 2 2 BRE1 E3 ubiquitin ligase GAS PF13851.6 ETS80382.1 - 0.00032 20.1 30.5 0.016 14.5 18.7 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding MAD PF05557.13 ETS80382.1 - 0.00044 18.7 25.4 0.0016 16.9 11.6 2.0 1 1 1 2 2 2 2 Mitotic checkpoint protein DUF4200 PF13863.6 ETS80382.1 - 0.00061 20.2 29.4 0.042 14.3 15.2 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) ATG16 PF08614.11 ETS80382.1 - 0.00061 20.1 32.6 0.44 10.8 18.8 2.3 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 ETS80382.1 - 0.00063 19.5 32.1 0.1 12.3 18.6 2.3 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease Taxilin PF09728.9 ETS80382.1 - 0.00083 18.6 25.2 0.022 14.0 12.9 2.1 1 1 1 2 2 2 2 Myosin-like coiled-coil protein Spc7 PF08317.11 ETS80382.1 - 0.0012 17.8 30.6 0.014 14.3 16.6 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein KLRAQ PF10205.9 ETS80382.1 - 0.0021 18.2 23.0 0.02 15.1 7.0 3.0 1 1 2 3 3 3 2 Predicted coiled-coil domain-containing protein HrpB7 PF09486.10 ETS80382.1 - 0.0069 16.8 17.0 0.41 11.0 13.4 2.8 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB7) Uso1_p115_C PF04871.13 ETS80382.1 - 0.0069 16.8 32.4 0.013 15.8 13.0 2.7 1 1 2 3 3 3 2 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip PF10473.9 ETS80382.1 - 0.0069 16.4 31.6 0.0084 16.1 5.5 2.6 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 ETS80382.1 - 0.0079 16.2 6.1 0.0079 16.2 6.1 2.2 1 1 1 2 2 2 1 Laminin Domain II APG6_N PF17675.1 ETS80382.1 - 0.0082 16.7 40.0 0.038 14.5 24.7 2.1 1 1 1 2 2 2 2 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 ETS80382.1 - 0.009 16.2 19.3 0.009 16.2 19.3 2.1 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 HMMR_N PF15905.5 ETS80382.1 - 0.0091 15.5 27.7 0.012 15.1 27.7 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal BLOC1_2 PF10046.9 ETS80382.1 - 0.011 16.0 22.2 0.33 11.3 1.4 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_TATA_bd PF12325.8 ETS80382.1 - 0.011 15.9 26.5 0.22 11.8 16.4 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 ETS80382.1 - 0.012 15.7 31.0 0.072 13.2 8.3 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding SHE3 PF17078.5 ETS80382.1 - 0.014 15.1 22.1 0.037 13.7 6.2 2.5 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 FlaC_arch PF05377.11 ETS80382.1 - 0.018 15.5 17.1 0.078 13.4 3.1 4.1 1 1 4 5 5 5 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 ETS80382.1 - 0.02 15.4 13.0 0.91 10.0 0.2 3.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.8 ETS80382.1 - 0.023 14.0 26.5 0.23 10.8 14.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) KELK PF15796.5 ETS80382.1 - 0.045 14.2 28.3 0.19 12.2 3.8 3.4 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CALCOCO1 PF07888.11 ETS80382.1 - 0.054 12.4 28.4 0.17 10.7 10.6 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1664 PF07889.12 ETS80382.1 - 0.078 13.0 13.5 0.11 12.5 2.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4201 PF13870.6 ETS80382.1 - 0.08 12.7 23.5 1.2 8.9 7.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) MIS13 PF08202.11 ETS80382.1 - 0.085 12.1 21.0 1.4 8.1 6.2 2.2 1 1 1 2 2 2 0 Mis12-Mtw1 protein family bZIP_1 PF00170.21 ETS80382.1 - 0.089 12.9 30.6 0.93 9.6 3.9 4.7 1 1 3 4 4 4 0 bZIP transcription factor TMF_DNA_bd PF12329.8 ETS80382.1 - 0.093 12.7 35.7 0.13 12.3 15.1 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 ETS80382.1 - 0.1 13.1 25.7 0.26 11.7 25.7 1.6 1 1 0 1 1 1 0 Fez1 Rab5-bind PF09311.11 ETS80382.1 - 0.1 12.0 23.1 0.03 13.7 10.1 2.1 1 1 1 2 2 2 0 Rabaptin-like protein KASH_CCD PF14662.6 ETS80382.1 - 0.11 12.4 29.7 1.1 9.1 13.3 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4686 PF15742.5 ETS80382.1 - 0.11 11.6 28.7 0.16 11.1 28.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) TPR_MLP1_2 PF07926.12 ETS80382.1 - 0.13 12.3 36.2 0.24 11.5 10.5 2.7 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein WXG100 PF06013.12 ETS80382.1 - 0.14 12.4 15.5 1.5 9.1 3.3 3.4 2 1 1 3 3 3 0 Proteins of 100 residues with WXG TolA_bind_tri PF16331.5 ETS80382.1 - 0.15 12.1 0.6 0.15 12.1 0.6 3.4 2 1 1 3 3 3 0 TolA binding protein trimerisation XhlA PF10779.9 ETS80382.1 - 0.16 12.2 25.0 1.5 9.0 0.6 4.1 1 1 2 4 4 4 0 Haemolysin XhlA ERM PF00769.19 ETS80382.1 - 0.21 11.4 33.5 0.087 12.6 18.4 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CEP63 PF17045.5 ETS80382.1 - 0.22 11.4 24.3 0.28 11.1 24.3 1.1 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Cep57_CLD_2 PF14197.6 ETS80382.1 - 0.28 11.3 32.0 0.2 11.8 6.3 4.1 2 2 3 5 5 5 0 Centrosome localisation domain of PPC89 Dynamitin PF04912.14 ETS80382.1 - 0.35 10.1 26.6 0.25 10.6 1.9 2.9 1 1 2 3 3 3 0 Dynamitin HHV-5_US34A PF17087.5 ETS80382.1 - 0.37 11.0 0.2 0.37 11.0 0.2 2.1 2 1 1 3 3 1 0 Herpesvirus US34A protein family ZapB PF06005.12 ETS80382.1 - 0.4 11.2 41.9 1.4 9.4 2.0 4.4 1 1 2 3 3 2 0 Cell division protein ZapB EzrA PF06160.12 ETS80382.1 - 0.4 8.8 21.3 2.6 6.1 12.7 1.9 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA CLZ PF16526.5 ETS80382.1 - 0.41 11.0 25.5 3 8.3 4.1 3.9 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SOGA PF11365.8 ETS80382.1 - 0.45 11.7 23.5 0.6 11.3 11.5 2.7 1 1 1 2 2 2 0 Protein SOGA DUF3584 PF12128.8 ETS80382.1 - 0.45 8.0 27.7 1.5 6.2 27.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) HOOK PF05622.12 ETS80382.1 - 0.51 8.4 27.6 1.4 7.0 27.6 1.7 1 1 0 1 1 1 0 HOOK protein Fmp27_WPPW PF10359.9 ETS80382.1 - 0.51 9.1 21.7 0.066 12.0 9.2 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF2730 PF10805.8 ETS80382.1 - 0.52 10.4 12.6 0.23 11.6 1.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) UPF0242 PF06785.11 ETS80382.1 - 0.53 10.4 30.3 1.7 8.7 8.9 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF5082 PF16888.5 ETS80382.1 - 0.53 10.6 20.2 0.99 9.7 8.7 3.1 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) HAP1_N PF04849.13 ETS80382.1 - 0.54 9.4 30.5 1.8 7.7 30.5 2.2 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Cortex-I_coil PF09304.10 ETS80382.1 - 0.62 10.3 22.9 1.3 9.3 7.4 3.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil HMMR_C PF15908.5 ETS80382.1 - 0.75 10.0 18.4 0.1 12.9 3.4 2.7 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Syntaxin-6_N PF09177.11 ETS80382.1 - 0.89 10.1 18.1 8.6 7.0 6.9 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ISG65-75 PF11727.8 ETS80382.1 - 0.96 8.6 16.4 0.42 9.8 9.5 2.3 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF4407 PF14362.6 ETS80382.1 - 1.1 8.6 23.1 0.89 8.9 7.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Sec34 PF04136.15 ETS80382.1 - 1.2 9.0 15.7 0.21 11.5 3.9 2.2 2 0 0 2 2 2 0 Sec34-like family CENP-H PF05837.12 ETS80382.1 - 1.2 9.5 26.1 3.1 8.3 0.5 2.9 1 1 2 3 3 3 0 Centromere protein H (CENP-H) PI3K_P85_iSH2 PF16454.5 ETS80382.1 - 1.4 8.5 26.3 1.2 8.7 8.4 3.0 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain YabA PF06156.13 ETS80382.1 - 1.6 9.4 23.3 16 6.2 0.9 3.0 1 1 1 2 2 2 0 Initiation control protein YabA Atg14 PF10186.9 ETS80382.1 - 1.9 7.5 22.1 1.7 7.6 12.2 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 ETS80382.1 - 2.3 7.5 20.5 1.7e+02 1.4 20.5 2.0 1 1 0 1 1 1 0 FAM76 protein Cep57_MT_bd PF06657.13 ETS80382.1 - 2.5 8.6 21.5 1.4 9.5 3.2 3.6 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 AAA_13 PF13166.6 ETS80382.1 - 3.2 6.3 21.3 7.4 5.1 21.3 1.5 1 1 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 ETS80382.1 - 3.2 5.5 18.9 0.38 8.6 8.1 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family IFT46_B_C PF12317.8 ETS80382.1 - 3.3 7.4 8.0 1.1 9.0 4.9 1.5 1 1 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal DUF812 PF05667.11 ETS80382.1 - 3.8 6.3 25.1 5.7 5.7 25.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ABC_tran_CTD PF16326.5 ETS80382.1 - 3.9 7.8 32.8 20 5.6 5.2 3.6 1 1 2 3 3 3 0 ABC transporter C-terminal domain HemX PF04375.14 ETS80382.1 - 4.2 6.6 26.1 6.4 6.0 9.1 2.2 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DHR10 PF18595.1 ETS80382.1 - 4.9 7.2 37.0 1.1 9.4 10.7 3.3 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain TMPIT PF07851.13 ETS80382.1 - 5.1 6.3 19.3 4.9 6.3 11.8 2.0 1 1 1 2 2 2 0 TMPIT-like protein FapA PF03961.13 ETS80382.1 - 5.1 5.6 23.3 0.21 10.2 9.6 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Prefoldin_2 PF01920.20 ETS80382.1 - 5.6 7.0 32.0 0.42 10.6 2.4 3.9 2 1 2 4 4 4 0 Prefoldin subunit FUSC PF04632.12 ETS80382.1 - 5.6 5.4 8.7 7.4 5.0 8.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family HAUS-augmin3 PF14932.6 ETS80382.1 - 5.7 6.4 29.8 2.7 7.5 18.0 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 ETS80382.1 - 5.8 7.6 26.6 22 5.8 2.2 4.0 1 1 4 5 5 5 0 SlyX DivIC PF04977.15 ETS80382.1 - 6.2 6.7 36.0 0.55 10.0 4.8 4.5 1 1 3 4 4 3 0 Septum formation initiator Fungal_TACC PF12709.7 ETS80382.1 - 6.5 7.3 25.0 0.81 10.2 2.6 3.6 1 1 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins Phage_GPO PF05929.11 ETS80382.1 - 6.7 6.3 20.5 4.1 7.0 8.5 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4472 PF14739.6 ETS80382.1 - 6.7 7.5 25.1 27 5.6 11.3 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Ax_dynein_light PF10211.9 ETS80382.1 - 8.1 6.3 28.8 2.1 8.3 4.9 3.4 1 1 1 2 2 1 0 Axonemal dynein light chain DUF4972 PF16342.5 ETS80382.1 - 8.2 6.1 10.9 4.1 7.1 5.2 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4972) CHDCT2 PF08074.11 ETS80382.1 - 8.5 6.5 11.4 1 9.5 4.6 2.1 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Seryl_tRNA_N PF02403.22 ETS80382.1 - 8.5 6.7 27.6 5.3 7.3 1.4 3.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain GIT_CC PF16559.5 ETS80382.1 - 8.6 6.3 25.3 3.5 7.6 2.0 4.7 1 1 4 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor Occludin_ELL PF07303.13 ETS80382.1 - 9.3 7.1 17.8 5.4 7.8 5.3 3.1 1 1 2 3 3 3 0 Occludin homology domain KxDL PF10241.9 ETS80382.1 - 9.4 6.6 16.1 4.3 7.7 4.4 3.3 1 1 2 3 3 3 0 Uncharacterized conserved protein MPS2 PF17060.5 ETS80382.1 - 9.6 5.3 16.5 31 3.7 16.5 1.8 1 1 0 1 1 1 0 Monopolar spindle protein 2 PRKG1_interact PF15898.5 ETS80382.1 - 9.9 7.1 26.8 4.4 8.3 13.5 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Nop25 PF09805.9 ETS80383.1 - 9.4e-42 142.7 16.0 9.4e-42 142.7 16.0 2.2 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) F_bP_aldolase PF01116.20 ETS80383.1 - 0.015 14.8 0.3 0.026 14.0 0.3 1.4 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II EIIBC-GUT_N PF03612.14 ETS80383.1 - 0.72 9.6 13.8 0.52 10.0 4.2 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus ATP-synt_S1 PF05827.12 ETS80384.1 - 4e-05 23.5 0.0 0.00012 21.9 0.0 1.7 2 0 0 2 2 2 1 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF829 PF05705.14 ETS80384.1 - 0.08 12.8 0.1 2.3 8.1 0.0 2.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF829) FAD-oxidase_C PF02913.19 ETS80384.1 - 0.097 12.3 0.2 0.12 12.0 0.2 1.1 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Trm112p PF03966.16 ETS80385.1 - 6.6e-17 61.8 0.1 8.6e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.6 ETS80385.1 - 0.023 15.2 0.4 0.038 14.5 0.4 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-BED PF02892.15 ETS80385.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 BED zinc finger Pro_isomerase PF00160.21 ETS80386.1 - 6.8e-49 166.2 0.2 9.2e-49 165.7 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.22 ETS80387.1 - 3.4e-14 53.4 0.4 2.4e-11 44.1 1.6 2.0 1 1 1 2 2 2 2 Ribosomal protein S13/S18 Peptidase_M19 PF01244.21 ETS80388.1 - 5.3e-102 341.3 0.0 6.1e-102 341.0 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) RhoGAP PF00620.27 ETS80389.1 - 1.7e-16 60.4 0.3 4.2e-16 59.1 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 ETS80389.1 - 8.5e-13 48.2 0.0 1.8e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 ETS80389.1 - 1.9e-10 40.8 0.0 6.9e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SNF2_N PF00176.23 ETS80390.1 - 2.6e-74 250.0 0.3 3.8e-74 249.5 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS80390.1 - 1.3e-13 51.2 0.5 1.2e-12 48.1 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS80390.1 - 2.5e-06 27.6 0.0 7.9e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ETS80390.1 - 1.7e-05 24.7 0.0 6.6e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Pkinase_Tyr PF07714.17 ETS80391.1 - 1.8e-19 70.1 0.0 3.7e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ETS80391.1 - 2.1e-19 70.0 0.0 7e-19 68.2 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain NACHT PF05729.12 ETS80391.1 - 3.9e-09 36.7 1.0 1.9e-08 34.4 0.0 2.8 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 ETS80391.1 - 0.00015 22.2 0.8 0.0014 19.0 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ETS80391.1 - 0.00024 21.4 0.2 0.0012 19.2 0.0 2.3 2 0 0 2 2 1 1 AAA domain Ank_4 PF13637.6 ETS80391.1 - 0.00042 20.8 0.1 0.0028 18.2 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 ETS80391.1 - 0.00045 20.5 1.3 0.0029 18.0 0.3 3.0 3 0 0 3 3 2 1 Ankyrin repeat Ank_5 PF13857.6 ETS80391.1 - 0.0069 16.7 0.2 0.025 14.9 0.2 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS80391.1 - 0.017 15.7 0.0 0.1 13.2 0.1 2.2 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) AAA_18 PF13238.6 ETS80391.1 - 0.026 15.0 0.0 0.3 11.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ETS80391.1 - 0.029 13.7 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.22 ETS80391.1 - 0.049 12.8 0.0 0.26 10.5 0.0 2.3 1 1 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 ETS80391.1 - 0.07 13.2 0.1 3 7.9 0.0 3.2 2 1 0 2 2 2 0 AAA domain Goodbye PF17109.5 ETS80391.1 - 0.12 12.8 0.0 1.1 9.7 0.0 2.8 3 0 0 3 3 2 0 fungal STAND N-terminal Goodbye domain AAA PF00004.29 ETS80391.1 - 0.14 12.6 0.5 1.3 9.4 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ETS80391.1 - 0.16 11.7 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain HD PF01966.22 ETS80392.1 - 0.086 13.1 0.1 0.16 12.2 0.1 1.5 2 0 0 2 2 2 0 HD domain HET PF06985.11 ETS80393.1 - 5.1e-34 117.7 3.4 9e-34 116.9 3.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SLAC1 PF03595.17 ETS80394.1 - 8.9e-82 274.9 44.4 1e-81 274.7 44.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Glyco_hydro_cc PF11790.8 ETS80395.1 - 4.4e-56 190.1 0.0 5.3e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Spc7 PF08317.11 ETS80396.1 - 4.6e-05 22.4 9.0 4.6e-05 22.4 9.0 4.1 3 1 1 4 4 4 2 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 ETS80396.1 - 0.00063 20.3 45.1 0.00064 20.3 6.9 5.6 4 3 2 6 6 6 3 Clathrin-binding domain of Huntingtin-interacting protein 1 TMF_TATA_bd PF12325.8 ETS80396.1 - 0.0083 16.3 5.2 0.0083 16.3 5.2 5.0 4 1 1 5 5 5 2 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 ETS80396.1 - 0.019 15.4 31.4 0.18 12.2 8.7 4.3 3 1 1 4 4 4 0 Fez1 TMF_DNA_bd PF12329.8 ETS80396.1 - 0.033 14.2 36.5 1.1 9.3 0.0 6.5 3 2 3 6 6 6 0 TATA element modulatory factor 1 DNA binding LUC7 PF03194.15 ETS80396.1 - 0.11 12.1 10.1 0.11 12.1 0.8 2.5 2 0 0 2 2 2 0 LUC7 N_terminus DUF4279 PF14106.6 ETS80396.1 - 0.2 11.9 2.0 0.93 9.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4279) TPD52 PF04201.15 ETS80396.1 - 0.29 10.8 13.6 0.29 10.7 0.1 3.9 4 0 0 4 4 4 0 Tumour protein D52 family DUF1664 PF07889.12 ETS80396.1 - 0.37 10.8 18.5 0.39 10.8 0.1 5.4 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Spc29 PF17082.5 ETS80396.1 - 0.79 9.5 15.4 0.028 14.3 1.3 3.4 3 1 0 3 3 3 0 Spindle Pole Component 29 AAA_13 PF13166.6 ETS80396.1 - 0.86 8.2 24.1 0.29 9.7 7.3 3.9 3 1 1 4 4 4 0 AAA domain Golgin_A5 PF09787.9 ETS80396.1 - 0.9 8.9 32.4 0.21 11.0 7.7 4.3 3 1 1 4 4 4 0 Golgin subfamily A member 5 Tup_N PF08581.10 ETS80396.1 - 1.1 9.6 22.1 0.27 11.5 1.0 5.4 4 1 1 5 5 5 0 Tup N-terminal E2R135 PF11570.8 ETS80396.1 - 1.7 8.9 8.2 2 8.7 0.1 3.5 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 FUSC PF04632.12 ETS80396.1 - 1.9 6.9 30.5 0.0088 14.6 5.1 3.6 2 1 1 4 4 4 0 Fusaric acid resistance protein family Filament PF00038.21 ETS80396.1 - 2.6 7.6 34.4 0.59 9.7 6.6 5.0 3 1 2 5 5 5 0 Intermediate filament protein FlaC_arch PF05377.11 ETS80396.1 - 2.9 8.4 19.5 4 7.9 0.1 7.0 4 4 4 8 8 8 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 ETS80396.1 - 3 7.1 33.6 0.83 8.9 4.1 4.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) FlxA PF14282.6 ETS80396.1 - 4.6 7.3 27.7 0.14 12.2 4.5 3.5 4 0 0 4 4 3 0 FlxA-like protein ApoLp-III PF07464.11 ETS80396.1 - 8.3 6.5 10.0 0.42 10.7 2.5 2.6 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) BLOC1_2 PF10046.9 ETS80396.1 - 8.4 6.8 17.5 14 6.1 0.0 4.7 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RIO1 PF01163.22 ETS80397.1 - 4e-67 225.5 0.0 4e-67 225.5 0.0 2.0 3 0 0 3 3 3 1 RIO1 family APH PF01636.23 ETS80397.1 - 0.0091 15.9 0.3 0.39 10.6 0.2 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ETS80397.1 - 0.02 14.3 0.3 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MARVEL PF01284.23 ETS80398.1 - 7.3e-10 39.0 18.1 6.2e-08 32.8 18.1 2.1 1 1 0 1 1 1 1 Membrane-associating domain DUF588 PF04535.12 ETS80398.1 - 0.0027 17.5 1.5 0.0027 17.5 1.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF588) Peptidase_M56 PF05569.11 ETS80398.1 - 0.013 14.7 0.6 0.018 14.2 0.6 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF1761 PF08570.10 ETS80398.1 - 0.017 15.4 4.5 0.017 15.4 4.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) Metallophos PF00149.28 ETS80399.1 - 1.7e-15 58.1 0.3 5.5e-15 56.4 0.2 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ETS80399.1 - 3.8e-05 23.9 0.1 0.0018 18.5 0.0 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Ank_2 PF12796.7 ETS80400.1 - 2.2e-13 50.6 0.2 7.7e-06 26.4 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS80400.1 - 2.1e-08 34.5 0.5 0.016 15.7 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS80400.1 - 3.3e-05 23.9 0.2 13 6.7 0.0 5.6 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 ETS80400.1 - 0.0013 19.0 0.1 0.033 14.5 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS80400.1 - 0.059 13.8 0.1 4.5 7.9 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeat SMBP PF16785.5 ETS80400.1 - 0.13 12.5 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Small metal-binding protein HET PF06985.11 ETS80401.1 - 4.6e-08 33.5 0.7 4.6e-08 33.5 0.7 2.8 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 ETS80401.1 - 4.3e-06 26.7 0.0 9.8e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 ETS80401.1 - 0.016 15.6 0.0 0.061 13.8 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS80401.1 - 0.026 14.8 0.2 0.13 12.5 0.0 2.3 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 ETS80401.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 ETS80401.1 - 0.12 11.7 0.0 0.34 10.2 0.0 1.7 1 0 0 1 1 1 0 KaiC Ank_2 PF12796.7 ETS80402.1 - 7.2e-37 125.9 17.3 4.1e-19 69.0 2.1 3.9 2 1 2 4 4 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS80402.1 - 3.3e-27 94.5 1.7 6.3e-11 42.6 0.1 4.3 4 0 0 4 4 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ETS80402.1 - 3.9e-27 93.5 7.4 6.8e-06 26.3 0.0 5.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 ETS80402.1 - 3.5e-24 82.2 4.0 2.2e-05 24.5 0.0 6.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 ETS80402.1 - 2.6e-14 53.1 7.0 9.8e-06 25.8 0.6 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) NACHT PF05729.12 ETS80402.1 - 4.4e-09 36.5 0.4 1.2e-08 35.1 0.2 1.9 2 0 0 2 2 2 1 NACHT domain Helo_like_N PF17111.5 ETS80402.1 - 3.3e-06 26.6 0.3 1.2e-05 24.8 0.1 2.1 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 ETS80402.1 - 1.5e-05 25.4 0.4 1.5e-05 25.4 0.4 3.0 3 0 0 3 3 3 1 AAA ATPase domain HrpJ PF07201.11 ETS80402.1 - 0.0085 16.4 2.7 0.025 14.9 0.1 2.9 2 0 0 2 2 2 1 HrpJ-like domain AAA_22 PF13401.6 ETS80402.1 - 0.011 16.1 0.1 0.083 13.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Phage_HK97_TLTM PF06120.11 ETS80402.1 - 0.012 14.8 0.8 0.13 11.5 0.2 2.2 2 0 0 2 2 2 0 Tail length tape measure protein TMF_TATA_bd PF12325.8 ETS80402.1 - 0.023 14.9 5.2 0.052 13.8 2.5 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding NB-ARC PF00931.22 ETS80402.1 - 0.026 13.7 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 ETS80402.1 - 0.051 13.6 0.0 0.46 10.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain NPV_P10 PF05531.12 ETS80402.1 - 0.089 13.3 2.4 3.7 8.1 0.1 3.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein VWA_3_C PF18571.1 ETS80402.1 - 0.37 10.7 12.8 12 5.9 0.2 5.3 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain SesA PF17107.5 ETS80402.1 - 1.3 9.3 8.7 0.36 11.0 0.6 3.6 4 1 1 5 5 5 0 N-terminal domain on NACHT_NTPase and P-loop NTPases V-SNARE PF05008.15 ETS80402.1 - 8.8 6.8 6.5 1.2 9.5 0.2 2.9 3 0 0 3 3 2 0 Vesicle transport v-SNARE protein N-terminus p450 PF00067.22 ETS80403.1 - 2.1e-30 105.9 0.0 1.9e-29 102.7 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS80404.1 - 5e-51 173.9 0.1 6.2e-51 173.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.15 ETS80405.1 - 2.3e-15 56.2 0.0 7.7e-15 54.5 0.0 1.6 1 1 0 1 1 1 1 Transferase family Mito_carr PF00153.27 ETS80406.1 - 3.4e-41 139.1 8.2 9.6e-18 63.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.18 ETS80407.1 - 2.5e-08 33.9 9.6 4.6e-08 33.1 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH_1 PF00378.20 ETS80408.1 - 3.8e-43 147.6 0.0 4.5e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ETS80408.1 - 1.3e-28 100.5 0.1 1.7e-28 100.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase p450 PF00067.22 ETS80409.1 - 4.8e-55 187.1 0.0 7.1e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Acyl-CoA_dh_1 PF00441.24 ETS80409.1 - 2.1e-30 105.9 1.7 2.1e-30 105.9 1.7 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ETS80409.1 - 2.3e-24 86.2 0.0 9e-24 84.3 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ETS80409.1 - 5.6e-22 77.8 0.2 1.1e-21 76.8 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ETS80409.1 - 7e-09 36.1 2.4 1.4e-08 35.1 2.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3829 PF12889.7 ETS80409.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) ADH_zinc_N PF00107.26 ETS80410.1 - 7.3e-09 35.7 0.2 3.1e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS80410.1 - 2.2e-07 30.7 0.0 4.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ETS80410.1 - 7.7e-06 27.0 0.0 2.2e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ETS80410.1 - 0.048 13.6 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase FSH1 PF03959.13 ETS80411.1 - 1.2e-32 113.3 0.0 1.4e-32 113.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 ETS80411.1 - 0.00022 21.1 0.2 0.00072 19.4 0.2 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase ketoacyl-synt PF00109.26 ETS80412.1 - 8.4e-75 251.6 0.0 1.5e-74 250.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 ETS80412.1 - 1.9e-58 198.3 0.0 3.3e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 ETS80412.1 - 2.8e-56 190.9 0.0 4.4e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 ETS80412.1 - 1.6e-48 165.0 0.0 4.7e-48 163.5 0.0 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 ETS80412.1 - 6.8e-41 140.8 0.0 1.6e-40 139.6 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ETS80412.1 - 5e-32 110.4 0.1 1.9e-31 108.5 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ETS80412.1 - 4.9e-20 72.1 0.0 1.5e-19 70.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ETS80412.1 - 2e-15 57.2 0.0 6.3e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 ETS80412.1 - 3.3e-14 53.0 0.3 1e-13 51.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS80412.1 - 6e-12 46.1 0.0 2.8e-11 44.0 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS80412.1 - 3.5e-10 40.4 0.0 9.7e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS80412.1 - 6.7e-10 39.0 0.0 1.9e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 ETS80412.1 - 7.8e-09 35.3 0.0 1.2e-07 31.4 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 ETS80412.1 - 1.8e-07 31.4 0.3 5.2e-07 29.9 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.9 ETS80412.1 - 5.3e-06 26.3 0.0 0.0001 22.1 0.0 2.3 2 0 0 2 2 2 1 Lysine methyltransferase Ubie_methyltran PF01209.18 ETS80412.1 - 0.00029 20.2 0.0 0.00059 19.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 ETS80412.1 - 0.00033 20.5 0.0 0.00089 19.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF938) MTS PF05175.14 ETS80412.1 - 0.0021 17.6 0.0 0.0059 16.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain Thiolase_N PF00108.23 ETS80412.1 - 0.003 17.0 0.1 0.0064 15.9 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain GHMP_kinases_N PF00288.26 ETS80412.1 - 0.14 12.5 0.8 0.47 10.7 0.8 2.0 1 0 0 1 1 1 0 GHMP kinases N terminal domain RrnaAD PF00398.20 ETS80412.1 - 0.16 11.0 0.0 0.43 9.6 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase ketoacyl-synt PF00109.26 ETS80413.1 - 7.5e-70 235.4 0.2 2e-69 234.0 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ETS80413.1 - 6.8e-60 202.0 1.9 1.4e-59 201.0 0.2 2.6 3 0 0 3 3 2 1 KR domain PS-DH PF14765.6 ETS80413.1 - 2e-50 171.8 0.0 4.1e-50 170.7 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ETS80413.1 - 4.8e-48 164.3 0.0 1.1e-47 163.1 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ETS80413.1 - 5.5e-37 126.4 0.9 1.7e-36 124.8 0.9 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ETS80413.1 - 1.1e-16 61.2 0.0 4.3e-16 59.4 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 ETS80413.1 - 6.3e-15 55.1 0.1 2.6e-14 53.1 0.1 2.1 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_12 PF08242.12 ETS80413.1 - 1.6e-13 51.2 0.0 6.6e-13 49.2 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 ETS80413.1 - 1.3e-09 38.0 0.0 3.5e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_23 PF13489.6 ETS80413.1 - 1.6e-09 37.8 0.0 4.9e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS80413.1 - 5.1e-09 36.7 0.1 6.7e-08 33.1 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS80413.1 - 8.1e-07 29.6 0.0 1.3e-05 25.7 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain ADH_zinc_N PF00107.26 ETS80413.1 - 1.7e-05 24.8 3.9 2.6e-05 24.2 0.0 3.3 4 0 0 4 4 3 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 ETS80413.1 - 3.4e-05 23.7 0.0 0.00013 21.8 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS80413.1 - 5.7e-05 22.6 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.25 ETS80413.1 - 0.00014 22.2 0.9 0.00043 20.6 0.9 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 ETS80413.1 - 0.00028 22.0 0.0 0.083 13.9 0.0 4.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Thiolase_N PF00108.23 ETS80413.1 - 0.0041 16.5 0.3 0.051 12.9 0.2 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 ETS80413.1 - 0.1 12.5 0.2 0.32 10.9 0.2 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Transferase PF02458.15 ETS80414.1 - 2.4e-09 36.4 0.0 3.4e-08 32.6 0.0 2.5 2 1 0 2 2 2 1 Transferase family adh_short PF00106.25 ETS80415.1 - 7.6e-28 97.3 0.4 9.4e-28 97.0 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS80415.1 - 2e-17 63.5 0.2 2.5e-17 63.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ETS80415.1 - 1.7e-05 24.5 0.1 0.015 14.8 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 ETS80415.1 - 0.00054 19.9 0.2 0.003 17.5 0.1 2.0 2 1 1 3 3 3 1 KR domain GDP_Man_Dehyd PF16363.5 ETS80415.1 - 0.0014 18.1 0.0 0.44 9.9 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 ETS80415.1 - 0.02 15.2 0.1 0.037 14.3 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_10 PF13460.6 ETS80415.1 - 0.026 14.4 0.4 0.069 13.0 0.4 1.7 1 1 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 ETS80416.1 - 1.5e-17 63.9 0.0 3e-17 62.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS80416.1 - 6e-13 48.4 0.0 9.6e-13 47.8 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ETS80416.1 - 1.2e-12 47.9 0.0 2.7e-12 46.8 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ETS80416.1 - 2.9e-12 46.9 0.0 4.7e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ETS80416.1 - 3.3e-09 36.3 0.0 7e-08 32.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ETS80416.1 - 4.2e-09 36.0 0.0 6.6e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ETS80416.1 - 2.2e-06 27.4 0.0 3.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 ETS80416.1 - 5.5e-05 22.7 0.0 0.00017 21.1 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ETS80416.1 - 0.00019 21.4 0.0 0.00069 19.6 0.0 1.8 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 ETS80416.1 - 0.0053 15.9 0.0 0.0081 15.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3HCDH_N PF02737.18 ETS80416.1 - 0.056 13.3 0.0 0.085 12.7 0.0 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cupin_2 PF07883.11 ETS80417.1 - 7.4e-07 28.8 0.1 1.1e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain FAD_binding_4 PF01565.23 ETS80418.1 - 3e-25 88.6 1.6 5.8e-25 87.6 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS80418.1 - 7.5e-07 29.2 0.1 1.7e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF4148 PF13663.6 ETS80418.1 - 0.1 12.8 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) DUF5372 PF17342.2 ETS80418.1 - 0.17 12.3 0.1 0.33 11.4 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5372) HTH_51 PF18558.1 ETS80419.1 - 8.1e-29 99.4 0.0 1.6e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Methyltransf_12 PF08242.12 ETS80419.1 - 1.8e-17 63.9 0.0 6.3e-17 62.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS80419.1 - 2.6e-14 53.4 0.0 4.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS80419.1 - 2.9e-10 40.1 0.0 4.5e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS80419.1 - 2e-09 38.0 0.0 4.5e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS80419.1 - 6.1e-08 33.2 0.0 2e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DREV PF05219.12 ETS80419.1 - 9.2e-06 24.9 0.0 2.3e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 DREV methyltransferase Ubie_methyltran PF01209.18 ETS80419.1 - 0.00052 19.4 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 ETS80419.1 - 0.005 16.5 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_28 PF02636.17 ETS80419.1 - 0.016 14.8 0.1 0.045 13.4 0.1 1.7 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_PK PF05891.12 ETS80419.1 - 0.024 14.2 0.0 0.055 13.0 0.0 1.5 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_33 PF10017.9 ETS80419.1 - 0.024 13.8 0.1 0.038 13.1 0.1 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_16 PF10294.9 ETS80419.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase p450 PF00067.22 ETS80420.1 - 1.4e-52 179.0 0.0 1.8e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 ETS80421.1 - 3e-36 124.7 2.7 3.9e-36 124.4 2.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS80421.1 - 2.6e-27 95.9 0.8 3.5e-27 95.5 0.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 ETS80421.1 - 1.9e-07 30.7 0.0 3.2e-06 26.7 0.0 2.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 ETS80421.1 - 0.0017 17.9 0.2 0.0032 17.0 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ETS80421.1 - 0.0022 18.2 0.2 0.0037 17.5 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 ETS80421.1 - 0.014 15.6 0.1 0.033 14.4 0.1 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NmrA PF05368.13 ETS80421.1 - 0.036 13.6 0.0 0.23 11.0 0.1 2.1 2 0 0 2 2 2 0 NmrA-like family Ank_2 PF12796.7 ETS80422.1 - 6.5e-33 113.2 9.7 1.1e-13 51.6 1.3 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS80422.1 - 2.2e-21 75.9 7.7 3.9e-10 40.1 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS80422.1 - 1.6e-18 66.5 0.5 6.4e-11 42.3 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS80422.1 - 3.3e-18 63.9 1.1 0.00015 21.9 0.1 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 ETS80422.1 - 2.9e-15 55.9 6.8 0.00024 21.4 0.3 4.4 4 0 0 4 4 4 3 Ankyrin repeat bZIP_1 PF00170.21 ETS80422.1 - 0.31 11.2 7.8 0.65 10.1 7.8 1.5 1 0 0 1 1 1 0 bZIP transcription factor FAD_binding_4 PF01565.23 ETS80423.1 - 3.1e-21 75.6 1.9 7.7e-21 74.3 1.9 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS80423.1 - 4e-11 42.8 1.0 1.5e-10 41.0 0.7 2.2 2 0 0 2 2 2 1 Berberine and berberine like Abhydrolase_6 PF12697.7 ETS80424.1 - 7.5e-14 52.9 0.2 1e-13 52.4 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS80424.1 - 1.5e-11 44.1 0.0 6.8e-11 41.9 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 ETS80424.1 - 6.4e-10 38.2 0.1 6e-05 21.9 0.1 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 ETS80424.1 - 9.3e-07 28.7 0.0 0.0019 17.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS80424.1 - 1.6e-06 27.7 0.0 0.0002 20.9 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ETS80424.1 - 3.6e-05 23.5 0.0 8e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1100 PF06500.11 ETS80424.1 - 0.0021 16.9 0.0 0.0029 16.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.18 ETS80424.1 - 0.18 11.3 0.0 1 8.8 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family ketoacyl-synt PF00109.26 ETS80425.1 - 1e-59 202.2 0.0 2.3e-59 201.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ETS80425.1 - 7.6e-54 182.3 2.0 1.2e-53 181.7 0.2 2.3 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.21 ETS80425.1 - 1.8e-44 152.6 0.0 2.8e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 ETS80425.1 - 8.6e-44 150.0 0.0 1.5e-43 149.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 ETS80425.1 - 1e-32 112.6 0.4 1e-31 109.4 0.4 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ETS80425.1 - 2.3e-18 66.7 0.0 8.1e-18 64.9 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 ETS80425.1 - 3.1e-18 67.1 0.0 1.5e-17 64.9 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ETS80425.1 - 6.8e-11 42.0 0.1 3.1e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 ETS80425.1 - 2e-10 40.7 0.0 6.6e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 ETS80425.1 - 2.5e-09 37.1 0.0 5.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 ETS80425.1 - 8.7e-08 32.0 0.2 2.1e-07 30.8 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 ETS80425.1 - 5.7e-07 29.8 1.3 1.1e-06 28.8 0.1 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site SAT PF16073.5 ETS80425.1 - 0.00011 22.0 0.0 0.0004 20.2 0.0 1.9 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis AAA_16 PF13191.6 ETS80425.1 - 0.03 14.7 0.0 1.4 9.3 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain p450 PF00067.22 ETS80426.1 - 7.1e-48 163.5 0.0 1e-47 163.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 ETS80428.1 - 2.8e-69 233.5 0.1 5.6e-69 232.5 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ETS80428.1 - 7.1e-61 205.3 0.1 1.2e-60 204.5 0.1 1.4 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.6 ETS80428.1 - 1.8e-19 71.1 0.0 5e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ETS80428.1 - 3.1e-14 53.1 0.3 8.5e-14 51.7 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 ETS80428.1 - 5.1e-13 48.9 0.2 1.1e-12 47.9 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.22 ETS80428.1 - 9.6e-11 41.7 0.0 2.9e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short_C2 PF13561.6 ETS80428.1 - 1.5e-07 31.2 0.0 3.3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 ETS80428.1 - 2.6e-05 24.1 0.6 9e-05 22.3 0.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Polysacc_synt_2 PF02719.15 ETS80428.1 - 0.00023 20.4 0.0 0.00039 19.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Thiolase_N PF00108.23 ETS80428.1 - 0.0019 17.6 0.4 0.0036 16.7 0.4 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.19 ETS80428.1 - 0.0082 15.2 0.0 0.023 13.7 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 ETS80428.1 - 0.095 13.0 0.2 0.24 11.6 0.0 1.8 2 0 0 2 2 1 0 Saccharopine dehydrogenase NADP binding domain ACP_syn_III PF08545.10 ETS80428.1 - 0.17 11.7 1.8 3.7 7.5 1.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PP-binding PF00550.25 ETS80429.1 - 0.13 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Phosphopantetheine attachment site NACHT PF05729.12 ETS80430.1 - 7.4e-16 58.5 0.0 2.1e-15 57.0 0.0 1.9 1 0 0 1 1 1 1 NACHT domain HEAT_2 PF13646.6 ETS80430.1 - 1.3e-13 51.1 13.3 5.1e-05 23.6 0.3 7.1 7 2 2 9 9 6 3 HEAT repeats NB-ARC PF00931.22 ETS80430.1 - 2.1e-06 27.1 0.0 8e-06 25.2 0.0 2.0 2 0 0 2 2 1 1 NB-ARC domain AAA_22 PF13401.6 ETS80430.1 - 3e-06 27.5 0.7 0.0028 17.9 0.0 4.1 4 0 0 4 4 3 1 AAA domain HEAT PF02985.22 ETS80430.1 - 8.6e-06 25.6 2.4 28 5.3 0.1 6.7 6 0 0 6 6 5 0 HEAT repeat DUF676 PF05057.14 ETS80430.1 - 1.5e-05 24.6 0.0 4.2e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_16 PF13191.6 ETS80430.1 - 0.00029 21.3 0.1 0.0027 18.1 0.0 2.7 2 0 0 2 2 1 1 AAA ATPase domain AAA PF00004.29 ETS80430.1 - 0.00056 20.3 0.8 0.15 12.5 0.0 3.9 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) PGAP1 PF07819.13 ETS80430.1 - 0.00086 19.1 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein NLRC4_HD2 PF17776.1 ETS80430.1 - 0.00093 19.7 1.6 0.0034 17.9 0.1 3.0 2 0 0 2 2 1 1 NLRC4 helical domain HD2 Adaptin_N PF01602.20 ETS80430.1 - 0.0011 17.6 0.5 0.0011 17.6 0.5 3.1 4 1 0 4 4 4 1 Adaptin N terminal region HEAT_EZ PF13513.6 ETS80430.1 - 0.0019 18.7 4.7 9.4 6.9 0.1 7.0 7 2 1 8 8 7 0 HEAT-like repeat Cnd1 PF12717.7 ETS80430.1 - 0.0036 17.4 7.9 16 5.5 0.0 5.1 5 1 0 5 5 4 0 non-SMC mitotic condensation complex subunit 1 AAA_18 PF13238.6 ETS80430.1 - 0.0042 17.6 0.0 0.016 15.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain VHS PF00790.19 ETS80430.1 - 0.0046 16.8 6.5 2 8.2 0.1 4.7 3 2 1 4 4 4 1 VHS domain Vac14_Fab1_bd PF12755.7 ETS80430.1 - 0.0081 16.7 0.2 1.8 9.2 0.0 3.0 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region NTPase_1 PF03266.15 ETS80430.1 - 0.017 15.1 0.1 0.077 12.9 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_17 PF13207.6 ETS80430.1 - 0.019 15.4 0.3 0.11 12.9 0.0 2.5 2 0 0 2 2 1 0 AAA domain Lipase_3 PF01764.25 ETS80430.1 - 0.037 13.9 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 Lipase (class 3) ATPase PF06745.13 ETS80430.1 - 0.041 13.2 0.2 0.12 11.8 0.0 1.9 2 0 0 2 2 1 0 KaiC Viral_helicase1 PF01443.18 ETS80430.1 - 0.043 13.5 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 ETS80430.1 - 0.052 13.3 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.7 ETS80430.1 - 0.053 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family NOD2_WH PF17779.1 ETS80430.1 - 0.1 13.0 0.0 0.47 10.8 0.0 2.1 1 0 0 1 1 1 0 NOD2 winged helix domain AAA_14 PF13173.6 ETS80430.1 - 0.11 12.6 0.0 0.37 10.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 ETS80430.1 - 0.12 11.3 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 ETS80430.1 - 0.13 12.7 0.0 0.36 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF726 PF05277.12 ETS80430.1 - 0.15 10.9 0.0 0.32 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF726) RasGEF_N_2 PF14663.6 ETS80430.1 - 6.4 7.2 6.3 21 5.6 0.1 4.1 5 0 0 5 5 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain BTB PF00651.31 ETS80431.1 - 7.6e-06 26.1 0.0 1.8e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain GST_N_4 PF17172.4 ETS80431.1 - 0.022 15.5 0.0 0.085 13.6 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain NmrA PF05368.13 ETS80432.1 - 1.6e-28 99.8 0.3 2e-28 99.5 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS80432.1 - 1.5e-18 67.4 0.0 2.2e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ETS80432.1 - 1e-06 29.1 0.7 0.00012 22.3 0.1 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ETS80432.1 - 1.3e-06 28.1 0.1 2.1e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ETS80432.1 - 0.00058 19.1 0.1 0.00088 18.5 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.20 ETS80432.1 - 0.0015 18.6 0.2 0.0028 17.8 0.2 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DFP PF04127.15 ETS80432.1 - 0.0023 17.8 1.1 0.0052 16.6 1.1 1.5 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Shikimate_DH PF01488.20 ETS80432.1 - 0.0038 17.3 0.1 0.0065 16.5 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 ETS80432.1 - 0.0041 16.4 0.8 0.022 14.1 0.5 2.3 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 ETS80432.1 - 0.0049 17.3 0.3 0.0098 16.3 0.3 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 ETS80432.1 - 0.012 15.0 0.1 0.02 14.4 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 ETS80432.1 - 0.014 14.5 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 ETS80432.1 - 0.015 15.2 0.2 0.026 14.4 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ETS80432.1 - 0.029 13.7 0.1 0.049 13.0 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 ETS80432.1 - 0.2 11.8 1.1 0.73 9.9 1.1 1.9 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain COesterase PF00135.28 ETS80433.1 - 4.5e-67 227.1 0.0 7.3e-67 226.4 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS80433.1 - 2.8e-10 40.4 0.0 9.2e-10 38.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS80433.1 - 0.23 10.3 0.1 1.9 7.3 0.1 2.0 1 1 0 1 1 1 0 Steryl acetyl hydrolase PALP PF00291.25 ETS80435.1 - 9.6e-66 222.2 0.1 1.2e-65 221.8 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 ETS80435.1 - 1.5e-11 44.6 0.0 1.4e-07 31.8 0.0 3.0 2 0 0 2 2 2 2 CBS domain FtsJ PF01728.19 ETS80436.1 - 1.7e-14 54.3 0.0 2.6e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Amino_oxidase PF01593.24 ETS80437.1 - 2.2e-57 195.4 0.0 2.7e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ETS80437.1 - 2.6e-08 34.0 0.1 1.7e-07 31.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS80437.1 - 0.0022 17.7 0.0 0.0043 16.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS80437.1 - 0.0055 15.8 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS80437.1 - 0.019 14.2 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS80437.1 - 0.02 14.2 0.2 0.034 13.4 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 ETS80437.1 - 0.046 12.4 0.3 0.092 11.4 0.3 1.5 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.20 ETS80437.1 - 0.071 13.2 0.2 0.4 10.7 0.2 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 ETS80437.1 - 0.11 11.7 0.1 0.23 10.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 ETS80437.1 - 0.15 12.0 0.1 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Ribosomal_S8 PF00410.19 ETS80439.1 - 0.005 16.8 0.0 0.13 12.2 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S8 SnoaL_4 PF13577.6 ETS80439.1 - 0.02 15.0 1.6 0.051 13.7 1.6 1.6 1 0 0 1 1 1 0 SnoaL-like domain Ank_2 PF12796.7 ETS80440.1 - 3.5e-38 130.1 0.3 3.2e-14 53.3 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) DHHC PF01529.20 ETS80440.1 - 1e-34 119.5 12.6 1e-34 119.5 12.6 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_4 PF13637.6 ETS80440.1 - 8.2e-24 83.7 0.7 1.1e-06 29.0 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS80440.1 - 1.9e-22 79.0 0.0 9.3e-07 29.0 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 ETS80440.1 - 4.5e-21 74.3 0.1 1.4e-05 25.4 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 ETS80440.1 - 2.7e-20 70.3 0.5 3.6e-08 33.0 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat TssN PF17555.2 ETS80440.1 - 0.51 9.7 5.7 1.1 8.6 5.7 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN SRPRB PF09439.10 ETS80441.1 - 5.7e-30 104.1 0.0 4.6e-29 101.1 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 ETS80441.1 - 6.3e-05 22.5 0.0 0.00041 19.9 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ETS80441.1 - 0.00019 21.5 0.0 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 ETS80441.1 - 0.0017 18.7 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 ETS80441.1 - 0.006 16.2 0.2 2.6 7.6 0.1 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 ETS80441.1 - 0.0082 16.5 0.7 0.019 15.3 0.7 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 ETS80441.1 - 0.06 13.7 0.0 0.16 12.3 0.0 1.7 1 1 1 2 2 2 0 AAA domain AAA PF00004.29 ETS80441.1 - 0.081 13.4 0.0 0.64 10.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ETS80441.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 ETS80441.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_18 PF13238.6 ETS80441.1 - 0.22 12.1 0.9 0.32 11.5 0.0 1.9 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ETS80441.1 - 0.27 10.9 0.5 16 5.1 0.2 2.4 1 1 0 2 2 2 0 IstB-like ATP binding protein Abhydrolase_6 PF12697.7 ETS80442.1 - 1.4e-11 45.4 2.1 2e-11 44.9 2.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 ETS80442.1 - 0.00019 21.7 0.1 0.00051 20.2 0.1 1.6 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_8 PF06259.12 ETS80442.1 - 0.019 14.6 0.4 0.031 13.9 0.4 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase adh_short_C2 PF13561.6 ETS80443.1 - 1.1e-63 214.9 0.0 1.4e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS80443.1 - 3.7e-44 150.5 0.1 4.7e-44 150.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS80443.1 - 3.7e-13 49.8 0.3 5.7e-13 49.2 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS80443.1 - 8.4e-05 22.1 0.1 0.00011 21.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS80443.1 - 0.0011 18.4 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 ETS80443.1 - 0.0012 19.0 0.0 0.0045 17.2 0.1 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 ETS80443.1 - 0.0021 18.0 0.1 0.0031 17.4 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ETS80443.1 - 0.0064 16.5 0.1 0.0098 15.9 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3Beta_HSD PF01073.19 ETS80443.1 - 0.018 14.1 0.1 0.026 13.5 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ETS80443.1 - 0.022 13.9 0.1 0.68 9.0 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 ETS80443.1 - 0.029 13.7 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 ETS80443.1 - 0.059 12.5 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.6 ETS80443.1 - 0.066 13.6 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 ETS80443.1 - 0.068 13.7 0.2 0.13 12.8 0.0 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase YjeF_N PF03853.15 ETS80443.1 - 0.082 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus F420_oxidored PF03807.17 ETS80443.1 - 0.095 13.3 0.1 1.2 9.8 0.1 2.2 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans_2 PF11951.8 ETS80444.1 - 2.4e-07 29.9 0.3 4.8e-07 28.9 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.13 ETS80445.1 - 3.2e-51 173.9 12.4 4.6e-51 173.4 12.4 1.2 1 0 0 1 1 1 1 RTA1 like protein YqjK PF13997.6 ETS80445.1 - 0.11 12.8 0.4 0.35 11.1 0.2 1.9 2 0 0 2 2 2 0 YqjK-like protein Zn_clus PF00172.18 ETS80446.1 - 3.3e-09 36.7 9.0 6.5e-09 35.8 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS80446.1 - 0.0003 19.7 0.1 0.00043 19.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_N PF08240.12 ETS80447.1 - 1.4e-25 89.3 2.9 2e-25 88.8 2.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS80447.1 - 9.4e-14 51.5 0.0 1.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ETS80447.1 - 0.0042 16.5 0.1 0.0071 15.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ETS80447.1 - 0.025 13.9 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain LtrA PF06772.11 ETS80448.1 - 1.6e-19 70.3 26.7 1.6e-19 70.3 26.7 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Amidase PF01425.21 ETS80450.1 - 3e-55 188.0 0.0 3.8e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Amidase Metallophos PF00149.28 ETS80452.1 - 2.6e-11 44.4 3.5 3.9e-11 43.8 3.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 ETS80452.1 - 0.034 14.4 0.0 0.13 12.5 0.0 1.8 1 1 1 2 2 2 0 5'-nucleotidase, C-terminal domain FAD_binding_7 PF03441.14 ETS80453.1 - 2.2e-58 197.1 1.6 4.1e-58 196.2 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ETS80453.1 - 3.9e-39 134.3 0.0 7.2e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase T6PP_N PF18572.1 ETS80453.1 - 0.0015 18.3 0.5 0.0031 17.3 0.5 1.4 1 0 0 1 1 1 1 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain AAA_2 PF07724.14 ETS80454.1 - 2e-46 158.2 0.0 5.2e-45 153.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ETS80454.1 - 2.4e-33 114.1 3.1 2.4e-33 114.1 3.1 3.6 2 1 1 3 3 3 1 AAA lid domain AAA PF00004.29 ETS80454.1 - 3.9e-27 95.3 0.3 1.2e-14 54.9 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ETS80454.1 - 3.9e-25 87.7 0.6 1.4e-24 85.9 0.6 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ETS80454.1 - 9.2e-16 58.1 0.0 5.5e-10 39.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ETS80454.1 - 6.2e-13 49.2 0.0 6.4e-05 23.2 0.0 4.4 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 ETS80454.1 - 1.5e-11 45.0 11.2 1.6e-06 28.6 0.1 5.1 4 3 1 6 6 4 2 AAA ATPase domain Sigma54_activat PF00158.26 ETS80454.1 - 2e-09 37.4 0.0 8.1e-06 25.6 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain ATPase_2 PF01637.18 ETS80454.1 - 1.6e-06 28.2 0.1 0.031 14.2 0.1 4.3 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 ETS80454.1 - 2.4e-06 27.6 0.0 0.16 12.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 ETS80454.1 - 5e-06 26.4 0.0 0.091 12.5 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 ETS80454.1 - 5.6e-06 26.0 0.0 0.019 14.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 ETS80454.1 - 7.2e-06 26.6 0.0 0.14 12.7 0.0 3.3 2 0 0 2 2 2 2 AAA domain Clp_N PF02861.20 ETS80454.1 - 7.5e-06 26.0 8.5 2.4e-05 24.4 0.2 4.2 4 0 0 4 4 3 1 Clp amino terminal domain, pathogenicity island component AAA_33 PF13671.6 ETS80454.1 - 1.2e-05 25.5 0.0 0.26 11.5 0.0 3.2 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 ETS80454.1 - 1.2e-05 24.8 0.2 0.21 10.9 0.2 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 ETS80454.1 - 4.9e-05 23.6 0.4 0.5 10.6 0.0 3.5 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 ETS80454.1 - 7.5e-05 23.1 0.0 0.57 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 ETS80454.1 - 8.9e-05 22.3 0.0 0.95 9.1 0.0 3.4 3 0 0 3 3 2 2 AAA domain TsaE PF02367.17 ETS80454.1 - 0.0002 21.4 0.0 0.36 10.8 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 ETS80454.1 - 0.00026 20.9 0.0 0.38 10.6 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase RuvB_N PF05496.12 ETS80454.1 - 0.00029 20.6 1.7 5.1 6.8 0.7 4.5 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 ETS80454.1 - 0.00031 20.6 0.0 1.5 8.7 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ETS80454.1 - 0.00057 19.7 0.0 0.56 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 ETS80454.1 - 0.00078 20.0 0.4 1.3 9.6 0.0 3.3 3 0 0 3 3 3 1 ABC transporter AAA_19 PF13245.6 ETS80454.1 - 0.00078 19.8 0.2 0.23 11.8 0.2 3.2 3 1 0 3 3 2 1 AAA domain T2SSE PF00437.20 ETS80454.1 - 0.00087 18.4 0.9 0.018 14.1 0.3 2.9 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 ETS80454.1 - 0.0017 18.0 0.0 1.9 8.3 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain ResIII PF04851.15 ETS80454.1 - 0.0031 17.5 0.0 0.53 10.3 0.0 3.6 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Roc PF08477.13 ETS80454.1 - 0.0052 17.0 0.0 2.3 8.5 0.0 2.9 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 ETS80454.1 - 0.0058 16.6 0.0 0.42 10.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Torsin PF06309.11 ETS80454.1 - 0.0091 16.1 0.0 0.043 13.9 0.0 2.0 2 0 0 2 2 2 1 Torsin Rad17 PF03215.15 ETS80454.1 - 0.011 15.7 0.0 4.7 7.1 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 ETS80454.1 - 0.011 15.6 0.3 0.33 10.9 0.0 3.2 4 0 0 4 4 2 0 NTPase Zeta_toxin PF06414.12 ETS80454.1 - 0.013 14.8 0.0 1.2 8.3 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 ETS80454.1 - 0.025 14.2 0.0 4.4 6.9 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain GAS PF13851.6 ETS80454.1 - 0.034 13.5 9.1 0.1 11.9 9.1 1.8 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_25 PF13481.6 ETS80454.1 - 0.045 13.3 1.5 5.4 6.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain Cep57_CLD_2 PF14197.6 ETS80454.1 - 0.068 13.3 9.7 0.28 11.3 9.7 2.2 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 V_ATPase_I PF01496.19 ETS80454.1 - 0.069 11.1 2.3 0.13 10.2 2.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATP_bind_1 PF03029.17 ETS80454.1 - 0.11 12.2 0.0 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 ETS80454.1 - 0.12 12.1 0.0 7.6 6.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 ETS80454.1 - 0.39 11.2 0.0 0.39 11.2 0.0 4.6 4 1 0 4 4 2 0 AAA domain Spc7 PF08317.11 ETS80454.1 - 0.51 9.2 9.3 1.2 8.0 9.3 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein Macoilin PF09726.9 ETS80454.1 - 0.6 8.6 7.8 0.96 7.9 7.8 1.2 1 0 0 1 1 1 0 Macoilin family Mhr1 PF12829.7 ETS80455.1 - 1.2e-29 102.2 0.0 2e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Sulfotransfer_3 PF13469.6 ETS80456.1 - 0.13 12.6 0.0 13 6.1 0.1 2.9 2 1 0 2 2 2 0 Sulfotransferase family 2OG-FeII_Oxy_3 PF13640.6 ETS80457.1 - 6.7e-08 33.3 0.1 1.5e-07 32.2 0.1 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PIG-X PF08320.12 ETS80458.1 - 8.7e-66 221.8 0.0 1.6e-65 221.0 0.0 1.4 1 0 0 1 1 1 1 PIG-X / PBN1 zf-C3HC4_3 PF13920.6 ETS80459.1 - 0.0056 16.5 11.7 0.0085 15.9 11.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 ETS80459.1 - 0.23 11.4 5.9 0.4 10.6 5.9 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF4360 PF14273.6 ETS80461.1 - 1.6e-64 217.0 0.4 1.6e-64 217.0 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4360) Apt1 PF10351.9 ETS80461.1 - 0.016 14.1 9.6 0.017 14.0 9.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 ETS80461.1 - 0.11 11.6 29.1 0.14 11.3 29.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIA PF03153.13 ETS80461.1 - 0.18 11.8 6.3 0.24 11.4 6.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2834 PF11196.8 ETS80463.1 - 1.5e-05 25.3 1.8 0.14 12.6 0.4 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF2834) AT_hook PF02178.19 ETS80463.1 - 0.61 10.1 12.3 1 9.5 2.4 2.6 2 0 0 2 2 2 0 AT hook motif Arf PF00025.21 ETS80464.1 - 2.6e-38 131.2 0.0 3.2e-25 88.6 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 ETS80464.1 - 7.5e-12 45.1 0.0 6.6e-06 25.5 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 ETS80464.1 - 1.6e-08 34.8 0.0 5e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ETS80464.1 - 9.2e-08 31.8 0.0 0.0012 18.4 0.0 2.3 2 0 0 2 2 2 2 Ras family SRPRB PF09439.10 ETS80464.1 - 1.6e-06 27.7 0.0 0.00011 21.6 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ETS80464.1 - 3.9e-06 26.4 0.0 4.2e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ETS80464.1 - 0.0041 16.7 0.0 0.014 14.9 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ETS80464.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNase_PH PF01138.21 ETS80465.1 - 2.6e-23 83.0 0.0 3.9e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ETS80465.1 - 1.7e-10 40.8 0.0 3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RT_RNaseH PF17917.1 ETS80465.1 - 0.1 12.9 0.0 2.6 8.4 0.0 2.3 1 1 1 2 2 2 0 RNase H-like domain found in reverse transcriptase Cwf_Cwc_15 PF04889.12 ETS80466.1 - 2.5e-84 282.9 22.5 3.3e-84 282.5 22.5 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 ETS80466.1 - 0.013 15.6 22.3 0.018 15.2 22.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 ETS80466.1 - 0.34 9.2 22.1 0.43 8.8 22.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 ETS80466.1 - 0.77 9.1 23.9 0.98 8.8 23.9 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 ETS80466.1 - 1.4 7.0 22.9 1.7 6.8 22.9 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.7 ETS80466.1 - 1.8 6.6 4.6 2.3 6.2 4.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 ETS80466.1 - 4.8 5.8 9.7 5.6 5.6 9.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRN3 PF05327.11 ETS80466.1 - 5.3 5.5 13.4 7.3 5.0 13.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Roughex PF06020.11 ETS80466.1 - 6.7 5.7 15.2 9.5 5.2 15.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF2457 PF10446.9 ETS80466.1 - 6.7 5.7 26.6 10 5.1 26.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.6 ETS80466.1 - 7.6 6.2 19.8 17 5.1 19.8 1.5 1 0 0 1 1 1 0 FAM176 family EBP PF05241.12 ETS80467.1 - 7.2e-50 168.9 7.9 1e-49 168.4 7.9 1.1 1 0 0 1 1 1 1 Emopamil binding protein PRA1 PF03208.19 ETS80467.1 - 0.48 10.0 7.3 0.8 9.3 0.8 2.4 2 1 0 2 2 2 0 PRA1 family protein PBP PF01161.20 ETS80468.1 - 3.8e-16 59.6 0.0 5.4e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Zn_clus PF00172.18 ETS80469.1 - 1.8e-07 31.2 10.3 4.2e-07 30.0 10.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS80469.1 - 0.01 14.9 0.1 0.017 14.1 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Glyco_hydro_75 PF07335.11 ETS80470.1 - 3.5e-65 219.2 0.4 5.3e-65 218.7 0.4 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Kri1 PF05178.12 ETS80471.1 - 7.5e-29 100.3 25.4 7.5e-29 100.3 25.4 5.4 4 1 1 5 5 5 1 KRI1-like family Kri1_C PF12936.7 ETS80471.1 - 8e-26 90.1 0.1 8e-26 90.1 0.1 3.9 2 1 1 3 3 3 1 KRI1-like family C-terminal Ras PF00071.22 ETS80472.1 - 1.9e-58 196.6 0.0 2.2e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS80472.1 - 2.2e-34 118.2 0.0 3.8e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS80472.1 - 2.9e-16 59.4 0.0 3.4e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ETS80472.1 - 6.8e-08 32.3 0.0 9.9e-08 31.7 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ETS80472.1 - 2.8e-07 30.2 0.0 3.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ETS80472.1 - 7.8e-05 22.7 0.0 0.00014 21.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ETS80472.1 - 0.0004 20.8 0.1 0.00066 20.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 ETS80472.1 - 0.0019 18.1 0.1 1.7 8.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase TniB PF05621.11 ETS80472.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein PI3_PI4_kinase PF00454.27 ETS80473.1 - 3.9e-34 118.6 0.0 1.8e-33 116.4 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 ETS80473.1 - 6.2e-19 67.7 0.0 1.3e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 ETS80473.1 - 0.041 13.2 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Fungal_trans PF04082.18 ETS80474.1 - 9.2e-12 44.5 2.0 1.1e-10 41.1 2.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS80474.1 - 1.1e-08 35.0 12.1 1.9e-08 34.3 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox_KN PF05920.11 ETS80475.1 - 1.4e-21 76.1 0.6 2.7e-21 75.2 0.6 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ETS80475.1 - 2.2e-08 33.8 1.0 4.5e-08 32.8 1.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 ETS80476.1 - 2e-07 30.7 0.1 5.3e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Homeodomain Rhodanese PF00581.20 ETS80476.1 - 5.8e-06 26.8 0.0 1.7e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_C14 PF00656.22 ETS80476.1 - 0.038 13.9 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Caspase domain DUF3632 PF12311.8 ETS80477.1 - 3e-16 60.4 0.3 4.6e-16 59.7 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) FrhB_FdhB_N PF04422.13 ETS80477.1 - 0.095 12.9 0.0 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term p450 PF00067.22 ETS80478.1 - 5.2e-24 84.8 0.0 1.3e-23 83.5 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 FGGY_C PF02782.16 ETS80479.1 - 2.1e-27 96.2 0.0 3e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 ETS80479.1 - 9.9e-23 81.0 0.0 4.7e-14 52.5 0.0 2.5 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Cation_efflux PF01545.21 ETS80480.1 - 9.1e-49 165.9 7.0 1.1e-48 165.6 7.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ETS80480.1 - 1.7e-05 24.8 0.1 4.1e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter SIR2 PF02146.17 ETS80481.1 - 6.5e-34 117.4 0.0 1e-33 116.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF2529 PF10740.9 ETS80481.1 - 0.12 12.1 0.0 0.45 10.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2529) DUF5321 PF17254.2 ETS80482.1 - 7.6e-62 207.5 0.2 9.5e-62 207.2 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) DUF1654 PF07867.11 ETS80482.1 - 0.46 10.3 2.0 0.66 9.7 1.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1654) Peptidase_C50 PF03568.17 ETS80483.1 - 1.7e-161 537.8 0.1 6.3e-161 535.9 0.0 2.0 2 0 0 2 2 2 1 Peptidase family C50 RPN7 PF10602.9 ETS80483.1 - 2.5e-06 27.3 4.3 0.35 10.5 0.1 3.8 3 0 0 3 3 3 3 26S proteasome subunit RPN7 TPR_2 PF07719.17 ETS80483.1 - 1.2e-05 25.0 11.4 3 8.2 0.0 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat CHAT PF12770.7 ETS80483.1 - 6.7e-05 22.4 0.1 0.039 13.4 0.0 3.7 3 0 0 3 3 3 1 CHAT domain TPR_12 PF13424.6 ETS80483.1 - 0.00036 20.8 21.3 0.0013 19.0 0.1 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 ETS80483.1 - 0.0013 19.2 10.6 0.59 10.7 0.0 5.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 ETS80483.1 - 0.0023 18.4 3.2 3.9 8.3 0.0 4.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ETS80483.1 - 0.0064 16.3 6.5 17 5.5 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 ETS80483.1 - 0.0086 16.2 9.2 56 4.3 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 ETS80483.1 - 0.08 13.0 5.3 34 4.8 0.3 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS80483.1 - 0.087 13.1 0.1 0.087 13.1 0.1 4.4 6 1 0 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 ETS80483.1 - 0.19 12.6 13.5 14 6.9 0.0 6.7 8 0 0 8 8 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 ETS80483.1 - 1.5 8.8 9.5 63 3.6 0.7 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Fungal_trans PF04082.18 ETS80484.1 - 9.2e-26 90.5 0.0 1.5e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS80484.1 - 3.7e-09 36.6 10.1 5.7e-09 35.9 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LysM PF01476.20 ETS80486.1 - 1.6e-12 47.3 6.7 0.023 14.7 0.1 5.0 5 0 0 5 5 5 4 LysM domain HTH_28 PF13518.6 ETS80486.1 - 0.13 12.4 0.1 30 4.8 0.1 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain Glyco_hydro_18 PF00704.28 ETS80487.1 - 6.1e-72 243.0 0.6 8.8e-72 242.5 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ETS80487.1 - 5.4e-10 39.6 19.9 5.4e-10 39.6 19.9 4.4 4 0 0 4 4 4 1 Chitin recognition protein RAP1 PF07218.11 ETS80490.1 - 0.99 7.6 7.0 1.4 7.1 7.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cep57_CLD PF14073.6 ETS80491.1 - 0.0029 17.6 1.6 0.0057 16.7 1.6 1.4 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 Nup54 PF13874.6 ETS80491.1 - 0.013 15.6 4.5 0.08 13.0 3.2 2.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Nup88 PF10168.9 ETS80491.1 - 0.27 9.0 1.0 5.3 4.7 0.1 2.3 2 1 0 2 2 2 0 Nuclear pore component DUF4407 PF14362.6 ETS80491.1 - 4 6.7 7.1 6.5 6.0 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RRM_1 PF00076.22 ETS80492.1 - 1.4e-15 56.8 0.0 2.1e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3602 PF12223.8 ETS80492.1 - 3.1 8.5 7.4 0.39 11.4 1.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3602) L31 PF09784.9 ETS80493.1 - 1.1e-41 141.4 2.5 1.2e-34 118.8 0.4 2.0 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L31 Sedlin_N PF04628.13 ETS80494.1 - 4.7e-46 156.1 0.0 5.5e-46 155.9 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 ETS80494.1 - 0.00018 21.4 0.0 0.12 12.3 0.0 2.2 1 1 1 2 2 2 2 Sybindin-like family DUF4110 PF13422.6 ETS80494.1 - 0.09 12.9 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) CENP-T_C PF15511.6 ETS80495.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 ETS80495.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 ETS80495.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 ETS80495.1 - 0.00036 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 ETS80495.1 - 0.00042 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 ETS80495.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ETS80495.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 ETS80495.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 ETS80495.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region TPR_2 PF07719.17 ETS80496.1 - 3.3e-41 136.1 38.2 9.4e-06 25.4 0.1 11.4 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_1 PF00515.28 ETS80496.1 - 1.2e-40 135.7 33.1 2.7e-07 30.1 0.0 10.6 11 0 0 11 11 11 7 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS80496.1 - 7e-32 109.5 27.2 2.6e-23 82.1 0.3 6.0 5 1 2 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 ETS80496.1 - 3.8e-27 92.2 27.0 0.0025 17.9 0.1 10.5 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_14 PF13428.6 ETS80496.1 - 9.1e-27 91.5 20.2 0.0013 19.3 1.0 10.6 5 2 7 12 12 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 ETS80496.1 - 3.5e-22 78.5 27.4 0.0055 17.0 1.1 8.9 5 3 1 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 ETS80496.1 - 3.5e-22 77.8 27.7 6.8e-07 28.9 2.2 10.3 6 3 5 11 11 11 6 TPR repeat TPR_19 PF14559.6 ETS80496.1 - 4.2e-22 78.4 21.3 1.4e-08 35.1 4.4 7.4 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 ETS80496.1 - 9.1e-21 72.7 20.4 0.041 14.3 0.6 9.9 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_7 PF13176.6 ETS80496.1 - 9.8e-19 66.0 17.4 0.0041 17.1 0.0 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 ETS80496.1 - 4e-18 65.8 33.2 9.1e-08 32.6 2.0 8.9 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 ETS80496.1 - 2.4e-13 49.8 20.7 0.1 13.3 0.0 10.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.6 ETS80496.1 - 3.7e-12 46.2 9.2 5.5e-05 23.2 0.6 5.9 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 ETS80496.1 - 2e-07 30.5 8.6 0.0059 15.9 1.4 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 ETS80496.1 - 5.1e-05 23.5 3.1 0.063 13.9 0.6 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 ETS80496.1 - 0.00052 20.3 3.2 0.21 12.0 0.7 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2225 PF09986.9 ETS80496.1 - 0.003 17.3 6.8 3.7 7.2 2.2 4.0 2 1 2 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2225) NARP1 PF12569.8 ETS80496.1 - 0.007 15.3 3.4 1.9 7.3 0.4 3.6 4 0 0 4 4 4 2 NMDA receptor-regulated protein 1 ChAPs PF09295.10 ETS80496.1 - 0.099 11.6 1.2 3.6 6.5 0.2 3.4 3 1 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 ETS80496.1 - 0.1 12.7 11.8 0.77 9.9 0.1 5.2 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.12 ETS80496.1 - 1.1 10.1 10.1 30 5.5 0.0 5.7 7 0 0 7 7 5 0 Sel1 repeat TMEM208_SND2 PF05620.11 ETS80497.1 - 1.9e-50 170.9 0.0 2.1e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF3605 PF12239.8 ETS80498.1 - 2.2e-57 193.7 0.0 2.5e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FAD_binding_6 PF00970.24 ETS80499.1 - 4.5e-30 103.9 0.0 7e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ETS80499.1 - 2.8e-28 98.7 0.0 4e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ETS80499.1 - 2.2e-05 24.6 0.0 0.0071 16.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Abhydrolase_3 PF07859.13 ETS80500.1 - 2.6e-20 73.2 0.0 3.7e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS80500.1 - 1.4e-18 66.9 0.0 1.8e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 ETS80500.1 - 0.079 11.8 0.1 0.37 9.6 0.0 1.8 2 0 0 2 2 2 0 Carboxylesterase family CBFD_NFYB_HMF PF00808.23 ETS80501.1 - 2.4e-13 50.2 2.3 4e-13 49.4 2.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ETS80501.1 - 0.00079 19.8 0.3 0.00079 19.8 0.3 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 ETS80501.1 - 0.079 13.1 4.0 0.052 13.7 1.9 1.7 2 0 0 2 2 2 0 hTAFII28-like protein conserved region SesA PF17107.5 ETS80502.1 - 6e-06 26.5 2.2 0.0002 21.5 0.0 3.0 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 ETS80502.1 - 7.5e-06 25.5 1.4 0.0093 15.3 0.1 2.3 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins DUF1664 PF07889.12 ETS80502.1 - 0.02 14.9 3.2 3.6 7.7 0.4 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) MCPsignal PF00015.21 ETS80502.1 - 0.033 14.0 10.3 0.83 9.4 2.0 3.2 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FlaC_arch PF05377.11 ETS80502.1 - 0.041 14.3 0.7 36 4.8 0.1 4.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) V-SNARE PF05008.15 ETS80502.1 - 0.1 13.0 2.6 10 6.6 0.3 3.6 4 0 0 4 4 4 0 Vesicle transport v-SNARE protein N-terminus RAP-1 PF03085.15 ETS80502.1 - 0.25 11.0 0.9 0.41 10.3 0.9 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) COG2 PF06148.11 ETS80502.1 - 0.46 10.6 2.7 2.7 8.1 0.2 2.9 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_GPO PF05929.11 ETS80502.1 - 0.67 9.5 7.2 1 8.9 1.5 2.3 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Laminin_II PF06009.12 ETS80502.1 - 1.1 9.3 11.7 2 8.4 2.1 3.5 2 1 1 3 3 3 0 Laminin Domain II DUF2730 PF10805.8 ETS80502.1 - 1.9 8.6 3.6 4.4 7.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) BLOC1_2 PF10046.9 ETS80502.1 - 2.4 8.5 4.1 47 4.4 0.3 3.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Exonuc_VII_L PF02601.15 ETS80502.1 - 3.4 7.1 8.9 2.6 7.5 3.9 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF948 PF06103.11 ETS80502.1 - 4 7.8 9.4 3.4 8.0 2.2 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) BORCS6 PF10157.9 ETS80502.1 - 7.6 6.8 9.7 1.3 9.2 4.2 2.4 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 6 SNARE_assoc PF09335.11 ETS80503.1 - 7e-18 65.2 6.9 7e-18 65.2 6.9 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein Phage_holin_3_6 PF07332.11 ETS80503.1 - 0.022 14.8 12.7 0.12 12.4 1.8 2.6 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III GRIM-19 PF06212.12 ETS80503.1 - 0.028 14.4 3.2 3.6 7.6 0.0 3.5 4 0 0 4 4 4 0 GRIM-19 protein Serglycin PF04360.12 ETS80503.1 - 0.05 13.6 0.4 0.088 12.8 0.4 1.3 1 0 0 1 1 1 0 Serglycin SpoIIIAH PF12685.7 ETS80503.1 - 0.096 12.5 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF1980 PF09323.10 ETS80503.1 - 0.66 9.9 2.5 1.8 8.4 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF3278 PF11683.8 ETS80503.1 - 0.94 9.6 5.5 0.15 12.2 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) HemY_N PF07219.13 ETS80503.1 - 1.5 9.1 4.1 2.4 8.4 0.1 2.8 3 0 0 3 3 3 0 HemY protein N-terminus MRJP PF03022.16 ETS80504.1 - 2.9e-19 69.5 0.0 3.7e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein Ribosomal_S13 PF00416.22 ETS80506.1 - 2.6e-55 186.3 2.7 3e-55 186.1 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 ETS80506.1 - 0.0072 15.1 0.0 0.016 14.0 0.0 1.4 1 1 1 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF2746 PF10874.8 ETS80506.1 - 0.049 14.1 0.0 0.087 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) SBDS_C PF09377.10 ETS80507.1 - 5.3e-47 158.6 0.0 9.4e-47 157.8 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 ETS80507.1 - 1.4e-34 118.0 0.2 2.4e-34 117.3 0.2 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF627 PF04781.12 ETS80507.1 - 0.13 12.3 0.1 0.78 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF627) Peptidase_S10 PF00450.22 ETS80508.1 - 1e-131 440.2 2.3 1.2e-131 440.0 2.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 ETS80508.1 - 5.1e-15 56.1 0.1 1.5e-14 54.6 0.1 1.8 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide Cas1_AcylT PF07779.12 ETS80509.1 - 1.4e-105 354.0 15.1 3.7e-105 352.6 15.1 1.5 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p GFA PF04828.14 ETS80510.1 - 1.2e-19 70.5 1.4 1.6e-19 70.1 1.4 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme GTP1_OBG PF01018.22 ETS80513.1 - 0.018 14.6 0.4 0.033 13.8 0.4 1.4 1 0 0 1 1 1 0 GTP1/OBG PCDO_beta_N PF12391.8 ETS80514.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal Ribosomal_L22 PF00237.19 ETS80516.1 - 6.7e-41 138.7 0.1 9e-41 138.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Fibrillarin PF01269.17 ETS80517.1 - 2.4e-102 340.9 0.0 2.9e-102 340.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 ETS80517.1 - 1.1e-05 25.3 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 ETS80517.1 - 0.0058 16.3 0.0 0.022 14.4 0.0 1.8 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 ETS80517.1 - 0.037 13.8 0.1 0.053 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Dicty_CAR PF05462.11 ETS80519.1 - 3.8e-16 59.1 6.6 3.8e-16 59.1 6.6 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 ETS80519.1 - 1.5e-10 40.8 5.1 2.6e-10 40.0 5.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3 PF11710.8 ETS80519.1 - 1.4e-09 38.1 9.8 2.5e-09 37.2 9.8 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 ETS80519.1 - 4.2e-07 29.6 1.4 5.9e-07 29.1 1.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 ETS80519.1 - 0.0028 17.1 3.0 0.0041 16.5 3.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Frizzled PF01534.17 ETS80519.1 - 0.056 12.5 11.1 0.084 11.9 3.8 2.3 1 1 1 2 2 2 0 Frizzled/Smoothened family membrane region Ocular_alb PF02101.15 ETS80519.1 - 2.7 6.8 7.5 36 3.1 7.2 2.3 2 1 0 2 2 2 0 Ocular albinism type 1 protein Peroxidase_2 PF01328.17 ETS80520.1 - 8.3e-56 189.5 0.0 1.3e-55 188.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Methyltransf_11 PF08241.12 ETS80521.1 - 0.016 15.8 0.0 0.041 14.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Xan_ur_permease PF00860.20 ETS80522.1 - 5.7e-23 81.2 33.6 2.9e-22 78.9 32.3 2.4 2 1 0 2 2 2 1 Permease family DUF5464 PF17552.2 ETS80522.1 - 0.014 15.6 0.2 0.14 12.4 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5464) CASP_C PF08172.12 ETS80523.1 - 1.2e-94 316.4 0.0 1.2e-94 316.4 0.0 3.4 3 1 0 4 4 4 1 CASP C terminal TolA_bind_tri PF16331.5 ETS80523.1 - 0.00013 22.0 33.7 0.049 13.7 0.5 5.6 5 0 0 5 5 5 3 TolA binding protein trimerisation Cep57_MT_bd PF06657.13 ETS80523.1 - 0.0041 17.5 3.9 0.0041 17.5 3.9 5.9 6 2 1 7 7 7 2 Centrosome microtubule-binding domain of Cep57 APG6_N PF17675.1 ETS80523.1 - 0.0061 17.1 56.5 0.85 10.1 16.5 5.2 2 1 3 5 5 5 3 Apg6 coiled-coil region PI3K_P85_iSH2 PF16454.5 ETS80523.1 - 0.0078 15.8 38.7 0.034 13.7 13.4 4.8 3 1 2 5 5 5 3 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ERM PF00769.19 ETS80523.1 - 0.018 14.8 2.9 0.018 14.8 2.9 4.4 4 1 0 4 4 3 0 Ezrin/radixin/moesin family SlyX PF04102.12 ETS80523.1 - 0.15 12.7 0.0 0.15 12.7 0.0 6.1 7 0 0 7 7 7 0 SlyX Tropomyosin_1 PF12718.7 ETS80523.1 - 0.38 10.9 54.7 1.4 9.1 4.7 5.4 3 1 2 5 5 5 0 Tropomyosin like DUF1664 PF07889.12 ETS80523.1 - 0.39 10.7 0.1 0.39 10.7 0.1 5.8 4 1 2 6 6 6 0 Protein of unknown function (DUF1664) GTP-bdg_M PF16360.5 ETS80523.1 - 0.58 10.8 0.1 0.58 10.8 0.1 6.2 4 2 3 7 7 7 0 GTP-binding GTPase Middle Region DUF5633 PF18656.1 ETS80523.1 - 0.84 9.6 3.2 1.8 8.5 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5633) CENP-F_leu_zip PF10473.9 ETS80523.1 - 2.2 8.3 56.6 0.086 12.9 1.7 5.7 4 1 2 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_I PF06008.14 ETS80523.1 - 2.5 7.7 35.7 4 7.1 1.3 4.8 4 1 0 4 4 4 0 Laminin Domain I DUF4407 PF14362.6 ETS80523.1 - 2.9 7.2 38.3 5.1 6.4 2.3 4.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) SKA1 PF07160.12 ETS80523.1 - 3.6 7.4 27.2 16 5.3 0.0 4.7 3 1 0 4 4 4 0 Spindle and kinetochore-associated protein 1 Fez1 PF06818.15 ETS80523.1 - 8 6.9 45.3 5.2 7.5 20.2 4.4 3 1 2 5 5 5 0 Fez1 ADIP PF11559.8 ETS80523.1 - 8.3 6.5 63.0 0.021 14.9 7.8 6.7 5 2 2 7 7 7 0 Afadin- and alpha -actinin-Binding Mst1_SARAH PF11629.8 ETS80523.1 - 8.3 6.6 9.1 6.2 7.0 1.2 3.9 2 1 1 3 3 3 0 C terminal SARAH domain of Mst1 STAT_alpha PF01017.20 ETS80523.1 - 8.6 6.2 22.3 0.97 9.3 0.1 3.8 3 2 1 4 4 4 0 STAT protein, all-alpha domain DUF1192 PF06698.11 ETS80523.1 - 8.6 6.5 12.8 0.27 11.3 0.9 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF3455 PF11937.8 ETS80524.1 - 1.2e-42 146.0 0.4 1.7e-42 145.5 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 ETS80524.1 - 0.0018 18.4 1.1 0.0018 18.4 1.1 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2990) Peptidase_C12 PF01088.21 ETS80525.1 - 9.3e-71 237.9 0.0 1.2e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 ETS80525.1 - 7.6e-10 38.5 0.2 1.6e-09 37.5 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Vps39_2 PF10367.9 ETS80526.1 - 8.7e-07 29.4 0.0 2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 ETS80526.1 - 0.00062 20.0 0.0 0.0067 16.7 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Troponin-I_N PF11636.8 ETS80526.1 - 6.1 6.9 8.2 24 5.0 8.2 2.1 1 0 0 1 1 1 0 Troponin I residues 1-32 WD40 PF00400.32 ETS80527.1 - 6e-39 131.3 33.0 5.5e-08 33.3 0.0 13.0 15 0 0 15 15 14 6 WD domain, G-beta repeat Utp12 PF04003.12 ETS80527.1 - 1.4e-25 89.6 0.0 2.1e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 ETS80527.1 - 3.2e-23 81.8 0.0 0.00046 20.4 0.0 10.2 3 2 5 10 10 10 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS80527.1 - 3.5e-08 32.8 1.2 1.4 7.8 0.0 6.4 3 2 3 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ETS80527.1 - 1.4e-07 31.6 0.6 0.16 11.9 0.1 5.1 5 2 2 7 7 7 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 ETS80527.1 - 0.003 16.9 0.1 8.6 5.6 0.0 4.0 4 1 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 ETS80527.1 - 0.0031 16.9 0.0 0.42 9.9 0.0 3.1 2 1 1 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 ETS80527.1 - 0.029 12.9 0.0 4.2 5.8 0.0 3.2 2 1 1 3 3 3 0 Cytochrome D1 heme domain RPN1_RPN2_N PF17781.1 ETS80527.1 - 0.22 10.9 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain Utp13 PF08625.11 ETS80527.1 - 0.25 11.2 0.4 0.91 9.4 0.3 2.1 2 1 0 2 2 2 0 Utp13 specific WD40 associated domain PD40 PF07676.12 ETS80527.1 - 4.5 7.3 6.0 28 4.8 0.1 4.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat BCS1_N PF08740.11 ETS80528.1 - 1.3e-44 152.4 0.4 2.1e-44 151.8 0.4 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 ETS80528.1 - 2.2e-16 60.5 0.0 6.3e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ETS80528.1 - 0.00048 19.9 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 ETS80528.1 - 0.018 14.6 0.0 0.056 13.0 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 ETS80528.1 - 0.03 14.3 0.0 0.086 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pox_RNA_Pol_19 PF05320.12 ETS80528.1 - 0.072 13.1 0.0 0.29 11.1 0.1 1.9 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit ATPase PF06745.13 ETS80528.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 ETS80528.1 - 0.088 13.1 0.0 16 5.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 ETS80528.1 - 0.11 12.8 0.1 0.32 11.4 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain ADH_zinc_N PF00107.26 ETS80529.1 - 3.2e-09 36.9 0.1 6.2e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AMP-binding PF00501.28 ETS80530.1 - 8.5e-20 70.7 0.0 5.2e-19 68.1 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme NPCC PF08058.11 ETS80531.1 - 7.7e-25 87.4 0.0 1.2e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore complex component FAD_binding_3 PF01494.19 ETS80532.1 - 1e-61 209.1 0.1 1.3e-61 208.8 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS80532.1 - 4.8e-07 29.7 0.4 1.6e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS80532.1 - 6e-05 22.4 0.0 8.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS80532.1 - 0.00017 20.8 0.0 0.00023 20.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ETS80532.1 - 0.00018 21.7 0.1 0.00052 20.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS80532.1 - 0.00021 20.7 0.0 0.00037 19.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS80532.1 - 0.0012 17.6 0.1 0.002 16.9 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Phe_hydrox_dim PF07976.12 ETS80532.1 - 0.004 17.2 0.0 0.013 15.6 0.0 1.9 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_oxidored PF12831.7 ETS80532.1 - 0.0046 16.4 0.3 0.0072 15.7 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 ETS80532.1 - 0.0079 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Thi4 PF01946.17 ETS80532.1 - 0.037 13.3 0.1 0.066 12.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 ETS80532.1 - 0.063 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 ETS80532.1 - 0.17 12.3 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding PHA_synth_III_E PF09712.10 ETS80533.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) SPC22 PF04573.12 ETS80534.1 - 1e-40 139.0 1.1 2.1e-39 134.8 1.1 2.0 1 1 0 1 1 1 1 Signal peptidase subunit MCM PF00493.23 ETS80535.1 - 2.2e-105 350.7 0.1 7.7e-105 348.9 0.0 1.8 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 ETS80535.1 - 1.7e-35 121.6 0.2 3.3e-35 120.7 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ETS80535.1 - 1.7e-28 98.8 1.1 4.1e-28 97.6 1.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ETS80535.1 - 4e-12 46.6 0.3 1e-11 45.4 0.3 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ETS80535.1 - 8.2e-07 28.6 0.0 0.0002 20.8 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ETS80535.1 - 4.3e-05 23.5 0.0 9.4e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ETS80535.1 - 0.00025 20.9 0.1 0.0016 18.3 0.0 2.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ETS80535.1 - 0.049 13.3 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 ETS80535.1 - 0.092 13.2 0.5 0.4 11.1 0.0 2.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Vps54 PF07928.12 ETS80536.1 - 8.4e-52 175.1 1.1 1.8e-51 174.1 0.0 2.2 3 0 0 3 3 2 1 Vps54-like protein Vps54_N PF10475.9 ETS80536.1 - 8.2e-08 31.9 2.1 8.2e-08 31.9 2.1 1.7 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF3490 PF11995.8 ETS80536.1 - 0.0092 15.8 5.8 0.12 12.2 0.2 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3490) Sec8_exocyst PF04048.14 ETS80536.1 - 0.013 15.4 1.1 0.052 13.4 0.8 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain FliJ PF02050.16 ETS80536.1 - 0.023 14.9 1.3 0.076 13.3 1.3 1.9 1 0 0 1 1 1 0 Flagellar FliJ protein COG2 PF06148.11 ETS80536.1 - 0.024 14.8 2.0 0.091 12.8 2.0 2.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 OmpH PF03938.14 ETS80536.1 - 0.12 12.7 0.7 0.43 10.9 0.7 1.9 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 ETS80536.1 - 0.15 10.9 2.9 0.32 9.8 2.9 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1843 PF08898.10 ETS80536.1 - 0.82 10.2 2.3 1 9.9 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) ZapB PF06005.12 ETS80536.1 - 1.3 9.5 5.1 5.3 7.5 5.1 2.1 1 0 0 1 1 1 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 ETS80536.1 - 1.8 8.8 6.5 0.35 11.1 1.9 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 ETS80536.1 - 3.3 8.2 6.4 0.84 10.2 2.0 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region MTHFR PF02219.17 ETS80537.1 - 6.3e-103 344.0 0.0 9.2e-103 343.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Aminotran_1_2 PF00155.21 ETS80538.1 - 7.4e-12 45.1 0.0 6.6e-09 35.4 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II HTH_WhiA PF02650.14 ETS80539.1 - 0.019 15.3 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 WhiA C-terminal HTH domain PQ-loop PF04193.14 ETS80540.1 - 4e-18 64.9 4.5 7.6e-12 44.8 0.6 2.5 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 ETS80540.1 - 0.0057 17.5 3.7 0.085 13.7 3.7 2.1 1 1 0 1 1 1 1 ER lumen protein retaining receptor WSC PF01822.19 ETS80541.1 - 3.2e-69 229.1 66.9 2.9e-18 65.8 12.4 4.9 4 0 0 4 4 4 4 WSC domain peroxidase PF00141.23 ETS80541.1 - 6.9e-20 71.7 0.1 1.5e-19 70.6 0.1 1.5 1 0 0 1 1 1 1 Peroxidase Pkinase PF00069.25 ETS80542.1 - 6.7e-70 235.5 0.0 9.3e-70 235.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS80542.1 - 4.1e-49 167.2 0.0 5.7e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS80542.1 - 2.9e-07 30.1 0.0 6.7e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ETS80542.1 - 3.7e-06 26.0 0.0 8.6e-06 24.8 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Glycos_transf_2 PF00535.26 ETS80542.1 - 0.05 13.4 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 Kdo PF06293.14 ETS80542.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Transglut_core PF01841.19 ETS80543.1 - 1.1e-10 41.9 0.3 1.1e-10 41.9 0.3 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily SH3_2 PF07653.17 ETS80543.1 - 1.9e-08 33.9 0.2 5.8e-08 32.3 0.2 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ETS80543.1 - 2.2e-07 30.4 0.1 2.2e-07 30.4 0.1 2.9 4 0 0 4 4 4 1 SH3 domain SH3_9 PF14604.6 ETS80543.1 - 0.0015 18.4 1.5 0.0018 18.1 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain Sugar_tr PF00083.24 ETS80544.1 - 1.3e-77 261.7 22.9 1.4e-77 261.5 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS80544.1 - 2.2e-15 56.5 22.9 2.2e-15 56.5 22.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS80544.1 - 4.1e-07 29.6 3.6 4.1e-07 29.6 3.6 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4190 PF13828.6 ETS80544.1 - 0.029 14.1 2.5 0.038 13.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Phage_holin_2_4 PF16082.5 ETS80544.1 - 0.55 10.0 3.8 5 6.9 0.6 3.0 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like HpcH_HpaI PF03328.14 ETS80545.1 - 3.7e-22 78.6 0.0 4.6e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DIT1_PvcA PF05141.12 ETS80546.1 - 4.6e-85 285.4 0.0 5.9e-85 285.1 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DIT1_PvcA PF05141.12 ETS80547.1 - 1.6e-84 283.7 0.0 2e-84 283.4 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TPR_17 PF13431.6 ETS80547.1 - 0.15 12.5 0.0 0.39 11.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat NAD_binding_4 PF07993.12 ETS80548.1 - 1.4e-34 119.4 0.0 2.2e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 ETS80548.1 - 2.2e-22 79.3 0.0 3.3e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 ETS80548.1 - 2e-11 43.8 0.0 3.3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 ETS80548.1 - 0.0024 18.2 0.1 0.0062 16.9 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 ETS80548.1 - 0.1 11.6 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ETS80548.1 - 0.12 11.4 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DJ-1_PfpI PF01965.24 ETS80549.1 - 3.5e-13 49.7 0.0 4.3e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family OAM_alpha PF16552.5 ETS80550.1 - 0.12 12.2 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit Pyr_redox_3 PF13738.6 ETS80551.1 - 3.1e-24 85.8 0.0 4.8e-22 78.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS80551.1 - 3.2e-21 75.8 0.0 3.9e-19 69.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ETS80551.1 - 4.8e-17 61.6 0.0 1.4e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ETS80551.1 - 3e-11 43.1 0.8 3.2e-09 36.4 0.0 3.2 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 ETS80551.1 - 3.9e-08 33.7 1.0 5.1e-05 23.8 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS80551.1 - 1.2e-07 31.8 0.0 0.0011 19.1 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ETS80551.1 - 4.5e-07 29.5 0.7 0.0018 17.6 0.9 3.0 2 1 1 3 3 3 2 FAD binding domain GIDA PF01134.22 ETS80551.1 - 1.5e-06 27.6 0.8 0.069 12.2 0.5 3.2 3 0 0 3 3 3 2 Glucose inhibited division protein A DAO PF01266.24 ETS80551.1 - 3.3e-05 23.7 0.5 0.021 14.4 1.1 3.4 3 1 0 4 4 4 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 ETS80551.1 - 5e-05 23.4 0.1 0.0056 16.7 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 ETS80551.1 - 7.5e-05 22.0 1.1 0.0028 16.8 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 ETS80551.1 - 9.5e-05 21.6 0.0 0.0082 15.2 0.1 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 ETS80551.1 - 0.00028 20.3 0.0 0.23 10.8 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 ETS80551.1 - 0.00042 19.6 0.1 0.52 9.5 0.0 2.3 2 0 0 2 2 2 2 Thi4 family ApbA PF02558.16 ETS80551.1 - 0.00078 19.1 0.3 0.027 14.1 0.0 2.7 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 ETS80551.1 - 0.0014 17.4 0.6 0.19 10.4 0.4 2.9 3 0 0 3 3 3 1 HI0933-like protein IlvN PF07991.12 ETS80551.1 - 0.0041 16.7 0.1 0.55 9.8 0.0 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 ETS80551.1 - 0.0045 17.4 1.1 0.017 15.5 0.1 2.3 2 1 0 2 2 2 1 Putative NAD(P)-binding TrkA_N PF02254.18 ETS80551.1 - 0.0049 17.1 0.2 5.2 7.4 0.0 2.8 3 0 0 3 3 2 1 TrkA-N domain SnoaL_2 PF12680.7 ETS80551.1 - 0.0054 17.3 0.1 0.045 14.4 0.0 2.6 3 0 0 3 3 3 1 SnoaL-like domain 3HCDH_N PF02737.18 ETS80551.1 - 0.011 15.6 0.4 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4147 PF13660.6 ETS80551.1 - 0.023 14.3 0.0 0.95 9.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4147) XdhC_C PF13478.6 ETS80551.1 - 0.058 13.9 0.0 8.1 7.0 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_Gly3P_dh_N PF01210.23 ETS80551.1 - 0.19 11.7 0.4 3.3 7.7 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Amidase PF01425.21 ETS80552.1 - 1e-34 120.3 6.1 1.2e-33 116.8 3.1 2.1 2 0 0 2 2 2 2 Amidase Glyco_hydro_43 PF04616.14 ETS80553.1 - 6.5e-29 101.1 0.1 1.1e-28 100.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 WD40_3 PF15911.5 ETS80553.1 - 0.15 12.1 0.2 9.5 6.3 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF5005 PF16396.5 ETS80553.1 - 0.34 9.5 1.6 4.6 5.8 0.1 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF5005) Adeno_E3_CR2 PF02439.15 ETS80554.1 - 0.33 10.7 1.9 0.98 9.2 1.9 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 GLEYA PF10528.9 ETS80555.1 - 1e-30 106.0 0.4 3.1e-30 104.4 0.4 1.9 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 ETS80555.1 - 1.4e-07 31.5 0.1 6.3e-07 29.3 0.1 2.1 1 1 0 1 1 1 1 PA14 domain GST_N_3 PF13417.6 ETS80556.1 - 2.1e-07 31.2 0.0 4.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ETS80556.1 - 0.00058 20.2 0.0 0.0064 16.8 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ETS80556.1 - 0.0027 18.0 0.0 0.008 16.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS80556.1 - 0.078 13.0 0.1 0.16 12.1 0.1 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain A_deaminase PF00962.22 ETS80558.1 - 3.4e-62 210.7 0.0 3.9e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase V_ATPase_prox PF18274.1 ETS80558.1 - 0.19 11.7 0.9 2.5 8.1 0.1 2.9 3 0 0 3 3 3 0 Vacuolar ATPase Subunit I N-terminal proximal lobe ABC_tran PF00005.27 ETS80559.1 - 2.7e-15 57.1 0.1 2.3e-14 54.1 0.1 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ETS80559.1 - 6.9e-11 42.5 2.7 0.00021 21.2 0.7 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF3584 PF12128.8 ETS80559.1 - 0.001 16.7 0.4 0.0014 16.3 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 ETS80559.1 - 0.0011 18.7 0.1 0.0021 17.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ETS80559.1 - 0.0075 16.8 0.1 0.011 16.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 ETS80559.1 - 0.0081 15.6 0.0 2.8 7.3 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 ETS80559.1 - 0.017 15.4 0.2 0.031 14.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 ETS80559.1 - 0.021 14.4 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_15 PF13175.6 ETS80559.1 - 0.032 13.9 0.1 0.045 13.5 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 ETS80559.1 - 0.04 14.3 0.5 0.067 13.6 0.5 1.5 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 ETS80559.1 - 0.05 13.3 0.1 0.076 12.7 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 ETS80559.1 - 0.061 13.2 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase Arf PF00025.21 ETS80559.1 - 0.066 12.7 0.3 0.2 11.1 0.2 1.8 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_22 PF13401.6 ETS80559.1 - 0.082 13.2 0.3 0.25 11.6 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ETS80559.1 - 0.082 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ETS80559.1 - 0.097 13.1 0.1 0.24 11.8 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 ETS80559.1 - 0.11 11.1 0.1 0.15 10.7 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ETS80559.1 - 0.18 12.0 0.2 0.31 11.2 0.2 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ETS80559.1 - 0.2 11.5 0.2 0.33 10.9 0.2 1.3 1 0 0 1 1 1 0 NACHT domain CENP-I PF07778.11 ETS80560.1 - 4.2e-35 121.5 0.0 9.2e-34 117.0 0.0 2.0 1 1 0 1 1 1 1 Mis6 Acetyltransf_1 PF00583.25 ETS80561.1 - 9e-06 25.9 0.0 2.6e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS80561.1 - 0.0009 19.6 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Prenyltrans PF00432.21 ETS80561.1 - 0.02 14.6 0.1 0.04 13.7 0.1 1.5 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Acetyltransf_10 PF13673.7 ETS80561.1 - 0.06 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nuc_deoxyri_tr2 PF15891.5 ETS80561.1 - 0.19 12.1 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like DUF3384 PF11864.8 ETS80562.1 - 3.3e-130 435.2 0.7 1.3e-129 433.2 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 ETS80562.1 - 3.3e-53 180.0 0.0 6.5e-53 179.0 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 ETS80562.1 - 1e-45 156.4 1.3 2.9e-39 135.2 0.1 3.4 3 0 0 3 3 3 3 Tuberin CAS_CSE1 PF03378.15 ETS80563.1 - 1.4e-173 577.5 0.0 2.7e-173 576.6 0.0 1.5 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 ETS80563.1 - 3.1e-153 510.0 6.0 3.6e-153 509.8 4.9 1.6 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.19 ETS80563.1 - 1.2e-14 54.0 0.2 5.8e-14 51.8 0.2 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 ETS80563.1 - 0.0017 18.4 4.2 0.052 13.6 0.0 4.3 4 1 1 5 5 5 1 Exportin 1-like protein DUF1071 PF06378.11 ETS80563.1 - 0.047 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Phyto_Pns9_10 PF05878.11 ETS80563.1 - 0.065 12.4 0.1 0.16 11.1 0.1 1.6 1 1 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Peptidase_S10 PF00450.22 ETS80564.1 - 5.9e-82 276.3 1.8 7.4e-82 276.0 1.8 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase TPR_1 PF00515.28 ETS80566.1 - 5.9e-31 105.0 6.7 0.00012 21.7 0.4 9.8 9 0 0 9 9 9 6 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS80566.1 - 2.1e-29 101.5 14.2 3.7e-24 84.8 0.2 5.1 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 ETS80566.1 - 4.5e-29 98.2 23.6 0.00076 19.4 0.2 10.8 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 ETS80566.1 - 3.1e-23 82.0 16.5 0.0016 18.9 0.0 7.8 5 2 3 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 ETS80566.1 - 2.3e-20 71.0 3.2 0.016 15.4 0.1 9.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 ETS80566.1 - 3e-20 72.3 19.3 1.8e-09 37.7 0.1 8.7 7 2 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 ETS80566.1 - 1.3e-16 59.9 22.1 0.021 15.6 0.1 9.6 5 3 4 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 ETS80566.1 - 5.7e-13 49.3 23.4 2.2e-05 25.0 0.6 8.8 6 4 2 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 ETS80566.1 - 4.6e-12 45.4 15.9 0.0019 17.9 0.0 8.0 7 1 1 8 8 8 3 TPR repeat TPR_10 PF13374.6 ETS80566.1 - 1.9e-11 43.5 8.7 0.00021 21.0 0.1 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 ETS80566.1 - 8.7e-09 34.8 15.2 4.3 7.6 0.1 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 ETS80566.1 - 9.5e-09 35.3 13.8 0.94 10.3 0.1 8.9 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 ETS80566.1 - 1.9e-07 31.1 9.5 0.00028 20.9 0.3 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat PPR PF01535.20 ETS80566.1 - 0.0017 18.5 0.2 4.3 7.8 0.0 5.1 5 0 0 5 5 5 1 PPR repeat Coatomer_E PF04733.14 ETS80566.1 - 0.0071 15.8 0.2 4.8 6.5 0.0 3.9 4 1 1 5 5 5 1 Coatomer epsilon subunit TPR_4 PF07721.14 ETS80566.1 - 0.018 15.6 8.4 1.4 9.8 0.1 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 ETS80566.1 - 0.023 14.2 0.4 4.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain TPR_15 PF13429.6 ETS80566.1 - 0.028 13.7 15.3 0.24 10.6 0.5 4.5 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 ETS80566.1 - 0.077 12.7 9.0 3.8 7.2 0.1 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat-like domain TEX29 PF15839.5 ETS80566.1 - 0.11 13.2 1.7 17 6.1 0.2 3.2 2 1 1 3 3 3 0 Testis-expressed sequence 29 protein TPR_17 PF13431.6 ETS80566.1 - 0.13 12.7 7.5 75 4.0 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS80566.1 - 0.14 11.5 4.9 1.6 8.0 1.6 3.8 3 1 0 3 3 3 0 MalT-like TPR region MIT PF04212.18 ETS80566.1 - 0.19 11.8 3.7 27 4.9 0.0 4.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 ETS80566.1 - 0.29 11.5 6.7 3.2 8.2 0.2 4.2 5 1 0 5 5 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ETS80566.1 - 0.98 9.5 6.1 82 3.4 0.0 4.8 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF572 PF04502.13 ETS80567.1 - 4.6e-68 230.3 9.3 7e-68 229.7 9.3 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF572) TF_Zn_Ribbon PF08271.12 ETS80567.1 - 0.011 15.2 1.4 0.011 15.2 1.4 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding FmiP_Thoc5 PF09766.9 ETS80567.1 - 2.8 7.1 8.3 1.1 8.5 6.0 1.4 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 GCP_N_terminal PF17681.1 ETS80568.1 - 4.4e-40 138.2 0.0 7.4e-40 137.5 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ETS80568.1 - 9.2e-23 81.2 1.4 9.2e-23 81.2 1.4 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 ETS80568.1 - 0.00013 20.5 0.1 0.00024 19.6 0.1 1.4 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Glyco_transf_15 PF01793.16 ETS80569.1 - 8.9e-115 383.4 8.4 1.1e-114 383.1 8.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase WD40 PF00400.32 ETS80570.1 - 8.8e-22 77.0 6.1 0.00015 22.5 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS80570.1 - 1.1e-10 41.7 0.0 0.03 14.6 0.0 5.5 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 ETS80570.1 - 0.00082 19.4 0.0 4.4 7.4 0.0 3.7 4 0 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region DUF5046 PF16465.5 ETS80570.1 - 0.0052 16.3 0.0 0.015 14.8 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5046) Nup160 PF11715.8 ETS80570.1 - 0.015 14.0 0.4 0.23 10.1 0.1 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 ETS80570.1 - 0.024 14.0 0.0 0.37 10.1 0.0 2.6 3 1 1 4 4 4 0 WD40-like domain PQQ PF01011.21 ETS80570.1 - 0.11 12.5 0.8 44 4.2 0.0 4.2 5 0 0 5 5 5 0 PQQ enzyme repeat Pet127 PF08634.10 ETS80571.1 - 3.5e-118 394.0 1.7 6.8e-118 393.0 1.7 1.5 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Pkinase PF00069.25 ETS80572.1 - 1.5e-11 44.2 0.0 2.9e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS80572.1 - 1.8e-09 37.3 0.0 3.5e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Uteroglobin PF01099.17 ETS80573.1 - 0.031 14.6 0.0 0.38 11.1 0.0 2.4 2 0 0 2 2 2 0 Uteroglobin family Peptidase_S78 PF04586.17 ETS80573.1 - 0.18 12.0 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Caudovirus prohead serine protease ATG101 PF07855.12 ETS80574.1 - 8.9e-54 181.7 0.1 1.1e-53 181.4 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Mo-co_dimer PF03404.16 ETS80574.1 - 0.026 14.6 3.2 0.17 11.9 3.2 2.0 1 1 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Peroxin-3 PF04882.12 ETS80575.1 - 1.8e-170 568.0 1.3 2.2e-170 567.7 1.3 1.1 1 0 0 1 1 1 1 Peroxin-3 Plasmodium_Vir PF05795.11 ETS80575.1 - 0.094 12.1 1.3 9.8 5.5 0.0 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Sybindin PF04099.12 ETS80576.1 - 2e-21 76.4 0.0 2.7e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family DUF3682 PF12446.8 ETS80577.1 - 0.0054 17.2 3.4 0.006 17.1 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3682) Pkinase PF00069.25 ETS80578.1 - 3.4e-57 193.8 0.1 1.5e-51 175.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS80578.1 - 2e-34 119.1 0.0 2.4e-33 115.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS80578.1 - 6.3e-09 35.6 0.0 1.8e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ETS80578.1 - 0.00022 21.3 0.1 0.00048 20.1 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ETS80578.1 - 0.00037 19.4 0.1 0.00037 19.4 0.1 2.0 3 1 0 3 3 3 1 Fungal protein kinase Presenilin PF01080.17 ETS80578.1 - 3.2 6.4 3.4 0.96 8.1 0.4 1.5 2 0 0 2 2 2 0 Presenilin DOT1 PF08123.13 ETS80579.1 - 7.8e-66 221.5 0.0 1.2e-65 220.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 ETS80579.1 - 0.063 13.1 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain AATF-Che1 PF13339.6 ETS80579.1 - 1.4 9.6 4.2 2 9.1 0.5 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor ATG16 PF08614.11 ETS80580.1 - 4.4e-48 164.2 21.9 5e-48 164.0 21.9 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 ETS80580.1 - 0.00017 21.1 12.4 0.00022 20.8 12.4 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 Med26 PF08711.11 ETS80580.1 - 0.26 11.3 2.6 1.5 8.9 0.3 2.9 3 0 0 3 3 3 0 TFIIS helical bundle-like domain bZIP_1 PF00170.21 ETS80580.1 - 0.48 10.6 16.0 1.2 9.3 0.1 3.9 2 1 2 4 4 4 0 bZIP transcription factor APG6_N PF17675.1 ETS80580.1 - 1 9.9 22.4 0.28 11.7 6.2 3.1 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF3138 PF11336.8 ETS80580.1 - 1.7 7.1 5.3 2.3 6.7 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) p450 PF00067.22 ETS80581.1 - 2.6e-56 191.3 0.0 3.5e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CAP PF00188.26 ETS80583.1 - 0.027 15.3 0.1 0.071 14.0 0.1 1.8 1 0 0 1 1 1 0 Cysteine-rich secretory protein family Mid2 PF04478.12 ETS80583.1 - 0.06 13.2 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.10 ETS80583.1 - 2.9 7.4 4.6 5.3 6.5 4.6 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ribosomal_S7e PF01251.18 ETS80584.1 - 1.1e-80 269.8 0.1 1.3e-80 269.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.13 ETS80585.1 - 8.9e-141 469.9 0.5 4.4e-108 362.1 0.0 2.0 1 1 1 2 2 2 2 Dynactin p62 family Dynactin_p62 PF05502.13 ETS80586.1 - 7.3e-24 84.4 5.8 9.6e-24 84.0 5.8 1.1 1 0 0 1 1 1 1 Dynactin p62 family Mu-like_Com PF10122.9 ETS80586.1 - 0.024 14.1 6.4 2.3 7.7 2.2 2.8 2 1 1 3 3 3 0 Mu-like prophage protein Com zf-B_box PF00643.24 ETS80586.1 - 1 9.6 9.8 0.21 11.8 4.3 2.3 1 1 1 2 2 2 0 B-box zinc finger Amidase PF01425.21 ETS80588.1 - 1.9e-84 284.2 0.3 2.5e-84 283.9 0.3 1.1 1 0 0 1 1 1 1 Amidase UL42 PF17638.2 ETS80589.1 - 0.048 13.6 1.9 0.054 13.5 1.9 1.2 1 0 0 1 1 1 0 HCMV UL42 EBP PF05241.12 ETS80590.1 - 1.2 8.6 9.0 5 6.6 9.0 2.0 1 1 0 1 1 1 0 Emopamil binding protein Zn_clus PF00172.18 ETS80591.1 - 0.00036 20.6 13.1 0.00066 19.7 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_8 PF13450.6 ETS80592.1 - 3.3e-10 40.1 0.0 7.5e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ETS80592.1 - 6.4e-10 39.0 0.9 1.1e-09 38.2 0.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS80592.1 - 4.7e-07 29.3 0.1 7.7e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS80592.1 - 6.5e-06 25.5 2.7 1e-05 24.9 2.7 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS80592.1 - 1.6e-05 24.6 3.5 2.1e-05 24.3 2.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ETS80592.1 - 1.9e-05 24.2 0.0 2.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 ETS80592.1 - 6.5e-05 22.3 0.1 0.0001 21.6 0.1 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 ETS80592.1 - 0.00015 20.6 0.7 0.00022 20.0 0.7 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 ETS80592.1 - 0.00019 20.8 0.2 0.00029 20.2 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS80592.1 - 0.00039 20.9 0.2 0.00071 20.1 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS80592.1 - 0.0017 17.7 0.7 0.0032 16.8 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 ETS80592.1 - 0.016 14.3 0.2 0.022 13.9 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 ETS80592.1 - 0.097 13.1 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding TPR_12 PF13424.6 ETS80593.1 - 4.3e-06 26.9 1.6 4.3e-06 26.9 1.6 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat DOG1 PF14144.6 ETS80593.1 - 0.026 14.7 0.0 0.18 12.1 0.0 2.5 2 0 0 2 2 2 0 Seed dormancy control TPR_10 PF13374.6 ETS80593.1 - 0.034 14.0 0.2 0.034 14.0 0.2 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 ETS80593.1 - 0.038 14.1 0.1 0.038 14.1 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 ETS80593.1 - 0.14 12.5 7.2 0.29 11.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 ETS80593.1 - 0.2 11.6 6.0 0.7 9.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 ETS80593.1 - 2.1 9.4 8.8 1.4 9.9 0.2 4.4 2 1 2 4 4 4 0 Tetratricopeptide repeat HET PF06985.11 ETS80593.1 - 6.3 7.1 8.5 1.1 9.7 0.8 3.0 3 1 0 3 3 3 0 Heterokaryon incompatibility protein (HET) TPR_7 PF13176.6 ETS80593.1 - 6.4 7.0 7.7 0.43 10.7 0.2 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.6 ETS80596.1 - 0.0049 17.6 4.7 2.7 9.0 0.1 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ETS80596.1 - 0.012 16.0 4.8 0.18 12.3 0.2 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4014 PF13198.6 ETS80597.1 - 0.0036 17.7 1.0 0.87 10.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4014) SPW PF03779.14 ETS80597.1 - 8.6 6.0 8.0 0.41 10.3 1.7 2.1 2 0 0 2 2 2 0 SPW repeat Ribosomal_L1 PF00687.21 ETS80598.1 - 9.5e-45 152.8 0.1 1.1e-44 152.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family NUDIX PF00293.28 ETS80599.1 - 2.1e-17 63.4 0.0 4e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 ETS80599.1 - 1.5e-13 51.2 0.0 3.8e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 ETS80599.1 - 4.5e-07 29.4 0.6 8.8e-07 28.5 0.6 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain RabGAP-TBC PF00566.18 ETS80600.1 - 2.7e-27 95.8 0.1 4.1e-27 95.2 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FYVE PF01363.21 ETS80602.1 - 0.012 15.7 1.2 0.023 14.8 1.2 1.4 1 0 0 1 1 1 0 FYVE zinc finger Zn_Tnp_IS91 PF14319.6 ETS80602.1 - 0.18 11.8 2.5 0.36 10.9 2.5 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-B_box PF00643.24 ETS80602.1 - 0.36 11.0 2.8 0.59 10.3 2.8 1.3 1 0 0 1 1 1 0 B-box zinc finger Cytochrom_c3_2 PF14537.6 ETS80602.1 - 0.56 10.7 3.2 1.4 9.4 3.2 1.6 1 0 0 1 1 1 0 Cytochrome c3 DZR PF12773.7 ETS80602.1 - 4.4 7.4 6.7 2.3 8.3 3.5 1.9 2 0 0 2 2 2 0 Double zinc ribbon MFS_1 PF07690.16 ETS80603.1 - 1.8e-41 142.3 47.2 3.7e-41 141.2 47.2 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS80603.1 - 4.8e-13 48.8 5.8 4.8e-13 48.8 5.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter DUF4407 PF14362.6 ETS80603.1 - 1.1 8.6 6.1 0.84 8.9 3.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DHFR_1 PF00186.19 ETS80604.1 - 3.6e-29 101.5 0.0 1.2e-28 99.9 0.0 1.9 1 1 0 1 1 1 1 Dihydrofolate reductase Phage-tail_2 PF09096.10 ETS80604.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Baseplate structural protein, domain 2 Pkinase PF00069.25 ETS80605.1 - 3.8e-31 108.4 0.0 1.7e-29 103.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS80605.1 - 9.3e-11 41.5 0.1 0.00052 19.4 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 ETS80605.1 - 0.00038 19.9 0.1 0.00076 18.9 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family IBR PF01485.21 ETS80606.1 - 3.4e-11 43.2 20.9 5.2e-11 42.6 0.5 3.7 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 ETS80606.1 - 0.016 15.4 1.3 0.016 15.4 1.3 3.2 5 0 0 5 5 5 0 AN1-like Zinc finger BssB_TutG PF18512.1 ETS80606.1 - 0.044 13.7 1.6 0.11 12.4 1.6 1.6 1 0 0 1 1 1 0 Benzylsuccinate synthase beta subunit DDHD PF02862.17 ETS80606.1 - 0.27 11.4 1.1 1 9.4 0.2 2.1 2 0 0 2 2 2 0 DDHD domain MCM_OB PF17207.3 ETS80606.1 - 5.3 6.9 9.2 0.14 12.0 2.6 1.7 2 0 0 2 2 2 0 MCM OB domain Ank_2 PF12796.7 ETS80608.1 - 2.5e-69 229.9 0.0 3e-16 59.8 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS80608.1 - 2.3e-54 181.1 1.1 5.2e-12 46.0 0.0 5.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS80608.1 - 7.5e-47 156.8 0.7 5e-13 49.0 0.0 6.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 ETS80608.1 - 7.3e-44 146.4 7.1 2.9e-09 37.0 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 ETS80608.1 - 4.8e-42 137.1 0.1 2.8e-07 30.3 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat TPR_11 PF13414.6 ETS80608.1 - 8.5e-06 25.4 7.5 0.28 10.9 0.4 5.0 4 0 0 4 4 4 2 TPR repeat TPR_12 PF13424.6 ETS80608.1 - 1.7e-05 25.0 13.9 2.7 8.3 0.3 7.4 5 3 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 ETS80608.1 - 2.9e-05 23.9 9.0 0.85 10.0 0.3 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 ETS80608.1 - 0.00014 21.6 17.3 0.17 11.8 1.3 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 ETS80608.1 - 0.00043 20.2 15.8 0.8 10.0 0.8 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 ETS80608.1 - 0.00059 19.7 7.9 0.56 10.4 0.2 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TOM20_plant PF06552.12 ETS80608.1 - 0.0009 19.0 0.1 0.0087 15.8 0.1 2.2 1 1 0 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_1 PF00515.28 ETS80608.1 - 0.0024 17.6 17.5 0.25 11.2 0.5 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat Sel1 PF08238.12 ETS80608.1 - 0.0088 16.7 1.2 7.7 7.4 0.0 3.6 2 0 0 2 2 2 1 Sel1 repeat TPR_14 PF13428.6 ETS80608.1 - 0.05 14.4 6.8 6.9 7.8 0.1 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF4071 PF13281.6 ETS80608.1 - 0.12 11.4 0.4 4.9 6.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4071) TPR_19 PF14559.6 ETS80608.1 - 0.13 12.8 6.8 41 4.8 1.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS80608.1 - 0.14 11.5 0.8 0.91 8.8 0.0 2.5 2 1 1 3 3 3 0 MalT-like TPR region Vta1_C PF18097.1 ETS80608.1 - 0.2 11.4 2.3 5.4 6.8 0.0 3.3 3 0 0 3 3 3 0 Vta1 C-terminal domain TPR_16 PF13432.6 ETS80608.1 - 3 8.6 12.4 27 5.5 3.4 5.5 7 1 0 7 7 4 0 Tetratricopeptide repeat HET PF06985.11 ETS80609.1 - 8.5e-17 61.9 1.8 1.5e-16 61.1 1.8 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PhyH PF05721.13 ETS80610.1 - 0.017 15.4 0.2 0.12 12.6 0.2 2.1 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Hydrolase_6 PF13344.6 ETS80611.1 - 5.5e-28 97.0 0.0 9e-28 96.4 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ETS80611.1 - 2.7e-16 59.4 0.0 7.3e-16 58.0 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 ETS80611.1 - 3.1e-10 40.7 0.0 0.00036 20.9 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ETS80611.1 - 2.8e-06 27.5 0.0 0.058 13.5 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase LAGLIDADG_3 PF14528.6 ETS80611.1 - 0.048 14.0 0.1 0.084 13.2 0.1 1.4 1 0 0 1 1 1 0 LAGLIDADG-like domain Glucosamine_iso PF01182.20 ETS80612.1 - 6.4e-68 229.0 0.0 7.3e-68 228.8 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ubiq_cyt_C_chap PF03981.12 ETS80613.1 - 3.2e-38 131.0 0.1 5.1e-38 130.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone ketoacyl-synt PF00109.26 ETS80614.1 - 1.5e-61 208.2 2.8 3.2e-60 203.8 0.4 2.1 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ETS80614.1 - 1.8e-29 102.2 1.0 2e-27 95.5 0.4 2.2 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 ETS80614.1 - 0.0001 21.8 0.3 0.003 17.0 0.2 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 ETS80614.1 - 0.14 12.6 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Thiolase_C PF02803.18 ETS80614.1 - 0.16 11.6 4.7 2.2 8.0 0.3 3.5 2 2 0 2 2 2 0 Thiolase, C-terminal domain PSI_PSAK PF01241.18 ETS80614.1 - 0.68 10.0 4.3 6.7 6.8 0.1 3.2 2 1 1 3 3 3 0 Photosystem I psaG / psaK OPT PF03169.15 ETS80615.1 - 2.8e-183 610.9 56.3 3.2e-183 610.7 56.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FAD_binding_3 PF01494.19 ETS80616.1 - 8.1e-15 54.9 0.4 1.2e-13 51.0 0.1 2.6 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS80616.1 - 3e-08 33.3 0.3 6.5e-08 32.2 0.3 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS80616.1 - 1.5e-06 28.4 0.4 4.7e-06 26.7 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS80616.1 - 0.0055 15.8 3.6 0.011 14.8 2.6 1.9 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 ETS80616.1 - 0.0056 15.8 0.6 0.0056 15.8 0.6 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ETS80616.1 - 0.0063 15.8 0.8 0.0063 15.8 0.8 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 ETS80616.1 - 0.01 15.2 1.3 0.015 14.6 1.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 ETS80616.1 - 0.026 14.1 5.5 0.14 11.7 3.3 2.2 1 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS80616.1 - 0.029 14.9 1.9 0.18 12.4 1.6 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ETS80616.1 - 0.042 13.1 0.2 0.62 9.3 0.1 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 ETS80616.1 - 0.072 11.8 1.7 0.098 11.3 1.0 1.5 2 0 0 2 2 2 0 HI0933-like protein COX6C PF02937.15 ETS80616.1 - 0.13 12.4 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc Trp_halogenase PF04820.14 ETS80616.1 - 0.14 11.0 3.2 12 4.6 0.7 3.0 3 0 0 3 3 3 0 Tryptophan halogenase 3HCDH_N PF02737.18 ETS80616.1 - 0.17 11.8 0.6 0.29 11.0 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WD40 PF00400.32 ETS80617.1 - 4.7e-31 106.4 13.0 1.2e-06 29.1 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS80617.1 - 1.4e-09 38.1 0.6 0.0048 17.2 0.0 4.9 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 ETS80617.1 - 2.5e-09 36.9 0.1 4.6e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS80617.1 - 4.2e-07 29.7 0.0 8.4e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 ETS80617.1 - 0.00016 20.4 0.3 1.4 7.5 0.0 3.7 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Frtz PF11768.8 ETS80617.1 - 0.032 12.6 0.0 0.41 8.9 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 ETS80617.1 - 0.042 12.4 0.1 0.077 11.5 0.1 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain PQQ PF01011.21 ETS80617.1 - 0.13 12.3 0.3 7.7 6.6 0.0 3.9 4 0 0 4 4 4 0 PQQ enzyme repeat SRI PF08236.11 ETS80619.1 - 6.1e-22 77.6 13.1 1.9e-21 76.0 13.1 1.9 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 ETS80619.1 - 4e-17 63.1 0.4 4e-17 63.1 0.4 3.4 3 2 0 3 3 3 1 SET domain AWS PF17907.1 ETS80619.1 - 5.7e-12 45.5 12.4 5.7e-12 45.5 12.4 2.6 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 ETS80619.1 - 5.2e-05 23.2 0.1 0.00015 21.7 0.1 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WW PF00397.26 ETS80619.1 - 0.00083 19.4 2.1 0.0019 18.2 2.1 1.7 1 0 0 1 1 1 1 WW domain Pkinase PF00069.25 ETS80620.1 - 2.1e-58 197.8 0.0 2.9e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS80620.1 - 5.5e-21 75.0 0.0 8.4e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS80620.1 - 2e-06 27.4 0.0 3.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ETS80620.1 - 3.8e-05 22.8 0.0 6.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ETS80620.1 - 0.00027 20.3 0.1 0.00051 19.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ETS80620.1 - 0.0017 18.0 0.1 0.0036 16.9 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 ETS80620.1 - 0.0026 17.7 0.8 0.023 14.6 0.5 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ETS80620.1 - 0.0042 15.9 0.7 0.0093 14.8 0.7 1.6 1 1 0 1 1 1 1 Fungal protein kinase TMEM154 PF15102.6 ETS80621.1 - 0.004 17.1 0.0 0.021 14.8 0.0 2.1 2 0 0 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.6 ETS80621.1 - 0.0055 17.5 0.0 0.0055 17.5 0.0 2.7 2 1 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.6 ETS80621.1 - 0.016 14.9 0.0 0.016 14.9 0.0 3.1 2 1 0 3 3 3 0 FAM176 family Tweety PF04906.13 ETS80621.1 - 0.021 13.5 0.0 0.031 13.0 0.0 1.1 1 0 0 1 1 1 0 Tweety Adeno_E3_CR2 PF02439.15 ETS80621.1 - 0.05 13.4 1.7 0.1 12.4 1.7 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SARAF PF06682.12 ETS80621.1 - 0.069 12.8 8.1 0.099 12.3 5.9 2.2 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis FAM163 PF15069.6 ETS80621.1 - 0.11 12.9 1.0 0.5 10.8 0.2 2.5 2 1 0 2 2 2 0 FAM163 family DUF4834 PF16118.5 ETS80621.1 - 0.16 12.9 0.0 0.16 12.9 0.0 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) Neur_chan_memb PF02932.16 ETS80621.1 - 0.17 11.9 2.4 0.33 11.0 2.4 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Syndecan PF01034.20 ETS80621.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DUF5385 PF17359.2 ETS80621.1 - 0.36 10.3 1.4 0.88 9.1 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5385) CbtA PF09490.10 ETS80621.1 - 0.38 10.5 0.1 0.38 10.5 0.1 1.6 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) DUF2615 PF11027.8 ETS80621.1 - 0.42 10.8 0.0 0.42 10.8 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2615) NicO PF03824.16 ETS80621.1 - 3.6 6.8 5.8 0.31 10.3 0.3 1.8 2 0 0 2 2 2 0 High-affinity nickel-transport protein Macoilin PF09726.9 ETS80621.1 - 3.9 5.9 11.2 6 5.3 11.2 1.3 1 0 0 1 1 1 0 Macoilin family His_Phos_1 PF00300.22 ETS80622.1 - 1e-19 71.0 0.0 7.1e-18 65.0 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4592 PF15262.6 ETS80623.1 - 3.4 8.4 10.6 0.29 11.8 3.6 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4592) Iwr1 PF08574.10 ETS80624.1 - 6.9e-15 55.8 12.2 6.9e-15 55.8 12.2 3.5 4 1 1 5 5 5 1 Transcription factor Iwr1 AMPK1_CBM PF16561.5 ETS80625.1 - 1.1e-06 28.7 0.2 1.9e-06 28.0 0.2 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Pyridoxal_deC PF00282.19 ETS80627.1 - 2.4e-19 69.3 0.0 1e-09 37.7 0.0 3.2 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 ETS80627.1 - 0.2 10.9 0.0 0.51 9.6 0.0 1.6 1 0 0 1 1 1 0 Beta-eliminating lyase Fungal_trans_2 PF11951.8 ETS80629.1 - 0.00022 20.1 1.0 0.00047 19.1 1.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sorb PF02208.16 ETS80629.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Sorbin homologous domain Ank_2 PF12796.7 ETS80630.1 - 3.5e-34 117.2 0.5 1.6e-09 38.2 0.0 5.5 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS80630.1 - 7.7e-25 87.0 7.1 1.6e-07 31.7 0.0 7.4 4 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS80630.1 - 4.4e-22 77.9 3.6 1.6e-10 41.0 0.1 5.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 ETS80630.1 - 2.3e-18 65.7 10.9 0.00085 19.7 0.0 8.5 8 1 0 8 8 8 3 Ankyrin repeat Ank_3 PF13606.6 ETS80630.1 - 5.6e-14 50.9 4.7 0.049 14.2 0.0 9.0 9 0 0 9 9 9 2 Ankyrin repeat NACHT PF05729.12 ETS80630.1 - 2.3e-05 24.4 0.2 0.00014 21.8 0.1 2.4 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 ETS80630.1 - 2.3e-05 24.7 0.0 6.8e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS80630.1 - 0.00013 22.4 0.1 0.00065 20.1 0.1 2.2 2 0 0 2 2 1 1 AAA ATPase domain RNA_helicase PF00910.22 ETS80630.1 - 0.0041 17.5 0.0 0.0099 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Ploopntkinase3 PF18751.1 ETS80630.1 - 0.016 15.2 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 ETS80630.1 - 0.026 15.1 0.0 0.06 13.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 ETS80630.1 - 0.026 15.1 0.0 0.13 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ETS80630.1 - 0.086 12.9 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 ETS80630.1 - 0.13 12.4 0.0 0.45 10.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain UPF0182 PF03699.13 ETS80633.1 - 0.35 8.9 6.0 0.51 8.4 6.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF3433 PF11915.8 ETS80635.1 - 2e-16 60.2 24.1 4.4e-12 46.3 0.4 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) SDF PF00375.18 ETS80635.1 - 0.019 14.0 0.0 0.043 12.8 0.0 1.6 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family AAA PF00004.29 ETS80636.1 - 7.7e-22 78.1 0.0 3.8e-10 40.3 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 ETS80636.1 - 6.4e-09 35.9 1.9 2.2e-06 27.7 0.0 4.3 4 0 0 4 4 3 1 AAA lid domain AAA_30 PF13604.6 ETS80636.1 - 9.5e-09 35.2 0.0 0.00034 20.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ETS80636.1 - 1.1e-07 32.0 0.1 0.0011 19.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ETS80636.1 - 3.2e-07 30.7 2.6 0.21 11.9 0.1 5.3 5 1 0 5 5 4 2 AAA domain AAA_16 PF13191.6 ETS80636.1 - 1.2e-06 29.0 1.3 0.078 13.4 0.0 4.5 4 1 0 4 4 4 2 AAA ATPase domain AAA_18 PF13238.6 ETS80636.1 - 6e-06 26.8 0.1 0.19 12.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 ETS80636.1 - 3e-05 23.5 0.4 0.087 12.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 ETS80636.1 - 6.5e-05 22.7 0.1 0.33 10.7 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 ETS80636.1 - 7.4e-05 22.9 0.5 0.47 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 ETS80636.1 - 0.00013 22.4 0.6 2.2 8.6 0.1 3.5 2 1 1 3 3 3 2 AAA domain AAA_17 PF13207.6 ETS80636.1 - 0.00013 22.4 0.3 0.26 11.7 0.1 3.6 3 1 0 3 3 2 1 AAA domain Importin_rep_6 PF18829.1 ETS80636.1 - 0.00085 19.4 0.3 0.89 9.7 0.0 3.5 2 1 1 3 3 3 1 Importin repeat 6 AAA_24 PF13479.6 ETS80636.1 - 0.00091 19.0 0.4 1.3 8.7 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 ETS80636.1 - 0.0011 18.8 0.1 2.5 7.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 ETS80636.1 - 0.0014 18.9 0.0 2.1 8.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 ETS80636.1 - 0.0063 16.3 0.0 3.4 7.4 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 ETS80636.1 - 0.0082 15.4 0.3 0.082 12.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.26 ETS80636.1 - 0.011 15.5 0.1 1.9 8.2 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 ETS80636.1 - 0.012 15.5 0.2 0.26 11.2 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 ETS80636.1 - 0.013 15.7 0.1 5.2 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 ETS80636.1 - 0.022 14.5 0.1 6.8 6.4 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 ETS80636.1 - 0.063 13.3 0.2 0.74 9.8 0.0 2.6 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 ETS80636.1 - 0.066 13.1 0.1 8 6.3 0.0 2.6 2 0 0 2 2 2 0 NTPase PhoH PF02562.16 ETS80636.1 - 0.073 12.5 0.2 14 5.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Torsin PF06309.11 ETS80636.1 - 0.092 12.8 0.1 2.5 8.2 0.0 2.8 3 0 0 3 3 2 0 Torsin VirE PF05272.11 ETS80636.1 - 0.11 12.2 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E ABC_tran PF00005.27 ETS80636.1 - 0.11 13.0 0.0 9.3 6.8 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 ETS80636.1 - 0.17 11.4 0.2 3.9 7.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region SRP54 PF00448.22 ETS80636.1 - 0.31 10.6 1.0 19 4.8 0.0 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain HET PF06985.11 ETS80637.1 - 3.8e-26 92.2 2.7 1.1e-24 87.5 2.7 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_S66 PF02016.15 ETS80638.1 - 5.5e-28 97.5 0.0 8.6e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 ETS80638.1 - 4.7e-23 82.1 0.0 8.1e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain GMC_oxred_C PF05199.13 ETS80639.1 - 8.9e-17 62.0 0.2 4.5e-16 59.7 0.2 2.2 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 ETS80639.1 - 8.7e-07 28.6 0.0 3.1e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_3 PF01494.19 ETS80639.1 - 4.1e-06 26.3 0.2 6.4e-06 25.6 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 ETS80639.1 - 0.02 15.4 0.0 0.046 14.2 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 ETS80639.1 - 0.046 13.0 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS80639.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 ETS80639.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 ETS80639.1 - 0.18 12.0 0.2 0.47 10.7 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DEAD PF00270.29 ETS80641.1 - 1.2e-28 100.0 0.0 2e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS80641.1 - 3.1e-19 69.3 0.0 2.6e-18 66.4 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS80641.1 - 0.0001 22.4 0.0 0.00036 20.6 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit TIP41 PF04176.13 ETS80643.1 - 8.5e-67 223.9 0.1 1.1e-66 223.6 0.1 1.1 1 0 0 1 1 1 1 TIP41-like family Nsp3_PL2pro PF12124.8 ETS80643.1 - 0.29 10.9 1.6 8.9 6.2 0.8 3.1 1 1 2 3 3 3 0 Coronavirus polyprotein cleavage domain zf-C2H2 PF00096.26 ETS80644.1 - 4.4e-07 30.0 17.8 1.9e-05 24.9 3.8 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ETS80644.1 - 2.1e-05 24.7 6.9 4e-05 23.8 3.8 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ETS80644.1 - 4.2e-05 24.0 2.3 4.2e-05 24.0 2.3 3.6 4 0 0 4 4 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ETS80644.1 - 0.0015 18.8 1.0 0.0015 18.8 1.0 1.8 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ETS80644.1 - 0.0018 18.2 1.8 0.0018 18.2 1.8 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger FOXP-CC PF16159.5 ETS80644.1 - 0.028 15.0 6.8 0.13 12.9 0.3 3.1 1 1 2 3 3 3 0 FOXP coiled-coil domain Malectin_like PF12819.7 ETS80644.1 - 0.058 12.6 0.2 0.092 11.9 0.2 1.2 1 0 0 1 1 1 0 Malectin-like domain zf-TRAF PF02176.18 ETS80644.1 - 0.069 13.8 3.1 0.14 12.8 3.1 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_8 PF15909.5 ETS80644.1 - 0.088 13.1 4.7 0.16 12.3 3.6 2.0 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-met PF12874.7 ETS80644.1 - 0.13 12.7 0.7 0.35 11.3 0.7 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 ETS80644.1 - 0.6 10.5 4.9 0.61 10.5 2.7 2.2 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF629 PF04780.12 ETS80644.1 - 0.63 8.5 3.6 1.5 7.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2HE PF16278.5 ETS80644.1 - 2.3 8.7 4.5 5 7.6 4.4 1.7 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 ETS80644.1 - 3.7 7.6 5.3 1 9.3 1.4 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type SET PF00856.28 ETS80645.1 - 4.2e-11 43.5 0.0 1e-10 42.3 0.0 1.7 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 ETS80645.1 - 1.9 8.6 13.0 0.16 12.0 6.6 2.5 2 0 0 2 2 2 0 MYND finger CPP1-like PF11833.8 ETS80646.1 - 0.11 12.2 1.4 4.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PTS_2-RNA PF01885.16 ETS80647.1 - 1.6e-65 220.5 0.0 2e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family CDT1 PF08839.11 ETS80647.1 - 0.032 14.5 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 DNA replication factor CDT1 like Sugar_tr PF00083.24 ETS80649.1 - 1.5e-101 340.5 21.0 1.9e-101 340.2 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS80649.1 - 1.1e-22 80.4 32.7 1.8e-20 73.2 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS80649.1 - 0.00017 20.2 0.5 0.00017 20.2 0.5 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 ETS80649.1 - 0.47 9.2 13.2 0.027 13.3 1.6 3.3 3 1 0 3 3 3 0 MFS_1 like family Med21 PF11221.8 ETS80651.1 - 0.046 14.0 0.5 0.13 12.5 0.2 1.8 2 0 0 2 2 2 0 Subunit 21 of Mediator complex PH PF00169.29 ETS80653.1 - 7.8e-05 23.1 0.1 0.00018 22.0 0.1 1.5 1 0 0 1 1 1 1 PH domain RmlD_sub_bind PF04321.17 ETS80654.1 - 6.6e-55 186.2 0.0 8.1e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 ETS80654.1 - 3.8e-21 75.7 0.0 4.8e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ETS80654.1 - 3.6e-10 39.4 0.0 1.9e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 ETS80654.1 - 3.4e-09 36.6 0.0 2.4e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ETS80654.1 - 3.7e-07 29.6 0.1 0.00063 19.0 0.0 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ETS80654.1 - 2.9e-06 26.5 0.0 1.2e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 ETS80654.1 - 0.0018 17.9 0.1 0.059 12.9 0.1 2.4 2 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 ETS80654.1 - 0.032 14.1 0.0 0.071 13.0 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H-binding adh_short PF00106.25 ETS80654.1 - 0.038 13.4 0.1 0.064 12.7 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 ETS80654.1 - 0.098 12.8 0.1 0.22 11.6 0.1 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 ETS80654.1 - 0.16 11.9 0.0 3.8 7.4 0.0 2.3 2 0 0 2 2 2 0 KR domain FAD_binding_4 PF01565.23 ETS80656.1 - 7.1e-22 77.6 2.9 7.1e-22 77.6 2.9 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 ETS80656.1 - 1.3e-07 31.6 0.3 1.3e-07 31.6 0.3 2.3 3 0 0 3 3 3 1 Berberine and berberine like Cytokin-bind PF09265.10 ETS80656.1 - 0.16 11.3 0.2 0.29 10.5 0.2 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding AA_permease_2 PF13520.6 ETS80657.1 - 6.6e-38 130.6 44.0 8.2e-38 130.3 44.0 1.0 1 0 0 1 1 1 1 Amino acid permease ILVD_EDD PF00920.21 ETS80658.1 - 3.3e-78 263.6 0.2 3.9e-78 263.3 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family ApbA PF02558.16 ETS80658.1 - 0.022 14.4 1.0 0.037 13.7 0.3 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glycos_transf_3 PF00591.21 ETS80658.1 - 0.054 13.1 0.1 0.76 9.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family, a/b domain Aminotran_4 PF01063.19 ETS80659.1 - 4.9e-15 56.0 0.0 6.4e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV RTA1 PF04479.13 ETS80660.1 - 1.5e-51 175.0 7.3 1.5e-51 175.0 7.3 1.6 2 0 0 2 2 2 1 RTA1 like protein MARVEL PF01284.23 ETS80660.1 - 0.1 12.6 15.8 1.5 8.9 1.4 2.9 2 1 0 2 2 2 0 Membrane-associating domain YqjK PF13997.6 ETS80660.1 - 0.16 12.2 1.0 1.6 9.0 0.1 2.4 2 0 0 2 2 2 0 YqjK-like protein His_Phos_1 PF00300.22 ETS80661.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) Peptidase_C37 PF05416.12 ETS80661.1 - 2.9 6.3 8.3 5.6 5.3 8.3 1.4 1 0 0 1 1 1 0 Southampton virus-type processing peptidase B-block_TFIIIC PF04182.12 ETS80662.1 - 2.3e-12 46.9 0.0 4.8e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC UQ_con PF00179.26 ETS80663.1 - 1.4e-17 63.6 0.0 2.4e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ETS80663.1 - 0.089 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 RWD domain UvsY PF11056.8 ETS80664.1 - 0.01 16.2 0.3 0.12 12.8 0.1 2.2 2 0 0 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY UBA_4 PF14555.6 ETS80664.1 - 0.026 14.3 0.1 0.067 13.0 0.1 1.8 1 0 0 1 1 1 0 UBA-like domain UIM PF02809.20 ETS80664.1 - 0.45 10.6 9.2 0.52 10.3 4.6 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif Rit1_C PF17184.4 ETS80665.1 - 1.4e-112 375.6 0.0 2e-112 375.1 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 ETS80665.1 - 2.1e-36 124.6 0.8 4.4e-36 123.5 0.3 1.8 2 0 0 2 2 2 1 Rit1 DUSP-like domain ODAM PF15424.6 ETS80665.1 - 0.046 13.3 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Odontogenic ameloblast-associated family DnaJ_C PF01556.18 ETS80666.1 - 5.6e-39 133.6 0.6 7.3e-39 133.2 0.6 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ETS80666.1 - 2.2e-27 95.0 3.1 3.4e-27 94.3 3.1 1.3 1 0 0 1 1 1 1 DnaJ domain UQ_con PF00179.26 ETS80667.1 - 3.9e-36 123.8 0.0 4.8e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rox3 PF08633.10 ETS80668.1 - 4e-64 216.7 0.3 4e-64 216.7 0.3 1.5 2 0 0 2 2 2 1 Rox3 mediator complex subunit T3SS_NleG PF06416.12 ETS80668.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Effector protein NleG PGAP1 PF07819.13 ETS80669.1 - 1.5e-05 24.9 0.0 2.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 ETS80669.1 - 2.5e-05 25.0 0.1 8.9e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS80669.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 ETS80669.1 - 0.0032 17.4 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 ETS80669.1 - 0.008 15.7 0.8 0.019 14.5 0.0 1.9 3 0 0 3 3 3 1 Putative serine esterase (DUF676) Thioesterase PF00975.20 ETS80669.1 - 0.014 15.5 0.0 0.014 15.5 0.0 2.0 3 0 0 3 3 3 0 Thioesterase domain Abhydrolase_1 PF00561.20 ETS80669.1 - 0.024 14.3 0.0 0.058 13.0 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 ETS80669.1 - 0.038 13.8 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.15 ETS80669.1 - 0.042 13.0 0.1 0.17 11.0 0.0 1.8 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase UPF0227 PF05728.12 ETS80669.1 - 0.063 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF900 PF05990.12 ETS80669.1 - 0.11 12.0 0.0 1.2 8.5 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Hep_59 PF07052.11 ETS80669.1 - 0.11 13.2 5.9 0.36 11.6 5.9 1.9 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 DUF2458 PF10454.9 ETS80669.1 - 0.66 9.6 6.1 2.3 7.8 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) OmpH PF03938.14 ETS80669.1 - 0.85 9.9 9.9 1.5 9.2 9.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Glyco_hydro_3_C PF01915.22 ETS80670.1 - 5.2e-43 147.4 0.0 2.5e-42 145.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS80670.1 - 3.4e-38 131.8 0.0 5.3e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS80670.1 - 2.9e-22 78.5 0.2 5.1e-22 77.8 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Peptidase_A2B PF12384.8 ETS80670.1 - 0.029 13.9 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Ty3 transposon peptidase CARDB PF07705.11 ETS80670.1 - 0.036 14.3 0.1 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 CARDB Lipase_3 PF01764.25 ETS80671.1 - 2.4e-34 118.2 0.1 4.9e-34 117.2 0.0 1.5 2 0 0 2 2 2 1 Lipase (class 3) Lipase3_N PF03893.16 ETS80671.1 - 0.0045 17.0 0.2 0.011 15.7 0.2 1.7 1 0 0 1 1 1 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 ETS80671.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS80671.1 - 0.067 13.8 2.3 0.071 13.7 0.7 1.7 1 1 0 2 2 2 0 Alpha/beta hydrolase family FMO-like PF00743.19 ETS80672.1 - 3e-23 82.0 0.1 1.9e-15 56.3 0.0 3.7 4 1 0 4 4 4 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ETS80672.1 - 4.7e-11 42.5 2.7 1e-05 25.0 0.2 4.0 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS80672.1 - 1.3e-10 41.0 1.8 4.1e-09 36.1 1.8 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS80672.1 - 3e-05 24.2 0.0 0.00013 22.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS80672.1 - 0.00073 19.5 7.2 0.021 14.8 4.3 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 ETS80672.1 - 0.003 16.9 0.2 0.057 12.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 ETS80672.1 - 0.0036 16.9 0.0 0.23 11.0 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 ETS80672.1 - 0.0054 15.9 0.9 0.16 11.1 0.7 3.0 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DJ-1_PfpI PF01965.24 ETS80672.1 - 0.13 12.0 0.0 4.4 7.1 0.0 2.2 2 0 0 2 2 2 0 DJ-1/PfpI family Pyr_redox PF00070.27 ETS80672.1 - 0.2 12.3 0.1 8.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AA_permease_2 PF13520.6 ETS80673.1 - 1.8e-58 198.4 44.4 2.3e-58 198.0 44.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS80673.1 - 2.6e-25 89.0 30.2 2.6e-25 89.0 30.2 2.1 2 0 0 2 2 2 1 Amino acid permease tRNA-synt_1 PF00133.22 ETS80674.1 - 3.4e-50 170.9 0.0 7e-20 70.8 0.1 6.2 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 ETS80674.1 - 3.3e-33 114.8 0.0 6e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 ETS80674.1 - 3.1e-29 101.9 2.6 9.9e-22 77.2 0.0 4.8 5 1 0 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 ETS80674.1 - 8.2e-13 48.6 0.1 1.7e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA PSRT PF07636.11 ETS80674.1 - 0.038 13.7 1.6 0.096 12.4 1.6 1.6 1 0 0 1 1 1 0 PSRT tRNA-synt_1e PF01406.19 ETS80674.1 - 0.04 13.3 0.0 4.6 6.5 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Zn-ribbon_8 PF09723.10 ETS80674.1 - 0.75 10.0 2.1 1.7 8.8 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Methyltransf_31 PF13847.6 ETS80675.1 - 4.7e-07 29.7 0.0 1.5e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmC_N PF17827.1 ETS80675.1 - 5.6e-07 30.1 0.1 1.7e-06 28.5 0.1 1.8 1 0 0 1 1 1 1 PrmC N-terminal domain MTS PF05175.14 ETS80675.1 - 3.7e-05 23.4 0.0 0.0012 18.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ETS80675.1 - 3.7e-05 24.4 0.0 0.00019 22.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS80675.1 - 0.0039 17.0 0.0 0.022 14.6 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 ETS80675.1 - 0.036 13.7 0.0 1.4 8.6 0.0 2.2 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.13 ETS80675.1 - 0.049 13.0 0.0 0.24 10.7 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 ETS80675.1 - 0.058 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family N6_Mtase PF02384.16 ETS80675.1 - 0.059 12.6 0.0 0.17 11.2 0.0 1.6 1 1 0 1 1 1 0 N-6 DNA Methylase Methyltransf_11 PF08241.12 ETS80675.1 - 0.062 14.0 0.0 0.23 12.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain AviRa PF11599.8 ETS80675.1 - 0.15 11.5 0.0 0.52 9.7 0.0 1.7 1 1 1 2 2 2 0 RRNA methyltransferase AviRa Suc_Fer-like PF06999.12 ETS80676.1 - 1.2e-60 204.7 0.0 1.5e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like FAD_binding_6 PF00970.24 ETS80677.1 - 3.5e-09 36.9 0.0 8e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ETS80677.1 - 2.6e-05 24.8 0.0 5.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ETS80677.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain MMACHC PF16690.5 ETS80677.1 - 0.042 13.5 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type C family Epimerase PF01370.21 ETS80678.1 - 2.4e-09 37.0 0.2 0.00054 19.5 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS80678.1 - 2.5e-07 30.7 0.1 4e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ETS80678.1 - 4.7e-05 22.5 0.1 0.0002 20.5 0.1 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 ETS80678.1 - 8.6e-05 22.2 0.1 0.00046 19.8 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 ETS80678.1 - 0.00013 21.4 0.0 0.0068 15.9 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 ETS80678.1 - 0.0019 18.5 0.1 0.0036 17.5 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 ETS80678.1 - 0.032 14.4 0.0 0.049 13.8 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 ETS80678.1 - 0.054 12.8 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 ETS80678.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 ETS80678.1 - 0.082 13.2 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 ETS80678.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Na_H_Exchanger PF00999.21 ETS80679.1 - 1.7e-61 208.1 21.0 2.3e-61 207.7 21.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CN_hydrolase PF00795.22 ETS80679.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase DUF543 PF04418.12 ETS80679.1 - 0.29 11.2 1.3 13 5.8 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Mito_carr PF00153.27 ETS80680.1 - 1.1e-59 198.3 1.9 3.2e-19 68.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 ETS80681.1 - 1e-32 111.7 0.0 7.3e-16 57.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 ETS80681.1 - 0.0004 20.0 1.3 0.089 12.5 0.1 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain CMV_1a_C PF12503.8 ETS80681.1 - 0.0048 16.9 0.2 0.32 11.0 0.1 2.3 2 0 0 2 2 2 1 Cucumber mosaic virus 1a protein C terminal RRM_7 PF16367.5 ETS80681.1 - 0.013 15.6 0.1 0.057 13.6 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif RRM_5 PF13893.6 ETS80681.1 - 0.03 13.9 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-H2C2_2 PF13465.6 ETS80682.1 - 1.2e-09 38.1 8.5 1e-06 28.9 1.4 5.0 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2 PF00096.26 ETS80682.1 - 2.6e-09 37.0 48.1 0.00016 21.9 0.2 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS80682.1 - 0.0029 18.3 43.4 0.0037 18.0 0.2 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ETS80682.1 - 0.0045 17.2 1.9 0.0045 17.2 1.9 3.0 2 1 1 3 3 3 2 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 ETS80682.1 - 0.0066 16.2 0.1 0.0066 16.2 0.1 4.4 4 0 0 4 4 4 1 C2H2-type zinc-finger domain CDC45 PF02724.14 ETS80682.1 - 0.067 11.5 8.9 0.11 10.8 8.9 1.3 1 0 0 1 1 1 0 CDC45-like protein TBPIP PF07106.13 ETS80682.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.7 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain DUF2052 PF09747.9 ETS80682.1 - 0.49 10.5 13.9 0.094 12.8 10.2 1.6 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Urm1 PF09138.11 ETS80683.1 - 2.2e-08 34.3 0.0 2.8e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) Grg1 PF11034.8 ETS80686.1 - 2.8e-31 107.5 11.4 3.2e-31 107.4 11.4 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 DUF3570 PF12094.8 ETS80686.1 - 0.047 12.5 0.8 0.047 12.5 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) Ribosomal_L38e PF01781.18 ETS80687.1 - 8e-34 115.6 2.5 9.5e-34 115.3 2.5 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DNA_pol_B PF00136.21 ETS80688.1 - 6.7e-148 493.2 2.4 9.7e-148 492.7 2.4 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 ETS80688.1 - 3.8e-78 263.0 0.2 8.2e-78 261.9 0.2 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 ETS80688.1 - 1.1e-17 64.2 5.5 2.7e-17 63.0 5.5 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 ETS80688.1 - 0.00093 18.2 0.7 0.067 12.0 0.0 2.4 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 ETS80688.1 - 0.0037 17.3 0.4 0.031 14.3 0.4 2.5 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 ETS80688.1 - 0.018 14.7 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.22 ETS80688.1 - 0.14 12.1 9.3 0.06 13.2 0.7 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ELFV_dehydrog PF00208.21 ETS80689.1 - 2.8e-85 285.9 2.4 3.5e-85 285.6 2.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 ETS80689.1 - 1.3e-50 170.6 0.0 2.3e-50 169.8 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 ETS80689.1 - 0.015 15.7 0.0 0.033 14.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Qn_am_d_aIV PF09100.10 ETS80689.1 - 0.13 12.1 0.3 0.28 11.0 0.3 1.6 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV GMC_oxred_C PF05199.13 ETS80690.1 - 1e-08 35.8 0.4 3.7e-07 30.8 0.0 3.4 4 0 0 4 4 4 1 GMC oxidoreductase GMC_oxred_N PF00732.19 ETS80690.1 - 1.8e-07 30.8 0.1 1.4e-06 27.9 0.1 2.4 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS80690.1 - 0.00031 19.9 0.3 0.00057 19.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Hydrolase_4 PF12146.8 ETS80690.1 - 0.00067 19.0 0.0 0.089 12.0 0.0 2.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 FAD_oxidored PF12831.7 ETS80690.1 - 0.00086 18.8 0.1 0.0014 18.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS80690.1 - 0.0046 16.2 0.2 0.012 14.8 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS80690.1 - 0.013 15.7 0.6 0.046 13.9 0.6 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ETS80690.1 - 0.024 13.7 0.1 0.041 13.0 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A PSY3 PF16836.5 ETS80690.1 - 0.094 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description TLP1_add_C PF18313.1 ETS80692.1 - 3.9e-20 71.6 0.0 7.3e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain p450 PF00067.22 ETS80694.1 - 1.7e-30 106.2 0.0 2.8e-14 52.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.16 ETS80696.1 - 1.2e-25 90.2 25.3 1.2e-25 90.2 25.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 ETS80697.1 - 7.4e-23 81.0 0.0 1e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS80697.1 - 2.8e-11 43.5 0.0 3.5e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS80697.1 - 2.2e-05 24.5 0.0 4.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ETS80697.1 - 4.5e-05 23.4 0.0 8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS80697.1 - 0.00029 20.5 0.0 0.00047 19.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DUF3328 PF11807.8 ETS80698.1 - 3.9e-44 151.1 0.2 5.1e-44 150.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) LRR19-TM PF15176.6 ETS80698.1 - 0.0071 16.3 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain Shisa PF13908.6 ETS80698.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator HET PF06985.11 ETS80699.1 - 6.3e-11 42.8 5.1 7.3e-08 32.9 1.8 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) CC2-LZ PF16516.5 ETS80700.1 - 0.084 13.2 0.4 0.18 12.2 0.4 1.5 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Plasmid_RAQPRD PF09686.10 ETS80700.1 - 0.27 11.5 3.8 0.74 10.1 3.8 1.7 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) ADH_zinc_N_2 PF13602.6 ETS80701.1 - 8e-29 101.4 0.0 1.2e-28 100.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ETS80701.1 - 6.1e-15 55.4 0.1 1e-14 54.6 0.1 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS80701.1 - 0.00017 21.5 0.0 0.031 14.1 0.0 2.4 2 0 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain SQHop_cyclase_C PF13243.6 ETS80703.1 - 4.4e-83 279.0 0.6 9.2e-43 146.5 0.0 2.8 1 1 1 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 ETS80703.1 - 3e-41 141.4 0.0 1.1e-37 129.7 0.0 3.1 3 0 0 3 3 3 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 ETS80703.1 - 1.9e-07 30.7 14.4 9.7e-05 22.0 0.6 4.0 4 1 0 4 4 4 2 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 ETS80704.1 - 5.2e-38 130.8 0.0 6.3e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 ETS80704.1 - 3.1e-06 26.8 0.0 1.5e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 ETS80704.1 - 0.0034 16.5 0.0 0.0089 15.2 0.1 1.6 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain p450 PF00067.22 ETS80705.1 - 1.2e-70 238.5 0.0 1.6e-70 238.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1003 PF06210.11 ETS80705.1 - 1.5 9.0 3.8 2.9 8.0 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) F-box PF00646.33 ETS80707.1 - 3.7e-06 26.7 0.1 9.7e-06 25.3 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ETS80707.1 - 0.0033 17.3 0.2 0.011 15.7 0.1 1.9 2 0 0 2 2 2 1 F-box-like PAN_4 PF14295.6 ETS80708.1 - 1.5e-08 34.4 1.3 0.048 13.6 0.1 3.6 3 0 0 3 3 3 3 PAN domain MANEC PF07502.14 ETS80708.1 - 2.6e-05 24.4 1.6 2.3 8.5 0.0 3.5 3 1 0 3 3 3 3 MANEC domain Trypan_glycop PF00913.19 ETS80708.1 - 0.1 11.9 10.1 0.18 11.0 10.1 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) PAN_2 PF08276.11 ETS80708.1 - 0.35 11.0 6.7 4.3 7.5 0.1 3.1 3 0 0 3 3 3 0 PAN-like domain T5orf172 PF10544.9 ETS80709.1 - 5.1e-12 46.2 2.6 7.7e-11 42.5 2.6 2.6 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 ETS80709.1 - 1.2e-08 35.5 0.2 3.2e-08 34.1 0.2 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 HET PF06985.11 ETS80710.1 - 0.0021 18.4 3.7 0.16 12.3 0.0 3.4 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) DUF1764 PF08576.10 ETS80710.1 - 2.5 9.0 4.7 5.6 7.9 4.7 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF3987 PF13148.6 ETS80710.1 - 4.7 6.1 6.0 7.7 5.4 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Rhodanese PF00581.20 ETS80711.1 - 7.5e-06 26.4 0.0 9.3e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain FMN_red PF03358.15 ETS80712.1 - 3.8e-25 88.4 0.0 4.9e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ETS80712.1 - 0.04 13.6 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin-like fold Abhydrolase_6 PF12697.7 ETS80713.1 - 6.9e-15 56.2 0.0 7.9e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS80713.1 - 0.00036 19.9 0.0 0.00074 18.8 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 ETS80713.1 - 0.0054 16.5 0.1 0.011 15.5 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family CN_hydrolase PF00795.22 ETS80714.1 - 6.9e-27 94.4 0.1 8.8e-27 94.1 0.1 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Amidase PF01425.21 ETS80715.1 - 4.3e-29 101.8 0.2 4.3e-29 101.8 0.2 1.9 2 0 0 2 2 2 1 Amidase SopA_C PF13979.6 ETS80715.1 - 0.086 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 SopA-like catalytic domain DUF4880 PF16220.5 ETS80715.1 - 0.13 12.2 0.1 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) Fungal_trans PF04082.18 ETS80716.1 - 4.9e-24 84.8 0.0 8.4e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS80716.1 - 1.1e-07 31.8 6.2 2.5e-07 30.7 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1192 PF06698.11 ETS80716.1 - 0.17 12.0 0.1 0.36 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) FAD_binding_3 PF01494.19 ETS80717.1 - 1.5e-29 103.4 0.0 2.5e-28 99.3 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS80717.1 - 1.8e-06 27.4 0.2 0.0005 19.4 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS80717.1 - 3.9e-05 22.9 0.3 0.00044 19.4 0.3 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ETS80717.1 - 0.00011 22.3 0.2 0.00022 21.4 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 ETS80717.1 - 0.00024 20.3 0.0 0.037 13.1 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_3 PF13738.6 ETS80717.1 - 0.0012 18.2 0.0 0.016 14.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ETS80717.1 - 0.0013 17.7 1.0 0.48 9.2 0.2 3.1 3 1 1 4 4 4 2 Tryptophan halogenase HI0933_like PF03486.14 ETS80717.1 - 0.0016 17.2 0.0 0.0087 14.8 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 ETS80717.1 - 0.004 16.8 2.1 0.18 11.4 1.4 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS80717.1 - 0.0066 15.6 0.6 0.02 14.0 0.4 1.9 2 1 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 ETS80717.1 - 0.03 13.6 0.0 0.59 9.4 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase MACPF PF01823.19 ETS80719.1 - 4.7e-05 23.6 2.8 4.7e-05 23.6 2.8 3.9 5 1 0 5 5 5 1 MAC/Perforin domain TP53IP5 PF15331.6 ETS80719.1 - 4.5 7.4 12.8 3.8 7.6 3.9 2.9 3 0 0 3 3 3 0 Cellular tumour antigen p53-inducible 5 FMO-like PF00743.19 ETS80720.1 - 5.8e-14 51.4 0.6 2.6e-13 49.2 0.2 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ETS80720.1 - 1.6e-08 34.1 0.0 1.2e-06 27.9 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ETS80720.1 - 6.1e-08 32.3 0.0 3.1e-07 30.0 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS80720.1 - 6.5e-07 29.5 0.0 1.4e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS80720.1 - 7.1e-05 22.2 0.0 0.017 14.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS80720.1 - 0.0046 17.0 0.1 0.11 12.5 0.0 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding Ank_4 PF13637.6 ETS80721.1 - 1.8e-11 44.3 0.3 0.72 10.5 0.0 6.8 6 1 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS80721.1 - 3.1e-10 39.4 1.1 0.2 12.3 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat Ank_2 PF12796.7 ETS80721.1 - 4.1e-10 40.1 0.1 0.006 17.1 0.0 3.9 3 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 ETS80721.1 - 3.4e-08 33.6 5.1 1.3 9.6 0.0 6.0 5 2 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 ETS80721.1 - 4.7e-07 30.0 0.7 0.45 10.9 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeats (many copies) P-mevalo_kinase PF04275.14 ETS80722.1 - 1.2e-21 76.7 0.0 2.4e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Phosphomevalonate kinase Pribosyltran PF00156.27 ETS80722.1 - 8.6e-17 61.1 0.0 1.7e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.23 ETS80722.1 - 5.2e-14 52.2 1.4 1.2e-13 51.0 1.4 1.7 1 0 0 1 1 1 1 FAD binding domain Methyltransf_23 PF13489.6 ETS80722.1 - 0.0016 18.3 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPRTase PF14681.6 ETS80722.1 - 0.0047 16.4 0.0 0.0092 15.4 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase BBE PF08031.12 ETS80722.1 - 0.024 14.7 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like PRTase_2 PF15609.6 ETS80722.1 - 0.06 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase GTP_cyclohydroI PF01227.22 ETS80723.1 - 4.5e-15 55.5 0.0 5.9e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I GLEYA PF10528.9 ETS80724.1 - 5e-29 100.6 0.3 5e-29 100.6 0.3 2.6 2 1 1 3 3 3 1 GLEYA domain PA14 PF07691.12 ETS80724.1 - 3.9e-08 33.2 0.1 1.3e-07 31.5 0.1 2.0 1 1 0 1 1 1 1 PA14 domain DUF1897 PF09005.10 ETS80724.1 - 0.00055 19.4 0.5 0.00098 18.6 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1897) adh_short_C2 PF13561.6 ETS80725.1 - 1.8e-50 171.7 8.9 3.1e-50 170.9 8.9 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS80725.1 - 4e-40 137.4 4.4 9e-40 136.2 4.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS80725.1 - 2.3e-10 40.7 3.6 4.1e-09 36.6 0.6 2.8 3 0 0 3 3 3 1 KR domain Polysacc_synt_2 PF02719.15 ETS80725.1 - 0.0095 15.1 0.2 0.016 14.4 0.2 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein PA PF02225.22 ETS80725.1 - 0.041 13.9 2.4 0.11 12.5 2.4 1.8 1 0 0 1 1 1 0 PA domain Epimerase PF01370.21 ETS80725.1 - 0.043 13.3 1.2 0.044 13.2 0.2 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.23 ETS80725.1 - 0.29 11.2 2.7 1.2 9.2 0.3 2.3 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain HHH_5 PF14520.6 ETS80725.1 - 1.7 9.3 4.2 7 7.3 0.1 2.8 3 0 0 3 3 3 0 Helix-hairpin-helix domain DUF3341 PF11821.8 ETS80726.1 - 0.065 12.9 1.1 2.1 7.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) AA_permease_2 PF13520.6 ETS80727.1 - 1.1e-27 96.9 33.6 1.4e-27 96.6 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS80727.1 - 3.6e-13 48.9 29.9 4.7e-13 48.6 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease FAD_binding_4 PF01565.23 ETS80728.1 - 7.8e-23 80.8 1.1 1.5e-22 79.8 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS80728.1 - 3.7e-08 33.3 0.1 9.6e-08 32.0 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 ETS80728.1 - 0.12 11.8 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Methyltransf_25 PF13649.6 ETS80729.1 - 0.0013 19.4 0.0 0.0024 18.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS80729.1 - 0.0045 17.6 0.0 0.0081 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ETS80729.1 - 0.14 11.5 0.1 0.25 10.7 0.0 1.4 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) NAD_binding_10 PF13460.6 ETS80731.1 - 2.7e-22 79.6 0.0 3.5e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS80731.1 - 3.5e-07 30.0 0.0 7.5e-07 28.9 0.0 1.6 1 1 1 2 2 2 1 NmrA-like family Epimerase PF01370.21 ETS80731.1 - 7.9e-05 22.2 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 ETS80731.1 - 0.0064 16.7 0.0 0.0096 16.2 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Fungal_trans_2 PF11951.8 ETS80732.1 - 4.7e-45 154.0 4.6 6.5e-45 153.6 4.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS80732.1 - 4.7e-07 29.8 7.8 1e-06 28.8 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NPP1 PF05630.11 ETS80733.1 - 4.1e-49 167.4 1.8 5.9e-49 166.9 1.8 1.2 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Gly-zipper_OmpA PF13436.6 ETS80733.1 - 0.041 13.7 12.9 0.074 12.9 12.9 1.4 1 0 0 1 1 1 0 Glycine-zipper domain Shadoo PF14999.6 ETS80733.1 - 0.057 13.5 5.5 0.13 12.4 5.5 1.5 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective p450 PF00067.22 ETS80734.1 - 3.3e-68 230.5 0.0 4.2e-68 230.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LRR_6 PF13516.6 ETS80735.1 - 1.9e-11 43.0 0.6 0.028 14.4 0.0 6.6 7 0 0 7 7 7 3 Leucine Rich repeat F-box-like PF12937.7 ETS80735.1 - 2.3e-11 43.4 0.4 6.4e-11 42.0 0.2 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ETS80735.1 - 1.8e-07 30.8 0.1 6.3e-07 29.1 0.1 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 ETS80735.1 - 1.4e-05 25.3 9.5 0.071 13.6 0.2 5.2 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) DUF3726 PF12525.8 ETS80735.1 - 0.11 12.6 0.0 1.6 8.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3726) LRR_1 PF00560.33 ETS80735.1 - 0.83 10.4 15.7 1.4 9.8 0.6 6.3 6 2 0 6 6 6 0 Leucine Rich Repeat Efg1 PF10153.9 ETS80737.1 - 5.3e-32 110.6 13.9 1.4e-31 109.2 13.9 1.8 1 0 0 1 1 1 1 rRNA-processing protein Efg1 DUF3091 PF11291.8 ETS80737.1 - 0.034 14.3 1.5 0.093 12.9 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3091) CCDC-167 PF15188.6 ETS80737.1 - 0.036 14.4 2.6 0.036 14.4 2.6 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF3490 PF11995.8 ETS80737.1 - 0.27 11.0 7.7 0.23 11.3 4.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3490) NuA4 PF09340.10 ETS80737.1 - 3.8 7.5 6.5 6.6 6.7 0.3 3.0 1 1 1 2 2 2 0 Histone acetyltransferase subunit NuA4 zinc_ribbon_16 PF17034.5 ETS80738.1 - 2.3e-16 60.1 5.3 5e-16 59.0 5.3 1.6 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 ETS80738.1 - 1.8e-05 24.2 3.9 1.8e-05 24.2 3.9 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type HCV_NS5a PF01506.19 ETS80738.1 - 1.1 9.2 5.9 2.7 7.9 5.9 1.7 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a protein membrane anchor CsbD PF05532.12 ETS80739.1 - 6.4e-08 32.4 7.7 0.00078 19.3 0.7 2.3 1 1 1 2 2 2 2 CsbD-like MAPEG PF01124.18 ETS80740.1 - 1.2e-20 73.7 0.2 1.4e-20 73.5 0.2 1.0 1 0 0 1 1 1 1 MAPEG family BCNT PF07572.12 ETS80741.1 - 1.9e-24 85.5 2.7 3.5e-24 84.7 2.7 1.4 1 0 0 1 1 1 1 Bucentaur or craniofacial development DUF4679 PF15728.5 ETS80741.1 - 0.65 9.0 3.2 1.2 8.1 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) Peptidase_C2 PF00648.21 ETS80742.1 - 1.7e-63 214.4 1.7 2e-62 210.9 1.7 2.2 1 1 0 1 1 1 1 Calpain family cysteine protease Spatacsin_C PF14649.6 ETS80742.1 - 0.35 9.9 1.5 0.6 9.2 1.5 1.3 1 0 0 1 1 1 0 Spatacsin C-terminus EF-hand_4 PF12763.7 ETS80743.1 - 0.00082 19.3 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 ETS80743.1 - 0.19 12.2 0.0 0.37 11.3 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair MAP65_ASE1 PF03999.12 ETS80744.1 - 8.7e-80 269.1 6.6 3.2e-79 267.2 6.9 1.6 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) SKA2 PF16740.5 ETS80744.1 - 0.0015 18.3 4.1 0.0041 16.9 0.5 3.3 4 0 0 4 4 4 1 Spindle and kinetochore-associated protein 2 Spectrin PF00435.21 ETS80744.1 - 0.033 14.7 0.4 0.033 14.7 0.4 3.8 5 0 0 5 5 5 0 Spectrin repeat BAR_3 PF16746.5 ETS80744.1 - 0.15 11.8 4.2 1.5 8.5 0.7 2.5 2 0 0 2 2 2 0 BAR domain of APPL family BLOC1_2 PF10046.9 ETS80744.1 - 0.92 9.9 3.6 40 4.6 2.5 3.6 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Dus PF01207.17 ETS80745.1 - 4.6e-56 190.2 0.0 1.7e-55 188.4 0.0 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) BKACE PF05853.12 ETS80745.1 - 0.021 14.1 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme Zn_clus PF00172.18 ETS80747.1 - 9.8e-09 35.2 8.2 1.6e-08 34.5 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 ETS80748.1 - 1.8e-130 435.8 31.1 2.1e-130 435.6 31.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS80748.1 - 3.2e-27 95.4 48.4 5.3e-20 71.7 26.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS80748.1 - 7.5e-09 34.9 12.2 6.1e-07 28.6 3.7 2.2 1 1 1 2 2 2 2 MFS_1 like family Herpes_LMP1 PF05297.11 ETS80748.1 - 2.4 7.3 8.1 4.9 6.3 8.1 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) SAVED PF18145.1 ETS80750.1 - 0.15 11.8 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain DEAD PF00270.29 ETS80752.1 - 0.0085 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase TPALS PF18178.1 ETS80752.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family Phage_int_SAM_6 PF18644.1 ETS80753.1 - 0.2 11.7 0.0 2.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Phage integrase SAM-like domain Amido_AtzD_TrzD PF09663.10 ETS80755.1 - 3.2e-89 299.5 3.6 1.7e-88 297.1 3.6 1.8 1 1 0 1 1 1 1 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) HET PF06985.11 ETS80756.1 - 8.8e-20 71.5 0.0 1.6e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.24 ETS80757.1 - 7.9e-103 344.7 31.1 9e-103 344.5 31.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS80757.1 - 1.2e-32 113.3 28.9 1.2e-32 113.3 28.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 ETS80757.1 - 0.59 10.7 14.0 1.4 9.5 2.7 4.0 4 0 0 4 4 4 0 Phage holin family 2 Fungal_trans_2 PF11951.8 ETS80758.1 - 9.8e-08 31.2 0.1 5.2e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain ADH_N PF08240.12 ETS80759.1 - 1.7e-28 98.6 0.1 3.8e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS80759.1 - 3e-08 33.7 0.1 6.3e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 ETS80759.1 - 1.3e-06 28.2 0.0 3.1e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 ETS80759.1 - 2.2e-05 24.1 0.0 0.00048 19.7 0.0 2.1 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 ETS80759.1 - 0.0013 17.5 0.2 0.0056 15.4 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 ETS80759.1 - 0.0019 17.5 0.2 0.0033 16.8 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 ETS80759.1 - 0.048 14.2 0.2 0.31 11.6 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS80759.1 - 0.053 12.8 0.0 0.07 12.4 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 ETS80759.1 - 0.073 12.6 0.2 0.18 11.3 0.2 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS80759.1 - 0.077 12.1 0.2 0.13 11.3 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 ETS80759.1 - 0.092 13.0 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_25 PF13649.6 ETS80759.1 - 0.11 13.2 0.0 0.26 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 ETS80759.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AP_endonuc_2 PF01261.24 ETS80760.1 - 3e-11 43.2 0.0 4.9e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Img2 PF05046.14 ETS80761.1 - 9.3e-15 54.7 0.1 1.2e-14 54.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.10 ETS80762.1 - 1.8e-49 167.6 0.7 2.4e-48 163.9 2.8 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 ETS80762.1 - 2.8e-12 47.1 0.2 7e-12 45.8 0.2 1.7 1 0 0 1 1 1 1 PCI domain Response_reg PF00072.24 ETS80763.1 - 3.5e-12 46.5 0.0 5.7e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain SnoaL_4 PF13577.6 ETS80764.1 - 0.0064 16.6 0.0 0.011 15.9 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain Methyltr_RsmB-F PF01189.17 ETS80764.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F ECH_1 PF00378.20 ETS80765.1 - 3.7e-25 88.7 0.0 4.9e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ETS80765.1 - 2.8e-14 53.4 0.0 3.2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Vps51 PF08700.11 ETS80766.1 - 2.1e-14 53.4 0.7 1.1e-13 51.1 0.0 2.5 2 0 0 2 2 2 1 Vps51/Vps67 F-box PF00646.33 ETS80767.1 - 2.8e-06 27.1 0.0 1e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ETS80767.1 - 0.00089 19.1 0.4 0.0057 16.5 0.0 2.6 2 1 1 3 3 3 1 F-box-like LRR_4 PF12799.7 ETS80767.1 - 0.0023 18.3 1.8 27 5.4 0.2 4.1 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) DUF3152 PF11350.8 ETS80767.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) DUF1349 PF07081.11 ETS80768.1 - 2.6e-21 76.2 0.1 3.7e-21 75.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Aldo_ket_red PF00248.21 ETS80769.1 - 4.1e-36 124.7 0.0 1.1e-23 83.9 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Dev_Cell_Death PF10539.9 ETS80769.1 - 0.043 13.7 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Development and cell death domain PQ-loop PF04193.14 ETS80770.1 - 2.2e-39 133.0 10.4 1e-19 70.0 1.2 2.6 2 0 0 2 2 2 2 PQ loop repeat HTH_Bact PF18768.1 ETS80770.1 - 0.0094 15.5 0.2 0.021 14.4 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix bacterial domain MtN3_slv PF03083.16 ETS80770.1 - 0.053 13.6 0.2 0.21 11.7 0.2 2.0 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange DUF5102 PF17104.5 ETS80771.1 - 0.2 11.6 16.6 0.075 13.1 0.8 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5102) KH_1 PF00013.29 ETS80772.1 - 2.3e-40 136.3 11.0 1.5e-15 56.8 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ETS80772.1 - 3.9e-10 39.4 9.5 0.011 15.6 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ETS80772.1 - 1.9e-07 30.9 5.5 0.022 14.6 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 ETS80772.1 - 6.7e-05 22.9 5.4 0.37 10.9 0.1 3.4 3 0 0 3 3 3 3 NusA-like KH domain UAA PF08449.11 ETS80773.1 - 4.7e-43 147.5 7.2 6.7e-43 147.0 7.2 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 ETS80773.1 - 3.6e-07 30.4 27.3 0.00016 21.8 10.6 3.4 3 1 0 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.15 ETS80773.1 - 0.001 18.3 1.5 0.083 12.0 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter CRT-like PF08627.10 ETS80773.1 - 0.0053 15.8 5.6 0.29 10.0 0.1 2.2 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 ETS80773.1 - 0.044 13.1 10.8 0.39 10.0 2.1 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family DSPc PF00782.20 ETS80774.1 - 1.1e-23 83.5 0.1 2.6e-22 79.1 0.1 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ETS80774.1 - 0.00087 18.9 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 ETS80774.1 - 0.037 14.3 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain Pkinase PF00069.25 ETS80775.1 - 7.5e-13 48.4 0.0 1.9e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS80775.1 - 0.053 12.8 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase zf-C2H2_4 PF13894.6 ETS80775.1 - 0.3 12.0 19.7 1.3 10.0 0.4 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger ZapA PF05164.13 ETS80775.1 - 0.37 11.3 1.7 1 9.8 1.7 1.7 1 0 0 1 1 1 0 Cell division protein ZapA HET PF06985.11 ETS80777.1 - 5.4e-31 107.9 0.3 7.8e-31 107.4 0.3 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) polyprenyl_synt PF00348.17 ETS80778.1 - 6e-86 287.7 0.1 7.7e-86 287.3 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Homeodomain PF00046.29 ETS80778.1 - 0.091 12.6 0.0 0.28 11.0 0.0 1.9 1 0 0 1 1 1 0 Homeodomain ANAPC8 PF04049.13 ETS80779.1 - 3.5e-54 182.6 0.5 7.1e-54 181.7 0.1 1.7 2 0 0 2 2 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 ETS80779.1 - 1.4e-19 69.0 3.2 0.00065 19.4 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 ETS80779.1 - 1.6e-18 65.3 12.0 6.9e-05 22.8 0.0 6.9 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 ETS80779.1 - 1.7e-10 40.2 21.9 0.32 11.2 0.0 8.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 ETS80779.1 - 9.8e-10 38.9 6.3 5.8e-06 26.9 0.7 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 ETS80779.1 - 1.4e-09 37.9 13.1 0.0057 17.4 0.1 7.5 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 ETS80779.1 - 6.8e-08 32.1 0.2 2.4e-06 27.1 0.1 3.0 1 1 1 2 2 2 1 TPR repeat TPR_12 PF13424.6 ETS80779.1 - 1.8e-06 28.2 18.5 1.2 9.5 0.0 7.4 7 1 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 ETS80779.1 - 1.1e-05 25.1 4.5 0.42 10.8 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS80779.1 - 3e-05 24.2 10.6 0.97 9.7 0.2 6.3 5 1 2 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 ETS80779.1 - 0.00062 20.2 13.2 8.3 7.0 0.0 7.1 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 ETS80779.1 - 0.0057 16.8 9.6 1.9 8.7 0.2 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat Sel1 PF08238.12 ETS80779.1 - 0.0098 16.6 9.5 2.8 8.8 0.1 5.0 5 0 0 5 5 4 1 Sel1 repeat DUF3856 PF12968.7 ETS80779.1 - 0.017 15.2 1.0 0.34 11.0 0.1 2.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 ETS80779.1 - 0.074 12.9 2.9 12 5.9 0.4 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat REV1_C PF16727.5 ETS80779.1 - 0.082 13.3 0.4 22 5.5 0.0 2.7 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain ChAPs PF09295.10 ETS80779.1 - 0.091 11.8 0.0 2.8 6.9 0.0 2.4 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Say1_Mug180 PF10340.9 ETS80779.1 - 0.16 10.8 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase TPR_6 PF13174.6 ETS80779.1 - 0.27 12.0 16.5 26 5.7 0.6 7.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 ETS80779.1 - 0.52 10.8 3.9 9.4 6.9 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Tweety PF04906.13 ETS80780.1 - 0.02 13.6 0.4 0.026 13.2 0.4 1.1 1 0 0 1 1 1 0 Tweety Synthase_beta PF11421.8 ETS80780.1 - 4.2 8.1 7.8 1.3 9.8 1.1 2.7 3 0 0 3 3 3 0 ATP synthase F1 beta subunit Ank_2 PF12796.7 ETS80782.1 - 4.2e-28 97.8 0.0 2.1e-05 25.0 0.0 6.2 5 1 2 7 7 7 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS80782.1 - 3.3e-21 75.0 2.6 0.00033 20.9 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS80782.1 - 3.1e-18 65.9 12.0 2.6e-05 24.7 0.4 7.4 5 3 2 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 ETS80782.1 - 9.7e-18 63.8 8.6 0.038 14.4 0.2 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 ETS80782.1 - 9.5e-16 56.3 10.3 0.0013 19.1 0.1 8.6 10 0 0 10 10 10 4 Ankyrin repeat F-box PF00646.33 ETS80782.1 - 0.0019 18.0 1.2 0.013 15.3 0.2 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ETS80782.1 - 0.031 14.2 0.1 0.086 12.7 0.1 1.8 1 0 0 1 1 1 0 F-box-like DUF4142 PF13628.6 ETS80782.1 - 0.048 13.9 0.0 0.081 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) Septin PF00735.18 ETS80783.1 - 3.2e-111 371.1 0.4 4.5e-111 370.6 0.4 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ETS80783.1 - 8.9e-07 29.0 0.0 1.9e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ETS80783.1 - 1.9e-05 24.3 3.9 0.00038 20.1 0.1 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ETS80783.1 - 6.9e-05 22.8 1.6 0.00039 20.4 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 ETS80783.1 - 0.0067 16.7 0.8 0.021 15.1 0.1 2.2 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 ETS80783.1 - 0.013 15.8 0.1 0.03 14.5 0.1 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FOXP-CC PF16159.5 ETS80783.1 - 0.024 15.3 1.3 0.024 15.3 1.3 2.5 2 1 1 3 3 3 0 FOXP coiled-coil domain Ras PF00071.22 ETS80783.1 - 0.04 13.5 0.4 0.13 11.9 0.4 1.8 1 1 0 1 1 1 0 Ras family Val_tRNA-synt_C PF10458.9 ETS80783.1 - 0.059 13.7 0.8 0.059 13.7 0.8 2.6 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Pox_A32 PF04665.12 ETS80783.1 - 0.09 12.2 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein Casc1_N PF15927.5 ETS80783.1 - 0.12 12.0 11.5 0.32 10.6 11.5 1.7 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus AAA_16 PF13191.6 ETS80783.1 - 0.3 11.4 2.3 0.58 10.5 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 ETS80783.1 - 1.3 9.1 7.0 3.2 7.8 0.1 3.1 2 1 1 3 3 3 0 Dynamin family FUSC PF04632.12 ETS80783.1 - 1.9 6.9 4.4 2.9 6.3 4.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6_N PF17675.1 ETS80783.1 - 2.7 8.5 14.7 0.62 10.6 9.9 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region BCDHK_Adom3 PF10436.9 ETS80784.1 - 2.5e-47 160.7 0.1 4.6e-47 159.9 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ETS80784.1 - 1.5e-07 31.9 0.0 4.9e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ETS80784.1 - 0.12 12.3 0.0 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain USP7_ICP0_bdg PF12436.8 ETS80785.1 - 7.1e-85 284.1 0.0 3.6e-83 278.6 0.0 2.7 2 1 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 ETS80785.1 - 1.3e-70 237.3 1.5 6.9e-67 225.1 0.5 3.7 4 0 0 4 4 4 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 ETS80785.1 - 4e-46 157.6 0.4 7.9e-46 156.6 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ETS80785.1 - 1.7e-22 80.4 0.0 5.4e-22 78.8 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 ETS80785.1 - 6.3e-10 39.2 0.0 1.9e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 MATH domain DEK_C PF08766.11 ETS80785.1 - 0.027 14.4 0.2 0.17 11.8 0.0 2.5 2 0 0 2 2 2 0 DEK C terminal domain Tim17 PF02466.19 ETS80786.1 - 7.8e-39 132.5 11.5 1.1e-38 132.0 11.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SKIP_SNW PF02731.15 ETS80788.1 - 1.6e-70 235.9 5.5 1.6e-70 235.9 5.5 2.4 2 0 0 2 2 2 1 SKIP/SNW domain EMP24_GP25L PF01105.24 ETS80789.1 - 2.1e-45 154.9 1.1 2.4e-45 154.7 1.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Glyco_hydro_63N PF16923.5 ETS80789.1 - 0.11 12.6 0.5 0.43 10.6 0.5 1.8 1 1 0 1 1 1 0 Glycosyl hydrolase family 63 N-terminal domain PhoD PF09423.10 ETS80790.1 - 2.7e-42 145.1 0.2 7.1e-42 143.7 0.2 1.6 1 1 0 1 1 1 1 PhoD-like phosphatase PMP1_2 PF08114.11 ETS80790.1 - 0.033 13.9 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase proteolipid family FixO PF02433.15 ETS80791.1 - 0.056 12.9 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO MLANA PF14991.6 ETS80791.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A TMEM154 PF15102.6 ETS80792.1 - 0.00017 21.5 1.0 0.00031 20.7 1.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Podoplanin PF05808.11 ETS80792.1 - 0.0005 20.2 0.3 0.00075 19.6 0.3 1.3 1 0 0 1 1 1 1 Podoplanin DUF1180 PF06679.12 ETS80792.1 - 0.0036 17.8 0.2 0.0065 16.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) EphA2_TM PF14575.6 ETS80792.1 - 0.004 18.0 0.1 0.013 16.4 0.0 1.9 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Pex14_N PF04695.13 ETS80792.1 - 0.04 14.6 0.6 0.41 11.3 0.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region STE2 PF02116.15 ETS80792.1 - 0.066 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR RIFIN PF02009.16 ETS80792.1 - 0.11 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Rifin HET PF06985.11 ETS80793.1 - 8.2e-26 91.1 0.0 1.5e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TauD PF02668.16 ETS80794.1 - 4e-31 108.8 0.0 5.3e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 ETS80794.1 - 0.00068 20.2 0.1 0.0018 18.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 ETS80794.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.4 2 0 0 2 2 2 0 CsiD Metallophos PF00149.28 ETS80795.1 - 3.4e-38 132.2 0.1 5.9e-38 131.4 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cyclase PF04199.13 ETS80796.1 - 1e-12 48.5 0.0 1.6e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase HD_3 PF13023.6 ETS80796.1 - 0.024 14.5 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 HD domain DIOX_N PF14226.6 ETS80797.1 - 7.1e-24 84.8 0.0 1.2e-23 84.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS80797.1 - 1.3e-21 77.0 0.0 2.4e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PAC3 PF10178.9 ETS80798.1 - 0.00027 21.0 0.0 0.0004 20.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 HA2 PF04408.23 ETS80799.1 - 7.7e-24 84.1 0.0 7.7e-24 84.1 0.0 3.0 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ETS80799.1 - 1.9e-11 44.3 0.0 3.1e-10 40.4 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 ETS80799.1 - 1.1e-10 41.7 0.0 2.9e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 ETS80799.1 - 1.8e-08 34.4 0.1 6.2e-08 32.6 0.1 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ETS80799.1 - 0.00039 20.7 0.6 0.0014 18.9 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 ETS80799.1 - 0.00067 20.2 0.0 0.00067 20.2 0.0 4.0 4 1 0 4 4 4 1 AAA domain AAA_19 PF13245.6 ETS80799.1 - 0.0045 17.3 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ETS80799.1 - 0.0072 16.1 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 ETS80799.1 - 0.0099 15.0 0.0 0.026 13.6 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 ETS80799.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family PhoH PF02562.16 ETS80799.1 - 0.027 13.9 0.0 0.068 12.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 ETS80799.1 - 0.043 13.2 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF2075 PF09848.9 ETS80799.1 - 0.062 12.5 0.0 0.062 12.5 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 ETS80799.1 - 0.11 12.7 0.3 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 ETS80799.1 - 0.18 11.8 3.4 12 5.9 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Med6 PF04934.14 ETS80800.1 - 5.3e-38 129.8 0.1 7.4e-38 129.4 0.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component MMtag PF10159.9 ETS80801.1 - 9e-32 109.2 1.4 9e-32 109.2 1.4 2.3 2 0 0 2 2 2 1 Multiple myeloma tumor-associated IHO1 PF15771.5 ETS80801.1 - 0.0028 16.5 0.8 0.003 16.4 0.8 1.1 1 0 0 1 1 1 1 Interactor of HORMAD1 protein 1 Strabismus PF06638.11 ETS80801.1 - 8.7 4.9 6.1 0.45 9.1 1.0 1.4 2 0 0 2 2 2 0 Strabismus protein DUF3684 PF12449.8 ETS80802.1 - 0 1436.9 0.0 0 1436.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 ETS80802.1 - 7.7e-05 22.5 0.0 0.00023 21.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CAS_C PF12026.8 ETS80802.1 - 0.9 9.6 3.3 0.74 9.9 0.1 2.6 2 0 0 2 2 2 0 Crk-Associated Substrate C-terminal domain DUF45 PF01863.17 ETS80802.1 - 1.9 8.5 5.3 0.37 10.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF45 FAD_binding_3 PF01494.19 ETS80803.1 - 1.7e-17 63.7 0.3 3.1e-16 59.6 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain FARP PF01581.16 ETS80804.1 - 0.066 13.7 0.6 59 4.9 0.1 3.4 3 0 0 3 3 3 0 FMRFamide related peptide family Gloverin PF10793.9 ETS80804.1 - 0.36 10.7 12.1 0.86 9.5 2.9 2.9 1 1 2 3 3 3 0 Gloverin-like protein MnmE_helical PF12631.7 ETS80805.1 - 1.5e-38 133.1 0.0 3.6e-38 131.8 0.0 1.6 1 1 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 ETS80805.1 - 3.8e-21 75.5 0.0 1.1e-20 74.1 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 ETS80805.1 - 4.5e-20 71.8 0.0 1.1e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ETS80805.1 - 6.7e-07 29.0 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ETS80805.1 - 5.3e-06 26.4 0.1 0.0033 17.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 ETS80805.1 - 0.00011 22.3 0.0 0.0015 18.6 0.0 2.1 1 1 1 2 2 2 1 Dynamin family AAA_24 PF13479.6 ETS80805.1 - 0.0036 17.0 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 ETS80805.1 - 0.02 15.4 0.7 0.11 13.0 0.1 2.5 1 1 1 2 2 2 0 ABC transporter AIG1 PF04548.16 ETS80805.1 - 0.048 13.0 0.1 0.13 11.6 0.1 1.8 1 1 0 1 1 1 0 AIG1 family Roc PF08477.13 ETS80805.1 - 0.054 13.7 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activ_2 PF14532.6 ETS80805.1 - 0.11 12.6 0.1 0.48 10.5 0.1 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_35 PF14516.6 ETS80805.1 - 0.13 11.1 0.0 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Ribosomal_L28e PF01778.17 ETS80806.1 - 1.4e-38 132.2 2.4 2.7e-38 131.2 2.4 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 ETS80806.1 - 8.8e-30 103.3 17.6 8.8e-30 103.3 17.6 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 ETS80806.1 - 3.3e-06 26.7 19.9 4.2e-06 26.4 19.9 1.1 1 0 0 1 1 1 1 BUD22 TFIIF_alpha PF05793.12 ETS80806.1 - 0.0082 14.8 27.2 0.01 14.5 27.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PYC_OADA PF02436.18 ETS80806.1 - 0.046 13.5 0.9 0.076 12.8 0.9 1.5 1 0 0 1 1 1 0 Conserved carboxylase domain YL1 PF05764.13 ETS80806.1 - 2.8 8.0 38.1 0.31 11.1 28.1 2.2 2 0 0 2 2 2 0 YL1 nuclear protein Mso1_Sec1_bdg PF14475.6 ETS80807.1 - 3.8e-19 68.0 0.0 6.4e-19 67.3 0.0 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 RabGAP-TBC PF00566.18 ETS80808.1 - 2.4e-36 125.4 3.7 5.7e-36 124.2 3.7 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 ETS80808.1 - 8.8e-07 28.5 0.0 0.012 15.1 0.0 3.3 3 0 0 3 3 3 2 Rab-binding domain (RBD) Glyco_hydro_63 PF03200.16 ETS80809.1 - 4.9e-164 546.7 1.9 4.9e-164 546.7 1.9 2.3 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 ETS80809.1 - 4.9e-85 285.2 0.1 4.9e-85 285.2 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 ETS80809.1 - 0.023 13.5 0.1 0.044 12.6 0.1 1.4 1 0 0 1 1 1 0 Trehalase GDE_C PF06202.14 ETS80809.1 - 0.08 11.9 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase SNRNP27 PF08648.12 ETS80810.1 - 8.6e-28 96.2 1.8 1.6e-27 95.3 1.8 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins p450 PF00067.22 ETS80811.1 - 6.7e-66 222.9 0.0 8.5e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_C PF05199.13 ETS80812.1 - 1.1e-29 103.9 0.3 1.8e-29 103.1 0.3 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 ETS80812.1 - 1e-28 100.6 0.0 2.3e-26 92.9 0.0 2.7 1 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 ETS80812.1 - 2.7e-05 23.6 0.0 4.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS80812.1 - 0.001 19.2 0.4 0.0026 18.0 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS80812.1 - 0.015 14.4 0.4 0.041 13.0 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 ETS80812.1 - 0.019 14.2 0.1 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 ETS80812.1 - 0.03 13.4 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ETS80812.1 - 0.037 13.3 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS80812.1 - 0.088 11.5 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 ETS80812.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase AAA PF00004.29 ETS80813.1 - 1.5e-18 67.5 0.0 3.7e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.12 ETS80813.1 - 0.00096 18.8 0.7 0.017 14.7 0.1 2.3 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.6 ETS80813.1 - 0.0015 18.8 0.4 0.019 15.3 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS80813.1 - 0.0024 18.3 2.0 0.14 12.5 1.8 2.6 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 ETS80813.1 - 0.016 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_17 PF13207.6 ETS80813.1 - 0.03 14.8 0.0 0.21 12.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ETS80813.1 - 0.1 13.2 0.0 0.34 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ETS80813.1 - 0.12 12.3 0.1 0.35 10.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF4185 PF13810.6 ETS80813.1 - 0.13 11.5 0.6 0.21 10.8 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) IMUP PF15761.5 ETS80813.1 - 0.33 11.7 3.7 0.26 12.0 1.8 1.8 2 0 0 2 2 1 0 Immortalisation up-regulated protein RCDG1 PF15725.5 ETS80813.1 - 0.65 10.5 3.6 1.9 9.0 3.6 1.7 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein HET PF06985.11 ETS80814.1 - 8e-22 78.2 0.0 2.8e-21 76.4 0.0 2.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.6 ETS80814.1 - 0.0013 19.1 0.0 0.0051 17.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS80814.1 - 0.0046 17.2 0.0 0.024 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ETS80814.1 - 0.0094 15.9 0.1 0.022 14.7 0.1 1.6 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 ETS80814.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CCDC106 PF15794.5 ETS80814.1 - 2.5 7.8 13.5 5.4 6.7 13.5 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Ank_2 PF12796.7 ETS80816.1 - 4.2e-23 81.7 0.0 3e-09 37.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS80816.1 - 2.1e-15 56.6 0.1 1.2e-06 28.7 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS80816.1 - 2.9e-13 50.0 0.4 0.0041 17.7 0.0 4.7 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS80816.1 - 4.6e-13 48.1 0.2 0.09 13.4 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 ETS80816.1 - 1.7e-12 47.2 0.0 0.52 10.9 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.7 ETS80817.1 - 6.5e-35 119.6 4.2 2.7e-13 50.3 0.0 5.2 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS80817.1 - 2.9e-32 110.6 8.0 1.2e-09 38.5 0.0 6.0 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS80817.1 - 3.3e-25 85.4 2.3 0.00011 22.3 0.0 8.2 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 ETS80817.1 - 2.4e-22 78.3 10.5 0.0055 17.1 0.0 7.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 ETS80817.1 - 1.9e-20 72.6 8.9 1.3e-09 38.2 0.2 7.2 1 1 7 8 8 8 5 Ankyrin repeats (many copies) NACHT PF05729.12 ETS80817.1 - 3.9e-16 59.4 0.4 2.2e-15 57.0 0.1 2.2 2 0 0 2 2 2 1 NACHT domain PNP_UDP_1 PF01048.20 ETS80817.1 - 1.9e-06 27.3 0.1 6.2e-06 25.6 0.1 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_14 PF13173.6 ETS80817.1 - 6.1e-05 23.1 0.0 0.0017 18.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS80817.1 - 0.00012 22.5 0.0 0.0005 20.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 ETS80817.1 - 0.00059 20.3 0.0 0.002 18.6 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ETS80817.1 - 0.0008 19.8 0.1 0.016 15.6 0.0 3.0 3 0 0 3 3 3 1 RNA helicase AAA_22 PF13401.6 ETS80817.1 - 0.0011 19.2 0.0 0.0079 16.5 0.0 2.5 2 1 1 3 3 3 1 AAA domain Sec7 PF01369.20 ETS80817.1 - 0.03 14.0 0.0 0.079 12.6 0.0 1.6 2 0 0 2 2 2 0 Sec7 domain NB-ARC PF00931.22 ETS80817.1 - 0.098 11.8 0.0 0.27 10.4 0.0 1.7 1 1 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 ETS80817.1 - 0.14 11.3 0.0 0.37 10.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF5001 PF16392.5 ETS80818.1 - 0.071 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Ig-like domain Chorismate_bind PF00425.18 ETS80819.1 - 7.8e-68 228.8 0.0 2e-67 227.5 0.0 1.7 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 ETS80819.1 - 1.6e-23 83.5 0.0 2e-22 79.9 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 ETS80819.1 - 6e-17 62.2 0.0 2.8e-16 60.0 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 ETS80819.1 - 0.0018 18.0 0.5 0.014 15.2 0.5 2.1 1 1 0 1 1 1 1 Peptidase C26 SMC_N PF02463.19 ETS80820.1 - 4.5e-59 199.6 2.0 8.3e-58 195.4 2.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ETS80820.1 - 1.4e-27 96.3 0.6 1.1e-26 93.4 0.0 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.6 ETS80820.1 - 5.3e-08 32.5 0.1 1.2e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ETS80820.1 - 9.2e-08 32.2 19.3 4.5e-05 23.4 0.1 4.3 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ETS80820.1 - 2.7e-07 31.3 29.7 2.7e-07 31.3 29.7 6.9 2 2 3 5 5 2 2 AAA domain AAA_15 PF13175.6 ETS80820.1 - 8.2e-06 25.8 17.9 8.2e-06 25.8 17.9 5.3 2 2 3 5 5 4 1 AAA ATPase domain Spc7 PF08317.11 ETS80820.1 - 4e-05 22.7 124.7 0.0088 15.0 12.1 7.1 3 2 4 7 7 7 5 Spc7 kinetochore protein Laminin_II PF06009.12 ETS80820.1 - 0.0015 18.6 10.0 0.0015 18.6 10.0 8.2 5 3 3 9 9 9 3 Laminin Domain II ABC_tran_CTD PF16326.5 ETS80820.1 - 0.0029 17.8 8.8 0.0029 17.8 8.8 11.2 8 4 4 12 12 12 2 ABC transporter C-terminal domain SbcCD_C PF13558.6 ETS80820.1 - 0.0057 16.9 0.0 0.049 13.9 0.0 2.7 3 0 0 3 3 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 ETS80820.1 - 0.97 9.9 0.0 0.97 9.9 0.0 7.0 5 3 0 5 5 3 0 ABC transporter DUF948 PF06103.11 ETS80820.1 - 1.3 9.4 34.6 0.97 9.7 1.7 7.1 5 2 1 6 6 6 0 Bacterial protein of unknown function (DUF948) AAA_22 PF13401.6 ETS80820.1 - 1.4 9.2 5.3 24 5.2 0.0 4.5 4 0 0 4 4 4 0 AAA domain DUF1664 PF07889.12 ETS80820.1 - 1.9 8.5 67.2 1 9.4 5.5 8.3 4 3 6 10 10 10 0 Protein of unknown function (DUF1664) Strep_SA_rep PF06696.11 ETS80820.1 - 2.4 8.3 15.1 1.1 9.3 1.5 4.5 3 0 0 3 3 3 0 Streptococcal surface antigen repeat EzrA PF06160.12 ETS80820.1 - 2.9 6.0 88.4 0.0039 15.4 7.3 5.8 4 1 0 5 5 4 0 Septation ring formation regulator, EzrA Nmad4 PF18756.1 ETS80820.1 - 3.4 8.1 6.6 55 4.2 0.0 4.4 4 1 1 5 5 5 0 Nucleotide modification associated domain 4 ATG16 PF08614.11 ETS80820.1 - 4.1 7.6 113.7 0.21 11.8 10.4 7.2 4 1 2 6 6 6 0 Autophagy protein 16 (ATG16) DUF2838 PF10998.8 ETS80821.1 - 3e-45 153.0 11.6 3e-45 153.0 11.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) DUF3584 PF12128.8 ETS80821.1 - 0.25 8.8 4.1 0.34 8.4 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DHR10 PF18595.1 ETS80821.1 - 0.4 10.8 4.8 0.84 9.7 4.8 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Vps5 PF09325.10 ETS80821.1 - 0.64 9.5 4.3 1.2 8.6 4.3 1.4 1 0 0 1 1 1 0 Vps5 C terminal like Atg14 PF10186.9 ETS80821.1 - 0.92 8.5 4.5 1.4 8.0 4.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 WD40 PF00400.32 ETS80822.1 - 4.8e-19 68.3 17.5 0.00024 21.8 0.2 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS80822.1 - 1.9e-13 50.5 5.9 3.5e-05 24.0 0.4 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ETS80822.1 - 6.9e-07 29.3 0.1 0.00093 19.1 0.1 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ETS80822.1 - 0.15 11.0 0.1 1.1 8.1 0.0 2.3 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein NCBP3 PF10309.9 ETS80823.1 - 5.6e-17 61.3 0.1 8.4e-17 60.8 0.1 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Tropomyosin_1 PF12718.7 ETS80824.1 - 0.029 14.5 13.5 1.8 8.7 2.4 2.4 1 1 1 2 2 2 0 Tropomyosin like Tropomyosin PF00261.20 ETS80824.1 - 0.056 12.8 13.1 0.029 13.8 6.7 2.1 1 1 1 2 2 2 0 Tropomyosin XhlA PF10779.9 ETS80824.1 - 0.087 13.0 3.8 0.055 13.7 1.7 1.7 2 0 0 2 2 2 0 Haemolysin XhlA TMCO5 PF14992.6 ETS80824.1 - 0.097 12.2 1.1 0.15 11.6 1.1 1.2 1 0 0 1 1 1 0 TMCO5 family Packaging_FI PF14000.6 ETS80824.1 - 0.24 11.9 3.0 0.15 12.5 0.7 1.8 1 1 1 2 2 2 0 DNA packaging protein FI Vac_Fusion PF02346.16 ETS80824.1 - 2.1 8.0 5.8 4.7 6.9 0.1 3.5 2 1 2 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 SRP_TPR_like PF17004.5 ETS80825.1 - 8e-23 80.7 0.9 2.1e-22 79.3 0.2 2.0 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 ETS80825.1 - 4.9e-16 58.9 6.8 4.9e-16 58.9 6.8 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 ETS80825.1 - 0.00018 22.0 17.9 0.11 13.1 1.0 5.5 4 2 1 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS80825.1 - 0.00024 21.3 4.4 0.053 13.8 0.5 3.6 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 ETS80825.1 - 0.013 15.6 12.3 3.9 7.8 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 ETS80825.1 - 0.033 14.5 12.8 4.7 7.6 1.1 5.9 4 2 2 7 7 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 ETS80825.1 - 0.033 13.8 0.9 0.66 9.6 0.0 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_14 PF13428.6 ETS80825.1 - 0.076 13.9 20.4 42 5.3 0.3 8.0 9 2 2 11 11 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 ETS80825.1 - 0.15 12.7 13.9 2.2 9.0 1.3 5.0 4 1 0 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 ETS80825.1 - 0.32 10.4 4.5 0.43 9.9 2.1 2.3 2 1 0 2 2 2 0 Coatomer epsilon subunit TPR_1 PF00515.28 ETS80825.1 - 5 7.1 6.4 15 5.6 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 ETS80825.1 - 9 6.7 13.0 6.8 7.1 0.3 4.2 3 2 0 4 4 4 0 Bacterial transcriptional activator domain Sec7 PF01369.20 ETS80826.1 - 3.9e-31 108.1 0.0 6.5e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 ETS80826.1 - 7.3e-05 23.2 0.1 0.00021 21.8 0.1 1.9 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 ETS80826.1 - 0.0077 16.6 0.1 0.017 15.5 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Peptidase_M14 PF00246.24 ETS80827.1 - 2.8e-69 234.1 0.1 3.9e-69 233.6 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF3346 PF11826.8 ETS80827.1 - 0.13 12.1 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3346) PIH1_CS PF18201.1 ETS80827.1 - 0.17 12.3 0.0 1.5 9.2 0.0 2.2 2 0 0 2 2 2 0 PIH1 CS-like domain MAPEG PF01124.18 ETS80828.1 - 6.6e-24 84.3 1.5 7.7e-24 84.1 1.5 1.0 1 0 0 1 1 1 1 MAPEG family TFIIE_alpha PF02002.17 ETS80829.1 - 5.2e-14 52.0 0.2 1e-13 51.0 0.2 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit DNA_pol_B_palm PF14792.6 ETS80830.1 - 1.3e-20 73.7 0.0 2.5e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 ETS80830.1 - 1.3e-20 73.3 0.0 3.5e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 ETS80830.1 - 2.2e-20 72.2 0.2 5.5e-20 70.9 0.2 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 ETS80830.1 - 1.1e-09 38.5 0.0 2e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 ETS80830.1 - 0.017 15.7 0.0 1.2 9.8 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain BRCT_2 PF16589.5 ETS80830.1 - 0.02 15.3 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain NTP_transf_2 PF01909.23 ETS80830.1 - 0.037 14.3 0.2 0.16 12.2 0.0 2.1 1 1 1 2 2 2 0 Nucleotidyltransferase domain Golgin_A5 PF09787.9 ETS80831.1 - 0.012 15.1 0.1 0.017 14.6 0.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Myb_DNA-binding PF00249.31 ETS80833.1 - 1.6e-23 82.6 2.7 5.3e-13 48.9 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ETS80833.1 - 6.5e-15 55.1 3.2 3.2e-11 43.3 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Glyco_transf_41 PF13844.6 ETS80834.1 - 1.1e-103 347.2 0.0 1e-52 179.2 0.0 3.3 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 ETS80834.1 - 2.6e-20 71.3 11.0 0.00029 20.5 0.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 ETS80834.1 - 5.7e-16 57.3 9.7 0.039 14.1 0.1 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 ETS80834.1 - 2.7e-13 49.4 9.1 0.0072 16.0 0.1 6.5 4 1 2 6 6 6 4 TPR repeat TPR_8 PF13181.6 ETS80834.1 - 1.8e-10 40.1 3.0 0.34 11.2 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 ETS80834.1 - 3.8e-10 39.4 0.4 0.046 14.1 0.0 5.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 ETS80834.1 - 1.9e-09 37.1 6.7 0.016 15.1 0.3 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 ETS80834.1 - 2.3e-08 34.2 5.8 0.018 15.3 0.1 4.9 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 ETS80834.1 - 1.7e-06 27.7 0.3 0.067 13.3 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 ETS80834.1 - 0.00018 22.1 12.3 0.6 11.1 0.0 6.9 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS80834.1 - 0.00031 21.2 0.7 2.4 8.7 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ETS80834.1 - 0.024 15.3 8.1 13 6.5 0.0 5.4 5 1 1 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS80834.1 - 0.077 13.2 1.4 1.2 9.4 0.6 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Ribosomal_L11_N PF03946.14 ETS80835.1 - 5.3e-20 71.0 0.6 1.7e-15 56.6 0.1 2.3 2 0 0 2 2 2 2 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ETS80835.1 - 2.6e-17 63.1 0.5 4.4e-17 62.3 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.15 ETS80836.1 - 2e-82 276.4 0.0 2.8e-82 275.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 ETS80836.1 - 1.7e-29 102.4 0.4 3.3e-29 101.5 0.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 ETS80836.1 - 1.7e-25 88.8 0.1 4.5e-25 87.4 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 ETS80836.1 - 4.9e-16 58.5 5.2 9.3e-16 57.6 5.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ETS80836.1 - 4.9e-15 55.2 0.0 1.2e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 ETS80836.1 - 0.04 13.3 0.7 0.091 12.2 0.1 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain WW PF00397.26 ETS80837.1 - 0.00098 19.2 1.2 0.0015 18.6 0.1 2.0 2 0 0 2 2 2 1 WW domain Dehydrin PF00257.19 ETS80837.1 - 0.024 15.2 6.3 0.04 14.5 6.3 1.4 1 0 0 1 1 1 0 Dehydrin DUF3826 PF12875.7 ETS80837.1 - 0.099 12.8 0.7 0.15 12.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) CDC45 PF02724.14 ETS80837.1 - 0.41 8.9 6.9 0.53 8.5 6.9 1.0 1 0 0 1 1 1 0 CDC45-like protein CAML PF14963.6 ETS80837.1 - 1.3 9.1 5.6 1.8 8.6 5.6 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF3827 PF12877.7 ETS80837.1 - 2.8 6.2 7.2 3.8 5.8 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) ADIP PF11559.8 ETS80838.1 - 4.3 7.4 16.2 6 6.9 4.5 2.8 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding 4HBT_2 PF13279.6 ETS80839.1 - 9.8e-12 45.4 0.1 1.3e-11 45.0 0.1 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Abhydrolase_3 PF07859.13 ETS80839.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Methyltransf_25 PF13649.6 ETS80840.1 - 1.7e-12 47.9 0.0 3.9e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS80840.1 - 9.6e-09 35.8 0.0 2.6e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS80840.1 - 5.4e-08 32.9 0.0 1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS80840.1 - 1.4e-05 24.9 0.0 3e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS80840.1 - 0.0024 17.2 0.0 0.024 14.0 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ETS80840.1 - 0.0031 18.2 0.0 0.01 16.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Exo_endo_phos PF03372.23 ETS80841.1 - 3.8e-18 65.9 2.6 1.8e-17 63.6 2.6 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 ETS80841.1 - 3.9e-11 42.5 10.1 3.4e-08 33.1 0.4 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ETS80841.1 - 6.2e-11 42.4 5.6 3.7e-06 27.2 0.2 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ETS80841.1 - 0.0049 17.2 8.4 0.04 14.5 0.4 4.8 6 0 0 6 6 6 1 Leucine Rich Repeat TFIIA PF03153.13 ETS80841.1 - 0.0083 16.2 17.6 0.015 15.4 17.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit LRR_9 PF14580.6 ETS80841.1 - 0.049 13.1 0.5 0.097 12.2 0.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeat MFS_1 PF07690.16 ETS80842.1 - 2.7e-23 82.5 76.9 2.2e-17 63.0 47.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Spherulin4 PF12138.8 ETS80843.1 - 3e-40 138.4 0.0 3.9e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Spherulation-specific family 4 Alpha_GJ PF03229.13 ETS80844.1 - 4.1 8.0 19.0 5.3 7.6 19.0 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J FSA_C PF10479.9 ETS80844.1 - 8 4.5 11.5 8.5 4.4 11.5 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus AAA_29 PF13555.6 ETS80845.1 - 4.7e-05 23.1 0.0 9.8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 ETS80845.1 - 0.00012 22.6 0.2 0.00035 21.1 0.1 1.8 2 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 ETS80845.1 - 0.00068 19.9 0.0 0.0018 18.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ETS80845.1 - 0.0035 17.9 0.0 0.0098 16.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ETS80845.1 - 0.0058 16.7 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF87 PF01935.17 ETS80845.1 - 0.0091 16.1 0.1 0.019 15.0 0.1 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 ETS80845.1 - 0.08 12.3 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ploopntkinase3 PF18751.1 ETS80845.1 - 0.13 12.2 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_21 PF13304.6 ETS80845.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Cnl2_NKP2 PF09447.10 ETS80845.1 - 0.17 12.0 0.1 0.38 10.9 0.1 1.5 1 0 0 1 1 1 0 Cnl2/NKP2 family protein WD40 PF00400.32 ETS80846.1 - 3.1e-51 170.2 17.5 4.9e-08 33.5 0.0 8.5 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS80846.1 - 3.5e-10 40.0 0.1 0.0012 19.1 0.0 4.4 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ETS80846.1 - 3.8e-08 32.5 0.1 0.00021 20.1 0.0 3.9 4 0 0 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ETS80846.1 - 2.5e-05 23.2 0.0 0.15 10.8 0.0 3.2 3 0 0 3 3 3 3 Nup133 N terminal like LisH_TPL PF17814.1 ETS80846.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 LisH-like dimerisation domain CLASP_N PF12348.8 ETS80847.1 - 9.9e-05 22.0 0.0 0.0058 16.2 0.0 2.4 2 0 0 2 2 2 1 CLASP N terminal Cnd1 PF12717.7 ETS80847.1 - 0.0014 18.7 0.0 0.15 12.1 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Syntaxin PF00804.25 ETS80847.1 - 0.0036 17.0 4.9 0.011 15.4 4.9 1.8 1 0 0 1 1 1 1 Syntaxin HEAT PF02985.22 ETS80847.1 - 0.0083 16.3 8.0 1.4 9.4 0.1 5.3 5 0 0 5 5 5 1 HEAT repeat TAN PF11640.8 ETS80847.1 - 0.013 15.6 0.1 0.013 15.6 0.1 2.3 2 1 0 2 2 2 0 Telomere-length maintenance and DNA damage repair MMS19_N PF14500.6 ETS80847.1 - 0.017 14.7 0.0 1.3 8.6 0.0 3.0 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Fez1 PF06818.15 ETS80847.1 - 0.19 12.2 11.7 0.51 10.8 11.7 1.7 1 0 0 1 1 1 0 Fez1 HALZ PF02183.18 ETS80847.1 - 0.29 11.4 12.7 0.26 11.5 2.8 3.0 3 0 0 3 3 2 0 Homeobox associated leucine zipper TMCO5 PF14992.6 ETS80847.1 - 0.9 9.1 11.1 1.5 8.3 11.1 1.3 1 0 0 1 1 1 0 TMCO5 family ADIP PF11559.8 ETS80847.1 - 1.3 9.0 15.7 3.7 7.6 15.7 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF5101 PF17031.5 ETS80847.1 - 2 8.5 4.1 4 7.6 1.5 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5101) FUSC PF04632.12 ETS80847.1 - 2.2 6.7 5.2 4.5 5.7 5.2 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family YabA PF06156.13 ETS80847.1 - 3.3 8.4 8.3 78 4.0 8.3 2.7 1 1 0 1 1 1 0 Initiation control protein YabA GAS PF13851.6 ETS80847.1 - 5.9 6.2 16.1 26 4.1 16.1 2.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 ETS80847.1 - 8.5 5.2 12.0 17 4.2 12.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein FPP PF05911.11 ETS80847.1 - 8.7 4.4 13.2 15 3.6 13.2 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Amidohydro_1 PF01979.20 ETS80848.1 - 1.8e-42 145.9 0.0 2.1e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS80848.1 - 6.2e-19 68.8 2.1 8.9e-13 48.5 0.1 2.5 2 1 0 2 2 2 2 Amidohydrolase family Pterin_bind PF00809.22 ETS80848.1 - 0.012 15.3 0.1 0.019 14.6 0.1 1.2 1 0 0 1 1 1 0 Pterin binding enzyme Abhydrolase_1 PF00561.20 ETS80852.1 - 1.2e-18 67.7 0.3 1.1e-17 64.6 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS80852.1 - 8.5e-16 59.2 1.0 1.3e-15 58.6 1.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 ETS80852.1 - 2e-07 30.0 0.0 3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 ETS80852.1 - 2e-06 27.3 0.0 2.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1100 PF06500.11 ETS80852.1 - 0.0048 15.7 0.0 0.0066 15.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Acetyltransf_3 PF13302.7 ETS80853.1 - 1.4e-12 48.4 0.0 2.4e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS80853.1 - 0.00022 21.4 0.0 0.00036 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 ETS80853.1 - 0.0052 16.9 0.0 0.0084 16.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SAPS PF04499.15 ETS80854.1 - 2.3e-188 627.0 0.0 2.3e-188 627.0 0.0 2.7 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein Abhydrolase_3 PF07859.13 ETS80855.1 - 2.1e-13 50.6 0.1 3.7e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Condensation PF00668.20 ETS80856.1 - 2.6e-79 267.0 0.0 1.3e-33 116.4 0.0 3.6 3 1 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 ETS80856.1 - 2e-31 109.1 0.0 2.7e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 ETS80856.1 - 7e-14 51.9 1.1 0.0015 18.8 0.0 4.1 3 0 0 3 3 3 3 Phosphopantetheine attachment site MFS_1 PF07690.16 ETS80857.1 - 3.7e-37 128.1 31.3 3.7e-37 128.1 31.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily GHMP_kinases_N PF00288.26 ETS80857.1 - 0.014 15.6 0.9 0.086 13.1 0.3 2.4 2 0 0 2 2 2 0 GHMP kinases N terminal domain NEMP PF10225.9 ETS80857.1 - 0.088 12.5 4.3 0.27 10.9 4.3 1.8 1 0 0 1 1 1 0 NEMP family DUF2070 PF09843.9 ETS80857.1 - 0.31 9.3 8.9 0.51 8.6 8.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF5090 PF17009.5 ETS80857.1 - 0.94 9.4 4.5 2 8.4 4.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) DUF4148 PF13663.6 ETS80857.1 - 1.2 9.4 4.6 4.5 7.5 4.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) FMO-like PF00743.19 ETS80858.1 - 1.6e-28 99.4 0.0 2.3e-18 65.9 0.1 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ETS80858.1 - 1.4e-14 54.0 0.1 3.9e-08 32.9 0.0 3.3 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS80858.1 - 5.8e-09 35.6 0.0 1.2e-06 28.0 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS80858.1 - 4e-08 33.4 0.0 8.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS80858.1 - 2.4e-06 27.4 0.6 0.00014 21.5 0.5 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS80858.1 - 5e-06 26.6 0.1 4e-05 23.7 0.1 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 ETS80858.1 - 8.8e-05 21.8 0.2 0.07 12.3 0.0 3.2 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 ETS80858.1 - 0.0026 18.3 0.3 0.018 15.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS80858.1 - 0.013 14.3 0.2 0.035 12.8 0.6 1.5 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 ETS80858.1 - 0.087 11.9 0.3 0.14 11.2 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 ETS80858.1 - 0.11 11.3 0.1 0.24 10.2 0.1 1.5 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 ETS80858.1 - 0.13 11.5 0.1 0.42 9.8 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Semialdhyde_dh PF01118.24 ETS80858.1 - 0.13 12.7 0.0 0.39 11.2 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 ETS80858.1 - 0.14 11.6 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 ETS80858.1 - 0.19 11.8 0.0 7.3 6.7 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase AA_permease PF00324.21 ETS80860.1 - 1.4e-142 475.7 42.4 1.6e-142 475.5 42.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS80860.1 - 1.4e-37 129.5 45.5 1.9e-37 129.1 45.5 1.1 1 0 0 1 1 1 1 Amino acid permease FAD_binding_4 PF01565.23 ETS80861.1 - 2e-21 76.2 1.3 3.6e-21 75.4 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS80861.1 - 0.078 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like OPT PF03169.15 ETS80862.1 - 3e-171 571.2 53.5 3.5e-171 571.0 53.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3818 PF12825.7 ETS80863.1 - 3.9e-48 164.2 0.6 4e-45 154.3 0.0 2.8 2 1 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 ETS80863.1 - 3e-38 130.8 0.0 5.9e-38 129.8 0.0 1.5 1 0 0 1 1 1 1 PX-associated Metal_resist PF13801.6 ETS80863.1 - 0.22 11.7 1.1 1.1 9.4 0.3 2.3 2 0 0 2 2 2 0 Heavy-metal resistance Peptidase_S10 PF00450.22 ETS80864.1 - 3.6e-86 290.2 0.0 9.5e-86 288.8 0.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase CMD PF02627.20 ETS80865.1 - 2.1e-22 78.9 0.0 3e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family HAUS4 PF14735.6 ETS80866.1 - 0.00013 21.8 0.6 0.00025 20.8 0.6 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 Ribosomal_L28 PF00830.19 ETS80867.1 - 1.2e-15 57.4 0.4 1.9e-15 56.8 0.4 1.3 1 0 0 1 1 1 1 Ribosomal L28 family Trp_syntA PF00290.20 ETS80868.1 - 3.6e-98 327.6 0.0 6.1e-98 326.8 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 ETS80868.1 - 6.5e-48 163.6 2.2 1.1e-47 162.9 2.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Aminotran_1_2 PF00155.21 ETS80869.1 - 1.1e-91 307.8 0.0 1.3e-91 307.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_transf_8C PF08437.10 ETS80869.1 - 0.1 12.7 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal Tyrosinase PF00264.20 ETS80870.1 - 8.7e-34 117.7 2.2 1.8e-32 113.4 2.2 2.1 1 1 0 1 1 1 1 Common central domain of tyrosinase HD PF01966.22 ETS80872.1 - 0.0067 16.6 0.3 0.012 15.8 0.3 1.5 1 0 0 1 1 1 1 HD domain adh_short PF00106.25 ETS80873.1 - 1.8e-19 70.0 0.0 1.5e-15 57.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS80873.1 - 2.7e-10 40.2 0.0 6.1e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS80873.1 - 1.4e-08 34.8 0.1 2.2e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS80873.1 - 0.11 11.9 0.2 0.19 11.1 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1674 PF07896.12 ETS80874.1 - 4.4e-18 65.5 3.3 4.4e-18 65.5 3.3 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1674) Rxt3 PF08642.10 ETS80875.1 - 1.9e-41 141.8 0.0 1.3e-40 139.1 0.0 2.4 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 ETS80875.1 - 0.00018 21.5 0.0 0.0028 17.7 0.0 2.2 2 0 0 2 2 2 1 LCCL domain NicO PF03824.16 ETS80875.1 - 0.95 8.7 2.7 1.8 7.8 2.7 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein MFS_1 PF07690.16 ETS80876.1 - 2.4e-32 112.3 33.0 2.4e-32 112.3 33.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS80877.1 - 4.7e-47 160.9 27.0 4e-45 154.5 27.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS80877.1 - 2.2e-16 59.7 35.5 1.5e-08 33.9 8.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OPT PF03169.15 ETS80878.1 - 7.5e-166 553.4 55.1 8.6e-166 553.2 55.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SNARE PF05739.19 ETS80878.1 - 0.011 15.7 1.6 0.19 11.7 0.0 2.6 2 0 0 2 2 2 0 SNARE domain DUF2427 PF10348.9 ETS80878.1 - 0.094 12.5 4.1 0.24 11.2 1.8 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) Glyco_hydro_28 PF00295.17 ETS80879.1 - 3.5e-50 170.9 13.3 4.7e-50 170.5 13.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 p450 PF00067.22 ETS80880.1 - 1.5e-50 172.4 0.0 1.9e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 ETS80881.1 - 8.2e-22 77.6 25.3 8.2e-22 77.6 25.3 2.2 2 1 1 3 3 3 1 Major Facilitator Superfamily PRKCSH PF07915.13 ETS80882.1 - 7.7e-21 74.9 0.1 2.7e-20 73.2 0.0 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Secapin PF17521.2 ETS80882.1 - 0.014 15.2 2.4 0.71 9.7 1.5 2.6 2 0 0 2 2 2 0 Honey bee peptides PRKCSH_1 PF13015.6 ETS80882.1 - 0.069 12.8 0.0 4.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein DDDD PF10161.9 ETS80884.1 - 0.12 12.1 0.6 8.4 6.2 0.0 3.4 4 0 0 4 4 4 0 Putative mitochondrial precursor protein DUF2207 PF09972.9 ETS80884.1 - 0.13 11.0 2.7 2.4 6.8 0.0 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Sensor PF13796.6 ETS80884.1 - 0.32 11.0 4.7 0.067 13.2 1.0 1.7 2 0 0 2 2 2 0 Putative sensor DPBB_1 PF03330.18 ETS80886.1 - 2.5e-05 24.5 0.0 4.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ETS80886.1 - 0.0066 16.3 0.4 0.011 15.6 0.4 1.3 1 0 0 1 1 1 1 Barwin family UL42 PF17638.2 ETS80886.1 - 0.095 12.7 1.9 0.78 9.7 2.4 2.1 2 0 0 2 2 2 0 HCMV UL42 RskA PF10099.9 ETS80886.1 - 4.7 7.5 11.5 1.2e+02 2.9 12.0 2.2 1 1 0 1 1 1 0 Anti-sigma-K factor rskA FMN_dh PF01070.18 ETS80887.1 - 7.1e-81 271.9 0.1 1.2e-47 162.6 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ETS80887.1 - 0.00012 21.4 0.0 0.02 14.0 0.0 2.1 2 0 0 2 2 2 2 Conserved region in glutamate synthase IMPDH PF00478.25 ETS80887.1 - 0.00014 21.0 0.0 0.00069 18.7 0.0 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 ETS80887.1 - 0.00024 20.6 0.2 0.00033 20.2 0.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 ETS80887.1 - 0.021 14.3 0.2 1.9 7.9 0.0 2.5 1 1 1 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.21 ETS80887.1 - 0.043 13.0 0.1 0.78 8.9 0.0 2.1 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 ETS80887.1 - 0.11 11.9 0.0 0.44 9.9 0.0 1.9 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator AP_endonuc_2 PF01261.24 ETS80888.1 - 5e-30 104.5 0.0 6.4e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Peptidase_M85 PF13678.6 ETS80888.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 NFkB-p65-degrading zinc protease CDC37_M PF08565.11 ETS80889.1 - 0.17 11.8 2.3 0.77 9.7 0.4 2.5 1 1 2 3 3 3 0 Cdc37 Hsp90 binding domain Jnk-SapK_ap_N PF09744.9 ETS80889.1 - 0.72 10.1 4.7 4 7.6 0.3 2.5 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Casc1_N PF15927.5 ETS80889.1 - 0.79 9.4 6.2 0.98 9.1 1.7 2.5 1 1 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus ABC_tran_CTD PF16326.5 ETS80889.1 - 0.79 10.0 9.4 0.99 9.7 0.2 3.2 3 1 0 3 3 3 0 ABC transporter C-terminal domain TMF_DNA_bd PF12329.8 ETS80889.1 - 1.4 8.9 7.5 15 5.6 0.2 3.8 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.6 ETS80889.1 - 2.6 7.8 7.3 8.7 6.0 2.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DHR10 PF18595.1 ETS80889.1 - 4.4 7.4 10.1 5.8 7.0 0.2 3.3 2 2 1 3 3 3 0 Designed helical repeat protein 10 domain DivIC PF04977.15 ETS80889.1 - 4.6 7.1 5.6 16 5.4 0.2 3.3 3 1 1 4 4 4 0 Septum formation initiator IL17 PF06083.11 ETS80890.1 - 0.081 13.4 0.1 0.27 11.7 0.1 1.9 1 0 0 1 1 1 0 Interleukin-17 Cutinase PF01083.22 ETS80891.1 - 1.1e-45 155.7 1.3 1.4e-45 155.5 1.3 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 ETS80891.1 - 0.016 15.1 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 ETS80891.1 - 0.025 14.2 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PE-PPE PF08237.11 ETS80891.1 - 0.027 14.0 0.1 0.038 13.5 0.1 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_2 PF02230.16 ETS80891.1 - 0.1 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase adh_short PF00106.25 ETS80892.1 - 2e-07 30.7 0.0 3.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS80892.1 - 2e-05 24.2 0.0 4.9e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS80892.1 - 0.0014 18.6 0.2 0.017 15.0 0.1 2.3 1 1 1 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.8 ETS80892.1 - 0.022 14.5 2.0 0.038 13.7 0.4 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PH_4 PF15404.6 ETS80892.1 - 0.098 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain DUF4382 PF14321.6 ETS80892.1 - 0.12 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4382) NAD_binding_10 PF13460.6 ETS80893.1 - 4.1e-08 33.3 0.0 1.4e-06 28.3 0.0 2.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS80893.1 - 0.0002 21.0 0.0 0.0031 17.1 0.0 2.5 3 0 0 3 3 3 1 NmrA-like family Fungal_trans PF04082.18 ETS80894.1 - 2.6e-06 26.7 0.4 5.4e-06 25.6 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2OG-FeII_Oxy_2 PF13532.6 ETS80895.1 - 6.5e-15 55.8 0.0 8.7e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 ETS80895.1 - 2.8e-05 24.5 0.0 5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cnn_1N PF07989.11 ETS80896.1 - 3.3e-08 33.6 10.3 3.3e-08 33.6 10.3 2.3 1 1 1 2 2 2 1 Centrosomin N-terminal motif 1 AHH PF14412.6 ETS80896.1 - 0.087 12.9 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH UPF0242 PF06785.11 ETS80896.1 - 0.56 10.3 9.5 0.38 10.8 6.7 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HhH-GPD PF00730.25 ETS80897.1 - 4.3e-11 43.2 0.0 1.1e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ETS80897.1 - 0.045 13.7 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Med3 PF11593.8 ETS80897.1 - 2.5 7.2 6.9 3.5 6.7 6.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FAD_binding_4 PF01565.23 ETS80898.1 - 1.1e-21 77.0 0.1 1.8e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS80898.1 - 0.001 19.1 0.0 0.001 19.1 0.0 2.5 3 0 0 3 3 3 1 Berberine and berberine like Peptidase_M28 PF04389.17 ETS80899.1 - 5.4e-34 117.6 0.0 8e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ETS80899.1 - 2.7e-08 33.8 0.0 4.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 ETS80899.1 - 5e-05 22.9 0.1 0.00017 21.2 0.0 1.9 2 0 0 2 2 2 1 Nicastrin Peptidase_M42 PF05343.14 ETS80899.1 - 0.00018 20.6 0.1 0.037 13.0 0.0 2.6 2 1 0 2 2 2 2 M42 glutamyl aminopeptidase DUF192 PF02643.15 ETS80899.1 - 0.13 12.4 0.0 0.54 10.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized ACR, COG1430 DNA_methylase PF00145.17 ETS80900.1 - 3.4e-40 138.4 0.0 4.2e-30 105.2 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Cons_hypoth95 PF03602.15 ETS80900.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Gon7 PF08738.10 ETS80901.1 - 1.8e-08 34.4 6.9 9.4e-08 32.1 6.9 2.1 1 1 0 1 1 1 1 Gon7 family Vps39_1 PF10366.9 ETS80902.1 - 9e-32 109.6 3.0 2.1e-31 108.4 0.0 3.2 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 ETS80902.1 - 9.3e-29 100.1 0.0 2.4e-28 98.7 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 ETS80902.1 - 2.3e-16 60.2 0.0 4.4e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 ETS80902.1 - 2.6e-05 24.1 4.4 0.0023 17.8 0.2 3.2 3 0 0 3 3 3 2 Region in Clathrin and VPS TPR_1 PF00515.28 ETS80902.1 - 0.011 15.5 1.6 0.67 9.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Miff PF05644.11 ETS80902.1 - 0.026 14.1 0.8 1.2 8.7 0.9 2.6 2 1 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff DUF2052 PF09747.9 ETS80902.1 - 0.11 12.6 4.2 0.66 10.1 2.7 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) ANAPC3 PF12895.7 ETS80902.1 - 0.73 10.1 2.8 1.2e+02 3.0 0.0 3.9 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 ETS80902.1 - 2.8 8.3 4.4 31 5.0 0.3 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Mito_carr PF00153.27 ETS80903.1 - 2.9e-49 165.0 5.0 8.1e-17 60.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein US6 PF17616.2 ETS80904.1 - 0.054 13.4 1.1 0.083 12.8 0.5 1.5 2 0 0 2 2 2 0 Viral unique short region 6 Sugar_tr PF00083.24 ETS80906.1 - 9.9e-102 341.1 30.8 1.2e-101 340.8 30.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS80906.1 - 1.6e-21 76.7 42.8 4.3e-20 72.0 25.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 ETS80906.1 - 0.0018 16.6 0.8 0.0034 15.7 0.8 1.4 1 0 0 1 1 1 1 BT1 family PetL PF05115.14 ETS80906.1 - 4.1 7.5 8.8 0.37 10.8 2.4 2.8 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) FAD_binding_3 PF01494.19 ETS80907.1 - 1e-16 61.2 0.4 1.7e-10 40.7 0.3 3.3 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS80907.1 - 0.0022 18.2 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ETS80907.1 - 0.0037 16.2 0.5 0.036 12.9 0.0 2.4 3 0 0 3 3 3 1 Tryptophan halogenase DAO PF01266.24 ETS80907.1 - 0.0076 15.9 0.0 0.065 12.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS80907.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS80907.1 - 0.12 11.4 1.2 0.44 9.5 0.2 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 ETS80907.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain SPX PF03105.19 ETS80908.1 - 3e-44 152.5 0.1 2.6e-31 109.9 0.0 2.1 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 ETS80908.1 - 1.8e-38 132.8 39.7 2.7e-38 132.2 39.7 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 ETS80908.1 - 1.6e-32 112.9 55.9 1.8e-27 96.4 35.2 2.7 1 1 2 3 3 3 2 Citrate transporter TFIIA_gamma_N PF02268.16 ETS80908.1 - 0.052 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain Cytochrome-c551 PF10643.9 ETS80908.1 - 9.5 5.7 7.4 1.6 8.3 1.4 2.5 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 HbrB PF08539.11 ETS80909.1 - 3.1e-51 173.7 0.0 1e-50 172.1 0.0 1.9 2 0 0 2 2 2 1 HbrB-like LIM_bind PF01803.16 ETS80910.1 - 9.3e-57 192.3 0.1 9.3e-57 192.3 0.1 6.3 2 1 1 3 3 3 1 LIM-domain binding protein SKG6 PF08693.10 ETS80911.1 - 2e-07 30.3 2.9 4.6e-07 29.1 2.9 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 ETS80911.1 - 0.00012 21.9 0.1 0.00021 21.1 0.1 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Rax2 PF12768.7 ETS80911.1 - 0.04 13.4 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Caps_synth PF05704.12 ETS80912.1 - 1.6e-12 47.4 0.0 2.4e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 ETS80912.1 - 0.00011 22.7 0.0 0.00021 21.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Atg8 PF02991.16 ETS80915.1 - 2.8e-51 172.0 0.2 3.3e-51 171.8 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 ETS80915.1 - 3.1e-06 27.5 0.0 3.7e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 adh_short PF00106.25 ETS80916.1 - 1.3e-08 34.6 0.0 1.5e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS80916.1 - 1.4e-08 34.6 0.0 1.9e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_hydro_64 PF16483.5 ETS80917.1 - 4.8e-118 394.6 0.0 5.6e-118 394.4 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase Git3 PF11710.8 ETS80918.1 - 6e-10 39.2 16.2 8e-10 38.8 9.8 2.9 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 ETS80918.1 - 6.9e-05 22.3 10.8 0.0046 16.3 5.7 2.9 2 1 1 3 3 3 2 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 ETS80918.1 - 0.0049 16.0 9.7 0.01 15.0 9.7 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor SCIMP PF15050.6 ETS80918.1 - 0.046 14.2 0.4 2.9 8.4 0.3 2.5 2 0 0 2 2 2 0 SCIMP protein Ni_hydr_CYTB PF01292.20 ETS80918.1 - 0.051 13.2 8.0 0.12 12.0 6.8 2.0 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 ANAPC4_WD40 PF12894.7 ETS80919.1 - 4.4e-05 23.7 0.4 0.42 10.9 0.1 2.9 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PAM2 PF07145.15 ETS80919.1 - 0.0004 19.9 0.0 0.00098 18.7 0.0 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region WD40 PF00400.32 ETS80919.1 - 0.00049 20.9 3.8 0.19 12.7 0.1 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS80920.1 - 0.018 15.3 0.0 0.056 13.8 0.0 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain PPTA PF01239.22 ETS80923.1 - 2.3e-37 125.6 14.7 1.1e-08 34.6 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat GlutR_dimer PF00745.20 ETS80923.1 - 0.24 11.9 2.4 15 6.1 0.0 2.9 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain ADH_zinc_N PF00107.26 ETS80924.1 - 1.9e-12 47.3 0.3 3.7e-12 46.3 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS80924.1 - 6e-07 30.6 0.1 2.4e-06 28.7 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS80924.1 - 0.00018 21.4 0.2 0.16 11.9 0.0 2.8 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ETS80924.1 - 0.0014 18.5 0.1 0.0035 17.2 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase His_Phos_2 PF00328.22 ETS80925.1 - 0.0013 18.1 0.1 0.053 12.9 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Glyco_hydro_76 PF03663.14 ETS80926.1 - 1.6e-52 179.3 4.4 1.9e-52 179.0 4.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 ETS80926.1 - 3.7e-07 29.6 0.0 7.5e-06 25.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 ETS80926.1 - 0.0078 14.8 0.0 0.29 9.6 0.0 2.1 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 DUF588 PF04535.12 ETS80927.1 - 2.8 7.7 10.3 1.6 8.5 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF588) Oxidored_FMN PF00724.20 ETS80928.1 - 8.2e-65 219.3 0.0 9.5e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 ETS80928.1 - 3e-05 23.3 0.2 0.00034 19.8 0.1 2.4 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) DUF1611_N PF17396.2 ETS80928.1 - 0.0058 16.8 0.1 0.58 10.4 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1611_N) Rossmann-like domain His_biosynth PF00977.21 ETS80928.1 - 0.013 14.9 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.21 ETS80928.1 - 0.061 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase FMN_dh PF01070.18 ETS80928.1 - 0.13 11.3 0.7 0.77 8.7 0.2 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase IMPDH PF00478.25 ETS80928.1 - 0.17 10.9 0.5 8.6 5.3 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DUF3169 PF11368.8 ETS80929.1 - 0.66 9.4 2.8 0.41 10.1 0.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) Fer2 PF00111.27 ETS80930.1 - 6.7e-06 26.0 0.7 1.3e-05 25.1 0.7 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 ETS80930.1 - 2.9e-05 24.7 0.0 5.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ETS80930.1 - 0.0067 16.6 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain adh_short PF00106.25 ETS80931.1 - 9.6e-31 106.8 0.0 4.9e-24 84.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS80931.1 - 2e-21 76.6 0.0 3.1e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS80931.1 - 3.2e-10 40.2 0.0 5.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS80931.1 - 0.017 14.6 0.1 0.038 13.4 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ETS80931.1 - 0.047 12.8 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ETS80931.1 - 0.084 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ETS80931.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Fungal_trans PF04082.18 ETS80932.1 - 1.5e-25 89.7 0.0 2.3e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SET PF00856.28 ETS80933.1 - 1.6e-07 31.9 0.0 2.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 SET domain Nup96 PF12110.8 ETS80934.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Nuclear protein 96 T4BSS_DotI_IcmL PF11393.8 ETS80935.1 - 0.03 13.8 0.3 0.044 13.3 0.1 1.5 1 1 0 1 1 1 0 Type-IV b secretion system, inner-membrane complex component cNMPbd_u2 PF16643.5 ETS80936.1 - 0.15 12.5 4.6 0.071 13.6 2.2 1.6 2 0 0 2 2 2 0 Unstructured region on cNMP-binding protein SHR-BD PF06650.12 ETS80937.1 - 4.5e-98 327.9 0.0 2.1e-93 312.7 0.0 2.9 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 ETS80937.1 - 4.8e-97 324.0 21.4 2e-92 308.9 1.4 6.9 8 0 0 8 8 8 4 Repeating coiled region of VPS13 VPS13 PF16908.5 ETS80937.1 - 1.3e-88 296.8 0.9 8.7e-86 287.5 0.0 3.8 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 ETS80937.1 - 2.2e-75 252.4 7.4 1.7e-70 236.4 0.8 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 ETS80937.1 - 1.8e-40 137.7 0.0 7.5e-40 135.7 0.0 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 ETS80937.1 - 2.6e-07 30.9 0.0 1.6e-06 28.4 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain DUF3429 PF11911.8 ETS80938.1 - 1.4e-44 151.9 10.2 1.9e-44 151.5 10.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF3537 PF12056.8 ETS80938.1 - 0.035 12.9 2.1 0.16 10.8 2.8 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3537) DUF4834 PF16118.5 ETS80938.1 - 0.039 14.9 2.8 0.039 14.9 2.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) EamA PF00892.20 ETS80938.1 - 0.087 13.0 5.3 0.26 11.4 1.5 2.2 1 1 1 2 2 2 0 EamA-like transporter family SID-1_RNA_chan PF13965.6 ETS80938.1 - 0.098 11.0 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PRD1_DD PF11087.8 ETS80938.1 - 0.13 12.0 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 PRD1 phage membrane DNA delivery Neur_chan_memb PF02932.16 ETS80938.1 - 0.23 11.5 6.5 0.13 12.3 4.1 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ureide_permease PF07168.11 ETS80938.1 - 5.4 5.7 6.4 56 2.3 8.5 1.8 2 0 0 2 2 2 0 Ureide permease Glycos_transf_1 PF00534.20 ETS80940.1 - 7.8e-20 71.1 0.0 1.7e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ETS80940.1 - 1.9e-15 57.5 0.0 3.6e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ETS80940.1 - 0.00023 21.5 0.0 0.00059 20.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.21 ETS80940.1 - 0.13 10.9 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 20 Globin PF00042.22 ETS80941.1 - 2.4e-08 34.5 0.0 4.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.21 ETS80941.1 - 3.5e-08 34.1 0.0 5.7e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ETS80941.1 - 1.3e-05 25.4 0.0 2.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 ETS80941.1 - 0.0026 17.7 0.0 0.0086 16.0 0.0 1.8 1 1 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 ETS80941.1 - 0.013 15.6 0.2 0.051 13.7 0.1 2.1 2 1 1 3 3 3 0 Ferric reductase NAD binding domain ketoacyl-synt PF00109.26 ETS80942.1 - 3.9e-74 249.4 0.0 1.1e-73 247.9 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ETS80942.1 - 1.8e-46 158.3 0.0 4.3e-46 157.1 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 ETS80942.1 - 3.2e-43 148.1 0.0 5e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ETS80942.1 - 1e-42 146.8 0.1 1.7e-42 146.0 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ETS80942.1 - 8.7e-33 112.8 0.0 4.5e-32 110.6 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 ETS80942.1 - 1.8e-13 50.4 0.0 3e-12 46.4 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 ETS80942.1 - 2.5e-09 37.6 0.0 7e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 ETS80942.1 - 9.4e-05 22.7 0.0 0.00036 20.8 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 ETS80942.1 - 0.0017 17.8 0.0 0.0045 16.4 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Sod_Fe_C PF02777.18 ETS80943.1 - 7.6e-38 128.8 0.4 1.3e-37 128.0 0.2 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ETS80943.1 - 2.3e-30 104.9 1.2 4e-30 104.1 1.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sld5 PF05916.11 ETS80944.1 - 7.9e-16 58.5 0.0 1.4e-15 57.7 0.0 1.4 2 0 0 2 2 2 1 GINS complex protein GCFC PF07842.12 ETS80945.1 - 1.4e-74 251.2 3.1 1.4e-74 251.2 3.1 2.0 1 1 1 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 ETS80945.1 - 7.2e-13 48.2 2.8 1.9e-12 46.9 2.8 1.8 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 ETS80945.1 - 3.2e-09 37.1 13.0 3.2e-09 37.1 13.0 3.6 2 1 1 3 3 3 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 ETS80945.1 - 6.4e-07 29.4 4.2 8.2e-07 29.0 1.2 2.8 2 1 1 3 3 3 1 G-patch domain MFS_1 PF07690.16 ETS80946.1 - 1.6e-32 112.8 30.0 2.5e-32 112.2 30.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily GST_C_3 PF14497.6 ETS80947.1 - 1.7e-31 108.3 0.0 2.8e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ETS80947.1 - 3.4e-05 24.0 0.0 5.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ETS80947.1 - 0.00012 22.0 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2183 PF09949.9 ETS80948.1 - 1.7e-32 111.7 0.0 3.8e-32 110.5 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CLN3 PF02487.17 ETS80949.1 - 2.5e-162 540.5 6.8 2.9e-162 540.3 6.8 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 ETS80949.1 - 0.00037 19.5 11.7 0.00037 19.5 11.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily HPP PF04982.13 ETS80950.1 - 1.4e-39 135.1 6.6 1.4e-39 135.1 6.6 1.6 2 0 0 2 2 2 1 HPP family Tannase PF07519.11 ETS80951.1 - 3e-107 359.4 1.0 3.5e-107 359.2 1.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 ETS80951.1 - 0.0035 17.0 0.2 0.0078 15.9 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS80951.1 - 0.0064 16.0 0.9 0.0064 16.0 0.9 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ETS80951.1 - 0.041 13.1 0.8 0.16 11.2 0.0 2.2 3 0 0 3 3 3 0 Serine aminopeptidase, S33 SLT PF01464.20 ETS80952.1 - 2.1e-06 27.4 1.7 2.1e-05 24.2 1.7 2.0 1 1 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.6 ETS80952.1 - 0.0017 18.1 0.7 0.0038 17.0 0.7 1.5 1 1 0 1 1 1 1 Lysozyme-like Xan_ur_permease PF00860.20 ETS80953.1 - 3.6e-41 141.2 34.3 7.6e-32 110.5 20.3 2.2 2 0 0 2 2 2 2 Permease family MFS_MOT1 PF16983.5 ETS80953.1 - 0.015 15.7 7.1 0.015 15.7 7.1 3.7 2 1 2 4 4 4 0 Molybdate transporter of MFS superfamily Amidohydro_1 PF01979.20 ETS80954.1 - 1.6e-61 208.5 1.1 1.9e-61 208.3 1.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS80954.1 - 1.6e-17 64.1 2.7 1.1e-14 54.8 0.6 2.4 2 1 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 ETS80954.1 - 0.0059 16.0 0.0 0.016 14.5 0.0 1.6 2 0 0 2 2 2 1 Adenosine/AMP deaminase tRNA_bind_3 PF17176.4 ETS80954.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 tRNA-binding domain DUF2397 PF09660.10 ETS80955.1 - 0.011 14.7 2.0 0.015 14.2 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) PIN_8 PF18476.1 ETS80955.1 - 0.027 14.3 1.7 0.043 13.7 1.7 1.2 1 0 0 1 1 1 0 PIN like domain Baculo_PEP_C PF04513.12 ETS80955.1 - 0.083 12.9 1.3 0.16 12.0 1.3 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF445 PF04286.12 ETS80955.1 - 0.094 12.5 2.7 0.14 12.0 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HSBP1 PF06825.12 ETS80955.1 - 0.1 12.5 0.5 0.25 11.2 0.1 1.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 CLZ PF16526.5 ETS80955.1 - 0.54 10.6 3.4 1.5 9.2 3.4 1.8 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ank_2 PF12796.7 ETS80956.1 - 5.3e-25 87.8 0.6 1.1e-10 42.0 0.8 4.4 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS80956.1 - 6.2e-19 66.1 5.0 0.00013 22.1 0.0 7.7 9 0 0 9 9 9 3 Ankyrin repeat Ank_4 PF13637.6 ETS80956.1 - 2.2e-18 66.4 0.7 2.8e-08 34.1 0.0 4.7 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS80956.1 - 1.3e-12 47.7 7.4 0.0021 18.3 0.0 6.2 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 ETS80956.1 - 7.8e-10 38.8 6.1 0.039 14.4 0.3 5.8 5 1 1 6 6 6 2 Ankyrin repeat Osteopontin PF00865.18 ETS80956.1 - 0.067 12.7 4.9 0.11 11.9 4.9 1.3 1 0 0 1 1 1 0 Osteopontin DUF4246 PF14033.6 ETS80957.1 - 2.7e-175 583.8 0.5 3.2e-175 583.6 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 ETS80957.1 - 0.015 15.7 0.0 0.034 14.6 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF2264 PF10022.9 ETS80959.1 - 3.4e-119 398.1 3.3 4.4e-119 397.7 3.3 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) BNR PF02012.20 ETS80959.1 - 0.072 13.1 0.2 0.32 11.2 0.2 2.2 1 0 0 1 1 1 0 BNR/Asp-box repeat MFS_1 PF07690.16 ETS80960.1 - 2.1e-27 96.0 21.2 2.1e-27 96.0 21.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.13 ETS80961.1 - 0.00041 19.5 2.5 0.0018 17.4 1.3 2.4 2 1 0 2 2 2 1 Glycosyl Hydrolase Family 88 Peptidase_M19 PF01244.21 ETS80962.1 - 1.2e-102 343.4 0.0 1.4e-102 343.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Fungal_trans PF04082.18 ETS80963.1 - 6e-16 58.3 1.5 1.4e-15 57.0 1.5 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS80963.1 - 3.1e-05 24.0 7.2 5.9e-05 23.1 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cerato-platanin PF07249.12 ETS80964.1 - 1.7e-06 28.2 1.3 2.1e-06 27.9 0.3 1.7 2 0 0 2 2 2 1 Cerato-platanin DUF1748 PF08520.10 ETS80964.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) Aminotran_3 PF00202.21 ETS80965.1 - 1.3e-81 274.4 0.0 1.6e-81 274.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Pkinase PF00069.25 ETS80966.1 - 3.5e-63 213.4 0.0 5.4e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS80966.1 - 7.4e-29 100.8 0.0 1.2e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ETS80966.1 - 0.027 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 ETS80966.1 - 0.033 14.1 0.0 0.28 11.1 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 ETS80966.1 - 0.061 12.6 0.0 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Actin PF00022.19 ETS80967.1 - 7.9e-112 373.8 0.0 5e-111 371.2 0.0 1.8 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 ETS80967.1 - 0.006 15.8 0.1 0.032 13.4 0.0 2.0 2 0 0 2 2 2 1 Putative actin-like family MreB_Mbl PF06723.13 ETS80967.1 - 0.032 13.0 0.0 0.35 9.7 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein Asp_Glu_race PF01177.22 ETS80968.1 - 5.6e-05 23.1 0.0 0.00012 22.0 0.0 1.5 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Sugar_tr PF00083.24 ETS80969.1 - 2.2e-86 290.5 14.5 3e-86 290.1 14.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS80969.1 - 9.5e-25 87.2 27.2 9.5e-25 87.2 27.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SNN_transmemb PF09049.10 ETS80969.1 - 0.059 13.3 1.0 0.26 11.3 0.1 2.7 2 0 0 2 2 2 0 Stannin transmembrane RPA43_OB PF17875.1 ETS80970.1 - 3.8e-34 118.0 0.2 3.8e-34 118.0 0.2 4.4 3 1 0 3 3 3 1 RPA43 OB domain in RNA Pol I SOBP PF15279.6 ETS80970.1 - 4.8 7.7 13.2 7.9 7.0 13.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein NmrA PF05368.13 ETS80971.1 - 1.1e-27 97.2 0.1 1.3e-27 96.9 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS80971.1 - 5.8e-10 39.4 0.0 4.7e-08 33.1 0.0 3.0 2 1 0 3 3 3 1 NAD(P)H-binding Epimerase PF01370.21 ETS80971.1 - 2.9e-06 26.9 0.0 0.00025 20.6 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS80971.1 - 0.00017 20.7 0.1 0.00041 19.5 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 ETS80971.1 - 0.0053 16.7 0.1 0.0084 16.0 0.1 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 ETS80971.1 - 0.072 12.5 0.0 0.52 9.7 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 ETS80971.1 - 0.11 12.9 0.0 0.45 11.0 0.0 2.1 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Arf PF00025.21 ETS80972.1 - 4.4e-75 250.9 0.2 5e-75 250.8 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ETS80972.1 - 2.6e-14 53.4 0.0 3.7e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ETS80972.1 - 6.6e-13 48.6 0.0 7.3e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 ETS80972.1 - 1.1e-12 47.8 2.0 7.3e-09 35.2 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 ETS80972.1 - 4.3e-12 45.8 0.0 5.4e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ETS80972.1 - 3.9e-11 42.8 0.1 4.9e-11 42.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ETS80972.1 - 0.00028 21.0 0.0 0.00037 20.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Methyltrn_RNA_3 PF02598.17 ETS80972.1 - 0.039 13.5 0.0 0.046 13.2 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methyltransferase 6PF2K PF01591.18 ETS80972.1 - 0.052 12.9 0.1 0.092 12.0 0.1 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.9 ETS80972.1 - 0.065 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas2 DegQ PF08181.11 ETS80972.1 - 0.099 12.8 0.1 0.27 11.4 0.1 1.7 1 0 0 1 1 1 0 DegQ (SacQ) family SpoOE-like PF09388.10 ETS80972.1 - 0.13 12.2 1.0 0.22 11.4 1.0 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein Sugar_tr PF00083.24 ETS80973.1 - 6.6e-127 424.1 21.9 7.7e-127 423.9 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS80973.1 - 2.6e-21 75.9 38.4 1.3e-14 53.9 15.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ilm1 PF10311.9 ETS80973.1 - 0.23 11.1 2.1 0.43 10.2 2.1 1.4 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 MerE PF05052.12 ETS80973.1 - 3.6 7.6 8.4 3.1 7.8 0.3 3.5 3 0 0 3 3 3 0 MerE protein Metallophos PF00149.28 ETS80974.1 - 1.7e-06 28.7 6.3 7.8e-06 26.5 6.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_3_C PF01915.22 ETS80975.1 - 6.5e-63 212.4 0.0 1.4e-62 211.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS80975.1 - 1.3e-54 185.8 0.0 2e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 ETS80975.1 - 7.2e-25 87.5 0.0 1.3e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 ETS80975.1 - 5.5e-24 84.1 0.1 1.3e-23 82.9 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Cation_efflux PF01545.21 ETS80976.1 - 6e-48 163.2 17.6 4e-47 160.5 17.6 1.9 1 1 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 ETS80976.1 - 0.013 14.7 0.5 0.013 14.7 0.5 2.1 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component PQ-loop PF04193.14 ETS80976.1 - 0.025 14.4 0.2 0.025 14.4 0.2 2.2 3 0 0 3 3 3 0 PQ loop repeat SWIRM-assoc_2 PF16496.5 ETS80977.1 - 0.00034 19.6 0.4 0.00034 19.6 0.4 4.7 4 1 0 5 5 5 1 SWIRM-associated domain at the N-terminal AT_hook PF02178.19 ETS80977.1 - 0.00076 19.1 2.6 1.2 9.3 0.9 3.5 2 0 0 2 2 2 2 AT hook motif PLA2_B PF01735.18 ETS80978.1 - 6e-189 628.5 1.2 7.1e-189 628.3 1.2 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 ETS80978.1 - 0.16 12.2 0.7 0.3 11.3 0.7 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain SopA PF13981.6 ETS80978.1 - 0.24 11.8 0.2 0.71 10.3 0.0 1.8 2 0 0 2 2 2 0 SopA-like central domain DUF1295 PF06966.12 ETS80981.1 - 7.2e-58 195.9 1.2 8.9e-58 195.6 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 ETS80981.1 - 5.7e-06 26.4 0.2 5.7e-06 26.4 0.2 2.8 1 1 2 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 ETS80981.1 - 1.9e-05 25.0 0.1 8.3e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 ETS80981.1 - 0.0038 17.6 3.2 0.0042 17.5 0.1 2.6 2 1 0 2 2 2 1 Phospholipid methyltransferase YaeQ PF07152.12 ETS80983.1 - 0.1 12.2 0.3 0.29 10.7 0.1 1.8 2 0 0 2 2 2 0 YaeQ protein Med8 PF10232.9 ETS80984.1 - 1.3e-31 110.0 3.6 1.9e-31 109.5 3.6 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 RE_Eco47II PF09553.10 ETS80984.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Eco47II restriction endonuclease Allexi_40kDa PF05549.11 ETS80984.1 - 0.22 11.0 1.3 0.34 10.4 1.0 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein TMEM171 PF15471.6 ETS80984.1 - 0.26 10.2 0.2 0.38 9.7 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 COG5 PF10392.9 ETS80984.1 - 0.48 10.6 3.1 0.57 10.4 0.8 2.2 2 1 1 3 3 3 0 Golgi transport complex subunit 5 PYST-C1 PF09690.10 ETS80984.1 - 5.9 6.7 8.5 1.9 8.3 0.4 2.4 2 0 0 2 2 2 0 Plasmodium yoelii subtelomeric region (PYST-C1) Prothymosin PF03247.14 ETS80984.1 - 8.3 6.9 17.0 1.9 9.0 8.2 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family CENP-B_dimeris PF09026.10 ETS80984.1 - 8.7 6.8 15.6 9.5 6.7 4.3 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sulfatase PF00884.23 ETS80985.1 - 5.4e-55 187.0 0.0 6.7e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 ETS80985.1 - 5.5e-21 74.1 0.2 1.4e-20 72.9 0.2 1.7 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 ETS80985.1 - 1.4e-09 38.0 0.0 0.0014 18.3 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 ETS80985.1 - 0.023 14.6 0.0 0.75 9.7 0.0 2.3 1 1 0 1 1 1 0 Domain of unknown function PQ-loop PF04193.14 ETS80986.1 - 3.8e-24 84.2 7.8 9.7e-15 54.1 3.1 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF3431 PF11913.8 ETS80987.1 - 3.5e-70 236.1 0.0 4.8e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Gln-synt_C PF00120.24 ETS80991.1 - 2e-72 244.1 0.0 2.8e-72 243.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 ETS80991.1 - 3.6e-11 43.4 0.0 2.7e-10 40.5 0.0 2.4 2 1 0 2 2 2 1 Amidohydrolase DUF5372 PF17342.2 ETS80991.1 - 0.14 12.6 0.0 0.42 11.0 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5372) RRM_1 PF00076.22 ETS80992.1 - 7e-22 77.0 1.4 3.3e-13 49.2 0.0 3.6 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ETS80992.1 - 4e-06 26.9 0.1 0.00039 20.5 0.1 2.5 2 1 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 ETS80992.1 - 0.025 14.6 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DHquinase_I PF01487.15 ETS80992.1 - 0.088 13.0 0.0 0.18 12.1 0.0 1.7 1 1 0 1 1 1 0 Type I 3-dehydroquinase PRK PF00485.18 ETS80993.1 - 2.9e-07 30.4 0.0 4.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 ETS80993.1 - 0.00016 20.9 0.0 0.00024 20.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 ETS80993.1 - 0.0017 18.9 0.0 0.0068 17.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ETS80993.1 - 0.0022 18.2 0.0 0.0036 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ETS80993.1 - 0.0044 17.2 0.2 0.21 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 ETS80993.1 - 0.0082 15.8 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase Zeta_toxin PF06414.12 ETS80993.1 - 0.0094 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.12 ETS80993.1 - 0.056 13.4 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 ETS80993.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 NTPase Mg_chelatase PF01078.21 ETS80993.1 - 0.17 11.3 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PRELI PF04707.14 ETS80995.1 - 3.8e-41 140.5 0.3 4.5e-41 140.3 0.3 1.0 1 0 0 1 1 1 1 PRELI-like family Pico_P2B PF01552.17 ETS80995.1 - 0.061 13.5 0.2 0.24 11.6 0.0 1.9 1 1 1 2 2 2 0 Picornavirus 2B protein Fringe PF02434.16 ETS80996.1 - 8.9e-05 22.0 2.4 0.00097 18.6 2.4 2.3 1 1 0 1 1 1 1 Fringe-like HRM PF02793.22 ETS80997.1 - 0.012 15.9 0.8 0.018 15.4 0.8 1.4 1 1 0 1 1 1 0 Hormone receptor domain Peptidase_M24 PF00557.24 ETS80998.1 - 7.6e-38 130.3 0.0 9.9e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3323 PF11796.8 ETS80998.1 - 0.039 13.9 0.2 0.063 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) REV PF00424.18 ETS80998.1 - 0.086 12.9 1.4 0.85 9.7 0.1 2.3 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) CPSF100_C PF13299.6 ETS80998.1 - 1.3 9.2 3.9 2.3 8.4 3.9 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal GFO_IDH_MocA PF01408.22 ETS80999.1 - 1.4e-17 64.6 0.0 2.3e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CorA PF01544.18 ETS81000.1 - 3.1e-05 23.4 0.1 5.4e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein HSBP1 PF06825.12 ETS81000.1 - 0.079 12.8 0.1 0.079 12.8 0.1 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF1574 PF07611.11 ETS81000.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) OST3_OST6 PF04756.13 ETS81000.1 - 0.32 10.3 1.1 3.2 7.0 0.3 2.1 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family NPP1 PF05630.11 ETS81001.1 - 1.2e-60 205.0 0.0 1.4e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) FAD_binding_3 PF01494.19 ETS81002.1 - 6.2e-15 55.3 1.7 2.6e-14 53.2 1.7 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS81002.1 - 1.7e-06 27.9 1.0 0.00046 19.9 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS81002.1 - 3.1e-06 27.3 0.2 1e-05 25.7 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS81002.1 - 0.00031 20.1 0.4 0.0041 16.4 0.1 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ETS81002.1 - 0.00086 18.7 0.1 0.049 12.9 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 ETS81002.1 - 0.0015 18.6 0.2 0.58 10.1 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding SE PF08491.10 ETS81002.1 - 0.0029 16.7 0.0 0.041 12.9 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_3 PF13738.6 ETS81002.1 - 0.0094 15.2 0.3 1 8.5 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS81002.1 - 0.017 14.2 1.0 0.029 13.4 0.3 1.7 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 ETS81002.1 - 0.043 12.5 0.1 0.097 11.3 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 ETS81002.1 - 0.082 11.9 0.4 0.39 9.7 0.4 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 ETS81002.1 - 0.1 11.4 1.1 0.22 10.3 0.2 1.8 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.22 ETS81002.1 - 0.1 11.6 0.2 0.15 11.1 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Hist_deacetyl PF00850.19 ETS81002.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Histone deacetylase domain Pyr_redox PF00070.27 ETS81002.1 - 0.14 12.8 0.4 0.42 11.2 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.32 ETS81003.1 - 6.7e-19 67.9 5.5 0.0031 18.3 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS81003.1 - 2.8e-08 34.0 0.0 1.4e-05 25.3 0.0 4.0 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ETS81003.1 - 0.00018 21.0 0.0 0.00032 20.1 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Ge1_WD40 PF16529.5 ETS81003.1 - 0.03 13.3 0.5 0.41 9.6 0.0 2.7 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ETS81003.1 - 0.03 14.2 0.6 6.3 6.6 0.0 2.9 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Tubulin PF00091.25 ETS81005.1 - 1.3e-69 234.4 0.1 1.8e-69 233.9 0.1 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ETS81005.1 - 1.2e-45 154.8 0.3 2.9e-45 153.5 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ETS81005.1 - 9.2e-08 32.4 0.0 2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 ETS81005.1 - 0.11 12.2 0.0 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 Tubulin domain AIM5 PF17050.5 ETS81008.1 - 7.1e-21 74.8 1.0 7.1e-21 74.8 1.0 2.2 3 0 0 3 3 3 1 Altered inheritance of mitochondria 5 EspB PF05802.11 ETS81008.1 - 0.027 14.5 8.5 0.038 14.0 8.5 1.2 1 0 0 1 1 1 0 Enterobacterial EspB protein DUF2884 PF11101.8 ETS81008.1 - 0.27 10.7 2.5 0.93 9.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) YtxH PF12732.7 ETS81008.1 - 1.6 9.4 10.8 13 6.4 0.6 2.8 1 1 1 2 2 2 0 YtxH-like protein Spt5_N PF11942.8 ETS81008.1 - 4.4 8.3 9.2 38 5.3 5.8 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF768 PF05589.11 ETS81008.1 - 5.8 7.0 7.6 1.8 8.6 2.9 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF768) Ribosomal_L17 PF01196.19 ETS81009.1 - 5.5e-33 113.7 0.2 5.5e-33 113.7 0.2 2.1 2 1 0 2 2 2 1 Ribosomal protein L17 DALR_1 PF05746.15 ETS81009.1 - 0.082 13.1 1.6 0.96 9.6 0.1 2.4 2 0 0 2 2 2 0 DALR anticodon binding domain UTP25 PF06862.12 ETS81010.1 - 9.7e-196 651.1 0.3 1.2e-195 650.8 0.3 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 ETS81010.1 - 0.00024 20.9 0.1 0.016 15.0 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase JAB PF01398.21 ETS81011.1 - 1.4e-17 63.7 0.0 3e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 ETS81011.1 - 7.3e-17 61.8 1.1 1e-16 61.3 0.3 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function DUF2526 PF10735.9 ETS81011.1 - 0.091 12.9 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) Cupin_2 PF07883.11 ETS81012.1 - 0.00088 18.9 0.0 0.13 12.0 0.0 2.5 1 1 0 1 1 1 1 Cupin domain Peptidase_M23_N PF18421.1 ETS81012.1 - 0.12 12.3 0.0 0.45 10.5 0.0 2.0 2 0 0 2 2 2 0 Peptidase family M23 N-terminal domain CFEM PF05730.11 ETS81014.1 - 4.8e-13 49.0 12.5 5.9e-13 48.7 12.5 1.1 1 0 0 1 1 1 1 CFEM domain Lipase_3 PF01764.25 ETS81015.1 - 9.3e-35 119.6 0.0 1.3e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 ETS81015.1 - 3.8e-05 23.1 0.0 6.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS81015.1 - 4.3e-05 24.2 0.0 6.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 ETS81015.1 - 0.00017 21.3 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 ETS81015.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein MFS_1 PF07690.16 ETS81016.1 - 6.3e-40 137.2 30.2 6.3e-40 137.2 30.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS81016.1 - 4.3e-11 42.3 8.8 4.3e-11 42.3 8.8 3.1 2 2 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 ETS81016.1 - 1.5e-05 23.6 3.7 2.3e-05 23.1 3.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_61 PF03443.14 ETS81017.1 - 1.3e-43 149.3 0.0 1.7e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 ETS81017.1 - 0.038 14.2 1.7 1.9 8.8 0.0 3.0 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase MG2 PF01835.19 ETS81017.1 - 0.082 13.4 0.0 0.2 12.1 0.0 1.8 1 1 0 1 1 1 0 MG2 domain DUF1118 PF06549.12 ETS81018.1 - 0.071 13.4 1.3 0.097 13.0 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) APOBEC4 PF18775.1 ETS81018.1 - 0.17 12.0 0.2 0.27 11.4 0.2 1.3 1 0 0 1 1 1 0 APOBEC4 SNAD4 PF18750.1 ETS81018.1 - 0.19 11.8 0.8 0.36 11.0 0.8 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Acetyltransf_1 PF00583.25 ETS81019.1 - 1.4e-09 38.2 0.0 2.5e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS81019.1 - 4.3e-08 33.2 0.0 8.1e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS81019.1 - 4.4e-06 27.0 0.0 8.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS81019.1 - 0.00016 21.6 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ETS81019.1 - 0.00094 19.3 0.0 0.0018 18.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ETS81019.1 - 0.016 15.3 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase SUZ PF12752.7 ETS81021.1 - 2.7e-15 56.8 3.1 2.7e-15 56.8 3.1 4.2 3 1 0 3 3 3 1 SUZ domain R3H PF01424.22 ETS81021.1 - 5.5e-08 32.7 0.0 2e-07 30.9 0.1 1.9 2 0 0 2 2 2 1 R3H domain cwf18 PF08315.12 ETS81022.1 - 5.7e-46 156.5 5.7 5.7e-46 156.5 5.7 1.8 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor PPR_2 PF13041.6 ETS81023.1 - 1.1e-21 76.7 0.0 5.4e-07 29.7 0.0 5.6 7 0 0 7 7 7 3 PPR repeat family PPR PF01535.20 ETS81023.1 - 1.2e-12 47.2 0.0 0.0048 17.1 0.0 4.8 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 ETS81023.1 - 3e-12 46.4 0.0 1.5e-05 25.0 0.0 4.2 2 2 2 4 4 4 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 ETS81023.1 - 3.9e-10 39.2 0.0 0.00012 21.7 0.0 4.6 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 ETS81023.1 - 1.4e-06 27.8 0.0 0.018 14.4 0.0 2.6 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP Fungal_trans PF04082.18 ETS81024.1 - 3.6e-15 55.7 0.3 7.5e-15 54.7 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS81024.1 - 1.3e-08 34.8 9.0 2.7e-08 33.8 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.26 ETS81025.1 - 3.9e-12 46.3 0.6 6.9e-12 45.5 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS81025.1 - 1.9e-06 27.7 0.1 9e-05 22.3 0.0 2.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NmrA PF05368.13 ETS81025.1 - 0.00014 21.5 0.2 0.00024 20.8 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 ETS81025.1 - 0.00023 20.7 0.4 0.00044 19.8 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS81025.1 - 0.016 14.7 0.5 0.028 14.0 0.5 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase AlaDh_PNT_C PF01262.21 ETS81025.1 - 0.2 11.0 7.7 0.13 11.6 5.6 1.6 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Hexapep_2 PF14602.6 ETS81026.1 - 1.9e-13 49.9 12.1 6.1e-08 32.3 1.6 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 ETS81026.1 - 4.6e-13 48.3 10.0 2.2e-06 27.1 1.1 3.5 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 ETS81026.1 - 1.4e-11 44.4 0.1 4.1e-11 42.9 0.1 1.8 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.18 ETS81026.1 - 1e-09 38.3 8.0 2.1e-09 37.3 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.6 ETS81027.1 - 1.3e-27 96.9 0.0 2.2e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS81027.1 - 2.4e-15 56.9 0.0 4.1e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2397 PF09660.10 ETS81028.1 - 0.054 12.4 0.1 0.65 8.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2397) Aldo_ket_red PF00248.21 ETS81029.1 - 5.9e-46 157.0 0.0 1.7e-45 155.5 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family LRRNT_2 PF08263.12 ETS81030.1 - 0.12 12.7 0.6 0.12 12.7 0.6 2.8 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain Asparaginase_2 PF01112.18 ETS81030.1 - 0.18 10.8 7.4 0.2 10.6 7.4 1.1 1 0 0 1 1 1 0 Asparaginase Pkinase PF00069.25 ETS81031.1 - 2.6e-27 95.8 0.0 3.1e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS81031.1 - 1.7e-14 53.7 0.0 2.2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ETS81031.1 - 4.5e-07 29.0 0.0 6.2e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Peptidase_M44 PF03410.13 ETS81031.1 - 0.17 10.4 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase from vaccinia pox EMP24_GP25L PF01105.24 ETS81032.1 - 1.8e-51 174.7 0.0 2e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SANT_DAMP1_like PF16282.5 ETS81033.1 - 1.2e-29 102.3 1.2 2.4e-29 101.3 1.2 1.6 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 ETS81033.1 - 0.071 13.4 0.0 0.31 11.3 0.0 2.1 1 1 0 1 1 1 0 Myb-like DNA-binding domain Secretin_N PF03958.17 ETS81033.1 - 0.24 11.8 4.8 1.6 9.2 0.0 3.2 3 0 0 3 3 3 0 Bacterial type II/III secretion system short domain Pox_LP_H2 PF03356.15 ETS81036.1 - 0.091 12.6 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Viral late protein H2 Beta-lactamase PF00144.24 ETS81037.1 - 1e-63 215.6 0.0 1.2e-63 215.4 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase S4 PF01479.25 ETS81037.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 S4 domain LCM PF04072.14 ETS81038.1 - 2.6e-20 73.1 0.0 5.2e-20 72.2 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase AIM24 PF01987.17 ETS81039.1 - 5.6e-48 163.4 0.1 6.9e-48 163.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Med1 PF10744.9 ETS81040.1 - 3.3e-99 332.8 0.0 4e-99 332.5 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 BTB PF00651.31 ETS81042.1 - 0.00015 21.9 0.1 0.005 17.0 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain SCRG1 PF15224.6 ETS81042.1 - 0.049 13.8 8.3 0.32 11.1 0.1 2.6 2 0 0 2 2 2 0 Scrapie-responsive protein 1 BTB PF00651.31 ETS81043.1 - 0.019 15.2 0.0 0.057 13.7 0.0 1.8 1 0 0 1 1 1 0 BTB/POZ domain Imm3 PF14425.6 ETS81043.1 - 0.066 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Immunity protein Imm3 MRC1 PF09444.10 ETS81045.1 - 1e-41 142.9 18.8 1e-41 142.9 18.8 8.1 5 2 1 7 7 7 1 MRC1-like domain TFIIA PF03153.13 ETS81045.1 - 0.0032 17.5 30.6 0.0032 17.5 30.6 5.0 3 1 1 5 5 5 2 Transcription factor IIA, alpha/beta subunit SAGA-Tad1 PF12767.7 ETS81046.1 - 9.9e-66 221.8 0.0 1.3e-65 221.4 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit GCP_C_terminal PF04130.13 ETS81048.1 - 1.5e-97 326.8 0.1 2.4e-97 326.2 0.1 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 ETS81048.1 - 4.5e-87 292.5 0.0 7.9e-87 291.7 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Pkinase PF00069.25 ETS81049.1 - 2.3e-45 155.0 0.0 2.1e-43 148.6 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS81049.1 - 5.3e-24 84.9 0.0 1.7e-23 83.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase MFS_1 PF07690.16 ETS81050.1 - 3e-39 135.0 43.8 3e-39 135.0 43.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS81050.1 - 0.00012 21.0 31.2 0.00063 18.7 31.1 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.18 ETS81051.1 - 1e-12 47.7 0.0 2e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS81051.1 - 3.2e-06 27.1 10.2 7.2e-06 26.0 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBM_4_9 PF02018.17 ETS81052.1 - 6.2e-05 23.3 0.3 6.2e-05 23.3 0.3 2.0 2 1 0 2 2 2 1 Carbohydrate binding domain DUF642 PF04862.12 ETS81052.1 - 0.092 12.5 1.0 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF642) adh_short PF00106.25 ETS81053.1 - 1e-31 109.9 0.0 2.7e-31 108.6 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS81053.1 - 1.2e-17 64.3 0.0 1.5e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS81053.1 - 1.3e-09 38.3 0.0 1.7e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS81053.1 - 0.0057 16.2 0.1 0.0089 15.5 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 ETS81053.1 - 0.011 15.5 0.1 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.15 ETS81053.1 - 0.032 13.4 0.4 0.047 12.8 0.4 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ETS81053.1 - 0.056 12.8 0.1 0.1 12.0 0.1 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 ETS81053.1 - 0.18 12.1 0.6 0.31 11.3 0.3 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF2231 PF09990.9 ETS81055.1 - 0.0052 17.2 2.0 0.018 15.5 1.9 1.9 1 1 0 1 1 1 1 Predicted membrane protein (DUF2231) Type_III_YscG PF09477.10 ETS81055.1 - 0.076 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) HsbA PF12296.8 ETS81056.1 - 3.1e-12 47.0 3.8 4.9e-12 46.3 3.8 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Tyrosinase PF00264.20 ETS81057.1 - 3.5e-45 155.0 0.0 4.9e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase HMG_box_2 PF09011.10 ETS81057.1 - 0.047 14.3 0.1 0.084 13.5 0.1 1.4 1 0 0 1 1 1 0 HMG-box domain FAD_binding_4 PF01565.23 ETS81059.1 - 1.1e-21 77.0 2.8 2.3e-21 76.0 2.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS81059.1 - 8.7e-11 41.8 0.2 2.2e-10 40.5 0.1 1.8 2 0 0 2 2 2 1 Berberine and berberine like F-box PF00646.33 ETS81060.1 - 5.4e-05 23.0 0.0 0.00014 21.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ETS81060.1 - 0.00033 20.5 0.0 0.0009 19.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ETS81060.1 - 0.0012 18.7 0.0 0.0032 17.3 0.0 1.9 1 0 0 1 1 1 1 F-box Bys1 PF04681.12 ETS81061.1 - 0.11 12.5 0.4 0.28 11.1 0.1 1.7 1 1 1 2 2 2 0 Blastomyces yeast-phase-specific protein FA_hydroxylase PF04116.13 ETS81061.1 - 0.15 12.4 2.1 0.22 11.9 2.1 1.3 1 0 0 1 1 1 0 Fatty acid hydroxylase superfamily SelK_SelG PF10961.8 ETS81061.1 - 3.2 8.4 7.3 1 10.0 4.6 1.6 2 0 0 2 2 2 0 Selenoprotein SelK_SelG Y_phosphatase3 PF13350.6 ETS81062.1 - 8.5e-54 183.0 0.0 9.9e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ETS81062.1 - 0.036 13.6 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 ETS81062.1 - 0.056 13.0 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Amidohydro_3 PF07969.11 ETS81063.1 - 9.2e-64 216.6 0.0 1.1e-63 216.3 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ETS81063.1 - 7.6e-06 25.5 0.0 3.5e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase family FSH1 PF03959.13 ETS81065.1 - 4.4e-25 88.6 0.0 7.2e-25 87.9 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ketoacyl-synt PF00109.26 ETS81066.1 - 8.1e-73 245.1 0.0 2.3e-72 243.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ETS81066.1 - 1.9e-64 216.9 3.3 3.3e-64 216.1 2.2 2.1 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 ETS81066.1 - 3.7e-61 207.4 0.0 6.5e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 ETS81066.1 - 1.2e-58 198.8 0.1 2.3e-58 197.8 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 ETS81066.1 - 8.2e-40 135.5 0.4 2.5e-39 134.0 0.1 2.1 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 ETS81066.1 - 8.1e-20 72.2 0.1 1.1e-18 68.6 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 ETS81066.1 - 1.2e-18 67.6 0.1 5e-18 65.6 0.1 2.2 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 ETS81066.1 - 6.7e-16 58.5 0.2 3e-15 56.4 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 ETS81066.1 - 1.4e-14 54.0 2.5 1.4e-14 54.0 2.5 3.6 4 0 0 4 4 4 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS81066.1 - 3.4e-09 36.6 1.6 9.6e-09 35.1 1.1 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 ETS81066.1 - 3.3e-08 33.8 0.9 1.5e-07 31.6 0.1 2.6 3 0 0 3 3 2 1 Phosphopantetheine attachment site ADH_N PF08240.12 ETS81066.1 - 3.2e-07 30.2 0.0 1.1e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.10 ETS81066.1 - 0.00015 21.5 0.3 0.0013 18.6 0.3 2.4 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Polysacc_synt_2 PF02719.15 ETS81066.1 - 0.0011 18.1 0.3 0.0021 17.2 0.3 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Thiolase_N PF00108.23 ETS81066.1 - 0.0023 17.3 0.1 0.0023 17.3 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Zn_clus PF00172.18 ETS81067.1 - 2.5e-08 33.9 16.6 4.2e-08 33.2 16.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 ETS81067.1 - 2.6 7.9 10.8 2.3 8.0 7.4 2.2 1 1 1 2 2 2 0 Integrin plexin domain adh_short PF00106.25 ETS81068.1 - 1.8e-30 105.8 0.0 2.6e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS81068.1 - 6.3e-23 81.5 0.0 7.1e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS81068.1 - 5e-07 29.8 0.0 6.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS81068.1 - 3.2e-06 26.8 0.0 5.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS81068.1 - 0.00024 21.1 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ETS81068.1 - 0.003 17.0 0.0 0.0074 15.7 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ETS81068.1 - 0.0057 16.2 0.1 0.015 14.8 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.6 ETS81069.1 - 1e-24 87.4 0.6 3.3e-16 59.6 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS81069.1 - 2.4e-18 66.3 0.2 1e-10 41.4 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 ETS81069.1 - 0.0011 18.9 0.3 0.0018 18.2 0.3 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 ETS81069.1 - 0.0037 16.6 0.0 0.0066 15.8 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 ETS81069.1 - 0.019 14.9 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PCMT PF01135.19 ETS81069.1 - 0.062 13.0 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Eno-Rase_NADH_b PF12242.8 ETS81069.1 - 0.077 12.8 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SNF2_N PF00176.23 ETS81070.1 - 4.7e-75 252.5 0.9 1.6e-74 250.8 0.1 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 ETS81070.1 - 2.7e-40 137.0 2.4 2.7e-40 137.0 2.4 2.7 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 ETS81070.1 - 2.4e-35 121.7 7.2 2.4e-35 121.7 7.2 3.5 4 0 0 4 4 4 1 HAND Helicase_C PF00271.31 ETS81070.1 - 9.5e-19 67.8 0.2 5e-18 65.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS81070.1 - 7.5e-12 45.6 0.6 1.4e-10 41.5 0.0 3.2 3 2 1 4 4 4 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 ETS81070.1 - 7.9e-06 26.0 0.8 0.00016 21.8 0.1 2.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain HDA2-3 PF11496.8 ETS81070.1 - 5.1e-05 22.6 0.0 0.00023 20.5 0.0 2.1 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF1086 PF06461.11 ETS81070.1 - 6.3e-05 22.8 0.2 6.3e-05 22.8 0.2 1.8 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1086) SWI2_SNF2 PF18766.1 ETS81070.1 - 0.00042 20.1 0.1 0.0018 18.0 0.0 2.1 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 ETS81070.1 - 0.00045 20.0 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.6 ETS81070.1 - 0.037 14.1 0.3 0.2 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain DEAD_2 PF06733.15 ETS81070.1 - 0.065 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 DUF4588 PF15251.6 ETS81071.1 - 1e-08 35.3 0.1 1.6e-08 34.6 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) tRNA_SAD PF07973.14 ETS81072.1 - 2.1e-06 27.7 0.4 3.7e-06 26.9 0.4 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 ETS81072.1 - 3.1e-05 22.7 0.1 8.9e-05 21.2 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (A) PRP3 PF08572.10 ETS81072.1 - 0.21 11.3 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) Ank_2 PF12796.7 ETS81073.1 - 5.1e-42 142.3 0.3 2.8e-12 47.1 0.0 5.6 1 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS81073.1 - 3.8e-30 103.9 0.2 2.9e-07 30.9 0.0 7.3 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS81073.1 - 2.4e-27 94.6 0.1 9.1e-08 32.2 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 ETS81073.1 - 3.7e-25 87.2 0.1 1.8e-05 24.9 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 ETS81073.1 - 2.9e-21 73.3 0.0 0.0013 19.1 0.0 8.8 8 0 0 8 8 8 3 Ankyrin repeat NACHT PF05729.12 ETS81073.1 - 3.7e-09 36.7 0.0 1e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 ETS81073.1 - 3.3e-05 23.3 1.5 0.021 14.1 0.1 2.4 1 1 0 2 2 2 2 KAP family P-loop domain AAA_22 PF13401.6 ETS81073.1 - 0.00011 22.5 0.1 0.0012 19.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 ETS81073.1 - 0.0019 18.6 0.1 0.022 15.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 ETS81073.1 - 0.0036 17.7 0.0 0.01 16.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 ETS81073.1 - 0.0042 17.6 0.0 0.018 15.5 0.0 2.1 2 0 0 2 2 1 1 ABC transporter Ploopntkinase3 PF18751.1 ETS81073.1 - 0.0052 16.7 0.1 0.13 12.2 0.0 2.4 3 0 0 3 3 2 1 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 ETS81073.1 - 0.021 14.1 0.0 0.27 10.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 ETS81073.1 - 0.029 14.9 0.0 0.079 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ETS81073.1 - 0.051 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AFG1_ATPase PF03969.16 ETS81073.1 - 0.065 12.1 0.0 0.2 10.5 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase P16-Arc PF04699.14 ETS81073.1 - 0.073 13.6 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) ATPase PF06745.13 ETS81073.1 - 0.084 12.2 0.0 0.22 10.8 0.0 1.7 1 1 0 1 1 1 0 KaiC AAA_30 PF13604.6 ETS81073.1 - 0.087 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ETS81073.1 - 0.12 12.4 0.0 0.57 10.3 0.0 2.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase PNP_UDP_1 PF01048.20 ETS81074.1 - 2.6e-12 46.5 0.0 8.3e-12 44.9 0.0 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Acyl_transf_3 PF01757.22 ETS81075.1 - 2.8e-45 154.9 36.1 4.1e-45 154.3 36.1 1.3 1 0 0 1 1 1 1 Acyltransferase family Acyl-CoA_dh_1 PF00441.24 ETS81076.1 - 8.5e-31 107.2 1.2 1.3e-30 106.6 1.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ETS81076.1 - 9.3e-25 86.7 0.3 1.5e-24 86.0 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ETS81076.1 - 4.8e-19 69.1 0.0 1.1e-18 67.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ETS81076.1 - 0.0096 16.2 0.1 0.021 15.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain p450 PF00067.22 ETS81079.1 - 1.7e-63 215.0 0.0 2.5e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 ETS81080.1 - 0.0015 17.4 0.1 0.0059 15.5 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 ETS81081.1 - 5.1e-07 28.8 0.2 6.1e-06 25.3 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain FAD_binding_1 PF00667.20 ETS81082.1 - 1.3e-48 165.5 0.0 1.9e-48 164.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ETS81082.1 - 1.1e-30 106.8 0.0 2.7e-30 105.4 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ETS81082.1 - 7.1e-20 71.7 0.0 5.3e-19 68.9 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Chitin_synth_1 PF01644.17 ETS81083.1 - 1.6e-73 246.1 0.1 2.4e-73 245.5 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ETS81083.1 - 8.4e-30 102.5 0.0 1.5e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ETS81083.1 - 3.7e-23 81.9 1.9 2.1e-17 63.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ETS81083.1 - 2.8e-05 24.1 9.2 2.8e-05 24.1 9.2 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ETS81083.1 - 0.038 13.9 0.0 0.083 12.8 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DUF2457 PF10446.9 ETS81084.1 - 0.4 9.8 18.5 0.42 9.7 18.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.11 ETS81084.1 - 0.64 10.0 7.7 0.71 9.9 7.7 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 ETS81084.1 - 0.76 9.4 7.5 1 9.0 7.5 1.3 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 ETS81084.1 - 1 7.5 14.5 1 7.5 14.5 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 ETS81084.1 - 1.5 8.0 6.0 1.4 8.1 6.0 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pns11_12 PF17464.2 ETS81084.1 - 1.8 8.2 7.4 2.1 8.0 7.4 1.0 1 0 0 1 1 1 0 Non-structural protein 11 and 12 CDC45 PF02724.14 ETS81084.1 - 1.9 6.7 13.1 1.9 6.7 13.1 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 ETS81084.1 - 2 7.7 18.4 2.1 7.6 18.4 1.0 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 ETS81084.1 - 2.2 6.2 21.9 2.4 6.2 21.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2722 PF10846.8 ETS81084.1 - 2.6 6.9 8.2 2.7 6.9 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4637 PF15470.6 ETS81084.1 - 3.8 7.2 8.0 4.2 7.1 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) SDA1 PF05285.12 ETS81084.1 - 4.4 6.6 15.4 4.5 6.6 15.4 1.0 1 0 0 1 1 1 0 SDA1 Rhabdo_ncap PF00945.18 ETS81084.1 - 4.6 6.0 7.8 4.6 6.0 7.8 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein GMC_oxred_N PF00732.19 ETS81086.1 - 6.6e-65 219.4 0.0 9e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS81086.1 - 8.4e-34 117.2 0.0 1.4e-33 116.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS81086.1 - 1.7e-07 30.7 0.1 0.0025 17.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 ETS81086.1 - 8.6e-06 25.6 0.1 3.4e-05 23.6 0.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS81086.1 - 1.5e-05 25.1 0.0 5.2e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ETS81086.1 - 9e-05 21.7 0.1 0.00015 21.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ETS81086.1 - 0.00063 19.1 0.0 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS81086.1 - 0.0017 17.1 0.1 0.045 12.5 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 ETS81086.1 - 0.002 17.4 0.1 0.0054 16.0 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 ETS81086.1 - 0.0038 16.5 0.0 0.96 8.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Sec1 PF00995.23 ETS81087.1 - 8.9e-124 414.8 0.0 1.1e-123 414.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family FANCI_HD2 PF14680.6 ETS81087.1 - 0.049 12.9 0.1 0.094 12.0 0.1 1.4 1 0 0 1 1 1 0 FANCI helical domain 2 zf-CCCH_4 PF18044.1 ETS81088.1 - 2.5e-06 27.2 1.5 4e-06 26.5 1.5 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ETS81088.1 - 4.2e-06 26.6 4.7 7.2e-06 25.9 4.7 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 ETS81088.1 - 0.00015 21.6 1.6 0.00028 20.7 1.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 ETS81088.1 - 0.0025 18.0 0.1 0.0085 16.3 0.1 2.0 1 0 0 1 1 1 1 Zinc-finger containing family Torus PF16131.5 ETS81088.1 - 0.0062 17.2 1.7 0.0062 17.2 1.7 2.8 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 ETS81088.1 - 0.013 15.9 1.8 0.023 15.2 1.8 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF16 PF01519.16 ETS81088.1 - 10 6.7 6.9 0.62 10.6 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 2_5_RNA_ligase2 PF13563.6 ETS81089.1 - 1.1e-11 44.9 0.0 1.7e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Ank_2 PF12796.7 ETS81090.1 - 7.4e-41 138.6 2.9 4.3e-11 43.2 0.1 5.9 3 3 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS81090.1 - 4.4e-31 106.8 5.7 2.5e-06 27.9 0.1 7.7 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS81090.1 - 7.7e-28 93.5 0.7 0.00016 21.9 0.1 10.3 11 0 0 11 11 11 5 Ankyrin repeat Ank PF00023.30 ETS81090.1 - 2.3e-23 81.5 0.4 1.8e-06 28.2 0.1 9.2 9 1 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 ETS81090.1 - 4.8e-21 74.5 9.2 1.2e-05 25.5 0.0 8.5 6 3 2 8 8 8 5 Ankyrin repeats (many copies) CorA PF01544.18 ETS81091.1 - 1.1e-07 31.4 1.9 2.6e-07 30.2 1.8 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PMC2NT PF08066.12 ETS81091.1 - 0.052 14.2 1.2 0.2 12.3 1.2 2.0 1 0 0 1 1 1 0 PMC2NT (NUC016) domain NADH_dehy_S2_C PF06444.11 ETS81091.1 - 0.073 13.6 0.2 0.24 11.9 0.2 1.9 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus Biotin_carb_N PF00289.22 ETS81092.1 - 2.8e-34 118.0 0.0 4e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain CPSase_L_D2 PF02786.17 ETS81092.1 - 1.5e-08 34.5 0.1 2.8e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Aminotran_3 PF00202.21 ETS81093.1 - 1.1e-79 268.0 0.0 1.3e-79 267.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF166 PF02593.14 ETS81093.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function Fungal_trans_2 PF11951.8 ETS81094.1 - 2.5e-46 158.3 0.5 3e-46 158.0 0.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Apolipoprotein PF01442.18 ETS81094.1 - 0.076 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Zn_clus PF00172.18 ETS81095.1 - 0.0008 19.5 6.8 0.0013 18.8 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SGS PF05002.15 ETS81095.1 - 0.078 13.1 0.2 0.13 12.4 0.2 1.3 1 0 0 1 1 1 0 SGS domain DUF3144 PF11342.8 ETS81095.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) Cupin_7 PF12973.7 ETS81096.1 - 1.7e-12 47.1 0.1 2.7e-12 46.4 0.1 1.3 1 0 0 1 1 1 1 ChrR Cupin-like domain Chitin_bind_4 PF00379.23 ETS81096.1 - 0.03 14.9 0.0 0.12 13.0 0.0 2.0 2 0 0 2 2 2 0 Insect cuticle protein Cupin_2 PF07883.11 ETS81096.1 - 0.056 13.2 1.2 0.1 12.3 1.2 1.5 1 0 0 1 1 1 0 Cupin domain LamB_YcsF PF03746.16 ETS81097.1 - 6.3e-22 78.4 0.0 7.2e-22 78.2 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family AA_permease PF00324.21 ETS81098.1 - 2.4e-95 319.9 36.7 2.9e-95 319.6 36.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS81098.1 - 3.5e-21 75.5 36.4 4.3e-21 75.2 36.4 1.0 1 0 0 1 1 1 1 Amino acid permease zf-CCHC_2 PF13696.6 ETS81098.1 - 1.3 8.9 3.8 3.5 7.5 0.8 2.3 2 0 0 2 2 2 0 Zinc knuckle Sacchrp_dh_NADP PF03435.18 ETS81099.1 - 2.9e-16 59.9 0.0 1.7e-15 57.5 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 ETS81099.1 - 1.7e-06 28.1 0.0 2.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS81099.1 - 0.013 15.0 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF4448 PF14610.6 ETS81100.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Sulfatase PF00884.23 ETS81101.1 - 6.4e-66 222.8 0.1 8.9e-66 222.4 0.1 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 ETS81101.1 - 1.1e-18 67.4 1.1 2e-17 63.3 1.1 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 ETS81101.1 - 7.1e-09 35.7 0.1 3.6e-08 33.4 0.1 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 ETS81101.1 - 0.038 12.6 0.1 0.069 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) FSA_C PF10479.9 ETS81102.1 - 2.9 5.9 11.6 3.7 5.6 11.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Zn_clus PF00172.18 ETS81103.1 - 5.9e-10 39.1 6.3 1e-09 38.3 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS81103.1 - 1.2e-07 31.0 0.0 2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 ETS81104.1 - 1.6e-22 80.0 45.6 1.6e-22 80.0 45.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.19 ETS81105.1 - 2e-20 73.4 0.0 2.6e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS81105.1 - 6.2e-10 39.2 1.4 2e-05 24.4 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS81105.1 - 1.4e-07 31.0 1.4 0.004 16.4 0.0 2.4 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS81105.1 - 8.2e-06 24.8 0.3 0.0074 15.0 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 ETS81105.1 - 0.0002 20.7 0.1 0.0027 17.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS81105.1 - 0.00083 19.5 0.1 0.0023 18.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ETS81105.1 - 0.0014 19.2 0.1 1.2 9.8 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS81105.1 - 0.0041 16.2 0.2 0.053 12.6 0.1 2.4 3 0 0 3 3 3 1 FAD binding domain Yae1_N PF09811.9 ETS81105.1 - 0.038 13.7 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Essential protein Yae1, N terminal SE PF08491.10 ETS81105.1 - 0.048 12.7 0.0 0.18 10.8 0.0 1.9 1 1 0 1 1 1 0 Squalene epoxidase Lycopene_cycl PF05834.12 ETS81105.1 - 0.05 12.7 0.8 7.8 5.4 0.0 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein 2OG-FeII_Oxy PF03171.20 ETS81106.1 - 3.2e-15 56.5 0.0 5.5e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ETS81106.1 - 1.3e-10 42.1 0.0 2.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Polyketide_cyc2 PF10604.9 ETS81108.1 - 4.9e-06 26.9 0.0 7.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ETS81108.1 - 0.0042 17.3 0.0 0.0058 16.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport PPTA PF01239.22 ETS81108.1 - 0.041 13.6 0.2 0.076 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat p450 PF00067.22 ETS81109.1 - 1.7e-54 185.3 0.0 8.3e-54 183.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.26 ETS81110.1 - 4.2e-06 26.9 4.0 0.0003 21.1 0.3 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ETS81110.1 - 3.1e-05 23.8 0.8 4.8e-05 23.2 0.1 1.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ETS81110.1 - 8.4e-05 23.1 3.0 0.004 17.9 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 ETS81110.1 - 0.0038 17.5 0.0 0.0081 16.4 0.0 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF4451 PF14616.6 ETS81110.1 - 0.042 14.0 0.1 0.21 11.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) Zn-ribbon_8 PF09723.10 ETS81110.1 - 0.11 12.7 0.0 0.34 11.0 0.0 1.9 1 0 0 1 1 1 0 Zinc ribbon domain Cep57_CLD_2 PF14197.6 ETS81110.1 - 0.36 11.0 4.0 1.3 9.1 4.0 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 zf-H2C2_2 PF13465.6 ETS81110.1 - 0.54 10.8 9.3 1.4 9.4 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger double domain PRELI PF04707.14 ETS81111.1 - 1.9e-20 73.2 0.0 1.7e-18 66.9 0.0 2.1 2 0 0 2 2 2 2 PRELI-like family RNase_H PF00075.24 ETS81112.1 - 7.8e-13 48.8 0.0 1.4e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 RNase H NTP_transf_8 PF12281.8 ETS81112.1 - 0.029 14.4 0.1 5.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Nucleotidyltransferase Peptidase_S10 PF00450.22 ETS81114.1 - 4.3e-82 276.7 0.0 5.6e-82 276.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase PCRF PF03462.18 ETS81115.1 - 1.7e-46 158.6 1.2 2.6e-46 157.9 0.0 1.9 2 1 1 3 3 3 1 PCRF domain RF-1 PF00472.20 ETS81115.1 - 1.3e-34 118.6 3.1 4.5e-34 116.9 3.1 1.9 1 0 0 1 1 1 1 RF-1 domain Baculo_PEP_C PF04513.12 ETS81115.1 - 1.4 9.0 3.9 4.1 7.5 0.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2630 PF10944.8 ETS81115.1 - 7.4 7.1 10.5 0.99 9.9 1.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2630) DJ-1_PfpI PF01965.24 ETS81116.1 - 1.2e-05 25.1 0.0 0.12 12.2 0.0 2.4 1 1 1 2 2 2 2 DJ-1/PfpI family LcrR PF09621.10 ETS81116.1 - 0.17 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) adh_short PF00106.25 ETS81117.1 - 9.6e-30 103.5 0.4 2.2e-29 102.3 0.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS81117.1 - 2e-19 70.1 3.0 7.4e-19 68.2 3.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 ETS81117.1 - 2.9e-08 33.8 0.1 6.2e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS81117.1 - 5.4e-07 29.4 0.0 9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family DUF1776 PF08643.10 ETS81117.1 - 0.00022 20.7 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.17 ETS81117.1 - 0.00039 20.9 0.0 0.00087 19.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ETS81117.1 - 0.00043 20.5 0.0 0.00077 19.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DFP PF04127.15 ETS81117.1 - 0.0025 17.7 0.2 0.0053 16.6 0.2 1.5 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.21 ETS81117.1 - 0.0097 15.4 0.0 0.13 11.7 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 ETS81117.1 - 0.015 14.9 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.9 ETS81117.1 - 0.019 14.9 0.8 0.038 13.8 0.2 1.9 2 0 0 2 2 2 0 Rossmann-like domain TrkA_N PF02254.18 ETS81117.1 - 0.027 14.7 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Caskin-tail PF16632.5 ETS81117.1 - 0.057 13.8 0.5 0.27 11.7 0.2 2.3 3 0 0 3 3 2 0 C-terminal region of Caskin 3HCDH_N PF02737.18 ETS81117.1 - 0.092 12.6 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M28 PF04389.17 ETS81119.1 - 6.5e-31 107.6 0.1 1e-30 106.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 F-box-like PF12937.7 ETS81120.1 - 0.00031 20.6 0.3 0.008 16.0 0.0 2.5 2 0 0 2 2 2 1 F-box-like HET PF06985.11 ETS81122.1 - 2.1e-28 99.5 2.4 5.7e-28 98.1 2.4 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CwfJ_C_1 PF04677.15 ETS81122.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 MFS_1 PF07690.16 ETS81123.1 - 1.2e-16 60.6 13.5 1.2e-16 60.6 13.5 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS81123.1 - 1.2e-09 37.6 0.6 1.2e-09 37.6 0.6 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS81124.1 - 2.1e-35 122.3 4.7 2.1e-35 122.3 4.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS81124.1 - 0.00051 19.0 7.1 0.00051 19.0 7.1 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Ank_2 PF12796.7 ETS81125.1 - 5.8e-15 55.6 3.8 7.3e-06 26.5 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS81125.1 - 1.1e-12 48.2 0.3 0.0072 16.9 0.1 5.0 3 1 2 5 5 4 3 Ankyrin repeats (many copies) Ank PF00023.30 ETS81125.1 - 8e-09 35.6 4.4 0.0011 19.4 0.2 5.4 6 0 0 6 6 5 2 Ankyrin repeat NACHT PF05729.12 ETS81125.1 - 1.1e-08 35.2 0.0 2.5e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 ETS81125.1 - 1.5e-07 31.5 3.6 0.0017 18.6 0.2 3.5 2 1 3 5 5 4 4 Ankyrin repeats (many copies) AAA_22 PF13401.6 ETS81125.1 - 5.4e-07 30.0 0.0 2.4e-06 27.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS81125.1 - 6.8e-07 29.8 0.0 2.5e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Ank_3 PF13606.6 ETS81125.1 - 0.0002 21.6 0.9 2.3 9.1 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat NB-ARC PF00931.22 ETS81125.1 - 0.0026 17.0 0.0 0.0047 16.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 ETS81125.1 - 0.0037 17.7 0.0 0.017 15.5 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 ETS81125.1 - 0.042 13.8 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 ETS81125.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NTPase Hydrolase_4 PF12146.8 ETS81125.1 - 0.064 12.5 0.0 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS81125.1 - 0.065 13.8 0.1 0.36 11.4 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF676 PF05057.14 ETS81125.1 - 0.081 12.4 0.0 0.98 8.9 0.0 2.3 2 0 0 2 2 2 0 Putative serine esterase (DUF676) RNA_helicase PF00910.22 ETS81125.1 - 0.15 12.4 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 ETS81125.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 ETS81125.1 - 0.31 10.2 2.2 1.9 7.6 0.1 2.2 1 1 0 2 2 2 0 KAP family P-loop domain CHAT PF12770.7 ETS81126.1 - 3.6e-32 111.9 0.0 7.1e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 ETS81126.1 - 6.2e-28 95.9 13.4 1.4e-05 24.8 0.0 9.4 8 1 1 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.6 ETS81126.1 - 5.6e-09 36.2 3.9 0.054 13.8 0.0 7.1 6 3 2 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 ETS81126.1 - 3.4e-05 23.6 2.3 3.5 8.0 0.0 7.4 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 ETS81126.1 - 0.00029 20.8 2.1 68 4.0 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Peptidase_C50 PF03568.17 ETS81126.1 - 0.00079 18.6 0.1 0.0035 16.5 0.0 2.2 2 0 0 2 2 2 1 Peptidase family C50 TPR_16 PF13432.6 ETS81126.1 - 0.0023 18.5 0.2 0.6 10.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF4404 PF14357.6 ETS81126.1 - 0.0036 17.9 4.4 2.1 9.0 0.1 5.8 6 1 1 7 7 7 1 Domain of unknown function (DUF4404) Peptidase_C25 PF01364.18 ETS81126.1 - 0.046 12.9 0.0 0.1 11.8 0.0 1.5 2 0 0 2 2 2 0 Peptidase family C25 TPR_1 PF00515.28 ETS81126.1 - 2.6 8.0 5.2 6.5 6.7 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Halo_GVPC PF05465.13 ETS81126.1 - 6 7.2 11.1 4.3 7.7 0.5 3.6 4 0 0 4 4 4 0 Halobacterial gas vesicle protein C (GVPC) repeat Peptidase_C14 PF00656.22 ETS81127.1 - 1e-16 61.7 0.0 1.5e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Lactamase_B_2 PF12706.7 ETS81129.1 - 3.8e-30 104.9 0.2 2.5e-29 102.3 0.2 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ETS81129.1 - 8e-10 38.8 0.0 1.6e-09 37.9 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ETS81129.1 - 0.00057 20.0 0.1 0.014 15.4 0.0 2.3 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily adh_short PF00106.25 ETS81130.1 - 1.9e-23 82.9 0.0 2.5e-19 69.5 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS81130.1 - 1.9e-17 63.6 0.1 5.4e-14 52.3 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS81130.1 - 1.9e-06 27.9 0.1 2.9e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS81130.1 - 0.00024 20.6 0.0 0.0005 19.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS81130.1 - 0.013 15.0 0.0 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 ETS81130.1 - 0.06 13.3 0.2 0.61 10.1 0.1 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Tyrosinase PF00264.20 ETS81132.1 - 1.6e-37 130.0 0.0 2.2e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase SIR2 PF02146.17 ETS81133.1 - 4.8e-34 117.8 0.0 6.2e-33 114.2 0.0 2.1 1 1 0 1 1 1 1 Sir2 family DUF1936 PF09151.10 ETS81133.1 - 0.38 10.7 1.1 2.6 8.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) MARVEL PF01284.23 ETS81134.1 - 0.0038 17.3 6.2 0.0089 16.1 6.3 1.6 1 1 0 1 1 1 1 Membrane-associating domain DUF4231 PF14015.6 ETS81134.1 - 0.027 14.9 0.1 0.21 12.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Flavoprotein PF02441.19 ETS81135.1 - 1.2e-41 142.1 0.1 6.9e-41 139.6 0.1 1.9 1 1 0 1 1 1 1 Flavoprotein Glutaredoxin PF00462.24 ETS81136.1 - 7.1e-15 55.0 0.0 1.2e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin G_glu_transpept PF01019.21 ETS81137.1 - 5.1e-144 480.8 0.0 5.9e-144 480.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF1996 PF09362.10 ETS81138.1 - 1.9e-83 280.0 1.5 2.5e-83 279.7 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Sugar_tr PF00083.24 ETS81139.1 - 1.3e-113 380.3 25.2 1.6e-113 380.0 25.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS81139.1 - 6e-22 78.1 48.9 4.8e-15 55.3 18.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS81139.1 - 5e-10 38.4 11.2 5.4e-06 25.1 4.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.16 ETS81139.1 - 0.0039 16.9 2.3 0.0039 16.9 2.3 3.2 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 DUF3165 PF11364.8 ETS81139.1 - 5.7 7.3 6.3 1e+02 3.3 1.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3165) DUF5058 PF16481.5 ETS81140.1 - 0.057 13.1 1.6 0.068 12.8 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5058) DUF1418 PF07214.12 ETS81140.1 - 0.44 10.4 2.5 0.46 10.4 0.3 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) 4HBT_2 PF13279.6 ETS81141.1 - 8.8e-07 29.4 0.0 1.3e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily CFEM PF05730.11 ETS81142.1 - 4.6e-12 45.9 13.5 7.6e-12 45.2 13.5 1.4 1 0 0 1 1 1 1 CFEM domain Sporozoite_P67 PF05642.11 ETS81142.1 - 0.87 7.6 6.2 0.85 7.6 6.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hexapep PF00132.24 ETS81143.1 - 8.1e-09 34.9 5.7 0.00064 19.4 1.6 4.4 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ETS81143.1 - 0.0015 18.2 3.3 0.36 10.6 1.0 2.9 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 ETS81143.1 - 0.11 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase Oxidored_FMN PF00724.20 ETS81144.1 - 3.5e-89 299.4 0.0 4.1e-89 299.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CsbD PF05532.12 ETS81146.1 - 5.5e-05 23.0 1.2 0.00018 21.3 1.2 1.9 1 1 0 1 1 1 1 CsbD-like LMWPc PF01451.21 ETS81147.1 - 2.6e-41 141.3 0.0 2.9e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase adh_short PF00106.25 ETS81148.1 - 1.2e-38 132.6 0.0 1.5e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS81148.1 - 2.8e-33 115.4 0.0 3.8e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS81148.1 - 3.8e-09 36.7 0.0 6.5e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS81148.1 - 0.0016 17.9 0.0 0.0031 17.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Clr5 PF14420.6 ETS81149.1 - 1.1e-13 51.2 0.1 3.4e-13 49.6 0.1 1.9 1 0 0 1 1 1 1 Clr5 domain TPR_10 PF13374.6 ETS81149.1 - 0.0046 16.8 0.3 0.035 14.0 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ETS81149.1 - 0.031 14.6 0.0 0.18 12.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 ETS81149.1 - 0.13 12.0 0.0 4.1 7.2 0.1 2.5 2 0 0 2 2 2 0 TPR repeat DUF1325 PF07039.11 ETS81150.1 - 2.8e-33 114.8 0.0 4.9e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 ETS81150.1 - 3.8e-05 23.5 0.0 9.5e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain ALIX_LYPXL_bnd PF13949.6 ETS81150.1 - 0.0049 16.2 1.3 0.0073 15.6 1.3 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV PMI_typeI PF01238.21 ETS81151.1 - 4.1e-141 470.5 0.0 4.7e-141 470.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I 5_nucleotid_C PF02872.18 ETS81153.1 - 1e-37 129.8 0.0 1.7e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 ETS81153.1 - 2.1e-07 31.6 0.1 3.4e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IFT43 PF15305.6 ETS81153.1 - 0.038 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Intraflagellar transport protein 43 Fn3_assoc PF13287.6 ETS81153.1 - 0.15 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Fn3 associated Meth_synt_2 PF01717.18 ETS81154.1 - 9.6e-09 34.9 0.0 6.1e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain F-box-like PF12937.7 ETS81155.1 - 2.3e-08 33.8 0.0 8e-08 32.1 0.0 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 ETS81155.1 - 0.0024 17.7 0.3 0.018 14.9 0.3 2.2 1 1 0 1 1 1 1 F-box domain Ank_2 PF12796.7 ETS81156.1 - 6.5e-17 61.9 0.3 3.1e-06 27.7 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS81156.1 - 1.6e-14 54.0 0.3 2.3e-05 24.9 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS81156.1 - 1.7e-12 47.2 0.1 5.2e-05 23.5 0.1 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ETS81156.1 - 3.3e-11 43.2 0.8 8.1e-05 22.8 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS81156.1 - 6.1e-11 41.5 0.0 0.0029 17.9 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 ETS81156.1 - 1.3e-06 28.2 0.4 1.4e-05 24.9 0.4 2.3 1 1 0 1 1 1 1 KilA-N domain Nup88 PF10168.9 ETS81156.1 - 0.074 10.9 1.3 0.13 10.0 1.3 1.3 1 0 0 1 1 1 0 Nuclear pore component Ank_2 PF12796.7 ETS81157.1 - 5.5e-58 193.5 3.9 1.2e-14 54.6 0.0 5.8 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS81157.1 - 5.3e-44 148.0 0.3 6.3e-07 29.8 0.0 8.2 1 1 8 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 ETS81157.1 - 7e-36 121.1 2.8 1.8e-06 28.1 0.1 9.4 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 ETS81157.1 - 1.2e-33 114.8 3.0 3.2e-07 30.5 0.4 7.2 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS81157.1 - 8.5e-33 108.7 0.0 1e-06 28.6 0.0 9.3 9 0 0 9 9 9 6 Ankyrin repeat GATase_7 PF13537.6 ETS81157.1 - 0.037 13.9 0.1 26 4.7 0.0 4.2 5 1 1 6 6 6 0 Glutamine amidotransferase domain Aldo_ket_red PF00248.21 ETS81158.1 - 2e-52 178.2 0.0 2.3e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EamA PF00892.20 ETS81159.1 - 1.1e-10 41.8 29.1 8.4e-07 29.2 3.1 2.7 2 1 0 2 2 2 2 EamA-like transporter family CSG2 PF16965.5 ETS81159.1 - 4.2e-07 29.3 19.8 1.4e-06 27.6 18.1 2.5 1 1 0 1 1 1 1 Ceramide synthase regulator Nuc_sug_transp PF04142.15 ETS81159.1 - 0.017 14.3 0.0 0.017 14.3 0.0 2.1 2 0 0 2 2 2 0 Nucleotide-sugar transporter DUF202 PF02656.15 ETS81159.1 - 9.8 6.7 18.7 1.8 9.0 7.0 4.1 3 2 0 3 3 3 0 Domain of unknown function (DUF202) MFS_1 PF07690.16 ETS81161.1 - 7.7e-32 110.6 23.2 7.7e-32 110.6 23.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS81161.1 - 2.8e-12 46.2 6.6 2.8e-12 46.2 6.6 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter LPD7 PF18821.1 ETS81163.1 - 0.11 12.6 0.5 0.36 11.0 0.5 1.9 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 7 SHE3 PF17078.5 ETS81163.1 - 3.9 7.1 11.0 6.4 6.4 11.0 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Polyketide_cyc2 PF10604.9 ETS81166.1 - 0.052 13.8 0.2 0.061 13.6 0.2 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Cas_Csd1 PF09709.10 ETS81166.1 - 0.087 11.5 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) SGL PF08450.12 ETS81167.1 - 0.00051 19.7 0.8 0.015 14.9 0.1 2.2 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region DUF2993 PF11209.8 ETS81167.1 - 0.092 13.0 0.0 0.21 11.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2993) Oxidored_FMN PF00724.20 ETS81168.1 - 2.6e-40 138.7 0.0 3.3e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF561 PF04481.12 ETS81168.1 - 0.0011 18.2 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF561) Dus PF01207.17 ETS81168.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) GTP_cyclohydro2 PF00925.20 ETS81169.1 - 4.8e-61 205.1 0.0 6.4e-61 204.7 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II NDUF_B7 PF05676.13 ETS81171.1 - 1.4e-29 101.6 3.9 1.7e-29 101.3 3.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 ETS81171.1 - 0.022 14.8 1.9 0.025 14.6 1.5 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Peptidase_S28 PF05577.12 ETS81172.1 - 1.1e-56 192.5 2.0 3e-56 191.1 2.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 DUF2920 PF11144.8 ETS81172.1 - 0.0061 15.8 0.0 0.0082 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) HET PF06985.11 ETS81173.1 - 3.5e-27 95.5 0.0 7e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) VWA PF00092.28 ETS81174.1 - 3.9e-05 24.0 0.0 0.00012 22.4 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 ETS81174.1 - 0.0001 22.9 0.0 0.56 10.9 0.0 3.5 3 0 0 3 3 3 1 von Willebrand factor type A domain zinc_ribbon_4 PF13717.6 ETS81174.1 - 0.00094 19.0 1.5 0.002 18.0 1.5 1.6 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_5 PF13719.6 ETS81174.1 - 0.012 15.3 0.6 0.03 14.1 0.6 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 ETS81174.1 - 0.051 13.6 3.0 0.14 12.2 3.0 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Elf1 PF05129.13 ETS81174.1 - 0.11 12.6 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Peptidase_C1 PF00112.23 ETS81174.1 - 0.14 12.2 0.1 0.69 10.0 0.1 2.0 1 1 0 1 1 1 0 Papain family cysteine protease Gly-zipper_OmpA PF13436.6 ETS81174.1 - 2.9 7.8 21.0 5.8 6.8 14.2 2.4 2 0 0 2 2 2 0 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 ETS81174.1 - 4.5 7.1 15.8 11 5.9 0.1 2.4 2 0 0 2 2 2 0 YMGG-like Gly-zipper Ifi-6-16 PF06140.13 ETS81176.1 - 2.1e-10 40.4 0.2 3.6e-10 39.6 0.2 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF883 PF05957.13 ETS81176.1 - 0.0052 17.4 0.2 0.009 16.6 0.2 1.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) NTP_transf_3 PF12804.7 ETS81176.1 - 0.019 15.3 0.0 0.031 14.6 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain MFS_1 PF07690.16 ETS81177.1 - 2.2e-28 99.2 16.4 2.2e-28 99.2 16.4 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS81177.1 - 1.4e-08 34.1 18.7 2.1e-08 33.5 1.6 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 ETS81177.1 - 0.00018 20.1 1.0 0.00018 20.1 1.0 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TMEM100 PF16311.5 ETS81177.1 - 0.18 11.4 0.5 0.45 10.1 0.2 1.6 1 1 1 2 2 2 0 Transmembrane protein 100 COX7a PF02238.15 ETS81177.1 - 2.1 8.8 7.8 19 5.7 0.1 3.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII Cutinase PF01083.22 ETS81178.1 - 2.9e-48 164.2 5.1 3.6e-48 163.9 5.1 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 ETS81178.1 - 0.00016 21.3 0.6 0.00025 20.7 0.6 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 ETS81178.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Zn_clus PF00172.18 ETS81179.1 - 2.8e-08 33.7 6.2 4.2e-08 33.2 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DDE_3 PF13358.6 ETS81180.1 - 1.2e-14 54.3 0.1 5.9e-14 52.0 0.1 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 ETS81180.1 - 2.6e-10 40.4 0.3 5.8e-10 39.3 0.3 1.6 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 ETS81180.1 - 0.00017 22.1 15.0 0.067 13.8 0.1 4.0 3 2 1 4 4 4 2 Homeodomain-like domain HTH_38 PF13936.6 ETS81180.1 - 0.032 14.0 0.2 0.06 13.1 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Aa_trans PF01490.18 ETS81181.1 - 4.6e-56 190.3 36.9 5.3e-56 190.1 36.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3455 PF11937.8 ETS81182.1 - 1.7e-30 106.5 0.0 2.9e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Pkinase PF00069.25 ETS81183.1 - 2.2e-69 233.8 0.0 2.6e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS81183.1 - 1.1e-31 110.1 0.0 1.5e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ETS81183.1 - 0.0091 15.0 0.0 0.017 14.1 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ETS81183.1 - 0.043 13.2 0.1 0.089 12.1 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ETS81183.1 - 0.066 13.1 0.1 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pro_isomerase PF00160.21 ETS81185.1 - 7e-34 117.4 0.0 1.1e-33 116.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 ETS81185.1 - 1.1e-15 57.2 0.0 2e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_16 PF10294.9 ETS81186.1 - 2.7e-19 69.5 0.0 5.6e-19 68.5 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 ETS81186.1 - 0.0015 19.2 0.0 0.0032 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS81186.1 - 0.0024 17.7 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS81186.1 - 0.003 17.1 0.0 0.006 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 ETS81186.1 - 0.014 15.2 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.19 ETS81186.1 - 0.025 14.3 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 ETS81186.1 - 0.03 13.7 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 ETS81186.1 - 0.079 13.7 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 ETS81186.1 - 0.13 12.0 0.0 0.37 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_31 PF13847.6 ETS81186.1 - 0.17 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_2 PF00890.24 ETS81187.1 - 1.3e-84 284.8 1.1 1.6e-84 284.4 1.1 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 ETS81187.1 - 4.2e-22 78.1 0.0 7.4e-21 74.1 0.0 2.8 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 ETS81187.1 - 7.7e-15 55.3 0.3 1.4e-14 54.5 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ETS81187.1 - 1.8e-10 40.8 0.8 7.2e-10 38.8 0.8 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS81187.1 - 2e-08 34.4 1.6 5.2e-07 29.8 0.4 3.1 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS81187.1 - 1.1e-06 28.1 0.4 1.4e-05 24.5 0.3 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS81187.1 - 3.2e-06 26.1 0.9 0.0078 15.0 0.1 3.3 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 ETS81187.1 - 3.9e-05 23.0 0.0 0.25 10.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS81187.1 - 0.00015 21.1 0.6 0.022 14.0 0.2 2.5 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 ETS81187.1 - 0.00043 19.5 1.9 0.1 11.7 0.8 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ETS81187.1 - 0.001 18.4 5.5 0.012 14.9 5.5 2.1 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 ETS81187.1 - 0.011 15.0 1.1 0.3 10.3 0.2 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 ETS81187.1 - 0.024 15.2 2.9 3.1 8.4 0.7 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ETS81187.1 - 0.057 12.7 0.6 0.11 11.8 0.6 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Med3 PF11593.8 ETS81187.1 - 2.5 7.2 3.9 4.2 6.5 3.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Amino_oxidase PF01593.24 ETS81188.1 - 5.8e-60 203.9 0.1 1.6e-59 202.4 0.1 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ETS81188.1 - 8.8e-09 35.5 0.6 2.1e-08 34.3 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS81188.1 - 0.011 15.0 0.0 0.028 13.6 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS81188.1 - 0.018 14.3 0.2 0.029 13.6 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 ETS81188.1 - 0.031 13.9 0.1 0.34 10.5 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 ETS81188.1 - 0.04 14.0 0.1 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 ETS81188.1 - 0.046 14.3 2.7 0.46 11.1 0.3 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS81188.1 - 0.051 12.6 0.3 0.086 11.9 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ETS81188.1 - 0.057 12.7 0.1 0.14 11.4 0.3 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ETS81188.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 ETS81188.1 - 0.12 11.4 0.7 0.22 10.6 0.7 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 ETS81188.1 - 0.18 10.5 0.4 0.29 9.8 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein Fasciclin PF02469.22 ETS81189.1 - 0.013 15.8 0.0 0.025 14.8 0.0 1.6 1 1 0 1 1 1 0 Fasciclin domain Bap31 PF05529.12 ETS81190.1 - 1e-46 158.2 7.8 1.4e-46 157.7 7.8 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 ETS81190.1 - 8e-16 57.8 2.0 8e-16 57.8 2.0 2.2 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain V_ATPase_I PF01496.19 ETS81190.1 - 0.039 11.9 0.4 0.067 11.1 0.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 ETS81190.1 - 0.053 12.4 2.6 0.078 11.8 2.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 ETS81190.1 - 0.12 12.2 10.1 0.17 11.7 1.7 3.2 2 2 2 4 4 4 0 Septum formation initiator PHR PF08005.12 ETS81190.1 - 0.13 13.0 0.1 0.45 11.2 0.0 1.7 1 1 1 2 2 2 0 PHR domain GPS2_interact PF15784.5 ETS81190.1 - 0.16 12.4 2.6 0.32 11.5 2.5 1.6 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Csm1_N PF18504.1 ETS81190.1 - 0.17 12.2 3.3 0.4 11.1 2.9 1.8 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF2956 PF11169.8 ETS81190.1 - 0.27 11.4 4.7 0.51 10.6 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DUF4337 PF14235.6 ETS81190.1 - 0.72 10.0 3.7 1.4 9.0 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4407 PF14362.6 ETS81190.1 - 1 8.7 4.4 1.8 7.9 4.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HHH PF00633.23 ETS81191.1 - 0.006 16.4 0.1 0.019 14.8 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif NAC PF01849.18 ETS81191.1 - 0.066 13.2 0.3 0.14 12.2 0.1 1.6 2 0 0 2 2 2 0 NAC domain zf-met2 PF12907.7 ETS81192.1 - 2.2e-15 56.5 3.4 3.2e-15 56.0 3.4 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 ETS81192.1 - 2.7e-07 31.3 8.9 2.7e-07 31.3 8.9 1.6 2 0 0 2 2 2 1 4F5 protein family HypA PF01155.19 ETS81192.1 - 0.043 13.8 0.6 0.051 13.6 0.6 1.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_5 PF13719.6 ETS81192.1 - 0.092 12.5 4.2 4.6 7.1 0.9 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DIOX_N PF14226.6 ETS81193.1 - 5.1e-31 107.9 0.0 1.1e-30 106.8 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS81193.1 - 1.2e-14 54.6 0.0 4e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 ETS81194.1 - 5.1e-07 30.3 7.7 0.021 15.7 0.2 6.0 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS81194.1 - 0.0011 19.2 0.1 1.2 9.5 0.0 4.3 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain SOAR PF16533.5 ETS81194.1 - 6 6.9 6.6 5.1 7.1 1.4 2.3 2 0 0 2 2 2 0 STIM1 Orai1-activating region RNA_pol_N PF01194.17 ETS81195.1 - 8.9e-31 106.0 0.8 1.1e-30 105.7 0.8 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 ETS81195.1 - 0.042 14.1 0.2 0.072 13.4 0.2 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Helo_like_N PF17111.5 ETS81196.1 - 0.12 11.7 1.0 2.4 7.5 0.0 2.8 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins HAD_2 PF13419.6 ETS81198.1 - 0.0001 22.4 0.0 0.00021 21.4 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETS81198.1 - 0.0009 19.6 0.0 0.016 15.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RRN9 PF10680.9 ETS81199.1 - 4.7e-17 62.0 0.7 1.7e-16 60.2 0.7 2.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2 PF00096.26 ETS81199.1 - 0.54 10.8 3.0 0.43 11.1 0.9 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type PI3K_1B_p101 PF10486.9 ETS81199.1 - 0.72 7.6 6.1 7 4.3 3.0 2.1 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pescadillo_N PF06732.11 ETS81200.1 - 1.5e-121 405.2 0.1 3e-121 404.1 0.1 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 ETS81200.1 - 0.00025 21.4 0.0 0.0008 19.8 0.0 1.9 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PIG-U PF06728.13 ETS81201.1 - 2.8e-119 398.6 29.8 3.2e-119 398.4 29.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.13 ETS81201.1 - 0.00032 20.7 5.6 0.00051 20.0 5.5 1.5 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) tRNA-synt_1 PF00133.22 ETS81202.1 - 7e-160 533.2 0.0 1e-159 532.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 ETS81202.1 - 3.5e-21 75.4 0.0 5.9e-12 45.0 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 ETS81202.1 - 1.3e-15 57.6 0.0 2.6e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 ETS81202.1 - 0.00013 21.5 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.14 ETS81202.1 - 0.01 15.7 2.2 0.022 14.6 2.2 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.19 ETS81202.1 - 0.011 15.1 0.0 0.96 8.7 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Tom37 PF10568.9 ETS81204.1 - 1.1e-33 116.2 0.4 1.6e-33 115.7 0.4 1.2 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 ETS81204.1 - 7.7e-06 26.6 0.0 1.7e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 ETS81204.1 - 8.9e-06 25.4 0.1 2.5e-05 24.0 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ETS81204.1 - 0.00027 20.9 0.1 0.0015 18.5 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ETS81204.1 - 0.056 13.8 0.0 0.17 12.2 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ETS81204.1 - 0.082 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Sugar_tr PF00083.24 ETS81205.1 - 4.4e-78 263.2 24.7 5.1e-78 262.9 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS81205.1 - 4.3e-32 111.4 53.2 9.4e-30 103.7 30.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 ETS81205.1 - 0.061 13.9 1.9 0.21 12.2 1.9 1.9 1 0 0 1 1 1 0 Phage holin family 2 Exo_endo_phos PF03372.23 ETS81206.1 - 1.3e-09 37.9 0.1 1.9e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 ETS81206.1 - 0.016 15.1 0.0 0.039 13.8 0.0 1.7 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase SPRY PF00622.28 ETS81208.1 - 4.3e-07 30.1 0.0 7.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Na_Ca_ex PF01699.24 ETS81209.1 - 2.4e-41 141.2 38.5 1.1e-20 74.1 12.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein AP3D1 PF06375.11 ETS81209.1 - 9.1 6.5 9.9 10 6.3 3.5 2.4 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 MFS_1 PF07690.16 ETS81210.1 - 2.4e-24 85.9 56.4 3.1e-20 72.4 35.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cep57_MT_bd PF06657.13 ETS81211.1 - 3.7e-21 75.4 0.2 3.7e-21 75.4 0.2 4.6 4 1 2 6 6 6 1 Centrosome microtubule-binding domain of Cep57 ZapB PF06005.12 ETS81211.1 - 0.0016 18.9 42.9 0.13 12.7 1.4 6.6 2 1 4 6 6 6 4 Cell division protein ZapB Glyco_transf_29 PF00777.18 ETS81211.1 - 0.028 13.8 0.0 0.084 12.3 0.0 1.8 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) YabA PF06156.13 ETS81211.1 - 0.12 13.0 29.8 4.6 7.9 1.7 5.9 1 1 3 4 4 4 0 Initiation control protein YabA HALZ PF02183.18 ETS81211.1 - 0.65 10.3 24.7 1.1 9.5 1.7 5.6 4 1 0 4 4 4 0 Homeobox associated leucine zipper DUF1772 PF08592.11 ETS81214.1 - 1.6e-24 86.7 7.1 2.3e-24 86.2 7.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Nup_retrotrp_bd PF10599.9 ETS81214.1 - 0.017 15.8 0.4 0.031 14.9 0.4 1.5 1 0 0 1 1 1 0 Retro-transposon transporting motif Acetyltransf_3 PF13302.7 ETS81215.1 - 1.4e-35 122.9 0.0 1.9e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS81215.1 - 0.00038 20.7 0.1 0.0047 17.2 0.1 2.2 1 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 ETS81215.1 - 0.12 12.6 0.0 13 5.8 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Fungal_trans PF04082.18 ETS81216.1 - 1.4e-19 70.2 0.2 2.9e-19 69.1 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS81216.1 - 5.5e-07 29.6 12.6 9.4e-07 28.9 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Atg14 PF10186.9 ETS81216.1 - 0.053 12.6 5.4 0.11 11.5 5.4 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SUIM_assoc PF16619.5 ETS81216.1 - 0.069 13.2 1.7 0.17 11.9 1.7 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_L18A PF01775.17 ETS81217.1 - 1.8e-44 150.7 0.6 2.4e-44 150.3 0.6 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PCI PF01399.27 ETS81218.1 - 1.6e-14 54.3 0.0 1.1e-13 51.6 0.0 2.2 1 1 1 2 2 2 1 PCI domain CCDC32 PF14989.6 ETS81218.1 - 0.025 14.6 0.1 0.045 13.7 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing 32 BTB PF00651.31 ETS81219.1 - 2.6e-07 30.9 0.1 1e-06 28.9 0.0 2.0 3 0 0 3 3 3 1 BTB/POZ domain Skp1_POZ PF03931.15 ETS81219.1 - 0.2 11.9 0.0 0.95 9.7 0.0 2.1 3 0 0 3 3 3 0 Skp1 family, tetramerisation domain DUF3070 PF11270.8 ETS81220.1 - 0.0017 18.5 4.6 0.54 10.5 0.5 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3070) WD40 PF00400.32 ETS81222.1 - 1.2e-18 67.0 10.8 0.00083 20.1 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS81222.1 - 1.1e-14 54.4 0.0 0.00039 20.7 0.0 5.5 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ETS81222.1 - 2e-05 24.6 0.0 0.036 14.0 0.0 3.5 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.10 ETS81222.1 - 0.0017 18.1 0.1 0.0055 16.5 0.1 1.9 1 0 0 1 1 1 1 HIRA B motif PSII_BNR PF14870.6 ETS81222.1 - 0.13 11.5 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 PD40 PF07676.12 ETS81222.1 - 0.22 11.5 3.0 5.1 7.2 0.6 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat ABC_tran PF00005.27 ETS81223.1 - 6.5e-50 169.2 0.0 2.2e-28 99.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 ETS81223.1 - 1.7e-41 142.7 23.0 3.5e-28 99.0 9.6 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 ETS81223.1 - 2.7e-09 36.8 0.0 0.0012 18.4 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ETS81223.1 - 0.00031 20.7 1.6 0.16 11.9 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 ETS81223.1 - 0.00061 19.5 0.5 0.68 9.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ETS81223.1 - 0.00092 19.3 0.4 0.11 12.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 ETS81223.1 - 0.0013 19.3 1.1 0.073 13.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain T2SSE PF00437.20 ETS81223.1 - 0.003 16.7 0.0 1.5 7.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 ETS81223.1 - 0.004 17.4 0.1 3.8 7.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 ETS81223.1 - 0.016 14.8 0.0 1.9 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ETS81223.1 - 0.016 15.6 1.3 0.7 10.3 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain DUF87 PF01935.17 ETS81223.1 - 0.036 14.2 1.8 1.6 8.8 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 ETS81223.1 - 0.046 13.4 0.1 1.5 8.5 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein MeaB PF03308.16 ETS81223.1 - 0.07 12.1 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 ETS81223.1 - 0.15 11.3 0.2 2 7.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_21 PF13304.6 ETS81223.1 - 0.19 11.5 0.7 25 4.6 0.1 3.5 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Asp PF00026.23 ETS81224.1 - 8.8e-73 245.5 1.3 1.1e-72 245.2 1.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS81224.1 - 5.1e-11 43.1 4.8 2.8e-06 27.7 0.1 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ETS81224.1 - 1.8e-06 28.5 2.7 0.00078 20.0 0.4 3.6 3 1 0 3 3 3 2 Aspartyl protease WLM PF08325.10 ETS81225.1 - 2.6e-65 220.1 0.2 4.6e-65 219.3 0.2 1.4 1 0 0 1 1 1 1 WLM domain zf-Sec23_Sec24 PF04810.15 ETS81225.1 - 0.0009 19.2 5.0 0.23 11.5 0.3 3.4 2 1 1 3 3 3 2 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 ETS81225.1 - 0.0037 16.5 4.6 0.0037 16.5 4.6 3.3 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others C1_2 PF03107.16 ETS81225.1 - 0.43 10.9 9.4 0.72 10.2 0.9 2.5 2 0 0 2 2 2 0 C1 domain DUF45 PF01863.17 ETS81225.1 - 1.8 8.5 4.0 4.7 7.2 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF45 HATPase_c PF02518.26 ETS81226.1 - 1.6e-28 99.5 0.2 3.4e-28 98.4 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ETS81226.1 - 1.8e-21 76.4 0.4 4.5e-21 75.1 0.4 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ETS81226.1 - 4.2e-21 74.8 0.1 1.5e-20 73.0 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 ETS81226.1 - 1.6e-17 63.6 0.1 4.4e-17 62.2 0.1 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 ETS81226.1 - 2.6e-08 34.0 0.0 0.00022 21.4 0.0 4.5 4 0 0 4 4 4 1 PAS domain PAS_4 PF08448.10 ETS81226.1 - 1.8e-07 31.4 0.2 0.0002 21.6 0.0 4.0 4 0 0 4 4 4 1 PAS fold PAS PF00989.25 ETS81226.1 - 1.1e-06 28.6 0.0 0.055 13.5 0.0 4.1 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.7 ETS81226.1 - 2.9e-06 27.1 0.0 0.0029 17.6 0.1 3.0 2 0 0 2 2 2 2 PAS domain HATPase_c_3 PF13589.6 ETS81226.1 - 0.019 14.8 0.0 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toxin_10 PF05431.11 ETS81226.1 - 0.037 13.5 0.0 0.098 12.1 0.0 1.7 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 MLTR_LBD PF17765.1 ETS81226.1 - 0.04 14.0 1.4 0.11 12.6 0.1 2.4 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain MMM1 PF10296.9 ETS81228.1 - 9.7e-08 31.4 0.0 2e-07 30.4 0.0 1.4 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 CDC45 PF02724.14 ETS81228.1 - 1.5 7.1 5.1 4.9 5.3 0.0 2.7 3 0 0 3 3 3 0 CDC45-like protein FAM176 PF14851.6 ETS81228.1 - 4.8 6.8 13.6 8.8 6.0 0.9 3.1 3 0 0 3 3 3 0 FAM176 family GCIP PF13324.6 ETS81228.1 - 4.9 6.7 11.2 3.5 7.1 0.7 2.8 3 0 0 3 3 3 0 Grap2 and cyclin-D-interacting Spt5_N PF11942.8 ETS81228.1 - 7.8 7.6 35.1 2.8 9.0 7.2 3.3 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal DUF4611 PF15387.6 ETS81228.1 - 8.3 6.7 20.4 5.7 7.2 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) PIP5K PF01504.18 ETS81229.1 - 6.4e-36 124.0 0.2 1.1e-27 97.0 0.6 2.7 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 ETS81229.1 - 3.8e-22 78.6 0.0 7.1e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 ETS81229.1 - 8.2e-12 45.1 10.5 2.1e-11 43.8 10.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger CEP63 PF17045.5 ETS81230.1 - 0.039 13.8 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa IF4E PF01652.18 ETS81231.1 - 3.8e-53 179.5 0.2 4.8e-53 179.2 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.28 ETS81232.1 - 2.8e-68 230.4 0.1 5.8e-34 117.4 0.1 2.1 1 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 ETS81232.1 - 6.8e-13 49.4 0.2 3.8e-12 47.0 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain BolA PF01722.18 ETS81233.1 - 5.2e-30 103.5 0.9 9.3e-30 102.7 0.9 1.4 1 0 0 1 1 1 1 BolA-like protein DUF726 PF05277.12 ETS81234.1 - 1.3e-119 399.1 0.1 1.8e-119 398.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) LCAT PF02450.15 ETS81234.1 - 0.0031 16.8 0.0 0.0043 16.3 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase CRA_rpt PF07046.11 ETS81234.1 - 0.033 14.4 4.1 0.12 12.5 4.1 2.0 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat Thioesterase PF00975.20 ETS81234.1 - 0.035 14.2 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PE-PPE PF08237.11 ETS81234.1 - 0.11 12.1 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain DUF900 PF05990.12 ETS81234.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Glyco_hydro_36N PF16875.5 ETS81235.1 - 1.5e-06 28.0 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_67M PF07488.12 ETS81236.1 - 1.6e-136 454.7 0.0 2e-136 454.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67N PF03648.14 ETS81236.1 - 3.3e-26 92.0 0.0 5.4e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_67C PF07477.12 ETS81236.1 - 2.2e-13 50.3 0.0 3.4e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67C PF07477.12 ETS81237.1 - 1.2e-51 175.5 0.1 1.5e-51 175.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus DUF3419 PF11899.8 ETS81238.1 - 1.2e-163 544.8 0.0 1.6e-163 544.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 ETS81238.1 - 4.9e-13 49.2 0.0 6.2e-12 45.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS81238.1 - 2.7e-10 40.9 0.0 6.1e-09 36.5 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS81238.1 - 1.3e-09 38.7 0.0 1e-06 29.4 0.0 4.0 3 1 1 4 4 4 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS81238.1 - 2.3e-07 30.4 0.0 0.00028 20.3 0.0 2.7 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 ETS81238.1 - 3.7e-07 30.7 0.0 0.00018 22.1 0.0 4.0 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS81238.1 - 9.8e-07 28.7 0.0 9.3e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 ETS81238.1 - 0.0024 17.7 0.0 0.0057 16.4 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ada3 PF10198.9 ETS81239.1 - 2.7e-56 189.4 1.2 3.5e-56 189.0 0.0 1.8 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 LRIF1 PF15741.5 ETS81239.1 - 0.21 10.1 7.6 0.082 11.4 4.8 1.6 2 0 0 2 2 2 0 Ligand-dependent nuclear receptor-interacting factor 1 SAPS PF04499.15 ETS81239.1 - 5.9 5.6 5.5 11 4.7 5.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Amidohydro_1 PF01979.20 ETS81240.1 - 8.2e-77 258.8 0.4 3.1e-76 256.9 0.2 1.9 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.20 ETS81240.1 - 7.4e-56 187.7 6.1 5.3e-55 184.9 3.5 2.5 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 ETS81240.1 - 4e-42 142.2 0.1 8.4e-42 141.2 0.1 1.6 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 ETS81240.1 - 1.6e-39 134.1 0.3 5.1e-39 132.6 0.1 2.0 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_3 PF07969.11 ETS81240.1 - 2.5e-09 37.1 0.1 1.1e-05 25.1 0.0 2.5 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 ETS81240.1 - 0.00078 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase HMG_box PF00505.19 ETS81241.1 - 2.9e-06 27.6 0.1 2.9e-06 27.6 0.1 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ETS81241.1 - 0.00039 20.9 0.0 0.0015 19.1 0.0 2.0 1 0 0 1 1 1 1 HMG-box domain Het-C PF07217.11 ETS81242.1 - 9.2e-234 777.1 0.0 1.2e-233 776.8 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Glyco_hydro_45 PF02015.16 ETS81243.1 - 3.7e-73 245.9 20.9 4.4e-73 245.7 20.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 zf-RING_2 PF13639.6 ETS81244.1 - 5.5e-11 42.6 5.8 9.9e-11 41.8 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ETS81244.1 - 7.6e-09 35.3 4.8 1.3e-08 34.5 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ETS81244.1 - 1.8e-06 27.6 6.0 1.8e-06 27.6 6.0 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 ETS81244.1 - 2.2e-06 27.4 5.2 4e-06 26.6 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ETS81244.1 - 1.7e-05 24.7 4.0 3e-05 23.9 4.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ETS81244.1 - 2.4e-05 24.5 2.5 6.5e-05 23.1 2.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ETS81244.1 - 6.4e-05 22.9 8.4 7.9e-05 22.6 2.4 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ETS81244.1 - 0.00091 19.0 3.1 0.0017 18.2 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ETS81244.1 - 0.0012 18.6 4.6 0.0026 17.6 4.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ETS81244.1 - 0.0012 18.9 7.2 0.0028 17.8 7.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 ETS81244.1 - 0.0054 16.8 1.0 0.017 15.2 1.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger YdjO PF14169.6 ETS81244.1 - 0.051 13.3 0.3 7.6 6.4 0.0 3.2 3 0 0 3 3 3 0 Cold-inducible protein YdjO Zn_ribbon_17 PF17120.5 ETS81244.1 - 0.11 12.1 1.9 0.21 11.3 1.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 ETS81244.1 - 0.76 10.0 3.3 3.2 8.0 3.3 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Glyco_hydro_47 PF01532.20 ETS81245.1 - 3.5e-172 573.4 0.0 4e-172 573.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlcNAc_2-epim PF07221.11 ETS81245.1 - 0.07 12.4 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Clr5 PF14420.6 ETS81247.1 - 1.9e-20 72.8 2.8 1.9e-20 72.8 2.8 2.1 2 0 0 2 2 2 1 Clr5 domain TPR_8 PF13181.6 ETS81247.1 - 0.053 13.8 0.9 19 5.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS81247.1 - 0.061 12.7 0.2 4.2 6.6 0.0 2.2 1 1 0 2 2 2 0 MalT-like TPR region SPT_ssu-like PF11779.8 ETS81248.1 - 7.7e-23 79.9 3.0 1.1e-22 79.4 3.0 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like p450 PF00067.22 ETS81249.1 - 6.8e-65 219.6 0.0 7.9e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phospholip_A2_3 PF09056.11 ETS81250.1 - 6e-40 136.3 0.2 7.6e-40 136.0 0.2 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Maf PF02545.14 ETS81251.1 - 7.4e-48 162.5 0.0 8.7e-48 162.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein HLH PF00010.26 ETS81252.1 - 6.1e-09 35.7 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Methyltransf_17 PF12692.7 ETS81252.1 - 0.011 15.8 0.3 0.015 15.3 0.3 1.2 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase tRNA-synt_2b PF00587.25 ETS81253.1 - 1.7e-32 112.8 0.0 6.1e-31 107.8 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ETS81253.1 - 2.3e-09 37.3 0.1 4.6e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TRP PF06011.12 ETS81255.1 - 1.1e-152 508.7 25.6 1.3e-152 508.4 25.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 ETS81255.1 - 3.7e-42 144.0 5.3 5.9e-42 143.3 5.3 1.3 1 0 0 1 1 1 1 ML-like domain COesterase PF00135.28 ETS81256.1 - 7.2e-74 249.5 4.6 1.7e-73 248.3 4.6 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS81256.1 - 8.2e-06 25.8 0.2 2.4e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS81256.1 - 0.014 14.8 0.3 0.035 13.6 0.3 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1749 PF08538.10 ETS81256.1 - 0.12 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Utp11 PF03998.13 ETS81257.1 - 6.4e-61 206.4 15.0 7.3e-61 206.2 15.0 1.0 1 0 0 1 1 1 1 Utp11 protein RRN3 PF05327.11 ETS81257.1 - 1.3 7.5 5.3 1.7 7.1 5.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DAO PF01266.24 ETS81259.1 - 1.4e-29 103.8 0.0 1.6e-29 103.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS81259.1 - 3.7e-06 26.3 0.1 5.3e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ETS81259.1 - 0.00018 22.0 0.1 0.00033 21.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ETS81259.1 - 0.00056 19.6 0.0 0.00094 18.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 ETS81259.1 - 0.0024 18.1 0.3 0.0063 16.7 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS81259.1 - 0.0032 16.8 0.0 0.0044 16.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 ETS81259.1 - 0.014 14.9 0.0 0.45 9.9 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase FAD_binding_3 PF01494.19 ETS81259.1 - 0.019 14.2 1.2 0.028 13.7 0.4 1.6 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 ETS81259.1 - 0.021 14.4 0.2 0.033 13.7 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.6 ETS81259.1 - 0.021 14.1 0.6 0.032 13.5 0.6 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ETS81259.1 - 0.024 15.0 0.0 0.036 14.5 0.0 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 ETS81259.1 - 0.027 13.6 0.1 0.043 12.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 ETS81259.1 - 0.036 14.3 0.1 0.075 13.3 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 ETS81259.1 - 0.048 12.3 0.9 0.07 11.8 0.9 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 ETS81259.1 - 0.088 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ETS81259.1 - 0.091 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ETS81259.1 - 0.093 13.3 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 ETS81259.1 - 0.12 11.7 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_transf_4 PF13439.6 ETS81259.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 FAD_oxidored PF12831.7 ETS81259.1 - 0.24 10.7 0.9 0.38 10.1 0.9 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase CVNH PF08881.10 ETS81260.1 - 0.0058 17.3 0.1 0.01 16.5 0.0 1.5 1 1 0 1 1 1 1 CVNH domain TMEM132D_C PF15706.5 ETS81261.1 - 0.17 11.7 0.2 0.36 10.6 0.2 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term NACHT PF05729.12 ETS81262.1 - 1.2e-10 41.5 0.0 2.5e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain zf-C2H2 PF00096.26 ETS81262.1 - 1.3e-08 34.8 19.3 0.00069 19.9 4.9 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type AAA_16 PF13191.6 ETS81262.1 - 2.1e-06 28.2 0.0 1.3e-05 25.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS81262.1 - 6.2e-05 23.3 0.0 0.00016 21.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain zf-H2C2_2 PF13465.6 ETS81262.1 - 0.00098 19.4 14.4 0.029 14.8 1.8 3.2 3 0 0 3 3 2 2 Zinc-finger double domain AAA PF00004.29 ETS81262.1 - 0.0011 19.4 0.0 0.0027 18.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF676 PF05057.14 ETS81262.1 - 0.0019 17.8 0.0 0.0075 15.8 0.0 1.9 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 ETS81262.1 - 0.0022 18.6 0.0 0.008 16.8 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family KAP_NTPase PF07693.14 ETS81262.1 - 0.0049 16.1 0.1 1.6 7.9 0.0 2.5 1 1 1 2 2 2 1 KAP family P-loop domain NB-ARC PF00931.22 ETS81262.1 - 0.0063 15.7 0.0 0.034 13.3 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain zf-C2H2_4 PF13894.6 ETS81262.1 - 0.0067 17.2 20.5 0.23 12.4 4.3 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger AAA_30 PF13604.6 ETS81262.1 - 0.0098 15.6 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cutinase PF01083.22 ETS81262.1 - 0.023 14.7 0.2 3 7.8 0.0 3.1 3 0 0 3 3 3 0 Cutinase Hydrolase_4 PF12146.8 ETS81262.1 - 0.034 13.4 0.0 0.54 9.5 0.0 2.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 AAA_7 PF12775.7 ETS81262.1 - 0.037 13.5 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AFG1_ATPase PF03969.16 ETS81262.1 - 0.044 12.7 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase DUF2075 PF09848.9 ETS81262.1 - 0.086 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.23 ETS81262.1 - 0.19 11.9 0.0 0.95 9.6 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase zf-C2H2_11 PF16622.5 ETS81262.1 - 1.1 9.1 7.8 0.21 11.4 1.3 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Peptidase_M16 PF00675.20 ETS81263.1 - 2.5e-55 186.6 0.4 7.9e-55 184.9 0.2 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ETS81263.1 - 1.6e-34 119.5 0.0 3.8e-34 118.3 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Esterase PF00756.20 ETS81263.1 - 0.072 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Putative esterase Raffinose_syn PF05691.12 ETS81264.1 - 7.9e-60 202.5 1.5 1.3e-53 181.9 0.5 3.1 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Epimerase PF01370.21 ETS81265.1 - 7.9e-09 35.3 0.0 0.0029 17.1 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS81265.1 - 4.8e-08 33.1 0.0 8.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 ETS81265.1 - 0.00012 22.6 0.0 0.00029 21.3 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 ETS81265.1 - 0.0008 18.5 0.0 0.5 9.3 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 ETS81265.1 - 0.017 15.4 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 ETS81265.1 - 0.026 13.9 0.0 0.51 9.7 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ETS81265.1 - 0.095 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 ETS81266.1 - 4.4e-18 65.6 0.0 1.2e-17 64.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS81266.1 - 5e-13 49.4 0.0 7.2e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ETS81266.1 - 1.1e-11 44.2 0.0 6.9e-11 41.7 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ETS81266.1 - 1.8e-09 37.5 0.1 5.7e-08 32.5 0.0 2.7 2 1 1 3 3 3 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ETS81266.1 - 1e-07 31.8 0.0 1.4e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 ETS81266.1 - 1.4e-05 24.4 0.0 0.0043 16.2 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 ETS81266.1 - 0.0001 21.5 0.0 0.00015 21.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 ETS81266.1 - 0.00039 19.9 0.0 0.0022 17.5 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS81266.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Tautomerase_3 PF14832.6 ETS81267.1 - 9.2e-54 181.4 0.0 1e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme ABC_tran PF00005.27 ETS81268.1 - 5.3e-46 156.5 0.0 1.3e-26 93.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS81268.1 - 1.1e-36 127.0 37.7 8.9e-29 101.0 14.7 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 ETS81268.1 - 1.9e-08 34.5 0.2 0.035 13.9 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETS81268.1 - 4.1e-08 32.9 7.6 0.0019 17.7 0.1 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ETS81268.1 - 7.8e-05 22.7 0.2 0.17 12.0 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETS81268.1 - 8.6e-05 22.5 0.8 0.0041 17.1 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 ETS81268.1 - 0.00052 19.7 2.7 0.5 10.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ETS81268.1 - 0.00084 19.6 0.5 0.16 12.2 0.1 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 ETS81268.1 - 0.0011 18.6 2.3 0.63 9.6 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 ETS81268.1 - 0.0013 19.1 0.1 0.078 13.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 ETS81268.1 - 0.0018 17.9 0.1 0.095 12.3 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 ETS81268.1 - 0.0058 16.8 0.0 0.12 12.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ETS81268.1 - 0.0095 15.7 2.4 0.91 9.2 0.1 3.2 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 ETS81268.1 - 0.028 14.1 0.3 2.4 7.8 0.1 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 ETS81268.1 - 0.05 14.0 0.1 0.94 9.9 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 ETS81268.1 - 0.081 13.5 0.0 3.8 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 ETS81268.1 - 0.1 11.7 0.2 11 5.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 ETS81268.1 - 0.11 13.0 3.0 4.4 7.8 0.4 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ETS81268.1 - 0.13 11.8 0.3 17 4.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_15 PF13175.6 ETS81268.1 - 0.13 12.0 0.5 3.8 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 ETS81268.1 - 0.14 11.0 0.9 9.3 5.0 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.23 ETS81268.1 - 0.31 11.1 4.6 0.67 10.0 0.3 2.8 2 1 0 3 3 3 0 Dynamin family Spore_IV_A PF09547.10 ETS81268.1 - 0.34 9.8 0.5 0.94 8.3 0.0 1.9 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) DUF87 PF01935.17 ETS81268.1 - 0.89 9.6 2.8 0.59 10.2 0.2 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain DUF455 PF04305.14 ETS81271.1 - 0.2 11.1 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF455) Hexokinase_1 PF00349.21 ETS81272.1 - 0.022 14.6 0.3 0.029 14.3 0.3 1.1 1 0 0 1 1 1 0 Hexokinase FAD_binding_4 PF01565.23 ETS81274.1 - 1.2e-20 73.7 3.7 2.5e-20 72.6 3.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS81274.1 - 0.0026 17.8 0.0 0.0075 16.3 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like HET PF06985.11 ETS81275.1 - 1.6e-11 44.8 3.4 3.9e-08 33.8 0.1 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) GATase PF00117.28 ETS81276.1 - 0.022 14.5 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I ThiJ_like PF17124.5 ETS81276.1 - 0.094 12.4 0.0 0.16 11.6 0.0 1.3 1 1 0 1 1 1 0 ThiJ/PfpI family-like MFS_1 PF07690.16 ETS81277.1 - 3.3e-27 95.4 33.6 3.3e-27 95.4 33.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ETS81277.1 - 0.00053 19.4 7.6 0.00053 19.4 7.6 2.1 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF21 PF01595.20 ETS81279.1 - 0.32 10.7 2.7 0.79 9.4 2.7 1.6 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain DUF973 PF06157.11 ETS81279.1 - 2.5 7.1 9.1 4.1 6.4 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Collar PF07484.12 ETS81280.1 - 6.7e-37 125.3 10.6 7.2e-15 54.7 1.4 4.1 3 1 0 3 3 3 3 Phage Tail Collar Domain Acetyltransf_10 PF13673.7 ETS81281.1 - 1.9e-08 34.3 0.0 0.0012 18.8 0.0 2.1 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS81281.1 - 3.3e-08 33.8 0.6 9.4e-08 32.3 0.6 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS81281.1 - 5.9e-05 23.4 0.0 9.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ank_2 PF12796.7 ETS81283.1 - 4.7e-23 81.6 0.0 9.4e-08 32.5 0.0 5.2 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS81283.1 - 6.7e-20 69.1 0.4 0.047 14.2 0.0 9.8 10 1 0 10 10 10 4 Ankyrin repeat Ank_4 PF13637.6 ETS81283.1 - 4.3e-18 65.4 1.0 0.001 19.6 0.0 6.9 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 ETS81283.1 - 1.2e-17 63.4 1.1 0.072 13.6 0.0 7.7 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 ETS81283.1 - 1.8e-12 47.2 5.1 0.13 12.6 0.0 7.7 6 2 3 9 9 9 4 Ankyrin repeats (many copies) Epimerase PF01370.21 ETS81284.1 - 1.2e-09 38.0 0.0 1.5e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS81284.1 - 5.5e-09 35.4 0.0 6.7e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ETS81284.1 - 2.8e-05 24.1 0.0 9.7e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS81284.1 - 0.00026 20.6 0.0 0.00045 19.8 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 ETS81284.1 - 0.00032 20.2 0.0 0.00044 19.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 ETS81284.1 - 0.0032 16.9 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.12 ETS81284.1 - 0.16 11.1 0.4 1.8 7.6 0.4 2.0 1 1 0 1 1 1 0 Male sterility protein Epimerase PF01370.21 ETS81285.1 - 1.3e-12 47.7 0.1 8e-12 45.1 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS81285.1 - 2.4e-07 30.0 0.0 5.5e-07 28.9 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ETS81285.1 - 1.3e-05 24.8 0.0 9.9e-05 21.9 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ETS81285.1 - 0.00011 22.2 0.0 0.00031 20.7 0.0 1.8 2 1 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 ETS81285.1 - 0.0028 17.1 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase Polysacc_synt_2 PF02719.15 ETS81285.1 - 0.0058 15.8 0.0 0.0085 15.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ETS81285.1 - 0.0068 16.0 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 ETS81285.1 - 0.021 14.0 0.0 0.19 10.9 0.0 2.0 1 1 0 1 1 1 0 Male sterility protein Pkinase PF00069.25 ETS81286.1 - 2.6e-67 227.0 0.0 3.2e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS81286.1 - 1e-30 106.9 0.0 1.4e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ETS81286.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ETS81286.1 - 0.2 10.5 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF1713 PF08213.11 ETS81287.1 - 1.7e-10 40.6 20.8 1.7e-10 40.6 20.8 2.2 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 ETS81287.1 - 0.047 14.4 0.3 0.25 12.0 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial protein Pet20 DUF3106 PF11304.8 ETS81287.1 - 0.87 10.1 9.9 2 9.0 7.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Arginase PF00491.21 ETS81288.1 - 1e-80 271.2 0.1 1.2e-80 271.0 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 ETS81288.1 - 0.085 13.1 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 UPF0489 domain APH PF01636.23 ETS81289.1 - 1.8e-18 67.4 0.1 2.2e-18 67.1 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETS81289.1 - 0.00025 20.7 0.0 0.00039 20.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 ETS81289.1 - 0.063 12.6 0.0 0.13 11.6 0.0 1.4 2 0 0 2 2 2 0 Protein kinase domain Thioredoxin_4 PF13462.6 ETS81290.1 - 1.4e-06 28.6 0.0 3.1e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin Phage_TAC_6 PF09550.10 ETS81290.1 - 0.062 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC DSBA PF01323.20 ETS81290.1 - 0.074 12.8 5.0 3.1 7.5 0.2 2.9 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_12 PF18400.1 ETS81290.1 - 0.094 12.6 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Mur_ligase_M PF08245.12 ETS81292.1 - 0.12 12.4 0.2 1.1 9.2 0.2 2.2 1 1 0 1 1 1 0 Mur ligase middle domain Mur_ligase_C PF02875.21 ETS81292.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Coatomer_b_Cpla PF14806.6 ETS81292.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Mur_ligase_C PF02875.21 ETS81293.1 - 0.023 15.0 0.2 0.074 13.3 0.0 1.9 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 ETS81293.1 - 0.054 13.5 0.0 6.4 6.7 0.0 2.5 2 1 0 2 2 2 0 Mur ligase middle domain Succ_CoA_lig PF13607.6 ETS81293.1 - 0.096 12.5 0.6 0.27 11.0 0.6 1.7 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain DUF5375 PF17345.2 ETS81293.1 - 0.14 12.0 0.7 0.39 10.6 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5375) CTP_synth_N PF06418.14 ETS81294.1 - 3.8e-108 360.8 0.0 4.9e-108 360.4 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 ETS81294.1 - 9.8e-53 178.7 0.0 1.4e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ETS81294.1 - 3.9e-07 30.0 0.1 9.9e-07 28.7 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 ETS81294.1 - 0.041 13.9 0.0 0.054 13.5 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain CNDH2_C PF16858.5 ETS81296.1 - 0.0042 17.0 0.5 0.007 16.3 0.5 1.3 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop14 PF04147.12 ETS81296.1 - 0.089 11.0 7.4 0.11 10.7 7.4 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 ETS81296.1 - 2.7 6.2 7.6 3.6 5.7 7.6 1.2 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 ETS81297.1 - 1.5e-35 122.8 30.3 5.6e-35 120.9 29.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS81297.1 - 0.045 12.6 17.8 0.028 13.3 13.6 2.2 1 1 2 3 3 3 0 MFS_1 like family AMP-binding PF00501.28 ETS81298.1 - 8.8e-74 248.6 0.0 1.1e-73 248.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 ETS81298.1 - 8e-20 70.5 0.3 2.5e-19 68.9 0.3 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 ETS81298.1 - 6.1e-16 59.2 0.0 1.3e-15 58.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BRCT_2 PF16589.5 ETS81299.1 - 1.3e-07 31.9 0.0 2.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 ETS81299.1 - 0.00035 20.5 0.0 0.001 19.0 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 ETS81299.1 - 0.0033 17.8 0.0 0.0064 16.9 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 ETS81299.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain KilA-N PF04383.13 ETS81300.1 - 0.00057 19.7 0.0 0.009 15.9 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain EHN PF06441.12 ETS81301.1 - 2.5e-37 127.5 0.4 8.8e-36 122.6 0.0 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ETS81301.1 - 7.4e-09 35.6 0.1 1.4e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold PC4 PF02229.16 ETS81302.1 - 1.8e-23 81.9 0.2 3.2e-23 81.1 0.2 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) PXA PF02194.15 ETS81303.1 - 1.9e-32 112.7 1.0 3e-32 112.1 0.1 1.8 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 ETS81303.1 - 3.3e-22 79.2 0.7 1.3e-21 77.3 0.1 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 ETS81303.1 - 4.5e-05 23.4 0.0 0.00034 20.6 0.0 2.4 2 0 0 2 2 2 1 PX domain HsbA PF12296.8 ETS81303.1 - 0.71 10.3 3.8 1.3 9.4 0.7 2.8 3 0 0 3 3 3 0 Hydrophobic surface binding protein A Surface_antigen PF11054.8 ETS81305.1 - 0.0059 16.3 0.1 0.0077 15.9 0.1 1.1 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Glyco_hydro_16 PF00722.21 ETS81306.1 - 0.0015 18.1 0.0 0.0015 18.1 0.0 3.4 4 1 0 4 4 4 1 Glycosyl hydrolases family 16 bZIP_1 PF00170.21 ETS81308.1 - 2.2e-07 30.9 6.5 2.2e-07 30.9 6.5 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ETS81308.1 - 4.9e-05 23.3 4.9 4.9e-05 23.3 4.9 1.8 2 0 0 2 2 2 1 Basic region leucine zipper SHE3 PF17078.5 ETS81308.1 - 0.00018 21.3 0.4 0.00025 20.8 0.4 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 ETS81308.1 - 0.014 15.9 6.3 0.027 15.0 6.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF2514 PF10721.9 ETS81308.1 - 0.058 13.4 4.8 0.08 13.0 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DUF745 PF05335.13 ETS81308.1 - 0.16 11.7 4.6 0.18 11.5 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) TPR_12 PF13424.6 ETS81309.1 - 2.7e-09 37.2 2.2 0.0044 17.3 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 ETS81309.1 - 9.9e-08 31.5 0.3 0.083 13.0 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 ETS81309.1 - 1.4e-05 24.8 6.5 0.12 12.6 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 ETS81309.1 - 3.4e-05 23.5 5.5 0.63 10.0 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ETS81309.1 - 0.0032 18.2 4.6 3.3 8.8 0.0 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 ETS81309.1 - 0.0047 17.0 5.3 0.16 12.3 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 ETS81309.1 - 0.65 9.9 8.2 8.2 6.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 ETS81310.1 - 8.4e-12 45.1 0.1 9.3e-12 44.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-C2H2 PF00096.26 ETS81311.1 - 2.9e-05 24.3 30.0 0.15 12.6 6.4 6.3 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS81311.1 - 0.00085 20.0 32.8 0.04 14.8 4.2 6.5 5 1 0 5 5 5 3 C2H2-type zinc finger zf-BED PF02892.15 ETS81311.1 - 4.7 7.3 19.9 6.9 6.8 0.9 4.7 4 1 0 4 4 4 0 BED zinc finger zf-C2H2_4 PF13894.6 ETS81312.1 - 3.4e-06 27.4 9.5 0.0096 16.7 0.6 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ETS81312.1 - 0.00052 20.3 15.9 0.0088 16.5 0.5 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ETS81312.1 - 0.012 15.8 8.1 0.1 12.9 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 ETS81312.1 - 0.041 14.6 4.4 0.11 13.2 2.3 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 ETS81312.1 - 0.12 12.9 5.0 4.2 7.9 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-RAG1 PF10426.9 ETS81312.1 - 0.12 12.6 0.1 0.38 10.9 0.1 2.0 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain Sina PF03145.16 ETS81312.1 - 0.25 11.3 9.9 0.13 12.2 1.9 2.3 2 0 0 2 2 2 0 Seven in absentia protein family PBP1_TM PF14812.6 ETS81312.1 - 4.9 7.6 11.4 14 6.1 0.8 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal KAR9 PF08580.10 ETS81312.1 - 8.2 4.8 15.4 12 4.3 15.4 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Transpos_assoc PF13963.6 ETS81312.1 - 9.7 6.6 11.0 3.2 8.1 0.5 3.7 3 1 1 4 4 4 0 Transposase-associated domain Glyco_hydro_43 PF04616.14 ETS81313.1 - 0.015 14.6 1.6 0.036 13.4 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 ETS81313.1 - 0.04 13.5 0.0 0.09 12.3 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain DAO PF01266.24 ETS81314.1 - 5.8e-35 121.5 0.6 6.9e-35 121.3 0.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ETS81314.1 - 0.00027 20.3 0.0 0.00057 19.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 ETS81314.1 - 0.0006 19.8 0.5 0.082 12.9 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ETS81314.1 - 0.0056 16.9 0.3 0.015 15.6 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS81314.1 - 0.0065 15.8 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS81314.1 - 0.05 12.8 0.2 0.1 11.8 0.2 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS81314.1 - 0.058 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 ETS81314.1 - 0.09 12.0 0.2 0.34 10.1 0.1 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 ETS81314.1 - 0.11 12.5 0.0 18 5.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3328 PF11807.8 ETS81316.1 - 3.8e-21 75.9 4.4 9.1e-21 74.6 4.4 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) GAS2 PF02187.17 ETS81316.1 - 0.22 11.6 1.9 0.26 11.4 0.1 2.0 2 0 0 2 2 2 0 Growth-Arrest-Specific Protein 2 Domain Acetyltransf_1 PF00583.25 ETS81318.1 - 2.6e-06 27.7 0.0 4.4e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS81318.1 - 1e-05 25.9 0.0 1.8e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS81318.1 - 5.2e-05 23.2 0.0 8.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETS81318.1 - 0.016 15.3 0.9 0.056 13.5 0.6 2.0 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Pyr_redox_2 PF07992.14 ETS81319.1 - 1.3e-22 80.4 0.0 6.3e-21 74.9 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS81319.1 - 6.8e-09 34.9 0.1 5.4e-05 22.1 0.0 2.6 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 ETS81319.1 - 3e-07 30.5 0.0 0.027 14.5 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ETS81319.1 - 4.1e-06 26.9 0.0 1.1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS81319.1 - 5.3e-06 25.8 0.1 2e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 ETS81319.1 - 1.8e-05 24.5 0.0 5.1e-05 23.0 0.0 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS81319.1 - 7.8e-05 22.1 0.8 5.2 6.2 0.0 2.8 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ETS81319.1 - 0.00018 20.9 0.5 0.11 11.7 0.1 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 ETS81319.1 - 0.00041 19.7 0.1 0.00082 18.7 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 ETS81319.1 - 0.00053 19.2 4.8 0.0037 16.4 0.3 2.6 2 1 1 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 ETS81319.1 - 0.00062 19.1 0.0 0.0016 17.7 0.0 1.7 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 ETS81319.1 - 0.00073 18.9 0.1 0.0016 17.8 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 ETS81319.1 - 0.0013 19.3 0.3 0.063 13.8 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS81319.1 - 0.0042 16.2 0.3 0.013 14.5 0.2 1.8 1 1 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 ETS81319.1 - 0.0053 15.7 0.0 0.0073 15.2 0.0 1.1 1 0 0 1 1 1 1 Tryptophan halogenase IncFII_repA PF02387.15 ETS81319.1 - 0.013 14.7 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 IncFII RepA protein family FAD_oxidored PF12831.7 ETS81319.1 - 0.018 14.4 0.3 0.018 14.4 0.3 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 ETS81319.1 - 0.079 13.4 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding K_oxygenase PF13434.6 ETS81319.1 - 0.098 11.8 0.0 4.7 6.2 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 ETS81319.1 - 0.1 12.4 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mononeg_mRNAcap PF14318.6 ETS81319.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V MFS_1 PF07690.16 ETS81320.1 - 1.8e-37 129.1 53.3 1.8e-37 129.1 53.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sulfatase PF00884.23 ETS81321.1 - 3.1e-41 141.8 1.8 4.7e-41 141.2 1.8 1.2 1 0 0 1 1 1 1 Sulfatase DUF2330 PF10092.9 ETS81321.1 - 0.0019 17.3 0.0 0.0035 16.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2330) Sugar_tr PF00083.24 ETS81323.1 - 9.7e-71 238.9 22.9 1.1e-70 238.8 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS81323.1 - 2.9e-12 46.2 40.7 4.3e-12 45.6 33.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS81323.1 - 9.6e-07 27.7 16.5 0.0011 17.6 1.5 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 ETS81323.1 - 0.0044 15.9 4.3 0.0044 15.9 4.3 2.3 2 0 0 2 2 2 2 MFS_1 like family DUF2301 PF10063.9 ETS81323.1 - 1.2 9.6 6.9 6.8 7.1 0.4 2.9 3 0 0 3 3 3 0 Uncharacterized integral membrane protein (DUF2301) Peptidase_C14 PF00656.22 ETS81324.1 - 0.084 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Caspase domain Abhydrolase_1 PF00561.20 ETS81327.1 - 3.8e-11 43.1 0.4 6.6e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS81327.1 - 7.4e-11 43.1 1.5 7.4e-11 43.1 1.5 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS81327.1 - 0.00056 19.2 0.0 0.00077 18.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 ETS81327.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 ETS81327.1 - 0.01 16.0 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain RHH_1 PF01402.21 ETS81327.1 - 0.049 13.6 0.9 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family LIDHydrolase PF10230.9 ETS81327.1 - 0.079 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PLDc PF00614.22 ETS81328.1 - 4.7e-17 61.4 0.5 2e-07 30.9 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 ETS81328.1 - 8.1e-14 51.6 0.0 5.2e-07 29.6 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PX PF00787.24 ETS81328.1 - 1.1e-07 31.8 0.0 9.9e-07 28.7 0.0 2.7 2 1 0 2 2 2 1 PX domain Lzipper-MIP1 PF14389.6 ETS81329.1 - 0.00041 20.6 25.4 0.094 13.0 0.2 4.4 3 1 1 4 4 4 2 Leucine-zipper of ternary complex factor MIP1 MAD PF05557.13 ETS81329.1 - 0.0024 16.3 27.3 0.0024 16.3 27.3 4.2 4 1 0 4 4 4 2 Mitotic checkpoint protein HMMR_N PF15905.5 ETS81329.1 - 0.0033 17.0 2.9 0.0033 17.0 2.9 4.5 4 1 0 4 4 4 1 Hyaluronan mediated motility receptor N-terminal ATG16 PF08614.11 ETS81329.1 - 0.009 16.3 10.0 0.009 16.3 10.0 5.6 2 2 3 5 5 5 3 Autophagy protein 16 (ATG16) FlxA PF14282.6 ETS81329.1 - 0.0094 15.9 3.9 0.0094 15.9 3.9 6.8 2 1 4 6 6 6 1 FlxA-like protein ADIP PF11559.8 ETS81329.1 - 0.019 15.0 11.4 0.019 15.0 11.4 6.0 5 2 1 6 6 6 0 Afadin- and alpha -actinin-Binding HOOK PF05622.12 ETS81329.1 - 0.27 9.3 57.6 0.056 11.6 25.1 3.0 1 1 1 2 2 2 0 HOOK protein Spc7 PF08317.11 ETS81329.1 - 0.82 8.5 62.9 0.035 13.0 9.0 4.1 4 1 0 4 4 4 0 Spc7 kinetochore protein APC_N_CC PF16689.5 ETS81329.1 - 1.7 8.7 12.2 0.82 9.8 1.2 4.1 2 1 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain Shugoshin_N PF07558.11 ETS81329.1 - 1.9 8.4 21.7 6.1 6.8 0.1 6.3 7 0 0 7 7 7 0 Shugoshin N-terminal coiled-coil region PGP_phosphatase PF09419.10 ETS81330.1 - 0.039 13.6 0.0 0.041 13.5 0.0 1.3 1 1 0 1 1 1 0 Mitochondrial PGP phosphatase Hydrolase PF00702.26 ETS81330.1 - 0.21 11.9 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ETS81331.1 - 3.6e-07 30.5 0.0 0.025 14.7 0.2 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ETS81331.1 - 6.8e-05 22.8 0.8 9.8e-05 22.3 0.8 1.5 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ETS81331.1 - 0.037 14.3 0.0 0.69 10.2 0.5 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 ETS81332.1 - 2e-64 217.5 0.0 2.6e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS81332.1 - 1e-38 133.1 0.0 1.4e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ETS81332.1 - 0.00011 21.2 0.0 0.00016 20.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ETS81332.1 - 0.0044 16.4 0.0 0.0089 15.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ETS81332.1 - 0.015 14.3 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 ETS81332.1 - 0.042 12.9 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 ETS81332.1 - 0.16 11.6 0.2 1.5 8.4 0.1 2.0 2 0 0 2 2 2 0 RIO1 family SH2_2 PF14633.6 ETS81333.1 - 9.5e-80 267.0 0.1 9.5e-80 267.0 0.1 2.3 2 0 0 2 2 2 1 SH2 domain HTH_44 PF14641.6 ETS81333.1 - 4.9e-39 133.3 2.4 1.3e-38 131.9 2.4 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 ETS81333.1 - 7.4e-31 106.6 0.0 1.9e-30 105.3 0.0 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif YqgF PF14639.6 ETS81333.1 - 1.7e-30 105.8 0.0 5.8e-30 104.1 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 ETS81333.1 - 2.2e-20 73.0 29.1 2.2e-20 73.0 29.1 6.9 3 1 3 6 6 6 1 Acidic N-terminal SPT6 S1 PF00575.23 ETS81333.1 - 1.1e-06 28.8 1.0 3.4e-06 27.3 0.4 2.1 2 0 0 2 2 2 1 S1 RNA binding domain SH2 PF00017.24 ETS81333.1 - 6.6e-06 26.1 0.0 1.9e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 ETS81333.1 - 1.4e-05 25.9 2.6 1.4e-05 25.9 2.6 4.3 3 1 0 3 3 3 1 HHH domain HHH_3 PF12836.7 ETS81333.1 - 0.00076 19.7 0.0 0.0036 17.5 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif Oxysterol_BP PF01237.18 ETS81334.1 - 5.1e-113 377.7 0.0 9.1e-113 376.9 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 ETS81334.1 - 4.7e-38 129.3 0.9 1.6e-37 127.6 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 ETS81334.1 - 1.5e-07 31.9 0.0 3.2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 PH domain DDHD PF02862.17 ETS81335.1 - 6e-63 213.0 0.0 6e-63 213.0 0.0 3.2 2 1 0 2 2 2 1 DDHD domain AAR2 PF05282.11 ETS81335.1 - 9.3e-05 22.0 1.4 0.00015 21.3 0.1 2.0 2 0 0 2 2 2 1 AAR2 protein LIDHydrolase PF10230.9 ETS81335.1 - 0.018 14.6 3.0 0.082 12.4 0.0 2.9 3 0 0 3 3 3 0 Lipid-droplet associated hydrolase WWE PF02825.20 ETS81335.1 - 0.11 13.1 0.2 4.1 8.1 0.0 2.8 2 0 0 2 2 2 0 WWE domain zf-CCHC PF00098.23 ETS81336.1 - 3.6e-55 181.7 65.9 8.3e-10 38.3 3.7 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 ETS81336.1 - 2.3e-12 46.4 43.2 0.019 14.7 0.5 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 ETS81336.1 - 1.3e-07 31.4 54.3 0.052 13.5 0.4 7.1 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 ETS81336.1 - 3.4e-07 29.9 43.4 0.13 12.0 0.7 7.1 6 1 1 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 ETS81336.1 - 0.0051 16.6 2.6 0.0051 16.6 2.6 7.1 7 0 0 7 7 7 4 Zinc knuckle zf-CCHC_6 PF15288.6 ETS81336.1 - 0.011 15.5 52.0 0.087 12.7 1.2 7.0 5 2 2 7 7 7 0 Zinc knuckle SAE2 PF08573.10 ETS81337.1 - 1.2e-21 77.9 0.0 1.2e-21 77.9 0.0 3.3 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus CENP-Q PF13094.6 ETS81337.1 - 0.0045 17.2 5.6 0.0045 17.2 5.6 2.9 2 1 1 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF641 PF04859.12 ETS81337.1 - 0.22 11.8 8.7 0.066 13.5 2.3 2.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) BLOC1_2 PF10046.9 ETS81337.1 - 1.2 9.5 7.1 1.4 9.2 1.6 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0184 PF03670.13 ETS81337.1 - 2 8.8 4.2 2.2 8.7 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Atg14 PF10186.9 ETS81337.1 - 2.3 7.2 15.7 0.077 12.1 2.0 3.2 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sipho_Gp157 PF05565.11 ETS81337.1 - 2.3 8.2 11.2 0.16 12.0 2.1 2.4 2 0 0 2 2 2 0 Siphovirus Gp157 bZIP_1 PF00170.21 ETS81337.1 - 2.9 8.1 18.8 0.048 13.8 2.3 3.7 2 1 1 3 3 3 0 bZIP transcription factor Cep57_CLD_2 PF14197.6 ETS81337.1 - 4 7.6 11.8 2.6 8.2 6.1 3.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF2570 PF10828.8 ETS81337.1 - 7.9 6.3 12.2 17 5.3 3.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) Rootletin PF15035.6 ETS81337.1 - 8.6 6.3 19.5 0.66 10.0 1.1 3.1 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion HALZ PF02183.18 ETS81337.1 - 9 6.6 11.2 8.6 6.7 1.4 3.4 3 1 0 3 3 3 0 Homeobox associated leucine zipper UCH PF00443.29 ETS81338.1 - 1.7e-45 155.6 0.0 2.8e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ETS81338.1 - 1.3e-09 38.2 0.2 1.5e-08 34.6 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MFS_1 PF07690.16 ETS81339.1 - 7.1e-29 100.8 32.0 9.6e-29 100.4 32.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS81339.1 - 7.3e-06 25.5 3.0 7.3e-06 25.5 3.0 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Aminotran_1_2 PF00155.21 ETS81340.1 - 1e-15 57.8 0.0 2e-15 56.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ETS81340.1 - 0.0032 16.3 0.0 0.0065 15.3 0.0 1.4 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase ICL PF00463.21 ETS81341.1 - 1.2e-111 373.8 0.2 1.4e-111 373.6 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 ETS81341.1 - 8.4e-08 32.0 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase KH_10 PF17905.1 ETS81341.1 - 0.074 13.5 0.1 3.9 8.0 0.0 2.3 2 0 0 2 2 2 0 GLD-3 KH domain 5 HA PF03457.14 ETS81341.1 - 0.38 11.1 1.7 0.97 9.8 0.0 2.3 2 0 0 2 2 2 0 Helicase associated domain NPP1 PF05630.11 ETS81343.1 - 3.5e-63 213.3 0.0 4e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Aa_trans PF01490.18 ETS81344.1 - 3.4e-19 68.8 17.4 4.2e-19 68.5 17.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GWT1 PF06423.12 ETS81344.1 - 0.1 12.7 10.5 0.04 14.0 2.7 2.9 1 1 1 2 2 2 0 GWT1 GNVR PF13807.6 ETS81344.1 - 0.16 11.9 0.0 0.57 10.1 0.0 2.0 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase Aa_trans PF01490.18 ETS81345.1 - 0.038 12.7 0.1 0.042 12.6 0.1 1.0 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein MARVEL PF01284.23 ETS81346.1 - 3.8e-19 69.1 17.6 4.9e-19 68.8 17.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF3687 PF12459.8 ETS81346.1 - 0.063 12.8 0.8 4.1 7.0 0.2 2.5 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein ABC2_membrane_5 PF13346.6 ETS81346.1 - 0.14 11.7 10.7 0.18 11.3 10.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein YpzI PF14140.6 ETS81347.1 - 9 6.2 8.6 31 4.4 0.0 4.0 4 0 0 4 4 4 0 YpzI-like protein HMGL-like PF00682.19 ETS81348.1 - 5.6e-80 268.7 0.9 8.3e-80 268.1 0.9 1.2 1 0 0 1 1 1 1 HMGL-like AMP-binding PF00501.28 ETS81349.1 - 1e-96 324.1 0.0 1.7e-96 323.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 ETS81349.1 - 1.1e-84 284.0 0.0 1.9e-84 283.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ETS81349.1 - 4.1e-55 186.5 0.1 5.4e-52 176.3 0.1 2.8 2 0 0 2 2 2 2 KR domain NAD_binding_4 PF07993.12 ETS81349.1 - 1.8e-52 178.1 0.1 1.5e-50 171.8 0.0 2.9 2 1 0 2 2 2 1 Male sterility protein Acyl_transf_1 PF00698.21 ETS81349.1 - 7.8e-49 166.9 0.1 1.3e-48 166.1 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ETS81349.1 - 2.8e-41 140.2 0.9 6.4e-41 139.1 0.9 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 ETS81349.1 - 2.4e-25 88.7 0.1 6.1e-12 45.7 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 ETS81349.1 - 9.2e-15 55.1 0.0 2.2e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 ETS81349.1 - 5.8e-14 52.1 0.4 8.7e-12 45.0 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 ETS81349.1 - 5.4e-08 32.5 1.0 3.5e-07 29.9 0.0 2.7 3 0 0 3 3 3 1 short chain dehydrogenase AMP-binding_C PF13193.6 ETS81349.1 - 7.1e-08 33.3 0.0 1.6e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 ETS81349.1 - 8.3e-08 31.6 0.0 0.006 15.6 0.0 2.5 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ETS81349.1 - 2.3e-07 30.6 0.0 0.0024 17.4 0.0 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 ETS81349.1 - 1.5e-06 27.8 0.1 3.7e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.15 ETS81349.1 - 0.0011 18.1 0.1 0.07 12.3 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ETS81349.1 - 0.025 14.2 1.6 0.44 10.1 0.1 3.0 3 0 0 3 3 3 0 NmrA-like family RmlD_sub_bind PF04321.17 ETS81349.1 - 0.44 9.6 1.3 2.1 7.4 0.2 2.5 2 1 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.13 ETS81350.1 - 2.8e-08 33.6 0.0 1.6e-07 31.1 0.0 1.9 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 ETS81350.1 - 0.00094 19.1 0.0 0.0029 17.5 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS81350.1 - 0.0046 16.4 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family IRF-2BP1_2 PF11261.8 ETS81350.1 - 0.15 11.6 0.2 8.5 6.0 0.0 2.8 2 0 0 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger PhyH PF05721.13 ETS81351.1 - 1.1e-13 51.9 0.0 1.5e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AA_permease_2 PF13520.6 ETS81352.1 - 2.2e-32 112.5 44.7 2.8e-32 112.1 44.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS81352.1 - 6.2e-12 44.9 38.9 8.2e-12 44.5 38.9 1.1 1 0 0 1 1 1 1 Amino acid permease YrhC PF14143.6 ETS81352.1 - 3.9 7.6 6.6 1.7 8.8 1.6 2.9 2 0 0 2 2 2 0 YrhC-like protein DIOX_N PF14226.6 ETS81353.1 - 2e-22 80.2 0.0 3.3e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS81353.1 - 2.6e-13 50.3 0.0 3.9e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily P5CR_dimer PF14748.6 ETS81354.1 - 5.3e-25 87.7 1.1 9.5e-25 86.8 1.1 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 ETS81354.1 - 2.8e-05 24.6 0.0 9.4e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 ETS81355.1 - 1.8e-46 159.3 0.1 2.1e-46 159.1 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS81355.1 - 0.00025 20.4 0.1 0.45 9.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS81355.1 - 0.00095 19.2 1.9 0.37 10.8 0.1 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ETS81355.1 - 0.0014 17.9 0.6 0.063 12.5 0.1 2.8 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ETS81355.1 - 0.0029 17.0 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 ETS81355.1 - 0.0043 16.2 0.1 1.8 7.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 ETS81355.1 - 0.0099 15.1 0.0 0.61 9.3 0.0 2.5 2 0 0 2 2 2 1 Thi4 family ALG3 PF05208.13 ETS81355.1 - 0.016 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 ALG3 protein Lycopene_cycl PF05834.12 ETS81355.1 - 0.028 13.5 0.2 0.3 10.1 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 ETS81355.1 - 0.031 13.0 0.0 1.2 7.7 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein Carb_kinase PF01256.17 ETS81355.1 - 0.038 13.5 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate kinase MFS_1 PF07690.16 ETS81356.1 - 3e-20 72.5 72.4 9.5e-15 54.4 38.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 ETS81357.1 - 7.8e-06 25.9 9.6 1.2e-05 25.3 9.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ArAE_2_N PF10337.9 ETS81358.1 - 1.2e-86 291.7 8.0 1.9e-86 291.0 8.0 1.2 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 ETS81358.1 - 1.8e-31 109.7 0.0 3.1e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 ETS81358.1 - 2.3e-07 31.0 13.9 2.3e-07 31.0 13.9 3.4 2 1 1 3 3 3 1 Fusaric acid resistance protein-like p450 PF00067.22 ETS81359.1 - 4.7e-72 243.2 0.0 6.2e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RasGAP_C PF03836.15 ETS81359.1 - 0.1 12.7 0.8 16 5.7 0.1 2.4 2 0 0 2 2 2 0 RasGAP C-terminus Acyl-CoA_dh_1 PF00441.24 ETS81360.1 - 2.4e-14 53.8 0.1 5.7e-13 49.3 0.1 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 ETS81360.1 - 4.2e-11 43.0 0.0 2e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 ETS81360.1 - 4.5e-09 36.4 0.0 1.6e-08 34.6 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ETS81360.1 - 0.0051 17.1 0.0 0.05 13.9 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain GAF_2 PF13185.6 ETS81361.1 - 5.7e-06 26.7 0.1 1.7e-05 25.1 0.1 1.8 1 1 0 1 1 1 1 GAF domain GAF PF01590.26 ETS81361.1 - 0.0096 16.6 0.0 0.016 15.8 0.0 1.3 1 1 0 1 1 1 1 GAF domain CN_hydrolase PF00795.22 ETS81362.1 - 8.7e-58 195.7 0.0 1e-57 195.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Spermine_synth PF01564.17 ETS81363.1 - 2.4e-71 239.1 0.0 3.5e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 ETS81363.1 - 8.1e-25 86.5 0.3 1.5e-24 85.6 0.3 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 ETS81363.1 - 0.00029 21.5 0.0 0.00054 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.16 ETS81363.1 - 0.0068 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_2 PF00891.18 ETS81363.1 - 0.047 13.0 0.1 0.12 11.7 0.1 1.7 1 1 1 2 2 2 0 O-methyltransferase domain Methyltransf_18 PF12847.7 ETS81363.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 ETS81363.1 - 0.14 12.9 0.1 0.36 11.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain G-alpha PF00503.20 ETS81364.1 - 2.5e-107 359.1 0.8 3e-107 358.8 0.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ETS81364.1 - 2.2e-13 50.0 0.4 2.1e-08 33.8 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ETS81364.1 - 0.00021 20.7 2.0 0.011 15.2 0.0 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_15 PF13175.6 ETS81364.1 - 0.023 14.4 0.1 0.031 14.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 ETS81364.1 - 0.041 14.1 0.2 6.6 7.0 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 ETS81364.1 - 0.048 13.2 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 ETS81364.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 ETS81364.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_hydro_3_C PF01915.22 ETS81365.1 - 1.5e-42 145.9 0.0 3.6e-42 144.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS81365.1 - 3.9e-39 134.9 0.0 7.1e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS81365.1 - 1.1e-20 73.5 0.1 2.1e-20 72.6 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Fungal_trans PF04082.18 ETS81366.1 - 3.3e-10 39.4 0.0 5.2e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS81366.1 - 3.4e-09 36.7 9.8 6.6e-09 35.8 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ChapFlgA_N PF17656.1 ETS81366.1 - 0.11 12.7 0.0 0.59 10.3 0.0 2.3 2 0 0 2 2 2 0 FlgA N-terminal domain SporV_AA PF12164.8 ETS81367.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AA p450 PF00067.22 ETS81368.1 - 2.6e-27 95.7 0.0 3e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.6 ETS81369.1 - 5e-27 95.0 0.6 6.2e-27 94.7 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS81369.1 - 5.8e-20 71.6 0.1 6.9e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS81369.1 - 6.9e-05 22.8 0.1 0.0001 22.3 0.1 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 ETS81369.1 - 0.0085 16.2 0.1 0.015 15.4 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FliC_SP PF12613.8 ETS81369.1 - 2.6 8.6 6.5 0.44 11.1 2.3 2.0 2 0 0 2 2 2 0 Flagellin structural protein DUF1373 PF07117.11 ETS81370.1 - 0.012 15.6 3.6 0.012 15.6 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1373) zinc_ribbon_4 PF13717.6 ETS81370.1 - 0.11 12.4 0.4 0.22 11.5 0.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain HeLo PF14479.6 ETS81372.1 - 8e-24 84.6 2.2 1.6e-23 83.6 0.1 2.2 1 1 1 2 2 2 1 Prion-inhibition and propagation DUF601 PF04642.12 ETS81372.1 - 0.022 14.3 0.9 0.041 13.4 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF601 ADIP PF11559.8 ETS81374.1 - 2.2e-39 135.0 3.4 2.2e-39 135.0 3.4 3.1 5 0 0 5 5 5 1 Afadin- and alpha -actinin-Binding Rootletin PF15035.6 ETS81374.1 - 0.0092 16.0 3.0 0.0092 16.0 3.0 2.5 3 0 0 3 3 3 1 Ciliary rootlet component, centrosome cohesion DUF484 PF04340.12 ETS81374.1 - 0.03 14.0 4.1 0.093 12.4 4.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF484 TTKRSYEDQ PF10212.9 ETS81374.1 - 0.15 11.1 1.6 0.28 10.1 1.6 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Golgin_A5 PF09787.9 ETS81374.1 - 0.41 10.1 7.9 0.03 13.8 1.7 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF641 PF04859.12 ETS81374.1 - 2.5 8.5 10.5 1.5 9.2 2.1 4.1 4 1 1 5 5 5 0 Plant protein of unknown function (DUF641) DivIVA PF05103.13 ETS81374.1 - 3.5 7.7 6.2 1.3 9.1 2.1 2.4 2 0 0 2 2 2 0 DivIVA protein TMF_DNA_bd PF12329.8 ETS81374.1 - 6.6 6.8 13.3 0.64 10.0 0.9 3.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Amino_oxidase PF01593.24 ETS81375.1 - 8.6e-40 137.4 0.0 4.3e-39 135.1 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ETS81375.1 - 1.4e-14 54.0 0.0 2.7e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS81375.1 - 1.2e-06 28.0 0.1 6.8e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS81375.1 - 3e-05 24.1 0.3 0.071 13.1 0.2 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 ETS81375.1 - 0.00034 21.1 1.5 0.0032 18.0 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS81375.1 - 0.00041 19.2 0.2 0.039 12.7 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 ETS81375.1 - 0.0033 17.0 5.0 0.011 15.3 0.9 3.1 3 1 1 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS81375.1 - 0.0094 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ETS81375.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 ETS81375.1 - 0.069 12.2 0.1 0.4 9.7 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein GramPos_pilinD1 PF16555.5 ETS81376.1 - 0.19 11.9 0.1 0.28 11.4 0.1 1.2 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain ATG2_CAD PF13329.6 ETS81377.1 - 2e-46 157.5 0.2 5.7e-46 156.0 0.2 1.9 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 ETS81377.1 - 2.5e-30 104.6 0.3 2.6e-29 101.4 0.0 2.9 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 ETS81377.1 - 0.00022 21.3 0.1 0.002 18.2 0.0 2.6 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 ETS81377.1 - 0.0071 16.1 0.1 0.017 14.9 0.1 1.5 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal adh_short_C2 PF13561.6 ETS81378.1 - 1.2e-43 149.4 0.0 1.4e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS81378.1 - 9.3e-41 139.4 0.0 1.2e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS81378.1 - 4.7e-10 39.7 0.5 1.3e-09 38.3 0.5 1.6 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 ETS81378.1 - 0.00011 21.7 0.0 0.00019 20.9 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ETS81378.1 - 0.0054 16.2 0.0 0.03 13.8 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS81378.1 - 0.0065 16.4 0.0 0.013 15.4 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ETS81378.1 - 0.072 12.2 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 ETS81378.1 - 0.15 12.1 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3459 PF11941.8 ETS81378.1 - 0.15 12.4 0.0 1.1 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3459) Glyco_transf_8 PF01501.20 ETS81379.1 - 1.8e-09 37.6 0.0 9.4e-09 35.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Alpha-amylase PF00128.24 ETS81380.1 - 2.9e-08 33.7 0.0 7.7e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Mito_carr PF00153.27 ETS81382.1 - 4.6e-52 173.9 0.2 1.1e-17 63.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L22e PF01776.17 ETS81383.1 - 5.5e-44 149.0 2.1 6.9e-44 148.7 2.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family START PF01852.19 ETS81383.1 - 0.15 11.5 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 START domain Aldedh PF00171.22 ETS81384.1 - 8.6e-73 245.4 0.0 1e-72 245.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ECR1_N PF14382.6 ETS81387.1 - 2.9e-14 52.5 0.2 5.7e-14 51.6 0.2 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 ETS81387.1 - 0.00021 21.6 0.1 0.00045 20.5 0.1 1.6 1 0 0 1 1 1 1 KH domain Pex24p PF06398.11 ETS81388.1 - 4e-94 315.6 0.1 5.1e-94 315.3 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 ETS81388.1 - 0.0008 17.9 5.7 0.0023 16.4 1.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) DUF639 PF04842.12 ETS81388.1 - 0.33 10.3 1.4 0.75 9.2 0.2 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) PRT_C PF08372.10 ETS81388.1 - 1.2 8.8 3.9 2 8.2 0.5 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal polyprenyl_synt PF00348.17 ETS81389.1 - 7.8e-66 221.7 0.0 1.6e-65 220.7 0.0 1.5 2 0 0 2 2 2 1 Polyprenyl synthetase CDC14 PF08045.11 ETS81390.1 - 1.7e-122 408.0 0.2 1.9e-122 407.8 0.2 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component SKG6 PF08693.10 ETS81391.1 - 0.011 15.1 1.5 0.02 14.3 1.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain STAT1_TAZ2bind PF12162.8 ETS81391.1 - 0.75 9.4 2.2 2 8.1 1.1 2.1 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain HD PF01966.22 ETS81392.1 - 1e-05 25.7 0.1 6.2e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 HD domain HDOD PF08668.12 ETS81392.1 - 0.15 11.5 0.1 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 HDOD domain AMPK1_CBM PF16561.5 ETS81393.1 - 4.6e-05 23.6 0.0 8.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase TraG-D_C PF12696.7 ETS81393.1 - 5.5 7.0 7.7 10 6.1 0.1 2.7 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG VIT1 PF01988.19 ETS81394.1 - 0.022 14.6 0.2 0.028 14.3 0.2 1.2 1 0 0 1 1 1 0 VIT family Hormone_3 PF00159.18 ETS81394.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide DUF2207 PF09972.9 ETS81394.1 - 0.14 10.9 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_S10 PF00450.22 ETS81394.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase DUF4924 PF16271.5 ETS81396.1 - 0.057 13.4 0.0 0.058 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) Amidohydro_2 PF04909.14 ETS81397.1 - 1.4e-25 90.7 0.0 5.2e-25 88.8 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase Glyoxalase PF00903.25 ETS81398.1 - 0.00097 19.3 0.0 0.0019 18.4 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SUR7 PF06687.12 ETS81399.1 - 4.7e-36 124.4 15.7 5.6e-36 124.2 15.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family Cadherin_C_2 PF16492.5 ETS81399.1 - 0.067 13.9 0.0 8.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal ERGIC_N PF13850.6 ETS81399.1 - 0.074 13.4 0.3 0.41 11.0 0.1 2.1 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Endomucin PF07010.12 ETS81400.1 - 0.18 11.7 16.0 0.26 11.2 16.0 1.2 1 0 0 1 1 1 0 Endomucin DWNN PF08783.11 ETS81401.1 - 1.1e-29 102.5 0.0 1.9e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 ETS81401.1 - 1.1e-07 31.6 7.1 4e-07 29.7 6.3 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 ETS81401.1 - 0.00018 21.4 0.6 0.00036 20.5 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-RING_6 PF14835.6 ETS81401.1 - 0.00078 19.3 1.4 0.0015 18.4 1.4 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 ETS81401.1 - 0.0029 17.4 8.3 0.0059 16.4 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 ETS81401.1 - 0.0036 17.5 0.2 0.012 15.8 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-RING_2 PF13639.6 ETS81401.1 - 0.0065 16.8 6.8 0.015 15.6 6.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 ETS81401.1 - 0.019 14.8 4.6 0.039 13.7 4.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 ETS81401.1 - 0.33 11.0 12.9 0.023 14.7 7.5 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 ETS81401.1 - 0.38 10.6 8.4 0.79 9.6 8.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 ETS81401.1 - 0.48 10.3 5.1 1.2 9.0 5.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE_2 PF02318.16 ETS81401.1 - 1.2 9.4 7.4 0.055 13.7 1.0 2.1 3 0 0 3 3 2 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.6 ETS81401.1 - 4.6 7.5 13.8 0.39 10.9 8.7 1.9 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING THOC2_N PF16134.5 ETS81401.1 - 6.6 5.2 7.4 14 4.2 3.9 2.2 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus zf-C3HC4_3 PF13920.6 ETS81401.1 - 7 6.6 10.2 0.41 10.6 4.3 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ArsA_ATPase PF02374.15 ETS81402.1 - 9.3e-111 369.9 0.0 1.1e-110 369.7 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 ETS81402.1 - 3.4e-13 49.9 0.4 1.3e-11 44.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 ETS81402.1 - 3.2e-12 46.6 0.0 5.1e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 ETS81402.1 - 5.3e-06 26.1 0.0 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 ETS81402.1 - 1.3e-05 24.8 0.3 0.00019 21.0 0.1 2.3 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 ETS81402.1 - 4e-05 23.2 0.0 9.4e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 ETS81402.1 - 4e-05 23.3 0.1 0.0014 18.3 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain DUF5131 PF07505.11 ETS81402.1 - 0.027 13.9 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF5131) AAA_25 PF13481.6 ETS81402.1 - 0.078 12.5 0.0 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ETS81402.1 - 0.079 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 ETS81402.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 ETS81402.1 - 0.13 12.8 0.1 0.35 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 ETS81402.1 - 0.17 11.3 0.1 0.49 9.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein DPBB_1 PF03330.18 ETS81403.1 - 3e-05 24.2 0.0 3.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ETS81403.1 - 0.0015 18.4 0.1 0.0021 17.9 0.1 1.3 1 0 0 1 1 1 1 Barwin family DUF1866 PF08952.11 ETS81403.1 - 0.09 12.6 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) GCV_T_C PF08669.11 ETS81403.1 - 0.13 12.2 0.1 0.32 11.0 0.0 1.6 2 0 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain Transthyretin PF00576.21 ETS81405.1 - 4.5e-38 130.3 0.2 6.8e-38 129.7 0.2 1.3 1 1 0 1 1 1 1 HIUase/Transthyretin family ADH_zinc_N PF00107.26 ETS81406.1 - 2e-21 76.3 0.1 3.2e-21 75.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS81406.1 - 4.7e-14 53.6 0.1 1.1e-13 52.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS81406.1 - 1.9e-09 37.3 0.1 2e-08 34.1 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ETS81406.1 - 0.00076 19.3 0.1 0.0015 18.4 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase adh_short PF00106.25 ETS81406.1 - 0.0074 15.8 0.9 0.014 14.9 0.6 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Translin PF01997.16 ETS81407.1 - 2.6e-45 155.0 0.0 3e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Translin family Endotoxin_C2 PF18449.1 ETS81407.1 - 0.0018 18.6 0.2 0.0053 17.1 0.1 1.9 2 0 0 2 2 2 1 Delta endotoxin DASH_Duo1 PF08651.10 ETS81407.1 - 0.063 13.1 0.2 0.27 11.1 0.1 2.1 2 0 0 2 2 2 0 DASH complex subunit Duo1 PIG-F PF06699.11 ETS81408.1 - 9.2e-66 221.4 4.7 1.1e-65 221.2 4.7 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Beta-lactamase PF00144.24 ETS81409.1 - 2.7e-47 161.6 0.1 3.3e-47 161.3 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 ETS81409.1 - 0.00077 19.0 0.0 0.0025 17.3 0.0 1.8 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase PhyH PF05721.13 ETS81411.1 - 3.4e-11 43.8 0.0 4.6e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) IFRD PF05004.13 ETS81413.1 - 4.1e-77 259.3 5.3 5.8e-77 258.8 5.3 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Arg_decarbox_C PF17944.1 ETS81413.1 - 0.012 16.2 0.2 0.012 16.2 0.2 2.5 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension Apolipoprotein PF01442.18 ETS81413.1 - 0.07 13.0 4.3 0.15 11.9 4.3 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain FHA PF00498.26 ETS81414.1 - 1.9e-06 28.1 0.0 4.9e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 FHA domain DUF2729 PF10870.8 ETS81414.1 - 0.54 10.2 4.2 1.9 8.4 4.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) PGA2 PF07543.12 ETS81415.1 - 0.39 10.7 2.9 0.74 9.8 2.9 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 SIS PF01380.22 ETS81417.1 - 8.2e-13 48.4 0.2 3e-12 46.5 0.2 2.0 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.6 ETS81417.1 - 0.044 13.8 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 SIS domain YadA_anchor PF03895.15 ETS81417.1 - 0.073 13.2 0.9 0.17 12.0 0.9 1.6 1 0 0 1 1 1 0 YadA-like membrane anchor domain L_HMGIC_fpl PF10242.9 ETS81418.1 - 2.7e-07 31.0 2.7 4e-06 27.2 2.7 2.0 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 ETS81418.1 - 0.0001 22.2 6.0 0.00021 21.2 6.0 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 ETS81418.1 - 0.00064 19.5 13.7 0.013 15.3 0.0 2.7 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 ETS81418.1 - 0.14 12.1 9.9 0.73 9.8 9.9 2.2 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF2373 PF10180.9 ETS81419.1 - 2.7e-21 75.2 0.2 5e-21 74.3 0.2 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.26 ETS81420.1 - 5.2e-49 166.3 0.0 7.2e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ETS81420.1 - 3e-12 46.0 0.2 5.9e-12 45.0 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ank_2 PF12796.7 ETS81422.1 - 0.0024 18.4 0.1 0.017 15.7 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) zf-RING_2 PF13639.6 ETS81422.1 - 0.0035 17.6 5.6 0.0098 16.2 5.6 1.8 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ETS81422.1 - 0.045 13.8 2.1 0.08 13.0 1.3 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 ETS81422.1 - 0.078 13.1 2.2 0.2 11.8 2.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ank_3 PF13606.6 ETS81422.1 - 0.14 12.8 0.0 4.2 8.2 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat zf-RING_4 PF14570.6 ETS81422.1 - 1.9 8.3 5.7 7 6.5 5.7 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Uds1 PF15456.6 ETS81423.1 - 7.7e-32 110.2 8.4 7.7e-32 110.2 8.4 2.9 4 0 0 4 4 4 1 Up-regulated During Septation Cnn_1N PF07989.11 ETS81423.1 - 0.3 11.3 2.8 5.7 7.2 0.0 2.9 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Peptidase_M1 PF01433.20 ETS81424.1 - 2e-42 145.2 0.3 2.9e-42 144.7 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 ETS81424.1 - 1.6e-30 106.7 0.0 2.6e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Leuk-A4-hydro_C PF09127.11 ETS81424.1 - 7e-29 100.2 0.0 1.8e-28 98.9 0.0 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Pet127 PF08634.10 ETS81424.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial protein Pet127 Peptidase_M61 PF05299.12 ETS81424.1 - 0.59 10.5 2.9 17 5.9 2.9 2.7 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Glyco_hydro_6 PF01341.17 ETS81425.1 - 4.6e-98 328.7 2.0 6.1e-98 328.3 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 OST3_OST6 PF04756.13 ETS81426.1 - 2e-101 339.2 0.0 2.4e-101 339.0 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Acyl_transf_3 PF01757.22 ETS81426.1 - 0.011 14.8 2.4 0.016 14.3 2.4 1.2 1 0 0 1 1 1 0 Acyltransferase family DUF3792 PF12670.7 ETS81426.1 - 0.26 11.5 4.7 1.2 9.3 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) NPV_P10 PF05531.12 ETS81427.1 - 0.029 14.8 1.1 0.029 14.8 1.1 5.4 3 2 3 6 6 6 0 Nucleopolyhedrovirus P10 protein FtsJ PF01728.19 ETS81428.1 - 6.3e-57 192.5 0.0 7.7e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 ETS81428.1 - 0.0005 19.9 0.0 0.001 19.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS81428.1 - 0.14 12.9 0.0 0.87 10.3 0.0 2.3 2 1 1 3 3 3 0 Methyltransferase domain MFS_1 PF07690.16 ETS81429.1 - 2e-21 76.3 27.2 6.5e-21 74.6 27.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS81429.1 - 7.9e-06 24.6 0.9 7.9e-06 24.6 0.9 2.6 2 1 1 3 3 3 2 Fungal trichothecene efflux pump (TRI12) DUF2070 PF09843.9 ETS81429.1 - 7 4.8 10.3 13 3.9 10.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MFS_1 PF07690.16 ETS81430.1 - 3.7e-09 36.0 8.2 3.7e-09 36.0 8.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS81430.1 - 0.0064 15.4 0.7 0.008 15.1 0.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 ETS81430.1 - 0.036 12.6 6.5 0.0091 14.6 3.1 1.7 1 1 1 2 2 2 0 MFS/sugar transport protein UPF0239 PF06783.11 ETS81431.1 - 0.15 12.3 0.7 7.4 6.8 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0239) DUF4834 PF16118.5 ETS81431.1 - 0.19 12.7 0.3 2.6 9.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Glyco_hydro_3_C PF01915.22 ETS81432.1 - 9.1e-45 153.1 0.0 1.6e-44 152.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS81432.1 - 1.1e-35 123.6 0.0 2.4e-34 119.1 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS81432.1 - 4.8e-20 71.5 0.0 9.1e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain LssY_C PF14067.6 ETS81432.1 - 0.033 13.7 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 LssY C-terminus Acyl-CoA_dh_1 PF00441.24 ETS81433.1 - 2.4e-35 121.9 0.2 3.7e-35 121.3 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 ETS81433.1 - 7e-20 71.0 0.1 1.6e-19 69.8 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 ETS81433.1 - 4.7e-15 55.6 0.3 8.1e-15 54.8 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ETS81433.1 - 9.9e-07 29.4 0.1 3.1e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ETS81433.1 - 0.0002 21.6 0.0 0.00045 20.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF4255 PF14065.6 ETS81433.1 - 0.19 11.4 0.0 0.84 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4255) LIP PF03583.14 ETS81434.1 - 5e-51 173.7 0.1 7.2e-51 173.2 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase HET PF06985.11 ETS81435.1 - 1.2e-10 42.0 8.1 1.5e-08 35.1 8.1 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cut8 PF08559.10 ETS81436.1 - 1.6e-78 263.7 0.0 1.9e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein MFS_1 PF07690.16 ETS81438.1 - 5.2e-23 81.5 64.2 2.2e-19 69.6 36.8 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily APC_basic PF05956.11 ETS81438.1 - 0.31 10.5 3.9 0.7 9.3 0.4 2.0 2 0 0 2 2 2 0 APC basic domain Glyco_hydro_79C PF16862.5 ETS81439.1 - 1.9e-20 73.7 0.2 3.9e-20 72.7 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain LRR_4 PF12799.7 ETS81440.1 - 1.3e-06 28.7 2.3 0.24 11.9 0.1 6.0 7 0 0 7 7 7 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ETS81440.1 - 2.1e-06 27.5 0.2 8.8e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ETS81440.1 - 0.0017 18.2 0.0 0.0054 16.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain TPR_2 PF07719.17 ETS81440.1 - 0.025 14.7 2.2 4.3 7.7 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 ETS81440.1 - 0.19 12.0 0.4 2.1 8.7 0.2 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ETS81440.1 - 0.38 11.5 1.3 72 4.3 1.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 ETS81440.1 - 0.96 9.2 2.7 31 4.4 0.2 3.5 2 1 2 4 4 4 0 TPR repeat p450 PF00067.22 ETS81441.1 - 1.1e-69 235.4 0.0 1.4e-69 235.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_5 PF07994.12 ETS81442.1 - 6e-145 482.6 0.1 7.3e-145 482.3 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 ETS81442.1 - 3.1e-45 152.9 0.6 7e-45 151.8 0.6 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase LIM PF00412.22 ETS81443.1 - 2.2e-18 66.2 17.9 1e-09 38.5 2.9 3.0 3 0 0 3 3 3 2 LIM domain zf_UBZ PF18439.1 ETS81443.1 - 0.039 13.5 0.1 0.039 13.5 0.1 3.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger AMP-binding PF00501.28 ETS81443.1 - 0.079 11.5 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 AMP-binding enzyme zf_C2HC_14 PF18574.1 ETS81443.1 - 3.7 7.4 5.9 4.2 7.3 1.9 2.5 2 0 0 2 2 2 0 C2HC Zing finger domain Desulfoferrod_N PF06397.12 ETS81443.1 - 7.3 6.3 6.3 0.44 10.2 0.7 1.9 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF3405 PF11885.8 ETS81444.1 - 6e-187 622.3 1.3 6e-187 622.3 1.3 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3405) AFG1_ATPase PF03969.16 ETS81445.1 - 1.9e-55 188.3 0.0 4.1e-26 91.7 0.0 5.0 4 1 1 5 5 5 4 AFG1-like ATPase AAA_16 PF13191.6 ETS81445.1 - 2.8e-05 24.5 0.5 0.008 16.6 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 ETS81445.1 - 0.0011 18.9 0.0 0.003 17.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ETS81445.1 - 0.0052 17.1 0.0 0.015 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 ETS81445.1 - 0.0089 16.0 0.1 0.029 14.3 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 ETS81445.1 - 0.044 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 ETS81445.1 - 0.09 13.3 0.3 1.8 9.1 0.1 2.2 1 1 1 2 2 2 0 ABC transporter AAA PF00004.29 ETS81445.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ETS81445.1 - 0.19 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 ETS81445.1 - 0.27 10.4 0.0 0.42 9.7 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Nucleoporin_C PF03177.14 ETS81446.1 - 8.5e-147 490.4 14.1 1.3e-146 489.8 14.1 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 ETS81446.1 - 2.1e-75 254.2 0.0 2.7e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like MatE PF01554.18 ETS81447.1 - 1.8e-55 187.0 19.0 3.4e-29 101.6 6.3 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 ETS81447.1 - 7.2e-07 29.4 9.6 7.2e-07 29.4 9.6 3.9 3 2 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain DUF679 PF05078.12 ETS81447.1 - 1 9.3 4.0 24 4.9 1.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF679) Pkinase PF00069.25 ETS81448.1 - 5.4e-16 58.7 0.0 2e-13 50.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain WW PF00397.26 ETS81448.1 - 3.2e-06 27.1 1.2 0.038 14.1 0.1 3.0 2 0 0 2 2 2 2 WW domain Pkinase_Tyr PF07714.17 ETS81448.1 - 0.00079 18.8 0.0 0.0026 17.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kelch_5 PF13854.6 ETS81449.1 - 9.5e-12 44.6 0.9 4.1e-07 29.8 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 ETS81449.1 - 3.1e-05 24.1 3.4 0.9 9.9 0.1 5.0 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 ETS81449.1 - 4e-05 23.4 10.5 0.41 10.7 0.2 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 ETS81449.1 - 0.0014 18.6 16.5 0.064 13.3 1.7 4.7 3 2 1 4 4 4 2 Galactose oxidase, central domain Alpha_GJ PF03229.13 ETS81449.1 - 0.07 13.7 0.0 0.19 12.3 0.0 1.7 1 0 0 1 1 1 0 Alphavirus glycoprotein J Gram_pos_anchor PF00746.21 ETS81449.1 - 0.08 12.9 0.3 0.08 12.9 0.3 1.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF5325 PF17259.2 ETS81449.1 - 0.12 12.3 0.5 0.22 11.4 0.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5325) EphA2_TM PF14575.6 ETS81449.1 - 0.18 12.7 0.0 0.34 11.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Kelch_1 PF01344.25 ETS81449.1 - 3.1 7.5 14.4 0.43 10.2 0.2 4.7 5 0 0 5 5 5 0 Kelch motif NACHT PF05729.12 ETS81450.1 - 8.8e-07 29.0 0.0 2.3e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ETS81450.1 - 1.2e-05 25.6 0.3 0.00012 22.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain Helo_like_N PF17111.5 ETS81450.1 - 2.2e-05 24.0 1.4 9.7e-05 21.8 0.9 2.2 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 ETS81450.1 - 0.00015 22.2 0.1 0.0021 18.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 ETS81450.1 - 0.02 15.3 0.0 0.087 13.2 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MCD_N PF17408.2 ETS81450.1 - 0.051 13.7 0.7 0.17 12.0 0.1 2.3 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain Snapin_Pallidin PF14712.6 ETS81450.1 - 0.22 11.9 3.9 1 9.8 3.8 2.2 2 0 0 2 2 2 0 Snapin/Pallidin HET PF06985.11 ETS81451.1 - 1.7e-30 106.3 0.4 3e-30 105.5 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DNA_pol_phi PF04931.13 ETS81452.1 - 0.0039 15.4 9.3 0.005 15.0 9.3 1.1 1 0 0 1 1 1 1 DNA polymerase phi Voldacs PF03517.13 ETS81452.1 - 0.076 13.1 3.9 0.13 12.4 3.9 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling DUF2457 PF10446.9 ETS81452.1 - 0.09 11.9 10.8 0.099 11.8 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 ETS81452.1 - 0.096 12.0 9.2 0.12 11.7 9.2 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 ETS81452.1 - 0.14 12.5 13.3 0.22 11.9 13.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SDA1 PF05285.12 ETS81452.1 - 0.47 9.8 7.4 0.54 9.6 7.4 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 ETS81452.1 - 1.1 9.0 9.8 1.3 8.7 9.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 ETS81452.1 - 1.4 8.9 4.2 1.9 8.5 4.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Nro1 PF12753.7 ETS81452.1 - 2.6 6.9 6.8 3.4 6.5 6.8 1.1 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Sigma70_ner PF04546.13 ETS81452.1 - 3 7.7 8.7 4.4 7.1 8.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 ETS81452.1 - 5.3 5.2 7.2 6.1 5.0 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 ETS81452.1 - 5.6 5.1 8.4 5.8 5.0 8.4 1.1 1 0 0 1 1 1 0 Nop14-like family Dicty_REP PF05086.12 ETS81452.1 - 6.8 4.5 7.5 7.6 4.4 7.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BUD22 PF09073.10 ETS81452.1 - 7.9 5.7 7.3 11 5.3 7.3 1.2 1 0 0 1 1 1 0 BUD22 Cupin_2 PF07883.11 ETS81453.1 - 4.1e-07 29.6 0.2 6.5e-07 29.0 0.2 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ETS81453.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Cupin PS_Dcarbxylase PF02666.15 ETS81454.1 - 3.8e-56 189.8 0.0 6.9e-56 189.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 ETS81454.1 - 6.2e-38 129.2 0.0 7.5e-18 64.7 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.32 ETS81454.1 - 0.0026 17.2 0.3 0.0075 15.7 0.0 2.0 2 0 0 2 2 2 1 EF hand CEP76-C2 PF15627.6 ETS81454.1 - 0.018 14.6 0.0 6.8 6.2 0.0 2.4 2 0 0 2 2 2 0 CEP76 C2 domain EF-hand_5 PF13202.6 ETS81454.1 - 0.033 13.7 0.0 0.099 12.2 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 ETS81454.1 - 0.04 13.8 0.5 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain PBP1_TM PF14812.6 ETS81454.1 - 1.6 9.2 7.5 5.9 7.3 7.5 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HAD PF12710.7 ETS81455.1 - 4.9e-24 85.8 0.0 7.5e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 ETS81455.1 - 0.0057 16.1 0.0 0.59 9.5 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.26 ETS81455.1 - 0.048 13.9 0.1 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 ETS81455.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Coatomer_E PF04733.14 ETS81456.1 - 4.9e-64 216.5 9.0 5.6e-64 216.3 9.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 ETS81456.1 - 6.1e-11 42.7 24.0 3.6e-05 24.2 3.3 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ETS81456.1 - 0.00028 21.5 22.2 0.015 16.0 0.2 5.4 5 1 1 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS81456.1 - 0.002 18.3 2.0 5 7.4 0.1 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 ETS81456.1 - 0.0029 16.9 8.9 0.01 15.1 0.8 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 ETS81456.1 - 0.0054 17.0 15.7 0.34 11.2 1.4 4.9 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 ETS81456.1 - 0.006 16.7 8.6 0.26 11.5 0.1 4.0 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 ETS81456.1 - 0.0089 15.7 0.4 0.0089 15.7 0.4 3.4 4 0 0 4 4 4 1 TPR repeat Fis1_TPR_C PF14853.6 ETS81456.1 - 0.016 15.3 0.2 0.016 15.3 0.2 2.4 4 0 0 4 4 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 ETS81456.1 - 0.019 15.6 2.9 0.019 15.6 2.9 4.2 2 2 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 ETS81456.1 - 0.03 14.4 0.0 0.03 14.4 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 ETS81456.1 - 0.032 14.4 3.8 11 6.6 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ETS81456.1 - 0.045 14.4 5.3 2.3 9.0 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Asparaginase_2 PF01112.18 ETS81456.1 - 0.053 12.5 5.5 0.093 11.7 5.5 1.3 1 0 0 1 1 1 0 Asparaginase Type_III_YscG PF09477.10 ETS81456.1 - 0.064 13.3 5.9 0.086 12.9 0.5 3.0 2 1 2 4 4 4 0 Bacterial type II secretion system chaperone protein (type_III_yscG) UBA_4 PF14555.6 ETS81456.1 - 0.11 12.4 0.6 8 6.4 0.0 2.8 2 0 0 2 2 2 0 UBA-like domain Smr PF01713.21 ETS81456.1 - 0.23 11.9 2.4 9.2 6.7 0.3 3.2 2 1 0 2 2 2 0 Smr domain TPR_1 PF00515.28 ETS81456.1 - 3.1 7.8 8.6 1.9 8.5 0.0 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 ETS81456.1 - 7.6 6.9 11.4 11 6.5 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 ETS81456.1 - 8.9 7.3 18.1 2.5 9.0 0.1 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF4590 PF15257.6 ETS81457.1 - 0.045 13.7 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) AAA PF00004.29 ETS81458.1 - 1.4e-17 64.4 0.0 2.6e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS81458.1 - 0.0011 19.4 0.4 0.0035 17.8 0.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS81458.1 - 0.0036 17.6 0.1 0.017 15.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain Zot PF05707.12 ETS81458.1 - 0.0095 15.6 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_33 PF13671.6 ETS81458.1 - 0.01 16.0 0.3 0.11 12.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 ETS81458.1 - 0.2 11.4 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain MeaB PF03308.16 ETS81458.1 - 0.72 8.8 2.6 0.41 9.6 0.2 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Yip1 PF04893.17 ETS81459.1 - 1.3 8.7 10.7 3.8 7.2 1.1 2.3 1 1 0 2 2 2 0 Yip1 domain Aminotran_1_2 PF00155.21 ETS81460.1 - 8.1e-66 222.6 0.0 9.2e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ETS81460.1 - 0.0026 16.8 0.0 0.0062 15.5 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ETS81460.1 - 0.0048 16.2 0.0 0.011 15.1 0.0 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 ETS81460.1 - 0.0059 15.2 0.1 0.016 13.7 0.1 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 ETS81460.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Peptidase_M78 PF06114.13 ETS81460.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 IrrE N-terminal-like domain Fungal_trans_2 PF11951.8 ETS81461.1 - 7.6e-55 186.3 0.6 9.9e-55 185.9 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 ETS81461.1 - 0.014 14.4 0.1 0.048 12.7 0.1 2.0 1 1 0 1 1 1 0 Fungal specific transcription factor domain Abhydrolase_3 PF07859.13 ETS81462.1 - 3e-43 148.1 0.0 3.9e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS81462.1 - 4.5e-07 29.1 0.0 1.1e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 ETS81462.1 - 0.00032 21.4 0.4 0.00066 20.3 0.1 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 ETS81462.1 - 0.031 13.1 0.0 0.043 12.7 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Sugar_tr PF00083.24 ETS81463.1 - 1.8e-71 241.4 22.7 2.3e-71 241.0 22.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS81463.1 - 1.7e-15 56.8 46.9 3.7e-12 45.8 14.3 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily PhyH PF05721.13 ETS81464.1 - 1e-10 42.3 0.0 1.5e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 ETS81464.1 - 7.4e-07 28.3 0.1 0.11 11.3 0.1 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) FAD-oxidase_C PF02913.19 ETS81465.1 - 1.5e-62 211.5 0.0 2.5e-62 210.8 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ETS81465.1 - 2.4e-37 127.8 0.0 4.3e-37 126.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 ETS81465.1 - 0.083 11.6 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Peptidase_S51 PF03575.17 ETS81466.1 - 3.8e-17 62.6 0.0 4.6e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S51 HET PF06985.11 ETS81467.1 - 2.1e-35 122.2 1.1 2.1e-35 122.2 1.1 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Yqai PF09466.10 ETS81467.1 - 0.0034 17.6 9.1 0.51 10.7 0.1 5.7 7 1 0 7 7 7 2 Hypothetical protein Yqai MFS_1 PF07690.16 ETS81469.1 - 6.8e-32 110.7 25.4 6.8e-32 110.7 25.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3367 PF11847.8 ETS81469.1 - 4.5 5.0 8.4 0.45 8.3 1.0 2.1 2 0 0 2 2 2 0 Alpha-(1->3)-arabinofuranosyltransferase Acetyltransf_1 PF00583.25 ETS81470.1 - 3.7e-07 30.4 0.0 4.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS81470.1 - 0.00094 19.6 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS81470.1 - 0.036 14.0 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS81470.1 - 0.054 13.5 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Glyco_hydro_61 PF03443.14 ETS81471.1 - 2e-50 171.6 0.4 2.4e-50 171.3 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAR2 PF16974.5 ETS81471.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory Methyltransf_25 PF13649.6 ETS81472.1 - 1.1e-17 64.5 0.0 2.7e-17 63.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS81472.1 - 5.5e-15 55.8 0.0 9.7e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS81472.1 - 2.9e-10 40.2 0.0 4.2e-10 39.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS81472.1 - 6.2e-09 36.5 0.0 1.7e-08 35.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS81472.1 - 2.2e-08 34.0 0.0 2.9e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS81472.1 - 3.5e-06 26.5 0.0 4.9e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 ETS81472.1 - 4.6e-06 26.1 0.0 5.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 ETS81472.1 - 0.00014 21.3 0.0 0.00018 20.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 ETS81472.1 - 0.00033 20.2 0.0 0.0013 18.3 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase small domain CheR PF01739.18 ETS81472.1 - 0.0063 16.0 0.0 0.57 9.6 0.0 2.3 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain PCMT PF01135.19 ETS81472.1 - 0.015 15.1 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.11 ETS81472.1 - 0.023 14.4 0.0 0.055 13.1 0.0 1.6 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_16 PF10294.9 ETS81472.1 - 0.058 13.1 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase TehB PF03848.14 ETS81472.1 - 0.09 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB PrmA PF06325.13 ETS81472.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_10 PF05971.12 ETS81472.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 RNA methyltransferase BNR PF02012.20 ETS81473.1 - 0.063 13.3 0.3 0.44 10.7 0.0 2.7 2 0 0 2 2 2 0 BNR/Asp-box repeat Methyltransf_23 PF13489.6 ETS81475.1 - 4.6e-19 68.8 0.0 9.5e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain zf-His_Me_endon PF05551.11 ETS81475.1 - 4.9e-14 52.7 2.9 1e-13 51.6 2.9 1.5 1 0 0 1 1 1 1 Zinc-binding loop region of homing endonuclease Methyltransf_25 PF13649.6 ETS81475.1 - 2.5e-06 28.1 0.0 1.4e-05 25.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS81475.1 - 7e-06 25.9 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 ETS81475.1 - 1.3e-05 25.8 0.0 5.7e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS81475.1 - 0.003 18.2 0.0 0.031 14.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain zf-C2H2 PF00096.26 ETS81475.1 - 0.033 14.6 2.3 0.21 12.1 1.0 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF938 PF06080.12 ETS81475.1 - 0.066 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) zf-C2H2_4 PF13894.6 ETS81475.1 - 0.13 13.2 3.1 3.2 8.8 1.1 3.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 ETS81475.1 - 0.14 12.2 2.9 3.3 7.8 0.4 2.7 2 0 0 2 2 2 0 BED zinc finger Ubie_methyltran PF01209.18 ETS81475.1 - 0.18 11.1 0.0 0.46 9.8 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF3716 PF12511.8 ETS81477.1 - 0.00026 21.0 12.6 0.00043 20.3 12.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) zf-C2H2 PF00096.26 ETS81479.1 - 0.0076 16.7 0.9 0.0076 16.7 0.9 10.9 12 0 0 12 12 12 3 Zinc finger, C2H2 type zf-C2H2_12 PF18658.1 ETS81479.1 - 0.42 10.2 11.0 0.53 9.9 0.2 4.4 3 1 1 4 4 4 0 Zinc-finger C2H2-type OEP PF02321.18 ETS81484.1 - 0.0024 17.7 0.4 0.0037 17.1 0.4 1.2 1 0 0 1 1 1 1 Outer membrane efflux protein GAS PF13851.6 ETS81484.1 - 0.011 15.1 2.5 0.015 14.6 2.5 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding WEMBL PF05701.11 ETS81484.1 - 0.017 13.9 1.2 0.022 13.5 1.2 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Perilipin PF03036.16 ETS81484.1 - 0.02 13.9 0.6 0.022 13.8 0.6 1.1 1 0 0 1 1 1 0 Perilipin family DUF1351 PF07083.11 ETS81484.1 - 0.036 13.8 0.2 0.049 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) Occludin_ELL PF07303.13 ETS81484.1 - 0.073 13.8 0.6 0.28 11.9 0.2 2.0 1 1 1 2 2 2 0 Occludin homology domain Snapin_Pallidin PF14712.6 ETS81484.1 - 0.079 13.4 0.5 0.15 12.5 0.5 1.5 1 1 0 1 1 1 0 Snapin/Pallidin UPF0449 PF15136.6 ETS81484.1 - 0.31 11.5 4.2 0.11 13.0 0.9 2.0 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 MRI PF15325.6 ETS81484.1 - 0.44 11.7 2.8 0.83 10.8 2.8 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection Comm PF15957.5 ETS81485.1 - 0.035 14.5 0.2 0.2 12.0 0.2 2.4 1 1 0 1 1 1 0 Commissureless MutS_III PF05192.18 ETS81485.1 - 0.096 12.9 16.8 3.8 7.7 1.3 3.6 1 1 1 2 2 2 0 MutS domain III FBA_3 PF08268.12 ETS81485.1 - 0.15 12.0 0.0 7.7 6.5 0.0 2.4 1 1 1 2 2 2 0 F-box associated domain TfuA PF07812.12 ETS81485.1 - 0.2 11.4 3.3 3.5 7.4 0.5 2.6 2 1 0 2 2 2 0 TfuA-like protein Helo_like_N PF17111.5 ETS81485.1 - 0.55 9.6 16.3 2.3 7.6 0.7 4.0 1 1 1 3 3 3 0 Fungal N-terminal domain of STAND proteins PspB PF06667.12 ETS81485.1 - 0.66 10.1 15.7 3.2 7.9 0.9 4.3 3 2 2 5 5 5 0 Phage shock protein B Exonuc_VII_L PF02601.15 ETS81485.1 - 0.69 9.4 15.3 11 5.4 15.3 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF3861 PF12977.7 ETS81485.1 - 1 9.6 7.7 0.67 10.2 0.3 3.3 2 2 1 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) FUSC PF04632.12 ETS81485.1 - 1.3 7.4 13.7 1.6 7.1 3.2 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family TMPIT PF07851.13 ETS81485.1 - 1.6 7.9 9.4 4.6 6.4 1.7 2.2 1 1 1 2 2 2 0 TMPIT-like protein EMP24_GP25L PF01105.24 ETS81485.1 - 1.8 8.5 12.4 4 7.3 0.7 2.7 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD SpmSyn_N PF17950.1 ETS81485.1 - 2.7 8.2 7.5 2 8.6 0.6 3.1 1 1 2 3 3 3 0 S-adenosylmethionine decarboxylase N -terminal Fzo_mitofusin PF04799.13 ETS81485.1 - 2.9 7.4 14.3 3.2 7.3 6.4 2.2 2 0 0 2 2 2 0 fzo-like conserved region Prominin PF05478.11 ETS81485.1 - 6.7 4.5 11.9 4.4 5.1 4.7 1.8 1 1 1 2 2 2 0 Prominin Seryl_tRNA_N PF02403.22 ETS81488.1 - 0.023 14.9 0.3 0.049 13.9 0.3 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 ETS81488.1 - 0.14 12.9 0.0 0.29 11.8 0.0 1.5 1 0 0 1 1 1 0 Initiation control protein YabA HET PF06985.11 ETS81490.1 - 1.3e-22 80.7 0.0 2.9e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GFO_IDH_MocA PF01408.22 ETS81491.1 - 4.3e-23 82.4 0.0 8.4e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ETS81491.1 - 1e-06 28.7 0.0 2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.15 ETS81491.1 - 0.13 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sugar_tr PF00083.24 ETS81492.1 - 1.4e-91 307.7 32.9 1.6e-91 307.4 32.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS81492.1 - 1e-34 120.0 31.7 1e-34 120.0 31.7 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS81492.1 - 1.6e-05 23.6 3.0 3.2e-05 22.6 3.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cation_ATPase_C PF00689.21 ETS81492.1 - 9.6 5.9 16.3 0.077 12.7 6.0 2.6 2 2 0 2 2 2 0 Cation transporting ATPase, C-terminus TRP PF06011.12 ETS81493.1 - 4.9e-06 25.5 28.3 1.4e-05 24.0 22.3 2.9 2 1 0 2 2 2 2 Transient receptor potential (TRP) ion channel Vps36-NZF-N PF16988.5 ETS81493.1 - 0.052 12.9 0.1 0.14 11.5 0.1 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Peptidase_M24 PF00557.24 ETS81495.1 - 1.2e-20 74.2 0.0 1.4e-20 73.9 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 MACPF PF01823.19 ETS81499.1 - 0.096 12.8 2.8 0.12 12.5 0.4 2.2 2 1 0 2 2 2 0 MAC/Perforin domain Jacalin PF01419.17 ETS81500.1 - 1.7e-06 28.0 0.0 4.6e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Jacalin-like lectin domain Spc7 PF08317.11 ETS81500.1 - 8 5.2 59.5 4.5 6.0 25.5 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1492 PF07374.11 ETS81500.1 - 9.5 6.5 8.9 2.8 8.2 2.2 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1492) Zn_clus PF00172.18 ETS81501.1 - 8.1e-09 35.5 10.5 8.1e-09 35.5 10.5 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ETS81502.1 - 6.9e-33 114.0 27.8 6.9e-33 114.0 27.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS81502.1 - 1.3e-13 50.7 6.1 1.3e-13 50.7 6.1 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter CCSMST1 PF15013.6 ETS81502.1 - 0.23 11.7 0.9 0.86 9.8 0.9 2.0 1 0 0 1 1 1 0 CCSMST1 family DUF3237 PF11578.8 ETS81503.1 - 8.2e-28 97.1 0.0 9.8e-28 96.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Amidase PF01425.21 ETS81504.1 - 4.7e-92 309.3 0.0 9.8e-92 308.2 0.0 1.5 1 1 0 1 1 1 1 Amidase HET PF06985.11 ETS81505.1 - 1.3e-20 74.2 0.6 3.4e-20 72.9 0.6 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PNKP_ligase PF16542.5 ETS81505.1 - 0.029 13.9 0.2 0.054 13.0 0.2 1.3 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain AAA PF00004.29 ETS81506.1 - 2.6e-17 63.5 0.0 6.8e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 ETS81506.1 - 0.00051 19.5 1.2 0.013 14.9 0.6 2.2 1 1 1 2 2 2 1 KaiC AAA_16 PF13191.6 ETS81506.1 - 0.0018 18.7 0.2 0.0062 16.9 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ETS81506.1 - 0.0037 17.3 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 ETS81506.1 - 0.013 15.2 0.4 0.033 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 ETS81506.1 - 0.026 14.6 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 ETS81506.1 - 0.031 14.5 0.4 0.22 11.8 0.1 2.2 1 1 1 2 2 2 0 AAA domain Zot PF05707.12 ETS81506.1 - 0.051 13.2 0.0 0.55 9.8 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) RuvB_N PF05496.12 ETS81506.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 ETS81506.1 - 0.16 12.5 0.1 4.2 7.9 0.1 3.0 2 1 0 2 2 2 0 AAA domain Caskin-Pro-rich PF16907.5 ETS81506.1 - 0.58 10.7 2.5 1.9 9.0 2.5 1.9 1 0 0 1 1 1 0 Proline rich region of Caskin proteins adh_short_C2 PF13561.6 ETS81507.1 - 1.6e-52 178.4 0.1 2.1e-52 178.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS81507.1 - 6e-45 153.1 0.4 8e-45 152.7 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS81507.1 - 5e-07 29.8 0.1 7.6e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS81507.1 - 0.032 13.7 0.2 0.05 13.1 0.2 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1614 PF07758.11 ETS81507.1 - 0.078 13.0 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1614) adh_short_C2 PF13561.6 ETS81508.1 - 1e-54 185.6 0.0 2.6e-54 184.2 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS81508.1 - 2.6e-43 147.8 0.7 7.9e-43 146.2 0.7 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS81508.1 - 4.4e-09 36.5 0.1 6.8e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Sugar_tr PF00083.24 ETS81509.1 - 5.4e-92 309.0 22.5 6.8e-92 308.7 22.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS81509.1 - 1.3e-24 86.9 44.7 2.2e-17 63.0 17.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS81509.1 - 0.0016 17.0 2.5 0.0034 15.9 2.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 ETS81509.1 - 1.6 6.9 11.0 0.033 12.5 0.3 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Aldo_ket_red PF00248.21 ETS81510.1 - 2.9e-44 151.5 0.0 4.1e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family F_bP_aldolase PF01116.20 ETS81511.1 - 5.7e-81 272.1 0.1 6.4e-81 271.9 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II SGL PF08450.12 ETS81512.1 - 4.4e-29 101.8 0.0 1.1e-28 100.5 0.0 1.7 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 ETS81512.1 - 0.0041 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Arylesterase Str_synth PF03088.16 ETS81512.1 - 0.0043 17.1 0.0 0.034 14.3 0.0 2.3 3 0 0 3 3 3 1 Strictosidine synthase NHL PF01436.21 ETS81512.1 - 0.036 14.1 0.5 0.79 9.9 0.0 3.1 3 0 0 3 3 3 0 NHL repeat adh_short_C2 PF13561.6 ETS81513.1 - 8.6e-56 189.1 0.4 1e-55 188.9 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS81513.1 - 2.8e-42 144.4 1.2 3.5e-42 144.1 1.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS81513.1 - 6e-12 45.8 1.4 8.7e-12 45.3 1.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS81513.1 - 0.052 13.0 0.2 0.079 12.4 0.2 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Abhydrolase_6 PF12697.7 ETS81515.1 - 0.0053 17.4 0.0 0.0075 16.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans_2 PF11951.8 ETS81516.1 - 4.5e-14 52.1 0.2 7.2e-14 51.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS81516.1 - 4.5e-08 33.1 15.5 4.5e-08 33.1 15.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS81516.1 - 0.00022 20.3 1.1 0.00035 19.7 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_62 PF03664.13 ETS81517.1 - 1.8e-152 506.3 20.5 2e-152 506.1 20.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 DUF2475 PF10629.9 ETS81517.1 - 0.062 13.5 0.2 0.69 10.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2475) FA_desaturase PF00487.24 ETS81518.1 - 2.2e-30 106.4 21.5 3.1e-30 105.9 21.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ETS81518.1 - 6.1e-11 42.3 0.0 1.4e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mem_trans PF03547.18 ETS81518.1 - 0.018 13.4 0.0 0.034 12.6 0.0 1.3 1 0 0 1 1 1 0 Membrane transport protein FAD_binding_4 PF01565.23 ETS81519.1 - 1.5e-22 79.8 0.4 2.5e-22 79.1 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS81519.1 - 0.0011 19.1 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.14 ETS81519.1 - 0.077 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase OGFr_N PF04664.13 ETS81519.1 - 0.21 11.1 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region COesterase PF00135.28 ETS81520.1 - 3.9e-59 200.9 0.0 5.8e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS81520.1 - 8.7e-08 32.3 1.6 2.8e-07 30.6 1.6 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS81520.1 - 0.009 14.9 0.0 3.4 6.4 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase GMC_oxred_N PF00732.19 ETS81521.1 - 1.2e-64 218.5 0.1 1.6e-64 218.2 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS81521.1 - 1.1e-32 113.5 0.1 1.8e-32 112.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 ETS81521.1 - 3.3e-05 24.0 0.1 0.0001 22.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ETS81521.1 - 8.3e-05 21.8 0.0 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 ETS81521.1 - 0.0001 22.0 0.1 0.0035 17.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS81521.1 - 0.00012 20.9 0.1 0.062 12.0 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 ETS81521.1 - 0.00014 21.1 0.2 0.055 12.5 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 ETS81521.1 - 0.00057 19.2 0.3 0.0013 18.0 0.3 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 ETS81521.1 - 0.0036 16.6 0.1 1.2 8.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS81521.1 - 0.0046 16.2 0.4 0.23 10.6 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS81521.1 - 0.08 13.5 0.1 0.47 11.1 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ETS81521.1 - 0.14 12.4 0.6 0.37 11.1 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain HET PF06985.11 ETS81522.1 - 7.5e-26 91.2 0.1 1.3e-25 90.5 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.23 ETS81523.1 - 1.3e-08 34.6 0.1 3.1e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain p450 PF00067.22 ETS81524.1 - 1.9e-44 152.2 0.0 2.9e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Sulfatase PF00884.23 ETS81525.1 - 6e-47 160.5 0.0 7.9e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 ETS81525.1 - 0.00094 18.9 0.0 0.025 14.2 0.0 2.4 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 ETS81525.1 - 0.0012 19.0 0.2 0.0023 18.2 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 ETS81525.1 - 0.2 10.2 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) ADH_zinc_N PF00107.26 ETS81526.1 - 4e-23 81.8 0.6 6.2e-23 81.2 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS81526.1 - 2.4e-12 48.0 0.0 6.5e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS81526.1 - 1.5e-07 31.3 0.0 2.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 ETS81526.1 - 4.5e-06 26.3 0.5 7.3e-06 25.6 0.5 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 ETS81526.1 - 0.031 13.5 0.4 0.05 12.9 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Abhydrolase_1 PF00561.20 ETS81527.1 - 3.2e-20 72.9 0.1 9e-20 71.4 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS81527.1 - 6e-14 53.2 0.1 7.4e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS81527.1 - 7.2e-12 45.1 0.0 3e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ETS81527.1 - 0.0025 17.3 0.0 0.017 14.6 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ETS81527.1 - 0.006 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) CFEM PF05730.11 ETS81528.1 - 3.4e-13 49.5 11.2 5.2e-13 48.9 11.2 1.3 1 0 0 1 1 1 1 CFEM domain FAD_binding_4 PF01565.23 ETS81529.1 - 8.2e-20 71.0 5.0 8.2e-20 71.0 5.0 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 ETS81529.1 - 4.1e-11 42.8 1.3 7.4e-11 42.0 1.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like Ank_2 PF12796.7 ETS81530.1 - 3.6e-31 107.6 8.8 9.3e-12 45.4 0.0 8.2 6 2 2 8 8 8 6 Ankyrin repeats (3 copies) NACHT_N PF17100.5 ETS81530.1 - 3.6e-23 82.6 5.0 3.6e-12 46.6 0.0 3.0 2 1 1 3 3 3 2 N-terminal domain of NWD NACHT-NTPase Ank_4 PF13637.6 ETS81530.1 - 2.9e-22 78.8 9.9 1.7e-05 25.2 0.0 9.7 7 3 3 11 11 10 6 Ankyrin repeats (many copies) Ank PF00023.30 ETS81530.1 - 4.1e-20 71.3 22.8 0.014 15.8 0.0 10.4 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 ETS81530.1 - 1.3e-17 63.6 20.8 0.00016 21.9 0.0 8.6 9 1 1 10 10 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS81530.1 - 8.3e-17 59.6 11.6 0.056 14.0 0.0 10.7 11 0 0 11 11 10 4 Ankyrin repeat NACHT PF05729.12 ETS81530.1 - 2.1e-08 34.3 0.0 1.4e-07 31.6 0.0 2.4 2 1 1 3 3 3 1 NACHT domain AAA_22 PF13401.6 ETS81530.1 - 5e-05 23.6 0.0 0.00019 21.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS81530.1 - 0.00087 19.7 0.9 0.047 14.1 0.1 3.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.7 ETS81530.1 - 0.051 12.5 0.3 0.75 8.6 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain AAA PF00004.29 ETS81530.1 - 0.096 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 ETS81530.1 - 0.16 12.0 1.9 0.3 11.1 0.2 2.2 3 0 0 3 3 3 0 Helicase HerA, central domain DUF2937 PF11157.8 ETS81530.1 - 2.5 7.8 4.7 17 5.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF1690 PF07956.11 ETS81530.1 - 3.2 8.2 5.8 0.43 11.0 0.3 2.2 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Sugar_tr PF00083.24 ETS81532.1 - 7.4e-91 305.3 27.1 8.7e-91 305.0 27.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS81532.1 - 6.7e-12 45.0 41.6 1e-10 41.1 32.3 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PIG-P PF08510.12 ETS81532.1 - 0.15 12.0 1.0 0.48 10.4 1.0 1.9 1 0 0 1 1 1 0 PIG-P Abhydrolase_3 PF07859.13 ETS81533.1 - 1.1e-44 152.8 0.0 1.6e-44 152.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS81533.1 - 1.4e-08 34.0 0.0 4e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Fungal_trans_2 PF11951.8 ETS81534.1 - 3.8e-20 72.1 2.1 1.2e-19 70.4 2.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS81534.1 - 9.8e-09 35.2 10.4 1.8e-08 34.4 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_16 PF13432.6 ETS81534.1 - 3.9 8.2 6.0 7.5 7.3 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1479 PF07350.12 ETS81535.1 - 4.6e-130 434.1 0.0 5.5e-130 433.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 ETS81535.1 - 0.079 13.2 0.0 0.35 11.1 0.0 2.1 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) p450 PF00067.22 ETS81536.1 - 2.1e-39 135.6 0.0 2.8e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS81537.1 - 1.4e-65 221.8 0.0 1.8e-65 221.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 ETS81538.1 - 2.1e-44 151.9 26.9 2.1e-44 151.9 26.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS81538.1 - 1.6e-10 40.4 15.2 1.6e-10 40.4 15.2 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 ETS81538.1 - 1.4e-05 24.5 10.0 1.4e-05 24.5 10.0 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Transgly_assoc PF04226.13 ETS81538.1 - 3.7 7.9 10.4 0.35 11.2 3.8 2.9 2 0 0 2 2 2 0 Transglycosylase associated protein DUF1129 PF06570.11 ETS81538.1 - 8.5 5.8 7.9 0.88 9.0 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Fungal_trans_2 PF11951.8 ETS81539.1 - 0.00016 20.7 1.4 0.00019 20.4 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Spp-24 PF07448.11 ETS81539.1 - 8.4 6.7 8.4 4.7 7.5 5.4 2.0 2 0 0 2 2 2 0 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain MFS_1 PF07690.16 ETS81540.1 - 2.9e-38 131.7 22.3 3.6e-38 131.4 22.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF485 PF04341.12 ETS81540.1 - 0.00036 20.4 4.2 0.0018 18.2 0.0 3.6 1 1 2 3 3 3 1 Protein of unknown function, DUF485 Amidohydro_2 PF04909.14 ETS81541.1 - 1.1e-13 51.6 1.0 5.3e-13 49.4 1.0 2.1 1 1 0 1 1 1 1 Amidohydrolase Type_III_YscX PF09474.10 ETS81541.1 - 0.16 12.2 0.3 1.1 9.5 0.1 2.2 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) Fungal_trans PF04082.18 ETS81542.1 - 3.9e-16 58.9 0.6 5e-16 58.5 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_15 PF13429.6 ETS81542.1 - 0.084 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Fungal_trans PF04082.18 ETS81543.1 - 3.1e-15 56.0 0.2 5.5e-15 55.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhosphMutase PF10143.9 ETS81543.1 - 0.062 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 2-Hacid_dh_C PF02826.19 ETS81544.1 - 3.1e-47 160.2 0.0 4.4e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS81544.1 - 1.6e-21 76.3 0.0 1.9e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ETS81544.1 - 5e-05 23.5 0.0 0.00022 21.4 0.0 2.0 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 ETS81544.1 - 0.003 17.6 0.0 0.0053 16.8 0.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.17 ETS81544.1 - 0.083 13.5 0.1 0.27 11.9 0.1 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SGL PF08450.12 ETS81545.1 - 2.7e-46 158.1 0.0 3.4e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 ETS81545.1 - 2.7e-09 36.6 0.4 0.052 13.6 0.0 6.0 6 0 0 6 6 6 2 NHL repeat Str_synth PF03088.16 ETS81545.1 - 3.3e-07 30.3 0.0 0.0011 19.0 0.1 3.9 3 2 1 4 4 4 2 Strictosidine synthase Arylesterase PF01731.20 ETS81545.1 - 7.6e-06 26.0 0.0 0.0028 17.8 0.0 3.0 2 1 1 3 3 3 1 Arylesterase Lactonase PF10282.9 ETS81545.1 - 0.0028 16.9 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SBBP PF06739.11 ETS81545.1 - 0.005 16.8 0.4 6.9 6.8 0.2 3.5 3 0 0 3 3 3 2 Beta-propeller repeat SdiA-regulated PF06977.11 ETS81545.1 - 0.22 10.7 0.1 9.9 5.3 0.0 2.6 2 1 0 2 2 2 0 SdiA-regulated Sugar_tr PF00083.24 ETS81546.1 - 1.9e-95 320.4 15.4 2.2e-95 320.2 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS81546.1 - 1e-22 80.6 10.1 1e-22 80.6 10.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NACHT PF05729.12 ETS81548.1 - 1.4e-18 67.3 0.1 3.5e-18 66.1 0.1 1.7 1 0 0 1 1 1 1 NACHT domain HET PF06985.11 ETS81548.1 - 3.3e-11 43.7 5.5 2e-09 38.0 0.1 3.0 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 ETS81548.1 - 0.0015 19.3 0.0 0.0059 17.4 0.0 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat KAP_NTPase PF07693.14 ETS81548.1 - 0.017 14.4 0.2 0.3 10.3 0.1 2.2 1 1 0 2 2 2 0 KAP family P-loop domain HAD PF12710.7 ETS81548.1 - 0.12 12.8 0.1 0.33 11.3 0.1 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sugar_tr PF00083.24 ETS81549.1 - 1.5e-84 284.5 26.4 1.7e-84 284.3 26.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS81549.1 - 7.6e-24 84.3 48.8 2.3e-21 76.1 26.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS81549.1 - 0.00031 19.3 2.1 0.00031 19.3 2.1 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) F_bP_aldolase PF01116.20 ETS81550.1 - 1.8e-79 267.2 0.0 2e-79 267.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Epimerase PF01370.21 ETS81551.1 - 1.9e-17 63.5 0.0 2.4e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS81551.1 - 2.8e-12 46.2 0.0 3.7e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ETS81551.1 - 3e-10 40.0 0.0 1.9e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ETS81551.1 - 5.1e-08 32.4 0.0 9.7e-08 31.4 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ETS81551.1 - 2.8e-05 23.4 0.0 0.17 11.0 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein Ldh_1_N PF00056.23 ETS81551.1 - 0.00098 19.2 0.1 0.0017 18.5 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 ETS81551.1 - 0.0043 17.0 0.1 0.03 14.3 0.1 2.2 2 1 1 3 3 3 1 KR domain Polysacc_synt_2 PF02719.15 ETS81551.1 - 0.01 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 ETS81551.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.20 ETS81551.1 - 0.14 12.3 0.1 0.23 11.6 0.1 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PhyH PF05721.13 ETS81552.1 - 4.4e-12 46.7 0.2 8.9e-12 45.7 0.2 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 ETS81552.1 - 1.1e-06 27.7 0.0 0.029 13.2 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_3 PF13640.6 ETS81552.1 - 0.086 13.7 0.0 0.18 12.7 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 ETS81553.1 - 9.8e-12 44.5 0.1 1.9e-11 43.5 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain 2-Hacid_dh_C PF02826.19 ETS81554.1 - 3.5e-52 176.3 0.0 4.6e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS81554.1 - 8.3e-18 64.3 0.0 9.6e-18 64.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 ETS81554.1 - 0.082 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 ETS81554.1 - 0.096 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Lactamase_B_2 PF12706.7 ETS81556.1 - 2.5e-09 37.0 0.0 3.9e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ETS81556.1 - 1.1e-07 31.9 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ETS81556.1 - 0.058 13.4 0.4 0.96 9.4 0.0 2.7 1 1 0 2 2 2 0 Metallo-beta-lactamase superfamily p450 PF00067.22 ETS81557.1 - 4.6e-67 226.7 0.0 6.1e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 ETS81558.1 - 5e-08 32.9 4.1 5e-08 32.9 4.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 ETS81559.1 - 1.4e-78 264.0 0.0 2.7e-78 263.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 ETS81559.1 - 5.1e-70 235.9 0.0 7.4e-69 232.1 0.0 2.5 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 ETS81559.1 - 4.3e-35 121.7 0.0 7.2e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ETS81559.1 - 3.9e-31 107.5 0.3 8.6e-31 106.4 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 ETS81559.1 - 1.8e-23 83.0 0.0 4.6e-23 81.7 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.25 ETS81559.1 - 2.4e-21 75.8 6.7 9.2e-11 41.9 1.0 2.9 3 0 0 3 3 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 ETS81559.1 - 2.1e-15 56.7 0.1 3.7e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 ETS81559.1 - 6.5e-07 29.8 0.0 2.3e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 ETS81559.1 - 1.1e-05 25.0 0.0 4.5e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Epimerase PF01370.21 ETS81559.1 - 3.2e-05 23.5 0.0 6.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ETS81559.1 - 0.09 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 ETS81559.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 ETS81560.1 - 5.2e-10 39.4 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS81560.1 - 1.5e-07 31.3 0.0 6.4e-07 29.2 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ETS81560.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Semialdhyde_dh PF01118.24 ETS81560.1 - 0.061 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Aldo_ket_red PF00248.21 ETS81561.1 - 2.8e-54 184.3 0.0 3.1e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_4 PF01565.23 ETS81562.1 - 6.6e-24 84.2 0.5 3.2e-23 82.0 0.7 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 ETS81562.1 - 7.7e-06 25.9 0.5 2.1e-05 24.5 0.5 1.8 1 0 0 1 1 1 1 Berberine and berberine like GMC_oxred_N PF00732.19 ETS81563.1 - 1.6e-64 218.1 0.1 2.4e-64 217.6 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS81563.1 - 2.3e-29 102.8 0.0 4.6e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ETS81563.1 - 7.9e-06 25.2 0.0 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ETS81563.1 - 3.2e-05 23.3 0.0 0.014 14.7 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS81563.1 - 4.1e-05 22.8 0.1 0.038 13.1 0.0 2.8 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 ETS81563.1 - 8.9e-05 22.6 0.0 0.00024 21.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS81563.1 - 0.0021 17.4 0.0 0.0078 15.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS81563.1 - 0.0036 16.6 0.1 0.0072 15.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 ETS81563.1 - 0.0051 16.4 0.3 0.042 13.4 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ETS81563.1 - 0.0081 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ETS81563.1 - 0.019 13.7 0.0 0.032 12.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 ETS81563.1 - 0.047 13.7 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 ETS81563.1 - 0.25 11.6 1.6 0.89 9.8 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Aconitase PF00330.20 ETS81564.1 - 9.2e-148 493.0 0.0 1.2e-147 492.6 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ETS81564.1 - 6.4e-38 130.0 0.0 1.2e-37 129.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF1749 PF08538.10 ETS81565.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Actin PF00022.19 ETS81566.1 - 1.9e-126 422.0 0.0 7.4e-126 420.0 0.0 1.7 1 1 0 1 1 1 1 Actin DUF4692 PF15763.5 ETS81566.1 - 0.079 13.4 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) COesterase PF00135.28 ETS81567.1 - 5.3e-56 190.6 4.6 2.8e-55 188.2 4.6 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS81567.1 - 0.0011 18.9 1.2 0.0053 16.6 0.1 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF3602 PF12223.8 ETS81568.1 - 2.2e-13 50.6 2.7 3.4e-08 34.0 0.0 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Serglycin PF04360.12 ETS81568.1 - 0.23 11.4 3.2 0.35 10.8 3.2 1.2 1 0 0 1 1 1 0 Serglycin ADH_zinc_N_2 PF13602.6 ETS81569.1 - 2.1e-26 93.5 0.0 3.9e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ETS81569.1 - 3.3e-15 56.2 0.3 7.3e-15 55.1 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS81569.1 - 1.1e-08 34.9 0.3 1.7e-06 27.9 0.0 3.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ETS81569.1 - 0.0051 16.7 0.8 0.029 14.3 0.1 2.7 3 1 0 3 3 3 1 N-terminal domain of oxidoreductase NifU_N PF01592.16 ETS81569.1 - 0.072 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 NifU-like N terminal domain Glyco_hydro_28 PF00295.17 ETS81570.1 - 5.4e-35 121.0 4.9 7.1e-35 120.6 4.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Cu-oxidase_3 PF07732.15 ETS81571.1 - 2.7e-46 156.5 4.5 9.8e-46 154.6 0.3 3.2 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ETS81571.1 - 2.8e-45 153.4 14.3 1.5e-40 138.1 0.7 4.4 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 ETS81571.1 - 1.5e-33 116.1 0.1 4.3e-33 114.7 0.1 1.8 1 0 0 1 1 1 1 Multicopper oxidase Peptidase_A4 PF01828.17 ETS81572.1 - 1.9e-51 174.5 15.8 3.1e-51 173.8 15.8 1.3 1 0 0 1 1 1 1 Peptidase A4 family Methyltransf_23 PF13489.6 ETS81573.1 - 6.3e-13 48.9 0.0 9.3e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS81573.1 - 4.8e-09 36.9 0.0 7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS81573.1 - 3.1e-07 31.0 0.0 7.2e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS81573.1 - 3.8e-06 27.5 0.0 1.2e-05 26.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS81573.1 - 0.00026 20.8 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS81573.1 - 0.021 14.2 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 ETS81573.1 - 0.023 13.9 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_28 PF02636.17 ETS81573.1 - 0.025 14.2 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.6 ETS81573.1 - 0.055 14.5 0.0 0.094 13.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 ETS81573.1 - 0.07 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase PRMT5 PF05185.16 ETS81573.1 - 0.18 11.7 0.0 0.23 11.3 0.0 1.1 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase AAA_16 PF13191.6 ETS81574.1 - 1e-06 29.3 0.2 1.2e-05 25.8 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain TPR_7 PF13176.6 ETS81574.1 - 1.3e-06 28.0 4.3 1.7 8.8 0.1 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 ETS81574.1 - 9.2e-05 22.2 9.3 0.05 13.5 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat AAA_22 PF13401.6 ETS81574.1 - 0.00011 22.4 2.7 0.0026 18.1 0.0 3.9 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 ETS81574.1 - 0.00019 21.4 0.0 0.00077 19.4 0.0 2.1 1 0 0 1 1 1 1 NACHT domain DOG1 PF14144.6 ETS81574.1 - 0.00041 20.5 0.4 0.4 10.9 0.0 4.7 3 0 0 3 3 3 1 Seed dormancy control TPR_19 PF14559.6 ETS81574.1 - 0.0037 17.7 7.1 12 6.5 0.1 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat AAA_26 PF13500.6 ETS81574.1 - 0.041 13.7 0.1 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain TPR_16 PF13432.6 ETS81574.1 - 0.041 14.5 0.1 31 5.3 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat Torsin PF06309.11 ETS81574.1 - 0.082 13.0 0.0 0.48 10.5 0.0 2.3 2 0 0 2 2 2 0 Torsin TPR_12 PF13424.6 ETS81574.1 - 1.2 9.5 26.2 3.3 8.1 0.0 7.7 8 1 0 8 8 7 0 Tetratricopeptide repeat AAA_19 PF13245.6 ETS81574.1 - 3.5 7.9 6.9 1.7 9.0 0.0 3.1 3 0 0 3 3 2 0 AAA domain Turandot PF07240.11 ETS81574.1 - 6 6.9 8.6 1.3 9.0 0.1 3.9 4 0 0 4 4 4 0 Stress-inducible humoral factor Turandot Glyco_hydro_106 PF17132.4 ETS81575.1 - 3.4e-19 68.6 0.0 9e-17 60.6 0.1 3.0 2 1 0 2 2 2 2 alpha-L-rhamnosidase Helo_like_N PF17111.5 ETS81576.1 - 3e-07 30.0 4.9 1.1e-06 28.2 2.8 2.3 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins FUSC PF04632.12 ETS81576.1 - 0.13 10.7 4.8 0.091 11.3 2.6 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family Glyco_hydro_39 PF01229.17 ETS81577.1 - 0.0002 20.1 0.5 0.0003 19.5 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Glyco_hydro_31 PF01055.26 ETS81578.1 - 6.9e-113 378.1 3.6 1e-112 377.6 3.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 ETS81578.1 - 7.7e-05 22.9 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 ETS81578.1 - 0.00018 21.8 1.9 0.0012 19.2 0.1 2.9 2 1 0 2 2 2 1 Galactose mutarotase-like DUF2188 PF09954.9 ETS81578.1 - 0.016 15.3 0.0 5.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Sugar_tr PF00083.24 ETS81579.1 - 3.2e-82 276.8 25.1 3.9e-82 276.5 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS81579.1 - 5.9e-20 71.5 30.4 5.9e-20 71.5 30.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2417 PF10329.9 ETS81579.1 - 0.016 14.7 0.2 0.31 10.4 0.0 2.4 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Holin_SPP1 PF04688.13 ETS81579.1 - 0.66 10.2 2.9 0.83 9.9 0.4 2.6 2 1 0 2 2 2 0 SPP1 phage holin P68HR PF08061.11 ETS81579.1 - 0.91 9.7 4.8 13 6.1 0.1 2.5 2 0 0 2 2 2 0 P68HR (NUC004) repeat Fungal_trans PF04082.18 ETS81580.1 - 7.7e-14 51.3 3.4 1.4e-13 50.5 3.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.23 ETS81581.1 - 1.2e-56 192.3 0.6 1.6e-56 192.0 0.6 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 ETS81581.1 - 0.0003 21.0 0.1 0.0025 18.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) SH3_18 PF18354.1 ETS81581.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 CarS bacterial SH3 domain ALAD PF00490.21 ETS81582.1 - 7.5e-121 403.2 0.0 8.9e-121 402.9 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase WD40 PF00400.32 ETS81583.1 - 2.1e-28 98.0 0.3 8.5e-08 32.7 0.0 6.3 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS81583.1 - 1.7e-13 50.6 0.0 0.00072 19.8 0.0 4.9 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ETS81583.1 - 0.0019 18.1 0.0 0.43 10.4 0.0 3.1 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 ETS81583.1 - 0.0098 15.5 0.1 0.074 12.6 0.1 2.2 1 1 0 1 1 1 1 PQQ-like domain PALB2_WD40 PF16756.5 ETS81583.1 - 0.018 14.0 0.1 1 8.2 0.0 2.3 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 ETS81583.1 - 0.036 12.7 0.1 0.088 11.4 0.0 1.6 2 1 0 2 2 2 0 Nucleoporin Nup120/160 SdiA-regulated PF06977.11 ETS81583.1 - 0.036 13.3 0.0 0.44 9.7 0.0 2.2 2 0 0 2 2 2 0 SdiA-regulated WD40_like PF17005.5 ETS81583.1 - 0.087 12.1 0.0 0.57 9.5 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain FTHFS PF01268.19 ETS81585.1 - 8.2e-255 846.2 0.2 1.2e-254 845.7 0.2 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 ETS81585.1 - 1.3e-67 226.1 1.1 1.3e-67 226.1 1.1 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 ETS81585.1 - 2.5e-38 130.9 0.2 6.5e-38 129.6 0.2 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 ETS81585.1 - 0.0033 16.4 0.1 0.0073 15.3 0.1 1.5 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Glyco_trans_1_4 PF13692.6 ETS81585.1 - 0.0087 16.5 0.0 0.052 14.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Helicase_C_4 PF13871.6 ETS81585.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue Zip PF02535.22 ETS81587.1 - 0.00077 18.8 1.2 0.00093 18.5 1.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter V_ATPase_I PF01496.19 ETS81587.1 - 0.0081 14.1 0.2 0.0091 14.0 0.2 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF913 PF06025.12 ETS81587.1 - 0.0092 15.0 1.9 0.01 14.9 1.9 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) SDA1 PF05285.12 ETS81587.1 - 0.01 15.3 39.9 0.012 15.1 39.9 1.0 1 0 0 1 1 1 0 SDA1 SID-1_RNA_chan PF13965.6 ETS81587.1 - 0.013 14.0 0.0 0.015 13.7 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SpoIIIAH PF12685.7 ETS81587.1 - 0.026 14.3 9.7 0.031 14.1 9.7 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Adipogenin PF15202.6 ETS81587.1 - 0.052 13.6 0.7 0.052 13.6 0.7 1.8 2 0 0 2 2 2 0 Adipogenin Connexin PF00029.19 ETS81587.1 - 0.14 11.9 2.0 0.22 11.3 2.0 1.3 1 1 0 1 1 1 0 Connexin RNA_pol_Rpc4 PF05132.14 ETS81587.1 - 0.2 12.1 5.3 0.24 11.8 5.3 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4637 PF15470.6 ETS81587.1 - 0.71 9.6 22.3 1.3 8.7 22.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Usp PF00582.26 ETS81587.1 - 0.76 10.3 6.5 1 9.9 6.5 1.2 1 0 0 1 1 1 0 Universal stress protein family Trypan_PARP PF05887.11 ETS81587.1 - 1.2 9.1 17.9 1.7 8.7 17.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Vfa1 PF08432.10 ETS81587.1 - 2.4 8.4 12.1 3.4 8.0 12.1 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Paf1 PF03985.13 ETS81587.1 - 2.7 6.9 25.8 3.6 6.5 25.8 1.1 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.12 ETS81587.1 - 2.7 6.1 48.0 3.3 5.8 48.0 1.0 1 0 0 1 1 1 0 Nop14-like family RNA_polI_A34 PF08208.11 ETS81587.1 - 3.5 7.7 14.2 4.4 7.3 14.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Merozoite_SPAM PF07133.11 ETS81587.1 - 5.2 7.0 44.4 6.5 6.7 44.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CPSF100_C PF13299.6 ETS81587.1 - 7.1 6.8 12.9 16 5.6 12.9 1.7 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2151 PF10221.9 ETS81587.1 - 7.3 5.1 8.1 8 4.9 8.1 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Tim54 PF11711.8 ETS81587.1 - 9.9 4.8 12.1 12 4.6 12.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Forkhead PF00250.18 ETS81588.1 - 4.3e-16 58.9 0.0 9.4e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 ETS81588.1 - 0.001 19.4 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain Voltage_CLC PF00654.20 ETS81589.1 - 0.0017 17.7 4.5 0.0022 17.3 4.5 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel DHHC PF01529.20 ETS81589.1 - 0.86 9.7 2.7 21 5.2 0.1 2.2 1 1 1 2 2 2 0 DHHC palmitoyltransferase MFS_MOT1 PF16983.5 ETS81590.1 - 4.1e-63 210.7 34.2 3.5e-34 117.5 10.0 2.5 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 ETS81590.1 - 9.9e-05 21.2 19.2 0.0026 16.6 19.1 2.3 1 1 0 1 1 1 1 Sulfate permease family p450 PF00067.22 ETS81591.1 - 1.1e-47 162.9 0.0 3.1e-47 161.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 PhoU PF01895.19 ETS81591.1 - 0.016 15.6 0.8 0.039 14.4 0.8 1.5 1 0 0 1 1 1 0 PhoU domain DNA_pol3_a_NII PF11490.8 ETS81591.1 - 0.09 12.7 0.4 0.22 11.4 0.4 1.6 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II DUF3405 PF11885.8 ETS81593.1 - 4.1e-208 692.2 3.8 4.1e-208 692.2 3.8 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3405) SpoIIIAH PF12685.7 ETS81593.1 - 0.00032 20.6 4.2 0.00049 20.0 4.2 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF3810 PF12725.7 ETS81593.1 - 0.041 13.2 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) CDC45 PF02724.14 ETS81593.1 - 0.053 11.8 5.1 0.069 11.4 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RP-C_C PF11800.8 ETS81593.1 - 0.22 11.6 3.1 0.42 10.7 3.1 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region RR_TM4-6 PF06459.12 ETS81593.1 - 2.1 8.1 11.7 3.4 7.4 11.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4366 PF14283.6 ETS81593.1 - 5.5 7.0 10.4 36 4.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) MFS_1 PF07690.16 ETS81594.1 - 3.3e-44 151.3 35.5 3.3e-44 151.3 35.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 ETS81594.1 - 0.019 13.3 8.0 0.0081 14.5 1.6 2.8 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PMP1_2 PF08114.11 ETS81594.1 - 4.1 7.2 6.5 1.1 9.0 0.3 2.9 3 0 0 3 3 3 0 ATPase proteolipid family Ribosomal_L44 PF00935.19 ETS81595.1 - 9.8e-37 125.3 11.5 1.6e-36 124.6 11.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 DNA_methylase PF00145.17 ETS81597.1 - 2.5e-16 60.0 0.1 1.4e-13 50.9 0.0 2.3 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase SNF2_N PF00176.23 ETS81598.1 - 1.2e-21 76.9 0.0 7.4e-16 57.8 0.0 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS81598.1 - 0.00095 19.5 0.7 0.01 16.2 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS81598.1 - 0.022 14.7 0.6 0.15 12.1 0.0 2.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit FliMN_C PF01052.20 ETS81598.1 - 0.048 13.7 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Type III flagellar switch regulator (C-ring) FliN C-term zf-RING_UBOX PF13445.6 ETS81598.1 - 0.36 10.9 3.3 1 9.4 3.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 ETS81598.1 - 1.4 8.8 5.0 3.2 7.7 5.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Ureidogly_lyase PF04115.12 ETS81599.1 - 4.1e-55 186.5 0.0 4.9e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase GAS PF13851.6 ETS81602.1 - 0.0023 17.3 8.5 0.0037 16.6 8.5 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Rootletin PF15035.6 ETS81602.1 - 0.0077 16.3 3.7 0.012 15.6 3.7 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DUF1664 PF07889.12 ETS81602.1 - 0.033 14.2 1.5 0.048 13.7 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 ETS81602.1 - 0.046 13.7 3.3 0.068 13.2 2.3 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding KxDL PF10241.9 ETS81602.1 - 0.049 13.9 1.0 0.11 12.7 0.7 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein DUF3552 PF12072.8 ETS81602.1 - 0.052 13.0 10.7 0.13 11.6 10.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Spc7 PF08317.11 ETS81602.1 - 0.056 12.3 9.9 0.077 11.9 9.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein bZIP_2 PF07716.15 ETS81602.1 - 0.057 13.5 0.6 0.057 13.5 0.6 3.0 2 1 1 3 3 3 0 Basic region leucine zipper Atg14 PF10186.9 ETS81602.1 - 0.086 11.9 2.8 0.14 11.2 2.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0449 PF15136.6 ETS81602.1 - 0.089 13.3 5.2 1.4 9.4 1.4 2.6 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 CLZ PF16526.5 ETS81602.1 - 0.12 12.8 2.5 0.37 11.2 2.5 1.9 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 ETS81602.1 - 0.13 12.6 3.5 0.4 11.0 3.5 1.8 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HSBP1 PF06825.12 ETS81602.1 - 0.17 11.7 0.6 0.37 10.7 0.1 1.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF1759 PF03564.15 ETS81602.1 - 0.18 11.8 1.0 0.3 11.0 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Syntaxin-6_N PF09177.11 ETS81602.1 - 0.21 12.1 3.4 0.49 11.0 3.4 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal PilJ PF13675.6 ETS81602.1 - 0.22 11.5 2.2 0.2 11.7 0.4 1.8 2 0 0 2 2 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term bZIP_1 PF00170.21 ETS81602.1 - 0.3 11.2 6.3 0.39 10.9 1.3 3.0 2 1 1 3 3 3 0 bZIP transcription factor CorA PF01544.18 ETS81602.1 - 1.9 7.7 4.7 2.9 7.1 4.7 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2630 PF10944.8 ETS81602.1 - 2.3 8.8 7.3 0.74 10.3 4.0 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF2630) ATG16 PF08614.11 ETS81602.1 - 5 7.3 14.3 37 4.5 14.3 2.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) NBP1 PF08537.10 ETS81602.1 - 5.1 6.4 10.1 0.61 9.4 4.0 1.9 1 1 1 2 2 2 0 Fungal Nap binding protein NBP1 ZapB PF06005.12 ETS81602.1 - 5.2 7.6 8.3 1.9 9.0 3.9 2.5 1 1 2 3 3 3 0 Cell division protein ZapB MFS_1 PF07690.16 ETS81604.1 - 4.4e-08 32.4 40.6 5.9e-06 25.4 20.3 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS81605.1 - 4e-121 405.0 25.1 4.6e-121 404.8 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS81605.1 - 3.8e-20 72.1 39.2 2.1e-14 53.2 14.8 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF998 PF06197.13 ETS81605.1 - 5.5 6.5 21.9 0.21 11.2 7.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF998) Fungal_trans_2 PF11951.8 ETS81606.1 - 2.8e-09 36.3 2.2 7.2e-09 34.9 2.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Patatin PF01734.22 ETS81607.1 - 1.6e-15 57.8 0.0 3.2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Sugar_tr PF00083.24 ETS81608.1 - 1.3e-111 373.6 19.8 1.6e-111 373.4 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS81608.1 - 7.8e-23 81.0 25.8 7.8e-23 81.0 25.8 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS81608.1 - 0.0012 17.3 1.0 0.0022 16.5 1.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) zf-C2H2 PF00096.26 ETS81609.1 - 0.00036 20.8 13.6 0.13 12.7 0.6 4.3 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS81609.1 - 0.021 15.6 17.4 0.13 13.2 0.6 5.0 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ETS81609.1 - 0.035 14.4 1.4 9.1 6.7 0.1 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding BAT PF15915.5 ETS81609.1 - 0.067 13.1 1.3 4.1 7.3 0.1 2.5 2 0 0 2 2 2 0 GAF and HTH_10 associated domain Sina PF03145.16 ETS81609.1 - 0.078 12.9 1.3 0.15 12.0 1.3 1.4 1 0 0 1 1 1 0 Seven in absentia protein family Glyco_hydro_43 PF04616.14 ETS81610.1 - 9.8e-20 71.0 5.4 1.7e-19 70.3 5.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 HET-s_218-289 PF11558.8 ETS81610.1 - 0.011 15.7 0.1 0.38 10.8 0.1 2.6 2 0 0 2 2 2 0 Het-s 218-289 Glyco_hydro_31 PF01055.26 ETS81611.1 - 3.7e-153 510.9 4.6 4.7e-153 510.5 4.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 ETS81611.1 - 4.2e-38 130.1 0.0 8.6e-38 129.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 ETS81611.1 - 6.2e-13 48.9 0.7 6.2e-13 48.9 0.7 2.6 3 0 0 3 3 3 1 Galactose mutarotase-like Sugar_tr PF00083.24 ETS81612.1 - 2.7e-108 362.7 31.4 3.2e-108 362.5 31.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS81612.1 - 9.5e-24 84.0 31.1 9.5e-24 84.0 31.1 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily Proton_antipo_N PF00662.20 ETS81612.1 - 0.1 12.7 3.0 0.22 11.6 0.7 2.7 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DUF1799 PF08809.11 ETS81612.1 - 1.1 9.4 3.8 26 5.1 0.2 2.8 3 0 0 3 3 3 0 Phage related hypothetical protein (DUF1799) DUF3302 PF11742.8 ETS81612.1 - 3.7 7.8 7.8 1.8 8.7 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3302) Zn_clus PF00172.18 ETS81613.1 - 3.6e-16 59.0 25.8 6.1e-10 39.1 7.3 3.3 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS81613.1 - 6.9e-16 58.1 0.2 1.2e-15 57.3 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain LINES_C PF14695.6 ETS81614.1 - 0.13 11.7 0.1 0.25 10.8 0.1 1.5 1 0 0 1 1 1 0 Lines C-terminus Sulfatase PF00884.23 ETS81615.1 - 8.4e-77 258.6 0.0 1e-76 258.3 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 ETS81615.1 - 0.043 13.4 0.0 1.4 8.4 0.0 2.5 3 0 0 3 3 3 0 Type I phosphodiesterase / nucleotide pyrophosphatase SNARE PF05739.19 ETS81615.1 - 0.051 13.6 0.1 0.092 12.8 0.1 1.3 1 0 0 1 1 1 0 SNARE domain DUF229 PF02995.17 ETS81615.1 - 0.11 11.1 0.0 0.19 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DEAD PF00270.29 ETS81616.1 - 7.7e-48 162.6 0.2 2.6e-45 154.3 0.1 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS81616.1 - 1.9e-23 82.9 0.0 1.8e-20 73.3 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 ETS81616.1 - 1.7e-07 31.4 0.0 3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pec_lyase_C PF00544.19 ETS81617.1 - 4.5e-16 59.1 9.1 1.5e-14 54.1 9.0 2.4 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 ETS81617.1 - 4.9e-06 26.5 9.9 0.013 15.4 2.9 2.4 1 1 1 2 2 2 2 Right handed beta helix region PPR_2 PF13041.6 ETS81618.1 - 1.5e-09 37.9 0.9 2.4 8.4 0.0 6.9 6 1 1 7 7 7 3 PPR repeat family PPR PF01535.20 ETS81618.1 - 8.2e-07 28.9 2.6 8.6 6.9 0.0 7.5 9 0 0 9 9 9 2 PPR repeat PPR_long PF17177.4 ETS81618.1 - 3.5e-06 26.5 0.0 0.0012 18.3 0.0 3.7 3 1 1 4 4 4 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 ETS81618.1 - 5.9e-06 26.3 0.1 0.0074 16.3 0.0 3.9 4 0 0 4 4 4 1 Pentatricopeptide repeat domain Clathrin PF00637.20 ETS81618.1 - 0.016 15.0 0.3 0.97 9.3 0.0 3.6 4 0 0 4 4 4 0 Region in Clathrin and VPS ATP13 PF12921.7 ETS81618.1 - 0.11 12.4 0.0 2.2 8.2 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ATPase expression Ribosomal_S18 PF01084.20 ETS81619.1 - 3.2e-11 43.3 0.1 7.3e-11 42.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S18 APT PF03440.14 ETS81619.1 - 0.076 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Aerolysin/Pertussis toxin (APT) domain S4 PF01479.25 ETS81620.1 - 6.5e-13 48.2 0.0 1.4e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 ETS81620.1 - 1.1e-11 45.5 0.7 1.8e-11 44.8 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain THDPS_N_2 PF14805.6 ETS81620.1 - 0.04 14.2 0.0 0.07 13.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal SNF2_N PF00176.23 ETS81621.1 - 3.6e-49 167.4 0.1 5.6e-49 166.7 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 ETS81621.1 - 4.2e-23 81.2 1.6 1.1e-22 79.9 1.6 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 ETS81621.1 - 2.7e-21 76.0 0.0 5.8e-20 71.7 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS81621.1 - 5.3e-08 33.1 0.0 1e-06 28.8 0.0 2.9 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ETS81621.1 - 3.7e-07 29.6 0.0 6.8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 ETS81621.1 - 0.0046 16.8 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ank_3 PF13606.6 ETS81622.1 - 0.0008 19.7 0.0 0.076 13.6 0.0 4.0 3 1 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 ETS81622.1 - 0.0083 16.7 0.0 0.092 13.3 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) DUF1173 PF06666.11 ETS81622.1 - 0.011 14.6 0.2 0.025 13.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) Ank_4 PF13637.6 ETS81622.1 - 0.028 15.0 0.0 16 6.2 0.0 3.7 2 1 1 3 3 3 0 Ankyrin repeats (many copies) TMF_TATA_bd PF12325.8 ETS81622.1 - 0.058 13.6 5.2 5.2 7.3 0.3 3.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Helo_like_N PF17111.5 ETS81622.1 - 0.26 10.6 2.0 1.1 8.6 0.1 2.8 1 1 2 3 3 3 0 Fungal N-terminal domain of STAND proteins DUF16 PF01519.16 ETS81622.1 - 0.33 11.5 2.0 14 6.2 0.0 3.8 4 1 0 4 4 4 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 ETS81622.1 - 0.89 9.6 20.2 43 4.1 0.3 4.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus COMM_domain PF07258.14 ETS81622.1 - 1.5 9.0 4.1 1.6 8.9 0.6 2.7 2 0 0 2 2 2 0 COMM domain AA_permease_2 PF13520.6 ETS81623.1 - 1.6e-56 192.0 33.0 2e-56 191.6 33.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS81623.1 - 2.1e-21 76.1 32.4 4.5e-20 71.7 24.2 2.2 2 0 0 2 2 2 2 Amino acid permease NADHdeh_related PF10125.9 ETS81623.1 - 0.77 9.1 11.5 0.036 13.4 5.5 1.8 2 0 0 2 2 2 0 NADH dehydrogenase I, subunit N related protein Abhydrolase_3 PF07859.13 ETS81625.1 - 9.1e-39 133.5 0.0 1.1e-38 133.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 ETS81625.1 - 2e-08 34.1 0.0 0.00028 20.5 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 ETS81625.1 - 7.8e-06 25.5 0.0 0.005 16.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF2974 PF11187.8 ETS81625.1 - 0.00063 19.4 0.0 0.00093 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 ETS81625.1 - 0.00076 18.8 0.1 0.87 8.8 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS81625.1 - 0.0024 18.5 0.2 0.0035 18.0 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 ETS81625.1 - 0.0096 15.9 0.0 0.027 14.4 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 ETS81625.1 - 0.015 15.1 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 ETS81625.1 - 0.034 14.2 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 ETS81625.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Kinesin PF00225.23 ETS81627.1 - 5.9e-110 367.3 0.5 1.4e-109 366.1 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.8 ETS81627.1 - 3.5e-49 167.4 0.3 1.3e-48 165.5 0.0 2.1 2 0 0 2 2 2 1 Kinesin protein Kinesin_assoc PF16183.5 ETS81627.1 - 1e-35 123.6 16.1 9.7e-32 110.6 0.4 4.0 3 1 1 4 4 4 2 Kinesin-associated Microtub_bd PF16796.5 ETS81627.1 - 1.7e-24 86.5 0.0 3.9e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 ETS81627.1 - 1.7e-06 28.4 0.9 1.7e-06 28.4 0.9 2.3 2 0 0 2 2 2 1 Kinesin protein 1B PH PF00169.29 ETS81627.1 - 0.005 17.3 0.0 0.036 14.6 0.0 2.4 1 1 0 1 1 1 1 PH domain Yop-YscD_cpl PF16697.5 ETS81627.1 - 0.087 13.1 0.0 0.34 11.3 0.0 2.0 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain UPF0242 PF06785.11 ETS81627.1 - 1.7 8.7 14.0 9.2 6.3 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus p450 PF00067.22 ETS81628.1 - 6.8e-53 180.0 0.0 8.3e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SKG6 PF08693.10 ETS81629.1 - 1.9e-05 24.0 1.1 3.9e-05 23.0 1.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Fungal_lectin PF07938.12 ETS81629.1 - 0.0034 16.8 12.0 0.0078 15.6 0.9 2.9 3 1 0 3 3 3 2 Fungal fucose-specific lectin Rax2 PF12768.7 ETS81629.1 - 0.015 14.7 0.7 0.2 11.1 0.0 2.2 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Podoplanin PF05808.11 ETS81629.1 - 0.02 15.0 0.1 0.038 14.1 0.1 1.4 1 0 0 1 1 1 0 Podoplanin STALD PF18185.1 ETS81629.1 - 0.07 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family FeoB_associated PF12669.7 ETS81629.1 - 0.15 12.4 0.2 0.28 11.6 0.2 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein NAD_binding_1 PF00175.21 ETS81630.1 - 2.1e-25 89.5 0.0 3.1e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ETS81630.1 - 5.9e-16 58.6 0.0 8.6e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ETS81630.1 - 0.00031 20.9 0.1 0.23 11.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Peptidase_C48 PF02902.19 ETS81631.1 - 0.091 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain DUF1279 PF06916.13 ETS81632.1 - 8.1e-25 87.2 0.0 1.5e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF3390 PF11870.8 ETS81632.1 - 0.03 14.7 0.3 0.15 12.5 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3390) DUF3619 PF12279.8 ETS81632.1 - 1.3 9.4 4.0 1.3 9.3 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3619) Sel_put PF04328.13 ETS81633.1 - 0.66 10.1 4.2 1.4 9.0 0.1 2.4 2 0 0 2 2 2 0 Selenoprotein, putative Lipase_GDSL_2 PF13472.6 ETS81634.1 - 1.6e-14 54.7 1.6 2.3e-14 54.2 1.6 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS81634.1 - 4.6e-10 39.8 0.4 7.9e-10 39.0 0.4 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 ETS81634.1 - 0.00095 19.3 0.1 0.0021 18.2 0.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Sedlin_N PF04628.13 ETS81635.1 - 4.8e-12 46.1 0.0 6.8e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 ETS81635.1 - 0.2 11.6 0.0 5.8 6.8 0.0 2.1 2 0 0 2 2 2 0 Sybindin-like family Acyl_transf_1 PF00698.21 ETS81636.1 - 6.6e-22 78.4 1.6 7.5e-14 52.0 0.1 2.1 2 0 0 2 2 2 2 Acyl transferase domain Adap_comp_sub PF00928.21 ETS81637.1 - 2.6e-68 230.3 0.0 3.2e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ETS81637.1 - 3.5e-05 23.8 0.0 5.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mpp10 PF04006.12 ETS81638.1 - 6.5e-113 378.3 56.0 8.1e-111 371.4 56.0 2.4 1 1 0 1 1 1 1 Mpp10 protein BAR PF03114.18 ETS81638.1 - 0.017 14.7 0.6 0.058 13.0 0.6 1.9 1 0 0 1 1 1 0 BAR domain DUF4536 PF15055.6 ETS81639.1 - 7.2e-07 29.3 4.1 9.1e-07 29.0 0.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4536) DUF922 PF06037.11 ETS81640.1 - 0.025 14.4 0.3 0.041 13.7 0.3 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) Pkinase PF00069.25 ETS81641.1 - 2.5e-51 174.6 0.0 3.5e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS81641.1 - 2.3e-18 66.4 0.0 4.5e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ETS81641.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETS81641.1 - 0.057 13.0 0.7 0.12 12.0 0.7 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 ETS81641.1 - 0.13 11.9 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 RIO1 family CDH-cyt PF16010.5 ETS81642.1 - 2.2e-22 79.7 0.0 3.6e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 ETS81642.1 - 8.5e-10 38.9 10.2 8.5e-10 38.9 10.2 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 ETS81642.1 - 5.2e-05 23.0 2.6 5.2e-05 23.0 2.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF1673 PF07895.11 ETS81642.1 - 0.0049 16.6 2.5 0.0084 15.8 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1673) SARAF PF06682.12 ETS81642.1 - 0.01 15.5 0.5 0.019 14.6 0.2 1.5 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Rubredoxin_2 PF18073.1 ETS81642.1 - 0.046 13.4 0.3 0.12 12.2 0.3 1.6 1 0 0 1 1 1 0 Rubredoxin metal binding domain DUF4191 PF13829.6 ETS81642.1 - 0.06 12.7 1.1 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) ISK_Channel PF02060.15 ETS81642.1 - 0.12 12.0 0.7 6.1 6.6 0.0 2.6 2 0 0 2 2 2 0 Slow voltage-gated potassium channel TssN PF17555.2 ETS81642.1 - 2 7.8 5.2 1.8 7.9 4.1 1.4 1 1 0 1 1 1 0 Type VI secretion system, TssN Ni_hydr_CYTB PF01292.20 ETS81642.1 - 2.2 7.9 11.5 6.8 6.2 11.5 2.0 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF1772 PF08592.11 ETS81642.1 - 2.9 8.2 6.4 17 5.8 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) DUF2157 PF09925.9 ETS81642.1 - 5.3 6.8 7.6 16 5.3 7.6 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) Amidase PF01425.21 ETS81644.1 - 5.6e-94 315.6 0.0 1.1e-93 314.7 0.0 1.4 1 1 0 1 1 1 1 Amidase p450 PF00067.22 ETS81645.1 - 1.5e-55 188.8 0.0 1.9e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.13 ETS81646.1 - 1.6e-46 158.8 3.4 1.1e-45 156.1 3.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS81646.1 - 0.00016 21.2 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 ETS81646.1 - 0.00031 19.8 0.0 0.0028 16.6 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.7 ETS81646.1 - 0.0017 19.0 0.5 0.0033 18.0 0.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 ETS81646.1 - 0.022 14.3 0.3 0.09 12.3 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family Ank_4 PF13637.6 ETS81647.1 - 1.1e-12 48.1 1.1 1.4e-06 28.7 0.1 4.9 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS81647.1 - 8.7e-12 45.5 0.1 1.7e-08 35.0 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) NACHT PF05729.12 ETS81647.1 - 1.1e-10 41.7 0.0 1e-08 35.3 0.0 3.0 2 1 0 2 2 2 1 NACHT domain Ank_5 PF13857.6 ETS81647.1 - 1.3e-10 41.3 0.5 0.00015 22.0 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS81647.1 - 1.1e-08 35.2 0.5 1.8e-05 24.9 0.0 4.2 3 1 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 ETS81647.1 - 1.6e-07 31.0 0.0 0.0063 16.9 0.0 4.3 4 0 0 4 4 3 1 Ankyrin repeat AAA_16 PF13191.6 ETS81647.1 - 3.3e-06 27.6 0.4 5.3e-05 23.7 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS81647.1 - 0.00019 21.7 0.9 0.017 15.4 0.1 3.2 2 1 1 3 3 2 1 AAA domain DUF676 PF05057.14 ETS81647.1 - 0.0024 17.4 0.0 0.09 12.3 0.0 2.4 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 ETS81647.1 - 0.0089 15.7 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 ETS81647.1 - 0.0096 15.7 0.0 0.051 13.3 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein AAA_30 PF13604.6 ETS81647.1 - 0.02 14.6 0.1 0.046 13.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ETS81647.1 - 0.024 14.4 0.9 0.17 11.6 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Abhydrolase_6 PF12697.7 ETS81647.1 - 0.032 14.8 0.0 0.098 13.2 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family KAP_NTPase PF07693.14 ETS81647.1 - 0.046 12.9 1.3 1.2 8.3 0.0 2.2 1 1 0 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.22 ETS81647.1 - 0.058 12.6 1.1 0.19 10.9 0.1 2.2 3 0 0 3 3 3 0 NB-ARC domain RNA_helicase PF00910.22 ETS81647.1 - 0.073 13.5 0.4 0.21 12.0 0.1 2.0 2 0 0 2 2 1 0 RNA helicase ATPase_2 PF01637.18 ETS81647.1 - 0.095 12.6 0.0 0.67 9.8 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 ETS81647.1 - 0.17 12.1 0.2 4 7.6 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ETS81647.1 - 0.29 11.7 0.9 4.1 8.0 0.1 2.9 2 0 0 2 2 2 0 AAA domain MARVEL PF01284.23 ETS81648.1 - 2.9e-26 92.2 18.7 3.6e-26 91.9 18.7 1.0 1 0 0 1 1 1 1 Membrane-associating domain MpPF26 PF07666.11 ETS81648.1 - 2.3 8.4 10.7 9.4 6.4 7.9 2.7 2 1 0 2 2 2 0 M penetrans paralogue family 26 COQ7 PF03232.13 ETS81649.1 - 3.3e-72 241.8 0.7 4e-72 241.6 0.7 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 ETS81649.1 - 0.00021 21.7 0.0 0.00058 20.3 0.0 1.7 1 1 0 1 1 1 1 Rubrerythrin Sld5 PF05916.11 ETS81649.1 - 0.059 13.8 0.2 0.15 12.5 0.2 1.5 1 1 0 1 1 1 0 GINS complex protein DUF724 PF05266.14 ETS81649.1 - 0.23 11.3 1.2 0.24 11.2 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Plus-3 PF03126.18 ETS81650.1 - 4e-30 104.5 0.0 8.5e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain Fungal_trans PF04082.18 ETS81652.1 - 3.2e-06 26.4 0.6 0.0002 20.5 0.2 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain HET PF06985.11 ETS81653.1 - 1.7e-22 80.4 0.0 2.9e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Amidohydro_2 PF04909.14 ETS81654.1 - 2.7e-24 86.5 0.2 3.8e-24 86.0 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase IDO PF01231.18 ETS81655.1 - 6.2e-33 114.2 0.0 7.7e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase But2 PF09792.9 ETS81656.1 - 6.7e-07 29.8 0.7 1.7e-06 28.5 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Nop14 PF04147.12 ETS81656.1 - 0.081 11.1 10.7 0.098 10.9 10.7 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 ETS81656.1 - 0.22 10.6 13.4 0.28 10.3 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 ETS81656.1 - 1.1 8.6 11.9 1.5 8.2 11.9 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 ETS81656.1 - 2.3 7.4 11.5 3.1 7.0 11.5 1.1 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 ETS81656.1 - 4.6 5.6 13.3 6.2 5.1 13.3 1.1 1 0 0 1 1 1 0 Mpp10 protein OB_NTP_bind PF07717.16 ETS81657.1 - 1.5e-21 76.5 0.0 3.5e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 ETS81657.1 - 1.7e-19 70.1 0.1 1.7e-19 70.1 0.1 4.3 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ETS81657.1 - 4.7e-14 52.7 0.0 1.4e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ETS81657.1 - 2.8e-06 27.2 0.0 6.3e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ETS81657.1 - 2.5e-05 24.6 0.2 9.7e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ETS81657.1 - 0.0011 18.7 0.0 0.0011 18.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 ETS81657.1 - 0.0013 17.9 0.0 0.0031 16.6 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 ETS81657.1 - 0.0047 17.3 0.6 0.012 15.9 0.1 1.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 ETS81657.1 - 0.032 13.9 0.2 0.078 12.6 0.2 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 ETS81657.1 - 0.042 14.4 1.0 0.14 12.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter PhoH PF02562.16 ETS81657.1 - 0.079 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.6 ETS81657.1 - 0.15 12.5 0.0 0.15 12.5 0.0 3.4 1 1 0 2 2 1 0 AAA domain AAA_14 PF13173.6 ETS81657.1 - 0.56 10.2 4.0 5.1 7.1 0.2 3.4 2 1 0 2 2 2 0 AAA domain DnaJ_C PF01556.18 ETS81658.1 - 1.2e-24 87.1 0.0 1.8e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ETS81658.1 - 9.8e-23 80.1 1.1 9.8e-23 80.1 1.1 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ETS81658.1 - 8.9e-13 48.4 17.4 1.4e-12 47.8 17.4 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 ETS81658.1 - 0.00014 21.8 6.8 0.062 13.3 1.0 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 ETS81658.1 - 0.0011 18.9 10.4 0.017 15.1 1.0 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 ETS81658.1 - 0.052 13.2 3.2 1.2 8.7 0.2 2.4 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 ETS81658.1 - 2.8 8.0 11.7 31 4.7 11.7 2.2 1 1 0 1 1 1 0 Double zinc ribbon Lar_restr_allev PF14354.6 ETS81658.1 - 6 7.3 12.3 8.4 6.9 2.0 3.5 1 1 2 3 3 3 0 Restriction alleviation protein Lar Methyltransf_23 PF13489.6 ETS81659.1 - 4.5e-08 33.1 0.0 6.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS81659.1 - 1e-06 29.3 0.0 1.9e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS81659.1 - 1.8e-05 25.4 0.0 2.9e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS81659.1 - 8.5e-05 23.2 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS81659.1 - 0.0041 16.9 0.0 0.0068 16.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS81659.1 - 0.085 12.2 0.0 0.16 11.2 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Pyr_redox_2 PF07992.14 ETS81660.1 - 3.2e-11 43.0 0.1 3.6e-08 33.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS81660.1 - 0.00097 18.8 1.4 0.007 16.0 0.5 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS81660.1 - 0.003 17.8 0.3 0.0093 16.2 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS81660.1 - 0.0052 16.8 0.1 0.021 14.8 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 ETS81660.1 - 0.022 13.6 1.4 0.029 13.2 0.1 1.8 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.12 ETS81660.1 - 0.048 12.7 0.1 0.077 12.0 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Malic_M PF03949.15 ETS81660.1 - 0.19 10.9 0.6 0.32 10.2 0.6 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain SPX PF03105.19 ETS81661.1 - 3.1e-11 43.8 15.4 6.9e-05 22.9 0.2 4.0 2 1 2 4 4 4 3 SPX domain YdjM PF04307.14 ETS81661.1 - 0.036 13.4 0.3 0.059 12.7 0.3 1.3 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase DUF3627 PF12299.8 ETS81661.1 - 0.19 11.8 0.1 0.44 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) FtsX PF02687.21 ETS81661.1 - 0.88 10.1 5.3 1.5 9.3 5.3 1.3 1 0 0 1 1 1 0 FtsX-like permease family RhgB_N PF09284.10 ETS81662.1 - 6.5e-94 314.1 9.4 1.1e-93 313.4 9.4 1.4 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 ETS81662.1 - 1.6e-33 115.9 0.1 6.2e-33 114.0 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 ETS81662.1 - 2.1e-19 69.0 6.4 2.1e-19 69.0 6.4 3.2 3 1 0 3 3 3 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 ETS81662.1 - 0.00061 20.0 2.3 0.00061 20.0 2.3 3.4 4 0 0 4 4 4 1 Carboxypeptidase regulatory-like domain Glyco_hydro_10 PF00331.20 ETS81664.1 - 8.1e-89 297.9 0.0 9.2e-89 297.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 zf-MYND PF01753.18 ETS81665.1 - 9.2e-11 41.7 17.6 1.6e-10 40.9 17.6 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ETS81665.1 - 0.048 14.0 10.5 0.14 12.4 10.5 1.8 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding UDPGT PF00201.18 ETS81666.1 - 1.1e-10 40.9 0.1 2.8e-10 39.6 0.2 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ETS81666.1 - 0.00051 20.1 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Ribosomal_S9 PF00380.19 ETS81666.1 - 0.082 13.4 0.1 0.24 12.0 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein S9/S16 Lipase_GDSL PF00657.22 ETS81667.1 - 1.7e-08 34.7 0.1 2.2e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ETS81667.1 - 1.1e-05 25.9 0.9 4.9e-05 23.8 0.9 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Fungal_trans PF04082.18 ETS81668.1 - 1.6e-09 37.2 0.4 2.9e-09 36.4 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 ETS81669.1 - 5.9e-19 68.3 0.4 3.2e-15 56.1 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 ETS81669.1 - 6.5e-06 26.2 0.3 1.2e-05 25.4 0.3 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ETS81669.1 - 2.5e-05 24.0 0.3 0.00015 21.4 0.1 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Herpes_UL6 PF01763.16 ETS81670.1 - 0.059 11.9 0.1 0.079 11.5 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Nup88 PF10168.9 ETS81670.1 - 1.3 6.8 6.2 1.6 6.4 6.2 1.0 1 0 0 1 1 1 0 Nuclear pore component LOH1CR12 PF10158.9 ETS81671.1 - 3.9 7.5 7.5 7 6.7 0.1 2.8 2 1 1 3 3 3 0 Tumour suppressor protein WD40 PF00400.32 ETS81672.1 - 1.2e-14 54.4 10.4 6.5e-06 26.8 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS81672.1 - 4.6e-05 23.6 0.0 0.29 11.5 0.0 4.2 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 ETS81672.1 - 0.0016 18.1 0.0 0.019 14.6 0.0 2.4 1 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region PUL PF08324.11 ETS81673.1 - 4.6e-59 199.9 0.0 7.1e-59 199.3 0.0 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 ETS81673.1 - 7.4e-43 145.4 0.3 1.6e-42 144.4 0.3 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 ETS81673.1 - 1.2e-31 108.3 6.3 3.1e-05 24.6 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Glyco_hydro_49N PF17433.2 ETS81673.1 - 0.0097 15.6 0.3 0.018 14.7 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 N-terminal Ig-like domain BBS2_Mid PF14783.6 ETS81673.1 - 0.077 13.0 0.0 4.5 7.4 0.0 2.9 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region SRR1 PF07985.12 ETS81675.1 - 6.6e-18 64.5 0.1 1.2e-17 63.7 0.1 1.4 1 0 0 1 1 1 1 SRR1 PhyH PF05721.13 ETS81676.1 - 2.4e-07 31.2 0.0 6.7e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 ETS81676.1 - 1.1e-05 24.5 0.0 0.01 14.7 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 ETS81676.1 - 0.013 15.9 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 ETS81676.1 - 0.11 13.4 0.0 0.23 12.4 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily VIT PF08487.10 ETS81677.1 - 1.9e-35 121.4 0.0 4.5e-35 120.2 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 ETS81677.1 - 1.2e-27 96.7 0.0 2.5e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 ETS81677.1 - 3.5e-15 55.7 0.0 7.2e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 ETS81677.1 - 9.5e-09 35.7 0.0 1.7e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 ETS81677.1 - 5.4e-08 33.5 0.0 1.9e-07 31.7 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 ETS81677.1 - 0.0058 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Glyco_hydro_92 PF07971.12 ETS81678.1 - 3.3e-147 491.1 0.3 4e-147 490.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 ETS81678.1 - 7e-57 193.1 1.4 1.3e-56 192.2 1.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Gln-synt_N PF03951.19 ETS81678.1 - 0.088 12.5 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain HRI1 PF16815.5 ETS81679.1 - 3e-69 233.2 4.5 3.4e-69 233.1 4.5 1.0 1 0 0 1 1 1 1 Protein HRI1 p450 PF00067.22 ETS81680.1 - 2.1e-40 138.8 0.0 1.7e-39 135.9 0.0 1.9 1 1 0 2 2 2 2 Cytochrome P450 Fungal_trans_2 PF11951.8 ETS81681.1 - 1.3e-27 96.6 8.9 1.6e-26 93.0 8.9 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_2 PF13639.6 ETS81682.1 - 4.3e-09 36.6 4.9 4.3e-09 36.6 4.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 ETS81682.1 - 0.00033 20.6 2.2 0.00033 20.6 2.2 2.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 ETS81682.1 - 0.00061 19.8 2.5 0.00061 19.8 2.5 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.6 ETS81682.1 - 0.0011 18.9 2.7 0.0011 18.9 2.7 3.3 2 1 1 3 3 3 2 Prokaryotic RING finger family 1 PHD PF00628.29 ETS81682.1 - 0.0016 18.3 5.6 0.0038 17.1 5.6 1.7 1 0 0 1 1 1 1 PHD-finger zf-rbx1 PF12678.7 ETS81682.1 - 0.0025 18.0 4.2 0.0025 18.0 4.2 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain FANCL_C PF11793.8 ETS81682.1 - 0.0034 17.5 5.3 0.0034 17.5 5.3 2.1 2 1 0 2 2 2 1 FANCL C-terminal domain RINGv PF12906.7 ETS81682.1 - 0.025 14.7 5.4 0.064 13.4 5.4 1.7 1 0 0 1 1 1 0 RING-variant domain FYVE PF01363.21 ETS81682.1 - 0.033 14.3 3.3 0.078 13.1 3.3 1.7 1 0 0 1 1 1 0 FYVE zinc finger Pellino PF04710.14 ETS81682.1 - 0.044 12.5 0.2 0.09 11.4 0.2 1.5 1 0 0 1 1 1 0 Pellino SWIM PF04434.17 ETS81682.1 - 0.057 13.1 2.3 0.12 12.1 2.3 1.6 1 0 0 1 1 1 0 SWIM zinc finger Zf_RING PF16744.5 ETS81682.1 - 0.1 12.7 3.4 0.28 11.3 3.4 1.8 1 1 0 1 1 1 0 KIAA1045 RING finger zf-RING_4 PF14570.6 ETS81682.1 - 9.9 6.1 14.0 0.3 10.9 7.3 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Glyco_hydro_28 PF00295.17 ETS81683.1 - 1.9e-107 359.1 21.9 2.4e-107 358.8 21.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 LtuA PF17446.2 ETS81684.1 - 0.045 14.2 0.1 0.085 13.3 0.1 1.4 1 0 0 1 1 1 0 Late transcription unit A SnoaL_2 PF12680.7 ETS81684.1 - 0.064 13.9 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain Ferritin_2 PF13668.6 ETS81685.1 - 6.3e-17 62.1 0.0 1.4e-16 60.9 0.0 1.6 2 0 0 2 2 2 1 Ferritin-like domain CYYR1 PF10873.8 ETS81685.1 - 1 9.8 5.6 0.36 11.3 2.6 1.7 1 1 1 2 2 2 0 Cysteine and tyrosine-rich protein 1 WD40 PF00400.32 ETS81686.1 - 4.7e-08 33.6 7.5 1.1 10.3 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat CDC45 PF02724.14 ETS81686.1 - 0.064 11.5 14.1 0.085 11.1 14.1 1.1 1 0 0 1 1 1 0 CDC45-like protein F-box PF00646.33 ETS81688.1 - 0.00066 19.5 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ETS81688.1 - 0.05 13.5 0.7 0.32 10.9 0.0 2.5 3 0 0 3 3 3 0 F-box-like Pex19 PF04614.12 ETS81689.1 - 7e-70 235.6 15.5 7e-70 235.6 15.5 1.8 2 0 0 2 2 2 1 Pex19 protein family GlutR_dimer PF00745.20 ETS81689.1 - 0.082 13.4 2.0 0.16 12.4 0.2 2.4 2 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Nudix_N PF12535.8 ETS81689.1 - 0.1 12.2 0.4 0.86 9.3 0.1 2.6 2 0 0 2 2 2 0 Hydrolase of X-linked nucleoside diphosphate N terminal DUF4407 PF14362.6 ETS81689.1 - 0.78 9.0 7.1 0.24 10.7 3.6 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) PP2C_C PF07830.13 ETS81689.1 - 1.1 9.8 5.6 7.9 7.0 0.1 3.8 3 1 1 4 4 4 0 Protein serine/threonine phosphatase 2C, C-terminal domain ABC1 PF03109.16 ETS81691.1 - 6.5e-34 116.6 0.0 1.2e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Rad52_Rad22 PF04098.15 ETS81694.1 - 4e-61 205.4 0.0 6.1e-61 204.8 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein RNA_pol_Rpb1_1 PF04997.12 ETS81695.1 - 6.7e-82 275.3 0.7 1e-81 274.7 0.7 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 ETS81695.1 - 2.1e-77 260.2 0.1 3.5e-77 259.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 ETS81695.1 - 3.4e-72 242.1 0.0 7.9e-72 240.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 ETS81695.1 - 3.4e-39 134.3 0.0 8e-39 133.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 ETS81695.1 - 1e-27 96.2 0.0 3.8e-27 94.3 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF92 PF01940.16 ETS81696.1 - 1.6e-87 292.9 3.8 2e-87 292.5 3.8 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Glyco_hydro_43 PF04616.14 ETS81697.1 - 6.5e-30 104.4 10.7 1.2e-29 103.5 10.7 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ETS81697.1 - 4.1e-18 65.8 0.0 6.3e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain GATA PF00320.27 ETS81698.1 - 2.6e-12 46.1 1.5 7.4e-12 44.7 1.5 1.8 1 0 0 1 1 1 1 GATA zinc finger Auto_anti-p27 PF06677.12 ETS81698.1 - 0.13 12.4 3.1 0.092 12.9 0.6 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C2H2_4 PF13894.6 ETS81698.1 - 0.13 13.1 1.3 46 5.2 0.1 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger DZR PF12773.7 ETS81698.1 - 1.1 9.3 8.9 13 5.9 1.6 3.9 4 1 1 5 5 5 0 Double zinc ribbon Helo_like_N PF17111.5 ETS81699.1 - 0.00043 19.7 1.1 0.011 15.1 0.0 2.8 1 1 2 3 3 3 1 Fungal N-terminal domain of STAND proteins Vps51 PF08700.11 ETS81699.1 - 0.0082 16.2 0.7 0.089 12.9 0.1 3.0 3 0 0 3 3 3 1 Vps51/Vps67 HeLo PF14479.6 ETS81699.1 - 0.091 12.6 2.4 0.24 11.2 2.4 1.7 1 1 0 1 1 1 0 Prion-inhibition and propagation CorA PF01544.18 ETS81699.1 - 0.14 11.5 5.9 0.11 11.8 3.9 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein K-box PF01486.17 ETS81699.1 - 0.47 10.7 4.4 1.8 8.8 1.4 3.1 2 1 0 2 2 2 0 K-box region SHE3 PF17078.5 ETS81699.1 - 0.51 10.0 5.5 1 9.0 1.3 2.5 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 PNP_UDP_1 PF01048.20 ETS81700.1 - 2.5e-08 33.5 0.0 4.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily MFS_1 PF07690.16 ETS81701.1 - 4e-27 95.1 23.7 4e-27 95.1 23.7 1.4 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2304 PF10066.9 ETS81701.1 - 0.12 12.6 1.4 0.6 10.3 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) 2-Hacid_dh_C PF02826.19 ETS81702.1 - 1.5e-49 167.7 0.3 2.3e-49 167.1 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS81702.1 - 5.7e-07 29.3 0.0 1e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ETS81702.1 - 2e-05 24.8 0.1 3.1e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase HTH_1 PF00126.27 ETS81702.1 - 0.023 14.7 0.1 0.048 13.6 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family DUF1871 PF08958.10 ETS81702.1 - 0.15 12.4 0.0 8.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1871) FMN_dh PF01070.18 ETS81703.1 - 5.3e-112 374.3 0.0 6.4e-112 374.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ETS81703.1 - 4.9e-20 71.5 0.0 9.9e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 ETS81703.1 - 0.00013 21.3 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 ETS81703.1 - 0.0029 16.7 0.1 0.0078 15.2 0.0 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 ETS81703.1 - 0.061 12.6 0.4 1.1 8.5 0.0 2.2 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG Aldo_ket_red PF00248.21 ETS81704.1 - 1e-67 228.4 0.0 1.3e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TRI9 PF08195.11 ETS81704.1 - 0.069 13.0 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 TRI9 protein Zn_clus PF00172.18 ETS81705.1 - 7.3e-06 26.0 8.7 1.2e-05 25.4 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 ETS81706.1 - 1.3e-94 317.6 20.7 1.5e-94 317.4 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS81706.1 - 1.3e-18 67.0 60.1 3.1e-16 59.3 29.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BNR_2 PF13088.6 ETS81707.1 - 7.3e-61 205.9 0.2 9.4e-61 205.5 0.2 1.0 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 ETS81707.1 - 4.6e-05 22.8 4.9 0.065 13.3 0.1 4.3 4 0 0 4 4 4 2 BNR/Asp-box repeat BNR_3 PF13859.6 ETS81707.1 - 0.024 13.9 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 BNR repeat-like domain Sortilin-Vps10 PF15902.5 ETS81707.1 - 0.053 12.3 0.2 0.68 8.7 0.0 2.3 2 1 2 4 4 4 0 Sortilin, neurotensin receptor 3, DHDPS PF00701.22 ETS81708.1 - 4.4e-43 147.0 0.0 5.7e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family HET PF06985.11 ETS81709.1 - 4.4e-27 95.2 0.1 1.7e-26 93.3 0.0 2.1 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ETS81710.1 - 3.4e-25 89.1 0.2 6.9e-25 88.1 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box PF00646.33 ETS81711.1 - 0.00042 20.1 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ETS81711.1 - 0.0014 18.5 0.1 0.0042 17.0 0.1 1.9 2 0 0 2 2 2 1 F-box-like Ldh_2 PF02615.14 ETS81712.1 - 4e-123 410.8 2.1 4.6e-123 410.6 2.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Fungal_trans PF04082.18 ETS81713.1 - 1.2e-27 96.6 1.5 2.6e-27 95.5 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS81713.1 - 0.0081 16.3 3.3 0.016 15.3 3.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 ETS81713.1 - 0.034 14.3 0.0 0.072 13.3 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain Sugar_tr PF00083.24 ETS81714.1 - 3e-72 243.9 25.8 4.1e-72 243.5 25.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS81714.1 - 5.3e-24 84.8 27.8 5.3e-24 84.8 27.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS81714.1 - 0.00073 18.1 4.0 0.00073 18.1 4.0 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ILVD_EDD PF00920.21 ETS81715.1 - 1.3e-160 535.5 0.8 1.4e-160 535.3 0.8 1.0 1 0 0 1 1 1 1 Dehydratase family RVT_thumb PF06817.14 ETS81716.1 - 0.029 14.2 0.1 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Reverse transcriptase thumb domain FA_desaturase PF00487.24 ETS81717.1 - 1.6e-27 97.0 12.7 1.6e-27 97.0 12.7 1.6 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 ETS81717.1 - 4.4e-18 64.5 0.2 7.9e-18 63.7 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.26 ETS81718.1 - 1.9e-26 92.0 0.2 3.7e-26 91.1 0.2 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 ETS81718.1 - 0.0059 16.8 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF4407 PF14362.6 ETS81718.1 - 0.024 14.0 0.7 0.031 13.6 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 ETS81718.1 - 0.031 13.2 2.0 0.064 12.1 1.8 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein DotU PF09850.9 ETS81718.1 - 0.058 13.1 0.1 0.088 12.5 0.1 1.3 1 0 0 1 1 1 0 Type VI secretion system protein DotU DUF883 PF05957.13 ETS81718.1 - 0.089 13.4 1.8 0.14 12.8 1.3 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) FixG_C PF11614.8 ETS81718.1 - 0.089 13.0 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase APG6_N PF17675.1 ETS81718.1 - 0.11 13.1 2.2 0.18 12.3 2.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF724 PF05266.14 ETS81718.1 - 0.13 12.1 1.1 0.23 11.3 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DivIC PF04977.15 ETS81718.1 - 0.14 11.9 1.0 0.26 11.1 1.0 1.5 1 0 0 1 1 1 0 Septum formation initiator PRKG1_interact PF15898.5 ETS81718.1 - 0.23 12.4 2.6 0.45 11.4 2.6 1.4 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain SlyX PF04102.12 ETS81718.1 - 0.94 10.1 3.9 2.4 8.8 3.9 1.7 1 0 0 1 1 1 0 SlyX UBA PF00627.31 ETS81719.1 - 3.9e-06 26.6 0.0 1.1e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain UBX PF00789.20 ETS81719.1 - 0.00011 22.4 0.0 0.00029 21.0 0.0 1.8 1 0 0 1 1 1 1 UBX domain CDC45 PF02724.14 ETS81719.1 - 0.038 12.3 13.4 0.048 12.0 13.4 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2 PF00096.26 ETS81719.1 - 0.08 13.4 0.1 0.15 12.6 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF572 PF04502.13 ETS81719.1 - 0.085 12.5 19.7 0.12 11.9 19.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4776 PF16003.5 ETS81719.1 - 2.4 7.1 17.0 3.2 6.7 17.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) DUF4551 PF15087.6 ETS81719.1 - 4.3 6.0 11.4 5.4 5.7 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Mrr_N PF14338.6 ETS81719.1 - 7.5 6.8 10.9 0.53 10.5 1.7 2.9 2 1 1 3 3 3 0 Mrr N-terminal domain MCM3AP_GANP PF16769.5 ETS81719.1 - 8.9 4.4 15.2 12 4.0 15.2 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP Ribosomal_60s PF00428.19 ETS81720.1 - 1.1e-26 93.3 11.2 1.3e-26 93.0 11.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2967 PF11179.8 ETS81720.1 - 1.8 6.5 3.7 2.1 6.3 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF3824 PF12868.7 ETS81720.1 - 7 7.3 6.3 9.5 6.9 6.3 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF2408 PF10303.9 ETS81721.1 - 2.6e-40 138.1 7.1 1.4e-26 93.6 0.1 4.9 2 2 2 4 4 4 3 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.6 ETS81721.1 - 0.0044 17.4 1.5 0.0044 17.4 1.5 3.4 5 1 0 5 5 5 1 Snapin/Pallidin Exonuc_VII_L PF02601.15 ETS81721.1 - 0.034 13.7 0.9 0.058 13.0 0.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit FRB_dom PF08771.11 ETS81721.1 - 0.064 13.7 0.2 0.77 10.2 0.1 2.5 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain zf-Tim10_DDP PF02953.15 ETS81721.1 - 0.075 12.7 0.1 8.2 6.2 0.0 2.9 3 0 0 3 3 3 0 Tim10/DDP family zinc finger HlyD_2 PF12700.7 ETS81721.1 - 0.078 11.7 1.0 0.13 11.0 1.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF2115 PF09888.9 ETS81721.1 - 0.12 12.9 3.1 0.14 12.6 1.7 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) DUF1664 PF07889.12 ETS81721.1 - 0.53 10.3 4.9 0.42 10.7 1.5 2.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 ETS81721.1 - 0.74 10.0 6.5 0.29 11.3 1.8 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Ribosomal_S15 PF00312.22 ETS81721.1 - 2.1 8.6 7.2 3 8.1 0.7 3.4 2 1 1 3 3 3 0 Ribosomal protein S15 Spectrin PF00435.21 ETS81721.1 - 3.1 8.3 7.9 0.36 11.3 1.2 2.9 3 1 0 3 3 3 0 Spectrin repeat XhlA PF10779.9 ETS81721.1 - 3.7 7.8 8.9 0.63 10.3 0.2 3.7 4 1 1 5 5 5 0 Haemolysin XhlA DUF4201 PF13870.6 ETS81721.1 - 8.1 6.1 13.1 0.28 10.9 3.3 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4201) YCII PF03795.14 ETS81722.1 - 4.8e-10 39.7 0.0 6.1e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain adh_short PF00106.25 ETS81723.1 - 4.4e-24 85.0 0.0 6.6e-17 61.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS81723.1 - 1.1e-08 34.9 0.0 3e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS81723.1 - 3.1e-05 24.0 0.0 4.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ETS81724.1 - 3.7e-60 203.4 2.9 5e-60 203.0 2.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS81724.1 - 4.9e-49 166.4 4.2 5.7e-49 166.2 4.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS81724.1 - 2.9e-15 56.6 2.1 4.2e-15 56.1 2.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS81724.1 - 0.0041 16.6 1.8 0.015 14.8 1.8 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Amidohydro_3 PF07969.11 ETS81724.1 - 0.028 13.9 0.1 0.029 13.9 0.1 1.1 1 0 0 1 1 1 0 Amidohydrolase family BT1 PF03092.16 ETS81724.1 - 0.032 12.5 0.0 0.046 12.0 0.0 1.1 1 0 0 1 1 1 0 BT1 family ADH_zinc_N PF00107.26 ETS81724.1 - 0.063 13.3 1.4 1.1 9.2 0.4 2.5 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 ETS81724.1 - 0.11 13.1 0.8 1.2 9.9 0.8 2.5 1 1 0 1 1 1 0 Methyltransferase domain THF_DHG_CYH_C PF02882.19 ETS81724.1 - 0.15 11.4 0.8 0.34 10.2 0.5 1.9 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain p450 PF00067.22 ETS81725.1 - 1.7e-33 116.1 0.0 1.4e-31 109.7 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 HET PF06985.11 ETS81726.1 - 7e-22 78.4 0.0 1.4e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3433 PF11915.8 ETS81727.1 - 1.6e-25 89.4 15.1 1.8e-16 60.4 1.7 3.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) RPOL_N PF14700.6 ETS81727.1 - 0.088 12.2 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Ferric_reduct PF01794.19 ETS81728.1 - 2.2e-16 60.1 22.7 3e-16 59.7 19.3 2.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ETS81728.1 - 6.1e-09 35.9 0.0 2.3e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 ETS81728.1 - 2.8e-08 34.0 0.0 4.3e-05 23.7 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 ETS81728.1 - 0.023 15.3 0.0 0.048 14.3 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain HET PF06985.11 ETS81729.1 - 3.8e-32 111.7 0.0 7.3e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 ETS81731.1 - 8.1e-11 41.7 0.0 1.2e-08 34.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS81731.1 - 0.00034 20.2 0.0 0.00053 19.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS81731.1 - 0.15 12.0 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 KR domain Ribosomal_L37ae PF01780.19 ETS81732.1 - 0.018 15.1 0.2 0.032 14.3 0.2 1.4 1 0 0 1 1 1 0 Ribosomal L37ae protein family DUF4470 PF14737.6 ETS81734.1 - 1.9e-11 44.0 0.0 4.4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 ETS81734.1 - 3.5e-09 36.6 17.7 7.5e-09 35.5 17.7 1.6 1 0 0 1 1 1 1 MYND finger TauD PF02668.16 ETS81735.1 - 4.3e-45 154.6 0.3 5.5e-45 154.3 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pectate_lyase_3 PF12708.7 ETS81736.1 - 6.7e-79 264.7 9.3 2.1e-72 243.5 3.0 3.1 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 ETS81736.1 - 0.0001 21.9 0.3 0.028 14.1 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DUF4070 PF13282.6 ETS81738.1 - 0.19 11.8 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) WSC PF01822.19 ETS81740.1 - 2.1e-65 216.9 72.1 2.3e-18 66.1 8.2 4.9 6 0 0 6 6 6 4 WSC domain Herpes_UL49_2 PF04823.12 ETS81740.1 - 0.01 15.9 1.4 1.4 9.1 0.8 2.7 2 0 0 2 2 2 0 Herpesvirus UL49 tegument protein CAF1C_H4-bd PF12265.8 ETS81740.1 - 0.016 15.5 1.3 0.18 12.1 0.1 2.7 2 1 0 2 2 2 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex Meth_synt_1 PF08267.12 ETS81740.1 - 0.018 14.5 0.0 5 6.5 0.0 2.6 3 0 0 3 3 3 0 Cobalamin-independent synthase, N-terminal domain Sporozoite_P67 PF05642.11 ETS81740.1 - 2.3 6.2 9.8 3.9 5.4 9.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen p450 PF00067.22 ETS81741.1 - 1.7e-66 224.9 0.0 2.2e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.12 ETS81742.1 - 6.3e-23 80.7 0.7 1.3e-22 79.8 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS81742.1 - 8.5e-17 61.4 0.1 1.3e-16 60.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS81742.1 - 1e-05 26.6 0.0 1.6e-05 26.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ETS81742.1 - 0.04 13.2 0.4 0.06 12.6 0.4 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_2 PF16884.5 ETS81742.1 - 0.061 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase H_lectin PF09458.10 ETS81742.1 - 0.2 11.9 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 H-type lectin domain adh_short PF00106.25 ETS81742.1 - 0.27 10.7 0.9 0.74 9.2 0.8 1.8 1 1 0 1 1 1 0 short chain dehydrogenase DUF3425 PF11905.8 ETS81743.1 - 5.3e-07 29.6 2.0 9.5e-07 28.8 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) FlgD PF03963.14 ETS81743.1 - 0.012 15.9 0.3 0.025 14.9 0.3 1.5 1 0 0 1 1 1 0 Flagellar hook capping protein - N-terminal region bZIP_1 PF00170.21 ETS81743.1 - 5.4 7.2 9.8 0.54 10.4 5.2 1.8 2 0 0 2 2 2 0 bZIP transcription factor HET PF06985.11 ETS81746.1 - 1.2e-11 45.2 7.1 2.2e-10 41.1 4.1 3.8 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF4245 PF14030.6 ETS81746.1 - 0.08 12.9 0.3 0.92 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) p450 PF00067.22 ETS81747.1 - 8.2e-70 235.8 0.0 9.8e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EHN PF06441.12 ETS81748.1 - 5.4e-34 116.8 1.6 6.6e-33 113.3 0.1 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ETS81748.1 - 3.7e-07 30.0 0.0 7.7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS81748.1 - 0.0012 19.5 4.4 0.0023 18.6 4.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_2 PF00891.18 ETS81750.1 - 4.4e-18 65.4 0.0 6e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_11 PF08241.12 ETS81752.1 - 2.1e-14 53.9 0.1 4.4e-14 52.9 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS81752.1 - 4.6e-14 52.9 0.0 8.1e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS81752.1 - 9.6e-12 44.9 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS81752.1 - 4.6e-09 36.3 0.0 5.7e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS81752.1 - 7.3e-08 33.1 0.2 1.4e-06 28.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 ETS81752.1 - 0.00011 21.7 0.7 0.00014 21.3 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 ETS81752.1 - 0.00016 21.1 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ETS81752.1 - 0.00025 20.6 0.0 0.00042 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 ETS81752.1 - 0.042 13.4 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_16 PF10294.9 ETS81752.1 - 0.051 13.3 0.1 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Lysine methyltransferase ADH_zinc_N PF00107.26 ETS81752.1 - 0.093 12.7 0.1 0.4 10.7 0.1 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_32 PF13679.6 ETS81752.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 ETS81753.1 - 2.8e-38 131.7 54.1 7.9e-29 100.7 31.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS81753.1 - 2.3e-11 43.2 22.3 1.1e-07 31.1 7.5 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter CytB6-F_Fe-S PF08802.10 ETS81753.1 - 7.6 6.7 6.8 1.9 8.6 1.5 2.7 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit DIOX_N PF14226.6 ETS81754.1 - 5.3e-19 69.1 0.2 7.7e-19 68.6 0.2 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS81754.1 - 1.4e-12 48.0 0.0 2.3e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HET PF06985.11 ETS81755.1 - 2.1e-13 50.9 5.4 5e-11 43.1 1.4 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PspA_IM30 PF04012.12 ETS81756.1 - 0.015 14.9 0.4 0.022 14.3 0.4 1.2 1 0 0 1 1 1 0 PspA/IM30 family DUF4839 PF16127.5 ETS81756.1 - 0.14 12.2 0.0 0.4 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4839) His_Phos_1 PF00300.22 ETS81757.1 - 2.9e-12 46.7 0.7 6.9e-12 45.5 0.1 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) WI12 PF07107.11 ETS81757.1 - 0.045 13.9 0.0 0.081 13.1 0.0 1.4 1 0 0 1 1 1 0 Wound-induced protein WI12 zf-RING_11 PF17123.5 ETS81758.1 - 2.6e-05 23.9 4.0 0.00018 21.2 0.2 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 ETS81758.1 - 5.7e-05 23.0 2.4 0.00015 21.6 2.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 ETS81758.1 - 0.0001 22.5 2.1 0.0001 22.5 2.1 2.2 1 1 1 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 ETS81758.1 - 0.00034 20.8 0.5 0.00094 19.4 0.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ETS81758.1 - 0.0014 18.4 2.5 0.0014 18.4 2.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ETS81758.1 - 0.0015 18.4 1.6 0.0015 18.4 1.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS81758.1 - 0.002 18.1 0.9 0.002 18.1 0.9 2.4 1 1 1 2 2 2 1 RING-type zinc-finger DUF4054 PF13262.6 ETS81758.1 - 0.034 14.2 0.3 0.072 13.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) Prok-RING_4 PF14447.6 ETS81758.1 - 0.036 13.9 6.0 0.088 12.7 6.0 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 ETS81758.1 - 0.046 13.4 0.3 0.046 13.4 0.3 2.6 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type Mito_carr PF00153.27 ETS81759.1 - 1.9e-64 213.6 1.5 9.3e-22 76.8 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.16 ETS81760.1 - 2e-44 149.6 1.0 2.4e-44 149.4 1.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit SMC_hinge PF06470.13 ETS81760.1 - 0.049 13.9 0.0 0.071 13.4 0.0 1.2 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain Anp1 PF03452.14 ETS81761.1 - 4.6e-108 360.6 0.0 5.7e-108 360.3 0.0 1.1 1 0 0 1 1 1 1 Anp1 DUF3328 PF11807.8 ETS81761.1 - 0.02 14.7 0.1 0.04 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) HhH-GPD PF00730.25 ETS81762.1 - 2.1e-15 57.1 0.0 6.2e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HTH_Tnp_Tc3_2 PF01498.18 ETS81762.1 - 0.049 13.9 0.1 1.3 9.3 0.1 2.5 2 0 0 2 2 2 0 Transposase Ndc1_Nup PF09531.10 ETS81762.1 - 0.32 9.6 1.2 0.32 9.6 1.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Recep_L_domain PF01030.24 ETS81763.1 - 1.3e-06 28.4 0.4 0.55 10.4 0.0 4.8 1 1 3 4 4 4 2 Receptor L domain Ecm33 PF12454.8 ETS81763.1 - 0.0086 16.2 0.2 0.031 14.4 0.2 2.0 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein SLAIN PF15301.6 ETS81763.1 - 0.02 14.2 0.3 0.02 14.2 0.3 1.7 2 0 0 2 2 2 0 SLAIN motif-containing family Lysis_col PF02402.16 ETS81763.1 - 6.3 6.6 7.1 1.8 8.3 0.1 2.6 2 0 0 2 2 2 0 Lysis protein G-patch PF01585.23 ETS81764.1 - 5e-12 45.5 2.5 1.5e-11 44.0 2.5 1.9 1 0 0 1 1 1 1 G-patch domain UPF0449 PF15136.6 ETS81764.1 - 0.015 15.8 0.2 0.015 15.8 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 RRM_1 PF00076.22 ETS81764.1 - 0.028 14.2 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ETS81764.1 - 0.029 14.4 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif AMP-binding PF00501.28 ETS81765.1 - 1.8e-88 297.0 0.0 2.1e-88 296.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS81765.1 - 2.8e-16 60.2 0.4 7.2e-16 58.9 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 ETS81765.1 - 0.00025 20.1 0.0 0.0012 17.8 0.0 1.9 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 ETS81765.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 RTX C-terminal domain DUF737 PF05300.11 ETS81766.1 - 0.076 13.4 1.8 0.091 13.1 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Dynamin_N PF00350.23 ETS81767.1 - 8.7e-32 110.5 0.1 8.7e-32 110.5 0.1 1.7 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 ETS81767.1 - 5.9e-24 84.8 0.3 2.4e-22 79.5 0.0 2.9 2 1 1 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.23 ETS81767.1 - 1e-06 28.8 0.3 1.9e-05 24.7 0.3 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 ETS81767.1 - 0.0022 18.1 2.3 0.0022 18.1 2.3 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain Corazonin PF17308.2 ETS81767.1 - 0.0032 17.8 0.8 0.18 12.2 0.0 2.6 2 0 0 2 2 2 1 Pro-corazonin FeoB_N PF02421.18 ETS81767.1 - 0.011 15.3 0.0 0.67 9.5 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.6 ETS81767.1 - 0.026 14.4 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF952 PF06108.12 ETS81767.1 - 0.03 14.3 0.1 0.093 12.7 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF952) AAA_29 PF13555.6 ETS81767.1 - 0.034 13.9 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 ETS81767.1 - 0.039 14.5 0.3 0.43 11.1 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_15 PF13175.6 ETS81767.1 - 0.058 13.1 0.2 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 ETS81767.1 - 0.059 13.6 0.0 0.84 9.9 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF5101 PF17031.5 ETS81767.1 - 0.68 10.1 3.7 20 5.4 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5101) Cnn_1N PF07989.11 ETS81767.1 - 0.77 9.9 5.5 0.46 10.7 2.7 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 HET PF06985.11 ETS81768.1 - 3.7e-33 114.9 0.0 7.2e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.7 ETS81771.1 - 4.5e-13 50.3 4.9 6.7e-13 49.8 4.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS81771.1 - 4.3e-06 26.2 0.0 6.5e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 ETS81771.1 - 0.0084 16.0 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 ETS81771.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.20 ETS81771.1 - 0.031 13.9 0.1 0.15 11.6 0.1 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.14 ETS81771.1 - 0.055 13.0 0.0 0.079 12.5 0.0 1.3 1 1 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 ETS81771.1 - 0.057 13.1 0.0 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein CorA PF01544.18 ETS81772.1 - 4e-11 42.8 0.3 1.1e-10 41.4 0.1 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein ICE2 PF08426.10 ETS81773.1 - 9.8e-158 525.5 8.0 1.1e-157 525.3 8.0 1.0 1 0 0 1 1 1 1 ICE2 TetR_C_33 PF13305.6 ETS81774.1 - 0.058 14.2 0.4 0.21 12.4 0.1 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Fungal_trans_2 PF11951.8 ETS81774.1 - 0.088 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Hydrolase_6 PF13344.6 ETS81775.1 - 7.7e-29 99.8 0.0 3.2e-28 97.8 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ETS81775.1 - 3.1e-16 59.2 0.1 1.4e-15 57.1 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 ETS81775.1 - 2.2e-06 28.1 0.3 0.011 16.0 0.2 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ETS81775.1 - 0.00038 20.6 0.2 1.7 8.7 0.0 3.3 3 1 1 4 4 4 2 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ETS81775.1 - 0.088 12.5 0.0 0.27 10.9 0.0 1.8 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Myf5 PF12232.8 ETS81776.1 - 2.3 9.0 11.1 0.12 13.1 3.7 2.8 2 0 0 2 2 2 0 Myogenic determination factor 5 CDH-cyt PF16010.5 ETS81777.1 - 1e-67 227.4 5.1 8.7e-67 224.3 3.9 2.4 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 ETS81777.1 - 6.3e-27 94.7 0.0 1.2e-26 93.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS81777.1 - 1e-20 74.7 0.4 2.7e-20 73.3 0.4 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS81777.1 - 3.2e-08 33.1 0.1 0.00051 19.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 ETS81777.1 - 2.7e-05 23.9 0.8 0.00067 19.3 0.4 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS81777.1 - 2.7e-05 24.3 0.0 8.1e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS81777.1 - 3.6e-05 23.1 0.4 0.00037 19.8 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS81777.1 - 0.0022 16.8 0.0 0.0067 15.2 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 ETS81777.1 - 0.0097 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 ETS81777.1 - 0.011 16.3 0.0 0.62 10.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DOMON PF03351.17 ETS81777.1 - 0.013 15.7 0.0 0.039 14.2 0.0 1.8 1 0 0 1 1 1 0 DOMON domain Pyr_redox_3 PF13738.6 ETS81777.1 - 0.013 14.7 0.1 0.089 12.0 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lon_2 PF13337.6 ETS81777.1 - 0.08 11.5 0.0 0.19 10.3 0.0 1.5 2 0 0 2 2 2 0 Putative ATP-dependent Lon protease DUF3439 PF11921.8 ETS81777.1 - 5.2 7.0 14.8 12 5.9 14.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_hydro_61 PF03443.14 ETS81778.1 - 3.7e-46 157.7 0.4 4.6e-46 157.4 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SRAP PF02586.14 ETS81779.1 - 8.9e-77 257.5 0.0 1.5e-76 256.8 0.0 1.3 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Ribosomal_L18 PF17135.4 ETS81780.1 - 2.7e-93 310.6 2.8 3.1e-93 310.4 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 ETS81780.1 - 0.018 15.7 0.1 0.048 14.3 0.1 1.9 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Mito_carr PF00153.27 ETS81781.1 - 8e-75 246.9 0.4 2.2e-25 88.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ETS81781.1 - 0.0016 17.6 0.1 0.11 11.7 0.0 3.0 3 1 1 4 4 4 1 Gammaproteobacterial serine protease RRM_1 PF00076.22 ETS81782.1 - 3.8e-12 45.9 0.0 5.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ETS81782.1 - 7.4e-05 22.7 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif C2 PF00168.30 ETS81783.1 - 5.7e-17 61.9 0.0 1e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain Abhydrolase_4 PF08386.10 ETS81784.1 - 1.1e-21 76.8 0.0 2.3e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 ETS81784.1 - 7.4e-18 65.1 0.0 1.3e-12 48.0 0.0 3.0 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS81784.1 - 0.018 14.3 0.3 22 4.2 0.0 3.3 3 0 0 3 3 3 0 Serine aminopeptidase, S33 HGD-D PF06050.13 ETS81784.1 - 0.044 13.5 0.0 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component Fungal_TACC PF12709.7 ETS81785.1 - 3.8e-09 36.8 5.6 3.8e-09 36.8 5.6 4.8 3 1 1 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins DUF2570 PF10828.8 ETS81785.1 - 0.011 15.6 2.4 0.011 15.6 2.4 3.7 3 1 0 4 4 4 0 Protein of unknown function (DUF2570) HIP1_clath_bdg PF16515.5 ETS81785.1 - 0.015 15.9 3.4 0.015 15.9 3.4 5.4 4 1 1 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3584 PF12128.8 ETS81785.1 - 0.1 10.1 33.2 0.019 12.6 11.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF4201 PF13870.6 ETS81785.1 - 0.36 10.5 26.0 0.077 12.7 7.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) PspA_IM30 PF04012.12 ETS81785.1 - 0.62 9.6 43.8 0.11 12.1 18.5 3.5 1 1 2 3 3 3 0 PspA/IM30 family DUF4407 PF14362.6 ETS81785.1 - 0.83 9.0 27.0 1.6 8.0 10.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 ETS81785.1 - 1.6 8.6 33.7 0.53 10.1 8.6 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 ETS81785.1 - 3.1 7.0 27.7 4.2 6.6 9.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) MCC-bdg_PDZ PF10506.9 ETS81785.1 - 7 6.7 8.4 4.5 7.4 0.6 3.7 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome zf-CCHC PF00098.23 ETS81786.1 - 0.0082 16.2 1.5 0.0082 16.2 1.5 2.3 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_4 PF14392.6 ETS81786.1 - 0.14 11.9 0.4 0.33 10.7 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 ETS81786.1 - 0.77 9.5 4.2 10 5.9 0.2 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 ETS81786.1 - 4.2 7.3 6.1 0.83 9.5 1.9 2.0 2 0 0 2 2 2 0 Zinc knuckle Glyco_hydro_28 PF00295.17 ETS81787.1 - 1.4e-103 346.4 20.7 2.2e-103 345.7 20.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Syntaxin PF00804.25 ETS81788.1 - 5.5e-19 68.6 12.0 5.5e-19 68.6 12.0 2.1 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 ETS81788.1 - 4.7e-13 48.9 0.5 4.7e-13 48.9 0.5 2.7 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 ETS81788.1 - 8.7e-05 22.8 13.4 0.00032 21.0 4.2 2.5 2 0 0 2 2 2 1 Syntaxin-like protein UL42 PF17638.2 ETS81788.1 - 0.0047 16.9 0.6 0.0095 15.9 0.6 1.4 1 0 0 1 1 1 1 HCMV UL42 Orf78 PF06024.12 ETS81788.1 - 0.0087 16.4 1.1 0.0087 16.4 1.1 2.2 2 0 0 2 2 2 1 Orf78 (ac78) Ferritin PF00210.24 ETS81788.1 - 0.013 15.4 3.0 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 Ferritin-like domain LMBR1 PF04791.16 ETS81788.1 - 0.017 14.1 5.0 0.024 13.6 5.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Synaptobrevin PF00957.21 ETS81788.1 - 0.017 14.9 4.9 0.063 13.1 4.9 2.0 1 0 0 1 1 1 0 Synaptobrevin EphA2_TM PF14575.6 ETS81788.1 - 0.036 14.9 0.1 0.036 14.9 0.1 2.2 2 1 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 ETS81788.1 - 0.055 13.5 5.3 0.11 12.6 5.3 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Ac76 PF05814.11 ETS81788.1 - 0.061 13.3 0.2 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 Orf76 (Ac76) TMEM154 PF15102.6 ETS81788.1 - 0.063 13.2 0.5 0.16 11.9 0.5 1.7 1 0 0 1 1 1 0 TMEM154 protein family GRIM-19 PF06212.12 ETS81788.1 - 0.07 13.1 1.0 0.26 11.2 0.1 2.1 2 0 0 2 2 2 0 GRIM-19 protein Baculo_11_kDa PF06143.11 ETS81788.1 - 0.077 12.6 1.3 0.32 10.6 1.3 2.0 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF2207 PF09972.9 ETS81788.1 - 0.09 11.5 3.2 0.084 11.6 0.5 1.8 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) NB PF04159.13 ETS81788.1 - 0.093 12.8 1.3 0.17 12.0 1.3 1.4 1 0 0 1 1 1 0 NB glycoprotein Picorna_P3A PF06363.11 ETS81788.1 - 0.099 12.5 0.2 0.2 11.5 0.2 1.5 1 0 0 1 1 1 0 Picornaviridae P3A protein ETRAMP PF09716.10 ETS81788.1 - 0.13 12.3 1.7 0.44 10.6 1.7 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) KNOX2 PF03791.13 ETS81788.1 - 0.23 11.0 1.4 30 4.2 0.1 3.4 3 0 0 3 3 3 0 KNOX2 domain Tweety PF04906.13 ETS81788.1 - 0.25 10.0 8.0 0.23 10.1 3.7 2.0 2 0 0 2 2 2 0 Tweety Mod_r PF07200.13 ETS81788.1 - 0.3 11.2 18.8 1.2 9.3 5.8 2.8 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4407 PF14362.6 ETS81788.1 - 0.72 9.1 17.0 44 3.3 17.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4179 PF13786.6 ETS81788.1 - 0.77 10.3 3.5 7.8 7.0 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) ODV-E18 PF10717.9 ETS81788.1 - 0.87 9.5 3.7 0.31 10.9 0.6 1.8 2 0 0 2 2 1 0 Occlusion-derived virus envelope protein ODV-E18 BLOC1_2 PF10046.9 ETS81788.1 - 1.4 9.2 9.4 1.5 9.1 3.3 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ASFV_J13L PF05568.11 ETS81788.1 - 2.5 7.8 6.7 0.49 10.1 2.2 1.9 2 0 0 2 2 2 0 African swine fever virus J13L protein TMPIT PF07851.13 ETS81788.1 - 2.8 7.1 11.6 2.4 7.3 3.1 2.3 2 0 0 2 2 2 0 TMPIT-like protein SKA1 PF07160.12 ETS81788.1 - 3.6 7.4 14.5 0.22 11.4 3.7 2.6 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF2721 PF11026.8 ETS81788.1 - 4.2 7.3 7.0 11 5.9 0.3 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF2721) TssO PF17561.2 ETS81788.1 - 4.2 7.5 13.7 2.9 8.0 1.3 3.4 3 1 0 3 3 3 0 Type VI secretion system, TssO V-SNARE PF05008.15 ETS81788.1 - 4.8 7.6 17.6 0.41 11.1 3.4 4.0 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus RIFIN PF02009.16 ETS81788.1 - 5.6 6.8 13.6 25 4.7 13.6 1.9 1 1 0 1 1 1 0 Rifin zf-CpG_bind_C PF12269.8 ETS81788.1 - 6.6 6.4 10.1 8.6 6.1 2.1 2.2 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain HisKA_3 PF07730.13 ETS81788.1 - 8.4 7.0 11.0 6.4 7.4 1.0 3.7 2 2 2 4 4 3 0 Histidine kinase DUF4051 PF13260.6 ETS81788.1 - 9.9 6.0 6.4 1.6 8.5 0.4 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF4051) RCR PF12273.8 ETS81789.1 - 7.1e-12 46.0 12.4 1.2e-11 45.2 12.4 1.5 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red PspB PF06667.12 ETS81789.1 - 0.035 14.2 0.3 0.048 13.7 0.3 1.2 1 0 0 1 1 1 0 Phage shock protein B DUF680 PF05079.12 ETS81790.1 - 0.32 11.7 4.5 0.36 11.6 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF680) tRNA-synt_2c PF01411.19 ETS81791.1 - 6.7e-217 721.4 0.1 6.7e-217 721.4 0.1 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 ETS81791.1 - 3.6e-16 59.0 0.4 8.3e-16 57.8 0.4 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 ETS81791.1 - 5.6e-07 30.1 2.5 5.6e-07 30.1 2.5 2.2 2 0 0 2 2 2 1 DHHA1 domain DUF1902 PF08972.11 ETS81791.1 - 0.098 12.7 0.1 0.32 11.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) 5-FTHF_cyc-lig PF01812.20 ETS81792.1 - 3.9e-08 33.4 0.0 5.3e-08 32.9 0.0 1.3 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family C6_DPF PF10170.9 ETS81793.1 - 0.81 10.1 4.3 3.9 7.9 3.0 2.2 2 0 0 2 2 2 0 Cysteine-rich domain FYVE_2 PF02318.16 ETS81793.1 - 1.1 9.5 4.4 0.36 11.0 1.1 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger IBR PF01485.21 ETS81793.1 - 5.2 7.4 9.5 11 6.4 7.9 2.3 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Siva PF05458.12 ETS81793.1 - 6 6.5 11.1 81 2.8 11.1 2.7 1 1 0 1 1 1 0 Cd27 binding protein (Siva) DnaJ-X PF14308.6 ETS81794.1 - 6.2e-78 261.0 1.7 6.2e-78 261.0 1.7 2.1 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 ETS81794.1 - 1.5e-25 89.1 1.1 3.9e-25 87.7 1.1 1.8 1 0 0 1 1 1 1 DnaJ domain AAR2 PF05282.11 ETS81794.1 - 0.062 12.7 3.6 1.4 8.2 0.2 2.3 2 0 0 2 2 2 0 AAR2 protein DUF2924 PF11149.8 ETS81794.1 - 0.65 10.4 3.3 14 6.1 0.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) RmlD_sub_bind PF04321.17 ETS81795.1 - 5.7e-18 65.0 0.0 2.5e-17 62.9 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 ETS81795.1 - 3.8e-15 56.0 0.0 5.9e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS81795.1 - 1.9e-05 24.3 0.0 7.2e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ETS81795.1 - 9.8e-05 21.6 0.0 0.00016 20.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ETS81795.1 - 0.00053 19.1 0.1 0.0023 17.0 0.1 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ETS81795.1 - 0.02 14.1 0.1 0.13 11.4 0.0 2.0 1 1 1 2 2 2 0 Male sterility protein C2-set_2 PF08205.12 ETS81795.1 - 0.035 14.2 0.1 0.067 13.3 0.1 1.5 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain adh_short PF00106.25 ETS81795.1 - 0.12 11.8 0.1 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.10 ETS81795.1 - 0.16 11.9 0.2 2.3 8.1 0.2 2.1 1 1 1 2 2 2 0 KR domain SQS_PSY PF00494.19 ETS81796.1 - 7.2e-38 130.6 0.0 1.5e-37 129.6 0.0 1.5 2 0 0 2 2 2 1 Squalene/phytoene synthase Glyco_hydro_42 PF02449.15 ETS81796.1 - 0.038 13.3 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase Peptidase_S8 PF00082.22 ETS81797.1 - 4.1e-28 98.5 17.8 7.1e-28 97.7 17.6 1.5 1 1 0 1 1 1 1 Subtilase family CNH PF00780.22 ETS81797.1 - 0.03 13.9 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 CNH domain VCX_VCY PF15231.6 ETS81798.1 - 0.025 15.3 1.3 0.044 14.5 1.3 1.3 1 0 0 1 1 1 0 Variable charge X/Y family F-box-like PF12937.7 ETS81798.1 - 0.025 14.4 0.0 0.092 12.7 0.0 2.0 2 1 0 2 2 2 0 F-box-like Mannosyl_trans PF05007.13 ETS81799.1 - 1.3e-77 261.2 9.6 2e-77 260.6 9.6 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 ETS81799.1 - 4.7e-11 42.4 4.2 4.7e-11 42.4 4.2 2.4 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U Translin PF01997.16 ETS81800.1 - 4.2e-59 200.0 0.0 5.5e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Translin family MmlI PF09448.10 ETS81800.1 - 0.069 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase DUF3450 PF11932.8 ETS81800.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Pkinase PF00069.25 ETS81801.1 - 1.2e-28 100.2 0.0 7.2e-16 58.3 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS81801.1 - 1.4e-15 57.3 0.0 9e-09 35.0 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 ETS81801.1 - 0.0001 21.7 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ETS81801.1 - 0.02 14.5 0.4 0.041 13.5 0.1 1.7 2 0 0 2 2 2 0 RIO1 family ABC_tran PF00005.27 ETS81802.1 - 7e-47 159.4 0.1 1.3e-28 100.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS81802.1 - 3.5e-36 125.3 31.4 1.3e-27 97.2 9.5 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ETS81802.1 - 5.5e-12 45.6 0.9 4.3e-05 23.1 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETS81802.1 - 7.2e-11 42.4 1.2 0.0011 18.9 0.0 3.8 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ETS81802.1 - 4.3e-08 32.8 0.2 0.0036 17.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ETS81802.1 - 1.9e-05 25.1 0.7 0.22 11.9 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 ETS81802.1 - 4.4e-05 23.7 0.0 0.24 11.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 ETS81802.1 - 4.5e-05 23.6 0.3 0.027 14.5 0.1 2.7 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 ETS81802.1 - 8.1e-05 22.7 0.0 0.19 11.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 ETS81802.1 - 0.00011 22.8 5.1 0.078 13.5 0.1 2.7 3 0 0 3 3 2 2 AAA domain T2SSE PF00437.20 ETS81802.1 - 0.00014 21.0 0.3 0.14 11.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 ETS81802.1 - 0.00031 21.0 3.5 0.12 12.6 0.6 3.3 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ETS81802.1 - 0.00042 20.3 0.2 1 9.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FtsK_SpoIIIE PF01580.18 ETS81802.1 - 0.00048 19.5 0.4 0.057 12.8 0.0 2.9 3 0 0 3 3 3 1 FtsK/SpoIIIE family DUF87 PF01935.17 ETS81802.1 - 0.00063 19.9 1.0 0.0035 17.5 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_18 PF13238.6 ETS81802.1 - 0.0018 18.8 0.1 2.1 8.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 ETS81802.1 - 0.0027 17.5 0.7 2 8.0 0.2 2.4 2 0 0 2 2 2 2 AAA ATPase domain NB-ARC PF00931.22 ETS81802.1 - 0.0028 16.9 0.0 0.84 8.8 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain SbcCD_C PF13558.6 ETS81802.1 - 0.0052 17.0 0.2 4.1 7.7 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 ETS81802.1 - 0.016 15.0 0.4 1.8 8.2 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ETS81802.1 - 0.052 13.1 0.3 7.7 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain zf-ISL3 PF14690.6 ETS81802.1 - 0.06 14.0 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 GTP_EFTU PF00009.27 ETS81802.1 - 0.09 12.3 0.2 17 4.9 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 ETS81802.1 - 0.11 12.6 0.1 3.3 7.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain ABC_ATPase PF09818.9 ETS81802.1 - 0.13 11.1 1.5 1.1 8.0 0.1 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class NACHT PF05729.12 ETS81802.1 - 0.15 12.0 2.5 5.8 6.8 0.0 3.2 3 0 0 3 3 3 0 NACHT domain DEAD PF00270.29 ETS81802.1 - 0.27 11.0 1.7 0.97 9.2 0.5 2.3 2 1 0 2 2 1 0 DEAD/DEAH box helicase cobW PF02492.19 ETS81802.1 - 0.28 10.7 4.2 6.8 6.2 0.6 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 ETS81802.1 - 0.44 10.4 1.2 2.5 8.0 0.1 2.4 2 0 0 2 2 2 0 NTPase SPX PF03105.19 ETS81803.1 - 0.06 13.3 3.2 0.069 13.1 3.2 1.2 1 0 0 1 1 1 0 SPX domain E7 PF00527.18 ETS81803.1 - 0.086 13.1 1.3 6.3 7.1 1.1 2.7 1 1 1 2 2 2 0 E7 protein, Early protein DUF2321 PF10083.9 ETS81803.1 - 0.15 11.7 0.1 0.69 9.5 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Pex14_N PF04695.13 ETS81803.1 - 0.72 10.5 11.1 2.5 8.8 0.5 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FUSC_2 PF13515.6 ETS81803.1 - 2.1 8.5 7.1 3.5 7.7 7.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein-like NAD_binding_8 PF13450.6 ETS81804.1 - 3.2e-16 59.3 0.0 6.2e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS81804.1 - 7.5e-06 25.8 0.1 6.8e-05 22.6 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS81804.1 - 0.0056 16.0 0.0 0.27 10.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS81804.1 - 0.022 14.0 0.1 0.047 12.9 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 ETS81804.1 - 0.034 13.2 0.0 0.11 11.5 0.0 1.8 2 1 1 3 3 3 0 FAD binding domain NAD_binding_9 PF13454.6 ETS81804.1 - 0.05 13.6 0.1 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 ETS81804.1 - 0.055 14.0 0.0 3.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SdrD_B PF17210.3 ETS81804.1 - 0.19 12.0 0.1 0.39 11.0 0.1 1.5 1 0 0 1 1 1 0 SdrD B-like domain FA_hydroxylase PF04116.13 ETS81806.1 - 3.8e-09 37.0 10.9 3.8e-09 37.0 10.9 2.7 3 2 1 4 4 4 1 Fatty acid hydroxylase superfamily LIP PF03583.14 ETS81807.1 - 2.1e-57 194.7 0.1 2.9e-57 194.2 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Gpr1_Fun34_YaaH PF01184.19 ETS81809.1 - 5.1e-90 300.6 22.6 5.9e-90 300.4 22.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family RasGAP PF00616.19 ETS81810.1 - 5.6e-48 163.4 0.0 1.6e-47 161.9 0.0 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 ETS81810.1 - 3e-46 156.9 3.1 3e-46 156.9 3.1 2.5 3 0 0 3 3 3 1 RasGAP C-terminus IQ PF00612.27 ETS81810.1 - 1.1e-17 62.0 35.0 0.07 13.0 1.2 13.5 14 0 0 14 14 14 7 IQ calmodulin-binding motif CH PF00307.31 ETS81810.1 - 1.7e-09 37.8 0.0 8.3e-09 35.6 0.0 2.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Syntaxin-6_N PF09177.11 ETS81810.1 - 2.9 8.5 7.7 1.7 9.3 0.1 4.2 3 1 1 4 4 4 0 Syntaxin 6, N-terminal IMPDH PF00478.25 ETS81811.1 - 6.1e-124 413.5 4.9 7.3e-124 413.2 4.9 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 ETS81811.1 - 1.6e-12 47.6 0.1 1.9e-05 25.0 0.1 2.6 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 ETS81811.1 - 6.1e-08 32.4 0.4 0.0059 16.0 0.2 2.6 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 ETS81811.1 - 9.9e-07 28.1 1.6 1.6e-05 24.1 0.5 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 ETS81811.1 - 0.0032 17.0 3.7 0.083 12.3 0.2 2.5 2 1 1 3 3 3 2 Histidine biosynthesis protein PK PF00224.21 ETS81811.1 - 0.03 13.2 0.0 0.098 11.5 0.0 1.8 2 1 0 2 2 2 0 Pyruvate kinase, barrel domain YpsA PF06908.11 ETS81811.1 - 0.043 13.8 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family ThiG PF05690.14 ETS81811.1 - 0.06 12.6 0.9 0.15 11.3 0.2 1.9 2 1 1 3 3 3 0 Thiazole biosynthesis protein ThiG Cuticle_1 PF08140.11 ETS81811.1 - 0.13 12.3 0.9 15 5.8 0.3 2.8 2 0 0 2 2 2 0 Crustacean cuticle protein repeat TFR_dimer PF04253.15 ETS81812.1 - 9.3e-33 112.9 0.1 1.7e-32 112.1 0.1 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 ETS81812.1 - 1.7e-17 63.8 0.0 3.3e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ETS81812.1 - 1.1e-08 35.0 0.2 2.9e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.15 ETS81812.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Apolipoprotein PF01442.18 ETS81812.1 - 0.18 11.7 1.5 0.27 11.1 1.5 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain MFS_1 PF07690.16 ETS81813.1 - 4.5e-31 108.1 34.6 1.1e-25 90.3 5.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS81813.1 - 6.5e-09 35.2 3.5 6.5e-09 35.2 3.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 ETS81813.1 - 0.00051 19.0 6.9 0.012 14.5 0.9 2.4 2 0 0 2 2 2 2 MFS_1 like family ADH_N PF08240.12 ETS81814.1 - 2.5e-07 30.5 0.0 4.8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.8 ETS81814.1 - 0.12 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) DUF3040 PF11239.8 ETS81816.1 - 0.057 13.7 0.7 0.057 13.7 0.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3040) AC_N PF16214.5 ETS81816.1 - 1.5 7.9 6.8 0.079 12.1 0.5 1.8 2 0 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region gag-asp_proteas PF13975.6 ETS81818.1 - 0.00067 20.2 0.0 0.0014 19.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 ETS81818.1 - 0.0039 17.8 0.0 0.01 16.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Cyclin_N PF00134.23 ETS81819.1 - 1.7e-37 128.0 0.2 4.1e-37 126.8 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ETS81819.1 - 1e-11 44.9 0.1 3.4e-11 43.3 0.1 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain zf-ANAPC11 PF12861.7 ETS81821.1 - 7.4e-46 154.2 11.8 8.4e-46 154.0 11.8 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 ETS81821.1 - 1.5e-21 76.4 12.6 2.2e-21 75.9 12.6 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ETS81821.1 - 2.1e-08 34.3 16.2 4.5e-07 30.1 16.2 2.4 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ETS81821.1 - 1.4e-05 25.0 8.2 0.00079 19.4 9.5 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ETS81821.1 - 0.0004 20.2 15.4 0.0016 18.3 15.4 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS81821.1 - 0.0006 19.6 8.1 0.0006 19.6 8.1 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 ETS81821.1 - 0.0016 18.1 3.3 0.0016 18.1 3.3 2.4 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 ETS81821.1 - 0.0028 17.8 16.8 0.05 13.8 16.8 3.0 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 ETS81821.1 - 0.0033 17.0 12.2 0.029 14.0 12.2 2.1 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 ETS81821.1 - 0.0066 16.3 14.1 0.0066 16.3 14.1 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 ETS81821.1 - 0.013 15.3 5.4 0.021 14.6 5.4 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 ETS81821.1 - 0.016 15.3 12.5 0.017 15.2 9.9 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 ETS81821.1 - 0.048 13.5 3.2 0.21 11.5 0.0 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 ETS81821.1 - 0.071 12.9 11.0 0.48 10.2 8.9 2.9 2 1 0 2 2 2 0 RING-like zinc finger zf-HIT PF04438.16 ETS81821.1 - 0.091 12.6 1.0 0.091 12.6 1.0 2.3 2 0 0 2 2 2 0 HIT zinc finger YacG PF03884.14 ETS81821.1 - 0.1 12.3 5.1 0.41 10.4 0.1 2.7 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-RING_5 PF14634.6 ETS81821.1 - 0.28 11.2 18.1 11 6.1 18.6 2.8 1 1 1 2 2 2 0 zinc-RING finger domain UBZ_FAAP20 PF15750.5 ETS81821.1 - 0.51 10.3 6.1 2 8.5 0.2 2.8 2 1 1 3 3 3 0 Ubiquitin-binding zinc-finger Prok-RING_4 PF14447.6 ETS81821.1 - 1.1 9.2 15.0 6.5 6.7 11.5 2.4 1 1 2 3 3 3 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 ETS81821.1 - 1.2 9.5 13.2 2.7 8.4 11.4 2.2 1 1 1 2 2 2 0 RING-like domain RINGv PF12906.7 ETS81821.1 - 1.5 9.0 14.1 2.7 8.2 12.9 2.1 1 1 1 2 2 2 0 RING-variant domain zf-HC5HC2H_2 PF13832.6 ETS81821.1 - 2.4 8.3 11.6 1.5 9.0 6.1 2.2 1 1 1 2 2 2 0 PHD-zinc-finger like domain Opy2 PF09463.10 ETS81821.1 - 3.1 8.2 11.8 7.8 6.9 6.4 2.4 2 1 0 2 2 2 0 Opy2 protein DZR PF12773.7 ETS81821.1 - 5.6 7.1 13.0 4.4 7.4 5.8 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-C2H2_9 PF16293.5 ETS81821.1 - 10 6.1 8.0 13 5.7 0.0 3.4 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) Rhodanese PF00581.20 ETS81822.1 - 3e-20 72.7 0.0 7.8e-12 45.7 0.0 2.4 2 1 0 2 2 2 2 Rhodanese-like domain TilS_C PF11734.8 ETS81822.1 - 0.14 11.6 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 TilS substrate C-terminal domain Ribosomal_S5 PF00333.20 ETS81823.1 - 1.5e-27 95.4 0.9 3.5e-27 94.2 0.9 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 ETS81823.1 - 4.4e-23 80.5 0.0 7.1e-23 79.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 ETS81823.1 - 4.2 8.0 15.4 9.5 6.9 15.4 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 WSC PF01822.19 ETS81824.1 - 8.7e-16 57.9 6.2 1.9e-15 56.8 6.2 1.6 1 0 0 1 1 1 1 WSC domain Apo-CIII PF05778.12 ETS81824.1 - 3.2 7.5 3.7 54 3.5 0.0 2.7 3 0 0 3 3 3 0 Apolipoprotein CIII (Apo-CIII) CarbpepA_inh PF02977.15 ETS81824.1 - 5 7.0 15.2 19 5.2 7.8 2.9 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Pec_lyase_C PF00544.19 ETS81825.1 - 5.9e-16 58.7 9.4 1.8e-14 53.8 9.4 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 ETS81825.1 - 2.3e-05 24.3 24.1 0.00055 19.8 11.4 2.3 1 1 1 2 2 2 2 Right handed beta helix region RRM_1 PF00076.22 ETS81826.1 - 8.1e-05 22.4 0.0 0.0025 17.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FKBP_C PF00254.28 ETS81828.1 - 2.3e-34 117.6 0.0 3.2e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TrkH PF02386.16 ETS81829.1 - 4.4e-98 328.9 5.8 1.6e-95 320.4 0.1 2.1 2 0 0 2 2 2 2 Cation transport protein Ion_trans_2 PF07885.16 ETS81829.1 - 1.6 8.7 9.7 0.25 11.3 4.8 2.3 2 0 0 2 2 2 0 Ion channel IMS PF00817.20 ETS81830.1 - 1.1e-43 148.8 0.1 2.7e-43 147.6 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 ETS81830.1 - 1.1e-14 55.1 0.1 3.6e-14 53.5 0.1 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 ETS81830.1 - 0.00011 22.3 0.0 0.00026 21.1 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif AMP-binding PF00501.28 ETS81832.1 - 1.3e-25 89.9 0.0 3.5e-24 85.2 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ETS81832.1 - 5e-24 84.9 0.0 7.8e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 ETS81832.1 - 3.9e-10 39.6 0.0 3.6e-09 36.4 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 ETS81832.1 - 2.3e-06 27.8 0.0 1.7e-05 25.1 0.0 2.6 3 0 0 3 3 3 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.24 ETS81832.1 - 0.0037 17.7 0.0 0.014 15.8 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 ETS81832.1 - 0.013 14.9 0.0 0.59 9.5 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ETS81832.1 - 0.026 13.5 0.0 5.2 6.0 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family BNR_2 PF13088.6 ETS81833.1 - 7.8e-12 45.1 0.1 1.1e-09 38.0 0.1 2.4 2 1 0 2 2 2 2 BNR repeat-like domain BNR PF02012.20 ETS81833.1 - 6.8e-09 34.4 5.5 0.043 13.8 0.1 4.9 4 0 0 4 4 4 3 BNR/Asp-box repeat Paired_CXXCH_1 PF09699.10 ETS81833.1 - 0.0027 17.4 0.7 2.7 7.8 0.3 2.5 2 0 0 2 2 2 2 Doubled CXXCH motif (Paired_CXXCH_1) Sortilin-Vps10 PF15902.5 ETS81833.1 - 0.052 12.3 0.4 17 4.1 0.3 3.4 3 1 1 4 4 4 0 Sortilin, neurotensin receptor 3, Anth_Ig PF05587.13 ETS81833.1 - 0.098 13.0 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Anthrax receptor extracellular domain p450 PF00067.22 ETS81834.1 - 2e-69 234.5 0.0 2.5e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3112 PF11309.8 ETS81835.1 - 1.9e-10 40.6 0.4 1.9e-10 40.6 0.4 2.9 2 2 1 4 4 4 2 Protein of unknown function (DUF3112) adh_short PF00106.25 ETS81836.1 - 2e-38 131.9 0.1 2.6e-38 131.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS81836.1 - 1.7e-36 125.9 0.0 2.2e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS81836.1 - 4.1e-14 52.9 0.1 6.9e-14 52.2 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ETS81836.1 - 0.0057 16.1 0.0 0.0081 15.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 ETS81836.1 - 0.11 11.7 0.0 0.31 10.3 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3835 PF12927.7 ETS81837.1 - 2.8e-27 95.4 0.6 2.8e-27 95.4 0.6 4.3 3 2 1 4 4 4 1 Domain of unknown function (DUF3835) Prefoldin_3 PF13758.6 ETS81837.1 - 7.5e-23 80.5 0.5 2.4e-22 78.9 0.5 1.9 1 0 0 1 1 1 1 Prefoldin subunit Rootletin PF15035.6 ETS81837.1 - 0.31 11.0 9.2 4.4 7.3 3.1 3.5 2 1 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Prefoldin_2 PF01920.20 ETS81837.1 - 0.92 9.5 5.4 14 5.7 0.1 3.4 3 0 0 3 3 3 0 Prefoldin subunit DivIC PF04977.15 ETS81837.1 - 1.2 9.0 3.7 4.1 7.2 3.7 2.0 1 0 0 1 1 1 0 Septum formation initiator CS PF04969.16 ETS81838.1 - 1.5e-17 64.3 0.1 2.9e-17 63.5 0.1 1.5 1 0 0 1 1 1 1 CS domain HMMR_C PF15908.5 ETS81838.1 - 0.02 15.2 0.1 0.037 14.3 0.1 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal MAT1 PF06391.13 ETS81839.1 - 4.4e-36 124.6 6.9 5.5e-36 124.3 6.9 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 ETS81839.1 - 3.1e-25 87.8 10.0 4.7e-25 87.2 10.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ETS81839.1 - 0.00039 20.2 4.8 0.00089 19.1 4.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ETS81839.1 - 0.0022 17.8 5.7 0.004 17.0 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS81839.1 - 0.0026 17.6 6.5 0.0043 16.9 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ETS81839.1 - 0.036 14.4 7.5 0.056 13.8 7.5 1.3 1 0 0 1 1 1 0 Ring finger domain zf-UDP PF14569.6 ETS81839.1 - 0.055 13.6 2.6 0.12 12.5 2.6 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger MRP-S26 PF14943.6 ETS81839.1 - 0.17 11.8 13.9 0.28 11.1 13.9 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF3797 PF12677.7 ETS81839.1 - 0.28 11.1 3.5 0.67 9.9 3.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-RING_UBOX PF13445.6 ETS81839.1 - 0.49 10.5 7.3 0.93 9.6 7.3 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 ETS81839.1 - 2.3 8.3 10.8 30 4.7 11.4 2.1 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 ETS81839.1 - 2.6 7.9 8.2 2.6 7.9 3.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain K_channel_TID PF07941.11 ETS81840.1 - 1.5 9.3 5.5 2.9 8.4 5.5 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain ANTH PF07651.16 ETS81842.1 - 1.6e-68 230.7 1.6 2.1e-68 230.3 1.6 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 ETS81842.1 - 3e-08 33.7 0.0 4.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 ENTH domain tRNA-synt_2 PF00152.20 ETS81843.1 - 4.3e-78 262.6 0.0 7.2e-78 261.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 ETS81843.1 - 0.021 14.3 0.1 0.13 11.7 0.1 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 ETS81843.1 - 0.034 14.1 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Transket_pyr PF02779.24 ETS81844.1 - 1.3e-45 155.2 0.0 1.8e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ETS81844.1 - 1.5e-34 118.5 0.0 5e-34 116.9 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain DUF460 PF04312.13 ETS81844.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Sterol_MT_C PF08498.10 ETS81845.1 - 2.8e-29 101.2 0.3 5.1e-29 100.4 0.3 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 ETS81845.1 - 1.9e-22 79.7 0.0 3.5e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS81845.1 - 2.3e-20 73.1 0.0 4.6e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS81845.1 - 2.7e-19 69.5 0.0 4e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ETS81845.1 - 2.1e-12 46.9 0.2 3e-12 46.4 0.2 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 ETS81845.1 - 8.2e-12 45.3 0.0 1.4e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS81845.1 - 2.8e-11 43.2 0.0 4.8e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ETS81845.1 - 4.1e-11 43.5 0.0 9.6e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ETS81845.1 - 0.00011 22.0 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 ETS81845.1 - 0.00035 20.2 0.0 0.00072 19.2 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_15 PF09445.10 ETS81845.1 - 0.00084 18.9 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 ETS81845.1 - 0.00095 18.8 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 ETS81845.1 - 0.001 18.2 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.16 ETS81845.1 - 0.0013 17.4 0.0 0.0018 16.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.6 ETS81845.1 - 0.0017 18.4 0.2 0.0033 17.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 ETS81845.1 - 0.0017 17.8 0.1 0.0062 16.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 ETS81845.1 - 0.0058 16.0 0.1 0.013 14.8 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase domain TehB PF03848.14 ETS81845.1 - 0.0096 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_24 PF13578.6 ETS81845.1 - 0.12 13.5 0.0 0.41 11.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MCR PF18509.1 ETS81847.1 - 3.2 7.4 11.8 0.061 12.9 1.4 3.4 3 0 0 3 3 3 0 Magnetochrome domain ORMDL PF04061.14 ETS81848.1 - 2.3e-59 199.1 3.1 2.7e-59 198.8 3.1 1.1 1 0 0 1 1 1 1 ORMDL family RIFIN PF02009.16 ETS81849.1 - 8.4 6.2 11.6 14 5.5 0.4 2.4 2 0 0 2 2 2 0 Rifin Methyltransf_3 PF01596.17 ETS81850.1 - 8.5e-28 97.0 0.0 5.8e-27 94.3 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 ETS81850.1 - 4.1e-10 40.6 0.0 1.2e-09 39.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 ETS81850.1 - 9.6e-10 38.6 0.0 1.3e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ETS81850.1 - 3.3e-08 33.5 0.0 4.6e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS81850.1 - 5.2e-06 27.1 0.0 9.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS81850.1 - 0.0049 17.5 0.0 0.0096 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS81850.1 - 0.01 16.6 0.0 0.018 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 ETS81850.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Abhydrolase_2 PF02230.16 ETS81851.1 - 0.2 11.4 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Ank_2 PF12796.7 ETS81853.1 - 9.2e-35 119.1 4.1 2.4e-05 24.8 0.0 10.4 4 2 5 10 10 10 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS81853.1 - 3.1e-18 65.9 10.1 0.044 14.4 0.0 11.8 8 4 5 13 13 13 4 Ankyrin repeats (many copies) Clr5 PF14420.6 ETS81853.1 - 2.7e-16 59.5 3.5 6.5e-16 58.3 3.5 1.7 1 0 0 1 1 1 1 Clr5 domain Ank_3 PF13606.6 ETS81853.1 - 4.4e-16 57.3 11.3 0.5 11.1 0.0 14.1 16 0 0 16 16 16 1 Ankyrin repeat Ank_5 PF13857.6 ETS81853.1 - 3e-12 46.5 4.6 1.2 9.6 0.0 10.0 8 2 3 11 11 11 3 Ankyrin repeats (many copies) Ank PF00023.30 ETS81853.1 - 0.001 19.4 15.6 7.5 7.2 0.0 10.0 11 0 0 11 11 11 1 Ankyrin repeat Gas_vesicle PF00741.18 ETS81853.1 - 3.4 7.9 4.9 3.5 7.9 0.4 3.0 3 0 0 3 3 3 0 Gas vesicle protein PQ-loop PF04193.14 ETS81856.1 - 0.02 14.6 0.5 0.071 12.9 0.5 1.9 1 0 0 1 1 1 0 PQ loop repeat VIT1 PF01988.19 ETS81856.1 - 1.6 8.5 4.6 2 8.2 3.6 1.7 1 1 0 1 1 1 0 VIT family DUF3021 PF11457.8 ETS81856.1 - 2.7 8.3 9.3 0.097 13.0 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) adh_short PF00106.25 ETS81857.1 - 5.2e-25 88.0 0.0 2.5e-18 66.2 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS81857.1 - 1.9e-14 53.8 0.1 1.4e-13 51.0 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS81857.1 - 0.00025 21.0 0.1 0.00043 20.3 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS81857.1 - 0.0087 15.2 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Presenilin PF01080.17 ETS81858.1 - 1.2 7.9 10.8 2 7.1 10.8 1.4 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 ETS81858.1 - 1.7 6.9 7.2 2.7 6.3 7.2 1.3 1 0 0 1 1 1 0 Menin Apt1 PF10351.9 ETS81858.1 - 2.6 6.8 9.2 3.7 6.3 9.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RR_TM4-6 PF06459.12 ETS81858.1 - 4.4 7.1 17.6 0.92 9.3 11.7 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 F-box-like PF12937.7 ETS81859.1 - 2e-07 30.8 0.2 5.2e-07 29.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS81859.1 - 4.4e-05 23.2 1.4 8.2e-05 22.4 1.4 1.5 1 0 0 1 1 1 1 F-box domain Cu-oxidase_3 PF07732.15 ETS81860.1 - 1.9e-37 127.9 0.8 1.3e-36 125.2 0.6 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ETS81860.1 - 2.3e-21 76.0 8.6 1e-17 64.2 0.7 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 ETS81860.1 - 3.1e-17 63.1 0.0 1.2e-16 61.2 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 ETS81861.1 - 9e-20 70.9 0.3 2.9e-19 69.2 0.3 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 ETS81861.1 - 1.1e-15 58.1 0.0 1.9e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ETS81861.1 - 4.3e-11 42.7 0.1 1.3e-06 28.1 0.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Zn_clus PF00172.18 ETS81862.1 - 1e-08 35.2 14.9 1.7e-08 34.5 14.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS81862.1 - 0.059 12.2 2.0 0.087 11.6 2.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 ETS81864.1 - 6.5e-56 189.8 0.4 8.7e-56 189.4 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS81864.1 - 2.7e-08 33.8 4.3 4.6e-08 33.1 4.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytidylate_kin PF02224.18 ETS81864.1 - 0.12 12.1 0.8 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase UPF0184 PF03670.13 ETS81864.1 - 0.23 11.8 1.4 0.44 11.0 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) SCP2 PF02036.17 ETS81865.1 - 6.3e-24 84.4 0.7 7.2e-24 84.2 0.7 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 ETS81865.1 - 4.8e-05 23.6 0.4 7.9e-05 22.9 0.3 1.4 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 ETS81865.1 - 0.025 15.0 0.1 0.03 14.7 0.1 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain Ran_BP1 PF00638.18 ETS81866.1 - 6.5e-13 49.0 0.0 1.2e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.6 ETS81866.1 - 2.2e-10 41.2 250.9 5.7e-08 33.5 16.5 13.5 2 1 9 11 11 11 7 Nucleoporin FG repeat region Abhydrolase_6 PF12697.7 ETS81867.1 - 5.3e-07 30.5 10.3 5.7e-06 27.1 10.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS81867.1 - 0.012 15.3 0.2 0.043 13.5 0.2 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold p450 PF00067.22 ETS81868.1 - 2.7e-38 131.9 0.0 1.8e-27 96.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 CorA PF01544.18 ETS81870.1 - 0.00025 20.5 6.2 0.00079 18.8 3.9 2.5 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Ank_2 PF12796.7 ETS81871.1 - 9.8e-35 119.0 1.9 1.4e-09 38.4 0.2 5.1 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS81871.1 - 2.2e-29 101.1 0.2 1.4e-08 34.8 0.0 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS81871.1 - 3.6e-27 94.4 0.5 7.4e-07 29.6 0.0 6.0 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 ETS81871.1 - 4.6e-25 86.9 0.3 0.00073 19.9 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 ETS81871.1 - 3.9e-24 82.1 0.2 0.0027 18.0 0.0 7.6 8 0 0 8 8 8 6 Ankyrin repeat CENP-B_dimeris PF09026.10 ETS81872.1 - 0.037 14.4 4.3 0.1 13.0 4.3 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNase_NucA_NucB PF14040.6 ETS81873.1 - 1.2e-16 61.1 2.7 2.6e-16 60.0 2.7 1.5 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Transketolase_N PF00456.21 ETS81875.1 - 2e-155 516.8 0.1 2.7e-155 516.4 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ETS81875.1 - 1.4e-46 158.4 0.0 2.5e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ETS81875.1 - 1.4e-11 44.3 0.0 2.8e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 ETS81875.1 - 0.00026 20.3 0.0 0.00048 19.4 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 ETS81875.1 - 0.0083 15.9 1.8 0.11 12.3 1.1 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ThiP_synth PF10120.9 ETS81875.1 - 0.026 14.1 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 Thiamine-phosphate synthase Glycos_transf_2 PF00535.26 ETS81875.1 - 0.13 12.0 0.1 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 COPIIcoated_ERV PF07970.12 ETS81876.1 - 2e-35 122.7 1.0 3e-35 122.1 0.8 1.4 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 ETS81876.1 - 2.2e-23 82.4 0.0 5e-23 81.3 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Tail_VII PF17091.5 ETS81876.1 - 0.54 10.2 2.7 1.6 8.6 2.7 1.7 1 0 0 1 1 1 0 Inovirus G7P protein Abhydrolase_6 PF12697.7 ETS81877.1 - 1.8e-08 35.3 2.1 1.8e-08 35.3 2.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS81877.1 - 1.2e-05 24.7 0.3 5.6e-05 22.5 0.1 2.1 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS81877.1 - 0.00024 20.8 0.1 0.00038 20.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold N_BRCA1_IG PF16158.5 ETS81879.1 - 2.8e-35 121.1 0.1 1.1e-34 119.2 0.1 2.1 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 ETS81879.1 - 7.2e-20 70.5 60.5 2.3e-06 27.3 8.9 4.6 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 ETS81879.1 - 0.48 10.8 49.7 0.32 11.4 6.4 4.6 4 0 0 4 4 4 0 C1 domain SF3b1 PF08920.10 ETS81879.1 - 1.5 9.3 5.3 1.1 9.8 0.5 3.0 2 0 0 2 2 2 0 Splicing factor 3B subunit 1 Btz PF09405.10 ETS81880.1 - 1.1e-27 96.9 2.1 3.3e-27 95.3 2.1 1.8 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Asp PF00026.23 ETS81881.1 - 6e-69 232.9 7.7 7.1e-69 232.6 7.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS81881.1 - 1e-14 55.2 9.0 2.8e-09 37.5 0.1 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ETS81881.1 - 7e-05 23.4 2.2 0.39 11.4 0.5 3.1 2 1 0 2 2 2 2 Aspartyl protease Aminotran_4 PF01063.19 ETS81882.1 - 1.8e-23 83.6 0.0 2.9e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV TPR_1 PF00515.28 ETS81883.1 - 4.9e-37 124.3 24.8 1.4e-05 24.7 0.0 11.6 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 ETS81883.1 - 5.5e-37 122.9 32.4 2.9e-05 23.8 0.0 11.4 12 0 0 12 12 11 9 Tetratricopeptide repeat TPR_17 PF13431.6 ETS81883.1 - 5e-23 79.8 7.2 0.0013 19.0 0.0 9.3 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 ETS81883.1 - 3.8e-21 74.5 23.9 0.00016 21.3 0.4 8.9 6 3 3 9 9 9 6 TPR repeat TPR_16 PF13432.6 ETS81883.1 - 4.6e-21 75.2 16.0 2.5e-05 24.8 0.6 7.9 7 1 1 8 8 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 ETS81883.1 - 1e-18 65.9 26.7 0.028 14.6 0.0 10.6 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 ETS81883.1 - 2.9e-15 56.3 29.4 0.0077 16.5 0.3 8.7 6 3 4 10 10 9 6 Tetratricopeptide repeat TPR_9 PF13371.6 ETS81883.1 - 2.8e-13 49.8 14.9 1.6e-06 28.2 1.3 6.3 5 3 3 8 8 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 ETS81883.1 - 1.3e-12 48.0 23.8 0.00093 19.7 0.6 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 ETS81883.1 - 1.1e-11 43.9 17.4 0.15 12.2 0.0 9.1 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 ETS81883.1 - 4.5e-09 36.4 26.1 0.1 13.5 0.5 8.9 6 2 4 10 10 9 4 Tetratricopeptide repeat TPR_10 PF13374.6 ETS81883.1 - 4.4e-08 32.7 25.7 0.18 11.8 0.3 9.2 9 0 0 9 9 9 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 ETS81883.1 - 1.4e-06 27.6 11.4 0.23 10.9 0.0 6.8 7 0 0 7 7 7 2 SHNi-TPR ANAPC3 PF12895.7 ETS81883.1 - 3.2e-06 27.3 17.5 0.037 14.2 0.6 5.6 3 2 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 ETS81883.1 - 4e-06 26.4 8.9 1.2e-05 24.9 1.4 2.9 1 1 1 2 2 2 1 MalT-like TPR region MAS20 PF02064.15 ETS81883.1 - 0.00019 21.5 12.7 0.013 15.6 1.0 4.7 4 1 1 5 5 5 1 MAS20 protein import receptor PknG_TPR PF16918.5 ETS81883.1 - 0.0094 14.7 1.0 0.047 12.4 0.1 2.4 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat Sel1 PF08238.12 ETS81883.1 - 0.036 14.8 1.1 9 7.1 0.1 4.1 3 0 0 3 3 3 0 Sel1 repeat HrpB1_HrpK PF09613.10 ETS81883.1 - 0.039 13.6 1.5 0.53 9.9 0.4 2.7 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) preATP-grasp_3 PF18301.1 ETS81883.1 - 0.044 14.1 0.1 0.31 11.3 0.1 2.4 2 0 0 2 2 2 0 pre ATP-grasp 3 domain NARP1 PF12569.8 ETS81883.1 - 0.047 12.6 22.4 0.047 12.6 0.8 4.8 3 1 2 5 5 5 0 NMDA receptor-regulated protein 1 Usp PF00582.26 ETS81883.1 - 0.058 13.9 7.0 14 6.2 2.0 3.6 3 0 0 3 3 3 0 Universal stress protein family Glyco_hyd_65N_2 PF14498.6 ETS81883.1 - 0.091 12.6 0.4 0.41 10.5 0.1 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, N-terminal domain TAF1_subA PF14929.6 ETS81883.1 - 0.9 8.9 5.4 0.91 8.9 1.3 2.7 2 1 0 2 2 2 0 TAF RNA Polymerase I subunit A MIT PF04212.18 ETS81883.1 - 7.8 6.6 19.9 45 4.2 0.7 7.1 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain AhpC-TSA_2 PF13911.6 ETS81884.1 - 6.2e-15 55.3 0.0 1.7e-14 53.9 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 ETS81884.1 - 0.00035 20.5 0.0 0.00066 19.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ETS81884.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Redoxin SEC-C PF02810.15 ETS81885.1 - 1.8e-08 34.1 10.2 3e-08 33.4 10.2 1.4 1 0 0 1 1 1 1 SEC-C motif DUF166 PF02593.14 ETS81885.1 - 0.00017 21.2 0.7 0.0002 21.0 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF1_Zn_bind PF09416.10 ETS81886.1 - 1.9e-71 239.0 1.8 1.6e-70 236.0 0.6 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 ETS81886.1 - 1.1e-59 201.4 0.0 1.7e-59 200.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ETS81886.1 - 3e-52 178.0 1.4 3.9e-29 102.2 0.1 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 ETS81886.1 - 1.8e-33 114.6 0.0 3.4e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 ETS81886.1 - 2e-13 50.5 0.1 4.5e-12 46.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ETS81886.1 - 1.6e-10 41.5 0.1 1.2e-09 38.7 0.0 2.5 2 2 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 ETS81886.1 - 2.4e-05 24.2 0.0 0.51 10.0 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 ETS81886.1 - 3e-05 24.1 0.0 5.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 ETS81886.1 - 4.7e-05 23.3 0.0 9.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.9 ETS81886.1 - 0.0011 18.3 0.1 0.03 13.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 ETS81886.1 - 0.0022 17.2 0.1 0.57 9.3 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase UvrD-helicase PF00580.21 ETS81886.1 - 0.0033 17.0 0.0 0.08 12.5 0.0 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 ETS81886.1 - 0.0042 16.9 0.0 0.0084 15.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ETS81886.1 - 0.0088 16.3 0.0 0.029 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 ETS81886.1 - 0.03 13.9 0.0 0.074 12.7 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 ETS81886.1 - 0.045 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.7 ETS81886.1 - 0.055 12.4 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ATPase PF06745.13 ETS81886.1 - 0.066 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 ETS81886.1 - 0.093 12.2 0.0 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Brix PF04427.18 ETS81887.1 - 4.4e-32 111.7 0.1 5.6e-32 111.4 0.1 1.1 1 0 0 1 1 1 1 Brix domain Syntaxin PF00804.25 ETS81888.1 - 1.2e-22 80.6 9.0 1.5e-22 80.2 9.0 1.1 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 ETS81888.1 - 2e-10 40.5 0.4 5.6e-10 39.1 0.4 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 ETS81888.1 - 0.0016 18.7 5.0 0.0016 18.7 5.0 2.2 2 0 0 2 2 2 1 Syntaxin-like protein PBP1_TM PF14812.6 ETS81888.1 - 0.0069 16.7 3.2 0.011 16.1 0.0 2.2 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal LMBR1 PF04791.16 ETS81888.1 - 0.02 13.8 1.5 0.024 13.6 1.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Allexi_40kDa PF05549.11 ETS81888.1 - 0.03 13.8 4.5 0.071 12.6 0.8 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF2207 PF09972.9 ETS81888.1 - 0.076 11.8 0.1 0.65 8.7 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Herpes_US9 PF06072.11 ETS81888.1 - 0.16 11.8 0.3 0.92 9.4 0.1 2.2 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 SKA1 PF07160.12 ETS81888.1 - 0.18 11.6 7.3 0.14 12.0 0.4 2.4 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF1349 PF07081.11 ETS81889.1 - 6e-12 45.6 0.0 5e-11 42.7 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) FUSC_2 PF13515.6 ETS81890.1 - 5.7e-29 100.8 7.3 5.7e-29 100.8 7.3 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 ETS81890.1 - 1.7e-05 24.8 0.2 9.7e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC PF04632.12 ETS81890.1 - 0.0013 17.4 13.5 0.98 7.9 12.0 3.5 2 1 0 2 2 2 2 Fusaric acid resistance protein family ALMT PF11744.8 ETS81890.1 - 0.0017 17.2 19.3 0.069 12.0 14.8 3.9 3 1 0 3 3 3 1 Aluminium activated malate transporter CPP1-like PF11833.8 ETS81890.1 - 0.0048 16.6 0.7 0.0048 16.6 0.7 2.6 2 1 0 2 2 2 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF485 PF04341.12 ETS81890.1 - 0.25 11.3 2.7 1.4 8.9 2.7 2.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DUF5308 PF17233.2 ETS81891.1 - 3.6e-52 176.9 7.8 4.1e-52 176.7 7.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5308) DUF3147 PF11345.8 ETS81892.1 - 0.039 14.3 0.3 0.039 14.3 0.3 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3147) CPP1-like PF11833.8 ETS81892.1 - 0.16 11.7 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Tyrosinase PF00264.20 ETS81893.1 - 1.8e-31 110.2 6.2 6.3e-31 108.4 6.2 1.8 1 1 0 1 1 1 1 Common central domain of tyrosinase AAT PF03417.16 ETS81894.1 - 6.3e-29 101.3 0.0 7.7e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase TFIIS_M PF07500.14 ETS81895.1 - 3.1e-28 98.5 1.6 3.8e-28 98.2 0.3 1.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 ETS81895.1 - 8e-18 64.0 7.2 1.3e-17 63.3 7.2 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 ETS81895.1 - 2.4e-10 40.3 1.1 6.3e-10 38.9 1.1 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Siah-Interact_N PF09032.11 ETS81895.1 - 0.59 10.5 8.5 2.7 8.3 3.0 2.6 2 1 0 2 2 2 0 Siah interacting protein, N terminal Sgf11 PF08209.11 ETS81895.1 - 3.4 7.3 6.0 11 5.7 1.5 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) PALP PF00291.25 ETS81896.1 - 2.9e-60 204.2 1.7 3.6e-60 203.9 1.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.17 ETS81897.1 - 1e-41 143.3 0.0 1.5e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 ETS81897.1 - 9.2e-06 25.6 0.0 4.3e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase FAD_SOX PF18371.1 ETS81897.1 - 0.087 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase MFS_1 PF07690.16 ETS81898.1 - 1.3e-42 146.0 28.2 1.3e-42 146.0 28.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS81898.1 - 3e-17 62.6 7.7 3e-17 62.6 7.7 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 ETS81898.1 - 2e-09 36.4 3.3 3.6e-09 35.6 3.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 ETS81898.1 - 0.00025 19.5 2.7 0.00062 18.2 2.7 1.6 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family UNC-93 PF05978.16 ETS81898.1 - 0.33 10.7 6.8 0.024 14.4 1.5 1.8 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 ETS81898.1 - 1.3 7.9 15.8 0.46 9.3 1.2 2.5 2 0 0 2 2 2 0 MFS_1 like family ADH_N PF08240.12 ETS81899.1 - 5e-27 93.9 3.5 5e-27 93.9 3.5 1.9 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS81899.1 - 4.2e-17 62.4 0.0 6.6e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS81899.1 - 9.2e-06 25.3 1.0 0.0036 16.8 0.4 2.6 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ATP-synt_G PF04718.15 ETS81900.1 - 4.1e-35 120.6 1.5 4.1e-35 120.6 1.5 1.9 2 1 0 2 2 2 1 Mitochondrial ATP synthase g subunit SipA_VBS PF17985.1 ETS81900.1 - 0.0053 16.6 0.1 0.0053 16.6 0.1 2.9 3 1 0 3 3 3 1 SipA vinculin binding site Alanine_zipper PF11839.8 ETS81900.1 - 0.63 10.4 16.6 4.9 7.6 0.9 2.3 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Methyltransf_23 PF13489.6 ETS81901.1 - 1.3e-15 57.6 0.0 3.9e-15 56.1 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS81901.1 - 7.9e-14 52.1 0.0 2.2e-13 50.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS81901.1 - 8.1e-11 42.4 0.0 2.3e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS81901.1 - 4.5e-09 36.3 0.0 3.9e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS81901.1 - 1.2e-05 26.0 0.0 4.2e-05 24.2 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS81901.1 - 0.00017 21.0 0.0 0.00053 19.4 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ETS81901.1 - 0.0014 18.2 0.0 0.0031 17.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 ETS81901.1 - 0.0068 16.5 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 ETS81901.1 - 0.034 13.6 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 ETS81901.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 ETS81901.1 - 0.15 11.4 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 ETS81901.1 - 0.18 11.0 0.0 0.33 10.2 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase TFIIA PF03153.13 ETS81902.1 - 3.3e-83 281.0 15.6 4e-83 280.7 15.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 ETS81902.1 - 0.43 10.3 13.3 1 9.0 13.3 1.6 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SOG2 PF10428.9 ETS81902.1 - 0.97 8.5 9.7 1.4 8.0 9.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DNA_pol_phi PF04931.13 ETS81902.1 - 3.5 5.6 8.4 5.1 5.1 8.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi HIG_1_N PF04588.13 ETS81903.1 - 1.4e-06 28.5 1.8 1.4e-06 28.5 1.8 2.0 2 0 0 2 2 2 1 Hypoxia induced protein conserved region IRK_N PF08466.10 ETS81903.1 - 0.11 12.7 0.1 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Inward rectifier potassium channel N-terminal Motilin_ghrelin PF04644.12 ETS81903.1 - 0.19 11.5 4.5 0.11 12.4 1.3 2.2 2 0 0 2 2 2 0 Motilin/ghrelin zf-C2H2_aberr PF17017.5 ETS81904.1 - 0.00026 21.2 3.0 0.013 15.6 0.0 2.3 2 0 0 2 2 2 1 Aberrant zinc-finger zf-C2H2_4 PF13894.6 ETS81904.1 - 0.0021 18.7 18.6 0.13 13.2 3.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ETS81904.1 - 0.0027 18.1 18.2 0.075 13.5 0.7 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ETS81904.1 - 0.025 15.0 2.0 0.025 15.0 2.0 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-CHCC PF10276.9 ETS81904.1 - 0.036 14.1 0.5 0.068 13.2 0.5 1.5 1 0 0 1 1 1 0 Zinc-finger domain zf_ZIC PF18366.1 ETS81904.1 - 0.047 13.8 0.8 0.44 10.7 0.0 2.3 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_jaz PF12171.8 ETS81904.1 - 0.053 13.8 6.8 0.59 10.5 2.4 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 ETS81904.1 - 0.41 10.7 3.6 1.6 8.8 0.3 2.5 2 0 0 2 2 2 0 BED zinc finger Kelch_4 PF13418.6 ETS81905.1 - 2.5e-29 101.0 6.3 1.1e-08 35.0 0.0 4.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 ETS81905.1 - 6.3e-23 80.2 2.1 9.7e-05 22.5 0.0 4.8 3 1 1 4 4 4 4 Kelch motif Kelch_5 PF13854.6 ETS81905.1 - 9.8e-23 79.7 4.3 1.5e-06 28.0 0.0 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 ETS81905.1 - 6e-21 73.8 0.0 6.9e-05 22.3 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 ETS81905.1 - 1.5e-19 69.8 3.0 8e-08 32.4 0.3 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 ETS81905.1 - 1e-17 63.3 2.7 0.0019 18.1 0.0 4.6 4 0 0 4 4 4 4 Kelch motif BTB PF00651.31 ETS81905.1 - 1.8e-09 37.8 0.0 3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.32 ETS81906.1 - 5.8e-18 64.9 16.6 0.00048 20.9 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS81906.1 - 2.3e-17 63.0 8.1 8.9e-06 25.9 0.4 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS81906.1 - 1.3e-06 27.7 0.1 0.00028 19.9 0.0 3.4 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ETS81906.1 - 3.4e-06 27.1 0.6 0.00062 19.7 0.2 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A COesterase PF00135.28 ETS81908.1 - 1.9e-81 274.5 0.0 2.3e-81 274.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS81908.1 - 4.1e-06 26.8 0.1 1.6e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS81908.1 - 0.021 14.3 0.5 0.031 13.7 0.5 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family MBOAT PF03062.19 ETS81909.1 - 4.7e-47 161.0 17.5 4.7e-47 161.0 17.5 2.2 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family SRRM_C PF15230.6 ETS81909.1 - 2.8 8.6 4.7 0.58 10.8 0.4 2.0 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus Baculo_PEP_C PF04513.12 ETS81911.1 - 0.07 13.2 0.7 0.17 11.9 0.7 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus F-box-like PF12937.7 ETS81912.1 - 7e-13 48.3 0.2 1.6e-12 47.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS81912.1 - 1.2e-05 25.0 0.2 3.1e-05 23.7 0.2 1.7 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 ETS81912.1 - 0.034 14.2 0.1 0.08 13.0 0.1 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain F-box_4 PF15966.5 ETS81912.1 - 0.064 13.1 0.1 0.28 11.1 0.1 2.1 2 0 0 2 2 2 0 F-box Lipocalin_9 PF17186.4 ETS81913.1 - 0.0076 16.5 0.2 0.0076 16.5 0.2 1.7 1 1 1 2 2 2 1 Lipocalin-like domain Fungal_trans PF04082.18 ETS81914.1 - 9.1e-21 74.1 0.3 1.6e-20 73.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS81914.1 - 8.4e-11 41.8 12.8 1.3e-10 41.2 12.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 ETS81915.1 - 4.6e-63 209.2 2.4 3.4e-20 71.8 0.1 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein UDG PF03167.19 ETS81916.1 - 6.8e-22 78.1 0.2 1.4e-21 77.1 0.0 1.5 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily DUF1708 PF08101.11 ETS81917.1 - 3.4e-174 580.0 0.0 5.2e-174 579.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF3533 PF12051.8 ETS81917.1 - 0.37 9.7 0.5 0.63 8.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) SET PF00856.28 ETS81918.1 - 4.5e-08 33.7 0.0 2.1e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 SET domain SRF-TF PF00319.18 ETS81919.1 - 1.3e-22 79.0 0.3 2e-22 78.4 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3591 PF12157.8 ETS81920.1 - 8e-138 459.8 3.3 2.6e-137 458.1 3.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 ETS81920.1 - 0.0019 18.0 0.9 0.0043 16.9 0.9 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 ETS81920.1 - 0.0058 16.6 0.8 0.01 15.9 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF2709 PF10915.8 ETS81920.1 - 0.041 13.1 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2709) SNARE PF05739.19 ETS81920.1 - 0.084 12.9 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 SNARE domain D-ser_dehydrat PF14031.6 ETS81921.1 - 2.4e-23 82.6 0.0 5.6e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 ETS81921.1 - 2.2e-16 60.2 0.0 3.3e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Syja_N PF02383.18 ETS81923.1 - 2.5e-84 283.3 0.0 3.2e-84 283.0 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Mitofilin PF09731.9 ETS81924.1 - 7.1e-152 507.4 22.8 2.8e-148 495.6 22.8 2.2 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Ras PF00071.22 ETS81924.1 - 6.4e-57 191.7 0.1 1.5e-56 190.5 0.1 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS81924.1 - 4.6e-35 120.4 0.1 1e-34 119.3 0.1 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS81924.1 - 9e-14 51.3 0.6 1.5e-13 50.6 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ETS81924.1 - 1.5e-05 24.6 1.7 4.3e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ETS81924.1 - 1.9e-05 24.2 0.0 3.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ETS81924.1 - 2.1e-05 24.6 0.0 4.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETS81924.1 - 0.00016 21.6 0.6 0.59 10.0 0.0 2.6 1 1 0 2 2 2 2 RsgA GTPase DUF2096 PF09869.9 ETS81924.1 - 0.18 11.9 5.0 0.28 11.2 2.1 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) AAA_16 PF13191.6 ETS81924.1 - 0.49 10.8 0.0 0.49 10.8 0.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain YlqD PF11068.8 ETS81924.1 - 5 7.5 14.9 34 4.8 9.2 2.7 1 1 1 2 2 2 0 YlqD protein PIG-P PF08510.12 ETS81925.1 - 1.3e-52 176.8 2.8 1.7e-52 176.4 2.8 1.1 1 0 0 1 1 1 1 PIG-P DUF4131 PF13567.6 ETS81925.1 - 0.043 13.5 0.9 0.069 12.8 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DPM2 PF07297.12 ETS81925.1 - 0.3 11.4 11.7 0.53 10.6 11.7 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Phage_holin_3_6 PF07332.11 ETS81925.1 - 0.96 9.5 4.9 1.4 9.0 4.9 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF485 PF04341.12 ETS81925.1 - 1.4 8.9 7.8 0.21 11.6 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Actin PF00022.19 ETS81926.1 - 8.2e-142 472.6 0.0 9.3e-142 472.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ETS81926.1 - 8.8e-07 28.0 0.2 0.019 13.8 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DUF423 PF04241.15 ETS81927.1 - 3.7e-29 100.8 0.6 6.1e-29 100.1 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF2721 PF11026.8 ETS81927.1 - 0.00084 19.2 0.3 0.00084 19.2 0.3 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2721) Memo PF01875.17 ETS81928.1 - 3.1e-74 249.6 0.0 3.5e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Kinesin PF00225.23 ETS81929.1 - 4.2e-108 361.2 1.0 8.1e-108 360.3 1.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ETS81929.1 - 5.4e-24 84.8 3.6 5.5e-24 84.8 0.1 2.9 3 0 0 3 3 3 1 Microtubule binding Microtub_bind PF13931.6 ETS81929.1 - 2.4e-08 34.5 0.0 2.4e-08 34.5 0.0 4.7 4 1 1 5 5 5 1 Kinesin-associated microtubule-binding TraC_F_IV PF11130.8 ETS81929.1 - 0.3 10.6 7.0 0.048 13.3 1.6 2.3 3 0 0 3 3 3 0 F pilus assembly Type-IV secretion system for plasmid transfer Prominin PF05478.11 ETS81929.1 - 0.63 7.9 32.2 0.025 12.6 6.5 3.1 1 1 1 3 3 3 0 Prominin Baculo_PEP_C PF04513.12 ETS81929.1 - 9.6 6.2 24.3 0.8 9.7 0.1 6.1 2 1 3 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0183 PF03676.14 ETS81930.1 - 4.9e-58 197.3 0.0 3.1e-34 118.9 0.0 3.8 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) Histidinol_dh PF00815.20 ETS81931.1 - 1.3e-160 534.9 2.3 1.9e-160 534.4 2.3 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 ETS81931.1 - 4e-24 84.2 0.1 8.3e-24 83.2 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 ETS81931.1 - 5e-13 49.3 0.1 1.5e-12 47.8 0.1 1.9 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Phage_TTP_13 PF16463.5 ETS81931.1 - 0.053 13.1 0.5 3.3 7.3 0.0 3.1 2 1 1 3 3 3 0 Phage tail tube protein family TFIID-31kDa PF02291.15 ETS81932.1 - 4.1e-40 136.6 0.0 5.3e-40 136.3 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit LNS2 PF08235.13 ETS81933.1 - 1.6e-93 312.4 0.0 2.1e-93 311.9 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 ETS81933.1 - 4e-42 142.3 0.0 1.6e-41 140.4 0.0 2.0 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 ETS81933.1 - 0.00048 19.8 0.0 0.21 11.2 0.0 3.1 3 0 0 3 3 3 2 HAD superfamily, subfamily IIIB (Acid phosphatase) MFS_1 PF07690.16 ETS81935.1 - 4.9e-26 91.5 60.3 1.3e-25 90.1 57.7 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Gram_pos_anchor PF00746.21 ETS81935.1 - 0.42 10.6 6.9 1.3 9.0 1.1 3.4 3 0 0 3 3 3 0 LPXTG cell wall anchor motif fn3 PF00041.21 ETS81936.1 - 3.5e-06 27.3 0.0 1e-05 25.8 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain AAA_13 PF13166.6 ETS81936.1 - 0.059 12.0 21.3 0.016 13.9 2.6 2.2 1 1 1 2 2 2 0 AAA domain Spc7 PF08317.11 ETS81936.1 - 0.19 10.6 35.3 0.033 13.1 20.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Cmc1 PF08583.10 ETS81937.1 - 4e-14 52.4 8.7 1e-13 51.1 8.7 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 ETS81937.1 - 0.0024 17.9 1.1 0.0037 17.2 1.1 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF559 PF04480.12 ETS81937.1 - 0.034 14.0 0.3 0.073 12.9 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF559) CHCH PF06747.13 ETS81937.1 - 0.047 13.8 1.6 0.2 11.8 1.5 1.9 1 1 2 3 3 3 0 CHCH domain GCK PF07802.11 ETS81937.1 - 0.056 13.9 1.8 0.11 12.9 1.8 1.5 1 0 0 1 1 1 0 GCK domain COX17 PF05051.13 ETS81937.1 - 0.082 13.3 1.2 0.72 10.3 0.1 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Glyco_hydro_106 PF17132.4 ETS81939.1 - 5.5e-20 71.3 0.1 1e-18 67.1 0.0 2.7 2 1 0 2 2 2 2 alpha-L-rhamnosidase MFS_1 PF07690.16 ETS81940.1 - 7.4e-35 120.5 31.7 1.4e-23 83.4 15.6 3.0 3 0 0 3 3 3 3 Major Facilitator Superfamily OATP PF03137.20 ETS81940.1 - 0.0082 14.5 8.3 1.7 6.8 0.2 3.8 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Adeno_E3 PF06040.11 ETS81940.1 - 0.15 12.3 3.7 0.11 12.7 0.4 2.3 2 0 0 2 2 2 0 Adenovirus E3 protein Bunya_RdRp PF04196.12 ETS81940.1 - 0.17 10.2 0.0 0.26 9.6 0.0 1.2 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase DUF2615 PF11027.8 ETS81940.1 - 2 8.6 0.0 2 8.6 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2615) DUF4231 PF14015.6 ETS81940.1 - 5 7.7 11.6 12 6.5 0.2 4.6 4 2 0 4 4 4 0 Protein of unknown function (DUF4231) F-box PF00646.33 ETS81941.1 - 0.012 15.4 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 F-box domain SET PF00856.28 ETS81942.1 - 2.7e-11 44.1 6.5 2.7e-10 40.9 5.8 2.7 1 1 0 1 1 1 1 SET domain MDD_C PF18376.1 ETS81942.1 - 0.055 13.2 0.4 0.11 12.2 0.1 1.7 2 0 0 2 2 2 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain ANAPC_CDC26 PF10471.9 ETS81944.1 - 5.6e-10 39.9 2.3 5.6e-10 39.9 2.3 4.6 4 1 1 5 5 5 2 Anaphase-promoting complex APC subunit CDC26 YL1 PF05764.13 ETS81944.1 - 0.0007 19.8 2.9 0.0007 19.8 2.9 2.1 2 0 0 2 2 2 1 YL1 nuclear protein Spt5_N PF11942.8 ETS81944.1 - 0.014 16.3 23.8 0.15 13.0 13.9 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Nop53 PF07767.11 ETS81944.1 - 0.041 13.3 16.0 0.041 13.3 6.0 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 ETS81944.1 - 0.11 10.8 19.0 0.043 12.1 9.0 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF719 PF05334.13 ETS81944.1 - 1.7 8.8 6.8 3.1 7.9 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF719) SDA1 PF05285.12 ETS81944.1 - 2.9 7.2 13.7 0.81 9.1 5.8 2.1 2 0 0 2 2 2 0 SDA1 Neur_chan_memb PF02932.16 ETS81944.1 - 5.6 6.9 10.7 5 7.1 1.8 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_M1_N PF17900.1 ETS81945.1 - 1.5e-08 35.1 0.0 0.00091 19.5 0.0 2.4 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 ETS81945.1 - 0.00037 20.1 0.5 0.00079 19.0 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M1 domain SAS4 PF15460.6 ETS81946.1 - 6.5e-30 103.2 0.1 2.4e-29 101.3 0.1 2.1 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 RNA_pol_3_Rpc31 PF11705.8 ETS81946.1 - 2.3e-06 28.1 6.7 2.3e-06 28.1 6.7 2.3 3 0 0 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 ETS81946.1 - 0.00068 19.2 17.6 0.0014 18.1 17.6 1.6 1 0 0 1 1 1 1 SDA1 TFB6 PF17110.5 ETS81946.1 - 0.13 12.0 2.2 0.32 10.7 2.2 1.7 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DNA_pol_phi PF04931.13 ETS81946.1 - 6.4 4.8 26.3 9.2 4.2 26.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Amidase PF01425.21 ETS81947.1 - 6e-33 114.5 0.5 9e-33 113.9 0.5 1.2 1 0 0 1 1 1 1 Amidase IQ PF00612.27 ETS81948.1 - 9.4e-05 21.9 0.8 0.00031 20.3 0.8 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF3246 PF11596.8 ETS81948.1 - 0.12 11.8 0.8 0.23 10.9 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) AA_permease_2 PF13520.6 ETS81949.1 - 5.5e-48 163.8 50.6 7.2e-48 163.5 50.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS81949.1 - 5.9e-26 91.1 43.1 8.9e-26 90.5 43.1 1.1 1 0 0 1 1 1 1 Amino acid permease PufQ PF05398.11 ETS81949.1 - 0.032 14.4 0.1 0.032 14.4 0.1 2.5 3 0 0 3 3 3 0 PufQ cytochrome subunit SecE PF00584.20 ETS81949.1 - 0.4 10.7 0.0 0.4 10.7 0.0 4.8 5 0 0 5 5 5 0 SecE/Sec61-gamma subunits of protein translocation complex ABC_membrane_2 PF06472.15 ETS81951.1 - 2.9e-94 315.5 0.1 1.6e-92 309.7 0.0 2.4 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 ETS81951.1 - 3.2e-15 56.8 0.0 8.2e-15 55.5 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 ETS81951.1 - 0.0022 18.6 0.9 1.1 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain End3 PF12761.7 ETS81951.1 - 0.018 15.3 1.1 0.07 13.3 1.3 1.7 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 AAA_16 PF13191.6 ETS81951.1 - 0.018 15.4 0.8 0.038 14.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ALIX_LYPXL_bnd PF13949.6 ETS81951.1 - 0.052 12.9 0.2 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Mg_chelatase PF01078.21 ETS81951.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_21 PF13304.6 ETS81951.1 - 0.075 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ETS81951.1 - 0.085 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 ETS81951.1 - 0.097 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 ETS81951.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ETS81951.1 - 0.18 11.3 0.0 0.41 10.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NIF PF03031.18 ETS81952.1 - 3.8e-54 182.7 0.4 5.1e-54 182.3 0.4 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CPSF_A PF03178.15 ETS81953.1 - 1.5e-84 284.1 0.0 3e-84 283.1 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 ETS81953.1 - 7.1e-21 74.4 0.0 1.2e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term F-box PF00646.33 ETS81954.1 - 0.018 14.9 0.3 0.07 13.0 0.0 2.1 2 0 0 2 2 2 0 F-box domain RNA_pol_Rpb1_1 PF04997.12 ETS81956.1 - 4.7e-110 367.8 0.2 7.4e-110 367.1 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 ETS81956.1 - 1.1e-98 329.9 0.1 1.9e-98 329.2 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 ETS81956.1 - 7.3e-76 254.0 0.0 1.6e-75 252.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 ETS81956.1 - 8.4e-57 192.1 1.5 1.7e-56 191.1 1.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 ETS81956.1 - 1.1e-43 149.0 0.0 2.7e-43 147.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 ETS81956.1 - 4.6e-40 136.7 3.3 8.7e-40 135.8 2.2 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 ETS81956.1 - 1.2e-36 124.9 0.1 3e-36 123.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 ETS81956.1 - 0.0012 19.0 189.7 0.12 12.8 10.1 13.1 9 3 3 13 13 13 9 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.32 ETS81957.1 - 2.5e-15 56.6 3.9 5.4e-05 23.9 0.2 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS81957.1 - 5.4e-09 36.2 0.6 0.0016 18.7 0.0 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ETS81957.1 - 5.8e-05 23.1 0.2 0.18 11.6 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 ETS81957.1 - 0.0019 17.8 1.5 0.0049 16.5 0.8 2.2 2 1 0 2 2 2 1 PQQ-like domain Thg1 PF04446.12 ETS81958.1 - 4.9e-53 178.5 0.0 7.1e-53 177.9 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 ETS81958.1 - 3.5e-51 172.5 0.3 4.9e-51 172.0 0.3 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain DUF4692 PF15763.5 ETS81960.1 - 1.3 9.4 5.3 2.1 8.8 0.4 2.3 1 1 1 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Apt1 PF10351.9 ETS81961.1 - 0.067 12.0 7.2 0.074 11.9 7.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain UDG PF03167.19 ETS81962.1 - 1.3e-19 70.7 0.0 2e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily UDPGP PF01704.18 ETS81963.1 - 1.2e-43 149.3 0.0 2.2e-42 145.2 0.0 2.1 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 ETS81963.1 - 0.08 13.3 0.0 0.21 12.0 0.0 1.7 2 0 0 2 2 2 0 MobA-like NTP transferase domain Ribophorin_II PF05817.14 ETS81964.1 - 1.8e-34 119.3 0.0 2.1e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II SDA1 PF05285.12 ETS81966.1 - 0.007 15.8 3.1 0.0079 15.7 3.1 1.1 1 0 0 1 1 1 1 SDA1 DUF1656 PF07869.12 ETS81966.1 - 0.14 12.2 3.8 0.3 11.1 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) CENP-B_dimeris PF09026.10 ETS81966.1 - 1.8 9.0 9.4 3.5 8.1 9.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 ETS81966.1 - 3.9 5.4 9.0 5.2 5.0 9.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Bromodomain PF00439.25 ETS81967.1 - 2.9e-25 88.1 1.6 5e-25 87.4 0.9 1.8 2 0 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.25 ETS81967.1 - 6.6e-08 32.8 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS81967.1 - 7.2e-07 29.2 0.2 1.7e-06 28.0 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS81967.1 - 0.00028 21.2 0.3 0.00061 20.2 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Ost5 PF05251.12 ETS81968.1 - 1.6e-17 63.5 10.1 1.8e-17 63.4 10.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 DUF2627 PF11118.8 ETS81968.1 - 0.0063 17.1 0.2 0.0063 17.1 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2627) PEP-CTERM PF07589.11 ETS81968.1 - 1.8 8.8 6.5 4.2 7.6 3.7 2.7 2 1 0 2 2 2 0 PEP-CTERM motif Rad1 PF02144.16 ETS81969.1 - 8.5e-77 257.9 0.0 9.7e-77 257.7 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PX PF00787.24 ETS81973.1 - 2.4e-20 72.6 0.0 3.9e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 PX domain Hamartin PF04388.12 ETS81973.1 - 0.53 8.9 2.2 0.67 8.6 2.2 1.0 1 0 0 1 1 1 0 Hamartin protein Mpv17_PMP22 PF04117.12 ETS81974.1 - 1.3e-23 82.9 0.2 2.3e-23 82.2 0.2 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Peptidase_M28 PF04389.17 ETS81975.1 - 3.9e-35 121.4 0.0 5.6e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 CDP-OH_P_transf PF01066.21 ETS81976.1 - 8.5e-16 58.5 0.4 8.5e-16 58.5 0.4 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Glyco_hydro_43 PF04616.14 ETS81978.1 - 6.5e-34 117.6 1.8 8e-34 117.3 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 LSM PF01423.22 ETS81979.1 - 2.3e-12 46.4 0.0 3.3e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ETS81979.1 - 0.014 15.5 0.0 0.022 14.9 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain DUF3072 PF11272.8 ETS81979.1 - 0.83 9.6 5.7 5.5 7.0 1.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3072) XPG_N PF00752.17 ETS81980.1 - 1.2e-33 115.6 0.0 3.1e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 ETS81980.1 - 1.6e-26 92.5 0.0 5.1e-26 90.9 0.0 2.0 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 ETS81980.1 - 0.0017 18.1 3.6 0.015 15.2 3.6 2.8 1 0 0 1 1 1 1 Ubiquitin interaction motif 5_3_exonuc PF01367.20 ETS81980.1 - 0.0065 17.1 0.5 0.026 15.1 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Glucodextran_B PF09136.10 ETS81980.1 - 1.8 9.0 3.7 2.3 8.6 0.3 2.5 2 0 0 2 2 2 0 Glucodextranase, domain B CTV_P6 PF06706.11 ETS81982.1 - 0.005 16.5 1.8 0.025 14.3 1.8 2.2 1 0 0 1 1 1 1 Citrus tristeza virus 6-kDa protein DUF1980 PF09323.10 ETS81982.1 - 0.2 11.6 1.2 0.51 10.2 1.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Sigma_reg_N PF13800.6 ETS81982.1 - 1.5 9.1 6.0 0.64 10.4 0.2 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Aldedh PF00171.22 ETS81983.1 - 1.1e-131 439.6 0.2 1.3e-131 439.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2309 PF10070.9 ETS81983.1 - 0.12 10.7 0.0 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) adh_short_C2 PF13561.6 ETS81985.1 - 2.3e-52 177.9 0.4 3.4e-52 177.3 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS81985.1 - 5.5e-44 150.0 2.2 7e-44 149.6 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS81985.1 - 4.2e-12 46.3 1.2 6.7e-12 45.7 1.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS81985.1 - 0.044 13.2 0.9 0.069 12.6 0.9 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_8 PF13450.6 ETS81985.1 - 0.11 12.7 0.1 0.32 11.2 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_43 PF04616.14 ETS81986.1 - 3.3e-52 177.6 1.3 4.5e-52 177.2 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ETS81986.1 - 2.4e-29 102.5 0.0 1.2e-28 100.3 0.0 1.9 1 1 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF1467 PF07330.12 ETS81986.1 - 0.19 11.7 0.1 0.52 10.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) LMBR1 PF04791.16 ETS81987.1 - 2.3e-17 63.1 2.6 2.3e-17 63.1 2.6 2.5 2 1 1 3 3 3 2 LMBR1-like membrane protein Arc_PepC_II PF06847.11 ETS81987.1 - 0.19 12.3 0.6 0.73 10.4 0.6 2.0 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II DUF3671 PF12420.8 ETS81987.1 - 0.99 9.5 0.0 0.99 9.5 0.0 3.5 4 1 0 4 4 4 0 Protein of unknown function HSP70 PF00012.20 ETS81988.1 - 6.3e-226 751.2 7.2 7e-226 751.1 7.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ETS81988.1 - 2.5e-16 59.4 0.2 4.5e-15 55.3 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 ETS81988.1 - 0.00025 20.9 0.0 0.0005 19.8 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 ETS81988.1 - 0.21 12.0 2.4 39 4.7 0.1 3.6 3 2 0 3 3 3 0 Cell division protein FtsA Bromodomain PF00439.25 ETS81989.1 - 4.5e-33 113.2 0.3 3.8e-15 55.7 0.0 2.4 2 0 0 2 2 2 2 Bromodomain SDA1 PF05285.12 ETS81989.1 - 0.00066 19.2 12.0 0.00091 18.7 12.0 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 ETS81989.1 - 0.0012 17.1 11.1 0.0019 16.5 11.1 1.2 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.12 ETS81989.1 - 0.0043 15.6 13.6 0.0062 15.0 13.6 1.2 1 0 0 1 1 1 1 Mpp10 protein CobT PF06213.12 ETS81989.1 - 0.027 13.9 15.6 0.044 13.2 15.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 ETS81989.1 - 0.036 12.4 12.1 0.051 11.9 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 ETS81989.1 - 0.053 13.6 15.9 0.11 12.6 15.9 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Nha1_C PF08619.10 ETS81989.1 - 0.092 11.9 19.0 0.19 10.9 19.0 1.5 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Paf1 PF03985.13 ETS81989.1 - 0.15 11.0 16.2 0.25 10.3 16.2 1.3 1 0 0 1 1 1 0 Paf1 Cwf_Cwc_15 PF04889.12 ETS81989.1 - 0.56 9.9 13.7 1.3 8.7 13.7 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Tim54 PF11711.8 ETS81989.1 - 0.67 8.7 8.7 1.4 7.6 8.7 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Na_trans_assoc PF06512.13 ETS81989.1 - 0.92 9.8 11.2 1.9 8.8 11.2 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated DNA_pol_phi PF04931.13 ETS81989.1 - 1.1 7.2 25.1 2.1 6.4 25.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi PPP4R2 PF09184.11 ETS81989.1 - 1.2 8.7 14.9 2.6 7.6 14.9 1.5 1 0 0 1 1 1 0 PPP4R2 DUF913 PF06025.12 ETS81989.1 - 1.3 8.0 4.7 2.6 6.9 4.7 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 ETS81989.1 - 1.7 8.8 5.3 5.8 7.1 5.3 2.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RPN2_C PF18004.1 ETS81989.1 - 3.3 7.6 10.6 7.7 6.4 10.6 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PTPRCAP PF15713.5 ETS81989.1 - 3.4 7.9 20.1 7.9 6.8 20.1 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RR_TM4-6 PF06459.12 ETS81989.1 - 3.6 7.3 12.3 10 5.8 12.3 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 rRNA_processing PF08524.11 ETS81989.1 - 8.3 6.4 15.5 7.1 6.6 10.8 2.3 2 0 0 2 2 2 0 rRNA processing CKS PF01111.19 ETS81990.1 - 2.6e-32 110.9 0.9 4.1e-32 110.3 0.9 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit FSIP1 PF15554.6 ETS81990.1 - 0.18 10.9 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 FSIP1 family ERO1 PF04137.15 ETS81991.1 - 7.6e-133 443.1 0.4 1.4e-132 442.3 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) HVSL PF09749.9 ETS81992.1 - 2.6e-79 266.1 0.0 3.1e-79 265.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein FTA2 PF13095.6 ETS81993.1 - 4.5e-49 167.0 0.0 6.2e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pal1 PF08316.11 ETS81994.1 - 7.6e-10 39.7 0.1 1.1e-09 39.2 0.1 1.5 1 1 0 1 1 1 1 Pal1 cell morphology protein Pil1 PF13805.6 ETS81995.1 - 4e-125 416.7 0.2 5e-125 416.3 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 APG6_N PF17675.1 ETS81995.1 - 4.7 7.7 11.6 12 6.4 1.5 2.9 1 1 2 3 3 3 0 Apg6 coiled-coil region EZH2_N PF18601.1 ETS81996.1 - 2.5e-34 117.4 0.2 6e-34 116.2 0.2 1.7 1 0 0 1 1 1 1 EZH2 N-terminal domain Ezh2_MCSS PF18600.1 ETS81996.1 - 3.5e-20 71.4 1.1 9.6e-20 70.0 1.1 1.8 1 0 0 1 1 1 1 MCSS domain SET PF00856.28 ETS81996.1 - 2e-15 57.6 0.1 2e-15 57.6 0.1 2.9 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 ETS81996.1 - 2.1e-05 24.9 33.2 4.5e-05 23.8 12.5 3.9 2 1 1 3 3 3 1 CXC domain DUF2140 PF09911.9 ETS81999.1 - 1.4 8.4 5.2 9.6 5.7 0.3 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2140) PsbI PF02532.14 ETS81999.1 - 3.2 7.8 6.2 0.32 11.0 0.4 2.5 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) PPP4R2 PF09184.11 ETS82000.1 - 1.8e-11 44.2 10.4 1.1e-08 35.0 0.0 2.4 2 0 0 2 2 2 2 PPP4R2 AAA_23 PF13476.6 ETS82001.1 - 1.7e-24 87.5 23.5 1.7e-24 87.5 23.5 7.7 2 1 2 4 4 3 1 AAA domain AAA_21 PF13304.6 ETS82001.1 - 2.5e-11 44.0 5.6 4.6e-05 23.4 0.0 3.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETS82001.1 - 4.4e-10 39.4 14.3 1.8e-06 27.6 0.0 3.0 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 ETS82001.1 - 3.5e-06 27.1 0.0 1.3e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 ETS82001.1 - 4.6e-05 23.3 67.8 7.7 6.1 20.5 5.4 1 1 1 2 2 1 1 AAA ATPase domain DUF3800 PF12686.7 ETS82001.1 - 0.00018 22.1 2.4 4.1 8.1 1.9 5.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3800) RasGAP_C PF03836.15 ETS82001.1 - 0.0015 18.7 8.2 0.0015 18.7 8.2 9.3 4 3 2 8 8 8 3 RasGAP C-terminus AAA_29 PF13555.6 ETS82001.1 - 0.0018 18.0 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ETS82001.1 - 0.043 14.2 0.0 0.043 14.2 0.0 5.1 3 2 1 5 5 4 0 AAA ATPase domain ABC_tran PF00005.27 ETS82001.1 - 0.088 13.3 0.0 0.088 13.3 0.0 6.7 3 2 0 4 4 2 0 ABC transporter AAA_13 PF13166.6 ETS82001.1 - 0.095 11.3 0.0 0.095 11.3 0.0 6.3 2 1 4 6 6 5 0 AAA domain SlyX PF04102.12 ETS82001.1 - 0.22 12.2 0.1 0.22 12.2 0.1 9.4 8 2 2 10 10 9 0 SlyX GATA PF00320.27 ETS82002.1 - 4.5e-16 58.2 5.4 9.2e-16 57.2 5.4 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 ETS82002.1 - 3.3e-12 46.5 0.0 7e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 ETS82002.1 - 8.3e-09 35.5 0.1 3.5e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 ETS82002.1 - 8.3e-06 25.9 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 ETS82002.1 - 0.0028 17.9 0.0 0.0064 16.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold Zn-ribbon_8 PF09723.10 ETS82002.1 - 0.0083 16.2 0.2 0.018 15.1 0.2 1.6 1 0 0 1 1 1 1 Zinc ribbon domain PAS_9 PF13426.7 ETS82002.1 - 0.0099 16.1 0.1 0.039 14.2 0.0 2.0 2 0 0 2 2 2 1 PAS domain TF_Zn_Ribbon PF08271.12 ETS82002.1 - 0.13 11.8 0.6 0.99 9.0 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DUF4428 PF14471.6 ETS82002.1 - 3.5 7.6 5.0 0.92 9.5 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) ECH_1 PF00378.20 ETS82003.1 - 1.5e-42 145.6 0.0 7.3e-42 143.4 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ETS82003.1 - 1.1e-24 87.6 0.0 2.9e-21 76.3 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Acetyltransf_1 PF00583.25 ETS82005.1 - 8.1e-10 39.0 0.0 1.2e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 ETS82005.1 - 1.8e-08 35.1 0.2 3.4e-08 34.3 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS82005.1 - 2.5e-05 24.6 0.0 4.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ETS82005.1 - 6.8e-05 23.1 0.2 0.00011 22.4 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS82005.1 - 0.0035 17.3 0.0 0.016 15.2 0.0 2.0 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 ETS82005.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RNase_P_p30 PF01876.16 ETS82006.1 - 2.5e-58 197.1 0.0 3.5e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 zinc_ribbon_15 PF17032.5 ETS82008.1 - 2.6e-05 24.9 0.4 3.9e-05 24.3 0.4 1.2 1 0 0 1 1 1 1 zinc-ribbon family PriA_CRR PF18319.1 ETS82008.1 - 0.62 10.1 0.1 0.62 10.1 0.1 2.5 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain Sugar_tr PF00083.24 ETS82010.1 - 7e-96 321.8 21.6 8e-96 321.6 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS82010.1 - 5e-11 42.1 39.6 2.3e-08 33.3 6.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4064 PF13273.6 ETS82011.1 - 0.086 13.1 6.0 0.17 12.2 4.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF4293 PF14126.6 ETS82011.1 - 0.44 10.8 5.0 0.63 10.3 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF1700 PF08006.11 ETS82011.1 - 9.9 5.7 6.4 19 4.7 4.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) DUF4448 PF14610.6 ETS82012.1 - 1.2e-49 168.7 1.0 1.6e-49 168.2 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) H2TH PF06831.14 ETS82012.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain DUF1776 PF08643.10 ETS82013.1 - 3.3e-107 358.3 0.0 4.1e-107 358.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) AIF-MLS PF14962.6 ETS82013.1 - 0.16 11.9 0.2 0.28 11.1 0.2 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence zf-CCCH PF00642.24 ETS82014.1 - 1.4e-23 82.3 27.5 7e-07 29.0 0.4 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ETS82014.1 - 6.1e-17 61.1 29.0 4.4e-06 26.6 2.5 5.5 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 ETS82014.1 - 1.3e-12 48.4 21.3 0.0019 18.9 0.3 5.4 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 ETS82014.1 - 1.7e-08 34.1 30.2 9.5e-05 22.1 0.2 5.5 5 0 0 5 5 5 4 CCCH-type zinc finger zf-C3H1 PF10650.9 ETS82014.1 - 0.22 11.3 11.6 1.2 8.9 1.0 4.4 4 0 0 4 4 4 0 Putative zinc-finger domain zf-CCCH_3 PF15663.5 ETS82014.1 - 2.7 8.2 15.5 1.1 9.5 1.4 3.3 1 1 3 4 4 4 0 Zinc-finger containing family Glyco_hydro_31 PF01055.26 ETS82015.1 - 1.3e-145 485.9 6.3 1.7e-145 485.6 6.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 ETS82015.1 - 1.6e-34 118.6 0.0 2.8e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Asp_Glu_race PF01177.22 ETS82016.1 - 1.1e-40 139.9 0.1 1.3e-40 139.7 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF2620 PF10941.8 ETS82016.1 - 0.11 12.7 0.3 2.7 8.2 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function DUF2620 HET PF06985.11 ETS82017.1 - 1.3e-32 113.2 0.0 2e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribonuc_L-PSP PF01042.21 ETS82018.1 - 5e-18 65.3 0.0 6e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF2509 PF10713.9 ETS82018.1 - 0.03 14.5 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2509) Methyltransf_25 PF13649.6 ETS82020.1 - 1e-15 58.2 0.0 4e-15 56.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS82020.1 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS82020.1 - 5.3e-13 49.4 0.0 5.4e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS82020.1 - 4.4e-11 43.4 0.0 8.3e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS82020.1 - 4.8e-09 36.0 0.0 7.7e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 ETS82020.1 - 2.8e-05 24.0 0.0 5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ETS82020.1 - 2.9e-05 24.1 0.0 4.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ETS82020.1 - 8.3e-05 22.4 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 ETS82020.1 - 0.00015 21.2 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 ETS82020.1 - 0.0031 16.6 0.0 0.0047 16.1 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PrmA PF06325.13 ETS82020.1 - 0.0056 16.1 0.0 0.0076 15.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 ETS82020.1 - 0.027 13.5 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CMAS PF02353.20 ETS82020.1 - 0.065 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase UPF0020 PF01170.18 ETS82020.1 - 0.087 12.5 0.0 1.8 8.2 0.0 2.2 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 ETS82020.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Amidase PF01425.21 ETS82021.1 - 2.8e-91 306.7 0.0 3.6e-91 306.4 0.0 1.1 1 0 0 1 1 1 1 Amidase Lactamase_B PF00753.27 ETS82022.1 - 9.4e-05 22.5 0.2 0.00021 21.4 0.2 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily zf-CRD PF17979.1 ETS82022.1 - 0.061 13.4 0.2 0.094 12.8 0.2 1.2 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions RecR PF02132.15 ETS82022.1 - 0.21 11.2 1.9 0.42 10.2 1.9 1.4 1 0 0 1 1 1 0 RecR protein ubiquitin PF00240.23 ETS82023.1 - 2.3e-18 65.7 0.0 4.3e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 ETS82023.1 - 1.3e-06 28.1 3.8 6e-06 26.0 0.0 2.7 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD_2 PF13881.6 ETS82023.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 ETS82023.1 - 0.0031 17.3 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ETS82023.1 - 0.0042 17.6 0.0 0.008 16.7 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain HOIP-UBA PF16678.5 ETS82023.1 - 0.019 15.0 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair ADH_zinc_N PF00107.26 ETS82024.1 - 2.8e-31 108.2 0.3 4.4e-31 107.6 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS82024.1 - 1.1e-11 45.9 0.0 2e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS82024.1 - 0.00013 21.8 0.0 0.00037 20.3 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 ETS82024.1 - 0.014 14.7 0.8 0.023 14.0 0.8 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 ETS82024.1 - 0.017 15.4 0.1 0.031 14.6 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 ETS82024.1 - 0.16 11.3 0.2 0.26 10.6 0.2 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain p450 PF00067.22 ETS82026.1 - 6.9e-56 189.9 0.0 8.8e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_tranf_2_3 PF13641.6 ETS82027.1 - 1.2e-17 64.5 0.2 1.2e-17 64.5 0.2 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ETS82027.1 - 4.3e-12 46.2 0.2 1.8e-11 44.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ETS82027.1 - 0.0005 19.6 0.1 0.0071 15.8 0.1 2.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Ank_2 PF12796.7 ETS82029.1 - 2.6e-43 146.5 14.8 3.5e-13 49.9 1.2 6.2 1 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS82029.1 - 5.7e-28 93.9 1.1 0.023 15.2 0.0 10.6 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.6 ETS82029.1 - 2.3e-27 95.0 7.8 1.7e-07 31.6 0.2 8.2 4 2 6 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS82029.1 - 5.7e-22 77.5 11.6 5.4e-05 23.4 0.7 8.8 4 2 6 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 ETS82029.1 - 3.4e-19 68.4 17.8 0.02 15.3 0.2 10.1 9 1 1 10 10 10 6 Ankyrin repeat NACHT PF05729.12 ETS82029.1 - 1.1e-10 41.7 0.0 3.5e-10 40.1 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ETS82029.1 - 0.0022 18.2 0.8 0.011 16.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS82029.1 - 0.0033 17.8 0.0 0.0033 17.8 0.0 3.4 4 0 0 4 4 4 1 AAA ATPase domain RTP PF02334.16 ETS82029.1 - 0.027 15.1 0.3 0.3 11.7 0.7 2.5 3 0 0 3 3 3 0 Replication terminator protein Ndc80_HEC PF03801.13 ETS82029.1 - 0.32 10.6 5.9 0.6 9.7 4.9 2.0 2 0 0 2 2 2 0 HEC/Ndc80p family zf-RING_2 PF13639.6 ETS82030.1 - 5.6e-11 42.6 1.7 1.2e-10 41.6 1.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ETS82030.1 - 1.2e-09 37.8 1.6 2.2e-09 36.9 1.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ETS82030.1 - 1.9e-08 34.0 1.4 4.1e-08 32.9 1.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ETS82030.1 - 1.8e-07 30.9 0.4 4.1e-07 29.8 0.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ETS82030.1 - 4.8e-06 26.8 5.4 4.5e-05 23.7 5.4 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ETS82030.1 - 1.1e-05 25.3 2.3 2.3e-05 24.3 2.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ETS82030.1 - 0.00012 21.9 0.9 0.00028 20.7 0.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ETS82030.1 - 0.00075 19.4 0.4 0.0014 18.5 0.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 ETS82030.1 - 0.0061 16.7 2.1 0.018 15.2 1.1 2.3 2 1 0 2 2 2 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 ETS82030.1 - 0.011 15.3 1.6 0.027 14.1 1.6 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 ETS82030.1 - 0.025 14.5 0.2 0.054 13.4 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ETS82030.1 - 0.034 14.2 1.4 0.15 12.1 1.4 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 ETS82030.1 - 0.038 14.2 0.8 0.1 12.8 0.8 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-HC5HC2H_2 PF13832.6 ETS82030.1 - 0.091 12.9 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain Vps39_2 PF10367.9 ETS82030.1 - 0.14 12.7 0.1 0.21 12.1 0.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 RINGv PF12906.7 ETS82030.1 - 2.8 8.1 5.3 3.1 8.0 2.3 2.3 1 1 1 2 2 2 0 RING-variant domain FAD_binding_3 PF01494.19 ETS82031.1 - 2.7e-20 72.9 0.1 4.9e-14 52.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 ETS82031.1 - 2.8e-05 23.9 0.1 0.00022 21.0 0.0 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS82031.1 - 2.8e-05 23.5 0.2 0.00032 20.0 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS82031.1 - 0.00015 20.9 0.2 0.00053 19.1 0.2 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ETS82031.1 - 0.00016 20.9 0.1 0.00058 19.0 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 ETS82031.1 - 0.00016 21.8 0.0 0.00038 20.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ETS82031.1 - 0.0018 17.7 0.1 0.024 13.9 0.0 2.2 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 ETS82031.1 - 0.0061 17.1 0.1 0.025 15.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS82031.1 - 0.0098 15.1 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 ETS82031.1 - 0.014 14.7 0.0 0.032 13.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PilO PF04350.13 ETS82031.1 - 0.061 13.5 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Pilus assembly protein, PilO PPDK_N PF01326.19 ETS82031.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain TrkA_N PF02254.18 ETS82031.1 - 0.16 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Aldolase_II PF00596.21 ETS82032.1 - 7.2e-29 101.0 0.8 8.8e-29 100.8 0.8 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF1115 PF06544.12 ETS82034.1 - 5.1e-11 42.9 0.0 8.8e-11 42.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) DUF1691 PF07950.11 ETS82035.1 - 7.5e-38 129.5 6.7 3.1e-31 108.3 4.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) zf-C2H2_jaz PF12171.8 ETS82036.1 - 1.4e-07 31.6 1.9 2.3e-07 30.9 1.9 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ETS82036.1 - 0.00013 22.3 0.7 0.00022 21.5 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 ETS82036.1 - 0.003 17.6 2.1 0.0053 16.9 2.1 1.4 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2 PF00096.26 ETS82036.1 - 0.04 14.4 0.7 0.069 13.6 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS82036.1 - 0.047 14.6 0.3 0.091 13.7 0.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ETS82036.1 - 0.068 13.5 0.5 0.11 12.9 0.5 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) 4HBT_3 PF13622.6 ETS82037.1 - 3.5e-47 161.8 0.1 4e-47 161.5 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily HET PF06985.11 ETS82038.1 - 6.6e-21 75.2 0.0 1.1e-20 74.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AP_endonuc_2 PF01261.24 ETS82040.1 - 0.083 12.3 0.0 0.17 11.3 0.0 1.5 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Cupin_2 PF07883.11 ETS82042.1 - 1.6e-07 30.9 0.0 2.9e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 ETS82042.1 - 0.0063 16.2 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Romo1 PF10247.9 ETS82043.1 - 0.00065 20.0 0.4 0.42 11.0 0.1 2.3 2 0 0 2 2 2 2 Reactive mitochondrial oxygen species modulator 1 DUF1689 PF07954.11 ETS82043.1 - 0.098 13.1 0.0 0.13 12.7 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1689) RTA1 PF04479.13 ETS82045.1 - 2.1e-40 138.6 7.8 2.1e-40 138.6 7.8 1.9 1 1 1 2 2 2 1 RTA1 like protein DUF3995 PF13160.6 ETS82045.1 - 0.0085 16.4 5.2 0.018 15.4 1.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3995) PMP1_2 PF08114.11 ETS82045.1 - 0.086 12.6 1.0 0.27 11.0 1.0 1.8 1 0 0 1 1 1 0 ATPase proteolipid family Polysacc_synt_C PF14667.6 ETS82045.1 - 2.4 8.2 10.0 0.16 12.0 2.2 2.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Fungal_trans_2 PF11951.8 ETS82046.1 - 2.6e-23 82.5 0.1 4.1e-23 81.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS82046.1 - 0.004 17.2 7.8 0.0071 16.4 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.15 ETS82047.1 - 2.7e-07 30.6 18.6 5.3e-07 29.6 18.6 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ETS82047.1 - 9.9e-06 25.6 20.0 9.9e-06 25.6 20.0 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 ETS82047.1 - 0.019 15.5 13.1 0.038 14.5 13.1 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor eIF3_subunit PF08597.10 ETS82047.1 - 0.027 14.4 9.0 0.043 13.7 9.0 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF3450 PF11932.8 ETS82047.1 - 0.038 13.3 4.7 0.06 12.7 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) NYD-SP28_assoc PF14775.6 ETS82047.1 - 0.068 13.3 2.6 0.17 12.0 2.6 1.7 1 0 0 1 1 1 0 Sperm tail C-terminal domain FAD_binding_3 PF01494.19 ETS82047.1 - 0.28 10.4 2.4 0.42 9.8 2.4 1.1 1 0 0 1 1 1 0 FAD binding domain SprA-related PF12118.8 ETS82047.1 - 0.49 9.5 8.7 0.9 8.6 8.7 1.4 1 0 0 1 1 1 0 SprA-related family Gcd10p PF04189.13 ETS82047.1 - 0.69 9.0 5.2 1 8.4 5.2 1.3 1 0 0 1 1 1 0 Gcd10p family DivIC PF04977.15 ETS82047.1 - 1.8 8.4 5.2 3.5 7.5 5.2 1.5 1 0 0 1 1 1 0 Septum formation initiator CDC45 PF02724.14 ETS82047.1 - 1.9 6.7 8.8 2.6 6.2 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.6 ETS82047.1 - 6.3 6.1 6.0 8.9 5.6 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.14 ETS82048.1 - 0.041 12.2 2.0 0.04 12.2 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 ETS82048.1 - 0.5 9.1 5.6 0.48 9.2 5.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF913 PF06025.12 ETS82048.1 - 1.7 7.6 3.9 1.8 7.4 3.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 ETS82048.1 - 3.4 6.4 7.0 4.3 6.0 7.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4614 PF15391.6 ETS82048.1 - 4.1 7.4 15.4 6.5 6.7 15.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Presenilin PF01080.17 ETS82048.1 - 4.6 5.9 5.2 5.8 5.6 5.2 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 ETS82048.1 - 6.3 5.2 6.1 6.9 5.1 6.1 1.0 1 0 0 1 1 1 0 Macoilin family Nop14 PF04147.12 ETS82048.1 - 7.2 4.7 12.5 8.8 4.4 12.5 1.0 1 0 0 1 1 1 0 Nop14-like family Filament PF00038.21 ETS82049.1 - 0.0022 17.7 13.2 0.0065 16.1 13.2 1.6 1 1 0 1 1 1 1 Intermediate filament protein Spc7 PF08317.11 ETS82049.1 - 0.0081 15.1 21.5 0.15 10.9 4.0 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein Atg14 PF10186.9 ETS82049.1 - 0.0082 15.3 16.7 0.016 14.3 12.2 2.2 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4201 PF13870.6 ETS82049.1 - 0.0085 15.8 14.2 0.37 10.5 7.9 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) DUF4407 PF14362.6 ETS82049.1 - 0.014 14.8 12.3 0.033 13.5 12.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.6 ETS82049.1 - 0.048 13.6 8.1 0.13 12.2 6.5 2.4 2 0 0 2 2 2 0 FlxA-like protein DUF948 PF06103.11 ETS82049.1 - 0.062 13.6 2.5 0.42 10.9 0.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PAXX PF15384.6 ETS82049.1 - 0.066 12.9 8.3 0.11 12.1 0.4 2.4 1 1 0 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 BLOC1_2 PF10046.9 ETS82049.1 - 0.07 13.4 0.9 0.07 13.4 0.9 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ER-remodelling PF14755.6 ETS82049.1 - 0.077 13.3 4.0 0.13 12.6 0.3 2.5 3 0 0 3 3 2 0 Intracellular membrane remodeller NPV_P10 PF05531.12 ETS82049.1 - 0.089 13.3 2.2 6.4 7.3 0.9 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein OmpH PF03938.14 ETS82049.1 - 0.21 11.9 19.0 0.37 11.1 0.4 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Spc24 PF08286.11 ETS82049.1 - 0.21 11.8 9.7 0.2 11.9 2.5 2.7 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Baculo_PEP_C PF04513.12 ETS82049.1 - 0.22 11.6 1.3 1.2 9.2 0.2 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 ETS82049.1 - 0.25 10.9 4.9 3.8 7.0 0.2 2.3 2 0 0 2 2 2 0 fzo-like conserved region Foamy_virus_ENV PF03408.14 ETS82049.1 - 0.26 9.1 0.1 0.37 8.6 0.1 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein SASP PF00269.20 ETS82049.1 - 0.3 11.2 2.8 4.5 7.4 0.2 2.6 2 0 0 2 2 2 0 Small, acid-soluble spore proteins, alpha/beta type IFT57 PF10498.9 ETS82049.1 - 0.36 9.7 9.0 0.55 9.1 9.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 HIP1_clath_bdg PF16515.5 ETS82049.1 - 0.39 11.4 17.6 1.6 9.4 8.4 2.6 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ADIP PF11559.8 ETS82049.1 - 0.47 10.5 18.1 0.51 10.4 9.9 2.4 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Phage_GP20 PF06810.11 ETS82049.1 - 0.5 10.2 15.1 0.58 9.9 5.7 2.9 3 1 0 3 3 2 0 Phage minor structural protein GP20 VPS38 PF17649.1 ETS82049.1 - 0.56 9.0 3.3 0.89 8.4 3.3 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 38 Fez1 PF06818.15 ETS82049.1 - 0.64 10.4 18.2 2.7 8.4 18.1 1.9 1 1 1 2 2 2 0 Fez1 IFT20 PF14931.6 ETS82049.1 - 0.65 10.2 14.5 0.055 13.6 5.5 2.8 2 1 1 3 3 2 0 Intraflagellar transport complex B, subunit 20 Tup_N PF08581.10 ETS82049.1 - 0.71 10.2 7.4 0.67 10.3 1.9 3.2 1 1 2 3 3 3 0 Tup N-terminal Exonuc_VII_L PF02601.15 ETS82049.1 - 0.79 9.2 11.0 2 7.9 11.0 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 ETS82049.1 - 0.84 7.5 4.0 1.1 7.2 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.12 ETS82049.1 - 0.88 10.2 13.1 0.91 10.2 4.1 3.4 2 1 0 2 2 2 0 SlyX Bacillus_HBL PF05791.11 ETS82049.1 - 1.1 9.0 4.0 1.4 8.7 1.5 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) YlqD PF11068.8 ETS82049.1 - 1.3 9.4 11.0 0.29 11.5 4.4 2.3 2 0 0 2 2 2 0 YlqD protein Golgin_A5 PF09787.9 ETS82049.1 - 1.7 8.0 14.5 2.4 7.5 14.5 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 HAUS-augmin3 PF14932.6 ETS82049.1 - 1.9 8.0 19.5 0.93 9.0 3.1 2.2 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF641 PF04859.12 ETS82049.1 - 2 8.8 10.6 13 6.1 6.1 2.7 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) TSC22 PF01166.18 ETS82049.1 - 3.6 8.0 9.5 0.29 11.5 0.4 3.3 2 1 1 3 3 3 0 TSC-22/dip/bun family Fmp27_WPPW PF10359.9 ETS82049.1 - 4 6.2 8.2 7.8 5.2 8.0 1.5 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DHR10 PF18595.1 ETS82049.1 - 4.5 7.4 25.5 10 6.2 16.1 3.0 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Sec2p PF06428.11 ETS82049.1 - 4.6 7.3 15.1 1 9.4 9.6 2.5 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p FlaC_arch PF05377.11 ETS82049.1 - 4.9 7.6 8.5 31 5.0 0.2 3.5 1 1 2 4 4 4 0 Flagella accessory protein C (FlaC) YabA PF06156.13 ETS82049.1 - 5.6 7.7 14.4 6.6 7.4 5.0 3.1 1 1 2 3 3 3 0 Initiation control protein YabA FapA PF03961.13 ETS82049.1 - 5.8 5.4 11.0 15 4.1 11.1 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A PRKG1_interact PF15898.5 ETS82049.1 - 6.8 7.7 19.7 0.48 11.4 8.6 2.5 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain AAA_13 PF13166.6 ETS82049.1 - 6.9 5.2 13.9 33 2.9 13.8 1.7 1 1 0 1 1 1 0 AAA domain 3A PF00803.18 ETS82051.1 - 0.076 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 3A/RNA2 movement protein family Cupin_2 PF07883.11 ETS82052.1 - 2.5e-06 27.1 0.1 4.4e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ETS82052.1 - 0.00017 21.2 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 ETS82052.1 - 0.024 14.6 0.1 0.029 14.3 0.1 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_6 PF12852.7 ETS82052.1 - 0.036 13.8 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 Cupin ARD PF03079.14 ETS82052.1 - 0.15 12.2 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family cobW PF02492.19 ETS82053.1 - 8.2e-48 162.3 5.1 7.5e-35 120.1 0.4 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 ETS82053.1 - 1.1e-20 73.4 0.4 8.7e-16 57.6 0.1 2.9 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 ETS82053.1 - 0.012 15.5 0.1 5.9 6.8 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 ETS82053.1 - 0.012 14.6 1.5 1.6 7.6 0.2 2.5 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 ETS82053.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 ETS82053.1 - 0.027 14.5 0.0 0.083 12.9 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 ETS82053.1 - 0.041 14.3 2.7 0.16 12.3 0.9 2.8 2 1 0 2 2 2 0 AAA ATPase domain Peptidase_A25 PF03418.14 ETS82053.1 - 0.065 12.1 0.7 0.2 10.5 0.3 1.8 1 1 0 2 2 2 0 Germination protease DUF615 PF04751.14 ETS82053.1 - 0.096 12.7 0.9 0.2 11.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF615) GTP_EFTU PF00009.27 ETS82053.1 - 0.34 10.4 4.2 12 5.4 1.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain SNARE PF05739.19 ETS82056.1 - 8e-14 51.4 0.2 1.7e-13 50.3 0.2 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 ETS82056.1 - 1e-08 34.1 1.1 2.2e-08 33.1 0.2 2.1 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 ETS82056.1 - 0.00026 20.7 9.9 0.0004 20.1 0.4 3.4 2 1 1 3 3 3 1 Syntaxin SOAR PF16533.5 ETS82056.1 - 0.012 15.5 0.2 0.012 15.5 0.2 2.0 2 0 0 2 2 2 0 STIM1 Orai1-activating region KxDL PF10241.9 ETS82056.1 - 0.014 15.6 5.9 0.18 12.1 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized conserved protein Prominin PF05478.11 ETS82056.1 - 0.015 13.3 4.4 0.092 10.7 0.1 2.2 2 0 0 2 2 2 0 Prominin Syntaxin-18_N PF10496.9 ETS82056.1 - 0.036 14.3 0.6 0.12 12.6 0.1 2.1 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF3158 PF11358.8 ETS82056.1 - 0.099 12.4 1.3 0.13 12.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3158) TRPM_tetra PF16519.5 ETS82056.1 - 0.1 12.7 3.3 0.44 10.7 0.2 3.4 4 0 0 4 4 4 0 Tetramerisation domain of TRPM MCPsignal PF00015.21 ETS82056.1 - 0.12 12.2 10.0 0.14 12.0 1.8 2.6 3 0 0 3 3 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FAM76 PF16046.5 ETS82056.1 - 0.18 11.1 4.7 0.26 10.6 0.1 2.0 1 1 1 2 2 2 0 FAM76 protein SF-assemblin PF06705.11 ETS82056.1 - 0.2 11.0 10.8 0.086 12.2 0.6 2.6 3 0 0 3 3 3 0 SF-assemblin/beta giardin DUF948 PF06103.11 ETS82056.1 - 0.3 11.4 6.3 2.4 8.4 0.1 3.4 4 1 0 4 4 3 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 ETS82056.1 - 0.34 10.9 7.9 3.5 7.7 0.1 3.6 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C4H2 PF10146.9 ETS82056.1 - 0.57 10.5 3.6 11 6.2 0.4 2.3 1 1 1 2 2 2 0 Zinc finger-containing protein BLOC1_2 PF10046.9 ETS82056.1 - 1.4 9.3 7.0 1.7 9.0 0.3 3.5 4 1 1 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 ETS82056.1 - 2.6 8.5 5.6 4.2 7.8 0.7 3.4 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) LPP PF04728.13 ETS82056.1 - 2.8 8.4 7.3 24 5.4 0.1 3.4 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Snapin_Pallidin PF14712.6 ETS82056.1 - 3.1 8.3 6.8 1.3 9.5 0.1 3.1 3 1 0 3 3 2 0 Snapin/Pallidin SlyX PF04102.12 ETS82056.1 - 4.3 8.0 11.7 0.15 12.7 0.7 3.4 3 1 0 3 3 3 0 SlyX DUF16 PF01519.16 ETS82056.1 - 4.4 7.9 13.4 0.14 12.6 1.2 2.7 3 0 0 3 3 3 0 Protein of unknown function DUF16 Jnk-SapK_ap_N PF09744.9 ETS82056.1 - 6.8 6.9 9.4 2.2 8.5 0.3 2.7 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Aldo_ket_red PF00248.21 ETS82057.1 - 1.2e-39 136.3 0.0 1.5e-37 129.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SET PF00856.28 ETS82058.1 - 7.8e-12 45.9 1.3 3.9e-11 43.6 1.3 2.3 1 1 0 1 1 1 1 SET domain Inhibitor_I36 PF03995.13 ETS82058.1 - 0.1 12.6 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Peptidase inhibitor family I36 ADH_N PF08240.12 ETS82059.1 - 6.9e-29 99.9 0.4 6.9e-29 99.9 0.4 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS82059.1 - 8.2e-16 58.2 0.6 1.6e-15 57.3 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS82059.1 - 5.1e-08 32.6 0.5 0.00049 19.7 0.0 2.4 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus FAD_binding_2 PF00890.24 ETS82059.1 - 0.00017 20.8 0.5 0.00026 20.2 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 ETS82059.1 - 0.007 15.7 1.6 0.007 15.7 1.6 1.7 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ETS82059.1 - 0.008 14.9 1.1 0.013 14.3 1.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 ETS82059.1 - 0.011 15.0 0.5 0.19 10.9 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase YdfZ PF14001.6 ETS82059.1 - 0.012 16.0 0.1 0.14 12.6 0.0 2.5 2 0 0 2 2 2 0 YdfZ protein Pyr_redox_3 PF13738.6 ETS82059.1 - 0.053 12.8 0.6 0.17 11.1 0.7 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS82059.1 - 0.06 13.6 1.4 0.18 12.1 0.8 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ETS82059.1 - 0.067 12.3 1.3 0.089 11.9 1.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 ETS82059.1 - 0.074 12.4 0.1 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 ETS82059.1 - 0.074 13.1 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.20 ETS82059.1 - 0.28 11.2 1.1 1.3 9.1 0.2 2.2 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 ETS82059.1 - 0.3 10.4 3.6 0.47 9.7 3.6 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS82059.1 - 3.2 8.4 5.3 3.4 8.3 0.4 2.7 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 ETS82060.1 - 6.1e-57 192.9 0.0 7.7e-57 192.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS82060.1 - 1.3e-50 171.6 0.1 1.9e-50 171.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS82060.1 - 4.4e-14 52.8 0.8 1.7e-13 50.9 0.8 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS82060.1 - 4.8e-08 32.8 0.0 6.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ETS82060.1 - 0.0028 16.8 0.2 0.019 14.1 0.1 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 ETS82060.1 - 0.072 13.0 0.8 0.13 12.1 0.3 1.6 2 0 0 2 2 2 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ETS82060.1 - 0.079 12.3 0.1 0.14 11.5 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase S-methyl_trans PF02574.16 ETS82060.1 - 0.091 12.6 0.1 2.3 8.0 0.1 2.0 2 0 0 2 2 2 0 Homocysteine S-methyltransferase NmrA PF05368.13 ETS82060.1 - 0.37 10.3 2.9 0.74 9.3 1.3 2.2 2 1 1 3 3 3 0 NmrA-like family AbrB_C PF18277.1 ETS82061.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 AbrB C-terminal domain Acetyltransf_1 PF00583.25 ETS82062.1 - 7.3e-11 42.3 0.0 9.3e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS82062.1 - 2.6e-08 34.2 0.1 3.8e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS82062.1 - 3.5e-07 30.2 0.1 5e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Rubredoxin_C PF18267.1 ETS82062.1 - 0.12 12.3 0.2 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin NAD+ reductase C-terminal domain Lipase_3 PF01764.25 ETS82063.1 - 4.7e-16 58.9 0.0 1.2e-14 54.4 0.0 2.5 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ETS82063.1 - 0.0005 20.7 0.3 0.0022 18.6 0.7 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS82063.1 - 0.03 13.6 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Hid1 PF12722.7 ETS82063.1 - 9.1 4.3 7.5 15 3.5 7.5 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glyco_hydro_43 PF04616.14 ETS82064.1 - 8.6e-27 94.2 2.8 2.2e-25 89.6 2.8 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Mid2 PF04478.12 ETS82066.1 - 0.00028 20.8 0.1 0.00043 20.1 0.1 1.4 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM65 PF10507.9 ETS82066.1 - 0.033 14.1 0.7 0.059 13.3 0.3 1.5 1 1 0 1 1 1 0 Transmembrane protein 65 7tm_3 PF00003.22 ETS82066.1 - 0.09 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR PRIMA1 PF16101.5 ETS82066.1 - 0.09 12.8 6.9 0.48 10.5 0.0 3.1 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 Dioxygenase_C PF00775.21 ETS82067.1 - 1.9e-09 37.2 0.5 4.3e-09 36.1 0.5 1.6 1 1 0 1 1 1 1 Dioxygenase TauD PF02668.16 ETS82069.1 - 5.5e-44 151.0 0.2 8.2e-44 150.4 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DAG1 PF05454.11 ETS82069.1 - 0.22 10.8 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Mcp5_PH PF12814.7 ETS82070.1 - 3.1e-45 153.2 0.0 8.2e-45 151.9 0.0 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 ETS82070.1 - 1.6e-06 28.5 0.0 5e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 PH domain zf-CCCH PF00642.24 ETS82071.1 - 1.9e-08 34.0 2.5 3.7e-08 33.1 2.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 ETS82071.1 - 8.7e-07 28.7 5.3 1.5e-06 27.9 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS82071.1 - 9e-06 25.6 6.4 1.8e-05 24.7 6.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 ETS82071.1 - 2e-05 24.5 6.2 3.9e-05 23.6 6.2 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 ETS82071.1 - 2.5e-05 24.3 3.1 2.5e-05 24.3 3.1 1.8 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-C3HC4_2 PF13923.6 ETS82071.1 - 3.1e-05 23.7 8.1 5.6e-05 22.9 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ETS82071.1 - 4.4e-05 23.3 9.1 7.8e-05 22.5 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 ETS82071.1 - 0.00011 21.9 2.6 0.00021 21.0 2.6 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-RING_5 PF14634.6 ETS82071.1 - 0.00012 22.0 8.0 0.00021 21.2 8.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 ETS82071.1 - 0.00025 21.3 7.1 0.00045 20.5 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_2 PF14608.6 ETS82071.1 - 0.092 13.2 3.6 0.19 12.2 3.6 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-C3HC4_4 PF15227.6 ETS82071.1 - 0.097 12.8 7.7 0.23 11.7 7.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ETS82071.1 - 0.12 12.3 5.2 0.22 11.4 5.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 GMC_oxred_N PF00732.19 ETS82072.1 - 1.9e-52 178.5 0.0 2.9e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS82072.1 - 3.6e-37 128.1 0.0 6e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS82072.1 - 1.9e-06 27.2 0.0 0.023 13.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS82072.1 - 3.6e-05 23.9 0.1 0.00019 21.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ETS82072.1 - 6.4e-05 22.2 0.0 9.4e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 ETS82072.1 - 0.00018 21.2 0.2 0.0037 16.9 0.1 2.8 3 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS82072.1 - 0.00099 18.4 0.0 0.0078 15.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ETS82072.1 - 0.0083 15.0 0.0 0.017 14.0 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 ETS82072.1 - 0.12 11.6 0.0 0.36 10.0 0.0 1.8 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 ETS82072.1 - 0.13 12.9 0.1 0.96 10.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldedh PF00171.22 ETS82073.1 - 1.8e-159 531.1 0.1 2.1e-159 530.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 ETS82073.1 - 0.05 13.5 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 WTAP/Mum2p family PYNP_C PF07831.13 ETS82073.1 - 0.15 11.8 0.0 0.48 10.1 0.0 1.9 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain Cellulase PF00150.18 ETS82074.1 - 8.3e-16 58.2 0.0 8.2e-10 38.6 0.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 ETS82074.1 - 1.1e-06 29.0 0.0 2.3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 ETS82074.1 - 0.11 12.0 0.2 0.22 11.1 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolases family 35 UbiA PF01040.18 ETS82075.1 - 1.6e-14 53.8 12.5 1.6e-14 53.8 12.5 2.0 1 1 0 2 2 2 2 UbiA prenyltransferase family SNF2_N PF00176.23 ETS82076.1 - 1.4e-59 201.6 0.8 2.2e-59 201.0 0.8 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS82076.1 - 1.1e-14 54.7 0.0 2.6e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS82076.1 - 5e-14 52.7 0.1 1.4e-13 51.3 0.1 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-MYND PF01753.18 ETS82076.1 - 2.4e-06 27.5 32.8 0.00068 19.7 8.4 3.1 3 0 0 3 3 3 2 MYND finger zf-RING_UBOX PF13445.6 ETS82076.1 - 9.3e-05 22.4 2.1 0.0016 18.4 3.7 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ETS82076.1 - 0.0002 21.2 2.8 0.0002 21.2 2.8 3.3 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ETS82076.1 - 0.0002 21.1 3.7 0.0002 21.1 3.7 2.3 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 ETS82076.1 - 0.0008 19.2 2.6 0.0008 19.2 2.6 2.2 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ETS82076.1 - 0.00086 19.1 4.3 0.0031 17.3 4.3 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ETS82076.1 - 0.0092 16.3 2.5 0.0092 16.3 2.5 3.3 3 0 0 3 3 1 1 Ring finger domain zf-RING_6 PF14835.6 ETS82076.1 - 6.2 6.8 10.3 0.046 13.6 0.9 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein YrhC PF14143.6 ETS82077.1 - 0.77 9.9 2.9 1.2 9.3 0.2 2.4 2 0 0 2 2 2 0 YrhC-like protein NAD_binding_8 PF13450.6 ETS82078.1 - 2.9e-12 46.6 0.2 6.6e-12 45.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ETS82078.1 - 1.6e-06 27.7 0.0 3.6e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 ETS82078.1 - 3.2e-06 26.8 0.1 2.8e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS82078.1 - 7.9e-06 25.2 0.8 1.3e-05 24.4 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS82078.1 - 1.7e-05 24.6 1.5 4.4e-05 23.2 1.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS82078.1 - 0.00016 20.6 0.3 0.00024 19.9 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 ETS82078.1 - 0.00019 20.8 0.4 0.002 17.4 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS82078.1 - 0.00032 20.0 0.5 0.00052 19.3 0.5 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 ETS82078.1 - 0.00069 19.0 0.5 0.0071 15.6 0.3 2.2 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 ETS82078.1 - 0.0071 15.6 0.2 0.014 14.7 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS82078.1 - 0.012 16.2 1.1 0.022 15.3 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ETS82078.1 - 0.021 15.1 0.1 0.055 13.7 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain K_oxygenase PF13434.6 ETS82078.1 - 0.022 13.9 0.7 0.99 8.5 0.3 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 ETS82078.1 - 0.027 13.5 0.1 0.045 12.8 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 ETS82078.1 - 0.25 11.3 0.7 0.61 10.1 0.2 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding UQ_con PF00179.26 ETS82079.1 - 1.1e-48 164.4 0.0 1.3e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ETS82079.1 - 0.0018 18.0 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ETS82079.1 - 0.25 11.6 0.9 0.37 11.1 0.9 1.5 1 1 0 1 1 1 0 RWD domain Asn_synthase PF00733.21 ETS82080.1 - 6.4e-94 315.5 0.1 1.5e-53 182.7 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 ETS82080.1 - 2.7e-37 127.4 0.0 4.2e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ETS82080.1 - 4.1e-28 98.2 0.0 7e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 ETS82080.1 - 1.2e-07 31.4 0.0 2.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 ETS82080.1 - 0.00035 19.8 0.1 0.0016 17.6 0.1 1.9 1 1 0 1 1 1 1 NAD synthase QueC PF06508.13 ETS82080.1 - 0.046 13.2 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Porin_3 PF01459.22 ETS82081.1 - 4.3e-66 223.1 11.8 1.1e-54 185.7 4.1 2.0 2 0 0 2 2 2 2 Eukaryotic porin DnaJ PF00226.31 ETS82082.1 - 7.6e-20 70.8 0.2 1.3e-19 70.1 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3488 PF11992.8 ETS82083.1 - 0.44 9.5 4.7 0.61 9.0 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Peptidase_M48 PF01435.18 ETS82086.1 - 1.4e-38 132.6 0.0 2e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Cyt-b5 PF00173.28 ETS82087.1 - 2.6e-20 72.3 0.4 2.9e-20 72.2 0.4 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RE_NgoFVII PF09565.10 ETS82087.1 - 0.067 12.5 0.1 0.086 12.1 0.1 1.1 1 0 0 1 1 1 0 NgoFVII restriction endonuclease V-ATPase_H_C PF11698.8 ETS82087.1 - 0.071 13.2 0.0 0.18 11.9 0.0 1.7 1 1 1 2 2 2 0 V-ATPase subunit H dCMP_cyt_deam_1 PF00383.23 ETS82088.1 - 8.5e-26 89.8 1.1 1.6e-25 88.9 1.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ETS82088.1 - 1.6e-09 37.7 0.1 2.9e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 ETS82088.1 - 1.9e-05 25.2 0.0 5.8e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ETS82088.1 - 0.0011 19.2 0.2 0.0031 17.7 0.2 1.8 1 1 0 1 1 1 1 AAA domain CtnDOT_TraJ PF07863.11 ETS82088.1 - 0.13 12.9 1.6 0.31 11.7 0.1 2.3 3 0 0 3 3 3 0 Homologues of TraJ from Bacteroides conjugative transposon 2-oxogl_dehyd_N PF16078.5 ETS82088.1 - 0.15 11.7 0.2 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus AAA_28 PF13521.6 ETS82088.1 - 0.2 11.9 0.3 0.51 10.6 0.1 1.8 2 1 0 2 2 2 0 AAA domain ATG7_N PF16420.5 ETS82089.1 - 1.4e-103 346.6 0.0 1.8e-103 346.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 ETS82089.1 - 2.1e-44 151.7 0.0 3.3e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family AMP-binding PF00501.28 ETS82089.1 - 0.16 10.5 0.2 0.33 9.5 0.2 1.4 1 1 0 1 1 1 0 AMP-binding enzyme MFS_1 PF07690.16 ETS82090.1 - 4e-29 101.6 31.7 4e-29 101.6 31.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS82090.1 - 1.9e-20 73.2 17.2 3.3e-17 62.5 3.0 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter LpoB PF13036.6 ETS82090.1 - 0.2 11.6 0.2 0.31 11.0 0.2 1.2 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB DnaJ PF00226.31 ETS82091.1 - 8.3e-12 45.1 0.0 1.3e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain CRISPR_Cse2 PF09485.10 ETS82091.1 - 0.061 13.9 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) RelA_SpoT PF04607.17 ETS82092.1 - 2.3e-05 24.7 0.1 7.2e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Region found in RelA / SpoT proteins Abhydrolase_3 PF07859.13 ETS82093.1 - 1.2e-25 90.6 0.0 1.6e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS82093.1 - 1.9e-12 46.8 0.0 1.3e-11 44.0 0.0 2.1 1 1 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 ETS82093.1 - 0.016 14.1 0.0 0.066 12.1 0.0 1.9 1 1 0 1 1 1 0 Carboxylesterase family YrhK PF14145.6 ETS82094.1 - 0.035 14.0 1.3 0.18 11.7 0.0 2.5 2 1 0 2 2 2 0 YrhK-like protein Saf_2TM PF18303.1 ETS82094.1 - 5.6 6.5 8.3 3 7.4 0.1 3.4 3 1 1 4 4 4 0 SAVED-fused 2TM effector domain Hydantoinase_B PF02538.14 ETS82095.1 - 2.4e-190 633.3 0.0 3.2e-190 632.9 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 ETS82095.1 - 2.4e-90 302.7 0.0 6.3e-90 301.4 0.0 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ETS82095.1 - 4.5e-56 189.4 0.4 6.2e-54 182.4 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Pox_P4B PF03292.14 ETS82095.1 - 0.17 10.2 0.0 0.36 9.0 0.0 1.4 2 0 0 2 2 2 0 Poxvirus P4B major core protein Abhydrolase_1 PF00561.20 ETS82096.1 - 1.1e-27 97.3 0.2 3.7e-27 95.6 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS82096.1 - 2.3e-22 79.5 0.6 3e-21 75.8 0.6 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS82096.1 - 3.5e-16 60.5 0.0 5.1e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ETS82096.1 - 3.2e-07 30.1 0.3 0.012 15.1 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 ETS82096.1 - 0.00049 20.2 0.0 0.0011 19.1 0.0 1.6 2 0 0 2 2 2 1 TAP-like protein Ndr PF03096.14 ETS82096.1 - 0.00051 18.8 0.0 0.00072 18.3 0.0 1.4 1 1 0 1 1 1 1 Ndr family FSH1 PF03959.13 ETS82096.1 - 0.00098 18.8 0.1 0.0021 17.8 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase (FSH1) AXE1 PF05448.12 ETS82096.1 - 0.0018 17.0 0.8 0.22 10.1 0.0 2.5 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 ETS82096.1 - 0.023 14.6 0.0 0.13 12.1 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 ETS82096.1 - 0.05 13.3 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein MFS_1 PF07690.16 ETS82097.1 - 1.1e-33 116.6 26.1 2.3e-33 115.6 24.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Cu-oxidase_3 PF07732.15 ETS82098.1 - 1.7e-40 137.7 3.3 6e-38 129.5 1.0 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ETS82098.1 - 8.9e-40 135.6 2.5 3.2e-34 117.6 0.0 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 ETS82098.1 - 4e-29 101.8 0.3 2.4e-21 76.5 0.2 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cupredoxin_1 PF13473.6 ETS82098.1 - 0.033 14.3 0.0 16 5.7 0.0 3.0 3 0 0 3 3 3 0 Cupredoxin-like domain SAT PF16073.5 ETS82099.1 - 1.6e-80 270.3 1.4 5.2e-80 268.6 0.2 2.2 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 ETS82099.1 - 3.2e-73 246.4 0.0 7e-73 245.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 ETS82099.1 - 5.3e-46 157.6 0.0 1.3e-45 156.3 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ETS82099.1 - 9e-35 119.2 0.4 3e-34 117.6 0.4 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 ETS82099.1 - 1.9e-22 80.5 0.1 1.7e-21 77.4 0.0 2.5 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 ETS82099.1 - 4.2e-22 78.3 2.7 3.5e-12 46.5 0.2 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 ETS82099.1 - 1.7e-14 53.8 0.0 3.6e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 ETS82099.1 - 0.00021 20.7 0.2 0.0013 18.2 0.1 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 ETS82099.1 - 0.00082 19.8 0.0 0.0028 18.1 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Hydrolase_4 PF12146.8 ETS82099.1 - 0.01 15.2 0.2 0.13 11.5 0.0 2.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 NYD-SP12_N PF15015.6 ETS82099.1 - 0.15 10.4 0.0 0.22 9.8 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Zn_clus PF00172.18 ETS82100.1 - 6.8e-08 32.5 5.6 6.8e-08 32.5 5.6 2.0 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 ETS82101.1 - 9.2e-54 182.5 0.1 1.7e-53 181.6 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS82101.1 - 2.8e-46 157.5 0.1 3.5e-46 157.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS82101.1 - 1.3e-12 48.0 0.3 1.8e-12 47.5 0.3 1.1 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 ETS82101.1 - 0.054 13.0 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family Zn_clus PF00172.18 ETS82102.1 - 4.2e-05 23.6 9.1 4.2e-05 23.6 9.1 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 ETS82103.1 - 3.8e-23 82.0 0.0 4e-21 75.4 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS82103.1 - 2.7e-11 43.5 0.0 3.2e-09 36.7 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS82103.1 - 6.9e-06 26.1 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS82103.1 - 0.0018 17.8 0.0 0.0061 16.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family MAP17 PF15807.5 ETS82103.1 - 0.009 16.2 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Polysacc_synt_2 PF02719.15 ETS82103.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HET PF06985.11 ETS82105.1 - 9.6e-26 90.9 0.0 2.3e-25 89.6 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CAMSAP_CH PF11971.8 ETS82105.1 - 0.17 11.7 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain Sugar_tr PF00083.24 ETS82106.1 - 6.3e-93 312.1 22.3 7.8e-93 311.8 22.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS82106.1 - 1.2e-16 60.6 38.6 4.9e-13 48.7 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ac110_PIF PF07280.11 ETS82106.1 - 0.018 14.8 0.1 0.056 13.2 0.1 1.9 1 0 0 1 1 1 0 Per os infectivity factor AC110 Kelch_4 PF13418.6 ETS82107.1 - 8.9e-24 83.3 7.1 4.7e-08 32.9 0.0 6.2 6 1 1 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.6 ETS82107.1 - 8.5e-23 80.1 12.5 6.9e-05 23.0 0.0 8.0 9 0 0 9 9 9 6 Galactose oxidase, central domain Kelch_6 PF13964.6 ETS82107.1 - 3.3e-20 71.6 0.4 3.2e-06 27.2 0.0 5.5 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 ETS82107.1 - 5.2e-17 61.2 4.3 2.4e-05 23.8 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 ETS82107.1 - 6.6e-16 57.9 0.3 0.00061 19.7 0.0 5.4 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 ETS82107.1 - 9.4e-13 47.6 1.7 2.6e-05 24.0 0.0 5.4 5 0 0 5 5 5 4 Kelch motif 2Fe-2S_thioredx PF01257.19 ETS82108.1 - 1.1e-58 197.2 0.1 1.4e-58 196.9 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DctP PF03480.13 ETS82108.1 - 0.13 11.5 0.0 0.62 9.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 AhpC-TSA PF00578.21 ETS82109.1 - 1.8e-22 79.5 0.0 3.1e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ETS82109.1 - 1.1e-12 47.9 0.0 1.6e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 ETS82109.1 - 0.0038 17.3 0.0 0.0098 16.0 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme BAR PF03114.18 ETS82110.1 - 9.5e-70 234.9 3.9 1.2e-69 234.6 3.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 ETS82110.1 - 6e-16 57.8 0.1 1e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ETS82110.1 - 1.9e-12 46.8 0.1 3.3e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ETS82110.1 - 1.3e-09 37.6 0.0 4.4e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.10 ETS82110.1 - 0.024 14.2 3.8 0.3 10.6 2.0 2.2 2 0 0 2 2 2 0 Vps5 C terminal like CT_C_D PF02682.16 ETS82110.1 - 0.032 14.0 0.1 0.063 13.0 0.1 1.4 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D BRE1 PF08647.11 ETS82110.1 - 8.1 6.6 13.9 7.5 6.7 0.2 2.7 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Aminotran_5 PF00266.19 ETS82111.1 - 4e-92 309.0 0.0 5.4e-92 308.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ETS82111.1 - 8.1e-07 28.6 0.1 1.3e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ETS82111.1 - 1.5e-06 27.8 0.0 4.8e-06 26.1 0.1 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 ETS82111.1 - 0.037 12.7 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 ETS82111.1 - 0.063 11.8 0.0 0.096 11.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme cNMP_binding PF00027.29 ETS82112.1 - 2.5e-40 136.4 0.0 8.4e-20 70.6 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 ETS82112.1 - 9e-07 28.5 0.2 1.7e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit BCAS2 PF05700.11 ETS82113.1 - 1.4e-64 217.6 6.8 1.7e-64 217.3 6.8 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.8 ETS82113.1 - 0.41 10.9 5.5 0.1 12.8 1.1 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Ceramidase_alk PF04734.13 ETS82114.1 - 4.9e-222 738.1 0.0 5.7e-222 737.8 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 ETS82114.1 - 2.5e-59 199.9 0.0 4.1e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal dCMP_cyt_deam_1 PF00383.23 ETS82115.1 - 5.7e-11 42.2 0.0 7.9e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ETS82115.1 - 6.5e-07 29.2 0.0 8.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 ETS82115.1 - 0.0043 17.2 0.3 0.007 16.5 0.3 1.2 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 ETS82115.1 - 0.044 13.7 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain DUF1450 PF07293.11 ETS82115.1 - 0.18 11.7 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1450) Cu-oxidase PF00394.22 ETS82116.1 - 6.2e-40 136.9 0.7 1.9e-39 135.3 0.1 2.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ETS82116.1 - 9.1e-40 135.6 10.7 2.7e-39 134.0 0.8 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ETS82116.1 - 2.9e-35 120.8 7.7 1e-34 119.1 3.7 3.5 3 1 0 3 3 3 1 Multicopper oxidase MFS_1 PF07690.16 ETS82117.1 - 6.6e-33 114.1 26.6 9.1e-33 113.6 26.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily AA_permease_2 PF13520.6 ETS82118.1 - 5.4e-59 200.1 49.4 6.6e-59 199.8 49.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS82118.1 - 2.6e-26 92.3 41.8 3.5e-26 91.8 41.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1736 PF08409.11 ETS82118.1 - 0.043 13.8 1.1 3.5 7.7 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1736) APG5 PF04106.12 ETS82119.1 - 2.4e-44 151.6 0.0 7.5e-44 150.0 0.0 1.7 1 1 0 1 1 1 1 Autophagy protein Apg5 Zn_clus PF00172.18 ETS82120.1 - 4.1e-09 36.4 13.3 6.8e-09 35.7 13.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 ETS82123.1 - 4e-23 81.3 21.5 5e-08 33.5 0.6 6.2 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS82123.1 - 8.7e-11 42.0 0.5 0.01 16.1 0.0 5.4 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ETS82123.1 - 5.6e-05 22.0 0.1 0.43 9.2 0.0 3.3 4 0 0 4 4 4 3 Nucleoporin Nup120/160 MBD_C PF14048.6 ETS82124.1 - 0.041 14.6 1.7 0.54 11.0 0.3 4.0 2 0 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 Snf7 PF03357.21 ETS82126.1 - 9.8e-33 113.2 21.5 9.8e-33 113.2 21.5 2.0 1 1 1 2 2 2 1 Snf7 Peptidase_M9_N PF08453.10 ETS82126.1 - 0.013 15.3 1.2 0.022 14.5 1.2 1.4 1 0 0 1 1 1 0 Peptidase family M9 N-terminal Allexi_40kDa PF05549.11 ETS82126.1 - 0.067 12.7 7.4 0.098 12.2 7.3 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF3138 PF11336.8 ETS82126.1 - 0.49 9.0 11.3 0.58 8.7 7.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) zf-C4H2 PF10146.9 ETS82126.1 - 2.9 8.1 18.1 5.3 7.3 18.1 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein MFS_1 PF07690.16 ETS82127.1 - 5.9e-48 163.6 42.2 1.9e-42 145.4 29.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS82127.1 - 7e-06 24.9 12.9 7e-06 24.9 12.9 3.1 2 2 1 3 3 3 1 MFS/sugar transport protein OATP PF03137.20 ETS82127.1 - 0.0066 14.8 4.3 0.031 12.6 3.1 2.3 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF4525 PF15027.6 ETS82127.1 - 0.25 11.0 0.6 1.1 9.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) RRP7 PF12923.7 ETS82128.1 - 4.4e-29 101.0 13.2 4.4e-29 101.0 13.2 2.1 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 ETS82128.1 - 1.6e-16 60.5 0.0 3e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain Usp PF00582.26 ETS82128.1 - 0.2 12.2 4.9 0.58 10.7 0.4 2.4 2 0 0 2 2 2 0 Universal stress protein family Methyltransf_34 PF11312.8 ETS82129.1 - 1.5e-97 326.5 0.0 3.3e-97 325.4 0.0 1.5 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase dsrm PF00035.26 ETS82129.1 - 2.7 8.7 6.9 5.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Double-stranded RNA binding motif Syja_N PF02383.18 ETS82130.1 - 5.2e-96 321.7 0.0 7.5e-96 321.2 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 ETS82130.1 - 6.1e-43 145.2 0.0 1.2e-42 144.2 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase Ribosomal_L7Ae PF01248.26 ETS82131.1 - 3.5e-24 84.3 0.0 4.1e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 ETS82131.1 - 7e-05 22.9 0.1 8.7e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 ETS82131.1 - 0.00055 19.8 0.0 0.00082 19.2 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain ATP-synt_C PF00137.21 ETS82132.1 - 3.1e-34 117.1 35.9 7.5e-22 77.5 14.8 2.5 3 0 0 3 3 3 2 ATP synthase subunit C Pkinase PF00069.25 ETS82133.1 - 7e-06 25.6 0.0 4.9e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS82133.1 - 0.0029 16.9 0.0 0.0048 16.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ETS82134.1 - 0.049 13.0 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain TPR_12 PF13424.6 ETS82137.1 - 0.0059 16.9 3.3 0.0083 16.4 1.5 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 ETS82137.1 - 1.4 8.9 6.4 1.6 8.7 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Response_reg PF00072.24 ETS82138.1 - 5.9e-27 94.1 0.5 9.8e-27 93.3 0.5 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 ETS82138.1 - 3.3e-26 92.0 0.0 9.6e-20 71.2 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ETS82138.1 - 1e-14 54.3 0.0 2.4e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain dCache_1 PF02743.18 ETS82138.1 - 0.0014 18.5 1.5 0.0029 17.5 1.5 1.6 1 0 0 1 1 1 1 Cache domain HAMP PF00672.25 ETS82138.1 - 0.017 15.5 0.1 9.7 6.7 0.0 2.7 2 0 0 2 2 2 0 HAMP domain SPT16 PF08644.11 ETS82139.1 - 7.1e-55 185.3 0.1 7.1e-55 185.3 0.1 2.8 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 ETS82139.1 - 9.5e-55 184.8 0.1 9.5e-55 184.8 0.1 2.1 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 ETS82139.1 - 1.2e-23 83.9 0.0 2.1e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 ETS82139.1 - 1.6e-15 57.3 0.1 6.2e-15 55.4 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Chromo PF00385.24 ETS82140.1 - 2.5e-15 56.1 0.9 4.7e-15 55.2 0.9 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DDE_5 PF13546.6 ETS82140.1 - 1.3 8.2 7.0 0.73 9.1 0.2 2.9 3 0 0 3 3 3 0 DDE superfamily endonuclease DUF4661 PF15576.6 ETS82140.1 - 3.2 7.6 14.7 0.23 11.4 7.9 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4661) Hid1 PF12722.7 ETS82140.1 - 3.2 5.8 11.8 0.87 7.6 8.9 1.4 1 1 0 1 1 1 0 High-temperature-induced dauer-formation protein APC_basic PF05956.11 ETS82141.1 - 0.0018 17.8 5.9 0.0034 16.9 5.9 1.4 1 0 0 1 1 1 1 APC basic domain SUR7 PF06687.12 ETS82142.1 - 1.2e-22 80.7 12.0 1.2e-22 80.7 12.0 1.6 1 1 1 2 2 2 2 SUR7/PalI family Trp_oprn_chp PF09534.10 ETS82142.1 - 0.0084 15.9 1.1 0.013 15.3 1.1 1.4 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF973 PF06157.11 ETS82142.1 - 0.012 14.7 1.7 0.012 14.7 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF973) DUF4293 PF14126.6 ETS82142.1 - 0.37 11.0 5.0 0.88 9.8 3.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) ASFV_J13L PF05568.11 ETS82142.1 - 0.4 10.4 0.0 0.4 10.4 0.0 2.1 1 1 1 2 2 2 0 African swine fever virus J13L protein DUF5316 PF17247.2 ETS82142.1 - 2.6 8.1 7.2 0.86 9.7 0.3 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5316) EphA2_TM PF14575.6 ETS82142.1 - 6.1 7.8 0.0 6.1 7.8 0.0 2.7 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Ric8 PF10165.9 ETS82143.1 - 2.2e-123 412.7 0.1 2.6e-123 412.5 0.1 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn WAPL PF07814.13 ETS82143.1 - 0.017 14.0 0.5 0.034 12.9 0.5 1.5 1 1 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin NUC130_3NT PF08158.12 ETS82143.1 - 0.077 13.3 0.0 15 6.0 0.0 2.8 2 0 0 2 2 2 0 NUC130/3NT domain Rif1_N PF12231.8 ETS82144.1 - 2.2e-142 474.5 7.3 3.1e-142 474.0 7.3 1.2 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Cnd1_N PF12922.7 ETS82144.1 - 3.4 7.5 5.0 0.43 10.4 0.1 2.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term Aldose_epim PF01263.20 ETS82145.1 - 9.2e-42 143.4 0.0 1.1e-41 143.1 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DAHP_synth_2 PF01474.16 ETS82146.1 - 5.1e-203 674.4 0.0 5.8e-203 674.3 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family VPS28 PF03997.12 ETS82149.1 - 9.9e-68 227.5 0.1 1.2e-67 227.3 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein Noc2 PF03715.13 ETS82150.1 - 2.2e-129 431.0 0.0 4e-129 430.1 0.0 1.5 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 ETS82150.1 - 0.00022 19.7 0.1 0.00022 19.7 0.1 3.7 2 2 1 3 3 3 1 Nop14-like family Cwf_Cwc_15 PF04889.12 ETS82150.1 - 3.4 7.3 68.4 0.033 13.9 21.3 3.2 2 1 1 3 3 3 0 Cwf15/Cwc15 cell cycle control protein adh_short PF00106.25 ETS82152.1 - 7.6e-38 129.9 0.0 9.7e-38 129.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS82152.1 - 2e-32 112.6 0.0 2.6e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS82152.1 - 2e-12 47.4 0.0 2.9e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 ETS82152.1 - 0.071 12.9 0.6 0.15 11.9 0.3 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pro-kuma_activ PF09286.11 ETS82154.1 - 0.0049 17.2 1.2 0.015 15.6 0.2 1.9 1 1 0 2 2 2 1 Pro-kumamolisin, activation domain DUF373 PF04123.13 ETS82154.1 - 0.21 11.0 3.0 0.3 10.5 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Aldo_ket_red PF00248.21 ETS82155.1 - 1.5e-41 142.5 0.0 2.2e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.7 ETS82156.1 - 8.1e-34 115.1 21.8 6.3e-09 36.0 1.2 6.6 4 2 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ETS82156.1 - 3.8e-22 77.8 19.1 4.3e-07 29.6 2.0 5.2 3 2 1 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 ETS82156.1 - 1.9e-14 53.5 12.5 5.2e-07 29.3 3.9 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 ETS82156.1 - 2.1e-06 27.3 11.9 0.084 13.0 0.5 7.9 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 ETS82156.1 - 0.0026 18.1 19.3 8.5 7.4 0.2 8.1 8 0 0 8 8 8 2 Leucine Rich Repeat Glyco_hydro_79C PF16862.5 ETS82157.1 - 7.8e-19 68.5 0.1 2.1e-18 67.1 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Hydrolase_4 PF12146.8 ETS82158.1 - 4.2e-05 22.9 0.0 0.082 12.2 0.0 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS82158.1 - 0.00019 22.1 0.0 0.00053 20.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 ETS82158.1 - 0.0024 17.8 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 ETS82158.1 - 0.15 11.7 0.0 3.9 7.0 0.0 2.6 2 1 1 3 3 3 0 alpha/beta hydrolase fold NAD_binding_6 PF08030.12 ETS82160.1 - 1.7e-22 80.2 0.0 2.7e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ETS82160.1 - 2.6e-22 79.0 0.0 6e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 ETS82160.1 - 9.5e-20 71.0 11.1 9.5e-20 71.0 11.1 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 ETS82160.1 - 0.12 13.0 0.0 8.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Myosin_head PF00063.21 ETS82161.1 - 2.5e-239 796.0 6.8 3e-239 795.7 6.8 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 ETS82161.1 - 3.7e-50 170.2 0.0 6.6e-50 169.4 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 ETS82161.1 - 1.6e-12 46.8 0.2 3.1e-12 45.9 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ETS82161.1 - 4.6e-09 36.0 0.1 1e-08 34.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ETS82161.1 - 2.1e-07 30.5 0.0 5.1e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain GCFC PF07842.12 ETS82161.1 - 0.0046 16.6 0.0 0.012 15.2 0.0 1.6 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein SH3_3 PF08239.11 ETS82161.1 - 0.0048 17.1 0.3 0.016 15.4 0.3 2.0 1 0 0 1 1 1 1 Bacterial SH3 domain IQ PF00612.27 ETS82161.1 - 0.0098 15.6 8.4 0.17 11.8 2.4 2.7 1 1 1 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.6 ETS82161.1 - 0.046 14.0 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 ETS82161.1 - 0.05 13.1 0.3 6.3 6.3 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 ETS82161.1 - 0.073 13.4 0.0 0.28 11.5 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 ETS82161.1 - 0.1 12.5 0.1 0.31 10.9 0.1 1.8 1 0 0 1 1 1 0 NACHT domain hSH3 PF14603.6 ETS82161.1 - 0.15 12.5 0.0 0.69 10.4 0.0 2.1 1 0 0 1 1 1 0 Helically-extended SH3 domain DHHC PF01529.20 ETS82162.1 - 6e-32 110.6 2.4 1.1e-31 109.7 2.4 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase OmpH PF03938.14 ETS82162.1 - 0.064 13.6 0.1 0.097 13.0 0.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RRM_1 PF00076.22 ETS82163.1 - 5.8e-14 51.7 0.0 8.8e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ETS82163.1 - 0.082 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif MFS_1 PF07690.16 ETS82164.1 - 1.1e-22 80.5 33.0 3.2e-14 52.6 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS82164.1 - 4.9e-13 48.7 17.9 9.5e-13 47.8 17.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter CE2_N PF17996.1 ETS82165.1 - 3.7e-20 71.9 0.0 8.9e-20 70.7 0.0 1.7 2 0 0 2 2 2 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL_2 PF13472.6 ETS82165.1 - 1.3e-15 58.3 1.7 1.3e-15 58.3 1.7 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family CBM_1 PF00734.18 ETS82165.1 - 6.2e-12 45.3 9.1 1.3e-11 44.3 9.1 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.22 ETS82165.1 - 9.7e-06 25.7 0.0 2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4397 PF14344.6 ETS82165.1 - 0.002 18.9 5.3 0.026 15.3 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4397) MFS_1 PF07690.16 ETS82166.1 - 4.9e-13 48.7 88.6 1.8e-11 43.6 50.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily APG6 PF04111.12 ETS82167.1 - 3.4e-67 225.9 0.0 5.4e-67 225.2 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 ETS82167.1 - 2.7e-36 125.1 15.2 4.1e-36 124.4 15.2 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF3450 PF11932.8 ETS82167.1 - 0.076 12.3 7.8 1.9 7.7 9.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Sec34 PF04136.15 ETS82167.1 - 0.32 10.9 5.1 0.63 9.9 5.1 1.4 1 0 0 1 1 1 0 Sec34-like family FUSC PF04632.12 ETS82167.1 - 1 7.8 1.8 1.4 7.3 1.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0242 PF06785.11 ETS82167.1 - 2.5 8.2 12.3 4.8 7.2 12.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 ETS82167.1 - 2.8 5.8 4.9 3.8 5.3 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 ETS82167.1 - 3.1 8.5 5.4 0.6 10.8 1.7 1.7 2 0 0 2 2 2 0 Initiation control protein YabA Scm3 PF10384.9 ETS82168.1 - 1e-22 79.6 2.7 9.8e-22 76.5 0.4 3.1 3 0 0 3 3 3 1 Centromere protein Scm3 Pkinase PF00069.25 ETS82169.1 - 1.2e-64 218.3 0.2 1.4e-64 218.0 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS82169.1 - 5e-19 68.6 0.0 7.1e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ETS82169.1 - 1.3e-07 31.8 0.0 4.6e-06 26.7 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ETS82169.1 - 0.0048 16.2 0.0 0.0065 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ETS82169.1 - 0.0071 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ETS82169.1 - 0.018 14.4 0.3 0.032 13.6 0.3 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 ETS82169.1 - 0.082 12.5 0.2 0.082 12.5 0.2 2.0 3 0 0 3 3 3 0 Choline/ethanolamine kinase DUF3807 PF12720.7 ETS82170.1 - 3.8e-53 180.5 8.4 4.7e-53 180.2 8.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Coilin_N PF15862.5 ETS82170.1 - 0.048 13.5 4.0 0.071 12.9 4.0 1.4 1 0 0 1 1 1 0 Coilin N-terminus TMEM214 PF10151.9 ETS82170.1 - 0.27 9.7 1.7 0.32 9.4 1.7 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF908 PF06012.12 ETS82171.1 - 0.48 9.8 7.2 0.68 9.3 7.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF4554 PF15091.6 ETS82171.1 - 2.9 6.7 5.8 0.53 9.1 2.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4554) Atg14 PF10186.9 ETS82172.1 - 1.8e-71 240.9 0.0 2.5e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 ETS82172.1 - 0.03 13.7 7.2 0.044 13.1 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS6_N PF14661.6 ETS82172.1 - 0.11 12.1 5.9 0.19 11.3 5.9 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus OmpH PF03938.14 ETS82172.1 - 0.58 10.5 7.8 0.95 9.8 7.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Cluap1 PF10234.9 ETS82172.1 - 2.1 7.7 8.7 3.9 6.8 8.4 1.4 1 1 0 1 1 1 0 Clusterin-associated protein-1 Peptidase_M24 PF00557.24 ETS82174.1 - 2.9e-06 27.1 0.0 5.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Terpene_synth_C PF03936.16 ETS82176.1 - 0.024 14.0 0.2 0.051 12.9 0.0 1.6 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain LCCL PF03815.19 ETS82178.1 - 2.4e-15 56.4 0.0 4.1e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 LCCL domain DUF4149 PF13664.6 ETS82178.1 - 1.5 9.2 5.9 5.8 7.3 5.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) eIF-5_eIF-2B PF01873.17 ETS82180.1 - 3.5e-42 143.0 0.3 5.1e-42 142.4 0.3 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 ETS82180.1 - 0.023 14.2 0.3 0.046 13.2 0.3 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.10 ETS82180.1 - 1.4 9.3 6.7 1.5 9.2 0.2 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain DAO PF01266.24 ETS82181.1 - 3.2e-42 145.4 0.5 4.3e-42 145.0 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ETS82181.1 - 0.0024 17.2 0.0 0.0055 16.0 0.0 1.5 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 ETS82181.1 - 0.0074 16.5 0.0 0.02 15.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 ETS82181.1 - 0.1 11.1 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) INO80_Ies4 PF08193.11 ETS82182.1 - 1.4e-80 270.8 26.4 1.4e-80 270.8 26.4 1.3 1 1 1 2 2 2 1 INO80 complex subunit Ies4 CLTH PF10607.9 ETS82183.1 - 6.2e-32 110.5 1.2 6.2e-32 110.5 1.2 1.9 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 ETS82183.1 - 2.4e-23 82.5 0.4 4.2e-23 81.7 0.4 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 ETS82183.1 - 1.3e-06 28.1 2.4 5.6e-06 26.1 0.1 2.7 3 0 0 3 3 3 1 LisH EnY2 PF10163.9 ETS82183.1 - 0.049 14.0 0.3 17 5.9 0.0 3.3 2 1 0 2 2 2 0 Transcription factor e(y)2 DUF4012 PF13196.6 ETS82184.1 - 0.18 12.3 0.0 0.21 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4012) GST_N_4 PF17172.4 ETS82185.1 - 7.6e-21 74.7 0.0 1.5e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 ETS82185.1 - 4.2e-14 52.1 0.0 9e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 ETS82185.1 - 1.9e-11 44.3 0.1 7.1e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 ETS82185.1 - 0.00019 21.4 2.8 0.00052 20.0 2.8 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SAM35 PF10806.8 ETS82185.1 - 0.006 16.8 0.1 0.024 14.9 0.1 1.9 1 1 0 2 2 2 1 SAM35, subunit of SAM coomplex adh_short_C2 PF13561.6 ETS82186.1 - 1.2e-49 169.0 0.1 2.8e-49 167.8 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS82186.1 - 9.9e-44 149.1 0.0 1.4e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS82186.1 - 1.5e-07 31.5 0.0 2.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ETS82186.1 - 0.0029 17.0 0.0 0.0039 16.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Flavin_Reduct PF01613.18 ETS82187.1 - 4.2e-18 65.9 0.2 5.5e-18 65.5 0.2 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF4634 PF15465.6 ETS82187.1 - 0.037 14.3 0.0 0.052 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) TPMT PF05724.11 ETS82188.1 - 1.2e-28 100.2 0.0 1.6e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 ETS82188.1 - 6.8e-09 35.8 0.0 1.4e-08 34.8 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS82188.1 - 4e-08 33.8 0.0 2e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS82188.1 - 5.2e-07 30.2 0.0 1.7e-06 28.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS82188.1 - 8.2e-07 29.7 0.0 1.3e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS82188.1 - 1.3e-06 28.2 0.0 2.5e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ETS82188.1 - 0.037 13.4 0.0 0.082 12.3 0.0 1.6 1 1 0 1 1 1 0 Tellurite resistance protein TehB N2227 PF07942.12 ETS82188.1 - 0.18 10.9 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein DUF3433 PF11915.8 ETS82189.1 - 1.3e-34 118.5 24.4 2.5e-22 79.1 3.3 4.1 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Ras PF00071.22 ETS82190.1 - 3.9e-52 176.1 0.0 7.1e-52 175.3 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 ETS82190.1 - 3e-18 66.2 0.0 9.5e-17 61.3 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS82190.1 - 0.00028 20.4 0.0 0.00091 18.7 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ETS82190.1 - 0.0052 16.7 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 ETS82190.1 - 0.032 13.8 0.1 0.43 10.1 0.0 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 ETS82190.1 - 0.055 13.9 0.0 0.076 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 ETS82190.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 ETS82190.1 - 0.16 11.3 0.0 0.38 10.0 0.0 1.6 2 0 0 2 2 2 0 Septin ABC_tran PF00005.27 ETS82191.1 - 2.5e-50 170.5 0.2 6.8e-27 94.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS82191.1 - 5.4e-33 114.8 26.6 1.5e-28 100.3 12.7 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ETS82191.1 - 6.9e-10 38.7 2.8 0.00011 21.7 0.6 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ETS82191.1 - 8.2e-08 31.9 0.4 0.0043 16.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ETS82191.1 - 7.3e-07 29.3 0.1 0.018 15.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETS82191.1 - 1.1e-06 28.7 0.2 0.03 14.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ETS82191.1 - 2.1e-06 28.2 1.0 0.07 13.5 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 ETS82191.1 - 9.1e-06 26.0 0.7 0.1 12.9 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.6 ETS82191.1 - 7.7e-05 23.3 1.0 0.14 12.7 0.2 2.3 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 ETS82191.1 - 8.1e-05 22.6 3.1 0.039 13.7 0.6 3.5 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 ETS82191.1 - 0.00026 21.2 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 ETS82191.1 - 0.00035 20.4 0.0 0.071 12.8 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 ETS82191.1 - 0.00052 20.5 0.0 0.88 10.0 0.0 3.7 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 ETS82191.1 - 0.00094 19.0 0.0 0.07 12.9 0.0 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein DUF815 PF05673.13 ETS82191.1 - 0.0011 18.2 0.0 0.59 9.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 ETS82191.1 - 0.0025 17.0 0.0 0.29 10.3 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 ETS82191.1 - 0.0034 17.0 2.4 0.83 9.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 ETS82191.1 - 0.0047 17.1 3.2 0.71 9.9 0.2 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain RNA_helicase PF00910.22 ETS82191.1 - 0.0048 17.3 0.1 14 6.1 0.0 3.5 3 0 0 3 3 3 0 RNA helicase Dynamin_N PF00350.23 ETS82191.1 - 0.0061 16.6 0.3 0.23 11.5 0.0 2.3 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.6 ETS82191.1 - 0.0083 15.9 0.2 1.7 8.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 ETS82191.1 - 0.011 15.7 0.4 3.8 7.4 0.1 3.0 3 0 0 3 3 3 0 NACHT domain TrwB_AAD_bind PF10412.9 ETS82191.1 - 0.012 14.5 0.3 0.25 10.2 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain GTP_EFTU PF00009.27 ETS82191.1 - 0.012 15.1 0.1 2 7.9 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 ETS82191.1 - 0.018 14.6 0.1 3.6 7.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 ETS82191.1 - 0.019 14.0 0.2 0.16 11.0 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Ploopntkinase3 PF18751.1 ETS82191.1 - 0.021 14.7 0.1 0.55 10.1 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 ETS82191.1 - 0.022 15.3 0.0 5.1 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ETS82191.1 - 0.036 13.7 0.4 1.9 8.0 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 ETS82191.1 - 0.037 13.9 0.2 13 5.6 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.6 ETS82191.1 - 0.041 14.1 0.8 3.1 8.1 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 ETS82191.1 - 0.047 13.0 0.1 7.2 5.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 ETS82191.1 - 0.094 12.9 0.1 22 5.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF3987 PF13148.6 ETS82191.1 - 0.13 11.2 0.2 3.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) FtsK_SpoIIIE PF01580.18 ETS82191.1 - 0.13 11.5 0.6 12 5.1 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.18 ETS82191.1 - 0.22 10.8 0.1 23 4.1 0.0 2.3 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.15 ETS82191.1 - 0.23 11.4 2.5 25 4.8 0.0 3.2 3 0 0 3 3 3 0 NTPase DLIC PF05783.11 ETS82191.1 - 0.25 10.1 0.1 4.2 6.1 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) PRK PF00485.18 ETS82191.1 - 0.33 10.7 1.1 0.95 9.2 0.2 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Phage_holin_4_2 PF04020.13 ETS82192.1 - 0.068 13.8 4.6 0.35 11.6 0.1 2.5 2 0 0 2 2 2 0 Mycobacterial 4 TMS phage holin, superfamily IV DUF3341 PF11821.8 ETS82192.1 - 0.15 11.7 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Saf_2TM PF18303.1 ETS82192.1 - 0.21 11.2 2.7 4.2 7.0 0.1 2.8 2 1 1 3 3 3 0 SAVED-fused 2TM effector domain YrhK PF14145.6 ETS82192.1 - 1.4 8.9 24.8 3.2 7.7 0.1 4.7 3 1 2 5 5 5 0 YrhK-like protein DUF2583 PF10762.9 ETS82192.1 - 5.6 7.5 11.7 0.51 10.8 0.6 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2583) Mcp5_PH PF12814.7 ETS82193.1 - 1.3e-45 154.4 0.0 3e-45 153.3 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.12 ETS82193.1 - 3 7.9 22.4 4.8 7.3 19.9 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 ETS82193.1 - 7.3 7.0 19.8 4.3 7.7 17.4 1.9 1 1 0 1 1 1 0 Fez1 OTU PF02338.19 ETS82194.1 - 4.1e-26 92.0 0.0 3e-25 89.2 0.0 2.2 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 ETS82194.1 - 5.8e-05 22.7 0.0 0.0076 15.7 0.0 2.5 3 0 0 3 3 3 2 Peptidase C65 Otubain Red1 PF07964.11 ETS82194.1 - 5.8 5.0 8.4 3 6.0 6.3 1.5 1 1 0 1 1 1 0 Rec10 / Red1 DUF883 PF05957.13 ETS82194.1 - 6.6 7.4 15.8 3.4 8.4 0.0 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Aldedh PF00171.22 ETS82195.1 - 1.3e-13 50.3 6.6 2.3e-09 36.3 4.2 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.17 ETS82195.1 - 0.0051 16.0 0.0 0.0078 15.4 0.0 1.2 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PALP PF00291.25 ETS82196.1 - 6.7e-60 203.0 0.5 1.3e-58 198.7 0.5 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IlvN PF07991.12 ETS82197.1 - 1.7e-45 154.6 0.0 2.8e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 ETS82197.1 - 4.9e-41 140.4 0.0 8e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 ETS82197.1 - 0.077 13.6 0.8 0.17 12.5 0.0 2.1 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent UQ_con PF00179.26 ETS82198.1 - 2.4e-35 121.2 0.0 3.5e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 ETS82198.1 - 0.0089 15.9 0.1 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 ETS82198.1 - 0.035 14.4 0.3 0.065 13.5 0.3 1.5 1 1 0 1 1 1 0 RWD domain Chitin_synth_1 PF01644.17 ETS82199.1 - 3.1e-69 232.1 0.0 4.6e-69 231.5 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ETS82199.1 - 1.8e-27 95.0 0.0 3.4e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ETS82199.1 - 4.2e-25 88.3 1.5 6.4e-21 74.6 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ETS82199.1 - 7.1e-07 29.3 7.8 9.6e-06 25.6 7.8 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Opy2 PF09463.10 ETS82200.1 - 4.1e-10 39.8 21.4 6.5e-10 39.2 21.4 1.3 1 0 0 1 1 1 1 Opy2 protein Serglycin PF04360.12 ETS82200.1 - 0.024 14.6 1.8 0.07 13.1 1.8 1.8 1 0 0 1 1 1 0 Serglycin Con-6 PF10346.9 ETS82201.1 - 9.8e-29 99.1 10.6 1.5e-17 63.3 1.0 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.7 ETS82201.1 - 0.064 13.1 3.0 0.13 12.0 0.3 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein Glyco_transf_8C PF08437.10 ETS82201.1 - 0.52 10.4 2.2 12 6.1 0.2 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal TMEM234 PF10639.9 ETS82202.1 - 2.3e-36 124.4 0.0 2.9e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 ETS82202.1 - 3.8e-06 27.1 3.1 0.008 16.3 2.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF485 PF04341.12 ETS82202.1 - 0.026 14.4 0.8 0.94 9.5 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function, DUF485 DUF5640 PF18692.1 ETS82203.1 - 0.011 15.8 0.6 0.065 13.3 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5640) CH PF00307.31 ETS82204.1 - 3.2e-70 233.3 0.1 3.2e-17 62.7 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 ETS82204.1 - 1.1e-05 25.8 0.3 0.00011 22.5 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 ETS82204.1 - 0.0033 16.9 0.3 1.4 8.7 0.1 3.4 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 ETS82204.1 - 0.027 14.4 1.3 0.91 9.6 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain MBOAT PF03062.19 ETS82205.1 - 1.6e-42 146.1 18.8 1.6e-42 146.1 18.8 2.2 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 ETS82205.1 - 5.6e-06 26.5 4.6 1.4e-05 25.3 4.6 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Epimerase PF01370.21 ETS82206.1 - 4e-20 72.3 0.0 5.7e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS82206.1 - 5.9e-12 45.6 0.0 7.4e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ETS82206.1 - 2.8e-08 33.1 0.0 3.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ETS82206.1 - 1.5e-07 30.9 0.0 1.1e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 ETS82206.1 - 2e-05 24.1 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 ETS82206.1 - 7.8e-05 22.6 0.0 0.00024 21.0 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ETS82206.1 - 0.00013 21.2 0.0 0.00023 20.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 ETS82206.1 - 0.00018 21.5 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 ETS82206.1 - 0.00069 18.8 0.0 0.001 18.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Kelch_1 PF01344.25 ETS82206.1 - 0.023 14.3 0.3 1.1 8.9 0.0 2.8 2 0 0 2 2 2 0 Kelch motif NmrA PF05368.13 ETS82206.1 - 0.039 13.5 0.0 0.32 10.5 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family FAD_binding_3 PF01494.19 ETS82207.1 - 1.8e-20 73.5 1.0 4.1e-20 72.3 1.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS82207.1 - 6.5e-05 22.7 6.6 0.0012 18.5 4.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 ETS82207.1 - 0.00089 18.4 0.0 0.077 12.0 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_2 PF07992.14 ETS82207.1 - 0.0063 15.8 0.5 0.015 14.5 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS82207.1 - 0.0093 16.5 2.4 0.045 14.3 1.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS82207.1 - 0.012 15.8 0.7 0.032 14.5 0.7 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS82207.1 - 0.078 12.2 0.0 1.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Dabb PF07876.12 ETS82207.1 - 0.18 12.5 0.1 1.4 9.6 0.2 2.2 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain NAD_binding_9 PF13454.6 ETS82207.1 - 0.29 11.1 1.4 1.9 8.4 1.4 2.4 1 1 0 1 1 1 0 FAD-NAD(P)-binding RCR PF12273.8 ETS82208.1 - 0.0059 17.3 0.0 0.0068 17.1 0.0 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TRAF_BIRC3_bd PF16673.5 ETS82209.1 - 2.3 8.1 4.7 4.7 7.1 0.8 2.7 2 1 1 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain UTP15_C PF09384.10 ETS82210.1 - 2.3e-51 173.4 0.0 3.3e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 ETS82210.1 - 9.6e-16 57.9 5.7 0.0029 18.4 0.0 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS82210.1 - 1.5e-05 25.2 0.2 0.41 11.0 0.0 4.4 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 ETS82210.1 - 0.006 15.9 0.1 3.1 7.0 0.0 2.2 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus HEPN_AbiU2 PF18734.1 ETS82210.1 - 0.077 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 AbiU2 ECH_1 PF00378.20 ETS82211.1 - 7.5e-40 136.8 0.0 1.9e-39 135.5 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ETS82211.1 - 7.4e-32 111.2 0.0 9.3e-29 101.0 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase RCR PF12273.8 ETS82212.1 - 0.0018 18.9 4.9 0.0042 17.7 4.9 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF4381 PF14316.6 ETS82212.1 - 0.019 15.2 0.1 0.03 14.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Chordopox_A13L PF05961.11 ETS82212.1 - 0.029 14.6 0.1 0.051 13.8 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF1180 PF06679.12 ETS82212.1 - 0.072 13.5 1.0 0.29 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) EphA2_TM PF14575.6 ETS82212.1 - 0.12 13.3 0.0 0.14 13.0 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cellulase PF00150.18 ETS82213.1 - 5.9e-17 62.0 0.8 8.5e-17 61.5 0.1 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 ETS82213.1 - 3.6e-13 49.2 7.4 3.6e-13 49.2 7.4 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 ETS82213.1 - 0.00012 21.3 0.0 0.00018 20.7 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 ETS82213.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase MGC-24 PF05283.11 ETS82213.1 - 4.9 7.6 18.2 9.5 6.7 18.2 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin MSP1_C PF07462.11 ETS82213.1 - 9.4 4.8 7.2 13 4.3 7.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus zf-CCHC PF00098.23 ETS82214.1 - 8.7e-57 186.8 104.1 2.3e-07 30.6 3.0 10.5 11 0 0 11 11 11 10 Zinc knuckle zf-CCHC_2 PF13696.6 ETS82214.1 - 5.4e-12 45.3 79.9 0.0044 16.8 2.3 10.4 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_4 PF14392.6 ETS82214.1 - 1.4e-09 37.5 57.7 0.14 11.9 0.3 10.6 11 0 0 11 11 11 8 Zinc knuckle zf-CCHC_3 PF13917.6 ETS82214.1 - 1.3e-08 34.6 72.0 0.012 15.5 0.7 10.1 2 2 8 10 10 10 9 Zinc knuckle zf-CCHC_6 PF15288.6 ETS82214.1 - 0.0025 17.6 82.2 0.026 14.3 2.0 10.3 8 2 2 10 10 10 6 Zinc knuckle zf-C2H2_10 PF16588.5 ETS82214.1 - 0.0053 16.5 2.6 0.0053 16.5 2.6 9.5 10 0 0 10 10 10 3 C2H2 zinc-finger MFS_1 PF07690.16 ETS82216.1 - 3.3e-39 134.8 53.9 1.1e-38 133.2 48.7 3.2 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS82216.1 - 7.3e-11 41.2 12.7 7.3e-11 41.2 12.7 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 ETS82216.1 - 0.00014 20.3 1.5 0.00014 20.3 1.5 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family CMD PF02627.20 ETS82217.1 - 9.4e-09 35.2 1.5 5.7e-08 32.7 0.9 2.2 2 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family BRCA2 PF00634.18 ETS82217.1 - 0.14 11.9 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 BRCA2 repeat DUF4131 PF13567.6 ETS82218.1 - 0.063 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MerR-DNA-bind PF09278.11 ETS82218.1 - 8 7.1 9.3 2.5 8.7 5.4 2.3 2 1 0 2 2 2 0 MerR, DNA binding Pkinase PF00069.25 ETS82219.1 - 8.4e-08 31.9 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 ETS82219.1 - 1.1e-07 32.1 3.2 0.03 14.2 2.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 ETS82219.1 - 5.9e-06 25.8 0.0 0.07 12.5 0.0 3.0 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 ETS82219.1 - 5e-05 22.7 0.0 0.00011 21.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 ETS82219.1 - 0.00097 18.8 0.1 0.17 11.5 0.1 2.4 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 ETS82219.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Aldo_ket_red PF00248.21 ETS82220.1 - 3.8e-11 42.7 0.0 4.9e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Maf1 PF09174.10 ETS82221.1 - 2.2e-58 197.3 0.0 5.7e-58 195.9 0.0 1.7 2 0 0 2 2 2 1 Maf1 regulator Clat_adaptor_s PF01217.20 ETS82221.1 - 7.1e-50 168.6 0.9 1.1e-49 168.1 0.9 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Egh16-like PF11327.8 ETS82223.1 - 1.2e-68 231.2 9.1 1.6e-68 230.7 9.1 1.2 1 0 0 1 1 1 1 Egh16-like virulence factor AMP-binding PF00501.28 ETS82224.1 - 2.1e-81 273.7 0.0 2.7e-81 273.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS82224.1 - 1.1e-11 45.5 0.8 1.1e-11 45.5 0.8 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain REPA_OB_2 PF16900.5 ETS82225.1 - 0.004 17.0 0.0 0.0091 15.9 0.0 1.5 1 0 0 1 1 1 1 Replication protein A OB domain SNF2_N PF00176.23 ETS82226.1 - 6.4e-09 35.0 0.0 1e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SNF2_N PF00176.23 ETS82227.1 - 6.8e-18 64.5 0.1 9.3e-18 64.0 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS82227.1 - 5.1e-13 49.3 0.0 1.4e-12 47.9 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 ETS82227.1 - 0.0039 17.2 4.0 0.0039 17.2 4.0 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ETS82227.1 - 0.004 17.1 9.7 0.0085 16.0 9.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ETS82227.1 - 0.0072 16.2 8.9 0.017 15.0 8.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FAM76 PF16046.5 ETS82227.1 - 0.01 15.2 0.0 0.028 13.8 0.0 1.7 2 0 0 2 2 2 0 FAM76 protein zf-RING_2 PF13639.6 ETS82227.1 - 0.18 12.2 10.1 0.4 11.1 10.1 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 ETS82227.1 - 0.32 10.9 9.0 0.88 9.5 9.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ETS82227.1 - 0.87 9.8 9.4 2.1 8.6 9.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ETS82227.1 - 2.4 8.1 12.1 6 6.8 12.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 UcrQ PF02939.16 ETS82229.1 - 2.5e-36 123.5 0.9 2.9e-36 123.3 0.9 1.1 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.25 ETS82230.1 - 6.3e-23 81.7 7.4 1.3e-22 80.7 7.4 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 ETS82230.1 - 0.00041 19.5 4.9 0.00055 19.1 4.9 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial GatB_Yqey PF02637.18 ETS82230.1 - 0.078 12.9 1.4 0.15 11.9 1.4 1.5 1 1 0 1 1 1 0 GatB domain Peptidase_M17_N PF02789.17 ETS82231.1 - 0.046 13.6 0.3 0.046 13.6 0.3 1.5 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Yae1_N PF09811.9 ETS82232.1 - 5.6e-06 26.0 10.8 1.1e-05 25.0 10.8 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Trns_repr_metal PF02583.17 ETS82232.1 - 0.086 13.2 0.1 0.16 12.4 0.1 1.3 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor tRNA-synt_1g PF09334.11 ETS82233.1 - 3.9e-147 490.1 0.0 4.9e-147 489.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ETS82233.1 - 4.5e-07 28.5 1.6 0.00063 18.1 0.0 3.1 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) MMU163 PF17119.5 ETS82233.1 - 0.19 10.8 1.6 0.32 10.1 1.6 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Med19 PF10278.9 ETS82233.1 - 1 9.2 8.0 2.2 8.2 8.0 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Atrophin-1 PF03154.15 ETS82233.1 - 5 5.3 8.5 7.5 4.7 8.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family Glyco_hydro_92 PF07971.12 ETS82234.1 - 1.1e-132 443.3 0.0 1.4e-132 442.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 ETS82234.1 - 6.5e-59 199.7 0.1 1e-58 199.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Nucleopor_Nup85 PF07575.13 ETS82235.1 - 1e-05 24.3 0.1 0.06 11.9 0.0 3.3 3 0 0 3 3 3 2 Nup85 Nucleoporin cIII PF08134.11 ETS82235.1 - 0.023 14.5 0.9 0.12 12.2 0.1 2.3 2 0 0 2 2 2 0 cIII protein family SDA1 PF05285.12 ETS82235.1 - 2.9 7.2 29.2 4.8 6.5 29.2 1.2 1 0 0 1 1 1 0 SDA1 CDC27 PF09507.10 ETS82235.1 - 5.6 6.2 12.0 9 5.6 12.0 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ADH_N PF08240.12 ETS82236.1 - 8.9e-26 89.9 2.0 2.1e-25 88.7 2.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS82236.1 - 1.5e-18 67.0 0.3 2.6e-18 66.3 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ETS82236.1 - 0.0043 16.4 0.4 0.0073 15.6 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 ETS82236.1 - 0.0079 16.5 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Imm70 PF15601.6 ETS82236.1 - 0.21 11.1 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 70 zf-AN1 PF01428.16 ETS82237.1 - 6.6e-13 48.6 8.9 9e-13 48.2 8.6 1.4 1 1 0 1 1 1 1 AN1-like Zinc finger IBR PF01485.21 ETS82237.1 - 2.1 8.6 11.8 9.2 6.6 11.7 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain HhH-GPD PF00730.25 ETS82238.1 - 3.4e-20 72.5 0.0 6.6e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ETS82238.1 - 7.3e-07 28.7 0.0 1.7e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF676 PF05057.14 ETS82239.1 - 3.5e-53 180.4 0.0 5.3e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 ETS82239.1 - 1.2e-05 25.3 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 ETS82239.1 - 8.6e-05 23.2 0.0 0.00027 21.6 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ETS82239.1 - 0.00011 22.0 0.0 0.0013 18.5 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 ETS82239.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) CHORD PF04968.12 ETS82240.1 - 0.0017 19.0 1.0 0.0036 18.0 1.0 1.6 1 0 0 1 1 1 1 CHORD WRC PF08879.10 ETS82240.1 - 0.038 13.7 0.6 0.095 12.4 0.6 1.6 1 0 0 1 1 1 0 WRC BTK PF00779.19 ETS82240.1 - 0.054 13.3 2.8 0.11 12.3 2.8 1.5 1 0 0 1 1 1 0 BTK motif DUF5393 PF17371.2 ETS82240.1 - 1.2 7.2 10.0 1.8 6.6 10.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5393) zf-CCCH_2 PF14608.6 ETS82240.1 - 2.6 8.6 4.4 5.5 7.6 4.4 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF952 PF06108.12 ETS82241.1 - 1.9e-16 59.9 0.0 2.8e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Mito_fiss_reg PF05308.11 ETS82242.1 - 0.041 14.0 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator CASP_C PF08172.12 ETS82242.1 - 0.68 9.2 3.6 0.6 9.4 1.4 1.8 2 0 0 2 2 2 0 CASP C terminal DUF4140 PF13600.6 ETS82242.1 - 0.71 10.3 2.6 8.9 6.8 0.2 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) MMR_HSR1_C PF08438.10 ETS82243.1 - 3.1e-30 105.0 0.0 8.8e-30 103.6 0.0 1.7 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 ETS82243.1 - 6.3e-17 61.7 0.0 1.4e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ETS82243.1 - 1.5e-07 31.1 0.1 0.00017 21.1 0.0 2.7 3 0 0 3 3 3 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 ETS82243.1 - 0.0018 17.9 0.1 0.71 9.4 0.0 2.7 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ETS82243.1 - 0.0023 17.9 0.4 0.32 10.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 ETS82243.1 - 0.012 16.2 0.0 0.075 13.5 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 ETS82243.1 - 0.041 14.0 0.1 0.24 11.4 0.2 2.0 2 0 0 2 2 2 0 Dynamin family MMR_HSR1_Xtn PF16897.5 ETS82243.1 - 0.045 13.8 0.4 0.098 12.7 0.1 1.7 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Ploopntkinase3 PF18751.1 ETS82243.1 - 0.11 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 ETS82243.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 ETS82243.1 - 0.19 12.0 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dioxygenase_C PF00775.21 ETS82244.1 - 1.6e-10 40.8 0.0 2.4e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase SET PF00856.28 ETS82245.1 - 0.0054 17.1 0.0 0.025 15.0 0.0 2.1 1 1 0 1 1 1 1 SET domain Fungal_trans PF04082.18 ETS82246.1 - 3e-33 115.0 1.6 5.9e-33 114.0 1.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS82246.1 - 2.9e-10 40.1 11.1 5.2e-10 39.3 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 ETS82246.1 - 0.1 12.7 0.5 0.3 11.2 0.5 1.8 1 0 0 1 1 1 0 bZIP transcription factor GDPD PF03009.17 ETS82247.1 - 7.2e-29 101.3 0.0 1.4e-28 100.4 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family WD40 PF00400.32 ETS82248.1 - 8.7e-31 105.5 28.6 8.9e-06 26.4 0.1 10.4 10 1 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS82248.1 - 2.6e-14 53.3 7.0 0.0046 17.2 0.3 6.9 3 3 5 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ETS82248.1 - 0.0038 15.9 0.1 0.031 12.9 0.2 2.1 1 1 1 2 2 2 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 ETS82248.1 - 0.0056 16.7 0.1 2.8 8.0 0.0 3.7 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region DUF1513 PF07433.11 ETS82248.1 - 0.0096 15.0 6.6 0.039 13.0 0.0 3.6 4 1 1 5 5 5 1 Protein of unknown function (DUF1513) Ge1_WD40 PF16529.5 ETS82248.1 - 0.032 13.2 5.5 17 4.2 0.1 4.4 3 2 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 ETS82248.1 - 0.043 13.8 1.6 21 5.2 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat SdrG_C_C PF10425.9 ETS82248.1 - 0.1 12.6 0.1 0.28 11.3 0.1 1.7 2 0 0 2 2 2 0 C-terminus of bacterial fibrinogen-binding adhesin Proteasome_A_N PF10584.9 ETS82248.1 - 4 7.2 5.3 1.7 8.4 0.0 3.2 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature HET PF06985.11 ETS82249.1 - 4.4e-08 33.6 0.0 6.5e-05 23.3 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_tran_28_C PF04101.16 ETS82250.1 - 4.2e-16 59.4 0.0 2.2e-14 53.8 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain MRP-S28 PF10213.9 ETS82251.1 - 4e-46 156.6 0.8 4e-46 156.6 0.8 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein MAM PF00629.23 ETS82251.1 - 0.005 16.8 0.1 0.013 15.4 0.1 1.7 2 0 0 2 2 2 1 MAM domain, meprin/A5/mu Wbp11 PF09429.10 ETS82251.1 - 0.82 10.1 4.5 0.17 12.3 0.6 1.9 2 0 0 2 2 2 0 WW domain binding protein 11 CHIP_TPR_N PF18391.1 ETS82251.1 - 5 8.0 7.3 1.2 10.0 1.0 2.9 3 0 0 3 3 3 0 CHIP N-terminal tetratricopeptide repeat domain DUF4276 PF14103.6 ETS82252.1 - 0.075 13.3 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) Glyco_hydro_71 PF03659.14 ETS82253.1 - 1e-116 389.8 5.3 1.2e-116 389.6 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 VWA PF00092.28 ETS82253.1 - 0.098 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain adh_short_C2 PF13561.6 ETS82254.1 - 1.2e-47 162.5 0.1 2.5e-40 138.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS82254.1 - 7.3e-44 149.6 0.0 9.7e-44 149.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS82254.1 - 5.9e-14 52.4 0.0 8.3e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS82254.1 - 0.0088 15.5 0.1 0.087 12.3 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thioredoxin_15 PF18403.1 ETS82254.1 - 0.01 15.8 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain STAS PF01740.21 ETS82254.1 - 0.058 13.0 0.0 0.43 10.2 0.0 2.1 2 0 0 2 2 2 0 STAS domain Ribosomal_L26 PF16906.5 ETS82254.1 - 0.11 12.9 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal Acetyltransf_1 PF00583.25 ETS82255.1 - 1.9e-12 47.5 0.0 2.8e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ETS82255.1 - 6.2e-07 29.3 0.1 1e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 ETS82255.1 - 2e-06 27.8 0.1 2.9e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS82255.1 - 3.9e-06 27.2 0.0 7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETS82255.1 - 0.027 14.5 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4646 PF15496.6 ETS82256.1 - 1.2 9.7 3.9 1.3 9.7 0.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4646) IF-2B PF01008.17 ETS82257.1 - 7.9e-31 107.3 0.0 1.2e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family NIF PF03031.18 ETS82258.1 - 7.8e-56 188.2 0.0 1.2e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF1761 PF08570.10 ETS82259.1 - 2.4e-26 92.4 3.7 2.8e-26 92.2 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Phage_holin_2_1 PF04971.12 ETS82259.1 - 0.073 13.1 1.5 0.12 12.4 0.1 2.0 1 1 1 2 2 2 0 Bacteriophage P21 holin S Ribosomal_L7Ae PF01248.26 ETS82260.1 - 1.8e-20 72.5 0.6 8.2e-20 70.3 0.6 2.0 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Rgp1 PF08737.10 ETS82260.1 - 1.4 8.0 5.8 1.5 7.9 0.0 2.1 2 0 0 2 2 2 0 Rgp1 ERG4_ERG24 PF01222.17 ETS82261.1 - 5.8e-141 470.1 19.3 6.8e-141 469.9 19.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF5127 PF17168.4 ETS82263.1 - 8e-84 281.0 5.5 1.2e-83 280.4 5.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 ETS82263.1 - 8.2e-73 243.7 0.2 1.3e-72 243.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 ETS82263.1 - 1e-67 227.7 0.2 3.1e-67 226.2 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 ETS82263.1 - 4.1e-06 26.3 0.0 1.2e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) CotH PF08757.11 ETS82263.1 - 0.23 10.9 2.0 0.4 10.1 2.0 1.3 1 0 0 1 1 1 0 CotH kinase protein Ribosomal_L5e PF17144.4 ETS82265.1 - 6.7e-82 273.3 0.3 1.1e-81 272.7 0.3 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 ETS82265.1 - 9.4e-35 119.4 9.2 9.4e-35 119.4 9.2 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 ETS82265.1 - 0.12 12.8 0.1 0.12 12.8 0.1 1.7 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast HAD_2 PF13419.6 ETS82266.1 - 5e-05 23.5 0.0 9.6e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETS82266.1 - 0.034 14.4 0.0 0.078 13.3 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ETS82266.1 - 0.038 14.1 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like AGTRAP PF06396.11 ETS82268.1 - 3 7.6 4.8 6.7 6.5 0.1 3.1 3 0 0 3 3 3 0 Angiotensin II, type I receptor-associated protein (AGTRAP) FAD_binding_3 PF01494.19 ETS82269.1 - 4.7e-19 68.8 0.4 3.6e-11 42.9 0.1 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 ETS82269.1 - 3.2e-05 23.7 0.1 4.6e-05 23.2 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS82269.1 - 6e-05 23.2 0.0 0.00015 21.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS82269.1 - 0.0019 17.3 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DUF2063 PF09836.9 ETS82269.1 - 0.075 13.3 0.0 2.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Putative DNA-binding domain Pyr_redox PF00070.27 ETS82269.1 - 0.17 12.5 0.0 0.4 11.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ArfGap PF01412.18 ETS82270.1 - 1.7e-38 131.3 0.2 1.7e-38 131.3 0.2 2.5 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.31 ETS82270.1 - 0.043 13.7 0.1 0.31 11.0 0.0 2.5 3 0 0 3 3 3 0 UBA/TS-N domain Dynamin_N PF00350.23 ETS82271.1 - 7.2e-12 45.7 0.0 4.2e-11 43.2 0.0 2.4 2 1 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 ETS82271.1 - 1.7e-05 24.8 2.3 0.00054 19.9 0.0 3.6 4 1 0 4 4 4 1 RsgA GTPase MMR_HSR1 PF01926.23 ETS82271.1 - 1.8e-05 24.8 0.0 0.00076 19.5 0.0 3.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ETS82271.1 - 0.00035 21.0 0.1 0.0026 18.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 ETS82271.1 - 0.0015 19.1 0.1 0.01 16.4 0.0 2.3 2 0 0 2 2 2 1 ABC transporter Baculo_PEP_C PF04513.12 ETS82271.1 - 0.0093 16.0 5.8 1.3 9.1 0.2 3.5 4 0 0 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_23 PF13476.6 ETS82271.1 - 0.018 15.5 3.4 2.4 8.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 ETS82271.1 - 0.055 13.7 0.0 0.48 10.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain QueF PF14489.6 ETS82271.1 - 0.055 13.6 0.0 0.55 10.4 0.0 2.4 2 0 0 2 2 2 0 QueF-like protein CCDC-167 PF15188.6 ETS82271.1 - 0.21 11.9 8.9 0.48 10.8 4.6 2.9 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Pox_A3L PF05288.11 ETS82271.1 - 0.21 11.6 2.0 10 6.2 0.0 2.8 3 0 0 3 3 3 0 Poxvirus A3L Protein Methyltransf_23 PF13489.6 ETS82272.1 - 7.6e-17 61.6 0.0 1.1e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS82272.1 - 5.5e-07 30.2 0.0 1.3e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS82272.1 - 2.2e-06 28.3 0.0 5.6e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS82272.1 - 5.3e-06 26.3 0.0 4.2e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS82272.1 - 0.018 14.6 0.0 0.094 12.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.18 ETS82272.1 - 0.17 11.2 0.0 0.48 9.7 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Pyridoxal_deC PF00282.19 ETS82273.1 - 1.6e-25 89.6 0.0 2.8e-25 88.8 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 ETS82273.1 - 0.00046 19.6 0.0 0.00059 19.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 ETS82273.1 - 0.02 14.1 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II DUF2462 PF09495.10 ETS82274.1 - 1.2e-18 67.5 8.6 1.2e-18 67.5 8.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) FCH PF00611.23 ETS82275.1 - 2.2e-24 85.5 0.1 2.2e-24 85.5 0.1 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 ETS82275.1 - 1.5e-20 72.8 0.5 1.7e-12 47.0 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 ETS82275.1 - 4.3e-16 58.2 0.1 3.4e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.22 ETS82275.1 - 2.7e-15 56.0 5.6 4.2e-15 55.4 5.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.17 ETS82275.1 - 0.00016 21.3 0.1 0.097 12.4 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 ETS82275.1 - 0.00025 21.3 0.5 0.098 13.0 0.2 2.6 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_10 PF17902.1 ETS82275.1 - 0.01 15.9 0.0 1.8 8.7 0.0 2.9 3 0 0 3 3 3 0 SH3 domain C1_2 PF03107.16 ETS82275.1 - 0.01 16.1 5.0 0.019 15.2 5.0 1.4 1 0 0 1 1 1 0 C1 domain Flot PF15975.5 ETS82275.1 - 0.051 13.8 0.2 0.099 12.8 0.2 1.4 1 0 0 1 1 1 0 Flotillin SH3_16 PF18348.1 ETS82275.1 - 0.1 12.4 0.2 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain Tox-REase-5 PF15648.6 ETS82275.1 - 0.15 12.6 2.2 0.38 11.3 2.2 1.6 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 5 DEAD PF00270.29 ETS82276.1 - 5.2e-36 124.0 0.6 3.6e-35 121.3 0.3 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS82276.1 - 9.3e-25 87.1 0.0 2.3e-24 85.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS82276.1 - 2.9e-07 30.7 0.0 5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ETS82276.1 - 0.00024 20.9 0.1 0.00041 20.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ETS82276.1 - 0.0015 18.9 0.2 0.027 14.8 0.2 2.3 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 ETS82276.1 - 0.022 14.6 0.8 5.2 6.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 ETS82276.1 - 0.022 15.0 0.8 0.58 10.4 0.7 2.9 2 1 0 2 2 2 0 AAA domain RnfC_N PF13375.6 ETS82276.1 - 0.029 14.3 0.3 0.1 12.6 0.1 1.9 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain CFEM PF05730.11 ETS82277.1 - 0.0038 17.3 6.9 0.0074 16.4 6.9 1.4 1 0 0 1 1 1 1 CFEM domain Glycophorin_A PF01102.18 ETS82277.1 - 2.9 8.2 8.5 0.18 12.0 1.2 2.9 3 0 0 3 3 3 0 Glycophorin A Glyco_transf_90 PF05686.12 ETS82278.1 - 7.2e-17 61.4 0.0 3.7e-14 52.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 90 Spo7_2_N PF15407.6 ETS82278.1 - 0.023 14.3 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 SHNi-TPR PF10516.9 ETS82280.1 - 1.5e-13 50.0 0.6 1.5e-13 50.0 0.6 2.8 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.6 ETS82280.1 - 0.00015 22.0 10.5 0.0018 18.5 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ETS82280.1 - 0.00045 20.8 17.4 0.0012 19.4 2.2 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ETS82280.1 - 0.01 15.9 18.1 0.3 11.3 2.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS82280.1 - 0.014 15.6 2.9 1.8 8.9 0.6 3.4 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 ETS82280.1 - 0.048 13.5 7.5 0.19 11.6 1.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 ETS82280.1 - 0.072 13.2 6.4 0.3 11.1 0.4 3.2 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_11 PF13414.6 ETS82280.1 - 0.11 12.2 12.8 0.2 11.4 1.8 4.4 5 0 0 5 5 5 0 TPR repeat TPR_8 PF13181.6 ETS82280.1 - 0.16 12.2 10.4 3.2 8.2 1.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 ETS82280.1 - 0.16 11.8 8.2 8.8 6.4 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1844 PF08899.11 ETS82280.1 - 0.18 12.1 3.9 0.26 11.6 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) TPR_3 PF07720.12 ETS82280.1 - 0.68 10.0 8.4 0.089 12.8 3.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 ETS82280.1 - 1.1 10.3 11.2 8.4 7.5 0.3 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat CDC50 PF03381.15 ETS82281.1 - 2.5e-99 332.3 1.0 3e-99 332.1 1.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family MOSC PF03473.17 ETS82282.1 - 5.1e-25 88.0 0.0 1e-24 87.0 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.27 ETS82282.1 - 1.7e-09 37.5 0.7 4.4e-09 36.2 0.7 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 ETS82282.1 - 1.2e-08 35.6 0.0 1.1e-07 32.5 0.0 2.4 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain 3-alpha PF03475.14 ETS82282.1 - 3e-05 23.8 0.1 6.6e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 3-alpha domain NAD_binding_6 PF08030.12 ETS82282.1 - 0.046 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Ferric reductase NAD binding domain SNF2_N PF00176.23 ETS82283.1 - 7.4e-25 87.4 0.0 1.4e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 ETS82283.1 - 7.2e-07 29.4 0.4 2.7e-06 27.5 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ETS82283.1 - 1.7e-06 28.4 0.1 3.4e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TRAP_alpha PF03896.16 ETS82283.1 - 6.4 5.9 8.9 15 4.7 8.9 1.7 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Glyco_hydro_76 PF03663.14 ETS82284.1 - 6.9e-158 525.9 10.5 8.1e-158 525.7 10.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 ETS82284.1 - 0.0063 15.6 10.5 0.26 10.3 0.1 3.3 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 MFS_1 PF07690.16 ETS82285.1 - 1.7e-29 102.8 67.4 2.6e-20 72.7 30.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2388 PF09498.10 ETS82285.1 - 0.2 11.6 1.5 0.24 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) Pro-kuma_activ PF09286.11 ETS82287.1 - 5.9e-47 159.5 0.1 2.3e-46 157.6 0.0 1.8 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ETS82287.1 - 0.01 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Subtilase family WD40 PF00400.32 ETS82288.1 - 2.1e-38 129.6 19.3 8.4e-10 39.1 0.0 7.8 8 0 0 8 8 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS82288.1 - 3.7e-12 46.4 0.4 0.0077 16.5 0.0 4.9 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS82288.1 - 1.8e-07 30.4 0.1 0.5 9.3 0.0 4.5 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ETS82288.1 - 9.2e-07 27.9 1.1 0.037 12.7 0.0 3.7 3 1 0 3 3 3 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 ETS82288.1 - 2.3e-05 23.5 0.2 2.3e-05 23.5 0.2 2.1 2 1 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Coatomer_WDAD PF04053.14 ETS82288.1 - 0.0011 18.1 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region Frtz PF11768.8 ETS82288.1 - 0.0029 16.0 0.0 0.007 14.7 0.0 1.6 2 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz HPS3_N PF14761.6 ETS82288.1 - 0.0042 16.6 0.0 0.042 13.4 0.0 2.2 2 0 0 2 2 2 1 Hermansky-Pudlak syndrome 3 Hira PF07569.11 ETS82288.1 - 0.098 12.4 0.8 24 4.6 0.1 3.0 1 1 1 2 2 2 0 TUP1-like enhancer of split Utp8 PF10395.9 ETS82288.1 - 0.27 9.7 0.0 0.47 8.9 0.0 1.3 1 1 0 1 1 1 0 Utp8 family MAGI_u5 PF16666.5 ETS82288.1 - 3 8.0 6.1 2.3 8.4 3.4 2.1 2 0 0 2 2 2 0 Unstructured region on MAGI Pkinase PF00069.25 ETS82289.1 - 7.9e-10 38.5 0.0 1.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 ETS82289.1 - 2.6e-09 36.5 0.3 0.1 12.9 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 ETS82289.1 - 1.9e-06 28.0 0.1 3.2e-05 24.0 0.0 2.2 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Pkinase_Tyr PF07714.17 ETS82289.1 - 0.00015 21.1 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 ETS82289.1 - 0.00022 21.6 0.1 0.05 14.0 0.0 3.3 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 ETS82289.1 - 0.00032 21.1 0.0 1.2 9.7 0.1 3.2 2 1 0 2 2 2 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 ETS82289.1 - 0.024 15.2 0.1 5.1 7.8 0.0 2.8 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 ETS82289.1 - 0.21 11.2 0.2 0.78 9.3 0.3 1.8 1 1 1 2 2 2 0 CLASP N terminal FAD_binding_4 PF01565.23 ETS82290.1 - 1.5e-22 79.9 1.3 2.5e-22 79.1 1.3 1.4 1 0 0 1 1 1 1 FAD binding domain GHMP_kinases_N PF00288.26 ETS82291.1 - 2.7e-10 40.3 0.1 5.7e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ETS82291.1 - 6.6e-05 23.2 0.0 0.00019 21.7 0.0 1.7 1 1 0 1 1 1 1 GHMP kinases C terminal 2OG-FeII_Oxy_3 PF13640.6 ETS82292.1 - 3.6e-12 47.0 0.1 9.5e-12 45.7 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_76 PF03663.14 ETS82293.1 - 2e-147 491.5 26.4 2.3e-147 491.3 26.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 ETS82293.1 - 0.058 12.5 15.2 0.17 10.9 0.5 3.2 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 Pyr_redox_2 PF07992.14 ETS82294.1 - 1.9e-48 165.2 1.8 3.1e-48 164.5 1.8 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS82294.1 - 1.3e-15 57.7 1.8 2.4e-11 44.0 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 ETS82294.1 - 6.6e-15 54.8 0.0 1.7e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Reductase_C PF14759.6 ETS82294.1 - 1.5e-06 28.6 0.0 4.2e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.6 ETS82294.1 - 1.6e-06 27.9 0.0 1.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.6 ETS82294.1 - 3.2e-05 23.2 0.1 0.028 13.6 0.0 2.4 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ETS82294.1 - 0.0025 17.8 1.1 0.93 9.5 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding DUF1188 PF06690.11 ETS82294.1 - 0.009 15.6 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) NAD_binding_7 PF13241.6 ETS82294.1 - 0.021 15.3 0.5 0.64 10.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding PALP PF00291.25 ETS82294.1 - 0.064 12.7 0.2 0.4 10.1 0.0 2.2 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme TrkA_N PF02254.18 ETS82294.1 - 0.1 12.9 0.4 23 5.3 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain MFS_1 PF07690.16 ETS82295.1 - 3.6e-43 147.8 24.0 3.6e-43 147.8 24.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily FPP PF05911.11 ETS82296.1 - 2.2e-05 22.9 20.6 0.00041 18.7 20.5 2.0 2 0 0 2 2 2 1 Filament-like plant protein, long coiled-coil Tropomyosin_1 PF12718.7 ETS82296.1 - 0.038 14.2 34.6 0.069 13.3 27.4 3.1 2 1 1 3 3 3 0 Tropomyosin like Fez1 PF06818.15 ETS82296.1 - 0.05 14.0 25.9 3.9 7.9 24.3 2.3 2 0 0 2 2 2 0 Fez1 Fib_alpha PF08702.10 ETS82296.1 - 0.49 10.6 18.2 0.23 11.7 6.0 3.4 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family CHD5 PF04420.14 ETS82296.1 - 3.3 7.6 11.2 0.92 9.4 5.8 2.5 1 1 1 2 2 2 0 CHD5-like protein MAD PF05557.13 ETS82296.1 - 3.4 5.9 33.8 1.1 7.5 27.0 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein SHE3 PF17078.5 ETS82296.1 - 3.9 7.1 29.0 0.058 13.1 4.9 3.3 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 DivIVA PF05103.13 ETS82296.1 - 4.2 7.5 27.1 1 9.5 0.1 3.7 2 1 1 3 3 2 0 DivIVA protein HAP1_N PF04849.13 ETS82296.1 - 5.3 6.1 39.4 0.29 10.3 0.9 3.7 2 1 0 2 2 2 0 HAP1 N-terminal conserved region ATG16 PF08614.11 ETS82296.1 - 6.5 6.9 39.9 3.9 7.6 11.4 3.5 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Bacillus_HBL PF05791.11 ETS82296.1 - 7.1 6.4 10.0 0.58 10.0 1.4 2.5 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Jnk-SapK_ap_N PF09744.9 ETS82296.1 - 8.2 6.6 34.7 1.5 9.0 20.5 3.1 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 XLF PF09302.11 ETS82296.1 - 9.2 6.4 11.0 63 3.7 10.3 2.6 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component zf-C2H2 PF00096.26 ETS82297.1 - 0.00015 22.0 11.4 0.29 11.7 2.1 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS82297.1 - 0.013 16.2 11.0 2.2 9.4 0.8 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3450 PF11932.8 ETS82297.1 - 0.16 11.3 9.4 0.26 10.6 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 ETS82297.1 - 0.27 10.1 8.9 0.4 9.5 8.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1525 PF07511.11 ETS82297.1 - 0.55 10.4 4.6 1.3 9.1 4.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) CENP-F_leu_zip PF10473.9 ETS82297.1 - 0.67 10.0 12.0 0.54 10.3 10.5 1.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SLX9 PF15341.6 ETS82297.1 - 0.9 9.9 8.5 7.4 7.0 7.1 2.6 2 1 0 2 2 2 0 Ribosome biogenesis protein SLX9 Abhydrolase_3 PF07859.13 ETS82299.1 - 3.5e-34 118.5 0.0 5.4e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS82299.1 - 0.00071 20.2 3.4 0.0011 19.7 3.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 ETS82299.1 - 0.0045 15.9 0.0 0.0081 15.1 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 ETS82299.1 - 0.054 13.0 1.6 0.28 10.7 1.6 1.9 1 1 0 1 1 1 0 Esterase PHB depolymerase p450 PF00067.22 ETS82300.1 - 1.5e-33 116.3 0.0 1.9e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CCD48 PF15799.5 ETS82300.1 - 0.0077 14.6 0.4 0.19 10.0 0.3 2.0 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 48 GST_N_3 PF13417.6 ETS82301.1 - 5.3e-17 62.0 0.0 9.6e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ETS82301.1 - 1.8e-11 44.2 0.0 4e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ETS82301.1 - 5.5e-11 42.6 0.0 9.7e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 ETS82301.1 - 1.1e-05 25.5 0.0 5.4e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin GST_C_2 PF13410.6 ETS82301.1 - 0.00016 21.6 0.4 0.00028 20.8 0.4 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ETS82301.1 - 0.16 12.6 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ATP-grasp_3 PF02655.14 ETS82302.1 - 5.3e-07 29.8 0.0 8.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ETS82302.1 - 0.0028 17.2 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.11 ETS82302.1 - 0.0032 17.1 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATPgrasp_YheCD PF14398.6 ETS82302.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 ETS82302.1 - 0.018 14.3 0.0 1.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp MFS_1 PF07690.16 ETS82303.1 - 1.7e-25 89.7 37.4 1.7e-25 89.7 37.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 ETS82303.1 - 0.017 13.5 0.9 0.042 12.1 0.9 1.8 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 ETS82304.1 - 1.5e-31 109.6 32.9 1.5e-31 109.6 32.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily BRI3BP PF14965.6 ETS82304.1 - 0.051 13.1 4.1 0.16 11.5 4.1 1.8 1 0 0 1 1 1 0 Negative regulator of p53/TP53 Rhomboid PF01694.22 ETS82305.1 - 8.8e-35 119.9 10.8 8.8e-35 119.9 10.8 2.0 2 0 0 2 2 2 1 Rhomboid family DUF2177 PF09945.9 ETS82305.1 - 2.3 8.3 6.7 1.6 8.8 0.7 3.0 2 1 1 3 3 3 0 Predicted membrane protein (DUF2177) MFS_1 PF07690.16 ETS82306.1 - 1.2e-38 133.0 38.9 1.4e-38 132.7 38.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS82306.1 - 2.7e-11 43.0 6.1 2.7e-11 43.0 6.1 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 ETS82306.1 - 5.6e-06 25.1 1.4 5.6e-06 25.1 1.4 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) EPSP_synthase PF00275.20 ETS82307.1 - 6.2e-132 440.2 0.0 9e-132 439.7 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 ETS82307.1 - 1.6e-102 342.2 0.0 2.5e-102 341.5 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 ETS82307.1 - 4e-56 190.8 0.0 6.4e-56 190.2 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 ETS82307.1 - 4.8e-36 124.3 0.0 1.9e-34 119.1 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 ETS82307.1 - 1.4e-24 86.2 0.0 3.8e-24 84.7 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 ETS82307.1 - 1.8e-07 31.1 0.0 3.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 ETS82307.1 - 9.9e-05 22.4 0.0 0.00058 19.9 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 ETS82307.1 - 0.0001 22.0 0.0 0.00021 21.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain AAA_16 PF13191.6 ETS82307.1 - 0.058 13.8 0.0 2.5 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain zf-C2H2 PF00096.26 ETS82308.1 - 1.3e-09 38.0 13.7 0.009 16.4 1.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS82308.1 - 0.00011 22.8 10.0 1.3 10.0 1.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ETS82308.1 - 1.8 9.2 8.2 0.64 10.6 0.6 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-Di19 PF05605.12 ETS82308.1 - 2 8.8 5.7 2.3 8.6 1.3 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CENP-T_C PF15511.6 ETS82309.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 ETS82309.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 ETS82309.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 ETS82309.1 - 0.00036 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 ETS82309.1 - 0.00042 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 ETS82309.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ETS82309.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 ETS82309.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 ETS82309.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Histone PF00125.24 ETS82310.1 - 1.6e-51 174.1 2.5 1.8e-51 173.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ETS82310.1 - 8.4e-06 26.1 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 ETS82310.1 - 3.4e-05 24.5 1.0 3.9e-05 24.3 1.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 ETS82310.1 - 3.6e-05 23.8 0.4 6.4e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 ETS82310.1 - 0.0035 17.6 0.3 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ETS82310.1 - 0.028 14.5 0.2 0.046 13.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ETS82310.1 - 0.057 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated RNA_pol_Rpb1_5 PF04998.17 ETS82311.1 - 1.1e-87 293.8 0.1 2.3e-87 292.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 ETS82311.1 - 1.7e-69 233.3 0.2 4.1e-69 232.0 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 ETS82311.1 - 3e-33 115.5 0.1 2e-24 86.5 0.0 2.9 2 1 0 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 ETS82311.1 - 1.3e-29 103.2 0.0 5.8e-29 101.1 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 ETS82311.1 - 1e-16 60.8 0.0 5.4e-16 58.5 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 SVIP PF15811.5 ETS82311.1 - 8.1 7.0 10.1 34 5.0 0.0 3.5 3 0 0 3 3 3 0 Small VCP/p97-interacting protein PRP3 PF08572.10 ETS82312.1 - 3.8e-58 196.9 7.7 3.8e-58 196.9 7.7 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 ETS82312.1 - 1.8e-32 112.5 0.1 1.8e-32 112.5 0.1 2.4 4 0 0 4 4 4 1 Protein of unknown function (DUF1115) GET2 PF08690.10 ETS82312.1 - 0.0065 16.2 3.6 0.0065 16.2 3.6 2.1 2 0 0 2 2 2 1 GET complex subunit GET2 Stm1_N PF09598.10 ETS82312.1 - 0.16 12.8 0.2 0.16 12.8 0.2 3.7 3 0 0 3 3 3 0 Stm1 zf-C2H2 PF00096.26 ETS82313.1 - 6.9e-15 54.6 19.8 4.5e-05 23.7 2.0 3.8 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS82313.1 - 8.1e-10 38.7 17.1 0.0006 20.4 1.5 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ETS82313.1 - 0.0076 16.6 4.6 0.0076 16.6 4.6 4.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ETS82313.1 - 0.01 15.8 0.5 0.01 15.8 0.5 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-BED PF02892.15 ETS82313.1 - 0.091 12.8 10.1 0.048 13.7 6.1 2.2 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.8 ETS82313.1 - 0.095 13.0 9.5 1.7 9.0 1.0 3.9 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 ETS82313.1 - 0.21 11.4 4.9 0.77 9.6 0.6 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 ETS82313.1 - 0.59 10.2 5.8 0.65 10.1 0.4 2.0 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_2 PF12756.7 ETS82313.1 - 1 9.8 8.4 1.8 8.9 6.7 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 ETS82313.1 - 1.4 8.9 6.0 0.53 10.3 2.2 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DEAD_2 PF06733.15 ETS82314.1 - 6.3e-56 188.8 0.3 6.3e-56 188.8 0.3 1.8 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 ETS82314.1 - 2e-47 161.3 3.6 8.4e-43 146.3 1.1 2.8 3 0 0 3 3 3 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 ETS82314.1 - 2.7e-43 148.1 0.5 9.2e-43 146.4 0.0 2.2 3 0 0 3 3 3 1 Helicase C-terminal domain ResIII PF04851.15 ETS82314.1 - 0.00013 22.1 2.7 0.00071 19.6 0.1 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 ETS82314.1 - 0.00078 18.3 0.0 0.0054 15.5 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 ETS82314.1 - 0.0024 17.7 0.0 0.48 10.2 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF2075 PF09848.9 ETS82314.1 - 0.048 12.9 4.6 2.9 7.1 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 ETS82314.1 - 0.11 12.8 1.3 5.3 7.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain MFS_1 PF07690.16 ETS82315.1 - 3.9e-25 88.5 71.4 4.5e-17 62.0 37.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Rossmann-like PF10727.9 ETS82315.1 - 0.0042 16.9 0.9 0.028 14.3 0.2 2.2 2 0 0 2 2 2 1 Rossmann-like domain Cupin_8 PF13621.6 ETS82316.1 - 5.3e-37 127.9 0.0 9.1e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 ETS82316.1 - 3.5e-19 69.5 0.2 9.2e-19 68.1 0.0 1.7 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 ETS82316.1 - 8.8e-09 35.2 0.7 0.00015 21.7 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.6 ETS82316.1 - 3.9e-07 30.2 1.4 0.0039 17.4 0.1 3.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Cupin_4 PF08007.12 ETS82316.1 - 2.3e-05 24.0 0.0 4.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_5 PF13854.6 ETS82316.1 - 0.009 16.0 2.0 29 4.8 0.0 4.0 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.6 ETS82316.1 - 0.036 14.4 1.8 0.64 10.4 0.0 3.2 3 0 0 3 3 3 0 Kelch motif DUF3903 PF13043.6 ETS82316.1 - 0.11 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3903) ANAPC4_WD40 PF12894.7 ETS82317.1 - 3.1e-05 24.2 0.0 0.028 14.7 0.0 3.9 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ETS82317.1 - 0.0013 19.5 2.5 0.48 11.4 0.0 4.2 4 1 0 4 4 4 1 WD domain, G-beta repeat Hira PF07569.11 ETS82317.1 - 0.082 12.6 0.1 0.91 9.2 0.0 2.4 3 0 0 3 3 3 0 TUP1-like enhancer of split DSPc PF00782.20 ETS82318.1 - 1.6e-24 86.3 0.0 1.8e-19 69.9 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ETS82318.1 - 0.0018 17.9 0.0 0.0073 15.9 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 ETS82318.1 - 0.11 12.6 0.0 0.47 10.5 0.1 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate DDHD PF02862.17 ETS82319.1 - 4.9e-24 85.7 0.0 2.5e-14 54.0 0.0 2.8 2 1 0 3 3 3 2 DDHD domain Abhydrolase_6 PF12697.7 ETS82319.1 - 0.019 15.5 0.0 0.067 13.8 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 ETS82319.1 - 0.076 12.6 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Transket_pyr PF02779.24 ETS82320.1 - 1.2e-63 214.0 0.0 2.3e-63 213.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 ETS82320.1 - 3.7e-59 200.1 0.0 5.6e-59 199.5 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 ETS82320.1 - 7.5e-56 188.0 0.0 1.3e-55 187.3 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 ETS82320.1 - 8.6e-20 70.1 1.6 1.8e-19 69.0 1.6 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus YceG_bac PF14266.6 ETS82320.1 - 0.14 11.0 0.1 0.22 10.4 0.1 1.2 1 0 0 1 1 1 0 Putative component of 'biosynthetic module' BSD PF03909.17 ETS82321.1 - 3.8e-27 94.0 5.7 3.2e-13 49.5 0.0 3.3 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 ETS82321.1 - 5.2e-25 87.6 0.0 1.1e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain CysG_dimeriser PF10414.9 ETS82321.1 - 0.27 11.0 5.0 29 4.5 0.1 3.7 3 0 0 3 3 3 0 Sirohaem synthase dimerisation region CLP1_P PF16575.5 ETS82322.1 - 3.9e-34 118.1 0.0 5.9e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 ETS82322.1 - 8.4e-28 97.1 0.0 1.5e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 ETS82322.1 - 4.4e-27 94.1 0.0 7.8e-27 93.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor AAA_24 PF13479.6 ETS82322.1 - 7.1e-05 22.6 0.1 0.00012 21.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 ETS82322.1 - 0.00092 18.7 0.0 0.39 10.1 0.0 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 MMR_HSR1 PF01926.23 ETS82322.1 - 0.00095 19.2 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ETS82322.1 - 0.0022 17.5 0.2 0.0064 16.0 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 ETS82322.1 - 0.0041 16.9 0.1 0.0067 16.2 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 ETS82322.1 - 0.02 14.3 0.0 0.055 12.9 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 ETS82322.1 - 0.026 14.9 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ATP-sulfurylase PF01747.17 ETS82322.1 - 0.083 12.4 0.0 8.9 5.7 0.0 2.2 2 0 0 2 2 2 0 ATP-sulfurylase AAA PF00004.29 ETS82322.1 - 0.099 13.1 0.1 0.2 12.1 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 ETS82322.1 - 0.15 11.7 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 ETS82322.1 - 0.2 11.9 0.0 0.43 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain IPK PF03770.16 ETS82323.1 - 6.6e-50 169.7 0.0 9.2e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase PdxJ PF03740.13 ETS82323.1 - 0.13 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ Arb1 PF09692.10 ETS82324.1 - 1.1e-101 340.9 0.0 1.4e-101 340.6 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Na_H_Exchanger PF00999.21 ETS82325.1 - 9.3e-41 139.9 20.0 1.3e-40 139.4 20.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 ETS82325.1 - 0.025 14.7 0.1 0.15 12.1 0.1 2.4 1 0 0 1 1 1 0 YrhC-like protein Pyr_redox_2 PF07992.14 ETS82326.1 - 4.4e-17 62.2 0.0 1.3e-08 34.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS82326.1 - 0.00037 19.7 0.1 0.02 14.0 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 ETS82326.1 - 0.0013 18.1 0.5 0.0028 17.0 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 ETS82326.1 - 0.016 15.2 1.4 3.3 7.7 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 ETS82326.1 - 0.022 14.0 0.1 0.042 13.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 ETS82326.1 - 0.03 13.6 0.2 2.6 7.2 0.1 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS82326.1 - 0.042 12.5 0.2 0.4 9.3 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 ETS82326.1 - 0.047 13.9 2.7 1.7 8.9 0.1 3.1 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ETS82326.1 - 0.09 11.8 0.1 0.16 11.0 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein muHD PF10291.9 ETS82327.1 - 2.1e-66 224.1 0.0 3.4e-66 223.4 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 ETS82327.1 - 2.3e-07 31.0 0.8 5.4e-07 29.8 0.1 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Cys_Met_Meta_PP PF01053.20 ETS82327.1 - 0.0043 15.7 0.1 0.0095 14.5 0.1 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme BAR_3 PF16746.5 ETS82327.1 - 0.029 14.1 4.7 0.061 13.0 4.7 1.5 1 0 0 1 1 1 0 BAR domain of APPL family XPG_I_2 PF12813.7 ETS82327.1 - 0.056 12.9 2.3 0.11 12.0 2.3 1.5 1 0 0 1 1 1 0 XPG domain containing Muted PF14942.6 ETS82327.1 - 0.13 12.6 6.6 0.051 13.9 3.6 1.9 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Big_4 PF07532.11 ETS82327.1 - 0.48 10.2 2.4 8.1 6.3 0.2 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 4) Vps5 PF09325.10 ETS82327.1 - 1.1 8.8 10.0 0.041 13.4 3.2 2.0 3 0 0 3 3 3 0 Vps5 C terminal like Seryl_tRNA_N PF02403.22 ETS82327.1 - 1.4 9.2 8.6 1.7 8.9 4.3 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.25 ETS82328.1 - 1.1e-33 116.8 0.0 1.7e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS82328.1 - 1.8e-11 43.8 0.0 2.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ASC PF00858.24 ETS82328.1 - 0.087 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Pkinase_fungal PF17667.1 ETS82328.1 - 0.16 10.7 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase NmrA PF05368.13 ETS82329.1 - 3.7e-13 49.6 0.0 8.2e-13 48.4 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS82329.1 - 7.8e-13 48.7 0.0 1.4e-12 47.9 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS82329.1 - 0.0049 16.4 0.0 0.0071 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 ETS82329.1 - 0.08 12.8 0.5 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ETS82329.1 - 0.12 13.0 0.4 0.27 11.9 0.1 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent CoA_binding_2 PF13380.6 ETS82329.1 - 0.13 12.8 0.0 1.9 9.0 0.0 2.3 2 0 0 2 2 2 0 CoA binding domain HD_3 PF13023.6 ETS82331.1 - 2.9e-50 170.4 0.0 3.9e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 ETS82331.1 - 3.5e-08 33.4 0.0 5.8e-08 32.7 0.0 1.3 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme 2-Hacid_dh_C PF02826.19 ETS82332.1 - 1.6e-46 157.9 0.0 2.4e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS82332.1 - 0.00015 21.4 0.0 0.00037 20.2 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 ETS82332.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 ETS82332.1 - 0.063 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain ELFV_dehydrog PF00208.21 ETS82332.1 - 0.14 11.8 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 ETS82332.1 - 0.16 12.4 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 ETS82332.1 - 0.2 11.7 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 ETS82334.1 - 7.2e-17 61.0 0.1 9.9e-16 57.2 0.1 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ETS82334.1 - 4.4e-13 49.2 0.0 5e-12 45.7 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS82334.1 - 4e-12 46.0 0.0 2.1e-10 40.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS82334.1 - 1.2e-09 37.8 0.0 6.7e-07 28.8 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ETS82334.1 - 1.7e-07 31.3 0.6 3.2e-06 27.3 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ETS82334.1 - 9.4e-06 26.1 1.8 0.038 14.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS82334.1 - 0.00013 21.7 3.6 0.00024 20.8 2.4 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 ETS82334.1 - 0.0004 20.5 0.0 0.27 11.3 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 ETS82334.1 - 0.0018 17.6 0.3 0.11 11.8 0.4 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 ETS82334.1 - 0.0058 16.5 0.2 0.01 15.8 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 ETS82334.1 - 0.027 13.2 0.8 0.39 9.4 0.4 2.6 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.24 ETS82334.1 - 0.051 12.7 2.1 0.073 12.1 1.0 1.7 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.19 ETS82334.1 - 0.068 12.5 0.1 3.8 6.8 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ETS82334.1 - 0.079 13.4 0.0 0.59 10.6 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 ETS82334.1 - 0.14 12.2 2.0 0.64 10.0 0.2 2.7 4 0 0 4 4 4 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 ETS82334.1 - 0.19 11.1 0.0 0.34 10.2 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Sas10_Utp3 PF04000.15 ETS82335.1 - 1.1e-17 64.4 1.9 2.8e-17 63.1 1.9 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family EMP70 PF02990.16 ETS82336.1 - 8.1e-206 684.7 6.7 1.2e-205 684.2 6.7 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 AAA PF00004.29 ETS82337.1 - 6.4e-16 59.0 0.0 1e-15 58.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS82337.1 - 0.0036 17.6 0.0 0.0084 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ETS82337.1 - 0.04 13.4 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ETS82337.1 - 0.041 14.3 0.0 0.095 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 ETS82337.1 - 0.08 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 ETS82337.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AFG1_ATPase PF03969.16 ETS82337.1 - 0.15 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase WSC PF01822.19 ETS82338.1 - 3.5e-10 39.9 10.7 8.2e-10 38.7 10.7 1.7 1 0 0 1 1 1 1 WSC domain Abhydrolase_5 PF12695.7 ETS82338.1 - 0.0029 17.4 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 ETS82338.1 - 0.02 15.5 0.4 0.045 14.3 0.2 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 ETS82338.1 - 0.033 14.1 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF981 PF06168.11 ETS82339.1 - 0.66 9.9 11.0 0.22 11.4 1.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF981) Rieske PF00355.26 ETS82340.1 - 4.2e-10 39.4 0.0 8.3e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ETS82340.1 - 0.00021 21.2 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Ribosomal_S21 PF01165.20 ETS82341.1 - 3.5e-15 55.5 3.5 6.2e-15 54.7 3.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 PWI PF01480.17 ETS82342.1 - 1.5e-14 54.0 0.3 3.7e-14 52.8 0.3 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 ETS82342.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ECH_1 PF00378.20 ETS82343.1 - 1.2e-50 172.2 0.0 1.5e-39 135.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ETS82343.1 - 1.1e-23 84.3 0.2 1.8e-22 80.3 0.1 2.4 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase HET PF06985.11 ETS82344.1 - 7e-34 117.3 3.5 1e-33 116.8 0.8 2.5 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 ETS82344.1 - 6.5e-22 77.9 0.0 7.8e-11 42.4 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS82344.1 - 1.6e-13 50.6 0.0 3.5e-09 36.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS82344.1 - 9.5e-10 38.8 0.0 3e-07 30.8 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS82344.1 - 2.8e-08 33.4 0.0 0.0024 18.2 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 ETS82344.1 - 0.00053 20.3 0.0 2.1 8.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat TPR_14 PF13428.6 ETS82344.1 - 0.7 10.9 4.6 1.2 10.2 0.5 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_28 PF00295.17 ETS82345.1 - 3.2e-44 151.3 1.7 4.2e-44 150.9 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 SDH_alpha PF03313.15 ETS82345.1 - 0.19 11.4 0.8 0.38 10.4 0.8 1.4 1 0 0 1 1 1 0 Serine dehydratase alpha chain Glyco_hydro_15 PF00723.21 ETS82347.1 - 1.6e-72 244.8 0.0 8.5e-58 196.2 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 CBM_20 PF00686.19 ETS82347.1 - 4.2e-18 65.0 0.0 9.3e-18 63.9 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain Fringe PF02434.16 ETS82348.1 - 0.019 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Fringe-like SLATT_fungal PF18142.1 ETS82349.1 - 1.4e-26 92.8 0.0 2e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Claudin_2 PF13903.6 ETS82349.1 - 0.021 14.6 0.1 0.03 14.1 0.1 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF1129 PF06570.11 ETS82349.1 - 0.044 13.3 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Nic96 PF04097.14 ETS82349.1 - 0.073 11.5 0.0 0.099 11.1 0.0 1.1 1 0 0 1 1 1 0 Nup93/Nic96 TRM PF02005.16 ETS82350.1 - 1.6e-105 353.4 0.0 3.4e-103 345.7 0.0 2.7 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_25 PF13649.6 ETS82350.1 - 0.00027 21.6 0.0 0.0008 20.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 ETS82350.1 - 0.00036 20.3 0.0 0.00084 19.1 0.0 1.6 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_3 PF01596.17 ETS82350.1 - 0.0014 17.8 0.0 0.0033 16.6 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.14 ETS82350.1 - 0.039 13.5 0.0 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.13 ETS82350.1 - 0.04 13.3 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 ETS82350.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase ATF7IP_BD PF16788.5 ETS82350.1 - 0.76 9.8 6.1 0.37 10.9 3.5 1.7 1 1 1 2 2 2 0 ATF-interacting protein binding domain DAGK_cat PF00781.24 ETS82351.1 - 5.9e-07 29.2 0.0 3.9e-06 26.5 0.0 2.2 1 1 1 2 2 2 1 Diacylglycerol kinase catalytic domain ABC_tran PF00005.27 ETS82352.1 - 7.9e-47 159.2 5.9 2.6e-22 79.8 0.2 3.8 3 1 0 3 3 3 2 ABC transporter SMC_N PF02463.19 ETS82352.1 - 2.1e-09 37.2 2.7 0.056 12.9 0.7 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETS82352.1 - 1.9e-07 31.2 11.1 8.5e-05 22.5 3.1 4.2 3 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ETS82352.1 - 5.4e-07 29.3 1.0 0.001 18.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 ETS82352.1 - 9.3e-07 29.2 1.1 0.00026 21.3 0.2 2.8 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ETS82352.1 - 1.9e-06 28.0 0.2 0.017 15.2 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran_Xtn PF12848.7 ETS82352.1 - 1.8e-05 24.7 6.7 1.8e-05 24.7 6.7 2.6 2 1 0 2 2 2 1 ABC transporter AAA_30 PF13604.6 ETS82352.1 - 1.9e-05 24.4 1.2 0.13 12.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 ETS82352.1 - 5.1e-05 23.3 6.5 0.074 12.9 0.1 3.5 3 0 0 3 3 3 2 RsgA GTPase AAA_33 PF13671.6 ETS82352.1 - 5.6e-05 23.3 0.7 0.025 14.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 ETS82352.1 - 8e-05 22.9 1.1 0.23 11.7 0.0 3.6 4 1 0 4 4 3 1 AAA domain MeaB PF03308.16 ETS82352.1 - 0.00015 20.9 2.0 0.26 10.2 0.1 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 ETS82352.1 - 0.00017 22.0 0.1 0.056 13.9 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ETS82352.1 - 0.00042 20.3 0.1 0.074 13.0 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 ETS82352.1 - 0.00055 20.5 3.1 0.69 10.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 ETS82352.1 - 0.0018 18.7 0.1 0.48 10.8 0.0 2.5 2 0 0 2 2 2 1 RNA helicase DUF87 PF01935.17 ETS82352.1 - 0.0043 17.2 9.9 0.42 10.7 0.6 3.4 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_24 PF13479.6 ETS82352.1 - 0.0056 16.4 0.1 0.24 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 ETS82352.1 - 0.012 15.7 0.8 0.98 9.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 ETS82352.1 - 0.012 14.8 4.0 0.51 9.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 ETS82352.1 - 0.012 15.5 0.1 1.9 8.4 0.0 3.1 3 0 0 3 3 3 0 NTPase ABC_ATPase PF09818.9 ETS82352.1 - 0.012 14.4 0.3 0.061 12.1 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_7 PF12775.7 ETS82352.1 - 0.012 15.1 0.2 0.3 10.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 ETS82352.1 - 0.015 15.7 8.4 0.47 10.8 3.2 3.2 3 1 0 3 3 2 0 AAA ATPase domain AAA_23 PF13476.6 ETS82352.1 - 0.017 15.7 22.5 0.24 11.9 7.2 3.6 3 1 0 3 3 3 0 AAA domain AAA_15 PF13175.6 ETS82352.1 - 0.018 14.8 8.2 0.059 13.1 0.0 3.1 3 1 1 4 4 4 0 AAA ATPase domain MobB PF03205.14 ETS82352.1 - 0.03 14.2 0.2 15 5.5 0.0 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NYN PF01936.18 ETS82352.1 - 0.032 14.7 0.0 0.074 13.5 0.0 1.7 1 0 0 1 1 1 0 NYN domain Zeta_toxin PF06414.12 ETS82352.1 - 0.034 13.4 0.1 7.3 5.8 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_27 PF13514.6 ETS82352.1 - 0.046 13.3 0.0 0.046 13.3 0.0 2.8 4 0 0 4 4 3 0 AAA domain Dynamin_N PF00350.23 ETS82352.1 - 0.066 13.3 3.2 0.46 10.5 0.1 3.0 3 0 0 3 3 3 0 Dynamin family AAA_5 PF07728.14 ETS82352.1 - 0.068 13.2 0.2 0.72 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Arf PF00025.21 ETS82352.1 - 0.087 12.3 0.8 1.8 8.0 0.2 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family SbcCD_C PF13558.6 ETS82352.1 - 0.092 13.0 0.0 11 6.4 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Phage_30_3 PF08010.11 ETS82352.1 - 0.11 12.3 0.7 0.33 10.8 0.1 2.1 2 1 0 2 2 1 0 Bacteriophage protein GP30.3 ATP-synt_ab PF00006.25 ETS82352.1 - 0.12 12.1 0.1 6.9 6.3 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 ETS82352.1 - 0.22 10.6 6.4 1.3 8.1 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain AAA_17 PF13207.6 ETS82352.1 - 0.23 11.9 10.1 2.8 8.4 0.2 3.9 3 1 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 ETS82352.1 - 0.25 11.2 2.4 1.8 8.4 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 ETS82352.1 - 0.9 8.7 3.8 2.4 7.3 0.0 2.7 2 1 0 2 2 2 0 KAP family P-loop domain Roc PF08477.13 ETS82352.1 - 1 9.6 3.6 8.3 6.7 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Thymidylate_kin PF02223.17 ETS82352.1 - 1.4 8.5 8.2 18 5.0 0.0 3.3 3 0 0 3 3 3 0 Thymidylate kinase SET PF00856.28 ETS82353.1 - 1.1e-11 45.4 1.0 4.9e-11 43.3 0.2 2.3 2 1 0 2 2 2 1 SET domain SAF PF08666.12 ETS82353.1 - 0.079 13.6 0.0 1.3 9.7 0.0 2.4 2 0 0 2 2 2 0 SAF domain TPR_8 PF13181.6 ETS82353.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Sugar_tr PF00083.24 ETS82354.1 - 1.5e-119 399.9 31.3 1.7e-119 399.7 31.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS82354.1 - 8.1e-22 77.6 36.2 8.1e-22 77.6 36.2 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS82354.1 - 0.00045 18.8 3.0 0.00045 18.8 3.0 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Cupin_1 PF00190.22 ETS82355.1 - 1.7e-20 73.2 1.3 2.9e-20 72.4 1.3 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 ETS82355.1 - 0.0094 15.6 0.1 0.058 13.1 0.1 2.0 1 1 0 1 1 1 1 Cupin domain SUN PF03856.13 ETS82356.1 - 2.8e-75 252.9 7.3 5e-75 252.1 7.3 1.4 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) PCI PF01399.27 ETS82357.1 - 0.017 15.7 0.0 11 6.6 0.0 2.6 2 0 0 2 2 2 0 PCI domain TPR_2 PF07719.17 ETS82357.1 - 0.02 15.0 0.0 0.059 13.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat MFS_1 PF07690.16 ETS82358.1 - 2.1e-43 148.6 32.6 2.1e-43 148.6 32.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS82358.1 - 2.6e-11 42.7 3.7 4.2e-11 42.0 3.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS82358.1 - 7.6e-10 38.2 24.3 2.2e-09 36.7 24.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 ETS82358.1 - 0.00029 20.2 5.4 0.00029 20.2 5.4 2.3 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF3611 PF12263.8 ETS82358.1 - 4.2 7.2 8.4 1.4 8.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) Thiolase_N PF00108.23 ETS82359.1 - 1.9e-89 299.5 0.4 3e-89 298.8 0.4 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ETS82359.1 - 6e-37 126.0 0.7 6e-37 126.0 0.7 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ETS82359.1 - 0.00011 21.9 0.5 0.00026 20.7 0.2 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_23 PF13489.6 ETS82360.1 - 5.7e-12 45.8 0.0 9.1e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS82360.1 - 2.7e-06 27.3 0.1 1.3e-05 25.0 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS82360.1 - 3.8e-06 27.5 0.0 7.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS82360.1 - 0.046 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain UQ_con PF00179.26 ETS82361.1 - 6.9e-52 174.8 0.1 7.8e-52 174.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ETS82361.1 - 0.00057 19.6 0.0 0.00064 19.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ETS82361.1 - 0.061 13.6 0.0 0.081 13.2 0.0 1.4 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.23 ETS82362.1 - 9.8e-111 369.9 0.3 9.8e-111 369.9 0.3 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ETS82362.1 - 6.5e-26 91.1 0.1 3.5e-25 88.7 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding DUF4404 PF14357.6 ETS82362.1 - 0.12 13.0 0.1 0.12 13.0 0.1 6.7 2 2 5 7 7 7 0 Domain of unknown function (DUF4404) RolB_RolC PF02027.17 ETS82362.1 - 0.63 9.7 2.5 2.4 7.8 0.1 2.6 2 0 0 2 2 2 0 RolB/RolC glucosidase family TFIID-18kDa PF02269.16 ETS82363.1 - 5.2e-30 103.3 1.0 3.7e-29 100.6 0.1 2.5 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit Myc_N PF01056.18 ETS82363.1 - 0.0058 16.6 0.2 0.009 16.0 0.2 1.3 1 0 0 1 1 1 1 Myc amino-terminal region Ribosomal_60s PF00428.19 ETS82363.1 - 0.84 10.3 5.0 1.5 9.4 0.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein LCM PF04072.14 ETS82364.1 - 6.6e-22 78.4 0.0 2.7e-21 76.4 0.0 2.1 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase UPF0259 PF06790.11 ETS82365.1 - 0.052 13.3 0.2 0.052 13.3 0.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0259) Gemini_mov PF01708.16 ETS82365.1 - 2 8.3 12.7 0.18 11.6 0.6 3.2 3 0 0 3 3 3 0 Geminivirus putative movement protein ArAE_2_N PF10337.9 ETS82366.1 - 2.2e-19 69.9 5.3 5.6e-15 55.3 0.1 3.6 3 1 1 4 4 4 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 ETS82366.1 - 3.1e-11 43.5 13.7 3.1e-11 43.5 13.7 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 ETS82366.1 - 4.1e-09 35.8 11.0 4.1e-09 35.8 11.0 3.9 4 1 1 5 5 5 1 Aluminium activated malate transporter ArAE_2 PF10334.9 ETS82366.1 - 3.5e-05 23.7 0.1 6.7e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 NAM-associated PF14303.6 ETS82366.1 - 0.0037 18.0 0.6 0.0037 18.0 0.6 3.4 3 0 0 3 3 3 1 No apical meristem-associated C-terminal domain CCDC106 PF15794.5 ETS82366.1 - 0.84 9.3 5.8 2.4 7.8 5.8 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Sigma70_ner PF04546.13 ETS82366.1 - 0.93 9.3 6.7 1.8 8.4 1.2 3.0 3 0 0 3 3 3 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.12 ETS82366.1 - 3.2 7.4 20.2 0.55 9.9 3.8 2.7 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein SpoIIIAH PF12685.7 ETS82366.1 - 7.3 6.3 10.0 2 8.2 2.6 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein Ist1 PF03398.14 ETS82367.1 - 2.6e-63 212.8 1.6 3.3e-63 212.5 1.6 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway zf-CCHC_2 PF13696.6 ETS82368.1 - 4.1e-09 36.1 18.7 3.4e-06 26.8 6.6 2.9 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_3 PF13917.6 ETS82368.1 - 0.065 13.2 0.4 0.065 13.2 0.4 2.8 2 0 0 2 2 2 0 Zinc knuckle DUF4400 PF14348.6 ETS82368.1 - 0.22 11.0 0.1 0.44 10.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Clat_adaptor_s PF01217.20 ETS82369.1 - 3.3e-43 147.0 2.6 4e-43 146.8 2.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain adh_short PF00106.25 ETS82370.1 - 8.6e-22 77.5 0.0 8.8e-15 54.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS82370.1 - 6.8e-11 42.2 0.1 7.7e-10 38.7 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS82370.1 - 7.4e-06 26.0 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 ETS82371.1 - 9.9e-40 136.5 28.1 9.9e-40 136.5 28.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 ETS82371.1 - 0.0069 14.7 9.1 0.012 13.9 7.3 2.2 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Phage_holin_2_4 PF16082.5 ETS82371.1 - 0.47 10.2 7.6 0.29 10.9 0.5 3.4 2 1 1 3 3 3 0 Bacteriophage holin family, superfamily II-like Fungal_trans PF04082.18 ETS82372.1 - 1.6e-16 60.1 0.0 2.7e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HHH_3 PF12836.7 ETS82372.1 - 0.07 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif FAA_hydrolase PF01557.18 ETS82373.1 - 6.9e-65 218.8 0.0 8.3e-65 218.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Clr2_transil PF16761.5 ETS82374.1 - 7e-17 62.0 0.4 1.5e-16 61.0 0.4 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 ETS82374.1 - 1.1e-10 42.5 1.7 3.6e-10 40.8 0.0 2.6 2 1 0 3 3 3 1 Transcription-silencing protein Clr2 Lipase_GDSL PF00657.22 ETS82374.1 - 0.085 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase TFIIA PF03153.13 ETS82374.1 - 0.66 9.9 5.2 1.1 9.2 5.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_RNApol_7kD PF03604.13 ETS82375.1 - 0.0069 16.0 2.2 0.0069 16.0 2.2 4.7 4 2 0 4 4 4 1 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_15 PF17032.5 ETS82375.1 - 0.01 16.6 3.6 0.01 16.6 3.6 4.0 3 1 1 4 4 4 0 zinc-ribbon family FYVE_2 PF02318.16 ETS82375.1 - 0.023 14.9 27.8 0.94 9.7 4.8 3.2 3 0 0 3 3 3 0 FYVE-type zinc finger IBR PF01485.21 ETS82375.1 - 0.19 12.0 37.5 0.089 13.0 5.6 3.8 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain zf-CHY PF05495.12 ETS82375.1 - 1.6 9.3 35.8 0.37 11.3 5.4 3.6 3 1 0 3 3 3 0 CHY zinc finger Sar8_2 PF03058.14 ETS82375.1 - 2.6 8.7 11.5 1.2 9.8 0.1 3.1 3 0 0 3 3 3 0 Sar8.2 family DAO PF01266.24 ETS82376.1 - 7.8e-37 127.7 0.0 9e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS82376.1 - 0.00057 20.1 0.1 0.0017 18.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ETS82376.1 - 0.0029 16.9 0.1 0.0029 16.9 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 ETS82376.1 - 0.014 16.0 0.1 0.072 13.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS82376.1 - 0.032 13.3 0.0 0.077 12.1 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain ALG3 PF05208.13 ETS82377.1 - 1.1e-147 492.2 18.3 1.3e-147 492.0 18.3 1.0 1 0 0 1 1 1 1 ALG3 protein MacB_PCD PF12704.7 ETS82377.1 - 0.05 13.9 0.1 0.1 13.0 0.1 1.5 1 0 0 1 1 1 0 MacB-like periplasmic core domain eIF-1a PF01176.19 ETS82378.1 - 4.3e-20 71.3 0.1 6e-20 70.8 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RGS PF00615.19 ETS82379.1 - 3.5e-35 120.8 0.0 1.1e-34 119.3 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 ETS82379.1 - 5.2e-21 74.5 0.0 8e-18 64.3 0.0 3.3 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Replic_Relax PF13814.6 ETS82379.1 - 0.13 12.3 0.0 2.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Replication-relaxation CAP_N PF01213.19 ETS82380.1 - 1.2 8.6 5.6 1.9 7.9 5.6 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Presenilin PF01080.17 ETS82381.1 - 7.4 5.2 5.2 10 4.8 5.2 1.2 1 0 0 1 1 1 0 Presenilin ORC4_C PF14629.6 ETS82382.1 - 3.1e-69 232.7 0.0 5.2e-69 231.9 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 ETS82382.1 - 4.3e-11 43.5 0.0 1.1e-10 42.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PHD PF00628.29 ETS82382.1 - 5.5e-11 42.2 7.4 9.8e-11 41.4 7.4 1.4 1 0 0 1 1 1 1 PHD-finger AAA_22 PF13401.6 ETS82382.1 - 7.8e-08 32.7 0.3 2.5e-07 31.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 ETS82382.1 - 8.9e-08 32.6 0.0 2.3e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PHD_2 PF13831.6 ETS82382.1 - 4.9e-07 29.2 2.1 9.4e-07 28.3 2.1 1.5 1 0 0 1 1 1 1 PHD-finger NACHT PF05729.12 ETS82382.1 - 6.4e-05 22.9 0.0 0.00035 20.5 0.0 2.1 1 1 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 ETS82382.1 - 0.0012 18.2 0.0 0.0024 17.2 0.0 1.5 1 0 0 1 1 1 1 KAP family P-loop domain AAA_14 PF13173.6 ETS82382.1 - 0.0016 18.5 0.0 0.0034 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain C1_1 PF00130.22 ETS82382.1 - 0.0045 16.8 0.4 0.0045 16.8 0.4 1.7 2 0 0 2 2 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TniB PF05621.11 ETS82382.1 - 0.008 15.6 0.1 4 6.8 0.0 2.3 2 0 0 2 2 2 2 Bacterial TniB protein AAA_30 PF13604.6 ETS82382.1 - 0.0082 15.9 0.1 0.017 14.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ETS82382.1 - 0.0092 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 ETS82382.1 - 0.0096 16.3 0.1 0.022 15.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 ETS82382.1 - 0.011 14.9 0.1 0.024 13.8 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain ATP-synt_ab PF00006.25 ETS82382.1 - 0.011 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 ETS82382.1 - 0.015 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 ETS82382.1 - 0.022 13.9 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Prok-RING_1 PF14446.6 ETS82382.1 - 0.024 14.6 3.2 0.054 13.4 3.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 RNA_helicase PF00910.22 ETS82382.1 - 0.1 13.0 0.0 0.35 11.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase ORC2 PF04084.14 ETS82382.1 - 0.13 11.1 0.4 7.5 5.4 0.0 2.3 2 0 0 2 2 2 0 Origin recognition complex subunit 2 Zf_RING PF16744.5 ETS82382.1 - 0.21 11.7 6.3 0.078 13.1 3.3 1.8 1 1 0 1 1 1 0 KIAA1045 RING finger FYVE_2 PF02318.16 ETS82382.1 - 0.34 11.1 2.7 0.88 9.8 2.7 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger ADK_lid PF05191.14 ETS82382.1 - 0.8 9.7 3.1 2.9 7.9 3.1 2.0 1 0 0 1 1 1 0 Adenylate kinase, active site lid C1_2 PF03107.16 ETS82382.1 - 0.81 10.0 3.0 1.9 8.9 3.0 1.6 1 0 0 1 1 1 0 C1 domain zf-RING_2 PF13639.6 ETS82382.1 - 2.2 8.7 6.9 24 5.4 7.3 2.2 1 1 1 2 2 2 0 Ring finger domain Pkinase PF00069.25 ETS82383.1 - 3.7e-60 203.5 0.0 1.8e-59 201.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS82383.1 - 4.4e-35 121.2 0.0 7.3e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 ETS82383.1 - 9.3e-25 86.5 16.6 6.4e-13 48.6 4.4 2.7 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 ETS82383.1 - 2e-19 69.2 30.7 6.3e-12 45.2 10.0 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 ETS82383.1 - 4.1e-14 53.0 0.9 1.8e-13 50.9 0.9 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 ETS82383.1 - 8.7e-05 22.8 0.1 0.00016 21.9 0.1 1.4 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 ETS82383.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like She9_MDM33 PF05546.11 ETS82384.1 - 1.8e-78 262.9 1.8 2.8e-78 262.3 1.8 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family LemA PF04011.12 ETS82384.1 - 0.02 14.8 0.2 0.063 13.1 0.1 2.0 2 0 0 2 2 2 0 LemA family ZapB PF06005.12 ETS82384.1 - 0.027 14.9 0.3 0.027 14.9 0.3 2.7 3 0 0 3 3 3 0 Cell division protein ZapB ABC_tran_CTD PF16326.5 ETS82384.1 - 0.027 14.7 0.8 0.027 14.7 0.8 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain Golgin_A5 PF09787.9 ETS82384.1 - 0.063 12.7 0.5 0.11 12.0 0.5 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 PsbH PF00737.20 ETS82384.1 - 0.43 10.4 1.3 0.85 9.4 1.3 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein HAD PF12710.7 ETS82385.1 - 2.9e-23 83.3 0.0 4.2e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 ETS82385.1 - 0.016 14.7 0.0 0.35 10.2 0.0 2.1 2 0 0 2 2 2 0 Putative Phosphatase Hydrolase PF00702.26 ETS82385.1 - 0.049 13.9 1.9 1.5 9.1 0.0 3.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 ETS82385.1 - 0.05 13.1 0.1 0.21 11.1 0.0 1.9 2 1 1 3 3 3 0 Pyrimidine 5'-nucleotidase (UMPH-1) CDC73_C PF05179.14 ETS82386.1 - 5.4e-55 185.4 0.0 8.6e-55 184.7 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal TAP42 PF04177.12 ETS82387.1 - 3.3e-105 351.8 1.6 3.7e-105 351.6 1.6 1.0 1 0 0 1 1 1 1 TAP42-like family Ribonuclease_3 PF00636.26 ETS82388.1 - 1.2e-40 138.4 0.0 7.5e-20 71.5 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 ETS82388.1 - 7.4e-24 84.3 0.0 4.3e-09 36.6 0.0 4.4 3 1 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 ETS82388.1 - 6.3e-21 74.4 0.1 2.5e-20 72.4 0.1 2.2 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 ETS82388.1 - 1.2e-17 64.2 0.1 1.3e-16 60.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS82388.1 - 1.3e-14 54.5 0.0 3e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ETS82388.1 - 5.7e-11 42.5 0.0 1.1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ETS82388.1 - 0.00095 19.5 0.2 0.0041 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF777 PF05606.11 ETS82388.1 - 0.083 12.6 0.1 0.91 9.3 0.0 2.5 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF777) CLASP_N PF12348.8 ETS82390.1 - 4.2e-125 415.8 1.7 4.7e-87 291.3 0.0 3.1 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 ETS82390.1 - 0.0015 18.6 0.1 1.8 9.0 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 ETS82390.1 - 0.0016 18.5 0.0 3.3 7.7 0.0 3.5 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ETS82390.1 - 0.0087 16.4 1.4 12 6.3 0.0 5.2 4 1 2 6 6 6 1 HEAT repeats SAPS PF04499.15 ETS82390.1 - 0.099 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2999 PF11212.8 ETS82390.1 - 0.15 12.4 0.0 0.78 10.1 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2999) BSP PF04450.12 ETS82391.1 - 3.5e-69 232.8 0.0 4.3e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Alpha-amylase_C PF02806.18 ETS82393.1 - 0.051 14.1 0.1 0.057 13.9 0.1 1.1 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain Iso_dh PF00180.20 ETS82394.1 - 8.9e-102 340.8 0.0 1e-101 340.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 ETS82394.1 - 0.015 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 Sec5 PF15469.6 ETS82395.1 - 4.1e-39 134.3 0.0 9.9e-39 133.1 0.0 1.7 1 1 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 ETS82395.1 - 0.00025 21.1 0.2 0.0014 18.6 0.2 2.4 1 0 0 1 1 1 1 Vps51/Vps67 Zn_clus PF00172.18 ETS82397.1 - 0.092 12.9 7.6 0.2 11.8 7.6 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-BED PF02892.15 ETS82397.1 - 2.7 8.1 5.4 0.52 10.4 0.3 2.2 2 0 0 2 2 2 0 BED zinc finger Glyco_hydro_92 PF07971.12 ETS82398.1 - 6.6e-139 463.8 3.1 8.1e-139 463.5 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 ETS82398.1 - 2.1e-49 168.6 6.1 3.1e-49 168.1 6.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Fungal_trans PF04082.18 ETS82399.1 - 2.1e-14 53.2 0.0 5.5e-14 51.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS82399.1 - 2.6e-07 30.6 11.5 4.6e-07 29.8 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 ETS82400.1 - 3e-19 69.3 0.0 1.2e-17 64.0 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS82400.1 - 3e-07 30.3 0.0 5.6e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ETS82400.1 - 0.0002 20.9 0.0 0.00037 20.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS82400.1 - 0.0014 18.1 0.1 0.003 17.0 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 ETS82400.1 - 0.0052 16.7 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ETS82400.1 - 0.0058 16.5 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ETS82400.1 - 0.066 12.3 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4879 PF16219.5 ETS82400.1 - 0.11 12.7 0.1 6.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4879) Abhydrolase_1 PF00561.20 ETS82401.1 - 2.9e-08 33.7 0.2 2.6e-07 30.6 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS82401.1 - 0.00045 19.5 0.0 0.15 11.3 0.0 3.1 2 1 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 ETS82401.1 - 0.01 15.4 0.1 2.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Phosphorylase PF00343.20 ETS82402.1 - 0 1057.4 0.1 0 1057.2 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase G-alpha PF00503.20 ETS82403.1 - 3e-108 362.1 0.0 3.5e-108 361.9 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ETS82403.1 - 5.5e-11 42.2 0.3 8.2e-10 38.4 0.2 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family SH3_2 PF07653.17 ETS82404.1 - 0.0018 17.9 0.1 0.0035 17.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ETS82404.1 - 0.33 10.6 2.6 0.64 9.7 2.6 1.5 1 0 0 1 1 1 0 SH3 domain Pex2_Pex12 PF04757.14 ETS82405.1 - 1.3e-53 181.9 1.1 1.7e-53 181.5 1.1 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 ETS82405.1 - 0.001 18.8 2.4 0.0017 18.1 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS82405.1 - 0.0013 18.5 1.7 0.0024 17.7 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ETS82405.1 - 0.0017 18.5 2.2 0.0028 17.8 2.2 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 ETS82405.1 - 0.0039 17.5 3.0 0.0065 16.8 3.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ETS82405.1 - 0.14 12.1 3.1 0.25 11.3 3.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS82405.1 - 0.25 11.4 2.1 0.47 10.5 2.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zinc-ribbons_6 PF07191.12 ETS82405.1 - 0.3 11.1 2.2 0.52 10.3 2.2 1.3 1 0 0 1 1 1 0 zinc-ribbons Glycos_transf_2 PF00535.26 ETS82406.1 - 2.3e-26 92.6 0.0 4.2e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ETS82406.1 - 1.3e-09 38.3 0.0 4.2e-06 26.8 0.0 2.9 2 1 1 3 3 3 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ETS82406.1 - 2.8e-05 23.8 0.0 0.00012 21.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 ETS82406.1 - 0.02 15.4 0.0 0.043 14.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 SE PF08491.10 ETS82407.1 - 6.1e-90 301.0 0.0 7.6e-90 300.7 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 ETS82407.1 - 7.4e-10 38.6 0.0 8.3e-05 22.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 ETS82407.1 - 8.7e-09 35.4 0.1 2.2e-07 30.8 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 ETS82407.1 - 3e-06 26.7 0.0 5.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 ETS82407.1 - 3.4e-06 27.2 0.2 7.6e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ETS82407.1 - 1.8e-05 24.3 1.6 8.7e-05 22.0 1.6 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ETS82407.1 - 4.1e-05 22.8 0.0 0.00041 19.5 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ETS82407.1 - 0.00012 21.3 0.4 0.00021 20.5 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS82407.1 - 0.0046 16.2 0.0 0.0083 15.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS82407.1 - 0.011 14.4 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 ETS82407.1 - 0.019 14.6 0.1 0.032 13.9 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 ETS82407.1 - 0.032 14.8 0.1 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ETS82407.1 - 0.054 13.6 0.0 0.09 12.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 ETS82407.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 ETS82407.1 - 0.15 11.0 0.1 0.47 9.5 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 ETS82407.1 - 0.24 10.2 0.1 1.9 7.3 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase Mito_carr PF00153.27 ETS82409.1 - 2.9e-60 200.2 1.7 3.9e-20 71.6 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S24 PF00717.23 ETS82410.1 - 2.2e-05 24.3 0.1 0.00012 21.9 0.1 2.0 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 ETS82410.1 - 0.036 13.9 0.0 1.6 8.5 0.0 2.3 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 Glyco_transf_15 PF01793.16 ETS82411.1 - 1.5e-133 445.1 6.2 1.8e-133 444.8 6.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PAT1 PF09770.9 ETS82412.1 - 0 1197.2 7.0 0 1197.0 7.0 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Sin_N PF04801.13 ETS82413.1 - 2.5e-22 79.7 0.0 5e-22 78.7 0.0 1.5 1 1 0 1 1 1 1 Sin-like protein conserved region RNA_pol_I_A49 PF06870.12 ETS82413.1 - 0.052 12.4 0.5 0.35 9.7 0.0 2.0 2 0 0 2 2 2 0 A49-like RNA polymerase I associated factor SH3_2 PF07653.17 ETS82414.1 - 0.00021 20.9 1.1 0.027 14.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 ETS82414.1 - 0.00034 20.4 0.7 0.61 10.0 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain HET PF06985.11 ETS82415.1 - 8.6e-29 100.8 0.0 2e-28 99.6 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FA_desaturase PF00487.24 ETS82416.1 - 7.5e-10 39.1 30.8 7.9e-10 39.0 29.9 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DHH PF01368.20 ETS82417.1 - 0.0034 17.6 0.2 0.0058 16.8 0.2 1.4 1 0 0 1 1 1 1 DHH family Abhydrolase_1 PF00561.20 ETS82418.1 - 2.6e-21 76.4 0.0 1.1e-17 64.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 ETS82418.1 - 2.8e-17 62.7 0.0 8.2e-17 61.2 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Stomagen PF16851.5 ETS82418.1 - 0.1 12.7 0.4 0.44 10.6 0.1 2.1 2 0 0 2 2 2 0 Stomagen Rax2 PF12768.7 ETS82420.1 - 0.014 14.9 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TMEM132D_C PF15706.5 ETS82420.1 - 0.023 14.5 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term PROL5-SMR PF15621.6 ETS82420.1 - 0.086 13.4 4.1 0.13 12.8 4.1 1.3 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family TMEM100 PF16311.5 ETS82420.1 - 0.12 12.0 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 100 2-Hacid_dh_C PF02826.19 ETS82421.1 - 1.1e-44 151.9 0.0 1.4e-29 102.7 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ETS82421.1 - 0.0056 16.0 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 ETS82422.1 - 1.8e-30 106.0 28.0 1.8e-30 106.0 28.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS82422.1 - 1.1e-13 50.9 13.0 1.1e-13 50.9 13.0 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 ETS82422.1 - 1.6e-05 23.5 5.2 1.6e-05 23.5 5.2 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF3593 PF12159.8 ETS82422.1 - 0.025 14.6 0.5 0.11 12.5 0.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) Pectinesterase PF01095.19 ETS82423.1 - 3.7e-26 91.5 0.1 3.9e-22 78.3 0.5 2.1 2 0 0 2 2 2 2 Pectinesterase Bac_rhodopsin PF01036.18 ETS82424.1 - 1.6e-48 165.2 19.1 2e-48 164.9 19.1 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein MerC PF03203.14 ETS82424.1 - 0.033 14.6 10.1 0.061 13.8 2.2 2.3 2 0 0 2 2 2 0 MerC mercury resistance protein TMEM208_SND2 PF05620.11 ETS82424.1 - 0.068 12.9 4.7 0.079 12.7 0.2 2.5 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 SUR7 PF06687.12 ETS82424.1 - 0.21 11.2 8.0 0.61 9.7 2.0 2.2 1 1 0 2 2 2 0 SUR7/PalI family DUF1772 PF08592.11 ETS82424.1 - 0.31 11.3 10.8 1.6 9.0 1.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF3810 PF12725.7 ETS82424.1 - 6 6.1 8.7 5.1 6.3 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) ANAPC4_WD40 PF12894.7 ETS82425.1 - 1.2e-18 67.1 0.3 0.0028 17.9 0.0 8.3 5 3 0 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ETS82425.1 - 1.1e-16 60.9 17.5 0.00037 21.2 0.0 8.9 10 0 0 10 10 7 3 WD domain, G-beta repeat PD40 PF07676.12 ETS82425.1 - 8.6e-09 35.1 1.2 2.5 8.2 0.0 7.0 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat NACHT PF05729.12 ETS82425.1 - 1.2e-08 35.0 0.0 3.2e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 ETS82425.1 - 2.8e-05 23.3 0.1 4.9 6.0 0.0 5.2 5 1 1 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 ETS82425.1 - 0.00022 21.6 0.2 0.0035 17.7 0.0 2.9 2 1 2 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 ETS82425.1 - 0.0004 20.7 0.1 0.006 16.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Nbas_N PF15492.6 ETS82425.1 - 0.0017 17.7 0.3 3.8 6.8 0.0 4.3 3 2 2 5 5 5 1 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.6 ETS82425.1 - 0.0027 17.3 0.0 0.013 15.1 0.0 2.2 1 0 0 1 1 1 1 PQQ-like domain eIF2A PF08662.11 ETS82425.1 - 0.0097 15.8 0.0 1.7 8.5 0.0 3.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 ETS82425.1 - 0.058 13.1 0.0 7.4 6.2 0.0 3.2 4 0 0 4 4 4 0 Lipoprotein LpqB beta-propeller domain AAA PF00004.29 ETS82425.1 - 0.081 13.3 0.0 0.25 11.7 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 ETS82425.1 - 0.16 12.3 0.0 0.67 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain US22 PF02393.16 ETS82425.1 - 0.2 11.9 0.2 0.5 10.6 0.2 1.7 1 0 0 1 1 1 0 US22 like DUF2075 PF09848.9 ETS82425.1 - 0.22 10.7 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SH3_9 PF14604.6 ETS82427.1 - 4.6e-09 36.0 0.0 7.9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ETS82427.1 - 0.0005 19.6 0.0 0.00076 19.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ETS82427.1 - 0.0018 17.9 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Amnionless PF14828.6 ETS82427.1 - 0.066 12.0 0.5 0.094 11.5 0.5 1.2 1 0 0 1 1 1 0 Amnionless Macoilin PF09726.9 ETS82427.1 - 0.36 9.3 1.6 0.5 8.9 1.6 1.2 1 0 0 1 1 1 0 Macoilin family Fungal_trans PF04082.18 ETS82428.1 - 5.7e-07 28.8 0.7 1.5e-06 27.4 0.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS82428.1 - 2.5e-05 24.3 11.4 5e-05 23.3 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.13 ETS82429.1 - 1.1e-06 29.1 0.0 1.7e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 ETS82429.1 - 0.00044 19.1 0.0 0.77 8.5 0.0 2.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) Sugar_tr PF00083.24 ETS82430.1 - 1.4e-96 324.2 23.8 1.6e-96 324.0 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS82430.1 - 6.1e-27 94.5 34.7 1.2e-19 70.4 12.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.13 ETS82430.1 - 0.0009 19.5 18.5 0.38 11.1 2.8 4.7 5 0 0 5 5 5 3 Transglycosylase associated protein Pyr_redox_2 PF07992.14 ETS82431.1 - 6.6e-23 81.4 0.0 1.1e-22 80.7 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS82431.1 - 1.4e-07 30.5 0.0 0.00029 19.7 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 ETS82431.1 - 2.6e-06 26.9 0.1 0.083 12.1 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS82431.1 - 7.2e-05 22.0 0.1 0.0011 18.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 ETS82431.1 - 0.0003 20.0 0.0 0.0051 15.9 0.0 2.4 1 1 1 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ETS82431.1 - 0.00053 20.2 0.0 0.00096 19.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS82431.1 - 0.0019 18.2 0.4 1.9 8.5 0.0 2.5 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_oxidored PF12831.7 ETS82431.1 - 0.002 17.5 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ETS82431.1 - 0.0083 15.4 0.0 0.018 14.3 0.0 1.5 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 ETS82431.1 - 0.016 14.8 1.1 0.28 10.7 1.1 2.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 ETS82431.1 - 0.04 13.1 0.0 2.1 7.4 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Cytochrom_C PF00034.21 ETS82431.1 - 0.11 13.6 0.0 0.24 12.6 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c YscJ_FliF PF01514.17 ETS82431.1 - 0.19 11.4 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family NUC130_3NT PF08158.12 ETS82431.1 - 0.2 12.0 0.0 0.48 10.8 0.0 1.7 1 0 0 1 1 1 0 NUC130/3NT domain Sugar_tr PF00083.24 ETS82432.1 - 2.1e-90 303.7 28.6 2.6e-90 303.5 28.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS82432.1 - 1.2e-09 37.6 51.3 3.1e-06 26.3 23.5 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily ADH_N PF08240.12 ETS82433.1 - 3.2e-16 59.2 1.2 1.4e-15 57.1 0.1 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS82433.1 - 1.3e-10 41.4 0.1 2.4e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ribonuc_L-PSP PF01042.21 ETS82434.1 - 1.7e-22 79.7 0.0 2e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fungal_trans PF04082.18 ETS82435.1 - 3.5e-09 36.1 0.0 5.5e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS82435.1 - 0.025 14.7 5.0 0.045 13.9 5.0 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 ETS82438.1 - 3.4e-65 219.5 11.9 3.4e-65 219.5 11.9 2.0 1 1 1 2 2 2 1 RTA1 like protein DUF2206 PF09971.9 ETS82438.1 - 0.018 13.9 2.3 0.037 12.8 2.3 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF4083 PF13314.6 ETS82438.1 - 9.4 6.3 7.3 1.5 8.8 1.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4083) Carboxyl_trans PF01039.22 ETS82440.1 - 0.076 11.6 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Carboxyl transferase domain SBP_bac_6 PF13343.6 ETS82441.1 - 6.7e-16 58.4 0.7 5.5e-15 55.5 0.7 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 ETS82441.1 - 6.1e-08 33.0 8.3 3.4e-07 30.5 8.3 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 ETS82441.1 - 1.7e-06 28.1 3.1 7.3e-05 22.7 3.1 2.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 ETS82441.1 - 0.00013 21.8 0.1 0.00021 21.1 0.1 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein FAD_binding_4 PF01565.23 ETS82442.1 - 6.6e-21 74.5 0.1 1.3e-20 73.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS82442.1 - 0.16 12.1 0.3 0.5 10.5 0.0 1.9 2 0 0 2 2 2 0 Berberine and berberine like Zn_clus PF00172.18 ETS82443.1 - 1.2e-07 31.8 9.3 1.7e-07 31.2 9.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS82443.1 - 0.0015 17.4 0.3 0.0024 16.8 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CorA PF01544.18 ETS82444.1 - 2.1e-05 24.0 7.3 0.00083 18.8 7.3 2.2 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Sigma70_ner PF04546.13 ETS82444.1 - 9.7 6.0 8.0 3.3 7.5 1.3 2.3 1 1 1 2 2 2 0 Sigma-70, non-essential region AA_permease_2 PF13520.6 ETS82445.1 - 4.7e-30 104.8 21.1 7.3e-30 104.1 21.1 1.3 1 1 0 1 1 1 1 Amino acid permease DUF751 PF05421.11 ETS82445.1 - 0.52 11.1 0.1 0.52 11.1 0.1 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF751) Pkinase PF00069.25 ETS82446.1 - 4.1e-13 49.3 0.0 1e-12 48.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain TPR_14 PF13428.6 ETS82446.1 - 0.12 13.3 0.1 0.5 11.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Kdo PF06293.14 ETS82446.1 - 0.15 11.4 0.1 0.31 10.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ADH_zinc_N PF00107.26 ETS82447.1 - 5.1e-28 97.7 1.1 9.5e-28 96.8 1.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS82447.1 - 5.7e-24 84.1 0.7 2e-23 82.4 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ETS82447.1 - 1.8e-07 32.3 0.0 2.6e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 ETS82447.1 - 0.011 15.2 0.1 0.015 14.7 0.1 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DFP PF04127.15 ETS82447.1 - 0.089 12.6 0.2 0.15 11.9 0.2 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Peptidase_S15 PF02129.18 ETS82448.1 - 1.5e-37 129.7 2.6 4.1e-36 125.0 0.8 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ETS82448.1 - 6.2e-23 81.9 0.0 1.4e-22 80.7 0.0 1.6 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Nodulin_late PF07127.11 ETS82450.1 - 0.39 11.1 2.5 0.78 10.1 0.9 2.3 2 0 0 2 2 2 0 Late nodulin protein DeoC PF01791.9 ETS82451.1 - 5e-10 39.4 0.5 6.3e-10 39.1 0.5 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DUF1805 PF08827.11 ETS82451.1 - 0.058 13.7 0.8 1.1 9.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1805) Abhydrolase_1 PF00561.20 ETS82452.1 - 4.3e-17 62.6 0.0 6.9e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS82452.1 - 4.5e-17 63.4 0.0 6.7e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS82452.1 - 7.1e-08 32.0 0.0 9.5e-08 31.6 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 ETS82452.1 - 0.00016 21.1 0.0 0.019 14.3 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.20 ETS82452.1 - 0.0002 21.6 0.0 0.00031 20.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 ETS82452.1 - 0.0023 17.7 0.3 0.069 12.9 0.2 2.1 1 1 0 2 2 2 1 PGAP1-like protein Esterase PF00756.20 ETS82452.1 - 0.0035 17.0 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF1057 PF06342.12 ETS82452.1 - 0.0035 16.4 0.0 0.0055 15.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Palm_thioest PF02089.15 ETS82452.1 - 0.006 16.5 0.0 0.008 16.0 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 ETS82452.1 - 0.017 14.6 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF900 PF05990.12 ETS82452.1 - 0.041 13.4 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) UPF0227 PF05728.12 ETS82452.1 - 0.052 13.5 0.2 0.11 12.4 0.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 ETS82452.1 - 0.054 13.3 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family Acyl_transf_1 PF00698.21 ETS82452.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase domain MBOAT_2 PF13813.6 ETS82453.1 - 5.6e-22 77.8 2.0 7.7e-22 77.4 0.6 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family NAD_binding_2 PF03446.15 ETS82457.1 - 1.2e-30 106.7 0.1 4.1e-30 105.0 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ETS82457.1 - 2.3e-10 40.7 0.9 3.7e-10 40.1 0.9 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 ETS82457.1 - 9e-10 38.8 0.1 2.5e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 ETS82457.1 - 5e-07 30.2 0.1 1.6e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 ETS82457.1 - 0.0026 18.0 0.1 0.0075 16.5 0.1 1.8 1 1 0 1 1 1 1 TrkA-N domain OCD_Mu_crystall PF02423.15 ETS82457.1 - 0.0075 15.2 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family PG_isomerase_N PF18353.1 ETS82457.1 - 0.21 12.0 3.1 0.67 10.4 0.1 2.7 2 1 0 2 2 2 0 Phosphoglucose isomerase N-terminal domain ADH_zinc_N PF00107.26 ETS82458.1 - 7.6e-13 48.6 0.1 2.8e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS82458.1 - 1.3e-07 31.5 0.1 1.1e-06 28.5 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ETS82458.1 - 0.00018 22.5 0.0 0.00038 21.5 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase HET PF06985.11 ETS82459.1 - 4.6e-10 40.0 2.9 4.6e-10 40.0 2.9 3.0 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) HET PF06985.11 ETS82460.1 - 7.4e-25 88.0 0.1 1.6e-24 86.9 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.23 ETS82461.1 - 5e-17 61.9 1.0 1.2e-16 60.8 0.7 1.8 2 0 0 2 2 2 1 FAD binding domain Ank_2 PF12796.7 ETS82462.1 - 6.7e-46 154.8 9.0 4.6e-17 62.4 0.4 3.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS82462.1 - 7.4e-23 80.6 0.1 1.6e-11 44.5 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ETS82462.1 - 6.2e-21 73.9 0.3 7e-06 26.3 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 ETS82462.1 - 3.2e-17 62.3 0.1 4.2e-08 33.3 0.0 4.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS82462.1 - 7.6e-14 50.5 7.0 0.00079 19.7 0.0 6.3 7 0 0 7 7 7 4 Ankyrin repeat AAA_16 PF13191.6 ETS82462.1 - 1.8e-08 34.9 0.8 6.1e-08 33.2 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 ETS82462.1 - 1.6e-06 28.1 0.2 4.2e-06 26.8 0.2 1.8 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ETS82462.1 - 8e-05 22.9 0.1 0.0011 19.3 0.0 2.8 2 1 1 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 ETS82462.1 - 0.033 13.9 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Ank_2 PF12796.7 ETS82463.1 - 2e-30 105.2 1.3 2.2e-08 34.6 0.0 4.7 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS82463.1 - 3e-24 85.1 1.2 2.8e-06 27.8 0.1 6.7 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS82463.1 - 1.9e-23 82.2 3.9 0.00028 21.1 0.1 6.5 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS82463.1 - 7.8e-20 68.9 5.6 0.093 13.3 0.0 8.7 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 ETS82463.1 - 2.6e-16 59.3 8.6 0.00048 20.5 0.1 7.5 7 0 0 7 7 7 4 Ankyrin repeat RelA_SpoT PF04607.17 ETS82463.1 - 7.6e-10 39.1 0.0 1.7e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins Helo_like_N PF17111.5 ETS82463.1 - 0.0037 16.7 0.5 0.0075 15.7 0.5 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins FA_hydroxylase PF04116.13 ETS82464.1 - 1.1e-22 80.8 17.7 1.4e-22 80.5 15.6 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Glycos_transf_2 PF00535.26 ETS82465.1 - 4.1e-25 88.5 0.0 1e-24 87.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ETS82465.1 - 1.1e-22 81.1 0.0 1.9e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Polysacc_deac_1 PF01522.21 ETS82465.1 - 2.9e-21 75.6 0.1 9e-21 74.0 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_trans_2_3 PF13632.6 ETS82465.1 - 9.7e-15 55.0 0.1 2.6e-14 53.6 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ETS82465.1 - 6.5e-09 35.5 0.0 2e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 ETS82465.1 - 3.6e-06 25.9 0.0 0.0027 16.4 0.0 2.4 2 1 1 3 3 3 2 Chitin synthase Glyco_tranf_2_2 PF10111.9 ETS82465.1 - 1.9e-05 24.3 0.1 2.9e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 ETS82465.1 - 0.0094 16.4 0.1 0.024 15.2 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 FixQ PF05545.11 ETS82465.1 - 0.027 14.4 0.1 0.095 12.7 0.1 1.9 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF2316 PF10078.9 ETS82465.1 - 0.076 13.3 0.0 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) MFS_1 PF07690.16 ETS82467.1 - 1e-21 77.3 54.7 2.2e-15 56.5 25.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3433 PF11915.8 ETS82468.1 - 1.7e-11 44.4 15.4 1.7e-08 34.8 0.9 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) HET PF06985.11 ETS82469.1 - 1.5e-12 48.1 3.2 8e-09 36.0 0.1 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Phage_holin_3_6 PF07332.11 ETS82470.1 - 1.4 9.0 14.3 0.35 10.9 1.9 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF5597 PF18120.1 ETS82472.1 - 1.7e-21 76.7 0.0 2.6e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 ETS82472.1 - 2.1e-08 33.9 0.0 5.5e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 ETS82472.1 - 1.6e-07 31.2 0.0 0.0012 18.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 NUC130_3NT PF08158.12 ETS82472.1 - 0.0099 16.2 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 1 NUC130/3NT domain TGF_beta_GS PF08515.12 ETS82473.1 - 0.3 10.6 2.7 13 5.4 0.1 2.4 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif BNR PF02012.20 ETS82473.1 - 3.3 8.1 10.0 7.6 7.0 1.3 4.0 3 0 0 3 3 3 0 BNR/Asp-box repeat Fungal_trans PF04082.18 ETS82474.1 - 1.5e-11 43.8 3.0 2.6e-11 43.0 3.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS82474.1 - 1.7e-05 24.8 7.0 3.7e-05 23.8 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 ETS82474.1 - 0.11 10.9 0.4 6.1 5.2 0.5 2.2 1 1 1 2 2 2 0 Centromere DNA-binding protein complex CBF3 subunit B Sugar_tr PF00083.24 ETS82475.1 - 2.4e-59 201.4 12.0 2.7e-59 201.2 12.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS82475.1 - 2.7e-08 33.1 16.0 2.7e-08 33.1 16.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 ETS82476.1 - 2.5e-24 85.7 0.1 4.1e-10 40.1 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS82476.1 - 2.1e-17 63.2 0.2 9.5e-10 38.8 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS82476.1 - 3.2e-17 62.1 0.3 2e-05 24.8 0.0 5.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 ETS82476.1 - 2.7e-13 49.9 0.1 3.2e-06 27.3 0.0 3.5 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS82476.1 - 7.2e-13 47.5 0.0 0.0028 18.0 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat CorA PF01544.18 ETS82476.1 - 1.8e-11 43.9 0.5 4.1e-11 42.7 0.5 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 ETS82476.1 - 0.021 13.6 0.2 0.045 12.5 0.2 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_holin_3_6 PF07332.11 ETS82476.1 - 0.053 13.6 1.3 0.1 12.6 1.3 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III HET PF06985.11 ETS82478.1 - 2.8e-33 115.3 0.8 4.6e-33 114.6 0.8 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cellulase PF00150.18 ETS82479.1 - 8.5e-34 117.3 2.3 1.5e-33 116.5 2.3 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 ETS82479.1 - 2.5e-23 82.0 7.8 9e-23 80.2 4.4 3.2 2 1 0 2 2 2 1 Carbohydrate binding domain X2 Glyco_hydro_43 PF04616.14 ETS82480.1 - 1.6e-29 103.1 0.3 5e-29 101.5 0.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Abhydrolase_6 PF12697.7 ETS82481.1 - 2e-19 71.1 0.1 2.4e-19 70.8 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS82481.1 - 0.00024 20.9 0.0 0.08 12.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS82481.1 - 0.00051 19.4 0.0 0.00091 18.6 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 ETS82481.1 - 0.0077 15.9 0.0 0.013 15.2 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PGAP1 PF07819.13 ETS82481.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.20 ETS82481.1 - 0.019 15.1 0.0 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain Peptidase_S9 PF00326.21 ETS82481.1 - 0.024 14.1 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 ETS82481.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 ETS82481.1 - 0.2 10.5 0.0 0.34 9.8 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme Lipase_2 PF01674.18 ETS82481.1 - 0.25 10.8 0.0 0.37 10.3 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) SnoaL_2 PF12680.7 ETS82483.1 - 1.7e-07 31.8 0.0 2.2e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain E1-E2_ATPase PF00122.20 ETS82483.1 - 0.15 11.5 0.1 0.83 9.2 0.0 1.9 1 1 1 2 2 2 0 E1-E2 ATPase AMP-binding PF00501.28 ETS82484.1 - 1.7e-90 303.7 0.0 2.4e-90 303.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 ETS82484.1 - 6.1e-74 248.8 0.0 1.4e-73 247.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ETS82484.1 - 1.2e-55 188.2 0.3 2.8e-55 187.0 0.3 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 ETS82484.1 - 4.9e-46 157.3 0.2 8.7e-46 156.5 0.2 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ETS82484.1 - 1.2e-41 143.3 1.0 1.8e-41 142.7 0.2 1.7 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ETS82484.1 - 6.2e-39 132.7 1.0 2.2e-38 130.9 1.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 ETS82484.1 - 1e-13 51.9 0.0 2.3e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain KAsynt_C_assoc PF16197.5 ETS82484.1 - 1.4e-13 51.3 0.0 3.9e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension AMP-binding_C PF13193.6 ETS82484.1 - 3e-13 50.5 0.0 1.1e-12 48.8 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 ETS82484.1 - 9.4e-13 48.3 0.1 9.6e-08 32.3 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site adh_short PF00106.25 ETS82484.1 - 2.8e-11 43.2 0.1 7.6e-11 41.8 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Abhydrolase_6 PF12697.7 ETS82484.1 - 2.9e-05 24.8 3.6 2.9e-05 24.8 3.6 4.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 ETS82484.1 - 0.00024 20.6 0.5 0.011 15.2 0.2 2.7 3 0 0 3 3 3 1 Thiolase, N-terminal domain Abhydrolase_3 PF07859.13 ETS82484.1 - 0.0011 18.8 0.1 0.0061 16.4 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Epimerase PF01370.21 ETS82484.1 - 0.0062 16.0 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS82484.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ETS82484.1 - 0.014 14.6 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ETS82484.1 - 0.042 12.8 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ETS82484.1 - 0.087 12.0 0.6 0.24 10.5 0.6 1.7 1 1 0 1 1 1 0 Male sterility protein DUF5597 PF18120.1 ETS82485.1 - 8.1e-24 84.2 0.1 1.3e-23 83.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 ETS82485.1 - 3.4e-11 43.1 0.0 4.8e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 ETS82485.1 - 2e-09 37.5 0.0 1.3e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.20 ETS82485.1 - 0.053 12.7 0.0 0.095 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Chitin_synth_2 PF03142.15 ETS82486.1 - 2.6e-248 824.9 1.7 3.6e-248 824.5 1.7 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ETS82486.1 - 1.5e-75 254.8 0.0 7.5e-75 252.5 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 ETS82486.1 - 4.1e-17 61.8 0.0 2e-16 59.6 0.1 2.1 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 ETS82486.1 - 9.3e-17 60.9 1.5 3.9e-13 49.3 0.1 3.1 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 ETS82486.1 - 1.4e-12 48.0 5.5 1.4e-12 48.0 5.5 2.0 2 0 0 2 2 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ETS82486.1 - 1.6e-10 41.2 0.0 5.3e-09 36.3 0.1 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ETS82486.1 - 0.00018 21.4 0.0 0.17 11.7 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 AAA_22 PF13401.6 ETS82486.1 - 0.032 14.5 0.2 0.18 12.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ETS82486.1 - 0.048 14.0 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 ETS82486.1 - 0.059 12.9 0.0 1.9 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ETS82486.1 - 0.08 13.5 0.0 0.27 11.7 0.0 1.8 2 0 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 ETS82486.1 - 0.1 12.5 0.0 0.4 10.6 0.1 1.9 2 0 0 2 2 2 0 RsgA GTPase TrwB_AAD_bind PF10412.9 ETS82486.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 ETS82486.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 ETS82486.1 - 0.17 11.3 0.6 0.71 9.3 0.6 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Chitin_synth_2 PF03142.15 ETS82487.1 - 6.2e-231 767.6 0.2 9e-231 767.1 0.2 1.1 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 ETS82487.1 - 3.2e-16 59.0 0.9 3.4e-15 55.7 1.9 2.1 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 ETS82487.1 - 1.6e-15 57.0 1.6 2.2e-11 43.7 0.1 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 ETS82487.1 - 2.2e-12 47.3 2.8 2.2e-12 47.3 2.8 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ETS82487.1 - 5.5e-10 39.5 0.0 3.3e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 ETS82487.1 - 2.8e-07 29.2 0.0 2.3e-06 26.1 0.0 1.9 1 1 1 2 2 2 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 ETS82487.1 - 0.0011 18.4 0.0 0.003 17.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ETS82487.1 - 0.0012 18.7 0.0 0.19 11.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 BCDHK_Adom3 PF10436.9 ETS82488.1 - 2.6e-47 160.6 0.0 3.5e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ETS82488.1 - 2.5e-11 44.1 0.0 5.1e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.16 ETS82489.1 - 5.8e-13 49.3 0.3 9.7e-13 48.6 0.3 1.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 RIBIOP_C PF04950.12 ETS82490.1 - 7.4e-95 317.7 0.0 7.4e-95 317.7 0.0 2.0 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 ETS82490.1 - 6.8e-29 99.8 0.2 2.3e-28 98.1 0.0 2.1 2 0 0 2 2 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 ETS82490.1 - 1.7e-05 25.1 0.0 4.3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ETS82490.1 - 4.2e-05 23.7 0.3 0.00026 21.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS82490.1 - 4.6e-05 23.9 0.0 0.00015 22.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ETS82490.1 - 0.00012 22.6 2.6 0.035 14.7 0.0 3.7 3 0 0 3 3 3 1 AAA domain GTP_EFTU PF00009.27 ETS82490.1 - 0.00023 20.8 0.0 0.056 13.0 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 ETS82490.1 - 0.00034 21.2 0.3 0.0036 17.8 0.0 2.6 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.12 ETS82490.1 - 0.00035 20.5 0.0 0.00095 19.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 ETS82490.1 - 0.00038 20.9 0.0 0.00092 19.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 ETS82490.1 - 0.0014 18.7 0.0 0.0038 17.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.6 ETS82490.1 - 0.0026 18.1 0.0 0.008 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ETS82490.1 - 0.0049 16.8 0.0 0.091 12.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase RNA_helicase PF00910.22 ETS82490.1 - 0.0055 17.1 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 ETS82490.1 - 0.0072 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 ETS82490.1 - 0.0073 16.0 0.0 0.027 14.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ETS82490.1 - 0.014 15.4 0.0 0.052 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 ETS82490.1 - 0.015 15.5 0.1 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 ETS82490.1 - 0.017 14.8 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 ETS82490.1 - 0.018 14.8 0.0 0.062 13.0 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 ETS82490.1 - 0.023 14.6 0.5 0.43 10.5 0.1 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 ETS82490.1 - 0.03 14.6 1.3 0.068 13.4 0.0 2.3 2 0 0 2 2 1 0 AAA domain Ploopntkinase3 PF18751.1 ETS82490.1 - 0.031 14.2 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 NTPase_1 PF03266.15 ETS82490.1 - 0.042 13.8 0.2 0.083 12.8 0.2 1.5 1 0 0 1 1 1 0 NTPase Rad17 PF03215.15 ETS82490.1 - 0.049 13.6 0.1 0.14 12.0 0.0 1.8 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_5 PF07728.14 ETS82490.1 - 0.052 13.5 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ETS82490.1 - 0.077 12.6 0.0 0.23 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ETS82490.1 - 0.085 12.4 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 ETS82490.1 - 0.096 12.6 1.5 0.15 11.9 0.0 2.0 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea DUF2207 PF09972.9 ETS82490.1 - 1.5 7.5 6.0 2.7 6.6 6.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Na_Ca_ex PF01699.24 ETS82492.1 - 4.5e-24 85.1 28.2 7.8e-13 48.6 7.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Mac PF12464.8 ETS82493.1 - 1.2e-13 51.1 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 ETS82493.1 - 1.2e-13 50.1 11.4 2.4e-12 46.0 4.4 3.2 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ETS82493.1 - 1.6e-13 50.2 11.9 1.4e-12 47.1 3.8 3.3 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Subtilosin_A PF11420.8 ETS82493.1 - 0.27 11.2 0.1 0.27 11.2 0.1 2.3 3 0 0 3 3 3 0 Bacteriocin subtilosin A Polysacc_deac_1 PF01522.21 ETS82494.1 - 2.8e-26 91.9 0.0 4.4e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2194 PF09960.9 ETS82494.1 - 0.03 12.7 0.0 0.038 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) zf-RING_2 PF13639.6 ETS82495.1 - 6.2e-09 36.0 8.3 1.3e-08 35.0 8.3 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 ETS82495.1 - 6.3e-06 26.3 7.8 1.9e-05 24.7 7.8 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 ETS82495.1 - 2.5e-05 24.5 6.7 7.2e-05 23.0 6.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ETS82495.1 - 7.7e-05 22.7 2.2 0.00023 21.1 2.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 ETS82495.1 - 0.001 19.1 7.2 0.0027 17.8 7.2 1.8 1 0 0 1 1 1 1 RING-variant domain Zn_ribbon_17 PF17120.5 ETS82495.1 - 0.0022 17.6 4.9 0.0044 16.6 4.9 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 ETS82495.1 - 0.0033 17.3 9.0 0.0076 16.1 9.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 ETS82495.1 - 0.006 16.4 2.5 0.006 16.4 2.5 1.8 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.6 ETS82495.1 - 0.012 15.5 7.7 0.026 14.4 7.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PWI PF01480.17 ETS82495.1 - 0.056 13.8 0.8 2.2 8.7 0.1 3.5 2 0 0 2 2 2 0 PWI domain zf-RING-like PF08746.11 ETS82495.1 - 0.14 12.5 10.7 0.15 12.4 7.4 2.3 2 0 0 2 2 2 0 RING-like domain zf-C3HC4_3 PF13920.6 ETS82495.1 - 0.29 11.0 9.7 0.027 14.3 5.0 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_9 PF13901.6 ETS82495.1 - 0.49 10.3 5.7 1.2 9.1 5.7 1.6 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PHD PF00628.29 ETS82495.1 - 1.3 9.0 6.7 3.1 7.7 6.7 1.7 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 ETS82495.1 - 2 8.4 8.5 0.77 9.7 5.2 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ETS82495.1 - 3 7.9 8.2 7.2 6.7 8.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Zf_RING PF16744.5 ETS82495.1 - 3.3 7.9 4.6 4.4 7.5 2.8 2.1 2 0 0 2 2 2 0 KIAA1045 RING finger zf-RING_4 PF14570.6 ETS82495.1 - 4.5 7.1 6.7 1.4e+02 2.4 6.7 2.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain MgtE_N PF03448.17 ETS82496.1 - 0.24 12.0 8.3 7.2 7.3 0.4 3.0 2 0 0 2 2 2 0 MgtE intracellular N domain HET PF06985.11 ETS82497.1 - 2.7e-27 95.9 0.6 5.5e-27 94.9 0.6 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RhoGAP PF00620.27 ETS82500.1 - 4.1e-20 72.2 0.0 8.4e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Helo_like_N PF17111.5 ETS82500.1 - 0.00098 18.5 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF1213 PF06740.12 ETS82500.1 - 0.88 10.2 3.3 10 6.8 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1213) HeLo PF14479.6 ETS82501.1 - 6e-10 39.3 2.8 6e-10 39.3 2.8 1.8 2 0 0 2 2 2 1 Prion-inhibition and propagation Pkinase PF00069.25 ETS82501.1 - 0.0097 15.3 0.0 0.026 13.9 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 ETS82502.1 - 4.1e-36 124.7 0.0 5.8e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS82502.1 - 1.2e-24 87.0 0.0 1.8e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ETS82502.1 - 0.0016 18.4 2.7 0.0037 17.2 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 ETS82502.1 - 0.002 17.5 0.5 0.0047 16.3 0.5 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ETS82502.1 - 0.017 14.0 0.0 0.049 12.4 0.0 1.7 1 1 1 2 2 2 0 Fungal protein kinase Glyco_hydro_1 PF00232.18 ETS82503.1 - 1.2e-68 231.6 0.6 5.7e-68 229.4 0.6 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Palm_thioest PF02089.15 ETS82504.1 - 1.2e-81 274.1 0.0 1.4e-81 273.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 ETS82504.1 - 0.00014 21.5 0.0 0.0018 17.9 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 2) DUF915 PF06028.11 ETS82504.1 - 0.00018 20.9 0.1 0.0004 19.8 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 ETS82504.1 - 0.045 13.4 0.1 0.099 12.3 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Prosystemin PF07376.11 ETS82504.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Prosystemin Ribosomal_L1 PF00687.21 ETS82505.1 - 3.9e-62 209.6 2.4 3.9e-62 209.6 2.4 1.5 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Cyclin_N PF00134.23 ETS82506.1 - 8.3e-06 25.6 0.1 1.4e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Glyco_hydr_30_2 PF14587.6 ETS82507.1 - 1.3e-12 48.1 0.0 2.7e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 ETS82507.1 - 2.2e-10 40.3 0.2 3.5e-10 39.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 ETS82507.1 - 5.1e-10 39.4 5.6 1.5e-09 37.9 5.6 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 ETS82507.1 - 1e-09 37.8 0.3 1.6e-09 37.2 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Abhydrolase_3 PF07859.13 ETS82508.1 - 4.1e-07 30.1 0.1 0.0031 17.4 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 ETS82508.1 - 3.2e-05 23.6 0.0 0.0014 18.2 0.0 2.7 3 0 0 3 3 3 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 ETS82508.1 - 5.6e-05 22.7 0.0 0.00052 19.5 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ETS82508.1 - 0.0025 17.5 0.0 0.2 11.3 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS82508.1 - 0.01 15.1 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 YjeF_N PF03853.15 ETS82508.1 - 0.039 13.8 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus FSH1 PF03959.13 ETS82508.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) GST_N_2 PF13409.6 ETS82510.1 - 1.1e-20 73.7 0.1 3e-20 72.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS82510.1 - 3.9e-14 52.4 0.0 7.2e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ETS82510.1 - 5.7e-08 32.9 0.0 1.1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ETS82510.1 - 5.8e-06 26.6 0.0 0.025 15.0 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ETS82510.1 - 0.0011 19.1 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ETS82510.1 - 0.025 15.1 0.0 0.043 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ThiF PF00899.21 ETS82511.1 - 2.4e-109 364.4 0.0 3e-74 249.5 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 ETS82511.1 - 1.5e-95 319.9 1.6 2.2e-95 319.4 1.6 1.2 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 ETS82511.1 - 6.2e-32 110.2 0.1 1.5e-31 109.0 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 ETS82511.1 - 1.6e-31 108.3 0.2 4e-31 107.0 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 ETS82511.1 - 6e-25 87.2 0.6 2e-24 85.6 0.6 2.0 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 ETS82511.1 - 0.09 13.2 0.0 3.1 8.3 0.0 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding CBM_14 PF01607.24 ETS82512.1 - 0.12 12.6 1.4 0.77 10.0 0.7 2.6 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain Kelch_5 PF13854.6 ETS82513.1 - 3.2e-10 39.8 6.6 2.5e-09 36.9 0.4 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.25 ETS82513.1 - 8.2e-05 22.1 1.2 4 7.1 0.0 4.2 4 0 0 4 4 4 3 Kelch motif GlutR_N PF05201.15 ETS82514.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain His_Phos_1 PF00300.22 ETS82515.1 - 2.8e-35 121.8 0.0 3.9e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF5534 PF17686.1 ETS82516.1 - 0.062 13.6 0.1 0.088 13.1 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5534) Helo_like_N PF17111.5 ETS82517.1 - 1.1e-06 28.2 0.6 2.2e-06 27.2 0.6 1.6 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF963 PF06131.11 ETS82517.1 - 0.0043 16.4 8.0 0.014 14.8 8.0 1.9 1 0 0 1 1 1 1 Schizosaccharomyces pombe repeat of unknown function (DUF963) p450 PF00067.22 ETS82518.1 - 3.9e-19 68.7 0.0 4e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LysM PF01476.20 ETS82519.1 - 3.7e-21 74.9 3.5 7.1e-07 29.2 0.0 5.3 6 0 0 6 6 6 4 LysM domain Chitin_bind_1 PF00187.19 ETS82519.1 - 6.4e-10 39.3 53.5 9.3e-06 26.0 18.4 4.1 3 0 0 3 3 3 2 Chitin recognition protein Glyco_hydro_18 PF00704.28 ETS82520.1 - 5.7e-73 246.4 2.8 1.4e-72 245.1 2.8 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ETS82520.1 - 8.1e-17 61.4 45.8 6.1e-14 52.2 16.4 4.6 5 0 0 5 5 5 2 Chitin recognition protein HET PF06985.11 ETS82522.1 - 1.9e-27 96.4 0.0 4.8e-27 95.1 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Eaf7 PF07904.13 ETS82523.1 - 4.1e-27 94.6 0.1 4.1e-27 94.6 0.1 2.6 2 1 0 2 2 1 1 Chromatin modification-related protein EAF7 PPP4R2 PF09184.11 ETS82523.1 - 0.054 13.1 18.7 0.08 12.5 18.7 1.3 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 ETS82523.1 - 0.055 12.8 14.8 0.099 12.0 14.8 1.5 1 0 0 1 1 1 0 NOA36 protein CDC27 PF09507.10 ETS82523.1 - 0.22 10.9 27.5 0.4 10.0 27.5 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CNDH2_C PF16858.5 ETS82523.1 - 0.39 10.5 12.4 0.61 9.9 12.4 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF2486 PF10667.9 ETS82523.1 - 0.57 10.4 30.0 0.16 12.2 22.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) Astro_capsid_p PF12226.8 ETS82523.1 - 2.5 7.2 23.3 4.5 6.3 23.3 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 ETS82523.1 - 3.5 5.7 29.1 4.6 5.3 29.1 1.1 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 ETS82523.1 - 5.2 6.8 19.4 8.8 6.1 19.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop53 PF07767.11 ETS82523.1 - 6 6.1 27.2 14 4.9 27.2 1.6 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SAPS PF04499.15 ETS82523.1 - 7.9 5.1 12.2 9.5 4.9 12.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Paf1 PF03985.13 ETS82523.1 - 9.8 5.0 21.8 14 4.6 21.8 1.2 1 0 0 1 1 1 0 Paf1 GCP_C_terminal PF04130.13 ETS82524.1 - 5e-78 262.7 0.0 8.7e-78 261.9 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 ETS82524.1 - 1.7e-31 110.0 0.0 3.7e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DASH_Ask1 PF08655.10 ETS82525.1 - 7.6e-31 105.8 0.3 1.3e-30 105.1 0.3 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 SBF2 PF12335.8 ETS82525.1 - 0.18 11.4 0.6 0.3 10.7 0.6 1.4 1 0 0 1 1 1 0 Myotubularin protein p450 PF00067.22 ETS82527.1 - 1.1e-51 176.1 0.0 1.5e-51 175.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S10 PF00450.22 ETS82528.1 - 1.6e-82 278.2 0.3 2.4e-82 277.6 0.3 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Acetyltransf_10 PF13673.7 ETS82529.1 - 0.0036 17.2 0.0 0.0062 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS82529.1 - 0.0055 17.1 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Destabilase PF05497.12 ETS82529.1 - 0.035 14.5 0.0 0.079 13.3 0.0 1.6 1 0 0 1 1 1 0 Destabilase Acetyltransf_9 PF13527.7 ETS82529.1 - 0.04 14.0 0.0 3.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ufm1 PF03671.14 ETS82529.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fold modifier 1 protein Rhodanese PF00581.20 ETS82530.1 - 6.1e-14 52.4 0.0 8.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Yip1 PF04893.17 ETS82531.1 - 9.3e-12 45.0 16.5 1.9e-11 44.0 16.5 1.5 1 1 0 1 1 1 1 Yip1 domain ubiquitin PF00240.23 ETS82532.1 - 3.9e-34 116.2 0.6 5.1e-34 115.8 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 ETS82532.1 - 2.6e-31 107.2 11.1 4e-31 106.7 11.1 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 ETS82532.1 - 4.3e-16 58.5 0.6 6.2e-16 58.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ETS82532.1 - 1.4e-05 25.5 0.2 4.9e-05 23.7 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 ETS82532.1 - 0.0034 17.7 0.1 0.0053 17.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 ETS82532.1 - 0.0036 17.2 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 ETS82532.1 - 0.0064 16.6 0.1 0.013 15.6 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 ETS82532.1 - 0.026 14.6 0.9 6.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 ETS82532.1 - 0.027 15.0 0.1 0.031 14.8 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 ETS82532.1 - 0.099 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain zf-RRN7 PF11781.8 ETS82534.1 - 3.5e-06 26.6 3.3 5.5e-06 26.0 3.3 1.3 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 eIF-5a PF01287.20 ETS82535.1 - 3.7e-24 84.6 2.5 2.4e-22 78.8 0.8 2.2 2 0 0 2 2 2 2 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 ETS82535.1 - 0.001 19.0 0.1 0.002 18.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.12 ETS82536.1 - 1.4e-119 400.2 0.0 1.8e-119 399.8 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 ETS82536.1 - 1.1e-07 30.7 0.2 1.2e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 Exocyst complex component Sec3 DUF812 PF05667.11 ETS82536.1 - 0.037 12.9 0.4 0.061 12.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4795 PF16043.5 ETS82536.1 - 0.068 12.8 0.4 0.12 11.9 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF1664 PF07889.12 ETS82536.1 - 0.074 13.1 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) GAS PF13851.6 ETS82536.1 - 0.11 11.9 0.2 0.23 10.8 0.2 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mer2 PF09074.10 ETS82536.1 - 0.15 11.9 0.2 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 Mer2 DUF5304 PF17230.2 ETS82536.1 - 2 8.7 4.5 0.89 9.8 0.2 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5304) RabGAP-TBC PF00566.18 ETS82537.1 - 4.5e-20 72.2 0.0 8e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MMS1_N PF10433.9 ETS82538.1 - 1e-57 195.9 0.0 3.8e-57 194.0 0.0 1.9 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term IKI3 PF04762.12 ETS82538.1 - 0.00035 18.7 0.0 0.03 12.3 0.0 2.2 2 0 0 2 2 2 2 IKI3 family CPSF_A PF03178.15 ETS82538.1 - 0.035 13.4 0.0 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 CPSF A subunit region GTP_EFTU PF00009.27 ETS82539.1 - 2.3e-34 118.6 0.0 2.3e-34 118.6 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 ETS82539.1 - 6.7e-20 71.2 0.0 1.8e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 ETS82539.1 - 1.5e-08 34.4 2.0 2e-08 34.0 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 ETS82539.1 - 7.8e-08 32.6 8.4 1.1e-07 32.2 0.3 3.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ETS82539.1 - 2.2e-07 31.0 0.2 6.6e-06 26.2 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 ETS82539.1 - 0.00023 21.4 0.0 0.00073 19.8 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 ETS82539.1 - 0.0015 18.4 0.0 0.0015 18.4 0.0 2.4 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein Ras PF00071.22 ETS82539.1 - 0.037 13.6 0.0 0.21 11.2 0.0 2.5 1 1 0 1 1 1 0 Ras family RsgA_GTPase PF03193.16 ETS82539.1 - 0.064 13.2 0.3 0.82 9.6 0.1 2.8 2 1 0 2 2 2 0 RsgA GTPase TrkA_C PF02080.21 ETS82539.1 - 0.11 12.4 1.0 4 7.4 0.1 2.7 2 0 0 2 2 2 0 TrkA-C domain Ank_2 PF12796.7 ETS82540.1 - 1.1e-205 666.8 62.9 5.8e-15 55.7 0.1 16.5 2 2 15 19 19 19 19 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS82540.1 - 3.3e-131 426.1 28.3 1.1e-09 38.6 0.2 22.7 6 5 15 24 24 24 24 Ankyrin repeats (many copies) Ank PF00023.30 ETS82540.1 - 4.8e-117 377.8 56.9 1.4e-05 25.3 0.0 32.8 32 1 1 33 33 33 28 Ankyrin repeat Ank_3 PF13606.6 ETS82540.1 - 6e-112 351.9 22.4 0.00019 21.6 0.0 32.6 33 0 0 33 33 33 28 Ankyrin repeat Ank_5 PF13857.6 ETS82540.1 - 1.2e-107 350.5 42.8 3.4e-07 30.4 0.0 24.2 8 5 18 26 26 26 23 Ankyrin repeats (many copies) WD40 PF00400.32 ETS82541.1 - 1.6e-67 221.7 65.1 5.3e-10 39.7 0.6 13.1 13 0 0 13 13 13 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS82541.1 - 3.5e-33 113.7 22.6 5.8e-05 23.3 0.2 10.4 1 1 11 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ETS82541.1 - 2.7e-14 52.7 36.7 0.019 13.6 0.6 9.7 2 1 7 10 10 10 6 Nucleoporin Nup120/160 AAA_16 PF13191.6 ETS82541.1 - 5.6e-09 36.6 0.1 1.5e-08 35.2 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain eIF2A PF08662.11 ETS82541.1 - 4.3e-08 33.3 12.2 0.0089 15.9 0.1 4.5 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A NACHT PF05729.12 ETS82541.1 - 1.6e-07 31.4 0.1 3.1e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 ETS82541.1 - 0.00034 20.0 2.1 0.0009 18.6 0.7 1.9 1 1 1 2 2 2 1 KAP family P-loop domain AAA PF00004.29 ETS82541.1 - 0.00038 20.9 0.0 0.00078 19.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ge1_WD40 PF16529.5 ETS82541.1 - 0.0005 19.1 19.7 4.6 6.1 0.8 7.1 3 3 4 8 8 8 4 WD40 region of Ge1, enhancer of mRNA-decapping protein APS_kinase PF01583.20 ETS82541.1 - 0.0045 16.9 0.1 0.0076 16.1 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 ETS82541.1 - 0.018 15.6 0.0 0.041 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Nuc_deoxyri_tr2 PF15891.5 ETS82541.1 - 0.026 14.8 0.5 12 6.3 0.2 3.9 4 0 0 4 4 4 0 Nucleoside 2-deoxyribosyltransferase like Nbas_N PF15492.6 ETS82541.1 - 0.037 13.4 23.6 5.4 6.3 0.3 8.4 4 3 7 11 11 11 0 Neuroblastoma-amplified sequence, N terminal NB-ARC PF00931.22 ETS82541.1 - 0.037 13.2 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 ETS82541.1 - 0.094 13.0 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ETS82541.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1513 PF07433.11 ETS82541.1 - 3.8 6.5 10.6 19 4.2 0.0 5.0 3 2 1 6 6 6 0 Protein of unknown function (DUF1513) PNP_UDP_1 PF01048.20 ETS82542.1 - 5e-13 48.8 1.4 5.1e-12 45.5 1.4 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily CoA_binding_2 PF13380.6 ETS82543.1 - 3e-27 95.4 0.0 3.7e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Methyltransf_11 PF08241.12 ETS82544.1 - 4.9e-17 62.4 0.0 7.6e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS82544.1 - 2.3e-16 60.2 0.0 4e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS82544.1 - 1.4e-08 35.4 0.0 2.1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS82544.1 - 4.2e-07 29.9 0.0 5.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS82544.1 - 1e-06 28.7 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS82544.1 - 3.2e-06 26.6 0.0 4.6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ETS82544.1 - 0.00045 19.8 0.0 0.00071 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 ETS82544.1 - 0.0017 17.5 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.12 ETS82544.1 - 0.035 13.7 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 ETS82544.1 - 0.049 13.6 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 ETS82544.1 - 0.23 10.5 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase EF-hand_7 PF13499.6 ETS82545.1 - 6.7e-14 52.1 0.3 2.7e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 ETS82545.1 - 1.7e-12 47.4 0.0 4.6e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 ETS82545.1 - 7.7e-12 44.1 0.6 0.00014 21.5 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 ETS82545.1 - 1.4e-11 43.1 0.4 0.00053 19.4 0.0 4.0 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 ETS82545.1 - 2.7e-09 36.7 0.2 3.6e-05 23.5 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 ETS82545.1 - 0.33 10.5 1.9 37 4.0 0.3 3.3 3 1 0 3 3 3 0 EF hand Peptidase_M3 PF01432.20 ETS82546.1 - 4.7e-154 514.0 0.0 6.1e-154 513.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 ETS82546.1 - 0.057 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Effector protein p450 PF00067.22 ETS82547.1 - 5.5e-35 121.0 0.0 6.7e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 ETS82548.1 - 7.3e-39 133.8 54.0 9.1e-39 133.5 54.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS82548.1 - 6.3e-12 44.8 53.0 3.7e-11 42.3 53.0 1.8 1 1 0 1 1 1 1 Amino acid permease Abhydrolase_1 PF00561.20 ETS82549.1 - 5.2e-16 59.1 0.7 1.1e-15 58.1 0.7 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS82549.1 - 1.9e-15 58.1 0.4 1.9e-14 54.8 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS82549.1 - 1.4e-08 34.4 0.0 5e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 ETS82549.1 - 0.027 14.1 0.0 0.038 13.6 0.0 1.3 1 1 0 1 1 1 0 Putative esterase AXE1 PF05448.12 ETS82549.1 - 0.049 12.3 0.0 0.077 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 ETS82549.1 - 0.067 12.1 0.0 0.097 11.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Glyco_hydro_cc PF11790.8 ETS82550.1 - 1e-62 211.9 1.0 1.5e-62 211.3 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Zn_clus PF00172.18 ETS82551.1 - 2e-07 31.0 15.8 4.4e-07 29.9 15.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS82551.1 - 9.5e-05 21.4 2.5 0.00023 20.1 2.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain AIB PF15334.6 ETS82551.1 - 0.0061 15.9 0.4 0.011 15.1 0.4 1.5 1 0 0 1 1 1 1 Aurora kinase A and ninein interacting protein DUF3433 PF11915.8 ETS82552.1 - 1.1e-33 115.6 16.3 1.4e-21 76.7 2.6 4.0 3 0 0 3 3 3 3 Protein of unknown function (DUF3433) Peroxidase_2 PF01328.17 ETS82553.1 - 1e-49 169.7 0.0 1.2e-49 169.4 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 MFS_1 PF07690.16 ETS82554.1 - 3.6e-30 105.1 21.9 5e-30 104.6 21.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SdpI PF13630.6 ETS82554.1 - 5 7.3 0.0 5 7.3 0.0 4.2 4 2 0 4 4 4 0 SdpI/YhfL protein family GST_N_4 PF17172.4 ETS82555.1 - 1.8 9.4 4.1 26 5.6 0.3 3.1 2 1 0 2 2 2 0 Glutathione S-transferase N-terminal domain Spherulin4 PF12138.8 ETS82556.1 - 4.5e-84 281.9 5.8 1.4e-63 214.7 3.6 2.0 2 0 0 2 2 2 2 Spherulation-specific family 4 SRI PF08236.11 ETS82557.1 - 0.069 13.3 0.2 0.14 12.4 0.2 1.4 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain IER PF05760.12 ETS82557.1 - 0.16 12.2 6.1 0.054 13.8 2.7 1.8 1 1 1 2 2 2 0 Immediate early response protein (IER) Bul1_C PF04426.12 ETS82558.1 - 1.5e-05 24.6 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus Bul1_N PF04425.12 ETS82558.1 - 0.00083 18.2 0.0 0.0085 14.9 0.0 2.0 1 1 1 2 2 2 1 Bul1 N terminus Zip PF02535.22 ETS82559.1 - 1.6e-55 188.7 9.5 4.4e-55 187.2 9.5 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter OPT PF03169.15 ETS82560.1 - 2e-205 684.1 31.8 2.3e-205 683.9 31.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein 5-FTHF_cyc-lig PF01812.20 ETS82561.1 - 2e-27 96.3 0.0 3.7e-27 95.4 0.0 1.4 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.22 ETS82562.1 - 1.7e-15 56.4 0.1 2.1e-15 56.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 ETS82562.1 - 0.0039 16.8 0.1 0.0056 16.3 0.1 1.3 1 0 0 1 1 1 1 Hfq protein Xpo1 PF08389.12 ETS82563.1 - 2.9e-27 95.5 4.8 4.9e-27 94.8 0.2 3.7 4 1 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 ETS82563.1 - 1.3e-08 34.6 0.2 5.2e-08 32.7 0.2 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain UME PF08064.13 ETS82563.1 - 0.0064 16.4 2.3 1.3 9.0 0.0 4.8 4 1 1 5 5 5 1 UME (NUC010) domain GAT PF03127.14 ETS82563.1 - 0.0073 16.6 0.3 0.0073 16.6 0.3 3.1 3 0 0 3 3 3 1 GAT domain Importin_rep_3 PF18806.1 ETS82563.1 - 0.012 15.7 0.8 1.4 9.0 0.0 3.8 4 0 0 4 4 4 0 Importin 13 repeat Adaptin_N PF01602.20 ETS82563.1 - 0.012 14.2 1.6 0.46 9.0 0.3 2.6 2 1 0 2 2 2 0 Adaptin N terminal region SYCP2_ARLD PF18581.1 ETS82563.1 - 0.11 12.4 0.4 2.3 8.2 0.1 2.7 2 1 0 2 2 2 0 Synaptonemal complex 2 armadillo-repeat-like domain RVT_N PF13655.6 ETS82563.1 - 0.14 12.5 0.2 1.7 9.0 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase GTP_EFTU PF00009.27 ETS82564.1 - 2.7e-67 226.1 0.1 4e-67 225.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ETS82564.1 - 3.9e-32 110.6 0.0 1e-31 109.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 ETS82564.1 - 2e-21 75.8 0.0 4.9e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ETS82564.1 - 8.7e-13 48.5 0.1 2.7e-12 46.9 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 ETS82564.1 - 6e-11 42.3 0.0 2e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 ETS82564.1 - 0.00026 21.0 0.2 0.00059 19.9 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase NUDIX PF00293.28 ETS82565.1 - 7.9e-09 35.6 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 ETS82565.1 - 0.014 15.4 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) Acetyltransf_10 PF13673.7 ETS82566.1 - 2.5e-07 30.7 0.0 3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS82566.1 - 3.5e-06 27.4 0.0 5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS82566.1 - 3.7e-06 27.2 0.0 4.1e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ETS82566.1 - 3.8e-05 23.6 0.0 5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ETS82566.1 - 0.02 15.0 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Solute_trans_a PF03619.16 ETS82568.1 - 4.6e-101 337.8 11.2 5.5e-101 337.6 11.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha MFS_1 PF07690.16 ETS82569.1 - 1.9e-24 86.3 28.0 1.9e-24 86.3 28.0 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS82569.1 - 2.7e-08 33.1 32.2 1.5e-06 27.3 32.2 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.25 ETS82570.1 - 1.5e-68 231.0 0.0 1.9e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS82570.1 - 5.6e-32 111.0 0.0 7.4e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ETS82570.1 - 6.9e-06 25.2 0.1 9.6e-06 24.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ETS82570.1 - 2.8e-05 23.6 0.1 8.7e-05 22.0 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ETS82570.1 - 0.00042 20.3 0.1 0.0014 18.6 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ETS82570.1 - 0.002 17.5 0.0 0.074 12.4 0.0 2.1 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 ETS82570.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 ETS82570.1 - 0.022 14.4 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 AA_permease PF00324.21 ETS82571.1 - 1.8e-107 359.9 33.9 2.3e-107 359.6 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS82571.1 - 4.2e-26 91.8 35.1 1.7e-25 89.7 34.3 2.1 1 1 0 1 1 1 1 Amino acid permease Usher PF00577.20 ETS82571.1 - 0.25 10.1 0.1 0.36 9.6 0.1 1.1 1 0 0 1 1 1 0 Outer membrane usher protein Avl9 PF09794.9 ETS82572.1 - 4.1e-143 476.7 0.0 5.2e-143 476.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 ETS82572.1 - 4.8e-07 29.6 2.8 3.7e-05 23.5 0.1 3.6 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 ETS82572.1 - 1.1e-05 25.3 0.1 0.00046 20.1 0.0 2.5 2 0 0 2 2 2 1 Stabilization of polarity axis F-box-like PF12937.7 ETS82573.1 - 1.1e-07 31.6 0.5 1.1e-07 31.6 0.5 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ETS82573.1 - 1e-05 25.2 0.2 1e-05 25.2 0.2 2.0 2 0 0 2 2 2 1 F-box domain DUF585 PF04522.12 ETS82573.1 - 0.64 9.6 3.7 1.3 8.6 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF585) Fungal_trans PF04082.18 ETS82574.1 - 7.8e-65 218.5 0.0 1.3e-64 217.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 ETS82574.1 - 2.2e-07 31.0 10.5 0.00055 20.2 1.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS82574.1 - 0.41 11.6 15.5 0.41 11.6 0.7 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger FAD_binding_3 PF01494.19 ETS82575.1 - 3.8e-22 79.0 0.1 1e-21 77.6 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 ETS82575.1 - 0.00021 20.5 3.5 0.07 12.2 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ETS82575.1 - 0.0087 15.4 0.4 0.6 9.3 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ETS82575.1 - 0.021 14.2 0.1 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase SE PF08491.10 ETS82575.1 - 0.13 11.3 0.0 6.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase Fungal_trans PF04082.18 ETS82576.1 - 1.7e-12 46.9 0.3 4e-12 45.7 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS82576.1 - 1.5e-08 34.6 12.8 2.9e-08 33.7 12.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAP30_Sin3_bdg PF13867.6 ETS82577.1 - 3.5e-07 30.5 1.9 5.2e-07 29.9 0.4 2.0 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DnaJ_C PF01556.18 ETS82578.1 - 3.1e-37 127.9 0.0 4.3e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ETS82578.1 - 2.8e-23 81.8 0.5 2.8e-23 81.8 0.5 2.0 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ETS82578.1 - 4.3e-09 36.6 22.5 8.7e-09 35.6 22.5 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ETS82578.1 - 0.0076 16.2 2.0 0.0076 16.2 2.0 2.9 3 0 0 3 3 3 1 Tryptophan RNA-binding attenuator protein inhibitory protein BRO1 PF03097.18 ETS82579.1 - 1.9e-129 431.9 4.1 1.9e-129 431.9 4.1 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 ETS82579.1 - 2.3e-82 276.6 19.0 2.3e-82 276.6 19.0 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV COG2 PF06148.11 ETS82579.1 - 0.11 12.5 6.2 0.14 12.2 2.0 2.9 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.11 ETS82579.1 - 0.19 12.2 2.8 1.2 9.6 0.0 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF416 PF04222.12 ETS82579.1 - 0.37 10.2 7.0 0.94 8.9 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF416) Lactamase_B_2 PF12706.7 ETS82580.1 - 8e-24 84.3 0.0 3.3e-22 79.0 0.0 2.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ETS82580.1 - 4.2e-09 36.5 0.0 6.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ETS82580.1 - 0.006 16.6 0.2 0.064 13.3 0.0 2.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily fn3_3 PF14686.6 ETS82581.1 - 7.1e-26 89.8 0.7 2.1e-25 88.3 0.7 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 ETS82581.1 - 1.6e-21 76.9 0.1 3.2e-21 75.9 0.1 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III CarboxypepD_reg PF13620.6 ETS82581.1 - 0.0015 18.8 0.6 0.0053 17.0 0.2 2.2 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DAO PF01266.24 ETS82582.1 - 3.8e-56 191.2 4.3 4.3e-56 191.0 4.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS82582.1 - 0.00052 20.2 0.4 0.0013 19.0 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS82582.1 - 0.0082 15.4 0.0 0.17 11.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HTH_Tnp_IS1 PF12759.7 ETS82582.1 - 0.016 14.8 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 InsA C-terminal domain Mqo PF06039.15 ETS82582.1 - 0.027 13.0 0.0 0.78 8.2 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) DUF4031 PF13223.6 ETS82582.1 - 0.13 12.5 0.1 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4031) BetR PF08667.10 ETS82582.1 - 0.18 11.8 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 BetR domain DUF2415 PF10313.9 ETS82583.1 - 6.8e-13 48.3 0.0 1.6e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 ETS82583.1 - 8.8e-05 22.7 0.0 0.83 10.0 0.0 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS82583.1 - 0.11 11.5 0.1 12 4.8 0.0 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MMS1_N PF10433.9 ETS82583.1 - 0.13 10.9 0.0 0.23 10.0 0.0 1.4 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.32 ETS82583.1 - 2.8 8.9 8.1 7.2 7.7 0.0 4.5 6 1 0 6 6 6 0 WD domain, G-beta repeat HSP70 PF00012.20 ETS82584.1 - 6.3e-266 883.3 16.0 7.2e-266 883.1 16.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ETS82584.1 - 3.2e-14 52.5 3.7 4.8e-12 45.3 0.8 2.4 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 ETS82584.1 - 0.00084 19.1 0.1 0.0027 17.5 0.1 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Big_3_4 PF13754.6 ETS82584.1 - 0.055 13.2 0.0 4.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function SRP_SPB PF02978.19 ETS82584.1 - 0.087 13.4 0.1 0.84 10.3 0.0 2.3 2 0 0 2 2 2 0 Signal peptide binding domain EcoR124_C PF12008.8 ETS82584.1 - 0.79 9.3 7.5 1.7 8.2 7.5 1.5 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal DUF4363 PF14276.6 ETS82584.1 - 1.4 9.0 5.7 3 8.0 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Cu-oxidase_3 PF07732.15 ETS82585.1 - 3.7e-43 146.3 5.0 3e-42 143.4 1.0 3.3 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ETS82585.1 - 1.9e-39 134.5 11.6 5.3e-36 123.4 2.9 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 ETS82585.1 - 1.4e-28 100.0 0.0 1.9e-27 96.4 0.0 2.7 3 1 0 3 3 3 1 Multicopper oxidase SRP68 PF16969.5 ETS82586.1 - 5.3e-199 662.8 16.0 6.1e-199 662.7 16.0 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 DUF4699 PF15770.5 ETS82586.1 - 0.02 14.7 2.3 0.057 13.2 2.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) PPR PF01535.20 ETS82587.1 - 2e-15 55.9 1.3 0.0023 18.1 0.0 7.1 7 0 0 7 7 7 3 PPR repeat PPR_2 PF13041.6 ETS82587.1 - 4.8e-14 52.3 1.9 0.01 16.0 0.0 6.2 5 1 1 6 6 6 4 PPR repeat family PPR_3 PF13812.6 ETS82587.1 - 1.5e-05 24.9 0.0 0.39 10.8 0.0 4.4 2 2 2 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 ETS82587.1 - 6.9e-05 22.3 0.0 0.65 9.3 0.0 4.2 2 1 2 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ETS82587.1 - 0.00021 20.9 0.4 0.1 12.4 0.0 3.0 3 0 0 3 3 3 1 PPR repeat TPR_19 PF14559.6 ETS82587.1 - 0.00023 21.6 0.1 3.1 8.4 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ETS82587.1 - 0.0012 18.9 0.6 0.087 13.1 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ETS82587.1 - 0.004 17.9 2.6 8 7.6 0.0 5.6 6 0 0 6 6 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 ETS82587.1 - 0.015 15.3 0.6 1.2 9.3 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 ETS82587.1 - 0.037 14.7 0.0 0.28 11.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ETS82587.1 - 0.04 14.6 0.4 2.3 9.1 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ETS82587.1 - 0.043 14.1 1.4 5.7 7.3 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Imm30 PF15565.6 ETS82587.1 - 0.095 12.8 0.8 1.2 9.2 0.1 3.0 3 0 0 3 3 3 0 Immunity protein 30 TPR_2 PF07719.17 ETS82587.1 - 2.9 8.2 6.7 0.56 10.5 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2046 PF09755.9 ETS82588.1 - 0.00026 20.3 2.7 0.0043 16.3 0.3 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) Pox_A_type_inc PF04508.12 ETS82588.1 - 0.00034 20.3 1.5 0.001 18.8 1.5 1.8 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Atg14 PF10186.9 ETS82588.1 - 0.029 13.5 3.9 0.033 13.3 0.2 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DMSP_lyase PF16867.5 ETS82588.1 - 0.089 12.4 0.4 0.089 12.4 0.4 1.7 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase SlyX PF04102.12 ETS82588.1 - 0.12 13.0 11.6 2.5 8.8 4.0 2.4 2 0 0 2 2 2 0 SlyX TSC22 PF01166.18 ETS82588.1 - 7.9 6.9 10.4 0.073 13.4 1.7 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family eIF3g PF12353.8 ETS82590.1 - 1.1e-45 155.0 6.0 1.7e-45 154.4 6.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 ETS82590.1 - 2e-15 56.4 0.1 2e-15 56.4 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 ETS82590.1 - 0.017 15.4 0.1 0.033 14.5 0.1 1.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 RRM_occluded PF16842.5 ETS82590.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif FAD_oxidored PF12831.7 ETS82591.1 - 0.052 12.9 0.4 0.059 12.7 0.4 1.0 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF4811 PF16069.5 ETS82591.1 - 0.074 12.9 0.2 0.074 12.9 0.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4811) Synaphin PF05835.12 ETS82591.1 - 0.14 12.5 13.0 0.62 10.3 0.8 2.1 2 0 0 2 2 2 0 Synaphin protein SMBP PF16785.5 ETS82591.1 - 0.17 12.1 0.4 0.17 12.1 0.4 2.1 2 0 0 2 2 2 0 Small metal-binding protein Presenilin PF01080.17 ETS82591.1 - 4.3 6.0 6.3 5.1 5.7 6.3 1.1 1 0 0 1 1 1 0 Presenilin PEMT PF04191.13 ETS82592.1 - 2.8e-59 198.1 8.5 1.2e-36 125.3 1.1 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 ETS82592.1 - 0.0024 17.7 0.0 0.0098 15.7 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 ETS82592.1 - 0.038 14.5 0.0 1.1 9.8 0.0 2.4 1 1 0 1 1 1 0 SKICH domain Aldolase_II PF00596.21 ETS82593.1 - 2.2e-45 154.9 0.0 2.8e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Methyltr_RsmB-F PF01189.17 ETS82594.1 - 1.7e-31 109.4 0.0 2.2e-24 86.2 0.0 3.0 3 0 0 3 3 3 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 ETS82594.1 - 0.017 15.3 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase GTP1_OBG PF01018.22 ETS82595.1 - 4.6e-40 136.7 0.6 3.9e-29 101.3 2.4 2.6 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.23 ETS82595.1 - 4.5e-24 84.7 0.0 8.1e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ETS82595.1 - 2.7e-08 33.5 0.0 7.1e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 ETS82595.1 - 0.057 12.4 0.0 0.38 9.7 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 ETS82595.1 - 0.068 13.7 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Arf PF00025.21 ETS82595.1 - 0.077 12.4 0.0 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family Prok-JAB PF14464.6 ETS82595.1 - 0.41 10.4 3.4 0.49 10.2 1.8 1.9 2 0 0 2 2 2 0 Prokaryotic homologs of the JAB domain APG6_N PF17675.1 ETS82597.1 - 0.0048 17.4 12.3 0.0048 17.4 12.3 5.1 2 1 2 4 4 4 1 Apg6 coiled-coil region ABC_tran_CTD PF16326.5 ETS82597.1 - 0.0065 16.7 2.8 0.0065 16.7 2.8 6.6 4 3 3 7 7 7 1 ABC transporter C-terminal domain DUF948 PF06103.11 ETS82597.1 - 0.83 10.0 13.8 2.3 8.6 1.0 4.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4239 PF14023.6 ETS82597.1 - 1.5 8.5 9.8 1.1 9.0 1.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) Baculo_PEP_C PF04513.12 ETS82597.1 - 2.7 8.0 11.9 5.8 7.0 1.6 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_pol_Rpb5_C PF01191.19 ETS82598.1 - 1.4e-31 108.1 0.2 2.5e-31 107.4 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 ETS82598.1 - 9.3e-26 90.2 0.1 1.5e-25 89.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain p450 PF00067.22 ETS82599.1 - 1e-18 67.4 0.0 1.7e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 TFCD_C PF12612.8 ETS82601.1 - 7.8e-23 81.3 1.8 2.6e-22 79.6 0.2 2.9 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal Vac14_Fab1_bd PF12755.7 ETS82601.1 - 0.044 14.4 0.0 0.29 11.8 0.0 2.4 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 ETS82601.1 - 0.12 12.7 7.3 0.36 11.2 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 ETS82601.1 - 5.4 7.5 13.5 0.82 10.1 0.1 5.6 6 1 0 6 6 6 0 HEAT repeats Glyco_hydro_76 PF03663.14 ETS82602.1 - 3.6e-40 138.6 20.3 1.9e-39 136.2 20.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 ETS82602.1 - 1.6e-08 34.0 4.2 0.00017 20.8 0.1 3.7 2 1 2 4 4 4 2 Glycosyl Hydrolase Family 88 Acetyltransf_10 PF13673.7 ETS82603.1 - 1.3e-11 44.5 0.0 2.5e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS82603.1 - 4.8e-08 33.2 0.0 9.1e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS82603.1 - 8.2e-08 32.6 0.0 1.4e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETS82603.1 - 0.00018 21.6 0.0 0.005 16.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS82603.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.7 ETS82603.1 - 0.18 12.5 0.7 7 7.3 0.7 2.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Cutinase PF01083.22 ETS82604.1 - 1.5e-44 152.1 0.9 2.5e-44 151.4 0.3 1.6 2 0 0 2 2 2 1 Cutinase PE-PPE PF08237.11 ETS82604.1 - 6.8e-05 22.5 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 ETS82604.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Maff2 PF12750.7 ETS82604.1 - 0.037 13.9 0.8 0.45 10.4 0.3 2.5 2 0 0 2 2 2 0 Maff2 family DUF2974 PF11187.8 ETS82604.1 - 0.18 11.3 0.1 0.29 10.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF4210 PF13915.6 ETS82605.1 - 2.6e-33 114.4 0.1 7.5e-33 112.9 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 ETS82605.1 - 1.9e-22 79.2 0.5 3.8e-22 78.2 0.5 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.11 ETS82606.1 - 0.29 11.2 48.5 1.8e+04 -8.2 48.5 2.5 1 1 0 1 1 1 0 rRNA processing RhoGAP PF00620.27 ETS82607.1 - 6.9e-46 155.8 0.0 6.9e-46 155.8 0.0 3.0 3 1 1 4 4 4 1 RhoGAP domain LIM PF00412.22 ETS82607.1 - 1.2e-14 54.3 17.7 2.3e-09 37.3 1.7 2.4 2 0 0 2 2 2 2 LIM domain GCP_N_terminal PF17681.1 ETS82607.1 - 0.041 13.5 0.3 0.085 12.5 0.3 1.5 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal KASH_CCD PF14662.6 ETS82607.1 - 0.13 12.0 20.2 0.75 9.6 20.2 2.0 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4407 PF14362.6 ETS82607.1 - 2.1 7.6 9.0 5.7 6.2 8.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) IFT20 PF14931.6 ETS82607.1 - 2.4 8.4 10.6 0.33 11.1 5.0 2.2 1 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 CENP-F_leu_zip PF10473.9 ETS82607.1 - 3.1 7.8 19.1 2.1 8.4 4.0 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_head PF00063.21 ETS82608.1 - 0.31 9.2 0.9 0.41 8.8 0.9 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) Peptidase_C12 PF01088.21 ETS82609.1 - 2.3e-55 187.6 0.0 2.7e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Abhydrolase_1 PF00561.20 ETS82611.1 - 2e-19 70.3 0.0 8.2e-19 68.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS82611.1 - 9e-16 57.9 0.0 1e-14 54.4 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS82611.1 - 1.2e-11 45.7 0.0 6.5e-11 43.3 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 ETS82611.1 - 9.6e-05 21.8 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 ETS82611.1 - 0.00035 20.3 0.0 0.00065 19.4 0.0 1.4 1 0 0 1 1 1 1 Putative esterase LIDHydrolase PF10230.9 ETS82611.1 - 0.019 14.6 0.0 0.049 13.2 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 ETS82611.1 - 0.031 13.2 0.0 0.054 12.4 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 ETS82611.1 - 0.048 13.4 0.0 0.73 9.6 0.0 2.4 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 ETS82611.1 - 0.089 12.6 0.0 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family Thioesterase PF00975.20 ETS82611.1 - 0.097 12.8 0.1 0.25 11.4 0.1 1.8 1 1 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.11 ETS82611.1 - 0.12 12.2 0.0 19 5.1 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase PF07224.11 ETS82611.1 - 0.17 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Lipase_3 PF01764.25 ETS82611.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) OB_NTP_bind PF07717.16 ETS82612.1 - 5.8e-22 77.8 0.0 1.2e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 ETS82612.1 - 6.6e-22 77.8 0.1 6.6e-22 77.8 0.1 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ETS82612.1 - 2.1e-14 53.8 0.0 5.6e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 ETS82612.1 - 7.9e-11 42.2 1.0 1.7e-10 41.1 1.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 ETS82612.1 - 3.8e-07 30.0 0.1 7.7e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 ETS82612.1 - 7.5e-05 21.9 0.0 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 ETS82612.1 - 9e-05 22.8 0.0 0.00022 21.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ETS82612.1 - 0.002 17.9 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ETS82612.1 - 0.011 16.1 0.1 0.026 14.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ETS82612.1 - 0.013 16.0 0.2 0.57 10.7 0.1 2.8 1 1 1 2 2 2 0 ABC transporter AAA_14 PF13173.6 ETS82612.1 - 0.025 14.6 0.3 0.25 11.4 0.3 2.2 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 ETS82612.1 - 0.04 13.2 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Herpes_ori_bp PF02399.15 ETS82612.1 - 0.13 10.3 0.0 0.22 9.5 0.0 1.3 1 0 0 1 1 1 0 Origin of replication binding protein SRP54 PF00448.22 ETS82612.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Pmp3 PF01679.17 ETS82613.1 - 1.2e-19 70.2 12.2 1.6e-19 69.8 12.2 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Spt20 PF12090.8 ETS82613.1 - 0.28 10.8 8.9 0.32 10.6 8.9 1.1 1 0 0 1 1 1 0 Spt20 family Lin-8 PF03353.15 ETS82613.1 - 1.8 8.1 5.1 2 7.9 5.1 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CAF20 PF17052.5 ETS82614.1 - 0.0089 16.2 3.2 0.4 10.8 2.7 2.8 2 0 0 2 2 2 2 Cap associated factor SUV3_C PF12513.8 ETS82616.1 - 2.3e-18 65.8 1.0 6.6e-18 64.4 1.0 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 ETS82616.1 - 5.8e-15 54.9 0.3 1.2e-14 53.9 0.3 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 ETS82616.1 - 1.4e-08 35.0 0.0 3.6e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Synaptobrevin PF00957.21 ETS82617.1 - 9.3e-33 111.9 1.4 1.3e-32 111.4 1.4 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 ETS82617.1 - 3.4e-25 87.9 0.0 6.6e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Holin_BlyA PF05102.12 ETS82617.1 - 0.21 11.6 4.6 0.39 10.7 4.6 1.3 1 0 0 1 1 1 0 holin, BlyA family GATA-N PF05349.12 ETS82618.1 - 0.077 13.3 0.9 0.097 13.0 0.9 1.3 1 1 0 1 1 1 0 GATA-type transcription activator, N-terminal adh_short PF00106.25 ETS82619.1 - 2.7e-13 49.8 0.0 5.5e-12 45.5 0.0 2.7 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ETS82619.1 - 1.1e-05 25.4 0.3 3e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 ETS82619.1 - 3.1e-05 23.7 0.0 0.00019 21.1 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ETS82619.1 - 0.00011 21.8 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2570 PF10828.8 ETS82619.1 - 0.00069 19.4 0.5 0.0013 18.6 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) GDP_Man_Dehyd PF16363.5 ETS82619.1 - 0.36 10.2 2.4 0.82 9.0 0.0 2.4 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase CENP-Q PF13094.6 ETS82619.1 - 4.1 7.6 11.1 6.2 7.0 11.1 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit G-patch PF01585.23 ETS82620.1 - 3.4e-10 39.6 0.5 5.7e-10 38.9 0.5 1.4 1 0 0 1 1 1 1 G-patch domain Sec1 PF00995.23 ETS82621.1 - 1.6e-115 387.6 0.0 1.8e-115 387.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DSPc PF00782.20 ETS82622.1 - 4.8e-15 55.6 0.0 5.7e-14 52.1 0.1 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain polyprenyl_synt PF00348.17 ETS82622.1 - 0.0032 16.5 0.1 0.0046 16.1 0.1 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Init_tRNA_PT PF04179.12 ETS82622.1 - 0.0084 16.4 0.1 0.036 14.4 0.1 1.9 1 1 0 1 1 1 1 Rit1 DUSP-like domain Spo7 PF03907.13 ETS82623.1 - 2e-93 312.0 0.0 4.9e-93 310.6 0.0 1.6 1 1 1 2 2 2 1 Spo7-like protein TMEM247 PF15444.6 ETS82623.1 - 5.8 6.9 5.3 35 4.4 0.2 2.2 2 0 0 2 2 2 0 Transmembrane protein 247 Endomucin PF07010.12 ETS82624.1 - 0.039 13.9 51.6 0.026 14.5 22.3 2.4 2 0 0 2 2 2 0 Endomucin PAN_4 PF14295.6 ETS82624.1 - 0.056 13.4 0.3 0.13 12.2 0.3 1.6 1 0 0 1 1 1 0 PAN domain GATA PF00320.27 ETS82625.1 - 7.3e-15 54.3 2.6 1.3e-14 53.5 2.6 1.4 1 0 0 1 1 1 1 GATA zinc finger Golgin_A5 PF09787.9 ETS82625.1 - 0.012 15.1 10.7 0.02 14.4 10.7 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 TF_Zn_Ribbon PF08271.12 ETS82625.1 - 0.056 13.0 0.4 0.11 12.0 0.4 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding AAA_23 PF13476.6 ETS82625.1 - 0.19 12.2 4.8 0.31 11.5 4.8 1.3 1 0 0 1 1 1 0 AAA domain ArfGap PF01412.18 ETS82625.1 - 0.3 11.2 0.1 0.3 11.2 0.1 2.3 2 1 1 3 3 3 0 Putative GTPase activating protein for Arf CENP-F_leu_zip PF10473.9 ETS82625.1 - 0.54 10.3 18.0 0.31 11.0 3.9 2.5 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tweety PF04906.13 ETS82625.1 - 0.7 8.5 2.2 0.81 8.3 0.1 1.8 1 1 1 2 2 2 0 Tweety Fmp27_WPPW PF10359.9 ETS82625.1 - 1.1 8.0 11.0 1.8 7.4 11.0 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Cnn_1N PF07989.11 ETS82625.1 - 3.3 7.9 18.1 0.57 10.4 0.2 3.7 2 1 1 3 3 2 0 Centrosomin N-terminal motif 1 XhlA PF10779.9 ETS82625.1 - 3.7 7.8 11.2 0.42 10.9 1.0 2.8 1 1 1 3 3 3 0 Haemolysin XhlA ADIP PF11559.8 ETS82625.1 - 6.2 6.9 19.8 13 5.8 5.5 2.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding FemAB PF02388.16 ETS82625.1 - 6.7 5.5 7.5 9.9 4.9 7.5 1.2 1 0 0 1 1 1 0 FemAB family KxDL PF10241.9 ETS82625.1 - 9.7 6.6 12.0 3.1 8.2 6.4 2.5 2 1 1 3 3 2 0 Uncharacterized conserved protein KH_8 PF17903.1 ETS82626.1 - 8.5e-30 102.7 0.0 2.1e-29 101.4 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 ETS82626.1 - 0.014 15.2 0.0 0.039 13.8 0.0 1.8 1 0 0 1 1 1 0 KH domain Toast_rack_N PF17115.5 ETS82626.1 - 0.043 14.1 1.5 0.11 12.8 1.5 1.7 1 0 0 1 1 1 0 N-terminal domain of toast_rack, DUF2154 Bystin PF05291.11 ETS82627.1 - 2e-126 421.2 0.0 2.5e-126 420.9 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF383 PF04063.14 ETS82628.1 - 5.8e-65 218.5 0.2 4.6e-64 215.6 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 ETS82628.1 - 5e-23 80.7 1.1 1.2e-22 79.5 1.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Sugar_tr PF00083.24 ETS82629.1 - 1.1e-51 176.1 21.1 1.7e-51 175.5 21.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS82629.1 - 8.3e-21 74.3 25.7 8.3e-21 74.3 25.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily NTP_transf_9 PF04248.12 ETS82630.1 - 9e-32 108.8 2.0 1e-31 108.7 2.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) FMN_dh PF01070.18 ETS82631.1 - 2.6e-121 404.9 0.3 3.2e-121 404.6 0.3 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ETS82631.1 - 7.6e-24 83.7 0.1 1.6e-23 82.6 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 ETS82631.1 - 2e-07 30.5 0.1 4.4e-07 29.4 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 ETS82631.1 - 2.1e-05 23.7 1.2 0.00044 19.4 0.1 2.5 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 ETS82631.1 - 0.00078 18.9 0.5 0.0015 18.0 0.4 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 ETS82631.1 - 0.0082 15.6 0.6 0.24 10.8 0.1 2.3 1 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 ETS82631.1 - 0.023 14.0 0.1 4.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 ETS82631.1 - 0.1 11.7 0.1 1.7 7.7 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF561) G3P_antiterm PF04309.12 ETS82631.1 - 0.16 11.4 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Cullin PF00888.22 ETS82632.1 - 1.9e-194 647.8 9.7 2.6e-194 647.3 9.7 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ETS82632.1 - 4.4e-27 93.9 2.8 1.6e-26 92.1 2.8 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 ETS82632.1 - 0.022 15.3 1.7 0.053 14.0 0.6 2.3 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF1803 PF08820.10 ETS82632.1 - 0.1 12.6 4.0 8.1 6.5 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1803) FAM194 PF14977.6 ETS82632.1 - 0.57 9.5 4.5 0.64 9.3 0.9 2.8 3 0 0 3 3 3 0 FAM194 protein 7tm_3 PF00003.22 ETS82634.1 - 0.00027 20.7 5.1 0.0018 18.1 4.7 2.0 1 1 1 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Phage_holin_3_6 PF07332.11 ETS82634.1 - 0.019 15.0 1.1 4.8 7.3 0.1 3.3 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2781 PF10914.8 ETS82634.1 - 0.046 14.1 5.5 1.1 9.7 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2781) Sec23_BS PF08033.12 ETS82634.1 - 0.062 14.1 0.1 0.2 12.4 0.1 1.8 2 0 0 2 2 2 0 Sec23/Sec24 beta-sandwich domain COX2-transmemb PF09125.10 ETS82634.1 - 0.18 11.6 0.2 0.48 10.2 0.2 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane Virul_fac_BrkB PF03631.15 ETS82634.1 - 1 8.9 7.4 0.68 9.5 2.4 2.3 1 1 0 2 2 2 0 Virulence factor BrkB Glycos_transf_4 PF00953.21 ETS82635.1 - 8e-32 110.4 11.1 8e-32 110.4 11.1 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 4 PHD PF00628.29 ETS82636.1 - 1.9e-07 30.9 7.7 3.5e-07 30.0 7.7 1.4 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 ETS82636.1 - 1.2e-06 29.0 0.0 3.2e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 SET domain NAT PF04768.13 ETS82637.1 - 2.6e-47 160.7 0.0 4.1e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase HSP70 PF00012.20 ETS82638.1 - 2.1e-171 571.1 2.8 3e-171 570.7 2.8 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ETS82638.1 - 1.6e-12 46.9 0.0 5.2e-11 41.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Ketoacyl-synt_C PF02801.22 ETS82638.1 - 0.092 12.8 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain BLOC1S3 PF15753.5 ETS82638.1 - 0.21 11.7 6.8 0.86 9.7 5.9 2.3 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Apolipoprotein PF01442.18 ETS82638.1 - 0.28 11.0 16.4 0.14 12.0 12.8 2.3 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain WD40 PF00400.32 ETS82641.1 - 3e-10 40.5 0.4 0.0058 17.5 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS82641.1 - 0.0034 17.6 0.0 19 5.6 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS82641.1 - 0.0099 14.9 0.0 0.51 9.3 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyco_hydro_6 PF01341.17 ETS82642.1 - 1.2e-103 347.1 0.5 1.6e-103 346.7 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 THDPS_N PF14790.6 ETS82642.1 - 0.044 13.6 0.1 0.073 12.9 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal adh_short_C2 PF13561.6 ETS82643.1 - 5.2e-57 193.1 3.4 5.9e-57 192.9 3.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS82643.1 - 1.1e-40 139.2 3.0 1.4e-40 138.9 3.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS82643.1 - 3.3e-13 49.9 0.9 4.9e-13 49.4 0.9 1.2 1 0 0 1 1 1 1 KR domain DLP_helical PF18709.1 ETS82643.1 - 0.054 12.7 0.1 0.083 12.1 0.1 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain tRNA-synt_1d PF00750.19 ETS82643.1 - 0.057 12.4 0.0 0.079 11.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (R) ADH_N PF08240.12 ETS82644.1 - 3.5e-30 104.1 3.7 4.2e-30 103.8 0.8 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS82644.1 - 2.5e-20 72.8 0.0 5.2e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS82644.1 - 5.5e-09 35.8 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ETS82644.1 - 4.3e-06 27.8 0.0 9.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ETS82644.1 - 1.8e-05 24.1 0.5 3.2e-05 23.3 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ETS82644.1 - 0.00018 20.4 0.0 0.00026 19.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 ETS82644.1 - 0.00077 18.8 0.8 0.0021 17.4 0.4 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 ETS82644.1 - 0.0082 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ETS82644.1 - 0.011 16.2 0.0 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 ETS82644.1 - 0.014 15.4 0.2 0.058 13.5 0.2 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ETS82644.1 - 0.025 14.2 0.1 0.038 13.6 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 ETS82644.1 - 0.049 14.2 0.9 0.098 13.2 0.3 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DapB_N PF01113.20 ETS82644.1 - 0.087 12.9 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PALP PF00291.25 ETS82644.1 - 0.088 12.2 1.2 0.18 11.2 0.5 1.8 1 1 1 2 2 2 0 Pyridoxal-phosphate dependent enzyme 2-Hacid_dh_C PF02826.19 ETS82644.1 - 0.19 11.1 0.1 0.34 10.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PRK PF00485.18 ETS82645.1 - 7.6e-11 42.1 0.0 1e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Cytidylate_kin PF02224.18 ETS82645.1 - 2.4e-06 27.4 0.1 5.5e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Cytidylate kinase AAA_18 PF13238.6 ETS82645.1 - 2.6e-06 28.0 0.0 7.5e-06 26.5 0.0 1.8 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 ETS82645.1 - 8.6e-06 26.0 1.1 4.2e-05 23.7 1.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS82645.1 - 4.3e-05 24.0 0.0 0.00013 22.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 ETS82645.1 - 7.7e-05 22.1 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.29 ETS82645.1 - 0.00014 22.3 0.0 0.00024 21.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS82645.1 - 0.00047 20.4 0.0 0.00079 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ETS82645.1 - 0.0013 18.7 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF3987 PF13148.6 ETS82645.1 - 0.0015 17.6 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) NB-ARC PF00931.22 ETS82645.1 - 0.0016 17.7 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain KTI12 PF08433.10 ETS82645.1 - 0.002 17.7 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 APS_kinase PF01583.20 ETS82645.1 - 0.0044 16.9 0.0 0.014 15.3 0.0 1.8 2 1 0 2 2 2 1 Adenylylsulphate kinase AAA_17 PF13207.6 ETS82645.1 - 0.0053 17.2 0.0 0.018 15.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 ETS82645.1 - 0.0059 16.3 0.9 0.021 14.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 ETS82645.1 - 0.0069 16.6 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 ETS82645.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NTPase_1 PF03266.15 ETS82645.1 - 0.017 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 NTPase RuvB_N PF05496.12 ETS82645.1 - 0.018 14.8 0.1 0.058 13.1 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 ETS82645.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Thymidylate_kin PF02223.17 ETS82645.1 - 0.019 14.7 0.0 0.75 9.4 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase AAA_24 PF13479.6 ETS82645.1 - 0.02 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ETS82645.1 - 0.025 14.6 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 ETS82645.1 - 0.026 15.1 0.0 0.097 13.2 0.0 1.5 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 ETS82645.1 - 0.027 14.9 0.0 0.046 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 ETS82645.1 - 0.031 14.2 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Cytidylate_kin2 PF13189.6 ETS82645.1 - 0.035 14.2 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family SKI PF01202.22 ETS82645.1 - 0.041 14.0 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase AAA_11 PF13086.6 ETS82645.1 - 0.042 13.6 0.0 0.062 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ETS82645.1 - 0.047 13.4 0.5 0.13 12.1 0.0 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 ETS82645.1 - 0.064 13.2 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 ETS82645.1 - 0.08 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 ETS82645.1 - 0.084 13.2 0.1 0.11 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 ETS82645.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 ETS82645.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain adh_short_C2 PF13561.6 ETS82646.1 - 3.3e-55 187.2 0.9 4.3e-55 186.8 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS82646.1 - 5.2e-39 133.7 0.3 7e-39 133.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS82646.1 - 1.2e-12 48.1 1.0 1.5e-12 47.8 1.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS82646.1 - 0.00053 19.5 0.5 0.0012 18.4 0.5 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ETS82646.1 - 0.0011 18.2 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ETS82646.1 - 0.016 14.6 0.1 0.03 13.7 0.1 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ETS82646.1 - 0.057 12.4 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sugar_tr PF00083.24 ETS82647.1 - 5.6e-130 434.2 22.8 7e-130 433.9 22.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS82647.1 - 1e-24 87.2 43.4 1.8e-16 60.1 20.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 ETS82648.1 - 5.8e-24 84.6 0.0 9.6e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS82648.1 - 6.6e-08 32.6 7.2 1.1e-07 31.9 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 ETS82648.1 - 0.047 13.8 0.2 0.096 12.9 0.2 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain Aldo_ket_red PF00248.21 ETS82649.1 - 2.8e-44 151.5 0.0 3.8e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_28 PF13518.6 ETS82649.1 - 0.052 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Sld5 PF05916.11 ETS82650.1 - 3.8e-28 98.1 0.0 5.5e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein SNF2_N PF00176.23 ETS82652.1 - 4.5e-64 216.4 0.1 1e-63 215.2 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS82652.1 - 1.2e-21 77.1 0.0 5.3e-21 75.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS82652.1 - 2.8e-07 30.7 0.0 7.8e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ETS82652.1 - 1.6e-05 24.3 0.0 1.6e-05 24.3 0.0 2.1 3 0 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 ETS82652.1 - 0.0012 18.0 0.0 0.014 14.6 0.0 2.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 ETS82652.1 - 0.0023 17.6 0.2 0.0076 15.9 0.0 2.0 2 1 0 2 2 2 1 SWI2/SNF2 ATPase DUF2239 PF09998.9 ETS82652.1 - 0.082 12.7 3.9 0.54 10.0 0.4 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) Latarcin PF10279.9 ETS82652.1 - 0.69 10.4 7.4 0.86 10.0 0.3 2.9 2 0 0 2 2 2 0 Latarcin precursor AT_hook PF02178.19 ETS82652.1 - 4.4 7.5 19.3 0.025 14.4 1.9 3.1 2 0 0 2 2 2 0 AT hook motif DUF1682 PF07946.14 ETS82652.1 - 4.7 6.3 10.2 45 3.1 9.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) TFIIA_gamma_N PF02268.16 ETS82653.1 - 1.2e-24 86.0 0.3 1.7e-24 85.5 0.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 ETS82653.1 - 1.3e-23 82.8 2.0 2.2e-23 82.1 2.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit HHH_4 PF14490.6 ETS82653.1 - 0.058 13.4 0.0 0.21 11.6 0.0 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix containing domain EamA PF00892.20 ETS82654.1 - 6.5e-05 23.1 12.8 0.0018 18.4 12.8 2.1 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 ETS82654.1 - 0.058 13.4 1.9 0.089 12.8 1.9 1.3 1 0 0 1 1 1 0 Putative transmembrane family 234 Voltage_CLC PF00654.20 ETS82655.1 - 7.5e-88 295.1 30.5 7.5e-88 295.1 30.5 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 ETS82655.1 - 2.2e-12 47.2 0.1 2.6e-06 27.8 0.1 2.6 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.23 ETS82656.1 - 8.1e-13 48.5 2.1 8.8e-13 48.3 0.6 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ETS82656.1 - 5.6e-05 23.5 1.8 8.2e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 ETS82656.1 - 0.052 13.6 0.2 0.096 12.8 0.2 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region DUF4765 PF15962.5 ETS82656.1 - 0.053 11.5 0.0 0.064 11.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4765) Pol_alpha_B_N PF08418.10 ETS82656.1 - 0.1 12.6 2.0 0.12 12.3 2.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal LRR_9 PF14580.6 ETS82657.1 - 1.9e-51 174.0 0.4 2.6e-51 173.6 0.0 1.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 ETS82657.1 - 1.7e-05 24.5 13.6 0.00032 20.4 3.6 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ETS82657.1 - 0.00079 19.8 10.9 0.0026 18.1 2.7 3.4 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) DUF4349 PF14257.6 ETS82657.1 - 0.048 13.1 0.4 0.048 13.1 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) GA PF01468.17 ETS82657.1 - 0.13 12.6 0.1 0.41 11.0 0.1 1.8 1 0 0 1 1 1 0 GA module PspB PF06667.12 ETS82657.1 - 5.8 7.1 5.5 0.82 9.8 1.1 1.9 2 0 0 2 2 2 0 Phage shock protein B GATase PF00117.28 ETS82658.1 - 2.1e-09 37.4 0.0 3.5e-09 36.7 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GPI-anchored PF10342.9 ETS82659.1 - 2e-05 25.2 0.5 3.4e-05 24.5 0.5 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Lactonase PF10282.9 ETS82660.1 - 1.6e-83 280.8 0.0 2e-83 280.5 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Zn_clus PF00172.18 ETS82661.1 - 4.9e-09 36.2 7.9 4.9e-09 36.2 7.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_A4 PF01828.17 ETS82662.1 - 2.5e-57 193.7 12.9 2.5e-57 193.7 12.9 1.5 2 0 0 2 2 2 1 Peptidase A4 family Pec_lyase_C PF00544.19 ETS82663.1 - 6.6e-07 29.1 10.3 1.4e-05 24.8 10.3 2.3 1 1 0 1 1 1 1 Pectate lyase adh_short PF00106.25 ETS82665.1 - 5.5e-29 101.0 0.0 7.7e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS82665.1 - 9.1e-27 94.1 0.0 1.2e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS82665.1 - 0.018 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 KR domain FMO-like PF00743.19 ETS82666.1 - 2.9e-15 55.7 0.0 3.8e-14 52.0 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ETS82666.1 - 5.6e-11 42.5 0.0 1.4e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS82666.1 - 9.5e-09 34.9 0.0 1.3e-07 31.2 0.0 2.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS82666.1 - 1.4e-08 34.9 0.0 2.2e-06 27.7 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 ETS82666.1 - 2e-08 33.8 0.0 0.00047 19.4 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ETS82666.1 - 5.5e-08 32.8 0.9 0.00047 19.8 0.1 3.3 2 1 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS82666.1 - 1.2e-05 24.7 0.0 0.00075 18.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS82666.1 - 0.0082 15.4 0.0 0.02 14.1 0.0 1.6 1 0 0 1 1 1 1 Thi4 family AA_permease_2 PF13520.6 ETS82667.1 - 9e-64 215.9 44.8 1.1e-63 215.6 44.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS82667.1 - 5e-22 78.1 39.0 6.9e-22 77.7 39.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF5480 PF17576.2 ETS82667.1 - 0.046 13.7 0.0 0.22 11.5 0.0 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5480) Fungal_trans PF04082.18 ETS82668.1 - 3.6e-10 39.3 1.0 7.1e-10 38.4 1.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS82668.1 - 0.00055 20.0 12.8 0.00055 20.0 12.8 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1989 PF09347.10 ETS82669.1 - 4.4e-52 176.1 0.0 8.2e-52 175.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Polysacc_deac_1 PF01522.21 ETS82669.1 - 2e-17 63.2 0.0 3.2e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ETS82669.1 - 8.1e-07 28.9 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Beta-lactamase PF00144.24 ETS82670.1 - 4.1e-35 121.6 0.1 4.9e-35 121.3 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 ETS82670.1 - 0.015 14.8 0.0 0.028 13.8 0.0 1.6 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase p450 PF00067.22 ETS82671.1 - 3.5e-41 141.4 0.0 5.5e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS82673.1 - 1.5e-52 178.9 0.0 2.1e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ribonuc_L-PSP PF01042.21 ETS82674.1 - 1.2e-14 54.3 0.0 1.9e-14 53.7 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP NUMOD1 PF07453.13 ETS82674.1 - 0.18 12.1 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 NUMOD1 domain SMK-1 PF04802.15 ETS82676.1 - 1.3e-81 273.0 5.6 1.3e-81 273.0 5.6 2.1 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 RTP1_C1 PF10363.9 ETS82676.1 - 0.16 12.2 0.4 1.4 9.1 0.1 2.5 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Importin_rep_4 PF18808.1 ETS82676.1 - 0.16 12.3 0.4 15 5.9 0.0 2.8 2 0 0 2 2 2 0 Importin repeat ADH_zinc_N PF00107.26 ETS82677.1 - 4.7e-18 65.4 0.1 7.3e-18 64.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS82677.1 - 9.2e-08 33.2 0.0 1.9e-07 32.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 ETS82677.1 - 0.039 13.4 0.1 0.078 12.4 0.1 1.4 1 1 0 1 1 1 0 short chain dehydrogenase ADH_N PF08240.12 ETS82677.1 - 0.06 13.2 0.0 0.16 11.9 0.0 1.8 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Sulf_transp PF04143.14 ETS82678.1 - 5.4e-36 124.7 26.3 8.4e-36 124.1 26.3 1.3 1 0 0 1 1 1 1 Sulphur transport FAD_binding_4 PF01565.23 ETS82679.1 - 1.7e-12 47.3 0.0 3.1e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS82679.1 - 0.00011 22.2 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 ETS82680.1 - 1.5e-17 63.7 0.0 4e-12 46.0 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS82680.1 - 1.1e-05 25.1 0.0 0.0027 17.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS82680.1 - 6e-05 23.0 0.1 9.4e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 KR domain HET PF06985.11 ETS82681.1 - 0.0076 16.6 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribosomal_L34 PF00468.17 ETS82681.1 - 0.21 11.6 1.2 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L34 Dioxygenase_C PF00775.21 ETS82682.1 - 1.3e-06 28.0 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase SpaA PF17802.1 ETS82682.1 - 0.058 13.7 0.3 0.34 11.2 0.0 2.3 3 0 0 3 3 3 0 Prealbumin-like fold domain Ank_2 PF12796.7 ETS82683.1 - 3.9e-39 133.1 0.2 3.1e-12 46.9 0.0 6.2 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS82683.1 - 3.8e-27 94.3 2.0 4.9e-07 30.2 0.0 7.8 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS82683.1 - 1.2e-22 77.5 0.4 0.033 14.7 0.0 9.0 9 0 0 9 9 8 5 Ankyrin repeat Ank PF00023.30 ETS82683.1 - 1.4e-20 72.7 4.5 0.015 15.8 0.0 9.0 7 1 1 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 ETS82683.1 - 3.3e-18 65.5 2.0 0.0071 16.6 0.2 6.4 1 1 6 7 7 7 7 Ankyrin repeats (many copies) NACHT PF05729.12 ETS82683.1 - 9.8e-10 38.6 0.1 1.9e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 ETS82683.1 - 8.5e-07 28.5 0.2 5.3e-06 25.9 0.2 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_14 PF13173.6 ETS82683.1 - 6.6e-05 23.0 0.0 0.036 14.1 0.0 2.8 1 1 1 2 2 2 2 AAA domain ATPase_2 PF01637.18 ETS82683.1 - 0.0032 17.4 0.4 0.017 15.1 0.0 2.2 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 ETS82683.1 - 0.0077 16.5 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ETS82683.1 - 0.011 16.2 0.0 0.032 14.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ETS82683.1 - 0.018 15.4 0.0 0.057 13.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 ETS82683.1 - 0.059 12.5 0.2 0.12 11.5 0.2 1.5 1 0 0 1 1 1 0 NB-ARC domain MFS_1 PF07690.16 ETS82684.1 - 5.8e-33 114.3 28.6 5.8e-33 114.3 28.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS82684.1 - 1.1e-11 44.3 7.6 1.1e-11 44.3 7.6 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter Fungal_trans PF04082.18 ETS82685.1 - 1.5e-21 76.7 0.0 2.3e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS82685.1 - 1.7e-08 34.4 10.6 3.9e-08 33.3 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_membrane PF00664.23 ETS82686.1 - 2.1e-81 273.6 43.4 1.5e-41 142.9 14.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ETS82686.1 - 3e-62 209.1 0.0 3.5e-31 108.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 ETS82686.1 - 2.3e-13 50.1 0.0 0.00072 19.1 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ETS82686.1 - 1.5e-08 34.2 0.6 0.00027 20.6 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ETS82686.1 - 3.5e-07 30.3 0.0 0.01 15.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ETS82686.1 - 4.1e-07 30.3 0.1 0.12 12.7 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA PF00004.29 ETS82686.1 - 1.6e-06 28.6 0.9 1.2 9.6 0.0 4.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS82686.1 - 2.7e-06 27.9 0.6 0.18 12.2 0.0 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_24 PF13479.6 ETS82686.1 - 1.4e-05 24.9 0.1 0.02 14.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 ETS82686.1 - 2.7e-05 24.1 0.1 0.16 11.7 0.0 3.1 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 ETS82686.1 - 3.4e-05 23.4 0.0 0.31 10.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region ABC_ATPase PF09818.9 ETS82686.1 - 5.1e-05 22.3 0.7 0.04 12.7 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 ETS82686.1 - 7.6e-05 22.6 0.0 0.035 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 ETS82686.1 - 0.00014 21.7 0.1 1.5 8.5 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.6 ETS82686.1 - 0.00015 22.4 0.3 0.92 10.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ETS82686.1 - 0.00018 21.5 0.0 1.1 9.2 0.0 3.5 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 ETS82686.1 - 0.0017 18.5 2.7 2.7 8.3 0.5 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 ETS82686.1 - 0.0045 16.6 0.3 6.5 6.3 0.0 3.3 4 0 0 4 4 3 0 AAA domain AAA_33 PF13671.6 ETS82686.1 - 0.0046 17.1 0.1 5.4 7.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ETS82686.1 - 0.0053 17.3 0.0 2.9 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 ETS82686.1 - 0.0056 16.4 1.5 1.9 8.2 0.0 3.8 5 0 0 5 5 4 1 IstB-like ATP binding protein SRP54 PF00448.22 ETS82686.1 - 0.006 16.2 0.2 4.2 6.9 0.0 2.8 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain Rad17 PF03215.15 ETS82686.1 - 0.0066 16.4 0.0 0.58 10.0 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain ATP_bind_1 PF03029.17 ETS82686.1 - 0.012 15.4 0.0 0.71 9.6 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 ETS82686.1 - 0.025 14.8 0.0 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain MoeA_C PF03454.15 ETS82686.1 - 0.039 14.1 0.0 0.45 10.7 0.0 2.3 2 0 0 2 2 2 0 MoeA C-terminal region (domain IV) ATP-synt_ab PF00006.25 ETS82686.1 - 0.06 13.0 0.0 9.4 5.8 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 ETS82686.1 - 0.062 13.7 0.0 11 6.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Dala_Dala_lig_N PF01820.21 ETS82686.1 - 0.065 13.7 0.0 11 6.6 0.0 2.7 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus AAA_17 PF13207.6 ETS82686.1 - 0.096 13.1 0.4 15 6.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain TniB PF05621.11 ETS82686.1 - 0.099 12.0 0.0 30 3.9 0.0 3.4 4 0 0 4 4 4 0 Bacterial TniB protein Mg_chelatase PF01078.21 ETS82686.1 - 0.12 11.7 0.0 9.6 5.5 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PRK PF00485.18 ETS82686.1 - 0.13 12.0 0.1 18 5.0 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zn_clus PF00172.18 ETS82687.1 - 7.7e-08 32.3 10.3 1.3e-07 31.6 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rif1_N PF12231.8 ETS82687.1 - 0.081 11.9 0.3 11 4.9 0.0 2.2 2 0 0 2 2 2 0 Rap1-interacting factor 1 N terminal Tannase PF07519.11 ETS82688.1 - 6.6e-106 355.0 1.1 7.7e-106 354.8 1.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase COesterase PF00135.28 ETS82689.1 - 1.5e-21 76.9 0.0 2.9e-20 72.7 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family gpD PF02925.16 ETS82689.1 - 0.082 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage scaffolding protein D Abhydrolase_3 PF07859.13 ETS82689.1 - 0.092 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Fungal_trans PF04082.18 ETS82690.1 - 0.0035 16.4 2.2 0.0093 15.0 2.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain HgmA PF04209.13 ETS82691.1 - 1.3e-133 445.8 0.0 1.5e-133 445.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Glyco_hydro_18 PF00704.28 ETS82692.1 - 6.1e-44 151.0 13.4 6.1e-44 151.0 13.4 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.20 ETS82692.1 - 1.4e-11 44.2 0.0 0.00087 19.3 0.0 3.6 3 0 0 3 3 3 3 LysM domain Chitin_bind_1 PF00187.19 ETS82692.1 - 0.0001 22.7 8.4 0.0001 22.7 8.4 4.6 4 0 0 4 4 4 1 Chitin recognition protein Ank_2 PF12796.7 ETS82694.1 - 2.8e-27 95.1 0.0 6.8e-15 55.4 0.0 5.8 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS82694.1 - 2.3e-21 75.9 7.1 1.1e-06 29.0 0.0 8.1 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 ETS82694.1 - 1.7e-18 66.1 0.8 0.011 16.1 0.0 7.6 9 0 0 9 9 9 4 Ankyrin repeat Ank_3 PF13606.6 ETS82694.1 - 2e-16 58.4 1.3 0.00046 20.4 0.0 8.5 9 0 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 ETS82694.1 - 5.1e-16 58.5 2.9 0.00021 21.5 0.0 5.7 5 1 0 5 5 5 3 Ankyrin repeats (many copies) Helo_like_N PF17111.5 ETS82694.1 - 0.12 11.7 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins KapB PF08810.10 ETS82696.1 - 0.012 15.8 1.8 0.42 10.8 0.3 2.6 2 0 0 2 2 2 0 Kinase associated protein B Baculo_PEP_C PF04513.12 ETS82696.1 - 0.064 13.3 1.7 4.1 7.4 0.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4618 PF15397.6 ETS82696.1 - 0.13 11.7 5.7 0.41 10.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) OmpH PF03938.14 ETS82696.1 - 0.16 12.3 14.8 0.99 9.7 2.8 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) PhaP_Bmeg PF09602.10 ETS82696.1 - 0.18 11.8 6.0 0.15 12.0 1.9 2.3 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Phage_lysozyme2 PF18013.1 ETS82696.1 - 0.23 11.4 3.3 1.6 8.7 0.3 2.2 2 0 0 2 2 2 0 Phage tail lysozyme GGDEF PF00990.21 ETS82696.1 - 0.29 10.9 3.7 0.48 10.2 0.7 2.4 2 0 0 2 2 2 0 Diguanylate cyclase, GGDEF domain DUF4456 PF14644.6 ETS82696.1 - 0.31 10.7 11.9 0.95 9.1 10.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4456) DUF3584 PF12128.8 ETS82696.1 - 0.31 8.5 18.3 0.74 7.3 18.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Syntaxin-6_N PF09177.11 ETS82696.1 - 0.4 11.3 6.8 0.39 11.3 2.1 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Apolipoprotein PF01442.18 ETS82696.1 - 0.41 10.5 17.3 1.4 8.7 17.2 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 ETS82696.1 - 0.44 10.6 7.6 0.5 10.4 0.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) T3SS_basalb_I PF17001.5 ETS82696.1 - 0.49 11.0 5.2 0.45 11.2 0.9 2.8 2 1 1 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI ApoLp-III PF07464.11 ETS82696.1 - 0.78 9.8 6.8 3.4 7.8 0.9 2.5 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) OEP PF02321.18 ETS82696.1 - 1.9 8.3 14.1 0.25 11.1 1.7 3.3 2 1 1 3 3 3 0 Outer membrane efflux protein Phasin PF05597.11 ETS82696.1 - 2.3 8.2 10.9 7.3 6.6 2.9 2.8 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Prominin PF05478.11 ETS82696.1 - 4.9 5.0 4.7 6.1 4.7 4.7 1.1 1 0 0 1 1 1 0 Prominin DUF5339 PF17274.2 ETS82696.1 - 7 7.6 12.0 1.4 9.8 2.7 2.9 3 0 0 3 3 2 0 Family of unknown function (DUF5339) HET PF06985.11 ETS82697.1 - 9.3e-30 103.9 1.0 2e-29 102.8 1.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) B_lectin PF01453.24 ETS82698.1 - 4.4e-14 52.9 1.8 0.00085 19.8 0.1 4.8 2 1 2 5 5 5 4 D-mannose binding lectin HET PF06985.11 ETS82698.1 - 7.3e-09 36.1 8.5 7.3e-09 36.1 8.5 3.1 3 1 0 3 3 3 1 Heterokaryon incompatibility protein (HET) PQQ_3 PF13570.6 ETS82698.1 - 0.94 10.1 6.4 3 8.4 0.1 3.9 3 1 1 4 4 4 0 PQQ-like domain Glyco_tran_WecB PF03808.13 ETS82699.1 - 0.024 14.6 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Peptidase_S15 PF02129.18 ETS82700.1 - 3.5e-43 148.1 5.7 1.1e-39 136.6 1.1 2.6 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ETS82700.1 - 1.8e-23 83.7 0.6 5e-23 82.2 0.6 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 ETS82700.1 - 0.17 11.1 0.0 0.45 9.7 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Zn_clus PF00172.18 ETS82701.1 - 3e-08 33.7 12.4 5.4e-08 32.8 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS82701.1 - 9.3e-06 24.9 0.0 1.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain rRNA_methylase PF06962.12 ETS82702.1 - 0.09 12.7 0.1 0.56 10.2 0.1 2.0 2 0 0 2 2 2 0 Putative rRNA methylase Popeye PF04831.13 ETS82702.1 - 9.2 6.4 8.9 1.7 8.8 1.4 2.2 2 0 0 2 2 2 0 Popeye protein conserved region Lipase_GDSL PF00657.22 ETS82703.1 - 1.1e-12 48.4 0.0 2e-12 47.5 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ETS82703.1 - 6.9e-06 26.6 0.5 1e-05 26.0 0.5 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Peripla_BP_3 PF13377.6 ETS82703.1 - 0.00032 21.1 0.0 0.00051 20.4 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein-like domain EphA2_TM PF14575.6 ETS82705.1 - 0.018 15.9 0.0 0.044 14.7 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 ETS82705.1 - 0.02 14.6 1.2 0.039 13.7 1.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DAG1 PF05454.11 ETS82705.1 - 0.16 11.3 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Apt1 PF10351.9 ETS82705.1 - 0.23 10.3 6.4 0.3 9.9 6.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 ETS82705.1 - 0.27 11.1 8.1 0.019 14.9 3.7 1.4 2 0 0 2 2 2 0 SPX domain INO80_Ies4 PF08193.11 ETS82705.1 - 1.6 8.7 12.4 3 7.8 12.4 1.4 1 0 0 1 1 1 0 INO80 complex subunit Ies4 MGC-24 PF05283.11 ETS82705.1 - 9.3 6.7 24.8 0.17 12.3 14.8 2.3 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Thymidylat_synt PF00303.19 ETS82706.1 - 3.8e-110 367.2 0.0 4.4e-110 367.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase HTH_ABP1_N PF18107.1 ETS82707.1 - 1.6e-25 88.5 2.0 4e-25 87.3 2.0 1.7 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 ETS82707.1 - 3.4e-17 62.2 0.8 5.9e-16 58.2 0.1 2.7 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain DUF434 PF04256.12 ETS82707.1 - 0.19 11.4 0.7 0.47 10.2 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF434) SH3_1 PF00018.28 ETS82708.1 - 3e-27 94.0 0.0 3.6e-13 48.9 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 ETS82708.1 - 5.2e-19 67.9 0.1 1.5e-09 37.6 0.1 2.8 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 ETS82708.1 - 9.7e-14 51.3 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 ETS82708.1 - 3.2e-12 46.0 0.0 5.8e-08 32.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 ETS82708.1 - 7.9e-07 28.9 0.2 1.4e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 PB1 domain Glyco_hydro_17 PF00332.18 ETS82709.1 - 2.6e-08 33.8 0.3 3.7e-08 33.3 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Hamartin PF04388.12 ETS82710.1 - 6.2e-12 45.0 55.7 1.8e-09 36.9 55.6 4.3 1 1 0 1 1 1 1 Hamartin protein Semialdhyde_dhC PF02774.18 ETS82710.1 - 0.03 14.4 0.5 0.074 13.1 0.5 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain DJ-1_PfpI PF01965.24 ETS82711.1 - 4.9e-12 46.0 0.1 8.4e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ETS82711.1 - 0.0036 17.0 0.0 0.0052 16.5 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like Ribosomal_L23 PF00276.20 ETS82712.1 - 5.4e-09 36.3 0.0 9.6e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 Arc_PepC_II PF06847.11 ETS82712.1 - 0.064 13.8 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Myosin_tail_1 PF01576.19 ETS82713.1 - 4.1e-08 31.6 90.9 5.8e-08 31.1 90.9 1.1 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 ETS82713.1 - 4e-05 23.4 88.9 0.01 15.5 15.2 4.9 2 2 2 4 4 4 2 Intermediate filament protein DUF4200 PF13863.6 ETS82713.1 - 0.00084 19.7 21.5 0.00084 19.7 21.5 6.1 1 1 5 6 6 5 1 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.9 ETS82713.1 - 0.00092 19.2 97.9 0.0012 18.9 20.6 6.1 1 1 4 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 ETS82713.1 - 0.0011 18.6 25.3 0.0011 18.6 25.3 6.2 2 2 3 6 6 6 1 Ciliary protein causing Leber congenital amaurosis disease Tropomyosin_1 PF12718.7 ETS82713.1 - 0.0084 16.3 25.5 0.0084 16.3 25.5 6.3 2 1 5 7 7 7 3 Tropomyosin like TMF_DNA_bd PF12329.8 ETS82713.1 - 0.018 15.0 10.5 0.018 15.0 10.5 9.5 2 2 9 12 12 11 0 TATA element modulatory factor 1 DNA binding GAS PF13851.6 ETS82713.1 - 0.02 14.2 94.0 0.13 11.6 21.3 5.0 1 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding Pox_A_type_inc PF04508.12 ETS82713.1 - 0.058 13.3 5.1 1.1 9.2 0.5 4.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat LigT_PEase PF02834.16 ETS82713.1 - 0.19 11.9 1.0 1.7 8.9 0.0 3.2 3 1 0 3 3 2 0 LigT like Phosphoesterase HALZ PF02183.18 ETS82713.1 - 0.32 11.3 0.1 0.32 11.3 0.1 6.1 7 1 0 7 7 6 0 Homeobox associated leucine zipper Tropomyosin PF00261.20 ETS82713.1 - 0.43 9.9 100.8 6.2 6.1 27.5 6.2 1 1 5 6 6 6 0 Tropomyosin ATG16 PF08614.11 ETS82713.1 - 0.6 10.3 98.1 1.1 9.4 16.1 5.4 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) HOOK PF05622.12 ETS82713.1 - 0.71 7.9 90.3 29 2.6 89.6 3.0 1 1 0 1 1 1 0 HOOK protein Fez1 PF06818.15 ETS82713.1 - 1.8 9.0 87.1 6.2 7.2 27.8 4.8 1 1 3 4 4 4 0 Fez1 Spc7 PF08317.11 ETS82713.1 - 3.5 6.4 90.5 0.04 12.8 31.2 4.6 1 1 3 4 4 4 0 Spc7 kinetochore protein AAA_13 PF13166.6 ETS82713.1 - 4.9 5.7 74.4 0.29 9.7 13.2 3.3 1 1 1 3 3 3 0 AAA domain adh_short PF00106.25 ETS82714.1 - 1.3e-45 155.3 2.2 1.7e-45 154.9 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS82714.1 - 1.2e-35 123.2 1.0 1.4e-35 122.9 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS82714.1 - 3.5e-11 43.3 1.4 5e-11 42.8 1.4 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 ETS82714.1 - 1.7e-06 27.8 2.0 4.4e-06 26.4 1.9 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS82714.1 - 7.2e-06 26.0 1.0 7.2e-06 26.0 1.0 1.7 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 ETS82714.1 - 0.00017 21.2 0.7 0.00059 19.4 0.7 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 ETS82714.1 - 0.00041 20.3 0.9 0.00073 19.5 0.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 ETS82714.1 - 0.0055 16.0 0.1 0.0071 15.6 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DFP PF04127.15 ETS82714.1 - 0.0083 16.0 0.9 0.013 15.3 0.9 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein DUF1776 PF08643.10 ETS82714.1 - 0.018 14.4 0.0 0.093 12.1 0.0 1.8 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) TrkA_N PF02254.18 ETS82714.1 - 0.028 14.7 0.3 0.07 13.4 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 ETS82714.1 - 0.04 13.3 0.1 0.059 12.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 ETS82714.1 - 0.048 12.8 0.2 0.071 12.2 0.2 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain PALP PF00291.25 ETS82714.1 - 0.1 12.0 1.4 0.15 11.5 1.4 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DNA_pol_lambd_f PF10391.9 ETS82714.1 - 0.14 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda MT-A70 PF05063.14 ETS82715.1 - 5.9e-31 107.7 0.2 1e-30 106.9 0.2 1.4 1 0 0 1 1 1 1 MT-A70 Cons_hypoth95 PF03602.15 ETS82715.1 - 0.19 11.4 0.0 1 9.0 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein 95 RSN1_7TM PF02714.15 ETS82716.1 - 4.8e-81 272.1 21.5 4.8e-81 272.1 21.5 2.5 4 0 0 4 4 4 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ETS82716.1 - 6.5e-43 146.2 0.4 6.5e-43 146.2 0.4 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ETS82716.1 - 2.4e-28 99.6 4.8 1e-16 61.7 0.2 2.5 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 ETS82716.1 - 2e-15 56.7 0.0 5.3e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter DUF3981 PF13139.6 ETS82716.1 - 0.76 10.2 3.5 0.38 11.1 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3981) DUF4746 PF15928.5 ETS82716.1 - 1.9 7.9 8.2 4.2 6.7 5.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) CopD PF05425.13 ETS82716.1 - 3.4 8.1 10.1 9.9 6.6 1.3 3.6 3 0 0 3 3 3 0 Copper resistance protein D AIM3 PF17096.5 ETS82716.1 - 5.1 8.1 7.9 0.96 10.4 0.2 2.8 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 FAD_binding_3 PF01494.19 ETS82717.1 - 6.6e-19 68.4 1.9 5.1e-15 55.6 0.2 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS82717.1 - 7e-05 23.0 0.2 0.00018 21.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 ETS82717.1 - 0.00018 20.7 0.0 0.0042 16.2 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_9 PF13454.6 ETS82717.1 - 0.0012 18.9 0.1 0.018 15.0 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ETS82717.1 - 0.0014 18.0 0.0 0.0028 17.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS82717.1 - 0.0028 17.3 1.1 0.0095 15.6 1.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ETS82717.1 - 0.051 12.4 0.1 0.087 11.7 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 ETS82717.1 - 0.054 14.1 0.1 0.13 12.9 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ETS82717.1 - 0.055 12.8 0.1 0.093 12.0 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 ETS82717.1 - 0.076 12.1 1.4 0.15 11.1 1.0 1.6 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 ETS82717.1 - 0.17 11.1 0.1 0.29 10.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FMN_dh PF01070.18 ETS82718.1 - 8.2e-86 288.2 0.0 1.6e-45 155.7 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 ETS82718.1 - 0.0017 17.5 0.3 0.035 13.1 0.2 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ETS82718.1 - 0.034 13.3 0.0 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase MFS_1 PF07690.16 ETS82719.1 - 1.4e-33 116.3 36.3 2.3e-33 115.6 36.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS82719.1 - 2.1e-07 30.2 19.6 1e-05 24.6 19.6 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 ETS82719.1 - 3.1e-05 22.6 4.2 5.4e-05 21.8 4.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 ETS82719.1 - 0.001 18.4 7.8 0.001 18.4 7.8 2.0 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB EMP70 PF02990.16 ETS82720.1 - 4.5e-209 695.4 0.4 5.4e-209 695.2 0.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF5305 PF17231.2 ETS82720.1 - 0.076 12.4 0.4 0.35 10.2 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Mito_carr PF00153.27 ETS82721.1 - 1.3e-59 198.1 7.8 4.3e-21 74.6 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ETS82721.1 - 0.0053 16.0 0.1 0.63 9.1 0.1 2.6 2 1 0 2 2 2 2 Gammaproteobacterial serine protease Ac76 PF05814.11 ETS82723.1 - 0.1 12.6 1.2 0.14 12.2 0.7 1.5 1 1 0 1 1 1 0 Orf76 (Ac76) MerC PF03203.14 ETS82723.1 - 0.4 11.2 5.4 1.8 9.0 3.6 2.2 1 1 1 2 2 2 0 MerC mercury resistance protein Glyco_hydro_39 PF01229.17 ETS82724.1 - 3.2e-05 22.7 0.2 4.8e-05 22.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 2OG-FeII_Oxy_2 PF13532.6 ETS82725.1 - 9.2e-34 117.3 0.0 1.2e-33 116.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 ETS82725.1 - 5e-11 42.5 4.1 9.1e-11 41.7 4.1 1.4 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.16 ETS82725.1 - 0.022 14.4 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 CUE domain WD40 PF00400.32 ETS82726.1 - 1.7e-14 53.9 12.4 0.013 16.3 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS82726.1 - 0.00013 22.2 0.0 0.29 11.5 0.0 4.0 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 ETS82726.1 - 0.13 12.3 0.0 0.68 10.0 0.0 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region SH3_18 PF18354.1 ETS82726.1 - 0.14 12.3 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 CarS bacterial SH3 domain DHC_N1 PF08385.12 ETS82727.1 - 0.0097 14.6 0.1 0.014 14.1 0.1 1.2 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 CNTF PF01110.17 ETS82727.1 - 0.032 13.6 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Ciliary neurotrophic factor SMN PF06003.12 ETS82729.1 - 0.14 11.4 3.7 0.26 10.5 3.7 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Mito_fiss_reg PF05308.11 ETS82729.1 - 1.9 8.5 10.5 0.14 12.2 5.6 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator CAP_N PF01213.19 ETS82729.1 - 6.9 6.1 7.0 11 5.4 7.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Fungal_trans PF04082.18 ETS82730.1 - 1.2e-26 93.4 0.0 1.7e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS82730.1 - 1.4e-07 31.5 10.2 2.2e-07 30.9 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ETS82731.1 - 3e-38 131.7 26.6 2.5e-30 105.6 2.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS82731.1 - 9.3e-12 44.5 1.2 9.3e-12 44.5 1.2 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter Transp_cyt_pur PF02133.15 ETS82732.1 - 1.4e-26 93.3 36.7 4.1e-26 91.7 35.8 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2208 PF09973.9 ETS82732.1 - 3.3 7.3 7.6 16 5.1 0.4 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) RibD_C PF01872.17 ETS82733.1 - 4.6e-36 124.5 0.0 5.5e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain HgmA PF04209.13 ETS82734.1 - 2.2e-147 491.2 0.1 2.7e-147 490.9 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase CYSTM PF12734.7 ETS82735.1 - 0.0039 17.5 71.5 1.8e+04 -12.4 71.5 5.0 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance FAD_binding_3 PF01494.19 ETS82736.1 - 3.1e-24 85.9 0.1 6.1e-24 84.9 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ETS82736.1 - 9.2e-08 32.2 0.1 2.1e-07 31.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS82736.1 - 1.5e-06 28.1 1.2 0.0012 18.4 0.8 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS82736.1 - 4.7e-06 26.1 0.6 0.00046 19.5 0.2 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS82736.1 - 0.0001 21.5 0.8 0.00019 20.7 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 ETS82736.1 - 0.0022 17.1 1.2 0.0034 16.5 1.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 ETS82736.1 - 0.0053 16.0 0.1 0.0094 15.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family SE PF08491.10 ETS82736.1 - 0.0074 15.4 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase ThiF PF00899.21 ETS82736.1 - 0.022 14.1 0.0 0.053 12.9 0.0 1.6 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.6 ETS82736.1 - 0.044 13.0 0.5 0.12 11.6 0.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ETS82736.1 - 0.074 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 ETS82736.1 - 0.083 13.5 0.1 0.17 12.4 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ETS82736.1 - 0.17 10.7 0.1 0.26 10.1 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 ETS82736.1 - 0.21 10.2 0.3 0.33 9.6 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein PfkB PF00294.24 ETS82737.1 - 1.4e-54 185.5 1.3 1.8e-54 185.1 1.3 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase UQ_con PF00179.26 ETS82738.1 - 4.8e-10 39.2 0.0 7.4e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Cas_Csa5 PF09702.10 ETS82738.1 - 0.17 12.2 0.0 28 5.0 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) MFS_1 PF07690.16 ETS82739.1 - 1.3e-20 73.7 69.0 1.2e-16 60.6 37.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cupin_2 PF07883.11 ETS82740.1 - 4e-10 39.2 0.6 6.8e-10 38.5 0.6 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 ETS82740.1 - 0.00034 20.2 0.3 0.0007 19.2 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 ETS82740.1 - 0.00088 19.2 0.6 0.0012 18.8 0.6 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_7 PF12973.7 ETS82740.1 - 0.0025 17.7 0.1 0.0045 16.9 0.1 1.4 1 0 0 1 1 1 1 ChrR Cupin-like domain Cupin_6 PF12852.7 ETS82740.1 - 0.012 15.4 0.1 0.014 15.2 0.1 1.1 1 0 0 1 1 1 0 Cupin DUF3425 PF11905.8 ETS82741.1 - 4.8e-16 58.9 0.0 1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_Maf PF03131.17 ETS82741.1 - 0.024 15.2 6.3 0.041 14.4 6.3 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF4239 PF14023.6 ETS82741.1 - 0.064 13.0 0.1 0.09 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) UreD PF01774.17 ETS82741.1 - 0.1 12.5 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 UreD urease accessory protein ADH_N PF08240.12 ETS82742.1 - 9.6e-22 76.9 3.2 1.5e-21 76.3 3.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS82742.1 - 1.9e-19 69.9 0.0 3.2e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS82742.1 - 2.7e-07 31.7 0.0 5.3e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ETS82742.1 - 0.0091 15.4 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ETS82742.1 - 0.01 15.1 0.7 0.016 14.5 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 ETS82742.1 - 0.013 15.0 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NAD_binding_2 PF03446.15 ETS82742.1 - 0.068 13.3 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N PF08240.12 ETS82743.1 - 3.5e-15 55.8 0.2 8.8e-15 54.5 0.2 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS82743.1 - 5.3e-06 26.4 0.0 1.8e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS82743.1 - 0.00037 20.1 0.1 0.00084 18.9 0.0 1.6 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 ETS82743.1 - 0.0038 17.1 1.1 0.017 15.0 0.2 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Ccdc124 PF06244.12 ETS82744.1 - 4.5e-30 104.8 18.6 6.9e-29 101.0 18.6 2.1 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 TMEM214 PF10151.9 ETS82744.1 - 0.38 9.2 13.4 0.49 8.8 13.4 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator SNF2_N PF00176.23 ETS82745.1 - 3.2e-60 203.7 0.2 4.5e-60 203.2 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS82745.1 - 2.7e-14 53.5 0.0 8.7e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS82745.1 - 5.1e-05 23.3 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ETS82745.1 - 0.00042 20.1 0.0 0.00097 18.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 ETS82745.1 - 0.002 17.8 0.0 2.8 7.5 0.0 3.0 3 0 0 3 3 3 2 SWI2/SNF2 ATPase NACHT PF05729.12 ETS82746.1 - 6.5e-06 26.2 0.5 8.2e-05 22.6 0.5 2.6 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 ETS82746.1 - 0.003 16.8 0.0 1.9 7.6 0.1 2.6 2 0 0 2 2 2 2 NB-ARC domain Zeta_toxin PF06414.12 ETS82746.1 - 0.079 12.2 0.0 0.54 9.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin GFA PF04828.14 ETS82747.1 - 2.9e-09 37.2 7.7 5.3e-06 26.7 0.2 2.9 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 ETS82747.1 - 0.16 11.9 0.1 0.16 11.9 0.1 3.7 5 0 0 5 5 5 0 Nudix N-terminal Myb_Cef PF11831.8 ETS82748.1 - 5.6e-42 144.0 7.9 5.6e-42 144.0 7.9 3.6 3 1 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 ETS82748.1 - 1e-23 83.3 6.2 1.9e-11 44.0 1.3 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ETS82748.1 - 5.1e-21 74.7 7.7 1.2e-14 54.3 3.2 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.8 ETS82748.1 - 0.014 15.5 0.1 0.014 15.5 0.1 2.9 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF5344 PF17279.2 ETS82748.1 - 0.072 13.7 1.2 3.4 8.3 0.1 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5344) RuvX PF03652.15 ETS82748.1 - 0.11 12.9 1.3 0.22 11.9 0.1 2.2 2 0 0 2 2 2 0 Holliday junction resolvase XhlA PF10779.9 ETS82748.1 - 6.3 7.1 9.9 9.7 6.5 0.2 4.1 4 0 0 4 4 4 0 Haemolysin XhlA MFS_1 PF07690.16 ETS82749.1 - 2.3e-42 145.2 44.1 2.3e-42 145.2 44.1 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS82749.1 - 9.1e-09 34.7 14.5 9.1e-09 34.7 14.5 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 ETS82749.1 - 0.0083 14.5 4.3 0.013 13.9 3.2 1.9 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Antimicrobial24 PF16049.5 ETS82749.1 - 1.9 8.6 7.9 0.36 10.9 2.0 2.5 2 0 0 2 2 2 0 Frog antimicrobial peptide Hexokinase_1 PF00349.21 ETS82750.1 - 3.5e-51 173.9 0.0 4.9e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 ETS82750.1 - 9.5e-45 152.9 0.0 1.2e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Hexokinase GILT PF03227.16 ETS82751.1 - 7e-21 74.5 0.1 1e-20 73.9 0.1 1.2 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DcpS PF05652.12 ETS82752.1 - 4.6e-32 111.0 0.0 8.3e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 ETS82752.1 - 4.9e-31 107.6 0.8 8.5e-31 106.8 0.8 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Abhydrolase_6 PF12697.7 ETS82753.1 - 7.4e-16 59.4 0.1 8.9e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 ETS82753.1 - 2.5e-05 23.3 0.0 3.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 ETS82753.1 - 7.9e-05 22.0 0.1 0.0007 18.9 0.1 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS82753.1 - 0.00012 21.9 0.2 0.14 11.8 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Chlorophyllase PF07224.11 ETS82753.1 - 0.028 13.4 0.1 0.054 12.5 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase DUF3089 PF11288.8 ETS82753.1 - 0.029 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Glyco_hydro_43 PF04616.14 ETS82754.1 - 1.6e-105 352.6 1.4 3.5e-105 351.5 0.7 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ETS82754.1 - 1.7e-46 158.5 0.0 2.5e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Ank_2 PF12796.7 ETS82755.1 - 1.4e-82 272.3 0.0 3.7e-13 49.9 0.0 7.7 2 1 8 10 10 10 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS82755.1 - 3.5e-49 159.1 0.9 8.1e-05 22.7 0.0 13.0 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.6 ETS82755.1 - 1.6e-46 155.7 8.8 1.7e-11 44.1 0.1 8.9 2 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 ETS82755.1 - 9.4e-43 142.8 6.9 0.0046 17.4 0.0 12.9 12 1 0 12 12 12 9 Ankyrin repeat Ank_4 PF13637.6 ETS82755.1 - 1.4e-33 114.8 0.7 3.8e-06 27.3 0.0 8.2 5 2 4 9 9 8 8 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 ETS82755.1 - 8.7e-13 48.1 2.9 5.5e-12 45.4 2.9 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 ETS82755.1 - 1.5e-06 28.3 0.0 3.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ETS82755.1 - 0.00038 20.7 0.1 0.001 19.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS82755.1 - 0.0011 19.3 0.0 0.0052 17.2 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ETS82755.1 - 0.014 15.8 0.0 0.047 14.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) G6B PF15096.6 ETS82755.1 - 0.088 12.6 0.0 47 3.7 0.0 4.1 5 0 0 5 5 5 0 G6B family DUF2075 PF09848.9 ETS82755.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MitMem_reg PF13012.6 ETS82758.1 - 7.3e-13 48.9 0.3 1.7e-12 47.7 0.3 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 ETS82758.1 - 2.6e-08 33.9 0.0 7.2e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ADH_N PF08240.12 ETS82759.1 - 3.8e-27 94.3 0.5 9.9e-27 93.0 0.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS82759.1 - 4.6e-16 59.0 0.0 1.5e-11 44.4 0.0 2.2 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS82759.1 - 8.3e-09 35.2 0.6 0.00011 21.8 0.2 2.8 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 ETS82759.1 - 0.0026 17.1 0.2 0.0043 16.4 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 ETS82759.1 - 0.0032 18.5 0.0 0.0068 17.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.21 ETS82759.1 - 0.014 14.8 0.1 0.022 14.1 0.1 1.2 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.14 ETS82759.1 - 0.026 14.1 0.1 0.06 12.9 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Vps5 PF09325.10 ETS82760.1 - 1.5e-11 44.3 0.2 2.7e-11 43.5 0.2 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 ETS82760.1 - 1.9e-08 34.3 0.0 3.4e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 PX domain Presenilin PF01080.17 ETS82760.1 - 8.3 5.1 6.3 14 4.3 6.3 1.4 1 0 0 1 1 1 0 Presenilin GTP_EFTU PF00009.27 ETS82761.1 - 1.4e-52 178.1 0.0 2.3e-52 177.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 ETS82761.1 - 1e-19 70.4 0.0 2.3e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 ETS82761.1 - 2.5e-14 53.0 0.0 6.1e-07 29.4 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus RF3_C PF16658.5 ETS82761.1 - 9.5e-07 28.7 0.0 2.3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 ETS82761.1 - 1.9e-06 28.2 0.0 6.5e-06 26.4 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 UBM PF14377.6 ETS82762.1 - 0.069 12.6 0.3 0.19 11.2 0.3 1.8 1 0 0 1 1 1 0 Ubiquitin binding region MAGE_N PF12440.8 ETS82762.1 - 4.6 8.0 8.9 4.6e+02 1.6 8.9 2.5 1 1 0 1 1 1 0 Melanoma associated antigen family N terminal DivIVA PF05103.13 ETS82763.1 - 0.88 9.7 15.9 0.19 11.8 11.7 2.1 2 0 0 2 2 2 0 DivIVA protein Sugar_tr PF00083.24 ETS82764.1 - 1.1e-52 179.5 15.6 1.9e-52 178.7 15.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS82764.1 - 8.9e-20 70.9 26.2 1.5e-19 70.1 26.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_1 PF00561.20 ETS82765.1 - 6.7e-48 163.6 0.0 2e-47 162.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS82765.1 - 1.2e-05 26.1 1.0 4.1e-05 24.3 1.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 ETS82765.1 - 0.026 13.4 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase Abhydrolase_4 PF08386.10 ETS82765.1 - 0.14 12.2 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 TAP-like protein THOC2_N PF16134.5 ETS82766.1 - 7.3e-207 688.9 0.0 1.1e-206 688.4 0.0 1.2 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 ETS82766.1 - 1.2e-86 290.7 0.1 1.8e-86 290.0 0.1 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 ETS82766.1 - 2.4e-26 91.6 0.0 7.8e-26 89.9 0.0 2.0 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Solute_trans_a PF03619.16 ETS82767.1 - 1.5e-87 293.5 20.9 1.9e-87 293.1 20.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PrgI PF12666.7 ETS82767.1 - 0.022 15.5 0.8 0.022 15.5 0.8 2.6 2 1 0 2 2 2 0 PrgI family protein PBP1_TM PF14812.6 ETS82767.1 - 0.32 11.4 4.2 0.82 10.1 4.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FXR_C1 PF16096.5 ETS82767.1 - 1.5 9.1 7.4 0.28 11.4 2.7 2.1 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 WSC PF01822.19 ETS82768.1 - 8.8e-12 45.1 11.4 8.8e-12 45.1 11.4 1.9 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.10 ETS82768.1 - 1.2e-07 31.0 0.3 2.5e-07 30.0 0.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 ETS82768.1 - 0.00061 19.9 3.9 0.00061 19.9 3.9 1.6 2 0 0 2 2 2 1 Podoplanin MAP17 PF15807.5 ETS82768.1 - 0.1 12.9 0.0 15 5.9 0.0 2.6 3 0 0 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 CENP-K PF11802.8 ETS82770.1 - 0.0028 17.3 2.8 0.005 16.5 2.8 1.4 1 0 0 1 1 1 1 Centromere-associated protein K DUF4407 PF14362.6 ETS82770.1 - 0.63 9.3 10.7 0.29 10.4 7.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TSC22 PF01166.18 ETS82770.1 - 3.5 8.0 6.7 6.7 7.1 2.5 2.8 2 1 0 2 2 2 0 TSC-22/dip/bun family RSN1_7TM PF02714.15 ETS82771.1 - 1.9e-87 293.1 25.7 1.9e-87 293.1 25.7 3.0 3 0 0 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ETS82771.1 - 1.3e-47 161.4 2.4 1.3e-47 161.4 2.4 3.3 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ETS82771.1 - 7.7e-36 124.0 0.0 1.2e-35 123.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 ETS82771.1 - 1.1e-32 112.0 0.2 5e-32 109.9 0.1 2.0 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter kleA_kleC PF17383.2 ETS82771.1 - 0.039 14.3 0.1 0.15 12.4 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A E1_DerP2_DerF2 PF02221.15 ETS82772.1 - 2.6e-26 92.7 0.2 3.1e-26 92.4 0.2 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 ETS82772.1 - 0.0034 17.8 0.0 0.0072 16.7 0.0 1.6 1 1 0 1 1 1 1 ML-like domain ATP-synt_F PF01990.17 ETS82773.1 - 1e-33 115.5 0.1 1.2e-33 115.3 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.6 ETS82773.1 - 0.083 12.1 0.0 0.083 12.1 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DUF2418 PF10332.9 ETS82774.1 - 6.5e-32 109.9 1.6 1.5e-31 108.8 1.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Aconitase PF00330.20 ETS82776.1 - 8.8e-158 526.1 0.0 1.3e-157 525.5 0.0 1.3 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ETS82776.1 - 7.2e-39 133.1 0.0 1.3e-38 132.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 ETS82776.1 - 0.008 14.9 0.0 0.018 13.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF521) Epimerase PF01370.21 ETS82777.1 - 4.6e-10 39.4 0.1 0.00014 21.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ETS82777.1 - 6.3e-06 25.5 0.2 4.2e-05 22.9 0.1 2.1 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 ETS82777.1 - 5.5e-05 23.1 0.4 0.00018 21.4 0.3 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 ETS82777.1 - 0.00073 19.2 0.3 0.0011 18.5 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 ETS82777.1 - 0.012 14.6 0.0 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family TatD_DNase PF01026.21 ETS82777.1 - 0.2 11.0 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 TatD related DNase MFS_1 PF07690.16 ETS82778.1 - 5.6e-09 35.4 16.2 5.6e-09 35.4 16.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 ETS82779.1 - 3.9e-35 121.4 27.8 6.4e-35 120.7 27.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS82779.1 - 2.9e-15 56.1 4.4 4.5e-15 55.5 4.4 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 ETS82779.1 - 3.9e-15 55.3 12.3 4.8e-15 55.0 12.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) EthD PF07110.11 ETS82780.1 - 2.8e-10 41.2 0.1 3.8e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 EthD domain NmrA PF05368.13 ETS82781.1 - 2.6e-15 56.6 0.0 3.5e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS82781.1 - 1.6e-13 50.9 0.3 1.8e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding DapB_N PF01113.20 ETS82781.1 - 5.1e-05 23.4 0.2 0.0047 17.1 0.1 2.2 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 ETS82781.1 - 0.00024 21.2 0.0 0.00043 20.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 ETS82781.1 - 0.00027 20.5 0.1 0.00062 19.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS82781.1 - 0.00035 19.7 0.0 0.00051 19.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 ETS82781.1 - 0.00041 20.9 0.4 0.0016 19.0 0.4 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 ETS82781.1 - 0.00054 20.2 0.1 0.022 15.0 0.1 2.3 2 0 0 2 2 2 1 TrkA-N domain Semialdhyde_dh PF01118.24 ETS82781.1 - 0.0064 16.9 0.5 0.024 15.1 0.2 2.0 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ETS82781.1 - 0.0098 16.3 0.1 0.02 15.3 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Polysacc_synt_2 PF02719.15 ETS82781.1 - 0.02 14.0 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 ETS82781.1 - 0.03 14.2 0.1 0.058 13.3 0.1 1.5 1 0 0 1 1 1 0 KR domain DnaJ PF00226.31 ETS82782.1 - 4.2e-22 78.0 0.7 1.1e-21 76.7 0.7 1.8 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.18 ETS82783.1 - 6.4e-11 41.8 0.5 1.7e-10 40.4 0.5 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Nro1 PF12753.7 ETS82783.1 - 0.07 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Ring_hydroxyl_A PF00848.19 ETS82784.1 - 2.8e-21 76.5 3.6 3.9e-11 43.3 0.9 3.1 1 1 2 3 3 3 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 ETS82784.1 - 6.3e-14 51.7 0.0 1.6e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain INCENP_ARK-bind PF03941.15 ETS82785.1 - 4e-18 65.1 1.1 4e-18 65.1 1.1 3.5 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region NOT2_3_5 PF04153.18 ETS82786.1 - 1.4e-28 99.6 0.6 2.7e-28 98.7 0.6 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family cobW PF02492.19 ETS82787.1 - 7.2e-49 165.8 0.3 9.6e-49 165.3 0.3 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 ETS82787.1 - 9.9e-07 28.8 0.2 0.046 13.6 0.0 2.5 2 1 0 2 2 2 2 RsgA GTPase CobW_C PF07683.14 ETS82787.1 - 0.00051 19.9 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MeaB PF03308.16 ETS82787.1 - 0.0028 16.7 0.5 2.3 7.1 0.0 2.9 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 ETS82787.1 - 0.0029 17.2 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ETS82787.1 - 0.0084 16.2 0.0 0.022 14.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 ETS82787.1 - 0.011 16.2 0.3 0.021 15.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ETS82787.1 - 0.013 15.3 0.5 0.46 10.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ETS82787.1 - 0.015 15.7 0.0 0.043 14.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 ETS82787.1 - 0.017 14.9 0.7 0.11 12.3 0.7 2.0 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 ETS82787.1 - 0.027 14.8 0.2 0.35 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ETS82787.1 - 0.038 13.7 0.2 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain TsaE PF02367.17 ETS82787.1 - 0.04 13.9 0.3 0.097 12.7 0.1 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 ETS82787.1 - 0.054 12.8 0.7 9.3 5.4 0.1 2.4 2 1 0 2 2 2 0 Septin T2SSE PF00437.20 ETS82787.1 - 0.055 12.5 1.2 0.062 12.3 0.1 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 ETS82787.1 - 0.19 11.0 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Mob1_phocein PF03637.17 ETS82788.1 - 9.3e-23 81.1 0.6 1.7e-22 80.2 0.4 1.5 2 0 0 2 2 2 1 Mob1/phocein family Fungal_trans_2 PF11951.8 ETS82789.1 - 2.8e-13 49.5 0.2 8.8e-13 47.8 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS82789.1 - 6.1e-07 29.5 10.7 9.8e-07 28.8 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain eIF3m_C_helix PF18005.1 ETS82789.1 - 0.23 11.2 0.3 0.53 10.0 0.3 1.6 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix MOSC PF03473.17 ETS82790.1 - 9.2e-24 83.9 0.0 1.6e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 ETS82790.1 - 1.7e-11 44.1 0.0 3.5e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain SMC_N PF02463.19 ETS82791.1 - 1.9e-61 207.3 35.4 4.1e-59 199.7 35.4 4.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ETS82791.1 - 5.7e-23 81.5 1.2 5.5e-22 78.3 0.1 3.2 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 ETS82791.1 - 1.8e-10 41.1 3.9 0.00019 21.4 0.2 3.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ETS82791.1 - 0.00012 21.8 0.1 0.00028 20.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ETS82791.1 - 0.00044 20.8 38.4 0.00044 20.8 38.4 6.7 2 2 2 4 4 4 1 AAA domain DUF4250 PF14056.6 ETS82791.1 - 0.0048 16.8 3.5 9.2 6.3 0.1 4.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4250) HIP1_clath_bdg PF16515.5 ETS82791.1 - 0.007 17.0 8.2 0.007 17.0 8.2 8.7 3 2 6 9 9 9 1 Clathrin-binding domain of Huntingtin-interacting protein 1 CUE PF02845.16 ETS82792.1 - 4.7e-11 42.2 0.0 7.1e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 ETS82792.1 - 0.54 10.0 7.9 1.4 8.7 7.9 1.6 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) Cue1_U7BR PF18499.1 ETS82792.1 - 0.56 10.3 4.1 1.2 9.3 4.1 1.6 1 1 0 1 1 1 0 Ubc7p-binding region of Cue1 VIR_N PF15912.5 ETS82792.1 - 0.71 9.4 3.9 0.97 9.0 3.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Pterin_4a PF01329.19 ETS82793.1 - 0.063 13.5 0.0 6.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase DEAD PF00270.29 ETS82794.1 - 5.8e-42 143.4 0.0 8.4e-42 142.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS82794.1 - 3.3e-21 75.7 0.0 2.3e-19 69.8 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS82794.1 - 0.00065 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ETS82794.1 - 0.08 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase VASt PF16016.5 ETS82796.1 - 1.1e-38 133.1 0.0 2.1e-38 132.1 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 ETS82796.1 - 2.2e-23 82.3 0.0 3.5e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 GRAM domain TolA_bind_tri PF16331.5 ETS82797.1 - 0.0055 16.8 2.0 0.14 12.2 0.8 2.9 2 0 0 2 2 2 1 TolA binding protein trimerisation bZIP_1 PF00170.21 ETS82797.1 - 0.034 14.3 6.2 2.3 8.4 1.5 2.9 2 0 0 2 2 2 0 bZIP transcription factor APC_N_CC PF16689.5 ETS82797.1 - 0.039 14.0 3.1 1 9.4 0.1 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain KASH_CCD PF14662.6 ETS82797.1 - 0.059 13.2 6.9 0.35 10.7 0.2 3.0 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH CENP-Q PF13094.6 ETS82797.1 - 0.13 12.4 8.1 0.45 10.7 0.7 3.4 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Cep57_MT_bd PF06657.13 ETS82797.1 - 0.17 12.4 7.1 5.4 7.6 0.4 3.3 3 0 0 3 3 2 0 Centrosome microtubule-binding domain of Cep57 Retrotrans_gag PF03732.17 ETS82797.1 - 0.36 11.1 1.8 0.56 10.5 0.4 2.1 2 0 0 2 2 1 0 Retrotransposon gag protein Fib_alpha PF08702.10 ETS82797.1 - 0.49 10.6 2.1 0.47 10.6 0.4 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family NRBF2_MIT PF17169.4 ETS82797.1 - 0.49 10.6 4.1 1.8 8.8 4.1 2.0 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 Ax_dynein_light PF10211.9 ETS82797.1 - 1.2 9.1 4.4 12 5.8 2.2 2.4 2 0 0 2 2 2 0 Axonemal dynein light chain SOGA PF11365.8 ETS82797.1 - 1.2 10.3 7.7 0.24 12.5 0.8 3.0 3 0 0 3 3 3 0 Protein SOGA SlyX PF04102.12 ETS82797.1 - 1.2 9.8 7.8 1.9 9.2 0.8 3.3 3 0 0 3 3 3 0 SlyX GIT_CC PF16559.5 ETS82797.1 - 1.3 8.9 6.0 1.2 9.0 2.0 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DASH_Dam1 PF08653.10 ETS82797.1 - 1.5 8.7 4.5 15 5.5 0.4 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 DivIC PF04977.15 ETS82797.1 - 2.1 8.2 6.0 9.6 6.1 2.8 2.6 2 0 0 2 2 2 0 Septum formation initiator DUF4515 PF14988.6 ETS82797.1 - 2.6 7.9 7.7 6.4 6.6 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4515) Rootletin PF15035.6 ETS82797.1 - 4.2 7.4 15.0 0.64 10.0 8.2 2.7 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 ETS82797.1 - 6.6 7.4 7.1 4.8 7.9 0.3 2.9 3 0 0 3 3 3 0 Initiation control protein YabA Cnn_1N PF07989.11 ETS82797.1 - 7.1 6.9 8.7 30 4.9 0.3 2.9 2 1 1 3 3 2 0 Centrosomin N-terminal motif 1 DUF4201 PF13870.6 ETS82797.1 - 7.4 6.3 12.1 3.8 7.2 2.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) GAS PF13851.6 ETS82797.1 - 7.7 5.8 10.4 0.6 9.4 2.1 2.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Spc24 PF08286.11 ETS82797.1 - 8.1 6.7 9.6 2.9 8.2 0.7 2.8 3 0 0 3 3 2 0 Spc24 subunit of Ndc80 PRKG1_interact PF15898.5 ETS82797.1 - 8.8 7.3 11.7 1.2 10.1 3.6 3.2 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain HIT PF01230.23 ETS82798.1 - 8.5e-24 84.1 0.1 1.4e-23 83.5 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 ETS82798.1 - 1.3e-05 25.7 0.3 0.00014 22.3 0.3 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AAA PF00004.29 ETS82799.1 - 9.3e-12 45.5 0.0 1.9e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS82799.1 - 1.7e-06 28.4 0.0 4.5e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 ETS82799.1 - 9.7e-06 25.6 0.0 2.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 ETS82799.1 - 9.2e-05 22.5 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ETS82799.1 - 0.00011 22.0 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 ETS82799.1 - 0.00031 20.9 0.1 0.001 19.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 ETS82799.1 - 0.0011 19.4 0.0 0.0027 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 ETS82799.1 - 0.0014 18.7 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ETS82799.1 - 0.0042 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ETS82799.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 ETS82799.1 - 0.012 16.2 0.0 0.033 14.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ETS82799.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 ETS82799.1 - 0.035 14.0 0.0 0.093 12.6 0.0 1.8 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 ETS82799.1 - 0.039 13.7 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ETS82799.1 - 0.054 14.0 0.1 0.16 12.5 0.1 1.9 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 ETS82799.1 - 0.063 12.9 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ETS82799.1 - 0.081 12.4 0.1 0.38 10.2 0.0 2.1 3 0 0 3 3 3 0 P-loop containing dynein motor region TsaE PF02367.17 ETS82799.1 - 0.099 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 ETS82799.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_19 PF13245.6 ETS82799.1 - 0.11 12.8 0.7 1.1 9.6 0.7 2.3 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.16 ETS82801.1 - 1.6e-26 93.1 27.9 2.3e-18 66.3 12.8 3.0 2 1 0 3 3 3 3 Major Facilitator Superfamily OATP PF03137.20 ETS82801.1 - 0.0014 17.0 2.2 0.022 13.1 2.1 2.3 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Ferrochelatase PF00762.19 ETS82802.1 - 1e-98 330.4 0.0 1.2e-98 330.1 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ku PF02735.16 ETS82803.1 - 1.2e-42 146.0 0.0 3.4e-42 144.5 0.0 1.8 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 ETS82803.1 - 6.4e-29 101.3 0.0 9.4e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 ETS82803.1 - 7.9e-22 77.8 4.1 2.3e-21 76.3 4.1 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 ETS82803.1 - 1.5e-14 53.4 0.4 2.9e-14 52.4 0.4 1.5 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 ETS82803.1 - 2.1e-05 24.1 0.4 2.1e-05 24.1 0.4 1.8 2 0 0 2 2 2 1 HeH/LEM domain RNA_POL_M_15KD PF02150.16 ETS82804.1 - 0.0037 17.1 0.5 1.6 8.7 0.1 2.4 2 0 0 2 2 2 2 RNA polymerases M/15 Kd subunit zinc_ribbon_6 PF14599.6 ETS82804.1 - 0.51 10.4 2.0 2.9 8.0 0.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon Zn_clus PF00172.18 ETS82805.1 - 5.3e-07 29.7 9.5 9.4e-07 28.9 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.20 ETS82806.1 - 8.9e-76 255.4 0.0 3.5e-60 204.2 0.0 2.0 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 ETS82806.1 - 2.7e-06 27.2 5.6 9.7e-05 22.0 1.2 2.4 2 1 0 2 2 2 2 Amidohydrolase family DUF1729 PF08354.10 ETS82807.1 - 2.1e-159 530.1 0.0 3.3e-159 529.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 ETS82807.1 - 2.1e-89 300.2 0.0 2.4e-88 296.7 0.0 2.8 3 0 0 3 3 3 1 Acyl transferase domain FAS_meander PF17951.1 ETS82807.1 - 8.9e-54 181.3 0.0 2.3e-53 179.9 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 ETS82807.1 - 7.6e-39 132.7 0.0 3.3e-38 130.6 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 ETS82807.1 - 7.1e-38 128.9 0.0 1.5e-37 127.9 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 ETS82807.1 - 1.4e-35 123.2 0.0 4e-35 121.7 0.0 1.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 ETS82807.1 - 2.4e-24 85.9 0.0 1e-23 83.9 0.0 2.2 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase PCIF1_WW PF12237.8 ETS82807.1 - 0.026 14.1 0.0 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Phosphorylated CTD interacting factor 1 WW domain MCRS_N PF13325.6 ETS82807.1 - 0.083 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein FAS_I_H PF18314.1 ETS82808.1 - 4e-77 258.5 0.3 9.3e-77 257.2 0.0 1.8 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 ETS82808.1 - 4.3e-76 254.7 0.0 8.3e-76 253.8 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 ETS82808.1 - 1.9e-20 73.6 0.0 4.2e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 ETS82808.1 - 1.2e-18 67.3 0.0 2.9e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 ETS82808.1 - 8.7e-12 45.1 0.2 3.7e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 ETS82808.1 - 1.1e-05 25.0 0.0 3.7e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS82808.1 - 0.00016 21.7 0.0 0.0006 19.8 0.0 2.1 1 0 0 1 1 1 1 KR domain Abhydrolase_6 PF12697.7 ETS82809.1 - 4.7e-15 56.8 0.0 5.4e-15 56.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 ETS82809.1 - 0.019 14.6 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Lambda_tail_I PF06805.12 ETS82809.1 - 0.039 14.3 0.1 0.071 13.5 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I adh_short PF00106.25 ETS82810.1 - 3.3e-05 23.4 0.0 0.00016 21.2 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Lactamase_B_2 PF12706.7 ETS82812.1 - 1.2e-05 25.0 0.1 2.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ETS82812.1 - 1.2e-05 25.3 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MFS_1 PF07690.16 ETS82813.1 - 8.8e-41 140.0 41.7 8.8e-41 140.0 41.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS82813.1 - 1.7e-07 30.1 3.3 1.7e-07 30.1 3.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS82813.1 - 1.8e-06 27.1 27.8 5.4e-06 25.5 27.8 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter Oxidored_FMN PF00724.20 ETS82814.1 - 5.6e-97 325.1 0.0 6.4e-97 324.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 ETS82814.1 - 0.044 13.2 0.0 1.4 8.3 0.0 2.3 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Peptidase_M43 PF05572.13 ETS82815.1 - 1.6e-16 60.6 0.9 3.3e-16 59.6 0.4 1.8 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 ETS82815.1 - 4.8e-06 26.9 0.5 7.6e-06 26.2 0.4 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 ETS82815.1 - 4.2e-05 23.3 0.1 6.9e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 ETS82815.1 - 0.00013 22.4 0.1 0.00032 21.2 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 ETS82815.1 - 0.00021 21.1 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.6 ETS82815.1 - 0.0024 17.8 0.1 0.0037 17.2 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 ETS82815.1 - 0.0043 16.1 0.3 0.0073 15.3 0.3 1.4 1 0 0 1 1 1 1 Peptidase M66 DUF4953 PF16313.5 ETS82815.1 - 0.059 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Met-zincin Arf PF00025.21 ETS82816.1 - 1.4e-27 96.2 0.0 1.9e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ETS82816.1 - 0.024 14.1 0.0 0.14 11.6 0.0 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 ETS82816.1 - 0.025 14.8 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 ETS82816.1 - 0.061 13.7 0.1 0.59 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain CorA PF01544.18 ETS82816.1 - 0.097 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Protocadherin PF08374.11 ETS82817.1 - 0.00019 21.5 0.1 0.00019 21.5 0.1 1.5 2 0 0 2 2 1 1 Protocadherin Plasmodium_Vir PF05795.11 ETS82817.1 - 0.00051 19.6 0.2 0.00066 19.2 0.2 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Syndecan PF01034.20 ETS82817.1 - 0.0006 19.7 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain TMEM154 PF15102.6 ETS82817.1 - 0.00064 19.6 0.2 0.0012 18.7 0.2 1.5 1 0 0 1 1 1 1 TMEM154 protein family Hum_adeno_E3A PF05393.11 ETS82817.1 - 0.0015 18.4 0.2 0.0077 16.2 0.1 2.1 2 0 0 2 2 2 1 Human adenovirus early E3A glycoprotein EphA2_TM PF14575.6 ETS82817.1 - 0.0029 18.4 0.7 0.0097 16.8 0.7 1.9 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 ETS82817.1 - 0.0051 16.5 0.2 0.011 15.5 0.2 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Orthoreo_P10 PF07204.11 ETS82817.1 - 0.019 14.9 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 UL41A PF17591.2 ETS82817.1 - 0.03 14.4 0.0 0.07 13.2 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus UL41A Serinc PF03348.15 ETS82817.1 - 0.032 13.2 0.7 0.044 12.7 0.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4834 PF16118.5 ETS82817.1 - 0.078 14.0 0.7 0.3 12.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SKG6 PF08693.10 ETS82817.1 - 0.083 12.3 0.2 0.21 11.1 0.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Presenilin PF01080.17 ETS82817.1 - 0.089 11.5 0.3 0.13 11.0 0.3 1.2 1 0 0 1 1 1 0 Presenilin MAP17 PF15807.5 ETS82817.1 - 0.13 12.5 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Gly-zipper_Omp PF13488.6 ETS82817.1 - 0.13 12.3 3.2 0.28 11.2 3.2 1.5 1 0 0 1 1 1 0 Glycine zipper FAM176 PF14851.6 ETS82817.1 - 0.13 11.9 0.5 0.22 11.2 0.1 1.5 2 0 0 2 2 2 0 FAM176 family Herpes_glycop PF01528.16 ETS82817.1 - 0.22 10.4 0.5 0.33 9.8 0.3 1.3 1 1 0 1 1 1 0 Herpesvirus glycoprotein M BIR PF00653.21 ETS82819.1 - 1.3e-44 150.7 2.7 1.9e-22 79.7 1.8 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain AT_hook PF02178.19 ETS82819.1 - 0.00022 20.7 5.5 0.086 12.8 3.4 4.4 2 0 0 2 2 2 2 AT hook motif GST_N_3 PF13417.6 ETS82820.1 - 1.7e-10 41.2 0.0 3.9e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ETS82820.1 - 1e-07 32.1 0.0 1.9e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS82820.1 - 6.6e-06 26.1 0.0 5.1e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ETS82820.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PAS_4 PF08448.10 ETS82820.1 - 0.017 15.4 0.1 0.029 14.6 0.1 1.4 1 0 0 1 1 1 0 PAS fold Promethin PF16015.5 ETS82822.1 - 0.45 10.5 6.7 0.73 9.8 0.1 2.7 3 0 0 3 3 3 0 Promethin Clr5 PF14420.6 ETS82823.1 - 4.5e-14 52.4 0.6 4.5e-14 52.4 0.6 2.1 2 0 0 2 2 2 1 Clr5 domain HET PF06985.11 ETS82824.1 - 1e-31 110.3 2.5 2.1e-31 109.2 1.7 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_18 PF00704.28 ETS82826.1 - 9.9e-65 219.3 4.0 4.4e-64 217.2 1.5 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ETS82826.1 - 8.8e-12 45.3 20.1 8.8e-12 45.3 20.1 5.1 5 0 0 5 5 5 2 Chitin recognition protein DNase_NucA_NucB PF14040.6 ETS82826.1 - 5.2e-06 26.8 3.1 0.00048 20.5 0.0 3.9 4 0 0 4 4 4 1 Deoxyribonuclease NucA/NucB LysM PF01476.20 ETS82828.1 - 1.9e-23 82.2 1.3 0.00015 21.7 0.0 5.5 5 0 0 5 5 5 5 LysM domain Ferritin_2 PF13668.6 ETS82829.1 - 1.8e-06 28.2 0.1 3e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain Glyco_transf_22 PF03901.17 ETS82832.1 - 2.3e-84 284.1 16.2 2.6e-84 283.9 16.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.14 ETS82833.1 - 5e-42 143.3 0.8 1.2e-41 142.0 0.8 1.6 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region YL1 PF05764.13 ETS82833.1 - 1.1 9.4 13.7 6.9 6.7 0.4 2.6 2 0 0 2 2 2 0 YL1 nuclear protein Na_trans_assoc PF06512.13 ETS82833.1 - 2.1 8.6 12.9 2.5 8.3 9.5 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated Endomucin PF07010.12 ETS82833.1 - 2.3 8.1 10.7 4.7 7.1 10.7 1.5 1 0 0 1 1 1 0 Endomucin FAD_binding_3 PF01494.19 ETS82835.1 - 6.2e-12 45.4 0.0 8.2e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 ETS82835.1 - 0.011 14.8 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase FAD_binding_3 PF01494.19 ETS82836.1 - 3.8e-05 23.1 0.2 7e-05 22.2 0.2 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ETS82836.1 - 0.027 14.7 0.1 0.058 13.6 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS82836.1 - 0.1 12.6 0.4 1.2 9.1 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_10 PF13460.6 ETS82837.1 - 3.6e-17 62.8 0.0 1.1e-16 61.2 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 ETS82837.1 - 6.2e-17 61.9 0.2 8.2e-17 61.5 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ETS82837.1 - 0.008 15.7 0.0 0.54 9.7 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family ThiP_synth PF10120.9 ETS82837.1 - 0.12 11.9 0.1 0.45 10.1 0.0 1.9 2 0 0 2 2 2 0 Thiamine-phosphate synthase Clr5 PF14420.6 ETS82838.1 - 1.9e-17 63.2 1.3 1.2e-16 60.6 0.9 2.5 2 0 0 2 2 2 1 Clr5 domain LtrA PF06772.11 ETS82839.1 - 1.7e-15 57.1 26.7 1.7e-15 57.1 26.7 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Acyl-CoA_dh_1 PF00441.24 ETS82840.1 - 2.5e-41 141.4 4.0 4e-41 140.7 4.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ETS82840.1 - 1.4e-28 99.8 0.3 3.8e-28 98.4 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ETS82840.1 - 6.9e-24 83.9 0.0 1.4e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ETS82840.1 - 4.8e-18 65.7 0.7 8.2e-18 65.0 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ETS82840.1 - 0.00026 20.7 0.1 0.00066 19.4 0.1 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Ribosom_S12_S23 PF00164.25 ETS82841.1 - 9e-31 105.8 0.4 1.2e-30 105.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Peptidase_C13 PF01650.18 ETS82842.1 - 3.9e-41 141.3 0.2 5e-41 140.9 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family TFIIIC_delta PF12657.7 ETS82843.1 - 1.8e-22 80.1 0.0 5.8e-22 78.5 0.0 1.9 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 ETS82843.1 - 3.9e-11 42.8 2.3 8.8e-11 41.7 1.5 2.1 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex DUF3481 PF11980.8 ETS82844.1 - 0.0051 16.5 0.2 0.0073 16.0 0.2 1.3 1 0 0 1 1 1 1 C-terminal domain of neuropilin glycoprotein DUF4713 PF15831.5 ETS82844.1 - 0.0079 16.6 2.1 0.01 16.2 1.4 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4713) Prominin PF05478.11 ETS82844.1 - 0.15 10.0 0.0 0.15 10.0 0.0 1.1 1 0 0 1 1 1 0 Prominin HAUS6_N PF14661.6 ETS82847.1 - 3e-56 190.6 1.8 3e-56 190.6 1.8 2.2 3 0 0 3 3 3 1 HAUS augmin-like complex subunit 6 N-terminus Fungal_trans PF04082.18 ETS82848.1 - 9.5e-11 41.2 0.1 2.5e-10 39.8 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 ETS82849.1 - 6.5e-22 77.9 0.2 1.6e-21 76.7 0.2 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS82849.1 - 6.2e-13 49.1 0.2 1.2e-12 48.1 0.2 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ETS82849.1 - 1.1e-10 41.5 0.1 3.9e-10 39.7 0.1 1.8 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ETS82849.1 - 5.1e-08 32.7 0.0 8.2e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ETS82849.1 - 6.8e-05 22.2 0.1 0.00078 18.7 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ETS82849.1 - 0.0002 20.6 0.4 0.0016 17.7 0.2 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 ETS82849.1 - 0.00054 20.0 0.0 0.00095 19.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 ETS82849.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ETS82849.1 - 0.0012 17.9 0.2 0.002 17.2 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CRCB PF02537.15 ETS82849.1 - 0.0077 16.5 0.1 0.026 14.8 0.1 1.8 1 1 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) Turandot PF07240.11 ETS82849.1 - 0.017 15.1 0.1 0.28 11.2 0.0 2.3 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot RmlD_sub_bind PF04321.17 ETS82849.1 - 0.067 12.3 0.1 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 ETS82849.1 - 0.075 12.9 0.3 0.14 12.0 0.1 1.6 2 0 0 2 2 2 0 NAD(P)H-binding NmrA PF05368.13 ETS82850.1 - 8.2e-16 58.3 0.0 1e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS82850.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Med17 PF10156.9 ETS82850.1 - 0.049 12.3 0.0 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex FMO-like PF00743.19 ETS82852.1 - 1.2e-12 47.1 0.7 5.3e-11 41.6 0.0 2.4 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ETS82852.1 - 5.4e-12 45.6 0.0 1.4e-09 37.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS82852.1 - 2.3e-09 36.9 0.0 1.6e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ETS82852.1 - 7.3e-08 32.0 0.0 1.4e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS82852.1 - 1.5e-07 31.5 0.0 7.7e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ETS82852.1 - 1.3e-05 25.7 1.1 0.012 16.2 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ETS82852.1 - 0.00042 20.4 0.5 0.14 12.2 0.1 3.2 4 0 0 4 4 4 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 ETS82852.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 ETS82852.1 - 0.0034 17.4 0.2 3.5 7.6 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 ETS82852.1 - 0.0067 16.0 0.2 7 6.1 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 ETS82852.1 - 0.042 14.3 0.1 2.7 8.5 0.1 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 ETS82852.1 - 0.068 12.2 0.6 2.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 ETS82852.1 - 0.12 11.5 0.5 2 7.6 0.0 2.4 3 0 0 3 3 3 0 Thi4 family IlvN PF07991.12 ETS82852.1 - 0.16 11.5 1.3 1.3 8.6 0.1 2.4 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 ETS82852.1 - 0.26 10.3 3.7 22 4.0 0.0 3.0 3 0 0 3 3 3 0 Glucose inhibited division protein A TrkA_N PF02254.18 ETS82852.1 - 0.48 10.7 1.2 4.7 7.5 0.0 2.9 4 0 0 4 4 3 0 TrkA-N domain Abhydrolase_3 PF07859.13 ETS82853.1 - 6.1e-10 39.3 0.3 7.1e-09 35.8 0.2 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS82853.1 - 1.4e-08 34.5 0.0 2.7e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 ETS82853.1 - 2.7e-07 31.4 4.6 4e-07 30.8 4.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 ETS82853.1 - 0.00018 20.6 0.0 0.00026 20.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.12 ETS82853.1 - 0.00091 18.0 0.4 0.015 14.0 0.1 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Chlorophyllase PF07224.11 ETS82853.1 - 0.0016 17.5 0.0 0.0023 17.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Esterase_phd PF10503.9 ETS82853.1 - 0.0033 16.9 1.6 1.5 8.3 0.0 2.7 3 0 0 3 3 3 2 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 ETS82853.1 - 0.035 13.9 0.0 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 ETS82853.1 - 0.11 12.6 0.0 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 TAP-like protein MoCF_biosynth PF00994.24 ETS82854.1 - 1.4e-21 76.7 0.0 2.8e-21 75.7 0.0 1.5 1 1 0 1 1 1 1 Probable molybdopterin binding domain CinA_KH PF18146.1 ETS82854.1 - 0.033 14.4 0.0 0.071 13.3 0.0 1.6 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain Cofilin_ADF PF00241.20 ETS82855.1 - 6.5e-18 64.7 0.0 8.3e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1657 PF07870.11 ETS82855.1 - 0.04 13.8 0.3 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) ParA PF10609.9 ETS82856.1 - 3.6e-96 321.4 0.0 4.6e-96 321.0 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 ETS82856.1 - 5.3e-08 33.0 0.0 1.3e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ETS82856.1 - 0.00037 20.5 0.0 0.0029 17.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 ETS82856.1 - 0.0004 19.7 0.7 0.0022 17.3 0.4 2.1 1 1 1 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 ETS82856.1 - 0.017 14.7 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ETS82856.1 - 0.027 14.4 0.1 0.047 13.6 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_26 PF13500.6 ETS82856.1 - 0.029 14.2 0.0 0.46 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain CBP_BcsQ PF06564.12 ETS82856.1 - 0.043 13.3 0.0 0.48 9.9 0.0 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 ETS82856.1 - 0.063 12.7 0.0 1.7 8.0 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirE PF05272.11 ETS82856.1 - 0.091 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E MipZ PF09140.11 ETS82856.1 - 0.11 11.7 0.0 0.24 10.7 0.0 1.6 1 1 0 1 1 1 0 ATPase MipZ CLP1_P PF16575.5 ETS82856.1 - 0.15 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Glyco_hydro_28 PF00295.17 ETS82857.1 - 1.6e-11 43.9 2.0 2.6e-11 43.2 2.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 ETS82857.1 - 0.00055 19.8 15.5 0.021 14.7 12.7 3.0 1 1 0 1 1 1 1 Right handed beta helix region DUF2577 PF10844.8 ETS82857.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2577) Alginate_lyase PF05426.12 ETS82858.1 - 4e-14 52.8 1.4 1.3e-13 51.1 1.4 1.7 1 1 0 1 1 1 1 Alginate lyase Hist_deacetyl PF00850.19 ETS82859.1 - 2.4e-52 178.3 0.1 4.2e-52 177.5 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Shugoshin_C PF07557.11 ETS82859.1 - 0.028 14.2 1.1 0.15 11.9 1.1 2.3 1 0 0 1 1 1 0 Shugoshin C terminus Adaptin_binding PF10199.9 ETS82859.1 - 0.03 14.9 0.3 0.11 13.0 0.3 2.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 RTP801_C PF07809.11 ETS82859.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 RTP801 C-terminal region Cutinase PF01083.22 ETS82860.1 - 2.9e-27 95.7 0.6 2.9e-27 95.7 0.6 1.8 3 0 0 3 3 3 1 Cutinase MGC-24 PF05283.11 ETS82860.1 - 1.5 9.2 9.2 4.3 7.8 9.2 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DHquinase_I PF01487.15 ETS82861.1 - 8.3e-44 150.5 0.0 9.9e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Type I 3-dehydroquinase SDH_C PF18317.1 ETS82861.1 - 0.0017 18.1 0.0 0.0081 15.9 0.0 2.1 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain PGI PF00342.19 ETS82862.1 - 1.4e-226 752.8 0.3 1.6e-226 752.6 0.3 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Asparaginase_II PF06089.12 ETS82863.1 - 2.1e-113 378.6 1.1 2.4e-113 378.4 1.1 1.0 1 0 0 1 1 1 1 L-asparaginase II Rep_N PF08724.10 ETS82864.1 - 0.00079 19.2 0.0 0.015 15.0 0.0 2.3 2 0 0 2 2 2 1 Rep protein catalytic domain like zf-C2H2_4 PF13894.6 ETS82864.1 - 0.14 13.0 1.0 1.8 9.6 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger HET PF06985.11 ETS82865.1 - 2.1e-28 99.5 0.6 3.2e-28 98.9 0.6 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GrpB PF04229.14 ETS82865.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 GrpB protein Cutinase PF01083.22 ETS82866.1 - 2.5e-41 141.6 0.0 3.1e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Cutinase Hydrolase_4 PF12146.8 ETS82866.1 - 0.02 14.2 0.3 0.088 12.1 0.2 1.9 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 ETS82866.1 - 0.044 13.6 0.1 0.063 13.1 0.1 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 ETS82866.1 - 0.045 13.4 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.11 ETS82866.1 - 0.048 13.2 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain VirJ PF06057.11 ETS82866.1 - 0.049 13.5 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Palm_thioest PF02089.15 ETS82866.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF2577 PF10844.8 ETS82866.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2577) F-box-like PF12937.7 ETS82867.1 - 0.0035 17.2 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 F-box-like Exo5 PF09810.9 ETS82868.1 - 1.2e-116 390.2 0.0 2.3e-116 389.3 0.0 1.4 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PAS_9 PF13426.7 ETS82869.1 - 1.4e-17 63.8 0.0 2.5e-14 53.4 0.0 2.6 2 0 0 2 2 2 2 PAS domain RGS PF00615.19 ETS82869.1 - 1e-07 32.2 0.0 2.7e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS_4 PF08448.10 ETS82869.1 - 5.4e-05 23.4 0.0 0.012 15.9 0.0 3.1 3 0 0 3 3 3 1 PAS fold PAS_3 PF08447.12 ETS82869.1 - 0.012 15.9 0.0 0.059 13.7 0.0 2.1 2 0 0 2 2 2 0 PAS fold LIX1 PF14954.6 ETS82869.1 - 0.015 14.6 0.2 0.025 13.9 0.2 1.3 1 0 0 1 1 1 0 Limb expression 1 PAS PF00989.25 ETS82869.1 - 0.029 14.4 0.0 0.19 11.8 0.0 2.3 3 0 0 3 3 3 0 PAS fold PRIMA1 PF16101.5 ETS82869.1 - 0.87 9.6 8.7 0.99 9.4 0.2 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Glyco_transf_90 PF05686.12 ETS82870.1 - 1.7e-13 50.2 0.0 3.9e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 90 Esterase_phd PF10503.9 ETS82871.1 - 1.6e-21 76.8 0.1 2.4e-21 76.3 0.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ETS82871.1 - 8.8e-05 22.1 0.2 0.00014 21.5 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ETS82871.1 - 0.0057 16.3 0.5 0.011 15.4 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 ETS82871.1 - 0.041 13.7 0.1 0.06 13.2 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 ETS82871.1 - 0.11 12.1 2.7 0.21 11.2 2.7 1.6 1 1 0 1 1 1 0 Putative esterase ABC2_membrane PF01061.24 ETS82872.1 - 1.4e-73 246.8 45.1 3.5e-40 137.7 22.7 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 ETS82872.1 - 7.5e-44 149.6 0.1 2.3e-22 80.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ETS82872.1 - 5.6e-22 77.4 0.1 5.9e-18 64.6 0.0 3.2 2 0 0 2 2 2 2 CDR ABC transporter SMC_N PF02463.19 ETS82872.1 - 1e-06 28.4 0.0 0.12 11.8 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ETS82872.1 - 1.7e-05 24.8 0.5 0.00012 22.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ETS82872.1 - 2.2e-05 24.9 0.2 0.015 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 ETS82872.1 - 0.00011 21.5 38.2 0.00073 18.7 22.1 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 ETS82872.1 - 0.00034 20.5 0.0 0.47 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ETS82872.1 - 0.0016 18.1 1.0 0.054 13.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ETS82872.1 - 0.0066 16.7 0.1 0.58 10.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 ETS82872.1 - 0.0068 17.0 0.6 1.7 9.2 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 ETS82872.1 - 0.0093 15.7 0.1 0.58 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 ETS82872.1 - 0.0098 15.8 0.0 3.3 7.6 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea DUF2931 PF11153.8 ETS82872.1 - 0.015 15.0 0.1 0.21 11.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2931) AAA_19 PF13245.6 ETS82872.1 - 0.017 15.4 0.3 1.8 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ETS82872.1 - 0.022 14.7 0.2 0.71 9.8 0.1 2.7 3 0 0 3 3 2 0 NACHT domain cobW PF02492.19 ETS82872.1 - 0.051 13.2 0.1 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 ETS82872.1 - 0.06 13.4 0.0 3.5 7.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.6 ETS82872.1 - 0.061 12.9 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ETS82872.1 - 0.061 13.5 0.0 0.22 11.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain PduV-EutP PF10662.9 ETS82872.1 - 0.065 13.0 0.1 1.7 8.4 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 ETS82872.1 - 0.068 13.6 0.0 13 6.2 0.0 3.4 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) UPF0449 PF15136.6 ETS82872.1 - 0.07 13.6 0.1 0.17 12.4 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Roc PF08477.13 ETS82872.1 - 0.09 13.0 0.1 5.9 7.1 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 ETS82872.1 - 0.11 12.5 0.2 0.31 11.0 0.1 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 ETS82872.1 - 0.11 12.7 0.1 0.46 10.7 0.1 2.1 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.22 ETS82872.1 - 0.13 11.4 0.4 5.3 6.1 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain Fungal_trans PF04082.18 ETS82873.1 - 2.2e-16 59.7 1.3 3.2e-16 59.2 0.5 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS82873.1 - 2.8e-08 33.7 12.9 5.5e-08 32.8 12.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HHH_6 PF14579.6 ETS82873.1 - 0.16 12.3 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Ank_2 PF12796.7 ETS82874.1 - 1e-74 247.1 1.0 4.5e-12 46.4 0.0 13.0 6 2 6 14 14 14 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS82874.1 - 4.1e-58 193.1 12.8 5.3e-07 30.1 0.0 15.9 11 3 5 16 16 16 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS82874.1 - 1.8e-49 165.1 18.0 1.7e-11 44.1 0.2 17.0 12 4 6 18 18 18 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS82874.1 - 1.7e-48 156.9 12.0 0.0029 18.0 0.0 20.6 21 0 0 21 21 21 11 Ankyrin repeat Ank PF00023.30 ETS82874.1 - 7.1e-44 146.4 19.0 0.0042 17.5 0.0 17.8 18 0 0 18 18 18 10 Ankyrin repeat Arylsulfotran_2 PF14269.6 ETS82875.1 - 9e-67 225.5 9.6 1.2e-66 225.1 9.6 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 ETS82875.1 - 4.8e-13 48.8 8.2 4.7e-12 45.5 8.2 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF2236 PF09995.9 ETS82877.1 - 2.3e-44 152.3 2.7 3e-44 151.9 2.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Polysacc_lyase PF14099.6 ETS82878.1 - 2.5e-19 70.0 0.3 3.1e-19 69.6 0.3 1.2 1 0 0 1 1 1 1 Polysaccharide lyase TauD PF02668.16 ETS82879.1 - 7.4e-51 173.5 0.8 1e-50 173.0 0.8 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1993 PF09351.10 ETS82880.1 - 1.3e-48 165.2 0.1 1.4e-48 165.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Ribosomal_L22 PF00237.19 ETS82880.1 - 0.17 12.1 0.2 1.2 9.4 0.0 2.1 2 1 0 2 2 2 0 Ribosomal protein L22p/L17e Ras PF00071.22 ETS82881.1 - 2.5e-59 199.5 0.2 3e-59 199.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS82881.1 - 8.2e-20 71.2 0.0 1.3e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS82881.1 - 2.1e-07 30.6 0.0 2.3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ETS82881.1 - 0.00012 22.0 0.4 0.46 10.4 0.0 2.4 1 1 1 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 ETS82881.1 - 0.00012 21.7 0.1 0.0011 18.5 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 ETS82881.1 - 0.0019 18.2 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 ETS82881.1 - 0.0049 17.0 0.0 0.0074 16.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ETS82881.1 - 0.0068 15.9 0.0 0.023 14.2 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 ETS82881.1 - 0.11 12.3 1.7 1.1 9.0 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein HC2 PF07382.11 ETS82882.1 - 6.6e-06 26.3 27.2 6.6e-06 26.3 27.2 1.7 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 CENP-B_dimeris PF09026.10 ETS82882.1 - 0.002 18.5 3.8 0.002 18.5 3.8 2.8 2 0 0 2 2 2 1 Centromere protein B dimerisation domain TcpQ PF10671.9 ETS82882.1 - 0.45 10.7 4.0 0.44 10.7 1.6 2.1 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q Cwf_Cwc_15 PF04889.12 ETS82882.1 - 7.5 6.2 37.6 6.1 6.5 10.1 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CDC27 PF09507.10 ETS82882.1 - 9.4 5.5 32.6 1 8.7 18.3 2.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Peptidase_M20 PF01546.28 ETS82883.1 - 5.4e-32 111.2 0.1 1.1e-31 110.2 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ETS82883.1 - 6.7e-20 71.0 0.1 1.4e-19 70.0 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ETS82883.1 - 6.2e-05 22.8 0.0 0.00024 20.9 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 Anp1 PF03452.14 ETS82884.1 - 4.3e-29 101.8 0.0 5.6e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Anp1 Acetyltransf_7 PF13508.7 ETS82885.1 - 1.4e-07 31.8 0.0 2.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS82885.1 - 6.6e-07 29.6 0.0 8.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS82885.1 - 3.2e-05 23.9 0.0 0.00024 21.1 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain His_Phos_2 PF00328.22 ETS82887.1 - 1.7e-41 142.8 0.0 7.9e-41 140.7 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_S9 PF00326.21 ETS82889.1 - 8.7e-20 71.1 0.0 1.4e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ETS82889.1 - 5.3e-09 36.3 0.1 4.7e-08 33.2 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 ETS82889.1 - 3e-05 23.8 0.0 0.031 13.9 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 ETS82889.1 - 0.00014 21.5 0.0 0.00044 19.9 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF2048 PF09752.9 ETS82889.1 - 0.075 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 p450 PF00067.22 ETS82892.1 - 3.2e-49 167.9 0.0 4.3e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Na_Ca_ex PF01699.24 ETS82893.1 - 7.6e-43 146.1 34.0 9.9e-22 77.5 17.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein SpoIIIAH PF12685.7 ETS82893.1 - 0.18 11.6 1.5 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein PGA2 PF07543.12 ETS82893.1 - 0.25 11.3 5.3 1 9.3 0.1 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 TFIIE-A_C PF11521.8 ETS82893.1 - 0.68 10.3 3.7 0.48 10.8 0.8 2.0 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DUF3169 PF11368.8 ETS82893.1 - 3.7 7.0 11.7 1.4 8.4 0.3 3.1 3 2 0 3 3 3 0 Protein of unknown function (DUF3169) IML1 PF12257.8 ETS82894.1 - 6.6e-116 386.4 0.1 9.5e-116 385.9 0.1 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 ETS82894.1 - 7.9e-27 93.1 0.1 1.8e-26 92.0 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) adh_short PF00106.25 ETS82895.1 - 1.7e-28 99.4 0.7 8.4e-25 87.4 0.9 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS82895.1 - 5.5e-18 65.4 0.1 4.2e-16 59.2 0.3 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS82895.1 - 5.3e-08 33.0 0.2 1.1e-07 31.9 0.2 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS82895.1 - 0.00054 19.2 0.1 0.00087 18.5 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 ETS82895.1 - 0.0031 17.0 0.2 0.0065 16.0 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family MoCF_biosynth PF00994.24 ETS82895.1 - 0.14 11.8 0.1 0.92 9.2 0.0 2.1 2 0 0 2 2 2 0 Probable molybdopterin binding domain Cation_efflux PF01545.21 ETS82896.1 - 7.6e-45 153.1 1.0 1.1e-44 152.6 1.0 1.2 1 0 0 1 1 1 1 Cation efflux family FNIP_N PF14636.6 ETS82897.1 - 6.8e-41 140.8 0.7 6.8e-41 140.8 0.7 4.7 4 2 0 4 4 4 1 Folliculin-interacting protein N-terminus Tyrosinase PF00264.20 ETS82898.1 - 1.3e-33 117.1 7.1 2.9e-32 112.7 7.1 2.1 1 1 0 1 1 1 1 Common central domain of tyrosinase AAA PF00004.29 ETS82900.1 - 4.1e-19 69.3 0.0 4.8e-18 65.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS82900.1 - 0.0016 18.7 1.7 0.07 13.4 0.1 3.2 1 1 2 3 3 3 1 AAA domain AAA_16 PF13191.6 ETS82900.1 - 0.0022 18.4 0.1 0.0065 16.9 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 ETS82900.1 - 0.028 14.2 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ETS82900.1 - 0.054 13.2 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 ETS82900.1 - 0.093 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ETS82900.1 - 0.1 12.6 0.2 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 ETS82900.1 - 0.19 12.0 0.1 1 9.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain Glyco_hydro_61 PF03443.14 ETS82901.1 - 1.5e-55 188.4 0.0 1.7e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fungal_trans_2 PF11951.8 ETS82902.1 - 4.7e-28 98.1 0.0 1.4e-27 96.5 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS82902.1 - 1.6e-07 31.3 2.7 2.7e-07 30.6 2.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M24 PF00557.24 ETS82903.1 - 2.1e-41 141.9 0.0 3.9e-27 95.3 0.0 2.3 2 0 0 2 2 2 2 Metallopeptidase family M24 Creatinase_N PF01321.18 ETS82903.1 - 0.0031 18.1 0.0 0.0063 17.2 0.0 1.6 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Sugar_tr PF00083.24 ETS82904.1 - 3.3e-34 118.5 27.0 3.9e-18 65.6 8.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ETS82904.1 - 2.9e-23 82.4 44.6 4.9e-13 48.7 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS82904.1 - 0.0085 14.7 24.3 0.019 13.6 6.1 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein DUF2231 PF09990.9 ETS82904.1 - 0.15 12.5 5.7 0.51 10.8 5.7 2.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) DUF3328 PF11807.8 ETS82905.1 - 0.0031 17.3 5.2 0.009 15.8 5.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) MAD PF05557.13 ETS82906.1 - 5e-57 193.7 70.8 2.4e-56 191.4 70.6 1.8 1 1 1 2 2 2 2 Mitotic checkpoint protein Tam41_Mmp37 PF09139.11 ETS82907.1 - 8.5e-128 426.3 0.0 1.3e-127 425.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial p450 PF00067.22 ETS82908.1 - 1.9e-42 145.6 0.0 3.8e-42 144.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 LANC_like PF05147.13 ETS82909.1 - 1.9e-29 102.4 0.0 8.9e-29 100.2 0.0 1.9 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein Methyltransf_25 PF13649.6 ETS82910.1 - 2.2e-13 50.7 0.0 3.2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS82910.1 - 2.5e-11 44.2 0.0 3.6e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS82910.1 - 1.9e-10 41.3 0.0 2.9e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS82910.1 - 1.9e-07 31.0 0.0 2.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS82910.1 - 2.8e-07 30.1 0.0 3.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ETS82910.1 - 1e-06 28.7 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS82910.1 - 4.3e-05 23.1 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 ETS82910.1 - 0.00011 21.8 0.0 0.00016 21.2 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase CMAS PF02353.20 ETS82910.1 - 0.00083 18.7 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 ETS82910.1 - 0.0016 17.9 0.0 0.0023 17.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Rsm22 PF09243.10 ETS82910.1 - 0.0023 17.3 0.0 0.0028 17.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Cons_hypoth95 PF03602.15 ETS82910.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Abhydrolase_1 PF00561.20 ETS82911.1 - 7.3e-17 61.8 0.2 1.5e-15 57.6 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS82911.1 - 2.9e-16 60.8 0.0 3.4e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS82911.1 - 1.6e-09 37.4 0.0 5.8e-09 35.6 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1651 PF07864.11 ETS82911.1 - 0.005 17.2 0.9 0.15 12.4 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1651) DUF2974 PF11187.8 ETS82911.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) BNR_6 PF15899.5 ETS82911.1 - 0.013 15.5 0.7 0.74 10.0 0.1 2.9 2 0 0 2 2 2 0 BNR-Asp box repeat DUF900 PF05990.12 ETS82911.1 - 0.014 14.9 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Peptidase_S9 PF00326.21 ETS82911.1 - 0.018 14.5 0.0 0.43 10.0 0.0 2.4 3 0 0 3 3 3 0 Prolyl oligopeptidase family PGAP1 PF07819.13 ETS82911.1 - 0.029 14.1 0.0 0.042 13.6 0.0 1.4 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.13 ETS82911.1 - 0.045 13.6 0.0 0.34 10.7 0.0 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 ETS82911.1 - 0.16 12.1 0.0 0.2 11.7 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain Ran_BP1 PF00638.18 ETS82912.1 - 2.8e-14 53.4 0.0 3.5e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 RanBP1 domain Phosphoprotein PF00922.17 ETS82912.1 - 0.012 15.3 0.8 0.044 13.4 0.8 1.9 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein COMM_domain PF07258.14 ETS82912.1 - 0.047 13.8 0.1 0.098 12.8 0.1 1.6 1 0 0 1 1 1 0 COMM domain Zip PF02535.22 ETS82912.1 - 0.62 9.2 0.0 0.62 9.2 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter p450 PF00067.22 ETS82913.1 - 1.4e-36 126.3 0.2 1e-21 77.3 0.1 2.7 2 1 0 2 2 2 2 Cytochrome P450 Cupin_2 PF07883.11 ETS82914.1 - 5.5e-08 32.4 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain PI-PLC-X PF00388.19 ETS82915.1 - 1.5e-49 167.4 0.0 2.1e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 ETS82915.1 - 2e-35 121.6 0.0 3.5e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 ETS82915.1 - 0.035 14.4 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 C2 domain Ank_2 PF12796.7 ETS82916.1 - 4.1e-39 133.0 16.4 3.9e-05 24.2 0.1 15.1 12 2 5 17 17 17 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS82916.1 - 9.4e-18 64.3 16.9 0.085 13.5 0.0 14.9 16 2 1 17 17 17 4 Ankyrin repeats (many copies) Ank PF00023.30 ETS82916.1 - 1.2e-12 47.7 23.6 0.35 11.4 0.0 15.3 18 0 0 18 18 18 2 Ankyrin repeat Ank_3 PF13606.6 ETS82916.1 - 1.2e-10 40.7 23.1 0.4 11.4 0.0 18.1 26 0 0 26 26 26 2 Ankyrin repeat Ank_5 PF13857.6 ETS82916.1 - 4.8e-09 36.3 8.7 0.0001 22.5 0.0 8.5 9 1 1 10 10 10 1 Ankyrin repeats (many copies) GDP_Man_Dehyd PF16363.5 ETS82917.1 - 1e-49 169.7 0.0 1.8e-49 169.0 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ETS82917.1 - 1.6e-48 165.3 0.0 2e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS82917.1 - 3.7e-18 65.5 0.0 3.2e-17 62.4 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ETS82917.1 - 6.5e-15 55.0 0.0 5.9e-13 48.6 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ETS82917.1 - 2.8e-12 46.4 0.0 3.9e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 ETS82917.1 - 1.6e-09 37.5 0.0 2.5e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS82917.1 - 2.1e-08 34.3 0.0 3.6e-08 33.5 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 ETS82917.1 - 2.1e-07 30.4 0.0 3.2e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 ETS82917.1 - 0.00031 20.7 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 ETS82917.1 - 0.0037 16.9 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.14 ETS82917.1 - 0.025 14.2 0.1 0.046 13.3 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 ETS82917.1 - 0.073 12.6 0.0 0.44 10.1 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family Sad1_UNC PF07738.13 ETS82919.1 - 7.1e-06 26.1 0.0 0.0025 17.8 0.0 2.3 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal BMFP PF04380.13 ETS82919.1 - 0.16 12.5 0.4 0.42 11.1 0.1 1.9 2 0 0 2 2 2 0 Membrane fusogenic activity DEAD PF00270.29 ETS82920.1 - 2.8e-45 154.2 0.0 5.6e-45 153.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS82920.1 - 1.1e-24 86.9 0.0 5e-24 84.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ETS82920.1 - 5.7e-19 68.1 0.0 2.1e-18 66.3 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ETS82920.1 - 2.2e-05 24.5 0.0 2.2e-05 24.5 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PAPS_reduct PF01507.19 ETS82921.1 - 9.7e-33 113.6 0.0 4.9e-29 101.6 0.0 2.4 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family BRCT PF00533.26 ETS82922.1 - 6.1e-05 23.3 0.0 0.0001 22.6 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain GEN1_C PF18380.1 ETS82922.1 - 0.098 13.6 14.7 0.92 10.4 4.6 2.4 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain RXT2_N PF08595.11 ETS82922.1 - 0.13 12.3 11.6 0.32 11.0 4.4 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4611 PF15387.6 ETS82922.1 - 0.3 11.3 20.9 0.28 11.4 9.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 ETS82922.1 - 0.6 10.5 24.8 0.044 14.1 9.9 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 ETS82922.1 - 2 8.8 13.9 2.5 8.6 8.3 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TLP-20 PF06088.11 ETS82922.1 - 3.4 7.5 8.5 1.7 8.5 2.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CPSF100_C PF13299.6 ETS82922.1 - 6.3 6.9 11.0 0.77 9.9 1.6 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal FAM176 PF14851.6 ETS82922.1 - 6.9 6.3 14.9 1.9 8.1 4.9 2.3 2 0 0 2 2 2 0 FAM176 family Sporozoite_P67 PF05642.11 ETS82922.1 - 7.6 4.5 10.4 0.072 11.2 2.8 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen NOA36 PF06524.12 ETS82922.1 - 8.2 5.7 12.2 1.6 8.0 6.6 2.1 2 0 0 2 2 2 0 NOA36 protein DLH PF01738.18 ETS82923.1 - 6.1e-17 61.9 0.0 7.8e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 ETS82923.1 - 0.018 14.5 0.0 0.49 9.8 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_M1 PF01433.20 ETS82924.1 - 4.4e-60 202.9 0.0 6.6e-60 202.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 ETS82924.1 - 1.6e-45 156.0 0.6 2.5e-45 155.4 0.6 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 ETS82924.1 - 4.5e-39 134.6 0.0 1.7e-38 132.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain BCS1_N PF08740.11 ETS82925.1 - 1.3e-37 129.6 1.2 2.2e-37 128.8 1.2 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 ETS82925.1 - 4.8e-22 78.8 0.0 8.4e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ETS82925.1 - 3.8e-05 23.5 0.0 6.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 ETS82925.1 - 0.0016 17.7 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 ETS82925.1 - 0.0017 18.7 0.0 0.0053 17.1 0.0 1.9 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.6 ETS82925.1 - 0.0061 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ETS82925.1 - 0.0087 16.1 0.0 0.027 14.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ETS82925.1 - 0.039 14.5 0.0 0.075 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain YL1_C PF08265.11 ETS82925.1 - 0.064 13.0 0.3 0.15 11.9 0.3 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain IstB_IS21 PF01695.17 ETS82925.1 - 0.082 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 ETS82925.1 - 0.097 12.4 0.0 0.55 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ETS82925.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CVNH PF08881.10 ETS82926.1 - 9.1e-26 90.5 1.1 1.3e-25 90.0 1.1 1.2 1 0 0 1 1 1 1 CVNH domain Dehydrin PF00257.19 ETS82926.1 - 6.6e-05 23.5 2.1 0.0001 22.9 2.1 1.3 1 0 0 1 1 1 1 Dehydrin Rick_17kDa_Anti PF05433.15 ETS82926.1 - 0.0017 18.2 13.7 0.0053 16.6 13.8 1.8 1 1 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 ETS82926.1 - 0.018 15.1 7.2 0.033 14.2 7.2 1.4 1 0 0 1 1 1 0 Glycine zipper DUF456 PF04306.13 ETS82926.1 - 0.1 12.9 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_YMGG PF13441.6 ETS82926.1 - 0.53 10.1 13.0 1.1 9.1 13.0 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper Bacteriocin_IIc PF10439.9 ETS82926.1 - 1.9 8.7 7.5 3.4 7.9 7.5 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide ABC2_membrane PF01061.24 ETS82928.1 - 2.5e-80 268.8 51.3 3.6e-46 157.2 17.4 3.0 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.12 ETS82928.1 - 1.2e-37 127.7 1.1 9e-29 99.2 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 ETS82928.1 - 6.5e-32 110.9 0.0 8.3e-16 58.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 ETS82928.1 - 1.9e-17 63.4 29.7 5.5e-09 35.6 12.5 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 ETS82928.1 - 1.6e-13 51.0 0.1 7.8e-13 48.8 0.1 2.2 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 ETS82928.1 - 1.4e-06 28.9 0.1 0.0011 19.4 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 ETS82928.1 - 3.5e-05 23.5 0.2 0.0041 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ETS82928.1 - 4e-05 23.6 0.0 9.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase cobW PF02492.19 ETS82928.1 - 7.9e-05 22.3 0.1 0.013 15.1 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 ETS82928.1 - 8.6e-05 22.5 0.0 0.33 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ETS82928.1 - 0.00048 20.4 0.3 0.077 13.3 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ETS82928.1 - 0.00066 20.2 0.0 0.02 15.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ETS82928.1 - 0.0017 18.1 0.0 0.15 11.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ETS82928.1 - 0.0017 18.4 0.0 0.29 11.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 ETS82928.1 - 0.0023 17.9 0.1 0.27 11.1 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 ETS82928.1 - 0.0058 16.8 0.0 0.17 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 ETS82928.1 - 0.0099 16.1 1.9 0.022 15.0 0.1 2.6 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.18 ETS82928.1 - 0.015 14.7 0.1 6.1 6.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 ETS82928.1 - 0.015 15.8 3.6 0.59 10.6 0.1 3.1 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 ETS82928.1 - 0.026 15.0 4.0 0.038 14.4 0.0 3.1 4 0 0 4 4 3 0 AAA domain AAA_30 PF13604.6 ETS82928.1 - 0.035 13.8 0.2 0.77 9.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 ETS82928.1 - 0.042 12.9 0.0 1.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA PF00004.29 ETS82928.1 - 0.05 14.0 0.1 8.7 6.8 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 ETS82928.1 - 0.05 13.6 0.3 0.96 9.5 0.3 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 ETS82928.1 - 0.053 13.2 0.5 0.97 9.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain dNK PF01712.19 ETS82928.1 - 0.059 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_19 PF13245.6 ETS82928.1 - 0.1 13.0 0.0 24 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ETS82928.1 - 0.1 13.0 0.0 4.3 7.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Septin PF00735.18 ETS82928.1 - 0.17 11.1 0.5 3.6 6.8 0.1 2.3 2 0 0 2 2 2 0 Septin Spt5_N PF11942.8 ETS82929.1 - 0.35 11.9 6.3 1 10.4 6.3 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF2781 PF10914.8 ETS82931.1 - 7.7e-37 127.0 5.2 8.7e-37 126.8 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Mg_trans_NIPA PF05653.14 ETS82933.1 - 2e-88 296.3 29.0 2.6e-88 295.9 29.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ETS82933.1 - 8.5e-05 22.7 7.5 8.5e-05 22.7 7.5 3.2 3 0 0 3 3 3 1 EamA-like transporter family DUF3248 PF11609.8 ETS82933.1 - 0.041 13.8 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) DUF805 PF05656.14 ETS82933.1 - 6.1 7.3 12.5 3.7 8.0 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Clr5 PF14420.6 ETS82935.1 - 2.2e-17 63.0 0.3 5.6e-17 61.7 0.3 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 ETS82935.1 - 2.7 8.4 4.5 38 4.7 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat U-box PF04564.15 ETS82936.1 - 3.5e-20 71.9 0.0 7e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 ETS82936.1 - 1.3e-10 40.6 3.6 0.0049 16.6 0.8 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 ETS82936.1 - 1.6e-07 30.9 5.2 0.00084 19.3 0.8 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ETS82936.1 - 7e-07 29.8 1.6 0.023 15.3 0.2 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS82936.1 - 3.5e-06 27.1 1.5 6.7e-06 26.2 1.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 ETS82936.1 - 4.7e-06 27.0 5.6 0.0096 16.4 0.2 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 ETS82936.1 - 4.8e-06 26.1 3.7 0.0024 17.5 0.6 3.0 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 ETS82936.1 - 5.5e-06 26.4 6.1 0.0081 16.5 0.4 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 ETS82936.1 - 4.5e-05 23.7 4.9 0.008 16.4 0.4 3.8 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ETS82936.1 - 9.1e-05 23.0 1.2 0.1 13.5 0.1 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 ETS82936.1 - 0.0011 18.8 1.0 0.044 13.8 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 ETS82936.1 - 0.0022 18.5 0.1 0.014 16.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ETS82936.1 - 0.036 14.1 0.1 0.11 12.6 0.1 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat zf-NOSIP PF15906.5 ETS82936.1 - 0.039 14.1 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein UPF0564 PF10595.9 ETS82936.1 - 0.056 12.5 4.2 0.07 12.2 4.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 zf-Nse PF11789.8 ETS82936.1 - 0.058 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TPR_6 PF13174.6 ETS82936.1 - 0.25 12.1 2.8 0.48 11.2 0.3 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat Transferase PF02458.15 ETS82937.1 - 5.5e-16 58.3 0.0 7.4e-14 51.2 0.0 2.5 2 1 0 2 2 2 2 Transferase family Lipoxygenase PF00305.19 ETS82938.1 - 2.6e-28 98.9 0.1 3.7e-28 98.4 0.1 1.2 1 0 0 1 1 1 1 Lipoxygenase Pkinase PF00069.25 ETS82939.1 - 2.7e-09 36.8 0.0 1.1e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 ETS82939.1 - 0.00033 20.7 3.0 0.036 14.0 0.5 3.1 1 1 2 3 3 3 2 Phosphotransferase enzyme family GDP_Man_Dehyd PF16363.5 ETS82939.1 - 0.22 10.9 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HTH_Tnp_Tc5 PF03221.16 ETS82942.1 - 3.9e-21 74.9 5.7 6.2e-05 22.9 0.0 5.9 5 1 0 5 5 5 4 Tc5 transposase DNA-binding domain Homeobox_KN PF05920.11 ETS82942.1 - 6e-15 54.9 0.4 6e-15 54.9 0.4 3.0 4 0 0 4 4 4 1 Homeobox KN domain Homeodomain PF00046.29 ETS82942.1 - 3e-05 23.8 0.3 0.00011 22.0 0.3 1.9 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 ETS82942.1 - 0.0033 18.1 3.8 0.0033 18.1 3.8 5.0 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.26 ETS82942.1 - 0.0052 17.2 14.9 0.042 14.3 3.9 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ETS82942.1 - 0.55 10.6 2.1 2.3 8.6 2.1 2.2 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Elf1 PF05129.13 ETS82942.1 - 1.5 8.9 5.3 1.8 8.7 3.1 2.3 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like PAN_1 PF00024.26 ETS82943.1 - 0.01 15.8 0.1 0.027 14.4 0.0 1.6 1 1 0 1 1 1 0 PAN domain PAN_4 PF14295.6 ETS82943.1 - 0.091 12.7 2.7 6.9 6.7 2.7 2.7 1 1 0 1 1 1 0 PAN domain HEAT_2 PF13646.6 ETS82944.1 - 1.6e-27 95.7 19.0 2.1e-07 31.2 0.8 7.0 2 1 7 9 9 9 8 HEAT repeats HEAT PF02985.22 ETS82944.1 - 1.2e-11 43.8 6.5 0.65 10.4 0.0 10.2 10 0 0 10 10 10 1 HEAT repeat RTP1_C1 PF10363.9 ETS82944.1 - 6.2e-06 26.4 4.7 0.21 11.8 0.5 5.4 2 2 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 ETS82944.1 - 0.00028 21.0 9.0 0.8 9.7 1.0 5.8 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ETS82944.1 - 0.00076 18.2 9.3 0.23 10.0 1.9 4.4 3 2 0 3 3 3 2 Adaptin N terminal region Cohesin_HEAT PF12765.7 ETS82944.1 - 0.0014 18.9 15.3 1.7 9.0 0.1 6.5 7 0 0 7 7 7 2 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 ETS82944.1 - 0.0026 18.2 11.3 1.4 9.5 0.0 7.4 7 3 3 10 10 10 1 HEAT-like repeat CSN7a_helixI PF18392.1 ETS82944.1 - 0.0085 16.0 0.1 22 5.0 0.0 3.9 2 1 1 3 3 3 0 COP9 signalosome complex subunit 7a helix I domain DUF3549 PF12069.8 ETS82944.1 - 0.012 14.7 6.1 0.045 12.8 0.2 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF3549) DUF507 PF04368.13 ETS82944.1 - 0.015 15.3 4.0 0.057 13.4 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF507) Arm PF00514.23 ETS82944.1 - 0.024 14.7 1.5 28 4.9 0.1 5.2 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.6 ETS82944.1 - 0.028 14.8 3.3 46 4.5 0.1 5.1 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RB_B PF01857.20 ETS82944.1 - 0.047 13.7 0.0 1 9.4 0.0 2.9 2 1 0 2 2 2 0 Retinoblastoma-associated protein B domain Kdo PF06293.14 ETS82944.1 - 0.21 10.9 2.3 0.38 10.1 2.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NACHT PF05729.12 ETS82945.1 - 7.3e-15 55.3 0.0 1.6e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NLRC4_HD2 PF17776.1 ETS82945.1 - 4.6e-08 33.7 0.5 1.3e-07 32.2 0.2 1.8 1 1 0 1 1 1 1 NLRC4 helical domain HD2 NB-ARC PF00931.22 ETS82945.1 - 0.0001 21.6 0.0 0.00028 20.2 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 ETS82945.1 - 0.00031 21.2 0.0 0.0011 19.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS82945.1 - 0.0019 18.5 0.0 0.0045 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Abhydrolase_6 PF12697.7 ETS82945.1 - 0.0031 18.1 0.0 0.0059 17.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family NTPase_1 PF03266.15 ETS82945.1 - 0.027 14.4 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 ETS82945.1 - 0.033 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 ETS82945.1 - 0.04 14.3 0.0 0.093 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 ETS82945.1 - 0.061 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 ETS82945.1 - 0.073 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF3475 PF11961.8 ETS82945.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3475) AAA_24 PF13479.6 ETS82945.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Lactamase_B PF00753.27 ETS82946.1 - 4e-11 43.3 1.0 8.9e-11 42.2 1.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS82946.1 - 0.00056 19.5 0.2 0.0014 18.1 0.0 1.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Methyltransf_25 PF13649.6 ETS82947.1 - 1.4e-11 44.9 0.0 1.6e-10 41.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS82947.1 - 1.7e-10 40.6 0.0 2.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 ETS82947.1 - 7.5e-09 36.1 0.0 1.4e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS82947.1 - 4.3e-08 33.1 0.0 6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS82947.1 - 1.5e-06 28.1 0.0 2.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS82947.1 - 1.5e-05 25.6 0.0 2.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Nucleoporin_N PF08801.11 ETS82949.1 - 3.5e-96 322.6 0.1 5.1e-96 322.1 0.1 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 ETS82949.1 - 7.9e-48 163.6 6.0 1.2e-47 163.0 6.0 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal BAR_3 PF16746.5 ETS82949.1 - 0.095 12.4 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 BAR domain of APPL family DUF1824 PF08854.10 ETS82949.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) adh_short PF00106.25 ETS82950.1 - 5.3e-40 137.0 0.0 7.1e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS82950.1 - 3.2e-22 79.2 0.0 4.4e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS82950.1 - 9.8e-06 25.6 0.1 1.6e-05 24.9 0.1 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS82950.1 - 0.002 17.4 0.0 0.0027 16.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ETS82950.1 - 0.044 13.7 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ETS82950.1 - 0.052 13.8 0.1 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ETS82950.1 - 0.12 12.4 0.4 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Erg28 PF03694.13 ETS82951.1 - 2.8e-41 140.3 0.7 3.9e-41 139.9 0.7 1.2 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.22 ETS82952.1 - 2.2e-68 230.3 0.0 3.3e-67 226.5 0.0 2.1 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 ETS82952.1 - 2.6e-59 199.7 0.1 5e-59 198.8 0.1 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 ETS82952.1 - 5.5e-05 23.8 0.0 0.00046 20.9 0.0 2.2 2 1 0 2 2 2 1 HIT domain DcpS_C PF11969.8 ETS82952.1 - 0.04 14.4 0.1 0.73 10.3 0.0 2.3 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding DUF2025 PF09634.10 ETS82952.1 - 0.19 11.8 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2025) DUF4921 PF16268.5 ETS82952.1 - 0.23 10.2 0.9 10 4.8 0.0 3.1 2 2 2 4 4 4 0 Domain of unknown function (DUF4921) ZZ PF00569.17 ETS82954.1 - 1.6e-09 37.4 6.0 2.6e-09 36.7 4.3 2.1 2 0 0 2 2 2 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 ETS82954.1 - 3.3e-09 36.8 0.0 9.3e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 ETS82954.1 - 2.1e-06 27.9 0.0 8.5e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 ETS82954.1 - 9.7e-05 22.5 0.0 0.00029 21.0 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain O-FucT PF10250.9 ETS82955.1 - 4.6e-25 89.0 0.0 1.1e-24 87.8 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Rhodanese PF00581.20 ETS82956.1 - 3.6e-13 50.0 0.0 4.7e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain MDM10 PF12519.8 ETS82956.1 - 0.054 12.4 0.0 0.066 12.1 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 NUC153 PF08159.12 ETS82960.1 - 2e-12 46.7 1.2 2e-12 46.7 1.2 4.1 4 0 0 4 4 4 2 NUC153 domain Josephin PF02099.17 ETS82960.1 - 0.19 11.8 0.7 1.1 9.3 0.7 2.3 1 0 0 1 1 1 0 Josephin P5-ATPase PF12409.8 ETS82960.1 - 1.7 8.8 4.2 0.77 9.9 0.1 2.7 2 1 0 2 2 2 0 P5-type ATPase cation transporter PLDc_2 PF13091.6 ETS82961.1 - 1.1e-18 67.4 0.0 5.9e-07 29.4 0.0 3.6 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 ETS82961.1 - 6e-12 45.2 1.6 9e-05 22.5 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif F_bP_aldolase PF01116.20 ETS82961.1 - 0.034 13.6 0.1 0.054 13.0 0.1 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II Ribonuclease_T2 PF00445.18 ETS82962.1 - 4.7e-32 111.7 0.0 6.4e-30 104.7 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease T2 family Sec62 PF03839.16 ETS82963.1 - 5.2e-73 245.1 2.0 5.2e-73 245.1 2.0 1.4 2 0 0 2 2 2 1 Translocation protein Sec62 MatE PF01554.18 ETS82965.1 - 1.6e-54 183.9 30.1 4.6e-31 107.7 9.6 2.3 2 0 0 2 2 2 2 MatE DUF202 PF02656.15 ETS82966.1 - 2e-16 60.1 2.4 2e-15 57.0 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.12 ETS82966.1 - 0.013 15.6 0.0 0.013 15.6 0.0 2.1 2 1 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV GWT1 PF06423.12 ETS82966.1 - 0.029 14.5 2.0 0.032 14.3 1.2 1.5 1 1 0 1 1 1 0 GWT1 Tetraspanin PF00335.20 ETS82966.1 - 0.91 9.2 7.3 1 9.0 2.8 2.2 2 1 0 2 2 2 0 Tetraspanin family RTP1_C1 PF10363.9 ETS82968.1 - 0.037 14.2 2.1 0.76 10.0 1.0 3.3 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 ETS82968.1 - 0.069 13.4 1.9 1 9.8 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat DNA_pol_phi PF04931.13 ETS82968.1 - 2.6 6.0 14.1 1.3 7.1 10.9 2.0 2 0 0 2 2 2 0 DNA polymerase phi RRN3 PF05327.11 ETS82968.1 - 3.4 6.1 6.7 1.8 7.0 4.1 1.7 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 NUDIX PF00293.28 ETS82969.1 - 3.1e-27 95.2 0.0 5.3e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_7 PF13508.7 ETS82970.1 - 4.5e-07 30.2 0.1 1.4e-06 28.6 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS82970.1 - 4.5e-06 26.9 0.1 7.4e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ETS82970.1 - 3e-05 24.1 0.1 6.2e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS82970.1 - 7.9e-05 22.6 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS82970.1 - 0.0043 17.0 0.0 0.0085 16.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein RPA_C PF08784.11 ETS82971.1 - 1.1e-15 58.2 0.7 1.1e-15 58.2 0.7 1.9 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 ETS82971.1 - 3.3e-08 33.4 0.0 6.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 ETS82971.1 - 0.0081 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 Lon_C PF05362.13 ETS82972.1 - 1.2e-63 214.4 0.1 2.3e-63 213.4 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 ETS82972.1 - 1.3e-27 97.0 0.0 3.1e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 ETS82972.1 - 9.7e-23 81.0 0.0 2.6e-22 79.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 ETS82972.1 - 2.3e-08 33.9 0.1 1.3e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 ETS82972.1 - 9.4e-08 32.2 0.0 2.6e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ETS82972.1 - 4.1e-06 27.3 0.0 2e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 ETS82972.1 - 2.6e-05 24.0 0.0 0.00013 21.8 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 ETS82972.1 - 9.7e-05 21.7 0.1 0.00021 20.6 0.1 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 ETS82972.1 - 0.00014 22.2 0.0 0.0093 16.2 0.0 2.9 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.11 ETS82972.1 - 0.00047 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 ETS82972.1 - 0.0035 17.1 0.0 0.0085 15.8 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Rad17 PF03215.15 ETS82972.1 - 0.0041 17.1 0.0 0.0094 15.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_2 PF07724.14 ETS82972.1 - 0.01 15.9 0.0 0.05 13.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_23 PF13476.6 ETS82972.1 - 0.011 16.2 0.1 0.011 16.2 0.1 2.6 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ETS82972.1 - 0.013 15.7 0.1 0.036 14.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 ETS82972.1 - 0.013 14.9 0.3 0.057 12.8 0.1 2.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 ETS82972.1 - 0.018 15.4 0.0 0.039 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ETS82972.1 - 0.025 14.3 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ETS82972.1 - 0.025 14.1 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ETS82972.1 - 0.032 14.6 0.0 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 ETS82972.1 - 0.035 14.0 0.1 0.42 10.5 0.0 2.6 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.6 ETS82972.1 - 0.042 14.4 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain SOAR PF16533.5 ETS82972.1 - 0.044 13.8 0.6 0.12 12.4 0.6 1.7 1 0 0 1 1 1 0 STIM1 Orai1-activating region PhoH PF02562.16 ETS82972.1 - 0.044 13.2 0.0 0.099 12.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_PrkA PF08298.11 ETS82972.1 - 0.074 12.0 0.1 0.95 8.3 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain TsaE PF02367.17 ETS82972.1 - 0.075 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 ETS82972.1 - 0.093 12.4 0.1 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ETS82972.1 - 0.11 13.0 1.1 2 8.9 0.0 3.1 3 1 0 3 3 2 0 ABC transporter Parvo_NS1 PF01057.17 ETS82972.1 - 0.18 10.9 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 ETS82972.1 - 0.34 10.6 5.3 0.19 11.5 0.2 2.3 1 1 1 2 2 2 0 AAA domain Zn_clus PF00172.18 ETS82973.1 - 9.8e-07 28.8 10.9 1.5e-06 28.2 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_4 PF08448.10 ETS82973.1 - 0.032 14.5 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_9 PF13426.7 ETS82973.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 PAS domain Mlh1_C PF16413.5 ETS82975.1 - 1.6e-100 336.0 0.0 3.6e-100 334.8 0.0 1.6 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 ETS82975.1 - 2.4e-33 114.3 0.3 4e-33 113.6 0.3 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 ETS82975.1 - 3.4e-13 49.6 0.0 1e-12 48.0 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ETS82975.1 - 1.1e-06 29.1 0.0 3.1e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DnaJ PF00226.31 ETS82976.1 - 9e-14 51.4 0.4 9e-14 51.4 0.4 2.3 3 0 0 3 3 3 1 DnaJ domain DEAD PF00270.29 ETS82977.1 - 9.5e-50 168.8 0.0 4.5e-49 166.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS82977.1 - 5.3e-24 84.7 0.0 1.7e-23 83.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 ETS82977.1 - 1.8e-22 79.3 2.5 6.4e-22 77.6 2.5 2.0 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 ETS82977.1 - 1.1e-07 32.0 0.0 2.7e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ETS82977.1 - 0.011 14.9 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Fungal_trans PF04082.18 ETS82978.1 - 9.1e-10 38.0 0.3 3e-08 33.0 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Raptor_N PF14538.6 ETS82979.1 - 0.091 12.7 0.0 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain PAN_4 PF14295.6 ETS82981.1 - 0.0009 19.1 0.7 0.0039 17.1 0.7 2.1 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 ETS82981.1 - 0.058 13.5 1.3 0.19 11.9 1.3 1.8 1 0 0 1 1 1 0 PAN-like domain PAN_1 PF00024.26 ETS82981.1 - 0.19 11.7 2.6 0.37 10.8 0.1 2.5 3 0 0 3 3 3 0 PAN domain ADH_zinc_N PF00107.26 ETS82982.1 - 4.9e-27 94.5 0.0 8.6e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS82982.1 - 9.8e-20 72.0 0.1 2e-19 70.9 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS82982.1 - 4.9e-09 36.0 0.0 1.7e-07 31.1 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ETS82982.1 - 1e-05 25.4 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase NAD_binding_10 PF13460.6 ETS82982.1 - 0.0038 17.1 0.2 0.0081 16.1 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 ETS82982.1 - 0.021 14.3 0.5 0.033 13.7 0.5 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Peptidase_M13_N PF05649.13 ETS82982.1 - 0.034 13.8 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M13 Aldo_ket_red PF00248.21 ETS82983.1 - 1.5e-69 234.4 0.0 1.9e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 ETS82984.1 - 1e-27 96.9 0.0 1.5e-26 93.1 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS82984.1 - 4.2e-18 65.8 0.0 1.6e-17 63.8 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS82984.1 - 2.5e-05 24.3 0.8 0.00012 22.0 0.8 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS82984.1 - 0.018 14.5 0.0 5.4 6.4 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS82985.1 - 1.5e-22 80.4 0.1 1.9e-22 80.1 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS82985.1 - 0.0021 17.6 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ETS82985.1 - 0.0044 16.5 0.0 0.012 15.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ETS82985.1 - 0.02 14.0 0.1 0.034 13.3 0.1 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ETS82985.1 - 0.04 13.3 0.0 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 ETS82986.1 - 2.3e-51 174.1 0.0 2.9e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS82986.1 - 2.9e-39 135.0 0.0 3.9e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS82986.1 - 3.1e-08 33.7 0.0 4.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ETS82986.1 - 0.00092 19.1 0.0 0.0016 18.4 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS82986.1 - 0.0011 18.5 0.0 0.016 14.7 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ETS82986.1 - 0.0049 16.5 0.0 0.042 13.4 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family DUF1776 PF08643.10 ETS82986.1 - 0.0088 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Fungal_trans PF04082.18 ETS82987.1 - 8e-14 51.3 0.9 2.3e-13 49.8 0.5 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pyr_redox_2 PF07992.14 ETS82988.1 - 4e-11 42.7 0.0 1.5e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS82988.1 - 2.1e-09 37.0 0.0 1e-06 28.2 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ETS82988.1 - 4.7e-07 29.9 0.1 1.3e-05 25.2 0.1 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ETS82988.1 - 0.0056 16.0 1.3 1.3 8.2 0.0 3.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase CDO_I PF05995.12 ETS82989.1 - 7.4e-37 126.3 0.0 9.1e-37 126.0 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 ETS82989.1 - 0.0012 18.3 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 PCO_ADO PQQ_3 PF13570.6 ETS82990.1 - 0.0078 16.7 2.2 17 6.0 0.0 4.3 4 0 0 4 4 4 2 PQQ-like domain Fungal_trans_2 PF11951.8 ETS82991.1 - 5e-10 38.7 0.4 9.7e-10 37.8 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1156 PF06634.12 ETS82991.1 - 0.13 12.4 0.7 0.38 10.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1156) 4HB_MCP_1 PF12729.7 ETS82993.1 - 0.08 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Terpene_synth_C PF03936.16 ETS82994.1 - 2.4e-05 23.8 0.0 4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain adh_short PF00106.25 ETS82996.1 - 4.4e-15 55.7 0.0 4.3e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS82996.1 - 1.9e-09 37.4 0.0 1.7e-06 27.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS82996.1 - 5.5e-06 26.4 0.3 1.6e-05 24.9 0.1 1.8 2 0 0 2 2 2 1 KR domain DUF5305 PF17231.2 ETS82997.1 - 0.29 10.5 0.2 0.41 10.0 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Phage_Coat_B PF05356.11 ETS82997.1 - 0.46 10.4 4.1 0.75 9.7 3.6 1.6 1 1 0 1 1 1 0 Phage Coat protein B Aldo_ket_red PF00248.21 ETS82998.1 - 1.2e-35 123.2 0.0 1.3e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HET PF06985.11 ETS82999.1 - 1.8e-25 90.0 0.2 3e-25 89.3 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_3 PF07859.13 ETS83001.1 - 1.9e-31 109.6 0.0 2.6e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS83001.1 - 9.2e-12 44.5 0.0 3.3e-11 42.7 0.0 1.9 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 ETS83001.1 - 0.025 14.0 0.0 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Pyr_redox_2 PF07992.14 ETS83002.1 - 6e-14 52.0 0.0 1e-09 38.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS83002.1 - 7.8e-13 48.3 0.0 1.6e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS83002.1 - 4e-10 39.8 0.1 5.5e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 ETS83002.1 - 6.4e-08 31.5 0.0 1.5e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ETS83002.1 - 2e-07 30.5 0.0 0.00047 19.4 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 ETS83002.1 - 5.1e-05 22.6 0.2 0.00038 19.8 0.0 2.2 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 ETS83002.1 - 0.00023 20.9 0.6 0.0046 16.6 0.0 2.9 2 1 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ETS83002.1 - 0.00031 19.9 0.1 0.016 14.2 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 ETS83002.1 - 0.00047 20.2 0.1 2.1 8.3 0.0 4.0 3 1 1 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 ETS83002.1 - 0.0025 18.4 0.2 0.25 11.9 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS83002.1 - 0.028 13.5 0.2 4.7 6.2 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 ETS83002.1 - 0.057 12.7 0.0 2.8 7.1 0.0 2.9 3 1 1 4 4 4 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 ETS83002.1 - 0.44 9.2 1.7 1.1 7.9 0.0 2.4 4 0 0 4 4 4 0 HI0933-like protein HET PF06985.11 ETS83004.1 - 0.16 12.4 1.8 4.8 7.5 0.3 2.6 1 1 0 2 2 2 0 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.6 ETS83005.1 - 2.2e-14 53.5 26.1 1e-08 35.3 1.8 7.5 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 ETS83005.1 - 1.1e-09 38.3 15.6 0.019 15.8 0.0 7.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 ETS83005.1 - 1.8e-09 37.0 19.5 0.0067 16.5 0.1 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS83005.1 - 5.1e-08 33.3 15.0 0.00046 20.6 1.2 4.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 ETS83005.1 - 4.2e-07 29.6 14.8 0.15 12.0 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 ETS83005.1 - 1.3e-06 28.7 5.3 0.05 14.3 0.3 4.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ETS83005.1 - 2.1e-06 28.3 17.9 0.0016 19.0 1.6 5.1 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 ETS83005.1 - 2.3e-06 27.2 13.5 0.096 12.8 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 ETS83005.1 - 2.1e-05 24.7 10.7 0.67 10.8 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat BTAD PF03704.17 ETS83005.1 - 3.9e-05 24.1 3.9 0.022 15.2 0.5 3.4 2 1 1 3 3 3 2 Bacterial transcriptional activator domain ANAPC3 PF12895.7 ETS83005.1 - 0.0002 21.5 17.1 0.049 13.9 0.9 5.9 5 2 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 ETS83005.1 - 0.00025 21.0 1.2 0.18 11.9 0.2 2.9 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 ETS83005.1 - 0.00037 20.8 4.4 0.0081 16.5 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 ETS83005.1 - 0.0013 18.9 3.3 0.037 14.2 0.9 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ETS83005.1 - 0.0048 16.7 15.6 0.057 13.3 0.3 6.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS83005.1 - 0.034 13.5 9.9 0.0096 15.3 1.5 3.0 1 1 2 3 3 3 0 MalT-like TPR region TPR_11 PF13414.6 ETS83005.1 - 0.037 13.7 9.7 3.1 7.6 0.3 4.8 5 1 0 5 5 5 0 TPR repeat YfiO PF13525.6 ETS83005.1 - 0.087 12.5 1.9 4.2 7.0 0.1 2.5 2 0 0 2 2 2 0 Outer membrane lipoprotein TPR_8 PF13181.6 ETS83005.1 - 0.16 12.3 13.8 0.83 10.0 0.8 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 ETS83006.1 - 8.2e-18 64.4 41.9 6.4e-17 61.5 37.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS83006.1 - 8.1e-05 21.7 26.3 0.017 14.0 25.7 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter PTR2 PF00854.21 ETS83006.1 - 0.019 13.8 0.1 0.019 13.8 0.1 2.7 2 1 0 2 2 2 0 POT family Pribosyltran_N PF13793.6 ETS83007.1 - 2.2e-40 137.2 0.0 5.9e-40 135.8 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 ETS83007.1 - 4.8e-35 121.3 0.1 5e-29 101.6 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 ETS83007.1 - 4.2e-09 36.1 0.0 2.4e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain UPRTase PF14681.6 ETS83007.1 - 0.078 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase XPG_I_2 PF12813.7 ETS83008.1 - 1.2e-37 129.8 0.0 2e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.17 ETS83008.1 - 0.03 14.8 0.0 0.077 13.5 0.0 1.8 1 0 0 1 1 1 0 XPG N-terminal domain Anoctamin PF04547.12 ETS83009.1 - 9.7e-116 387.2 7.2 1.2e-115 387.0 7.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Metallophos PF00149.28 ETS83010.1 - 6.3e-10 39.9 1.5 1.1e-09 39.0 1.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WSC PF01822.19 ETS83011.1 - 1.8e-10 40.9 10.5 1.8e-10 40.9 10.5 2.6 3 0 0 3 3 3 1 WSC domain Pkinase PF00069.25 ETS83012.1 - 8.5e-16 58.1 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS83012.1 - 2.5e-10 40.1 0.0 2.9e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ETS83012.1 - 0.0096 15.3 0.2 0.013 14.8 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Aconitase PF00330.20 ETS83013.1 - 1.7e-106 357.0 0.7 1.4e-105 354.0 0.7 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ETS83013.1 - 2.3e-25 89.4 0.0 9.4e-25 87.5 0.0 2.1 2 0 0 2 2 2 1 Aconitase C-terminal domain DUF5526 PF17664.1 ETS83013.1 - 0.5 9.9 3.1 1.6 8.3 1.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5526) Carn_acyltransf PF00755.20 ETS83014.1 - 3.4e-199 663.3 0.0 3.9e-199 663.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CAP_N PF01213.19 ETS83015.1 - 6.6e-115 383.9 0.5 1.3e-114 383.0 0.5 1.5 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 ETS83015.1 - 1.3e-56 190.5 0.3 1.8e-56 190.1 0.3 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal PfkB PF00294.24 ETS83016.1 - 1.1e-14 54.5 0.0 1.8e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 ETS83016.1 - 0.088 12.2 0.0 1.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase GFO_IDH_MocA PF01408.22 ETS83017.1 - 3.1e-16 60.3 0.0 5.5e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 ETS83017.1 - 0.032 14.9 0.0 0.061 14.0 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain BCA_ABC_TP_C PF12399.8 ETS83017.1 - 1 9.4 3.1 0.4 10.6 0.2 1.9 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter Ank_4 PF13637.6 ETS83018.1 - 3.3e-47 158.3 13.4 4.6e-10 39.8 0.1 4.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS83018.1 - 3e-46 155.9 17.8 1.8e-15 57.3 1.4 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS83018.1 - 1.1e-33 111.4 4.7 2.2e-05 24.5 0.1 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 ETS83018.1 - 3e-29 100.1 13.9 1.8e-06 28.1 0.1 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 ETS83018.1 - 9.7e-20 70.4 12.9 0.00045 20.4 0.2 6.0 2 2 4 6 6 6 6 Ankyrin repeats (many copies) OCD_Mu_crystall PF02423.15 ETS83018.1 - 0.024 13.6 0.2 3.2 6.6 0.0 2.9 1 1 2 3 3 3 0 Ornithine cyclodeaminase/mu-crystallin family FA PF08736.11 ETS83018.1 - 0.11 12.6 0.0 6.1 7.0 0.0 2.5 2 0 0 2 2 2 0 FERM adjacent (FA) MMS1_N PF10433.9 ETS83019.1 - 9.5e-117 390.6 0.2 1.6e-116 389.8 0.2 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 ETS83019.1 - 1.6e-66 224.8 0.0 3.2e-66 223.9 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region Fungal_trans_2 PF11951.8 ETS83020.1 - 1.2e-07 30.9 0.0 2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rieske PF00355.26 ETS83022.1 - 3.2e-11 43.0 0.0 5.6e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 ETS83022.1 - 1.7e-09 38.0 0.8 6.3e-09 36.2 0.8 2.0 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region ABM PF03992.16 ETS83023.1 - 0.035 14.2 0.1 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase LapA_dom PF06305.11 ETS83024.1 - 0.1 12.4 3.1 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain EF-hand_1 PF00036.32 ETS83025.1 - 3.2e-34 113.9 12.1 1.7e-08 33.4 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ETS83025.1 - 1e-30 106.0 6.6 1.1e-15 57.8 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ETS83025.1 - 1.1e-28 96.6 7.8 4.1e-09 35.6 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 ETS83025.1 - 3.2e-24 84.5 8.6 4.5e-10 39.2 0.5 3.4 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 ETS83025.1 - 1.2e-18 65.7 13.8 3.2e-06 26.4 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 ETS83025.1 - 2.9e-16 59.6 0.5 2e-08 34.4 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 ETS83025.1 - 2.9e-09 36.8 3.3 0.0008 19.3 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 ETS83025.1 - 4.7e-08 33.3 0.3 0.00058 20.2 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 ETS83025.1 - 7.2e-07 29.5 0.3 0.02 15.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 ETS83025.1 - 1e-06 29.6 0.1 0.0016 19.3 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain SurA_N_2 PF13623.6 ETS83025.1 - 0.00069 19.5 0.6 0.16 11.9 0.1 2.4 2 0 0 2 2 2 1 SurA N-terminal domain Toprim_2 PF13155.6 ETS83025.1 - 0.0018 18.7 0.7 0.65 10.5 0.1 2.4 1 1 1 2 2 2 1 Toprim-like SurA_N_3 PF13624.6 ETS83025.1 - 0.0023 17.7 0.4 0.14 11.9 0.0 2.1 1 1 0 2 2 2 1 SurA N-terminal domain Caleosin PF05042.13 ETS83025.1 - 0.008 16.1 0.2 11 5.9 0.0 3.3 1 1 3 4 4 4 0 Caleosin related protein TerB PF05099.13 ETS83025.1 - 0.011 15.7 0.2 1.1 9.3 0.0 2.3 1 1 0 2 2 2 0 Tellurite resistance protein TerB UPF0154 PF03672.13 ETS83025.1 - 0.012 15.7 0.0 2.7 8.1 0.0 2.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0154) DUF2267 PF10025.9 ETS83025.1 - 0.018 15.3 0.1 0.17 12.2 0.1 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) MotA_activ PF09114.10 ETS83025.1 - 0.035 14.2 0.0 3.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Transcription factor MotA, activation domain DUF5580 PF17743.1 ETS83025.1 - 0.04 12.5 0.0 3.5 6.0 0.0 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5580) DUF4497 PF14924.6 ETS83025.1 - 0.054 14.0 0.0 0.25 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) Arc_PepC PF06819.11 ETS83025.1 - 0.056 13.6 1.6 0.82 9.8 0.1 2.4 1 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain AAA_assoc_C PF09821.9 ETS83025.1 - 0.099 13.2 0.4 1.4 9.4 0.1 2.6 1 1 1 3 3 3 0 C-terminal AAA-associated domain VbhA PF18495.1 ETS83025.1 - 0.24 11.3 1.4 25 4.8 0.2 3.8 4 1 0 4 4 4 0 Antitoxin VbhA DED PF01335.21 ETS83025.1 - 0.27 11.6 1.3 6.9 7.1 0.1 2.4 2 0 0 2 2 2 0 Death effector domain Ribosomal_L11 PF00298.19 ETS83026.1 - 9.8e-28 96.5 0.6 1.6e-27 95.8 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 ETS83026.1 - 6.6e-26 89.9 0.1 1.2e-25 89.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Svf1_C PF17187.4 ETS83027.1 - 3.6e-61 205.8 0.1 7.7e-61 204.7 0.0 1.6 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 ETS83027.1 - 1.9e-53 180.9 0.0 2.7e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain KH_4 PF13083.6 ETS83027.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 KH domain CENP-T_C PF15511.6 ETS83028.1 - 0.00026 21.1 0.0 0.00031 20.8 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 ETS83028.1 - 0.055 13.6 0.0 0.066 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Acetyltransf_1 PF00583.25 ETS83029.1 - 6.4e-06 26.4 0.1 1.1e-05 25.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pho86 PF11124.8 ETS83029.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 DUF4473 PF14747.6 ETS83030.1 - 0.096 13.3 0.1 0.32 11.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) FAR1 PF03101.15 ETS83031.1 - 0.005 17.5 0.0 0.005 17.5 0.0 2.6 2 0 0 2 2 2 1 FAR1 DNA-binding domain AAA_23 PF13476.6 ETS83031.1 - 4.9 7.6 13.7 1.5 9.3 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 ETS83032.1 - 1.9e-121 405.0 4.7 2.5e-121 404.7 0.0 3.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 ETS83032.1 - 2.7e-120 402.7 8.5 2.7e-120 402.7 8.5 4.1 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 ETS83032.1 - 2.6e-106 356.1 9.0 2.6e-106 356.1 9.0 5.4 5 2 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 ETS83032.1 - 1.5e-74 249.8 0.1 1.5e-74 249.8 0.1 3.0 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_8 PF12780.7 ETS83032.1 - 7.2e-66 222.2 0.0 1.1e-64 218.3 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.7 ETS83032.1 - 4.9e-47 160.6 9.5 5.7e-46 157.1 9.0 2.4 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 ETS83032.1 - 1.1e-43 148.9 0.0 1.3e-37 129.1 0.0 4.9 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 ETS83032.1 - 1.1e-33 116.4 0.0 3.8e-33 114.6 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 ETS83032.1 - 9.7e-32 109.8 0.0 8.2e-12 45.3 0.0 6.6 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 ETS83032.1 - 2.3e-30 105.1 0.0 2.7e-27 95.2 0.0 4.0 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 ETS83032.1 - 1.3e-15 57.6 0.5 6.3e-15 55.4 0.0 2.5 3 0 0 3 3 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 ETS83032.1 - 3.3e-13 50.2 0.0 0.0026 18.2 0.0 4.7 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS83032.1 - 1.1e-12 48.4 2.2 0.03 14.6 0.0 6.5 7 0 0 7 7 5 3 AAA domain AAA_18 PF13238.6 ETS83032.1 - 2.3e-10 41.1 0.2 0.048 14.2 0.0 5.7 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 ETS83032.1 - 4.4e-10 40.2 0.6 1 9.7 0.0 6.7 7 0 0 7 7 5 2 AAA ATPase domain AAA_33 PF13671.6 ETS83032.1 - 9.9e-10 38.7 0.3 0.15 12.3 0.0 5.2 4 0 0 4 4 4 3 AAA domain T2SSE PF00437.20 ETS83032.1 - 2.5e-05 23.5 0.0 0.046 12.8 0.0 3.6 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_29 PF13555.6 ETS83032.1 - 3.4e-05 23.5 0.0 1.7 8.4 0.0 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.21 ETS83032.1 - 4.7e-05 22.9 0.4 0.54 9.6 0.0 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_lid_1 PF17857.1 ETS83032.1 - 6e-05 23.2 0.0 0.00037 20.7 0.0 2.4 1 0 0 1 1 1 1 AAA+ lid domain ABC_tran PF00005.27 ETS83032.1 - 0.00011 22.7 0.0 5.9 7.4 0.0 4.7 3 0 0 3 3 3 0 ABC transporter FtsK_SpoIIIE PF01580.18 ETS83032.1 - 0.00014 21.3 0.0 1.8 7.9 0.0 3.7 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_30 PF13604.6 ETS83032.1 - 0.00038 20.2 0.5 45 3.7 0.0 5.2 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.6 ETS83032.1 - 0.00071 19.9 0.2 0.51 10.7 0.0 4.1 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.6 ETS83032.1 - 0.0061 16.2 0.1 0.64 9.6 0.0 3.3 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 ETS83032.1 - 0.0066 16.2 1.4 0.94 9.2 0.0 4.3 5 0 0 5 5 4 1 IstB-like ATP binding protein RNA_helicase PF00910.22 ETS83032.1 - 0.016 15.6 0.0 48 4.4 0.0 4.5 4 0 0 4 4 4 0 RNA helicase Rad17 PF03215.15 ETS83032.1 - 0.016 15.1 0.1 8.8 6.2 0.0 3.6 3 0 0 3 3 3 0 Rad17 P-loop domain Zeta_toxin PF06414.12 ETS83032.1 - 0.016 14.5 0.2 27 4.0 0.0 4.7 4 0 0 4 4 4 0 Zeta toxin AAA_24 PF13479.6 ETS83032.1 - 0.023 14.4 3.4 38 3.9 0.0 4.7 6 0 0 6 6 5 0 AAA domain RuvB_N PF05496.12 ETS83032.1 - 0.05 13.4 0.1 3 7.5 0.0 3.2 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 ETS83032.1 - 0.076 12.9 3.4 32 4.4 0.0 4.4 4 0 0 4 4 3 0 NACHT domain Fibin PF15819.5 ETS83032.1 - 0.11 12.3 1.2 0.62 9.8 1.2 2.4 1 0 0 1 1 1 0 Fin bud initiation factor homologue DUF5304 PF17230.2 ETS83032.1 - 0.12 12.6 3.5 0.49 10.6 0.6 3.4 3 0 0 3 3 2 0 Family of unknown function (DUF5304) NTPase_1 PF03266.15 ETS83032.1 - 0.98 9.3 4.2 35 4.2 0.0 4.4 5 0 0 5 5 5 0 NTPase Rad60-SLD PF11976.8 ETS83033.1 - 1.7e-11 43.8 0.1 3.1e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ETS83033.1 - 0.00067 19.4 0.0 0.001 18.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin family SH3_1 PF00018.28 ETS83033.1 - 0.16 11.6 0.4 0.31 10.7 0.4 1.4 1 0 0 1 1 1 0 SH3 domain PEX11 PF05648.14 ETS83034.1 - 0.067 12.6 4.1 18 4.7 0.0 3.3 3 1 0 3 3 3 0 Peroxisomal biogenesis factor 11 (PEX11) CTU2 PF10288.9 ETS83036.1 - 1.7e-12 47.6 0.0 2.4e-10 40.6 0.0 2.7 1 1 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 Mito_carr PF00153.27 ETS83037.1 - 1.1e-56 188.8 2.7 3.9e-19 68.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MotA_ExbB PF01618.16 ETS83037.1 - 0.063 13.0 0.0 0.2 11.4 0.0 1.9 1 1 0 1 1 1 0 MotA/TolQ/ExbB proton channel family FHA PF00498.26 ETS83038.1 - 3.6e-15 56.0 0.0 7.3e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 ETS83038.1 - 1.9e-13 49.9 5.6 3.5e-13 49.0 5.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 ETS83038.1 - 9.1e-07 29.1 9.8 1.5e-06 28.4 9.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ETS83038.1 - 0.0011 18.8 6.6 0.0018 18.2 6.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ETS83038.1 - 0.0014 18.5 9.4 0.0023 17.8 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 ETS83038.1 - 0.0052 17.1 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_2 PF13923.6 ETS83038.1 - 0.033 14.0 9.1 0.056 13.3 9.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS83038.1 - 0.079 13.0 8.9 0.16 12.0 8.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger lci PF12197.8 ETS83038.1 - 0.094 12.5 0.4 0.25 11.2 0.4 1.7 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein zf-C3HC4_3 PF13920.6 ETS83038.1 - 0.19 11.6 6.2 0.3 11.0 6.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 ETS83038.1 - 0.26 11.2 4.5 0.47 10.4 4.5 1.4 1 0 0 1 1 1 0 PHD-finger PPP4R2 PF09184.11 ETS83038.1 - 1.7 8.2 8.2 3.6 7.1 8.2 1.5 1 0 0 1 1 1 0 PPP4R2 zf-rbx1 PF12678.7 ETS83038.1 - 2.2 8.6 9.8 7.1 7.0 9.8 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING-like PF08746.11 ETS83038.1 - 3.2 8.1 5.4 6.5 7.2 5.4 1.5 1 0 0 1 1 1 0 RING-like domain Glyco_hydro_43 PF04616.14 ETS83039.1 - 6.1e-05 22.5 2.5 8.5e-05 22.0 2.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GBP PF02263.19 ETS83039.1 - 0.091 12.0 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Glyco_hydro_76 PF03663.14 ETS83040.1 - 7.5e-147 489.6 23.3 8.9e-147 489.4 23.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 ETS83040.1 - 0.0046 16.1 8.8 0.21 10.6 1.1 3.2 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 Lipase_GDSL PF00657.22 ETS83041.1 - 3.2e-09 37.1 0.0 3.9e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ETS83041.1 - 1.2e-08 35.6 1.0 1.6e-08 35.1 1.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF4125 PF13526.6 ETS83041.1 - 0.2 11.3 0.0 0.27 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4125) Abhydrolase_6 PF12697.7 ETS83042.1 - 0.00033 21.3 0.0 0.00039 21.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS83042.1 - 0.0031 16.8 0.0 0.014 14.7 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Cutinase PF01083.22 ETS83042.1 - 0.0056 16.7 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 Cutinase DUF676 PF05057.14 ETS83042.1 - 0.0067 16.0 0.0 0.011 15.2 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 ETS83042.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Rax2 PF12768.7 ETS83043.1 - 0.0034 16.9 0.0 0.0054 16.2 0.0 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity TMEM154 PF15102.6 ETS83043.1 - 0.19 11.6 4.5 0.77 9.7 4.5 1.9 1 1 0 1 1 1 0 TMEM154 protein family Alpha_GJ PF03229.13 ETS83043.1 - 1 9.9 14.2 2.8 8.5 13.9 2.0 1 1 0 1 1 1 0 Alphavirus glycoprotein J Mucin PF01456.17 ETS83043.1 - 2.4 8.2 26.4 4.6 7.2 26.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein TP_methylase PF00590.20 ETS83044.1 - 6.1e-25 88.4 0.1 1.1e-24 87.6 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.8 ETS83045.1 - 2.7e-09 37.1 0.3 5.2e-09 36.2 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ETS83045.1 - 2.4e-05 24.6 0.4 4.6e-05 23.7 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 ETS83045.1 - 0.00075 19.5 1.4 0.0021 18.1 1.4 1.8 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-DBF PF07535.12 ETS83045.1 - 0.001 19.2 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 DBF zinc finger LPP20 PF02169.16 ETS83045.1 - 0.38 11.1 2.8 0.45 10.9 0.5 2.1 2 1 0 2 2 2 0 LPP20 lipoprotein F-box-like PF12937.7 ETS83046.1 - 0.0048 16.8 0.5 0.024 14.5 0.5 2.2 1 1 0 1 1 1 1 F-box-like Pyrid_ox_like PF16242.5 ETS83047.1 - 3.2e-26 91.7 0.0 4.8e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 ETS83047.1 - 3.1e-10 40.1 0.0 8.2e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 ETS83047.1 - 0.012 15.4 0.0 0.24 11.1 0.0 2.1 1 1 1 2 2 2 0 Putative FMN-binding domain S1-P1_nuclease PF02265.16 ETS83050.1 - 3.8e-74 249.7 1.0 4.3e-74 249.5 1.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Sugar_tr PF00083.24 ETS83051.1 - 0.0086 15.0 3.9 0.0097 14.8 3.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Esterase PF00756.20 ETS83052.1 - 2.1e-07 30.8 0.2 9e-07 28.8 0.2 2.0 1 1 0 1 1 1 1 Putative esterase CBM_48 PF02922.18 ETS83052.1 - 0.013 15.8 0.1 7 7.1 0.0 2.6 2 0 0 2 2 2 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) AMPK1_CBM PF16561.5 ETS83052.1 - 0.025 14.8 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase Ank_2 PF12796.7 ETS83053.1 - 2.4e-07 31.3 0.0 7.1e-06 26.5 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS83053.1 - 0.00016 21.9 0.0 0.022 15.1 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS83053.1 - 0.00077 20.0 0.0 0.12 13.0 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS83053.1 - 0.0016 18.8 0.0 0.041 14.4 0.0 3.2 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 ETS83053.1 - 0.024 15.1 0.1 1.3 9.6 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 ETS83054.1 - 2.6e-21 76.0 1.0 3.4e-11 43.6 0.2 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS83054.1 - 2.2e-14 53.6 1.8 1.7e-07 31.6 0.0 5.0 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS83054.1 - 8.8e-13 48.2 1.3 1.4e-05 25.3 0.0 4.7 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS83054.1 - 1.7e-12 46.3 4.2 0.045 14.3 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 ETS83054.1 - 2.6e-10 40.3 1.4 0.071 13.6 0.0 5.1 6 0 0 6 6 6 3 Ankyrin repeat F-box-like PF12937.7 ETS83054.1 - 0.14 12.0 0.0 0.39 10.6 0.0 1.8 1 1 0 1 1 1 0 F-box-like Transp_cyt_pur PF02133.15 ETS83055.1 - 8.6e-25 87.4 39.7 1.3e-24 86.8 39.7 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cupin_1 PF00190.22 ETS83056.1 - 9.6e-36 122.7 0.0 1.2e-16 60.7 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 ETS83056.1 - 1.5e-22 79.1 0.3 1e-11 44.3 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 ETS83056.1 - 4.2e-07 29.5 0.0 0.011 15.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 ETS83056.1 - 7.7e-06 25.9 0.0 0.00015 21.7 0.0 2.5 3 0 0 3 3 3 1 AraC-like ligand binding domain DUF1971 PF09313.11 ETS83056.1 - 0.00089 19.2 0.0 0.028 14.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1971) 3-HAO PF06052.12 ETS83056.1 - 0.0013 18.4 0.0 0.0059 16.3 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase MannoseP_isomer PF01050.18 ETS83056.1 - 0.0021 18.0 0.0 0.0087 16.0 0.0 1.8 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Asp PF00026.23 ETS83057.1 - 3.7e-50 171.1 0.1 4.9e-50 170.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS83057.1 - 5.1e-06 26.9 0.2 1.3e-05 25.5 0.2 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ETS83057.1 - 0.0016 19.0 0.9 0.38 11.4 0.1 3.1 2 1 0 2 2 2 2 Aspartyl protease UQ_con PF00179.26 ETS83058.1 - 1e-37 128.9 0.0 1.2e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ETS83058.1 - 0.19 11.4 0.2 0.38 10.5 0.2 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B Glyco_trans_1_4 PF13692.6 ETS83059.1 - 2.1e-07 31.4 0.0 2.5e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 ETS83059.1 - 4.4e-05 23.1 0.0 0.00021 20.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ETS83059.1 - 0.071 13.5 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Cation_efflux PF01545.21 ETS83060.1 - 2e-47 161.5 8.1 2.8e-47 161.0 8.1 1.2 1 0 0 1 1 1 1 Cation efflux family SH3_3 PF08239.11 ETS83061.1 - 0.068 13.5 0.1 20 5.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain Mito_carr PF00153.27 ETS83062.1 - 8.1e-58 192.4 1.7 2.2e-19 69.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Taq-exonuc PF09281.10 ETS83062.1 - 0.076 13.0 0.0 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 Taq polymerase, exonuclease His_Phos_1 PF00300.22 ETS83063.1 - 5.2e-05 23.0 0.1 0.45 10.2 0.0 4.5 5 0 0 5 5 5 3 Histidine phosphatase superfamily (branch 1) Lipase_GDSL PF00657.22 ETS83064.1 - 8.7e-14 52.0 0.0 1.1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ETS83064.1 - 2.8e-10 40.9 0.5 3.9e-10 40.4 0.5 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Creatininase PF02633.14 ETS83064.1 - 0.067 12.7 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 Creatinine amidohydrolase Glyco_hydro2_C5 PF18565.1 ETS83065.1 - 1.8e-34 117.6 0.2 3.1e-34 116.9 0.2 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_C PF02836.17 ETS83065.1 - 1.1e-23 83.8 0.0 3.4e-23 82.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 ETS83065.1 - 7.6e-21 73.8 0.1 1.8e-20 72.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Glyco_hydro_2_N PF02837.18 ETS83065.1 - 8.1e-17 61.6 0.8 3.3e-16 59.7 0.3 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 ETS83065.1 - 7.8e-12 45.8 0.0 1.9e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Invasin_D3 PF09134.10 ETS83065.1 - 4.4e-06 26.9 3.5 4.4e-06 26.9 3.5 2.9 2 0 0 2 2 2 1 Invasin, domain 3 BetaGal_dom4_5 PF13364.6 ETS83065.1 - 0.00047 20.7 0.1 0.0024 18.4 0.0 2.3 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Big_1 PF02369.16 ETS83065.1 - 0.0032 17.4 1.2 0.0032 17.4 1.2 3.2 3 0 0 3 3 3 1 Bacterial Ig-like domain (group 1) DUF1908 PF08926.11 ETS83065.1 - 0.49 9.4 1.6 0.79 8.8 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Glyco_hydro_43 PF04616.14 ETS83066.1 - 2.1e-68 230.7 0.6 2.7e-68 230.4 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ETS83066.1 - 7e-24 84.7 0.0 1.3e-23 83.8 0.0 1.5 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_32N PF00251.20 ETS83066.1 - 0.0079 15.8 0.0 2.3 7.7 0.0 2.7 1 1 2 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain DnaJ PF00226.31 ETS83067.1 - 3.1e-08 33.6 1.2 6.2e-08 32.7 1.2 1.6 1 0 0 1 1 1 1 DnaJ domain Ferric_reduct PF01794.19 ETS83068.1 - 7.1e-09 35.8 6.9 1.4e-08 34.9 6.9 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ETS83068.1 - 1.2e-07 32.0 0.4 0.0024 18.0 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ETS83068.1 - 0.00024 21.2 0.6 0.0025 17.9 0.6 2.6 1 1 0 1 1 1 1 FAD-binding domain ABC_tran_2 PF16949.5 ETS83068.1 - 0.031 13.1 2.7 0.045 12.6 2.7 1.1 1 0 0 1 1 1 0 Putative ATP-binding cassette DUF420 PF04238.12 ETS83068.1 - 0.065 13.5 6.9 0.19 12.0 6.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF420) DUF872 PF05915.12 ETS83068.1 - 0.56 10.4 3.8 16 5.7 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) peroxidase PF00141.23 ETS83069.1 - 1.4e-29 103.5 0.0 2.2e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 ETS83069.1 - 0.049 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Fungal peroxidase extension region Goodbye PF17109.5 ETS83070.1 - 0.00014 22.3 0.2 0.0011 19.4 0.0 2.7 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain TPR_20 PF14561.6 ETS83070.1 - 0.0056 17.0 0.5 0.053 13.9 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat NACHT PF05729.12 ETS83070.1 - 0.022 14.7 0.0 0.37 10.7 0.0 3.0 2 0 0 2 2 2 0 NACHT domain TPR_2 PF07719.17 ETS83070.1 - 0.025 14.7 2.9 14 6.1 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 ETS83070.1 - 0.24 11.9 2.9 2.4 8.7 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 ETS83070.1 - 4.3 8.1 8.5 0.6 10.8 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat GMC_oxred_C PF05199.13 ETS83071.1 - 0.0064 17.0 0.0 0.0078 16.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Dynamin_N PF00350.23 ETS83072.1 - 2.1e-13 50.6 0.7 4.6e-13 49.6 0.7 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 ETS83072.1 - 1.3e-07 31.1 0.0 3.8e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Dynamin central region Roc PF08477.13 ETS83072.1 - 6.4e-05 23.2 0.1 0.019 15.2 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GED PF02212.18 ETS83072.1 - 0.00081 19.5 0.0 0.0046 17.1 0.0 2.4 1 0 0 1 1 1 1 Dynamin GTPase effector domain FeoB_N PF02421.18 ETS83072.1 - 0.0064 16.0 0.5 0.025 14.1 0.4 2.1 2 1 0 2 2 2 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 ETS83072.1 - 0.011 15.8 0.8 0.068 13.2 0.8 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 ETS83072.1 - 0.017 15.5 0.9 0.42 11.0 0.0 3.4 3 2 0 3 3 3 0 AAA ATPase domain AAA_15 PF13175.6 ETS83072.1 - 0.021 14.5 0.0 0.041 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF2087 PF09860.9 ETS83072.1 - 0.058 13.5 1.1 0.94 9.7 1.4 2.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) GAT PF03127.14 ETS83072.1 - 0.081 13.2 1.3 0.33 11.3 0.4 2.5 2 0 0 2 2 1 0 GAT domain Arf PF00025.21 ETS83072.1 - 0.11 11.9 0.1 9.6 5.6 0.1 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family Ras PF00071.22 ETS83072.1 - 0.12 11.9 0.1 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Ras family AAA_26 PF13500.6 ETS83072.1 - 0.13 12.1 0.1 0.75 9.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 ETS83072.1 - 0.13 12.1 0.2 0.56 10.1 0.2 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea SWC7 PF17330.2 ETS83072.1 - 0.2 11.7 1.1 3 8.0 0.1 3.2 3 0 0 3 3 3 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 AAA_23 PF13476.6 ETS83072.1 - 1.7 9.1 6.5 0.67 10.4 1.0 2.8 2 1 0 2 2 2 0 AAA domain Glyco_hydro_63 PF03200.16 ETS83073.1 - 6.2e-143 477.1 1.6 1.3e-141 472.8 0.2 2.7 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 ETS83073.1 - 2.6e-34 119.3 0.0 5.4e-34 118.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 ETS83073.1 - 1.2e-08 34.3 0.0 2.1e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 ETS83073.1 - 5.6e-05 22.1 0.0 9.9e-05 21.3 0.0 1.4 1 0 0 1 1 1 1 Trehalase MFS_1 PF07690.16 ETS83074.1 - 1.1e-31 110.1 28.5 4.5e-30 104.8 27.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS83074.1 - 0.0048 15.8 2.5 0.0048 15.8 2.5 1.8 2 0 0 2 2 2 1 MFS_1 like family OATP PF03137.20 ETS83074.1 - 0.0054 15.1 3.7 0.016 13.5 3.9 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Glycophorin_A PF01102.18 ETS83074.1 - 0.15 12.3 0.0 4.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Glycophorin A p450 PF00067.22 ETS83075.1 - 1.7e-19 70.0 0.1 4.6e-19 68.5 0.1 1.6 1 1 1 2 2 2 2 Cytochrome P450 COesterase PF00135.28 ETS83076.1 - 4.7e-87 293.0 0.0 6.1e-87 292.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS83076.1 - 6.5e-06 26.2 0.0 0.00072 19.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 ETS83077.1 - 0.0079 16.1 0.4 0.016 15.1 0.4 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS83077.1 - 0.04 13.4 0.1 0.064 12.7 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family APH PF01636.23 ETS83078.1 - 1.9e-20 73.8 0.0 2.5e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETS83078.1 - 0.0003 20.5 0.0 0.00042 20.0 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 ETS83078.1 - 0.00087 18.9 0.2 0.096 12.3 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Fructosamin_kin PF03881.14 ETS83078.1 - 0.0029 16.9 0.0 0.007 15.6 0.0 1.6 1 1 0 1 1 1 1 Fructosamine kinase DUF4746 PF15928.5 ETS83078.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) WD40 PF00400.32 ETS83080.1 - 3.3e-85 277.7 30.4 3.2e-09 37.2 0.1 18.6 18 0 0 18 18 17 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS83080.1 - 5.4e-48 161.2 1.9 0.00042 20.5 0.0 14.7 3 3 9 14 14 14 9 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS83080.1 - 1.5e-19 70.1 3.1 0.3 10.0 0.0 11.2 6 5 7 13 13 13 5 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 ETS83080.1 - 2.1e-17 63.5 0.0 4.4e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 ETS83080.1 - 1.3e-16 60.0 10.3 0.069 13.1 0.1 11.3 12 0 0 12 12 11 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 ETS83080.1 - 2.7e-11 43.7 0.0 0.036 13.9 0.0 6.3 4 2 3 7 7 7 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 ETS83080.1 - 4.7e-08 32.0 4.2 0.0056 15.3 0.1 5.6 4 1 2 6 6 6 1 Cytochrome D1 heme domain Gmad1 PF10647.9 ETS83080.1 - 3.9e-06 26.8 5.6 0.44 10.3 0.0 5.4 4 2 2 6 6 6 2 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.9 ETS83080.1 - 4e-06 26.4 11.0 7.3 6.4 0.0 8.1 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature Nup160 PF11715.8 ETS83080.1 - 3.9e-05 22.5 12.5 0.42 9.2 0.0 5.5 4 2 2 7 7 7 2 Nucleoporin Nup120/160 AAA_16 PF13191.6 ETS83080.1 - 0.00051 20.5 0.0 0.0018 18.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain RAB3GAP2_N PF14655.6 ETS83080.1 - 0.00088 18.6 0.0 0.51 9.5 0.0 3.9 4 0 0 4 4 4 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Frtz PF11768.8 ETS83080.1 - 0.0047 15.3 0.0 6.1 5.0 0.0 4.6 5 1 1 6 6 6 1 WD repeat-containing and planar cell polarity effector protein Fritz Robl_LC7 PF03259.17 ETS83080.1 - 0.0051 16.6 0.0 6.2 6.7 0.0 4.6 6 0 0 6 6 5 1 Roadblock/LC7 domain DUF5570 PF17731.1 ETS83080.1 - 0.0089 16.1 12.8 6.3 6.9 0.0 6.8 5 3 2 7 7 6 1 Family of unknown function (DUF5570) RNA_helicase PF00910.22 ETS83080.1 - 0.0096 16.3 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase PALB2_WD40 PF16756.5 ETS83080.1 - 0.033 13.1 0.7 24 3.7 0.0 4.1 5 0 0 5 5 5 0 Partner and localizer of BRCA2 WD40 domain Ploopntkinase3 PF18751.1 ETS83080.1 - 0.037 13.9 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ResIII PF04851.15 ETS83080.1 - 0.063 13.3 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3748 PF12566.8 ETS83080.1 - 0.069 13.1 0.1 36 4.3 0.0 4.9 4 2 1 5 5 4 0 Protein of unknown function (DUF3748) Roc PF08477.13 ETS83080.1 - 0.089 13.0 1.0 12 6.2 0.0 4.8 6 1 1 7 7 6 0 Ras of Complex, Roc, domain of DAPkinase DUF676 PF05057.14 ETS83080.1 - 0.15 11.6 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DPPIV_N PF00930.21 ETS83080.1 - 0.16 10.7 0.2 36 2.9 0.0 4.5 4 2 0 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region AAA_19 PF13245.6 ETS83080.1 - 0.18 12.1 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain WD40_like PF17005.5 ETS83080.1 - 0.25 10.6 0.0 1.7 7.9 0.0 2.5 3 0 0 3 3 3 0 WD40-like domain DUF1993 PF09351.10 ETS83082.1 - 1.8e-42 145.3 0.0 2e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Shikimate_dh_N PF08501.11 ETS83083.1 - 4e-17 62.2 0.0 1.4e-16 60.5 0.0 2.0 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 ETS83083.1 - 5.9e-15 55.7 0.0 1.1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase DHquinase_I PF01487.15 ETS83083.1 - 2.6e-14 54.0 0.0 1.2e-13 51.9 0.0 1.8 2 0 0 2 2 2 1 Type I 3-dehydroquinase Shikimate_DH PF01488.20 ETS83083.1 - 3.5e-07 30.4 0.0 7.2e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 ETS83083.1 - 0.017 14.9 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain Peripla_BP_3 PF13377.6 ETS83083.1 - 0.02 15.2 0.0 0.054 13.8 0.0 1.7 1 0 0 1 1 1 0 Periplasmic binding protein-like domain Rsa3 PF14615.6 ETS83083.1 - 0.083 12.5 0.0 0.23 11.0 0.0 1.8 1 0 0 1 1 1 0 Ribosome-assembly protein 3 F420_oxidored PF03807.17 ETS83083.1 - 0.15 12.7 0.0 0.41 11.3 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Zn_clus PF00172.18 ETS83084.1 - 2.1e-06 27.8 10.9 3.1e-06 27.2 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PQ-loop PF04193.14 ETS83088.1 - 8.1e-16 57.5 18.3 9.2e-14 51.0 0.8 2.9 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 ETS83088.1 - 0.00098 20.0 0.3 0.0032 18.3 0.0 2.0 2 1 1 3 3 3 1 ER lumen protein retaining receptor DUF92 PF01940.16 ETS83088.1 - 0.0096 15.4 0.8 0.093 12.1 0.3 2.5 3 0 0 3 3 3 1 Integral membrane protein DUF92 Jiraiya PF15038.6 ETS83088.1 - 0.08 12.4 2.8 0.43 10.0 0.2 2.7 2 1 1 3 3 3 0 Jiraiya Vps55 PF04133.14 ETS83088.1 - 0.47 10.4 11.3 0.97 9.4 0.1 2.9 3 1 0 3 3 3 0 Vacuolar protein sorting 55 DUF3742 PF12553.8 ETS83088.1 - 2.3 8.3 7.0 3 8.0 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) SH3_9 PF14604.6 ETS83089.1 - 2.9e-05 23.8 0.2 5.5e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SARAF PF06682.12 ETS83089.1 - 0.00014 21.6 0.9 0.00032 20.5 0.9 1.6 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis SH3_1 PF00018.28 ETS83089.1 - 0.00032 20.2 0.1 0.00066 19.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain DUF5518 PF17647.1 ETS83089.1 - 0.016 15.4 4.6 1 9.5 2.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5518) DUF599 PF04654.12 ETS83089.1 - 0.029 13.8 0.7 0.048 13.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF599 MtrF PF09472.10 ETS83089.1 - 0.75 9.2 4.0 1.5 8.2 4.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PEP-CTERM PF07589.11 ETS83089.1 - 2.1 8.6 5.8 22 5.3 0.1 2.7 2 0 0 2 2 2 0 PEP-CTERM motif GST_C PF00043.25 ETS83090.1 - 8.8e-08 32.3 0.0 1.5e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ETS83090.1 - 1.2e-06 28.4 0.0 2.8e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ETS83090.1 - 1.4e-06 28.4 0.0 3.4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ETS83090.1 - 0.0027 18.0 0.0 0.019 15.3 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ETS83090.1 - 0.019 15.2 0.0 0.047 14.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ETS83090.1 - 0.087 13.2 0.0 0.2 12.1 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 ETS83090.1 - 0.11 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Ribonucleas_3_3 PF14622.6 ETS83091.1 - 9.3e-08 32.3 0.0 0.011 15.9 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 ETS83091.1 - 0.00019 22.0 0.0 0.0011 19.6 0.0 2.3 2 1 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.26 ETS83091.1 - 0.0035 18.0 0.0 0.0088 16.7 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif PLA2_B PF01735.18 ETS83093.1 - 1.1e-28 100.0 0.0 2e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Lysophospholipase catalytic domain RE_NgoPII PF09521.10 ETS83093.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 NgoPII restriction endonuclease Ctr PF04145.15 ETS83094.1 - 3.9e-14 53.5 0.1 4.9e-14 53.2 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Peroxidase_2 PF01328.17 ETS83096.1 - 1.1e-51 176.1 0.2 1.4e-51 175.7 0.2 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 TNV_CP PF03898.13 ETS83096.1 - 0.011 15.0 0.1 0.021 14.1 0.1 1.4 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein DIOX_N PF14226.6 ETS83097.1 - 4.9e-27 95.0 0.1 7.7e-27 94.4 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS83097.1 - 1.4e-19 70.5 0.0 2.7e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.15 ETS83098.1 - 7e-103 344.7 33.9 8.1e-103 344.5 33.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cpta_toxin PF07254.12 ETS83098.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Membrane-bound toxin component of toxin-antitoxin system FAD_binding_3 PF01494.19 ETS83099.1 - 5e-58 197.0 0.0 7.2e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS83099.1 - 1.3e-05 25.0 1.2 0.0004 20.1 0.7 2.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS83099.1 - 5.4e-05 22.1 0.0 0.099 11.3 0.0 2.4 3 0 0 3 3 3 2 HI0933-like protein ApbA PF02558.16 ETS83099.1 - 0.0012 18.5 0.1 0.26 10.9 0.0 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 ETS83099.1 - 0.0023 17.2 0.0 1.7 7.8 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS83099.1 - 0.0055 16.9 0.0 0.017 15.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ETS83099.1 - 0.0062 15.6 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ETS83099.1 - 0.049 12.9 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ETS83099.1 - 0.062 12.3 0.1 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox PF00070.27 ETS83099.1 - 0.075 13.6 0.0 4 8.1 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS83099.1 - 0.08 12.2 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Glu_dehyd_C PF16912.5 ETS83099.1 - 0.09 12.3 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus K_oxygenase PF13434.6 ETS83099.1 - 0.2 10.8 0.0 0.36 9.9 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) adh_short PF00106.25 ETS83100.1 - 4.5e-47 160.0 0.2 5.8e-47 159.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS83100.1 - 2.7e-37 128.6 0.0 3.4e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS83100.1 - 5.7e-10 39.4 0.5 7.9e-10 38.9 0.5 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS83100.1 - 0.03 13.8 0.3 0.049 13.1 0.3 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ETS83100.1 - 0.032 13.4 0.1 0.061 12.4 0.1 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 ETS83100.1 - 0.082 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ETS83100.1 - 0.13 12.4 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_6 PF12697.7 ETS83101.1 - 7.4e-11 43.1 1.3 7.4e-11 43.1 1.3 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS83101.1 - 1.4e-10 40.8 0.1 6.7e-10 38.6 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS83101.1 - 3.6e-06 26.8 0.1 7.9e-06 25.7 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 ETS83101.1 - 0.014 15.2 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1100 PF06500.11 ETS83101.1 - 0.078 11.8 0.0 0.091 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF818 PF05677.12 ETS83101.1 - 0.089 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Gam PF06064.11 ETS83101.1 - 0.17 12.1 0.0 0.46 10.7 0.0 1.7 1 0 0 1 1 1 0 Host-nuclease inhibitor protein Gam zf-C2H2 PF00096.26 ETS83102.1 - 2.1e-14 53.0 21.8 7.7e-05 22.9 1.3 5.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS83102.1 - 5.6e-09 36.1 19.4 0.0007 20.2 0.6 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ETS83102.1 - 0.007 16.3 6.0 0.03 14.3 0.2 3.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ETS83102.1 - 0.0095 16.3 2.7 0.0095 16.3 2.7 4.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ETS83102.1 - 0.021 15.1 9.6 0.62 10.4 0.5 4.0 4 1 1 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ETS83102.1 - 0.24 11.2 11.1 0.046 13.5 2.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-BED PF02892.15 ETS83102.1 - 0.98 9.5 14.1 0.2 11.7 5.2 3.3 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_aberr PF17017.5 ETS83102.1 - 1.8 8.7 8.7 0.32 11.1 0.4 2.5 2 1 1 3 3 3 0 Aberrant zinc-finger zf-met PF12874.7 ETS83102.1 - 2.1 8.8 6.6 8.1 7.0 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ETS83102.1 - 3.7 7.4 8.5 1.7 8.5 0.2 3.7 3 0 0 3 3 3 0 zinc-finger C2H2-type CFEM PF05730.11 ETS83104.1 - 0.019 15.1 8.0 0.051 13.7 8.0 1.7 1 0 0 1 1 1 0 CFEM domain GMC_oxred_N PF00732.19 ETS83105.1 - 3.4e-31 108.7 0.0 1.2e-27 97.1 0.0 2.4 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS83105.1 - 3.1e-25 89.4 0.0 5.6e-25 88.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 ETS83105.1 - 0.00027 21.1 0.0 0.0012 19.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS83105.1 - 0.048 12.9 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS83105.1 - 0.13 11.2 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Med4 PF10018.9 ETS83106.1 - 1.6e-42 145.4 9.0 1.6e-42 145.4 9.0 2.0 1 1 1 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 SART-1 PF03343.13 ETS83106.1 - 6.4e-05 21.7 7.2 7.7e-05 21.5 7.2 1.1 1 0 0 1 1 1 1 SART-1 family Rrn6 PF10214.9 ETS83106.1 - 0.019 13.5 6.2 0.02 13.5 6.2 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor UDPG_MGDP_dh_C PF03720.15 ETS83106.1 - 0.12 12.8 0.1 0.26 11.7 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Peptidase_M30 PF10460.9 ETS83106.1 - 0.24 10.3 0.5 0.36 9.7 0.5 1.2 1 0 0 1 1 1 0 Peptidase M30 MAP7 PF05672.11 ETS83106.1 - 0.38 10.4 29.1 0.029 14.1 24.0 1.7 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family DUF4407 PF14362.6 ETS83106.1 - 2.9 7.2 16.4 0.89 8.8 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DDRGK PF09756.9 ETS83106.1 - 7.4 6.1 19.2 13 5.3 19.2 1.3 1 0 0 1 1 1 0 DDRGK domain Tho2 PF11262.8 ETS83106.1 - 7.8 5.6 7.5 12 5.0 5.7 1.8 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 QCR10 PF09796.9 ETS83107.1 - 9.7e-27 92.8 0.2 1.2e-26 92.5 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DHO_dh PF01180.21 ETS83108.1 - 2.5e-64 217.3 0.1 2.1e-52 178.2 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase FMN_dh PF01070.18 ETS83108.1 - 0.004 16.2 0.0 0.047 12.7 0.0 2.3 2 1 0 2 2 2 1 FMN-dependent dehydrogenase PcrB PF01884.17 ETS83108.1 - 0.072 12.5 0.9 1.6 8.2 0.1 2.4 2 0 0 2 2 2 0 PcrB family DIE2_ALG10 PF04922.12 ETS83109.1 - 3.5e-122 408.5 15.1 4.4e-122 408.2 15.1 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family DUF4131 PF13567.6 ETS83109.1 - 9.8 5.8 9.2 25 4.5 0.6 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) FAM199X PF15814.5 ETS83110.1 - 6.4 5.7 7.3 8.1 5.4 7.3 1.1 1 0 0 1 1 1 0 Protein family FAM199X Coatomer_WDAD PF04053.14 ETS83111.1 - 1.1e-167 558.7 0.0 3.9e-167 556.8 0.0 1.9 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 ETS83111.1 - 7.6e-35 118.4 7.2 1.6e-05 25.6 0.3 8.4 8 0 0 8 8 8 5 WD domain, G-beta repeat Nup160 PF11715.8 ETS83111.1 - 3.2e-06 26.1 1.3 0.061 12.0 0.1 4.1 2 1 2 4 4 4 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 ETS83111.1 - 1.2e-05 25.5 0.0 5.1 7.5 0.0 5.6 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Mannitol_dh_C PF08125.13 ETS83112.1 - 4.9e-43 147.4 0.4 7.1e-43 146.9 0.4 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 ETS83112.1 - 3.5e-19 69.5 2.4 7.3e-19 68.4 0.1 2.3 2 1 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.14 ETS83112.1 - 0.0013 18.3 1.9 0.0019 17.8 0.1 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UxaC PF02614.14 ETS83112.1 - 0.045 12.6 0.1 0.086 11.7 0.1 1.4 1 1 0 1 1 1 0 Glucuronate isomerase Ank_4 PF13637.6 ETS83113.1 - 8.1e-19 67.7 0.6 2e-07 31.4 0.1 5.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS83113.1 - 3.4e-18 66.0 0.1 4.7e-11 43.1 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 ETS83113.1 - 1.1e-13 50.9 3.1 0.0067 16.8 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 ETS83113.1 - 1.6e-10 40.3 1.9 0.13 12.9 0.0 6.4 6 0 0 6 6 5 2 Ankyrin repeat AAA_16 PF13191.6 ETS83113.1 - 8.6e-09 36.0 0.2 5e-08 33.5 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain Ank_5 PF13857.6 ETS83113.1 - 2.3e-07 30.9 4.8 2.3e-05 24.6 0.1 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) NACHT PF05729.12 ETS83113.1 - 7.3e-07 29.3 0.0 1.9e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NACHT_N PF17100.5 ETS83113.1 - 3.6e-06 27.0 0.2 1e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase AAA_22 PF13401.6 ETS83113.1 - 0.001 19.4 0.0 0.005 17.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 ETS83113.1 - 0.0036 16.6 1.0 0.022 14.0 0.3 2.0 1 1 1 2 2 2 1 KAP family P-loop domain Viral_helicase1 PF01443.18 ETS83113.1 - 0.0086 15.8 1.3 3 7.5 0.1 2.4 1 1 1 2 2 2 2 Viral (Superfamily 1) RNA helicase PLN_propep PF16485.5 ETS83113.1 - 0.03 14.0 0.0 0.094 12.4 0.0 1.8 1 0 0 1 1 1 0 Protealysin propeptide Fimbrial_CS1 PF04449.12 ETS83113.1 - 0.032 14.4 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 CS1 type fimbrial major subunit AAA PF00004.29 ETS83113.1 - 0.14 12.6 0.1 0.61 10.5 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DOG1 PF14144.6 ETS83113.1 - 0.38 11.0 2.6 39 4.6 0.0 3.5 4 0 0 4 4 4 0 Seed dormancy control Glyco_hydro_3_C PF01915.22 ETS83114.1 - 6.1e-45 153.7 0.0 9.6e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ETS83114.1 - 1.4e-22 79.5 0.2 2.7e-22 78.7 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 ETS83114.1 - 1.3e-13 51.0 0.0 3e-13 49.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain MFS_1 PF07690.16 ETS83115.1 - 5e-25 88.2 55.2 5.9e-19 68.2 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_1 PF00583.25 ETS83116.1 - 1.5e-10 41.3 0.0 2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS83116.1 - 7.5e-10 38.8 0.3 1.3e-09 38.0 0.3 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS83116.1 - 1.6e-08 34.8 1.3 4.2e-08 33.5 1.3 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS83116.1 - 9.8e-07 28.7 0.0 1.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 ETS83116.1 - 0.0052 16.9 0.1 0.01 16.0 0.1 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 ETS83116.1 - 0.0069 17.1 0.0 0.01 16.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ETS83116.1 - 0.022 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ETS83116.1 - 0.042 14.0 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETS83116.1 - 0.065 13.3 0.0 3 8.0 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 ETS83116.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.24 ETS83117.1 - 2.6e-88 296.9 18.6 3.1e-88 296.6 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS83117.1 - 4.6e-23 81.7 40.7 7.9e-19 67.8 6.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Git3 PF11710.8 ETS83118.1 - 7.3e-56 189.2 15.3 1.1e-55 188.6 15.3 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 ETS83118.1 - 5.5e-18 64.8 0.8 5.5e-18 64.8 0.8 2.4 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 ETS83118.1 - 1.3e-07 31.2 0.0 1.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Tmemb_161AB PF10268.9 ETS83118.1 - 0.0014 17.3 0.0 7.8 5.0 0.0 3.0 3 0 0 3 3 3 3 Predicted transmembrane protein 161AB Spo7 PF03907.13 ETS83118.1 - 0.01 15.4 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 0 Spo7-like protein DUF2157 PF09925.9 ETS83118.1 - 0.038 13.8 2.5 0.22 11.3 0.0 3.0 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) GATase PF00117.28 ETS83119.1 - 9.7e-13 48.3 0.0 1.3e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ETS83119.1 - 0.036 13.8 1.1 0.45 10.2 1.1 2.5 1 1 0 1 1 1 0 Peptidase C26 SNF2_N PF00176.23 ETS83120.1 - 1.5e-51 175.2 0.0 2.3e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS83120.1 - 2.5e-14 53.5 0.0 5.5e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS83120.1 - 3.6e-10 40.1 0.0 2.8e-09 37.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 ETS83120.1 - 5.5e-06 26.2 4.1 1.2e-05 25.1 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 ETS83120.1 - 1.8e-05 24.6 0.0 4.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 ETS83120.1 - 2.6e-05 24.5 3.7 9.9e-05 22.6 3.7 2.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ETS83120.1 - 0.00042 20.3 3.2 0.0012 18.8 3.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ETS83120.1 - 0.0023 17.8 1.5 0.0023 17.8 1.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 ETS83120.1 - 0.0039 16.4 0.0 0.0074 15.5 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4 PF00097.25 ETS83120.1 - 0.0041 17.0 3.0 0.012 15.4 3.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ETS83120.1 - 0.012 15.6 4.5 0.031 14.2 4.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Spectrin PF00435.21 ETS83120.1 - 0.051 14.1 0.3 0.19 12.2 0.0 2.1 2 0 0 2 2 1 0 Spectrin repeat zf-RING_10 PF16685.5 ETS83120.1 - 0.13 12.4 4.5 0.4 10.8 4.0 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 ETS83120.1 - 0.19 11.9 4.3 0.49 10.6 4.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ABC_tran_CTD PF16326.5 ETS83120.1 - 0.22 11.8 1.1 0.81 10.0 1.1 2.0 1 0 0 1 1 1 0 ABC transporter C-terminal domain Prok-RING_4 PF14447.6 ETS83120.1 - 0.37 10.7 4.3 0.84 9.6 4.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Pyr_redox_2 PF07992.14 ETS83121.1 - 3.7e-11 42.8 0.0 6.4e-06 25.6 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS83121.1 - 9.6e-11 41.5 0.1 0.00039 19.8 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS83121.1 - 1.3e-07 31.1 0.0 0.00087 18.5 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 ETS83121.1 - 0.00094 18.3 0.0 0.0029 16.7 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 ETS83121.1 - 0.0013 18.1 1.4 0.016 14.4 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 ETS83121.1 - 0.0025 18.0 0.7 0.069 13.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS83121.1 - 0.0046 16.6 3.9 0.22 11.0 0.9 3.7 2 2 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS83121.1 - 0.0052 17.3 1.1 5.8 7.5 0.1 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS83121.1 - 0.0087 16.1 0.2 0.19 11.7 0.2 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 ETS83121.1 - 0.033 12.9 0.0 0.19 10.4 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 ETS83121.1 - 0.096 11.7 1.3 0.14 11.2 0.3 1.8 2 0 0 2 2 2 0 FAD binding domain DUF1713 PF08213.11 ETS83121.1 - 0.21 11.6 14.4 0.037 14.0 6.0 2.3 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1713) DUF2196 PF09962.9 ETS83122.1 - 6.8e-23 80.4 4.2 1.1e-22 79.8 4.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) zf-Di19 PF05605.12 ETS83122.1 - 0.16 12.3 0.6 0.27 11.5 0.4 1.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding GMP_synt_C PF00958.22 ETS83123.1 - 2e-33 114.3 0.0 3.8e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 ETS83123.1 - 3.6e-31 108.4 0.0 5.6e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 ETS83123.1 - 9.2e-09 34.8 0.0 3.3e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 ETS83123.1 - 1.3e-05 25.1 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 ETS83123.1 - 0.0032 16.3 0.1 0.0072 15.2 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 ETS83123.1 - 0.0094 15.5 0.0 0.074 12.5 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 ETS83123.1 - 0.041 13.2 0.0 0.097 11.9 0.0 1.6 2 0 0 2 2 2 0 Arginosuccinate synthase PAPS_reduct PF01507.19 ETS83123.1 - 0.051 13.6 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 ETS83123.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 PP-loop family ThiI PF02568.14 ETS83123.1 - 0.12 12.0 0.0 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) NmrA PF05368.13 ETS83124.1 - 5.3e-13 49.1 0.0 7.2e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS83124.1 - 5.4e-12 46.0 0.0 1.7e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 ETS83124.1 - 0.015 15.8 0.1 0.033 14.6 0.1 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 ETS83124.1 - 0.016 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family peroxidase PF00141.23 ETS83125.1 - 1.1e-23 84.1 0.0 1.7e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase His_Phos_2 PF00328.22 ETS83126.1 - 3.8e-63 214.1 0.0 4.6e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) FolB PF02152.18 ETS83126.1 - 0.15 12.6 0.0 0.27 11.8 0.0 1.3 1 0 0 1 1 1 0 Dihydroneopterin aldolase NPF PF16601.5 ETS83127.1 - 0.1 13.1 4.3 0.29 11.6 0.8 2.2 2 0 0 2 2 2 0 Rabosyn-5 repeating NPF sequence-motif Inositol_P PF00459.25 ETS83128.1 - 1.2e-63 215.2 0.0 1.4e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.16 ETS83130.1 - 2.9e-33 115.3 21.6 1.7e-27 96.3 2.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS83130.1 - 1.1e-08 34.4 3.3 1.1e-08 34.4 3.3 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 ETS83130.1 - 0.0024 16.8 3.0 0.0024 16.8 3.0 2.7 2 1 0 2 2 2 1 MFS_1 like family DUF3902 PF13042.6 ETS83130.1 - 0.24 11.0 6.2 0.029 14.0 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3902) HTH_23 PF13384.6 ETS83131.1 - 0.01 15.6 0.1 0.034 13.9 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 ETS83131.1 - 0.018 15.2 0.2 0.079 13.1 0.2 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain MRP-S26 PF14943.6 ETS83131.1 - 0.32 10.9 14.0 14 5.5 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 End3 PF12761.7 ETS83133.1 - 8.8e-79 264.3 2.5 1.2e-78 263.9 2.5 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 ETS83133.1 - 2.3e-47 159.2 0.0 5.5e-46 154.8 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 ETS83133.1 - 1.7e-06 27.2 0.5 4.9e-06 25.7 0.5 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 ETS83133.1 - 4.7e-05 23.7 0.1 0.00033 21.0 0.0 2.5 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 ETS83133.1 - 0.00077 19.3 0.2 0.0015 18.3 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 ETS83133.1 - 0.034 14.1 0.1 0.18 11.8 0.1 2.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 ETS83133.1 - 0.051 13.1 0.9 0.14 11.7 0.2 2.1 2 0 0 2 2 2 0 EF hand MLD PF11647.8 ETS83133.1 - 0.11 12.8 0.1 0.26 11.6 0.1 1.6 1 0 0 1 1 1 0 Membrane Localization Domain UPF0242 PF06785.11 ETS83133.1 - 0.41 10.7 6.0 0.92 9.6 6.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MerR-DNA-bind PF09278.11 ETS83133.1 - 7.9 7.1 7.9 2.5 8.7 0.1 3.3 3 1 0 3 3 3 0 MerR, DNA binding Pyr_redox_2 PF07992.14 ETS83134.1 - 8e-34 117.2 1.6 1e-33 116.9 1.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS83134.1 - 3.8e-10 40.2 0.8 4.6e-07 30.3 0.5 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS83134.1 - 0.0003 20.2 0.5 0.0038 16.5 0.1 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS83134.1 - 0.0085 15.2 0.1 0.45 9.5 0.0 2.7 2 1 1 3 3 3 1 Lycopene cyclase protein K_oxygenase PF13434.6 ETS83134.1 - 0.042 13.0 1.0 0.12 11.4 0.1 2.1 2 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ETS83134.1 - 0.061 13.3 0.7 29 4.6 0.0 3.5 3 1 1 4 4 4 0 FAD-NAD(P)-binding ACBP PF00887.19 ETS83135.1 - 7.6e-21 74.1 2.2 8.9e-21 73.9 2.2 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Tyr-DNA_phospho PF06087.12 ETS83136.1 - 6.4e-163 542.6 0.0 7.3e-163 542.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 ETS83136.1 - 0.091 12.7 1.0 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 PLD-like domain Thioredoxin PF00085.20 ETS83137.1 - 1.3e-44 150.4 0.2 8.7e-26 89.9 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 ETS83137.1 - 1.3e-08 35.0 0.0 0.018 15.0 0.0 3.5 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ETS83137.1 - 7.2e-07 29.5 0.7 0.21 12.0 0.0 3.8 3 1 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 ETS83137.1 - 8.9e-05 22.4 1.2 0.007 16.3 0.0 3.2 3 0 0 3 3 3 1 AhpC/TSA family Thioredoxin_2 PF13098.6 ETS83137.1 - 0.0011 19.3 2.1 0.73 10.3 0.1 3.7 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 ETS83137.1 - 0.012 15.8 0.5 0.31 11.3 0.2 3.0 3 0 0 3 3 2 0 Thioredoxin-like TraF PF13728.6 ETS83137.1 - 0.015 15.2 0.0 0.015 15.2 0.0 3.4 4 0 0 4 4 3 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 ETS83137.1 - 0.047 13.7 0.2 0.64 10.1 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin domain OST3_OST6 PF04756.13 ETS83137.1 - 0.052 12.9 0.2 16 4.7 0.1 2.9 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family 7TM_GPCR_Srh PF10318.9 ETS83137.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh Presenilin PF01080.17 ETS83137.1 - 0.18 10.6 0.2 0.29 9.8 0.2 1.2 1 0 0 1 1 1 0 Presenilin CFIA_Pcf11 PF11526.8 ETS83137.1 - 0.43 11.1 4.2 1.1 9.7 4.2 1.7 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 DUF966 PF06136.13 ETS83137.1 - 1.1 8.8 5.4 2.2 7.9 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Carb_anhydrase PF00194.21 ETS83138.1 - 4.1e-21 75.7 0.0 5e-20 72.1 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF4551 PF15087.6 ETS83139.1 - 1.1 8.0 9.1 1.4 7.6 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ndc1_Nup PF09531.10 ETS83139.1 - 2.7 6.6 8.0 3.4 6.2 8.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup XRCC4 PF06632.12 ETS83139.1 - 8.4 5.1 15.8 17 4.2 15.8 1.5 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 L27_1 PF09058.10 ETS83140.1 - 0.03 14.3 1.7 0.063 13.3 0.5 2.1 2 0 0 2 2 2 0 L27_1 Chitin_synth_2 PF03142.15 ETS83141.1 - 2.3e-21 76.1 5.5 4.1e-21 75.2 4.0 3.1 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ETS83141.1 - 1.7e-16 60.7 6.7 1.7e-16 60.7 6.7 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ETS83141.1 - 2e-12 47.5 0.0 4.8e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ETS83141.1 - 0.036 13.9 0.2 7.1 6.4 0.2 2.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 CybS PF05328.12 ETS83141.1 - 0.043 13.5 0.3 0.098 12.3 0.3 1.7 1 0 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit Squash PF00299.18 ETS83141.1 - 0.26 11.3 0.8 0.82 9.7 0.4 2.0 2 0 0 2 2 2 0 Squash family serine protease inhibitor DUF4481 PF14800.6 ETS83141.1 - 7.4 5.9 7.2 13 5.2 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) MIF4G PF02854.19 ETS83142.1 - 7.8e-53 179.3 0.0 2.1e-24 86.3 0.0 3.6 3 1 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 ETS83142.1 - 8.7e-41 139.8 11.2 8.7e-41 139.8 11.2 2.2 2 0 0 2 2 2 1 Up-frameshift suppressor 2 CBP4 PF07960.11 ETS83142.1 - 0.047 13.6 0.8 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 CBP4 Mo-co_dimer PF03404.16 ETS83143.1 - 2.6e-62 208.9 0.3 4.6e-62 208.1 0.3 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 ETS83143.1 - 6e-56 188.7 0.0 9.9e-56 188.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 ETS83143.1 - 2.1e-33 114.6 0.0 6.6e-33 113.0 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ETS83143.1 - 1.9e-26 92.8 0.0 3.9e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 ETS83143.1 - 8.7e-21 73.9 0.0 1.6e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 ETS83143.1 - 0.0011 19.1 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain MARVEL PF01284.23 ETS83146.1 - 0.00012 22.1 20.8 0.00019 21.5 20.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain PKcGMP_CC PF16808.5 ETS83148.1 - 7e-05 22.6 3.9 0.00013 21.7 3.9 1.4 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase bZIP_2 PF07716.15 ETS83148.1 - 0.00023 21.2 13.0 0.00067 19.7 13.0 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ETS83148.1 - 0.022 14.9 9.1 0.045 13.8 9.1 1.5 1 0 0 1 1 1 0 bZIP transcription factor UPF0242 PF06785.11 ETS83148.1 - 0.15 12.1 2.4 0.29 11.2 2.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Uds1 PF15456.6 ETS83148.1 - 0.49 10.6 9.4 1.4 9.1 9.4 1.7 1 0 0 1 1 1 0 Up-regulated During Septation DUF641 PF04859.12 ETS83148.1 - 1.2 9.4 9.5 0.45 10.9 6.8 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) UIM PF02809.20 ETS83149.1 - 0.73 9.9 0.2 0.73 9.9 0.2 2.9 3 0 0 3 3 3 0 Ubiquitin interaction motif CDH-cyt PF16010.5 ETS83151.1 - 1.5e-67 226.8 4.8 1.5e-67 226.8 4.8 2.2 3 0 0 3 3 3 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_C PF05199.13 ETS83151.1 - 1.4e-24 87.2 0.4 3.3e-24 86.0 0.4 1.7 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 ETS83151.1 - 1.3e-23 83.9 0.0 2.9e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.18 ETS83151.1 - 6.1e-12 45.3 11.4 1.8e-11 43.8 11.4 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_2 PF00890.24 ETS83151.1 - 8e-10 38.4 0.1 0.00036 19.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS83151.1 - 5.8e-05 23.2 0.0 0.00017 21.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DOMON PF03351.17 ETS83151.1 - 0.00085 19.5 0.1 0.0042 17.3 0.0 2.2 1 1 0 1 1 1 1 DOMON domain HI0933_like PF03486.14 ETS83151.1 - 0.0028 16.4 0.0 0.0055 15.5 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 ETS83151.1 - 0.0045 16.3 0.0 0.009 15.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS83151.1 - 0.0053 16.1 0.1 0.0094 15.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ETS83151.1 - 0.012 14.9 0.5 0.025 13.8 0.5 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS83151.1 - 0.018 14.1 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 ETS83151.1 - 0.033 14.7 0.0 0.82 10.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS83151.1 - 0.058 12.6 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 ETS83151.1 - 0.22 10.8 4.4 0.52 9.6 0.0 2.9 3 1 1 4 4 3 0 FAD dependent oxidoreductase Aldose_epim PF01263.20 ETS83152.1 - 5.2e-46 157.3 0.5 6e-46 157.1 0.5 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF1629 PF07791.11 ETS83152.1 - 0.04 14.0 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1629) ABC_tran PF00005.27 ETS83153.1 - 1.5e-40 138.9 0.0 9.9e-21 74.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS83153.1 - 1.2e-37 130.0 28.0 2.6e-27 96.2 11.4 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.6 ETS83153.1 - 9.7e-08 32.6 0.6 0.0016 18.8 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ETS83153.1 - 5.3e-07 29.7 0.5 0.045 13.6 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase SMC_N PF02463.19 ETS83153.1 - 1.6e-06 27.7 1.4 0.036 13.5 0.3 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ETS83153.1 - 5.2e-05 23.5 0.5 0.35 11.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 ETS83153.1 - 0.00041 19.5 0.1 0.013 14.6 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 ETS83153.1 - 0.0019 17.9 0.3 0.93 9.3 0.1 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_7 PF12775.7 ETS83153.1 - 0.0063 16.0 0.3 2.3 7.7 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 ETS83153.1 - 0.01 15.4 0.3 2.9 7.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ETS83153.1 - 0.016 15.3 0.4 1.9 8.6 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 ETS83153.1 - 0.025 14.7 0.5 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 Dynamin family DnaB_C PF03796.15 ETS83153.1 - 0.029 13.7 0.1 3.4 6.9 0.0 2.4 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_21 PF13304.6 ETS83153.1 - 0.038 13.8 3.6 26 4.5 0.2 3.9 2 2 2 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 ETS83153.1 - 0.046 13.9 0.3 0.39 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 ETS83153.1 - 0.076 13.3 0.2 0.076 13.3 0.2 3.0 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 ETS83153.1 - 0.13 12.7 0.7 8.7 6.8 0.0 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 ETS83153.1 - 0.2 12.1 1.4 10 6.6 0.1 2.5 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 ETS83153.1 - 0.31 10.3 2.7 15 4.8 0.0 3.0 3 1 0 3 3 3 0 FtsK/SpoIIIE family Mpv17_PMP22 PF04117.12 ETS83154.1 - 1.5e-14 53.9 1.9 1.5e-14 53.9 1.9 2.2 1 1 1 2 2 2 1 Mpv17 / PMP22 family DUF5527 PF17665.1 ETS83154.1 - 0.074 12.6 0.0 0.22 11.0 0.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5527) DUF1961 PF09224.11 ETS83155.1 - 1.3e-98 328.7 0.0 1.5e-98 328.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1961) PDZ_1 PF12812.7 ETS83156.1 - 1.1e-54 182.3 0.0 4.5e-34 116.3 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 ETS83156.1 - 2.9e-28 99.7 0.8 3.7e-22 79.8 0.1 2.4 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 ETS83156.1 - 8.8e-14 51.1 0.0 0.00016 21.5 0.1 4.0 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 ETS83156.1 - 7.8e-13 48.6 3.0 0.00037 20.8 0.0 4.7 5 0 0 5 5 5 3 PDZ domain PDZ PF00595.24 ETS83156.1 - 8.2e-11 42.1 0.0 0.00098 19.4 0.0 3.7 3 0 0 3 3 3 3 PDZ domain 4HPAD_g_N PF18671.1 ETS83156.1 - 0.0012 18.5 0.0 0.011 15.4 0.0 2.5 2 0 0 2 2 2 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Trypsin PF00089.26 ETS83156.1 - 0.0015 18.4 0.0 0.0045 16.8 0.0 1.8 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 ETS83156.1 - 0.0081 16.1 0.4 6 6.9 0.1 4.1 4 0 0 4 4 4 1 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 ETS83156.1 - 0.051 12.2 0.1 0.1 11.2 0.1 1.4 1 0 0 1 1 1 0 Peptidase S46 Hva1_TUDOR PF11160.8 ETS83156.1 - 0.16 12.2 0.3 0.6 10.3 0.1 2.1 2 0 0 2 2 2 0 Hypervirulence associated proteins TUDOR domain Peptidase_S7 PF00949.21 ETS83156.1 - 0.19 11.5 0.4 0.57 10.0 0.1 1.9 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease DUF1945 PF09178.10 ETS83157.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1945) Toxin_7 PF05980.12 ETS83157.1 - 2.1 8.6 10.5 6.6 7.1 10.5 2.0 1 0 0 1 1 1 0 Toxin 7 Tachystatin_B PF11478.8 ETS83157.1 - 2.2 8.3 7.8 1.4 8.9 4.9 2.1 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B PAP_assoc PF03828.19 ETS83159.1 - 9.3e-18 64.2 0.0 8.6e-12 45.1 0.0 2.7 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 ETS83159.1 - 0.00012 22.2 0.0 0.00039 20.7 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain TFIIF_alpha PF05793.12 ETS83160.1 - 3.5e-12 45.7 54.6 1.2e-11 43.9 54.6 1.7 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nre_C PF04895.12 ETS83160.1 - 0.065 13.2 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Archaeal Nre, C-terminal Bud13 PF09736.9 ETS83161.1 - 9.3e-46 155.8 5.4 9.3e-46 155.8 5.4 2.3 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex FAD_binding_4 PF01565.23 ETS83161.1 - 0.066 12.9 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Cytadhesin_P30 PF07271.11 ETS83161.1 - 0.072 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 LCM PF04072.14 ETS83162.1 - 1.2e-17 64.4 0.0 3.3e-17 63.0 0.0 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase FERM_F1 PF18379.1 ETS83163.1 - 0.0082 16.1 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 FERM F1 ubiquitin-like domain UL11 PF11094.8 ETS83163.1 - 0.074 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated tegument protein p450 PF00067.22 ETS83164.1 - 1.8e-31 109.4 0.0 3.3e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 DUF676 PF05057.14 ETS83166.1 - 3e-05 23.6 0.0 5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 ETS83166.1 - 0.00011 22.0 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 ETS83166.1 - 0.0026 18.4 0.0 0.0033 18.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 ETS83166.1 - 0.0063 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Cutinase Palm_thioest PF02089.15 ETS83166.1 - 0.025 14.4 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_8 PF06259.12 ETS83166.1 - 0.048 13.3 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Hydrolase_4 PF12146.8 ETS83166.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Aminotran_1_2 PF00155.21 ETS83168.1 - 1.1e-45 156.4 0.0 1.4e-45 156.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ETS83168.1 - 0.0037 16.6 0.0 0.0068 15.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase NIR_SIR_ferr PF03460.17 ETS83168.1 - 0.1 12.5 0.0 8.7 6.3 0.0 3.1 3 0 0 3 3 3 0 Nitrite/Sulfite reductase ferredoxin-like half domain DinB PF05163.12 ETS83169.1 - 2e-22 79.9 0.7 2.2e-22 79.7 0.7 1.0 1 0 0 1 1 1 1 DinB family DinB_2 PF12867.7 ETS83169.1 - 8.5e-10 39.2 0.5 9.9e-10 39.0 0.5 1.1 1 0 0 1 1 1 1 DinB superfamily Abhydrolase_3 PF07859.13 ETS83170.1 - 2.8e-48 164.6 0.0 3.7e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS83170.1 - 2.3e-08 33.4 0.1 1e-07 31.2 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.16 ETS83170.1 - 1.9e-05 24.6 0.0 8.2e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 ETS83170.1 - 0.00023 20.7 0.0 0.003 17.1 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 ETS83170.1 - 0.015 14.0 0.0 0.91 8.1 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 ETS83170.1 - 0.057 14.0 0.1 0.11 13.1 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family tRNA-synt_2 PF00152.20 ETS83171.1 - 3.4e-69 233.3 0.2 3.4e-69 233.3 0.2 2.1 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 ETS83171.1 - 1e-13 51.0 0.1 1e-13 51.0 0.1 1.5 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 ETS83171.1 - 4.3e-05 23.4 0.0 0.00019 21.4 0.0 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ETS83171.1 - 0.015 14.8 0.1 6.1 6.2 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Aminotran_3 PF00202.21 ETS83172.1 - 9.1e-88 294.6 0.1 1.1e-87 294.4 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Exo70 PF03081.15 ETS83173.1 - 3.8e-87 292.8 1.7 7.9e-87 291.7 0.1 2.0 2 1 0 2 2 2 1 Exo70 exocyst complex subunit Sec8_exocyst PF04048.14 ETS83173.1 - 0.0084 16.0 1.2 0.28 11.1 0.2 3.4 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain Apolipoprotein PF01442.18 ETS83173.1 - 0.075 12.9 0.2 0.075 12.9 0.2 3.0 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain MukF_M PF17192.4 ETS83173.1 - 0.35 10.6 2.3 16 5.2 0.1 3.1 2 1 1 3 3 3 0 MukF middle domain DUF2203 PF09969.9 ETS83173.1 - 1.2 9.9 5.3 0.47 11.2 0.2 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Methyltr_RsmB-F PF01189.17 ETS83174.1 - 6.2e-25 88.0 0.0 1.6e-24 86.6 0.0 1.7 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 ETS83174.1 - 0.00018 21.7 0.0 0.00035 20.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 ETS83174.1 - 0.13 12.0 0.0 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain 2_5_RNA_ligase2 PF13563.6 ETS83175.1 - 1.4e-28 99.7 1.3 1.9e-28 99.3 0.3 1.8 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily PAP_central PF04928.17 ETS83175.1 - 1.8e-25 89.4 0.0 3.4e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain MJ1316 PF04457.12 ETS83175.1 - 3.6e-19 69.3 0.2 8.6e-19 68.1 0.2 1.7 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Nrap_D2 PF17403.2 ETS83175.1 - 0.00016 21.5 0.0 0.00035 20.4 0.0 1.6 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain NTP_transf_2 PF01909.23 ETS83175.1 - 0.0023 18.2 0.0 0.0054 17.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Exo_endo_phos PF03372.23 ETS83175.1 - 0.0043 16.6 0.1 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Myc_N PF01056.18 ETS83175.1 - 0.17 11.7 4.3 0.23 11.3 3.4 1.6 2 0 0 2 2 2 0 Myc amino-terminal region Tub_N PF16322.5 ETS83175.1 - 0.3 11.5 5.6 0.56 10.6 5.6 1.4 1 0 0 1 1 1 0 Tubby N-terminal CPSF100_C PF13299.6 ETS83175.1 - 0.31 11.2 1.2 0.65 10.2 1.2 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Spt5_N PF11942.8 ETS83175.1 - 0.38 11.8 9.8 1.5 9.9 9.8 2.0 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal TLP-20 PF06088.11 ETS83175.1 - 0.52 10.2 5.7 0.97 9.3 5.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAM176 PF14851.6 ETS83175.1 - 1 9.0 4.1 2.6 7.7 4.1 1.6 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.16 ETS83175.1 - 1 8.5 3.9 2.1 7.5 3.9 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4637 PF15470.6 ETS83175.1 - 1.6 8.4 5.6 3.4 7.4 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) BUD22 PF09073.10 ETS83175.1 - 1.8 7.9 10.2 2.9 7.2 10.2 1.3 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 ETS83175.1 - 2 6.6 9.1 1 7.6 7.0 1.4 2 0 0 2 2 2 0 CDC45-like protein NOA36 PF06524.12 ETS83175.1 - 2.1 7.6 8.4 3.8 6.7 8.4 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 ETS83175.1 - 4.7 5.2 11.4 9.5 4.2 11.4 1.4 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 ETS83175.1 - 9 4.4 11.3 13 3.8 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family Aldo_ket_red PF00248.21 ETS83176.1 - 1.2e-66 225.0 0.0 1.3e-66 224.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family IMPa_N_2 PF18650.1 ETS83176.1 - 0.043 13.1 0.1 0.081 12.2 0.1 1.4 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain WD40 PF00400.32 ETS83177.1 - 1.7e-28 98.2 10.4 1.3e-06 29.0 0.5 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS83177.1 - 3.2e-08 33.7 0.0 0.13 12.6 0.0 4.5 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ETS83177.1 - 1.5e-06 27.2 1.8 0.15 10.7 0.1 4.6 3 2 2 5 5 5 2 Nucleoporin Nup120/160 DUF3929 PF13066.6 ETS83177.1 - 0.015 15.4 0.1 1.6 8.8 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3929) ATG16 PF08614.11 ETS83177.1 - 0.037 14.2 0.5 0.063 13.5 0.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) BBS2_Mid PF14783.6 ETS83177.1 - 0.055 13.5 0.0 0.57 10.2 0.0 2.7 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Hira PF07569.11 ETS83177.1 - 0.16 11.7 0.1 10 5.8 0.0 2.9 3 0 0 3 3 3 0 TUP1-like enhancer of split Mito_carr PF00153.27 ETS83177.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial carrier protein APG6_N PF17675.1 ETS83177.1 - 0.17 12.4 1.8 0.42 11.1 1.8 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region Suppressor_APC PF11414.8 ETS83177.1 - 0.58 10.3 6.1 0.26 11.4 0.8 2.5 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein CM_2 PF01817.21 ETS83178.1 - 0.59 10.5 2.6 4.7 7.6 0.1 2.8 2 2 0 2 2 2 0 Chorismate mutase type II BCIP PF13862.6 ETS83179.1 - 9.4e-69 231.3 0.1 1.2e-68 231.0 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Cyclin_N PF00134.23 ETS83180.1 - 0.00059 19.6 0.1 0.019 14.7 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain WD40 PF00400.32 ETS83182.1 - 1.3e-15 57.5 0.2 0.025 15.4 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS83182.1 - 0.01 16.1 0.0 20 5.5 0.0 3.8 2 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain ATP_bind_1 PF03029.17 ETS83183.1 - 1.1e-76 257.8 0.0 1.5e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 ETS83183.1 - 0.0017 17.4 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 ETS83183.1 - 0.0078 15.5 0.0 0.023 14.0 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.23 ETS83183.1 - 0.017 15.2 0.0 0.19 11.8 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.7 ETS83183.1 - 0.039 12.9 0.0 0.084 11.8 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain GTP_EFTU PF00009.27 ETS83183.1 - 0.053 13.1 0.0 0.33 10.4 0.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 ETS83183.1 - 0.079 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ImcF-related_N PF14331.6 ETS83183.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 ImcF-related N-terminal domain EF_TS PF00889.19 ETS83183.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Elongation factor TS RNase_P_Rpp14 PF01900.19 ETS83184.1 - 1e-35 122.0 0.0 1.4e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family MoCF_biosynth PF00994.24 ETS83185.1 - 5.3e-58 194.8 0.3 1.7e-29 102.4 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 ETS83185.1 - 6.3e-39 133.3 1.8 9.8e-39 132.6 1.8 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 ETS83185.1 - 4.4e-16 58.8 0.0 1.2e-15 57.4 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) T2SSE PF00437.20 ETS83185.1 - 0.13 11.3 0.4 2 7.4 0.1 2.5 2 1 1 3 3 3 0 Type II/IV secretion system protein SelP_N PF04592.14 ETS83185.1 - 5 6.5 12.3 7.8 5.8 12.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ATP-synt_C PF00137.21 ETS83187.1 - 8.3e-25 86.9 36.5 1.8e-15 57.0 11.9 3.0 3 0 0 3 3 3 2 ATP synthase subunit C SLATT_5 PF18160.1 ETS83187.1 - 0.015 14.6 0.9 0.057 12.7 0.0 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 tRNA_bind PF01588.20 ETS83188.1 - 7.3e-23 80.5 0.2 1.8e-22 79.2 0.2 1.7 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 ETS83188.1 - 0.029 14.4 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ETS83188.1 - 0.059 13.6 0.2 0.51 10.6 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF2486 PF10667.9 ETS83188.1 - 0.3 11.3 14.6 0.57 10.4 14.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) tRNA-synt_1g PF09334.11 ETS83189.1 - 0.33 9.6 0.6 0.38 9.4 0.6 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) RNA_pol PF00940.19 ETS83190.1 - 5e-185 615.2 0.0 7.2e-185 614.7 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 ETS83190.1 - 6.9e-97 324.8 0.7 1.3e-96 324.0 0.7 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal RsfS PF02410.15 ETS83191.1 - 4.8e-12 46.2 0.0 2.7e-11 43.8 0.0 2.3 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation mRNA_stabil PF13929.6 ETS83191.1 - 4.1e-07 29.3 0.0 6.1e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 mRNA stabilisation S1-P1_nuclease PF02265.16 ETS83192.1 - 7.2e-72 242.2 0.2 8.2e-72 242.1 0.2 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease DHHA2 PF02833.14 ETS83193.1 - 7.6e-37 126.7 0.1 1.3e-36 125.9 0.1 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 ETS83193.1 - 1.2e-10 41.5 0.1 2e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 DHH family FSA_C PF10479.9 ETS83195.1 - 2.1 6.4 16.4 2.8 6.0 16.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Zn_clus PF00172.18 ETS83196.1 - 7.3e-06 26.0 10.2 1.3e-05 25.2 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS83196.1 - 2.6e-05 23.4 0.1 6.1e-05 22.2 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain AFG1_ATPase PF03969.16 ETS83197.1 - 1.4e-98 330.1 0.0 3.6e-94 315.6 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 ETS83197.1 - 6.7e-05 23.3 2.2 0.03 14.7 0.0 3.5 3 1 1 4 4 4 1 AAA ATPase domain Bac_DnaA PF00308.18 ETS83197.1 - 0.00027 20.9 0.3 0.34 10.7 0.1 2.4 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_14 PF13173.6 ETS83197.1 - 0.002 18.2 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ETS83197.1 - 0.004 17.4 0.0 0.026 14.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 ETS83197.1 - 0.0087 16.5 0.0 0.03 14.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ETS83197.1 - 0.022 15.2 0.2 0.22 11.9 0.0 2.5 2 1 1 3 3 3 0 RNA helicase TsaE PF02367.17 ETS83197.1 - 0.027 14.5 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 ETS83197.1 - 0.031 14.3 0.0 0.078 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 ETS83197.1 - 0.043 13.7 0.0 0.14 12.1 0.0 2.0 1 1 0 1 1 1 0 NACHT domain ParB PF08775.10 ETS83197.1 - 0.074 13.5 0.4 1.4 9.4 0.1 2.7 3 0 0 3 3 3 0 ParB family ATPase_2 PF01637.18 ETS83197.1 - 0.082 12.8 0.0 0.54 10.1 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Mrx7 PF10906.8 ETS83197.1 - 0.13 12.6 0.2 0.37 11.1 0.2 1.8 1 0 0 1 1 1 0 MIOREX complex component 7 Dcc1 PF09724.9 ETS83198.1 - 1e-08 34.9 0.0 1.2e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 DUF5550 PF17704.1 ETS83198.1 - 0.007 16.5 0.0 0.0096 16.0 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5550) RhoGEF PF00621.20 ETS83199.1 - 1.1e-23 84.5 0.2 2.5e-23 83.2 0.0 1.8 2 0 0 2 2 2 1 RhoGEF domain Nod1 PF17114.5 ETS83199.1 - 0.015 15.4 0.0 0.05 13.8 0.0 1.9 2 0 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 DUF3507 PF12015.8 ETS83199.1 - 0.088 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) Fib_alpha PF08702.10 ETS83199.1 - 1.8 8.8 17.9 0.6 10.3 2.3 3.8 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family BRD4_CDT PF17105.5 ETS83199.1 - 4.3 7.0 5.9 4.2 7.1 0.1 2.7 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 IBN_N PF03810.19 ETS83200.1 - 2.7e-09 36.8 0.1 1.2e-08 34.7 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 ETS83200.1 - 5.8e-06 26.4 0.1 0.0031 17.6 0.0 4.0 4 0 0 4 4 4 1 Exportin 1-like protein CAS_CSE1 PF03378.15 ETS83200.1 - 0.0057 15.2 0.0 0.071 11.6 0.0 2.2 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus HORMA PF02301.18 ETS83201.1 - 4.2e-10 39.6 0.0 5.4e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 HORMA domain PI31_Prot_N PF11566.8 ETS83202.1 - 4.4e-61 205.4 0.0 5.4e-61 205.1 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 ETS83202.1 - 1.8e-14 54.6 14.8 1.8e-14 54.6 14.8 2.9 3 1 0 3 3 3 1 PI31 proteasome regulator Acetyltransf_7 PF13508.7 ETS83204.1 - 1.6e-05 25.3 0.0 3.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS83204.1 - 0.00074 19.7 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ETS83204.1 - 0.0075 16.3 0.3 0.038 14.1 0.1 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 ETS83204.1 - 0.043 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Cpn60_TCP1 PF00118.24 ETS83205.1 - 6.8e-153 509.8 12.0 7.7e-153 509.7 12.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ProRS-C_1 PF09180.11 ETS83206.1 - 3.2e-22 78.5 0.3 7.7e-22 77.3 0.3 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 ETS83206.1 - 1.9e-20 73.6 0.0 4.3e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ETS83206.1 - 1.9e-18 66.4 0.0 6.6e-18 64.6 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain RRP14 PF15459.6 ETS83206.1 - 1.8 9.2 10.1 1.4 9.6 7.0 2.4 3 0 0 3 3 3 0 60S ribosome biogenesis protein Rrp14 Terminase_4 PF05119.12 ETS83206.1 - 4.7 7.7 6.7 27 5.3 2.6 3.4 3 0 0 3 3 3 0 Phage terminase, small subunit Glyco_hydro_61 PF03443.14 ETS83207.1 - 7.4e-54 182.8 0.0 1.2e-53 182.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cpn10 PF00166.21 ETS83208.1 - 1.4e-25 89.2 0.0 1.5e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase PF00069.25 ETS83209.1 - 4.8e-49 167.1 0.0 1.9e-47 161.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS83209.1 - 2.7e-22 79.3 0.0 5.1e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ETS83209.1 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ETS83209.1 - 0.031 13.2 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF2781 PF10914.8 ETS83209.1 - 0.24 11.8 0.0 0.37 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) RR_TM4-6 PF06459.12 ETS83209.1 - 6.4 6.5 8.0 14 5.4 8.0 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NAD_binding_4 PF07993.12 ETS83210.1 - 2.2e-32 112.3 0.0 3.7e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 ETS83210.1 - 4e-21 75.1 0.0 5.9e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 ETS83210.1 - 1.7e-13 50.6 0.0 3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 ETS83210.1 - 0.00013 22.2 0.1 0.00048 20.4 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 ETS83210.1 - 0.0009 18.4 0.0 0.052 12.6 0.0 2.6 2 0 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ETS83210.1 - 0.019 14.3 0.0 0.072 12.5 0.0 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 ETS83210.1 - 0.17 12.3 0.0 0.89 10.0 0.0 2.2 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain DUF5450 PF17529.2 ETS83210.1 - 0.19 11.8 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5450) FAD_binding_3 PF01494.19 ETS83211.1 - 3.2e-12 46.4 0.5 2.4e-11 43.5 0.5 2.0 1 1 0 1 1 1 1 FAD binding domain Cupin_2 PF07883.11 ETS83212.1 - 1.5e-16 59.9 0.1 2.1e-14 52.9 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 ETS83212.1 - 0.00047 19.8 0.1 0.64 9.6 0.0 2.2 2 0 0 2 2 2 2 Cupin DMSP_lyase PF16867.5 ETS83212.1 - 0.044 13.4 0.4 0.061 13.0 0.4 1.4 1 1 0 1 1 1 0 Dimethlysulfonioproprionate lyase AraC_binding PF02311.19 ETS83212.1 - 0.056 13.4 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain MFS_1 PF07690.16 ETS83213.1 - 5e-25 88.2 43.3 4.1e-18 65.4 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS83213.1 - 1.4e-19 70.3 24.6 9.6e-19 67.6 24.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Phage_holin_3_2 PF04550.12 ETS83213.1 - 6.2 7.4 6.5 1.3 9.6 2.5 2.0 2 0 0 2 2 2 0 Phage holin family 2 Ribonuc_L-PSP PF01042.21 ETS83214.1 - 1.3e-18 67.1 0.0 1.8e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP p450 PF00067.22 ETS83215.1 - 3e-34 118.5 0.2 3.5e-34 118.3 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 ETS83216.1 - 3.6e-13 49.1 0.2 3.6e-13 49.1 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS83216.1 - 2e-09 37.4 5.9 4.9e-09 36.2 5.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 ETS83216.1 - 0.16 10.4 0.1 0.25 9.8 0.1 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B G_glu_transpept PF01019.21 ETS83217.1 - 9.2e-134 447.0 0.0 1.1e-133 446.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Transferase PF02458.15 ETS83218.1 - 2.4e-18 66.0 0.0 5.9e-13 48.3 0.0 2.1 2 0 0 2 2 2 2 Transferase family Glyco_hydro_79C PF16862.5 ETS83219.1 - 2e-13 51.1 0.2 4.2e-13 50.1 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_79C PF16862.5 ETS83220.1 - 4.7e-21 75.6 0.3 2.5e-20 73.3 0.1 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain MFS_1 PF07690.16 ETS83221.1 - 5.1e-41 140.8 23.8 5.1e-41 140.8 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS83221.1 - 2.4e-09 36.6 6.0 2.4e-09 36.6 6.0 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 ETS83221.1 - 7.5 4.7 10.0 0.03 12.6 0.3 2.0 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.19 ETS83222.1 - 1.6e-19 70.4 0.0 2.5e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 ETS83222.1 - 0.00012 21.2 0.0 0.0008 18.5 0.0 2.0 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 ETS83222.1 - 0.00096 18.8 2.1 0.0018 17.9 2.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS83222.1 - 0.0048 17.1 0.2 0.0048 17.1 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS83222.1 - 0.081 12.9 2.4 1.4 8.9 0.3 2.9 3 1 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ETS83222.1 - 0.2 10.9 2.7 0.43 9.8 2.7 1.7 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ETS83222.1 - 0.4 9.5 3.9 1.4 7.7 1.4 2.2 1 1 1 2 2 2 0 Tryptophan halogenase SNF2_N PF00176.23 ETS83223.1 - 2.1e-73 247.1 0.2 2.9e-73 246.6 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 ETS83223.1 - 7.1e-18 64.3 0.0 1.6e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 ETS83223.1 - 1.3e-15 57.6 0.0 3.9e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 ETS83223.1 - 9.2e-11 41.9 5.4 2e-10 40.9 5.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ETS83223.1 - 8.4e-09 35.1 6.3 1.7e-08 34.1 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS83223.1 - 1.6e-06 27.9 3.9 1.6e-06 27.9 3.9 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ETS83223.1 - 1.6e-06 27.9 4.9 3e-06 27.1 4.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ETS83223.1 - 3e-06 27.2 4.6 7e-06 26.0 4.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 ETS83223.1 - 3.2e-06 27.3 2.7 7.1e-06 26.2 2.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain ResIII PF04851.15 ETS83223.1 - 5.1e-06 26.6 0.0 1.2e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 ETS83223.1 - 1.7e-05 24.6 6.6 3.2e-05 23.7 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ETS83223.1 - 5e-05 23.1 5.7 0.00063 19.6 6.0 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 ETS83223.1 - 0.00011 21.9 4.5 0.00033 20.3 4.5 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 ETS83223.1 - 0.0047 16.9 1.7 0.0096 15.9 1.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 ETS83223.1 - 0.012 15.5 2.8 0.033 14.0 2.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 ETS83223.1 - 0.026 14.7 6.3 0.05 13.8 6.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 ETS83223.1 - 0.029 14.5 1.9 0.07 13.3 1.9 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 AAA_14 PF13173.6 ETS83223.1 - 0.036 14.1 0.1 8.4 6.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain NERD PF08378.11 ETS83223.1 - 0.048 14.1 0.1 0.17 12.4 0.1 1.9 1 0 0 1 1 1 0 Nuclease-related domain zf-Di19 PF05605.12 ETS83223.1 - 0.11 12.8 1.5 0.71 10.2 0.0 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.6 ETS83223.1 - 0.14 12.0 3.8 0.25 11.2 3.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 ETS83223.1 - 0.45 10.4 2.0 1.3 8.9 2.0 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zinc-ribbons_6 PF07191.12 ETS83223.1 - 1.7 8.6 3.9 3.3 7.7 3.9 1.4 1 0 0 1 1 1 0 zinc-ribbons Prok-RING_1 PF14446.6 ETS83223.1 - 3.3 7.7 4.8 15 5.6 1.7 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 CDO_I PF05995.12 ETS83224.1 - 4.6e-43 146.5 0.0 5.8e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 ETS83224.1 - 0.0028 17.1 0.2 0.0047 16.4 0.2 1.5 1 1 0 1 1 1 1 PCO_ADO DEC1 PF15859.5 ETS83224.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Deleted in esophageal cancer 1 family betaPIX_CC PF16523.5 ETS83225.1 - 0.022 14.6 0.1 0.046 13.6 0.1 1.5 1 0 0 1 1 1 0 betaPIX coiled coil GAS PF13851.6 ETS83225.1 - 0.33 10.3 4.2 0.067 12.5 0.6 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Septin PF00735.18 ETS83226.1 - 2.2e-120 401.2 0.2 2.2e-120 401.2 0.2 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 ETS83226.1 - 2.2e-08 34.2 1.1 5.6e-08 32.9 0.0 2.2 3 0 0 3 3 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ETS83226.1 - 8.6e-06 25.4 1.1 0.00041 19.9 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ETS83226.1 - 9.7e-05 22.3 2.9 0.0027 17.6 0.8 3.4 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 ETS83226.1 - 0.00025 21.5 2.8 0.026 15.0 0.0 3.0 3 0 0 3 3 3 1 ABC transporter AIG1 PF04548.16 ETS83226.1 - 0.00085 18.7 1.4 0.0024 17.2 0.0 2.3 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 ETS83226.1 - 0.0018 18.5 0.0 0.0041 17.3 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 ETS83226.1 - 0.002 18.6 0.1 0.0065 16.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS83226.1 - 0.0031 17.8 0.4 0.023 15.0 0.0 2.6 2 2 0 2 2 2 1 AAA domain Ras PF00071.22 ETS83226.1 - 0.0083 15.7 0.2 0.051 13.2 0.0 2.3 2 0 0 2 2 2 1 Ras family AAA_29 PF13555.6 ETS83226.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 ETS83226.1 - 0.044 13.8 7.2 1 9.4 0.0 4.0 4 1 0 4 4 3 0 Dynamin family FtsK_SpoIIIE PF01580.18 ETS83226.1 - 0.062 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 ETS83226.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 ETS83226.1 - 0.1 12.3 2.4 4.3 7.0 0.0 3.1 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 ETS83226.1 - 0.11 12.9 0.6 0.72 10.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 ETS83226.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TSNAXIP1_N PF15739.5 ETS83226.1 - 0.59 10.5 13.2 4.2 7.8 0.0 3.2 3 0 0 3 3 3 0 Translin-associated factor X-interacting N-terminus Exonuc_VII_L PF02601.15 ETS83226.1 - 1.4 8.4 7.5 2.4 7.7 7.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Strep_SA_rep PF06696.11 ETS83226.1 - 4.4 7.4 6.3 2 8.5 2.9 2.1 1 1 1 2 2 2 0 Streptococcal surface antigen repeat DUF87 PF01935.17 ETS83226.1 - 4.8 7.2 6.7 5.5 7.0 0.0 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain Atg14 PF10186.9 ETS83226.1 - 6.8 5.7 8.8 11 5.0 8.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 S4 PF01479.25 ETS83227.1 - 9.3e-14 50.9 0.1 1.1e-12 47.4 0.0 2.5 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.6 ETS83227.1 - 0.038 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 S4 domain RNA_pol_Rpb1_6 PF04992.14 ETS83227.1 - 0.092 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 SurA_N_3 PF13624.6 ETS83227.1 - 0.18 11.6 1.4 0.38 10.5 0.8 1.9 2 0 0 2 2 2 0 SurA N-terminal domain SKA1 PF07160.12 ETS83227.1 - 0.23 11.3 4.5 0.17 11.7 2.7 1.5 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Pkinase PF00069.25 ETS83228.1 - 2.7e-07 30.2 0.0 4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS83228.1 - 1.2e-05 24.8 0.0 0.00014 21.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ETS83229.1 - 8e-45 153.3 0.0 1.3e-44 152.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS83229.1 - 6e-25 88.0 0.0 1.2e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ETS83229.1 - 0.069 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fungal_trans_2 PF11951.8 ETS83230.1 - 1.4e-09 37.3 0.4 8.3e-09 34.7 0.6 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 ETS83231.1 - 2.6e-112 376.0 22.2 5.8e-112 374.8 22.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS83231.1 - 4.3e-25 88.4 45.2 1.3e-19 70.3 28.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily La PF05383.17 ETS83232.1 - 4.4e-20 71.5 0.0 7.1e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 ETS83232.1 - 6.2e-08 32.4 0.2 1.2e-07 31.4 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_61 PF03443.14 ETS83233.1 - 2.9e-41 141.7 0.0 3.5e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short PF00106.25 ETS83234.1 - 4.3e-26 91.6 2.8 4.9e-26 91.4 2.4 1.3 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 ETS83234.1 - 1e-05 25.1 1.3 1.9e-05 24.2 1.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ETS83234.1 - 2.2e-05 24.4 2.6 3.7e-05 23.7 2.6 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ETS83234.1 - 0.00044 20.2 8.9 0.0013 18.7 8.9 2.0 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ETS83234.1 - 0.0012 18.1 3.2 0.01 15.0 0.9 2.2 1 1 0 2 2 2 1 Male sterility protein NmrA PF05368.13 ETS83234.1 - 0.0062 16.1 2.0 0.01 15.4 2.0 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 ETS83234.1 - 0.076 12.4 1.1 0.14 11.5 0.7 1.9 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase NIBRIN_BRCT_II PF16508.5 ETS83234.1 - 0.15 12.4 0.9 0.32 11.3 0.4 1.8 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein MFS_1 PF07690.16 ETS83235.1 - 1.7e-40 139.0 24.0 1.7e-40 139.0 24.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS83235.1 - 6.8e-12 45.0 6.2 6.8e-12 45.0 6.2 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ETS83235.1 - 0.00013 20.5 2.3 0.0002 19.9 2.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 ETS83235.1 - 0.018 13.4 1.0 0.037 12.4 1.0 1.5 1 1 0 1 1 1 0 Transmembrane secretion effector Hce2 PF14856.6 ETS83236.1 - 4.9e-06 26.8 0.0 1.5e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Pathogen effector; putative necrosis-inducing factor Fungal_trans PF04082.18 ETS83237.1 - 4.6e-44 150.4 0.0 8.9e-44 149.5 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS83237.1 - 1.1e-08 35.0 6.7 2.4e-08 34.0 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.29 ETS83237.1 - 0.2 11.6 3.1 0.49 10.3 3.1 1.7 1 0 0 1 1 1 0 PHD-finger Fungal_trans PF04082.18 ETS83238.1 - 2.2e-31 108.9 0.0 9.1e-31 106.9 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS83238.1 - 5.7e-09 35.9 7.6 9.7e-09 35.2 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GREB1 PF15782.5 ETS83238.1 - 0.065 10.4 1.9 0.098 9.8 1.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4551 PF15087.6 ETS83238.1 - 7.2 5.3 6.0 2.5 6.8 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) Ank_2 PF12796.7 ETS83239.1 - 9.6e-64 212.0 16.5 1.2e-09 38.7 0.0 12.5 6 1 6 15 15 14 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS83239.1 - 1.8e-63 210.1 11.1 3.6e-06 27.4 0.0 17.5 12 3 7 19 19 19 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS83239.1 - 2.3e-38 125.8 19.9 0.046 14.3 0.0 21.9 27 0 0 27 27 24 8 Ankyrin repeat Ank PF00023.30 ETS83239.1 - 9.8e-33 111.2 31.7 0.0071 16.7 0.0 19.5 18 4 1 19 19 18 9 Ankyrin repeat Ank_5 PF13857.6 ETS83239.1 - 4.4e-21 74.7 34.9 0.0017 18.6 0.0 17.6 13 6 8 22 22 22 6 Ankyrin repeats (many copies) Helo_like_N PF17111.5 ETS83239.1 - 1.2e-08 34.5 0.7 2.3e-08 33.7 0.7 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NACHT PF05729.12 ETS83239.1 - 2.7e-07 30.6 0.0 6.9e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 ETS83239.1 - 0.00096 19.6 0.1 0.013 15.9 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS83239.1 - 0.0014 18.9 0.0 0.0056 17.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 ETS83239.1 - 0.057 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 ETS83239.1 - 0.089 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 ETS83239.1 - 0.16 12.4 0.0 0.51 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF5132 PF17195.4 ETS83239.1 - 0.82 9.8 3.4 0.73 10.0 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Tannase PF07519.11 ETS83240.1 - 4.1e-81 273.3 5.0 5.6e-81 272.8 5.0 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase MFS_1 PF07690.16 ETS83241.1 - 4.3e-46 157.5 32.7 4.3e-46 157.5 32.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS83241.1 - 4.5e-15 55.5 9.2 4.5e-15 55.5 9.2 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ETS83241.1 - 2.8e-05 22.7 1.4 4.8e-05 22.0 1.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3040 PF11239.8 ETS83241.1 - 0.18 12.1 0.1 0.18 12.1 0.1 4.5 4 2 2 6 6 6 0 Protein of unknown function (DUF3040) Draxin PF15550.6 ETS83241.1 - 0.26 11.1 0.4 0.4 10.5 0.4 1.2 1 0 0 1 1 1 0 Draxin Ank_5 PF13857.6 ETS83242.1 - 4.6e-06 26.8 0.0 0.0016 18.7 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS83242.1 - 5e-06 26.4 0.0 0.064 13.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 ETS83242.1 - 1.2e-05 25.8 0.0 2.1e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ETS83242.1 - 0.00018 21.8 0.0 0.41 11.2 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 ETS83242.1 - 0.00067 20.2 0.0 0.0015 19.1 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) BAT PF15915.5 ETS83242.1 - 0.012 15.5 0.1 0.015 15.2 0.1 1.1 1 0 0 1 1 1 0 GAF and HTH_10 associated domain Sacchrp_dh_NADP PF03435.18 ETS83242.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ETS83243.1 - 3.8e-26 92.0 0.0 3.2e-25 89.0 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS83243.1 - 8e-16 58.3 0.0 2.3e-15 56.9 0.0 1.8 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ETS83243.1 - 6.9e-11 41.7 0.0 2e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ETS83243.1 - 1.7e-07 31.3 0.0 2.6e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ETS83243.1 - 2.1e-07 30.3 0.0 6.9e-07 28.6 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ETS83243.1 - 1.4e-06 27.7 0.0 1.4e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 ETS83243.1 - 4e-06 26.2 0.0 1.8e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 ETS83243.1 - 0.0021 17.5 0.0 0.0067 15.9 0.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ETS83243.1 - 0.0023 17.9 0.1 0.04 13.8 0.1 2.3 1 1 0 1 1 1 1 KR domain Binary_toxB PF03495.14 ETS83243.1 - 0.083 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain ILVD_EDD PF00920.21 ETS83244.1 - 1.2e-183 611.4 0.0 1.5e-183 611.2 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family NmrA PF05368.13 ETS83245.1 - 2.9e-35 121.9 0.0 4.1e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS83245.1 - 1.1e-10 41.7 0.0 1.4e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS83245.1 - 8.3e-06 25.4 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS83245.1 - 0.023 13.7 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 ETS83245.1 - 0.084 13.5 0.1 0.33 11.6 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 ETS83245.1 - 0.099 12.6 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 ETS83245.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase bZIP_1 PF00170.21 ETS83246.1 - 0.00011 22.2 5.7 0.00024 21.2 5.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor Abhydrolase_1 PF00561.20 ETS83247.1 - 1.1e-17 64.5 0.3 1.2e-16 61.1 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS83247.1 - 1.4e-12 48.7 0.1 1.9e-12 48.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS83247.1 - 6.5e-08 32.1 0.0 7.3e-07 28.7 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 ETS83247.1 - 3.4e-05 23.5 0.0 0.0032 17.0 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 ETS83247.1 - 0.00011 21.7 0.0 0.0018 17.8 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family PGAP1 PF07819.13 ETS83247.1 - 0.019 14.7 0.0 0.048 13.4 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Thioesterase PF00975.20 ETS83247.1 - 0.038 14.1 0.0 0.061 13.4 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain FSH1 PF03959.13 ETS83247.1 - 0.062 13.0 0.2 0.58 9.8 0.2 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 ETS83247.1 - 0.11 12.2 0.0 3.9 7.2 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 ETS83248.1 - 1.9e-25 90.0 0.0 3.4e-24 85.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS83248.1 - 1.9e-16 61.3 0.0 2.6e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 ETS83248.1 - 4.2e-05 22.4 0.0 6.6e-05 21.8 0.0 1.5 1 1 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.8 ETS83248.1 - 0.00011 21.6 0.0 0.00052 19.4 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 ETS83248.1 - 0.0046 16.7 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Pax2_C PF12403.8 ETS83248.1 - 0.018 15.1 0.2 0.046 13.8 0.1 1.7 2 0 0 2 2 2 0 Paired-box protein 2 C terminal Ser_hydrolase PF06821.13 ETS83248.1 - 0.023 14.5 0.0 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase DUF1774 PF08611.10 ETS83249.1 - 5e-37 126.1 3.5 5e-37 126.1 3.5 3.3 4 0 0 4 4 4 1 Fungal protein of unknown function (DUF1774) ACPS PF01648.20 ETS83250.1 - 3.2e-08 33.7 0.2 9.8e-08 32.1 0.2 2.0 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 ETS83250.1 - 0.0028 17.7 1.3 0.78 9.9 0.1 2.4 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase N-terminal domain SPRY PF00622.28 ETS83251.1 - 0.0086 16.2 0.0 0.078 13.1 0.0 2.4 3 0 0 3 3 3 1 SPRY domain DUF1499 PF07386.11 ETS83251.1 - 0.034 14.7 0.0 0.075 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) SMC_Nse1 PF07574.13 ETS83253.1 - 5.4e-65 218.9 0.1 7.7e-65 218.4 0.1 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 ETS83253.1 - 1.3e-15 57.4 10.1 2.3e-15 56.6 10.1 1.4 1 0 0 1 1 1 1 RING-like domain HTH_Crp_2 PF13545.6 ETS83253.1 - 0.03 14.3 0.0 0.37 10.8 0.0 2.3 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain CwsA PF10814.8 ETS83253.1 - 0.13 12.5 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA zf-RING_2 PF13639.6 ETS83253.1 - 0.66 10.4 7.8 1.2 9.5 7.8 1.5 1 0 0 1 1 1 0 Ring finger domain C1_1 PF00130.22 ETS83253.1 - 0.76 9.7 8.7 0.41 10.6 3.7 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 ETS83253.1 - 1.1 9.5 6.0 3.9 7.8 6.1 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-ribbon_3 PF13248.6 ETS83253.1 - 2.5 7.7 4.4 7.9 6.0 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain PPP4R2 PF09184.11 ETS83254.1 - 1.7 8.2 14.0 2 8.0 14.0 1.2 1 0 0 1 1 1 0 PPP4R2 RXT2_N PF08595.11 ETS83254.1 - 1.9 8.5 8.1 3.5 7.6 8.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal LSM PF01423.22 ETS83256.1 - 2.2e-15 56.1 0.1 2.8e-15 55.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hairpins PF04877.12 ETS83256.1 - 0.3 10.7 6.4 0.38 10.4 6.4 1.1 1 0 0 1 1 1 0 HrpZ PPR_2 PF13041.6 ETS83257.1 - 1.8e-11 44.0 0.0 0.00057 20.0 0.0 7.4 7 2 2 9 9 9 2 PPR repeat family PPR_long PF17177.4 ETS83257.1 - 3.8e-08 32.9 0.1 0.0011 18.4 0.1 3.3 3 0 0 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 ETS83257.1 - 5.2e-06 26.4 0.0 0.087 12.9 0.0 4.5 4 0 0 4 4 4 2 Pentatricopeptide repeat domain MFS_1 PF07690.16 ETS83258.1 - 1e-29 103.6 38.1 1e-29 103.6 38.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Spc24 PF08286.11 ETS83259.1 - 1.9e-39 134.1 1.1 3.4e-37 126.9 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 DUF4164 PF13747.6 ETS83259.1 - 0.0033 17.7 9.5 0.0064 16.8 6.5 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4164) APG6_N PF17675.1 ETS83259.1 - 0.0056 17.2 6.2 0.008 16.7 6.2 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region FlgN PF05130.12 ETS83259.1 - 0.059 13.9 1.2 0.059 13.9 1.2 2.0 1 1 1 2 2 2 0 FlgN protein V_ATPase_I PF01496.19 ETS83259.1 - 0.076 10.9 0.5 0.077 10.9 0.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BAR_3 PF16746.5 ETS83259.1 - 0.095 12.4 2.8 0.75 9.5 2.9 1.9 1 1 0 1 1 1 0 BAR domain of APPL family Vps5 PF09325.10 ETS83259.1 - 0.096 12.2 6.4 0.17 11.4 5.4 1.7 1 1 1 2 2 2 0 Vps5 C terminal like Ax_dynein_light PF10211.9 ETS83259.1 - 0.21 11.5 3.7 1.2 9.1 2.1 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain DUF724 PF05266.14 ETS83259.1 - 0.23 11.3 3.3 0.4 10.5 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF4472 PF14739.6 ETS83259.1 - 0.27 12.0 5.3 0.22 12.3 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) ABC_tran_CTD PF16326.5 ETS83259.1 - 0.63 10.3 7.6 4.2 7.7 2.5 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF4554 PF15091.6 ETS83259.1 - 1.3 7.9 7.4 0.49 9.2 2.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4554) Ribosomal_L29 PF00831.23 ETS83259.1 - 3.6 7.6 6.4 4 7.5 1.1 3.0 3 1 0 3 3 3 0 Ribosomal L29 protein Fis1_TPR_C PF14853.6 ETS83260.1 - 1.2e-25 89.3 1.8 2.1e-25 88.5 1.8 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 ETS83260.1 - 3.8e-18 64.8 0.1 6.6e-18 64.1 0.1 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 ETS83260.1 - 0.0044 17.0 1.1 0.0092 16.0 1.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat zf-RING_2 PF13639.6 ETS83261.1 - 1.6e-14 53.9 16.1 6.1e-14 52.1 6.4 2.3 2 0 0 2 2 2 2 Ring finger domain zf-RING_11 PF17123.5 ETS83261.1 - 3.6e-10 39.4 3.1 3.6e-10 39.4 3.1 2.8 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 ETS83261.1 - 4.3e-10 39.3 8.7 9.6e-09 35.0 2.1 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ETS83261.1 - 5.1e-09 35.8 6.6 5.1e-09 35.8 6.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ETS83261.1 - 4e-07 30.2 5.4 4e-07 30.2 5.4 2.9 2 1 1 3 3 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ETS83261.1 - 1.8e-06 27.7 14.9 5.4e-06 26.2 6.1 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS83261.1 - 3.9e-06 26.8 0.6 3.9e-06 26.8 0.6 2.4 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 ETS83261.1 - 7.9e-06 25.7 2.9 7.9e-06 25.7 2.9 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ETS83261.1 - 3.9e-05 23.4 4.1 3.9e-05 23.4 4.1 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 HypA PF01155.19 ETS83261.1 - 0.0011 18.9 0.2 0.0011 18.9 0.2 2.0 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ANAPC11 PF12861.7 ETS83261.1 - 0.0017 18.4 1.7 0.0017 18.4 1.7 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_9 PF14369.6 ETS83261.1 - 0.0075 16.5 7.1 0.015 15.5 4.1 2.3 2 0 0 2 2 2 1 zinc-ribbon DUF1272 PF06906.11 ETS83261.1 - 0.014 15.5 7.6 0.16 12.1 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 ETS83261.1 - 0.058 13.2 11.1 0.088 12.6 3.3 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain A2L_zn_ribbon PF08792.10 ETS83261.1 - 0.12 12.1 2.7 0.32 10.8 2.7 1.6 1 0 0 1 1 1 0 A2L zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 ETS83261.1 - 0.13 12.3 3.9 4.4 7.3 0.1 2.6 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zinc-ribbons_6 PF07191.12 ETS83261.1 - 0.27 11.2 7.4 1.2 9.1 0.7 2.3 2 0 0 2 2 2 0 zinc-ribbons Prok-RING_1 PF14446.6 ETS83261.1 - 0.78 9.7 10.1 5 7.1 0.3 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 ETS83261.1 - 1.3 8.7 11.6 0.32 10.6 4.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 ETS83261.1 - 2.1 8.5 6.4 3.7 7.6 0.5 2.5 2 1 0 2 2 2 0 Double zinc ribbon RINGv PF12906.7 ETS83261.1 - 3.3 7.9 17.1 0.057 13.5 8.5 2.2 2 0 0 2 2 2 0 RING-variant domain Zn-ribbon_8 PF09723.10 ETS83261.1 - 3.4 7.9 6.5 1.3 9.2 0.5 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-P11 PF03854.14 ETS83261.1 - 5.8 6.7 11.1 0.035 13.7 2.3 1.8 2 0 0 2 2 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.6 ETS83261.1 - 6.5 7.0 12.9 5.5 7.2 1.5 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING TatD_DNase PF01026.21 ETS83263.1 - 2e-30 106.0 0.0 4.1e-30 105.0 0.0 1.5 1 1 0 1 1 1 1 TatD related DNase Fungal_trans PF04082.18 ETS83264.1 - 4.4e-25 88.2 0.4 6.3e-25 87.7 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS83264.1 - 1.8e-07 31.1 9.9 3.3e-07 30.3 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1100 PF06500.11 ETS83265.1 - 2.4e-07 29.9 0.0 4.5e-06 25.7 0.0 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Hydrolase_4 PF12146.8 ETS83265.1 - 0.013 14.8 0.0 0.28 10.4 0.0 2.7 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS83265.1 - 0.019 14.6 0.1 1.7 8.2 0.2 2.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.20 ETS83265.1 - 0.066 12.8 0.0 0.98 9.0 0.0 2.1 2 0 0 2 2 2 0 Putative esterase TAtT PF16811.5 ETS83265.1 - 0.16 11.3 1.5 0.27 10.5 1.5 1.2 1 0 0 1 1 1 0 TRAP transporter T-component GCK PF07802.11 ETS83266.1 - 0.1 13.0 0.2 0.19 12.2 0.2 1.4 1 0 0 1 1 1 0 GCK domain Pyridox_oxase_2 PF12766.7 ETS83267.1 - 8.8e-21 74.4 0.0 3.5e-19 69.3 0.0 2.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CPSase_L_D2 PF02786.17 ETS83268.1 - 6.1e-111 369.0 0.1 3.6e-83 278.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 ETS83268.1 - 3e-47 159.6 0.0 7.4e-47 158.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 ETS83268.1 - 3.5e-47 160.6 0.0 7.6e-47 159.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 ETS83268.1 - 2.4e-45 154.2 0.1 5.7e-45 153.0 0.1 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 ETS83268.1 - 5.4e-41 139.8 0.1 1.2e-40 138.7 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 ETS83268.1 - 8.1e-30 104.0 0.0 3.7e-29 101.8 0.0 2.2 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 ETS83268.1 - 4.6e-23 81.2 0.0 1.7e-22 79.4 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 ETS83268.1 - 1.8e-17 63.5 0.6 1.8e-07 30.9 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ETS83268.1 - 8.3e-16 58.0 0.0 1.2e-07 31.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 ETS83268.1 - 3.1e-10 39.9 0.0 0.00012 21.9 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 ETS83268.1 - 2e-05 24.7 0.2 0.18 11.8 0.0 2.9 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 ETS83268.1 - 2.4e-05 24.2 0.2 0.0041 16.9 0.2 2.5 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 ETS83268.1 - 0.00032 20.5 0.7 0.17 11.7 0.0 3.8 4 0 0 4 4 4 1 DJ-1/PfpI family hGDE_N PF14699.6 ETS83268.1 - 0.094 12.9 0.1 1 9.5 0.0 2.6 2 0 0 2 2 2 0 N-terminal domain from the human glycogen debranching enzyme PC-Esterase PF13839.6 ETS83268.1 - 0.18 11.5 0.0 6.8 6.3 0.0 2.2 2 0 0 2 2 2 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Ion_trans PF00520.31 ETS83269.1 - 3.8e-07 29.6 30.1 5.8e-07 29.0 30.1 1.2 1 0 0 1 1 1 1 Ion transport protein Nipped-B_C PF12830.7 ETS83270.1 - 7.8e-49 166.2 1.0 2.7e-46 157.9 0.5 3.5 2 1 0 2 2 2 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 ETS83270.1 - 1.7e-10 41.0 4.9 5.5e-09 36.2 0.9 3.4 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 ETS83270.1 - 2.2e-05 24.3 3.0 0.023 14.9 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 ETS83270.1 - 0.00019 21.5 0.2 0.019 15.0 0.1 2.9 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ETS83270.1 - 0.0055 15.3 0.1 0.041 12.4 0.1 2.3 2 1 0 2 2 2 1 Adaptin N terminal region TFIIS_C PF01096.18 ETS83271.1 - 7.3e-16 57.7 2.8 1e-15 57.3 2.8 1.2 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) EPF PF17181.4 ETS83271.1 - 0.024 14.6 1.2 0.039 14.0 1.2 1.3 1 0 0 1 1 1 0 Epidermal patterning factor proteins tRNA-synt_1f PF01921.18 ETS83271.1 - 0.036 13.0 0.4 0.044 12.7 0.4 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (K) HEAT_2 PF13646.6 ETS83272.1 - 2.1e-27 95.3 5.3 8.1e-14 51.8 0.1 3.5 2 2 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.16 ETS83272.1 - 9.7e-20 69.2 7.0 0.0059 17.2 0.0 6.5 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 ETS83272.1 - 9.7e-07 28.5 3.1 0.49 10.8 0.0 5.8 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 ETS83272.1 - 0.00011 22.7 8.3 0.56 10.8 0.0 5.5 4 1 2 6 6 6 2 HEAT-like repeat DnaG_DnaB_bind PF08278.11 ETS83272.1 - 0.037 14.6 2.3 7.7 7.1 0.2 2.4 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding Arm PF00514.23 ETS83272.1 - 0.11 12.6 2.8 18 5.6 0.0 3.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RuvA_C PF07499.13 ETS83272.1 - 2.2 8.8 6.3 12 6.4 0.0 3.8 4 0 0 4 4 4 0 RuvA, C-terminal domain PNP_phzG_C PF10590.9 ETS83273.1 - 7e-22 77.2 2.2 7e-22 77.2 2.2 2.4 2 1 1 3 3 3 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 ETS83273.1 - 4.8e-20 71.5 0.0 7.5e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 ETS83273.1 - 0.0032 18.1 0.1 0.017 15.7 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Asn_synthase PF00733.21 ETS83274.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.1 1 0 0 1 1 1 0 Asparagine synthase bZIP_1 PF00170.21 ETS83275.1 - 0.11 12.6 9.6 0.22 11.6 9.6 1.5 1 0 0 1 1 1 0 bZIP transcription factor NDT80_PhoG PF05224.12 ETS83276.1 - 7.5e-42 143.6 0.0 1.6e-41 142.6 0.0 1.5 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family ArfGap PF01412.18 ETS83277.1 - 1.2e-34 118.8 0.2 2.3e-34 118.0 0.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TIM21 PF08294.11 ETS83278.1 - 9.5e-46 155.3 0.0 1.2e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 ETS83278.1 - 9.1e-07 28.6 0.0 1.6e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 FAD-oxidase_C PF02913.19 ETS83278.1 - 0.03 14.0 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Bromodomain PF00439.25 ETS83279.1 - 2e-17 63.0 0.0 4.3e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain BTB PF00651.31 ETS83279.1 - 6.2e-06 26.4 0.0 1.4e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 ETS83280.1 - 5.4e-07 29.8 10.2 2e-05 24.8 3.5 4.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.26 ETS83280.1 - 1.4e-05 25.3 14.0 0.00046 20.5 4.5 3.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS83280.1 - 0.052 14.4 3.1 0.052 14.4 3.1 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ETS83280.1 - 0.054 13.8 0.4 0.054 13.8 0.4 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ETS83280.1 - 0.17 12.5 0.2 0.17 12.5 0.2 2.7 2 1 1 3 3 3 0 FOXP coiled-coil domain DUF2225 PF09986.9 ETS83280.1 - 0.42 10.3 0.7 0.86 9.3 0.7 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) ATPase PF06745.13 ETS83281.1 - 3.6e-07 29.8 0.0 6.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 KaiC RecA PF00154.21 ETS83281.1 - 2.3e-06 27.3 0.0 1.2e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 recA bacterial DNA recombination protein Rad51 PF08423.11 ETS83281.1 - 5.3e-06 25.9 0.0 1.4e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 ETS83281.1 - 8.5e-06 25.5 0.0 2.3e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ETS83281.1 - 3.7e-05 23.6 0.0 7.2e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ETS83281.1 - 0.0015 18.3 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DnaB_C PF03796.15 ETS83281.1 - 0.01 15.2 0.0 0.047 13.0 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA PF00004.29 ETS83281.1 - 0.071 13.5 0.0 0.15 12.5 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 ETS83281.1 - 0.18 11.6 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF676 PF05057.14 ETS83282.1 - 1.2e-41 142.7 0.0 2.4e-26 92.6 0.0 3.4 3 0 0 3 3 3 3 Putative serine esterase (DUF676) Lipase_3 PF01764.25 ETS83282.1 - 0.089 12.7 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) IBR PF01485.21 ETS83283.1 - 6.4e-12 45.5 45.8 1.7e-08 34.6 12.4 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain DUF2158 PF09926.9 ETS83283.1 - 0.14 11.9 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) DUF4611 PF15387.6 ETS83283.1 - 2.6 8.3 6.0 8.2 6.7 6.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Metallophos PF00149.28 ETS83285.1 - 5.3e-32 112.0 0.0 8.3e-23 82.0 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ETS83285.1 - 0.03 14.8 0.1 0.082 13.4 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Pterin_bind PF00809.22 ETS83286.1 - 3e-75 253.0 0.0 4.2e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 ETS83286.1 - 3.6e-36 124.1 0.0 1.4e-35 122.2 0.0 2.0 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.15 ETS83287.1 - 4.7e-50 170.8 0.1 7.1e-50 170.3 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 ETS83287.1 - 5.5e-06 25.7 0.5 8.2e-06 25.1 0.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ETS83287.1 - 9.6e-06 24.8 2.6 1.6e-05 24.1 2.6 1.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ETS83287.1 - 0.0015 17.8 0.1 0.0022 17.2 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DUF2680 PF10925.8 ETS83287.1 - 0.048 13.7 0.4 0.16 12.0 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2680) adh_short_C2 PF13561.6 ETS83288.1 - 4.5e-39 134.4 0.0 7.1e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS83288.1 - 1.4e-36 125.8 0.0 2.4e-36 125.1 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS83288.1 - 5.4e-13 49.2 0.2 2.3e-11 44.0 0.0 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 ETS83288.1 - 0.051 13.0 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MscL PF01741.18 ETS83289.1 - 2.6e-18 66.5 0.0 3.2e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL C1_1 PF00130.22 ETS83289.1 - 0.036 13.9 0.7 0.058 13.3 0.7 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SUR7 PF06687.12 ETS83290.1 - 1.4e-27 96.7 1.9 1.7e-27 96.4 1.9 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 ETS83290.1 - 1.4e-05 25.1 6.3 1.4e-05 25.1 6.3 1.7 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 MRAP PF15183.6 ETS83290.1 - 0.18 11.8 3.5 6.7 6.7 1.5 2.6 2 1 0 2 2 2 0 Melanocortin-2 receptor accessory protein family DUF4231 PF14015.6 ETS83290.1 - 5.1 7.6 6.4 16 6.0 2.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) LRR_1 PF00560.33 ETS83291.1 - 0.073 13.7 0.9 52 5.0 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 ETS83291.1 - 0.098 13.1 1.7 66 4.1 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) TraG-D_C PF12696.7 ETS83293.1 - 0.17 11.8 0.8 0.31 11.1 0.8 1.3 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Glyco_hydro_76 PF03663.14 ETS83294.1 - 2.8e-132 441.7 13.0 3.4e-132 441.4 13.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 ETS83294.1 - 0.00036 19.7 5.0 0.014 14.5 0.3 3.0 3 0 0 3 3 3 2 Glycosyl Hydrolase Family 88 Aminotran_1_2 PF00155.21 ETS83295.1 - 1.7e-60 205.1 0.0 2.1e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ETS83295.1 - 0.13 10.7 0.0 0.25 9.8 0.0 1.5 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.25 ETS83296.1 - 5.9e-28 98.0 0.0 8.5e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS83296.1 - 1.6e-09 37.4 0.0 1.9e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ETS83296.1 - 0.00035 20.0 0.2 0.00099 18.5 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ETS83296.1 - 0.021 14.8 2.1 0.021 14.8 2.1 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pro-kuma_activ PF09286.11 ETS83297.1 - 3.2e-47 160.4 0.0 5.4e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ETS83297.1 - 1.8e-05 24.2 0.0 3.1e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Subtilase family DUF3678 PF12435.8 ETS83297.1 - 0.16 11.3 0.5 0.31 10.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) TPR_1 PF00515.28 ETS83298.1 - 0.00012 21.8 5.3 0.51 10.2 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ETS83298.1 - 0.00082 19.3 7.1 0.43 10.8 0.3 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS83298.1 - 0.0068 16.9 3.6 0.038 14.5 3.6 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS83298.1 - 0.22 11.8 1.6 0.67 10.2 1.6 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Macoilin PF09726.9 ETS83299.1 - 5 5.5 4.6 6.5 5.2 4.6 1.1 1 0 0 1 1 1 0 Macoilin family DNA_topoisoIV PF00521.20 ETS83300.1 - 5.3e-120 401.2 2.4 2.6e-119 398.9 0.1 2.7 3 0 0 3 3 3 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 ETS83300.1 - 1.3e-49 167.7 2.6 4.7e-49 165.9 2.6 2.1 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 ETS83300.1 - 3.6e-24 85.2 2.1 8.3e-24 84.0 2.1 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 ETS83300.1 - 7e-13 49.1 0.0 2.6e-12 47.2 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 ETS83300.1 - 4.4e-06 26.9 0.0 2.1e-05 24.7 0.0 2.3 1 0 0 1 1 1 1 Toprim domain PI3_PI4_kinase PF00454.27 ETS83300.1 - 0.068 13.0 0.3 0.17 11.7 0.3 1.6 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase Reticulon PF02453.17 ETS83301.1 - 9.5e-36 123.1 4.5 1.5e-35 122.5 4.5 1.3 1 0 0 1 1 1 1 Reticulon RabGAP-TBC PF00566.18 ETS83302.1 - 4.5e-49 167.0 0.0 1.8e-48 165.0 0.0 2.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Prominin PF05478.11 ETS83302.1 - 0.002 16.2 1.9 0.0036 15.3 1.9 1.3 1 0 0 1 1 1 1 Prominin ADIP PF11559.8 ETS83302.1 - 0.0046 17.1 11.5 0.0046 17.1 11.5 4.4 3 2 1 4 4 4 1 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 ETS83302.1 - 2.5 8.1 12.3 0.11 12.5 4.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 ETS83302.1 - 5.1 7.0 10.5 1.6 8.7 2.8 2.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Occludin_ELL PF07303.13 ETS83302.1 - 10 6.9 14.7 16 6.3 2.1 4.4 2 1 2 4 4 4 0 Occludin homology domain SPX PF03105.19 ETS83303.1 - 5 6.9 12.8 12 5.7 12.8 1.9 1 1 0 1 1 1 0 SPX domain SnoaL PF07366.12 ETS83304.1 - 0.019 14.8 0.0 0.032 14.0 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Cys_Met_Meta_PP PF01053.20 ETS83305.1 - 1.2e-138 461.8 0.0 1.4e-138 461.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ETS83305.1 - 1.2e-06 27.8 0.0 8e-06 25.1 0.2 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 ETS83305.1 - 8.7e-06 24.5 0.3 2.9e-05 22.8 0.3 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 ETS83305.1 - 0.00058 19.3 0.3 0.0021 17.5 0.1 1.9 2 1 1 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 ETS83305.1 - 0.038 13.3 0.1 0.13 11.5 0.1 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase Pantoate_transf PF02548.15 ETS83305.1 - 0.11 11.9 0.6 0.32 10.3 0.2 1.9 2 0 0 2 2 2 0 Ketopantoate hydroxymethyltransferase GCP_N_terminal PF17681.1 ETS83306.1 - 5.7e-63 213.4 0.0 1e-62 212.6 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ETS83306.1 - 8.5e-59 199.5 4.6 8.5e-59 199.5 4.6 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Proteasome PF00227.26 ETS83307.1 - 9.2e-57 191.6 0.1 1.2e-56 191.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ETS83307.1 - 1.6e-12 46.9 0.0 3.6e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Fungal_trans_2 PF11951.8 ETS83308.1 - 8.8e-17 61.0 0.0 4.8e-09 35.5 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS83308.1 - 3e-08 33.6 12.0 5e-08 32.9 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_8 PF05148.15 ETS83309.1 - 4.8e-57 193.3 0.0 7.9e-55 186.1 0.0 2.6 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 ETS83309.1 - 8.2e-06 26.4 0.0 3.6e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS83309.1 - 0.00013 22.6 0.0 0.0097 16.6 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ETS83309.1 - 0.0006 19.8 0.2 0.0033 17.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS83309.1 - 0.0046 16.8 0.0 0.35 10.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain DUF4770 PF15994.5 ETS83309.1 - 1.8 8.8 4.2 3.8 7.7 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF5308 PF17233.2 ETS83309.1 - 5.7 7.1 14.6 0.12 12.6 0.3 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5308) Asp_protease PF09668.10 ETS83310.1 - 2e-54 182.6 0.3 3.6e-54 181.8 0.3 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 ETS83310.1 - 1.6e-21 76.7 0.2 4.1e-21 75.3 0.2 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 ETS83310.1 - 1.7e-12 47.8 0.2 6.7e-12 45.9 0.1 2.2 2 0 0 2 2 2 1 Aspartyl protease UBA PF00627.31 ETS83310.1 - 1.8e-07 30.9 0.0 4.9e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain RVP PF00077.20 ETS83310.1 - 4.9e-06 26.8 0.3 1.5e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease ubiquitin PF00240.23 ETS83310.1 - 3.1e-05 23.7 0.0 6.8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.11 ETS83310.1 - 8.1e-05 22.4 0.0 0.00019 21.2 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Fungal_trans PF04082.18 ETS83311.1 - 9.6e-36 123.2 0.0 9.6e-36 123.2 0.0 1.6 2 0 0 2 2 1 1 Fungal specific transcription factor domain EOS1 PF12326.8 ETS83311.1 - 0.052 13.5 1.7 0.12 12.3 1.7 1.5 1 0 0 1 1 1 0 N-glycosylation protein DUF3810 PF12725.7 ETS83311.1 - 0.06 12.7 0.5 0.099 12.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Allexi_40kDa PF05549.11 ETS83311.1 - 0.16 11.4 3.9 0.36 10.3 3.9 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein MCU PF04678.13 ETS83311.1 - 0.25 11.4 7.0 0.57 10.3 7.0 1.6 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Anoctamin PF04547.12 ETS83311.1 - 0.41 9.4 6.4 0.58 8.9 6.4 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF2052 PF09747.9 ETS83311.1 - 0.42 10.7 13.8 1.1 9.3 13.8 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Peptidase_S49_N PF08496.10 ETS83311.1 - 0.66 10.0 8.0 1.5 8.9 8.0 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1266 PF06889.11 ETS83311.1 - 0.82 9.7 7.3 1.7 8.7 7.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Dna2 PF08696.11 ETS83311.1 - 1.8 8.3 6.6 3.1 7.5 6.6 1.3 1 0 0 1 1 1 0 DNA replication factor Dna2 FUSC PF04632.12 ETS83311.1 - 2.2 6.7 5.7 3.9 5.9 5.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Plasmodium_Vir PF05795.11 ETS83311.1 - 2.4 7.5 4.4 4.2 6.7 4.4 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SRP-alpha_N PF04086.13 ETS83311.1 - 3.4 7.5 16.1 0.16 11.8 10.1 1.7 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal TMEM51 PF15345.6 ETS83311.1 - 3.6 7.3 10.3 8.4 6.2 10.3 1.6 1 0 0 1 1 1 0 Transmembrane protein 51 F-protein PF00469.20 ETS83311.1 - 5.5 6.5 11.5 14 5.2 11.5 1.7 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF4446 PF14584.6 ETS83311.1 - 6.4 6.8 6.2 13 5.8 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DDHD PF02862.17 ETS83311.1 - 6.9 6.8 13.3 0.2 11.8 5.1 2.3 3 0 0 3 3 3 0 DDHD domain ALMT PF11744.8 ETS83311.1 - 8.7 5.0 6.7 14 4.4 6.7 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4834 PF16118.5 ETS83311.1 - 9.1 7.3 17.5 0.29 12.1 8.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Kei1 PF08552.11 ETS83311.1 - 9.4 6.1 8.1 0.22 11.4 1.5 1.6 2 0 0 2 2 1 0 Inositolphosphorylceramide synthase subunit Kei1 PigN PF04987.14 ETS83313.1 - 5.7e-166 552.9 32.3 5.7e-166 552.9 32.3 1.9 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 ETS83313.1 - 5.2e-10 39.4 3.2 2.5e-08 33.9 3.2 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ETS83313.1 - 2.4e-09 37.0 0.3 2.4e-09 37.0 0.3 2.0 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 ETS83313.1 - 6.7e-05 22.4 0.1 0.00012 21.6 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Csm1 PF12539.8 ETS83314.1 - 2e-33 114.9 0.5 4.3e-33 113.8 0.5 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Cep57_CLD PF14073.6 ETS83314.1 - 0.0014 18.6 7.0 0.0024 17.9 7.0 1.4 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 DUF5094 PF17015.5 ETS83314.1 - 0.0083 16.2 3.0 0.05 13.7 3.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF5094) EzrA PF06160.12 ETS83314.1 - 0.014 13.6 3.1 0.02 13.1 3.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Atg14 PF10186.9 ETS83314.1 - 0.025 13.7 3.8 0.034 13.3 3.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Rootletin PF15035.6 ETS83314.1 - 0.027 14.5 8.6 0.054 13.5 8.6 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion MPS2 PF17060.5 ETS83314.1 - 0.057 12.7 3.2 0.13 11.5 3.2 1.4 1 1 0 1 1 1 0 Monopolar spindle protein 2 Spc7 PF08317.11 ETS83314.1 - 0.063 12.1 6.4 0.12 11.2 6.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 ETS83314.1 - 0.37 10.1 11.0 0.73 9.1 11.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TACC_C PF05010.14 ETS83314.1 - 0.48 10.2 9.6 1.2 8.9 9.6 1.7 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal KxDL PF10241.9 ETS83314.1 - 0.67 10.3 4.3 1.8 8.9 4.3 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein FUSC PF04632.12 ETS83314.1 - 1.5 7.3 7.3 2.2 6.7 7.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family YabA PF06156.13 ETS83314.1 - 4.1 8.1 5.8 4.8 7.9 3.5 2.1 1 1 1 2 2 2 0 Initiation control protein YabA TMF_DNA_bd PF12329.8 ETS83314.1 - 4.7 7.3 13.0 1.3 9.1 7.1 2.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding UPF0449 PF15136.6 ETS83314.1 - 4.9 7.7 7.0 6.3 7.3 4.1 2.4 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 TEX13 PF15186.6 ETS83314.1 - 5.1 6.8 7.5 9.9 5.8 7.5 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF2203 PF09969.9 ETS83314.1 - 5.4 7.8 9.1 3.3 8.4 4.1 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) ATG16 PF08614.11 ETS83314.1 - 9 6.5 20.0 0.76 10.0 14.8 1.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) AAA PF00004.29 ETS83315.1 - 1.5e-37 128.9 0.0 2.8e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ETS83315.1 - 9.4e-10 38.2 0.0 1.9e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 ETS83315.1 - 7.2e-06 26.5 0.2 0.00045 20.7 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 ETS83315.1 - 8e-06 25.9 0.0 1.9e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ETS83315.1 - 1.1e-05 25.3 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ETS83315.1 - 4.1e-05 23.6 0.1 0.0004 20.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ETS83315.1 - 7e-05 23.1 0.1 0.0051 17.1 0.0 2.8 1 1 2 3 3 3 1 AAA domain AAA_2 PF07724.14 ETS83315.1 - 0.00012 22.2 0.0 0.00028 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 ETS83315.1 - 0.00087 19.1 0.0 0.0023 17.7 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein TniB PF05621.11 ETS83315.1 - 0.0016 17.9 0.0 1.2 8.6 0.0 2.4 1 1 0 2 2 2 2 Bacterial TniB protein Mg_chelatase PF01078.21 ETS83315.1 - 0.0017 17.8 0.1 0.0038 16.6 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 ETS83315.1 - 0.0026 17.9 0.0 0.005 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ETS83315.1 - 0.0046 17.3 0.0 0.014 15.7 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_25 PF13481.6 ETS83315.1 - 0.0083 15.7 0.1 0.072 12.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ETS83315.1 - 0.0084 16.0 0.0 0.02 14.8 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 ETS83315.1 - 0.016 15.8 0.2 0.041 14.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 ETS83315.1 - 0.019 14.9 0.0 0.13 12.1 0.0 2.1 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 ETS83315.1 - 0.019 14.7 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Oxidored_nitro PF00148.19 ETS83315.1 - 0.023 13.5 0.0 1.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase DUF815 PF05673.13 ETS83315.1 - 0.025 13.8 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Rad17 PF03215.15 ETS83315.1 - 0.029 14.3 0.1 0.083 12.8 0.1 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain NB-ARC PF00931.22 ETS83315.1 - 0.032 13.4 0.1 0.17 11.0 0.0 2.1 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.6 ETS83315.1 - 0.033 13.9 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 ETS83315.1 - 0.042 13.0 0.0 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain Zeta_toxin PF06414.12 ETS83315.1 - 0.049 12.9 0.3 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Sigma54_activ_2 PF14532.6 ETS83315.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 ETS83315.1 - 0.061 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ETS83315.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 ETS83315.1 - 0.07 13.6 0.6 0.33 11.4 0.1 2.3 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ETS83315.1 - 0.078 13.5 0.0 0.21 12.1 0.0 1.8 2 0 0 2 2 1 0 ABC transporter TsaE PF02367.17 ETS83315.1 - 0.096 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 ETS83315.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Parvo_NS1 PF01057.17 ETS83315.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 LysM PF01476.20 ETS83316.1 - 0.097 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 LysM domain Arv1 PF04161.13 ETS83317.1 - 5.1e-79 265.3 0.0 6.1e-79 265.0 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family NAD_binding_2 PF03446.15 ETS83318.1 - 3.7e-15 56.4 0.0 6.5e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ETS83318.1 - 4.9e-07 30.0 0.5 6.9e-07 29.5 0.5 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 ETS83319.1 - 0.00028 21.1 0.1 0.00029 21.0 0.1 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 ETS83319.1 - 0.0014 18.7 0.0 0.0014 18.7 0.0 1.0 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 ETS83319.1 - 0.012 16.2 0.1 0.013 16.0 0.1 1.1 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Radical_SAM PF04055.21 ETS83320.1 - 3.7e-10 40.5 0.0 6.9e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 ETS83320.1 - 4.7e-05 23.7 0.0 7.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 ETS83320.1 - 0.013 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF1681 PF07933.14 ETS83321.1 - 3.8e-56 188.9 0.0 4.8e-56 188.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) CAP_N PF01213.19 ETS83321.1 - 0.75 9.2 4.9 1.5 8.2 4.2 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Lon_C PF05362.13 ETS83322.1 - 2.1e-64 216.8 0.0 4.3e-64 215.8 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 ETS83322.1 - 3e-31 109.0 0.2 9.8e-31 107.2 0.1 2.0 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 ETS83322.1 - 1.6e-21 77.1 0.0 6.2e-21 75.2 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 ETS83322.1 - 1e-07 31.8 0.0 2.9e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 ETS83322.1 - 7.8e-07 29.2 0.0 2.1e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ETS83322.1 - 1.1e-06 28.9 0.0 6e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 ETS83322.1 - 3.6e-05 22.8 0.0 7.5e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 ETS83322.1 - 5.1e-05 23.1 0.1 0.00053 19.8 0.0 2.6 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ETS83322.1 - 6e-05 23.3 0.0 0.00095 19.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS83322.1 - 0.00036 21.0 0.1 0.0029 18.0 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 ETS83322.1 - 0.0092 16.5 0.6 0.048 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 ETS83322.1 - 0.0095 16.0 0.0 0.049 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain ClpB_D2-small PF10431.9 ETS83322.1 - 0.012 15.6 3.9 0.017 15.1 0.1 2.8 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein SKI PF01202.22 ETS83322.1 - 0.016 15.4 0.6 0.3 11.2 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase DNTTIP1_dimer PF18192.1 ETS83322.1 - 0.029 14.7 0.5 1.5 9.2 0.2 3.3 2 1 0 2 2 2 0 DNTTIP1 dimerisation domain RsgA_GTPase PF03193.16 ETS83322.1 - 0.031 14.2 0.4 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase IstB_IS21 PF01695.17 ETS83322.1 - 0.034 13.9 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 ETS83322.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ETS83322.1 - 0.057 13.8 0.0 0.19 12.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 ETS83322.1 - 0.094 12.2 0.7 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 ETS83322.1 - 0.18 11.9 0.6 18 5.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 ETS83322.1 - 0.98 9.9 4.1 1.1 9.7 0.1 2.8 3 0 0 3 3 2 0 ABC transporter Pkinase PF00069.25 ETS83323.1 - 5.9e-10 39.0 0.0 4.3e-09 36.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS83323.1 - 1.4e-08 34.3 0.0 2.3e-07 30.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ETS83323.1 - 0.1 12.5 1.4 13 5.6 0.1 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family FA_desaturase PF00487.24 ETS83324.1 - 3.7e-18 66.3 12.3 3.7e-18 66.3 12.3 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ETS83324.1 - 1e-17 64.1 0.1 3.2e-17 62.4 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain SNF2_N PF00176.23 ETS83325.1 - 7.4e-73 245.3 0.0 1.1e-72 244.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS83325.1 - 1.2e-12 48.2 0.0 3.8e-12 46.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 ETS83325.1 - 0.0023 17.8 5.4 0.0061 16.4 5.4 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ETS83325.1 - 0.012 15.5 2.6 0.025 14.6 2.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 ETS83325.1 - 0.019 15.3 1.7 0.047 14.0 1.7 1.6 1 0 0 1 1 1 0 Ring finger domain DZR PF12773.7 ETS83325.1 - 0.55 10.3 2.9 2.4 8.3 2.9 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 ETS83325.1 - 0.76 9.7 2.4 0.56 10.1 0.6 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ETS83325.1 - 1.2 9.1 3.6 3.1 7.7 3.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HMMR_N PF15905.5 ETS83326.1 - 0.56 9.6 2.2 0.74 9.2 2.2 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal RRM_1 PF00076.22 ETS83327.1 - 2.3e-31 107.4 0.0 4.4e-15 55.3 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ETS83327.1 - 0.00014 21.9 0.0 0.091 12.9 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 ETS83327.1 - 0.00074 19.1 0.0 2.1 7.9 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 ETS83327.1 - 0.014 15.3 0.2 13 5.9 0.0 3.3 3 0 0 3 3 3 0 DbpA RNA binding domain DUF4783 PF16022.5 ETS83327.1 - 0.073 13.2 0.0 0.97 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) ArfGap PF01412.18 ETS83328.1 - 0.056 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf ETF PF01012.21 ETS83329.1 - 3.2e-45 154.3 1.2 3.8e-45 154.0 1.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain GATase PF00117.28 ETS83330.1 - 6e-48 163.1 0.0 8.4e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 ETS83330.1 - 9.7e-47 158.0 0.0 2.1e-46 156.9 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 ETS83330.1 - 7e-06 26.0 0.5 0.0035 17.1 0.3 3.0 1 1 1 2 2 2 2 Peptidase C26 DJ-1_PfpI PF01965.24 ETS83330.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family 2-oxogl_dehyd_N PF16078.5 ETS83330.1 - 0.062 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus adh_short PF00106.25 ETS83331.1 - 4e-84 281.0 12.4 4.5e-44 150.3 2.0 2.5 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS83331.1 - 8.2e-66 221.9 9.0 4.3e-36 124.6 1.7 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 ETS83331.1 - 2.2e-34 117.7 0.0 4.9e-34 116.5 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 ETS83331.1 - 4.4e-29 101.7 3.9 5.2e-14 52.6 0.5 2.3 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 ETS83331.1 - 0.003 16.9 0.3 0.13 11.5 0.3 2.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MaoC_dehydrat_N PF13452.6 ETS83331.1 - 0.0044 17.1 0.0 0.83 9.8 0.0 3.0 3 0 0 3 3 3 1 N-terminal half of MaoC dehydratase Epimerase PF01370.21 ETS83331.1 - 0.59 9.6 2.2 8.7 5.7 0.1 2.6 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family DUF543 PF04418.12 ETS83331.1 - 0.66 10.0 6.7 11 6.1 1.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Glucodextran_B PF09136.10 ETS83331.1 - 1.3 9.5 4.5 0.38 11.2 0.3 2.3 3 0 0 3 3 3 0 Glucodextranase, domain B FAM25 PF15825.5 ETS83331.1 - 1.8 9.0 11.4 1.1 9.7 1.3 3.2 3 0 0 3 3 3 0 FAM25 family 3HCDH_N PF02737.18 ETS83331.1 - 5 7.0 7.9 19 5.1 1.0 2.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SRP54 PF00448.22 ETS83332.1 - 1.3e-06 28.1 0.0 2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MeaB PF03308.16 ETS83332.1 - 0.00036 19.6 0.1 0.00062 18.8 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 ETS83332.1 - 0.0011 19.5 0.0 0.002 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ETS83332.1 - 0.0013 18.7 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain cobW PF02492.19 ETS83332.1 - 0.0054 16.3 0.0 0.0083 15.7 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 ETS83332.1 - 0.0055 16.0 0.0 0.007 15.6 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.6 ETS83332.1 - 0.011 16.2 0.1 0.016 15.6 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_31 PF13614.6 ETS83332.1 - 0.023 14.6 0.1 0.038 13.9 0.1 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ETS83332.1 - 0.027 14.4 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 NTPase ArsA_ATPase PF02374.15 ETS83332.1 - 0.039 13.1 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase CbiA PF01656.23 ETS83332.1 - 0.043 13.9 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 ETS83332.1 - 0.043 13.7 0.1 0.091 12.7 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 ETS83332.1 - 0.046 14.2 0.0 0.098 13.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 ETS83332.1 - 0.054 14.0 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 ETS83332.1 - 0.055 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 ETS83332.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.17 ETS83332.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 ETS83332.1 - 0.078 12.1 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 ETS83332.1 - 0.078 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 ETS83332.1 - 0.084 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 ETS83332.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 ETS83332.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 ETS83332.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ETS83332.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ECM11 PF15463.6 ETS83333.1 - 3.3e-42 144.2 3.8 3.3e-42 144.2 3.8 2.4 2 0 0 2 2 2 1 Extracellular mutant protein 11 DUF4473 PF14747.6 ETS83333.1 - 0.065 13.8 0.1 28 5.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) Mit_KHE1 PF10173.9 ETS83334.1 - 1.1e-62 211.5 0.2 1.7e-62 210.9 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Peptidase_C25 PF01364.18 ETS83334.1 - 0.064 12.4 0.0 0.064 12.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C25 Sulfotransfer_4 PF17784.1 ETS83337.1 - 5.6e-51 173.4 0.0 6.7e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ETS83337.1 - 2.1e-05 25.0 0.0 0.0012 19.3 0.0 2.2 1 1 1 2 2 2 1 Sulfotransferase family DUF5353 PF17304.2 ETS83337.1 - 0.077 12.8 0.3 0.16 11.8 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5353) Methyltransf_23 PF13489.6 ETS83338.1 - 2e-22 79.8 0.0 2.6e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS83338.1 - 2.2e-07 31.5 0.0 6.9e-07 29.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS83338.1 - 4.4e-07 30.6 0.0 5.8e-06 27.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS83338.1 - 1.5e-06 28.1 0.0 1.4e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS83338.1 - 3.3e-05 24.5 0.0 7.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 ETS83338.1 - 0.00054 20.1 0.0 0.0016 18.6 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 ETS83338.1 - 0.018 14.5 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 ETS83338.1 - 0.022 14.1 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain MetW PF07021.12 ETS83338.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 ETS83338.1 - 0.19 11.0 0.0 0.36 10.1 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Tti2 PF10521.9 ETS83339.1 - 2.5e-83 279.9 0.0 4e-83 279.2 0.0 1.3 1 0 0 1 1 1 1 Tti2 family Dopey_N PF04118.14 ETS83339.1 - 0.13 11.3 0.0 0.38 9.8 0.0 1.7 2 0 0 2 2 2 0 Dopey, N-terminal 4HBT PF03061.22 ETS83339.1 - 0.19 12.1 0.0 15 6.0 0.0 2.6 2 0 0 2 2 2 0 Thioesterase superfamily Syja_N PF02383.18 ETS83340.1 - 2.7e-75 253.6 0.0 1.3e-74 251.4 0.0 2.0 2 0 0 2 2 2 1 SacI homology domain DUF1077 PF06417.12 ETS83341.1 - 1.1e-50 170.6 3.9 1.3e-50 170.3 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Adaptin_N PF01602.20 ETS83342.1 - 2.9e-119 399.0 11.8 3.6e-119 398.7 11.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ETS83342.1 - 8.9e-56 188.4 11.7 1.2e-55 188.0 0.6 3.6 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ETS83342.1 - 1.4e-15 57.4 7.5 5.7e-05 23.4 0.0 5.1 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 ETS83342.1 - 9.6e-11 41.0 4.2 0.00081 19.4 0.0 5.6 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 ETS83342.1 - 2.3e-06 28.0 1.5 7.4 7.2 0.0 6.3 6 0 0 6 6 6 1 HEAT-like repeat RTP1_C1 PF10363.9 ETS83342.1 - 0.0018 18.4 1.3 0.4 10.9 0.1 3.4 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 ETS83342.1 - 0.0052 16.4 2.7 0.47 10.0 0.1 3.2 3 1 0 3 3 3 2 CLASP N terminal Arm PF00514.23 ETS83342.1 - 0.013 15.5 0.9 4 7.6 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF4267 PF14087.6 ETS83343.1 - 1.8e-10 40.9 6.4 2e-10 40.7 6.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) ACP_syn_III_C PF08541.10 ETS83343.1 - 0.11 12.7 0.2 0.15 12.3 0.2 1.2 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF2593 PF10767.9 ETS83343.1 - 0.12 12.4 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) BAR_2 PF10455.9 ETS83345.1 - 3.8e-60 203.5 0.6 5.4e-60 203.0 0.6 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 ETS83345.1 - 1.5e-22 80.5 5.9 4.1e-21 75.7 5.9 2.0 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 ETS83345.1 - 0.00017 21.4 1.4 0.00043 20.1 0.4 2.0 2 0 0 2 2 2 1 BAR domain of APPL family CCDC66 PF15236.6 ETS83345.1 - 0.033 14.0 2.3 0.077 12.8 2.3 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 GCP_C_terminal PF04130.13 ETS83345.1 - 0.042 13.3 0.1 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 Gamma tubulin complex component C-terminal YdjC PF04794.12 ETS83345.1 - 0.047 13.7 0.4 0.093 12.7 0.1 1.6 1 1 0 1 1 1 0 YdjC-like protein DUF4360 PF14273.6 ETS83346.1 - 1.4e-31 109.7 0.2 1.6e-31 109.5 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) EIF_2_alpha PF07541.12 ETS83347.1 - 3e-37 127.2 0.0 5.9e-37 126.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 ETS83347.1 - 7.3e-14 51.9 0.7 1.5e-13 50.8 0.7 1.6 1 0 0 1 1 1 1 S1 RNA binding domain cNMP_binding PF00027.29 ETS83348.1 - 3.4e-27 94.4 1.0 1.9e-14 53.5 0.0 5.8 6 0 0 6 6 6 4 Cyclic nucleotide-binding domain Patatin PF01734.22 ETS83348.1 - 3.4e-15 56.8 8.2 5.4e-15 56.1 5.0 2.7 2 1 0 2 2 2 1 Patatin-like phospholipase Cupin_8 PF13621.6 ETS83349.1 - 6e-29 101.5 0.0 1.9e-28 99.9 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 ETS83349.1 - 8.4e-11 41.9 0.0 9.3e-07 28.6 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 ETS83349.1 - 4.5e-05 23.9 0.0 0.0022 18.4 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 ETS83349.1 - 0.014 15.1 0.0 0.082 12.6 0.0 2.1 2 0 0 2 2 2 0 Cupin domain His_Phos_1 PF00300.22 ETS83350.1 - 0.00064 19.5 0.1 0.75 9.4 0.0 2.5 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Z1 PF10593.9 ETS83350.1 - 0.055 13.0 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Z1 domain PolyA_pol PF01743.20 ETS83351.1 - 9.9e-27 93.9 0.2 3.6e-26 92.1 0.1 2.0 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 ETS83351.1 - 7.6e-08 32.0 0.0 2.2e-07 30.6 0.0 1.8 1 1 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Egh16-like PF11327.8 ETS83352.1 - 1.7e-54 185.0 7.9 2.1e-54 184.7 7.9 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor I-set PF07679.16 ETS83352.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain Tannase PF07519.11 ETS83354.1 - 0.041 12.8 0.0 0.041 12.8 0.0 1.1 1 0 0 1 1 1 0 Tannase and feruloyl esterase Suf PF05843.14 ETS83355.1 - 4.7e-12 46.5 10.0 0.05 13.6 0.0 6.7 4 3 2 6 6 6 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 ETS83355.1 - 2e-11 43.7 22.4 1.2 10.1 0.1 11.6 9 4 4 13 13 13 3 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 ETS83355.1 - 8.4e-07 29.0 7.4 1 9.3 0.1 6.4 6 0 0 6 6 6 3 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 ETS83355.1 - 0.00012 22.3 4.5 0.94 9.8 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.9 ETS83355.1 - 0.00051 19.8 0.2 0.022 14.5 0.1 3.6 4 1 0 4 4 4 1 26S proteasome subunit RPN7 TPR_8 PF13181.6 ETS83355.1 - 0.0011 18.9 4.1 0.27 11.6 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.10 ETS83355.1 - 0.021 13.9 0.2 0.021 13.9 0.2 5.5 2 2 4 6 6 6 0 NRDE-2, necessary for RNA interference TPR_4 PF07721.14 ETS83355.1 - 0.13 13.0 0.2 6.3 7.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ETS83355.1 - 1.7 8.9 14.7 14 6.1 0.1 6.9 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_10 PF13374.6 ETS83355.1 - 5.5 7.0 15.3 27 4.8 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat ATP-synt_D PF01813.17 ETS83356.1 - 1.1e-63 214.7 0.7 1.7e-63 214.0 0.7 1.3 1 0 0 1 1 1 1 ATP synthase subunit D HtrL_YibB PF09612.10 ETS83356.1 - 0.066 12.7 0.2 0.1 12.1 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) CobA_CobO_BtuR PF02572.15 ETS83356.1 - 0.098 12.9 2.0 0.59 10.4 0.1 2.3 1 1 1 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP RRM_1 PF00076.22 ETS83358.1 - 4.1e-25 87.4 0.1 9.6e-12 44.6 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ETS83358.1 - 0.005 16.4 0.0 0.97 9.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 ETS83358.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4523) Kei1 PF08552.11 ETS83359.1 - 1.1e-53 182.0 16.7 3.4e-46 157.5 5.4 2.1 1 1 1 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 DUF3149 PF11346.8 ETS83359.1 - 0.64 9.7 5.1 2.1 8.1 1.7 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3149) DUF2975 PF11188.8 ETS83359.1 - 0.79 9.6 6.5 2 8.3 6.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) NIR_SIR PF01077.22 ETS83360.1 - 1.5e-52 177.3 0.2 5.2e-47 159.3 0.1 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 ETS83360.1 - 6.4e-31 106.0 0.0 9.8e-15 54.2 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 ETS83360.1 - 7.2e-29 100.8 0.0 1.8e-28 99.6 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 ETS83360.1 - 2.5e-08 34.0 0.2 9.7e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg SPATA3 PF15662.5 ETS83360.1 - 3.1 8.4 5.6 13 6.3 0.0 2.5 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family VEFS-Box PF09733.9 ETS83361.1 - 0.2 11.5 1.7 0.23 11.2 0.2 1.8 2 0 0 2 2 2 0 VEFS-Box of polycomb protein Chitin_synth_1 PF01644.17 ETS83362.1 - 8.8e-77 256.7 0.1 1.4e-76 256.0 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ETS83362.1 - 8.8e-28 96.1 0.1 1.9e-27 95.0 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ETS83362.1 - 1.2e-20 73.7 6.3 1.1e-18 67.2 0.0 2.5 2 1 1 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ETS83362.1 - 5.5e-06 26.4 0.6 5.5e-06 26.4 0.6 2.1 3 0 0 3 3 3 1 Glycosyl transferase family group 2 ABC_tran PF00005.27 ETS83363.1 - 1.4e-23 83.9 0.0 6.2e-11 43.0 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ETS83363.1 - 2.1e-07 31.1 4.5 0.026 14.4 0.0 3.5 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 ETS83363.1 - 1.1e-05 25.6 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 ETS83363.1 - 9.8e-05 22.9 0.4 0.002 18.6 0.6 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ETS83363.1 - 0.00058 19.6 0.1 0.087 12.6 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ETS83363.1 - 0.011 16.1 0.0 4.8 7.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 ETS83363.1 - 0.017 14.8 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ETS83363.1 - 0.079 13.5 0.0 8.9 6.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ETS83363.1 - 0.091 12.8 0.0 20 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ETS83363.1 - 0.11 12.6 0.0 13 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ETS83363.1 - 0.12 12.8 0.0 7 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 ETS83363.1 - 0.18 12.2 0.1 1.5 9.2 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 ETS83363.1 - 0.2 11.4 0.0 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.6 ETS83363.1 - 0.33 10.6 0.5 3.9 7.1 0.5 2.0 2 0 0 2 2 2 0 AAA ATPase domain UMP1 PF05348.11 ETS83364.1 - 2.9e-42 143.6 0.0 3.3e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.6 ETS83365.1 - 2.1e-13 50.3 0.0 4.6e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ETS83365.1 - 8.3e-05 22.3 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 ETS83365.1 - 0.0019 18.7 0.0 0.0056 17.2 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Herpes_LMP1 PF05297.11 ETS83365.1 - 4.8 6.3 6.5 6.4 5.9 6.5 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) MFS_1 PF07690.16 ETS83366.1 - 3.7e-29 101.8 47.3 1.1e-28 100.2 42.6 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS83366.1 - 1.4e-21 76.6 22.7 2e-21 76.1 22.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ETS83367.1 - 1e-32 113.5 33.2 1e-32 113.5 33.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily NAD_binding_7 PF13241.6 ETS83368.1 - 1.2e-26 93.1 0.0 3.8e-26 91.5 0.0 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 ETS83368.1 - 1.3e-25 88.8 0.0 2.4e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 ETS83368.1 - 9.4e-14 50.6 0.0 1.5e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 ETS83368.1 - 0.036 13.3 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FYVE PF01363.21 ETS83369.1 - 1.1e-23 83.1 19.0 3.6e-17 62.3 5.6 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 ETS83369.1 - 7.4e-17 60.8 1.2 1.8e-16 59.5 1.2 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 ETS83369.1 - 0.00066 19.8 1.7 0.00066 19.8 1.7 3.8 3 1 1 4 4 3 1 AN1-like Zinc finger zf-Di19 PF05605.12 ETS83369.1 - 0.00086 19.6 7.3 0.026 14.8 0.1 2.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding ABC_tran_CTD PF16326.5 ETS83369.1 - 0.0055 16.9 6.2 0.21 11.9 1.5 2.6 2 0 0 2 2 2 2 ABC transporter C-terminal domain DUF1664 PF07889.12 ETS83369.1 - 0.11 12.5 1.0 0.27 11.3 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 ETS83369.1 - 0.11 12.7 3.3 0.15 12.3 1.3 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-C2H2_12 PF18658.1 ETS83369.1 - 0.21 11.2 1.4 0.29 10.7 0.0 2.0 2 0 0 2 2 1 0 Zinc-finger C2H2-type Siva PF05458.12 ETS83369.1 - 0.33 10.6 4.8 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Cnn_1N PF07989.11 ETS83369.1 - 0.38 10.9 4.2 0.41 10.8 1.0 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 T3SSipB PF16535.5 ETS83369.1 - 0.53 10.8 3.0 1.8 9.0 3.0 1.9 1 1 0 1 1 1 0 Type III cell invasion protein SipB zf-C2H2_9 PF16293.5 ETS83369.1 - 0.54 10.1 2.8 9.7 6.1 0.0 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) DUF2225 PF09986.9 ETS83369.1 - 0.93 9.2 4.3 6.2 6.5 3.1 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2HC5 PF06221.13 ETS83369.1 - 1.2 9.1 15.7 8.6 6.4 0.3 4.3 3 1 1 4 4 4 0 Putative zinc finger motif, C2HC5-type zf-ribbon_3 PF13248.6 ETS83369.1 - 1.3 8.5 13.4 4.2 6.9 0.9 4.8 5 0 0 5 5 5 0 zinc-ribbon domain bZIP_1 PF00170.21 ETS83369.1 - 1.4 9.1 0.0 1.4 9.1 0.0 3.4 4 0 0 4 4 3 0 bZIP transcription factor TMF_TATA_bd PF12325.8 ETS83369.1 - 1.7 8.9 11.7 0.19 12.0 3.8 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Rad50_zn_hook PF04423.14 ETS83369.1 - 1.9 8.4 4.3 6.3 6.7 0.1 3.5 3 0 0 3 3 3 0 Rad50 zinc hook motif Val_tRNA-synt_C PF10458.9 ETS83369.1 - 2.5 8.4 5.6 30 5.0 0.1 3.1 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm HypA PF01155.19 ETS83369.1 - 4.9 7.2 12.2 1.6 8.8 0.3 3.8 4 0 0 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CLLAC PF15675.5 ETS83370.1 - 0.025 14.1 0.4 0.043 13.4 0.4 1.4 1 0 0 1 1 1 0 CLLAC-motif containing domain DUF3535 PF12054.8 ETS83372.1 - 9e-124 414.0 0.0 4.2e-122 408.5 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 ETS83372.1 - 8e-65 218.8 0.0 1.9e-64 217.6 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS83372.1 - 5.3e-19 68.6 0.0 3e-18 66.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT PF02985.22 ETS83372.1 - 1.1e-17 62.6 4.7 0.007 16.5 0.0 8.4 8 0 0 8 8 7 4 HEAT repeat HEAT_2 PF13646.6 ETS83372.1 - 3.6e-08 33.7 7.1 0.00024 21.4 0.0 6.2 6 0 0 6 6 5 1 HEAT repeats Vac14_Fab1_bd PF12755.7 ETS83372.1 - 2.3e-06 28.1 0.2 0.52 10.9 0.0 3.9 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region DEAD PF00270.29 ETS83372.1 - 0.00032 20.5 0.0 0.0013 18.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase HEAT_EZ PF13513.6 ETS83372.1 - 0.0013 19.2 8.9 12 6.5 0.0 7.3 8 0 0 8 8 8 1 HEAT-like repeat CLASP_N PF12348.8 ETS83372.1 - 0.0029 17.2 0.2 2.5 7.6 0.0 3.1 3 0 0 3 3 3 2 CLASP N terminal TIP120 PF08623.10 ETS83372.1 - 0.012 15.4 1.0 9.9 5.9 0.1 3.9 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) Cnd1 PF12717.7 ETS83372.1 - 0.015 15.3 0.0 4.4 7.3 0.0 3.8 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 ERCC3_RAD25_C PF16203.5 ETS83372.1 - 0.07 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SMC_N PF02463.19 ETS83373.1 - 3.4e-60 203.2 20.6 7.6e-60 202.1 20.6 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ETS83373.1 - 2.8e-26 92.1 0.0 9.6e-26 90.4 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 ETS83373.1 - 7.5e-17 62.1 10.2 3.7e-09 36.8 0.1 4.5 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ETS83373.1 - 5.7e-13 49.8 25.9 5.7e-13 49.8 25.9 7.9 3 2 3 6 6 6 2 AAA domain AAA_15 PF13175.6 ETS83373.1 - 3.4e-12 46.7 59.4 9.3e-10 38.7 20.8 4.7 2 2 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 ETS83373.1 - 0.00059 20.0 0.0 0.0021 18.3 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 ETS83373.1 - 0.01 15.5 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain BRE1 PF08647.11 ETS83373.1 - 0.011 15.8 5.4 0.011 15.8 5.4 8.5 6 1 2 8 8 8 0 BRE1 E3 ubiquitin ligase PUB PF09409.10 ETS83373.1 - 0.03 14.2 0.1 0.15 12.0 0.0 2.3 2 0 0 2 2 2 0 PUB domain DEAD PF00270.29 ETS83374.1 - 2.2e-40 138.3 0.5 3.8e-40 137.5 0.5 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS83374.1 - 7.9e-29 100.2 0.0 4.2e-28 97.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS83374.1 - 6.7e-08 32.7 0.0 1.7e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_S46 PF10459.9 ETS83374.1 - 0.039 12.6 5.8 0.037 12.7 4.5 1.5 2 0 0 2 2 2 0 Peptidase S46 HAD_SAK_1 PF10307.9 ETS83374.1 - 0.092 12.5 0.6 0.17 11.7 0.6 1.4 1 0 0 1 1 1 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins CMS1 PF14617.6 ETS83374.1 - 0.14 11.5 0.1 0.14 11.5 0.1 2.7 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit E1-E2_ATPase PF00122.20 ETS83375.1 - 2.9e-37 128.0 5.6 3.9e-36 124.3 0.2 3.9 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 ETS83375.1 - 1.5e-18 67.8 0.1 4.1e-18 66.4 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ETS83375.1 - 5.2e-10 38.9 0.0 1.6e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ETS83375.1 - 0.0032 17.2 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1899 PF08953.11 ETS83376.1 - 4.6e-35 119.3 0.3 9e-35 118.4 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 ETS83376.1 - 1.4e-18 66.4 0.1 3.2e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 ETS83376.1 - 9.7e-16 57.9 4.4 0.00027 21.6 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS83376.1 - 2.7e-05 24.4 0.1 0.44 10.9 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ETS83376.1 - 0.00019 20.2 0.1 0.068 11.8 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.11 ETS83376.1 - 0.0022 17.9 0.0 0.027 14.4 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A FAM76 PF16046.5 ETS83376.1 - 0.41 10.0 1.6 0.65 9.3 1.6 1.2 1 0 0 1 1 1 0 FAM76 protein SlyX PF04102.12 ETS83376.1 - 1.4 9.6 7.3 0.28 11.8 2.8 2.1 2 0 0 2 2 2 0 SlyX POB3_N PF17292.2 ETS83377.1 - 4.4e-31 107.1 0.6 2.4e-29 101.6 0.2 2.9 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 ETS83377.1 - 8.8e-31 105.6 0.3 5.9e-30 103.0 0.0 2.4 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 ETS83377.1 - 1.8e-22 79.6 0.0 1.5e-21 76.6 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like RE_Bsp6I PF09504.10 ETS83377.1 - 0.11 12.1 0.2 0.26 10.9 0.2 1.5 1 0 0 1 1 1 0 Bsp6I restriction endonuclease Anillin PF08174.11 ETS83378.1 - 5.8e-12 46.2 0.0 1.5e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 ETS83378.1 - 8.5e-09 35.9 0.0 3.4e-08 34.0 0.0 2.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 ETS83378.1 - 0.022 15.2 0.1 0.081 13.4 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain AhpC-TSA_2 PF13911.6 ETS83379.1 - 1.5e-07 31.6 0.0 3.5e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 ETS83379.1 - 9.1e-06 25.6 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Tubulin_3 PF14881.6 ETS83380.1 - 1.2e-78 263.0 0.0 1.9e-78 262.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 ETS83380.1 - 1.9e-43 147.5 0.0 5.6e-43 146.0 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 ETS83380.1 - 1.4e-05 25.4 0.0 0.14 12.4 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain His_biosynth PF00977.21 ETS83381.1 - 7.2e-34 117.2 0.0 8.7e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein DUF4602 PF15375.6 ETS83382.1 - 5.9e-07 29.9 24.8 7.1e-05 23.1 24.8 2.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) eIF-3c_N PF05470.12 ETS83382.1 - 0.04 12.2 6.2 0.043 12.1 6.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DNA_pol_phi PF04931.13 ETS83382.1 - 0.11 10.6 17.2 0.13 10.4 17.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 ETS83382.1 - 0.55 8.4 18.9 0.74 7.9 18.9 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 ETS83382.1 - 2.5 7.4 28.6 4.7 6.6 28.6 1.5 1 1 0 1 1 1 0 SDA1 STE PF02200.16 ETS83383.1 - 3.5e-56 188.3 0.1 6.2e-56 187.5 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 ETS83383.1 - 0.00096 19.5 4.2 0.0024 18.2 4.2 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS83383.1 - 0.034 15.0 2.4 0.097 13.6 2.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Yippee-Mis18 PF03226.14 ETS83384.1 - 2.1e-10 40.7 0.3 2.1e-10 40.7 0.3 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cytochrom_c3_2 PF14537.6 ETS83384.1 - 0.029 14.8 0.1 0.029 14.8 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c3 HNH_5 PF14279.6 ETS83384.1 - 0.036 13.9 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 HNH endonuclease Ferric_reduct PF01794.19 ETS83385.1 - 3.6e-21 75.6 11.8 1.2e-20 73.9 11.8 2.0 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ETS83385.1 - 2.2e-20 73.4 0.0 1.3e-17 64.3 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ETS83385.1 - 5.9e-14 52.1 0.0 2.6e-12 46.8 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain DUF1206 PF06724.11 ETS83385.1 - 0.0039 17.2 0.5 0.0039 17.2 0.5 4.3 4 0 0 4 4 4 1 Domain of Unknown Function (DUF1206) SPOUT_MTase PF02590.17 ETS83385.1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase SOG2 PF10428.9 ETS83386.1 - 4.2 6.5 8.7 1.3 8.1 5.7 1.6 2 0 0 2 2 2 0 RAM signalling pathway protein CLU PF13236.6 ETS83387.1 - 1.3e-74 250.7 0.0 2.7e-74 249.7 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 ETS83387.1 - 4.7e-50 170.0 0.1 1.8e-49 168.1 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.6 ETS83387.1 - 2.9e-24 85.2 0.0 7.3e-24 83.9 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.6 ETS83387.1 - 5.6e-24 84.2 12.6 2.2e-09 37.5 0.1 3.8 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 ETS83387.1 - 2e-21 75.1 1.7 6.5e-06 25.8 0.5 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat DUF727 PF05303.12 ETS83387.1 - 7.1e-06 26.0 0.1 0.00019 21.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF727) TPR_8 PF13181.6 ETS83387.1 - 0.00011 22.1 2.1 0.024 14.8 0.5 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ETS83387.1 - 0.0023 17.9 4.8 0.073 13.2 0.7 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 ETS83387.1 - 0.11 13.2 2.3 12 6.8 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 ETS83387.1 - 0.14 12.0 2.0 0.22 11.4 0.5 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Adaptin_binding PF10199.9 ETS83387.1 - 0.73 10.5 14.2 0.5 11.0 10.0 2.7 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 RP-C_C PF11800.8 ETS83387.1 - 4.3 7.4 10.7 11 6.1 4.7 2.7 2 0 0 2 2 2 0 Replication protein C C-terminal region Mak16 PF04874.14 ETS83387.1 - 6.4 7.5 14.6 2 9.1 10.6 2.3 2 0 0 2 2 1 0 Mak16 protein C-terminal region SKA1 PF07160.12 ETS83387.1 - 6.9 6.5 9.5 11 5.8 2.9 2.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Forkhead PF00250.18 ETS83388.1 - 3.7e-34 116.8 0.4 6.7e-34 116.0 0.4 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 ETS83388.1 - 7.8e-07 29.4 0.0 1.6e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ETS83388.1 - 0.091 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain zf-C2H2 PF00096.26 ETS83389.1 - 1.8e-06 28.1 14.2 0.0058 17.0 2.0 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ETS83389.1 - 0.0014 19.0 8.6 3.4 8.3 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ETS83389.1 - 0.19 12.6 13.9 0.12 13.2 1.7 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger Sporozoite_P67 PF05642.11 ETS83389.1 - 0.27 9.3 2.7 0.51 8.4 2.7 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-Di19 PF05605.12 ETS83389.1 - 0.48 10.7 6.4 0.36 11.2 1.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding ADH_N PF08240.12 ETS83390.1 - 4.8e-27 94.0 4.9 8e-27 93.3 4.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS83390.1 - 2.4e-17 63.1 0.0 3.8e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS83390.1 - 5.2e-06 26.1 0.0 6.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 ETS83390.1 - 0.0029 16.9 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 ETS83390.1 - 0.022 15.8 0.0 0.037 15.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Metallothi_Euk2 PF12809.7 ETS83390.1 - 0.037 14.3 3.5 0.071 13.4 3.5 1.4 1 0 0 1 1 1 0 Eukaryotic metallothionein Sen15 PF09631.10 ETS83391.1 - 3.4e-23 81.8 0.0 4.2e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein DUF2985 PF11204.8 ETS83392.1 - 9.1e-36 121.9 1.1 2e-35 120.8 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Nuc_sug_transp PF04142.15 ETS83393.1 - 1.3e-10 40.9 0.5 2.2e-10 40.2 0.5 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 ETS83393.1 - 2.7e-06 27.6 29.2 0.0064 16.7 13.6 2.8 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 ETS83393.1 - 0.00056 19.4 2.7 0.00056 19.4 2.7 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family DUF423 PF04241.15 ETS83393.1 - 0.069 13.4 2.0 1.7 8.9 0.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF423) TrbC PF04956.13 ETS83393.1 - 1.1 9.5 12.2 3.9 7.8 4.0 3.4 3 0 0 3 3 3 0 TrbC/VIRB2 family PDR_assoc PF08370.11 ETS83393.1 - 2.1 8.2 11.3 9.8 6.0 0.5 4.0 4 0 0 4 4 4 0 Plant PDR ABC transporter associated DUF2530 PF10745.9 ETS83393.1 - 2.8 8.3 15.3 0.76 10.1 4.5 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) Peptidase_C2 PF00648.21 ETS83394.1 - 3.2e-27 95.3 0.0 5.6e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 ETS83394.1 - 7.4e-10 39.2 0.0 0.0033 17.7 0.0 3.6 3 0 0 3 3 3 3 Calpain large subunit, domain III MFS_1 PF07690.16 ETS83395.1 - 6.2e-39 133.9 33.5 6.2e-39 133.9 33.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS83395.1 - 8.1e-09 34.8 6.6 8.1e-09 34.8 6.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 ETS83395.1 - 0.00016 20.1 5.1 0.00053 18.4 0.2 2.5 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Mito_carr PF00153.27 ETS83396.1 - 1.9e-55 184.8 0.6 9.7e-20 70.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L29e PF01779.17 ETS83397.1 - 3e-22 78.6 9.7 4.7e-22 78.0 9.7 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family SAM_2 PF07647.17 ETS83398.1 - 6.6e-09 35.8 0.1 1.2e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ETS83398.1 - 0.00011 22.6 0.2 0.00022 21.6 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 ETS83398.1 - 0.067 13.3 0.2 0.18 11.9 0.1 1.7 2 0 0 2 2 2 0 IGR protein motif DUF4508 PF14969.6 ETS83398.1 - 0.076 13.3 0.3 0.27 11.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) TPR_2 PF07719.17 ETS83399.1 - 1.7e-09 37.1 33.1 0.024 14.7 0.1 10.6 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 ETS83399.1 - 1.1e-07 31.5 14.3 0.13 12.5 0.0 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 ETS83399.1 - 1.9e-07 30.6 6.8 0.2 11.4 0.0 7.1 8 0 0 8 8 8 2 TPR repeat TPR_1 PF00515.28 ETS83399.1 - 4.4e-06 26.3 28.5 0.024 14.4 0.1 9.3 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_20 PF14561.6 ETS83399.1 - 6.7e-06 26.4 5.7 0.23 11.8 0.1 5.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 ETS83399.1 - 5.3e-05 23.3 8.8 4.3 7.9 0.0 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 ETS83399.1 - 0.00012 21.9 22.4 0.011 15.7 0.1 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 ETS83399.1 - 0.00018 22.1 37.6 9.6 7.3 0.1 11.3 7 3 4 11 11 11 1 Tetratricopeptide repeat TPR_12 PF13424.6 ETS83399.1 - 0.00082 19.6 14.6 0.0054 17.0 6.9 8.6 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.6 ETS83399.1 - 0.0023 18.5 16.3 2.2 9.1 0.2 6.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ETS83399.1 - 0.042 14.5 0.2 0.042 14.5 0.2 9.0 7 2 2 9 9 9 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 ETS83399.1 - 0.18 12.3 2.7 6.3 7.3 0.0 3.7 4 0 0 4 4 3 0 Alkyl sulfatase dimerisation ANAPC3 PF12895.7 ETS83399.1 - 0.26 11.5 19.5 1.9 8.8 3.1 6.8 7 1 1 8 8 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 ETS83399.1 - 1.1 9.8 31.2 4 8.0 0.4 8.6 6 2 3 9 9 9 0 Tetratricopeptide repeat TPR_3 PF07720.12 ETS83399.1 - 5.2 7.2 5.5 36 4.5 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Cupin_2 PF07883.11 ETS83400.1 - 3.1e-05 23.6 0.0 6.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 ETS83400.1 - 0.026 14.3 0.1 0.032 14.0 0.1 1.2 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 ETS83400.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Rota_NS6 PF04866.12 ETS83401.1 - 0.044 14.0 0.1 0.094 12.9 0.1 1.4 1 0 0 1 1 1 0 Rotavirus non-structural protein 6 Transp_cyt_pur PF02133.15 ETS83402.1 - 1.3e-86 291.2 36.8 1.6e-86 290.9 36.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 ETS83403.1 - 1.6e-39 135.8 48.5 3.2e-35 121.7 49.7 3.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Sec61_beta PF03911.16 ETS83403.1 - 0.12 12.5 0.3 0.12 12.5 0.3 3.2 4 0 0 4 4 4 0 Sec61beta family OATP PF03137.20 ETS83403.1 - 2.1 6.6 17.0 0.65 8.2 4.0 2.9 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Polysacc_deac_1 PF01522.21 ETS83404.1 - 2.1e-09 37.4 0.0 3.7e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF3146 PF11344.8 ETS83404.1 - 0.0026 17.4 0.1 0.029 14.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3146) Fungal_trans PF04082.18 ETS83405.1 - 1.7e-30 106.0 0.3 2.6e-30 105.3 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SMN PF06003.12 ETS83405.1 - 0.14 11.4 0.2 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) MFS_1 PF07690.16 ETS83406.1 - 1.4e-41 142.7 95.1 2.8e-34 118.6 65.2 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS83406.1 - 0.029 13.2 36.3 0.0081 15.1 12.2 2.9 2 1 1 3 3 3 0 Sugar (and other) transporter LapA_dom PF06305.11 ETS83407.1 - 0.051 13.4 0.5 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Tubulin PF00091.25 ETS83408.1 - 2e-63 214.2 0.0 3.1e-63 213.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ETS83408.1 - 8.4e-28 97.1 0.0 1.4e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ETS83408.1 - 6.9e-06 26.4 0.1 1.2e-05 25.6 0.1 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 ETS83408.1 - 2.2e-05 24.2 0.3 5.9e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Tubulin domain HP1451_C PF18472.1 ETS83408.1 - 0.12 12.3 0.0 0.51 10.4 0.0 2.0 2 0 0 2 2 2 0 HP1451 C-terminal domain His_Phos_2 PF00328.22 ETS83409.1 - 3.8e-28 98.9 0.0 4.8e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AAA PF00004.29 ETS83410.1 - 4.5e-06 27.1 0.2 5.3e-05 23.7 0.2 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ETS83410.1 - 0.0011 18.9 0.0 0.13 12.1 0.0 3.0 3 0 0 3 3 3 1 Rad17 P-loop domain APC_u9 PF16633.5 ETS83410.1 - 0.0036 18.4 0.8 1.4 10.0 0.2 3.7 3 0 0 3 3 3 1 Unstructured region on APC between 1st two creatine-rich regions AAA_16 PF13191.6 ETS83410.1 - 0.0049 17.3 0.0 0.016 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ETS83410.1 - 0.0054 17.3 0.0 0.015 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 ETS83410.1 - 0.034 13.2 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 ETS83410.1 - 0.079 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TIP49 PF06068.13 ETS83410.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 ETS83410.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 ETS83410.1 - 0.13 12.5 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF1556 PF07590.11 ETS83410.1 - 10 6.5 8.1 1.8 8.9 1.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1556) Utp8 PF10395.9 ETS83411.1 - 2.5e-11 42.9 0.2 5.2e-09 35.2 0.0 2.7 3 0 0 3 3 3 2 Utp8 family SesA PF17107.5 ETS83412.1 - 0.057 13.6 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF883 PF05957.13 ETS83412.1 - 0.066 13.8 1.5 0.35 11.5 0.1 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PTCB-BRCT PF12738.7 ETS83413.1 - 1.2e-41 140.4 0.9 4.9e-24 84.1 0.1 3.6 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 ETS83413.1 - 2.4e-36 124.0 1.4 5.7e-16 58.7 0.1 4.9 6 0 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ETS83413.1 - 1.2e-15 57.7 0.3 5.7e-06 26.6 0.1 4.3 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 ETS83413.1 - 2e-10 40.8 0.4 0.00034 20.8 0.0 4.6 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 ETS83413.1 - 0.0024 17.9 0.1 0.09 12.9 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 ETS83413.1 - 0.044 13.7 0.0 1 9.2 0.0 2.9 3 0 0 3 3 3 0 Regulator of Ty1 transposition protein 107 BRCT domain 2-oxoacid_dh PF00198.23 ETS83416.1 - 4.6e-77 258.6 0.1 6.2e-77 258.2 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ETS83416.1 - 4.7e-19 68.0 0.9 1.3e-18 66.6 0.9 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 ETS83416.1 - 5.6e-12 45.8 0.9 1.8e-11 44.2 0.9 1.9 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.8 ETS83416.1 - 0.015 15.8 0.1 0.041 14.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) Biotin_lipoyl_2 PF13533.6 ETS83416.1 - 0.094 12.6 0.0 0.46 10.4 0.0 2.2 1 0 0 1 1 1 0 Biotin-lipoyl like TFIIF_alpha PF05793.12 ETS83416.1 - 0.17 10.4 4.1 0.24 9.9 4.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribosomal_60s PF00428.19 ETS83416.1 - 5.4 7.7 17.5 10 6.8 8.0 3.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Sec7 PF01369.20 ETS83417.1 - 5.2e-73 244.6 1.0 5.2e-73 244.6 1.0 2.1 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 ETS83417.1 - 7.8e-40 136.4 1.7 7.8e-40 136.4 1.7 3.3 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 ETS83417.1 - 2.2e-32 110.8 10.5 6e-32 109.4 0.1 5.8 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 ETS83417.1 - 1.4e-20 73.7 2.9 4.9e-18 65.4 0.2 3.5 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 BTV_NS2 PF04514.12 ETS83417.1 - 0.2 10.5 1.5 0.41 9.4 1.5 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 p450 PF00067.22 ETS83419.1 - 4.1e-44 151.1 0.0 5.4e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS83421.1 - 6.1e-60 203.3 0.0 7.6e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ldh_1_C PF02866.18 ETS83422.1 - 6e-47 159.7 0.0 1.2e-46 158.8 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 ETS83422.1 - 4.1e-43 146.8 0.1 2.3e-42 144.4 0.0 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 ETS83422.1 - 0.00022 20.3 0.0 0.00033 19.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 ETS83422.1 - 0.074 12.4 0.0 0.6 9.4 0.0 2.3 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 ETS83422.1 - 0.074 13.5 0.2 0.36 11.3 0.0 2.2 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain APH PF01636.23 ETS83423.1 - 1.5e-10 41.4 5.9 2.1e-06 27.9 0.2 3.1 3 0 0 3 3 3 2 Phosphotransferase enzyme family Snf7 PF03357.21 ETS83423.1 - 0.058 13.0 3.5 0.13 11.9 3.5 1.5 1 0 0 1 1 1 0 Snf7 FliJ PF02050.16 ETS83423.1 - 0.61 10.3 16.3 3.7 7.8 7.6 3.2 1 1 1 2 2 2 0 Flagellar FliJ protein DUF4407 PF14362.6 ETS83423.1 - 3 7.1 10.0 6.2 6.1 10.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Aldedh PF00171.22 ETS83425.1 - 1.7e-182 607.1 1.6 1.9e-182 606.9 1.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ETS83425.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1487) Acetyltransf_10 PF13673.7 ETS83426.1 - 1.8e-18 66.7 0.0 2.1e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS83426.1 - 3.4e-14 53.1 0.0 4e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS83426.1 - 4.8e-09 36.5 0.0 6.7e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETS83426.1 - 1.9e-05 24.7 0.0 0.0013 18.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 ETS83426.1 - 7.4e-05 22.9 0.0 0.00011 22.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ETS83426.1 - 0.00018 21.6 0.0 0.00026 21.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 ETS83426.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ zf-C2HC5 PF06221.13 ETS83427.1 - 3e-21 75.2 6.9 4.7e-21 74.5 6.9 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type FYVE PF01363.21 ETS83427.1 - 0.08 13.1 1.4 0.14 12.3 1.4 1.4 1 0 0 1 1 1 0 FYVE zinc finger Aldedh PF00171.22 ETS83428.1 - 2.7e-146 487.7 0.1 3.4e-146 487.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ETS83428.1 - 0.005 16.3 0.0 0.1 12.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) LuxC PF05893.14 ETS83428.1 - 0.048 12.7 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Methyltransf_11 PF08241.12 ETS83429.1 - 0.00075 20.1 0.0 0.0018 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS83429.1 - 0.0014 19.3 0.0 0.0027 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF2917 PF11142.8 ETS83429.1 - 0.04 13.3 0.0 0.4 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2917) Aminotran_5 PF00266.19 ETS83430.1 - 3.3e-17 62.5 0.0 5.5e-17 61.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V SUI1 PF01253.22 ETS83431.1 - 9.8e-19 67.7 0.0 3.7e-18 65.8 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 ETS83431.1 - 2.1e-09 37.9 0.2 8.1e-08 32.9 0.2 3.1 2 1 0 2 2 2 1 Pre-PUA-like domain Kin17_mid PF10357.9 ETS83431.1 - 0.0082 16.1 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein Blt1 PF12754.7 ETS83431.1 - 3 8.2 7.2 18 5.7 0.8 2.9 2 1 0 3 3 3 0 Blt1 N-terminal domain Glyco_hydro_3_C PF01915.22 ETS83432.1 - 4.4e-51 173.7 0.3 1.5e-50 172.0 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS83432.1 - 1.8e-46 159.0 0.0 3.1e-46 158.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS83432.1 - 1.5e-24 85.9 0.0 2.9e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Ser_hydrolase PF06821.13 ETS83432.1 - 0.088 12.7 0.1 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase AA_permease PF00324.21 ETS83433.1 - 1.9e-128 429.1 45.0 2.3e-128 428.8 45.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS83433.1 - 1.5e-25 90.0 49.4 1.9e-25 89.6 49.4 1.0 1 0 0 1 1 1 1 Amino acid permease NCE101 PF11654.8 ETS83433.1 - 0.002 17.8 1.0 0.0067 16.1 1.0 1.9 1 0 0 1 1 1 1 Non-classical export protein 1 DUF3290 PF11694.8 ETS83433.1 - 9.7 6.2 6.6 4.9 7.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) Glyco_tranf_2_3 PF13641.6 ETS83434.1 - 2.2e-17 63.7 0.0 3.1e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Bac_luciferase PF00296.20 ETS83435.1 - 4.3e-65 220.2 0.2 5.9e-65 219.8 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase AMP-binding PF00501.28 ETS83436.1 - 3.9e-30 104.8 0.0 5.9e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ETS83436.1 - 6e-27 94.4 0.0 9.2e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 ETS83436.1 - 1.8e-11 43.9 0.0 3.5e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 ETS83436.1 - 5e-06 26.8 0.0 1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 ETS83436.1 - 0.00081 18.6 0.0 0.034 13.2 0.0 2.6 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 ETS83436.1 - 0.035 14.0 0.2 0.33 10.8 0.0 2.5 3 0 0 3 3 3 0 KR domain LIN52 PF10044.9 ETS83436.1 - 0.086 13.6 0.0 0.29 11.9 0.0 1.9 1 0 0 1 1 1 0 Retinal tissue protein Semialdhyde_dh PF01118.24 ETS83436.1 - 0.1 13.0 0.0 0.39 11.2 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain GYF PF02213.16 ETS83437.1 - 2.1e-17 62.5 0.2 4.2e-17 61.5 0.2 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 ETS83437.1 - 0.012 15.5 0.0 0.03 14.1 0.0 1.8 1 0 0 1 1 1 0 GYF domain 2 TPR_2 PF07719.17 ETS83438.1 - 8.9e-12 44.2 2.7 0.0079 16.2 0.0 4.3 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 ETS83438.1 - 4e-11 42.2 2.0 0.0017 18.1 0.3 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ETS83438.1 - 1.1e-08 35.6 2.8 4e-08 33.8 1.1 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 ETS83438.1 - 2.8e-07 30.2 0.5 0.062 13.6 0.3 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS83438.1 - 7.2e-06 26.4 0.3 0.052 14.1 0.1 4.0 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ETS83438.1 - 0.00014 22.1 6.4 0.099 12.9 0.0 3.5 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 ETS83438.1 - 0.00038 20.6 0.4 0.0014 18.7 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 ETS83438.1 - 0.0024 17.8 0.1 1.1 9.5 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 ETS83438.1 - 0.0048 16.6 0.6 2.2 7.9 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 ETS83438.1 - 0.0048 16.5 0.2 0.57 9.9 0.2 2.9 1 1 1 2 2 2 2 TPR repeat TPR_14 PF13428.6 ETS83438.1 - 0.019 15.7 0.6 0.019 15.7 0.6 5.1 5 1 1 6 6 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ETS83438.1 - 0.021 15.4 1.6 6.2 7.7 0.3 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2877 PF11392.8 ETS83438.1 - 0.076 13.7 0.0 0.32 11.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2877) FOXP-CC PF16159.5 ETS83439.1 - 1.2 9.8 3.7 0.44 11.2 0.6 2.0 2 1 0 2 2 2 0 FOXP coiled-coil domain AAR2 PF05282.11 ETS83440.1 - 3.5e-60 204.3 0.0 4.7e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S9 PF00380.19 ETS83442.1 - 9.7e-34 116.5 0.1 1.1e-33 116.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EAP30 PF04157.16 ETS83443.1 - 3.4e-72 242.5 0.1 3.9e-72 242.4 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family P_C PF06640.11 ETS83443.1 - 0.0074 16.5 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 P protein C-terminus DEAD PF00270.29 ETS83444.1 - 2.4e-50 170.7 0.0 9.4e-49 165.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS83444.1 - 2.5e-31 108.3 0.1 7.1e-31 106.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS83444.1 - 3.1e-05 24.1 0.0 8.3e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 ETS83444.1 - 0.0029 16.4 0.0 0.36 9.5 0.0 2.2 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 ETS83444.1 - 0.015 15.6 0.0 6 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF445 PF04286.12 ETS83444.1 - 0.062 13.1 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF5335 PF17269.2 ETS83444.1 - 0.087 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) DUF2443 PF10398.9 ETS83444.1 - 0.14 12.2 0.2 0.36 10.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) AAA_22 PF13401.6 ETS83444.1 - 0.31 11.3 0.8 33 4.7 0.0 3.3 4 0 0 4 4 4 0 AAA domain Phos_pyr_kin PF08543.12 ETS83445.1 - 5e-86 288.1 0.4 7.1e-86 287.6 0.4 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 ETS83445.1 - 1.2e-48 165.7 0.0 1.9e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 ETS83445.1 - 1.5e-08 34.4 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 ETS83445.1 - 0.01 15.2 1.1 1.4 8.3 0.0 2.7 2 1 0 2 2 2 0 Hydroxyethylthiazole kinase family TPR_1 PF00515.28 ETS83446.1 - 1.2e-17 62.9 8.4 3.7e-08 32.9 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 ETS83446.1 - 9.6e-17 59.7 7.0 3.1e-06 26.9 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 ETS83446.1 - 7.4e-11 42.2 1.1 7.5e-07 29.4 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 ETS83446.1 - 2.7e-09 36.5 4.9 6.5e-06 26.0 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 ETS83446.1 - 1.8e-08 34.5 1.1 0.019 15.5 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 ETS83446.1 - 3.8e-07 29.7 2.5 2.3e-05 24.0 0.5 3.6 2 1 1 3 3 3 1 TPR repeat PB1 PF00564.24 ETS83446.1 - 9.7e-07 28.6 0.4 1.8e-06 27.8 0.4 1.4 1 0 0 1 1 1 1 PB1 domain TPR_7 PF13176.6 ETS83446.1 - 1e-06 28.3 0.2 9.8e-05 22.1 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 ETS83446.1 - 4.2e-06 27.3 2.9 0.0032 18.1 0.2 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 ETS83446.1 - 1.9e-05 24.7 0.3 0.17 12.1 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 ETS83446.1 - 0.0004 20.2 0.1 0.26 11.2 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 ETS83446.1 - 0.0011 19.2 0.3 2.4 8.7 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 ETS83446.1 - 0.0077 17.0 0.6 0.12 13.2 0.1 3.0 1 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC5 PF12862.7 ETS83446.1 - 0.052 13.6 0.2 0.17 12.0 0.1 1.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 ETS83446.1 - 0.11 13.2 0.0 36 5.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3808 PF10300.9 ETS83446.1 - 0.13 11.0 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) HMA PF00403.26 ETS83447.1 - 3.1e-12 46.7 0.2 5.4e-12 46.0 0.2 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 ETS83447.1 - 4.2e-10 39.9 0.0 6.8e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Ribosomal_L13 PF00572.18 ETS83448.1 - 4e-41 140.2 0.0 5.2e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Helo_like_N PF17111.5 ETS83449.1 - 7.5e-06 25.5 0.0 1.2e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank_2 PF12796.7 ETS83450.1 - 1.3e-35 121.8 1.4 2.9e-13 50.2 0.1 4.8 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS83450.1 - 3.7e-30 103.6 6.1 6.5e-07 29.5 0.0 5.7 3 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 ETS83450.1 - 7.3e-24 83.1 7.7 1.9e-05 24.9 0.7 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 ETS83450.1 - 1.6e-21 76.4 7.2 4.8e-05 23.8 0.0 6.4 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS83450.1 - 5.9e-21 72.3 3.8 0.0017 18.7 0.0 7.8 8 0 0 8 8 8 5 Ankyrin repeat Uricase PF01014.18 ETS83451.1 - 2.4e-72 241.4 0.6 1.4e-36 125.6 0.0 2.0 2 0 0 2 2 2 2 Uricase RICTOR_N PF14664.6 ETS83452.1 - 1.2e-134 449.1 0.5 5.1e-134 447.0 0.1 2.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 ETS83452.1 - 1.5e-37 128.3 0.1 1.3e-35 122.0 0.0 3.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 ETS83452.1 - 1.4e-36 124.4 0.0 6.4e-34 115.8 0.0 3.9 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 ETS83452.1 - 9.2e-29 99.5 0.3 1.1e-27 96.1 0.1 3.0 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 ETS83452.1 - 4.5e-13 49.1 8.5 1.3e-12 47.6 8.5 1.8 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.6 ETS83452.1 - 0.0031 17.7 6.1 0.0068 16.6 6.1 1.5 1 0 0 1 1 1 1 Up-regulated During Septation DUF1635 PF07795.11 ETS83452.1 - 0.027 14.3 1.4 0.054 13.3 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) CREPT PF16566.5 ETS83452.1 - 0.2 11.8 3.2 0.44 10.7 3.2 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour RE_HpaII PF09561.10 ETS83452.1 - 0.24 10.8 1.7 0.4 10.0 1.7 1.2 1 0 0 1 1 1 0 HpaII restriction endonuclease HEAT_2 PF13646.6 ETS83452.1 - 0.3 11.5 5.6 33 4.9 0.0 4.5 5 0 0 5 5 3 0 HEAT repeats Seryl_tRNA_N PF02403.22 ETS83452.1 - 2 8.7 11.5 5.3 7.3 11.5 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 ETS83452.1 - 4.1 6.7 6.3 7.9 5.7 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 ETS83452.1 - 4.9 7.2 7.6 12 6.0 7.6 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus RIX1 PF08167.12 ETS83453.1 - 4.6e-54 183.0 4.4 6.1e-54 182.6 3.5 1.7 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis RICTOR_N PF14664.6 ETS83453.1 - 0.0097 14.9 0.2 16 4.4 0.0 3.1 3 0 0 3 3 3 3 Rapamycin-insensitive companion of mTOR, N-term DMRT-like PF15791.5 ETS83453.1 - 0.02 15.3 1.1 0.02 15.3 1.1 2.1 2 0 0 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 TPR_14 PF13428.6 ETS83454.1 - 1.2e-08 35.0 8.6 0.18 12.7 0.2 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 ETS83454.1 - 1.2e-06 28.9 3.8 0.05 14.1 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 ETS83454.1 - 4.6e-05 23.5 3.6 0.16 12.5 0.1 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 ETS83454.1 - 7.8e-05 22.4 1.8 2.3 8.4 0.1 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 ETS83454.1 - 0.00046 20.8 3.4 10 6.8 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 ETS83454.1 - 0.00079 19.2 6.8 0.62 10.0 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 ETS83454.1 - 0.0017 18.3 19.3 0.23 11.7 0.1 7.3 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_20 PF14561.6 ETS83454.1 - 0.0069 16.7 0.0 16 5.9 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ETS83454.1 - 0.0081 16.4 5.1 6.5 7.1 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 ETS83454.1 - 0.021 15.0 0.1 17 5.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 ETS83454.1 - 0.027 14.6 9.1 0.053 13.8 0.0 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat PUL PF08324.11 ETS83454.1 - 0.18 11.0 4.0 2.1 7.5 0.1 3.8 3 2 2 5 5 5 0 PUL domain TPR_6 PF13174.6 ETS83454.1 - 8.5 7.2 8.2 1.8 9.4 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 ETS83455.1 - 2.4e-37 128.7 23.4 8.2e-37 126.9 24.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS83455.1 - 0.00059 18.8 18.9 0.0024 16.8 18.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter SGL PF08450.12 ETS83456.1 - 6.8e-60 202.7 0.0 8.7e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Sin_N PF04801.13 ETS83456.1 - 0.013 14.8 0.2 0.015 14.6 0.2 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region HTH_33 PF13592.6 ETS83456.1 - 0.017 14.7 0.6 0.031 13.9 0.6 1.4 1 0 0 1 1 1 0 Winged helix-turn helix TAF4 PF05236.14 ETS83456.1 - 0.028 14.2 2.9 0.035 13.8 2.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family PIEZO PF15917.5 ETS83456.1 - 0.13 11.8 1.4 0.19 11.2 1.4 1.1 1 0 0 1 1 1 0 Piezo YMF19 PF02326.15 ETS83456.1 - 0.19 12.5 0.3 0.33 11.8 0.3 1.3 1 0 0 1 1 1 0 Plant ATP synthase F0 bZIP_2 PF07716.15 ETS83457.1 - 0.00026 21.0 12.9 0.00048 20.2 12.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper TMF_DNA_bd PF12329.8 ETS83457.1 - 0.034 14.2 3.2 0.051 13.6 3.2 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.21 ETS83457.1 - 0.072 13.2 11.8 0.12 12.4 11.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor EMP24_GP25L PF01105.24 ETS83457.1 - 0.12 12.4 0.5 0.17 11.8 0.5 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DivIC PF04977.15 ETS83457.1 - 2.2 8.1 10.6 2.2 8.1 8.4 1.9 1 1 1 2 2 2 0 Septum formation initiator bZIP_Maf PF03131.17 ETS83457.1 - 6.9 7.3 13.8 14 6.3 13.8 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor adh_short PF00106.25 ETS83459.1 - 7.3e-13 48.4 0.3 1.1e-12 47.8 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS83459.1 - 6.9e-09 35.6 1.5 8.4e-09 35.3 1.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS83459.1 - 6e-07 29.6 1.5 4.9e-05 23.3 0.3 2.2 2 0 0 2 2 2 2 KR domain NmrA PF05368.13 ETS83459.1 - 2.4e-06 27.3 0.6 4.1e-06 26.5 0.6 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS83459.1 - 3.6e-05 23.8 0.5 3.6e-05 23.8 0.5 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 ETS83459.1 - 0.019 14.4 0.7 0.027 13.9 0.2 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF4167 PF13763.6 ETS83459.1 - 0.027 14.6 0.8 0.048 13.8 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) PALP PF00291.25 ETS83459.1 - 0.093 12.1 2.4 0.23 10.8 1.8 1.9 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme CorA PF01544.18 ETS83462.1 - 3e-09 36.6 0.0 5.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein HET PF06985.11 ETS83463.1 - 5.1e-11 43.1 0.0 1.9e-10 41.3 0.0 2.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.22 ETS83463.1 - 2.1e-06 27.1 0.0 3.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.6 ETS83463.1 - 2.4e-05 24.5 1.2 2.4e-05 24.5 1.2 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_16 PF13191.6 ETS83463.1 - 0.0033 17.8 0.2 0.027 14.9 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain TPR_19 PF14559.6 ETS83463.1 - 0.0082 16.6 0.3 1.6 9.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_22 PF13401.6 ETS83463.1 - 0.051 13.8 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain PTB PF08416.13 ETS83463.1 - 0.08 13.1 0.1 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 Phosphotyrosine-binding domain TPR_5 PF12688.7 ETS83463.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Tetratrico peptide repeat AAA_14 PF13173.6 ETS83463.1 - 0.15 12.1 0.0 0.47 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_MalT PF17874.1 ETS83463.1 - 0.55 9.6 5.5 0.052 12.9 0.4 1.7 2 0 0 2 2 2 0 MalT-like TPR region Polysacc_deac_1 PF01522.21 ETS83464.1 - 2e-28 98.7 0.0 3.2e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ETS83464.1 - 2.4e-11 43.9 37.2 1.2e-07 32.0 16.9 3.8 3 0 0 3 3 3 2 Chitin recognition protein SOG2 PF10428.9 ETS83464.1 - 2.7 7.1 9.2 3.7 6.6 9.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein ApbA PF02558.16 ETS83465.1 - 4.3e-29 101.1 0.0 5.8e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 ETS83465.1 - 4.1e-27 94.9 0.0 8e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Sacchrp_dh_NADP PF03435.18 ETS83465.1 - 0.012 15.8 0.1 0.043 14.1 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF4112 PF13430.6 ETS83466.1 - 3.7e-31 107.5 0.6 4.9e-31 107.1 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Ribonuc_red_sm PF00268.21 ETS83467.1 - 8.4e-122 406.0 2.5 1e-121 405.7 2.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.12 ETS83468.1 - 2.2e-33 114.5 0.2 2.8e-33 114.2 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) WD40 PF00400.32 ETS83469.1 - 1e-14 54.6 0.1 9e-06 26.3 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS83469.1 - 4.3e-06 26.9 0.0 0.28 11.5 0.0 4.4 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L19 PF01245.20 ETS83470.1 - 4.5e-13 49.1 0.0 7.7e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 PALP PF00291.25 ETS83472.1 - 7e-63 212.8 0.2 8.4e-63 212.5 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-C3HC4 PF00097.25 ETS83473.1 - 2.1e-07 30.7 4.0 2.1e-07 30.7 4.0 5.2 5 2 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ETS83473.1 - 6.3e-07 29.1 3.3 6.3e-07 29.1 3.3 5.2 6 1 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS83473.1 - 7.1e-07 29.1 3.6 7.1e-07 29.1 3.6 4.6 5 0 0 5 5 5 1 RING-type zinc-finger zf-RING_6 PF14835.6 ETS83473.1 - 7.9e-07 28.9 0.5 7.9e-07 28.9 0.5 3.0 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 ETS83473.1 - 7.3e-06 26.2 5.0 7.3e-06 26.2 5.0 4.9 4 2 0 4 4 4 1 Ring finger domain SH3_1 PF00018.28 ETS83473.1 - 1.4e-05 24.6 0.0 3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain zf-RING_5 PF14634.6 ETS83473.1 - 8.5e-05 22.4 2.6 8.5e-05 22.4 2.6 5.5 5 2 0 5 5 5 1 zinc-RING finger domain SH3_9 PF14604.6 ETS83473.1 - 0.00018 21.3 1.1 0.00054 19.8 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain zf-C3HC4_4 PF15227.6 ETS83473.1 - 0.003 17.7 4.4 0.003 17.7 4.4 4.9 4 3 1 5 5 5 1 zinc finger of C3HC4-type, RING SH3_2 PF07653.17 ETS83473.1 - 0.13 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain ECH_1 PF00378.20 ETS83474.1 - 1e-76 257.6 0.1 1.2e-76 257.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ETS83474.1 - 4.2e-36 125.1 0.3 2.4e-35 122.6 0.3 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 ETS83474.1 - 0.04 13.9 0.0 0.88 9.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 HA70_C PF17993.1 ETS83474.1 - 0.062 13.4 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 Haemagglutinin 70 C-terminal domain Thg1 PF04446.12 ETS83474.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 tRNAHis guanylyltransferase Rer1 PF03248.13 ETS83475.1 - 3.9e-80 267.6 5.4 4.6e-80 267.3 5.4 1.0 1 0 0 1 1 1 1 Rer1 family Paf1 PF03985.13 ETS83476.1 - 6.4e-93 312.0 7.1 7.2e-93 311.9 7.1 1.0 1 0 0 1 1 1 1 Paf1 TrkH PF02386.16 ETS83477.1 - 1.8e-144 481.9 5.4 1.8e-144 481.9 5.4 2.1 2 0 0 2 2 2 2 Cation transport protein ERCC3_RAD25_C PF16203.5 ETS83478.1 - 6.2e-118 392.4 0.3 1.1e-117 391.6 0.3 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 ETS83478.1 - 1.2e-32 112.7 0.0 3.7e-32 111.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS83478.1 - 8.1e-16 58.5 0.0 1.6e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ETS83478.1 - 3.5e-10 40.2 0.1 9e-10 38.9 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 ETS83478.1 - 8e-08 31.4 0.0 1.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain TruD PF01142.18 ETS83479.1 - 1e-60 205.8 0.4 3.2e-53 181.0 0.2 3.6 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) Pkinase PF00069.25 ETS83480.1 - 1.4e-62 211.4 0.0 2e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS83480.1 - 7.7e-45 153.2 0.0 1.1e-44 152.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS83480.1 - 2.6e-07 30.2 0.0 7.6e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ETS83480.1 - 0.0021 16.9 0.2 0.0046 15.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 ETS83480.1 - 0.023 14.1 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ETS83480.1 - 0.083 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cyt-b5 PF00173.28 ETS83483.1 - 3.4e-24 84.8 4.0 7.9e-13 48.4 0.0 4.9 5 0 0 5 5 5 3 Cytochrome b5-like Heme/Steroid binding domain Glyco_hydro_5_C PF18564.1 ETS83484.1 - 1.1e-23 83.6 0.3 3.1e-23 82.1 0.1 1.9 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 ETS83484.1 - 8.3e-12 45.1 1.9 2.2e-07 30.6 0.3 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) TPR_2 PF07719.17 ETS83485.1 - 3.3e-27 92.4 41.0 0.0071 16.4 0.2 15.9 16 0 0 16 16 16 8 Tetratricopeptide repeat TPR_16 PF13432.6 ETS83485.1 - 2.9e-25 88.6 21.7 8.4e-05 23.1 0.0 11.6 10 1 1 11 11 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 ETS83485.1 - 6.8e-24 84.2 12.1 0.00059 20.3 0.4 9.7 7 2 2 9 9 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 ETS83485.1 - 5.7e-23 79.7 30.0 0.003 17.3 0.0 14.6 16 0 0 16 16 14 5 Tetratricopeptide repeat TPR_14 PF13428.6 ETS83485.1 - 1.8e-19 68.7 20.4 0.0064 17.2 0.0 14.0 10 4 5 15 15 15 2 Tetratricopeptide repeat TPR_8 PF13181.6 ETS83485.1 - 3e-17 61.3 37.8 0.12 12.7 0.0 15.0 17 0 0 17 17 15 5 Tetratricopeptide repeat TPR_11 PF13414.6 ETS83485.1 - 9.8e-17 60.4 22.5 0.019 14.7 0.0 10.6 11 1 0 11 11 11 6 TPR repeat TPR_17 PF13431.6 ETS83485.1 - 3e-16 58.5 15.8 0.63 10.6 0.0 13.3 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_12 PF13424.6 ETS83485.1 - 6.9e-11 42.3 45.3 0.31 11.4 0.1 13.5 12 4 2 14 14 12 6 Tetratricopeptide repeat TPR_9 PF13371.6 ETS83485.1 - 2.7e-10 40.2 2.5 0.28 11.4 0.5 7.1 6 2 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 ETS83485.1 - 1.6e-09 37.1 21.0 0.59 10.3 0.1 12.1 13 0 0 13 13 13 3 Tetratricopeptide repeat TPR_22 PF18833.1 ETS83485.1 - 1.5e-07 31.5 0.0 1.1e-06 28.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS83485.1 - 7.5e-06 26.1 23.0 0.18 12.1 0.1 8.3 7 2 3 10 10 9 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ETS83485.1 - 8.5e-06 26.1 26.4 0.13 12.9 0.0 11.7 14 0 0 14 14 10 1 Tetratricopeptide repeat HemY_N PF07219.13 ETS83485.1 - 6.3e-05 23.1 1.1 1.2 9.4 0.0 5.2 3 1 1 4 4 4 1 HemY protein N-terminus TPR_20 PF14561.6 ETS83485.1 - 0.0022 18.3 11.5 8.8 6.7 0.1 6.2 6 1 1 7 7 5 0 Tetratricopeptide repeat DUF5588 PF17826.1 ETS83485.1 - 0.0034 16.3 0.2 2.2 7.1 0.0 2.5 2 0 0 2 2 2 2 Family of unknown function (DUF5588) DUF4919 PF16266.5 ETS83485.1 - 0.0047 16.9 0.1 0.23 11.4 0.1 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4919) Coatomer_WDAD PF04053.14 ETS83485.1 - 0.0064 15.6 0.1 0.02 13.9 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region RPN7 PF10602.9 ETS83485.1 - 0.028 14.1 2.2 0.63 9.7 0.1 3.7 4 1 0 4 4 3 0 26S proteasome subunit RPN7 NRBF2_MIT PF17169.4 ETS83485.1 - 0.091 13.0 0.0 0.56 10.5 0.0 2.4 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 FAT PF02259.23 ETS83485.1 - 0.28 10.4 8.3 6.5 5.9 0.0 4.7 5 1 0 6 6 6 0 FAT domain TPR_10 PF13374.6 ETS83485.1 - 8.3 6.4 29.0 2.5 8.1 0.1 9.2 11 0 0 11 11 8 0 Tetratricopeptide repeat Tannase PF07519.11 ETS83486.1 - 5.7e-105 351.9 0.2 6.8e-105 351.7 0.2 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 ETS83486.1 - 6.6e-06 25.7 0.4 0.083 12.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ETS83486.1 - 0.0079 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS83486.1 - 0.085 12.1 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 NAD_binding_10 PF13460.6 ETS83487.1 - 1.1e-14 54.8 0.0 1.4e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS83487.1 - 0.0017 18.0 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 ETS83487.1 - 0.0081 16.4 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Lipase_GDSL PF00657.22 ETS83488.1 - 6.2e-07 29.6 0.1 8.4e-07 29.2 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ETS83488.1 - 0.0035 17.8 1.0 0.054 13.9 1.0 2.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family adh_short PF00106.25 ETS83494.1 - 5.6e-31 107.5 3.1 7.3e-31 107.1 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS83494.1 - 3.8e-26 92.1 0.4 5e-26 91.7 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS83494.1 - 1.5e-09 38.1 0.4 2.1e-09 37.6 0.4 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS83494.1 - 0.0034 16.5 0.1 0.0047 16.1 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 ETS83494.1 - 0.0067 15.9 0.0 0.053 13.0 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4263 PF14082.6 ETS83494.1 - 0.15 12.3 0.0 4.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4263) zf-MYND PF01753.18 ETS83495.1 - 4.7e-10 39.4 14.3 8.2e-10 38.6 14.3 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ETS83495.1 - 0.0023 18.2 8.4 0.0025 18.1 7.5 1.5 1 1 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding FAD_binding_4 PF01565.23 ETS83497.1 - 1.6e-23 83.0 1.0 3e-23 82.1 1.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS83497.1 - 0.00022 21.2 1.9 0.0003 20.8 0.0 2.2 2 0 0 2 2 2 1 Berberine and berberine like SeqA PF03925.13 ETS83498.1 - 0.13 12.2 3.6 6 6.9 1.0 2.6 2 0 0 2 2 2 0 SeqA protein C-terminal domain SesA PF17107.5 ETS83498.1 - 3 8.0 8.3 4.2 7.6 0.1 3.1 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA PF00004.29 ETS83499.1 - 3.8e-16 59.7 0.0 8.9e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS83499.1 - 3.2e-05 24.4 0.2 9.8e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain SR-25 PF10500.9 ETS83499.1 - 0.0019 17.8 29.0 0.0019 17.8 29.0 5.1 3 1 2 5 5 5 1 Nuclear RNA-splicing-associated protein AAA_5 PF07728.14 ETS83499.1 - 0.002 18.1 0.0 0.0045 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Coilin_N PF15862.5 ETS83499.1 - 0.0027 17.5 3.6 0.0027 17.5 3.6 6.0 4 1 1 6 6 6 1 Coilin N-terminus AAA_22 PF13401.6 ETS83499.1 - 0.013 15.8 0.2 0.055 13.7 0.1 2.1 1 1 1 2 2 2 0 AAA domain Pkinase PF00069.25 ETS83500.1 - 1e-70 238.1 0.0 1.3e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS83500.1 - 6.3e-34 117.4 0.0 8.7e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ETS83500.1 - 1.5e-11 44.8 1.3 1.5e-11 44.8 1.3 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 ETS83500.1 - 5.9e-07 28.8 0.0 8.5e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 ETS83500.1 - 0.00083 19.6 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 ETS83500.1 - 0.02 14.2 0.0 0.047 13.0 0.0 1.5 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 ETS83500.1 - 0.072 12.7 0.1 0.61 9.7 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Peptidase_S9 PF00326.21 ETS83501.1 - 2.9e-40 138.0 0.9 2.9e-40 138.0 0.9 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 ETS83501.1 - 0.00058 18.7 1.0 0.0065 15.3 0.0 2.8 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 ETS83501.1 - 0.0045 16.9 2.9 8.3 6.5 0.1 4.2 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat MFS_1 PF07690.16 ETS83502.1 - 0.00061 18.8 44.1 0.00061 18.8 44.1 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily Tannase PF07519.11 ETS83503.1 - 6.5e-102 341.9 3.6 9.9e-102 341.2 3.6 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase Sulfatase PF00884.23 ETS83504.1 - 1.4e-62 211.9 1.1 1.9e-62 211.4 1.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 ETS83504.1 - 0.011 15.4 1.0 0.1 12.2 1.0 2.1 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 ETS83504.1 - 0.055 12.1 0.0 0.099 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DAPG_hydrolase PF18089.1 ETS83505.1 - 2.8e-09 36.9 6.0 4.3e-09 36.2 6.0 1.4 1 1 0 1 1 1 1 DAPG hydrolase PhiG domain Vps62 PF06101.11 ETS83506.1 - 4.3e-10 38.5 1.0 4.9e-10 38.3 0.2 1.4 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 F-box-like PF12937.7 ETS83506.1 - 2.4e-07 30.5 0.0 7.4e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS83506.1 - 0.00014 21.7 0.1 0.00056 19.7 0.0 2.1 2 0 0 2 2 2 1 F-box domain Amidase PF01425.21 ETS83507.1 - 1.2e-31 110.2 2.5 1.9e-31 109.6 2.5 1.2 1 0 0 1 1 1 1 Amidase COesterase PF00135.28 ETS83509.1 - 8.7e-65 219.5 1.0 1.3e-59 202.5 2.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS83509.1 - 5e-06 26.5 0.2 1.1e-05 25.5 0.2 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold 4HBT_3 PF13622.6 ETS83510.1 - 2.4e-33 116.4 0.1 2.8e-33 116.2 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily HET PF06985.11 ETS83511.1 - 1.5e-35 122.7 0.2 1.5e-35 122.7 0.2 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AbiGi PF10899.8 ETS83511.1 - 0.069 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative abortive phage resistance protein AbiGi, antitoxin Pigment_DH PF06324.11 ETS83511.1 - 0.18 11.9 0.0 0.46 10.7 0.0 1.6 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) Lipocalin_2 PF08212.12 ETS83513.1 - 1.6e-21 76.8 0.0 1.9e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain UPF0121 PF03661.13 ETS83514.1 - 7.5e-29 100.8 2.6 9.9e-29 100.4 2.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DSPc PF00782.20 ETS83515.1 - 2.8e-07 30.4 0.0 5.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ETS83515.1 - 0.00036 20.2 0.0 0.0011 18.6 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 ETS83515.1 - 0.0064 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PhyH PF05721.13 ETS83516.1 - 1e-07 32.5 0.0 4.3e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 ETS83516.1 - 0.024 15.0 0.0 0.043 14.2 0.0 1.4 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF3712 PF12505.8 ETS83517.1 - 3.6e-25 88.6 2.3 9.1e-25 87.3 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) DUF1772 PF08592.11 ETS83517.1 - 0.063 13.6 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) LEA_2 PF03168.13 ETS83517.1 - 0.084 13.4 0.1 0.28 11.8 0.0 1.9 2 0 0 2 2 2 0 Late embryogenesis abundant protein LIN52 PF10044.9 ETS83518.1 - 3.1e-10 40.6 0.3 0.043 14.5 0.0 8.4 3 1 7 11 11 11 2 Retinal tissue protein DUF3375 PF11855.8 ETS83518.1 - 0.025 13.5 0.2 3.5 6.5 0.0 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3375) FlgN PF05130.12 ETS83518.1 - 0.28 11.7 18.6 1.4 9.4 0.1 6.4 3 1 2 7 7 7 0 FlgN protein Antimicrobial_7 PF08102.11 ETS83518.1 - 2.5 8.4 7.0 1e+02 3.3 0.0 5.3 7 0 0 7 7 7 0 Scorpion antimicrobial peptide YlbD_coat PF14071.6 ETS83518.1 - 5 7.4 14.8 1.4e+02 2.7 0.0 7.5 8 1 1 9 9 9 0 Putative coat protein MobC PF05713.11 ETS83518.1 - 8.2 7.0 7.8 89 3.7 0.1 5.5 6 1 0 6 6 6 0 Bacterial mobilisation protein (MobC) DUF3712 PF12505.8 ETS83519.1 - 0.052 13.8 0.0 0.059 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3712) FAD_binding_3 PF01494.19 ETS83520.1 - 8.6e-12 45.0 0.2 1.5e-10 40.9 0.2 2.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ETS83520.1 - 3.2e-06 27.3 0.1 1.1e-05 25.6 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS83520.1 - 0.00049 19.3 0.0 0.00089 18.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS83520.1 - 0.0036 16.9 0.5 0.063 12.8 0.1 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS83520.1 - 0.0057 15.9 0.2 0.034 13.4 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS83520.1 - 0.082 13.5 0.1 0.68 10.5 0.0 2.6 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS83520.1 - 0.095 11.7 0.1 1 8.4 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ETS83520.1 - 0.14 11.4 0.0 0.44 9.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SSF PF00474.17 ETS83521.1 - 3.5e-23 82.1 32.7 5.4e-23 81.5 32.7 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family NAD_binding_4 PF07993.12 ETS83522.1 - 1.3e-36 126.1 0.0 2.1e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 ETS83522.1 - 5.9e-28 97.6 0.0 1.3e-27 96.4 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 ETS83522.1 - 7e-11 42.0 0.0 1.4e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS83522.1 - 4.1e-05 23.1 0.0 6.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase PP-binding PF00550.25 ETS83522.1 - 0.00013 22.3 0.1 0.00032 21.0 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 ETS83522.1 - 0.024 14.5 0.2 0.093 12.6 0.2 2.0 1 1 0 1 1 1 0 KR domain Dynamin_N PF00350.23 ETS83523.1 - 8.8e-39 133.3 0.0 1.8e-38 132.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 ETS83523.1 - 2.3e-27 96.0 0.0 3.5e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 ETS83523.1 - 2e-05 24.6 0.0 0.00061 19.9 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 ETS83523.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 ETS83523.1 - 0.13 12.8 0.1 1.3 9.6 0.0 2.6 3 0 0 3 3 3 0 ABC transporter AAA_23 PF13476.6 ETS83523.1 - 0.16 12.5 0.3 3.1 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain DIOX_N PF14226.6 ETS83524.1 - 1.7e-16 61.0 0.0 3.4e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS83524.1 - 1.2e-14 54.6 0.0 2.1e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DLH PF01738.18 ETS83525.1 - 1.4e-25 90.2 0.0 1.8e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ETS83525.1 - 0.01 15.5 0.0 0.031 13.9 0.0 1.7 2 1 0 2 2 2 0 alpha/beta hydrolase fold ADH_N PF08240.12 ETS83527.1 - 3.1e-23 81.7 3.9 5.4e-23 81.0 3.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS83527.1 - 3.2e-16 59.5 0.1 5.7e-16 58.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ETS83527.1 - 7.1e-05 22.2 0.1 0.00011 21.6 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 ETS83527.1 - 0.006 16.3 0.2 0.0095 15.7 0.2 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_zinc_N_2 PF13602.6 ETS83527.1 - 0.0075 17.3 0.1 0.035 15.1 0.1 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Sugar_tr PF00083.24 ETS83528.1 - 8.4e-131 436.9 21.2 9.7e-131 436.7 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS83528.1 - 7.7e-29 100.7 38.2 5.2e-22 78.2 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YqfD PF06898.11 ETS83528.1 - 0.61 8.9 1.7 6.9 5.4 0.0 2.2 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD VEGFR-2_TMD PF17988.1 ETS83528.1 - 3.1 7.3 9.8 3.3 7.2 3.4 2.9 2 0 0 2 2 2 0 VEGFR-2 Transmembrane domain VIT PF08487.10 ETS83529.1 - 5.7e-29 100.6 0.0 1.1e-28 99.6 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 ETS83529.1 - 4.7e-21 75.3 0.0 9e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 ETS83529.1 - 7.5e-12 45.9 0.1 1.8e-11 44.6 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 ETS83529.1 - 7e-09 36.2 0.0 1.6e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 ETS83529.1 - 4.4e-07 29.7 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain INTS5_N PF14837.6 ETS83531.1 - 0.028 14.0 0.1 0.051 13.2 0.1 1.4 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus zinc_ribbon_10 PF10058.9 ETS83531.1 - 0.082 12.6 0.9 0.25 11.1 0.5 1.9 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein GrpE PF01025.19 ETS83531.1 - 0.11 12.1 0.6 0.25 11.0 0.6 1.6 1 1 0 1 1 1 0 GrpE Peptidase_S8 PF00082.22 ETS83532.1 - 5.9e-15 55.3 0.3 5.5e-14 52.1 0.3 2.3 1 1 0 1 1 1 1 Subtilase family adh_short_C2 PF13561.6 ETS83534.1 - 1.9e-55 188.0 0.6 2.4e-55 187.6 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS83534.1 - 2.4e-44 151.1 0.3 3.2e-44 150.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS83534.1 - 4e-11 43.2 1.0 1.1e-10 41.7 1.0 1.7 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 ETS83534.1 - 0.038 13.3 0.1 0.18 11.1 0.0 1.9 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HATPase_c PF02518.26 ETS83534.1 - 0.045 14.3 0.0 3.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NAD_binding_2 PF03446.15 ETS83534.1 - 0.045 13.9 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AIRC PF00731.20 ETS83534.1 - 0.11 12.1 1.5 0.22 11.1 0.3 2.1 3 0 0 3 3 3 0 AIR carboxylase DUF1697 PF08002.11 ETS83534.1 - 0.12 12.9 0.3 0.97 9.9 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1697) ADH_N PF08240.12 ETS83535.1 - 2.3e-32 111.1 0.9 2.3e-32 111.1 0.9 2.4 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS83535.1 - 2.1e-23 82.7 0.4 4.4e-23 81.7 0.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS83535.1 - 3e-07 30.2 0.4 7.2e-06 25.6 0.4 2.2 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ETS83535.1 - 6.5e-05 24.0 0.1 0.00028 22.0 0.1 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase CMAS PF02353.20 ETS83535.1 - 0.0022 17.3 0.0 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ETS83535.1 - 0.0046 17.6 0.1 0.01 16.5 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.19 ETS83535.1 - 0.042 13.2 0.2 0.072 12.5 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 ETS83535.1 - 0.09 13.4 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PRK PF00485.18 ETS83536.1 - 1.2e-05 25.1 0.0 1.6e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 ETS83536.1 - 0.00011 22.8 0.0 0.00022 21.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ETS83536.1 - 0.00058 20.0 0.0 0.041 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ETS83536.1 - 0.0011 19.4 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 ETS83536.1 - 0.0012 17.9 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 ETS83536.1 - 0.0042 16.3 0.0 0.0067 15.6 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.12 ETS83536.1 - 0.0052 16.1 0.0 0.012 14.9 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.15 ETS83536.1 - 0.017 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_17 PF13207.6 ETS83536.1 - 0.02 15.3 0.0 0.18 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ETS83536.1 - 0.027 14.9 0.0 0.053 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 ETS83536.1 - 0.028 14.9 0.0 0.045 14.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 ETS83536.1 - 0.031 14.0 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ETS83536.1 - 0.037 13.6 0.1 0.1 12.1 0.1 1.6 1 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 ETS83536.1 - 0.042 12.9 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KAP_NTPase PF07693.14 ETS83536.1 - 0.047 12.9 0.0 0.051 12.8 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Mg_chelatase PF01078.21 ETS83536.1 - 0.051 13.0 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 ETS83536.1 - 0.055 13.3 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 ETS83536.1 - 0.059 13.6 0.0 0.1 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 ETS83536.1 - 0.062 12.9 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 ETS83536.1 - 0.066 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase KTI12 PF08433.10 ETS83536.1 - 0.075 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.14 ETS83536.1 - 0.084 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 ETS83536.1 - 0.12 12.0 0.1 0.21 11.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ETS83536.1 - 0.13 12.0 0.6 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain APS_kinase PF01583.20 ETS83536.1 - 0.14 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.12 ETS83536.1 - 0.18 11.7 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Cytidylate_kin PF02224.18 ETS83536.1 - 0.18 11.5 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 Cytidylate kinase Zot PF05707.12 ETS83536.1 - 0.2 11.2 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) adh_short_C2 PF13561.6 ETS83537.1 - 8.7e-59 198.9 0.7 1e-58 198.7 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS83537.1 - 1e-43 149.1 0.5 1.3e-43 148.8 0.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS83537.1 - 8.5e-14 51.9 2.0 1.3e-13 51.2 2.0 1.3 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ETS83537.1 - 3.6e-05 24.0 0.3 7.3e-05 23.0 0.3 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ETS83537.1 - 0.00094 18.7 0.4 0.0013 18.3 0.4 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS83537.1 - 0.0016 17.9 0.1 0.0031 17.0 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 ETS83537.1 - 0.0038 16.6 0.2 0.0073 15.7 0.1 1.5 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ub-RnfH PF03658.14 ETS83537.1 - 0.012 15.9 0.3 0.025 15.0 0.3 1.4 1 0 0 1 1 1 0 RnfH family Ubiquitin Polysacc_synt_2 PF02719.15 ETS83537.1 - 0.014 14.6 0.0 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.6 ETS83537.1 - 0.042 14.3 0.2 0.08 13.4 0.2 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 ETS83537.1 - 0.052 13.4 0.5 0.085 12.7 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_99 PF16317.5 ETS83537.1 - 0.096 11.8 0.1 0.25 10.4 0.0 1.8 2 1 0 2 2 2 0 Glycosyl hydrolase family 99 NAD_binding_2 PF03446.15 ETS83537.1 - 0.1 12.7 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 ETS83537.1 - 0.12 12.5 0.1 0.27 11.3 0.1 1.6 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.24 ETS83538.1 - 6.3e-90 302.2 22.8 7.3e-90 302.0 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS83538.1 - 9.1e-29 100.5 28.7 1.5e-26 93.2 20.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 ETS83539.1 - 1.5e-19 70.1 0.1 2.5e-19 69.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS83539.1 - 5.9e-07 29.5 11.0 9.5e-07 28.8 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 ETS83539.1 - 0.015 15.5 4.1 0.029 14.5 4.1 1.4 1 0 0 1 1 1 0 Gal4-like dimerisation domain Aconitase PF00330.20 ETS83539.1 - 0.089 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) AltA1 PF16541.5 ETS83540.1 - 0.015 16.1 0.2 0.021 15.7 0.2 1.3 1 0 0 1 1 1 0 Alternaria alternata allergen 1 dbPDZ_assoc PF16610.5 ETS83540.1 - 0.77 10.0 5.5 3.3 8.0 5.4 1.9 1 1 1 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 HsbA PF12296.8 ETS83541.1 - 3.3e-16 59.8 10.2 3.5e-16 59.7 9.1 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A ATG16 PF08614.11 ETS83542.1 - 0.00013 22.3 2.0 0.00026 21.3 2.0 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) UPF0231 PF06062.11 ETS83542.1 - 0.02 15.2 2.2 0.036 14.3 2.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0231) TMF_TATA_bd PF12325.8 ETS83542.1 - 0.027 14.7 7.0 0.056 13.7 7.0 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4201 PF13870.6 ETS83542.1 - 0.031 14.0 8.0 0.067 12.9 7.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Fez1 PF06818.15 ETS83542.1 - 0.033 14.6 5.7 0.057 13.9 5.7 1.4 1 0 0 1 1 1 0 Fez1 TMPIT PF07851.13 ETS83542.1 - 0.077 12.2 3.4 0.14 11.4 3.4 1.4 1 0 0 1 1 1 0 TMPIT-like protein YabA PF06156.13 ETS83542.1 - 0.18 12.5 3.5 0.41 11.3 3.5 1.7 1 0 0 1 1 1 0 Initiation control protein YabA DUF16 PF01519.16 ETS83542.1 - 0.78 10.3 3.6 1.9 9.0 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 Snapin_Pallidin PF14712.6 ETS83542.1 - 0.93 10.0 7.6 4.1 7.9 7.4 2.1 1 1 1 2 2 2 0 Snapin/Pallidin Spc7 PF08317.11 ETS83542.1 - 0.99 8.2 10.5 0.78 8.6 9.2 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein ZapB PF06005.12 ETS83542.1 - 1.5 9.3 9.8 0.54 10.7 5.6 2.3 1 1 1 2 2 2 0 Cell division protein ZapB XhlA PF10779.9 ETS83542.1 - 2.7 8.3 7.8 7.7 6.8 1.4 3.4 3 1 1 4 4 4 0 Haemolysin XhlA Thioredoxin PF00085.20 ETS83543.1 - 5.8e-23 80.8 0.0 7.8e-23 80.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 ETS83543.1 - 1.1e-06 28.2 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 ETS83543.1 - 5.9e-06 26.7 0.1 2.1e-05 24.9 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 ETS83543.1 - 1.6e-05 24.8 0.0 7.7e-05 22.6 0.0 1.8 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.6 ETS83543.1 - 4.9e-05 23.4 0.1 7.7e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 ETS83543.1 - 0.00015 22.0 0.0 0.0023 18.2 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 ETS83543.1 - 0.00018 21.3 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin TraF PF13728.6 ETS83543.1 - 0.00074 19.4 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 ETS83543.1 - 0.0072 16.1 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 ETS83543.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.7 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 ETS83543.1 - 0.21 11.2 0.0 0.52 10.0 0.0 1.7 1 1 1 2 2 2 0 Thioredoxin HET PF06985.11 ETS83544.1 - 1.8e-20 73.8 7.5 5.4e-20 72.2 7.5 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 ETS83545.1 - 6.6e-30 104.2 26.4 7.5e-30 104.0 25.2 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.25 ETS83549.1 - 3.9e-36 124.4 0.1 6.9e-36 123.5 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS83549.1 - 9.3e-23 81.0 0.3 1.3e-22 80.5 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS83549.1 - 7.7e-06 25.9 0.2 0.00014 21.8 0.2 2.1 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 ETS83549.1 - 0.0067 16.2 0.2 0.019 14.7 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.19 ETS83549.1 - 0.081 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.6 ETS83549.1 - 0.13 13.0 0.0 0.28 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Podoplanin PF05808.11 ETS83550.1 - 9.3e-08 32.3 3.4 1.5e-07 31.7 3.4 1.4 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 ETS83550.1 - 0.0044 16.9 0.0 0.0076 16.2 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Rax2 PF12768.7 ETS83550.1 - 0.0078 15.7 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity CD99L2 PF12301.8 ETS83550.1 - 0.0085 16.4 0.2 0.013 15.8 0.2 1.3 1 0 0 1 1 1 1 CD99 antigen like protein 2 SKG6 PF08693.10 ETS83550.1 - 0.022 14.2 1.5 0.022 14.2 1.5 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain adh_short PF00106.25 ETS83551.1 - 2.8e-25 88.9 0.0 3.6e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS83551.1 - 3.7e-17 62.7 0.0 4.9e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS83551.1 - 1.1e-07 32.0 0.0 1.4e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS83551.1 - 0.00037 20.0 0.2 0.00096 18.7 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS83551.1 - 0.0011 18.9 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 ETS83552.1 - 4.3e-06 26.7 0.0 7.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS83552.1 - 4.6e-05 23.3 0.0 0.00032 20.5 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ETS83552.1 - 0.0064 17.6 0.0 0.013 16.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RRM_1 PF00076.22 ETS83554.1 - 2e-08 33.9 1.2 9.1e-08 31.8 0.1 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 ETS83554.1 - 1.2e-07 31.9 0.0 2.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 PWI domain zf_CCCH_4 PF18345.1 ETS83554.1 - 0.0015 18.5 3.3 0.0028 17.7 3.3 1.4 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM_2 PF14605.6 ETS83554.1 - 0.0018 18.2 0.0 0.061 13.3 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 ETS83554.1 - 0.013 15.4 5.4 0.022 14.7 5.4 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WSD PF15613.6 ETS83554.1 - 0.019 15.5 2.8 0.05 14.1 2.8 1.7 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif zf-CCCH_4 PF18044.1 ETS83554.1 - 0.26 11.1 3.0 0.47 10.3 3.0 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger HAUS-augmin3 PF14932.6 ETS83554.1 - 0.45 10.0 12.5 0.52 9.9 11.5 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Borrelia_P83 PF05262.11 ETS83554.1 - 1.3 7.4 9.7 2.2 6.7 9.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.6 ETS83554.1 - 3.1 7.1 6.6 0.7 9.2 2.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PHP PF02811.19 ETS83555.1 - 9.9e-11 42.2 0.0 2.9e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 PHP domain MTHFR PF02219.17 ETS83556.1 - 1.2e-113 379.2 0.0 1.9e-113 378.6 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase bZIP_2 PF07716.15 ETS83557.1 - 0.065 13.3 4.0 0.11 12.6 4.0 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DEAD PF00270.29 ETS83558.1 - 1.8e-25 89.7 0.0 3e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 ETS83558.1 - 8.2e-22 77.8 0.2 2.1e-21 76.4 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 ETS83558.1 - 2.4e-13 50.4 0.1 1.3e-12 48.0 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS83558.1 - 6.3e-06 26.3 0.0 1.1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 ETS83558.1 - 0.00074 19.9 0.0 0.0015 18.9 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like Kinesin PF00225.23 ETS83559.1 - 1.8e-45 155.3 0.0 6.9e-45 153.4 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ETS83559.1 - 1e-22 80.7 0.0 2e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Spc7 PF08317.11 ETS83559.1 - 0.0014 17.6 12.3 0.0029 16.5 12.3 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF812 PF05667.11 ETS83559.1 - 0.0028 16.6 14.5 0.0043 16.0 14.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) AAA_24 PF13479.6 ETS83559.1 - 0.03 14.0 1.1 0.79 9.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ETS83559.1 - 0.04 14.3 0.0 0.04 14.3 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain SesA PF17107.5 ETS83559.1 - 0.12 12.6 3.0 0.11 12.7 1.2 1.9 2 0 0 2 2 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases YkyA PF10368.9 ETS83559.1 - 0.2 11.3 16.1 0.017 14.8 11.0 1.7 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Exonuc_VII_L PF02601.15 ETS83559.1 - 0.27 10.8 10.9 0.12 11.9 8.6 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit Rootletin PF15035.6 ETS83559.1 - 0.28 11.2 16.4 0.51 10.3 16.4 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ADIP PF11559.8 ETS83559.1 - 0.3 11.2 12.3 0.7 10.0 12.3 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ABC_tran PF00005.27 ETS83559.1 - 0.85 10.1 5.3 1.3 9.5 0.0 2.8 2 1 1 3 3 3 0 ABC transporter GAS PF13851.6 ETS83559.1 - 1.4 8.3 18.8 2.9 7.2 13.9 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding BST2 PF16716.5 ETS83559.1 - 1.8 9.2 9.6 0.7 10.5 4.6 2.7 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 ERM PF00769.19 ETS83559.1 - 2.7 7.7 26.0 3.5 7.4 16.6 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Atg14 PF10186.9 ETS83559.1 - 5.1 6.1 15.5 12 4.8 15.5 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 ETS83559.1 - 6.4 6.0 15.0 11 5.2 15.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 ETS83559.1 - 6.7 6.8 5.6 2.3 8.3 1.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.14 ETS83559.1 - 6.8 7.0 23.0 5.8 7.3 12.1 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FMN_bind_2 PF04299.12 ETS83560.1 - 1.7e-55 187.3 0.1 2.2e-55 186.9 0.1 1.2 1 0 0 1 1 1 1 Putative FMN-binding domain GFA PF04828.14 ETS83561.1 - 1.6e-09 37.9 1.3 2.7e-09 37.2 1.3 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme adh_short_C2 PF13561.6 ETS83562.1 - 7.9e-53 179.4 2.2 9.2e-53 179.2 2.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS83562.1 - 5.7e-41 140.1 0.3 7.4e-41 139.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 ETS83562.1 - 6.3e-08 32.4 0.3 7.1e-07 28.9 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fer4_21 PF14697.6 ETS83563.1 - 0.11 12.6 0.2 0.23 11.6 0.2 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Metallophos PF00149.28 ETS83564.1 - 7.8e-37 127.8 0.4 1e-36 127.4 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ETS83564.1 - 0.15 12.3 0.0 0.19 11.9 0.0 1.4 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Rho_GDI PF02115.17 ETS83565.1 - 2.6e-65 219.9 1.4 2.8e-65 219.7 1.4 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor KilA-N PF04383.13 ETS83566.1 - 0.005 16.7 0.0 0.03 14.2 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain AA_permease_2 PF13520.6 ETS83567.1 - 3e-49 168.0 47.3 3.8e-49 167.7 47.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS83567.1 - 4.8e-24 84.8 39.0 6.3e-24 84.4 39.0 1.1 1 0 0 1 1 1 1 Amino acid permease Colicin_Pyocin PF01320.18 ETS83569.1 - 0.082 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein TRI12 PF06609.13 ETS83571.1 - 1.7e-24 86.2 25.6 2.2e-24 85.8 25.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ETS83571.1 - 1e-20 74.0 79.6 9.9e-20 70.7 54.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3270 PF11674.8 ETS83571.1 - 1 9.6 0.0 1 9.6 0.0 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3270) GFA PF04828.14 ETS83572.1 - 4.3e-11 43.0 0.2 4.3e-11 43.0 0.2 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme NAD_binding_2 PF03446.15 ETS83574.1 - 1.5e-40 138.9 0.1 2.4e-40 138.3 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ETS83574.1 - 2e-28 99.1 0.1 5.1e-28 97.8 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ETS83574.1 - 1.5e-07 31.9 0.0 4.6e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 ETS83574.1 - 2.3e-05 23.5 0.0 3.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 ETS83574.1 - 0.0017 19.2 0.0 0.0078 17.0 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 ETS83574.1 - 0.04 14.0 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 ETS83574.1 - 0.046 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain RTA1 PF04479.13 ETS83575.1 - 2.9e-61 206.7 2.6 2.9e-61 206.7 2.6 1.8 2 0 0 2 2 2 1 RTA1 like protein DUF4233 PF14017.6 ETS83575.1 - 0.39 11.1 6.4 1.8 8.9 0.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) Adaptin_N PF01602.20 ETS83576.1 - 1.7e-101 340.4 0.2 2e-101 340.1 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ETS83576.1 - 2.2e-15 57.1 0.1 6.7e-14 52.2 0.0 2.9 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ETS83576.1 - 2.4e-11 42.9 0.2 0.044 14.1 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 ETS83576.1 - 3.5e-10 40.1 4.8 3.9e-05 24.0 0.0 4.7 3 2 2 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 ETS83576.1 - 0.0011 19.4 1.5 1.5 9.4 0.0 4.6 5 0 0 5 5 4 1 HEAT-like repeat Cohesin_HEAT PF12765.7 ETS83576.1 - 0.0055 17.0 3.8 0.24 11.8 0.0 4.0 5 0 0 5 5 5 1 HEAT repeat associated with sister chromatid cohesion CLASP_N PF12348.8 ETS83576.1 - 0.042 13.4 0.1 20 4.7 0.0 3.1 3 0 0 3 3 3 0 CLASP N terminal VHS PF00790.19 ETS83576.1 - 0.13 12.1 1.8 31 4.4 0.0 3.7 4 0 0 4 4 4 0 VHS domain CRISPR_Cse2 PF09485.10 ETS83576.1 - 0.57 10.7 3.9 27 5.3 0.2 3.5 4 2 0 4 4 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) RNA_pol_Rpc4 PF05132.14 ETS83576.1 - 2.8 8.4 6.0 7 7.1 6.0 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 SDA1 PF05285.12 ETS83576.1 - 3.1 7.1 30.8 4.6 6.6 30.8 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 ETS83576.1 - 5 5.2 32.9 5 5.2 31.8 1.5 2 0 0 2 2 2 0 Nop14-like family Pox_Ag35 PF03286.14 ETS83576.1 - 8.1 6.2 15.3 27 4.5 15.3 2.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nuf2 PF03800.14 ETS83577.1 - 1e-43 148.8 0.1 3.1e-43 147.2 0.1 1.9 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 ETS83577.1 - 1.7e-35 121.6 23.0 1.7e-35 121.6 23.0 3.9 3 1 0 3 3 3 1 Designed helical repeat protein 10 domain DUF4407 PF14362.6 ETS83577.1 - 6.1 6.1 48.4 0.91 8.8 21.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Bacillus_HBL PF05791.11 ETS83577.1 - 8.4 6.2 22.7 0.14 11.9 3.0 3.6 2 2 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Thioredoxin PF00085.20 ETS83579.1 - 2e-26 92.0 0.1 2.2e-26 91.8 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 ETS83579.1 - 1.3e-06 28.0 0.0 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 ETS83579.1 - 2.4e-06 27.9 0.2 1.3e-05 25.6 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ETS83579.1 - 1.7e-05 25.0 0.0 0.00019 21.7 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 ETS83579.1 - 0.00016 21.8 0.1 0.0002 21.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 ETS83579.1 - 0.00052 20.2 0.0 0.001 19.2 0.0 1.5 1 1 0 1 1 1 1 Glutaredoxin Redoxin PF08534.10 ETS83579.1 - 0.0017 18.1 0.1 0.0039 16.9 0.1 1.6 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ETS83579.1 - 0.0033 17.3 0.0 0.0037 17.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 ETS83579.1 - 0.023 14.4 0.0 0.028 14.2 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin OPT PF03169.15 ETS83580.1 - 1.3e-163 545.9 55.0 1.5e-163 545.8 55.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SLAC1 PF03595.17 ETS83581.1 - 2.6e-65 220.8 50.0 3e-65 220.6 50.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Amelotin PF15757.5 ETS83581.1 - 0.033 13.8 0.7 0.048 13.2 0.1 1.5 2 0 0 2 2 2 0 Amelotin MMR_HSR1 PF01926.23 ETS83582.1 - 1.8e-09 37.7 0.0 3.8e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 ETS83582.1 - 1.2e-05 24.7 0.0 2.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Septin AIG1 PF04548.16 ETS83582.1 - 0.00036 19.9 0.7 0.01 15.2 0.0 2.3 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 ETS83582.1 - 0.00052 20.0 0.4 0.0016 18.4 0.0 2.0 2 1 1 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 ETS83582.1 - 0.003 18.1 0.6 0.033 14.7 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 ETS83582.1 - 0.037 14.4 4.4 0.098 13.0 0.0 2.8 2 2 0 3 3 3 0 AAA ATPase domain Atg14 PF10186.9 ETS83582.1 - 0.054 12.6 10.5 0.093 11.8 10.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Roc PF08477.13 ETS83582.1 - 0.056 13.7 0.1 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 ETS83582.1 - 0.061 13.4 8.7 0.38 10.8 0.0 3.4 2 2 1 3 3 3 0 Dynamin family Spc7 PF08317.11 ETS83582.1 - 0.069 12.0 12.4 0.1 11.5 12.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Ras PF00071.22 ETS83582.1 - 0.078 12.6 0.1 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 Ras family IIGP PF05049.13 ETS83582.1 - 0.083 11.9 0.0 0.2 10.7 0.0 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 ETS83582.1 - 0.14 12.5 1.4 0.38 11.0 0.0 2.5 2 2 1 3 3 3 0 AAA domain DUF87 PF01935.17 ETS83582.1 - 0.15 12.2 0.1 0.15 12.2 0.1 2.3 2 1 0 2 2 2 0 Helicase HerA, central domain FliD_N PF02465.18 ETS83582.1 - 0.26 12.0 2.3 0.7 10.6 2.3 1.7 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Tmemb_cc2 PF10267.9 ETS83582.1 - 0.27 10.3 12.1 0.5 9.4 12.1 1.4 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein JIP_LZII PF16471.5 ETS83582.1 - 0.53 10.5 6.8 0.065 13.4 1.6 2.1 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II AAA_23 PF13476.6 ETS83582.1 - 0.88 10.0 6.0 13 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain PVL_ORF50 PF07768.11 ETS83582.1 - 8.4 6.7 8.0 21 5.5 7.9 1.7 1 1 0 1 1 1 0 PVL ORF-50-like family MMR_HSR1 PF01926.23 ETS83583.1 - 8.3e-07 29.1 0.0 1.9e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 ETS83583.1 - 0.00035 20.0 0.0 0.00081 18.8 0.0 1.6 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 ETS83583.1 - 0.00066 19.6 1.1 0.002 18.1 0.1 2.2 2 1 0 2 2 2 1 RsgA GTPase Septin PF00735.18 ETS83583.1 - 0.0019 17.5 0.0 0.0058 15.9 0.0 1.8 1 1 0 1 1 1 1 Septin DUF463 PF04317.12 ETS83583.1 - 0.0048 15.9 0.0 0.0084 15.1 0.0 1.4 1 0 0 1 1 1 1 YcjX-like family, DUF463 IIGP PF05049.13 ETS83583.1 - 0.015 14.4 0.2 0.027 13.5 0.0 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_33 PF13671.6 ETS83583.1 - 0.016 15.4 0.3 0.047 13.9 0.1 2.1 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 ETS83583.1 - 0.022 14.8 7.8 1.2 9.2 0.5 3.2 2 2 1 3 3 3 0 Dynamin family AAA_22 PF13401.6 ETS83583.1 - 0.025 14.8 0.2 0.083 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ETS83583.1 - 0.03 14.7 0.2 0.44 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.10 ETS83583.1 - 0.032 13.7 0.3 0.094 12.1 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 ETS83583.1 - 0.052 14.1 0.1 0.25 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ETS83583.1 - 0.062 13.1 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 ETS83583.1 - 0.096 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PPV_E1_C PF00519.17 ETS83583.1 - 0.17 10.7 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase OmpH PF03938.14 ETS83583.1 - 0.34 11.2 6.4 0.69 10.2 6.4 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) adh_short_C2 PF13561.6 ETS83584.1 - 2.4e-56 190.9 0.2 3.6e-56 190.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS83584.1 - 1.1e-47 162.0 2.6 1.4e-47 161.7 2.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS83584.1 - 1.1e-13 51.5 0.6 1.5e-13 51.1 0.6 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 ETS83584.1 - 0.023 14.0 0.1 0.047 13.0 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1372 PF07116.11 ETS83584.1 - 0.052 13.7 0.1 0.11 12.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1372) Dak1_2 PF13684.6 ETS83584.1 - 0.07 12.2 0.1 0.095 11.8 0.1 1.1 1 0 0 1 1 1 0 Dihydroxyacetone kinase family BATS PF06968.13 ETS83585.1 - 1e-23 83.2 0.1 3.8e-23 81.4 0.1 2.1 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 ETS83585.1 - 1.5e-11 45.0 0.1 5.2e-11 43.2 0.1 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Aminotran_1_2 PF00155.21 ETS83586.1 - 9.9e-37 126.9 0.0 1.2e-36 126.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 ETS83586.1 - 0.016 13.9 0.0 0.057 12.1 0.0 1.8 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_3 PF00202.21 ETS83587.1 - 2.9e-35 121.7 0.0 2.2e-17 62.8 0.0 3.1 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 ETS83587.1 - 9.8e-16 58.2 0.0 2.5e-15 56.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain CRAL_TRIO PF00650.20 ETS83588.1 - 2e-23 82.9 0.0 2.9e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ETS83588.1 - 1.6e-09 37.8 0.0 3.4e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Acid_PPase PF12689.7 ETS83589.1 - 1.9e-61 206.8 0.0 2.6e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 Acid Phosphatase LRV PF01816.17 ETS83589.1 - 0.024 15.0 1.4 0.16 12.4 0.2 2.5 2 0 0 2 2 2 0 Leucine rich repeat variant AAA_16 PF13191.6 ETS83590.1 - 1.1e-05 25.9 0.1 3.9e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS83590.1 - 5.6e-05 23.4 0.0 0.0038 17.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF676 PF05057.14 ETS83590.1 - 6e-05 22.6 0.0 0.00063 19.3 0.0 2.6 2 1 0 2 2 2 1 Putative serine esterase (DUF676) NACHT PF05729.12 ETS83590.1 - 0.00023 21.1 0.1 0.00077 19.4 0.0 2.0 2 0 0 2 2 2 1 NACHT domain Abhydrolase_6 PF12697.7 ETS83590.1 - 0.00031 21.4 0.2 0.0009 19.9 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family ATPase_2 PF01637.18 ETS83590.1 - 0.034 14.1 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PGAP1 PF07819.13 ETS83590.1 - 0.074 12.8 0.0 0.2 11.3 0.0 1.7 1 1 0 1 1 1 0 PGAP1-like protein AAA_18 PF13238.6 ETS83590.1 - 0.11 13.1 0.0 0.31 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Glyoxalase PF00903.25 ETS83591.1 - 1e-10 41.9 4.9 2e-06 28.0 2.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CBM_1 PF00734.18 ETS83592.1 - 6.5e-13 48.4 7.1 6.5e-13 48.4 7.1 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain LPMO_10 PF03067.15 ETS83592.1 - 3.2e-10 41.0 0.5 3.2e-10 41.0 0.5 1.8 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading DUF3295 PF11702.8 ETS83592.1 - 0.0021 17.5 14.7 0.0026 17.2 14.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) RXT2_N PF08595.11 ETS83592.1 - 0.094 12.7 2.4 0.18 11.8 2.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 ETS83592.1 - 0.14 10.2 13.0 0.52 8.4 14.1 1.3 2 0 0 2 2 2 0 DNA polymerase phi NOA36 PF06524.12 ETS83592.1 - 0.23 10.8 16.3 0.24 10.7 13.9 2.1 2 0 0 2 2 2 0 NOA36 protein Nop14 PF04147.12 ETS83592.1 - 0.24 9.6 9.3 0.3 9.3 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 ETS83592.1 - 0.29 10.3 8.5 0.43 9.7 8.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.12 ETS83592.1 - 1.8 7.9 11.9 2.4 7.5 11.9 1.1 1 0 0 1 1 1 0 SDA1 RNA_pol_3_Rpc31 PF11705.8 ETS83592.1 - 2.9 8.1 10.4 4.4 7.5 10.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 ETS83592.1 - 4.7 6.9 16.6 7.3 6.2 16.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 ETS83592.1 - 6 6.4 12.1 9.2 5.8 12.1 1.2 1 0 0 1 1 1 0 PPP4R2 Sigma70_ner PF04546.13 ETS83592.1 - 7.6 6.4 7.9 11 5.8 7.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Pkinase PF00069.25 ETS83593.1 - 1.7e-22 80.0 0.0 2.9e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 ETS83593.1 - 6.7e-10 39.4 4.9 1.6e-05 25.6 0.1 4.2 3 0 0 3 3 3 2 WD domain, G-beta repeat HEAT PF02985.22 ETS83593.1 - 2.7e-06 27.2 9.9 0.16 12.3 0.1 6.4 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 ETS83593.1 - 0.00046 20.5 4.4 0.071 13.5 0.1 4.0 2 1 1 3 3 3 1 HEAT repeats Pkinase_Tyr PF07714.17 ETS83593.1 - 0.00046 19.6 0.0 0.00082 18.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 ETS83593.1 - 0.033 14.2 0.5 3.1 7.8 0.0 2.8 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ETS83593.1 - 0.12 12.9 3.3 5.7 7.6 0.2 3.6 4 0 0 4 4 4 0 HEAT-like repeat PAN_1 PF00024.26 ETS83594.1 - 9.8e-08 31.9 2.8 0.01 15.8 0.1 2.4 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.6 ETS83594.1 - 0.0008 19.3 4.9 0.0054 16.6 0.6 2.4 2 0 0 2 2 2 2 PAN domain Nitrate_red_gam PF02665.14 ETS83594.1 - 0.014 14.9 0.3 0.023 14.2 0.3 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Fungal_trans_2 PF11951.8 ETS83595.1 - 6.8e-35 120.6 6.6 3.8e-34 118.1 6.6 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS83595.1 - 2.5e-07 30.7 9.1 4.3e-07 29.9 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ApbA_C PF08546.11 ETS83596.1 - 9e-29 100.2 0.0 4.6e-28 97.9 0.0 2.1 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 ETS83596.1 - 2.1e-22 79.4 0.0 3.1e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HCV_NS4a PF01006.20 ETS83596.1 - 0.023 14.5 0.1 0.056 13.2 0.1 1.7 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a Aminotran_1_2 PF00155.21 ETS83597.1 - 2.4e-16 59.9 0.0 3.2e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ETS83597.1 - 5.9e-08 31.9 0.0 4e-07 29.2 0.0 2.0 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase MFS_1 PF07690.16 ETS83598.1 - 9.7e-32 110.3 74.9 1.4e-28 99.8 44.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS83598.1 - 0.00085 18.3 43.8 0.0092 14.9 17.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter R3H-assoc PF13902.6 ETS83599.1 - 3.6e-21 76.0 3.9 3.6e-21 76.0 3.9 1.8 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.22 ETS83599.1 - 0.045 13.7 0.7 0.25 11.4 0.0 2.5 3 0 0 3 3 3 0 R3H domain Pyr_redox_3 PF13738.6 ETS83600.1 - 6.1e-15 55.3 0.0 3.1e-12 46.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS83600.1 - 1.7e-12 47.2 0.0 5.9e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ETS83600.1 - 5.7e-09 34.9 0.2 2.7e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ETS83600.1 - 1.6e-07 30.8 0.0 4.2e-05 22.9 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 ETS83600.1 - 0.099 12.0 0.1 0.24 10.8 0.0 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 ETS83600.1 - 0.1 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 ETS83600.1 - 0.12 11.4 0.1 0.24 10.4 0.0 1.4 2 0 0 2 2 2 0 Lycopene cyclase protein ATP19 PF11022.8 ETS83604.1 - 1.5e-28 99.0 0.1 1.7e-28 98.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit K DUF3360 PF11840.8 ETS83604.1 - 0.23 10.2 0.3 0.26 10.0 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) MTP18 PF10558.9 ETS83605.1 - 2.8e-83 278.0 0.0 3.7e-83 277.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) zf-AN1 PF01428.16 ETS83606.1 - 1.6e-24 85.8 23.0 3.5e-12 46.3 8.5 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 ETS83606.1 - 0.029 14.7 13.9 0.54 10.6 4.6 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain IBR PF01485.21 ETS83606.1 - 0.054 13.7 18.5 0.057 13.7 3.4 2.6 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Rad4 PF03835.15 ETS83607.1 - 1.8e-31 108.8 0.2 1.8e-31 108.8 0.2 2.6 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 ETS83607.1 - 1.9e-28 98.7 0.2 3.5e-28 97.8 0.2 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 ETS83607.1 - 7.3e-20 70.6 0.8 2e-19 69.2 0.8 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 ETS83607.1 - 3.4e-14 53.5 1.0 3.4e-14 53.5 1.0 6.3 6 1 0 6 6 6 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 ETS83607.1 - 0.0013 19.1 0.0 0.0078 16.7 0.0 2.4 1 1 0 1 1 1 1 Transglutaminase-like superfamily p450 PF00067.22 ETS83608.1 - 9.8e-18 64.1 0.0 1.5e-16 60.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 PhzC-PhzF PF02567.16 ETS83609.1 - 2.7e-32 112.4 0.6 2.3e-19 69.9 0.0 2.1 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein Ion_trans PF00520.31 ETS83610.1 - 4.6e-06 26.0 24.5 1.2e-05 24.7 24.5 1.7 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 ETS83610.1 - 0.00015 20.6 13.9 0.0082 14.9 5.1 2.2 1 1 1 2 2 2 2 Polycystin cation channel PNTB_4TM PF12769.7 ETS83610.1 - 0.011 16.2 0.3 0.011 16.2 0.3 1.9 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch Ank_2 PF12796.7 ETS83611.1 - 1.4e-59 198.6 0.2 3e-11 43.8 0.0 6.8 6 2 0 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS83611.1 - 1e-40 137.6 0.3 1.3e-05 25.7 0.0 11.2 5 3 8 13 13 13 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS83611.1 - 5.8e-34 115.7 6.3 3.9e-06 27.0 0.1 10.0 5 2 6 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS83611.1 - 2.8e-33 110.2 9.8 0.019 15.5 0.0 14.3 14 0 0 14 14 14 9 Ankyrin repeat Ank PF00023.30 ETS83611.1 - 5.3e-25 86.7 13.4 0.078 13.5 0.0 13.1 13 2 1 14 14 14 7 Ankyrin repeat FCD PF07729.12 ETS83611.1 - 0.0079 16.6 0.0 4.5 7.7 0.0 4.2 3 1 1 4 4 4 1 FCD domain DUF3447 PF11929.8 ETS83611.1 - 0.013 15.4 0.0 3.7 7.6 0.0 4.4 6 1 0 6 6 6 0 Domain of unknown function (DUF3447) Shigella_OspC PF06128.11 ETS83611.1 - 0.059 13.1 0.1 3.3 7.4 0.1 3.1 3 0 0 3 3 3 0 Shigella flexneri OspC protein Cupin_3 PF05899.12 ETS83612.1 - 7.2e-10 38.4 0.0 1.7e-09 37.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF861) EutQ PF06249.12 ETS83612.1 - 9.4e-10 38.4 0.0 1.2e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_2 PF07883.11 ETS83612.1 - 0.00014 21.5 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Pirin PF02678.16 ETS83612.1 - 0.0094 15.9 0.0 0.012 15.5 0.0 1.4 1 1 0 1 1 1 1 Pirin DUF1859 PF08948.10 ETS83612.1 - 0.089 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1859) Cupin_6 PF12852.7 ETS83612.1 - 0.21 11.3 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Cupin DUF3445 PF11927.8 ETS83613.1 - 6.8e-77 258.1 0.0 8.3e-77 257.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Fungal_trans_2 PF11951.8 ETS83614.1 - 7.6e-28 97.4 1.1 3.3e-27 95.3 1.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS83614.1 - 2.6e-07 30.6 9.2 4.7e-07 29.8 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S18 PF01084.20 ETS83614.1 - 0.052 13.8 1.3 0.23 11.7 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S18 Abhydrolase_6 PF12697.7 ETS83615.1 - 4.5e-10 40.5 0.2 5.9e-10 40.1 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ETS83615.1 - 3.8e-09 36.3 0.0 0.0019 17.7 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 ETS83615.1 - 5.3e-08 31.9 0.0 0.00087 18.1 0.0 2.3 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 ETS83615.1 - 2.9e-07 30.0 0.0 7.9e-06 25.3 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS83615.1 - 1e-06 28.6 0.0 8.3e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 ETS83615.1 - 0.00011 22.0 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1100 PF06500.11 ETS83615.1 - 0.00016 20.6 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) BAAT_C PF08840.11 ETS83615.1 - 0.00096 19.1 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 ETS83615.1 - 0.0013 18.4 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family PhoPQ_related PF10142.9 ETS83615.1 - 0.18 10.5 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein ADH_zinc_N PF00107.26 ETS83616.1 - 5.3e-10 39.4 0.0 8.6e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS83616.1 - 1.1e-08 34.9 0.0 2.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ETS83616.1 - 3e-06 28.3 0.0 5.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase p450 PF00067.22 ETS83618.1 - 7.7e-40 137.0 0.0 9.2e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FBA_2 PF07735.17 ETS83618.1 - 0.26 11.4 0.0 0.26 11.4 0.0 2.3 3 0 0 3 3 3 0 F-box associated CinA PF02464.17 ETS83619.1 - 2.8e-34 117.9 0.3 3.2e-34 117.7 0.3 1.0 1 0 0 1 1 1 1 Competence-damaged protein DUF1929 PF09118.11 ETS83620.1 - 2.7e-23 82.1 0.3 5.7e-23 81.0 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) PAN_1 PF00024.26 ETS83620.1 - 9.7e-16 57.5 11.6 7.3e-08 32.3 0.5 2.4 2 0 0 2 2 2 2 PAN domain Kelch_6 PF13964.6 ETS83620.1 - 5.3e-13 48.8 7.8 0.00046 20.4 0.0 5.4 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 ETS83620.1 - 2.9e-10 39.5 5.0 7.7e-05 22.2 0.4 4.6 3 2 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 ETS83620.1 - 2.9e-08 33.4 1.1 0.0031 17.4 0.2 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 ETS83620.1 - 1.4e-07 31.4 12.9 0.089 12.8 0.2 5.7 5 1 0 5 5 5 3 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.11 ETS83620.1 - 4e-07 29.5 0.6 0.063 12.5 0.0 3.4 2 1 1 3 3 3 2 Glyoxal oxidase N-terminus PAN_4 PF14295.6 ETS83620.1 - 8.7e-06 25.5 14.5 0.0011 18.8 1.6 3.1 3 0 0 3 3 3 2 PAN domain MANEC PF07502.14 ETS83620.1 - 0.017 15.4 7.9 1.4 9.3 2.6 2.4 2 0 0 2 2 2 0 MANEC domain DUF1668 PF07893.13 ETS83620.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1668) PAN_3 PF08277.12 ETS83620.1 - 1.5 8.7 11.9 1.7 8.5 4.1 2.6 2 0 0 2 2 2 0 PAN-like domain Fer4_20 PF14691.6 ETS83620.1 - 1.9 8.3 6.1 2.2 8.1 1.1 2.2 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster PAN_2 PF08276.11 ETS83620.1 - 2 8.6 15.6 1.6 8.9 5.1 2.5 2 0 0 2 2 2 0 PAN-like domain E1-E2_ATPase PF00122.20 ETS83621.1 - 2.1e-18 66.5 0.0 4.7e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ETS83621.1 - 2.5e-12 47.6 7.0 1.3e-07 32.2 4.8 3.4 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ETS83621.1 - 0.0029 17.7 0.0 0.0077 16.3 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ETS83621.1 - 0.011 15.5 0.0 0.18 11.5 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4059 PF13268.6 ETS83621.1 - 0.098 13.1 0.5 6.3 7.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) Cation_ATPase_N PF00690.26 ETS83621.1 - 0.13 12.0 0.0 0.38 10.5 0.0 1.8 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus UPF0052 PF01933.18 ETS83622.1 - 1.2e-63 215.1 0.0 1.5e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Sugar_tr PF00083.24 ETS83623.1 - 9e-82 275.3 19.4 1.1e-81 275.1 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS83623.1 - 3.8e-18 65.5 30.4 5.4e-17 61.7 26.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2456 PF10445.9 ETS83623.1 - 0.78 9.9 6.6 9.4 6.4 1.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) Cation_ATPase_C PF00689.21 ETS83624.1 - 1.3e-48 165.1 11.2 1.3e-48 165.1 11.2 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ETS83624.1 - 2.5e-33 115.1 3.3 2.5e-33 115.1 3.3 2.6 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 ETS83624.1 - 9.2e-21 73.7 0.0 1.7e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ETS83624.1 - 2.2e-20 73.9 3.4 7.1e-20 72.2 3.4 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ETS83624.1 - 1.3e-11 44.0 2.9 5.8e-11 41.9 0.0 2.9 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ETS83624.1 - 2e-05 24.5 0.5 0.00094 19.0 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FSH1 PF03959.13 ETS83625.1 - 7.6e-30 104.2 0.0 2.2e-29 102.7 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 ETS83625.1 - 0.0089 15.7 0.0 1.9 8.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Sulfate_transp PF00916.20 ETS83626.1 - 2.4e-82 276.7 12.4 3.2e-82 276.3 12.4 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ETS83626.1 - 3.1e-19 68.7 0.0 6e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ETS83626.1 - 1.9e-05 24.9 0.1 0.00054 20.2 0.0 2.7 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 ETS83626.1 - 0.00065 20.1 10.8 0.002 18.5 3.9 2.7 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily p450 PF00067.22 ETS83627.1 - 3.7e-74 250.1 0.0 4.7e-74 249.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CFEM PF05730.11 ETS83628.1 - 0.00014 21.9 8.0 0.00073 19.6 8.0 2.1 1 1 0 1 1 1 1 CFEM domain FAD_binding_3 PF01494.19 ETS83629.1 - 9.3e-33 113.9 0.1 2.5e-32 112.5 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ETS83629.1 - 1.7e-08 34.1 0.1 1.7e-06 27.5 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS83629.1 - 7.7e-08 32.3 0.4 8.9e-05 22.2 0.1 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS83629.1 - 9.5e-05 22.6 0.4 0.0004 20.6 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ETS83629.1 - 0.00058 19.3 0.2 0.37 10.0 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 ETS83629.1 - 0.001 18.2 1.0 0.0072 15.4 0.5 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 ETS83629.1 - 0.0017 18.9 1.1 0.017 15.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS83629.1 - 0.0055 16.0 0.4 0.031 13.5 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS83629.1 - 0.0064 15.8 0.1 0.021 14.1 0.0 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 ETS83629.1 - 0.011 14.8 0.5 0.025 13.7 0.5 1.6 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 ETS83629.1 - 0.014 15.9 0.0 0.031 14.7 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding HI0933_like PF03486.14 ETS83629.1 - 0.028 13.1 0.4 0.16 10.6 0.4 1.9 1 1 0 1 1 1 0 HI0933-like protein SE PF08491.10 ETS83629.1 - 0.044 12.8 0.0 0.94 8.5 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_9 PF13454.6 ETS83629.1 - 0.085 12.8 1.6 12 5.9 0.0 3.2 3 1 0 3 3 3 0 FAD-NAD(P)-binding GFA PF04828.14 ETS83630.1 - 1.2e-16 60.8 1.8 2.6e-08 34.1 2.1 2.5 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 ETS83630.1 - 3.4 7.9 0.0 3.4 7.9 0.0 3.0 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Gram_pos_anchor PF00746.21 ETS83631.1 - 0.024 14.6 0.1 0.048 13.6 0.1 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif HNF_C PF09354.10 ETS83631.1 - 0.038 15.0 2.4 0.038 15.0 2.4 2.2 2 0 0 2 2 2 0 HNF3 C-terminal domain RIFIN PF02009.16 ETS83631.1 - 0.25 11.2 0.0 0.38 10.6 0.0 1.2 1 0 0 1 1 1 0 Rifin Whi5 PF08528.11 ETS83632.1 - 5.8e-10 38.6 0.0 9.9e-10 37.8 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Rick_17kDa_Anti PF05433.15 ETS83633.1 - 8.4e-06 25.5 15.1 8.4e-06 25.5 15.1 2.9 2 1 0 2 2 2 1 Glycine zipper 2TM domain DUF2076 PF09849.9 ETS83633.1 - 0.0015 18.7 12.0 0.0015 18.7 12.0 3.3 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2076) Gly-zipper_YMGG PF13441.6 ETS83633.1 - 0.0036 17.0 14.2 0.0036 17.0 14.2 3.4 1 1 1 2 2 2 1 YMGG-like Gly-zipper ATPase_gene1 PF09527.10 ETS83633.1 - 0.11 12.7 4.1 0.22 11.7 4.1 1.4 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Gly-zipper_Omp PF13488.6 ETS83633.1 - 5.6 7.1 22.7 0.094 12.7 9.7 2.7 2 0 0 2 2 2 0 Glycine zipper Alpha-amylase PF00128.24 ETS83634.1 - 2.3e-109 366.0 1.1 3.4e-109 365.5 0.0 1.7 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 ETS83634.1 - 6.6e-06 26.2 0.0 1.5e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 ETS83634.1 - 3.1e-05 23.3 0.0 5.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain TMEM154 PF15102.6 ETS83636.1 - 0.00034 20.6 2.1 0.00034 20.6 2.1 2.0 2 1 0 2 2 2 1 TMEM154 protein family TNFR_16_TM PF18422.1 ETS83636.1 - 0.0085 16.0 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 Tumor necrosis factor receptor member 16 trans-membrane domain stn_TNFRSF12A PF12191.8 ETS83636.1 - 0.0095 16.2 0.3 0.022 15.0 0.3 1.7 1 1 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Syndecan PF01034.20 ETS83636.1 - 0.013 15.3 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 ETS83636.1 - 0.058 14.3 0.0 0.15 12.9 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RIFIN PF02009.16 ETS83636.1 - 0.072 13.0 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 Rifin DUF5305 PF17231.2 ETS83636.1 - 0.079 12.3 1.1 0.12 11.7 1.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Gram_pos_anchor PF00746.21 ETS83636.1 - 0.079 12.9 4.0 0.43 10.6 0.7 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Chordopox_A13L PF05961.11 ETS83636.1 - 0.17 12.1 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Peptidase_M56 PF05569.11 ETS83636.1 - 0.28 10.3 0.0 0.39 9.9 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 MFS_1 PF07690.16 ETS83637.1 - 7.7e-13 48.1 8.8 7.7e-13 48.1 8.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 ETS83637.1 - 1.6e-05 24.6 1.4 1.6e-05 24.6 1.4 1.7 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 zf-H2C2_2 PF13465.6 ETS83638.1 - 1.8e-08 34.4 0.6 1.8e-08 34.4 0.6 4.2 5 1 0 5 5 3 2 Zinc-finger double domain NACHT PF05729.12 ETS83638.1 - 4.9e-07 29.8 0.0 1.8e-06 28.0 0.0 2.1 1 0 0 1 1 1 1 NACHT domain zf-met PF12874.7 ETS83638.1 - 7.9e-07 29.3 11.6 0.06 13.7 1.3 3.9 4 0 0 4 4 3 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 ETS83638.1 - 9.3e-07 29.0 37.1 3.2e-05 24.1 2.0 6.0 6 0 0 6 6 5 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ETS83638.1 - 0.00025 21.2 12.7 0.1 12.9 1.2 4.3 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 ETS83638.1 - 0.00038 21.1 26.9 0.0034 18.1 1.7 5.5 5 0 0 5 5 5 2 C2H2-type zinc finger AAA PF00004.29 ETS83638.1 - 0.0059 17.0 0.2 0.032 14.7 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 ETS83638.1 - 0.0091 15.2 0.0 0.021 14.0 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 ETS83638.1 - 0.0093 16.4 0.0 0.081 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS83638.1 - 0.012 15.8 0.0 0.047 14.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain zf-C2H2_2 PF12756.7 ETS83638.1 - 0.02 15.2 2.2 0.02 15.2 2.2 4.1 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf_ZIC PF18366.1 ETS83638.1 - 0.028 14.5 0.7 0.028 14.5 0.7 2.9 2 1 1 3 3 3 0 Zic proteins zinc finger domain DUF2075 PF09848.9 ETS83638.1 - 0.078 12.2 0.0 0.64 9.2 0.0 2.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) zf-C2H2_8 PF15909.5 ETS83638.1 - 0.09 13.1 5.1 0.65 10.3 4.1 2.7 1 1 0 2 2 2 0 C2H2-type zinc ribbon PyrI_C PF02748.15 ETS83638.1 - 0.55 10.2 2.5 30 4.6 0.3 2.7 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn-ribbon_8 PF09723.10 ETS83638.1 - 0.93 9.7 3.5 2.8 8.1 2.6 2.3 1 1 1 2 2 2 0 Zinc ribbon domain SNF2_N PF00176.23 ETS83639.1 - 3.4e-48 164.2 0.0 6.3e-48 163.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS83639.1 - 4.6e-11 43.0 0.0 3.9e-10 40.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ETS83639.1 - 0.0045 16.8 0.0 0.047 13.5 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Rib_5-P_isom_A PF06026.14 ETS83640.1 - 2.2e-45 154.3 0.0 3.2e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Ras PF00071.22 ETS83641.1 - 2.1e-46 157.5 0.3 3.1e-46 156.9 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS83641.1 - 1.1e-25 90.2 0.2 2e-25 89.3 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS83641.1 - 2.6e-12 46.6 0.3 3.2e-12 46.3 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ETS83641.1 - 4.9e-06 26.2 0.1 1.1e-05 25.0 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ETS83641.1 - 0.0084 15.5 0.2 0.011 15.1 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TetR_C_16 PF17920.1 ETS83641.1 - 0.014 15.7 0.0 0.58 10.4 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TIR_2 PF13676.6 ETS83641.1 - 0.018 15.6 0.1 0.03 14.9 0.1 1.4 1 0 0 1 1 1 0 TIR domain FlgH PF02107.16 ETS83641.1 - 0.023 14.3 0.7 0.03 13.9 0.7 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein Nop53 PF07767.11 ETS83642.1 - 4.9e-105 352.2 33.9 6.1e-105 351.9 33.9 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF4407 PF14362.6 ETS83642.1 - 8 5.7 20.5 0.84 8.9 14.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pyr_redox_2 PF07992.14 ETS83643.1 - 6.9e-43 146.9 0.0 1.2e-42 146.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS83643.1 - 4.3e-14 52.8 0.0 4.8e-10 39.8 0.0 3.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 ETS83643.1 - 2.3e-05 23.6 0.2 5.4e-05 22.5 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 ETS83643.1 - 6.4e-05 22.6 0.3 0.00023 20.9 0.3 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 ETS83643.1 - 0.00033 20.0 0.9 0.00067 19.0 0.9 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 ETS83643.1 - 0.018 15.5 0.1 0.048 14.1 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair Cyclase PF04199.13 ETS83644.1 - 5.2e-15 55.9 0.1 7.3e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 Putative cyclase Thiamine_BP PF01910.17 ETS83645.1 - 5.6e-32 109.5 0.2 6.4e-32 109.3 0.2 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Polysacc_deac_1 PF01522.21 ETS83645.1 - 0.0098 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Ykof PF07615.11 ETS83645.1 - 0.03 14.8 0.0 0.041 14.4 0.0 1.3 1 0 0 1 1 1 0 YKOF-related Family CDC37_N PF03234.14 ETS83647.1 - 1.5e-49 168.2 2.1 1.5e-49 168.2 2.1 2.9 3 2 1 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 ETS83647.1 - 5.4e-42 142.4 1.6 3.6e-41 139.8 0.4 2.3 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 ETS83647.1 - 3.5e-31 107.3 6.0 4.6e-31 106.9 3.2 2.5 2 0 0 2 2 2 1 Cdc37 C terminal domain Holin_BhlA PF10960.8 ETS83647.1 - 0.045 13.7 0.3 0.15 12.0 0.3 1.9 1 0 0 1 1 1 0 BhlA holin family DUF1682 PF07946.14 ETS83648.1 - 1.4e-112 376.1 1.6 1.6e-112 375.9 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Big_3 PF07523.12 ETS83648.1 - 0.057 13.7 0.0 9.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) SAD_SRA PF02182.17 ETS83649.1 - 6e-07 29.3 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 SAD/SRA domain Rotamase PF00639.21 ETS83650.1 - 1.5e-08 35.5 0.2 4.2e-08 34.1 0.2 1.9 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 ETS83650.1 - 2.3e-08 34.6 2.9 1.6e-06 28.6 1.3 2.8 1 1 1 2 2 2 1 PPIC-type PPIASE domain adh_short PF00106.25 ETS83651.1 - 2.8e-25 88.9 0.0 2.7e-24 85.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS83651.1 - 7.5e-18 64.9 0.0 3.3e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS83651.1 - 9.7e-08 32.1 0.2 1.2e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 ETS83651.1 - 0.0018 17.7 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 ETS83651.1 - 0.007 16.8 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Epimerase PF01370.21 ETS83651.1 - 0.01 15.3 0.1 0.029 13.8 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 ETS83651.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 ETS83651.1 - 0.021 14.7 0.1 0.036 14.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YAcAr PF10686.9 ETS83651.1 - 0.052 13.5 0.1 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family YjeF_N PF03853.15 ETS83651.1 - 0.059 13.3 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 YjeF-related protein N-terminus ADH_zinc_N PF00107.26 ETS83651.1 - 0.092 12.7 0.0 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase AATase PF07247.12 ETS83652.1 - 2.4e-11 42.9 0.0 3.4e-11 42.4 0.0 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase Ribosomal_L7Ae PF01248.26 ETS83653.1 - 5.1e-28 96.7 0.7 6.3e-28 96.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 ETS83653.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain DUF1846 PF08903.11 ETS83653.1 - 0.17 10.4 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Ribosomal_S8 PF00410.19 ETS83654.1 - 9.9e-22 77.2 0.1 1.5e-21 76.7 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Glyco_transf_90 PF05686.12 ETS83655.1 - 3.4e-16 59.2 6.7 9.2e-14 51.2 6.8 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 RRS1 PF04939.12 ETS83655.1 - 0.034 14.0 0.6 0.098 12.5 0.6 1.8 1 0 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) RNA_pol_Rpc82 PF05645.13 ETS83655.1 - 0.047 13.5 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 Catalase PF00199.19 ETS83656.1 - 8.4e-166 551.8 0.1 1e-165 551.5 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 ETS83656.1 - 2.8e-44 150.4 1.2 4.4e-44 149.8 1.2 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 ETS83656.1 - 2.2e-19 69.4 0.0 4.1e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Haspin_kinase PF12330.8 ETS83657.1 - 7.1e-36 123.9 0.0 1.2e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain MOSC PF03473.17 ETS83659.1 - 2.1e-23 82.8 0.0 7.4e-23 81.0 0.0 2.0 2 0 0 2 2 2 1 MOSC domain Fer2 PF00111.27 ETS83659.1 - 5.7e-12 45.4 1.6 1.5e-11 44.1 1.6 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 ETS83659.1 - 7.6e-09 35.3 0.0 1.4e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 3-alpha domain NAD_binding_6 PF08030.12 ETS83659.1 - 0.013 15.6 0.2 1 9.4 0.0 2.5 2 1 1 3 3 3 0 Ferric reductase NAD binding domain TBCC PF07986.12 ETS83660.1 - 3.6e-31 107.4 0.1 5.7e-31 106.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 ETS83660.1 - 5.7e-08 33.2 0.0 9.7e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Med9 PF07544.13 ETS83661.1 - 3.7e-16 59.0 0.6 6.5e-16 58.2 0.6 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 ETS83661.1 - 8.4e-06 26.1 8.0 1.6e-05 25.2 8.0 1.6 1 1 0 1 1 1 1 Subunit 21 of Mediator complex RskA PF10099.9 ETS83661.1 - 0.0058 17.0 9.4 0.0085 16.4 9.4 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF737 PF05300.11 ETS83661.1 - 0.012 15.9 4.3 0.016 15.6 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) SlyX PF04102.12 ETS83661.1 - 0.016 15.8 1.9 0.016 15.8 1.9 2.4 2 1 0 2 2 1 0 SlyX PsbQ PF05757.11 ETS83661.1 - 0.031 14.0 2.9 0.042 13.6 2.9 1.1 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Fib_alpha PF08702.10 ETS83661.1 - 0.081 13.1 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 ETS83661.1 - 0.096 13.2 0.1 0.13 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF1180 PF06679.12 ETS83661.1 - 0.82 10.1 6.6 1.1 9.7 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) TFIIA PF03153.13 ETS83661.1 - 1.1 9.2 7.0 1.2 9.0 7.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 ETS83661.1 - 1.2 7.7 6.5 1.4 7.6 6.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PKcGMP_CC PF16808.5 ETS83661.1 - 1.3 9.0 5.8 3.6 7.5 5.5 1.8 1 1 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase iPGM_N PF06415.13 ETS83662.1 - 3e-81 272.0 0.0 4.1e-81 271.5 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 ETS83662.1 - 2.8e-65 220.2 0.1 3.5e-65 219.8 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 ETS83662.1 - 0.00015 21.3 0.0 0.00045 19.7 0.0 1.9 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 ETS83662.1 - 0.00053 19.7 0.0 0.00093 18.9 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1877 PF08974.10 ETS83662.1 - 0.05 13.7 0.0 0.72 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1877) AIG2_2 PF13772.6 ETS83662.1 - 0.18 12.2 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 AIG2-like family CSN8_PSD8_EIF3K PF10075.9 ETS83663.1 - 5.2e-43 146.5 0.0 6.9e-43 146.1 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family FA_desaturase PF00487.24 ETS83664.1 - 9.4e-24 84.6 31.7 1.9e-23 83.6 31.7 1.4 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 ETS83664.1 - 0.0079 16.4 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Ank_5 PF13857.6 ETS83665.1 - 3.5e-15 55.8 1.9 2.4e-08 34.1 0.2 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS83665.1 - 4.1e-15 55.9 0.2 3.5e-06 27.4 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS83665.1 - 2.4e-12 47.3 0.5 7.5e-08 32.9 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ETS83665.1 - 9.2e-07 29.0 2.7 0.85 10.2 0.1 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 ETS83665.1 - 1.2e-05 25.3 0.2 0.57 10.9 0.0 4.9 4 0 0 4 4 4 1 Ankyrin repeat CorA PF01544.18 ETS83665.1 - 3.1e-05 23.4 3.3 0.00012 21.5 3.3 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein MYO10_CC PF16735.5 ETS83665.1 - 4.8 7.4 6.0 3.3 7.9 0.2 3.0 3 0 0 3 3 3 0 Unconventional myosin-X coiled coil domain SICA_C PF12879.7 ETS83666.1 - 0.0013 18.8 10.6 0.074 13.1 6.1 2.5 1 1 1 2 2 2 2 SICA C-terminal inner membrane domain TEX19 PF15553.6 ETS83666.1 - 0.96 9.4 10.0 16 5.5 10.0 2.2 1 1 0 1 1 1 0 Testis-expressed protein 19 Cyclase PF04199.13 ETS83667.1 - 2e-13 50.8 0.0 3.3e-13 50.1 0.0 1.4 1 1 0 1 1 1 1 Putative cyclase Lactonase PF10282.9 ETS83668.1 - 2.1e-20 73.3 5.4 2.1e-19 70.0 3.8 2.1 1 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 ETS83668.1 - 0.00069 19.3 0.6 0.0037 16.9 0.3 2.3 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region FMO-like PF00743.19 ETS83670.1 - 6e-17 61.3 0.6 5.3e-13 48.2 0.1 3.1 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ETS83670.1 - 8.8e-11 41.9 0.8 2.6e-10 40.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS83670.1 - 1.5e-10 40.8 0.0 5.8e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS83670.1 - 1.9e-07 30.6 0.0 0.00031 20.0 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ETS83670.1 - 1.1e-06 28.1 0.0 1.3e-05 24.6 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS83670.1 - 0.0001 22.0 0.1 0.28 10.7 0.1 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS83670.1 - 0.00047 20.2 2.0 0.3 11.0 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 ETS83670.1 - 0.0055 16.0 0.2 0.12 11.6 0.0 2.7 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.27 ETS83670.1 - 0.095 13.3 0.9 6.7 7.3 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS83670.1 - 0.58 8.8 1.3 1.5 7.4 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 ETS83670.1 - 1.6 7.8 4.6 3.5 6.6 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A Cyclin PF08613.11 ETS83671.1 - 9.2e-15 55.4 0.1 1.8e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ETS83671.1 - 0.00025 20.8 0.0 0.00047 19.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3947 PF13135.6 ETS83671.1 - 0.21 11.8 6.4 0.56 10.4 6.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) Abhydrolase_3 PF07859.13 ETS83672.1 - 5.9e-58 196.2 0.0 7.7e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS83672.1 - 0.00012 21.2 0.0 0.00054 18.9 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 ETS83672.1 - 0.0033 18.1 1.2 0.0082 16.8 1.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ETS83672.1 - 0.012 15.1 0.0 0.044 13.2 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 ETS83672.1 - 0.054 13.0 0.2 0.14 11.6 0.1 1.6 2 0 0 2 2 2 0 Esterase PHB depolymerase GTP_EFTU PF00009.27 ETS83673.1 - 1.6e-57 194.2 0.0 3e-57 193.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 ETS83673.1 - 9.4e-16 57.6 0.0 2.6e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ETS83673.1 - 6e-10 39.4 0.0 3e-09 37.1 0.0 2.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.6 ETS83673.1 - 6.3e-07 29.4 0.0 1.8e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 ETS83673.1 - 0.0019 18.0 0.0 0.0085 15.9 0.0 2.2 1 1 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 ETS83673.1 - 0.0085 16.2 0.0 0.037 14.1 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase Paf67 PF10255.9 ETS83674.1 - 3.1e-157 523.7 0.2 3.7e-157 523.5 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 ETS83674.1 - 0.039 14.1 0.0 0.2 11.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Usp PF00582.26 ETS83676.1 - 3.5e-16 60.0 1.5 5.2e-15 56.2 0.0 2.5 2 0 0 2 2 2 1 Universal stress protein family Rep_fac-A_C PF08646.10 ETS83676.1 - 0.13 12.0 0.1 16 5.3 0.0 2.3 2 0 0 2 2 2 0 Replication factor-A C terminal domain Peptidase_C15 PF01470.17 ETS83677.1 - 0.0092 16.2 0.0 0.44 10.7 0.0 2.8 2 1 0 2 2 2 1 Pyroglutamyl peptidase GCV_T PF01571.21 ETS83678.1 - 0.09 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain SIN1 PF05422.12 ETS83679.1 - 0.046 14.3 0.9 0.046 14.3 0.9 2.6 2 1 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) DEAD PF00270.29 ETS83680.1 - 1.2e-38 132.7 0.0 2.3e-38 131.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS83680.1 - 1.3e-30 106.0 0.1 4.1e-30 104.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS83680.1 - 9.6e-05 22.5 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ETS83680.1 - 0.0012 19.2 0.1 0.016 15.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain MFMR_assoc PF16596.5 ETS83680.1 - 0.14 12.6 2.6 0.25 11.8 2.6 1.4 1 0 0 1 1 1 0 Disordered region downstream of MFMR Pkinase PF00069.25 ETS83681.1 - 1.8e-63 214.4 0.0 2.2e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS83681.1 - 1.3e-34 119.6 0.0 2e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS83681.1 - 3.3e-06 26.6 0.0 5.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ETS83681.1 - 0.00054 18.9 0.0 0.00076 18.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 ETS83681.1 - 0.23 11.1 0.0 3.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SET PF00856.28 ETS83682.1 - 1.9e-13 51.2 0.0 4.2e-13 50.0 0.0 1.6 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.6 ETS83682.1 - 0.046 14.0 0.2 0.1 12.9 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 ETS83682.1 - 0.33 10.9 0.1 0.33 10.9 0.1 2.7 3 1 0 3 3 3 0 Tetratricopeptide repeat FAD_binding_4 PF01565.23 ETS83683.1 - 1.4e-22 79.9 0.6 2.6e-22 79.0 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain KTI12 PF08433.10 ETS83684.1 - 1.4e-71 241.2 0.0 2.1e-71 240.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 ETS83684.1 - 0.0058 16.8 0.1 0.015 15.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETS83684.1 - 0.0083 16.7 0.2 0.21 12.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 ETS83684.1 - 0.028 14.8 0.0 0.067 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain GT-D PF08759.11 ETS83684.1 - 0.048 13.3 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold AAA_22 PF13401.6 ETS83684.1 - 0.077 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain ThiS-like PF14453.6 ETS83684.1 - 0.17 12.0 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 ThiS-like ubiquitin DUF3397 PF11877.8 ETS83686.1 - 0.095 12.9 0.8 0.095 12.9 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3397) RTA1 PF04479.13 ETS83686.1 - 0.098 12.2 6.0 0.044 13.4 4.0 1.5 1 1 0 1 1 1 0 RTA1 like protein COX8 PF02285.15 ETS83686.1 - 0.15 12.0 0.9 2.2 8.3 0.1 2.8 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII MAPEG PF01124.18 ETS83686.1 - 0.64 9.9 7.5 7 6.6 1.1 2.6 2 1 0 2 2 2 0 MAPEG family SUR7 PF06687.12 ETS83686.1 - 3.3 7.3 7.8 0.44 10.1 2.3 2.3 1 1 1 2 2 2 0 SUR7/PalI family Esterase_phd PF10503.9 ETS83687.1 - 2.3e-06 27.3 0.0 3.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase DUF5042 PF16445.5 ETS83687.1 - 0.054 11.9 0.0 0.081 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5042) Peptidase_S9 PF00326.21 ETS83687.1 - 0.071 12.6 0.0 0.2 11.1 0.0 1.6 1 1 1 2 2 2 0 Prolyl oligopeptidase family Pro_isomerase PF00160.21 ETS83688.1 - 2.1e-50 171.1 0.0 5e-50 169.8 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 ETS83688.1 - 0.00089 19.3 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 ETS83688.1 - 0.0011 19.1 0.0 0.0038 17.4 0.0 1.9 1 0 0 1 1 1 1 U-box domain Lung_7-TM_R PF06814.13 ETS83689.1 - 7e-67 225.7 17.2 8.4e-67 225.5 17.2 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor SurA_N_3 PF13624.6 ETS83689.1 - 8 6.2 5.7 3.8 7.3 0.3 2.7 3 0 0 3 3 3 0 SurA N-terminal domain Condensation PF00668.20 ETS83690.1 - 7.4e-25 87.5 0.0 9.8e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 Condensation domain Transferase PF02458.15 ETS83690.1 - 0.00023 20.0 0.3 0.00064 18.5 0.1 1.7 1 1 0 2 2 2 1 Transferase family UreD PF01774.17 ETS83690.1 - 0.093 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 UreD urease accessory protein FAD_binding_3 PF01494.19 ETS83691.1 - 1.9e-19 70.1 0.1 2.7e-18 66.3 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 ETS83691.1 - 8.5e-05 22.0 0.1 0.00014 21.3 0.1 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 ETS83691.1 - 0.0001 21.7 0.1 0.04 13.2 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ETS83691.1 - 0.00017 20.5 0.7 0.29 10.0 0.0 2.8 2 1 1 3 3 3 2 Tryptophan halogenase Lycopene_cycl PF05834.12 ETS83691.1 - 0.00023 20.3 0.4 0.0078 15.3 0.2 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 ETS83691.1 - 0.00058 20.4 0.2 0.51 10.9 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ETS83691.1 - 0.0038 16.6 1.3 0.007 15.8 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 ETS83691.1 - 0.084 11.9 0.0 0.3 10.1 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase PhoLip_ATPase_C PF16212.5 ETS83692.1 - 5.6e-80 268.7 18.0 5.6e-80 268.7 18.0 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ETS83692.1 - 6e-27 93.1 7.2 1.7e-26 91.7 7.2 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 ETS83692.1 - 4.1e-12 46.8 1.1 2.1e-07 31.4 0.3 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ETS83692.1 - 4.9e-12 45.8 0.1 6.5e-11 42.2 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 ETS83692.1 - 1.8e-07 30.9 1.5 2e-07 30.7 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ETS83692.1 - 0.00024 21.0 0.8 0.00069 19.4 0.8 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Abhydrolase_1 PF00561.20 ETS83693.1 - 7.1e-22 78.3 0.0 2.2e-16 60.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS83693.1 - 5.4e-14 53.3 0.0 8.4e-14 52.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS83693.1 - 2.8e-08 33.3 0.0 1.3e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 EHN PF06441.12 ETS83693.1 - 0.011 16.1 0.0 0.035 14.5 0.0 1.8 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Abhydrolase_4 PF08386.10 ETS83693.1 - 0.02 15.0 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Methyltransf_23 PF13489.6 ETS83694.1 - 7.2e-19 68.2 0.0 1.2e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS83694.1 - 8.4e-08 32.8 0.0 3.7e-07 30.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS83694.1 - 1.2e-06 29.2 0.0 7.6e-06 26.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS83694.1 - 4.9e-06 26.4 0.0 0.00012 21.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS83694.1 - 8.3e-05 23.2 0.0 0.00026 21.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS83694.1 - 0.023 14.0 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Tom22 PF04281.13 ETS83696.1 - 6.1 6.6 9.2 8.2 6.2 9.2 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Pex26 PF07163.12 ETS83697.1 - 5.1e-05 22.7 4.5 5.9e-05 22.5 1.8 2.1 2 0 0 2 2 2 1 Pex26 protein Ribonuc_L-PSP PF01042.21 ETS83697.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Endoribonuclease L-PSP DUF5401 PF17380.2 ETS83697.1 - 3 5.8 20.9 4.3 5.3 20.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF1451 PF07295.11 ETS83697.1 - 3.3 7.7 9.0 6.2 6.9 9.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain PHF5 PF03660.14 ETS83698.1 - 1.6e-46 156.8 11.7 1.8e-46 156.6 11.7 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 ETS83698.1 - 0.39 8.5 7.0 0.4 8.5 7.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 ETS83698.1 - 2.4 8.3 16.0 5.7 7.1 2.2 3.0 1 1 1 2 2 2 0 Double zinc ribbon Pinin_SDK_memA PF04696.13 ETS83699.1 - 3.1e-31 108.1 14.3 3.1e-31 108.1 14.3 2.1 3 0 0 3 3 3 1 pinin/SDK/memA/ protein conserved region RSB_motif PF16294.5 ETS83699.1 - 5.8 7.2 25.4 0.14 12.4 11.5 3.3 2 1 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif MFS_1 PF07690.16 ETS83700.1 - 1.2e-16 60.6 26.1 1.2e-16 60.6 26.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS83700.1 - 0.00011 20.8 7.7 0.00021 19.9 7.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pyr_redox_2 PF07992.14 ETS83701.1 - 4.2e-53 180.5 0.2 5.3e-53 180.2 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS83701.1 - 3e-11 43.7 0.4 1.1e-09 38.7 0.1 3.2 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS83701.1 - 0.0016 17.7 1.7 0.38 9.9 0.1 2.9 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase TPPII_N PF12583.8 ETS83701.1 - 0.024 15.2 1.5 1.4 9.5 0.0 2.4 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal EcoR124_C PF12008.8 ETS83701.1 - 0.044 13.4 0.4 0.081 12.6 0.0 1.5 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal DUF501 PF04417.12 ETS83701.1 - 0.15 11.9 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF501) RPE65 PF03055.15 ETS83702.1 - 3.6e-86 290.2 0.0 4.1e-86 290.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Fungal_trans PF04082.18 ETS83703.1 - 1.4e-29 103.0 0.2 2.1e-29 102.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GMC_oxred_N PF00732.19 ETS83704.1 - 6e-41 140.7 0.0 3.1e-40 138.4 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS83704.1 - 2.5e-24 86.5 0.0 4.6e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 ETS83704.1 - 0.00021 20.6 0.2 0.00039 19.7 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 ETS83704.1 - 0.00024 20.3 0.1 0.00039 19.6 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ETS83704.1 - 0.0012 19.1 0.0 0.0036 17.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS83704.1 - 0.0035 17.0 0.3 0.0075 15.9 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS83704.1 - 0.0041 16.2 0.4 0.0084 15.2 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 ETS83704.1 - 0.0081 15.4 2.7 0.24 10.6 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS83704.1 - 0.036 13.3 0.1 0.17 11.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS83704.1 - 0.044 12.5 0.2 0.067 11.9 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 ETS83704.1 - 0.064 12.5 0.1 0.097 11.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Use1 PF09753.9 ETS83705.1 - 7.3e-12 45.5 0.1 7.3e-12 45.5 0.1 2.0 1 1 0 2 2 2 1 Membrane fusion protein Use1 TBCC_N PF16752.5 ETS83705.1 - 8.2 6.9 16.8 0.62 10.5 4.1 2.7 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain BRCT_2 PF16589.5 ETS83706.1 - 8.3e-06 26.1 0.0 2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ETS83706.1 - 0.0014 18.9 0.0 0.0032 17.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 ETS83706.1 - 0.0078 16.5 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain DUF1501 PF07394.12 ETS83707.1 - 0.014 14.5 3.1 0.022 13.8 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF2461 PF09365.10 ETS83707.1 - 0.16 11.9 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) SprA-related PF12118.8 ETS83707.1 - 0.74 8.9 6.6 1.1 8.3 6.6 1.3 1 0 0 1 1 1 0 SprA-related family Rrp15p PF07890.12 ETS83707.1 - 1.2 9.4 11.4 2.2 8.6 11.4 1.3 1 0 0 1 1 1 0 Rrp15p RR_TM4-6 PF06459.12 ETS83707.1 - 2.8 7.7 9.0 4.6 7.0 9.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.10 ETS83707.1 - 2.9 6.5 8.2 4.1 6.0 8.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Syndecan PF01034.20 ETS83708.1 - 0.17 11.9 0.1 0.37 10.7 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain Thioredoxin PF00085.20 ETS83710.1 - 6.9e-25 87.0 0.1 8.5e-25 86.7 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 ETS83710.1 - 1e-07 31.6 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 ETS83710.1 - 5e-07 30.0 0.0 2e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 ETS83710.1 - 1.3e-06 28.8 0.4 4.3e-06 27.1 0.4 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 ETS83710.1 - 8.1e-05 22.4 0.0 9.8e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 ETS83710.1 - 0.00054 19.7 0.3 0.17 11.6 0.1 2.1 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.21 ETS83710.1 - 0.00067 19.6 0.3 0.066 13.1 0.1 2.1 1 1 1 2 2 2 1 AhpC/TSA family TraF PF13728.6 ETS83710.1 - 0.0015 18.4 0.1 0.0023 17.8 0.1 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein HyaE PF07449.11 ETS83710.1 - 0.012 15.6 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 ETS83710.1 - 0.027 14.2 0.6 0.083 12.6 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.6 ETS83710.1 - 0.03 14.4 0.0 0.05 13.6 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin domain Rogdi_lz PF10259.9 ETS83710.1 - 0.068 12.6 0.0 0.082 12.4 0.0 1.1 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein DIM1 PF02966.16 ETS83710.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 His_Phos_2 PF00328.22 ETS83711.1 - 1.2e-69 235.5 0.0 1.4e-69 235.3 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ribosomal_S19e PF01090.19 ETS83712.1 - 7.9e-60 200.5 0.1 9e-60 200.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Zip PF02535.22 ETS83713.1 - 1.3e-61 208.7 10.9 1.5e-61 208.4 10.9 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter MDM10 PF12519.8 ETS83714.1 - 1.4e-168 561.6 0.0 1.6e-168 561.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 ETS83714.1 - 0.0032 17.0 0.0 1.5 8.2 0.1 2.4 2 0 0 2 2 2 2 Eukaryotic porin F-box-like PF12937.7 ETS83715.1 - 2e-06 27.6 0.4 6.3e-06 26.0 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ETS83715.1 - 0.02 14.7 1.9 0.31 11.0 1.9 2.4 1 1 0 1 1 1 0 F-box domain Acetyltransf_10 PF13673.7 ETS83716.1 - 1.7e-10 40.9 0.0 3.6e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS83716.1 - 5.9e-10 39.4 0.0 1.1e-08 35.3 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS83716.1 - 3.1e-09 37.1 0.0 5.6e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETS83716.1 - 0.0032 17.6 0.1 0.01 15.9 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS83716.1 - 0.023 14.6 0.0 0.054 13.5 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein DUF3565 PF12088.8 ETS83716.1 - 0.14 12.1 2.6 11 6.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3565) Glyco_hydro_72 PF03198.14 ETS83718.1 - 3.4e-113 378.1 0.5 4.2e-113 377.8 0.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 ETS83718.1 - 0.00011 21.7 0.1 0.35 10.2 0.0 2.3 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) MRP-L46 PF11788.8 ETS83719.1 - 6.7e-28 97.8 0.0 1.7e-27 96.5 0.0 1.7 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 ETS83719.1 - 0.008 16.2 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain ABA_GPCR PF12430.8 ETS83720.1 - 4.1e-59 199.4 0.3 4.1e-59 199.4 0.3 1.7 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 ETS83720.1 - 2.1e-25 88.6 4.9 5.1e-25 87.4 0.0 3.2 4 0 0 4 4 4 1 The Golgi pH Regulator (GPHR) Family N-terminal YflT PF11181.8 ETS83720.1 - 0.018 15.5 0.1 0.034 14.6 0.1 1.3 1 0 0 1 1 1 0 Heat induced stress protein YflT Ank_2 PF12796.7 ETS83721.1 - 8.7e-34 116.0 0.2 1.9e-11 44.3 0.0 6.9 4 3 4 8 8 8 4 Ankyrin repeats (3 copies) HET PF06985.11 ETS83721.1 - 8e-33 113.8 1.2 1.5e-32 113.0 1.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_4 PF13637.6 ETS83721.1 - 7.7e-26 90.1 6.6 0.00012 22.5 0.0 9.2 8 1 1 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS83721.1 - 1.7e-25 86.3 5.3 0.0013 19.1 0.0 10.2 10 1 1 11 11 11 6 Ankyrin repeat Ank_5 PF13857.6 ETS83721.1 - 1.6e-22 79.3 6.0 8.4e-08 32.3 0.0 7.2 4 2 4 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 ETS83721.1 - 3.3e-22 77.9 5.0 0.00025 21.3 0.0 9.0 9 0 0 9 9 9 4 Ankyrin repeat His_Phos_1 PF00300.22 ETS83721.1 - 0.061 13.0 0.2 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Bac_rhamnosid6H PF17389.2 ETS83722.1 - 3.3e-18 66.0 0.5 2.2e-17 63.3 0.1 2.2 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 ETS83722.1 - 2.1e-10 40.2 0.1 4.6e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF608 PF04685.13 ETS83722.1 - 8.3e-06 25.2 1.0 8.3e-06 25.2 1.0 1.5 2 0 0 2 2 2 1 Glycosyl-hydrolase family 116, catalytic region GDE_C PF06202.14 ETS83722.1 - 9.9e-06 24.7 0.1 3.2e-05 23.0 0.1 1.7 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Bac_rhamnosid PF05592.11 ETS83722.1 - 0.00069 19.6 0.0 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Glyco_hydro_36 PF17167.4 ETS83722.1 - 0.095 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain ELFV_dehydrog PF00208.21 ETS83723.1 - 3.7e-63 213.5 0.0 5.5e-63 212.9 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 ETS83723.1 - 3.7e-20 71.2 0.1 3.3e-15 54.8 0.0 2.3 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 ETS83723.1 - 0.00046 20.1 0.0 0.0059 16.5 0.0 2.3 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Aminotran_5 PF00266.19 ETS83724.1 - 1.5e-11 43.9 0.0 1.4e-09 37.4 0.1 2.0 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ETS83724.1 - 2.6e-06 26.2 0.0 3.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ETS83724.1 - 0.00079 18.8 0.3 0.0014 18.0 0.3 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 ETS83724.1 - 0.02 14.0 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II OKR_DC_1 PF01276.20 ETS83724.1 - 0.096 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain NACHT PF05729.12 ETS83725.1 - 5.4e-07 29.7 0.0 1.4e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 ETS83725.1 - 6.4e-07 30.0 0.0 2.1e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ETS83725.1 - 2.4e-06 27.9 0.1 1.6e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS83725.1 - 0.00013 22.4 0.8 0.0022 18.4 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain ATPase PF06745.13 ETS83725.1 - 0.0021 17.4 0.0 0.0066 15.8 0.0 1.8 2 0 0 2 2 2 1 KaiC DUF2075 PF09848.9 ETS83725.1 - 0.0026 17.1 0.1 0.0077 15.5 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Ank_2 PF12796.7 ETS83725.1 - 0.0027 18.3 0.0 1.6 9.4 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) IstB_IS21 PF01695.17 ETS83725.1 - 0.0048 16.7 0.0 0.073 12.8 0.0 2.5 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_25 PF13481.6 ETS83725.1 - 0.022 14.4 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ETS83725.1 - 0.022 15.1 0.0 0.061 13.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 ETS83725.1 - 0.034 13.9 0.0 0.097 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ETS83725.1 - 0.034 14.2 0.0 0.095 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ETS83725.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 ETS83725.1 - 0.048 14.1 0.0 0.14 12.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4312 PF14189.6 ETS83725.1 - 0.073 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4312) Parvo_NS1 PF01057.17 ETS83725.1 - 0.08 12.0 0.0 0.26 10.3 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 F-box PF00646.33 ETS83726.1 - 0.00094 19.0 0.7 0.0033 17.3 0.3 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ETS83726.1 - 0.12 12.3 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 F-box-like SGL PF08450.12 ETS83727.1 - 3.1e-05 23.7 0.1 6.4e-05 22.6 0.1 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Orthopox_A5L PF06193.11 ETS83728.1 - 0.32 10.4 8.1 0.6 9.5 8.1 1.4 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like TFB6 PF17110.5 ETS83729.1 - 1.1 8.9 5.3 0.25 11.1 0.4 1.9 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH RPN2_C PF18004.1 ETS83729.1 - 7.9 6.4 11.9 6.5 6.6 0.8 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain GST_N PF02798.20 ETS83730.1 - 1e-13 51.4 0.1 4.3e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ETS83730.1 - 5.9e-13 49.0 0.0 9.3e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ETS83730.1 - 1e-10 41.6 0.3 1.8e-10 40.9 0.3 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ETS83730.1 - 1.3e-09 38.1 0.2 2.4e-09 37.3 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ETS83730.1 - 1e-08 35.4 0.0 2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS83730.1 - 2.1e-06 27.7 0.0 3.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 ETS83730.1 - 0.027 14.8 0.1 0.07 13.4 0.0 1.7 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein DUF2034 PF10356.9 ETS83731.1 - 2e-28 99.1 0.0 5.3e-14 52.1 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 ETS83731.1 - 6.6e-08 32.6 0.0 1.2e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.8 ETS83732.1 - 2.1e-45 154.5 8.6 2.4e-45 154.3 8.6 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex KELK PF15796.5 ETS83732.1 - 0.019 15.4 2.7 0.026 15.0 1.2 1.9 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Med9 PF07544.13 ETS83732.1 - 0.021 14.9 2.5 0.021 14.9 2.5 2.2 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 GAS PF13851.6 ETS83732.1 - 0.031 13.6 7.6 0.34 10.2 0.1 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CMV_1a PF12467.8 ETS83732.1 - 0.082 13.3 0.4 0.16 12.3 0.3 1.7 1 1 0 1 1 1 0 Cucumber mosaic virus 1a protein family Fib_alpha PF08702.10 ETS83732.1 - 0.5 10.6 5.4 1.4 9.1 4.6 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family HAD_2 PF13419.6 ETS83733.1 - 1.7e-12 47.8 0.0 2.5e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETS83733.1 - 4.6e-11 43.4 0.0 2.1e-10 41.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ETS83733.1 - 2.5e-05 24.2 0.0 4.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 ETS83733.1 - 0.0036 17.2 0.0 0.049 13.5 0.0 2.0 2 0 0 2 2 2 1 Acid Phosphatase 5_nucleotid PF05761.14 ETS83733.1 - 0.03 13.2 0.0 0.12 11.2 0.0 1.8 1 1 1 2 2 2 0 5' nucleotidase family HAD PF12710.7 ETS83733.1 - 0.092 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pox_F17 PF04767.12 ETS83734.1 - 9.5 6.8 6.6 8 7.0 2.6 2.8 2 0 0 2 2 2 0 DNA-binding 11 kDa phosphoprotein KH_1 PF00013.29 ETS83735.1 - 4.5e-35 119.3 1.5 1.6e-09 37.4 0.0 7.6 8 0 0 8 8 8 6 KH domain HMA PF00403.26 ETS83735.1 - 0.12 12.8 0.6 0.47 10.9 0.0 2.3 2 0 0 2 2 2 0 Heavy-metal-associated domain Acetyltransf_10 PF13673.7 ETS83736.1 - 7.1e-11 42.1 0.0 1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS83736.1 - 4.4e-10 39.8 0.0 8.8e-10 38.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS83736.1 - 9.2e-08 32.4 0.0 1.4e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETS83736.1 - 0.00049 20.2 0.0 1 9.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ETS83736.1 - 0.034 14.3 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pribosyltran PF00156.27 ETS83737.1 - 3.5e-14 52.6 0.1 4.6e-14 52.2 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NOG1_N PF17835.1 ETS83738.1 - 8.5e-51 172.1 0.1 8.5e-51 172.1 0.1 2.1 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 ETS83738.1 - 2.1e-27 94.8 2.8 4.5e-27 93.8 2.8 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 ETS83738.1 - 1.8e-24 85.3 0.1 4.3e-24 84.0 0.1 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 ETS83738.1 - 6.2e-16 58.5 0.0 1.5e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ETS83738.1 - 5.9e-09 35.6 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ETS83738.1 - 0.00097 19.1 0.4 0.2 11.5 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase Gtr1_RagA PF04670.12 ETS83738.1 - 0.0068 15.8 0.1 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 ETS83738.1 - 0.1 12.6 1.0 9.7 6.2 0.0 3.1 2 1 0 3 3 3 0 Dynamin family IF-2B PF01008.17 ETS83739.1 - 2.4e-37 128.7 0.0 3.5e-37 128.1 0.0 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 ETS83739.1 - 0.0054 16.7 0.1 0.8 9.6 0.0 2.3 2 0 0 2 2 2 2 DeoR C terminal sensor domain Methyltransf_33 PF10017.9 ETS83740.1 - 1.5e-89 300.2 0.0 2.2e-89 299.7 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 ETS83740.1 - 3.5e-14 53.0 4.4 3.7e-12 46.4 4.4 2.9 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 ETS83740.1 - 5.5e-05 23.7 0.2 0.00019 21.9 0.2 1.9 1 0 0 1 1 1 1 DinB superfamily MetW PF07021.12 ETS83740.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Peptidase_S28 PF05577.12 ETS83741.1 - 1.3e-47 162.6 0.5 2.7e-47 161.6 0.5 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 DUF3486 PF11985.8 ETS83742.1 - 0.12 12.8 1.0 0.21 12.0 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) Pyr_redox_2 PF07992.14 ETS83743.1 - 1.4e-07 31.1 0.0 3.7e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS83743.1 - 0.0054 16.9 0.0 0.017 15.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain PFK PF00365.20 ETS83743.1 - 0.046 13.1 0.0 0.62 9.3 0.0 2.0 2 0 0 2 2 2 0 Phosphofructokinase Pyr_redox_3 PF13738.6 ETS83743.1 - 0.053 12.8 0.1 0.59 9.3 0.0 2.4 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS83743.1 - 0.12 12.4 0.1 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding ETF PF01012.21 ETS83744.1 - 9.7e-43 146.2 4.2 1.6e-42 145.4 4.2 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 ETS83744.1 - 1.3e-33 114.9 2.4 1.8e-33 114.4 0.5 2.2 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain SWIRM PF04433.17 ETS83745.1 - 6.9e-31 106.4 0.3 1.7e-30 105.2 0.3 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 ETS83745.1 - 8.1e-31 105.8 5.3 1.9e-30 104.7 5.3 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 ETS83745.1 - 3.6e-11 43.1 0.1 7.4e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ETS83745.1 - 2.1e-06 27.9 0.3 4.3e-06 26.9 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Calpain_III PF01067.22 ETS83745.1 - 0.04 14.2 1.8 0.46 10.7 0.0 2.9 4 0 0 4 4 4 0 Calpain large subunit, domain III ABA_WDS PF02496.16 ETS83745.1 - 0.074 13.5 1.2 3.2 8.3 0.4 2.4 2 0 0 2 2 2 0 ABA/WDS induced protein SANT_DAMP1_like PF16282.5 ETS83745.1 - 0.12 12.5 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 DUF3439 PF11921.8 ETS83745.1 - 0.18 11.8 1.8 0.4 10.7 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 ETS83745.1 - 0.58 10.2 12.9 0.094 12.7 1.9 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein ResIII PF04851.15 ETS83747.1 - 4.6e-27 95.1 0.1 9.6e-27 94.1 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ETS83747.1 - 5.6e-16 58.9 0.1 5.3e-14 52.5 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ETS83747.1 - 9e-12 45.1 0.0 6.5e-11 42.3 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 ETS83747.1 - 1.7e-06 27.9 0.1 3.2e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 ETS83747.1 - 0.00064 19.1 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ERCC3_RAD25_C PF16203.5 ETS83747.1 - 0.0035 16.6 0.0 0.0063 15.7 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase C1_1 PF00130.22 ETS83748.1 - 9.6e-05 22.2 2.9 9.6e-05 22.2 2.9 2.3 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 ETS83748.1 - 0.00027 20.4 1.9 0.00056 19.4 1.9 1.6 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 ETS83748.1 - 0.008 16.1 6.2 0.022 14.6 6.2 1.8 1 0 0 1 1 1 1 PHD-finger FYVE_2 PF02318.16 ETS83748.1 - 0.042 14.1 1.1 0.042 14.1 1.1 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger SAP PF02037.27 ETS83748.1 - 0.075 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 SAP domain TGT PF01702.18 ETS83749.1 - 1.2e-130 435.8 0.0 1.3e-130 435.6 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase RecA_dep_nuc PF16786.5 ETS83749.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Recombination enhancement, RecA-dependent nuclease GDI PF00996.18 ETS83751.1 - 1.1e-191 637.1 0.0 1.2e-191 636.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 ETS83751.1 - 0.026 14.8 0.0 0.086 13.1 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MRP-L47 PF06984.13 ETS83752.1 - 1e-23 83.2 2.6 1.5e-23 82.7 2.6 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Fungal_trans PF04082.18 ETS83754.1 - 3.2e-16 59.2 0.3 6.3e-15 54.9 0.3 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 ETS83754.1 - 1.8e-05 24.9 1.1 1.8e-05 24.9 1.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 ETS83754.1 - 0.00071 19.8 4.4 0.0016 18.7 4.4 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 ETS83754.1 - 0.11 13.3 21.6 0.063 14.1 5.8 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ETS83754.1 - 0.16 12.3 3.1 8.8 6.8 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 ETS83754.1 - 0.29 11.7 14.6 0.37 11.3 7.3 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3106 PF11304.8 ETS83756.1 - 0.025 15.0 0.4 0.34 11.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Ysc84 PF04366.12 ETS83758.1 - 8e-32 109.7 0.0 1.4e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Actin PF00022.19 ETS83759.1 - 3.8e-15 55.4 0.0 8.7e-14 50.9 0.0 2.3 2 0 0 2 2 2 2 Actin FtsA PF14450.6 ETS83759.1 - 0.016 15.6 0.0 0.033 14.6 0.0 1.6 1 1 0 1 1 1 0 Cell division protein FtsA Fungal_trans PF04082.18 ETS83760.1 - 7.8e-18 64.4 0.0 1.2e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS83760.1 - 3.5e-07 30.2 8.1 7e-07 29.3 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Senescence PF06911.12 ETS83761.1 - 1.3e-54 185.3 4.4 2.1e-54 184.6 4.4 1.3 1 0 0 1 1 1 1 Senescence-associated protein GCP_N_terminal PF17681.1 ETS83762.1 - 6.7e-24 85.1 0.0 1.1e-23 84.3 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ETS83762.1 - 5.2e-23 82.0 3.4 2.1e-22 80.0 3.4 1.9 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal PA-IL PF07828.12 ETS83762.1 - 0.03 14.3 0.0 0.65 10.0 0.0 2.3 2 0 0 2 2 2 0 PA-IL-like protein SH3_1 PF00018.28 ETS83764.1 - 1.1e-09 37.7 0.1 2.5e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ETS83764.1 - 4.1e-09 36.0 0.1 7.2e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ETS83764.1 - 1.8e-07 30.9 0.2 3.4e-07 30.0 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain RPAP2_Rtr1 PF04181.13 ETS83765.1 - 6.4e-21 74.5 0.0 1.2e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family Ribosomal_S17e PF00833.18 ETS83766.1 - 2.4e-58 195.4 0.2 3.1e-58 195.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal S17 Mit_ribos_Mrp51 PF11709.8 ETS83767.1 - 1.3e-124 416.5 0.2 1.6e-124 416.2 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit DUF3987 PF13148.6 ETS83767.1 - 0.056 12.5 0.4 0.088 11.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) MutL_C PF08676.11 ETS83768.1 - 2.8e-23 82.3 1.9 4.2e-23 81.8 0.1 2.2 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 ETS83768.1 - 5e-19 68.1 0.0 3.6e-18 65.4 0.0 2.3 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 ETS83768.1 - 4e-11 42.9 0.0 1.4e-10 41.1 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ETS83768.1 - 3.8e-07 30.6 0.0 1.3e-06 28.8 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PGAP1 PF07819.13 ETS83769.1 - 2.2e-92 308.9 0.0 3.2e-92 308.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 ETS83769.1 - 1.6e-05 25.6 0.1 4.7e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS83769.1 - 0.0028 17.4 0.0 0.0069 16.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS83769.1 - 0.004 16.4 0.0 0.0076 15.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 ETS83769.1 - 0.024 14.5 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 ETS83769.1 - 0.032 13.7 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 ETS83769.1 - 0.087 12.7 0.0 0.97 9.3 0.0 2.4 3 0 0 3 3 3 0 Lipase (class 3) LCAT PF02450.15 ETS83769.1 - 0.1 11.8 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase VPR PF00522.18 ETS83769.1 - 0.17 11.9 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 VPR/VPX protein Ribosomal_S13_N PF08069.12 ETS83770.1 - 0.046 13.8 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain MtrB_PioB PF11854.8 ETS83770.1 - 0.13 10.6 0.2 0.16 10.3 0.2 1.0 1 0 0 1 1 1 0 Putative outer membrane beta-barrel porin, MtrB/PioB Serinc PF03348.15 ETS83771.1 - 1.9e-163 544.4 8.4 2.1e-163 544.2 8.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF809 PF05663.11 ETS83771.1 - 5.1 7.2 4.8 1.1 9.4 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF809) MFS_1 PF07690.16 ETS83772.1 - 9.3e-18 64.3 31.3 1.7e-15 56.8 7.5 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.13 ETS83772.1 - 2.8e-10 40.1 1.3 2.8e-10 40.1 1.3 2.0 2 0 0 2 2 2 1 Nodulin-like BH3 PF15285.6 ETS83774.1 - 0.008 15.9 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Beclin-1 BH3 domain, Bcl-2-interacting Tyrosinase PF00264.20 ETS83775.1 - 1.6e-49 169.2 1.0 2.1e-49 168.8 1.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF2306 PF10067.9 ETS83776.1 - 1.3e-17 64.4 10.2 2.3e-17 63.6 10.2 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) YqeY PF09424.10 ETS83777.1 - 5e-25 88.3 2.4 6.2e-25 88.0 2.4 1.1 1 0 0 1 1 1 1 Yqey-like protein PI3_PI4_kinase PF00454.27 ETS83779.1 - 2.3e-45 155.4 0.0 3.6e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TIP_N PF12457.8 ETS83779.1 - 0.73 10.2 6.5 0.71 10.3 0.2 3.2 3 0 0 3 3 3 0 Tuftelin interacting protein N terminal Flavodoxin_1 PF00258.25 ETS83780.1 - 1.2e-27 96.9 0.0 2.4e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 ETS83780.1 - 1.7e-25 89.9 0.0 2.5e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 ETS83780.1 - 1.4e-14 54.6 0.0 3e-13 50.4 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Fimbrial_PilY2 PF14481.6 ETS83781.1 - 0.46 10.2 7.1 0.68 9.6 0.8 3.3 3 0 0 3 3 3 0 Type 4 fimbrial biogenesis protein PilY2 Asp PF00026.23 ETS83782.1 - 1.1e-13 51.3 4.2 2.7e-13 50.0 4.2 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease EphA2_TM PF14575.6 ETS83782.1 - 0.0087 16.9 0.2 0.017 16.0 0.2 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 ETS83782.1 - 0.052 13.7 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Podoplanin Syndecan PF01034.20 ETS83782.1 - 0.071 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain CYYR1 PF10873.8 ETS83782.1 - 0.15 12.5 0.1 0.15 12.5 0.1 2.1 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 TMEM154 PF15102.6 ETS83782.1 - 0.17 11.8 0.0 0.57 10.1 0.0 1.9 1 0 0 1 1 1 0 TMEM154 protein family F-box-like PF12937.7 ETS83783.1 - 2.5e-07 30.5 0.0 5.1e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS83783.1 - 3.3e-07 30.0 0.1 4.4e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 F-box domain UIM PF02809.20 ETS83783.1 - 0.22 11.5 16.4 0.25 11.3 2.4 3.7 3 0 0 3 3 3 0 Ubiquitin interaction motif MFS_1 PF07690.16 ETS83784.1 - 7.3e-32 110.7 33.6 1.2e-28 100.1 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS83784.1 - 7.4e-05 21.8 3.9 0.00095 18.1 1.8 2.5 2 0 0 2 2 2 2 MFS_1 like family FKBP_C PF00254.28 ETS83786.1 - 2.9e-26 91.6 0.0 3.6e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ABC_tran PF00005.27 ETS83787.1 - 2.7e-50 170.4 0.1 4.4e-28 98.5 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS83787.1 - 7.8e-39 134.0 23.7 4.4e-20 72.5 8.1 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ETS83787.1 - 1.7e-10 40.7 4.1 0.0005 19.6 0.3 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ETS83787.1 - 8.1e-08 31.9 1.3 0.0034 17.1 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 ETS83787.1 - 5e-07 29.5 0.0 0.022 14.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 ETS83787.1 - 5.4e-06 27.0 4.0 0.00037 21.0 0.1 2.9 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ETS83787.1 - 2.4e-05 24.3 0.2 0.046 13.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 ETS83787.1 - 2.7e-05 24.1 1.7 0.71 9.6 0.3 3.8 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ETS83787.1 - 4.6e-05 23.9 0.1 0.39 11.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 ETS83787.1 - 0.00031 20.8 0.6 0.049 13.7 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ETS83787.1 - 0.00059 19.9 1.7 0.77 9.8 0.0 2.7 2 0 0 2 2 2 2 Dynamin family T2SSE PF00437.20 ETS83787.1 - 0.00072 18.7 1.1 1.5 7.8 0.4 3.2 3 1 0 3 3 3 2 Type II/IV secretion system protein NB-ARC PF00931.22 ETS83787.1 - 0.0011 18.2 0.8 1.2 8.2 0.0 3.8 3 1 0 3 3 3 1 NB-ARC domain AAA_15 PF13175.6 ETS83787.1 - 0.0019 18.0 0.1 0.34 10.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS83787.1 - 0.0026 18.0 1.3 1.8 8.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 ETS83787.1 - 0.0032 17.6 0.1 0.0032 17.6 0.1 2.8 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_30 PF13604.6 ETS83787.1 - 0.0037 17.0 0.9 2.3 7.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 ETS83787.1 - 0.0044 16.4 0.5 0.26 10.6 0.0 2.6 3 0 0 3 3 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.6 ETS83787.1 - 0.0047 17.1 1.4 7.6 6.9 0.9 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.19 ETS83787.1 - 0.016 14.8 0.7 4.2 6.9 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 ETS83787.1 - 0.022 14.9 0.3 11 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ETS83787.1 - 0.022 15.2 0.9 9.8 6.6 0.1 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 ETS83787.1 - 0.041 13.6 0.1 6.8 6.3 0.1 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 ETS83787.1 - 0.044 13.3 0.2 3.1 7.3 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region DEAD PF00270.29 ETS83787.1 - 0.061 13.1 0.2 4.8 6.9 0.3 2.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase NACHT PF05729.12 ETS83787.1 - 0.062 13.2 0.8 5.1 7.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 ETS83787.1 - 0.064 13.8 0.0 17 6.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain GCIP PF13324.6 ETS83787.1 - 0.068 12.8 0.2 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting AAA_14 PF13173.6 ETS83787.1 - 0.07 13.2 0.1 13 5.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 ETS83787.1 - 0.08 12.7 0.1 16 5.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 ETS83787.1 - 0.12 11.8 2.3 0.94 8.9 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Septin PF00735.18 ETS83787.1 - 0.12 11.6 0.1 9 5.5 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_5 PF07728.14 ETS83787.1 - 0.12 12.4 0.5 32 4.5 0.0 3.2 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ETS83787.1 - 0.16 12.4 0.0 18 5.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 ETS83787.1 - 0.21 11.4 1.5 9.9 5.9 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 ETS83787.1 - 0.37 10.7 2.2 21 5.0 0.0 2.8 3 0 0 3 3 2 0 NTPase His_Phos_2 PF00328.22 ETS83788.1 - 4.1e-110 368.7 0.0 7.1e-110 367.9 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 ETS83788.1 - 3.7e-36 123.2 0.0 8e-36 122.1 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 ETS83788.1 - 1e-06 28.5 0.0 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.12 ETS83789.1 - 2.3e-84 282.6 1.0 3.4e-84 282.0 1.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 ETS83789.1 - 2.9e-13 50.0 27.1 4.9e-05 24.0 0.4 9.1 11 0 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS83789.1 - 1.4e-10 41.3 0.0 0.00022 21.5 0.0 5.7 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ETS83789.1 - 0.00011 21.0 0.3 1.6 7.3 0.0 3.8 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 ETS83789.1 - 0.001 17.7 0.0 0.0019 16.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 ETS83789.1 - 0.093 11.5 0.2 3.9 6.1 0.0 2.4 1 1 0 2 2 2 0 Nup133 N terminal like MFS_1 PF07690.16 ETS83790.1 - 5.5e-12 45.3 12.1 7.1e-12 44.9 12.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS83790.1 - 0.0009 18.2 1.8 0.001 18.1 1.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS83791.1 - 4.9e-16 58.6 24.4 1.4e-15 57.1 24.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily YrhK PF14145.6 ETS83791.1 - 0.28 11.1 4.9 1.6 8.7 0.9 2.8 2 0 0 2 2 2 0 YrhK-like protein CrgA PF06781.12 ETS83791.1 - 0.65 10.1 8.3 0.98 9.5 1.8 2.8 2 0 0 2 2 2 0 Cell division protein CrgA Ras PF00071.22 ETS83792.1 - 3.6e-40 137.2 0.0 7.1e-38 129.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 ETS83792.1 - 7.6e-32 110.0 0.0 1.1e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS83792.1 - 1.1e-10 41.2 0.0 1.7e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ETS83792.1 - 0.00017 21.7 0.0 0.0003 20.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 ETS83792.1 - 0.0051 16.3 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 ETS83792.1 - 0.068 13.5 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DLIC PF05783.11 ETS83792.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Gtr1_RagA PF04670.12 ETS83792.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RTP1_C2 PF10304.9 ETS83792.1 - 0.15 11.8 0.3 0.27 11.0 0.3 1.4 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 DUF588 PF04535.12 ETS83793.1 - 0.042 13.6 0.5 0.066 13.0 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF588) SAP PF02037.27 ETS83794.1 - 1.7e-14 53.2 1.0 2.9e-14 52.4 1.0 1.4 1 0 0 1 1 1 1 SAP domain Macoilin PF09726.9 ETS83795.1 - 0.15 10.5 3.5 0.19 10.3 3.5 1.1 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 ETS83795.1 - 0.42 9.8 2.6 0.59 9.3 2.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF5427 PF10310.9 ETS83795.1 - 2.4 7.0 14.8 4.6 6.1 14.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) RR_TM4-6 PF06459.12 ETS83795.1 - 4.6 7.0 10.5 9.3 6.0 10.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GATA PF00320.27 ETS83796.1 - 2.6e-29 100.5 17.8 3e-15 55.5 4.1 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 ETS83796.1 - 2.2e-07 30.2 4.0 0.0074 15.8 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ETS83796.1 - 3.7e-05 23.7 1.5 0.12 12.6 0.1 2.8 2 0 0 2 2 2 2 Zinc ribbon domain ArfGap PF01412.18 ETS83796.1 - 0.0013 18.8 3.4 0.37 10.9 0.2 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.12 ETS83796.1 - 0.0071 16.5 6.3 0.31 11.3 0.6 2.6 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 ETS83796.1 - 0.11 12.3 5.5 2.2 8.2 0.6 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DZR PF12773.7 ETS83796.1 - 0.15 12.1 15.1 3.5 7.7 2.4 3.2 1 1 2 3 3 3 0 Double zinc ribbon HypA PF01155.19 ETS83796.1 - 0.25 11.4 2.7 2.6 8.1 0.2 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 ETS83796.1 - 0.41 10.6 15.1 0.087 12.8 1.3 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 ETS83796.1 - 1.3 8.6 11.8 21 4.7 0.1 4.3 4 0 0 4 4 4 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 ETS83796.1 - 3.5 7.4 8.7 27 4.6 0.1 4.4 4 0 0 4 4 4 0 Rubredoxin metal binding domain ADK_lid PF05191.14 ETS83796.1 - 6.4 6.9 7.0 3.8 7.6 0.3 3.4 3 0 0 3 3 3 0 Adenylate kinase, active site lid COPI_assoc PF08507.10 ETS83797.1 - 6.9e-33 113.5 6.5 7.3e-33 113.4 6.5 1.0 1 0 0 1 1 1 1 COPI associated protein UCR_Fe-S_N PF10399.9 ETS83797.1 - 0.055 12.8 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF2583 PF10762.9 ETS83797.1 - 0.37 11.2 4.1 1.7 9.1 0.3 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2583) DUF3112 PF11309.8 ETS83798.1 - 2.5e-07 30.4 5.2 0.00027 20.5 0.1 2.3 1 1 0 2 2 2 2 Protein of unknown function (DUF3112) Metallophos PF00149.28 ETS83799.1 - 2.9e-37 129.2 0.5 3.6e-37 128.8 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ETS83799.1 - 0.027 14.9 0.0 0.052 14.0 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 ETS83799.1 - 0.094 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain F-box-like PF12937.7 ETS83800.1 - 8.2e-06 25.6 0.0 2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like PP_M1 PF03012.14 ETS83800.1 - 0.19 11.2 0.4 0.3 10.6 0.4 1.2 1 0 0 1 1 1 0 Phosphoprotein zf-C2H2_10 PF16588.5 ETS83801.1 - 0.0055 16.4 5.3 0.013 15.3 5.3 1.5 1 0 0 1 1 1 1 C2H2 zinc-finger F-box PF00646.33 ETS83801.1 - 0.018 14.9 0.5 0.042 13.7 0.5 1.6 1 0 0 1 1 1 0 F-box domain zf-CCHC_4 PF14392.6 ETS83801.1 - 0.077 12.7 2.4 0.18 11.6 2.4 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF5549 PF17703.1 ETS83801.1 - 0.2 11.3 4.5 0.35 10.5 4.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5549) zf-CCHC PF00098.23 ETS83801.1 - 2 8.7 5.6 5.8 7.2 5.6 1.9 1 0 0 1 1 1 0 Zinc knuckle Radical_SAM PF04055.21 ETS83802.1 - 3.2e-24 86.2 0.1 1.3e-23 84.2 0.1 2.1 1 1 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 ETS83802.1 - 6.2e-23 80.9 0.0 1.5e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.25 ETS83802.1 - 4e-10 40.1 0.3 4.1e-09 36.8 0.1 2.6 2 1 0 2 2 2 1 Flavodoxin DNA_pol_alpha_N PF12254.8 ETS83802.1 - 0.016 15.3 0.0 0.42 10.7 0.0 2.8 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal DUF4264 PF14084.6 ETS83802.1 - 0.036 13.7 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Flavodoxin_3 PF12641.7 ETS83802.1 - 0.14 11.8 0.0 0.47 10.1 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain MAS20 PF02064.15 ETS83803.1 - 7.1e-41 139.3 0.1 8.4e-41 139.1 0.1 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor Exo84_C PF16528.5 ETS83804.1 - 3.5e-72 242.5 2.6 3.5e-72 242.5 2.6 2.6 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 ETS83804.1 - 6.7e-17 61.4 1.6 6.7e-17 61.4 1.6 2.1 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 ETS83804.1 - 0.00029 20.9 2.1 0.01 15.9 0.0 3.1 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF4407 PF14362.6 ETS83804.1 - 0.78 9.0 11.4 0.94 8.8 8.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Prominin PF05478.11 ETS83804.1 - 1.4 6.8 7.2 0.31 8.9 1.6 2.1 2 0 0 2 2 2 0 Prominin DUF4047 PF13256.6 ETS83804.1 - 1.8 8.8 5.8 3.8 7.7 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) TSC22 PF01166.18 ETS83804.1 - 2.2 8.6 5.1 31 5.0 0.2 3.2 3 0 0 3 3 3 0 TSC-22/dip/bun family HMMR_C PF15908.5 ETS83804.1 - 7.2 6.9 9.1 0.43 10.8 2.3 2.4 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal APG6_N PF17675.1 ETS83804.1 - 8 7.0 20.8 0.087 13.4 5.2 3.1 3 0 0 3 3 3 0 Apg6 coiled-coil region HgmA PF04209.13 ETS83806.1 - 3.8e-125 417.9 0.0 4.7e-125 417.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase ABM PF03992.16 ETS83807.1 - 4.3e-08 33.2 0.5 0.0076 16.3 0.0 2.6 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase HET PF06985.11 ETS83808.1 - 4e-27 95.4 0.0 9.5e-27 94.1 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MCM PF00493.23 ETS83810.1 - 7.6e-98 326.1 0.3 1.2e-97 325.4 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ETS83810.1 - 1.1e-29 102.9 0.0 2e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ETS83810.1 - 2.9e-24 85.3 0.5 6.9e-24 84.1 0.5 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ETS83810.1 - 4.3e-09 36.9 0.0 1.5e-08 35.2 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ETS83810.1 - 4.4e-07 29.5 0.0 5.1e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 ETS83810.1 - 0.0016 18.3 0.0 0.0059 16.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ETS83810.1 - 0.012 15.3 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Utp14 PF04615.13 ETS83810.1 - 0.074 11.6 15.8 0.1 11.2 15.8 1.1 1 0 0 1 1 1 0 Utp14 protein Myc_N PF01056.18 ETS83810.1 - 3.5 7.4 9.3 7.1 6.4 9.3 1.5 1 0 0 1 1 1 0 Myc amino-terminal region Apt1 PF10351.9 ETS83810.1 - 9.2 5.0 10.1 16 4.2 10.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sec7 PF01369.20 ETS83811.1 - 3e-63 212.8 0.1 6.1e-63 211.8 0.0 1.6 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 ETS83811.1 - 4.8e-19 68.8 0.0 2.3e-17 63.3 0.0 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 ETS83811.1 - 0.00041 20.0 1.1 0.0021 17.8 0.6 2.2 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Anp1 PF03452.14 ETS83812.1 - 1.9e-113 378.2 0.1 3.4e-113 377.4 0.0 1.5 2 0 0 2 2 2 1 Anp1 SspB PF04386.13 ETS83812.1 - 0.28 11.1 4.1 0.54 10.1 4.1 1.4 1 0 0 1 1 1 0 Stringent starvation protein B UPF0564 PF10595.9 ETS83812.1 - 0.4 9.7 15.9 0.6 9.1 15.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 Rad54_N PF08658.10 ETS83812.1 - 0.49 10.5 8.8 0.43 10.7 7.4 1.6 1 1 0 1 1 1 0 Rad54 N terminal Ferlin_C PF16165.5 ETS83812.1 - 0.52 10.2 8.3 0.36 10.8 6.3 1.7 2 0 0 2 2 2 0 Ferlin C-terminus Smg8_Smg9 PF10220.9 ETS83812.1 - 1.2 7.3 7.2 1.4 7.1 7.2 1.1 1 0 0 1 1 1 0 Smg8_Smg9 MPM1 PF17234.2 ETS83812.1 - 4.1 7.6 12.8 7.4 6.8 12.8 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 HSP70 PF00012.20 ETS83812.1 - 5.3 5.1 10.4 8.8 4.4 10.4 1.2 1 0 0 1 1 1 0 Hsp70 protein MFS_1 PF07690.16 ETS83813.1 - 2.8e-39 135.0 40.9 5.1e-38 130.9 41.9 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS83813.1 - 2.4e-15 56.3 9.8 2.4e-15 56.3 9.8 2.8 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 ETS83813.1 - 1.2e-06 27.3 13.7 1.4e-06 27.0 13.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 ETS83813.1 - 9.6e-06 24.1 1.7 3.5e-05 22.2 0.8 2.2 2 0 0 2 2 2 1 BT1 family FAD_binding_3 PF01494.19 ETS83816.1 - 8.9e-20 71.2 0.2 1.6e-19 70.3 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS83816.1 - 6.4e-12 45.3 1.4 4.3e-05 22.9 0.1 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS83816.1 - 1.2e-10 41.5 4.8 1.5e-05 24.8 0.0 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS83816.1 - 1.9e-07 30.6 6.7 6.3e-06 25.5 1.2 2.2 1 1 1 2 2 2 2 FAD binding domain HI0933_like PF03486.14 ETS83816.1 - 4.1e-07 29.1 0.7 0.0016 17.3 0.4 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 ETS83816.1 - 1.4e-06 28.4 0.4 3.8e-06 27.0 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ETS83816.1 - 3.1e-05 23.0 3.6 0.002 17.1 0.2 2.7 2 1 1 3 3 3 2 Tryptophan halogenase Pyr_redox PF00070.27 ETS83816.1 - 3.7e-05 24.2 1.2 0.0055 17.2 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ETS83816.1 - 0.00028 20.3 0.8 0.52 9.5 0.1 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 ETS83816.1 - 0.00041 19.8 0.4 0.00067 19.1 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ETS83816.1 - 0.00074 18.7 0.4 0.00074 18.7 0.4 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ETS83816.1 - 0.0011 18.3 0.1 0.058 12.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS83816.1 - 0.0013 17.9 2.2 0.062 12.3 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 ETS83816.1 - 0.0064 15.7 0.4 0.013 14.7 0.4 1.5 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 ETS83816.1 - 0.016 15.1 0.1 0.03 14.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ETS83816.1 - 0.017 14.7 0.1 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.6 ETS83816.1 - 0.017 15.1 1.7 0.017 15.1 1.7 2.7 2 2 1 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 ETS83816.1 - 0.091 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.10 ETS83816.1 - 0.093 11.8 0.0 0.22 10.5 0.0 1.7 1 1 0 1 1 1 0 Squalene epoxidase Fungal_trans PF04082.18 ETS83817.1 - 1.8e-24 86.2 0.0 2.7e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS83817.1 - 3.5e-07 30.2 12.6 6.2e-07 29.4 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Haem_oxygenas_2 PF14518.6 ETS83817.1 - 0.1 12.4 0.2 0.21 11.4 0.2 1.5 1 0 0 1 1 1 0 Iron-containing redox enzyme ThiF PF00899.21 ETS83818.1 - 1.6e-20 73.5 0.0 3.5e-20 72.4 0.0 1.5 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 ETS83818.1 - 0.003 17.7 0.3 0.11 12.7 0.0 3.1 2 1 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle SUKH-3 PF14433.6 ETS83818.1 - 0.14 12.6 0.0 6.3 7.3 0.0 2.6 2 0 0 2 2 2 0 SUKH-3 immunity protein zf-RING_5 PF14634.6 ETS83819.1 - 5.1e-09 35.9 7.6 9.1e-09 35.2 7.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 ETS83819.1 - 3.8e-05 23.9 5.3 8.1e-05 22.9 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 ETS83819.1 - 8.9e-05 22.3 3.4 0.00018 21.3 3.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 ETS83819.1 - 0.00012 21.9 4.5 0.00027 20.7 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS83819.1 - 0.00022 21.2 3.7 0.00043 20.2 1.2 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ETS83819.1 - 0.00043 20.1 6.9 0.00087 19.1 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ETS83819.1 - 0.00089 19.1 8.1 0.0017 18.2 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ETS83819.1 - 0.00093 19.3 3.7 0.0018 18.4 3.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING S6OS1 PF15676.5 ETS83819.1 - 0.0045 15.5 1.9 0.0059 15.2 1.9 1.1 1 0 0 1 1 1 1 Six6 opposite strand transcript 1 family zf-RING_6 PF14835.6 ETS83819.1 - 0.021 14.7 2.3 0.046 13.6 2.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Mito_carr PF00153.27 ETS83819.1 - 0.027 14.4 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial carrier protein zf-MIZ PF02891.20 ETS83819.1 - 0.079 12.7 3.6 0.14 11.9 3.6 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Nudix_N_2 PF14803.6 ETS83819.1 - 0.093 12.7 3.0 0.3 11.0 3.0 1.8 1 1 0 1 1 1 0 Nudix N-terminal Fzo_mitofusin PF04799.13 ETS83819.1 - 0.12 11.9 3.4 0.18 11.3 3.4 1.3 1 0 0 1 1 1 0 fzo-like conserved region DZR PF12773.7 ETS83819.1 - 0.21 11.6 3.9 0.48 10.5 3.9 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-rbx1 PF12678.7 ETS83819.1 - 0.27 11.6 5.7 0.6 10.4 5.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-P11 PF03854.14 ETS83819.1 - 0.27 10.9 4.9 0.6 9.8 4.9 1.6 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 ETS83819.1 - 0.96 9.3 4.1 2.2 8.2 4.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FapA PF03961.13 ETS83819.1 - 4 5.9 6.3 5.4 5.5 6.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1451 PF07295.11 ETS83819.1 - 9 6.3 10.5 12 5.9 3.7 2.3 2 0 0 2 2 2 0 Zinc-ribbon containing domain GDA1_CD39 PF01150.17 ETS83821.1 - 8.5e-115 383.8 0.0 1.2e-114 383.3 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PPV_E2_C PF00511.17 ETS83821.1 - 0.15 12.2 1.5 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 E2 (early) protein, C terminal DUF775 PF05603.12 ETS83823.1 - 1.8e-49 168.0 0.0 7.8e-49 165.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF775) DUF4743 PF15916.5 ETS83824.1 - 2.1e-11 43.8 0.0 3.5e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 ETS83824.1 - 3.9e-08 33.4 0.1 8.6e-08 32.3 0.1 1.6 2 0 0 2 2 2 1 NUDIX domain RNA_pol_Rpb8 PF03870.15 ETS83825.1 - 4.2e-45 153.4 0.0 4.7e-45 153.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 ETS83825.1 - 5.2e-05 23.3 0.0 0.012 15.7 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G PAXNEB PF05625.11 ETS83826.1 - 3.7e-104 348.8 0.0 4.3e-104 348.6 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.17 ETS83827.1 - 1.2e-12 47.7 0.0 2.5e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF812 PF05667.11 ETS83827.1 - 0.07 12.0 0.1 0.072 12.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF782 PF05614.11 ETS83827.1 - 0.096 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF782) BCA_ABC_TP_C PF12399.8 ETS83827.1 - 0.26 11.3 1.0 1.4 8.9 0.5 2.3 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter zf-C3HC4_3 PF13920.6 ETS83828.1 - 1e-08 34.9 13.9 1.9e-08 34.0 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ETS83828.1 - 0.17 11.8 13.6 0.28 11.1 13.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RNase_PH PF01138.21 ETS83829.1 - 2.4e-27 96.1 0.1 4.4e-27 95.2 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 adh_short PF00106.25 ETS83830.1 - 1.2e-52 178.3 0.0 1.5e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS83830.1 - 1.3e-35 123.1 0.0 1.6e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS83830.1 - 2.2e-12 47.2 0.0 3.6e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS83830.1 - 0.016 14.4 0.0 0.12 11.5 0.0 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Lactococcin PF04369.13 ETS83831.1 - 0.13 12.4 0.1 11 6.3 0.0 2.9 2 1 1 3 3 3 0 Lactococcin-like family Trep_Strep PF09605.10 ETS83831.1 - 0.4 10.7 4.7 0.25 11.3 1.1 2.0 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF4244 PF14029.6 ETS83831.1 - 0.95 9.0 2.9 1.3 8.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) PAN_4 PF14295.6 ETS83832.1 - 0.27 11.2 5.2 0.55 10.2 5.2 1.5 1 0 0 1 1 1 0 PAN domain FAD_binding_4 PF01565.23 ETS83834.1 - 3.3e-28 98.2 0.6 5.7e-28 97.4 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Lipase_GDSL PF00657.22 ETS83836.1 - 1.3e-12 48.1 0.0 1.7e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ETS83836.1 - 3.1e-12 47.3 0.3 7.4e-12 46.0 0.1 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.6 ETS83836.1 - 0.03 14.4 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.16 ETS83837.1 - 2.4e-31 109.0 36.6 2.4e-31 109.0 36.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA PF00004.29 ETS83838.1 - 4.8e-51 172.6 0.0 1e-42 145.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ETS83838.1 - 9e-14 51.0 0.0 1.3e-07 31.3 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 ETS83838.1 - 1.5e-06 28.7 0.2 0.13 12.6 0.2 4.1 2 2 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.6 ETS83838.1 - 4.6e-06 26.7 0.0 0.0051 16.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ETS83838.1 - 2e-05 24.6 0.1 0.041 13.9 0.0 3.7 4 1 0 4 4 4 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ETS83838.1 - 0.00043 20.6 0.0 0.61 10.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_22 PF13401.6 ETS83838.1 - 0.00048 20.4 0.4 1.8 8.8 0.0 4.1 3 2 1 5 5 4 1 AAA domain NACHT PF05729.12 ETS83838.1 - 0.00088 19.2 0.5 0.049 13.5 0.1 2.8 2 1 1 3 3 3 1 NACHT domain AAA_28 PF13521.6 ETS83838.1 - 0.0016 18.7 0.0 0.25 11.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 ETS83838.1 - 0.0016 18.2 0.0 0.0059 16.4 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 ETS83838.1 - 0.0016 17.8 0.1 0.25 10.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 ETS83838.1 - 0.0017 18.5 0.0 0.028 14.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ETS83838.1 - 0.0017 18.5 0.0 0.36 11.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 ETS83838.1 - 0.0018 17.5 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) CDC48_N PF02359.18 ETS83838.1 - 0.0063 16.7 0.0 0.02 15.0 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Zeta_toxin PF06414.12 ETS83838.1 - 0.015 14.6 0.0 5.6 6.2 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin ATPase PF06745.13 ETS83838.1 - 0.027 13.8 0.9 12 5.2 0.1 3.2 2 1 1 3 3 3 0 KaiC MMR_HSR1 PF01926.23 ETS83838.1 - 0.029 14.4 0.1 0.076 13.1 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Rad17 PF03215.15 ETS83838.1 - 0.035 14.0 0.0 0.099 12.6 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 ETS83838.1 - 0.086 12.7 0.7 24 4.7 0.0 3.2 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 ETS83838.1 - 0.089 12.0 0.0 0.23 10.6 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_7 PF12775.7 ETS83838.1 - 0.1 12.1 0.2 6 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Ras PF00071.22 ETS83840.1 - 1.1e-64 217.0 0.0 1.3e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS83840.1 - 9.7e-34 116.2 0.1 1.4e-33 115.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS83840.1 - 3.5e-13 49.4 0.0 4.3e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ETS83840.1 - 2.4e-05 24.0 0.0 5.3e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ETS83840.1 - 0.00044 19.7 0.0 0.00055 19.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ETS83840.1 - 0.004 17.2 0.0 0.0067 16.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETS83840.1 - 0.0041 17.1 0.1 2.7 7.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 ETS83840.1 - 0.0086 15.5 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 ETS83840.1 - 0.042 14.3 0.0 9.5 6.7 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 ETS83840.1 - 0.068 12.7 0.0 0.33 10.5 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B NCA2 PF08637.10 ETS83841.1 - 4.8e-110 367.3 0.0 8.4e-110 366.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.13 ETS83842.1 - 7.6e-25 87.8 18.7 7.6e-25 87.8 18.7 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily EF-1_beta_acid PF10587.9 ETS83842.1 - 1.5 9.3 3.7 2.3 8.7 3.7 1.3 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Pterin_4a PF01329.19 ETS83843.1 - 2.8e-24 85.1 0.0 3.6e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Amidohydro_1 PF01979.20 ETS83844.1 - 5.5e-32 111.4 0.0 7.2e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS83844.1 - 4.5e-09 36.3 0.4 2.9e-06 27.1 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family bZIP_1 PF00170.21 ETS83845.1 - 8.9e-08 32.1 9.3 3.4e-07 30.3 9.3 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ETS83845.1 - 0.0077 16.3 10.1 4 7.6 10.1 2.3 1 1 0 1 1 1 1 Basic region leucine zipper Actin PF00022.19 ETS83846.1 - 3.7e-53 180.6 0.0 4.9e-51 173.6 0.0 2.2 1 1 0 1 1 1 1 Actin YL1_C PF08265.11 ETS83847.1 - 1.1e-14 53.8 0.1 3.3e-14 52.3 0.1 1.8 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Nbl1_Borealin_N PF10444.9 ETS83847.1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Got1 PF04178.12 ETS83848.1 - 2.3e-15 57.0 10.9 2.8e-15 56.7 10.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Profilin PF00235.19 ETS83849.1 - 1.1e-47 161.5 0.4 1.2e-47 161.4 0.4 1.0 1 0 0 1 1 1 1 Profilin Endotoxin_M PF00555.19 ETS83850.1 - 0.83 9.7 9.0 0.28 11.2 2.7 2.4 2 0 0 2 2 2 0 delta endotoxin Synaptobrevin PF00957.21 ETS83851.1 - 3.1e-14 52.5 0.3 4.5e-14 52.0 0.3 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 ETS83851.1 - 5.8e-12 45.5 0.0 1.3e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Herpes_UL36 PF03586.13 ETS83851.1 - 0.0084 15.5 0.1 0.47 9.7 0.0 2.1 2 0 0 2 2 2 2 Herpesvirus UL36 tegument protein DUF16 PF01519.16 ETS83851.1 - 0.16 12.5 2.1 0.22 12.0 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 Sec63 PF02889.16 ETS83852.1 - 2.7e-136 452.8 0.0 1.3e-78 263.8 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 ETS83852.1 - 3.4e-52 176.8 0.1 3.5e-26 92.0 0.2 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 ETS83852.1 - 9.5e-23 81.0 0.0 2.5e-11 43.9 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ETS83852.1 - 6.3e-16 58.7 0.1 2.5e-06 27.8 0.0 4.4 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 ETS83852.1 - 2.5e-07 30.6 0.1 0.027 14.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 ETS83852.1 - 5.8e-07 29.9 1.2 0.036 14.4 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.6 ETS83852.1 - 1.3e-05 25.6 0.3 0.0068 16.8 0.3 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 ETS83852.1 - 0.00084 19.1 0.2 6.3 6.5 0.0 4.4 5 0 0 5 5 5 1 IstB-like ATP binding protein AAA PF00004.29 ETS83852.1 - 0.00096 19.6 0.6 0.77 10.2 0.0 4.5 6 1 0 6 6 5 1 ATPase family associated with various cellular activities (AAA) Helicase_PWI PF18149.1 ETS83852.1 - 0.003 17.7 0.1 0.023 14.8 0.0 2.3 2 0 0 2 2 2 1 N-terminal helicase PWI domain T2SSE PF00437.20 ETS83852.1 - 0.018 14.1 0.0 0.67 9.0 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 ETS83852.1 - 0.15 12.5 0.2 11 6.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain TniB PF05621.11 ETS83852.1 - 0.16 11.3 1.3 24 4.3 0.2 3.7 4 0 0 4 4 4 0 Bacterial TniB protein DUF3365 PF11845.8 ETS83852.1 - 0.17 12.2 0.1 0.68 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) Yip1 PF04893.17 ETS83853.1 - 1.8e-12 47.3 16.5 2.8e-12 46.7 16.5 1.5 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 ETS83853.1 - 0.051 13.4 5.9 0.085 12.6 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) PAS_3 PF08447.12 ETS83854.1 - 1e-15 57.8 0.0 1.5e-11 44.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 ETS83854.1 - 5.8e-09 35.9 0.0 0.00012 22.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 ETS83854.1 - 5.9e-09 36.1 0.0 5.8e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.6 ETS83854.1 - 5.6e-06 26.5 0.0 2.5e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 ETS83854.1 - 0.00022 21.4 0.2 0.0035 17.6 0.0 2.7 3 0 0 3 3 3 1 PAS fold PAS_12 PF18095.1 ETS83854.1 - 0.012 15.3 0.0 0.72 9.5 0.0 2.1 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain WD40 PF00400.32 ETS83855.1 - 7.4e-14 51.9 12.9 1.3e-05 25.8 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS83855.1 - 0.031 14.6 0.1 0.43 10.9 0.0 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_I_TF PF04090.12 ETS83856.1 - 1.9e-11 43.8 0.0 7.5e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor Lin-8 PF03353.15 ETS83856.1 - 0.042 13.4 0.6 7.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist ETC_C1_NDUFA5 PF04716.14 ETS83857.1 - 6.6e-25 86.7 4.7 5.3e-23 80.6 0.1 2.6 3 0 0 3 3 3 2 ETC complex I subunit conserved region Ank_2 PF12796.7 ETS83858.1 - 1e-53 179.8 2.4 8e-17 61.6 0.4 6.3 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS83858.1 - 3.9e-47 158.0 7.8 2.8e-09 37.3 0.2 8.9 5 2 4 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 ETS83858.1 - 1.1e-45 152.1 15.3 5.4e-05 23.4 0.1 11.2 11 0 0 11 11 11 8 Ankyrin repeat Ank_3 PF13606.6 ETS83858.1 - 4.1e-41 134.3 11.8 0.00096 19.4 0.0 11.0 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 ETS83858.1 - 9.3e-36 121.4 14.4 8.2e-07 29.2 0.0 9.7 4 2 6 10 10 10 8 Ankyrin repeats (many copies) VCH_CASS14 PF18315.1 ETS83858.1 - 0.042 13.9 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Integron cassette protein VCH_CASS1 chain Sugar_tr PF00083.24 ETS83859.1 - 5.1e-69 233.3 23.7 6e-69 233.1 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS83859.1 - 1.6e-17 63.5 30.4 1.9e-10 40.2 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS83859.1 - 0.0036 15.8 11.5 0.12 10.8 2.4 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Tetraspanin PF00335.20 ETS83859.1 - 1.7 8.3 8.9 2.5 7.8 7.5 2.0 1 1 0 1 1 1 0 Tetraspanin family Zn_clus PF00172.18 ETS83860.1 - 5.8e-09 35.9 7.8 5.8e-09 35.9 7.8 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.27 ETS83861.1 - 7.8e-42 143.0 0.0 1.7e-20 73.9 0.0 2.9 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS83861.1 - 2.1e-32 112.9 29.0 2e-27 96.5 10.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ETS83861.1 - 5e-11 42.5 0.0 0.0017 17.8 0.1 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ETS83861.1 - 2.3e-06 28.1 3.7 0.00093 19.6 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 ETS83861.1 - 8.7e-05 22.5 3.8 3.4 7.4 0.0 4.2 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ETS83861.1 - 0.00028 21.2 0.9 0.088 13.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 ETS83861.1 - 0.00051 20.0 1.2 0.056 13.3 0.1 2.8 2 0 0 2 2 2 1 RsgA GTPase SbcCD_C PF13558.6 ETS83861.1 - 0.00083 19.5 1.3 0.18 12.1 0.1 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 ETS83861.1 - 0.0011 19.1 0.9 0.019 15.1 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_25 PF13481.6 ETS83861.1 - 0.0013 18.4 0.5 0.53 9.8 0.1 3.6 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 ETS83861.1 - 0.0018 18.3 0.3 1.6 8.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_7 PF12775.7 ETS83861.1 - 0.0022 17.6 0.2 0.12 11.8 0.0 2.7 3 0 0 3 3 2 1 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 ETS83861.1 - 0.018 14.0 0.8 0.66 8.8 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 ETS83861.1 - 0.029 14.8 0.8 5.3 7.5 0.1 3.6 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 ETS83861.1 - 0.048 12.8 0.6 0.36 9.9 0.2 2.3 2 0 0 2 2 2 0 PIF1-like helicase DUF815 PF05673.13 ETS83861.1 - 0.057 12.6 0.1 2 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dynamin_N PF00350.23 ETS83861.1 - 0.089 12.8 1.2 6.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.12 ETS83861.1 - 0.095 12.6 1.0 1.9 8.4 0.0 2.8 2 0 0 2 2 2 0 NACHT domain T2SSE PF00437.20 ETS83861.1 - 0.096 11.7 2.8 0.19 10.7 0.2 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 ETS83861.1 - 0.14 12.5 0.1 4 7.9 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 ETS83861.1 - 0.14 12.1 0.4 39 4.2 0.1 3.4 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 ETS83861.1 - 0.34 10.7 4.3 12 5.8 0.5 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 ETS83861.1 - 2.6 8.3 4.2 1.5 9.1 0.2 2.6 3 0 0 3 3 3 0 AAA domain DUF3328 PF11807.8 ETS83862.1 - 1.1e-05 25.3 0.0 1.4e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ligase_CoA PF00549.19 ETS83862.1 - 0.01 15.7 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 CoA-ligase DUF3328 PF11807.8 ETS83863.1 - 2e-35 122.6 0.0 2.8e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Cmc1 PF08583.10 ETS83863.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like HET PF06985.11 ETS83865.1 - 3.3e-23 82.7 0.0 5.5e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.23 ETS83867.1 - 2.2e-25 89.0 0.7 3.1e-25 88.5 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS83867.1 - 0.0084 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like BBE PF08031.12 ETS83868.1 - 0.0059 16.7 0.0 0.015 15.4 0.0 1.6 1 1 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 ETS83869.1 - 9e-26 90.5 0.0 2.2e-18 66.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS83869.1 - 2.6e-11 43.5 0.0 4.5e-09 36.2 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS83869.1 - 1.1e-05 25.5 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Tubulin_3 PF14881.6 ETS83869.1 - 0.033 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain GST_C PF00043.25 ETS83871.1 - 1.9e-09 37.6 0.0 1.1e-08 35.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ETS83871.1 - 9.1e-05 22.4 0.5 0.00017 21.5 0.2 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ETS83871.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Acetyltransf_7 PF13508.7 ETS83872.1 - 4e-06 27.2 0.0 0.13 12.7 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS83872.1 - 0.00078 19.7 0.2 0.007 16.6 0.2 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS83872.1 - 0.0041 17.1 0.0 0.018 15.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain TPR_19 PF14559.6 ETS83873.1 - 0.00029 21.3 0.3 0.25 11.9 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 ETS83873.1 - 0.0098 15.9 0.0 0.36 11.0 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ETS83873.1 - 0.015 15.6 1.6 0.24 11.7 0.5 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 ETS83873.1 - 0.12 12.0 0.0 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain MFS_1 PF07690.16 ETS83874.1 - 9.7e-30 103.7 13.8 9.7e-30 103.7 13.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily NAD_binding_6 PF08030.12 ETS83875.1 - 2.4e-18 66.7 0.0 4.2e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 ETS83875.1 - 3.6e-11 43.3 11.7 7.2e-11 42.3 11.7 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ETS83875.1 - 6e-09 36.0 0.0 1.5e-08 34.7 0.0 1.7 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 ETS83875.1 - 0.0015 19.2 0.0 0.33 11.6 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain MFS_1 PF07690.16 ETS83876.1 - 4.8e-15 55.3 40.1 9.9e-12 44.4 13.8 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS83876.1 - 2.4e-08 33.3 18.4 4.1e-08 32.5 18.4 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS83877.1 - 8.1e-32 110.5 60.1 8.1e-32 110.5 60.1 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS83877.1 - 4.4e-12 45.2 29.7 7.9e-12 44.4 29.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS83877.1 - 6e-10 38.6 9.8 6e-10 38.6 9.8 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 ETS83877.1 - 0.29 9.4 19.1 0.0059 15.0 3.9 3.2 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family DAPG_hydrolase PF18089.1 ETS83878.1 - 9.8e-06 25.3 1.6 1.5e-05 24.7 1.6 1.3 1 1 0 1 1 1 1 DAPG hydrolase PhiG domain HET PF06985.11 ETS83879.1 - 2.8e-19 69.9 0.0 6.8e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_76 PF03663.14 ETS83880.1 - 3.6e-102 342.6 21.5 4.5e-102 342.3 21.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 HPIP_like PF18524.1 ETS83880.1 - 0.81 9.5 3.4 24 4.8 0.1 3.7 3 0 0 3 3 3 0 High potential iron-sulfur protein like Myc_target_1 PF15179.6 ETS83882.1 - 0.00047 20.1 0.6 0.0008 19.4 0.6 1.4 1 0 0 1 1 1 1 Myc target protein 1 Amnionless PF14828.6 ETS83882.1 - 0.0062 15.4 0.0 0.0068 15.3 0.0 1.1 1 0 0 1 1 1 1 Amnionless HemY_N PF07219.13 ETS83882.1 - 0.019 15.2 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Colicin_V PF02674.16 ETS83882.1 - 0.022 14.7 0.2 0.029 14.4 0.2 1.2 1 0 0 1 1 1 0 Colicin V production protein DUF2062 PF09835.9 ETS83882.1 - 0.046 13.6 0.2 0.062 13.2 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) SKG6 PF08693.10 ETS83882.1 - 0.056 12.9 0.8 0.056 12.9 0.8 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain TMEM65 PF10507.9 ETS83882.1 - 0.062 13.3 0.1 0.092 12.7 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 65 TMEM206 PF15122.6 ETS83882.1 - 0.065 12.4 0.0 0.077 12.1 0.0 1.1 1 0 0 1 1 1 0 TMEM206 protein family Adeno_E3_CR2 PF02439.15 ETS83882.1 - 0.11 12.2 11.4 0.36 10.6 11.4 1.8 1 1 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM132D_C PF15706.5 ETS83882.1 - 0.15 11.8 0.0 0.33 10.8 0.0 1.6 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Podoplanin PF05808.11 ETS83882.1 - 7.1 6.7 6.9 14 5.7 6.9 1.7 1 1 0 1 1 1 0 Podoplanin Methyltransf_23 PF13489.6 ETS83884.1 - 1.3e-06 28.4 0.0 1.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS83884.1 - 0.0082 16.8 0.0 0.039 14.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS83884.1 - 0.015 15.1 0.0 4.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 ETS83884.1 - 0.077 13.7 0.0 0.29 11.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 ETS83884.1 - 0.1 13.3 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 ETS83885.1 - 1.9e-05 24.7 4.6 1.9e-05 24.7 4.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIOX_N PF14226.6 ETS83886.1 - 3.3e-15 56.9 0.5 6.6e-15 55.9 0.1 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS83886.1 - 2.5e-07 31.1 0.0 4.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ETS83887.1 - 5.1e-20 72.4 0.0 1.5e-19 70.9 0.0 1.7 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS83887.1 - 5.3e-11 42.9 0.0 9.4e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 ETS83888.1 - 5.9e-138 460.0 0.0 3.6e-69 233.4 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 ETS83888.1 - 1.5e-54 185.4 0.0 4.7e-32 111.3 0.0 3.1 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 ETS83888.1 - 4.3e-22 78.2 0.4 1.1e-10 41.7 0.1 3.6 4 0 0 4 4 4 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ETS83888.1 - 5.4e-06 27.3 0.1 0.0045 17.9 0.0 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain DNase_NucA_NucB PF14040.6 ETS83891.1 - 0.021 15.2 0.0 0.039 14.3 0.0 1.4 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB p450 PF00067.22 ETS83892.1 - 1.3e-72 245.0 0.0 1.7e-72 244.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SNF2_N PF00176.23 ETS83893.1 - 5.6e-74 249.0 0.0 8e-74 248.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 ETS83893.1 - 1.6e-23 82.5 0.0 3.4e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 ETS83893.1 - 1.1e-16 61.2 0.0 2.7e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS83893.1 - 0.00022 21.3 0.0 0.0006 19.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 ETS83893.1 - 0.00023 20.9 10.1 0.00047 20.0 10.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ETS83893.1 - 0.00087 19.1 6.7 0.0018 18.1 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS83893.1 - 0.0012 18.7 7.9 0.0021 17.9 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ETS83893.1 - 0.0043 17.3 11.3 0.01 16.1 11.3 1.7 1 0 0 1 1 1 1 Ring finger domain ERCC3_RAD25_C PF16203.5 ETS83893.1 - 0.02 14.1 0.2 0.02 14.1 0.2 1.5 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase UBA_4 PF14555.6 ETS83893.1 - 0.056 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain zf-RING_UBOX PF13445.6 ETS83893.1 - 0.11 12.6 9.7 0.21 11.6 9.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 ETS83893.1 - 0.7 9.9 9.7 3.7 7.6 9.8 2.2 1 1 1 2 2 2 0 zinc-RING finger domain SQS_PSY PF00494.19 ETS83894.1 - 8.8e-63 212.3 0.0 1.1e-62 211.9 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNARE_assoc PF09335.11 ETS83894.1 - 0.2 12.1 0.0 6.1 7.4 0.0 2.3 2 0 0 2 2 2 0 SNARE associated Golgi protein LDB19 PF13002.7 ETS83895.1 - 4.1e-38 131.0 0.3 3.5e-37 128.0 0.2 2.1 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.29 ETS83895.1 - 0.00034 20.7 0.0 0.0015 18.6 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF2235 PF09994.9 ETS83897.1 - 3.8e-83 279.2 0.0 4.7e-83 278.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MFS_1 PF07690.16 ETS83898.1 - 1.3e-14 53.9 25.6 2e-14 53.3 25.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF592 PF04574.13 ETS83898.1 - 0.21 11.4 0.2 0.65 9.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF592) adh_short_C2 PF13561.6 ETS83899.1 - 9.2e-33 113.7 0.7 1.7e-30 106.3 0.7 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS83899.1 - 4.3e-32 111.2 4.0 7.8e-21 74.4 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 ETS83899.1 - 1.1e-10 41.7 0.6 1.1e-10 41.7 0.6 2.6 2 1 0 2 2 2 1 KR domain Pyr_redox PF00070.27 ETS83899.1 - 0.028 15.0 0.5 0.055 14.0 0.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3Beta_HSD PF01073.19 ETS83899.1 - 0.069 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TRP PF06011.12 ETS83902.1 - 0.003 16.3 4.1 0.0034 16.2 4.1 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF2231 PF09990.9 ETS83902.1 - 0.011 16.1 0.5 0.014 15.8 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) Tyrosinase PF00264.20 ETS83904.1 - 3.7e-40 138.6 0.4 4.7e-40 138.2 0.4 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Fungal_trans PF04082.18 ETS83905.1 - 3.3e-23 82.1 0.8 5.8e-23 81.3 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 ETS83905.1 - 1.5e-08 34.6 13.3 0.00023 21.4 2.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ETS83905.1 - 6.3e-07 29.5 13.0 1e-06 28.9 6.8 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ETS83905.1 - 0.00037 21.1 13.2 0.03 15.1 2.3 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ETS83905.1 - 0.087 13.1 3.3 0.43 10.9 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding C1_4 PF07975.12 ETS83905.1 - 0.38 11.0 2.1 0.9 9.8 2.1 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain zf-met PF12874.7 ETS83905.1 - 1 9.8 5.4 0.63 10.5 1.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ArAE_2_N PF10337.9 ETS83906.1 - 3.6e-38 131.8 18.6 8e-30 104.3 0.0 3.9 4 1 1 5 5 5 3 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 ETS83906.1 - 5.8e-18 65.2 16.1 5.8e-18 65.2 16.1 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 ETS83906.1 - 3.3e-08 33.7 0.0 7.2e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ALMT PF11744.8 ETS83906.1 - 0.0024 16.8 3.6 0.0044 15.9 3.6 1.4 1 0 0 1 1 1 1 Aluminium activated malate transporter zf-met PF12874.7 ETS83907.1 - 6.1e-08 32.8 2.4 0.0036 17.6 0.2 3.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ETS83907.1 - 6.4e-07 29.2 7.3 0.014 15.4 0.4 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ETS83907.1 - 9.4e-07 29.0 28.8 0.00092 19.5 2.7 5.5 5 0 0 5 5 5 2 Zinc finger, C2H2 type NACHT PF05729.12 ETS83907.1 - 1.9e-05 24.6 0.0 7e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 NACHT domain zf-H2C2_2 PF13465.6 ETS83907.1 - 0.00027 21.2 0.4 0.00027 21.2 0.4 6.4 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ETS83907.1 - 0.00072 19.8 12.7 0.094 13.0 0.5 4.4 5 0 0 5 5 4 2 Zinc-finger double-stranded RNA-binding AAA_18 PF13238.6 ETS83907.1 - 0.0037 17.8 1.1 0.012 16.1 0.0 2.6 3 0 0 3 3 1 1 AAA domain zf-C2H2_4 PF13894.6 ETS83907.1 - 0.0038 17.9 23.9 0.023 15.5 1.1 5.3 5 0 0 5 5 4 2 C2H2-type zinc finger AAA_22 PF13401.6 ETS83907.1 - 0.039 14.2 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ETS83907.1 - 0.081 13.3 0.0 0.26 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 ETS83907.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase zf-C2H2_11 PF16622.5 ETS83907.1 - 0.15 11.8 4.6 2.8 7.8 0.1 2.9 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 ETS83907.1 - 1.5 9.5 10.7 0.37 11.5 4.3 3.2 3 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats C1_4 PF07975.12 ETS83907.1 - 1.9 8.8 8.8 1.4 9.2 2.1 3.6 3 1 1 4 4 4 0 TFIIH C1-like domain zf-Dof PF02701.15 ETS83907.1 - 2.6 8.3 11.0 0.28 11.3 0.8 2.9 2 1 1 3 3 3 0 Dof domain, zinc finger SNF2_N PF00176.23 ETS83908.1 - 2.5e-67 227.1 0.5 3.5e-67 226.6 0.5 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS83908.1 - 3.6e-15 56.3 0.1 1.2e-14 54.6 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ETS83908.1 - 1.2e-07 31.7 0.0 4e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 ETS83908.1 - 7.2e-06 26.1 0.0 1.7e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 ETS83908.1 - 2.7e-05 23.9 0.9 8.6e-05 22.3 0.9 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ETS83908.1 - 0.00043 20.2 5.1 0.00099 19.0 5.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ETS83908.1 - 0.00047 20.0 2.0 0.0014 18.4 2.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SWI2_SNF2 PF18766.1 ETS83908.1 - 0.0024 17.6 0.1 0.043 13.5 0.0 2.7 3 0 0 3 3 3 1 SWI2/SNF2 ATPase zf-C3HC4 PF00097.25 ETS83908.1 - 0.0032 17.3 5.2 0.0085 15.9 5.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 ETS83908.1 - 0.0069 15.3 0.1 0.028 13.3 0.1 1.8 1 1 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-RING_UBOX PF13445.6 ETS83908.1 - 0.016 15.2 2.6 0.042 13.9 2.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 ETS83908.1 - 0.072 13.3 3.8 0.17 12.0 3.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 ETS83908.1 - 0.2 11.6 12.0 0.16 11.8 2.4 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ETS83908.1 - 0.6 10.5 11.5 0.048 14.0 5.2 2.5 3 0 0 3 3 3 0 Ring finger domain zf-rbx1 PF12678.7 ETS83908.1 - 0.71 10.2 3.9 1.9 8.8 3.9 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 ETS83908.1 - 1.4 8.8 5.6 0.38 10.6 1.7 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PAN_4 PF14295.6 ETS83909.1 - 7.1e-06 25.8 0.6 2.2e-05 24.3 0.6 1.9 1 0 0 1 1 1 1 PAN domain MANEC PF07502.14 ETS83909.1 - 0.0018 18.5 0.1 0.0048 17.1 0.1 1.7 1 0 0 1 1 1 1 MANEC domain PAN_3 PF08277.12 ETS83909.1 - 0.096 12.5 1.9 0.34 10.7 1.9 1.9 1 0 0 1 1 1 0 PAN-like domain ADH_N PF08240.12 ETS83910.1 - 3.5e-29 100.9 0.2 7.2e-29 99.9 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS83910.1 - 4.1e-23 81.8 0.4 6.4e-23 81.2 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS83910.1 - 0.0001 23.4 0.2 0.00018 22.6 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 ETS83910.1 - 0.011 15.2 1.5 0.049 13.1 1.3 1.9 1 1 1 2 2 2 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 ETS83910.1 - 0.024 13.9 0.9 0.041 13.2 0.9 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ABC_membrane PF00664.23 ETS83911.1 - 9.8e-96 320.6 22.8 2.6e-52 178.2 3.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ETS83911.1 - 7.7e-67 224.0 0.0 3.3e-32 111.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ETS83911.1 - 3.4e-16 59.3 0.0 2e-05 24.2 0.0 4.2 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ETS83911.1 - 2.6e-08 33.5 0.0 0.0016 18.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ETS83911.1 - 3.1e-08 34.0 0.0 0.11 12.8 0.0 4.8 5 0 0 5 5 5 2 AAA domain RsgA_GTPase PF03193.16 ETS83911.1 - 1.3e-05 25.1 0.0 0.021 14.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ETS83911.1 - 1.5e-05 25.5 5.1 0.05 14.0 1.3 3.6 3 2 0 3 3 2 2 AAA ATPase domain APS_kinase PF01583.20 ETS83911.1 - 3e-05 23.9 0.1 0.0085 16.0 0.1 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.6 ETS83911.1 - 7.5e-05 22.5 0.5 0.063 13.0 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.6 ETS83911.1 - 9.7e-05 22.0 0.5 0.8 9.3 0.0 3.3 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 ETS83911.1 - 0.00036 20.7 0.1 0.68 10.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 ETS83911.1 - 0.00041 19.7 0.1 0.82 8.9 0.0 2.8 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.6 ETS83911.1 - 0.00043 20.8 0.0 1.3 9.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 ETS83911.1 - 0.00056 18.8 1.9 0.0096 14.8 0.0 3.0 4 0 0 4 4 4 1 Predicted ATPase of the ABC class SbcCD_C PF13558.6 ETS83911.1 - 0.00098 19.3 4.3 1.8 8.9 0.1 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 ETS83911.1 - 0.0016 18.3 1.4 1.4 8.6 0.0 3.8 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 ETS83911.1 - 0.0034 17.1 0.0 3.5 7.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 ETS83911.1 - 0.0035 17.4 0.0 4.9 7.3 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 ETS83911.1 - 0.0036 17.4 0.1 0.24 11.4 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 ETS83911.1 - 0.0044 17.5 0.0 0.54 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ETS83911.1 - 0.008 16.2 0.1 6.9 6.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 ETS83911.1 - 0.039 14.4 0.0 7.4 7.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 ETS83911.1 - 0.04 12.9 0.0 7.1 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) SRP54 PF00448.22 ETS83911.1 - 0.045 13.4 0.0 13 5.3 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_15 PF13175.6 ETS83911.1 - 0.045 13.4 0.0 0.66 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 ETS83911.1 - 0.064 13.0 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 ETS83911.1 - 0.065 12.7 0.0 5.3 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ETS83911.1 - 0.14 12.6 0.0 22 5.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase G-alpha PF00503.20 ETS83911.1 - 0.2 10.8 0.0 6.6 5.8 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit DUF3671 PF12420.8 ETS83911.1 - 1.1 9.4 2.5 1.3 9.2 0.1 2.4 2 1 1 3 3 1 0 Protein of unknown function CobD_Cbib PF03186.13 ETS83911.1 - 4.6 6.4 11.3 0.83 8.8 0.3 3.7 3 1 0 4 4 4 0 CobD/Cbib protein MFS_1 PF07690.16 ETS83912.1 - 1.2e-27 96.8 47.2 1.6e-25 89.8 46.2 3.1 1 1 0 1 1 1 1 Major Facilitator Superfamily AMP-binding PF00501.28 ETS83913.1 - 8.7e-104 347.4 0.0 1.1e-103 347.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS83913.1 - 2.5e-11 44.4 0.0 5.1e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HET PF06985.11 ETS83914.1 - 5.8e-21 75.4 0.2 6e-19 68.8 0.1 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 ETS83916.1 - 1.9e-32 112.6 25.3 8.8e-28 97.2 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS83916.1 - 2.1e-13 49.9 0.2 2.1e-13 49.9 0.2 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 ETS83916.1 - 4.1e-05 22.6 0.0 0.03 13.2 3.2 2.4 2 1 0 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 ETS83916.1 - 0.003 16.0 9.9 0.07 11.5 2.2 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector PAN_4 PF14295.6 ETS83917.1 - 1.5e-06 28.0 2.6 2.8e-06 27.1 2.6 1.5 1 0 0 1 1 1 1 PAN domain Phage_holin_3_6 PF07332.11 ETS83917.1 - 0.069 13.2 0.5 0.13 12.3 0.5 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III PAN_1 PF00024.26 ETS83917.1 - 0.09 12.8 0.3 0.22 11.5 0.3 1.6 1 0 0 1 1 1 0 PAN domain Pyr_redox_2 PF07992.14 ETS83918.1 - 2.2e-27 96.1 0.0 2.7e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS83918.1 - 1.1e-09 38.7 0.0 3.9e-07 30.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS83918.1 - 0.00018 21.5 1.1 6.6 6.7 0.0 4.0 4 0 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ETS83918.1 - 0.00062 19.1 2.7 0.031 13.5 0.3 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS83918.1 - 0.0016 17.6 0.6 0.022 13.8 0.2 2.5 2 1 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.24 ETS83918.1 - 0.005 16.5 0.3 2.2 7.7 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 ETS83918.1 - 0.016 15.6 0.2 0.045 14.2 0.0 1.9 2 1 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 ETS83918.1 - 0.021 13.7 0.1 1.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.6 ETS83918.1 - 0.029 13.5 0.1 4.5 6.3 0.0 2.5 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 ETS83918.1 - 0.043 12.5 1.6 7.2 5.2 0.5 3.0 2 1 0 3 3 3 0 HI0933-like protein NAD_binding_8 PF13450.6 ETS83918.1 - 0.067 13.4 0.1 17 5.7 0.0 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ETS83918.1 - 0.078 12.2 0.0 3.4 6.8 0.0 2.7 3 0 0 3 3 3 0 FAD binding domain Thi4 PF01946.17 ETS83918.1 - 0.13 11.5 0.3 1.2 8.3 0.1 2.4 3 0 0 3 3 3 0 Thi4 family Acetyltransf_8 PF13523.6 ETS83919.1 - 9.2e-45 151.9 0.5 1.3e-44 151.4 0.5 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1688 PF07958.11 ETS83920.1 - 7.7e-161 535.5 0.0 8.7e-161 535.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Apolipoprotein PF01442.18 ETS83921.1 - 3.9e-05 23.6 16.5 0.0065 16.4 13.3 3.3 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain Glyco_hydro_3_C PF01915.22 ETS83921.1 - 0.0014 18.7 0.1 0.0014 18.7 0.1 2.0 2 1 0 2 2 1 1 Glycosyl hydrolase family 3 C-terminal domain Globin PF00042.22 ETS83921.1 - 0.0024 18.4 1.6 0.68 10.5 0.0 3.7 1 1 2 3 3 3 1 Globin DUF4381 PF14316.6 ETS83921.1 - 0.11 12.7 4.5 1.4 9.1 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4381) TMP_2 PF06791.13 ETS83921.1 - 0.12 12.0 8.0 2.4 7.8 0.1 3.7 3 1 1 4 4 4 0 Prophage tail length tape measure protein Phasin_2 PF09361.10 ETS83921.1 - 0.2 11.9 16.5 12 6.3 0.1 5.3 3 1 2 5 5 5 0 Phasin protein BCAS2 PF05700.11 ETS83921.1 - 0.25 11.0 0.1 0.25 11.0 0.1 3.5 3 1 2 5 5 5 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF3994 PF13159.6 ETS83921.1 - 0.64 10.6 8.0 2.5 8.7 0.1 3.7 3 2 1 4 4 4 0 Domain of unknown function (DUF3994) HK97-gp10_like PF04883.12 ETS83921.1 - 1.6 9.8 17.3 0.62 11.1 0.7 4.7 2 1 3 6 6 6 0 Bacteriophage HK97-gp10, putative tail-component DUF948 PF06103.11 ETS83921.1 - 1.7 8.9 13.1 19 5.6 1.7 4.7 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) Peptidase_M41 PF01434.18 ETS83921.1 - 1.8 8.4 10.6 1.3 8.8 2.6 3.4 2 2 1 4 4 4 0 Peptidase family M41 ApoO PF09769.9 ETS83921.1 - 3.4 7.6 6.5 12 5.8 0.1 3.5 3 1 0 3 3 3 0 Apolipoprotein O SPOB_a PF14689.6 ETS83921.1 - 3.6 7.4 4.9 57 3.5 0.0 4.2 5 1 1 6 6 6 0 Sensor_kinase_SpoOB-type, alpha-helical domain YtxH PF12732.7 ETS83921.1 - 6.2 7.4 41.5 3.3 8.3 0.6 6.5 4 3 2 6 6 6 0 YtxH-like protein Transp_cyt_pur PF02133.15 ETS83922.1 - 2.9e-89 299.9 38.5 3.4e-89 299.7 38.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin GRDP-like PF07173.12 ETS83923.1 - 6.2e-20 72.3 0.8 2.1e-14 54.3 0.0 3.2 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like GTP_EFTU PF00009.27 ETS83924.1 - 2.2e-18 66.5 0.0 4.1e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 ETS83924.1 - 1.3e-10 41.5 0.2 6.4e-10 39.3 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 ETS83924.1 - 7.3e-05 23.1 0.5 0.0002 21.6 0.5 1.8 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 ETS83924.1 - 0.0021 18.1 0.2 0.0085 16.2 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETS83924.1 - 0.0049 16.8 0.5 3.4 7.6 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 ETS83924.1 - 0.0094 15.7 0.2 1.3 8.7 0.1 3.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 ETS83924.1 - 0.069 13.2 0.1 0.2 11.7 0.1 1.8 1 0 0 1 1 1 0 Dynamin family Roc PF08477.13 ETS83924.1 - 0.17 12.1 0.2 1.3 9.3 0.1 2.3 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase p450 PF00067.22 ETS83925.1 - 1.2e-72 245.1 0.0 1.4e-72 244.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.7 ETS83926.1 - 1.4e-18 68.3 0.2 3.4e-18 67.0 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS83926.1 - 5.1e-13 48.8 0.0 3.1e-12 46.3 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS83926.1 - 1.9e-11 44.1 0.0 5.5e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.20 ETS83926.1 - 5.8e-08 32.6 0.2 2.1e-06 27.6 0.0 2.5 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 ETS83926.1 - 0.00074 19.7 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 ETS83926.1 - 0.0014 18.4 0.1 0.0097 15.6 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein LIDHydrolase PF10230.9 ETS83926.1 - 0.0033 17.0 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PTPlike_phytase PF14566.6 ETS83926.1 - 0.0059 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 ETS83926.1 - 0.023 14.3 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 ETS83926.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Abhydrolase_2 PF02230.16 ETS83926.1 - 0.13 12.0 0.0 17 5.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase VirJ PF06057.11 ETS83926.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) LCAT PF02450.15 ETS83926.1 - 0.18 11.0 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF498 PF04430.14 ETS83927.1 - 3.4e-27 94.7 0.0 4.6e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Ribosomal_L34e PF01199.18 ETS83928.1 - 1.1e-41 141.0 1.1 1.4e-41 140.7 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e DZR PF12773.7 ETS83928.1 - 0.032 14.2 0.3 0.05 13.6 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon FhuF_C PF11575.8 ETS83928.1 - 0.42 10.6 5.3 1.7 8.7 0.3 2.8 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain PROCN PF08083.11 ETS83929.1 - 2e-235 781.0 7.8 2e-235 781.0 7.8 1.9 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 ETS83929.1 - 3.9e-127 422.6 0.9 8.2e-127 421.5 0.9 1.6 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 ETS83929.1 - 4.2e-89 296.6 1.9 1.4e-88 294.8 1.9 2.0 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 ETS83929.1 - 2.6e-80 267.7 2.4 6.7e-80 266.4 2.4 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 ETS83929.1 - 9.3e-72 239.4 0.1 2e-71 238.3 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 ETS83929.1 - 3.9e-47 158.5 0.3 1e-46 157.2 0.3 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 ETS83929.1 - 2.7e-43 146.8 0.0 9.9e-43 145.0 0.0 2.0 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 ETS83929.1 - 0.057 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ank_2 PF12796.7 ETS83930.1 - 3.6e-34 117.2 0.0 7.4e-12 45.7 0.0 4.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS83930.1 - 8e-28 96.1 3.1 2.3e-07 31.0 0.1 5.6 4 2 1 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS83930.1 - 7.5e-27 93.4 3.5 3.3e-06 27.5 0.1 5.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS83930.1 - 1.9e-25 86.1 0.8 0.0001 22.4 0.0 7.4 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 ETS83930.1 - 4.2e-23 80.7 4.6 0.0028 18.0 0.0 7.1 6 1 1 7 7 7 6 Ankyrin repeat zinc_ribbon_9 PF14369.6 ETS83931.1 - 0.041 14.1 0.7 0.12 12.6 0.7 1.8 1 0 0 1 1 1 0 zinc-ribbon Myb_DNA-bind_6 PF13921.6 ETS83932.1 - 6.9e-14 51.8 0.1 1.6e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ETS83932.1 - 7.6e-13 48.4 0.1 2.9e-05 24.2 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain AtuA PF07287.11 ETS83932.1 - 0.13 11.0 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA ApbA_C PF08546.11 ETS83933.1 - 2e-26 92.6 0.0 6.2e-26 91.0 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 ETS83933.1 - 3.5e-24 85.2 0.0 6e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF334 PF03904.13 ETS83933.1 - 0.072 12.6 0.3 0.11 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Mpv17_PMP22 PF04117.12 ETS83934.1 - 2.5e-08 34.0 3.3 6.5e-08 32.7 2.4 2.0 1 1 1 2 2 2 1 Mpv17 / PMP22 family K_channel_TID PF07941.11 ETS83934.1 - 0.029 14.8 3.5 0.084 13.3 3.5 1.8 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Lipase_GDSL PF00657.22 ETS83936.1 - 5.5e-06 26.5 0.0 5.8e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ETS83936.1 - 5.5e-05 23.6 0.1 9.9e-05 22.8 0.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MaoC_dehydrat_N PF13452.6 ETS83937.1 - 0.018 15.2 0.0 0.19 11.8 0.0 2.4 2 1 0 2 2 2 0 N-terminal half of MaoC dehydratase PD40 PF07676.12 ETS83938.1 - 0.00022 21.1 0.6 1.6 8.8 0.1 3.7 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Fungal_trans PF04082.18 ETS83939.1 - 5.4e-13 48.6 0.0 7.9e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dak1 PF02733.17 ETS83941.1 - 1.4e-102 342.8 1.3 2e-102 342.3 1.3 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 ETS83941.1 - 3.5e-44 150.8 1.0 6.1e-44 150.0 1.0 1.4 1 0 0 1 1 1 1 DAK2 domain F_bP_aldolase PF01116.20 ETS83942.1 - 5.2e-86 288.6 0.0 5.8e-86 288.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II adh_short_C2 PF13561.6 ETS83943.1 - 9.3e-59 198.8 3.6 1.2e-58 198.5 3.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS83943.1 - 4.1e-47 160.2 1.6 5.2e-47 159.8 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS83943.1 - 0.00027 20.9 0.1 0.00039 20.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 ETS83943.1 - 0.012 16.4 0.0 0.024 15.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SWIRM-assoc_3 PF16498.5 ETS83943.1 - 0.042 14.1 0.5 0.1 12.9 0.5 1.6 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal MFS_1 PF07690.16 ETS83944.1 - 5.9e-36 124.1 30.2 5.9e-36 124.1 30.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily PHO4 PF01384.20 ETS83944.1 - 0.067 12.2 3.5 0.13 11.3 3.5 1.5 1 1 0 1 1 1 0 Phosphate transporter family Trp_oprn_chp PF09534.10 ETS83944.1 - 0.51 10.1 2.7 0.91 9.3 1.3 2.2 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MFS_1_like PF12832.7 ETS83944.1 - 0.89 8.3 9.5 0.028 13.3 2.2 2.1 2 1 0 2 2 2 0 MFS_1 like family NAD_binding_10 PF13460.6 ETS83945.1 - 9.7e-07 28.8 0.0 1.1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Glycos_transf_N PF04413.16 ETS83945.1 - 0.039 13.6 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) PQQ_3 PF13570.6 ETS83946.1 - 0.23 12.0 9.7 14 6.3 0.1 5.6 6 0 0 6 6 6 0 PQQ-like domain FAD_binding_4 PF01565.23 ETS83949.1 - 8.7e-24 83.8 1.6 1.5e-23 83.1 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain Porin_5 PF16930.5 ETS83949.1 - 0.016 13.7 0.1 0.022 13.3 0.1 1.1 1 0 0 1 1 1 0 Putative porin Neil1-DNA_bind PF09292.10 ETS83949.1 - 0.026 14.5 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Endonuclease VIII-like 1, DNA bind BBE PF08031.12 ETS83949.1 - 0.056 13.6 0.7 0.11 12.7 0.1 1.9 2 0 0 2 2 2 0 Berberine and berberine like Fungal_trans PF04082.18 ETS83950.1 - 8.4e-34 116.8 1.0 1.4e-33 116.1 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS83950.1 - 2.7e-08 33.8 13.9 5.8e-08 32.7 13.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_5 PF00266.19 ETS83951.1 - 2.6e-27 95.8 0.0 8.9e-26 90.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 ETS83951.1 - 0.0054 16.0 0.0 0.014 14.6 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II AA_permease PF00324.21 ETS83952.1 - 4e-116 388.4 45.3 4.7e-116 388.2 45.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS83952.1 - 2.4e-29 102.5 46.6 3.2e-29 102.0 46.6 1.1 1 0 0 1 1 1 1 Amino acid permease Amino_oxidase PF01593.24 ETS83953.1 - 1.7e-09 37.5 0.0 2.5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ETS83953.1 - 5.9e-09 36.0 0.0 1.3e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS83953.1 - 0.00087 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS83953.1 - 0.0025 17.1 0.1 0.011 15.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS83953.1 - 0.0091 15.3 0.2 0.018 14.3 0.0 1.5 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 ETS83953.1 - 0.02 14.5 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ETS83953.1 - 0.025 13.9 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS83953.1 - 0.057 12.1 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 ETS83953.1 - 0.065 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 ETS83953.1 - 0.067 13.2 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ETS83953.1 - 0.15 11.3 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Reg_prop PF07494.11 ETS83954.1 - 0.00061 19.7 0.2 0.0039 17.2 0.2 2.4 2 0 0 2 2 2 1 Two component regulator propeller p450 PF00067.22 ETS83955.1 - 1.9e-63 214.8 0.0 2.3e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 ETS83956.1 - 5e-25 88.6 0.0 9.7e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.18 ETS83957.1 - 1.4e-08 34.7 6.2 2.6e-08 33.8 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS83957.1 - 0.00017 20.5 5.4 0.002 17.0 5.4 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3237 PF11578.8 ETS83958.1 - 7.3e-06 25.9 0.1 1.1e-05 25.3 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) Glyco_hydro_16 PF00722.21 ETS83959.1 - 1.4e-13 50.7 0.7 2.4e-13 49.9 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_3 PF13385.6 ETS83959.1 - 0.062 13.5 3.5 0.2 11.8 3.2 1.9 1 1 1 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily VIT_2 PF13757.6 ETS83959.1 - 0.12 12.3 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain NmrA PF05368.13 ETS83960.1 - 1.4e-22 80.4 0.0 1.8e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS83960.1 - 1e-07 32.0 0.4 4e-07 30.1 0.1 2.1 2 1 0 2 2 2 1 NAD(P)H-binding Tannase PF07519.11 ETS83961.1 - 4.6e-117 391.8 0.2 5.3e-117 391.6 0.2 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase p450 PF00067.22 ETS83962.1 - 3.3e-66 223.9 0.0 4e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SnoaL PF07366.12 ETS83963.1 - 0.00016 21.4 0.0 0.0002 21.2 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 ETS83963.1 - 0.00084 19.9 0.0 0.00093 19.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Asp PF00026.23 ETS83965.1 - 8.6e-74 248.8 14.4 1e-73 248.5 14.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS83965.1 - 6.5e-13 49.3 6.4 1.4e-09 38.5 3.4 3.1 1 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ETS83965.1 - 0.0017 19.0 0.9 2.3 8.9 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease Peptidase_M28 PF04389.17 ETS83966.1 - 4.4e-39 134.2 0.0 6.8e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ETS83966.1 - 1.3e-11 44.4 1.0 2.7e-11 43.3 1.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ETS83966.1 - 0.00043 20.0 0.0 0.00074 19.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1833 PF08875.11 ETS83966.1 - 0.028 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) SnoaL_2 PF12680.7 ETS83967.1 - 1.4e-06 28.9 0.1 3.3e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ETS83967.1 - 0.00047 19.9 0.0 0.00089 19.1 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Fungal_trans PF04082.18 ETS83968.1 - 1.9e-32 112.4 0.0 2.6e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS83968.1 - 0.00034 20.7 2.2 0.00034 20.7 2.2 2.2 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HpcH_HpaI PF03328.14 ETS83969.1 - 6.8e-39 133.3 0.0 9.3e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.6 ETS83969.1 - 0.018 14.5 0.3 0.13 11.7 0.1 2.4 2 1 0 3 3 3 0 Phosphoenolpyruvate phosphomutase MFS_1 PF07690.16 ETS83970.1 - 1.9e-38 132.3 41.9 1.7e-35 122.6 23.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily RseC_MucC PF04246.12 ETS83970.1 - 0.018 15.0 8.0 0.028 14.4 0.6 3.7 4 0 0 4 4 4 0 Positive regulator of sigma(E), RseC/MucC DUF998 PF06197.13 ETS83970.1 - 1.1 8.9 22.4 0.051 13.2 9.6 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF998) Wzz PF02706.15 ETS83970.1 - 9.1 6.7 10.9 3.5 8.0 0.4 4.0 4 1 0 4 4 4 0 Chain length determinant protein ADH_N PF08240.12 ETS83971.1 - 6.5e-28 96.8 2.6 6.5e-28 96.8 2.6 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS83971.1 - 2e-19 69.8 0.1 3.1e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS83971.1 - 1.4e-07 31.3 0.0 4.8e-06 26.2 0.0 2.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ETS83971.1 - 8.1e-06 26.9 0.0 1.5e-05 26.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ETS83971.1 - 0.064 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 ETS83971.1 - 0.096 13.4 0.1 0.2 12.4 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain PIN PF01850.21 ETS83971.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 PIN domain Aldo_ket_red PF00248.21 ETS83972.1 - 1.3e-37 129.6 0.0 2.1e-36 125.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SNF2_N PF00176.23 ETS83973.1 - 1.3e-57 195.1 0.0 2.3e-57 194.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 ETS83973.1 - 1.2e-48 165.6 0.3 1.3e-47 162.4 0.2 2.2 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 ETS83973.1 - 2.5e-16 60.0 0.0 6.5e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS83973.1 - 2.2e-08 34.3 0.0 4.2e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ETS83973.1 - 5.5e-05 23.0 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 ETS83973.1 - 0.0012 18.1 0.0 0.005 16.1 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 ETS83973.1 - 0.084 12.5 0.0 0.25 11.0 0.0 1.8 1 1 0 1 1 1 0 SWI2/SNF2 ATPase Mito_carr PF00153.27 ETS83974.1 - 1.7e-46 156.1 2.6 9.6e-17 60.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_2 PF02230.16 ETS83975.1 - 7.9e-24 84.7 0.0 2e-14 53.9 0.0 2.7 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 ETS83975.1 - 1.3e-05 25.0 0.0 7.3e-05 22.5 0.0 2.0 2 1 1 3 3 3 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 ETS83975.1 - 0.0052 16.1 0.0 0.83 8.9 0.0 2.7 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS83975.1 - 0.039 14.5 0.4 0.13 12.9 0.4 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 ETS83975.1 - 0.064 12.9 0.0 1.5 8.4 0.0 2.4 3 0 0 3 3 3 0 Putative esterase DUF2974 PF11187.8 ETS83975.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.21 ETS83975.1 - 0.17 11.4 0.0 4.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Acyl-CoA_dh_1 PF00441.24 ETS83977.1 - 9e-25 87.6 0.2 1.4e-24 87.0 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ETS83977.1 - 6e-23 81.7 0.1 1.3e-22 80.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ETS83977.1 - 2.4e-16 59.7 0.0 4.6e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ETS83977.1 - 1.8e-05 25.0 0.1 3.3e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2000 PF09391.10 ETS83978.1 - 0.031 14.2 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) ZapD PF07072.11 ETS83978.1 - 0.081 12.7 1.1 1.9 8.2 0.0 2.5 2 1 0 2 2 2 0 Cell division protein CorA PF01544.18 ETS83978.1 - 1.1 8.5 14.0 9.5 5.4 13.5 2.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.25 ETS83979.1 - 3.9e-18 65.8 0.0 7.4e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS83979.1 - 1.4e-13 50.7 0.0 2.7e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RTP PF02334.16 ETS83979.1 - 0.11 13.1 0.0 0.39 11.4 0.0 1.9 1 0 0 1 1 1 0 Replication terminator protein Sec34 PF04136.15 ETS83980.1 - 1.4e-49 167.9 0.6 3.4e-49 166.6 0.6 1.7 1 0 0 1 1 1 1 Sec34-like family Med11 PF10280.9 ETS83980.1 - 3.4 8.1 5.8 19 5.7 1.4 3.6 4 1 0 4 4 4 0 Mediator complex protein RCC1 PF00415.18 ETS83981.1 - 1.4e-28 99.2 4.7 5.9e-07 30.0 0.0 7.4 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ETS83981.1 - 5.3e-15 54.8 22.2 2.9e-10 39.7 0.1 6.3 8 0 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat DUF1459 PF07312.11 ETS83981.1 - 0.079 13.2 0.1 0.65 10.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) FRQ PF09421.10 ETS83982.1 - 3.3e-294 978.8 54.7 4.8e-294 978.2 54.7 1.1 1 0 0 1 1 1 1 Frequency clock protein DUF5082 PF16888.5 ETS83984.1 - 0.058 13.7 1.4 1.1 9.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Mito_carr PF00153.27 ETS83985.1 - 2e-60 200.7 2.1 1.8e-20 72.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RINT1_TIP1 PF04437.13 ETS83986.1 - 8.8e-166 552.7 0.0 1.9e-165 551.6 0.0 1.5 2 0 0 2 2 2 1 RINT-1 / TIP-1 family CRISPR_Cse2 PF09485.10 ETS83986.1 - 2.1e-05 25.1 4.3 0.00053 20.5 1.4 3.2 2 1 1 3 3 3 1 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF4164 PF13747.6 ETS83986.1 - 0.0018 18.5 13.0 0.0029 17.8 5.2 4.1 3 1 1 4 4 4 1 Domain of unknown function (DUF4164) TPR_MLP1_2 PF07926.12 ETS83986.1 - 0.043 13.9 5.9 0.052 13.6 1.1 2.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.11 ETS83986.1 - 0.057 13.2 1.0 0.25 11.2 0.8 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 RasGAP_C PF03836.15 ETS83986.1 - 0.092 12.9 1.8 0.46 10.6 0.8 2.5 2 0 0 2 2 2 0 RasGAP C-terminus DHR10 PF18595.1 ETS83986.1 - 0.21 11.6 6.0 0.05 13.7 1.7 2.3 2 0 0 2 2 1 0 Designed helical repeat protein 10 domain SseC PF04888.12 ETS83986.1 - 0.68 9.5 1.5 2 7.9 1.5 1.7 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Sec8_exocyst PF04048.14 ETS83986.1 - 1.3 8.9 4.8 2.5 8.0 0.3 3.4 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.12 ETS83986.1 - 7.5 6.6 6.4 2.3 8.3 0.3 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF4472 PF14739.6 ETS83986.1 - 7.9 7.3 9.4 0.65 10.8 1.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4472) DnaJ PF00226.31 ETS83987.1 - 4.9e-12 45.8 0.8 4.9e-12 45.8 0.8 2.4 2 0 0 2 2 2 1 DnaJ domain Glyco_hydro_18 PF00704.28 ETS83988.1 - 4.9e-11 42.9 0.0 5.7e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HetR_C PF18460.1 ETS83988.1 - 2.1 8.3 4.6 1.5 8.8 2.2 1.9 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain SNF2_N PF00176.23 ETS83989.1 - 1.9e-65 220.9 0.0 3.1e-65 220.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS83989.1 - 5.3e-22 78.3 0.0 1.6e-21 76.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS83989.1 - 1e-05 25.6 0.0 3.5e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ETS83989.1 - 7.9e-05 22.0 0.0 0.00017 20.9 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 ETS83989.1 - 0.0084 15.3 0.0 0.27 10.4 0.0 2.8 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ABC_tran_Xtn PF12848.7 ETS83989.1 - 7.5 6.7 10.5 45 4.2 5.6 3.2 3 0 0 3 3 3 0 ABC transporter Atg14 PF10186.9 ETS83989.1 - 9.1 5.3 7.5 16 4.4 7.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ribosomal_S11 PF00411.19 ETS83990.1 - 3.1e-46 156.3 1.6 3.8e-46 156.0 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_L30_N PF08079.12 ETS83991.1 - 4.5e-26 90.9 19.5 7.4e-26 90.2 19.5 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 ETS83991.1 - 7e-19 67.5 3.1 7e-19 67.5 3.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e EthD PF07110.11 ETS83992.1 - 0.00023 22.2 0.4 0.00039 21.5 0.4 1.5 1 1 0 1 1 1 1 EthD domain DUF1330 PF07045.11 ETS83992.1 - 0.078 13.3 0.3 5 7.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) DUF3237 PF11578.8 ETS83993.1 - 2.3e-13 50.2 0.0 2.4e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) MFS_1 PF07690.16 ETS83994.1 - 5.8e-33 114.3 26.4 5.8e-33 114.3 26.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily PIG-P PF08510.12 ETS83994.1 - 1.6 8.6 6.2 14 5.6 1.0 3.2 3 0 0 3 3 3 0 PIG-P PIP5K PF01504.18 ETS83995.1 - 5.5e-101 337.4 0.0 9.5e-101 336.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase COX6B PF02297.17 ETS83996.1 - 8e-22 77.3 4.6 1.1e-21 76.9 4.6 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prolamin_like PF05617.11 ETS83996.1 - 0.0093 16.1 0.2 0.013 15.6 0.2 1.2 1 0 0 1 1 1 1 Prolamin-like Pet191_N PF10203.9 ETS83996.1 - 0.041 14.2 0.6 0.11 12.8 0.6 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 SYS1 PF09801.9 ETS83997.1 - 9.4e-48 162.0 2.8 1.1e-47 161.8 2.8 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF2561 PF10812.8 ETS83997.1 - 2.1 8.4 7.1 3.7 7.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) Cu_amine_oxid PF01179.20 ETS83998.1 - 8.2e-126 420.2 4.1 1.1e-125 419.8 4.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 ETS83998.1 - 4.7e-32 109.6 0.6 1.4e-31 108.1 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 ETS83998.1 - 2.1e-05 24.7 0.0 5.8e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Aminotran_1_2 PF00155.21 ETS83999.1 - 2.8e-60 204.4 0.0 4e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ETS83999.1 - 0.044 12.7 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 ETS83999.1 - 0.18 11.1 0.0 0.38 10.0 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ETS83999.1 - 0.21 10.8 0.0 0.38 10.0 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AMP-binding PF00501.28 ETS84000.1 - 6.1e-48 163.5 0.0 8.2e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 ETS84000.1 - 4.3e-08 33.0 0.7 1.5e-07 31.2 0.1 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 ETS84000.1 - 9.2e-06 26.5 0.1 2.1e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ran_BP1 PF00638.18 ETS84001.1 - 9.5e-49 164.7 1.2 1.5e-48 164.0 1.2 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 ETS84001.1 - 0.0077 16.2 0.2 0.037 14.0 0.2 1.9 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 ETS84001.1 - 0.013 15.8 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 VID27 PH-like domain PS-DH PF14765.6 ETS84001.1 - 0.013 14.7 0.6 0.025 13.8 0.2 1.6 2 0 0 2 2 2 0 Polyketide synthase dehydratase Phosducin PF02114.16 ETS84003.1 - 4.7e-12 45.4 3.1 2.8e-11 42.9 0.3 2.6 2 1 0 2 2 2 1 Phosducin Anophelin PF10731.9 ETS84003.1 - 0.65 9.9 3.0 9.9 6.1 0.2 2.9 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito WD40 PF00400.32 ETS84004.1 - 8.3e-38 127.7 19.4 3.1e-07 31.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS84004.1 - 6.3e-14 52.0 0.1 0.00026 21.3 0.1 4.6 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS84004.1 - 0.00011 21.2 0.1 0.86 8.5 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ETS84004.1 - 0.00013 21.9 0.0 0.11 12.4 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ETS84004.1 - 0.0029 17.0 0.0 0.26 10.6 0.0 2.9 2 1 1 3 3 3 2 WD40-like domain A_deaminase PF00962.22 ETS84005.1 - 9.8e-30 104.0 0.0 1.1e-29 103.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 ETS84005.1 - 0.029 13.7 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family DUF4211 PF13926.6 ETS84006.1 - 2.4e-46 157.4 0.6 8e-46 155.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) OTCace PF00185.24 ETS84006.1 - 0.04 14.0 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain WD40 PF00400.32 ETS84007.1 - 2.6e-15 56.5 11.1 0.00027 21.6 0.2 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS84007.1 - 1.5e-07 31.6 0.1 0.053 13.8 0.0 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ETS84007.1 - 0.0046 16.3 0.0 0.0065 15.8 0.0 1.2 1 0 0 1 1 1 1 WD40-like domain Ge1_WD40 PF16529.5 ETS84007.1 - 0.015 14.3 0.0 0.14 11.1 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_S9 PF00326.21 ETS84007.1 - 0.19 11.2 1.6 1.6 8.1 0.8 2.3 2 1 0 2 2 2 0 Prolyl oligopeptidase family Lipase_GDSL_2 PF13472.6 ETS84008.1 - 4.2e-10 40.3 0.0 3.9e-09 37.2 0.0 2.3 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS84008.1 - 1.3e-07 31.8 0.0 1.6e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Acetyltransf_1 PF00583.25 ETS84009.1 - 1.2e-10 41.7 0.1 3.7e-10 40.1 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS84009.1 - 3.8e-08 33.3 0.0 8.2e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS84009.1 - 4.2e-08 33.5 0.1 8.9e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETS84009.1 - 4.8e-05 23.4 0.1 0.00023 21.2 0.2 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS84009.1 - 0.0001 22.2 0.1 0.00025 21.0 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 ETS84009.1 - 0.0032 17.6 0.0 0.0067 16.5 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_5 PF13444.6 ETS84009.1 - 0.011 16.4 0.0 6 7.7 0.0 2.5 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 ETS84009.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase FAO_M PF16350.5 ETS84009.1 - 0.16 12.3 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase central domain RasGEF PF00617.19 ETS84011.1 - 5.2e-60 202.7 0.1 1.1e-59 201.7 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ETS84011.1 - 4.4e-27 94.4 0.6 9.1e-27 93.4 0.6 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 ETS84011.1 - 1.5e-15 56.5 0.1 3.6e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ETS84011.1 - 6.7e-14 51.5 0.1 1.6e-13 50.3 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ETS84011.1 - 2.2e-13 49.7 0.1 5.3e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 ETS84011.1 - 0.00021 21.3 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 WW domain Fungal_trans PF04082.18 ETS84012.1 - 5.9e-16 58.3 1.7 9.2e-16 57.7 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 ETS84012.1 - 5.1e-08 33.0 12.1 1.1e-05 25.6 5.8 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 ETS84012.1 - 0.0047 17.3 13.6 0.3 11.6 4.3 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 ETS84012.1 - 0.02 15.6 0.7 2.6 8.7 0.1 2.9 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats ALG11_N PF15924.5 ETS84012.1 - 0.074 13.1 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 ALG11 mannosyltransferase N-terminus zf-C2H2_jaz PF12171.8 ETS84012.1 - 0.72 10.2 2.8 2 8.8 2.8 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 ETS84012.1 - 1.3 10.0 19.6 0.75 10.8 1.4 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Glyco_hydro_16 PF00722.21 ETS84013.1 - 5.6e-14 52.0 0.1 1.1e-13 51.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_64 PF16483.5 ETS84014.1 - 7e-142 473.1 0.5 8.4e-142 472.8 0.5 1.1 1 0 0 1 1 1 1 Beta-1,3-glucanase Sas10 PF09368.10 ETS84015.1 - 1.7e-28 98.9 11.4 1.7e-28 98.9 11.4 3.1 4 1 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 ETS84015.1 - 5.7e-11 42.9 8.6 7.4e-11 42.5 0.0 3.7 3 0 0 3 3 3 1 Sas10/Utp3/C1D family NRDE-2 PF08424.10 ETS84016.1 - 7.3e-93 311.2 3.6 6.5e-92 308.1 2.1 2.4 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 ETS84016.1 - 0.1 13.3 2.2 10 6.8 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 ETS84016.1 - 0.23 12.0 1.4 7.5 7.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Voltage_CLC PF00654.20 ETS84017.1 - 2.2e-87 293.6 23.6 2.2e-87 293.6 23.6 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel UCR_Fe-S_N PF10399.9 ETS84017.1 - 2.1 7.8 4.7 0.61 9.5 0.9 2.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal PIG-L PF02585.17 ETS84019.1 - 2.4e-29 102.6 0.0 3.9e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Cytochrom_B_N_2 PF13631.6 ETS84019.1 - 0.033 14.2 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB ATP13 PF12921.7 ETS84020.1 - 2.9e-20 72.2 0.4 8.6e-20 70.7 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ATPase expression LSM PF01423.22 ETS84021.1 - 5.7e-15 54.8 0.9 1e-14 53.9 0.9 1.5 1 1 0 1 1 1 1 LSM domain MFS_1 PF07690.16 ETS84022.1 - 2.8e-39 135.0 20.9 1.1e-38 133.1 21.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3169 PF11368.8 ETS84022.1 - 4.7e-05 23.0 2.1 0.34 10.4 0.3 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF3169) MFS_4 PF06779.14 ETS84022.1 - 9.6e-05 21.8 7.0 9.6e-05 21.8 7.0 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF5313 PF17240.2 ETS84022.1 - 0.02 15.3 0.3 0.12 12.8 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5313) EXS PF03124.14 ETS84022.1 - 0.17 11.1 7.2 0.76 9.0 3.4 2.8 2 1 0 2 2 2 0 EXS family COX2_TM PF02790.15 ETS84022.1 - 0.38 10.9 4.9 11 6.3 0.0 3.8 4 0 0 4 4 4 0 Cytochrome C oxidase subunit II, transmembrane domain DUF3112 PF11309.8 ETS84022.1 - 0.51 9.8 3.2 0.63 9.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3112) Bromodomain PF00439.25 ETS84023.1 - 9.4e-35 118.6 0.9 7.1e-18 64.5 0.0 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 ETS84023.1 - 2.6e-14 53.1 1.8 3.4e-14 52.7 0.8 1.8 2 0 0 2 2 2 1 BAH domain CDC45 PF02724.14 ETS84023.1 - 0.0006 18.2 6.0 0.0006 18.2 6.0 3.2 3 0 0 3 3 3 1 CDC45-like protein Phage_Gp23 PF10669.9 ETS84023.1 - 2.6 8.4 7.4 6.3 7.2 7.4 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) CagE_TrbE_VirB PF03135.14 ETS84026.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 2 0 0 2 2 2 0 CagE, TrbE, VirB family, component of type IV transporter system Glyco_hydro_17 PF00332.18 ETS84027.1 - 2.8e-06 27.2 1.3 1.8e-05 24.5 0.2 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 17 Aminotran_1_2 PF00155.21 ETS84028.1 - 6e-37 127.7 0.0 7.1e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ETS84028.1 - 0.0058 15.2 0.0 0.01 14.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 ETS84028.1 - 0.088 11.5 0.0 0.23 10.2 0.0 1.7 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Glucan_synthase PF02364.15 ETS84029.1 - 0 1377.7 0.0 0 1377.1 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 ETS84029.1 - 8.4e-43 145.8 0.5 2.5e-42 144.3 0.5 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 SprT-like PF10263.9 ETS84030.1 - 8.1e-30 103.0 4.1 1e-29 102.6 2.6 1.9 2 0 0 2 2 2 1 SprT-like family Zn_ribbon_SprT PF17283.2 ETS84030.1 - 2.8e-07 30.3 3.7 5.7e-07 29.3 3.7 1.6 1 0 0 1 1 1 1 SprT-like zinc ribbon domain zinc_ribbon_5 PF13719.6 ETS84030.1 - 0.71 9.7 4.7 1.7 8.5 4.7 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Mog1 PF04603.12 ETS84031.1 - 6.3e-37 127.0 0.0 7.5e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Rsa3 PF14615.6 ETS84032.1 - 3.9e-21 74.4 0.8 5.1e-21 74.0 0.8 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 FAM25 PF15825.5 ETS84032.1 - 0.15 12.4 1.0 0.26 11.7 1.0 1.3 1 0 0 1 1 1 0 FAM25 family UCH PF00443.29 ETS84033.1 - 1.3e-46 159.2 1.5 1.6e-46 158.9 1.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ETS84033.1 - 7e-29 101.4 4.5 7e-29 101.4 4.5 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 ETS84033.1 - 1.2e-06 28.7 0.5 1.2e-06 28.7 0.5 2.5 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein BLACT_WH PF17778.1 ETS84034.1 - 2.5e-15 56.1 0.1 1.1e-14 54.1 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 ETS84034.1 - 1.3e-14 54.7 1.3 4.2e-13 49.8 1.3 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS84034.1 - 4.6e-07 29.5 0.1 7.7e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain NACHT PF05729.12 ETS84034.1 - 0.0033 17.4 0.0 0.0097 15.8 0.0 1.7 2 0 0 2 2 2 1 NACHT domain ANAPC2 PF08672.11 ETS84034.1 - 0.16 12.5 0.2 6.5 7.3 0.1 2.4 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 Ytp1 PF10355.9 ETS84035.1 - 6.4e-113 376.6 6.6 9.1e-113 376.1 6.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 ETS84035.1 - 6e-33 112.8 4.2 6e-33 112.8 4.2 4.0 5 0 0 5 5 5 2 Domain of unknown function (DUF2427) Ca_hom_mod PF14798.6 ETS84035.1 - 0.13 11.4 0.0 0.29 10.2 0.0 1.6 1 0 0 1 1 1 0 Calcium homeostasis modulator NmrA PF05368.13 ETS84036.1 - 3.4e-16 59.5 0.0 4.4e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS84036.1 - 6.2e-15 55.6 0.0 1.1e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS84036.1 - 5.6e-14 52.2 0.0 1.4e-13 50.9 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS84036.1 - 7.7e-11 41.5 0.0 2.8e-10 39.7 0.0 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ETS84036.1 - 3.7e-07 29.8 0.1 6.2e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ETS84036.1 - 8.2e-07 28.4 0.0 7e-06 25.3 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 ETS84036.1 - 3.4e-05 23.4 0.0 7.1e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 ETS84036.1 - 0.0008 18.7 0.1 0.98 8.5 0.0 2.8 1 1 2 3 3 3 2 Male sterility protein adh_short_C2 PF13561.6 ETS84036.1 - 0.0013 18.3 0.1 0.0025 17.4 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS84036.1 - 0.052 13.5 0.0 0.46 10.4 0.0 2.1 2 0 0 2 2 2 0 KR domain ApbA PF02558.16 ETS84036.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Polysacc_synt_2 PF02719.15 ETS84036.1 - 0.2 10.8 0.0 0.52 9.4 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein PCI PF01399.27 ETS84037.1 - 1.8e-08 34.8 0.0 5.1e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 ETS84037.1 - 0.00012 21.5 0.1 0.00034 20.1 0.1 1.8 1 0 0 1 1 1 1 Rpn9 C-terminal helix tRNA-synt_1c PF00749.21 ETS84037.1 - 0.075 11.9 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Gaa1 PF04114.14 ETS84038.1 - 2.8e-169 564.3 1.2 3.4e-169 564.0 1.2 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.22 ETS84039.1 - 2.8e-13 50.1 7.6 2.8e-13 50.1 7.6 1.7 1 1 1 2 2 2 1 Rhomboid family DUF2434 PF10361.9 ETS84039.1 - 1.1 8.1 6.1 2.3 7.1 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2434) Aconitase PF00330.20 ETS84040.1 - 3.1e-146 488.0 0.0 3.9e-146 487.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ETS84040.1 - 2.3e-44 150.9 0.0 4.3e-44 150.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.8 ETS84041.1 - 5.7e-09 36.0 0.0 9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ETS84041.1 - 0.017 15.5 0.1 0.033 14.6 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DASH_Dam1 PF08653.10 ETS84042.1 - 1.2e-27 95.4 1.5 1.6e-27 95.0 1.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.20 ETS84043.1 - 2.5e-41 141.1 0.0 4.4e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ETS84043.1 - 2.8e-12 46.6 0.1 2.8e-12 46.6 0.1 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ETS84043.1 - 6.1e-08 32.9 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HIT PF01230.23 ETS84044.1 - 4.3e-22 78.7 0.1 5.5e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 ETS84044.1 - 1e-12 48.5 0.0 1.4e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 ETS84044.1 - 7.2e-05 22.6 0.2 0.0001 22.2 0.2 1.3 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 LppA PF16708.5 ETS84044.1 - 0.047 13.6 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium CSTF2_hinge PF14327.6 ETS84044.1 - 0.13 12.7 0.0 0.4 11.2 0.0 1.7 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 Gelsolin PF00626.22 ETS84045.1 - 1.9e-32 111.0 0.1 7.7e-10 38.5 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat OTU PF02338.19 ETS84046.1 - 4.7e-09 36.8 0.0 8.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-BED PF02892.15 ETS84046.1 - 0.086 12.9 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 BED zinc finger FmdA_AmdA PF03069.15 ETS84047.1 - 4.5e-179 595.1 0.0 5.7e-179 594.7 0.0 1.1 1 0 0 1 1 1 1 Acetamidase/Formamidase family EI24 PF07264.11 ETS84048.1 - 1.9e-15 57.5 1.3 2e-13 51.0 1.3 2.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.7 ETS84049.1 - 1.9e-39 134.8 0.0 4.7e-39 133.5 0.0 1.7 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 AAA_23 PF13476.6 ETS84050.1 - 0.024 15.1 5.2 0.036 14.6 5.2 1.2 1 0 0 1 1 1 0 AAA domain eIF-3_zeta PF05091.12 ETS84050.1 - 0.44 9.5 13.4 0.65 8.9 13.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 ETS84050.1 - 2.1 7.0 12.0 3 6.5 12.0 1.4 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 ETS84050.1 - 5.5 6.1 4.8 6.8 5.8 4.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 ETS84050.1 - 7.7 6.5 10.3 14 5.7 10.3 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAS_9 PF13426.7 ETS84051.1 - 5.1e-27 94.2 0.0 1.9e-17 63.4 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 ETS84051.1 - 9.6e-20 70.7 0.0 2.4e-11 43.7 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 ETS84051.1 - 3.7e-18 65.6 0.0 8.1e-07 29.0 0.0 3.7 3 1 0 3 3 3 3 PAS fold GATA PF00320.27 ETS84051.1 - 3.7e-15 55.2 8.9 9.9e-15 53.9 8.9 1.8 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.6 ETS84051.1 - 2.8e-11 43.6 0.0 0.00022 21.3 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 ETS84051.1 - 1.6e-08 34.8 0.0 0.0081 16.4 0.0 3.4 3 0 0 3 3 3 3 PAS fold PAS_2 PF08446.11 ETS84051.1 - 4.6e-05 24.0 0.0 0.18 12.5 0.0 3.5 3 0 0 3 3 3 1 PAS fold Importin_rep_4 PF18808.1 ETS84052.1 - 1.6e-31 108.5 0.7 1.6e-31 108.5 0.7 4.8 5 1 1 6 6 4 1 Importin repeat Importin_rep_5 PF18816.1 ETS84052.1 - 6.9e-19 67.9 1.3 6.9e-19 67.9 1.3 3.4 4 0 0 4 4 3 1 Importin repeat HEAT_EZ PF13513.6 ETS84052.1 - 1.2e-16 60.8 18.2 9.2e-09 35.6 0.4 8.9 7 1 2 9 9 8 4 HEAT-like repeat HEAT_2 PF13646.6 ETS84052.1 - 2.1e-16 60.1 11.5 7.1e-05 23.1 0.0 7.7 3 2 4 7 7 7 3 HEAT repeats HEAT PF02985.22 ETS84052.1 - 9.1e-15 53.5 16.8 0.011 16.0 0.0 11.0 11 0 0 11 11 9 3 HEAT repeat Vac14_Fab1_bd PF12755.7 ETS84052.1 - 1.3e-13 51.3 0.3 0.01 16.4 0.0 8.1 6 2 4 10 10 8 2 Vacuolar 14 Fab1-binding region Importin_rep_6 PF18829.1 ETS84052.1 - 5.1e-13 49.1 2.2 3.9e-12 46.3 0.7 2.9 2 0 0 2 2 2 1 Importin repeat 6 RIX1 PF08167.12 ETS84052.1 - 5.3e-08 32.8 0.0 0.00014 21.7 0.0 4.0 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 ETS84052.1 - 9.2e-08 32.3 1.3 0.0049 16.9 0.1 5.2 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 ETS84052.1 - 3e-07 30.3 1.1 0.52 9.8 0.1 5.6 5 1 0 6 6 6 2 CLASP N terminal MMS19_C PF12460.8 ETS84052.1 - 3.4e-07 29.7 3.4 9.4e-07 28.3 0.5 3.1 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 ETS84052.1 - 3.8e-06 26.9 1.7 0.095 12.6 0.1 5.9 7 1 0 7 7 6 1 Domain of unknown function (DUF3385) DRIM PF07539.12 ETS84052.1 - 8.1e-05 21.1 8.1 0.081 11.2 0.2 4.8 3 3 1 4 4 4 1 Down-regulated in metastasis Adaptin_N PF01602.20 ETS84052.1 - 0.00039 19.1 1.6 0.057 12.0 0.4 3.3 2 1 0 2 2 2 1 Adaptin N terminal region RTP1_C1 PF10363.9 ETS84052.1 - 0.00081 19.6 1.3 0.042 14.0 0.2 4.2 4 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_N PF03224.14 ETS84052.1 - 0.0017 17.7 1.1 1.1 8.4 0.1 3.3 3 0 0 3 3 3 2 V-ATPase subunit H DUF3535 PF12054.8 ETS84052.1 - 0.0033 16.7 2.1 0.014 14.7 0.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) Proteasom_PSMB PF10508.9 ETS84052.1 - 0.004 15.7 1.1 0.3 9.5 0.0 3.6 4 1 0 4 4 4 1 Proteasome non-ATPase 26S subunit Xpo1 PF08389.12 ETS84052.1 - 0.0082 16.2 0.0 3 7.9 0.0 3.3 2 0 0 2 2 2 1 Exportin 1-like protein Telomere_reg-2 PF10193.9 ETS84052.1 - 0.0094 16.4 3.3 0.037 14.5 1.1 3.1 3 1 0 3 3 2 1 Telomere length regulation protein Cnd3 PF12719.7 ETS84052.1 - 0.011 15.0 0.0 0.05 12.8 0.0 2.2 1 1 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain UNC45-central PF11701.8 ETS84052.1 - 0.02 14.9 5.2 1.4 8.9 0.4 4.1 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central IL34 PF15036.6 ETS84052.1 - 0.025 14.6 0.0 2.6 8.1 0.0 2.8 2 0 0 2 2 2 0 Interleukin 34 Arm PF00514.23 ETS84052.1 - 0.065 13.3 10.2 1.3 9.1 0.0 5.4 5 0 0 5 5 4 0 Armadillo/beta-catenin-like repeat Cyanate_lyase PF02560.14 ETS84052.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 Cyanate lyase C-terminal domain DUF4042 PF13251.6 ETS84052.1 - 0.12 12.1 0.0 4.1 7.1 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4042) CBS PF00571.28 ETS84053.1 - 2.2e-12 47.2 3.6 4e-05 24.0 0.0 3.8 4 0 0 4 4 4 2 CBS domain DUF3435 PF11917.8 ETS84054.1 - 1.2e-66 225.4 1.8 1.8e-66 224.8 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_int_SAM_4 PF13495.6 ETS84054.1 - 0.14 12.7 0.1 0.33 11.5 0.1 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Pol_alpha_B_N PF08418.10 ETS84054.1 - 0.28 11.1 3.3 0.96 9.4 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase alpha subunit B N-terminal Transthyretin PF00576.21 ETS84055.1 - 3.2e-05 24.6 0.0 5.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 HIUase/Transthyretin family AT_hook PF02178.19 ETS84055.1 - 0.0023 17.6 19.4 0.047 13.6 4.0 2.4 2 0 0 2 2 2 2 AT hook motif NAD_binding_6 PF08030.12 ETS84060.1 - 0.00021 21.4 0.0 0.001 19.2 0.0 1.9 1 1 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 ETS84060.1 - 0.00091 19.3 9.5 0.00091 19.3 9.5 2.8 2 1 0 2 2 2 1 Ferric reductase like transmembrane component MRP-S35 PF10246.9 ETS84060.1 - 0.078 12.9 0.0 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 Pkinase PF00069.25 ETS84061.1 - 1.4e-13 50.8 0.1 3.5e-13 49.5 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS84061.1 - 4e-11 42.7 0.0 5.5e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ETS84061.1 - 9.3e-07 28.4 0.1 1.4e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Melibiase PF02065.18 ETS84061.1 - 0.014 14.3 0.1 0.018 14.0 0.1 1.1 1 0 0 1 1 1 0 Melibiase Hid1 PF12722.7 ETS84062.1 - 0.7 8.0 10.7 0.98 7.5 10.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BUD22 PF09073.10 ETS84062.1 - 0.9 8.8 31.6 1.4 8.2 31.6 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 ETS84062.1 - 1.8 7.9 35.4 2.6 7.4 35.4 1.2 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 ETS84062.1 - 9.6 4.8 8.2 13 4.5 8.2 1.2 1 0 0 1 1 1 0 Presenilin DUF1641 PF07849.11 ETS84063.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) Trypan_PARP PF05887.11 ETS84064.1 - 0.0094 15.9 0.5 0.015 15.3 0.5 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) SDA1 PF05285.12 ETS84064.1 - 0.057 12.9 7.4 0.071 12.5 7.4 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 ETS84064.1 - 0.081 11.1 7.1 0.087 11.0 7.1 1.2 1 0 0 1 1 1 0 Nop14-like family NESP55 PF06390.12 ETS84064.1 - 0.25 10.9 4.4 0.41 10.2 4.4 1.4 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) NRIP1_repr_4 PF15690.5 ETS84065.1 - 0.02 14.2 0.8 0.032 13.6 0.8 1.2 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 4 HD_3 PF13023.6 ETS84066.1 - 5.8e-31 107.6 0.0 1.1e-30 106.8 0.0 1.4 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 ETS84066.1 - 6.1e-14 52.2 0.0 1.1e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 ETS84066.1 - 1.5e-06 28.4 0.1 6.2e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 HD domain ADK PF00406.22 ETS84066.1 - 0.00016 21.8 0.0 0.00038 20.6 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase DUF1878 PF08963.10 ETS84066.1 - 0.069 13.7 0.1 3.9 8.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1878) HD_3 PF13023.6 ETS84067.1 - 1.3e-46 158.5 0.2 1.7e-46 158.1 0.2 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 ETS84067.1 - 1.5e-13 50.9 0.0 2.2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 ETS84067.1 - 6.3e-05 23.2 0.0 0.00014 22.1 0.0 1.7 1 1 0 1 1 1 1 HD domain Mito_fiss_reg PF05308.11 ETS84068.1 - 0.056 13.5 2.4 0.085 12.9 2.4 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator SAPS PF04499.15 ETS84068.1 - 0.079 11.7 5.6 0.09 11.6 5.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CAP_N PF01213.19 ETS84068.1 - 0.19 11.2 6.2 0.24 10.8 6.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 ETS84068.1 - 5.2 7.1 9.8 7.9 6.5 9.8 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Methyltransf_23 PF13489.6 ETS84069.1 - 1.2e-06 28.5 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS84069.1 - 0.00014 21.7 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS84069.1 - 0.0015 19.1 0.0 0.0031 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS84069.1 - 0.0018 19.0 0.0 0.0037 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS84069.1 - 0.0037 17.9 0.0 0.007 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Glyoxal_oxid_N PF07250.11 ETS84069.1 - 0.14 11.3 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus ABC_tran_CTD PF16326.5 ETS84071.1 - 3.9e-05 23.8 5.3 0.00011 22.4 5.3 1.7 1 0 0 1 1 1 1 ABC transporter C-terminal domain SlyX PF04102.12 ETS84071.1 - 4.4e-05 24.0 5.4 0.00018 22.0 5.4 2.2 1 0 0 1 1 1 1 SlyX Prefoldin_2 PF01920.20 ETS84071.1 - 0.0072 16.3 7.8 0.2 11.6 2.0 3.3 2 1 1 3 3 3 1 Prefoldin subunit GAS PF13851.6 ETS84071.1 - 0.011 15.1 4.7 0.026 13.9 4.7 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 ETS84071.1 - 0.019 15.4 7.1 0.047 14.1 7.1 1.6 1 0 0 1 1 1 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 ETS84071.1 - 0.024 14.8 8.3 0.024 14.8 8.3 1.9 2 1 0 2 2 1 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 ETS84071.1 - 0.026 13.8 4.4 0.049 12.9 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.15 ETS84071.1 - 0.029 14.1 3.9 0.087 12.6 3.9 1.8 1 0 0 1 1 1 0 Septum formation initiator Cep57_MT_bd PF06657.13 ETS84071.1 - 0.039 14.4 7.3 0.066 13.7 6.3 1.9 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 BLOC1_2 PF10046.9 ETS84071.1 - 0.053 13.8 1.4 0.43 10.9 2.1 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mod_r PF07200.13 ETS84071.1 - 0.062 13.4 6.2 0.12 12.5 6.2 1.5 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF4795 PF16043.5 ETS84071.1 - 0.074 12.6 6.4 0.18 11.4 6.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) CENP-F_leu_zip PF10473.9 ETS84071.1 - 0.076 13.0 9.8 0.059 13.4 7.5 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.12 ETS84071.1 - 0.094 13.1 5.2 0.28 11.5 3.1 2.6 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) HAUS-augmin3 PF14932.6 ETS84071.1 - 0.1 12.2 9.0 0.031 13.9 6.2 1.5 2 0 0 2 2 1 0 HAUS augmin-like complex subunit 3 Csm1_N PF18504.1 ETS84071.1 - 0.19 12.1 5.9 0.23 11.8 3.5 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain Seryl_tRNA_N PF02403.22 ETS84071.1 - 0.19 11.9 5.3 0.074 13.3 2.6 1.7 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.14 ETS84071.1 - 0.23 11.8 2.8 0.48 10.8 2.8 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MCU PF04678.13 ETS84071.1 - 0.36 10.9 2.8 0.77 9.8 2.8 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF4337 PF14235.6 ETS84071.1 - 0.44 10.6 1.9 0.89 9.7 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) FapA PF03961.13 ETS84071.1 - 0.51 8.9 1.8 0.81 8.2 1.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4407 PF14362.6 ETS84071.1 - 0.56 9.5 2.5 0.97 8.7 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5320 PF17253.2 ETS84071.1 - 0.57 11.3 5.1 5.9 8.0 1.0 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5320) FlaC_arch PF05377.11 ETS84071.1 - 0.72 10.3 3.6 7.3 7.1 0.2 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 ETS84071.1 - 1.1 9.9 5.1 2.8 8.6 4.7 1.9 1 1 0 1 1 1 0 Initiation control protein YabA DUF16 PF01519.16 ETS84071.1 - 1.1 9.7 5.3 0.32 11.5 1.7 2.0 2 0 0 2 2 1 0 Protein of unknown function DUF16 Tup_N PF08581.10 ETS84071.1 - 3.7 7.9 8.8 17 5.8 1.5 3.0 2 1 1 3 3 3 0 Tup N-terminal CENP-Q PF13094.6 ETS84071.1 - 4.1 7.6 12.3 3 8.0 10.1 2.0 2 1 0 2 2 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1664 PF07889.12 ETS84071.1 - 4.9 7.2 5.3 5.3 7.1 1.8 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Laps PF10169.9 ETS84072.1 - 9.6 6.8 21.8 22 5.7 1.2 3.3 1 1 2 3 3 3 0 Learning-associated protein DUF3450 PF11932.8 ETS84074.1 - 3.8e-05 23.1 5.0 5.1e-05 22.7 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) TMCO5 PF14992.6 ETS84074.1 - 0.0036 16.9 0.6 0.004 16.8 0.6 1.1 1 0 0 1 1 1 1 TMCO5 family TMF_TATA_bd PF12325.8 ETS84074.1 - 0.01 16.0 3.2 0.014 15.6 3.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding HAUS-augmin3 PF14932.6 ETS84074.1 - 0.011 15.4 2.4 0.013 15.0 2.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 UPF0242 PF06785.11 ETS84074.1 - 0.012 15.7 4.8 0.014 15.5 4.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_1 PF00170.21 ETS84074.1 - 0.053 13.6 5.4 0.28 11.3 0.7 2.4 1 1 1 2 2 2 0 bZIP transcription factor HALZ PF02183.18 ETS84074.1 - 0.064 13.5 0.9 0.064 13.5 0.9 2.7 3 0 0 3 3 2 0 Homeobox associated leucine zipper BRE1 PF08647.11 ETS84074.1 - 0.12 12.4 6.4 1.3 9.1 6.4 2.1 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF2312 PF10073.9 ETS84074.1 - 0.15 11.7 5.0 0.13 11.9 3.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) GIT_CC PF16559.5 ETS84074.1 - 0.17 11.8 2.7 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor CorA PF01544.18 ETS84074.1 - 0.17 11.1 3.8 0.23 10.8 3.8 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3552 PF12072.8 ETS84074.1 - 0.26 10.7 8.9 0.35 10.3 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) APG6_N PF17675.1 ETS84074.1 - 0.34 11.5 5.9 0.54 10.8 5.9 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region FlaC_arch PF05377.11 ETS84074.1 - 0.42 11.1 6.7 6.4 7.3 0.5 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Fungal_TACC PF12709.7 ETS84074.1 - 0.48 10.9 4.7 0.86 10.1 0.6 2.4 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins CHD5 PF04420.14 ETS84074.1 - 0.77 9.6 3.4 1.2 9.0 3.4 1.4 1 1 0 1 1 1 0 CHD5-like protein MctB PF11382.8 ETS84074.1 - 1.4 8.6 4.9 9.9 5.8 0.7 2.1 1 1 1 2 2 2 0 Copper transport outer membrane protein, MctB Snf7 PF03357.21 ETS84074.1 - 2.2 7.9 7.4 2.1 7.9 6.4 1.5 1 1 0 1 1 1 0 Snf7 DUF2730 PF10805.8 ETS84075.1 - 0.0016 18.5 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) ABC_tran_CTD PF16326.5 ETS84075.1 - 0.0042 17.3 0.0 0.013 15.7 0.0 1.8 2 0 0 2 2 2 1 ABC transporter C-terminal domain Apolipoprotein PF01442.18 ETS84075.1 - 0.023 14.6 0.1 0.053 13.4 0.1 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain HAUS-augmin3 PF14932.6 ETS84075.1 - 0.034 13.7 0.0 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 NPV_P10 PF05531.12 ETS84075.1 - 0.066 13.7 0.1 0.17 12.4 0.0 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 ETS84075.1 - 0.087 12.9 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DrrA_P4M PF14860.6 ETS84081.1 - 0.0047 16.8 0.2 0.0072 16.1 0.2 1.3 1 0 0 1 1 1 1 DrrA phosphatidylinositol 4-phosphate binding domain DUF2564 PF10819.8 ETS84081.1 - 0.059 13.8 0.4 0.12 12.8 0.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2564) DUF3723 PF12520.8 ETS84083.1 - 5.8e-76 256.2 0.2 1.3e-71 241.9 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) YceD PF02620.17 ETS84084.1 - 0.12 12.5 0.1 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD Pkinase PF00069.25 ETS84085.1 - 1.4e-17 63.9 0.0 2.1e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS84085.1 - 2e-07 30.6 0.0 3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS84085.1 - 0.097 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 ETS84085.1 - 0.2 11.0 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PDDEXK_9 PF08011.11 ETS84086.1 - 0.051 13.5 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily SDA1 PF05285.12 ETS84089.1 - 0.45 9.9 6.9 0.51 9.7 6.9 1.1 1 0 0 1 1 1 0 SDA1 DUF4238 PF14022.6 ETS84091.1 - 0.19 11.2 3.5 0.28 10.7 3.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4238) TACC_C PF05010.14 ETS84093.1 - 0.042 13.6 0.3 0.052 13.3 0.3 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal LPD11 PF18824.1 ETS84093.1 - 0.098 12.8 1.5 0.11 12.6 0.4 1.7 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 DUF1499 PF07386.11 ETS84093.1 - 0.098 13.2 0.0 0.15 12.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1499) DUF1338 PF07063.13 ETS84094.1 - 1.8e-106 356.0 0.0 2.2e-106 355.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Aldedh PF00171.22 ETS84095.1 - 9.2e-149 495.9 0.0 1.1e-148 495.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3383 PF11863.8 ETS84095.1 - 0.0027 16.8 0.3 0.0038 16.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3383) REF PF05755.12 ETS84095.1 - 0.089 12.6 0.2 0.14 11.9 0.2 1.2 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Wtap PF17098.5 ETS84095.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family Helicase_IV_N PF12462.8 ETS84095.1 - 0.13 12.2 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal Abhydrolase_3 PF07859.13 ETS84096.1 - 5.6e-21 75.4 0.3 1.4e-20 74.0 0.3 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS84096.1 - 3.1e-15 56.1 0.4 1.3e-14 53.9 0.4 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ETS84096.1 - 3.8e-06 26.5 0.0 5.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 ETS84096.1 - 0.00085 18.3 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Ribonuc_L-PSP PF01042.21 ETS84097.1 - 4.9e-22 78.2 0.0 7.5e-22 77.6 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP DUF1833 PF08875.11 ETS84097.1 - 0.023 14.2 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) FAD_binding_3 PF01494.19 ETS84098.1 - 1.6e-18 67.1 0.9 6.2e-17 61.9 0.9 2.8 1 1 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 ETS84098.1 - 0.014 15.6 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.24 ETS84098.1 - 0.019 14.6 0.2 0.042 13.4 0.2 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS84098.1 - 0.043 14.0 0.0 0.087 13.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Cupin_2 PF07883.11 ETS84099.1 - 6.1e-15 54.7 0.0 3.2e-13 49.2 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Fungal_trans PF04082.18 ETS84100.1 - 2.1e-17 63.1 0.0 3.8e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS84100.1 - 1.2e-07 31.7 7.3 1.2e-07 31.7 7.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynamitin PF04912.14 ETS84100.1 - 0.0024 17.2 0.2 0.0037 16.6 0.2 1.2 1 0 0 1 1 1 1 Dynamitin Amidohydro_2 PF04909.14 ETS84101.1 - 1.8e-51 175.7 0.0 2.1e-51 175.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Sugar_tr PF00083.24 ETS84102.1 - 9e-101 337.9 24.2 1.1e-100 337.7 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS84102.1 - 1e-18 67.4 29.5 1e-18 67.4 29.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Cellulase PF00150.18 ETS84103.1 - 6.3e-18 65.2 0.5 1.3e-17 64.1 0.5 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_53 PF07745.13 ETS84103.1 - 0.017 14.1 0.1 1.3 7.9 0.0 2.7 2 1 0 3 3 3 0 Glycosyl hydrolase family 53 COesterase PF00135.28 ETS84104.1 - 9.6e-83 278.8 0.0 5.6e-72 243.3 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS84104.1 - 7.2e-05 22.7 0.0 0.00072 19.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS84104.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family TFB6 PF17110.5 ETS84105.1 - 4.7e-59 199.0 0.1 2.1e-57 193.6 0.1 2.1 1 1 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH Pox_Ag35 PF03286.14 ETS84105.1 - 0.1 12.4 3.3 0.17 11.7 3.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein zf-CCHC PF00098.23 ETS84106.1 - 3.2e-47 156.6 59.7 5.7e-08 32.5 2.5 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 ETS84106.1 - 8.6e-11 41.4 38.4 0.15 11.8 1.1 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.6 ETS84106.1 - 7.4e-07 29.0 42.3 0.011 15.6 0.0 6.9 4 2 3 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 ETS84106.1 - 2.6e-06 27.0 42.1 0.0066 16.1 1.0 7.1 4 2 3 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 ETS84106.1 - 0.034 14.0 50.0 0.051 13.4 0.4 6.9 6 1 1 7 7 7 0 Zinc knuckle zf-CCHC_2 PF13696.6 ETS84106.1 - 0.057 13.3 2.0 0.057 13.3 2.0 7.2 7 0 0 7 7 7 0 Zinc knuckle DUF3611 PF12263.8 ETS84107.1 - 0.0077 16.1 0.2 0.011 15.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) Apelin PF15360.6 ETS84107.1 - 0.047 14.3 2.5 0.047 14.3 2.5 3.5 3 1 0 3 3 3 0 APJ endogenous ligand DUF3278 PF11683.8 ETS84107.1 - 1.2 9.2 4.5 1.8 8.7 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) WD40 PF00400.32 ETS84108.1 - 2.2e-38 129.6 2.5 8.1e-07 29.7 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS84108.1 - 8.4e-12 45.2 0.1 0.0021 18.3 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 ETS84108.1 - 0.018 13.8 0.3 17 4.0 0.0 3.1 1 1 2 3 3 3 0 Nup133 N terminal like WD40_like PF17005.5 ETS84108.1 - 0.13 11.5 0.0 8.4 5.6 0.0 2.7 2 1 2 4 4 4 0 WD40-like domain OapA PF04225.12 ETS84108.1 - 0.15 12.1 0.0 0.47 10.6 0.0 1.9 2 0 0 2 2 2 0 Opacity-associated protein A LysM-like domain TRAPP PF04051.16 ETS84109.1 - 1.4e-35 122.1 0.1 1.7e-35 121.9 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 ETS84109.1 - 0.033 13.1 0.0 0.037 12.9 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A LisH PF08513.11 ETS84110.1 - 5.4e-05 23.0 1.0 9.3e-05 22.2 1.0 1.4 1 0 0 1 1 1 1 LisH Glyco_hydro_16 PF00722.21 ETS84111.1 - 2.9e-10 39.9 0.0 5e-10 39.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 ETS84111.1 - 1.5e-07 30.2 0.2 0.0051 15.3 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) GTP_EFTU PF00009.27 ETS84112.1 - 1.2e-51 175.0 0.0 1.9e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 ETS84112.1 - 1e-43 147.8 3.8 1.7e-43 147.1 3.8 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 ETS84112.1 - 1.8e-19 69.5 0.0 3.8e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ETS84112.1 - 9.2e-07 29.2 0.1 2.6e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 ETS84112.1 - 1.1e-06 28.3 0.0 3.1e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 ETS84112.1 - 1.8e-05 24.8 0.0 4.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 ETS84112.1 - 0.0014 18.4 0.0 0.0041 16.9 0.0 1.7 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 ETS84112.1 - 0.0035 17.4 0.0 0.0094 16.0 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 ETS84112.1 - 0.01 15.3 0.0 0.026 14.0 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 ETS84112.1 - 0.031 14.5 0.0 0.24 11.7 0.0 2.4 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 ETS84112.1 - 0.12 12.4 0.1 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Lipase_GDSL_2 PF13472.6 ETS84113.1 - 4.9e-10 40.1 0.2 6.1e-10 39.8 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS84113.1 - 0.00097 19.2 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ring_hydroxyl_A PF00848.19 ETS84115.1 - 3e-23 82.9 2.8 7.7e-11 42.4 1.7 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 ETS84115.1 - 4.3e-15 55.4 0.0 8.1e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FMO-like PF00743.19 ETS84116.1 - 4.3e-12 45.2 0.0 1.1e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ETS84116.1 - 2e-09 37.2 0.0 5.6e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS84116.1 - 1.9e-06 27.3 0.1 1.3e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ETS84116.1 - 0.0011 18.3 0.0 0.28 10.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 ETS84117.1 - 1.2e-16 60.7 27.1 2.7e-11 43.0 14.2 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF1656 PF07869.12 ETS84117.1 - 0.032 14.2 0.8 0.032 14.2 0.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) Phage_holin_5_2 PF16079.5 ETS84117.1 - 1.9 8.9 7.2 0.22 11.9 0.8 2.6 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V DAO PF01266.24 ETS84118.1 - 1.1e-35 123.9 0.1 1.3e-35 123.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS84118.1 - 4.6e-07 29.4 0.0 0.014 14.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS84118.1 - 5.5e-06 26.5 0.0 2.3e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ETS84118.1 - 0.00011 21.5 0.3 0.0048 16.0 0.1 2.5 2 1 1 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ETS84118.1 - 0.00015 21.0 0.4 0.002 17.3 0.4 2.1 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ETS84118.1 - 0.00025 19.9 0.0 0.25 10.0 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 ETS84118.1 - 0.00062 19.1 0.0 0.014 14.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS84118.1 - 0.0093 16.5 0.0 0.058 14.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 ETS84118.1 - 0.011 15.2 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NAD_binding_9 PF13454.6 ETS84118.1 - 0.015 15.3 0.2 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 ETS84118.1 - 0.023 14.7 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 ETS84118.1 - 0.024 13.9 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 ETS84118.1 - 0.026 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 ETS84118.1 - 0.053 13.8 0.0 0.42 10.9 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 ETS84118.1 - 0.07 13.6 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.17 ETS84118.1 - 0.07 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family GMC_oxred_N PF00732.19 ETS84118.1 - 0.075 12.4 0.1 1.6 8.1 0.1 2.2 2 0 0 2 2 2 0 GMC oxidoreductase FAD_binding_4 PF01565.23 ETS84119.1 - 9.6e-19 67.5 1.2 1.7e-18 66.7 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 ETS84119.1 - 0.051 13.2 0.1 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain MoCF_biosynth PF00994.24 ETS84119.1 - 0.078 12.6 0.0 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 Probable molybdopterin binding domain BBE PF08031.12 ETS84119.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like NmrA PF05368.13 ETS84120.1 - 0.018 14.6 0.1 0.39 10.2 0.1 2.1 2 0 0 2 2 2 0 NmrA-like family Hydantoinase_B PF02538.14 ETS84121.1 - 3.9e-210 698.6 0.1 5.2e-210 698.2 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 ETS84121.1 - 1.7e-90 303.3 0.0 3.2e-90 302.3 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ETS84121.1 - 1.4e-56 191.0 0.0 3.4e-55 186.5 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.16 ETS84122.1 - 3.4e-31 108.5 29.7 3.4e-31 108.5 29.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 ETS84123.1 - 2.9e-29 101.9 0.1 4.8e-29 101.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS84123.1 - 1.2e-05 25.3 12.2 2e-05 24.6 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.19 ETS84124.1 - 1.2e-39 135.5 0.0 1.7e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS84124.1 - 1.8e-09 37.4 0.0 2.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ETS84124.1 - 0.004 17.3 0.0 0.0082 16.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Peptidase_M20 PF01546.28 ETS84125.1 - 3.3e-18 66.1 0.2 5e-17 62.3 0.2 2.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ETS84125.1 - 1.6e-16 60.1 0.0 4e-16 58.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ETS84125.1 - 1.3e-05 25.0 0.0 2.8e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 2OG-FeII_Oxy PF03171.20 ETS84126.1 - 1.1e-09 38.7 0.0 1.8e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ETS84126.1 - 8.4e-07 29.8 0.0 1.6e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.16 ETS84127.1 - 0.073 12.0 0.1 0.097 11.6 0.1 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily MFS_1 PF07690.16 ETS84128.1 - 2e-24 86.2 26.9 9.4e-24 84.0 27.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily FMO-like PF00743.19 ETS84129.1 - 1.3e-10 40.3 0.4 2e-07 29.8 0.4 2.9 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ETS84129.1 - 2.8e-07 30.7 0.0 7.2e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS84129.1 - 4e-06 26.3 0.0 8.4e-05 22.0 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS84129.1 - 5.9e-05 22.4 0.0 0.036 13.2 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ETS84129.1 - 0.00024 20.5 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS84129.1 - 0.018 15.1 0.0 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding ARL2_Bind_BART PF11527.8 ETS84129.1 - 0.082 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART DUF1485 PF07364.12 ETS84129.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase family M81 DHDPS PF00701.22 ETS84130.1 - 1.3e-45 155.3 0.0 1.6e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 ETS84130.1 - 0.0094 15.4 0.6 0.028 13.9 0.5 1.6 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Aminotran_1_2 PF00155.21 ETS84131.1 - 5.2e-71 239.7 0.0 5.9e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II CwfJ_C_2 PF04676.14 ETS84131.1 - 0.19 12.7 0.0 0.4 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 2 Fungal_trans PF04082.18 ETS84132.1 - 1.1e-16 60.7 1.5 2.1e-16 59.7 1.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S29 PF02907.15 ETS84132.1 - 0.019 14.7 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease NAD_binding_2 PF03446.15 ETS84133.1 - 3.7e-22 79.2 0.1 5.8e-22 78.6 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ETS84133.1 - 2.1e-08 34.4 0.0 4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 ETS84133.1 - 0.0028 17.7 0.0 0.0053 16.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.18 ETS84134.1 - 0.0006 18.9 0.0 0.0068 15.5 0.0 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS84134.1 - 0.028 14.5 0.4 0.062 13.4 0.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AtuA PF07287.11 ETS84135.1 - 9.5e-121 402.8 0.0 1.1e-120 402.5 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA ADH_zinc_N PF00107.26 ETS84136.1 - 3.3e-10 40.0 0.2 7e-10 39.0 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS84136.1 - 3.2e-09 36.6 0.0 1.1e-06 28.5 0.0 2.7 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ETS84136.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Abhydrolase_6 PF12697.7 ETS84137.1 - 2.2e-13 51.4 0.0 2.8e-13 51.0 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS84137.1 - 3e-13 50.0 0.2 7.9e-11 42.1 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS84137.1 - 1.4e-07 31.1 0.1 5.5e-07 29.1 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 ETS84137.1 - 0.0061 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Bac_luciferase PF00296.20 ETS84138.1 - 7e-58 196.5 1.5 9.8e-58 196.0 1.5 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase LamB_YcsF PF03746.16 ETS84139.1 - 1.7e-57 194.9 0.1 2.5e-57 194.3 0.1 1.2 1 0 0 1 1 1 1 LamB/YcsF family MFS_1 PF07690.16 ETS84140.1 - 6.7e-28 97.6 21.7 8.5e-28 97.3 21.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ETS84140.1 - 1.1e-05 25.2 1.0 1.1e-05 25.2 1.0 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 AMP-binding PF00501.28 ETS84142.1 - 1.6e-74 251.0 0.0 2.2e-74 250.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS84142.1 - 1.6e-14 54.6 0.2 3.6e-14 53.5 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_hydro2_C5 PF18565.1 ETS84142.1 - 0.0031 17.3 0.1 0.0062 16.4 0.1 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 ADH_N PF08240.12 ETS84143.1 - 9.4e-20 70.5 0.9 1.8e-19 69.6 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS84143.1 - 5.6e-15 55.5 0.1 1.3e-14 54.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS84143.1 - 1.9e-09 38.7 0.0 6.2e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase FMO-like PF00743.19 ETS84144.1 - 2.9e-15 55.7 0.1 1.4e-14 53.5 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ETS84144.1 - 5.1e-12 45.7 0.0 6.2e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS84144.1 - 1.5e-11 44.1 0.0 2.3e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS84144.1 - 7.4e-07 28.6 0.0 0.0001 21.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ETS84144.1 - 2.9e-06 27.4 0.2 1.5e-05 25.1 0.1 2.3 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS84144.1 - 1.7e-05 24.6 0.3 0.0059 16.2 0.2 2.8 1 1 2 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS84144.1 - 0.0023 17.1 0.0 0.0047 16.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 ETS84144.1 - 0.0055 16.7 0.9 1.7 8.6 0.1 3.4 4 1 1 5 5 5 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 ETS84144.1 - 0.014 14.8 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS84144.1 - 0.032 12.9 0.1 0.096 11.4 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 ETS84144.1 - 0.042 13.2 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 ETS84144.1 - 0.077 12.2 0.1 0.37 10.0 0.1 1.9 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 ETS84144.1 - 0.086 12.9 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 ETS84144.1 - 0.11 11.5 0.0 0.47 9.5 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 ETS84144.1 - 0.13 12.9 0.3 2.8 8.6 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ETS84145.1 - 3e-17 62.2 0.0 2.5e-16 59.2 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ETS84145.1 - 1.3e-09 38.1 0.0 4e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS84145.1 - 6.8e-08 32.1 0.0 9.7e-06 25.0 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS84145.1 - 7.6e-05 22.0 0.0 0.0011 18.3 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ETS84145.1 - 0.00061 19.1 0.0 0.18 11.0 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS84145.1 - 0.0045 17.0 0.5 0.58 10.1 0.0 3.7 4 1 1 5 5 5 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 ETS84145.1 - 0.048 13.0 0.1 0.61 9.3 0.0 2.6 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase Fungal_trans PF04082.18 ETS84146.1 - 3.4e-11 42.7 0.0 7.4e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS84146.1 - 0.00013 22.0 12.0 0.00026 21.1 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ETS84147.1 - 6e-34 117.5 32.5 6e-34 117.5 32.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactamase_B PF00753.27 ETS84148.1 - 4.9e-09 36.5 0.9 7.4e-09 35.9 0.9 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS84148.1 - 0.012 15.1 0.0 0.027 14.0 0.0 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain adh_short PF00106.25 ETS84149.1 - 2.3e-26 92.5 0.0 3.2e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS84149.1 - 2.8e-23 82.7 0.0 4.3e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS84149.1 - 4.6e-06 26.6 0.0 0.0023 17.9 0.0 2.2 2 0 0 2 2 2 2 KR domain His_Phos_1 PF00300.22 ETS84150.1 - 6.1e-15 55.4 0.0 8.9e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Gmx_para_CXXCG PF09535.10 ETS84150.1 - 0.051 12.9 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) CTNNBL PF08216.11 ETS84151.1 - 9.3e-40 135.0 0.1 2.5e-38 130.4 0.0 2.9 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear GP46 PF07409.12 ETS84151.1 - 0.042 13.6 1.8 2.2 8.0 0.2 2.5 2 0 0 2 2 2 0 Phage protein GP46 DUF4524 PF15025.6 ETS84151.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) DUF3361 PF11841.8 ETS84151.1 - 0.68 9.9 5.8 3.9 7.4 1.5 3.3 2 2 2 4 4 4 0 Domain of unknown function (DUF3361) V-ATPase_G PF03179.15 ETS84152.1 - 5.3e-23 81.6 12.7 6.6e-23 81.2 12.7 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit RRF PF01765.19 ETS84152.1 - 0.015 15.3 6.1 0.016 15.2 6.1 1.2 1 0 0 1 1 1 0 Ribosome recycling factor DUF3314 PF11771.8 ETS84152.1 - 0.016 15.3 0.1 0.017 15.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3314) YusW PF14039.6 ETS84152.1 - 0.026 15.0 4.4 0.036 14.6 4.4 1.2 1 0 0 1 1 1 0 YusW-like protein V-ATPase_G_2 PF16999.5 ETS84152.1 - 0.026 14.9 10.0 0.032 14.6 10.0 1.1 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit SAPS PF04499.15 ETS84152.1 - 0.037 12.8 1.7 0.036 12.9 1.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2203 PF09969.9 ETS84152.1 - 0.055 14.2 3.8 0.07 13.8 3.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF87 PF01935.17 ETS84152.1 - 0.062 13.4 0.2 0.067 13.3 0.2 1.0 1 0 0 1 1 1 0 Helicase HerA, central domain Connexin PF00029.19 ETS84152.1 - 0.17 11.6 1.8 0.2 11.4 1.8 1.1 1 0 0 1 1 1 0 Connexin ECM11 PF15463.6 ETS84152.1 - 1.2 9.8 10.5 3 8.4 9.8 1.9 2 1 0 2 2 2 0 Extracellular mutant protein 11 BT1 PF03092.16 ETS84152.1 - 1.2 7.3 1.9 1.4 7.1 1.9 1.0 1 0 0 1 1 1 0 BT1 family Rotamase PF00639.21 ETS84152.1 - 3.1 8.8 8.3 7.2 7.6 8.3 1.5 1 1 0 1 1 1 0 PPIC-type PPIASE domain PET117 PF15786.5 ETS84153.1 - 2.4e-26 91.8 2.6 2.9e-26 91.5 2.6 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial RNA_pol_Rpb1_6 PF04992.14 ETS84153.1 - 0.015 15.1 0.4 0.017 15.0 0.4 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 Acetyltransf_7 PF13508.7 ETS84154.1 - 1.1e-09 38.5 0.0 1.9e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS84154.1 - 1.4e-09 38.0 0.1 2.3e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS84154.1 - 1.3e-08 35.1 0.0 1.5e-08 34.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ETS84154.1 - 1.6e-08 34.7 0.0 6.6e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ETS84154.1 - 0.00074 19.6 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 ETS84154.1 - 0.0025 17.7 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein PhyH PF05721.13 ETS84155.1 - 1.3e-09 38.6 0.0 9.7e-09 35.8 0.0 2.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF835 PF05763.12 ETS84156.1 - 0.0048 16.6 0.0 0.0089 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF835) E1-E2_ATPase PF00122.20 ETS84156.1 - 0.019 14.5 0.1 1.2 8.7 0.1 2.2 1 1 1 2 2 2 0 E1-E2 ATPase ABC2_membrane PF01061.24 ETS84157.1 - 1.3 8.4 10.6 1.8 7.9 10.6 1.1 1 0 0 1 1 1 0 ABC-2 type transporter Abhydrolase_6 PF12697.7 ETS84158.1 - 0.0047 17.6 6.8 0.0089 16.7 6.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family NACHT PF05729.12 ETS84159.1 - 4e-09 36.6 0.0 1.3e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 ETS84159.1 - 0.00031 21.2 0.7 0.0017 18.8 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 ETS84159.1 - 0.003 18.1 4.0 0.011 16.3 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 ETS84159.1 - 0.02 15.3 0.0 0.11 12.9 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cas9_b_hairpin PF17893.1 ETS84159.1 - 0.089 12.6 0.1 0.26 11.1 0.1 1.8 1 0 0 1 1 1 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain SNF2_N PF00176.23 ETS84160.1 - 2.3e-67 227.2 0.0 3.5e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS84160.1 - 7.1e-13 48.9 0.0 2.5e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS84160.1 - 1.8e-06 28.1 0.0 3.7e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 ETS84160.1 - 0.0013 18.5 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DEAD PF00270.29 ETS84160.1 - 0.0024 17.7 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase adh_short PF00106.25 ETS84161.1 - 5.3e-26 91.3 0.0 5.8e-21 74.9 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS84161.1 - 5.3e-15 55.6 0.2 6e-14 52.2 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS84161.1 - 9.3e-08 32.2 0.8 1.5e-07 31.6 0.2 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 ETS84161.1 - 0.00013 21.5 0.0 0.00029 20.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS84161.1 - 0.002 18.0 0.0 0.0041 17.0 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ETS84161.1 - 0.055 13.7 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ATP-grasp_5 PF13549.6 ETS84161.1 - 0.07 12.6 0.0 0.16 11.4 0.0 1.5 2 0 0 2 2 2 0 ATP-grasp domain Peptidase_S28 PF05577.12 ETS84162.1 - 4e-46 157.7 0.6 1.3e-45 156.0 0.6 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 ETS84162.1 - 1.3e-07 30.7 0.3 0.00097 17.9 0.1 2.2 2 0 0 2 2 2 2 PS-10 peptidase S37 DUF2920 PF11144.8 ETS84162.1 - 0.051 12.7 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) NEMO PF11577.8 ETS84163.1 - 0.0059 16.6 30.2 0.17 11.9 1.6 4.8 1 1 5 6 6 6 6 NF-kappa-B essential modulator NEMO AbiJ_NTD3 PF18860.1 ETS84163.1 - 0.006 16.1 5.4 0.059 12.9 0.5 2.9 1 1 2 3 3 3 2 AbiJ N-terminal domain 3 EHD_N PF16880.5 ETS84163.1 - 0.0068 16.3 0.9 3e+02 1.4 0.0 6.4 8 0 0 8 8 8 0 N-terminal EH-domain containing protein ACT_5 PF13710.6 ETS84163.1 - 0.15 11.9 9.5 96 2.9 0.1 6.0 7 0 0 7 7 7 0 ACT domain Tnp_22_trimer PF17489.2 ETS84163.1 - 0.73 9.9 22.3 2.8 8.0 0.2 6.1 6 2 1 7 7 7 0 L1 transposable element trimerization domain DUF501 PF04417.12 ETS84163.1 - 1.7 8.5 31.3 1.7 8.5 3.9 4.0 1 1 4 5 5 5 0 Protein of unknown function (DUF501) Gcn1_N PF12074.8 ETS84164.1 - 6.4e-118 394.1 3.0 6.4e-118 394.1 3.0 4.0 4 0 0 4 4 4 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 ETS84164.1 - 1.3e-32 109.0 41.1 0.035 14.4 0.1 23.1 25 0 0 25 25 23 8 HEAT repeat HEAT_EZ PF13513.6 ETS84164.1 - 4.3e-30 103.7 51.4 2.6e-07 31.0 0.0 20.2 19 3 5 24 24 21 9 HEAT-like repeat HEAT_2 PF13646.6 ETS84164.1 - 3.5e-24 85.0 52.6 8.7e-06 26.0 0.1 16.1 13 4 8 21 21 21 9 HEAT repeats Vac14_Fab1_bd PF12755.7 ETS84164.1 - 2.7e-16 59.9 0.0 0.29 11.8 0.1 9.0 6 2 1 7 7 7 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ETS84164.1 - 9.1e-15 55.1 4.2 1.4 8.9 0.2 10.7 8 2 1 11 11 11 3 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 ETS84164.1 - 7.6e-12 45.7 0.4 0.00023 21.4 0.0 5.8 5 1 0 5 5 5 2 Parkin co-regulated protein CLASP_N PF12348.8 ETS84164.1 - 4e-10 39.6 0.0 0.13 11.8 0.0 6.3 4 1 3 7 7 7 2 CLASP N terminal UME PF08064.13 ETS84164.1 - 3e-08 33.5 2.1 4.7 7.2 0.0 8.2 5 4 3 8 8 8 1 UME (NUC010) domain DUF3385 PF11865.8 ETS84164.1 - 3.5e-06 27.0 0.0 4.5 7.2 0.0 6.7 6 1 0 6 6 6 1 Domain of unknown function (DUF3385) TIP120 PF08623.10 ETS84164.1 - 2e-05 24.4 0.5 0.03 14.1 0.0 5.7 6 1 1 7 7 6 1 TATA-binding protein interacting (TIP20) DRIM PF07539.12 ETS84164.1 - 0.00014 20.3 7.7 0.18 10.1 0.9 4.3 3 1 1 4 4 4 2 Down-regulated in metastasis MMS19_C PF12460.8 ETS84164.1 - 0.00053 19.2 20.0 0.00068 18.9 0.1 7.1 7 2 1 9 9 9 1 RNAPII transcription regulator C-terminal Tti2 PF10521.9 ETS84164.1 - 0.00064 19.4 0.4 4.9 6.6 0.0 5.4 4 2 1 5 5 5 1 Tti2 family DUF937 PF06078.11 ETS84164.1 - 0.0026 18.4 4.3 25 5.5 0.0 6.1 6 1 0 6 6 6 0 Bacterial protein of unknown function (DUF937) TFCD_C PF12612.8 ETS84164.1 - 0.0065 16.3 2.6 0.077 12.8 0.0 3.8 3 1 0 3 3 3 1 Tubulin folding cofactor D C terminal FANCI_S2 PF14676.6 ETS84164.1 - 0.043 14.1 0.6 1.1 9.5 0.0 3.8 4 1 1 5 5 4 0 FANCI solenoid 2 Ipi1_N PF12333.8 ETS84164.1 - 0.054 14.1 0.3 1.2 9.8 0.1 3.5 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation TAF6_C PF07571.13 ETS84164.1 - 0.078 13.3 6.0 7.5 7.0 0.0 6.7 6 1 3 9 9 7 0 TAF6 C-terminal HEAT repeat domain RIX1 PF08167.12 ETS84164.1 - 1.9 8.2 9.2 0.68 9.6 0.3 4.8 5 1 0 5 5 5 0 rRNA processing/ribosome biogenesis Helicase_C PF00271.31 ETS84165.1 - 1.2e-16 61.1 0.0 2.7e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 ETS84165.1 - 4.4e-14 52.7 2.6 7.4e-14 52.0 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 ETS84165.1 - 1.7e-10 41.0 0.0 3.4e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ETS84165.1 - 2e-08 34.6 1.5 6.5e-07 29.7 0.1 3.5 3 0 0 3 3 3 1 AAA domain OB_NTP_bind PF07717.16 ETS84165.1 - 4.7e-08 33.3 0.1 9.8e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ABC_tran PF00005.27 ETS84165.1 - 0.019 15.5 0.2 0.14 12.7 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 ETS84165.1 - 0.047 14.0 0.0 0.34 11.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 ETS84165.1 - 0.091 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 KaiC Rad17 PF03215.15 ETS84165.1 - 0.091 12.7 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 ETS84165.1 - 0.41 11.1 0.0 0.41 11.1 0.0 2.7 4 0 0 4 4 4 0 AAA domain Cutinase PF01083.22 ETS84166.1 - 9.1e-42 143.0 0.2 1.1e-41 142.7 0.2 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 ETS84166.1 - 0.00036 20.1 0.2 0.00059 19.5 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 ETS84166.1 - 0.0017 18.2 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Lipase_3 PF01764.25 ETS84166.1 - 0.014 15.2 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 ETS84166.1 - 0.088 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 ETS84166.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Alpha_GJ PF03229.13 ETS84167.1 - 0.0019 18.7 2.3 0.0019 18.7 2.3 1.5 2 0 0 2 2 2 1 Alphavirus glycoprotein J MGC-24 PF05283.11 ETS84167.1 - 0.048 14.1 2.8 0.077 13.4 2.8 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Gram_pos_anchor PF00746.21 ETS84167.1 - 0.084 12.8 1.4 0.19 11.7 1.4 1.7 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Alkyl_sulf_dimr PF14863.6 ETS84168.1 - 2.2e-53 180.4 0.0 3.5e-53 179.8 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 ETS84168.1 - 2.7e-20 73.2 0.0 1.2e-19 71.1 0.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.6 ETS84168.1 - 1.9e-19 70.1 0.1 4e-19 69.1 0.1 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.7 ETS84168.1 - 0.00011 21.8 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TPR_16 PF13432.6 ETS84168.1 - 0.014 16.0 4.1 0.053 14.2 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 ETS84169.1 - 2.8e-46 158.1 56.2 1.2e-38 133.0 34.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_TTP_13 PF16463.5 ETS84169.1 - 0.16 11.5 0.0 0.61 9.6 0.0 1.8 2 0 0 2 2 2 0 Phage tail tube protein family Orf78 PF06024.12 ETS84169.1 - 0.52 10.6 1.7 8.3 6.8 0.0 3.0 3 0 0 3 3 3 0 Orf78 (ac78) FlgN PF05130.12 ETS84170.1 - 0.0099 16.4 1.6 0.0099 16.4 1.6 3.4 3 1 1 4 4 4 1 FlgN protein DUF4763 PF15960.5 ETS84170.1 - 0.012 15.0 1.1 0.012 15.0 1.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) TMPIT PF07851.13 ETS84170.1 - 0.24 10.6 2.3 1.3 8.2 1.7 2.1 2 0 0 2 2 2 0 TMPIT-like protein COG2 PF06148.11 ETS84170.1 - 1.3 9.1 4.4 2.3 8.3 0.6 2.9 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 LMBR1 PF04791.16 ETS84170.1 - 2 7.2 3.3 3.9 6.3 3.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein SMYLE_N PF18615.1 ETS84170.1 - 5.2 6.5 12.3 0.61 9.6 8.2 1.5 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Aconitase PF00330.20 ETS84171.1 - 3.6e-75 253.7 0.2 1.7e-73 248.2 0.2 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ETS84171.1 - 2.9e-13 50.3 0.0 5.3e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 ETS84171.1 - 0.0071 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Aconitate hydratase 2 N-terminus Fungal_trans_2 PF11951.8 ETS84172.1 - 9.5e-36 123.4 3.9 1.2e-35 123.0 3.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS84172.1 - 2.1e-08 34.1 9.9 2.1e-08 34.1 9.9 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pectate_lyase PF03211.13 ETS84173.1 - 4.2e-85 284.4 6.4 4.7e-85 284.2 6.4 1.0 1 0 0 1 1 1 1 Pectate lyase FMN_dh PF01070.18 ETS84174.1 - 1.3e-120 402.6 0.0 1.5e-120 402.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ETS84174.1 - 1.9e-07 30.4 0.0 3.8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 ETS84174.1 - 0.00018 21.0 0.1 0.0023 17.4 0.0 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein Glu_synthase PF01645.17 ETS84174.1 - 0.00024 20.4 0.1 0.00037 19.8 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 ETS84174.1 - 0.019 14.2 0.1 0.039 13.2 0.1 1.4 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase ThiG PF05690.14 ETS84174.1 - 0.021 14.1 0.1 0.18 11.0 0.1 2.1 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG NMO PF03060.15 ETS84174.1 - 0.037 13.4 0.1 0.055 12.9 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Aldedh PF00171.22 ETS84175.1 - 3.5e-182 606.0 0.5 4e-182 605.9 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GAIN PF16489.5 ETS84175.1 - 0.099 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain DUF1487 PF07368.11 ETS84175.1 - 0.17 11.3 0.0 0.86 9.0 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) DHDPS PF00701.22 ETS84176.1 - 9.9e-61 205.0 0.0 1.1e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Epimerase PF01370.21 ETS84177.1 - 5.4e-08 32.6 0.0 1.3e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS84177.1 - 1.3e-07 31.7 0.0 2.3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ETS84177.1 - 7.2e-07 28.5 0.0 1.6e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ETS84177.1 - 4.5e-06 26.0 0.0 6.8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ETS84177.1 - 1.1e-05 25.1 0.1 0.00015 21.4 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 ETS84177.1 - 0.00063 20.0 0.0 0.0022 18.2 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ETS84177.1 - 0.0011 19.2 0.0 0.003 17.8 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.12 ETS84177.1 - 0.0012 18.1 0.0 0.0031 16.7 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 ETS84177.1 - 0.0024 17.3 0.9 0.27 10.6 0.1 2.5 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 ETS84177.1 - 0.015 15.7 0.0 0.038 14.4 0.0 1.7 2 0 0 2 2 1 0 Semialdehyde dehydrogenase, NAD binding domain UvrD_C PF13361.6 ETS84177.1 - 0.12 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain MtrF PF09472.10 ETS84178.1 - 0.091 12.2 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Insulin_TMD PF17870.1 ETS84178.1 - 0.16 12.0 2.0 0.3 11.2 2.0 1.3 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment IDO PF01231.18 ETS84179.1 - 1.3e-164 548.1 0.0 1.5e-164 547.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase UEV PF05743.13 ETS84180.1 - 2.9e-37 127.2 0.0 4.7e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 ETS84180.1 - 1.2e-21 76.4 0.1 4.4e-21 74.6 0.0 1.9 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.26 ETS84180.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Methyltransf_23 PF13489.6 ETS84182.1 - 2.4e-22 79.5 0.0 3.5e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS84182.1 - 4.9e-10 40.0 0.0 9.4e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS84182.1 - 2.5e-08 34.5 0.0 1e-07 32.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS84182.1 - 5.1e-08 32.8 0.0 2.4e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS84182.1 - 3.6e-06 27.5 0.0 7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 ETS84182.1 - 0.0071 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 ETS84182.1 - 0.018 14.4 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ETS84182.1 - 0.038 13.5 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 ETS84182.1 - 0.05 13.1 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.19 ETS84182.1 - 0.082 13.0 0.0 0.66 10.1 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 ETS84182.1 - 0.11 11.8 0.0 0.84 8.9 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family RNA_pol_Rpb2_6 PF00562.28 ETS84183.1 - 1.3e-124 416.2 0.0 2.4e-124 415.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ETS84183.1 - 3.8e-56 189.8 0.0 1.4e-55 188.0 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 ETS84183.1 - 3.2e-47 160.6 0.0 6.7e-47 159.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 ETS84183.1 - 4.5e-33 113.5 0.1 9.6e-33 112.5 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 ETS84183.1 - 1.4e-25 89.2 0.1 4.6e-25 87.6 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 ETS84183.1 - 7e-25 87.4 0.7 2.4e-24 85.7 0.7 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 ETS84183.1 - 6.4e-24 84.0 0.4 1.6e-23 82.8 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 STE2 PF02116.15 ETS84185.1 - 1.6e-58 198.3 15.8 1.9e-58 198.0 15.8 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR PalH PF08733.10 ETS84185.1 - 0.32 10.0 8.7 0.43 9.5 8.7 1.2 1 0 0 1 1 1 0 PalH/RIM21 FAD_binding_3 PF01494.19 ETS84187.1 - 2.9e-20 72.8 0.0 7.2e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS84187.1 - 0.00019 21.6 1.1 0.00047 20.3 1.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ETS84187.1 - 0.011 14.7 0.3 0.19 10.6 0.4 2.1 2 0 0 2 2 2 0 Tryptophan halogenase DAO PF01266.24 ETS84187.1 - 0.017 14.7 1.4 0.04 13.5 1.4 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS84187.1 - 0.059 12.5 0.5 0.1 11.6 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain Abhydrolase_3 PF07859.13 ETS84188.1 - 1.6e-27 96.7 0.0 3.2e-25 89.3 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS84188.1 - 2.3e-06 27.1 0.0 5.5e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS84188.1 - 0.00083 19.1 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS84188.1 - 0.0014 19.2 2.5 0.0016 19.1 0.4 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 ETS84188.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Mt_ATP-synt_D PF05873.12 ETS84189.1 - 5.4e-21 75.1 3.4 6.6e-21 74.8 3.4 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) GIDA_assoc PF13932.6 ETS84189.1 - 0.023 14.9 1.4 0.029 14.5 1.4 1.1 1 0 0 1 1 1 0 GidA associated domain RPW8 PF05659.11 ETS84189.1 - 0.035 13.8 0.4 0.22 11.2 0.3 2.1 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Dor1 PF04124.12 ETS84189.1 - 0.066 11.9 3.0 0.085 11.5 3.0 1.1 1 0 0 1 1 1 0 Dor1-like family T5orf172 PF10544.9 ETS84189.1 - 0.13 12.8 0.2 0.33 11.5 0.1 1.6 1 1 1 2 2 2 0 T5orf172 domain DUF2408 PF10303.9 ETS84189.1 - 0.41 11.2 3.6 0.31 11.6 0.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) PCRF PF03462.18 ETS84189.1 - 0.52 10.2 4.4 0.68 9.8 4.4 1.2 1 0 0 1 1 1 0 PCRF domain THOC7 PF05615.13 ETS84189.1 - 1 9.6 7.4 2.5 8.4 1.6 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 NAC PF01849.18 ETS84190.1 - 3.7e-24 84.5 0.3 1.3e-23 82.7 0.1 2.0 2 0 0 2 2 2 1 NAC domain HHH PF00633.23 ETS84190.1 - 0.077 12.9 0.1 9.3 6.3 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif SPT6_acidic PF14632.6 ETS84190.1 - 1.5 9.4 15.6 0.16 12.5 6.6 2.2 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Ribosomal_L14e PF01929.17 ETS84191.1 - 4.3e-32 110.4 4.8 6.4e-32 109.9 4.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 ETS84191.1 - 0.00043 20.1 1.0 0.00069 19.5 0.0 1.9 2 0 0 2 2 2 1 KOW motif AMP-binding PF00501.28 ETS84192.1 - 2.4e-86 290.0 0.0 3.1e-86 289.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS84192.1 - 9.7e-15 55.3 2.1 3.2e-14 53.6 0.6 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ribosomal_S14 PF00253.21 ETS84194.1 - 6.6e-21 73.8 1.3 6.6e-21 73.8 1.3 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e TPR_12 PF13424.6 ETS84196.1 - 0.011 16.0 0.2 1.7 9.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4271 PF14093.6 ETS84197.1 - 0.041 13.8 6.8 0.18 11.7 2.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) DUF1772 PF08592.11 ETS84197.1 - 0.13 12.6 7.3 6.5 7.1 3.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Abhydrolase_9_N PF15420.6 ETS84197.1 - 0.22 11.5 6.3 0.26 11.3 0.5 2.5 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus zf-LITAF-like PF10601.9 ETS84197.1 - 0.33 11.3 0.1 0.33 11.3 0.1 3.3 3 1 1 4 4 4 0 LITAF-like zinc ribbon domain DUF2627 PF11118.8 ETS84198.1 - 0.02 15.4 1.6 0.14 12.7 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) DUF4271 PF14093.6 ETS84198.1 - 0.74 9.7 11.5 1.2 9.0 3.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) Glucan_synthase PF02364.15 ETS84198.1 - 1.5 6.9 7.0 1 7.5 0.1 2.2 2 1 0 2 2 2 0 1,3-beta-glucan synthase component TatC PF00902.18 ETS84198.1 - 2.6 7.8 11.1 0.79 9.5 7.0 2.2 1 1 1 2 2 2 0 Sec-independent protein translocase protein (TatC) DHHC PF01529.20 ETS84198.1 - 5.1 7.2 9.0 5.7 7.0 0.1 3.2 2 1 0 3 3 3 0 DHHC palmitoyltransferase APH PF01636.23 ETS84199.1 - 3.4e-18 66.5 0.0 1.2e-17 64.7 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETS84199.1 - 0.0092 15.6 0.2 0.018 14.6 0.2 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 ETS84199.1 - 0.1 12.2 0.0 12 5.4 0.0 2.3 2 0 0 2 2 2 0 RIO1 family MFS_1 PF07690.16 ETS84201.1 - 1.5e-31 109.6 35.0 1.5e-31 109.6 35.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS84201.1 - 1e-05 24.6 0.0 4.2e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 MFS_1 like family MFS_4 PF06779.14 ETS84201.1 - 1.1e-05 25.0 3.0 1.1e-05 25.0 3.0 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB A_deaminase PF00962.22 ETS84202.1 - 6.9e-37 127.5 0.0 8.2e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 ETS84202.1 - 0.0026 17.1 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Mpt_N PF09176.11 ETS84202.1 - 0.0055 16.8 0.5 0.12 12.5 0.1 2.3 2 0 0 2 2 2 1 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal DUF2764 PF10962.8 ETS84202.1 - 0.16 11.4 0.1 0.23 10.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) Phage_holin_3_6 PF07332.11 ETS84203.1 - 1.4 9.0 3.3 2.6 8.1 3.3 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III HAD_2 PF13419.6 ETS84204.1 - 1.7e-07 31.5 0.0 2.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETS84204.1 - 5.9e-06 26.7 0.0 1.9e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ETS84204.1 - 0.0015 18.6 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HNH PF01844.23 ETS84205.1 - 2.5e-05 24.3 0.5 6.9e-05 22.9 0.5 1.8 1 1 0 1 1 1 1 HNH endonuclease FYDLN_acid PF09538.10 ETS84205.1 - 0.078 13.7 1.4 0.15 12.7 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Ank_3 PF13606.6 ETS84206.1 - 1.1e-19 68.5 6.6 1.4e-06 28.1 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.7 ETS84206.1 - 1.9e-19 70.0 0.1 4e-08 33.7 0.0 4.2 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS84206.1 - 2.4e-18 66.2 1.1 9.3e-06 26.1 0.1 5.5 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 ETS84206.1 - 5.2e-16 58.3 11.5 9.6e-08 32.1 0.2 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 ETS84206.1 - 2e-14 53.5 5.0 6e-06 26.4 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeats (many copies) F-box-like PF12937.7 ETS84206.1 - 5e-05 23.1 0.1 8.9e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 F-box-like PCP_red PF08369.10 ETS84207.1 - 2.5 8.4 6.4 2.9 8.2 1.8 2.6 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit 4HBT_3 PF13622.6 ETS84209.1 - 4.3e-48 164.7 0.6 5e-48 164.5 0.6 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 ETS84209.1 - 1.2e-11 44.6 0.0 2.8e-08 33.7 0.0 2.9 2 1 1 3 3 3 2 Acyl-CoA thioesterase Cu-oxidase_3 PF07732.15 ETS84210.1 - 5.3e-40 136.1 2.6 5.3e-40 136.1 2.6 2.7 2 1 1 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ETS84210.1 - 2.1e-39 134.4 14.5 5.5e-38 129.8 0.8 4.1 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 ETS84210.1 - 1.5e-34 119.5 0.1 5.2e-34 117.7 0.1 1.9 2 0 0 2 2 2 1 Multicopper oxidase GP4 PF03010.14 ETS84210.1 - 0.13 12.2 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 GP4 Mito_carr PF00153.27 ETS84212.1 - 7.9e-54 179.6 2.7 3.1e-20 71.9 0.3 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF2370 PF10176.9 ETS84214.1 - 6.5e-94 313.8 0.0 9.3e-94 313.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Bac_chlorC PF02043.17 ETS84214.1 - 0.085 12.9 0.2 0.22 11.5 0.2 1.7 1 0 0 1 1 1 0 Bacteriochlorophyll C binding protein PCMT PF01135.19 ETS84215.1 - 1.7e-48 165.1 0.0 1.2e-15 57.8 0.0 3.0 3 0 0 3 3 3 3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ETS84215.1 - 8.7e-05 22.4 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ETS84215.1 - 0.001 19.1 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS84215.1 - 0.0038 17.9 0.0 0.0078 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS84215.1 - 0.017 15.0 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 ETS84215.1 - 0.023 15.4 0.0 0.04 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 ETS84215.1 - 0.068 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MTS PF05175.14 ETS84215.1 - 0.1 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain p450 PF00067.22 ETS84216.1 - 3.1e-51 174.6 0.0 4.1e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 ETS84217.1 - 7.1e-30 104.3 0.0 1.1e-29 103.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Iso_dh PF00180.20 ETS84219.1 - 1.3e-126 422.4 0.0 1.5e-126 422.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PHD PF00628.29 ETS84220.1 - 6.7e-08 32.3 6.2 1.2e-07 31.5 6.2 1.4 1 0 0 1 1 1 1 PHD-finger Glyco_hydro_92 PF07971.12 ETS84222.1 - 9.3e-140 466.6 4.4 1.1e-139 466.3 4.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 ETS84222.1 - 7.8e-52 176.5 4.1 1e-51 176.1 3.4 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain AFOR_N PF02730.15 ETS84222.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain Cu_amine_oxid PF01179.20 ETS84224.1 - 1.2e-157 525.0 0.0 1.5e-157 524.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 ETS84224.1 - 1.7e-08 34.6 1.4 2.1e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 ETS84224.1 - 8.5e-07 29.3 0.0 2.3e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Fungal_trans PF04082.18 ETS84225.1 - 2.2e-13 49.9 7.0 3.1e-13 49.4 7.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_9 PF13527.7 ETS84226.1 - 0.047 13.8 0.1 0.097 12.7 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Aldedh PF00171.22 ETS84227.1 - 1.7e-155 518.1 0.1 1.9e-155 517.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AA_permease PF00324.21 ETS84228.1 - 1.8e-121 406.0 42.3 2.3e-121 405.7 42.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS84228.1 - 8.4e-31 107.2 48.1 1.1e-30 106.8 48.1 1.2 1 0 0 1 1 1 1 Amino acid permease SnoaL_4 PF13577.6 ETS84229.1 - 3.4e-06 27.2 0.4 7.1e-06 26.2 0.4 1.5 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 ETS84229.1 - 3.4e-06 27.6 0.3 4.3e-06 27.3 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain Abhydrolase_1 PF00561.20 ETS84230.1 - 1.5e-44 152.6 0.0 9.3e-44 150.0 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 ETS84230.1 - 0.0024 17.6 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 ETS84230.1 - 0.011 15.5 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase zf-RING_6 PF14835.6 ETS84230.1 - 0.071 13.0 0.7 0.17 11.7 0.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein adh_short PF00106.25 ETS84231.1 - 7e-48 162.7 1.4 9e-48 162.3 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS84231.1 - 2.3e-43 148.5 1.5 2.9e-43 148.1 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS84231.1 - 5.5e-11 42.7 0.4 9e-11 42.0 0.4 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ETS84231.1 - 1.8e-05 24.7 0.1 2.6e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 ETS84231.1 - 4.7e-05 22.5 0.1 7.4e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ETS84231.1 - 0.00037 20.0 0.0 0.00052 19.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ETS84231.1 - 0.00058 19.4 0.1 0.001 18.6 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ETS84231.1 - 0.0062 15.7 0.0 0.0072 15.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ETS84231.1 - 0.013 15.0 0.6 0.06 12.9 0.5 2.0 3 0 0 3 3 3 0 NmrA-like family RmlD_sub_bind PF04321.17 ETS84231.1 - 0.048 12.7 0.1 0.076 12.1 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Ldh_1_N PF00056.23 ETS84231.1 - 0.064 13.4 0.3 0.16 12.1 0.3 1.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain p450 PF00067.22 ETS84232.1 - 2.1e-40 138.9 0.0 2.6e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-PARP PF00645.18 ETS84233.1 - 3.8e-24 85.4 1.1 1.1e-23 83.9 1.1 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Beta-lactamase PF00144.24 ETS84234.1 - 5.4e-24 85.0 0.0 1e-23 84.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase GGACT PF06094.12 ETS84235.1 - 7.7e-07 29.7 0.4 1.7e-06 28.6 0.4 1.5 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like EMC1_C PF07774.13 ETS84236.1 - 5.8e-74 248.4 0.0 1.4e-73 247.2 0.0 1.6 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 ETS84236.1 - 6.6e-23 81.5 7.2 1.5e-18 67.3 3.6 2.5 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 ETS84236.1 - 5.5e-07 29.2 0.7 0.0033 17.3 0.0 4.6 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_3 PF13570.6 ETS84236.1 - 0.076 13.5 0.1 13 6.4 0.0 3.8 3 0 0 3 3 3 0 PQQ-like domain DAO PF01266.24 ETS84237.1 - 4.6e-29 102.1 0.0 5.8e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS84237.1 - 5.8e-05 23.2 0.2 0.00019 21.6 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS84237.1 - 0.00018 20.9 0.0 0.026 13.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS84237.1 - 0.001 18.2 0.1 0.21 10.6 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Trp_halogenase PF04820.14 ETS84237.1 - 0.034 13.0 0.2 1.3 7.8 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.24 ETS84237.1 - 0.046 13.0 0.0 0.36 10.1 0.0 2.3 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 ETS84237.1 - 0.055 12.7 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.21 ETS84237.1 - 0.06 12.7 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 ThiF family NAD_binding_9 PF13454.6 ETS84237.1 - 0.067 13.2 0.3 4.8 7.1 0.0 2.9 3 1 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 ETS84237.1 - 0.11 13.1 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ETS84237.1 - 0.12 11.7 0.0 0.38 10.0 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 ETS84237.1 - 0.2 10.7 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Fungal_trans PF04082.18 ETS84238.1 - 9.8e-36 123.1 0.5 1.5e-35 122.5 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS84238.1 - 1.3e-09 38.0 7.4 2.7e-09 37.0 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sas10_Utp3 PF04000.15 ETS84241.1 - 1.3e-14 54.5 0.3 1.3e-14 54.5 0.3 2.3 2 1 0 2 2 2 1 Sas10/Utp3/C1D family DUF2052 PF09747.9 ETS84241.1 - 0.45 10.6 12.0 0.53 10.4 12.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PGA2 PF07543.12 ETS84241.1 - 0.87 9.6 16.1 1.5 8.8 16.1 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 SAPS PF04499.15 ETS84241.1 - 2.9 6.6 7.9 3.3 6.4 7.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF5093 PF17011.5 ETS84241.1 - 3.1 8.1 9.0 0.45 10.8 3.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5093) Hid1 PF12722.7 ETS84241.1 - 3.4 5.7 7.8 3.8 5.5 7.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM176 PF14851.6 ETS84241.1 - 4.2 7.0 7.9 6.4 6.4 7.9 1.2 1 0 0 1 1 1 0 FAM176 family DUF4598 PF15370.6 ETS84241.1 - 6.3 7.3 12.1 26 5.4 12.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4598) ApbA_C PF08546.11 ETS84242.1 - 1.9e-09 37.8 0.0 2.9e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 ETS84242.1 - 3.5e-05 23.5 0.0 5.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA dsDNA_bind PF01984.20 ETS84243.1 - 1.4e-40 138.0 10.5 1.7e-40 137.8 10.5 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Fes1 PF08609.10 ETS84243.1 - 0.0054 17.6 1.5 0.11 13.4 0.1 2.1 1 1 1 2 2 2 1 Nucleotide exchange factor Fes1 DUF4615 PF15393.6 ETS84243.1 - 0.019 15.5 1.0 0.026 15.1 0.6 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4615) Coq4 PF05019.13 ETS84244.1 - 6.7e-93 310.1 0.0 8.1e-93 309.8 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DUF2076 PF09849.9 ETS84245.1 - 6.2e-09 36.3 13.1 7.6e-09 36.0 13.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 ETS84245.1 - 0.00014 21.9 2.7 0.00014 21.9 2.7 1.5 2 0 0 2 2 2 1 CHCH domain GCK PF07802.11 ETS84245.1 - 0.001 19.5 0.1 0.0016 18.8 0.1 1.3 1 0 0 1 1 1 1 GCK domain Trypan_glycop_C PF10659.9 ETS84245.1 - 0.0073 16.7 1.7 0.012 15.9 1.7 1.3 1 0 0 1 1 1 1 Trypanosome variant surface glycoprotein C-terminal domain CX9C PF16860.5 ETS84245.1 - 0.48 10.5 3.9 0.58 10.2 2.4 1.8 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UBX PF00789.20 ETS84246.1 - 9.5e-14 51.4 0.0 2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 ETS84246.1 - 0.00049 20.2 1.7 0.0017 18.5 0.0 2.7 3 1 0 3 3 3 1 Thioredoxin-like Ank_2 PF12796.7 ETS84247.1 - 4e-55 184.3 9.2 2.3e-13 50.5 0.6 6.3 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS84247.1 - 3.5e-44 148.6 5.0 1.1e-08 35.4 0.0 9.2 3 2 7 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS84247.1 - 1.2e-42 143.4 6.2 4.3e-08 33.3 0.1 6.9 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 ETS84247.1 - 1.9e-42 141.9 14.2 2e-05 24.8 0.1 10.4 10 0 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.6 ETS84247.1 - 9.5e-34 111.6 7.5 8.4e-06 25.8 0.0 11.2 10 1 0 10 10 10 7 Ankyrin repeat AAA_16 PF13191.6 ETS84247.1 - 2.4e-06 28.1 0.0 8.4e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 ETS84247.1 - 4.4e-06 26.7 0.2 1e-05 25.5 0.2 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ETS84247.1 - 3.3e-05 24.2 1.1 0.00015 22.0 0.0 2.7 4 0 0 4 4 4 1 AAA domain KAP_NTPase PF07693.14 ETS84247.1 - 7.3e-05 22.2 3.2 0.001 18.4 0.2 3.0 3 0 0 3 3 3 1 KAP family P-loop domain AAA PF00004.29 ETS84247.1 - 0.00032 21.1 0.0 0.00071 20.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 ETS84247.1 - 0.021 14.0 0.0 0.042 13.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ATPase_2 PF01637.18 ETS84247.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 ETS84247.1 - 0.14 12.5 1.2 0.31 11.4 0.1 2.2 3 0 0 3 3 2 0 RNA helicase ABC_tran PF00005.27 ETS84247.1 - 0.17 12.4 0.1 1.1 9.8 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Cortex-I_coil PF09304.10 ETS84247.1 - 0.18 12.0 0.7 1.3 9.2 0.1 2.8 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF3445 PF11927.8 ETS84248.1 - 2.1e-71 240.1 0.1 2.5e-71 239.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) ADC PF06314.11 ETS84249.1 - 9.1e-33 113.8 0.0 1.1e-32 113.5 0.0 1.0 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) ADC PF06314.11 ETS84250.1 - 3.1e-23 82.6 0.0 4.2e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Fungal_trans_2 PF11951.8 ETS84251.1 - 3.2e-23 82.2 1.4 4.4e-23 81.7 1.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS84251.1 - 5.5e-09 36.0 9.4 1.2e-08 35.0 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EutQ PF06249.12 ETS84252.1 - 2.1e-08 34.1 0.0 2.6e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 ETS84252.1 - 1.6e-06 27.7 0.1 2.1e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 ETS84252.1 - 0.0017 18.0 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain KduI PF04962.12 ETS84252.1 - 0.13 11.6 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 KduI/IolB family Aldedh PF00171.22 ETS84253.1 - 8.8e-175 581.6 1.1 1e-174 581.5 1.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AA_permease_2 PF13520.6 ETS84254.1 - 8e-26 90.8 29.7 9.8e-26 90.5 29.7 1.1 1 0 0 1 1 1 1 Amino acid permease FAD_binding_4 PF01565.23 ETS84255.1 - 1.2e-18 67.2 3.6 2.3e-18 66.3 3.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS84255.1 - 0.00032 20.7 0.0 0.00077 19.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans_2 PF11951.8 ETS84256.1 - 3.6e-16 59.0 0.3 4.6e-16 58.6 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.26 ETS84257.1 - 5.2e-16 58.8 0.0 9.6e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS84257.1 - 4.6e-08 34.2 0.0 7.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS84257.1 - 4.6e-06 26.5 0.4 5.7e-05 23.0 0.3 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain HET PF06985.11 ETS84258.1 - 1.7e-29 103.0 0.0 2.9e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RRM_1 PF00076.22 ETS84259.1 - 7.4e-11 41.7 0.0 2e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 ETS84260.1 - 1.8e-54 183.7 0.0 2.1e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS84260.1 - 3.5e-21 75.6 0.0 5.1e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS84260.1 - 8e-08 31.9 0.0 9.6e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family CENP-T_C PF15511.6 ETS84261.1 - 2.3e-47 159.6 0.0 4.1e-47 158.8 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 ETS84261.1 - 5e-09 36.4 0.1 8.8e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 ETS84261.1 - 0.00025 21.4 2.0 0.00028 21.2 0.1 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ETS84261.1 - 0.00036 20.7 0.0 0.0011 19.2 0.0 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SURF1 PF02104.15 ETS84262.1 - 3.9e-45 154.3 0.2 6.6e-45 153.5 0.0 1.4 2 0 0 2 2 2 1 SURF1 family DUF3040 PF11239.8 ETS84262.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) CFEM PF05730.11 ETS84263.1 - 9e-07 28.9 5.8 1.6e-06 28.1 5.8 1.4 1 0 0 1 1 1 1 CFEM domain tRNA-synt_2 PF00152.20 ETS84264.1 - 3.6e-71 239.8 0.0 4.5e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ETS84264.1 - 1.1e-05 25.3 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain NARP1 PF12569.8 ETS84264.1 - 4.2 6.2 8.2 6.2 5.6 8.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CMS1 PF14617.6 ETS84265.1 - 3.1e-84 282.2 2.3 3.6e-84 282.0 2.3 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 ETS84265.1 - 1.1e-06 28.6 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ProQ_C PF17516.2 ETS84266.1 - 0.15 11.5 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 ProQ C-terminal domain Fumble PF03630.14 ETS84272.1 - 2.5e-148 493.7 0.2 3.1e-148 493.4 0.2 1.1 1 0 0 1 1 1 1 Fumble FCSD-flav_bind PF09242.11 ETS84272.1 - 0.13 12.6 0.1 0.38 11.1 0.1 1.8 1 0 0 1 1 1 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding RGS PF00615.19 ETS84273.1 - 3.9e-05 23.9 0.1 0.0055 17.0 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF1348 PF07080.11 ETS84274.1 - 3.3e-64 214.6 9.4 3.9e-64 214.4 9.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 ETS84274.1 - 3.4e-08 34.1 1.4 4.4e-08 33.7 1.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ETS84274.1 - 0.0002 21.7 0.2 0.00027 21.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 ETS84274.1 - 0.056 13.2 0.1 0.08 12.7 0.1 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Methyltransf_2 PF00891.18 ETS84275.1 - 4.8e-05 22.7 0.0 6.2e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_2 PF00891.18 ETS84276.1 - 2.2e-06 27.1 0.0 2.5e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 ETS84277.1 - 1.3e-06 28.3 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain AAA PF00004.29 ETS84278.1 - 4.1e-31 108.1 0.0 1.9e-30 106.0 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ETS84278.1 - 3.7e-06 26.7 0.1 1.1e-05 25.1 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 ETS84278.1 - 1.8e-05 24.5 0.0 4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ETS84278.1 - 0.00013 22.4 0.0 0.00065 20.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 ETS84278.1 - 0.00017 21.8 0.0 0.00067 19.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 ETS84278.1 - 0.0014 18.4 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 ETS84278.1 - 0.0026 18.0 0.1 0.076 13.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 ETS84278.1 - 0.0054 16.0 0.2 0.042 13.0 0.0 2.3 2 1 1 3 3 3 1 TIP49 P-loop domain AAA_5 PF07728.14 ETS84278.1 - 0.0085 16.1 0.0 0.03 14.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 ETS84278.1 - 0.023 14.4 0.1 0.062 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ETS84278.1 - 0.031 14.8 0.0 0.066 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.10 ETS84278.1 - 0.035 14.1 0.1 0.099 12.7 0.1 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain ABC_tran PF00005.27 ETS84278.1 - 0.04 14.4 0.1 0.25 11.9 0.0 2.3 3 0 0 3 3 3 0 ABC transporter AAA_14 PF13173.6 ETS84278.1 - 0.04 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ETS84278.1 - 0.056 12.8 0.3 0.2 11.0 0.2 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 ETS84278.1 - 0.064 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase IPT PF01745.16 ETS84278.1 - 0.15 11.4 0.8 0.68 9.3 0.1 2.2 2 0 0 2 2 2 0 Isopentenyl transferase REV1_C PF16727.5 ETS84278.1 - 0.15 12.4 0.6 0.34 11.3 0.6 1.5 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain Hydin_ADK PF17213.3 ETS84278.1 - 0.19 12.0 3.7 5.2 7.3 0.8 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_11 PF13086.6 ETS84278.1 - 0.34 10.7 1.3 0.6 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Clr5 PF14420.6 ETS84279.1 - 3.6e-10 39.9 5.9 3.6e-10 39.9 5.9 2.6 2 0 0 2 2 2 1 Clr5 domain TPR_12 PF13424.6 ETS84279.1 - 3e-09 37.0 12.4 0.0013 19.0 0.8 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 ETS84279.1 - 8.8e-05 22.4 3.6 0.0096 16.1 0.2 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 ETS84279.1 - 0.0014 18.4 1.8 0.7 9.8 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 ETS84279.1 - 0.0017 18.3 1.8 0.64 10.3 0.1 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat YfdX PF10938.8 ETS84279.1 - 0.0083 16.1 0.0 1 9.3 0.0 3.1 3 0 0 3 3 3 1 YfdX protein TPR_1 PF00515.28 ETS84279.1 - 0.01 15.7 1.4 2.3 8.2 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4404 PF14357.6 ETS84279.1 - 0.065 13.9 0.1 0.4 11.3 0.1 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) ANAPC3 PF12895.7 ETS84279.1 - 0.082 13.1 0.6 2.2 8.5 0.3 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ETS84279.1 - 0.23 11.6 5.0 13 6.1 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 ETS84279.1 - 5.6 8.1 5.8 24 6.1 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Oxidored_FMN PF00724.20 ETS84280.1 - 2e-34 119.4 0.0 2.6e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.16 ETS84281.1 - 8.3e-34 117.1 52.1 2.4e-33 115.5 52.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS84281.1 - 1.5e-07 30.6 13.6 1.5e-07 30.6 13.6 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter UBM PF14377.6 ETS84281.1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin binding region OATP PF03137.20 ETS84281.1 - 0.62 8.3 16.4 0.27 9.5 7.2 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.28 ETS84282.1 - 1.8e-52 178.4 0.0 2.6e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 ETS84282.1 - 2.8e-10 39.5 0.0 4.6e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 ETS84282.1 - 1e-07 32.2 0.5 3.6e-07 30.4 0.1 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ETS84282.1 - 0.00018 22.4 0.3 0.0016 19.4 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AATase PF07247.12 ETS84282.1 - 0.3 9.6 0.0 0.84 8.1 0.0 1.6 2 0 0 2 2 2 0 Alcohol acetyltransferase Abhydrolase_3 PF07859.13 ETS84283.1 - 1.9e-24 86.7 0.1 2.4e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS84283.1 - 2.7e-13 49.5 0.0 4.7e-12 45.4 0.0 2.0 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 ETS84283.1 - 0.022 14.2 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.28 ETS84283.1 - 0.19 10.6 0.2 0.92 8.3 0.0 2.0 3 0 0 3 3 3 0 Carboxylesterase family Zn_clus PF00172.18 ETS84284.1 - 8.9e-08 32.1 8.3 8.9e-08 32.1 8.3 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 ETS84285.1 - 9.9e-23 80.1 3.8 1.8e-22 79.3 3.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS84285.1 - 1.1e-17 64.2 0.0 1.9e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS84285.1 - 1.3e-06 29.4 0.0 2.4e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ETS84285.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 ETS84286.1 - 4.7e-11 43.2 0.0 1.3e-10 41.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS84286.1 - 4.2e-08 33.7 0.1 5.1e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS84286.1 - 2.4e-07 30.7 0.0 3.6e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 ETS84286.1 - 0.019 14.4 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_20 PF12147.8 ETS84286.1 - 0.16 11.1 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.18 ETS84286.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_19 PF04672.12 ETS84286.1 - 0.17 11.3 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase AMP-binding PF00501.28 ETS84287.1 - 1.5e-95 320.3 0.3 1.8e-95 320.1 0.3 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS84287.1 - 2.4e-10 41.3 0.0 6.2e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 ETS84288.1 - 6.4e-73 245.8 0.0 1e-72 245.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 ETS84288.1 - 1.8e-62 211.6 0.0 2.9e-31 108.7 0.0 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 ETS84288.1 - 1.1e-24 86.5 0.9 2.7e-11 43.6 0.2 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Podoplanin PF05808.11 ETS84289.1 - 0.0044 17.1 0.6 0.0063 16.6 0.6 1.2 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 ETS84289.1 - 0.034 13.6 0.7 0.071 12.5 0.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TPR_MalT PF17874.1 ETS84290.1 - 0.18 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 MalT-like TPR region Methyltransf_2 PF00891.18 ETS84291.1 - 1.1e-16 60.8 0.0 1.6e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 ETS84291.1 - 0.027 15.2 0.0 0.17 12.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain HTH_20 PF12840.7 ETS84291.1 - 0.043 13.9 0.3 0.17 12.0 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain CheR PF01739.18 ETS84291.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.12 ETS84291.1 - 0.14 13.0 0.0 0.97 10.2 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain HTH_24 PF13412.6 ETS84291.1 - 0.18 11.4 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding F-box-like PF12937.7 ETS84292.1 - 0.0001 22.1 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS84292.1 - 0.02 14.8 0.0 0.2 11.6 0.0 2.5 2 1 0 2 2 2 0 F-box domain HET PF06985.11 ETS84293.1 - 2.7e-29 102.4 0.3 4.9e-29 101.6 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) C1_2 PF03107.16 ETS84293.1 - 0.022 15.1 2.9 0.066 13.5 2.9 1.8 1 0 0 1 1 1 0 C1 domain CbiN PF02553.15 ETS84293.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Cobalt transport protein component CbiN Ank_2 PF12796.7 ETS84294.1 - 6e-39 132.5 1.2 1.5e-14 54.4 0.5 6.4 3 2 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS84294.1 - 5.4e-22 77.6 4.2 5.3e-07 29.8 0.4 6.1 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS84294.1 - 6e-21 72.3 7.6 0.071 13.7 0.1 11.5 11 1 1 12 12 10 4 Ankyrin repeat Ank_4 PF13637.6 ETS84294.1 - 1.8e-18 66.7 1.6 4.3e-05 24.0 0.0 6.2 5 1 3 8 8 6 4 Ankyrin repeats (many copies) NACHT PF05729.12 ETS84294.1 - 2.7e-11 43.7 0.0 6.4e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank PF00023.30 ETS84294.1 - 2.9e-11 43.3 12.3 0.023 15.1 0.1 9.5 11 1 0 11 11 9 3 Ankyrin repeat AAA_16 PF13191.6 ETS84294.1 - 3.1e-07 30.9 0.0 1.5e-06 28.7 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ETS84294.1 - 1.5e-05 25.4 0.0 9.1e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ETS84294.1 - 2.6e-05 23.9 0.0 6.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ETS84294.1 - 0.00057 20.2 0.0 0.0016 18.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ETS84294.1 - 0.00071 19.9 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Hydrolase_4 PF12146.8 ETS84294.1 - 0.0081 15.4 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 ETS84294.1 - 0.0095 15.5 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_24 PF13479.6 ETS84294.1 - 0.011 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ETS84294.1 - 0.015 15.8 0.0 0.051 14.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain RuvB_N PF05496.12 ETS84294.1 - 0.021 14.5 0.0 0.075 12.8 0.0 1.9 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ETS84294.1 - 0.032 14.2 0.0 0.37 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Abhydrolase_6 PF12697.7 ETS84294.1 - 0.045 14.3 0.3 0.16 12.6 0.3 2.0 1 0 0 1 1 1 0 Alpha/beta hydrolase family KAP_NTPase PF07693.14 ETS84294.1 - 0.059 12.6 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain DUF726 PF05277.12 ETS84294.1 - 0.13 11.2 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) LCAT PF02450.15 ETS84294.1 - 0.2 10.8 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase MMR_HSR1 PF01926.23 ETS84294.1 - 0.2 11.8 0.1 2.1 8.5 0.0 2.5 1 1 1 2 2 2 0 50S ribosome-binding GTPase Redoxin PF08534.10 ETS84295.1 - 1.7e-35 121.9 0.0 1.8e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ETS84295.1 - 1.8e-09 37.6 0.0 2.2e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1772 PF08592.11 ETS84296.1 - 1.7e-24 86.7 2.1 1.8e-24 86.6 1.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) ThiF PF00899.21 ETS84297.1 - 5.1e-41 140.6 0.0 8.7e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 ETS84297.1 - 0.00071 19.8 2.8 0.001 19.3 0.2 2.4 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ETS84297.1 - 0.0054 17.0 1.1 0.04 14.2 0.1 2.5 2 0 0 2 2 2 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 ETS84297.1 - 0.023 14.3 0.1 0.039 13.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 ETS84297.1 - 0.033 14.6 0.0 0.099 13.1 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding LapA_dom PF06305.11 ETS84297.1 - 0.17 11.7 0.0 0.46 10.3 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Peptidase_M14 PF00246.24 ETS84298.1 - 1.3e-46 159.7 0.6 1.6e-46 159.4 0.6 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase adh_short_C2 PF13561.6 ETS84299.1 - 3.3e-27 95.5 0.4 4.1e-27 95.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS84299.1 - 4.9e-20 71.8 0.1 8.6e-20 71.0 0.1 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ETS84299.1 - 0.0024 17.8 0.3 0.0041 17.1 0.3 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 ETS84299.1 - 0.0051 16.2 0.1 0.0089 15.4 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 ETS84299.1 - 0.009 16.4 0.1 0.016 15.7 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding NUDIX PF00293.28 ETS84300.1 - 3e-07 30.5 0.2 7.2e-07 29.3 0.2 1.7 1 1 0 1 1 1 1 NUDIX domain ABC_membrane PF00664.23 ETS84302.1 - 1e-87 294.3 48.7 1.5e-45 156.0 19.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ETS84302.1 - 2.6e-71 238.5 0.0 3.1e-34 118.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ETS84302.1 - 2.2e-13 50.1 0.0 0.00024 20.6 0.0 4.1 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ETS84302.1 - 1.3e-08 34.4 0.1 0.0027 17.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ETS84302.1 - 2.3e-07 31.4 2.3 0.00062 20.2 0.2 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 ETS84302.1 - 1.3e-06 28.7 0.3 0.072 13.4 0.0 3.9 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 ETS84302.1 - 1.4e-06 27.4 1.9 0.017 14.0 0.3 3.5 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 ETS84302.1 - 2.1e-06 27.7 0.0 0.039 13.6 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ETS84302.1 - 2.3e-06 27.6 0.0 0.077 12.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 ETS84302.1 - 2.7e-05 23.9 2.9 0.096 12.3 0.1 3.1 3 1 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 ETS84302.1 - 9.8e-05 21.7 0.1 0.29 10.4 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin AAA_30 PF13604.6 ETS84302.1 - 0.00013 21.7 1.6 0.49 10.1 0.1 3.8 4 0 0 4 4 4 2 AAA domain AAA_21 PF13304.6 ETS84302.1 - 0.00034 20.5 0.0 0.38 10.5 0.1 3.8 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ETS84302.1 - 0.0014 19.1 1.4 0.45 11.0 0.1 2.7 3 0 0 3 3 2 1 AAA domain G-alpha PF00503.20 ETS84302.1 - 0.0019 17.4 0.0 1.7 7.7 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_33 PF13671.6 ETS84302.1 - 0.002 18.3 0.1 1.9 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 ETS84302.1 - 0.0023 18.2 0.1 0.33 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ETS84302.1 - 0.0043 16.6 0.0 3.4 7.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 ETS84302.1 - 0.014 14.6 0.0 1.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 ETS84302.1 - 0.016 15.3 0.0 3.6 7.7 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 ETS84302.1 - 0.023 14.7 0.1 27 4.8 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 ETS84302.1 - 0.04 13.5 0.3 9.6 5.8 0.1 2.6 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA PF00004.29 ETS84302.1 - 0.074 13.5 3.3 23 5.4 0.0 4.4 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 ETS84302.1 - 0.076 13.6 0.1 19 5.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 ETS84302.1 - 0.1 12.5 0.0 6.3 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 ETS84302.1 - 0.12 12.8 0.0 7.1 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 ETS84302.1 - 0.13 11.4 0.1 9 5.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.25 ETS84302.1 - 0.41 10.3 1.6 58 3.2 0.1 3.4 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Aldedh PF00171.22 ETS84303.1 - 2.8e-136 454.7 0.0 3.4e-136 454.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ETS84303.1 - 0.0039 16.3 0.0 0.0091 15.1 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) ADH_zinc_N PF00107.26 ETS84304.1 - 5.1e-26 91.2 0.3 8.1e-26 90.5 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS84304.1 - 8.5e-21 73.9 1.1 8.5e-21 73.9 1.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ETS84304.1 - 0.00028 21.9 0.1 0.00047 21.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ETS84304.1 - 0.0013 18.0 3.2 0.0016 17.8 2.3 1.6 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SIS_2 PF13580.6 ETS84304.1 - 0.033 14.2 0.3 2.8 8.0 0.0 2.7 3 0 0 3 3 3 0 SIS domain 2-Hacid_dh_C PF02826.19 ETS84304.1 - 0.13 11.6 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Esterase_phd PF10503.9 ETS84305.1 - 7.5e-19 68.1 0.2 1.1e-18 67.5 0.2 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ETS84305.1 - 4.5e-13 49.2 0.6 6.4e-13 48.7 0.6 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 ETS84305.1 - 0.0001 21.3 0.7 0.00016 20.7 0.7 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS84305.1 - 0.0081 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.22 ETS84306.1 - 2.8e-65 220.9 0.0 3.8e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_lectin PF07938.12 ETS84307.1 - 2.4e-08 33.7 2.5 8.1e-06 25.4 1.0 2.2 2 0 0 2 2 2 2 Fungal fucose-specific lectin SKG6 PF08693.10 ETS84307.1 - 0.0018 17.7 0.1 0.0056 16.1 0.1 2.0 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.7 ETS84307.1 - 0.012 15.1 0.3 0.029 13.8 0.0 1.7 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Sugar_transport PF06800.12 ETS84307.1 - 0.1 11.9 0.4 0.17 11.2 0.4 1.3 1 0 0 1 1 1 0 Sugar transport protein PFK PF00365.20 ETS84308.1 - 5.2e-185 613.3 0.1 2.5e-104 348.6 0.6 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.19 ETS84308.1 - 0.019 14.7 1.3 0.052 13.3 1.3 1.7 1 0 0 1 1 1 0 UvrB/uvrC motif CBFD_NFYB_HMF PF00808.23 ETS84309.1 - 3.1e-17 62.6 0.3 3.1e-17 62.6 0.3 2.1 2 1 1 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ETS84309.1 - 1.1e-07 32.2 0.1 5.2e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 ETS84309.1 - 0.029 14.4 0.6 0.5 10.4 0.1 2.5 2 1 1 3 3 3 0 Bromodomain associated Spidroin_MaSp PF11260.8 ETS84309.1 - 0.043 14.1 0.1 0.099 12.9 0.1 1.6 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 Flu_M1_C PF08289.11 ETS84309.1 - 0.082 13.1 0.3 0.12 12.6 0.3 1.2 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain HEAT_PBS PF03130.16 ETS84309.1 - 0.11 13.2 0.0 8.8 7.3 0.0 2.5 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat RuvA_C PF07499.13 ETS84309.1 - 0.16 12.4 1.3 47 4.5 0.0 3.6 4 0 0 4 4 4 0 RuvA, C-terminal domain adh_short PF00106.25 ETS84310.1 - 9.2e-42 142.7 0.3 1.2e-41 142.4 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS84310.1 - 1.9e-33 115.9 0.2 2.3e-33 115.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS84310.1 - 1.4e-13 51.1 0.2 2e-13 50.6 0.2 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ETS84310.1 - 0.00065 19.6 0.2 0.00099 19.0 0.2 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS84310.1 - 0.011 15.3 0.1 0.13 11.8 0.1 2.0 2 0 0 2 2 2 0 NmrA-like family HEAT_2 PF13646.6 ETS84310.1 - 0.016 15.6 0.1 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 HEAT repeats Flot PF15975.5 ETS84310.1 - 0.022 14.9 0.0 0.069 13.3 0.0 1.7 2 0 0 2 2 2 0 Flotillin Epimerase PF01370.21 ETS84310.1 - 0.028 13.9 0.2 0.11 11.9 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ETS84310.1 - 0.038 13.1 0.1 0.047 12.8 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_Gly3P_dh_N PF01210.23 ETS84310.1 - 0.038 14.0 0.3 0.073 13.1 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF1776 PF08643.10 ETS84310.1 - 0.13 11.6 0.0 1 8.7 0.0 1.9 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) DAO PF01266.24 ETS84311.1 - 1.6e-43 149.7 3.2 1.9e-43 149.4 3.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS84311.1 - 0.00051 20.5 0.0 0.29 11.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS84311.1 - 0.0072 16.5 0.1 0.023 14.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 ETS84311.1 - 0.012 15.8 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain WT1 PF02165.15 ETS84311.1 - 0.018 14.3 0.1 0.027 13.7 0.1 1.2 1 0 0 1 1 1 0 Wilm's tumour protein Pyr_redox_2 PF07992.14 ETS84311.1 - 0.018 14.3 0.0 1.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS84311.1 - 0.038 13.1 0.0 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 ETS84311.1 - 0.14 12.1 0.1 0.35 10.8 0.0 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding COX16 PF14138.6 ETS84313.1 - 3.4e-33 114.0 0.1 4.4e-33 113.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 HTH_17 PF12728.7 ETS84313.1 - 0.053 13.7 0.1 0.088 13.0 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PI3_PI4_kinase PF00454.27 ETS84314.1 - 1.9e-49 168.7 0.0 3.9e-49 167.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 ETS84314.1 - 1.3e-37 129.9 9.7 2.9e-37 128.7 9.7 1.7 1 0 0 1 1 1 1 FAT domain UME PF08064.13 ETS84314.1 - 1.9e-22 79.1 1.0 2.4e-21 75.5 0.1 3.5 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.20 ETS84314.1 - 2.9e-15 55.8 0.0 6.9e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.6 ETS84314.1 - 0.00042 20.8 0.0 0.56 10.8 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 ETS84314.1 - 0.26 12.0 1.4 72 4.3 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat NUDIX PF00293.28 ETS84315.1 - 4.2e-16 59.2 0.1 7e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain DUF2721 PF11026.8 ETS84316.1 - 0.89 9.4 10.0 0.12 12.2 0.9 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2721) Popeye PF04831.13 ETS84316.1 - 4 7.6 6.9 2.5 8.3 2.9 2.2 2 0 0 2 2 2 0 Popeye protein conserved region FAD_binding_4 PF01565.23 ETS84317.1 - 3.4e-20 72.2 0.1 5.4e-20 71.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain KapB PF08810.10 ETS84317.1 - 0.076 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Kinase associated protein B FMN_dh PF01070.18 ETS84318.1 - 9e-110 367.0 0.0 1.1e-109 366.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ETS84318.1 - 2.4e-18 66.1 0.0 4.7e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 ETS84318.1 - 4.4e-05 22.8 0.0 7.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 ETS84318.1 - 0.0014 17.7 1.6 0.0049 15.9 0.8 2.1 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 ETS84318.1 - 0.0061 16.0 0.0 0.0093 15.4 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 ETS84318.1 - 0.12 11.6 0.1 0.75 8.9 0.1 2.0 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase HpcH_HpaI PF03328.14 ETS84319.1 - 5.8e-32 110.6 0.0 7.6e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 ETS84319.1 - 0.06 12.2 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain PEPcase_2 PF14010.6 ETS84319.1 - 0.15 10.5 0.0 0.27 9.7 0.0 1.3 1 1 0 1 1 1 0 Phosphoenolpyruvate carboxylase TauD PF02668.16 ETS84320.1 - 3e-52 178.1 0.3 3.5e-52 177.9 0.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Polyketide_cyc2 PF10604.9 ETS84321.1 - 0.0041 17.4 0.2 0.015 15.6 0.2 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF2236 PF09995.9 ETS84322.1 - 1.6e-27 97.2 0.3 2.7e-27 96.5 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) CD52 PF15116.6 ETS84322.1 - 0.042 13.9 0.3 0.075 13.1 0.3 1.4 1 0 0 1 1 1 0 CAMPATH-1 antigen DUF4044 PF13253.6 ETS84322.1 - 0.13 11.8 2.0 0.29 10.7 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) adh_short_C2 PF13561.6 ETS84323.1 - 3.6e-49 167.4 1.2 5.4e-49 166.9 1.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS84323.1 - 2e-47 161.2 0.3 3.1e-47 160.6 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS84323.1 - 3.4e-12 46.6 0.1 5.5e-12 46.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS84323.1 - 0.011 14.9 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 ETS84323.1 - 0.054 14.2 0.1 0.13 12.9 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.21 ETS84323.1 - 0.096 12.1 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 ETS84324.1 - 1.5e-09 37.3 0.1 2.8e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dioxygenase_C PF00775.21 ETS84325.1 - 5.6e-11 42.2 0.1 1e-10 41.4 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase SpaA PF17802.1 ETS84325.1 - 0.00091 19.5 2.3 0.0017 18.7 0.2 2.3 2 0 0 2 2 2 1 Prealbumin-like fold domain DUF1934 PF09148.10 ETS84325.1 - 0.11 12.6 0.5 0.17 11.9 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1934) FA_desaturase PF00487.24 ETS84326.1 - 4.1e-25 89.1 15.9 7.1e-25 88.3 15.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Abhydrolase_3 PF07859.13 ETS84327.1 - 1.7e-45 155.5 0.0 3.3e-45 154.5 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS84327.1 - 1.3e-08 34.1 0.2 5.6e-08 32.1 0.2 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 ETS84327.1 - 0.00086 20.0 0.1 0.0018 18.9 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ETS84327.1 - 0.0012 18.3 0.0 0.91 9.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 ETS84327.1 - 0.21 10.5 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme PS-DH PF14765.6 ETS84328.1 - 8.6e-65 218.9 0.1 1.3e-64 218.3 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 ETS84328.1 - 1.5e-60 204.9 0.0 3.8e-60 203.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 ETS84328.1 - 3.1e-60 204.4 1.6 4.8e-60 203.7 1.6 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 ETS84328.1 - 4.4e-60 202.7 0.0 1.1e-59 201.3 0.0 1.8 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 ETS84328.1 - 1.1e-33 115.8 0.2 3.1e-33 114.3 0.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ETS84328.1 - 1.8e-24 86.3 0.0 3.8e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 ETS84328.1 - 4.4e-15 56.2 0.0 1.7e-14 54.3 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS84328.1 - 5.3e-13 49.1 0.0 1.1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 ETS84328.1 - 7.4e-13 49.7 0.0 3e-12 47.7 0.0 2.1 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ETS84328.1 - 9e-13 48.3 0.4 3.7e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 ETS84328.1 - 4.4e-11 42.8 0.0 9.7e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS84328.1 - 3.3e-08 34.1 0.0 1.6e-07 32.0 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS84328.1 - 9.6e-08 32.6 0.0 2.9e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 ETS84328.1 - 1.4e-07 31.2 0.0 4.3e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase ADH_N PF08240.12 ETS84328.1 - 8.1e-05 22.5 0.0 0.00022 21.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 ETS84328.1 - 0.00021 21.6 0.0 0.00064 20.0 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 ETS84328.1 - 0.00042 20.0 0.0 0.0013 18.3 0.0 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_28 PF02636.17 ETS84328.1 - 0.0058 16.3 0.0 0.022 14.4 0.0 1.9 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MFS_1 PF07690.16 ETS84329.1 - 2.6e-28 99.0 36.1 2.6e-28 99.0 36.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS84329.1 - 6.8e-11 41.7 7.5 6.8e-11 41.7 7.5 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter BRI3BP PF14965.6 ETS84329.1 - 0.037 13.5 6.5 0.051 13.1 5.3 1.8 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Peptidase_M3 PF01432.20 ETS84330.1 - 1e-113 381.0 0.1 1.3e-113 380.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M32 PF02074.15 ETS84330.1 - 0.049 12.4 1.8 1.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase DUF3425 PF11905.8 ETS84331.1 - 1.1e-16 61.0 0.1 2.2e-13 50.3 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 ETS84331.1 - 0.0013 18.8 9.9 0.0015 18.6 8.9 1.5 1 1 1 2 2 2 1 bZIP transcription factor DUF2659 PF10858.8 ETS84331.1 - 0.097 12.3 0.2 0.16 11.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2659) putAbiC PF16872.5 ETS84331.1 - 0.15 12.7 0.1 0.27 11.9 0.1 1.3 1 0 0 1 1 1 0 Putative phage abortive infection protein FMO-like PF00743.19 ETS84332.1 - 9e-16 57.4 0.2 8e-14 50.9 0.1 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ETS84332.1 - 9e-10 38.3 0.0 7.6e-05 22.1 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS84332.1 - 5.1e-09 36.2 0.5 1.3e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ETS84332.1 - 2.7e-08 33.3 0.3 5.5e-06 25.8 0.0 3.2 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ETS84332.1 - 0.0014 18.3 0.1 1.6 8.2 0.0 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase Shikimate_DH PF01488.20 ETS84332.1 - 0.054 13.6 0.0 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 ETS84332.1 - 0.066 12.4 0.1 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Glycoamylase PF10091.9 ETS84332.1 - 0.078 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative glucoamylase Mqo PF06039.15 ETS84332.1 - 0.1 11.1 0.0 3.9 5.9 0.0 2.3 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Aldedh PF00171.22 ETS84333.1 - 1.1e-139 465.9 0.0 1.4e-139 465.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1189 PF06691.11 ETS84334.1 - 1.4 8.5 3.8 2.2 7.8 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Abhydrolase_3 PF07859.13 ETS84335.1 - 4.7e-50 170.4 0.0 6.2e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS84335.1 - 3e-14 52.7 0.0 4.1e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 ETS84335.1 - 0.00054 19.3 0.0 0.014 14.7 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS84335.1 - 0.0016 18.2 0.1 0.0025 17.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.12 ETS84335.1 - 0.0021 18.0 0.0 0.0047 16.9 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Abhydrolase_2 PF02230.16 ETS84335.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 ETS84335.1 - 0.094 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.18 ETS84335.1 - 0.11 12.1 0.0 19 4.7 0.0 2.6 2 1 0 2 2 2 0 Dienelactone hydrolase family MFS_1 PF07690.16 ETS84336.1 - 4.5e-27 94.9 31.9 6e-27 94.5 31.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS84336.1 - 0.0031 16.9 5.2 0.0031 16.9 5.2 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Rep_3 PF01051.21 ETS84337.1 - 0.006 16.4 0.0 0.0062 16.4 0.0 1.1 1 0 0 1 1 1 1 Initiator Replication protein GATase PF00117.28 ETS84338.1 - 4.9e-13 49.3 0.0 6.5e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ETS84338.1 - 5.4e-07 29.6 1.0 2.8e-06 27.2 0.7 2.2 2 1 0 2 2 2 1 Peptidase C26 Fungal_trans PF04082.18 ETS84339.1 - 2.3e-21 76.0 0.5 3.5e-21 75.4 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1155 PF06633.11 ETS84339.1 - 0.036 13.5 0.1 0.086 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1155) HET PF06985.11 ETS84340.1 - 1.5e-12 48.1 4.2 3.3e-09 37.3 0.3 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Arabinose_trans PF04602.12 ETS84340.1 - 0.12 11.1 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein Glyco_hydro_43 PF04616.14 ETS84341.1 - 0.0022 17.3 2.3 0.0022 17.3 2.3 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 HET PF06985.11 ETS84342.1 - 5.4e-35 120.9 1.0 5.4e-35 120.9 1.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TPR_12 PF13424.6 ETS84342.1 - 0.00022 21.4 0.0 0.00095 19.4 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 ETS84342.1 - 0.0016 18.3 0.0 0.063 13.3 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat RepL PF05732.11 ETS84342.1 - 0.009 15.5 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Firmicute plasmid replication protein (RepL) TPR_8 PF13181.6 ETS84342.1 - 0.048 13.9 0.0 0.24 11.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 ETS84342.1 - 0.16 11.9 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain MFS_1 PF07690.16 ETS84343.1 - 7.7e-22 77.7 28.6 1.2e-21 77.0 28.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1003 PF06210.11 ETS84343.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) FMN_dh PF01070.18 ETS84344.1 - 9.2e-119 396.5 0.1 1e-118 396.3 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ETS84344.1 - 7.7e-08 31.7 0.0 6.6e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ETS84344.1 - 4.9e-05 22.6 0.1 0.00012 21.4 0.0 1.6 1 1 1 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 ETS84344.1 - 0.00018 21.1 0.1 0.00034 20.1 0.1 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.21 ETS84344.1 - 0.0063 15.8 0.0 0.72 9.0 0.0 2.2 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase ThiG PF05690.14 ETS84344.1 - 0.026 13.9 0.1 4.8 6.4 0.0 2.6 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 ETS84344.1 - 0.12 11.8 0.0 0.75 9.2 0.0 2.1 1 1 0 2 2 2 0 Histidine biosynthesis protein Lactamase_B PF00753.27 ETS84345.1 - 2.5e-10 40.7 1.4 5.7e-10 39.5 1.4 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS84345.1 - 0.00046 19.8 0.0 0.0023 17.5 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ETS84345.1 - 0.0017 18.2 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain EpuA PF11772.8 ETS84345.1 - 0.29 10.9 3.4 7.3 6.4 0.1 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta adh_short_C2 PF13561.6 ETS84346.1 - 8.6e-59 198.9 2.5 1e-58 198.7 2.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS84346.1 - 2.2e-48 164.3 2.1 2.9e-48 163.9 2.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS84346.1 - 1e-08 35.3 0.2 1.9e-08 34.4 0.2 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS84346.1 - 0.059 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pyr_redox_3 PF13738.6 ETS84347.1 - 1.6e-17 63.7 0.1 5.6e-15 55.4 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS84347.1 - 3.7e-12 46.1 0.0 8.4e-09 35.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS84347.1 - 2.1e-09 37.5 3.6 0.00015 21.5 0.3 3.3 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS84347.1 - 6e-09 36.0 0.1 6e-09 36.0 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 ETS84347.1 - 2.4e-08 32.9 0.0 5.6e-07 28.4 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ETS84347.1 - 5.5e-06 25.8 0.0 0.0086 15.2 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 ETS84347.1 - 2.3e-05 23.7 0.1 3.8e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 ETS84347.1 - 3.8e-05 23.7 0.0 0.034 14.2 0.2 3.6 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ETS84347.1 - 0.001 18.4 0.8 0.012 14.8 1.0 2.2 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 ETS84347.1 - 0.0013 17.9 0.0 0.33 10.0 0.1 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 ETS84347.1 - 0.0017 17.5 0.0 0.041 12.9 0.0 2.9 3 1 0 3 3 3 1 Lycopene cyclase protein Shikimate_DH PF01488.20 ETS84347.1 - 0.018 15.1 0.0 3.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 ETS84347.1 - 0.063 12.0 1.1 0.23 10.1 0.6 2.2 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox PF00070.27 ETS84347.1 - 0.28 11.8 0.9 12 6.5 0.7 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 ETS84348.1 - 2.7e-53 180.9 0.3 3.8e-53 180.5 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS84348.1 - 4.2e-44 150.4 0.6 5.7e-44 149.9 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS84348.1 - 5.2e-12 46.0 2.6 3e-11 43.6 2.6 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS84348.1 - 0.0063 15.7 0.2 0.0095 15.1 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Dynamin_N PF00350.23 ETS84349.1 - 9.1e-36 123.4 0.4 1.8e-35 122.5 0.4 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 ETS84349.1 - 2.8e-22 79.3 0.0 4.1e-21 75.5 0.0 2.4 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 ETS84349.1 - 1.6e-06 28.2 1.0 1.9e-05 24.7 0.3 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 ETS84349.1 - 0.0097 16.1 0.0 0.057 13.6 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 ETS84349.1 - 0.065 12.8 0.5 16 5.0 0.0 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_21 PF13304.6 ETS84349.1 - 0.07 12.9 0.5 0.35 10.6 0.0 2.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system UDPG_MGDP_dh_N PF03721.14 ETS84349.1 - 0.15 11.6 0.1 0.4 10.2 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AAA_16 PF13191.6 ETS84349.1 - 0.24 11.8 3.2 1 9.7 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain Cyclase PF04199.13 ETS84351.1 - 2.1e-17 63.7 0.0 2.9e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase FMO-like PF00743.19 ETS84352.1 - 1.6e-15 56.6 0.1 6.3e-15 54.6 0.0 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ETS84352.1 - 4.3e-12 46.1 0.0 1.4e-11 44.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS84352.1 - 5.1e-06 25.9 0.0 0.0019 17.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS84352.1 - 6.7e-06 25.5 0.0 0.014 14.6 0.0 3.2 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ETS84352.1 - 3.6e-05 23.2 0.0 0.0004 19.7 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS84352.1 - 8.3e-05 22.6 0.0 0.0052 16.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 ETS84352.1 - 0.0016 18.1 0.0 0.029 14.0 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 ETS84352.1 - 0.0049 16.1 0.0 0.014 14.6 0.0 1.7 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 ETS84352.1 - 0.034 12.8 0.3 0.12 11.1 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 ETS84352.1 - 0.23 10.5 0.0 3 6.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A adh_short_C2 PF13561.6 ETS84353.1 - 2.5e-55 187.6 0.0 3.2e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS84353.1 - 5.6e-47 159.7 0.1 7.2e-47 159.4 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS84353.1 - 4e-06 26.8 0.1 7.2e-06 26.0 0.1 1.4 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 ETS84353.1 - 0.0012 17.9 1.2 0.0025 16.9 1.2 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 ETS84353.1 - 0.071 13.4 0.2 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.15 ETS84353.1 - 0.093 11.8 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 ETS84353.1 - 0.11 12.3 0.7 0.17 11.8 0.7 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_3 PF07859.13 ETS84354.1 - 1.3e-58 198.4 0.0 1.9e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS84354.1 - 1.1e-06 27.9 0.0 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 ETS84354.1 - 0.00065 20.4 0.4 0.00099 19.8 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ETS84354.1 - 0.0028 17.2 0.0 0.9 9.0 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 ETS84354.1 - 0.044 13.3 0.0 0.095 12.2 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Cyclase PF04199.13 ETS84355.1 - 4e-13 49.8 0.0 5.6e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase MTTB PF06253.11 ETS84355.1 - 0.017 13.1 0.1 0.023 12.7 0.1 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) UDPGT PF00201.18 ETS84356.1 - 0.00041 19.3 0.0 0.00069 18.5 0.0 1.3 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase SNF2_N PF00176.23 ETS84357.1 - 1.4e-66 224.6 0.1 2.3e-66 223.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS84357.1 - 9e-17 61.4 0.0 2.9e-16 59.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS84357.1 - 6.6e-08 32.7 0.0 1.8e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ETS84357.1 - 5.7e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Cwf_Cwc_15 PF04889.12 ETS84357.1 - 0.11 12.2 3.1 0.26 11.0 3.1 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TssN PF17555.2 ETS84357.1 - 0.26 10.7 0.5 0.4 10.0 0.5 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN CENP-B_dimeris PF09026.10 ETS84357.1 - 0.51 10.8 8.2 1.7 9.1 8.2 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3246 PF11596.8 ETS84357.1 - 1.4 8.3 6.9 4.7 6.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Tub_N PF16322.5 ETS84357.1 - 2 8.7 5.7 5.3 7.4 5.7 1.7 1 1 0 1 1 1 0 Tubby N-terminal Med17 PF10156.9 ETS84358.1 - 1.8e-89 300.6 0.0 2.3e-89 300.3 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex LigB PF02900.18 ETS84359.1 - 1.1e-40 139.5 0.0 1.2e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Abhydrolase_2 PF02230.16 ETS84360.1 - 3.4e-61 206.8 0.0 4.1e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ETS84360.1 - 1.6e-11 44.0 0.2 9.3e-06 25.1 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS84360.1 - 1.9e-08 34.3 0.1 0.012 15.2 0.1 3.0 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS84360.1 - 6.4e-08 32.3 0.2 6.8e-06 25.7 0.0 2.7 2 1 1 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.13 ETS84360.1 - 6.6e-07 29.2 0.0 0.00013 21.7 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 ETS84360.1 - 1.9e-05 24.3 0.0 3.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 ETS84360.1 - 9.5e-05 22.3 0.0 0.38 10.6 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS84360.1 - 0.00026 21.7 2.4 0.00055 20.6 1.7 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ETS84360.1 - 0.0042 16.9 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2920 PF11144.8 ETS84360.1 - 0.0076 15.5 0.0 0.59 9.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2920) Abhydrolase_4 PF08386.10 ETS84360.1 - 0.011 15.8 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Esterase_phd PF10503.9 ETS84360.1 - 0.024 14.1 0.1 0.71 9.3 0.0 2.2 1 1 1 2 2 2 0 Esterase PHB depolymerase BAAT_C PF08840.11 ETS84360.1 - 0.031 14.2 0.1 2 8.3 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 ETS84360.1 - 0.055 12.1 0.1 0.48 9.0 0.1 2.3 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) Esterase PF00756.20 ETS84360.1 - 0.2 11.2 0.2 0.47 10.1 0.2 1.9 1 1 0 1 1 1 0 Putative esterase LIP PF03583.14 ETS84360.1 - 0.22 10.8 0.0 5.9 6.1 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase DUF2974 PF11187.8 ETS84360.1 - 0.27 10.8 0.8 0.4 10.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Ank_2 PF12796.7 ETS84361.1 - 1.2e-31 109.1 7.4 3.1e-08 34.1 0.1 4.6 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS84361.1 - 5e-23 78.7 3.4 0.017 15.6 0.0 8.6 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 ETS84361.1 - 1.8e-19 69.5 8.5 0.00012 22.3 0.2 6.7 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS84361.1 - 5.9e-19 68.2 5.1 0.00068 20.1 0.4 5.4 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 ETS84361.1 - 7.4e-19 67.3 21.2 0.0071 16.7 0.1 8.9 9 0 0 9 9 9 7 Ankyrin repeat WD40 PF00400.32 ETS84362.1 - 9.4e-19 67.4 18.5 1.4e-05 25.7 0.4 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS84362.1 - 1.2e-05 25.6 0.0 0.0024 18.2 0.0 3.6 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 ETS84362.1 - 0.00026 19.7 2.8 0.096 11.2 0.1 3.7 4 0 0 4 4 4 2 Cytochrome D1 heme domain PD40 PF07676.12 ETS84362.1 - 0.012 15.5 0.2 0.13 12.2 0.0 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 ETS84362.1 - 0.22 10.8 0.8 1.1 8.5 0.0 2.4 3 0 0 3 3 3 0 WD40-like domain SecE PF00584.20 ETS84363.1 - 4.5e-14 52.1 0.0 5.1e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_1 PF00076.22 ETS84364.1 - 0.0028 17.5 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SnoaL_2 PF12680.7 ETS84365.1 - 0.006 17.2 0.1 0.0095 16.6 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like domain Abhydrolase_1 PF00561.20 ETS84366.1 - 5.7e-32 111.4 0.0 8.4e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS84366.1 - 2.9e-13 49.7 0.0 2.7e-12 46.5 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS84366.1 - 7.8e-09 36.4 0.1 1.2e-08 35.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ETS84366.1 - 0.00025 20.6 0.0 0.057 12.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family LIP PF03583.14 ETS84366.1 - 0.031 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase Ndr PF03096.14 ETS84366.1 - 0.082 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Ndr family Peptidase_S28 PF05577.12 ETS84366.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Sigma70_ner PF04546.13 ETS84367.1 - 0.0012 18.7 12.4 0.0017 18.3 12.4 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region SPATA24 PF15175.6 ETS84367.1 - 0.028 14.3 10.9 0.032 14.1 10.9 1.3 1 1 0 1 1 1 0 Spermatogenesis-associated protein 24 Fib_alpha PF08702.10 ETS84367.1 - 0.036 14.3 9.7 0.065 13.4 9.7 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 ETS84367.1 - 0.06 12.9 7.7 0.066 12.8 7.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HAUS6_N PF14661.6 ETS84367.1 - 0.062 12.9 7.5 0.078 12.5 7.5 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TMCO5 PF14992.6 ETS84367.1 - 0.068 12.7 10.8 0.088 12.4 10.8 1.1 1 0 0 1 1 1 0 TMCO5 family SH3BP5 PF05276.14 ETS84367.1 - 0.081 12.7 11.5 0.15 11.9 11.5 1.4 1 1 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) DUF4145 PF13643.6 ETS84367.1 - 0.083 13.0 0.9 0.15 12.2 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4145) Atg14 PF10186.9 ETS84367.1 - 0.14 11.2 10.5 0.2 10.7 10.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BST2 PF16716.5 ETS84367.1 - 0.75 10.4 11.0 0.66 10.6 8.7 2.1 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 Spt5_N PF11942.8 ETS84367.1 - 1.9 9.5 17.2 5 8.2 17.2 1.8 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF4407 PF14362.6 ETS84367.1 - 4.7 6.5 9.7 6.1 6.1 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LCIB_C_CA PF18599.1 ETS84367.1 - 9.8 5.4 8.0 1.9 7.7 1.8 2.0 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Fez1 PF06818.15 ETS84368.1 - 0.033 14.6 13.3 0.023 15.2 11.6 1.5 1 1 0 1 1 1 0 Fez1 Phage_TAC_3 PF06896.11 ETS84368.1 - 0.035 14.7 0.8 0.088 13.4 0.8 1.7 1 0 0 1 1 1 0 Phage tail assembly chaperone proteins, TAC DMPK_coil PF08826.10 ETS84368.1 - 0.046 13.8 0.9 0.046 13.8 0.9 2.2 3 0 0 3 3 3 0 DMPK coiled coil domain like PKcGMP_CC PF16808.5 ETS84368.1 - 0.059 13.2 1.7 0.095 12.6 0.1 2.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spt46 PF17734.1 ETS84368.1 - 0.18 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 DivIC PF04977.15 ETS84368.1 - 0.19 11.5 3.8 1 9.2 0.8 2.5 2 1 0 2 2 2 0 Septum formation initiator CENP-F_leu_zip PF10473.9 ETS84368.1 - 0.29 11.2 11.3 0.042 13.9 6.3 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APC_N_CC PF16689.5 ETS84368.1 - 0.72 10.0 4.6 5.4 7.2 0.7 3.1 3 1 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain OmpH PF03938.14 ETS84368.1 - 0.78 10.1 8.5 12 6.2 8.5 2.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 ETS84368.1 - 0.84 8.8 6.6 5.4 6.2 0.9 2.1 1 1 1 2 2 2 0 TMPIT-like protein Phage_GPO PF05929.11 ETS84368.1 - 0.87 9.1 6.4 0.24 11.0 3.0 1.7 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase 5_3_exonuc_N PF02739.16 ETS84368.1 - 0.93 9.4 3.9 7.4 6.5 3.8 2.1 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Sec2p PF06428.11 ETS84368.1 - 2 8.4 9.2 2.5 8.1 2.3 2.4 1 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Cnn_1N PF07989.11 ETS84368.1 - 2.3 8.5 12.9 0.13 12.4 1.9 3.0 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 TPR_MLP1_2 PF07926.12 ETS84368.1 - 2.6 8.1 13.1 0.44 10.6 3.7 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 ETS84368.1 - 3.2 8.0 9.5 0.21 11.8 1.4 2.5 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Sel1 PF08238.12 ETS84369.1 - 1.5e-44 149.4 22.6 1.6e-07 31.7 0.1 7.9 7 0 0 7 7 7 7 Sel1 repeat TPR_17 PF13431.6 ETS84369.1 - 0.021 15.2 0.0 1.8 9.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS84369.1 - 0.029 14.6 0.8 0.5 10.6 0.1 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 ETS84369.1 - 0.17 11.6 2.8 2 8.1 0.0 3.1 3 0 0 3 3 3 0 TPR repeat TPR_20 PF14561.6 ETS84369.1 - 0.17 12.2 1.3 0.4 11.1 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 ETS84369.1 - 3 8.4 9.3 33 5.1 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 ETS84369.1 - 3.1 8.8 8.2 3.9 8.6 0.1 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Ank_2 PF12796.7 ETS84370.1 - 9.6e-43 144.7 5.7 7.9e-12 45.6 0.1 5.9 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS84370.1 - 3.1e-32 110.5 8.8 1.6e-07 31.7 0.2 8.0 7 1 1 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS84370.1 - 1.5e-30 104.8 10.9 1.8e-07 31.3 0.0 8.0 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS84370.1 - 1.7e-30 101.7 7.1 0.0032 17.8 0.0 9.8 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 ETS84370.1 - 6.8e-26 89.5 15.7 0.00024 21.4 0.0 9.9 9 1 1 10 10 10 6 Ankyrin repeat NACHT PF05729.12 ETS84370.1 - 2.6e-14 53.5 0.0 5.8e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 ETS84370.1 - 3.8e-12 46.0 0.0 8.3e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.22 ETS84370.1 - 1.1e-05 24.8 0.1 2.2e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 ETS84370.1 - 0.0017 18.7 0.2 0.012 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 ETS84370.1 - 0.0047 17.4 0.0 0.027 14.9 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ETS84370.1 - 0.0062 16.7 0.0 0.026 14.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ETS84370.1 - 0.0088 15.6 0.0 0.036 13.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ETS84370.1 - 0.019 15.4 0.2 0.047 14.1 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_14 PF13173.6 ETS84370.1 - 0.029 14.4 0.0 0.36 10.9 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ETS84370.1 - 0.075 13.3 0.1 0.51 10.6 0.0 2.4 3 0 0 3 3 2 0 AAA domain Fungal_trans_2 PF11951.8 ETS84371.1 - 0.019 13.8 0.5 0.069 11.9 0.4 1.9 1 1 1 2 2 2 0 Fungal specific transcription factor domain LHC PF00556.20 ETS84371.1 - 0.15 12.3 2.7 15 5.8 0.0 2.4 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit RTA1 PF04479.13 ETS84372.1 - 2.9e-64 216.5 8.1 4.2e-64 216.0 8.1 1.2 1 0 0 1 1 1 1 RTA1 like protein Pex14_N PF04695.13 ETS84372.1 - 0.25 12.0 0.0 0.45 11.1 0.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Fungal_trans_2 PF11951.8 ETS84373.1 - 6.5e-48 163.5 5.6 6.5e-48 163.5 5.6 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Toxin_37 PF11415.8 ETS84373.1 - 0.089 12.6 0.2 0.38 10.6 0.2 2.1 1 0 0 1 1 1 0 Antifungal peptide termicin Zn_clus PF00172.18 ETS84373.1 - 0.11 12.7 1.0 0.24 11.6 1.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 ETS84374.1 - 7.8e-131 436.8 0.3 2.5e-130 435.1 0.3 1.6 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ETS84374.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF3445 PF11927.8 ETS84375.1 - 3e-75 252.7 0.0 3.4e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) AMP-binding PF00501.28 ETS84376.1 - 2.7e-41 141.6 0.0 3.7e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 ETS84376.1 - 1.8e-06 27.8 1.4 2.5e-05 24.1 0.2 2.5 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 ETS84376.1 - 0.007 17.3 0.1 0.085 13.8 0.0 2.7 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain FAD_binding_3 PF01494.19 ETS84377.1 - 1.3e-39 136.4 0.0 1.8e-24 86.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 ETS84377.1 - 2.6e-07 30.2 0.5 5e-05 22.7 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS84377.1 - 2.9e-06 26.7 0.1 0.0014 17.8 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 ETS84377.1 - 3.2e-06 26.6 0.0 6.4e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 ETS84377.1 - 5.1e-06 26.6 0.0 1.3e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS84377.1 - 0.00034 20.3 1.2 0.0044 16.6 0.1 2.8 2 1 1 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS84377.1 - 0.00044 19.6 0.1 0.0015 17.8 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS84377.1 - 0.00049 18.9 0.1 0.00093 18.0 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 ETS84377.1 - 0.0016 18.9 0.1 0.048 14.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ETS84377.1 - 0.0016 18.7 1.1 0.028 14.7 0.1 2.8 3 0 0 3 3 3 1 TrkA-N domain FAD_binding_2 PF00890.24 ETS84377.1 - 0.0022 17.2 0.1 0.0044 16.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ETS84377.1 - 0.011 14.8 0.1 0.018 14.1 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Mqo PF06039.15 ETS84377.1 - 0.026 13.1 0.1 4.1 5.8 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_oxidored PF12831.7 ETS84377.1 - 0.064 12.6 0.1 0.7 9.2 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS84377.1 - 0.093 12.7 0.2 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 ETS84377.1 - 0.21 10.6 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fungal_trans PF04082.18 ETS84378.1 - 0.00072 18.7 0.3 0.0014 17.7 0.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.18 ETS84379.1 - 3.1e-35 121.8 0.0 4.2e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyoxalase PF00903.25 ETS84380.1 - 3e-10 40.4 3.6 8.9e-10 38.9 1.9 2.1 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ETS84380.1 - 0.0017 18.6 0.1 0.0042 17.3 0.1 1.7 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Phyto_Pns9_10 PF05878.11 ETS84380.1 - 0.049 12.8 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 p450 PF00067.22 ETS84381.1 - 2.7e-68 230.8 0.0 3.6e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3939 PF13075.6 ETS84381.1 - 0.035 14.1 0.1 0.13 12.3 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) Glyco_hydro_71 PF03659.14 ETS84382.1 - 1.1e-136 455.6 5.5 1.1e-136 455.6 5.5 1.8 1 1 1 2 2 2 1 Glycosyl hydrolase family 71 DUF1180 PF06679.12 ETS84385.1 - 0.0054 17.2 0.2 0.0084 16.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) DUF2207 PF09972.9 ETS84385.1 - 0.0056 15.5 0.1 0.025 13.4 0.1 1.7 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) Rax2 PF12768.7 ETS84385.1 - 0.016 14.7 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.10 ETS84385.1 - 0.05 13.0 7.2 0.19 11.2 7.2 2.1 1 1 0 1 1 1 0 Transmembrane alpha-helix domain SSP160 PF06933.11 ETS84385.1 - 0.072 11.3 7.0 0.098 10.9 7.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DP PF08781.10 ETS84385.1 - 0.15 11.9 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Transcription factor DP p450 PF00067.22 ETS84386.1 - 1.6e-44 152.4 0.0 2e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 TPR_10 PF13374.6 ETS84387.1 - 6.7e-58 191.1 3.4 2.9e-08 33.3 0.3 8.2 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.6 ETS84387.1 - 2.1e-55 184.9 23.9 1.3e-11 44.6 0.1 6.5 1 1 7 8 8 8 8 Tetratricopeptide repeat TPR_8 PF13181.6 ETS84387.1 - 1.9e-15 55.7 0.2 0.051 13.8 0.1 6.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 ETS84387.1 - 2.2e-13 49.2 1.4 0.16 12.1 0.2 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 ETS84387.1 - 4.2e-11 42.7 3.4 1.6 9.7 0.0 7.0 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_4 PF07721.14 ETS84387.1 - 1e-10 41.2 6.6 0.61 10.9 0.0 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat Clr5 PF14420.6 ETS84387.1 - 3.6e-10 39.9 0.0 8.8e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Clr5 domain TPR_MalT PF17874.1 ETS84387.1 - 8.8e-10 38.5 21.1 3.9e-05 23.2 1.6 3.9 1 1 3 4 4 4 4 MalT-like TPR region TPR_1 PF00515.28 ETS84387.1 - 2.2e-09 36.7 2.5 0.14 12.0 0.1 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 ETS84387.1 - 1.2e-08 35.3 0.1 0.098 13.2 0.1 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 ETS84387.1 - 1.2e-07 31.2 9.4 0.15 12.2 0.2 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 ETS84387.1 - 2.8e-07 31.0 3.6 0.13 12.9 0.0 5.9 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 ETS84387.1 - 2.3e-06 27.9 7.2 0.28 11.9 0.0 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS84387.1 - 1.9e-05 24.8 3.2 0.15 12.3 0.0 4.8 2 2 3 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 ETS84387.1 - 0.14 12.2 0.1 19 5.3 0.0 3.8 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) TetR_C_20 PF17925.1 ETS84387.1 - 0.55 10.6 2.0 15 5.9 0.1 3.4 2 1 2 4 4 4 0 Tetracyclin repressor-like, C-terminal domain CBP4 PF07960.11 ETS84388.1 - 1.6e-29 102.4 0.4 2.2e-29 101.9 0.4 1.1 1 0 0 1 1 1 1 CBP4 Pkip-1 PF06878.11 ETS84388.1 - 0.054 13.6 0.4 0.066 13.3 0.4 1.1 1 0 0 1 1 1 0 Pkip-1 protein HisKA PF00512.25 ETS84388.1 - 0.077 13.1 0.6 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DUF4574 PF15141.6 ETS84388.1 - 0.097 12.6 0.0 0.39 10.7 0.0 1.8 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF2852 PF11014.8 ETS84388.1 - 0.12 12.5 0.6 0.12 12.5 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) SET PF00856.28 ETS84389.1 - 3.2e-14 53.7 0.0 4.5e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 SET domain Sugar_tr PF00083.24 ETS84390.1 - 5.7e-109 365.0 23.0 1.2e-108 363.9 23.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS84390.1 - 4.7e-25 88.2 82.0 7.4e-21 74.4 45.5 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily TPR_16 PF13432.6 ETS84390.1 - 0.018 15.7 0.1 0.037 14.7 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat MFS_2 PF13347.6 ETS84390.1 - 0.021 13.4 31.4 0.006 15.2 7.7 3.5 2 2 1 3 3 3 0 MFS/sugar transport protein HEAT_2 PF13646.6 ETS84391.1 - 0.043 14.2 0.0 0.28 11.6 0.0 2.5 1 0 0 1 1 1 0 HEAT repeats Nucleolin_bd PF16725.5 ETS84391.1 - 0.086 12.5 0.0 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 Nucleolin binding domain NusG PF02357.19 ETS84391.1 - 0.11 13.0 0.0 0.33 11.5 0.0 1.7 1 0 0 1 1 1 0 Transcription termination factor nusG OmdA PF13376.6 ETS84391.1 - 0.19 11.7 1.4 0.73 9.9 0.5 2.4 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated ABC_tran PF00005.27 ETS84392.1 - 1.9e-48 164.5 0.0 2.1e-25 89.8 0.0 4.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ETS84392.1 - 9.4e-14 51.9 3.9 0.00014 21.8 0.2 3.9 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETS84392.1 - 2.1e-13 50.2 0.0 8e-05 22.2 0.0 3.7 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ETS84392.1 - 8.8e-10 39.4 2.6 1.8e-05 25.3 0.1 3.1 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 ETS84392.1 - 2.7e-07 30.7 0.1 0.0026 17.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ETS84392.1 - 4.2e-07 30.0 0.0 0.006 16.7 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ETS84392.1 - 1.2e-06 28.2 0.6 0.023 14.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ETS84392.1 - 1.2e-05 25.6 0.1 0.16 12.2 0.0 3.3 2 1 0 2 2 2 2 AAA domain Chromo PF00385.24 ETS84392.1 - 0.00012 21.9 1.0 0.00024 20.9 1.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_15 PF13175.6 ETS84392.1 - 0.00024 20.9 0.2 0.42 10.3 0.2 2.7 2 1 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 ETS84392.1 - 0.0006 20.0 0.8 1.2 9.2 0.1 3.7 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_33 PF13671.6 ETS84392.1 - 0.0011 19.1 0.0 1.6 8.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ETS84392.1 - 0.0012 19.4 0.0 0.72 10.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 ETS84392.1 - 0.0014 18.9 0.0 0.11 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ETS84392.1 - 0.0014 19.0 0.1 2.1 8.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.23 ETS84392.1 - 0.0014 18.7 0.0 0.049 13.7 0.0 2.7 2 0 0 2 2 2 1 Dynamin family SbcCD_C PF13558.6 ETS84392.1 - 0.0025 18.0 0.0 1.8 8.9 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 ETS84392.1 - 0.0027 17.4 1.1 0.26 11.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ETS84392.1 - 0.0028 17.6 0.3 1.2 9.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain MeaB PF03308.16 ETS84392.1 - 0.0051 15.8 0.5 1.6 7.7 0.1 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 ETS84392.1 - 0.0052 16.5 0.0 0.38 10.5 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 ETS84392.1 - 0.0058 17.1 0.2 5.6 7.4 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS84392.1 - 0.012 16.0 0.2 1.9 8.9 0.0 3.5 3 0 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 ETS84392.1 - 0.013 15.8 0.0 3.9 7.7 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 ETS84392.1 - 0.016 14.9 0.4 6.6 6.4 0.1 2.9 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 ETS84392.1 - 0.017 14.7 0.7 7.5 6.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain SR-25 PF10500.9 ETS84392.1 - 0.019 14.6 2.4 0.035 13.7 2.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ALF PF03752.13 ETS84392.1 - 0.023 14.6 0.6 1.9 8.5 0.0 2.9 2 0 0 2 2 2 0 Short repeats of unknown function NB-ARC PF00931.22 ETS84392.1 - 0.026 13.7 0.0 1.6 7.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 ETS84392.1 - 0.027 13.6 0.0 3 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Septin PF00735.18 ETS84392.1 - 0.028 13.7 0.0 4.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Septin AAA_13 PF13166.6 ETS84392.1 - 0.053 12.2 0.0 3.4 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 ETS84392.1 - 0.057 12.9 0.5 1.5 8.2 0.0 2.7 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_14 PF13173.6 ETS84392.1 - 0.058 13.4 0.0 13 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ETS84392.1 - 0.077 12.9 0.4 25 4.7 0.3 3.0 3 0 0 3 3 3 0 NTPase Ploopntkinase3 PF18751.1 ETS84392.1 - 0.11 12.4 0.0 25 4.7 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 TsaE PF02367.17 ETS84392.1 - 0.13 12.3 0.9 23 5.0 0.1 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 ETS84392.1 - 0.15 11.5 0.1 16 4.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 ETS84392.1 - 0.18 11.4 0.8 14 5.3 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Fungal_trans_2 PF11951.8 ETS84393.1 - 0.0001 21.2 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 ETS84395.1 - 2e-34 119.1 15.7 2.9e-34 118.5 15.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS84395.1 - 1e-08 34.5 3.9 1e-08 34.5 3.9 1.8 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 ETS84395.1 - 6.2e-05 21.6 2.2 6.2e-05 21.6 2.2 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector TRI12 PF06609.13 ETS84395.1 - 0.034 12.6 1.6 0.053 11.9 1.6 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DoxD PF04173.13 ETS84395.1 - 0.089 12.7 1.3 0.2 11.6 1.3 1.5 1 0 0 1 1 1 0 TQO small subunit DoxD TMEM238 PF15125.6 ETS84395.1 - 1.4 9.2 9.6 3.5 7.9 0.3 3.1 3 0 0 3 3 3 0 TMEM238 protein family DUF3237 PF11578.8 ETS84396.1 - 5.1e-22 78.3 0.0 7e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Dmrt1 PF12374.8 ETS84397.1 - 1.3 9.5 9.1 1.8 9.0 4.1 2.3 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 MFS_1 PF07690.16 ETS84398.1 - 1.7e-26 93.0 37.1 1.7e-26 93.0 37.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FTA2 PF13095.6 ETS84399.1 - 7.3e-54 182.6 0.0 1.4e-53 181.7 0.0 1.5 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 ETS84399.1 - 0.059 12.7 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain MFAP1 PF06991.11 ETS84399.1 - 0.12 12.1 0.4 0.24 11.2 0.4 1.4 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing GLEYA PF10528.9 ETS84401.1 - 8.5e-21 74.2 3.8 8.5e-21 74.2 3.8 3.4 3 2 2 5 5 5 1 GLEYA domain Transp_cyt_pur PF02133.15 ETS84402.1 - 2e-92 310.3 36.9 2.6e-92 309.9 36.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.18 ETS84402.1 - 5.9e-21 74.7 1.2 1.1e-20 73.8 0.6 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS84402.1 - 0.0045 17.1 8.2 0.0088 16.2 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF917 PF06032.12 ETS84403.1 - 8e-115 383.4 0.1 2.4e-114 381.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 ETS84403.1 - 6.7e-29 100.8 1.6 7.5e-25 87.7 0.1 3.6 3 1 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 ETS84403.1 - 1.4e-21 77.1 17.3 5.8e-18 65.2 4.8 4.5 2 2 1 3 3 3 3 Hydantoinase/oxoprolinase MutL PF13941.6 ETS84403.1 - 1e-05 24.4 2.5 0.063 11.9 0.0 2.6 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 ETS84403.1 - 0.0044 16.6 10.9 0.044 13.3 0.6 2.5 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 ETS84403.1 - 0.0046 16.3 0.5 1.6 7.9 0.0 2.7 2 1 0 2 2 2 2 StbA protein ROK PF00480.20 ETS84403.1 - 0.0049 16.4 0.5 0.011 15.2 0.5 1.6 1 0 0 1 1 1 1 ROK family CM_1 PF07736.11 ETS84403.1 - 0.1 13.0 0.0 0.48 10.8 0.1 2.0 2 0 0 2 2 2 0 Chorismate mutase type I FtsA PF14450.6 ETS84403.1 - 0.21 12.0 5.3 2.4 8.7 0.5 3.3 3 1 1 4 4 4 0 Cell division protein FtsA DUF2786 PF10979.8 ETS84404.1 - 3.5e-11 42.8 0.1 3.5e-11 42.8 0.1 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2786) DUF3328 PF11807.8 ETS84405.1 - 1.8e-15 57.3 1.5 2.4e-14 53.6 1.5 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Cutinase PF01083.22 ETS84406.1 - 5.4e-34 117.7 8.0 1.1e-33 116.7 8.0 1.4 1 1 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 ETS84406.1 - 2.4e-05 24.2 0.3 3.4e-05 23.8 0.3 1.4 1 0 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.11 ETS84406.1 - 0.0036 16.9 0.2 0.0056 16.3 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.20 ETS84406.1 - 0.022 14.4 0.0 0.04 13.5 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 ETS84406.1 - 0.065 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 ETS84406.1 - 0.086 13.4 2.2 0.11 13.0 2.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 ETS84406.1 - 0.12 12.5 0.1 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain Tyrosinase PF00264.20 ETS84408.1 - 6.2e-31 108.4 6.4 1.5e-30 107.2 6.4 1.6 1 1 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.20 ETS84409.1 - 1.5e-18 67.9 8.4 5.2e-17 62.9 8.4 2.1 1 1 0 1 1 1 1 Common central domain of tyrosinase COesterase PF00135.28 ETS84410.1 - 5.6e-31 108.0 0.0 6.5e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 ETS84411.1 - 1.4e-50 172.7 0.0 1.8e-50 172.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 ETS84413.1 - 1.8e-96 324.1 0.0 2.3e-96 323.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS84413.1 - 6.3e-05 22.9 0.2 0.0052 16.7 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold TACC_C PF05010.14 ETS84414.1 - 0.17 11.7 36.9 0.17 11.6 11.4 3.6 1 1 3 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CENP-F_leu_zip PF10473.9 ETS84414.1 - 1.6 8.7 41.2 2.2 8.3 4.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF16 PF01519.16 ETS84414.1 - 2.6 8.6 33.5 0.78 10.3 6.2 3.6 2 1 2 4 4 4 0 Protein of unknown function DUF16 Spc7 PF08317.11 ETS84414.1 - 3.8 6.3 38.9 0.76 8.6 20.0 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein ATG16 PF08614.11 ETS84414.1 - 3.8 7.7 41.3 2.5 8.3 14.9 2.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 ETS84414.1 - 5.5 7.4 36.1 15 6.0 5.6 2.8 1 1 2 3 3 3 0 Fez1 TPR_MLP1_2 PF07926.12 ETS84414.1 - 7 6.7 43.9 0.28 11.3 5.7 3.7 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 ETS84415.1 - 0.0017 17.5 2.8 0.0024 17.0 2.8 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 FH2 PF02181.23 ETS84415.1 - 0.0063 15.7 0.9 0.0091 15.1 0.9 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain ZapB PF06005.12 ETS84415.1 - 0.034 14.6 6.0 0.92 10.0 0.1 2.6 1 1 1 2 2 2 0 Cell division protein ZapB TetR_C_15 PF17918.1 ETS84415.1 - 0.052 14.3 0.0 3.1 8.6 0.0 2.4 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF16 PF01519.16 ETS84415.1 - 0.072 13.6 4.1 0.12 12.9 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 UPF0242 PF06785.11 ETS84415.1 - 0.15 12.1 5.0 0.21 11.7 4.7 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 ETS84415.1 - 0.24 11.8 4.7 2.2 8.7 0.2 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TSC22 PF01166.18 ETS84415.1 - 8.4 6.8 7.2 9.3 6.7 0.2 2.7 1 1 1 3 3 3 0 TSC-22/dip/bun family Arylesterase PF01731.20 ETS84416.1 - 3.4e-05 24.0 0.2 0.00019 21.6 0.1 2.1 2 0 0 2 2 2 1 Arylesterase p450 PF00067.22 ETS84417.1 - 3.3e-58 197.6 0.0 6e-58 196.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 RAC_head PF16717.5 ETS84419.1 - 9.5e-31 106.7 2.6 9.5e-31 106.7 2.6 4.3 3 2 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 ETS84419.1 - 1.2e-18 66.9 0.7 1.2e-18 66.9 0.7 2.5 2 0 0 2 2 2 1 DnaJ domain Complex1_LYR PF05347.15 ETS84420.1 - 2.7e-05 24.1 0.0 4.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ETS84420.1 - 0.0036 18.0 0.1 0.0044 17.8 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like FAD_binding_3 PF01494.19 ETS84422.1 - 6.5e-21 75.0 0.0 5.9e-12 45.5 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 ETS84422.1 - 0.0003 20.5 0.1 0.00098 18.8 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ETS84422.1 - 0.00044 19.4 0.9 0.024 13.7 0.2 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ETS84422.1 - 0.00068 19.0 0.0 0.0031 16.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS84422.1 - 0.00099 18.4 0.3 0.018 14.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS84422.1 - 0.001 19.3 0.2 0.0074 16.5 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ETS84422.1 - 0.004 17.7 0.4 0.0098 16.4 0.4 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS84422.1 - 0.013 14.8 0.1 0.027 13.7 0.1 1.5 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 ETS84422.1 - 0.067 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 ETS84422.1 - 0.079 12.0 0.3 0.14 11.2 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain DUF3775 PF12616.8 ETS84422.1 - 0.11 12.6 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) DUF3425 PF11905.8 ETS84423.1 - 9e-23 80.6 0.0 1.4e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 ETS84423.1 - 0.76 9.9 10.5 1.2 9.2 10.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor FMO-like PF00743.19 ETS84424.1 - 8e-15 54.2 0.8 2.1e-12 46.3 0.9 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ETS84424.1 - 6.7e-10 39.1 0.0 5.3e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS84424.1 - 6.7e-06 25.5 0.0 0.028 13.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS84424.1 - 0.00011 21.4 0.1 0.0049 16.0 0.1 3.0 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ETS84424.1 - 0.0018 17.6 0.4 0.49 9.6 0.3 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS84424.1 - 0.0051 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family RsbRD_N PF14361.6 ETS84424.1 - 0.068 13.9 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain Shikimate_DH PF01488.20 ETS84424.1 - 0.075 13.1 0.0 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 ETS84424.1 - 0.084 12.9 0.0 0.66 9.9 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Acetyltransf_2 PF00797.17 ETS84425.1 - 1.8e-22 80.3 0.0 2.5e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase RRM_1 PF00076.22 ETS84426.1 - 1.2e-09 37.8 0.0 2.4e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ETS84426.1 - 0.0015 18.4 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 ETS84426.1 - 0.0032 17.4 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 ETS84426.1 - 0.0039 17.2 0.0 0.0089 16.1 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif AMP-binding PF00501.28 ETS84427.1 - 4.3e-79 266.1 0.0 5.3e-79 265.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS84427.1 - 4e-15 56.5 0.0 8.8e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 ETS84428.1 - 1.8e-30 106.1 33.7 1.8e-30 106.1 33.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily NnrU PF07298.11 ETS84428.1 - 0.096 12.2 0.0 0.096 12.2 0.0 3.8 4 1 0 4 4 4 0 NnrU protein HET PF06985.11 ETS84429.1 - 6.8e-11 42.7 4.3 6.6e-08 33.0 0.6 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Acetyltransf_3 PF13302.7 ETS84430.1 - 6.9e-14 52.7 0.0 1.5e-13 51.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS84430.1 - 0.0015 18.8 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 ETS84430.1 - 0.0021 18.2 0.0 0.0041 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ETS84430.1 - 0.0059 16.3 0.1 0.01 15.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FAA_hydrolase PF01557.18 ETS84431.1 - 3.6e-58 196.8 0.0 4.2e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Lactonase PF10282.9 ETS84432.1 - 7.2e-69 232.6 0.5 1.5e-68 231.6 0.2 1.6 1 1 1 2 2 2 1 Lactonase, 7-bladed beta-propeller MFS_1 PF07690.16 ETS84433.1 - 8.4e-21 74.3 55.1 8.4e-21 74.3 55.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 ETS84433.1 - 0.002 16.8 14.4 0.002 16.8 14.4 2.3 1 1 0 2 2 2 1 Vacuole effluxer Atg22 like Aldolase_II PF00596.21 ETS84434.1 - 1.6e-47 161.8 0.5 2e-47 161.5 0.5 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PhyH PF05721.13 ETS84435.1 - 2.3e-05 24.7 0.1 3.9e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1932 PF09130.11 ETS84436.1 - 2.6e-19 68.9 0.1 1.1e-18 67.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 ETS84436.1 - 3.4e-05 24.1 0.0 6.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ETS84436.1 - 0.00032 21.2 0.0 0.00071 20.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ETS84436.1 - 0.002 17.5 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ETS84436.1 - 0.04 14.0 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 ETS84436.1 - 0.058 13.3 0.1 0.089 12.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 ETS84436.1 - 0.19 11.6 1.0 0.26 11.1 0.1 1.7 2 0 0 2 2 2 0 Rossmann-like domain DUF2100 PF09873.9 ETS84436.1 - 0.21 11.4 0.0 0.34 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) Cu-oxidase PF00394.22 ETS84437.1 - 1.5e-21 77.2 0.1 4e-21 75.8 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ETS84437.1 - 2e-20 72.9 10.7 9.3e-19 67.5 5.1 3.8 2 2 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 ETS84437.1 - 1.2e-17 64.1 4.9 4.2e-16 59.0 0.6 3.3 2 1 0 2 2 2 1 Multicopper oxidase RraA-like PF03737.15 ETS84438.1 - 1.5e-23 83.6 0.0 2.1e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Aldolase/RraA Sugar_tr PF00083.24 ETS84439.1 - 1.1e-100 337.7 18.4 1.3e-100 337.5 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS84439.1 - 3.3e-27 95.4 20.5 3.3e-27 95.4 20.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DIOX_N PF14226.6 ETS84440.1 - 1.1e-22 80.9 0.0 1.8e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS84440.1 - 5.6e-15 55.7 0.0 1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 ETS84441.1 - 6.9e-46 156.8 34.8 8.2e-46 156.5 34.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS84441.1 - 6.6e-09 35.1 14.5 2.3e-08 33.3 14.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 ETS84441.1 - 5.2e-06 25.0 8.3 0.00037 18.9 9.7 2.3 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 ETS84441.1 - 7.6e-05 21.3 4.8 0.00013 20.5 4.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 ETS84441.1 - 0.001 18.5 11.2 0.001 18.5 11.2 2.5 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB Pam17 PF08566.10 ETS84441.1 - 0.56 10.0 3.6 2 8.3 0.2 2.9 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 DUF1129 PF06570.11 ETS84441.1 - 1.7 8.1 5.1 1.3 8.4 3.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Tyrosinase PF00264.20 ETS84442.1 - 2.3e-48 165.4 1.7 2.9e-48 165.1 1.7 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Fungal_trans PF04082.18 ETS84443.1 - 1e-07 31.2 0.1 2e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 ETS84445.1 - 9e-09 35.2 0.1 1.2e-08 34.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS84445.1 - 1.1e-08 34.8 0.2 1.6e-08 34.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 ETS84445.1 - 1.8e-06 27.7 1.1 3.3e-06 26.8 1.1 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS84445.1 - 0.00016 21.7 0.5 0.0003 20.7 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 ETS84445.1 - 0.00093 19.1 0.1 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 ETS84445.1 - 0.059 13.8 0.2 0.17 12.4 0.1 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 ETS84446.1 - 1.6e-08 33.8 1.8 2.3e-08 33.3 1.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 ETS84447.1 - 1.5e-45 155.8 0.0 2e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 ETS84448.1 - 1e-44 152.9 35.5 1e-44 152.9 35.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS84448.1 - 5.9e-08 32.0 14.6 5.9e-08 32.0 14.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 ETS84448.1 - 3.1e-05 22.6 0.3 5.9e-05 21.7 0.3 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector DUF4191 PF13829.6 ETS84448.1 - 9.2 5.5 9.6 0.36 10.1 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4191) Fungal_trans_2 PF11951.8 ETS84449.1 - 2.2e-12 46.5 3.0 5.7e-08 32.0 0.3 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS84449.1 - 1.9e-08 34.3 5.2 4.2e-08 33.2 5.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIID_NTD2 PF04494.15 ETS84449.1 - 0.0029 17.8 0.1 0.0064 16.7 0.1 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain MFS_1 PF07690.16 ETS84450.1 - 1.9e-26 92.9 24.0 1.9e-26 92.9 24.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS84450.1 - 1.9e-07 30.4 11.8 1.9e-07 30.4 11.8 3.0 2 2 0 2 2 2 1 Sugar (and other) transporter PTR2 PF00854.21 ETS84450.1 - 0.00037 19.4 0.6 0.00037 19.4 0.6 1.8 2 0 0 2 2 2 1 POT family DAO PF01266.24 ETS84451.1 - 4.9e-40 138.2 1.6 5.8e-40 138.0 1.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS84451.1 - 4e-06 27.0 0.5 1.4e-05 25.2 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS84451.1 - 2.9e-05 24.1 0.0 0.0017 18.4 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 ETS84451.1 - 0.00011 21.5 1.1 0.00044 19.6 0.2 2.1 1 1 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 ETS84451.1 - 0.00042 19.6 0.5 0.0013 18.0 0.4 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 ETS84451.1 - 0.0015 17.4 0.1 0.0021 17.0 0.1 1.3 1 0 0 1 1 1 1 MCRA family Pyr_redox_3 PF13738.6 ETS84451.1 - 0.0094 15.2 0.0 2.8 7.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS84451.1 - 0.02 15.5 0.1 0.053 14.1 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS84451.1 - 0.025 13.7 1.5 0.057 12.5 0.7 1.9 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 ETS84451.1 - 0.034 13.2 0.1 0.053 12.6 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.24 ETS84451.1 - 0.21 10.8 2.6 2.2 7.5 0.1 3.0 2 1 0 3 3 3 0 Flavin containing amine oxidoreductase COesterase PF00135.28 ETS84452.1 - 3.5e-67 227.4 0.0 4.3e-67 227.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS84452.1 - 1.4e-05 25.1 0.3 0.15 11.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 ETS84452.1 - 0.0011 18.7 0.1 0.0068 16.1 0.0 2.0 2 0 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.21 ETS84452.1 - 0.0055 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Acetyltransf_7 PF13508.7 ETS84453.1 - 5.2e-09 36.4 0.0 1e-08 35.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS84453.1 - 7.4e-09 35.9 0.0 1.1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS84453.1 - 1.8e-07 31.1 0.0 2.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETS84453.1 - 0.032 14.3 0.1 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF3237 PF11578.8 ETS84454.1 - 7.2e-27 94.1 0.1 8.3e-27 93.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Methyltransf_11 PF08241.12 ETS84455.1 - 2.7e-14 53.6 0.1 5.8e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS84455.1 - 4.3e-13 49.3 0.2 1.5e-11 44.3 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS84455.1 - 8.3e-13 48.9 0.1 1.7e-12 47.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS84455.1 - 1.3e-09 37.8 0.0 2.1e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ETS84455.1 - 1e-08 35.8 0.1 3.7e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS84455.1 - 5.9e-07 29.5 0.0 9.5e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ETS84455.1 - 0.00033 20.7 0.0 0.0005 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 ETS84455.1 - 0.025 14.7 0.2 0.044 13.9 0.2 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 ETS84455.1 - 0.027 14.0 0.1 0.049 13.2 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Amidohydro_2 PF04909.14 ETS84455.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.3 1 1 0 1 1 1 0 Amidohydrolase AAA_12 PF13087.6 ETS84456.1 - 2.7e-33 115.3 0.0 5.4e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ETS84456.1 - 1.1e-24 87.7 5.3 4.7e-13 49.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 ETS84456.1 - 5.2e-09 36.6 0.0 0.00017 22.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 ETS84456.1 - 1.5e-07 31.3 0.0 6.1e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 ETS84456.1 - 0.0067 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 ETS84456.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein CDH-cyt PF16010.5 ETS84457.1 - 1.5e-55 187.7 3.0 1.5e-55 187.7 3.0 2.3 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 ETS84457.1 - 6.3e-26 91.4 0.0 1e-25 90.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS84457.1 - 2.1e-18 67.2 0.5 4.6e-18 66.1 0.5 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS84457.1 - 1.7e-05 24.1 1.6 5.5e-05 22.4 1.6 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS84457.1 - 0.00023 20.5 0.1 0.003 16.9 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS84457.1 - 0.00023 20.5 0.7 0.00036 19.9 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS84457.1 - 0.00027 20.6 0.5 0.0023 17.6 0.2 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS84457.1 - 0.00033 19.5 0.8 0.0012 17.7 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 ETS84457.1 - 0.0014 17.9 0.7 0.037 13.3 1.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS84457.1 - 0.003 16.7 0.1 0.0059 15.7 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ETS84457.1 - 0.0059 16.8 0.3 0.0059 16.8 0.3 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ETS84457.1 - 0.0086 15.5 0.7 0.016 14.6 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ETS84457.1 - 0.022 14.0 0.2 0.059 12.6 0.3 1.6 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 ETS84457.1 - 0.075 12.7 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TPR_12 PF13424.6 ETS84458.1 - 1.1e-53 179.4 26.9 4.4e-17 62.1 0.3 5.1 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 ETS84458.1 - 1.3e-51 171.1 16.1 3.9e-11 42.4 0.1 8.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.28 ETS84458.1 - 4.2e-12 45.3 3.9 0.28 11.1 0.1 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat NB-ARC PF00931.22 ETS84458.1 - 4.8e-12 45.6 0.0 1.4e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain HET PF06985.11 ETS84458.1 - 8.9e-12 45.6 5.4 8.7e-10 39.1 0.6 2.9 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_7 PF13176.6 ETS84458.1 - 2.8e-11 42.6 19.4 0.053 13.6 0.0 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 ETS84458.1 - 4.2e-10 39.0 7.4 0.1 12.8 0.1 7.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS84458.1 - 3.4e-09 36.5 6.7 0.0002 20.8 0.6 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 ETS84458.1 - 1.7e-08 33.9 12.1 0.92 9.8 0.1 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 ETS84458.1 - 2.8e-07 30.5 6.3 0.31 11.8 0.5 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 ETS84458.1 - 6.4e-06 26.2 3.7 10 6.8 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS84458.1 - 6.6e-06 26.3 1.1 0.86 9.9 0.0 4.1 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 AAA_16 PF13191.6 ETS84458.1 - 4.7e-05 23.8 1.7 0.00014 22.3 0.2 2.6 2 1 0 2 2 1 1 AAA ATPase domain Coatomer_E PF04733.14 ETS84458.1 - 0.00032 20.2 1.2 0.59 9.5 0.1 3.3 1 1 2 3 3 3 2 Coatomer epsilon subunit NACHT PF05729.12 ETS84458.1 - 0.0012 18.8 0.0 0.0026 17.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_14 PF13428.6 ETS84458.1 - 0.002 18.8 14.8 8.7 7.5 0.1 7.9 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 ETS84458.1 - 0.002 18.6 11.7 8.1 7.0 0.3 5.8 3 1 5 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 ETS84458.1 - 0.0059 17.2 5.7 1.3e+02 3.5 0.0 6.5 6 0 0 6 6 5 0 Tetratricopeptide repeat AAA_22 PF13401.6 ETS84458.1 - 0.0099 16.2 0.0 0.072 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Wzy_C_2 PF11846.8 ETS84458.1 - 0.017 15.0 2.3 11 5.9 0.1 4.5 5 0 0 5 5 5 0 Virulence factor membrane-bound polymerase, C-terminal TPR_16 PF13432.6 ETS84458.1 - 0.024 15.3 3.9 61 4.4 0.0 5.2 4 2 1 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 ETS84458.1 - 0.046 14.0 5.2 80 3.8 0.0 5.5 6 0 0 6 6 5 0 PPR repeat Fig1 PF12351.8 ETS84462.1 - 1.9e-10 41.0 0.5 6.3e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 ABC2_membrane PF01061.24 ETS84462.1 - 0.088 12.2 8.8 0.11 11.9 4.9 2.1 2 0 0 2 2 2 0 ABC-2 type transporter Macoilin PF09726.9 ETS84463.1 - 1.6 7.2 8.1 1.8 7.0 8.1 1.1 1 0 0 1 1 1 0 Macoilin family PBP1_TM PF14812.6 ETS84463.1 - 3.8 8.0 11.4 1.9 8.9 5.5 2.9 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_17 PF00332.18 ETS84464.1 - 2.6e-10 40.4 0.4 2.3e-05 24.2 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF2140 PF09911.9 ETS84464.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) PTPLA PF04387.14 ETS84466.1 - 4e-46 156.8 0.3 6.9e-46 156.0 0.3 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA FAD_binding_4 PF01565.23 ETS84467.1 - 8e-26 90.4 1.3 1e-25 90.1 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain DUF2491 PF10679.9 ETS84467.1 - 0.016 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) Lactamase_B PF00753.27 ETS84468.1 - 5.3e-10 39.6 0.2 9.8e-10 38.8 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS84468.1 - 0.0088 15.6 0.1 0.026 14.1 0.1 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ORC6 PF05460.13 ETS84469.1 - 0.1 11.9 0.5 0.11 11.7 0.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF2582 PF10771.9 ETS84469.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix domain (DUF2582) Med3 PF11593.8 ETS84469.1 - 1.4 8.0 8.3 1.7 7.8 8.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FYDLN_acid PF09538.10 ETS84469.1 - 2 9.1 11.4 4.3 8.1 11.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) NAP PF00956.18 ETS84470.1 - 1.5e-27 96.4 0.0 2.7e-27 95.6 0.1 1.3 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Scytalone_dh PF02982.14 ETS84473.1 - 4.9e-91 302.7 0.4 5.8e-91 302.5 0.4 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 ETS84473.1 - 5.3e-08 33.0 0.5 8.6e-08 32.4 0.5 1.3 1 0 0 1 1 1 1 SnoaL-like domain LPD23 PF18838.1 ETS84473.1 - 0.032 14.0 0.5 0.066 13.0 0.5 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 peroxidase PF00141.23 ETS84475.1 - 0.045 13.4 0.4 0.086 12.5 0.3 1.7 1 1 0 1 1 1 0 Peroxidase DUF2039 PF10217.9 ETS84475.1 - 0.59 10.5 11.8 3 8.2 4.3 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2039) NUDIX PF00293.28 ETS84476.1 - 6.8e-12 45.6 0.0 1.5e-10 41.2 0.0 2.2 2 0 0 2 2 2 2 NUDIX domain Peptidase_S8 PF00082.22 ETS84479.1 - 5.1e-16 58.8 0.1 1.1e-15 57.7 0.1 1.5 1 1 0 1 1 1 1 Subtilase family NACHT PF05729.12 ETS84480.1 - 4.9e-13 49.3 0.0 4.2e-07 30.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain NB-ARC PF00931.22 ETS84480.1 - 7.5e-11 41.7 0.0 2.3e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain AAA_22 PF13401.6 ETS84480.1 - 1.2e-10 41.8 0.0 0.00038 20.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ETS84480.1 - 7.4e-10 39.5 1.9 0.00057 20.3 0.0 3.6 4 1 0 4 4 3 2 AAA ATPase domain AAA PF00004.29 ETS84480.1 - 2.2e-07 31.4 0.0 0.0026 18.2 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 ETS84480.1 - 1.4e-06 28.2 0.0 0.0039 17.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_30 PF13604.6 ETS84480.1 - 8.3e-06 25.7 0.0 0.052 13.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 ETS84480.1 - 2.2e-05 24.8 0.0 0.18 12.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ETS84480.1 - 4e-05 24.2 0.0 0.068 13.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ETS84480.1 - 4.1e-05 23.2 0.0 0.043 13.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 ETS84480.1 - 4.8e-05 23.2 0.0 0.23 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ETS84480.1 - 5.6e-05 23.2 0.0 0.34 10.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ETS84480.1 - 6.2e-05 22.7 0.0 0.25 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 ETS84480.1 - 8.3e-05 23.1 0.0 0.27 11.7 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ResIII PF04851.15 ETS84480.1 - 0.00012 22.2 0.0 0.047 13.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 ETS84480.1 - 0.0002 20.9 0.0 0.58 9.6 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein ATPase_2 PF01637.18 ETS84480.1 - 0.00025 21.1 0.0 0.66 9.8 0.0 2.6 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 ETS84480.1 - 0.00043 20.0 0.0 0.089 12.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.22 ETS84480.1 - 0.00081 19.7 0.0 0.21 12.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase RsgA_GTPase PF03193.16 ETS84480.1 - 0.002 18.1 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 ETS84480.1 - 0.0021 18.3 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RuvB_N PF05496.12 ETS84480.1 - 0.0023 17.7 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 ETS84480.1 - 0.0026 17.7 0.1 1.2 9.1 0.0 2.4 2 0 0 2 2 2 1 NTPase AAA_33 PF13671.6 ETS84480.1 - 0.0031 17.7 0.0 3.5 7.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 ETS84480.1 - 0.0032 16.8 0.0 0.054 12.7 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 ETS84480.1 - 0.0059 16.6 0.0 3.4 7.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 ETS84480.1 - 0.0074 16.5 0.1 1.6 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 ETS84480.1 - 0.0097 15.0 0.0 0.083 11.9 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein DZR PF12773.7 ETS84480.1 - 0.012 15.6 0.3 0.012 15.6 0.3 2.9 3 1 0 3 3 2 0 Double zinc ribbon TrwB_AAD_bind PF10412.9 ETS84480.1 - 0.013 14.5 0.0 8.5 5.2 0.0 2.9 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.21 ETS84480.1 - 0.015 14.7 0.0 2 7.8 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 ETS84480.1 - 0.024 14.6 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 ETS84480.1 - 0.029 13.8 0.0 3.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 ETS84480.1 - 0.029 14.1 0.1 3.2 7.6 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.14 ETS84480.1 - 0.03 14.2 0.0 7 6.6 0.0 2.9 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.18 ETS84480.1 - 0.044 13.5 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family CbiA PF01656.23 ETS84480.1 - 0.047 13.7 0.0 3.7 7.6 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase PF06745.13 ETS84480.1 - 0.12 11.7 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 KaiC SRPRB PF09439.10 ETS84480.1 - 0.14 11.6 0.0 0.48 9.8 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit His_Phos_1 PF00300.22 ETS84481.1 - 3.4e-15 56.2 0.3 1.3e-09 38.1 0.2 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) MFS_1 PF07690.16 ETS84482.1 - 3.4e-26 92.0 66.1 1.5e-15 57.0 31.8 2.7 1 1 1 3 3 3 3 Major Facilitator Superfamily Fungal_trans PF04082.18 ETS84483.1 - 1.2e-21 76.9 0.1 1.9e-21 76.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peroxidase_2 PF01328.17 ETS84484.1 - 9.4e-43 146.9 0.0 1.1e-42 146.7 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 NUDIX PF00293.28 ETS84486.1 - 1.5e-05 25.1 0.0 7e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 NUDIX domain Slx4 PF09494.10 ETS84487.1 - 1.2e-24 86.0 0.0 2.4e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Slx4 endonuclease Ribosomal_S21e PF01249.18 ETS84488.1 - 1.7e-41 140.2 0.1 1.9e-41 140.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e FAD_binding_7 PF03441.14 ETS84489.1 - 5.5e-80 267.6 1.9 7e-80 267.3 1.0 1.7 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ETS84489.1 - 7.3e-41 139.9 0.0 1.2e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.26 ETS84489.1 - 0.063 13.8 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Universal stress protein family AT_hook PF02178.19 ETS84489.1 - 4.3 7.5 15.0 5.9 7.1 4.0 2.7 2 0 0 2 2 2 0 AT hook motif OPT PF03169.15 ETS84490.1 - 1.7e-149 499.4 49.3 2.1e-131 439.6 45.1 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein DUF4176 PF13780.6 ETS84491.1 - 0.00043 20.3 0.0 0.00078 19.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4176) DUF3176 PF11374.8 ETS84492.1 - 1.5e-31 108.8 0.3 1.5e-31 108.8 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) HAD_2 PF13419.6 ETS84494.1 - 4.2e-16 59.6 0.0 7.6e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETS84494.1 - 7.4e-08 32.9 0.0 3.3e-07 30.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sulfotransfer_3 PF13469.6 ETS84494.1 - 1e-05 26.1 0.0 0.0068 16.8 0.0 2.6 1 1 0 2 2 2 2 Sulfotransferase family HAD PF12710.7 ETS84494.1 - 0.0008 19.9 0.0 0.0021 18.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Antimicrobial22 PF16047.5 ETS84494.1 - 0.0044 16.8 1.4 0.013 15.4 1.4 1.8 1 0 0 1 1 1 1 Frog antimicrobial peptide Sulfotransfer_1 PF00685.27 ETS84494.1 - 0.0081 15.7 0.0 0.18 11.3 0.0 2.2 1 1 1 2 2 2 1 Sulfotransferase domain Hydrolase_like PF13242.6 ETS84494.1 - 0.043 13.9 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 HAD-hyrolase-like DUF3176 PF11374.8 ETS84495.1 - 8.6e-33 112.8 1.0 8.6e-33 112.8 1.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3176) TPR_12 PF13424.6 ETS84496.1 - 4.7e-25 87.7 14.7 2.4e-07 31.0 0.1 6.4 3 1 4 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 ETS84496.1 - 3e-21 74.6 13.0 0.00053 19.8 0.0 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat NB-ARC PF00931.22 ETS84496.1 - 7.2e-13 48.3 0.0 1.4e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_6 PF13174.6 ETS84496.1 - 2.4e-08 34.1 10.0 0.44 11.3 0.0 7.6 7 0 0 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS84496.1 - 9.9e-07 28.9 0.1 0.045 14.0 0.0 4.9 2 2 3 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 ETS84496.1 - 1.4e-06 28.6 13.4 6.6 7.8 0.3 7.7 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS84496.1 - 1.5e-06 28.6 12.6 0.1 13.1 0.6 7.1 2 2 5 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 ETS84496.1 - 3.6e-06 26.7 6.2 2 8.9 0.0 6.6 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 ETS84496.1 - 6.2e-06 25.9 7.6 3.2 8.1 0.0 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 ETS84496.1 - 5.3e-05 23.0 7.0 3.4 7.9 0.0 6.7 7 1 0 7 7 7 2 Tetratricopeptide repeat AAA_16 PF13191.6 ETS84496.1 - 6.7e-05 23.3 0.0 0.00059 20.3 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain TPR_1 PF00515.28 ETS84496.1 - 8.4e-05 22.2 6.2 2.5 8.1 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat AAA_22 PF13401.6 ETS84496.1 - 0.00018 21.8 0.0 0.00065 20.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_20 PF14561.6 ETS84496.1 - 0.00069 19.9 7.2 9.8 6.6 0.0 6.7 6 1 1 8 8 8 1 Tetratricopeptide repeat PNP_UDP_1 PF01048.20 ETS84496.1 - 0.0009 18.6 0.0 0.0077 15.5 0.0 2.2 2 0 0 2 2 2 1 Phosphorylase superfamily TPR_16 PF13432.6 ETS84496.1 - 0.0038 17.9 3.7 0.28 11.9 0.2 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 ETS84496.1 - 1.1 10.1 8.2 4 8.3 0.0 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat Vps39_1 PF10366.9 ETS84496.1 - 1.5 9.1 6.7 12 6.2 0.1 4.5 4 2 1 5 5 5 0 Vacuolar sorting protein 39 domain 1 Peptidase_M20 PF01546.28 ETS84497.1 - 2.5e-33 115.5 0.0 3.7e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 ETS84497.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 M20_dimer PF07687.14 ETS84497.1 - 0.03 14.2 0.0 0.16 11.9 0.0 2.3 2 1 0 2 2 2 0 Peptidase dimerisation domain Transp_cyt_pur PF02133.15 ETS84498.1 - 3.2e-25 88.8 30.6 6.4e-25 87.8 30.6 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin FAD_binding_3 PF01494.19 ETS84499.1 - 2.5e-63 214.5 0.0 3e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS84499.1 - 1.1e-06 28.5 0.0 2.4e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Phe_hydrox_dim PF07976.12 ETS84499.1 - 1.8e-06 28.1 0.0 3.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 ETS84499.1 - 1.2e-05 24.8 0.3 0.00032 20.0 0.2 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS84499.1 - 9.3e-05 22.6 0.0 0.00025 21.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS84499.1 - 9.6e-05 21.6 0.0 0.00038 19.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 ETS84499.1 - 0.00012 21.4 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 ETS84499.1 - 0.00015 21.1 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ETS84499.1 - 0.00027 19.9 0.0 0.00057 18.9 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.12 ETS84499.1 - 0.00028 20.1 0.0 0.00042 19.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 ETS84499.1 - 0.00049 18.9 0.0 0.00088 18.1 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 ETS84499.1 - 0.00085 19.8 0.1 0.0019 18.7 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ETS84499.1 - 0.014 15.8 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 ETS84499.1 - 0.03 13.7 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_trans_4_5 PF16994.5 ETS84499.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl-transferase family 4 TrkA_N PF02254.18 ETS84499.1 - 0.074 13.3 0.1 0.41 10.9 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain FAD_oxidored PF12831.7 ETS84499.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.15 ETS84499.1 - 0.13 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase K_oxygenase PF13434.6 ETS84499.1 - 0.15 11.2 0.0 0.48 9.5 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 ETS84499.1 - 0.16 11.0 0.0 0.37 9.8 0.0 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A CGI-121 PF08617.10 ETS84501.1 - 4.1e-54 183.1 0.2 4.7e-54 182.9 0.2 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 PIF1 PF05970.14 ETS84502.1 - 8.3e-42 143.6 0.0 3.4e-27 95.6 0.0 2.8 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 ETS84502.1 - 1.5e-20 73.7 0.0 2.1e-18 66.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ETS84502.1 - 7.5e-14 52.3 0.0 2.8e-13 50.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain Cauli_VI PF01693.16 ETS84502.1 - 1.7e-09 37.8 0.1 4.1e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin Viral_helicase1 PF01443.18 ETS84502.1 - 1.3e-05 25.0 1.9 0.13 12.0 0.3 3.6 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.14 ETS84502.1 - 1.6e-05 23.1 0.0 0.00013 20.1 0.0 2.1 3 0 0 3 3 3 1 Helicase AAA PF00004.29 ETS84502.1 - 6.5e-05 23.4 0.0 0.00014 22.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 ETS84502.1 - 0.00031 20.6 0.1 0.014 15.2 0.0 2.3 1 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_16 PF13191.6 ETS84502.1 - 0.0011 19.4 0.0 0.0024 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.6 ETS84502.1 - 0.0011 18.8 0.1 0.0027 17.5 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain TrwB_AAD_bind PF10412.9 ETS84502.1 - 0.0015 17.5 0.0 0.0071 15.3 0.0 1.9 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 ETS84502.1 - 0.0015 18.8 0.2 0.0076 16.5 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_11 PF13086.6 ETS84502.1 - 0.0025 17.7 0.9 0.46 10.2 0.0 3.3 4 0 0 4 4 4 1 AAA domain CobA_CobO_BtuR PF02572.15 ETS84502.1 - 0.004 17.4 0.0 0.0084 16.4 0.0 1.5 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_5 PF07728.14 ETS84502.1 - 0.0057 16.6 0.0 0.014 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 ETS84502.1 - 0.0062 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 ETS84502.1 - 0.0066 16.5 0.0 0.02 14.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 ETS84502.1 - 0.0069 15.6 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DZR PF12773.7 ETS84502.1 - 0.019 15.0 2.0 0.06 13.4 2.0 1.9 1 0 0 1 1 1 0 Double zinc ribbon MeaB PF03308.16 ETS84502.1 - 0.029 13.3 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 ETS84502.1 - 0.03 14.8 0.3 0.39 11.2 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Helicase_RecD PF05127.14 ETS84502.1 - 0.043 13.7 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Helicase RsgA_GTPase PF03193.16 ETS84502.1 - 0.053 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 ETS84502.1 - 0.071 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.15 ETS84502.1 - 0.074 13.0 0.1 5.7 6.8 0.1 2.5 2 0 0 2 2 2 0 NTPase TniB PF05621.11 ETS84502.1 - 0.097 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Zeta_toxin PF06414.12 ETS84502.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_32 PF13654.6 ETS84502.1 - 0.13 11.1 0.1 0.72 8.6 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 ETS84502.1 - 0.14 11.8 0.0 0.36 10.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain KTI12 PF08433.10 ETS84502.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Sigma54_activat PF00158.26 ETS84502.1 - 0.19 11.4 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain zf-C3HC4 PF00097.25 ETS84502.1 - 0.21 11.5 2.3 0.53 10.2 2.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_recom PF13408.6 ETS84502.1 - 0.41 11.2 2.2 0.33 11.5 0.2 1.9 2 0 0 2 2 1 0 Recombinase zinc beta ribbon domain RNA_POL_M_15KD PF02150.16 ETS84502.1 - 1 9.3 3.3 1.3 9.0 1.9 1.9 2 0 0 2 2 1 0 RNA polymerases M/15 Kd subunit FAD_binding_4 PF01565.23 ETS84503.1 - 1e-24 86.8 0.9 5.3e-24 84.5 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 ETS84503.1 - 7e-11 42.1 0.0 1.4e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like HET PF06985.11 ETS84504.1 - 6e-12 46.1 4.6 5e-10 39.9 4.6 3.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GMC_oxred_N PF00732.19 ETS84504.1 - 2.9e-08 33.4 0.0 9.8e-08 31.7 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase BNR_2 PF13088.6 ETS84505.1 - 1.1e-06 28.2 0.1 0.0061 15.9 0.0 2.3 2 1 0 2 2 2 2 BNR repeat-like domain AAA PF00004.29 ETS84506.1 - 2.4e-18 66.9 0.0 6.7e-18 65.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS84506.1 - 0.0017 18.7 0.1 0.0074 16.7 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ETS84506.1 - 0.0023 18.0 0.0 0.0052 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 ETS84506.1 - 0.025 14.3 0.1 0.074 12.8 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ETS84506.1 - 0.041 14.1 0.1 0.16 12.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ETS84506.1 - 0.062 13.6 0.1 0.13 12.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain MSA-2c PF12238.8 ETS84506.1 - 0.1 12.6 0.0 0.1 12.6 0.0 3.3 3 0 0 3 3 3 0 Merozoite surface antigen 2c CPT PF07931.12 ETS84506.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 ETS84506.1 - 0.13 12.4 1.2 0.96 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Varsurf_PPLC PF03490.13 ETS84508.1 - 3.1e-07 30.2 0.0 7.4e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C p450 PF00067.22 ETS84510.1 - 2.1e-40 138.9 0.0 2.6e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 ETS84511.1 - 6.9e-12 45.9 5.3 3.7e-09 37.1 0.2 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) TPR_MLP1_2 PF07926.12 ETS84512.1 - 0.0076 16.3 1.7 0.016 15.3 1.7 1.5 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein HrpB7 PF09486.10 ETS84512.1 - 0.015 15.7 2.5 0.032 14.6 2.2 1.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF1515 PF07439.11 ETS84512.1 - 0.05 13.6 0.1 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) CBP4 PF07960.11 ETS84512.1 - 0.084 12.7 0.8 1.6 8.6 0.0 2.8 1 1 1 2 2 2 0 CBP4 HsbA PF12296.8 ETS84512.1 - 0.11 13.0 0.5 0.35 11.3 0.3 1.9 1 1 1 2 2 2 0 Hydrophobic surface binding protein A HTH_41 PF14502.6 ETS84512.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_7 PF13176.6 ETS84512.1 - 0.15 12.1 0.5 3.5 7.9 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4404 PF14357.6 ETS84512.1 - 0.41 11.3 2.6 1 10.0 2.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) HSP70 PF00012.20 ETS84513.1 - 1.8e-12 46.3 0.1 2.4e-12 45.8 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ETS84513.1 - 2.2e-05 23.5 0.0 0.002 17.0 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Pro_dh PF01619.18 ETS84515.1 - 1.2e-61 208.8 0.0 1.7e-61 208.4 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Tim17 PF02466.19 ETS84516.1 - 0.013 15.9 5.9 0.047 14.1 5.4 2.0 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family SUa-2TM PF18179.1 ETS84517.1 - 0.3 10.4 5.6 0.46 9.7 5.6 1.3 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain Sugar_tr PF00083.24 ETS84521.1 - 5.7e-118 394.6 23.7 6.5e-118 394.4 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS84521.1 - 4.1e-20 72.0 57.0 1.7e-17 63.4 26.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.6 ETS84522.1 - 4.6e-61 206.4 0.5 6.1e-61 206.0 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS84522.1 - 4.5e-53 179.6 0.2 6.1e-53 179.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS84522.1 - 1.6e-12 47.7 0.1 3.3e-12 46.7 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS84522.1 - 9.3e-07 28.6 0.0 4.2e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ETS84522.1 - 1.2e-05 24.9 0.0 1.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 ETS84522.1 - 0.0022 17.2 0.1 0.0042 16.3 0.1 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ETS84522.1 - 0.018 15.0 1.9 0.039 13.8 1.9 1.8 1 1 0 1 1 1 0 NAD(P)H-binding DFP PF04127.15 ETS84522.1 - 0.021 14.6 3.0 0.056 13.3 0.8 2.1 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein 2-Hacid_dh_C PF02826.19 ETS84522.1 - 0.036 13.4 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 ETS84522.1 - 0.043 13.8 0.5 0.13 12.2 0.2 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.19 ETS84522.1 - 0.055 12.8 0.7 0.087 12.1 0.1 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 ETS84522.1 - 0.1 12.7 0.2 0.2 11.7 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ETS84522.1 - 0.12 12.7 0.4 0.74 10.1 0.2 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Glyco_hydro_43 PF04616.14 ETS84523.1 - 8.6e-38 130.3 7.0 1.1e-37 130.0 7.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 ETS84524.1 - 3.9e-74 250.0 8.5 5.8e-74 249.4 8.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 ETS84524.1 - 6e-06 26.3 0.2 6e-06 26.3 0.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal CAP PF00188.26 ETS84525.1 - 1.5e-15 58.1 4.2 4.8e-15 56.5 4.2 1.7 1 1 0 1 1 1 1 Cysteine-rich secretory protein family MFS_1 PF07690.16 ETS84526.1 - 6e-37 127.4 53.1 3.1e-36 125.0 53.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MASE5 PF17178.4 ETS84526.1 - 1.2 8.9 10.9 4.6 7.0 10.9 2.0 1 0 0 1 1 1 0 Membrane-associated sensor DUF3671 PF12420.8 ETS84526.1 - 2.2 8.4 8.5 14 5.8 1.6 3.3 2 1 1 3 3 3 0 Protein of unknown function 4HBT_2 PF13279.6 ETS84527.1 - 8.7e-06 26.2 0.0 1.4e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily AMP-binding PF00501.28 ETS84529.1 - 9e-301 996.4 0.0 6.1e-79 265.6 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 ETS84529.1 - 1.8e-154 514.8 0.0 9.7e-49 166.3 0.0 5.2 5 1 0 5 5 5 4 Condensation domain PP-binding PF00550.25 ETS84529.1 - 1.4e-39 134.3 8.5 2.2e-09 37.5 1.1 4.9 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ETS84529.1 - 1e-10 42.4 0.2 0.049 14.6 0.0 5.1 5 0 0 5 5 5 3 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 ETS84529.1 - 0.091 12.5 0.4 56 3.4 0.0 3.9 4 0 0 4 4 4 0 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1729 PF08354.10 ETS84530.1 - 1.5e-138 461.6 0.0 2.4e-138 460.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 ETS84530.1 - 3.8e-67 227.0 0.3 5.8e-66 223.2 0.0 2.4 3 0 0 3 3 3 1 Acyl transferase domain SAT PF16073.5 ETS84530.1 - 1.3e-40 139.7 0.2 2.5e-40 138.7 0.2 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 ETS84530.1 - 9.5e-28 96.2 0.0 2e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain FAS_meander PF17951.1 ETS84530.1 - 7.6e-23 80.9 0.1 2.2e-22 79.5 0.1 1.8 1 1 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydrat_N PF13452.6 ETS84530.1 - 3.9e-06 27.0 0.0 1.5e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Ank_4 PF13637.6 ETS84531.1 - 2e-12 47.3 0.1 7.4e-10 39.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS84531.1 - 8e-11 41.2 0.0 0.00034 20.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 ETS84531.1 - 7.2e-10 39.3 0.0 1.4e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS84531.1 - 6.1e-09 36.0 0.0 4.8e-05 23.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS84531.1 - 1.1e-06 28.8 0.1 0.011 16.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat PSD5 PF07637.11 ETS84531.1 - 0.0085 16.4 1.1 0.017 15.5 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1595) Nop25 PF09805.9 ETS84531.1 - 0.018 15.5 4.9 0.029 14.8 4.9 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) bZIP_1 PF00170.21 ETS84531.1 - 0.028 14.5 9.0 0.055 13.6 9.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor HR1 PF02185.16 ETS84531.1 - 0.089 12.9 4.8 0.16 12.1 4.8 1.4 1 0 0 1 1 1 0 Hr1 repeat PIEZO PF15917.5 ETS84531.1 - 0.11 12.0 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Piezo Csm1_N PF18504.1 ETS84531.1 - 0.11 12.8 1.6 0.21 11.9 1.6 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain DUF853 PF05872.12 ETS84531.1 - 0.5 8.9 2.2 0.7 8.4 2.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) RTA1 PF04479.13 ETS84532.1 - 6.9e-49 166.3 5.1 1e-48 165.7 5.1 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3792 PF12670.7 ETS84532.1 - 0.025 14.7 1.6 0.025 14.7 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) DUF805 PF05656.14 ETS84532.1 - 0.85 10.1 7.5 0.71 10.3 5.4 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Aminotran_4 PF01063.19 ETS84533.1 - 1e-21 77.8 0.0 1.3e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV p450 PF00067.22 ETS84534.1 - 1.3e-59 202.2 0.0 1.7e-59 201.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CedA PF10729.9 ETS84534.1 - 0.11 12.4 0.4 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 Cell division activator CedA Fas_alpha_ACP PF18325.1 ETS84535.1 - 4.1e-46 157.3 0.1 2.8e-44 151.3 0.0 2.5 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 ETS84535.1 - 3.3e-43 147.7 0.2 5.6e-43 147.0 0.2 1.4 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 ETS84535.1 - 6.8e-25 88.1 0.5 9.1e-24 84.4 0.1 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ETS84535.1 - 3.9e-13 49.5 0.0 1e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain USP7_C2 PF14533.6 ETS84535.1 - 0.04 13.6 0.4 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal ACP_syn_III PF08545.10 ETS84535.1 - 0.11 12.4 0.1 0.35 10.7 0.1 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_2 PF00891.18 ETS84536.1 - 9.7e-18 64.2 0.0 1.7e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Amidase PF01425.21 ETS84538.1 - 5.1e-67 226.8 0.0 3.2e-66 224.1 0.0 2.0 1 1 0 1 1 1 1 Amidase SesA PF17107.5 ETS84539.1 - 4.9e-06 26.7 0.0 7.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3140 PF11338.8 ETS84539.1 - 0.017 15.5 0.3 0.12 12.8 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3140) Helo_like_N PF17111.5 ETS84539.1 - 0.034 13.5 0.3 0.12 11.7 0.1 1.9 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins DUF1993 PF09351.10 ETS84540.1 - 7.7e-49 165.9 0.0 8.6e-49 165.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF5427 PF10310.9 ETS84540.1 - 0.083 11.8 0.0 0.093 11.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) GST_N_2 PF13409.6 ETS84541.1 - 5.9e-23 81.0 0.0 1.3e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS84541.1 - 3.3e-15 55.9 0.0 8.4e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ETS84541.1 - 2.1e-06 27.8 0.0 3.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ETS84541.1 - 0.00031 20.9 0.0 0.00056 20.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ETS84541.1 - 0.012 16.1 0.0 0.54 10.7 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain SUKH_6 PF14568.6 ETS84541.1 - 0.072 13.5 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall GST_C_5 PF16865.5 ETS84541.1 - 0.17 12.5 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain JSRP PF15312.6 ETS84542.1 - 0.17 11.8 0.4 1.8 8.5 0.0 2.4 2 1 0 2 2 2 0 Junctional sarcoplasmic reticulum protein Pkinase PF00069.25 ETS84544.1 - 2.7e-33 115.4 0.0 4e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS84544.1 - 6.7e-18 64.9 0.0 1.7e-17 63.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS84544.1 - 0.001 18.4 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ETS84544.1 - 0.011 15.7 0.1 0.048 13.6 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETS84544.1 - 0.092 12.3 0.6 7.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase Aldolase_II PF00596.21 ETS84546.1 - 2.2e-28 99.4 0.6 2.8e-28 99.1 0.6 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain F-box-like PF12937.7 ETS84547.1 - 1.7e-05 24.6 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS84547.1 - 0.00013 21.7 0.0 0.00038 20.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain NolV PF06635.12 ETS84547.1 - 0.044 13.1 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein NolV Polysacc_deac_1 PF01522.21 ETS84548.1 - 8.4e-12 45.1 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase p450 PF00067.22 ETS84549.1 - 1.4e-75 254.9 0.0 1.7e-75 254.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HpcH_HpaI PF03328.14 ETS84550.1 - 4.1e-29 101.3 0.0 5.6e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Fungal_trans PF04082.18 ETS84551.1 - 3.7e-17 62.2 0.1 8.7e-17 61.0 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.21 ETS84552.1 - 3.5e-111 372.2 40.3 4.2e-111 371.9 40.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS84552.1 - 9.5e-33 113.6 41.2 1.2e-32 113.3 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease Methyltransf_2 PF00891.18 ETS84553.1 - 1.3e-24 86.7 0.0 1.7e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain CARD_2 PF16739.5 ETS84553.1 - 0.055 13.5 0.2 3.1 7.9 0.0 3.0 3 0 0 3 3 3 0 Caspase recruitment domain Pro_sub2 PF18513.1 ETS84554.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Prodomain subtilisin 2 Bap31 PF05529.12 ETS84554.1 - 1.6 8.6 6.0 0.21 11.5 0.2 2.5 2 1 1 3 3 3 0 Bap31/Bap29 transmembrane region YtpI PF14007.6 ETS84554.1 - 1.8 8.8 7.7 7.3 6.8 0.8 3.2 3 1 0 3 3 3 0 YtpI-like protein Ank_2 PF12796.7 ETS84555.1 - 1.8e-58 195.0 7.9 4.3e-13 49.6 0.0 8.7 5 3 3 9 9 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS84555.1 - 7.6e-40 134.8 13.9 3.7e-09 36.9 0.3 11.1 9 1 3 12 12 12 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS84555.1 - 2.1e-38 125.9 12.8 0.025 15.1 0.0 16.0 17 0 0 17 17 17 10 Ankyrin repeat Ank_5 PF13857.6 ETS84555.1 - 7.1e-36 121.8 13.6 1.9e-07 31.2 0.1 12.0 8 3 5 13 13 13 9 Ankyrin repeats (many copies) Ank PF00023.30 ETS84555.1 - 2.1e-21 75.3 16.2 0.52 10.9 0.0 12.3 14 0 0 14 14 14 7 Ankyrin repeat NACHT PF05729.12 ETS84555.1 - 1.1e-06 28.6 0.0 3.6e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS84555.1 - 9.5e-05 22.8 0.0 0.0047 17.3 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS84555.1 - 0.00051 20.3 0.0 0.027 14.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain DUF1445 PF07286.12 ETS84555.1 - 0.045 13.7 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1445) Ank_2 PF12796.7 ETS84557.1 - 2.2e-15 57.0 0.0 6.6e-10 39.4 0.0 3.4 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS84557.1 - 4.7e-09 35.8 0.5 0.011 16.2 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 ETS84557.1 - 1.5e-08 34.7 0.9 0.7 10.3 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS84557.1 - 1.6e-08 34.9 0.2 8.8e-05 23.0 0.0 4.2 3 1 2 5 5 5 3 Ankyrin repeats (many copies) NACHT PF05729.12 ETS84557.1 - 1.1e-05 25.5 0.5 7.1e-05 22.8 0.1 2.6 3 1 0 3 3 3 1 NACHT domain Ank PF00023.30 ETS84557.1 - 0.0016 18.8 0.1 6 7.5 0.0 3.9 2 1 0 2 2 2 1 Ankyrin repeat AAA_22 PF13401.6 ETS84557.1 - 0.013 15.7 0.1 0.054 13.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain HET PF06985.11 ETS84558.1 - 2.7e-28 99.2 1.6 5.3e-28 98.2 1.6 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 ETS84559.1 - 1.4e-20 73.6 0.0 1.5e-17 63.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS84559.1 - 4.1e-11 42.9 0.0 3e-10 40.1 0.0 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS84559.1 - 7e-08 32.6 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS84559.1 - 0.0076 15.7 0.0 0.0093 15.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS84559.1 - 0.066 12.6 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Fungal_trans_2 PF11951.8 ETS84560.1 - 1.7e-34 119.3 6.2 2.3e-34 118.9 6.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Flg_hook PF02120.16 ETS84560.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK DUF1324 PF07038.11 ETS84560.1 - 0.13 12.6 0.4 2.1 8.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1324) Fructosamin_kin PF03881.14 ETS84561.1 - 6.4e-35 120.7 0.0 8.2e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 ETS84561.1 - 0.00047 20.2 0.0 0.0011 18.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ETS84561.1 - 0.0045 16.3 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF2252 PF10009.9 ETS84561.1 - 0.22 10.5 0.0 0.4 9.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) NmrA PF05368.13 ETS84563.1 - 9.7e-34 116.9 0.0 2.5e-33 115.6 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS84563.1 - 1.1e-09 38.4 0.2 1.9e-09 37.7 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 ETS84563.1 - 0.011 15.9 0.1 0.026 14.8 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain adh_short_C2 PF13561.6 ETS84563.1 - 0.018 14.6 0.2 0.024 14.2 0.2 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF1932 PF09130.11 ETS84563.1 - 0.021 14.8 0.1 0.094 12.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1932) Epimerase PF01370.21 ETS84563.1 - 0.026 14.0 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS84563.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Mur_ligase PF01225.25 ETS84563.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, catalytic domain GRIP PF01465.20 ETS84564.1 - 1.4e-14 53.7 0.1 3.2e-14 52.5 0.1 1.7 1 0 0 1 1 1 1 GRIP domain Spc7 PF08317.11 ETS84564.1 - 6.1e-08 31.9 156.6 0.038 12.9 20.3 8.0 3 2 5 8 8 8 6 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 ETS84564.1 - 2.4e-07 30.8 166.6 0.0002 21.4 25.7 9.1 3 2 6 9 9 9 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 ETS84564.1 - 4.2e-05 23.0 154.7 0.0024 17.2 16.1 9.3 4 2 5 9 9 9 5 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.11 ETS84564.1 - 0.00014 20.9 40.9 0.00014 20.9 40.9 5.5 2 2 2 5 5 5 1 Calcium binding and coiled-coil domain (CALCOCO1) like WEMBL PF05701.11 ETS84564.1 - 0.00076 18.3 34.7 0.00076 18.3 34.7 3.5 2 1 1 3 3 3 1 Weak chloroplast movement under blue light AAA_13 PF13166.6 ETS84564.1 - 0.002 16.9 30.2 0.002 16.9 30.2 5.4 3 2 3 6 6 6 3 AAA domain Nup54 PF13874.6 ETS84564.1 - 0.0052 16.9 7.2 0.0052 16.9 7.2 8.6 4 2 4 8 8 6 1 Nucleoporin complex subunit 54 DHR10 PF18595.1 ETS84564.1 - 0.0056 16.7 18.0 0.0056 16.7 18.0 11.0 4 2 5 10 10 10 5 Designed helical repeat protein 10 domain Cep57_CLD PF14073.6 ETS84564.1 - 0.0085 16.1 29.9 0.0085 16.1 29.9 8.7 3 2 5 8 8 6 3 Centrosome localisation domain of Cep57 DUF745 PF05335.13 ETS84564.1 - 0.0088 15.8 12.8 0.0088 15.8 12.8 8.4 3 2 7 10 10 8 2 Protein of unknown function (DUF745) Fez1 PF06818.15 ETS84564.1 - 0.011 16.2 28.1 0.011 16.2 28.1 8.1 2 2 7 9 9 9 0 Fez1 DivIC PF04977.15 ETS84564.1 - 0.023 14.5 0.7 0.023 14.5 0.7 13.8 8 4 4 13 13 13 0 Septum formation initiator MscS_porin PF12795.7 ETS84564.1 - 0.037 13.6 145.1 0.24 10.9 3.5 7.1 4 3 1 6 6 6 0 Mechanosensitive ion channel porin domain Filament PF00038.21 ETS84564.1 - 0.05 13.2 138.7 0.31 10.6 39.2 8.4 3 2 5 8 8 8 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 ETS84564.1 - 0.11 12.5 165.3 0.15 12.1 17.2 10.3 4 3 5 9 9 9 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 ETS84564.1 - 1.4 9.1 92.8 0.75 10.0 0.4 8.4 3 1 4 9 9 9 0 Fibrinogen alpha/beta chain family FH2 PF02181.23 ETS84564.1 - 5.1 6.1 84.0 0.008 15.3 8.5 7.1 3 3 6 9 9 9 0 Formin Homology 2 Domain DUF2939 PF11159.8 ETS84564.1 - 5.6 7.5 8.3 6 7.4 0.9 4.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2939) zinc_ribbon_10 PF10058.9 ETS84565.1 - 4.1e-19 68.0 0.1 6.8e-19 67.3 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein zf-RanBP PF00641.18 ETS84565.1 - 0.081 12.3 1.0 0.18 11.2 1.0 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others GreA_GreB_N PF03449.15 ETS84565.1 - 1.2 9.3 5.2 0.28 11.3 0.5 2.1 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal DIOX_N PF14226.6 ETS84566.1 - 3.8e-18 66.3 0.0 8.7e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS84566.1 - 8.7e-14 51.8 0.0 1.5e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.24 ETS84567.1 - 1.3e-80 271.5 25.2 1.5e-80 271.3 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS84567.1 - 2.8e-22 79.1 26.6 1e-20 74.0 15.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS84567.1 - 0.00041 18.9 1.7 0.00041 18.9 1.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Amidohydro_1 PF01979.20 ETS84568.1 - 1.7e-55 188.8 0.0 2e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS84568.1 - 3.3e-13 49.9 0.0 1.8e-09 37.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 ETS84568.1 - 0.00046 19.6 0.0 0.0012 18.3 0.0 1.6 2 0 0 2 2 2 1 Adenosine/AMP deaminase MARVEL PF01284.23 ETS84569.1 - 0.00066 19.7 9.9 0.0011 19.0 9.9 1.3 1 0 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.11 ETS84569.1 - 2.1 8.2 9.5 0.19 11.6 4.6 1.6 2 0 0 2 2 2 0 7TM diverse intracellular signalling ENTH PF01417.20 ETS84570.1 - 3.1e-45 153.2 0.0 4.7e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 ETS84570.1 - 0.00039 19.5 0.0 0.00057 19.0 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF5102 PF17104.5 ETS84570.1 - 0.6 10.1 5.6 0.12 12.4 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) Pro_isomerase PF00160.21 ETS84571.1 - 4.3e-42 144.1 0.2 5.5e-42 143.7 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_pol_Rpc34 PF05158.12 ETS84572.1 - 1.8e-81 274.1 0.0 2.1e-81 273.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 ETS84572.1 - 6.2e-05 23.1 0.1 0.00015 21.9 0.1 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC TPR_1 PF00515.28 ETS84573.1 - 3.3e-41 137.5 27.8 1.4e-06 27.9 0.7 9.7 10 0 0 10 10 9 8 Tetratricopeptide repeat STI1 PF17830.1 ETS84573.1 - 4.5e-34 116.2 18.3 4.1e-19 68.3 5.1 3.0 3 0 0 3 3 3 2 STI1 domain TPR_2 PF07719.17 ETS84573.1 - 8e-32 106.8 26.7 0.00023 21.1 0.2 9.8 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_11 PF13414.6 ETS84573.1 - 6.1e-19 67.4 12.6 0.012 15.3 1.4 7.3 5 1 2 7 7 7 5 TPR repeat TPR_8 PF13181.6 ETS84573.1 - 3.8e-16 57.9 19.3 5.8e-05 23.0 0.4 7.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 ETS84573.1 - 5.7e-14 52.2 15.5 1.3e-09 38.2 0.7 5.9 3 3 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 ETS84573.1 - 6.4e-14 51.5 10.5 0.58 11.1 0.0 8.6 5 3 4 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 ETS84573.1 - 2.6e-12 47.2 6.8 0.039 14.6 0.2 5.8 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 ETS84573.1 - 5.8e-12 45.1 3.8 0.25 11.8 0.1 7.7 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 ETS84573.1 - 6.5e-12 45.8 7.4 0.054 14.0 0.1 6.5 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 ETS84573.1 - 1.1e-11 44.6 0.2 3.9e-05 23.7 0.0 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 ETS84573.1 - 7.8e-11 41.2 3.4 0.00049 19.9 0.0 6.0 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 ETS84573.1 - 3.7e-07 29.8 8.0 0.051 13.5 0.1 6.1 6 1 1 7 7 6 2 Tetratricopeptide repeat Trypan_PARP PF05887.11 ETS84573.1 - 0.0069 16.4 14.8 0.0069 16.4 14.8 2.1 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 ETS84573.1 - 0.12 11.5 4.3 0.26 10.4 4.3 1.5 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 DUF5113 PF17140.4 ETS84573.1 - 0.29 10.9 10.2 2.4 8.0 0.6 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF5113) TPR_6 PF13174.6 ETS84573.1 - 0.89 10.3 0.1 0.89 10.3 0.1 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF5486 PF17588.2 ETS84573.1 - 0.9 9.5 3.7 5.1 7.1 1.8 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5486) MIT PF04212.18 ETS84573.1 - 3.6 7.7 19.7 2.5 8.2 0.4 6.5 7 1 0 7 7 7 0 MIT (microtubule interacting and transport) domain Glyco_hydro_28 PF00295.17 ETS84574.1 - 5e-50 170.4 13.4 6.5e-50 170.0 13.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 End_N_terminal PF12218.8 ETS84574.1 - 0.033 13.9 0.9 0.17 11.6 0.0 2.5 3 0 0 3 3 3 0 N terminal extension of bacteriophage endosialidase ATP_transf PF09830.9 ETS84576.1 - 5.5e-14 52.1 0.1 9.5e-14 51.3 0.1 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4804 PF16062.5 ETS84577.1 - 5.3e-81 272.7 0.0 2.7e-44 151.7 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4804) Rad4 PF03835.15 ETS84578.1 - 3.4e-16 59.2 2.4 7.5e-16 58.1 2.4 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 ETS84578.1 - 6.6e-14 52.3 1.8 1.5e-13 51.2 1.8 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily adh_short PF00106.25 ETS84579.1 - 2.2e-21 76.2 0.0 2.9e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS84579.1 - 1.1e-16 61.2 0.0 1.4e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 ETS84579.1 - 3.4e-06 27.1 0.0 4.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS84579.1 - 0.00027 20.5 0.0 0.00057 19.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ETS84579.1 - 0.0058 16.6 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 ETS84579.1 - 0.033 14.3 0.0 0.36 10.9 0.0 2.2 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 ETS84579.1 - 0.065 12.8 0.1 0.084 12.4 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Glyco_hydro_18 PF00704.28 ETS84580.1 - 1.1e-19 71.4 0.7 1.8e-19 70.6 0.7 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ETS84580.1 - 2.7e-05 24.6 22.6 9.6e-05 22.8 22.6 2.1 1 0 0 1 1 1 1 Chitin recognition protein Sec61_beta PF03911.16 ETS84581.1 - 1.5e-18 66.5 1.5 2e-18 66.1 1.5 1.2 1 0 0 1 1 1 1 Sec61beta family CFEM PF05730.11 ETS84582.1 - 2.2e-15 56.5 13.3 3.6e-15 55.8 13.3 1.4 1 0 0 1 1 1 1 CFEM domain DUF3836 PF12930.7 ETS84582.1 - 0.74 9.6 2.1 0.65 9.8 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF3836) DUF308 PF03729.13 ETS84582.1 - 1.2 9.5 10.2 4.8 7.6 2.1 3.3 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) Tyrosinase PF00264.20 ETS84583.1 - 4.5e-37 128.5 3.0 6.6e-37 127.9 3.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase EVI2A PF05399.11 ETS84583.1 - 0.017 14.7 0.3 0.027 14.1 0.3 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Glyco_transf_28 PF03033.20 ETS84585.1 - 2.2e-18 66.6 0.2 3e-10 40.3 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 ETS84585.1 - 4.1e-06 25.9 0.0 7.3e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 ETS84585.1 - 3.9e-05 23.9 0.0 0.00014 22.2 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 ETS84585.1 - 0.0017 18.4 0.0 0.0061 16.6 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UIM PF02809.20 ETS84585.1 - 1.6 8.9 40.6 0.48 10.5 1.9 7.4 7 0 0 7 7 7 0 Ubiquitin interaction motif adh_short PF00106.25 ETS84586.1 - 4.6e-27 94.8 0.1 2.6e-25 89.0 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS84586.1 - 5.7e-17 62.1 0.2 6.4e-16 58.6 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS84586.1 - 1.3e-09 38.2 0.1 2.3e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.18 ETS84587.1 - 2.7e-12 46.3 0.0 2.7e-12 46.3 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS84587.1 - 6.4e-08 32.6 7.0 1.4e-07 31.5 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med3 PF11593.8 ETS84587.1 - 4 6.5 23.4 6.9 5.7 23.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NIF PF03031.18 ETS84588.1 - 2.8e-37 127.9 0.0 4e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RNA_pol_Rpc4 PF05132.14 ETS84588.1 - 4.1 7.8 11.2 0.4 11.1 4.6 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 Vta1 PF04652.16 ETS84590.1 - 5.8e-52 175.5 0.5 5.8e-52 175.5 0.5 1.7 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 ETS84590.1 - 1.2e-15 56.9 1.1 1.2e-15 56.9 1.1 1.7 2 0 0 2 2 2 1 Vta1 C-terminal domain Hamartin PF04388.12 ETS84590.1 - 3.3 6.3 11.4 4.5 5.8 11.4 1.3 1 0 0 1 1 1 0 Hamartin protein Thioredoxin PF00085.20 ETS84591.1 - 1.5e-32 111.6 0.1 6.7e-27 93.5 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin OST3_OST6 PF04756.13 ETS84591.1 - 4.7e-08 32.7 0.0 3.9e-07 29.7 0.0 2.0 1 1 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 ETS84591.1 - 5.6e-05 23.6 0.4 0.028 14.9 0.1 2.8 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ETS84591.1 - 0.00095 19.4 0.2 0.99 9.8 0.0 4.2 3 2 1 4 4 4 1 Thioredoxin-like TraF PF13728.6 ETS84591.1 - 0.0026 17.6 5.0 0.17 11.7 0.0 3.0 3 0 0 3 3 3 1 F plasmid transfer operon protein ERp29_N PF07912.13 ETS84591.1 - 0.0034 17.5 0.1 1.8 8.7 0.0 2.8 2 1 0 3 3 3 2 ERp29, N-terminal domain Thioredoxin_7 PF13899.6 ETS84591.1 - 0.0061 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like QSOX_Trx1 PF18108.1 ETS84591.1 - 0.0073 16.5 0.0 0.025 14.8 0.0 1.8 2 0 0 2 2 2 1 QSOX Trx-like domain ThiJ_like PF17124.5 ETS84591.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like HyaE PF07449.11 ETS84591.1 - 0.019 14.9 0.0 6.7 6.7 0.0 2.7 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 ETS84591.1 - 0.033 14.1 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family RNase_PH PF01138.21 ETS84592.1 - 1.9e-34 119.0 0.9 2.7e-34 118.5 0.9 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ETS84592.1 - 0.1 12.6 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 NhaB PF06450.12 ETS84592.1 - 0.2 10.5 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial Na+/H+ antiporter B (NhaB) Cellulase PF00150.18 ETS84594.1 - 7.1e-33 114.2 0.1 1.2e-32 113.5 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ADH_zinc_N PF00107.26 ETS84595.1 - 6.5e-26 90.8 2.0 1.2e-25 90.0 2.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS84595.1 - 2.4e-18 67.5 0.1 1.2e-17 65.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS84595.1 - 8.1e-11 41.8 0.0 1.8e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 ETS84595.1 - 0.00054 20.2 0.0 0.0025 18.1 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain AlaDh_PNT_C PF01262.21 ETS84595.1 - 0.016 14.5 0.1 0.026 13.8 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RTBV_P12 PF06361.11 ETS84595.1 - 0.1 13.0 0.1 8.7 6.8 0.0 2.9 3 1 0 3 3 3 0 Rice tungro bacilliform virus P12 protein adh_short_C2 PF13561.6 ETS84596.1 - 6.2e-64 215.7 3.5 7.1e-64 215.6 3.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS84596.1 - 1.5e-48 164.9 3.3 1.7e-48 164.7 3.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS84596.1 - 4.8e-12 46.2 3.4 6.6e-12 45.7 3.4 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ETS84596.1 - 0.012 15.5 0.2 0.024 14.5 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 ETS84596.1 - 0.013 15.0 0.7 0.044 13.2 0.7 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 ETS84596.1 - 0.054 14.2 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Sacchrp_dh_NADP PF03435.18 ETS84596.1 - 0.087 13.1 0.5 0.17 12.2 0.2 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N PF00107.26 ETS84596.1 - 0.21 11.6 3.2 2.9 7.9 3.2 2.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase TauD PF02668.16 ETS84597.1 - 1.7e-49 169.0 0.1 2e-49 168.8 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Hemerythrin PF01814.23 ETS84598.1 - 5.1e-09 36.8 1.1 7.9e-09 36.2 1.1 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain MFS_1 PF07690.16 ETS84599.1 - 1.6e-42 145.7 23.0 1.6e-42 145.7 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS84599.1 - 5.3e-07 28.9 38.1 9.9e-07 28.0 19.7 3.4 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 ETS84599.1 - 3.7e-06 26.5 1.4 3.7e-06 26.5 1.4 2.6 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Fungal_trans PF04082.18 ETS84600.1 - 1.7e-17 63.4 0.1 3.4e-17 62.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS84600.1 - 3.1e-07 30.4 17.6 3.1e-07 30.4 13.2 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0242 PF06785.11 ETS84600.1 - 4.1 7.5 5.4 9.9 6.2 0.2 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Aa_trans PF01490.18 ETS84601.1 - 2.8e-37 128.4 35.8 3.5e-37 128.1 35.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3176 PF11374.8 ETS84602.1 - 6.4e-33 113.2 4.9 4.7e-32 110.4 0.5 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3176) FAD_binding_3 PF01494.19 ETS84603.1 - 2.1e-29 102.9 0.2 1e-28 100.6 0.2 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ETS84603.1 - 3.8e-05 23.1 0.2 0.0066 15.7 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS84603.1 - 4.3e-05 22.9 0.0 0.00051 19.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS84603.1 - 0.00051 19.2 1.0 0.002 17.2 1.0 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ETS84603.1 - 0.00053 20.2 0.4 0.0022 18.2 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 ETS84603.1 - 0.0006 19.0 0.0 0.0035 16.4 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.14 ETS84603.1 - 0.003 16.5 0.7 0.0044 15.9 0.3 1.4 1 1 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.14 ETS84603.1 - 0.004 15.9 0.0 0.0081 14.9 0.0 1.4 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 ETS84603.1 - 0.007 16.9 0.1 0.039 14.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ETS84603.1 - 0.0073 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ETS84603.1 - 0.027 13.7 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 ETS84603.1 - 0.036 13.4 0.4 1.7 7.9 0.0 2.4 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 ETS84603.1 - 0.14 11.2 0.7 0.42 9.6 0.4 1.8 2 0 0 2 2 2 0 FAD binding domain Glyco_hydro_12 PF01670.16 ETS84604.1 - 1.7e-16 60.8 8.9 1.7e-16 60.8 8.9 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 GREB1 PF15782.5 ETS84604.1 - 1.2 6.1 5.4 1.4 5.9 5.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Aldedh PF00171.22 ETS84605.1 - 4.5e-145 483.7 0.0 5.2e-145 483.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family p450 PF00067.22 ETS84606.1 - 1.2e-69 235.3 0.0 2.5e-69 234.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF3817 PF12823.7 ETS84608.1 - 0.055 14.3 0.8 0.15 12.9 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3817) Abhydrolase_3 PF07859.13 ETS84609.1 - 1.1e-21 77.7 0.4 1.4e-21 77.3 0.4 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS84609.1 - 7.1e-05 21.8 0.0 0.0001 21.3 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 ETS84609.1 - 0.021 14.1 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 HU-CCDC81_bac_2 PF18175.1 ETS84610.1 - 0.14 12.1 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 Clr5 PF14420.6 ETS84611.1 - 8.8e-13 48.3 1.1 2.1e-12 47.0 0.7 1.9 2 0 0 2 2 2 1 Clr5 domain DUF5484 PF17583.2 ETS84611.1 - 0.079 12.6 0.3 0.17 11.6 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5484) API5 PF05918.11 ETS84611.1 - 1.6 7.4 3.2 23 3.6 1.4 2.1 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Pex14_N PF04695.13 ETS84611.1 - 2.9 8.5 6.8 21 5.7 0.2 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Oxidored_FMN PF00724.20 ETS84613.1 - 1e-91 307.8 0.0 1.2e-91 307.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PRAI PF00697.22 ETS84613.1 - 0.047 13.5 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase LIP PF03583.14 ETS84614.1 - 1.5e-08 34.3 0.7 0.00057 19.3 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_6 PF12697.7 ETS84614.1 - 0.00013 22.7 2.9 0.0002 22.0 2.2 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS84614.1 - 0.00013 21.3 0.4 0.0011 18.3 0.4 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS84614.1 - 0.0017 18.0 0.3 0.0036 17.0 0.3 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS84614.1 - 0.0025 17.3 1.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family ABC2_membrane PF01061.24 ETS84616.1 - 1.9e-79 266.0 59.2 3.8e-41 140.8 26.8 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 ETS84616.1 - 5.9e-37 127.2 0.0 4.7e-18 66.0 0.0 2.3 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ETS84616.1 - 5.5e-31 106.3 2.7 2.3e-28 97.9 0.1 3.9 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 ETS84616.1 - 2.2e-14 53.8 0.0 4.7e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 ETS84616.1 - 3.7e-06 26.7 0.1 0.00016 21.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ETS84616.1 - 2.9e-05 24.0 0.0 0.0055 16.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 ETS84616.1 - 8.8e-05 22.7 0.3 0.06 13.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 ETS84616.1 - 0.00013 22.4 0.3 0.0035 17.8 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 ETS84616.1 - 0.00034 21.2 0.0 0.0047 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ETS84616.1 - 0.00041 20.0 0.4 0.049 13.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.19 ETS84616.1 - 0.001 18.7 0.8 0.031 13.9 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 ETS84616.1 - 0.001 19.5 0.1 0.21 12.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.7 ETS84616.1 - 0.0019 17.4 19.0 0.0019 17.4 19.0 3.4 2 2 1 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.6 ETS84616.1 - 0.0071 16.2 0.8 1.4 8.6 0.1 2.9 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 ETS84616.1 - 0.0087 16.1 0.1 4.3 7.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.19 ETS84616.1 - 0.04 13.4 0.0 0.8 9.1 0.0 2.7 2 2 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 ETS84616.1 - 0.041 13.6 0.2 8.2 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ETS84616.1 - 0.05 13.9 1.1 1.4 9.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ETS84616.1 - 0.06 13.3 1.2 2.7 7.9 0.1 2.6 2 0 0 2 2 2 0 NACHT domain DUF3675 PF12428.8 ETS84616.1 - 0.11 13.1 3.3 2.7 8.6 0.0 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF3675) AAA_30 PF13604.6 ETS84616.1 - 0.11 12.2 0.7 2.3 7.9 0.4 2.5 2 0 0 2 2 2 0 AAA domain Pax2_C PF12403.8 ETS84616.1 - 0.18 11.9 1.9 0.26 11.4 0.2 2.1 2 0 0 2 2 2 0 Paired-box protein 2 C terminal SnoaL_4 PF13577.6 ETS84617.1 - 4e-09 36.7 0.3 4.9e-09 36.4 0.3 1.1 1 0 0 1 1 1 1 SnoaL-like domain Ribonuc_L-PSP PF01042.21 ETS84618.1 - 2.9e-08 33.7 0.1 1.3e-07 31.6 0.1 1.8 1 1 0 1 1 1 1 Endoribonuclease L-PSP NmrA PF05368.13 ETS84619.1 - 9.7e-13 48.2 0.0 5.3e-12 45.8 0.1 2.1 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ETS84619.1 - 0.00055 19.5 0.2 0.0019 17.7 0.1 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS84619.1 - 0.002 18.1 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 ETS84619.1 - 0.0074 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Pkinase PF00069.25 ETS84620.1 - 7.2e-18 64.9 0.0 6.2e-17 61.8 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS84620.1 - 2.1e-10 40.4 0.0 1.6e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Aldo_ket_red PF00248.21 ETS84621.1 - 7.7e-44 150.1 0.0 1.2e-43 149.5 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family HET PF06985.11 ETS84621.1 - 3.8e-22 79.2 2.8 8.2e-22 78.1 0.4 2.7 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 ETS84621.1 - 4.3e-20 72.2 0.0 9.2e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS84621.1 - 1.1e-16 60.9 0.0 2.1e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FAD_binding_4 PF01565.23 ETS84622.1 - 3e-25 88.6 1.0 5.4e-25 87.8 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain HET PF06985.11 ETS84623.1 - 2.7e-25 89.4 0.2 7.4e-25 88.0 0.2 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 ETS84624.1 - 4.2e-33 114.4 0.0 5.6e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS84624.1 - 6e-24 84.9 0.0 9.2e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS84624.1 - 2.6e-07 30.7 0.1 4e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS84624.1 - 0.0012 18.3 0.0 0.0047 16.4 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Amidase_3 PF01520.18 ETS84624.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase NAD_binding_10 PF13460.6 ETS84624.1 - 0.14 12.0 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding MFS_1 PF07690.16 ETS84626.1 - 2.6e-32 112.1 76.4 1.1e-26 93.6 49.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS84626.1 - 6.9e-05 21.6 24.5 6.9e-05 21.6 24.5 2.7 1 1 2 3 3 3 3 MFS/sugar transport protein Zn_clus PF00172.18 ETS84627.1 - 2.7e-08 33.8 10.4 4.8e-08 33.0 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS84627.1 - 1.5e-05 24.2 0.0 2.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Atg14 PF10186.9 ETS84627.1 - 0.097 11.7 0.7 0.15 11.1 0.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ABC_tran PF00005.27 ETS84628.1 - 4.2e-26 92.1 0.0 6.9e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ETS84628.1 - 0.00011 22.1 0.2 0.00021 21.2 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 ETS84628.1 - 0.0052 16.5 2.0 0.0081 15.9 0.8 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 ETS84628.1 - 0.0055 16.2 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETS84628.1 - 0.011 15.5 0.0 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 ETS84628.1 - 0.014 14.4 0.3 0.027 13.4 0.3 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SH PF01445.17 ETS84628.1 - 0.031 14.2 0.4 0.088 12.8 0.4 1.7 1 0 0 1 1 1 0 Viral small hydrophobic protein MMR_HSR1 PF01926.23 ETS84628.1 - 0.12 12.5 1.0 0.27 11.3 1.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 ETS84628.1 - 0.14 11.8 0.1 0.29 10.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 ETS84628.1 - 0.21 10.9 0.1 0.39 10.0 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.7 ETS84628.1 - 0.57 9.0 1.2 0.89 8.4 1.2 1.2 1 0 0 1 1 1 0 AAA-like domain DUF87 PF01935.17 ETS84628.1 - 0.94 9.5 2.3 1.6 8.8 2.3 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain TILa PF12714.7 ETS84628.1 - 1.1 9.2 7.7 2.4 8.2 0.3 2.8 2 0 0 2 2 2 0 TILa domain ABC2_membrane_3 PF12698.7 ETS84628.1 - 3.3 6.7 19.3 0.043 12.9 10.9 2.1 3 0 0 3 3 3 0 ABC-2 family transporter protein UCH PF00443.29 ETS84629.1 - 7.6e-37 127.2 0.0 1.1e-36 126.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 ETS84629.1 - 2.2e-24 85.0 1.7 3.3e-23 81.2 0.1 2.5 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 ETS84629.1 - 1.1e-22 79.6 0.1 3.5e-12 46.0 0.3 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 ETS84629.1 - 2.4e-22 79.0 11.7 2.2e-19 69.5 1.6 3.2 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 ETS84629.1 - 3.2e-16 59.8 0.3 2.3e-14 53.7 0.0 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 ETS84629.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain NifU_N PF01592.16 ETS84630.1 - 1.4e-52 177.2 0.0 1.9e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 ETS84630.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 TSCPD domain Methyltransf_16 PF10294.9 ETS84631.1 - 2.4e-28 99.0 0.0 1.7e-27 96.3 0.0 2.0 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 ETS84631.1 - 3.9e-05 23.6 0.0 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PhyH PF05721.13 ETS84632.1 - 5.1e-08 33.4 0.1 7.5e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 ETS84632.1 - 0.00038 19.3 0.0 0.24 10.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) TauD PF02668.16 ETS84632.1 - 0.055 13.3 1.1 5.4 6.7 0.7 2.6 2 1 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family GFO_IDH_MocA PF01408.22 ETS84633.1 - 1.5e-15 58.1 0.2 2e-15 57.7 0.2 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 ETS84633.1 - 0.047 14.3 0.2 0.074 13.7 0.2 1.2 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ETS84633.1 - 0.12 13.0 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short_C2 PF13561.6 ETS84634.1 - 3e-39 135.0 0.5 2e-33 115.9 0.1 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS84634.1 - 8.9e-29 100.3 6.3 2.6e-23 82.5 1.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 ETS84634.1 - 0.00097 19.1 0.3 0.013 15.4 0.4 2.2 1 1 1 2 2 2 2 KR domain PRK PF00485.18 ETS84635.1 - 7.9e-06 25.7 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 ETS84635.1 - 4e-05 22.9 0.0 6.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 ETS84635.1 - 0.00036 21.0 0.0 0.00068 20.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 ETS84635.1 - 0.00049 19.4 0.1 0.0012 18.2 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 ETS84635.1 - 0.00067 19.8 0.1 0.0036 17.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETS84635.1 - 0.0012 19.4 0.0 0.0024 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 ETS84635.1 - 0.0016 18.3 0.1 0.012 15.5 0.0 2.3 2 1 1 3 3 3 1 NTPase AAA_22 PF13401.6 ETS84635.1 - 0.0036 17.6 0.0 0.0063 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ETS84635.1 - 0.0038 16.6 0.0 0.0065 15.9 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 ETS84635.1 - 0.0089 15.6 0.0 0.033 13.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS84635.1 - 0.0092 16.4 0.0 0.012 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 ETS84635.1 - 0.011 15.6 0.0 0.032 14.2 0.0 1.8 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.22 ETS84635.1 - 0.026 14.9 0.0 0.046 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.18 ETS84635.1 - 0.031 14.0 0.1 0.059 13.1 0.1 1.4 1 0 0 1 1 1 0 Cytidylate kinase T2SSE PF00437.20 ETS84635.1 - 0.033 13.2 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.6 ETS84635.1 - 0.034 14.6 0.0 0.13 12.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.6 ETS84635.1 - 0.039 13.7 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 ETS84635.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 ETS84635.1 - 0.081 12.8 0.1 0.2 11.5 0.1 1.9 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.6 ETS84635.1 - 0.085 12.6 0.0 0.23 11.1 0.0 1.7 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 ETS84635.1 - 0.086 13.4 0.0 0.11 13.0 0.0 1.5 1 1 0 1 1 1 0 ABC transporter KTI12 PF08433.10 ETS84635.1 - 0.099 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RuvB_N PF05496.12 ETS84635.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain APS_kinase PF01583.20 ETS84635.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_11 PF13086.6 ETS84635.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ETS84635.1 - 0.13 12.4 0.0 0.57 10.4 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 ETS84635.1 - 0.15 12.4 0.1 0.26 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 ETS84635.1 - 0.16 10.9 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain ATPase PF06745.13 ETS84635.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 ETS84635.1 - 0.21 11.1 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region CUE PF02845.16 ETS84635.1 - 0.49 10.2 2.1 0.82 9.4 0.0 2.5 3 0 0 3 3 2 0 CUE domain AAA PF00004.29 ETS84636.1 - 4.5e-08 33.6 0.0 8.3e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS84636.1 - 0.00091 19.6 0.5 0.0083 16.5 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 ETS84636.1 - 0.0067 16.2 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 ETS84636.1 - 0.017 15.1 0.1 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CbiA PF01656.23 ETS84636.1 - 0.02 14.9 0.0 0.092 12.8 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 ETS84636.1 - 0.037 14.3 0.2 0.12 12.6 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ETS84636.1 - 0.13 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSF PF00482.23 ETS84637.1 - 0.067 13.2 0.4 0.15 12.1 0.4 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F ketoacyl-synt PF00109.26 ETS84640.1 - 1.2e-66 224.8 0.2 5e-66 222.9 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ETS84640.1 - 4.7e-62 209.1 0.2 1.2e-61 207.8 0.2 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 ETS84640.1 - 4e-59 200.3 0.1 5.9e-59 199.7 0.1 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ETS84640.1 - 3.3e-54 184.5 0.0 5.6e-54 183.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ETS84640.1 - 3.8e-34 117.2 0.2 1.1e-33 115.8 0.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ETS84640.1 - 3.8e-21 75.6 2.3 5e-15 55.9 0.2 2.7 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 ETS84640.1 - 9.1e-19 68.8 0.0 9.8e-18 65.5 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ETS84640.1 - 2.4e-16 59.9 0.1 1.4e-14 54.1 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 ETS84640.1 - 5.3e-16 59.2 0.0 1.5e-15 57.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS84640.1 - 1.2e-10 41.5 0.0 4.2e-10 39.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 ETS84640.1 - 3.1e-10 39.8 0.1 8.3e-09 35.2 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_25 PF13649.6 ETS84640.1 - 2.7e-09 37.6 0.0 1.3e-08 35.4 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 ETS84640.1 - 2.1e-08 34.4 0.3 1.1e-07 32.1 0.1 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.12 ETS84640.1 - 8.3e-08 32.1 0.1 3.2e-07 30.2 0.1 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.6 ETS84640.1 - 8.9e-06 25.6 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS84640.1 - 1.3e-05 25.7 0.0 6.4e-05 23.5 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.23 ETS84640.1 - 0.0004 19.8 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 ETS84640.1 - 0.0019 17.6 0.0 0.0078 15.6 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.10 ETS84640.1 - 0.2 11.5 3.7 0.086 12.7 0.2 2.3 2 0 0 2 2 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.22 ETS84641.1 - 3.3e-47 161.3 0.0 4.4e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TAT_signal PF10518.9 ETS84641.1 - 0.36 10.7 4.6 1 9.3 4.6 1.8 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence MFS_1 PF07690.16 ETS84642.1 - 1.1e-31 110.1 59.2 2.5e-26 92.5 31.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CPP1-like PF11833.8 ETS84642.1 - 7.7 6.1 11.0 1.3 8.7 0.2 3.1 2 1 1 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like ABC_tran PF00005.27 ETS84643.1 - 5.6e-47 159.7 0.0 8.5e-27 94.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS84643.1 - 4.4e-30 105.3 26.3 3.5e-23 82.6 15.0 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ETS84643.1 - 2.3e-12 46.8 0.7 1.7e-05 24.4 0.2 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ETS84643.1 - 7.5e-07 29.5 0.0 0.0029 17.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 ETS84643.1 - 2.1e-06 27.8 0.2 1.2 8.9 0.1 3.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 ETS84643.1 - 1.5e-05 25.5 0.0 0.45 10.9 0.0 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS84643.1 - 4.3e-05 24.0 0.0 0.02 15.3 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 ETS84643.1 - 6.6e-05 22.6 0.1 0.0044 16.7 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 ETS84643.1 - 0.00019 21.6 0.0 0.24 11.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ETS84643.1 - 0.00033 20.6 0.1 0.079 12.9 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 ETS84643.1 - 0.00059 20.4 0.0 1.4 9.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ETS84643.1 - 0.00061 20.3 0.0 0.3 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 ETS84643.1 - 0.00066 19.5 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 ETS84643.1 - 0.0028 17.2 0.1 1.8 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 ETS84643.1 - 0.0037 17.0 1.0 0.52 10.0 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein ATPase_2 PF01637.18 ETS84643.1 - 0.0044 17.0 0.0 2.1 8.2 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 ETS84643.1 - 0.0054 16.8 0.0 0.42 10.7 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 ETS84643.1 - 0.007 15.7 0.0 2.2 7.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.6 ETS84643.1 - 0.016 15.2 0.0 0.99 9.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 ETS84643.1 - 0.02 14.4 0.0 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 ETS84643.1 - 0.023 14.4 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 ETS84643.1 - 0.024 14.4 0.0 1.2 8.9 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 ETS84643.1 - 0.031 14.2 0.0 0.64 9.9 0.0 2.5 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.21 ETS84643.1 - 0.073 12.4 0.0 7.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.20 ETS84643.1 - 0.084 12.8 0.1 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.22 ETS84643.1 - 0.12 12.7 0.0 4.8 7.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 ETS84643.1 - 0.13 12.3 0.2 4.8 7.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 ETS84643.1 - 0.13 12.2 0.0 17 5.4 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 ETS84643.1 - 0.14 12.1 0.1 14 5.5 0.0 2.7 2 1 1 3 3 3 0 Rad17 P-loop domain DEAD PF00270.29 ETS84643.1 - 0.15 11.8 0.1 0.51 10.1 0.1 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase CDC48_2 PF02933.17 ETS84645.1 - 0.00021 21.0 6.9 12 5.8 0.0 6.3 4 4 2 6 6 6 1 Cell division protein 48 (CDC48), domain 2 DBD_Tnp_Hermes PF10683.9 ETS84645.1 - 0.00086 18.9 7.7 17 5.1 0.1 6.2 1 1 4 6 6 6 1 Hermes transposase DNA-binding domain DUF4573 PF15140.6 ETS84645.1 - 0.0011 18.7 0.0 0.0057 16.5 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4573) Rieske_3 PF18465.1 ETS84645.1 - 0.0083 16.4 1.6 68 3.8 0.0 4.6 1 1 4 5 5 5 0 Rieske 3Fe-4S Spore-coat_CotZ PF10612.9 ETS84645.1 - 0.029 14.5 0.7 22 5.2 0.1 3.4 1 1 2 3 3 3 0 Spore coat protein Z DUF1996 PF09362.10 ETS84647.1 - 6.4e-85 284.9 2.3 8.2e-85 284.5 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 ETS84647.1 - 4.8e-20 71.5 10.2 4.8e-20 71.5 10.2 2.4 3 0 0 3 3 3 1 WSC domain CoA_transf_3 PF02515.17 ETS84649.1 - 4e-39 134.8 0.0 2.5e-35 122.3 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III Sugar_tr PF00083.24 ETS84650.1 - 1.3e-79 268.1 23.0 1.6e-79 267.9 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS84650.1 - 1.6e-20 73.3 56.4 4.9e-11 42.2 1.9 2.2 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS84650.1 - 0.24 10.2 19.8 0.011 14.7 8.2 2.4 2 0 0 2 2 2 0 MFS_1 like family Fungal_trans_2 PF11951.8 ETS84651.1 - 7.1e-07 28.4 0.8 1.6e-06 27.2 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF4106 PF13388.6 ETS84651.1 - 3.7 6.7 6.8 5.5 6.1 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) MIOX PF05153.15 ETS84652.1 - 2.7e-126 420.2 1.9 3.5e-126 419.9 1.9 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HAUS5 PF14817.6 ETS84652.1 - 0.02 13.7 2.4 0.027 13.3 2.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 MFS_1 PF07690.16 ETS84653.1 - 2.8e-35 121.9 41.1 1.4e-29 103.2 35.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ETS84653.1 - 2.5e-10 40.2 17.5 4.1e-10 39.5 17.5 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 ETS84653.1 - 6.5e-05 21.5 3.3 6.5e-05 21.5 3.3 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ETS84654.1 - 2e-21 76.3 33.2 1.8e-14 53.4 24.1 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS84654.1 - 0.31 9.9 25.9 0.74 8.6 5.0 2.8 2 1 1 3 3 3 0 Sugar (and other) transporter DUF4537 PF15057.6 ETS84655.1 - 0.15 12.1 0.0 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) Glyco_hydro_3_C PF01915.22 ETS84656.1 - 2.1e-63 214.0 0.0 3.5e-63 213.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS84656.1 - 5.2e-44 150.9 0.0 9e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS84656.1 - 1.6e-25 89.0 0.4 3.6e-25 87.8 0.4 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 ETS84656.1 - 5.9e-18 65.1 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 PA14 domain FTA4 PF13093.6 ETS84657.1 - 2.6e-60 203.8 2.5 3.2e-60 203.5 2.5 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Golgin_A5 PF09787.9 ETS84657.1 - 0.094 12.2 5.4 0.098 12.1 4.5 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF1465 PF07323.12 ETS84657.1 - 0.22 11.4 4.7 0.31 10.9 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) DivIC PF04977.15 ETS84657.1 - 0.45 10.3 7.2 0.12 12.2 3.0 2.2 2 0 0 2 2 2 0 Septum formation initiator TraC PF07820.12 ETS84657.1 - 3.7 7.9 7.6 4.3 7.7 0.0 2.9 3 1 1 4 4 4 0 TraC-like protein DUF4140 PF13600.6 ETS84657.1 - 9.2 6.8 9.5 1.7 9.1 4.5 2.3 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Peptidase_C2 PF00648.21 ETS84658.1 - 5.7e-61 206.1 0.7 1.4e-40 139.2 0.3 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease HET PF06985.11 ETS84659.1 - 8.2e-25 87.9 0.3 1.5e-24 87.0 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TIM PF00121.18 ETS84660.1 - 1.7e-53 181.5 0.0 1.9e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.18 ETS84661.1 - 1.1e-44 151.7 0.2 1.3e-44 151.6 0.2 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Dak1 PF02733.17 ETS84662.1 - 4.8e-100 334.4 0.0 6.5e-100 334.0 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 ETS84662.1 - 4.7e-42 143.8 0.3 1e-41 142.7 0.3 1.6 1 0 0 1 1 1 1 DAK2 domain DUF5484 PF17583.2 ETS84662.1 - 0.18 11.5 0.2 0.48 10.1 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5484) NAD_binding_11 PF14833.6 ETS84663.1 - 6.7e-40 136.1 0.0 1.3e-26 93.3 0.0 2.4 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 ETS84663.1 - 2.2e-35 122.1 0.4 3.8e-35 121.4 0.4 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ETS84663.1 - 5.2e-06 27.0 0.1 2.6e-05 24.7 0.0 2.1 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 ETS84663.1 - 0.0019 18.1 0.3 0.004 17.0 0.3 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 ETS84663.1 - 0.0076 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 ETS84663.1 - 0.031 13.8 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 ETS84663.1 - 0.076 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F_bP_aldolase PF01116.20 ETS84664.1 - 2.5e-84 283.1 0.0 2.8e-84 282.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II zf-UBR PF02207.20 ETS84665.1 - 1.4e-13 50.7 7.2 1.4e-13 50.7 7.2 3.3 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.23 ETS84666.1 - 5.9e-101 336.2 1.4 1.6e-100 334.9 0.0 2.0 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 ETS84666.1 - 3.8e-39 133.4 0.2 7.2e-39 132.5 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 ETS84666.1 - 1.3e-37 129.4 34.8 1.3e-37 129.4 34.8 2.0 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 ETS84666.1 - 1.3e-23 83.2 0.3 3.5e-23 81.8 0.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ETS84666.1 - 1e-14 55.0 0.1 3e-14 53.5 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ETS84666.1 - 8.6e-08 31.8 0.0 5.5e-06 25.9 0.0 2.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ETS84666.1 - 4.6e-06 26.7 0.0 1.1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ETS84666.1 - 0.0024 17.7 0.1 0.016 15.1 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ETS84666.1 - 0.0034 17.1 0.2 0.025 14.3 0.2 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Linker_histone PF00538.19 ETS84666.1 - 0.054 13.9 0.0 1.7 9.1 0.0 2.7 2 0 0 2 2 2 0 linker histone H1 and H5 family FAD_binding_4 PF01565.23 ETS84667.1 - 8.7e-23 80.6 2.8 2e-22 79.4 2.8 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS84667.1 - 2.7e-10 40.2 0.0 5.3e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like LapA_dom PF06305.11 ETS84668.1 - 0.098 12.5 10.3 1.1 9.1 0.9 3.8 3 1 1 4 4 4 0 Lipopolysaccharide assembly protein A domain Myticin-prepro PF10690.9 ETS84668.1 - 0.17 12.1 1.5 0.28 11.4 0.3 1.9 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel Shisa PF13908.6 ETS84668.1 - 4.7 7.4 5.5 0.56 10.4 1.0 1.8 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator MFS_1 PF07690.16 ETS84669.1 - 5.3e-37 127.6 36.1 5.3e-37 127.6 36.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UPF0182 PF03699.13 ETS84669.1 - 0.19 9.8 3.8 0.29 9.2 3.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) adh_short_C2 PF13561.6 ETS84670.1 - 1.2e-49 169.0 0.0 1.5e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS84670.1 - 7.8e-44 149.5 0.0 1e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS84670.1 - 2e-09 37.6 0.0 2.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS84670.1 - 0.0067 15.9 0.1 0.02 14.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F_bP_aldolase PF01116.20 ETS84671.1 - 9.5e-81 271.3 0.2 1.1e-80 271.2 0.2 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II LacAB_rpiB PF02502.18 ETS84672.1 - 1.9e-44 151.0 0.0 2.1e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 ETS84672.1 - 0.024 14.7 0.4 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Glycine-rich SFCGS KptA_kDCL PF18176.1 ETS84672.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain Fungal_trans_2 PF11951.8 ETS84673.1 - 1.1e-08 34.3 0.0 0.0004 19.3 0.0 2.8 2 1 1 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS84673.1 - 4.7e-07 29.8 7.2 1e-06 28.8 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dak1 PF02733.17 ETS84674.1 - 4.4e-96 321.4 0.0 6.6e-96 320.9 0.0 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 ETS84674.1 - 9.3e-41 139.6 4.9 9.8e-41 139.5 2.9 1.9 2 0 0 2 2 2 1 DAK2 domain RP1-2 PF12042.8 ETS84674.1 - 0.00055 19.9 2.4 0.00055 19.9 2.4 2.4 2 0 0 2 2 2 1 Tubuliform egg casing silk strands structural domain Ldh_1_N PF00056.23 ETS84674.1 - 0.09 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain CDH-cyt PF16010.5 ETS84675.1 - 1.1e-51 175.1 2.2 1.2e-51 174.9 2.2 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase INTAP PF16617.5 ETS84675.1 - 2.7 8.4 5.1 4.8 7.6 5.1 1.7 1 1 0 1 1 1 0 Intersectin and clathrin adaptor AP2 binding region Peptidase_M13_N PF05649.13 ETS84676.1 - 8.7e-84 282.4 0.0 1.1e-83 282.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ETS84676.1 - 9.8e-60 201.7 2.4 1.7e-59 200.9 2.4 1.4 1 0 0 1 1 1 1 Peptidase family M13 HXXEE PF13787.6 ETS84676.1 - 0.13 13.1 0.2 0.86 10.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif SNARE PF05739.19 ETS84676.1 - 0.64 10.1 1.9 1.4 8.9 1.9 1.6 1 0 0 1 1 1 0 SNARE domain Sel1 PF08238.12 ETS84677.1 - 4.8e-27 93.8 34.5 0.00011 22.7 0.2 11.9 13 0 0 13 13 13 7 Sel1 repeat DUF4328 PF14219.6 ETS84677.1 - 0.0037 16.8 0.3 0.01 15.4 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) TPR_6 PF13174.6 ETS84677.1 - 1.9 9.3 9.9 31 5.5 0.0 5.4 6 1 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 ETS84678.1 - 3.1e-12 46.8 4.0 0.088 13.7 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 ETS84678.1 - 0.086 11.6 0.0 0.21 10.3 0.0 1.6 2 1 0 2 2 2 0 Nup133 N terminal like FRG1 PF06229.12 ETS84679.1 - 2.1e-50 171.1 0.4 3.1e-50 170.6 0.4 1.2 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 ETS84679.1 - 0.013 15.7 0.4 0.25 11.6 0.0 2.6 1 1 2 3 3 3 0 Fascin domain 2OG-FeII_Oxy PF03171.20 ETS84680.1 - 0.0095 16.4 0.0 0.027 15.0 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FAM180 PF15173.6 ETS84680.1 - 0.062 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 FAM180 family DUF3176 PF11374.8 ETS84681.1 - 1.5e-23 83.0 0.1 3.5e-23 81.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Cyt_bd_oxida_I PF01654.17 ETS84681.1 - 0.0017 17.0 0.6 0.0047 15.6 0.3 1.7 2 0 0 2 2 2 1 Cytochrome bd terminal oxidase subunit I AIM3 PF17096.5 ETS84681.1 - 0.21 12.5 0.3 0.49 11.4 0.3 1.5 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Fungal_trans PF04082.18 ETS84682.1 - 1.3e-10 40.7 0.1 2.3e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS84682.1 - 2.2e-05 24.5 7.9 4.2e-05 23.6 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 ETS84684.1 - 8.8e-52 176.4 0.0 1.1e-51 176.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3843 PF12954.7 ETS84684.1 - 0.17 10.8 0.0 0.38 9.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3843) LCM PF04072.14 ETS84685.1 - 2.5e-17 63.4 0.1 4.3e-17 62.7 0.1 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase adh_short PF00106.25 ETS84686.1 - 3.9e-13 49.3 0.0 1.4e-12 47.4 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS84686.1 - 3.6e-09 36.5 0.0 3.5e-08 33.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS84686.1 - 2.2e-05 24.5 0.1 4.2e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS84686.1 - 0.0022 17.5 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS84686.1 - 0.0086 16.0 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_transf_4 PF13439.6 ETS84686.1 - 0.029 14.4 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 ApbA PF02558.16 ETS84686.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AMP-binding PF00501.28 ETS84687.1 - 4.1e-66 223.3 0.0 5.8e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS84687.1 - 2e-07 31.9 0.2 5.7e-07 30.4 0.2 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SDA1 PF05285.12 ETS84688.1 - 0.0016 18.0 2.2 0.0017 17.8 2.2 1.1 1 0 0 1 1 1 1 SDA1 Thioesterase PF00975.20 ETS84689.1 - 0.00072 19.7 0.0 0.0061 16.7 0.0 2.0 1 1 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 ETS84689.1 - 0.0011 18.8 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.13 ETS84689.1 - 0.0028 17.5 0.0 0.026 14.4 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.11 ETS84689.1 - 0.0032 16.9 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2974 PF11187.8 ETS84689.1 - 0.016 14.7 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 ETS84689.1 - 0.046 14.3 0.2 0.057 14.0 0.2 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ETS84689.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.3 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ETS84689.1 - 0.087 12.6 0.0 5.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ETS84689.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 ETS84689.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme GST_C_3 PF14497.6 ETS84690.1 - 4.7e-15 55.6 0.1 1.6e-14 53.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ETS84690.1 - 4.4e-11 43.0 0.0 7.5e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ETS84690.1 - 2.4e-06 27.7 0.0 1.9e-05 24.8 0.0 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ETS84690.1 - 9.8e-06 25.8 0.0 2.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ETS84690.1 - 1.6e-05 25.2 0.0 2.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS84690.1 - 0.00012 22.0 0.0 0.00063 19.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain LolA_like PF17131.4 ETS84690.1 - 0.075 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein-sorting protein GST_N_4 PF17172.4 ETS84690.1 - 0.081 13.7 0.0 0.18 12.6 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Cyclin_N2 PF16500.5 ETS84691.1 - 0.037 14.8 0.6 0.085 13.6 0.6 1.6 1 0 0 1 1 1 0 N-terminal region of cyclin_N Fungal_trans PF04082.18 ETS84693.1 - 4.9e-20 71.7 1.9 1e-19 70.6 1.9 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS84693.1 - 7.6e-09 35.5 10.3 1.4e-08 34.7 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RuBisCO_small PF00101.20 ETS84693.1 - 0.11 12.4 0.2 4.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain adh_short PF00106.25 ETS84694.1 - 4.3e-20 72.0 0.0 2.9e-19 69.3 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS84694.1 - 4.7e-10 39.4 0.0 7.3e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS84694.1 - 5.3e-06 26.5 0.1 7.9e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 KR domain NACHT PF05729.12 ETS84698.1 - 3.3e-15 56.4 0.0 6.5e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 ETS84698.1 - 2.9e-11 43.1 0.1 1.3e-10 41.0 0.1 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily AAA PF00004.29 ETS84698.1 - 4.4e-06 27.1 0.0 2.8e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ETS84698.1 - 2.3e-05 24.5 0.0 0.1 12.6 0.0 3.3 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 ETS84698.1 - 0.00023 21.6 0.1 0.00084 19.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 ETS84698.1 - 0.0022 18.0 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 ETS84698.1 - 0.013 14.7 0.0 0.037 13.2 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.6 ETS84698.1 - 0.022 15.0 0.0 0.066 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ETS84698.1 - 0.1 12.2 0.0 0.28 10.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain GMC_oxred_N PF00732.19 ETS84699.1 - 3.1e-53 181.1 0.0 4.5e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS84699.1 - 1.4e-31 109.9 0.0 3.4e-31 108.7 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 ETS84699.1 - 7.7e-07 29.0 0.9 0.00077 19.1 0.3 2.8 3 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS84699.1 - 3.1e-05 23.2 0.2 0.004 16.3 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS84699.1 - 8.5e-05 22.7 0.5 0.00022 21.4 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS84699.1 - 0.00034 19.9 0.0 0.00093 18.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS84699.1 - 0.00069 18.8 0.0 0.00098 18.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ETS84699.1 - 0.02 14.1 0.0 0.044 13.0 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS84699.1 - 0.035 12.8 0.2 0.22 10.2 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 ETS84699.1 - 0.064 13.5 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 ETS84699.1 - 0.12 12.4 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 ETS84699.1 - 0.15 11.3 0.2 0.26 10.5 0.2 1.3 1 0 0 1 1 1 0 Thi4 family adh_short PF00106.25 ETS84700.1 - 4.2e-15 55.7 0.0 9.5e-11 41.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 ETS84700.1 - 0.00014 21.8 0.0 0.00063 19.7 0.0 1.8 2 0 0 2 2 2 1 KR domain RHS PF03527.14 ETS84700.1 - 4.8 7.0 5.3 13 5.7 0.2 3.1 3 0 0 3 3 3 0 RHS protein Sugar_tr PF00083.24 ETS84701.1 - 1.3e-84 284.7 30.9 1.5e-84 284.5 30.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS84701.1 - 1.6e-12 47.0 49.7 2.5e-10 39.8 17.4 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS84701.1 - 3.7e-06 25.8 18.6 0.0036 15.9 6.5 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein EVE PF01878.18 ETS84702.1 - 1.7e-46 157.8 0.0 3.7e-46 156.7 0.0 1.6 1 0 0 1 1 1 1 EVE domain Mitofilin PF09731.9 ETS84702.1 - 3.3 6.4 19.5 4.2 6.1 19.5 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Peptidase_S64 PF08192.11 ETS84702.1 - 3.5 6.0 8.8 4.2 5.7 8.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 Ndc1_Nup PF09531.10 ETS84702.1 - 3.6 6.2 12.5 4.6 5.8 12.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ORC6 PF05460.13 ETS84702.1 - 3.7 6.7 15.6 5.6 6.1 15.6 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF4770 PF15994.5 ETS84702.1 - 7 6.9 9.6 6 7.1 7.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) NST1 PF13945.6 ETS84702.1 - 8.9 6.4 13.5 16 5.6 13.5 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Apt1 PF10351.9 ETS84702.1 - 9.2 5.0 10.5 12 4.6 10.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain U3_assoc_6 PF08640.11 ETS84703.1 - 5.4e-24 84.1 0.2 3.8e-23 81.4 0.0 2.3 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 ETS84703.1 - 0.0003 21.3 0.0 2.5 9.2 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat NRDE-2 PF08424.10 ETS84703.1 - 0.0024 17.1 0.4 0.004 16.3 0.4 1.3 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference HAT PF02184.16 ETS84703.1 - 0.033 14.1 0.1 8.1 6.5 0.0 3.2 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat TPR_16 PF13432.6 ETS84703.1 - 0.079 13.6 0.4 2.3 9.0 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 ETS84703.1 - 0.088 13.2 0.0 1.2e+02 3.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Frag1 PF10277.9 ETS84704.1 - 1.9e-38 132.2 10.9 1.9e-38 132.2 10.9 2.8 2 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 ETS84704.1 - 0.061 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Amidase PF01425.21 ETS84705.1 - 8.5e-71 239.2 0.9 2.7e-67 227.7 0.1 2.2 2 0 0 2 2 2 2 Amidase Peptidase_C80 PF11713.8 ETS84705.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase C80 family HK PF02110.15 ETS84706.1 - 2e-73 246.8 5.3 3.4e-73 246.1 5.3 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 ETS84706.1 - 1e-58 197.6 1.2 2.1e-58 196.6 1.2 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 ETS84706.1 - 0.0073 15.8 1.7 0.0073 15.8 1.7 2.0 2 1 0 3 3 3 1 Carbohydrate kinase ADH_zinc_N PF00107.26 ETS84706.1 - 0.07 13.1 0.4 0.07 13.1 0.4 2.6 3 0 0 3 3 3 0 Zinc-binding dehydrogenase DLH PF01738.18 ETS84706.1 - 0.091 12.3 0.2 0.17 11.4 0.2 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF919 PF06034.11 ETS84707.1 - 0.0068 16.2 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF919) Vac_Fusion PF02346.16 ETS84707.1 - 0.19 11.4 0.1 0.4 10.3 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 BP28CT PF08146.12 ETS84708.1 - 8e-41 139.5 0.0 2.8e-40 137.7 0.0 2.1 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 ETS84708.1 - 3.5e-24 85.4 0.3 3.5e-24 85.4 0.3 5.3 4 1 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 V-ATPase_H_N PF03224.14 ETS84708.1 - 0.0029 17.0 5.4 0.18 11.0 0.9 3.6 2 1 0 2 2 2 2 V-ATPase subunit H HEAT PF02985.22 ETS84708.1 - 0.026 14.8 13.6 0.13 12.6 0.1 5.9 6 0 0 6 6 6 0 HEAT repeat HEAT_2 PF13646.6 ETS84708.1 - 0.24 11.8 18.2 0.56 10.6 1.1 5.7 6 1 0 6 6 6 0 HEAT repeats Aminotran_1_2 PF00155.21 ETS84709.1 - 1.7e-80 270.9 0.0 2.5e-80 270.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ETS84709.1 - 0.00012 20.8 0.0 0.00029 19.5 0.0 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ETS84709.1 - 0.00023 20.3 0.0 0.00042 19.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ETS84709.1 - 0.032 13.5 0.1 0.065 12.5 0.1 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DuffyBP_N PF12377.8 ETS84709.1 - 0.07 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Duffy binding protein N terminal DUF2278 PF10042.9 ETS84710.1 - 1.9e-66 224.0 1.0 2.1e-66 223.9 1.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2278) Lipase_GDSL_2 PF13472.6 ETS84711.1 - 2e-20 73.9 0.2 4.2e-20 72.9 0.2 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS84711.1 - 4.4e-11 43.1 0.0 6.2e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 ETS84711.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family AA_permease PF00324.21 ETS84712.1 - 1.7e-112 376.5 39.9 2.1e-112 376.2 39.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS84712.1 - 6e-33 114.3 46.7 7.2e-33 114.0 46.7 1.0 1 0 0 1 1 1 1 Amino acid permease PsbQ PF05757.11 ETS84713.1 - 0.24 11.1 0.2 0.32 10.7 0.2 1.1 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) NmrA PF05368.13 ETS84714.1 - 1.3e-35 123.1 0.0 1.7e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS84714.1 - 7.5e-12 45.5 0.0 9.9e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS84714.1 - 4.8e-05 22.9 0.0 8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS84714.1 - 0.0069 15.8 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ETS84714.1 - 0.0076 15.5 0.1 0.063 12.4 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 ETS84714.1 - 0.01 15.8 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 ETS84714.1 - 0.03 13.4 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 ETS84714.1 - 0.031 13.7 0.1 0.057 12.9 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 ETS84714.1 - 0.044 14.0 0.2 0.11 12.8 0.2 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Formyl_trans_N PF00551.19 ETS84714.1 - 0.049 13.4 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Formyl transferase UPRTase PF14681.6 ETS84714.1 - 0.078 12.4 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase SnoaL PF07366.12 ETS84715.1 - 0.00076 19.3 0.0 0.0031 17.3 0.0 1.8 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase DUF1772 PF08592.11 ETS84716.1 - 2.5e-25 89.4 0.5 3.4e-25 88.9 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) p450 PF00067.22 ETS84717.1 - 1e-49 169.5 0.0 1.4e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 ETS84718.1 - 7.1e-18 65.0 0.5 3.1e-16 59.5 0.5 2.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS84718.1 - 4.1e-09 36.1 0.1 0.0022 17.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS84718.1 - 3.1e-08 32.7 0.5 0.0011 17.8 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 ETS84718.1 - 4.6e-08 32.6 0.3 1.5e-07 30.9 0.1 1.8 1 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 ETS84718.1 - 2.2e-07 30.8 0.7 0.00071 19.2 0.7 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ETS84718.1 - 1.8e-05 24.3 0.1 5e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS84718.1 - 6.1e-05 23.2 0.0 0.00016 21.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS84718.1 - 0.0002 20.7 0.0 0.0041 16.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS84718.1 - 0.00078 19.9 0.3 0.14 12.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS84718.1 - 0.0013 17.9 0.2 0.0059 15.7 0.1 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ETS84718.1 - 0.0021 17.4 0.2 0.0069 15.7 0.2 1.9 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ETS84718.1 - 0.022 14.0 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 ETS84718.1 - 0.023 13.6 0.2 3.6 6.3 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 ETS84718.1 - 0.071 12.2 0.1 1.3 8.0 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein MCRA PF06100.11 ETS84718.1 - 0.082 11.7 0.4 0.16 10.8 0.0 1.6 2 0 0 2 2 2 0 MCRA family Amino_oxidase PF01593.24 ETS84718.1 - 0.096 12.0 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 ETS84718.1 - 0.15 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Transp_cyt_pur PF02133.15 ETS84719.1 - 1.4e-101 340.5 38.2 1.8e-101 340.1 38.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Gate PF07670.14 ETS84719.1 - 6.9 7.0 13.2 4.1 7.7 1.3 3.9 4 1 0 4 4 4 0 Nucleoside recognition DIOX_N PF14226.6 ETS84720.1 - 7e-26 91.3 0.0 1.2e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS84720.1 - 2.6e-23 82.4 0.0 5e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidase PF01425.21 ETS84721.1 - 9.9e-73 245.6 0.6 1.9e-72 244.7 0.6 1.4 1 1 0 1 1 1 1 Amidase Isochorismatase PF00857.20 ETS84721.1 - 2.1e-41 142.0 0.0 4.1e-41 141.1 0.0 1.5 1 0 0 1 1 1 1 Isochorismatase family Ricin_B_lectin PF00652.22 ETS84722.1 - 2.8e-08 34.1 0.4 1.8e-05 25.0 0.0 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 ETS84722.1 - 0.0076 17.0 0.3 2.6 8.9 0.1 2.8 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Peptidase_M14 PF00246.24 ETS84723.1 - 1.9e-65 221.6 0.2 2.5e-65 221.2 0.2 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase SnoaL_4 PF13577.6 ETS84724.1 - 1.7e-05 25.0 0.0 2.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain DnaJ_CXXCXGXG PF00684.19 ETS84725.1 - 9.3e-15 54.8 69.5 8.4e-05 22.9 6.5 5.3 1 1 2 3 3 3 2 DnaJ central domain zinc-ribbons_6 PF07191.12 ETS84725.1 - 0.0059 16.6 63.6 0.61 10.1 8.8 5.4 1 1 5 7 7 7 6 zinc-ribbons MspA PF09203.11 ETS84725.1 - 0.79 9.6 4.0 39 4.0 0.0 3.7 2 1 0 2 2 2 0 MspA DZR PF12773.7 ETS84725.1 - 2.2 8.4 56.4 65 3.7 13.0 5.8 1 1 4 5 5 5 0 Double zinc ribbon TackOD1 PF18551.1 ETS84725.1 - 9.8 5.8 60.6 0.034 13.8 4.9 5.7 1 1 4 5 5 5 0 Thaumarchaeal output domain 1 FMO-like PF00743.19 ETS84726.1 - 3.3e-32 111.6 0.0 1.5e-16 59.9 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ETS84726.1 - 2e-12 47.0 0.1 8.6e-08 31.8 0.0 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS84726.1 - 2.8e-12 46.5 0.0 2.4e-08 33.6 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS84726.1 - 6e-09 35.5 0.0 1.8e-06 27.3 0.0 2.6 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ETS84726.1 - 1e-05 25.7 0.3 8.3e-05 22.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS84726.1 - 0.00025 20.8 4.4 0.0051 16.4 0.3 3.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS84726.1 - 0.00025 21.0 5.4 0.00081 19.4 0.6 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 ETS84726.1 - 0.00078 18.7 0.4 0.014 14.6 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Glu_dehyd_C PF16912.5 ETS84726.1 - 0.013 15.0 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 ETS84726.1 - 0.02 15.0 0.2 7.4 6.6 0.0 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 ETS84726.1 - 0.14 12.7 1.8 5.6 7.6 0.1 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_10 PF00331.20 ETS84727.1 - 2.1e-101 339.2 0.0 2.6e-101 338.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Sporozoite_P67 PF05642.11 ETS84727.1 - 2.4 6.1 18.0 9.4 4.2 18.0 1.9 1 1 0 1 1 1 0 Sporozoite P67 surface antigen FAM199X PF15814.5 ETS84727.1 - 6.2 5.8 10.4 10 5.0 10.4 1.4 1 0 0 1 1 1 0 Protein family FAM199X Arrestin_C PF02752.22 ETS84728.1 - 2.4e-15 57.2 0.1 1.8e-14 54.4 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ETS84728.1 - 5e-06 26.6 0.1 0.059 13.4 0.0 2.4 1 1 1 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Dehydratase_hem PF13816.6 ETS84729.1 - 5.2e-114 380.8 0.1 6e-114 380.6 0.1 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.6 ETS84729.1 - 2.3e-07 31.2 0.0 0.0099 16.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) ABM PF03992.16 ETS84729.1 - 0.00054 20.0 0.3 0.0016 18.5 0.3 1.8 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Fungal_trans PF04082.18 ETS84730.1 - 3.7e-11 42.6 1.1 3.7e-11 42.6 1.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain CN_hydrolase PF00795.22 ETS84731.1 - 1.8e-45 155.3 0.0 2.3e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.16 ETS84732.1 - 9.7e-43 146.4 36.9 9.7e-43 146.4 36.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS84732.1 - 1.7e-13 50.2 6.2 1.7e-13 50.2 6.2 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter PTR2 PF00854.21 ETS84732.1 - 0.0055 15.6 7.1 0.015 14.2 7.1 1.7 1 0 0 1 1 1 1 POT family SesA PF17107.5 ETS84733.1 - 1.5e-05 25.2 3.4 1.6e-05 25.1 0.1 2.4 2 1 1 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases HeLo PF14479.6 ETS84733.1 - 0.0043 16.9 4.8 0.044 13.6 4.2 2.4 1 1 1 2 2 2 1 Prion-inhibition and propagation Helo_like_N PF17111.5 ETS84733.1 - 0.0051 16.2 5.1 0.0067 15.8 0.7 2.2 1 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Ead_Ea22 PF13935.6 ETS84733.1 - 0.016 15.9 0.7 0.9 10.2 0.1 2.4 1 1 0 2 2 2 0 Ead/Ea22-like protein DUF1664 PF07889.12 ETS84733.1 - 0.092 12.8 2.9 0.25 11.4 0.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HSCB_C PF07743.13 ETS84733.1 - 1.6 9.3 4.1 1.2 9.6 0.1 2.8 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Glyco_hydro_32N PF00251.20 ETS84734.1 - 1.3e-14 54.4 0.1 1.9e-13 50.7 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 ETS84734.1 - 4.5e-14 52.7 0.3 7.4e-14 52.0 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Abhydrolase_1 PF00561.20 ETS84735.1 - 1.3e-19 70.8 0.8 4.7e-19 69.0 0.8 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS84735.1 - 3.2e-17 62.6 0.0 7.7e-17 61.4 0.0 1.7 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS84735.1 - 8.7e-15 55.9 2.3 1.5e-14 55.2 2.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 ETS84735.1 - 3e-05 22.9 0.0 4.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family PGAP1 PF07819.13 ETS84735.1 - 0.0012 18.6 0.1 0.0023 17.7 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF1057 PF06342.12 ETS84735.1 - 0.0041 16.2 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_5 PF12695.7 ETS84735.1 - 0.0096 15.7 0.0 0.052 13.3 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 ETS84735.1 - 0.038 13.8 0.1 0.25 11.2 0.0 2.2 2 1 0 2 2 2 0 alpha/beta hydrolase fold PE-PPE PF08237.11 ETS84735.1 - 0.048 13.2 0.0 0.08 12.5 0.0 1.5 1 1 0 1 1 1 0 PE-PPE domain Esterase PF00756.20 ETS84735.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Ser_hydrolase PF06821.13 ETS84735.1 - 0.074 12.9 0.0 0.67 9.8 0.0 2.1 1 1 1 2 2 2 0 Serine hydrolase Thioesterase PF00975.20 ETS84735.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Eno-Rase_NADH_b PF12242.8 ETS84735.1 - 0.17 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AAA PF00004.29 ETS84738.1 - 2.3e-17 63.6 0.0 4.8e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ETS84738.1 - 0.00022 21.3 0.0 0.00049 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ETS84738.1 - 0.00093 19.5 0.1 0.0034 17.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS84738.1 - 0.0012 19.2 0.0 0.0049 17.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ETS84738.1 - 0.053 14.1 0.3 0.21 12.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ETS84738.1 - 0.055 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ETS84738.1 - 0.079 12.9 1.4 0.45 10.4 0.1 2.5 2 1 1 3 3 3 0 NACHT domain AAA_14 PF13173.6 ETS84738.1 - 0.086 12.9 0.0 0.77 9.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 ETS84738.1 - 0.093 12.9 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ETS84738.1 - 0.13 11.8 0.1 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Goodbye PF17109.5 ETS84739.1 - 0.051 14.0 0.0 0.44 11.0 0.0 2.3 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain PsbH PF00737.20 ETS84740.1 - 0.01 15.5 2.1 0.45 10.3 2.1 2.4 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein PTR2 PF00854.21 ETS84741.1 - 4.6e-45 154.1 0.2 6.1e-45 153.7 0.2 1.1 1 0 0 1 1 1 1 POT family Steroid_dh PF02544.16 ETS84742.1 - 6.4e-22 78.2 1.4 6.4e-22 78.2 1.4 2.4 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 ETS84742.1 - 2.6e-05 23.9 2.2 4.3e-05 23.1 2.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) MINDY_DUB PF04424.13 ETS84743.1 - 6.2e-25 87.5 0.0 9.6e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase COesterase PF00135.28 ETS84744.1 - 4.1e-92 309.7 0.0 5.3e-92 309.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS84744.1 - 0.00011 22.1 0.1 0.00076 19.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lactamase_B PF00753.27 ETS84745.1 - 7.1e-22 78.4 2.3 1e-21 77.9 2.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS84745.1 - 3.4e-09 36.5 0.0 4.7e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DEC-1_C PF04626.13 ETS84745.1 - 0.048 14.1 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 Dec-1 protein, C terminal region Lactamase_B_3 PF13483.6 ETS84745.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Aa_trans PF01490.18 ETS84746.1 - 8.6e-42 143.3 40.1 1.1e-41 143.0 40.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HET PF06985.11 ETS84747.1 - 2.7e-31 108.9 0.1 4.1e-31 108.3 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Isochorismatase PF00857.20 ETS84749.1 - 1.2e-15 58.1 0.0 2.1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family PIF1 PF05970.14 ETS84750.1 - 1.9e-35 122.7 0.1 4.7e-24 85.2 0.0 3.4 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 ETS84750.1 - 1.8e-22 80.0 0.0 1.7e-19 70.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 ETS84750.1 - 2.3e-10 41.0 0.0 9.2e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 ETS84750.1 - 5.5e-07 27.9 0.1 1.4e-05 23.2 0.0 2.6 3 0 0 3 3 3 1 Helicase Viral_helicase1 PF01443.18 ETS84750.1 - 1.1e-06 28.6 2.9 0.09 12.5 0.4 3.7 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 ETS84750.1 - 4.3e-05 23.3 0.0 0.00012 21.8 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain MeaB PF03308.16 ETS84750.1 - 0.00017 20.7 0.0 0.00028 19.9 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 ETS84750.1 - 0.00026 21.0 0.1 0.0013 18.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ETS84750.1 - 0.0011 19.3 0.0 0.0027 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ETS84750.1 - 0.0019 18.3 0.2 0.0091 16.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 ETS84750.1 - 0.0022 17.9 0.3 0.2 11.5 0.1 2.3 2 0 0 2 2 2 1 NTPase AAA PF00004.29 ETS84750.1 - 0.0048 17.3 0.0 0.0088 16.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 ETS84750.1 - 0.0076 16.8 0.0 0.019 15.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter APS_kinase PF01583.20 ETS84750.1 - 0.0094 15.9 0.1 0.021 14.8 0.1 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.6 ETS84750.1 - 0.015 15.6 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 ETS84750.1 - 0.027 14.2 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 ETS84750.1 - 0.028 14.2 0.2 0.099 12.4 0.0 1.8 1 1 1 2 2 2 0 DEAD/DEAH box helicase ISPD_C PF18706.1 ETS84750.1 - 0.033 13.8 0.1 0.057 13.1 0.1 1.3 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain TrwB_AAD_bind PF10412.9 ETS84750.1 - 0.057 12.3 0.1 0.1 11.5 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 ETS84750.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 ETS84750.1 - 0.075 12.2 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 ETS84750.1 - 0.085 12.8 0.4 0.42 10.5 0.4 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 ETS84750.1 - 0.087 13.2 0.3 0.6 10.5 0.3 2.4 1 1 0 1 1 1 0 RNA helicase PhoH PF02562.16 ETS84750.1 - 0.093 12.2 0.0 0.96 8.9 0.0 2.4 2 1 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 ETS84750.1 - 0.096 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 ETS84750.1 - 0.1 12.3 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 ETS84750.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Helicase_RecD PF05127.14 ETS84750.1 - 0.15 11.9 0.3 0.5 10.2 0.3 1.8 1 1 0 1 1 1 0 Helicase Rad17 PF03215.15 ETS84750.1 - 0.28 11.1 1.1 0.4 10.6 0.1 1.6 2 0 0 2 2 1 0 Rad17 P-loop domain c-SKI_SMAD_bind PF08782.10 ETS84750.1 - 4.9 7.5 10.4 8.3 6.7 3.1 2.8 3 0 0 3 3 2 0 c-SKI Smad4 binding domain AMP-binding PF00501.28 ETS84751.1 - 8.3e-87 291.5 0.0 1.1e-86 291.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme SSV1_ORF_D-335 PF07935.11 ETS84752.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 ORF D-335-like protein 2OG-FeII_Oxy_3 PF13640.6 ETS84754.1 - 2.6e-08 34.6 0.0 6.8e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HET PF06985.11 ETS84755.1 - 4.3e-22 79.0 0.2 7e-18 65.4 0.4 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) NDUFA12 PF05071.16 ETS84757.1 - 3.3e-11 43.9 0.2 3.3e-11 43.9 0.2 2.1 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 CH PF00307.31 ETS84758.1 - 7.4e-12 45.4 0.0 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF1720 PF08226.11 ETS84758.1 - 0.08 13.4 9.7 0.072 13.5 1.7 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1720) DUF4451 PF14616.6 ETS84760.1 - 6.3e-24 84.5 0.1 1.2e-23 83.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) F-box-like PF12937.7 ETS84762.1 - 0.0031 17.4 2.0 0.022 14.7 0.5 2.6 1 1 1 2 2 2 1 F-box-like LRR_4 PF12799.7 ETS84762.1 - 0.047 14.1 20.3 0.23 12.0 0.7 6.7 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ETS84762.1 - 4.5 7.1 12.7 9.9 6.0 0.0 4.7 5 1 1 6 6 6 0 Leucine rich repeat Rad9 PF04139.13 ETS84763.1 - 5e-48 163.7 0.5 6e-48 163.5 0.5 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 ETS84763.1 - 0.0022 17.1 1.9 0.021 13.9 1.9 2.5 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 ETS84763.1 - 0.086 11.9 0.0 0.31 10.1 0.0 1.8 2 0 0 2 2 2 0 Hus1-like protein RCC1 PF00415.18 ETS84764.1 - 1.3e-38 131.4 18.0 4e-10 40.2 0.1 7.4 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ETS84764.1 - 1.5e-20 72.4 36.3 6.7e-07 29.0 0.7 6.7 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat PDH PF02153.17 ETS84765.1 - 4.7e-16 58.6 0.0 6.8e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 ETS84765.1 - 6.9e-07 29.6 0.0 1.4e-06 28.5 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ETS84765.1 - 9.8e-06 26.1 0.1 5.1e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 ETS84765.1 - 1.9e-05 24.4 0.0 4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 ETS84765.1 - 8.8e-05 21.9 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ETS84765.1 - 0.0054 16.6 0.0 0.0094 15.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 ETS84765.1 - 0.018 14.6 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 ETS84765.1 - 0.084 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Carb_anhydrase PF00194.21 ETS84766.1 - 6.2e-29 101.3 0.0 1e-26 94.0 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF2205 PF10224.9 ETS84766.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Short coiled-coil protein Ribosomal_L24e PF01246.20 ETS84767.1 - 1.3e-27 95.8 0.2 1.3e-27 95.8 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e A_deamin PF02137.18 ETS84768.1 - 5.7e-31 108.2 0.0 1.5e-18 67.3 0.0 2.1 1 1 1 2 2 2 2 Adenosine-deaminase (editase) domain Chorion_2 PF03964.15 ETS84768.1 - 6.4 7.7 10.6 1.9 9.4 2.9 2.5 2 0 0 2 2 2 0 Chorion family 2 NAC PF01849.18 ETS84769.1 - 1.2e-22 79.6 0.1 2e-22 78.9 0.1 1.4 1 0 0 1 1 1 1 NAC domain RdRP PF05183.12 ETS84770.1 - 2.1e-183 611.2 0.0 2.8e-183 610.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 ETS84770.1 - 0.0069 16.2 0.0 0.024 14.5 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD-oxidase_C PF02913.19 ETS84771.1 - 1e-61 208.7 0.1 2e-61 207.8 0.0 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ETS84771.1 - 1.9e-35 121.6 0.0 4.6e-35 120.4 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 ETS84771.1 - 0.088 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Ribosomal_S4e PF00900.20 ETS84772.1 - 1.1e-36 124.5 0.2 2.4e-36 123.4 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 ETS84772.1 - 1.6e-24 85.2 0.1 2.9e-24 84.4 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 ETS84772.1 - 1.5e-18 66.6 5.7 2.9e-18 65.7 5.7 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.29 ETS84772.1 - 0.00016 21.5 6.7 0.00016 21.5 6.7 3.0 4 0 0 4 4 4 1 KOW motif S4 PF01479.25 ETS84772.1 - 0.00026 20.6 0.0 0.0005 19.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain Myb_DNA-binding PF00249.31 ETS84773.1 - 2.3e-17 62.9 0.5 1.8e-08 34.4 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ETS84773.1 - 4.5e-12 46.0 0.7 4.3e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 ETS84773.1 - 1.1e-06 28.6 0.4 0.043 13.8 0.0 2.5 2 0 0 2 2 2 2 SLIDE CHDCT2 PF08074.11 ETS84773.1 - 0.0044 17.2 0.4 0.017 15.3 0.3 2.0 2 1 0 2 2 2 1 CHDCT2 (NUC038) domain SANT_DAMP1_like PF16282.5 ETS84773.1 - 0.0077 16.4 0.0 0.02 15.1 0.0 1.6 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 bZIP_1 PF00170.21 ETS84775.1 - 2.2e-10 40.5 13.1 3.8e-10 39.7 13.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 ETS84775.1 - 2.2e-07 30.9 0.0 2.2e-07 30.9 0.0 2.4 1 1 1 2 2 2 1 Transcription factor PAP1 SHE3 PF17078.5 ETS84775.1 - 0.0016 18.2 5.2 0.0024 17.6 5.2 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 V_ATPase_I PF01496.19 ETS84775.1 - 0.0026 15.8 1.6 0.0031 15.5 1.6 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Takusan PF04822.13 ETS84775.1 - 0.0084 16.0 0.1 0.02 14.8 0.1 1.7 1 0 0 1 1 1 1 Takusan DUF966 PF06136.13 ETS84775.1 - 0.015 15.0 8.2 0.017 14.8 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DivIC PF04977.15 ETS84775.1 - 0.017 14.9 4.0 0.041 13.7 4.0 1.6 1 0 0 1 1 1 0 Septum formation initiator GIT_CC PF16559.5 ETS84775.1 - 0.02 14.8 2.6 0.035 14.0 2.6 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 ETS84775.1 - 0.041 14.5 0.2 0.087 13.5 0.2 1.6 1 0 0 1 1 1 0 Initiation control protein YabA bZIP_2 PF07716.15 ETS84775.1 - 0.074 13.1 18.2 0.22 11.6 16.0 2.2 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 ETS84775.1 - 0.08 13.5 14.7 0.066 13.7 13.1 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor TFIIA PF03153.13 ETS84775.1 - 0.082 12.9 13.6 0.092 12.7 13.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LMSTEN PF07988.12 ETS84775.1 - 0.12 11.9 1.3 16 5.1 0.0 2.5 2 0 0 2 2 2 0 LMSTEN motif Atg14 PF10186.9 ETS84775.1 - 0.31 10.1 6.7 0.46 9.5 6.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 ETS84775.1 - 0.44 10.6 10.3 0.83 9.7 10.3 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SWI-SNF_Ssr4 PF08549.10 ETS84775.1 - 0.96 8.0 16.8 1.2 7.7 16.8 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF812 PF05667.11 ETS84775.1 - 2.7 6.8 13.7 3.9 6.3 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF1151 PF06625.11 ETS84778.1 - 0.027 14.4 4.9 0.036 14.0 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) FTR1 PF03239.14 ETS84778.1 - 0.037 13.2 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family LapA_dom PF06305.11 ETS84778.1 - 0.39 10.6 1.6 18 5.2 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF945 PF06097.11 ETS84778.1 - 0.42 9.7 4.6 0.24 10.5 0.2 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF945) DUF4692 PF15763.5 ETS84779.1 - 0.38 11.2 3.3 0.53 10.7 3.3 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) His_Phos_1 PF00300.22 ETS84780.1 - 2.7e-35 121.8 5.5 1.3e-32 113.0 5.5 2.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Zn_clus PF00172.18 ETS84782.1 - 3.4e-08 33.5 7.6 5e-08 32.9 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.6 ETS84783.1 - 4.1e-13 49.5 0.0 6.9e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS84783.1 - 1e-10 42.2 0.0 2.4e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS84783.1 - 4.7e-10 40.0 0.3 3.9e-09 37.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS84783.1 - 6.8e-10 39.5 0.0 2.7e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS84783.1 - 2.6e-08 33.8 0.0 5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS84783.1 - 9.9e-05 21.8 0.0 0.00029 20.2 0.0 1.7 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 ETS84783.1 - 0.0065 16.5 0.0 0.018 15.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DUF5012 PF16404.5 ETS84783.1 - 0.084 13.0 0.0 9.9 6.3 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5012) CMAS PF02353.20 ETS84783.1 - 0.15 11.3 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase NOA36 PF06524.12 ETS84783.1 - 4.9 6.4 10.1 7.4 5.8 10.1 1.2 1 0 0 1 1 1 0 NOA36 protein GAT PF03127.14 ETS84784.1 - 1.2e-16 60.7 0.4 1.2e-16 60.7 0.4 2.0 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 ETS84784.1 - 3.3e-05 23.8 0.0 8.6e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 VHS domain DUF3486 PF11985.8 ETS84784.1 - 0.12 12.7 0.2 0.26 11.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) MFS_1 PF07690.16 ETS84785.1 - 4.4e-23 81.8 30.3 1.9e-12 46.8 3.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS84785.1 - 6.4e-07 28.3 22.6 2.2e-05 23.2 6.1 3.4 2 2 2 4 4 4 4 MFS/sugar transport protein Sugar_tr PF00083.24 ETS84785.1 - 0.0001 21.3 10.6 0.0062 15.4 3.9 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 ETS84785.1 - 0.015 14.2 20.2 0.035 13.0 5.5 2.7 1 1 0 2 2 2 0 MFS_1 like family CorA PF01544.18 ETS84786.1 - 3.9e-06 26.4 1.0 7.7e-06 25.4 1.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Acyl_transf_3 PF01757.22 ETS84787.1 - 9.6e-23 80.8 21.6 9.6e-23 80.8 21.6 1.6 2 0 0 2 2 2 1 Acyltransferase family SET PF00856.28 ETS84788.1 - 1.7e-15 57.8 0.5 1.7e-15 57.8 0.5 2.9 3 1 0 3 3 3 1 SET domain AWS PF17907.1 ETS84788.1 - 3.5e-07 30.2 6.5 6.8e-07 29.2 6.5 1.5 1 0 0 1 1 1 1 AWS domain dCMP_cyt_deam_1 PF00383.23 ETS84789.1 - 2.4e-20 72.3 0.0 6.1e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ETS84789.1 - 2.8e-17 62.7 0.1 1.7e-07 31.0 0.0 2.6 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 ETS84789.1 - 0.002 18.2 1.1 0.025 14.7 1.1 2.5 1 1 0 1 1 1 1 Bd3614-like deaminase Inv-AAD PF18785.1 ETS84789.1 - 0.085 12.7 0.0 6.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Invertebrate-AID/APOBEC-deaminase Zn_clus PF00172.18 ETS84790.1 - 1.2 9.3 9.7 2 8.6 9.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sina PF03145.16 ETS84791.1 - 0.015 15.3 0.1 0.032 14.2 0.1 1.5 1 0 0 1 1 1 0 Seven in absentia protein family PHF5 PF03660.14 ETS84791.1 - 0.19 11.9 3.0 1.5 9.0 0.1 2.2 2 0 0 2 2 2 0 PHF5-like protein DUF2439 PF10382.9 ETS84792.1 - 6.2e-24 84.1 0.1 1.2e-23 83.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) BAR PF03114.18 ETS84793.1 - 1.3e-16 60.9 0.3 2.7e-16 59.9 0.2 1.4 2 0 0 2 2 2 1 BAR domain SH3_1 PF00018.28 ETS84793.1 - 2.2e-13 49.6 0.3 5.1e-13 48.4 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 ETS84793.1 - 2.4e-11 43.3 0.0 4.5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ETS84793.1 - 1.5e-08 34.2 0.0 3.1e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain MARVEL PF01284.23 ETS84795.1 - 5.6e-06 26.4 12.8 6.4e-05 23.0 9.3 2.2 2 0 0 2 2 2 2 Membrane-associating domain Promethin PF16015.5 ETS84795.1 - 0.00039 20.3 4.4 0.065 13.2 0.1 2.2 1 1 1 2 2 2 2 Promethin VIT1 PF01988.19 ETS84795.1 - 0.6 9.9 6.2 0.21 11.4 3.6 1.5 1 1 1 2 2 2 0 VIT family Response_reg PF00072.24 ETS84796.1 - 6.4e-20 71.4 0.0 7.4e-14 51.9 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain Bot1p PF12298.8 ETS84797.1 - 2.8e-48 164.4 1.1 2.8e-48 164.4 1.1 1.7 1 1 1 2 2 2 1 Eukaryotic mitochondrial regulator protein Y_phosphatase3 PF13350.6 ETS84798.1 - 7.6e-57 192.9 0.0 9e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ETS84798.1 - 0.00073 19.2 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 ETS84798.1 - 0.0073 15.9 0.0 0.019 14.5 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.14 ETS84798.1 - 0.1 11.5 0.1 0.22 10.4 0.0 1.7 2 1 0 2 2 2 0 Myotubularin-like phosphatase domain LSM PF01423.22 ETS84800.1 - 1.8e-18 66.0 0.1 2.3e-18 65.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain Zn_clus PF00172.18 ETS84801.1 - 0.017 15.2 10.7 0.031 14.4 10.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pan3_PK PF18101.1 ETS84802.1 - 1e-60 203.7 0.2 1.6e-60 203.1 0.2 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 ETS84802.1 - 4.9e-05 22.8 0.0 8.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain X8 PF07983.13 ETS84802.1 - 0.049 14.3 0.1 0.15 12.8 0.1 1.8 1 0 0 1 1 1 0 X8 domain UBA_4 PF14555.6 ETS84803.1 - 1.9e-10 40.4 0.0 4.1e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 ETS84803.1 - 0.00013 22.1 0.0 0.00027 21.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain WPP PF13943.6 ETS84803.1 - 0.027 14.9 0.6 0.027 14.9 0.6 2.9 2 1 1 3 3 3 0 WPP domain SUB1_ProdP9 PF18213.1 ETS84803.1 - 0.061 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 DUF1682 PF07946.14 ETS84803.1 - 0.17 11.0 8.6 0.31 10.2 8.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PRP21_like_P PF12230.8 ETS84804.1 - 5.2e-55 186.7 7.6 3e-54 184.2 7.6 2.1 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 ETS84804.1 - 5.6e-41 138.3 1.7 1.8e-20 72.7 0.0 2.6 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 ETS84804.1 - 0.042 13.4 0.1 0.099 12.3 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger PMT PF02366.18 ETS84805.1 - 2e-79 266.6 15.9 2e-79 266.6 15.9 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ETS84805.1 - 3e-66 222.8 7.5 3e-66 222.8 7.5 2.3 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ETS84805.1 - 1.1e-46 159.0 0.0 2.2e-46 158.0 0.0 1.5 1 0 0 1 1 1 1 MIR domain Pkinase PF00069.25 ETS84806.1 - 1.6e-53 181.8 0.0 2.2e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS84806.1 - 7.5e-25 87.7 0.5 7.6e-24 84.4 0.5 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ETS84806.1 - 0.077 11.8 0.0 0.16 10.7 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 ETS84806.1 - 0.17 11.5 0.9 18 4.9 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 BNR PF02012.20 ETS84807.1 - 0.0002 20.9 0.9 1.1 9.5 0.0 3.6 2 0 0 2 2 2 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 ETS84807.1 - 0.051 12.4 0.0 1.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, Abhydrolase_6 PF12697.7 ETS84808.1 - 4.5e-12 47.0 0.0 6.5e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS84808.1 - 0.00051 19.4 0.0 0.00087 18.6 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS84808.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ank_2 PF12796.7 ETS84809.1 - 1.3e-25 89.8 9.9 6.1e-09 36.3 0.4 5.5 4 2 3 7 7 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS84809.1 - 1.5e-21 76.4 7.7 1.5e-07 31.9 0.1 5.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS84809.1 - 4.2e-15 54.4 5.0 0.98 10.2 0.0 8.7 8 0 0 8 8 7 4 Ankyrin repeat Ank PF00023.30 ETS84809.1 - 6.1e-14 51.7 8.3 0.11 13.0 0.0 7.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 ETS84809.1 - 3.7e-08 33.5 8.2 0.019 15.3 0.0 6.5 5 2 2 7 7 7 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 ETS84809.1 - 4.6e-06 27.1 0.0 1.5e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NACHT_N PF17100.5 ETS84809.1 - 1e-05 25.5 0.2 2.4e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 ETS84809.1 - 6.3e-05 23.0 0.1 0.00015 21.7 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ETS84809.1 - 7.5e-05 23.0 0.0 0.00063 20.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain Filo_VP24 PF06389.11 ETS84809.1 - 0.023 14.2 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Filovirus membrane-associated protein VP24 NB-ARC PF00931.22 ETS84809.1 - 0.071 12.3 0.1 1.2 8.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 ETS84809.1 - 0.11 13.1 0.0 1.2 9.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain Fungal_trans PF04082.18 ETS84810.1 - 5.7e-14 51.8 0.3 1.5e-13 50.5 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cupin_1 PF00190.22 ETS84811.1 - 6.1e-08 32.4 0.0 8.7e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 ETS84811.1 - 8.8e-07 28.6 1.1 5.2e-06 26.1 1.1 2.1 1 1 0 1 1 1 1 Cupin domain GMC_oxred_C PF05199.13 ETS84811.1 - 0.0067 17.0 0.0 0.0093 16.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Cupin_3 PF05899.12 ETS84811.1 - 0.052 13.2 0.2 0.13 12.0 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF861) AA_permease PF00324.21 ETS84812.1 - 1.6e-67 228.2 43.6 2e-67 227.9 43.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS84812.1 - 5.7e-25 88.0 50.4 7.6e-25 87.6 50.4 1.0 1 0 0 1 1 1 1 Amino acid permease FMO-like PF00743.19 ETS84813.1 - 3.2e-12 45.7 0.0 9.2e-12 44.1 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ETS84813.1 - 6.4e-11 42.0 0.0 9.3e-08 31.6 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS84813.1 - 2e-10 40.7 0.0 7.9e-09 35.6 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS84813.1 - 9.8e-07 28.3 0.0 3.2e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS84813.1 - 7.7e-06 25.3 0.4 6.8e-05 22.2 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ETS84813.1 - 7.4e-05 22.8 0.1 0.2 11.6 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 ETS84813.1 - 0.0049 16.2 0.0 0.0085 15.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 ETS84813.1 - 0.017 15.7 0.0 6 7.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ETS84813.1 - 0.048 13.7 0.0 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Agglutinin PF07468.11 ETS84814.1 - 0.096 12.9 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Agglutinin domain Ank_2 PF12796.7 ETS84815.1 - 7.6e-24 84.1 0.2 1.2e-11 45.0 0.0 4.1 4 1 0 4 4 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS84815.1 - 4.5e-19 68.5 0.1 3.2e-07 30.8 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS84815.1 - 1.5e-13 49.6 0.1 0.26 11.9 0.0 7.5 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 ETS84815.1 - 1.7e-13 50.5 0.1 7.4e-05 23.0 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS84815.1 - 2.6e-13 49.8 0.0 0.028 14.9 0.0 6.2 6 0 0 6 6 5 3 Ankyrin repeat NACHT PF05729.12 ETS84815.1 - 2.4e-08 34.1 0.0 5.9e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS84815.1 - 7.8e-08 32.9 0.0 3.4e-07 30.8 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS84815.1 - 4.5e-05 23.7 0.0 0.00018 21.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain SesA PF17107.5 ETS84815.1 - 0.0021 18.3 0.1 0.0055 16.9 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases HBM PF16591.5 ETS84815.1 - 0.0036 16.8 0.1 0.0069 15.8 0.1 1.4 1 0 0 1 1 1 1 Helical bimodular sensor domain TPR_12 PF13424.6 ETS84815.1 - 0.0077 16.5 0.2 0.039 14.3 0.1 2.4 2 0 0 2 2 1 1 Tetratricopeptide repeat AAA_7 PF12775.7 ETS84815.1 - 0.0081 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 ETS84815.1 - 0.01 16.3 0.0 0.027 14.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 ETS84815.1 - 0.023 14.6 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 ETS84815.1 - 0.024 13.8 0.0 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 ETS84815.1 - 0.054 13.9 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Macro PF01661.21 ETS84816.1 - 3.3e-24 85.2 0.0 5e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Macro domain Abhydrolase_3 PF07859.13 ETS84817.1 - 2.2e-13 50.6 0.0 3.5e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 ETS84817.1 - 2.3e-09 36.6 0.0 2.9e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 ETS84817.1 - 1.2e-08 34.7 0.0 0.0015 18.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 ETS84817.1 - 4.4e-08 32.5 0.0 7.7e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 ETS84817.1 - 1.9e-06 27.4 0.0 4e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 ETS84817.1 - 6.4e-06 26.0 0.0 1.2e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.11 ETS84817.1 - 2.1e-05 23.7 0.0 3.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_1 PF00561.20 ETS84817.1 - 8.1e-05 22.4 0.0 0.021 14.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 ETS84817.1 - 0.0039 15.9 0.1 0.49 9.0 0.0 2.4 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 ETS84817.1 - 0.068 12.7 0.0 0.61 9.6 0.0 2.3 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 ETS84817.1 - 0.073 12.9 0.0 0.4 10.5 0.0 2.1 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase MFS_1 PF07690.16 ETS84818.1 - 5.4e-31 107.8 24.5 5.4e-31 107.8 24.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS84818.1 - 2.1e-10 40.0 29.3 5.4e-10 38.7 11.5 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter BT1 PF03092.16 ETS84818.1 - 1.2 7.3 10.9 0.024 12.9 3.0 2.1 3 0 0 3 3 3 0 BT1 family DUF4735 PF15882.5 ETS84819.1 - 0.2 11.1 0.4 0.3 10.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) Beach PF02138.18 ETS84821.1 - 8.9e-119 395.9 0.0 1.4e-118 395.2 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 ETS84821.1 - 5.1e-12 45.8 0.0 1.5e-11 44.2 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 ETS84821.1 - 2.8e-10 40.5 0.0 6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 ETS84821.1 - 0.00017 22.3 5.2 0.38 11.7 0.1 5.4 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF4704 PF15787.5 ETS84821.1 - 0.015 14.6 0.0 0.055 12.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) DDOST_48kD PF03345.14 ETS84823.1 - 4.9e-168 559.3 0.0 5.6e-168 559.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Peptidase_S8 PF00082.22 ETS84824.1 - 8.6e-32 110.6 9.5 1.6e-31 109.7 9.5 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ETS84824.1 - 7.5e-20 71.4 1.2 1.5e-19 70.4 1.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Tropomodulin PF03250.14 ETS84825.1 - 0.17 11.9 0.2 0.47 10.5 0.2 1.7 1 0 0 1 1 1 0 Tropomodulin Peptidase_S15 PF02129.18 ETS84826.1 - 1.6e-39 136.2 1.9 5.5e-35 121.3 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ETS84826.1 - 3.1e-37 128.7 0.0 4.2e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 ETS84826.1 - 0.078 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PhyH PF05721.13 ETS84827.1 - 8.5e-07 29.4 0.0 1.6e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 ETS84827.1 - 0.0048 15.7 0.0 0.13 11.0 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 ETS84827.1 - 0.015 15.7 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Fungal_trans PF04082.18 ETS84828.1 - 2e-13 50.0 0.3 4.3e-13 48.9 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS84828.1 - 1.5e-08 34.6 9.1 2.5e-08 33.9 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ETS84829.1 - 5e-19 68.4 17.4 5e-19 68.4 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS84829.1 - 2.8e-05 23.2 16.7 2.8e-05 23.2 16.7 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter Dicty_REP PF05086.12 ETS84830.1 - 0.14 10.1 3.4 0.18 9.7 3.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AAL_decarboxy PF03306.13 ETS84830.1 - 0.15 11.4 0.0 0.15 11.4 0.0 1.5 2 0 0 2 2 2 0 Alpha-acetolactate decarboxylase SOG2 PF10428.9 ETS84830.1 - 0.21 10.7 9.3 0.25 10.5 9.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein FSA_C PF10479.9 ETS84830.1 - 1.3 7.0 9.4 1.6 6.8 9.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SR-25 PF10500.9 ETS84830.1 - 1.8 8.1 7.2 2.5 7.7 7.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PRR18 PF15671.5 ETS84830.1 - 4.4 7.1 11.1 7.4 6.4 11.1 1.3 1 0 0 1 1 1 0 Proline-rich protein family 18 MGC-24 PF05283.11 ETS84830.1 - 4.7 7.7 16.6 8.3 6.9 16.6 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ribosomal_S27e PF01667.17 ETS84831.1 - 5.6e-28 96.4 7.5 7.5e-28 96.0 7.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 ETS84831.1 - 0.23 11.0 3.7 0.35 10.4 3.7 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Phosducin PF02114.16 ETS84832.1 - 5.3e-13 48.5 0.3 8e-13 47.9 0.3 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 ETS84832.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin NPH-II PF12011.8 ETS84832.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA helicase NPH-II LRR_4 PF12799.7 ETS84833.1 - 2.4e-06 27.8 4.1 0.00012 22.4 1.3 3.2 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ETS84833.1 - 2.4e-06 27.2 6.2 0.00033 20.3 1.6 4.0 3 1 1 4 4 4 3 Leucine rich repeat 4HBT PF03061.22 ETS84834.1 - 3.8e-07 30.4 0.2 6.9e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 Thioesterase superfamily MoeA_C PF03454.15 ETS84834.1 - 0.14 12.3 0.0 0.82 9.9 0.0 2.0 2 0 0 2 2 2 0 MoeA C-terminal region (domain IV) FAD_binding_3 PF01494.19 ETS84835.1 - 2.4e-73 247.4 0.0 8.8e-73 245.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 ETS84835.1 - 2.3e-28 99.3 0.0 4.1e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 ETS84835.1 - 6e-06 26.4 0.0 3.8e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS84835.1 - 4.4e-05 22.9 0.0 6.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS84835.1 - 5.4e-05 22.1 0.0 7.9e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 ETS84835.1 - 6.1e-05 22.3 0.0 0.00012 21.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ETS84835.1 - 0.00027 20.3 0.0 0.00042 19.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS84835.1 - 0.0012 18.6 0.0 0.0026 17.4 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ETS84835.1 - 0.0015 17.9 0.0 0.0031 16.8 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 ETS84835.1 - 0.0039 16.3 0.0 0.0064 15.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 ETS84835.1 - 0.0043 16.0 0.0 0.0062 15.4 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 ETS84835.1 - 0.0049 16.2 0.0 0.008 15.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 ETS84835.1 - 0.006 16.0 0.1 0.0097 15.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS84835.1 - 0.028 15.0 0.0 0.064 13.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ETS84835.1 - 0.039 14.2 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Glu_dehyd_C PF16912.5 ETS84835.1 - 0.042 13.3 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus GIDA PF01134.22 ETS84835.1 - 0.05 12.7 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.10 ETS84835.1 - 0.15 11.1 0.0 0.37 9.8 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase FTR PF01913.18 ETS84835.1 - 0.16 11.9 0.1 0.37 10.7 0.1 1.5 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Acetyltransf_7 PF13508.7 ETS84836.1 - 0.00028 21.2 0.0 0.001 19.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Ank_5 PF13857.6 ETS84836.1 - 0.012 16.0 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Acetyltransf_CG PF14542.6 ETS84836.1 - 0.023 14.8 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Ank PF00023.30 ETS84836.1 - 0.036 14.5 0.0 0.093 13.2 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.6 ETS84836.1 - 0.049 14.2 0.0 0.17 12.6 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 ETS84836.1 - 0.14 12.8 0.0 0.31 11.7 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) RRN3 PF05327.11 ETS84836.1 - 0.24 9.9 11.4 0.48 8.9 11.4 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 ETS84836.1 - 0.39 9.0 8.9 0.59 8.4 8.9 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 ETS84836.1 - 0.39 10.0 21.5 0.75 9.1 21.5 1.4 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 ETS84836.1 - 0.77 7.8 24.8 1.2 7.1 24.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 ETS84836.1 - 0.78 9.4 4.2 2.4 7.8 4.2 1.9 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 ETS84836.1 - 1 7.5 17.4 1.4 7.0 17.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 ETS84836.1 - 1 8.7 14.2 1.6 8.1 14.2 1.2 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.11 ETS84836.1 - 1.3 9.1 8.1 2.9 7.9 8.1 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal RNA_pol_3_Rpc31 PF11705.8 ETS84836.1 - 6.3 7.0 22.8 13 5.9 22.8 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sigma70_ner PF04546.13 ETS84836.1 - 8.7 6.2 11.3 17 5.2 11.3 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3435 PF11917.8 ETS84837.1 - 1.8e-08 33.8 0.0 3.6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) UPF0688 PF15772.5 ETS84837.1 - 0.02 15.2 0.1 0.037 14.3 0.1 1.4 1 0 0 1 1 1 0 UPF0688 family PLDc_2 PF13091.6 ETS84838.1 - 5.2e-25 87.9 0.0 3.7e-13 49.5 0.1 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 ETS84838.1 - 0.0011 19.1 0.5 1.4 9.2 0.1 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif FAM83 PF07894.12 ETS84838.1 - 0.64 9.5 4.4 1.3 8.5 0.0 3.0 3 0 0 3 3 3 0 FAM83 A-H YABBY PF04690.13 ETS84842.1 - 0.39 11.3 3.4 1.4 9.4 0.0 2.1 1 1 1 2 2 2 0 YABBY protein EST1_DNA_bind PF10373.9 ETS84843.1 - 3.8e-13 49.6 0.2 7.3e-09 35.5 0.0 3.1 3 0 0 3 3 3 2 Est1 DNA/RNA binding domain Putative_PNPOx PF01243.20 ETS84844.1 - 7.2e-09 35.7 0.0 1.2e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RTC PF01137.21 ETS84845.1 - 3.9e-49 166.8 0.0 6e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Phosphodiest PF01663.22 ETS84846.1 - 1.7e-91 307.5 0.7 2.4e-91 307.0 0.7 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ETS84846.1 - 0.0044 16.5 0.2 0.12 11.8 0.0 2.3 1 1 0 2 2 2 2 Sulfatase RNR_inhib PF08591.10 ETS84847.1 - 5.3e-30 104.9 0.1 1.1e-29 103.9 0.1 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor SIP1 PF04938.12 ETS84848.1 - 4e-08 33.3 0.0 0.014 15.1 0.0 3.3 3 0 0 3 3 3 3 Survival motor neuron (SMN) interacting protein 1 (SIP1) ZIP4_domain PF18292.1 ETS84849.1 - 0.15 12.0 0.1 0.19 11.6 0.1 1.1 1 0 0 1 1 1 0 Zinc transporter ZIP4 domain Pyridoxal_deC PF00282.19 ETS84850.1 - 7.1e-22 77.6 0.1 5.2e-14 51.8 0.0 3.0 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain EzrA PF06160.12 ETS84850.1 - 0.0091 14.2 0.6 0.013 13.7 0.6 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA LisH PF08513.11 ETS84851.1 - 0.089 12.8 0.3 13 5.9 0.0 3.3 3 0 0 3 3 3 0 LisH Transposase_1 PF01359.18 ETS84851.1 - 0.22 11.4 0.8 0.68 9.8 0.0 2.2 3 0 0 3 3 3 0 Transposase (partial DDE domain) AAA PF00004.29 ETS84852.1 - 1.7e-16 60.8 0.0 7e-16 58.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS84852.1 - 0.00064 20.0 1.2 0.02 15.1 0.1 2.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS84852.1 - 0.0036 17.7 0.0 0.012 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Torsin PF06309.11 ETS84852.1 - 0.0083 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_5 PF07728.14 ETS84852.1 - 0.022 14.7 0.0 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 ETS84852.1 - 0.023 14.4 0.0 0.073 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ETS84852.1 - 0.043 14.2 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ETS84852.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 ETS84852.1 - 0.09 12.9 0.1 0.68 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain adh_short PF00106.25 ETS84853.1 - 1.4e-30 106.2 0.6 5.6e-30 104.3 0.6 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS84853.1 - 1.3e-19 70.7 0.1 3.3e-19 69.4 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS84853.1 - 0.00098 19.1 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 KR domain SSF PF00474.17 ETS84854.1 - 6.3e-12 45.1 31.2 2.2e-11 43.3 31.2 1.8 1 1 0 1 1 1 1 Sodium:solute symporter family MBA1 PF07961.11 ETS84856.1 - 9.8e-10 37.9 0.0 1.3e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.15 ETS84856.1 - 0.0011 19.1 0.2 0.0017 18.4 0.2 1.3 1 0 0 1 1 1 1 Tim44-like domain SUI1 PF01253.22 ETS84857.1 - 4.1e-28 97.7 3.2 5.4e-28 97.3 3.2 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 AdoMet_MTase PF07757.13 ETS84858.1 - 2.3e-39 134.2 0.0 4.7e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 ETS84858.1 - 0.0066 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ETS84858.1 - 0.014 15.4 0.2 0.16 12.0 0.2 2.2 1 1 0 1 1 1 0 Methyltransferase domain Adaptin_N PF01602.20 ETS84859.1 - 2.2e-116 389.5 2.3 2.9e-116 389.1 2.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 ETS84859.1 - 3.1e-55 186.5 4.3 7.7e-55 185.2 4.3 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 ETS84859.1 - 1.7e-34 118.4 0.1 5.2e-34 116.8 0.1 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 ETS84859.1 - 1.9e-18 66.6 0.5 2.8e-12 46.9 0.0 5.4 2 1 3 5 5 5 1 HEAT repeats Cnd1 PF12717.7 ETS84859.1 - 1e-07 32.1 8.6 0.017 15.2 0.3 5.0 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 ETS84859.1 - 0.0016 18.9 0.8 5.6 7.9 0.0 4.4 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat CLASP_N PF12348.8 ETS84859.1 - 0.02 14.5 0.2 0.02 14.5 0.2 3.1 4 0 0 4 4 4 0 CLASP N terminal HEAT PF02985.22 ETS84859.1 - 0.031 14.5 8.2 2.1 8.8 0.3 5.7 6 0 0 6 6 6 0 HEAT repeat Alpha_adaptin_C PF02296.16 ETS84859.1 - 0.1 12.8 0.1 0.71 10.1 0.0 2.4 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain DUF5010 PF16402.5 ETS84859.1 - 0.13 11.1 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) CDP-OH_P_transf PF01066.21 ETS84860.1 - 1.2e-16 61.2 0.0 1.2e-16 61.2 0.0 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3592 PF12158.8 ETS84860.1 - 1.3 9.1 3.9 0.82 9.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) DUF3437 PF11919.8 ETS84861.1 - 0.076 12.9 0.1 0.1 12.5 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3437) SUR7 PF06687.12 ETS84862.1 - 5.6e-22 78.4 12.1 8.1e-22 77.9 12.1 1.2 1 0 0 1 1 1 1 SUR7/PalI family MARVEL PF01284.23 ETS84862.1 - 0.0071 16.4 5.3 0.0071 16.4 5.3 1.7 2 0 0 2 2 2 1 Membrane-associating domain MSP1a PF11670.8 ETS84862.1 - 0.053 12.8 0.2 0.15 11.3 0.2 1.8 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Vac7 PF12751.7 ETS84862.1 - 0.15 11.5 2.8 0.083 12.3 0.8 1.5 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 Sacchrp_dh_NADP PF03435.18 ETS84863.1 - 3.4e-19 69.4 0.2 6e-19 68.6 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 ETS84863.1 - 0.046 14.2 0.0 0.13 12.8 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ETS84863.1 - 0.086 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase P22_AR_N PF10547.9 ETS84863.1 - 0.12 12.7 0.1 0.27 11.6 0.1 1.5 1 0 0 1 1 1 0 P22_AR N-terminal domain ABC1 PF03109.16 ETS84864.1 - 1e-22 80.6 0.0 2.4e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 ETS84864.1 - 0.00082 19.4 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Septin PF00735.18 ETS84865.1 - 9.4e-35 120.2 0.2 2.2e-11 43.6 0.0 3.1 2 1 1 3 3 3 3 Septin AAA_23 PF13476.6 ETS84865.1 - 0.013 16.0 0.3 0.024 15.1 0.3 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ETS84865.1 - 0.017 15.5 0.0 0.057 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.20 ETS84865.1 - 0.018 14.2 0.0 0.04 13.1 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit AAA_18 PF13238.6 ETS84865.1 - 0.019 15.5 0.0 0.12 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 ETS84865.1 - 0.022 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family KAP_NTPase PF07693.14 ETS84865.1 - 0.028 13.7 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain Pox_A32 PF04665.12 ETS84865.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_28 PF13521.6 ETS84865.1 - 0.073 13.3 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 ETS84865.1 - 0.2 11.8 0.0 0.46 10.7 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase CDC45 PF02724.14 ETS84865.1 - 0.44 8.8 2.2 0.72 8.1 2.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 ETS84865.1 - 0.71 8.0 6.1 0.95 7.6 6.1 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L21e PF01157.18 ETS84866.1 - 1.7e-46 156.2 3.7 1.7e-46 156.2 3.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e S4 PF01479.25 ETS84867.1 - 2.3e-12 46.4 0.9 2.3e-12 46.4 0.9 2.6 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 ETS84867.1 - 8.8e-06 26.5 0.1 1.8e-05 25.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Uds1 PF15456.6 ETS84867.1 - 0.073 13.2 0.5 2.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Slu7 PF11708.8 ETS84868.1 - 1.6e-75 254.3 21.3 1.6e-75 254.3 21.3 2.5 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 ETS84868.1 - 0.03 14.0 0.4 0.055 13.2 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 ETS84868.1 - 0.039 14.0 1.2 0.073 13.2 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle DNA_pol_B PF00136.21 ETS84869.1 - 1.6e-101 340.3 0.0 2.3e-101 339.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 ETS84869.1 - 2.6e-23 82.7 0.1 1.2e-13 51.0 0.1 2.7 2 1 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 ETS84869.1 - 7.4e-17 61.6 5.3 7.4e-17 61.6 5.3 2.1 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta MMM1 PF10296.9 ETS84870.1 - 2.6e-06 26.8 0.6 8.4e-05 21.8 0.0 2.5 1 1 1 2 2 2 2 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 ETS84870.1 - 0.065 13.7 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain COX6A PF02046.15 ETS84871.1 - 3.4e-52 175.6 1.1 4.1e-52 175.4 1.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF2933 PF11666.8 ETS84871.1 - 0.16 12.0 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) Exo_endo_phos PF03372.23 ETS84872.1 - 5e-14 52.4 0.1 7.2e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 ETS84872.1 - 5.4e-05 23.2 0.9 0.00013 22.0 0.9 1.7 1 0 0 1 1 1 1 GRF zinc finger F-box-like PF12937.7 ETS84873.1 - 1.5e-05 24.8 0.4 6.2e-05 22.8 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ETS84873.1 - 0.00011 22.0 0.8 0.001 18.9 0.1 2.6 3 0 0 3 3 3 1 F-box domain TFIIF_alpha PF05793.12 ETS84874.1 - 0.012 14.2 7.1 0.024 13.3 7.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Myb_DNA-bind_4 PF13837.6 ETS84874.1 - 0.11 12.9 0.1 0.53 10.7 0.1 2.1 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain UPF0016 PF01169.19 ETS84875.1 - 1.3e-40 137.5 24.7 3.4e-20 72.1 9.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 G3P_acyltransf PF02660.15 ETS84875.1 - 1.1 9.3 13.3 6.4 6.8 0.2 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase DUF2070 PF09843.9 ETS84875.1 - 1.2 7.3 4.5 0.19 10.0 0.4 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) rhaM PF05336.13 ETS84876.1 - 9.3e-36 122.2 0.5 1.2e-35 121.8 0.5 1.1 1 0 0 1 1 1 1 L-rhamnose mutarotase Thioredoxin PF00085.20 ETS84877.1 - 2e-05 24.5 0.0 3.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ETS84877.1 - 0.22 12.0 0.0 1.3 9.5 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain MFS_1 PF07690.16 ETS84878.1 - 5.6e-40 137.3 25.4 2.3e-31 109.0 3.5 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS84878.1 - 5.1e-14 52.0 2.8 5.1e-14 52.0 2.8 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter VIT1 PF01988.19 ETS84878.1 - 0.011 15.6 2.1 18 5.1 0.2 3.4 3 0 0 3 3 3 0 VIT family ELP6 PF09807.9 ETS84879.1 - 2e-11 43.8 0.0 3e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Elongation complex protein 6 Ribosomal_L37e PF01907.19 ETS84880.1 - 4.1e-28 97.3 12.7 5.8e-28 96.8 12.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 ETS84880.1 - 0.0063 16.5 1.7 0.0094 16.0 1.7 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 ETS84880.1 - 0.15 12.1 1.0 0.2 11.7 1.0 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4_2 PF13923.6 ETS84880.1 - 0.19 11.6 2.9 0.34 10.8 2.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Autophagy_N PF03986.13 ETS84881.1 - 1.3e-46 157.9 0.1 1.3e-46 157.9 0.1 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 ETS84881.1 - 4.5e-16 58.0 0.6 9.8e-16 57.0 0.6 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 ETS84881.1 - 1.4e-15 57.6 0.0 2.7e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Xan_ur_permease PF00860.20 ETS84882.1 - 1.1e-24 86.9 31.4 2.1e-24 86.0 28.3 2.4 2 1 0 2 2 2 1 Permease family MFS_MOT1 PF16983.5 ETS84882.1 - 0.015 15.6 4.5 0.015 15.6 4.5 3.3 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily MFS_1 PF07690.16 ETS84883.1 - 7.3e-11 41.6 5.2 9.1e-11 41.3 5.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily FA_desaturase PF00487.24 ETS84883.1 - 0.017 15.0 0.8 0.022 14.6 0.8 1.3 1 0 0 1 1 1 0 Fatty acid desaturase DUF2427 PF10348.9 ETS84883.1 - 0.032 14.0 3.6 0.077 12.8 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) MFS_1 PF07690.16 ETS84884.1 - 6.4e-11 41.8 12.1 1.9e-10 40.2 12.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Metallophos PF00149.28 ETS84888.1 - 1.9e-13 51.4 0.9 2.9e-13 50.8 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ETS84888.1 - 1.5e-06 28.5 0.0 0.0043 17.3 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain DUF2052 PF09747.9 ETS84889.1 - 1.6e-27 96.9 15.8 3.4e-14 53.4 9.3 2.1 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) Mito_carr PF00153.27 ETS84891.1 - 2.1e-72 239.1 0.4 2e-23 82.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PX PF00787.24 ETS84892.1 - 1e-25 89.9 0.1 1.3e-25 89.6 0.1 1.1 1 0 0 1 1 1 1 PX domain ARPC4 PF05856.12 ETS84894.1 - 4e-60 202.2 10.3 1.8e-35 122.0 1.6 2.0 1 1 1 2 2 2 2 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.29 ETS84895.1 - 4.4e-49 167.3 0.0 6e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ETS84895.1 - 4e-13 49.7 6.5 5e-12 46.0 6.5 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 ETS84895.1 - 4.1e-11 42.5 0.0 7.6e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RRM_1 PF00076.22 ETS84896.1 - 1.7e-20 72.6 0.0 8.1e-09 35.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ETS84896.1 - 0.11 12.7 0.0 3.1 8.0 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif DUF1690 PF07956.11 ETS84897.1 - 3.6e-40 137.6 8.1 4.2e-40 137.4 8.1 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) DUF1993 PF09351.10 ETS84897.1 - 0.04 14.0 1.8 0.052 13.7 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Med9 PF07544.13 ETS84897.1 - 0.11 12.6 0.5 0.11 12.6 0.5 2.0 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Uso1_p115_C PF04871.13 ETS84897.1 - 8.1 6.8 14.2 53 4.2 14.2 2.1 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region CP12 PF02672.15 ETS84897.1 - 8.5 7.2 10.7 2.4 8.9 1.8 3.4 1 1 2 3 3 3 0 CP12 domain TYW3 PF02676.14 ETS84898.1 - 2.9e-75 252.3 0.0 3.5e-75 252.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 CBM-like PF14683.6 ETS84899.1 - 3.3e-38 131.2 0.0 6.6e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 ETS84899.1 - 2.6e-10 39.9 0.5 9.5e-10 38.1 0.3 2.2 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 ETS84899.1 - 5.5e-07 29.8 1.5 1.9e-06 28.0 0.6 2.3 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 ETS84899.1 - 0.014 15.4 0.0 0.9 9.6 0.0 2.7 2 1 0 2 2 2 0 CarboxypepD_reg-like domain DHHC PF01529.20 ETS84900.1 - 5.3e-36 123.7 4.1 5.3e-36 123.7 4.1 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase SpoVAC_SpoVAEB PF03862.13 ETS84900.1 - 0.0022 18.3 0.3 0.0045 17.2 0.3 1.4 1 0 0 1 1 1 1 SpoVAC/SpoVAEB sporulation membrane protein Yip1 PF04893.17 ETS84900.1 - 5.1 6.8 7.9 0.31 10.8 0.8 2.0 2 0 0 2 2 2 0 Yip1 domain CobD_Cbib PF03186.13 ETS84901.1 - 0.018 14.3 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 CobD/Cbib protein HAD PF12710.7 ETS84902.1 - 7.1e-21 75.5 0.1 1e-20 75.0 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETS84902.1 - 1.3e-17 64.8 1.4 1.9e-17 64.2 1.4 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ETS84902.1 - 2.6e-09 37.2 0.7 5.3e-08 32.9 0.1 2.7 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ETS84902.1 - 0.00019 21.6 0.1 0.0016 18.6 0.1 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.12 ETS84902.1 - 0.021 14.3 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) S6PP PF05116.13 ETS84902.1 - 0.08 12.5 0.5 0.53 9.8 0.0 2.4 2 1 1 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase Put_Phosphatase PF06888.12 ETS84902.1 - 0.093 12.1 0.0 10 5.4 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase PAPS_reduct PF01507.19 ETS84904.1 - 3.9e-41 141.0 0.0 5.7e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Fasciclin PF02469.22 ETS84905.1 - 8.2e-40 136.0 2.8 2.9e-19 69.6 0.1 2.1 2 0 0 2 2 2 2 Fasciclin domain HEAT PF02985.22 ETS84906.1 - 4.1e-16 57.7 11.6 0.0012 18.9 0.0 9.9 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.6 ETS84906.1 - 5.6e-13 49.1 7.4 1.5e-10 41.3 0.0 6.9 6 2 3 9 9 9 1 HEAT-like repeat HEAT_2 PF13646.6 ETS84906.1 - 7.8e-10 39.0 11.1 0.00046 20.5 0.0 6.9 2 2 5 7 7 7 5 HEAT repeats IBN_N PF03810.19 ETS84906.1 - 5.8e-08 32.5 3.4 3.9e-07 29.9 1.6 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.23 ETS84906.1 - 4.9e-05 23.2 3.6 2 8.6 0.1 6.1 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 ETS84906.1 - 0.00061 19.4 0.2 4.8 6.7 0.0 5.1 3 2 2 5 5 5 1 CLASP N terminal Cnd1 PF12717.7 ETS84906.1 - 0.0016 18.5 1.3 0.13 12.3 0.0 4.1 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DRIM PF07539.12 ETS84906.1 - 0.017 13.4 6.8 13 3.9 0.3 5.2 4 1 1 6 6 6 0 Down-regulated in metastasis HEAT_PBS PF03130.16 ETS84906.1 - 0.14 12.9 2.7 44 5.2 0.0 5.2 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat SAICAR_synt PF01259.18 ETS84907.1 - 3.4e-95 318.4 0.0 4e-95 318.2 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase HMGL-like PF00682.19 ETS84908.1 - 1.3e-78 264.2 0.0 1.9e-78 263.7 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 ETS84908.1 - 3.1e-23 82.1 0.0 6.3e-23 81.1 0.0 1.5 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain HNH_repeat PF18780.1 ETS84908.1 - 0.079 12.8 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Homing endonuclease repeat APH PF01636.23 ETS84910.1 - 3e-32 112.5 0.0 4.8e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 ETS84910.1 - 0.098 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase TMF_TATA_bd PF12325.8 ETS84911.1 - 0.00075 19.7 0.9 0.0016 18.6 0.9 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF4201 PF13870.6 ETS84911.1 - 0.0083 15.9 3.4 0.016 14.9 2.8 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) ATG16 PF08614.11 ETS84911.1 - 0.01 16.1 7.1 0.02 15.1 7.1 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 ETS84911.1 - 0.019 14.2 1.3 0.031 13.5 1.3 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF2353 PF09789.9 ETS84911.1 - 0.022 14.1 4.1 0.23 10.8 4.1 2.1 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Csm1_N PF18504.1 ETS84911.1 - 0.023 15.0 0.1 0.25 11.7 0.0 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain YabA PF06156.13 ETS84911.1 - 0.052 14.2 1.2 0.13 13.0 0.8 1.9 2 0 0 2 2 1 0 Initiation control protein YabA SPATA24 PF15175.6 ETS84911.1 - 0.058 13.3 0.4 0.11 12.4 0.4 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 CENP-F_leu_zip PF10473.9 ETS84911.1 - 0.061 13.3 1.2 0.12 12.4 1.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 ETS84911.1 - 0.066 13.4 0.3 0.12 12.5 0.3 1.4 1 0 0 1 1 1 0 Tropomyosin like MFMR_assoc PF16596.5 ETS84911.1 - 0.076 13.5 1.1 0.16 12.4 1.1 1.4 1 0 0 1 1 1 0 Disordered region downstream of MFMR HAUS-augmin3 PF14932.6 ETS84911.1 - 0.088 12.4 2.2 0.17 11.5 2.2 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 ETS84911.1 - 0.11 11.4 0.5 0.19 10.6 0.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 ETS84911.1 - 0.14 12.7 2.8 0.26 11.8 2.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 ETS84911.1 - 0.32 10.8 2.8 1.1 9.1 0.8 2.3 1 1 1 2 2 2 0 Septum formation initiator PAP1 PF08601.10 ETS84911.1 - 0.32 10.7 2.9 0.55 9.9 2.9 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 TPR_MLP1_2 PF07926.12 ETS84911.1 - 0.36 10.9 2.8 4.7 7.3 2.2 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 ETS84911.1 - 0.52 10.7 3.6 0.93 9.9 3.6 1.3 1 0 0 1 1 1 0 Fez1 Cep57_CLD_2 PF14197.6 ETS84911.1 - 1.7 8.8 6.1 4.7 7.4 6.1 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Atg14 PF10186.9 ETS84911.1 - 2.1 7.3 5.4 3.8 6.5 5.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NACHT PF05729.12 ETS84912.1 - 9.7e-14 51.6 0.1 3.6e-13 49.8 0.0 2.0 2 0 0 2 2 2 1 NACHT domain Ank_2 PF12796.7 ETS84912.1 - 4.3e-07 30.4 0.1 0.00016 22.2 0.1 3.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) PNP_UDP_1 PF01048.20 ETS84912.1 - 7.8e-07 28.6 0.1 1.8e-06 27.4 0.1 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.6 ETS84912.1 - 7.7e-06 26.4 0.1 3.4e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS84912.1 - 5.8e-05 23.4 0.0 0.00016 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Ank PF00023.30 ETS84912.1 - 0.00045 20.5 0.0 0.15 12.6 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat NB-ARC PF00931.22 ETS84912.1 - 0.001 18.3 0.0 0.0035 16.6 0.0 1.8 1 1 0 1 1 1 1 NB-ARC domain AAA PF00004.29 ETS84912.1 - 0.0013 19.1 0.1 0.0087 16.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ETS84912.1 - 0.0017 18.8 0.2 0.014 15.7 0.0 2.7 3 0 0 3 3 3 1 RNA helicase Torsin PF06309.11 ETS84912.1 - 0.003 17.6 0.0 0.011 15.9 0.0 2.0 2 0 0 2 2 1 1 Torsin AAA_14 PF13173.6 ETS84912.1 - 0.0039 17.2 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ETS84912.1 - 0.0062 16.5 0.0 0.017 15.0 0.0 1.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Ank_4 PF13637.6 ETS84912.1 - 0.0098 16.5 0.0 0.03 14.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Hydrolase_4 PF12146.8 ETS84913.1 - 0.00014 21.2 0.0 0.3 10.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS84913.1 - 0.00015 21.5 0.1 0.014 15.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS84913.1 - 0.00042 21.0 0.1 0.00048 20.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 ETS84913.1 - 0.025 14.2 0.3 0.04 13.5 0.2 1.3 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DAO PF01266.24 ETS84914.1 - 6.7e-33 114.7 0.3 7.6e-33 114.5 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 ETS84914.1 - 0.012 16.0 0.0 0.021 15.2 0.0 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 ETS84914.1 - 0.016 14.4 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS84914.1 - 0.019 14.1 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 ETS84914.1 - 0.035 14.7 0.0 0.07 13.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS84914.1 - 0.037 13.3 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS84914.1 - 0.045 14.0 1.5 0.066 13.5 0.4 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ETS84914.1 - 0.056 12.7 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 ETS84914.1 - 0.13 11.9 0.1 0.29 10.8 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ferric_reduct PF01794.19 ETS84915.1 - 2.6e-22 79.3 6.5 2.6e-22 79.3 6.5 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ETS84915.1 - 1e-17 64.7 0.0 8.7e-16 58.4 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ETS84915.1 - 3.1e-11 43.3 0.0 2.7e-06 27.4 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain ANTH PF07651.16 ETS84916.1 - 1.8e-82 276.4 0.0 1.8e-82 276.4 0.0 3.3 3 1 0 4 4 4 1 ANTH domain I_LWEQ PF01608.17 ETS84916.1 - 4.1e-54 183.0 10.6 4.1e-54 183.0 10.6 5.9 4 3 3 7 7 7 1 I/LWEQ domain CIA30 PF08547.12 ETS84917.1 - 4.3e-46 156.9 0.0 5.3e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) ANAPC5 PF12862.7 ETS84918.1 - 1.3e-33 114.9 12.0 2.1e-33 114.3 5.5 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_7 PF13176.6 ETS84918.1 - 0.00046 20.0 0.2 21 5.4 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 ETS84918.1 - 0.0017 18.1 2.3 2.8 7.9 0.1 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS84918.1 - 0.0089 16.5 11.0 16 6.1 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 ETS84918.1 - 0.01 15.6 0.3 21 5.1 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 ETS84918.1 - 0.027 14.7 0.6 43 4.7 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 ETS84918.1 - 0.039 14.2 13.3 0.89 9.9 0.0 6.2 6 1 2 8 8 8 0 Tetratricopeptide repeat MAT1-1-2 PF17043.5 ETS84919.1 - 1.9e-06 27.8 0.0 3.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Mating type protein 1-1-2 of unknown function HMG_box PF00505.19 ETS84921.1 - 2.9e-13 50.0 3.7 2.9e-13 50.0 3.7 2.4 1 1 1 2 2 2 1 HMG (high mobility group) box Rrn6 PF10214.9 ETS84921.1 - 0.023 13.2 6.5 0.037 12.5 6.5 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TAF4 PF05236.14 ETS84921.1 - 0.062 13.0 6.8 0.088 12.5 6.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family CAS_C PF12026.8 ETS84921.1 - 0.079 13.0 2.9 0.17 11.9 2.9 1.6 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain CPSF100_C PF13299.6 ETS84921.1 - 1.1 9.4 5.9 3 8.0 5.9 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 ETS84921.1 - 2 8.2 12.8 3.6 7.3 12.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 ETS84921.1 - 5.7 5.6 10.6 10 4.8 10.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Glutenin_hmw PF03157.13 ETS84922.1 - 0.0012 17.4 22.6 0.0019 16.7 22.6 1.2 1 0 0 1 1 1 1 High molecular weight glutenin subunit zf-C6H2 PF15801.5 ETS84923.1 - 0.0033 17.7 4.2 0.0033 17.7 4.2 3.0 3 0 0 3 3 3 2 zf-MYND-like zinc finger, mRNA-binding PLATZ PF04640.14 ETS84923.1 - 0.03 14.9 8.4 1 10.0 1.0 3.3 2 1 0 2 2 2 0 PLATZ transcription factor zf-MYND PF01753.18 ETS84923.1 - 9.1 6.5 21.1 0.25 11.4 3.9 3.5 3 1 0 3 3 3 0 MYND finger MAGE PF01454.19 ETS84924.1 - 7.7e-64 215.3 0.0 1e-63 214.9 0.0 1.2 1 0 0 1 1 1 1 MAGE family GEMIN8 PF15348.6 ETS84924.1 - 0.22 11.8 2.7 0.57 10.4 2.7 1.6 1 1 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 SLS PF14611.6 ETS84925.1 - 1.1e-32 113.7 1.8 1.1e-32 113.7 1.8 1.9 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator RmlD_sub_bind PF04321.17 ETS84925.1 - 0.078 12.1 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain GTP_EFTU PF00009.27 ETS84926.1 - 8.2e-56 188.6 0.1 1.1e-55 188.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ETS84926.1 - 6e-42 142.5 0.0 1.3e-41 141.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ETS84926.1 - 1.7e-14 53.9 1.5 2.6e-14 53.3 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ETS84926.1 - 7e-05 22.9 0.3 0.0019 18.3 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 ETS84926.1 - 0.064 13.2 1.1 0.12 12.3 0.2 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.23 ETS84926.1 - 0.067 13.2 0.1 17 5.4 0.1 2.5 2 0 0 2 2 2 0 Dynamin family FeoB_N PF02421.18 ETS84926.1 - 0.15 11.6 0.2 2 7.9 0.0 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B Fungal_trans PF04082.18 ETS84928.1 - 5.3e-16 58.4 0.4 8.8e-16 57.7 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS84928.1 - 0.0017 18.5 7.0 0.0029 17.7 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 ETS84929.1 - 1.5e-57 195.4 0.0 1.8e-57 195.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sec2p PF06428.11 ETS84930.1 - 4.2e-28 97.1 22.6 4.9e-28 96.9 16.5 2.4 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF3584 PF12128.8 ETS84930.1 - 1.2 6.6 24.2 1.9 5.9 24.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF5401 PF17380.2 ETS84930.1 - 2.7 5.9 22.8 4.1 5.4 22.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Peptidase_S46 PF10459.9 ETS84930.1 - 3.9 6.0 13.2 5.8 5.4 13.2 1.1 1 0 0 1 1 1 0 Peptidase S46 Helo_like_N PF17111.5 ETS84932.1 - 0.17 11.2 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Pro-kuma_activ PF09286.11 ETS84933.1 - 1.6e-41 141.9 0.0 4.3e-41 140.5 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain DUF3433 PF11915.8 ETS84934.1 - 2e-28 98.7 19.9 2.4e-27 95.2 3.9 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Transgly_assoc PF04226.13 ETS84934.1 - 1.1 9.5 4.1 16 5.8 0.4 2.7 2 0 0 2 2 2 0 Transglycosylase associated protein Borrelia_P83 PF05262.11 ETS84936.1 - 1.2 7.5 8.1 8.7 4.7 0.1 2.1 2 0 0 2 2 2 0 Borrelia P83/100 protein SCO1-SenC PF02630.14 ETS84937.1 - 1e-48 164.7 0.0 1.5e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 ETS84937.1 - 5.5e-05 23.1 0.0 0.00012 22.0 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ETS84937.1 - 0.041 13.6 0.0 1.1 8.9 0.0 2.2 1 1 0 1 1 1 0 Redoxin Ank_4 PF13637.6 ETS84940.1 - 1.2e-07 32.1 0.1 0.052 14.1 0.0 4.7 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS84940.1 - 1.4e-06 28.8 0.0 2.3 8.9 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS84940.1 - 1e-05 25.5 0.1 1.2 9.9 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 ETS84940.1 - 0.00073 19.9 3.6 0.49 10.9 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 ETS84940.1 - 0.055 13.8 0.5 4.3 7.8 0.0 3.6 3 1 0 3 3 3 0 Ankyrin repeats (many copies) RicinB_lectin_2 PF14200.6 ETS84941.1 - 1.7e-23 83.1 8.2 1.7e-15 57.5 0.9 2.3 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 ETS84941.1 - 9.2e-08 32.4 1.1 8.9e-07 29.2 1.0 2.3 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain 4HBT_3 PF13622.6 ETS84942.1 - 9.6e-40 137.4 0.5 1.2e-39 137.1 0.5 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 ETS84942.1 - 0.00056 20.2 0.1 1.1 9.7 0.1 2.4 2 0 0 2 2 2 2 Thioesterase superfamily Acyl_CoA_thio PF02551.15 ETS84942.1 - 0.0066 16.3 0.7 6.8 6.5 0.1 2.8 2 1 1 3 3 3 2 Acyl-CoA thioesterase ADH_zinc_N PF00107.26 ETS84943.1 - 2.2e-20 72.9 0.0 3.5e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ETS84943.1 - 3.3e-19 68.8 0.0 6e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ETS84943.1 - 1e-07 33.1 0.0 1.8e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PSDC PF12588.8 ETS84944.1 - 3.5e-32 111.3 0.4 5.7e-32 110.6 0.4 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 ETS84944.1 - 5.2e-26 91.4 0.0 7.8e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase F-box PF00646.33 ETS84945.1 - 2.8 7.9 5.3 1.1 9.2 2.0 2.0 2 0 0 2 2 2 0 F-box domain HET PF06985.11 ETS84947.1 - 4.1e-14 53.2 4.8 4.3e-11 43.4 0.5 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) DUF1523 PF07509.11 ETS84947.1 - 0.067 12.6 0.4 18 4.7 0.0 3.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1523) Lipase_C PF18067.1 ETS84947.1 - 0.092 13.3 0.0 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 Lipase C-terminal domain VCBS PF13517.6 ETS84947.1 - 0.18 12.4 5.0 0.5 11.0 0.2 3.6 3 1 1 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipocalin_4 PF13648.6 ETS84947.1 - 0.81 10.7 9.0 1 10.4 3.5 3.1 2 1 1 3 3 3 0 Lipocalin-like domain DTHCT PF08070.11 ETS84948.1 - 0.066 14.0 7.5 0.098 13.4 7.5 1.3 1 0 0 1 1 1 0 DTHCT (NUC029) region Glyco_hydro_43 PF04616.14 ETS84949.1 - 7e-41 140.4 8.1 9.4e-41 140.0 8.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 VCBS PF13517.6 ETS84950.1 - 0.36 11.5 5.7 5 7.8 0.1 3.7 4 1 0 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF346 PF03984.13 ETS84950.1 - 0.55 10.0 6.4 0.67 9.8 0.1 3.9 4 0 0 4 4 4 0 Repeat of unknown function (DUF346) p450 PF00067.22 ETS84951.1 - 1.5e-38 132.8 0.0 1.7e-38 132.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 ETS84953.1 - 0.1 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF1082 PF06449.11 ETS84954.1 - 0.083 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1082) EcKinase PF02958.20 ETS84955.1 - 3.9e-16 59.2 0.0 1.6e-13 50.7 0.0 2.2 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 ETS84955.1 - 1.2e-08 34.3 0.1 2.1e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 ETS84955.1 - 4.5e-08 33.3 0.3 6.9e-08 32.7 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family TRI5 PF06330.11 ETS84956.1 - 2.5e-14 52.9 0.0 3.2e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) fn3_3 PF14686.6 ETS84957.1 - 9.9e-15 54.1 3.5 1.6e-14 53.4 3.5 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 ETS84957.1 - 7.9e-06 25.8 0.1 1.6e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III RhgB_N PF09284.10 ETS84957.1 - 0.00024 20.7 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CarboxypepD_reg PF13620.6 ETS84957.1 - 0.0021 18.3 1.6 0.0039 17.4 1.6 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Acylphosphatase PF00708.18 ETS84957.1 - 0.017 15.5 0.0 0.04 14.3 0.0 1.6 1 0 0 1 1 1 0 Acylphosphatase CBM-like PF14683.6 ETS84958.1 - 5.3e-27 94.7 0.1 9.8e-27 93.8 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 ETS84958.1 - 6.5e-22 77.1 0.0 2e-21 75.5 0.0 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II Glyco_hydro_79C PF16862.5 ETS84959.1 - 7.6e-15 55.7 0.1 1.6e-14 54.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_28 PF00295.17 ETS84960.1 - 1.4e-18 67.0 0.1 9.1e-18 64.4 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_2_N PF02837.18 ETS84961.1 - 7.4e-11 42.2 0.5 1.4e-10 41.3 0.3 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4982 PF16355.5 ETS84962.1 - 1.7e-11 43.9 0.0 4.7e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Glyco_hydro2_C5 PF18565.1 ETS84962.1 - 6.9e-09 35.5 0.1 3.8e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 Glycoside hydrolase family 2 C-terminal domain 5 F5_F8_type_C PF00754.25 ETS84962.1 - 0.00039 20.5 4.9 0.00045 20.3 3.2 2.0 2 0 0 2 2 2 1 F5/8 type C domain MAM PF00629.23 ETS84962.1 - 0.37 10.7 2.4 0.44 10.5 0.2 2.1 2 0 0 2 2 2 0 MAM domain, meprin/A5/mu Glyco_hydro_10 PF00331.20 ETS84963.1 - 5.1e-88 295.3 0.7 1.2e-83 280.9 0.9 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 10 Lipase_GDSL_2 PF13472.6 ETS84964.1 - 9.7e-14 52.1 0.7 1.2e-13 51.8 0.7 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS84964.1 - 6.9e-08 32.7 0.1 9.5e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SASA PF03629.18 ETS84964.1 - 0.057 13.0 0.1 0.1 12.2 0.1 1.5 1 1 0 1 1 1 0 Carbohydrate esterase, sialic acid-specific acetylesterase RNase_PH PF01138.21 ETS84965.1 - 2.8e-17 63.5 0.0 6.7e-17 62.2 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ETS84965.1 - 0.046 13.8 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Ferric_reduct PF01794.19 ETS84966.1 - 2.5e-18 66.4 4.8 2.5e-18 66.4 4.8 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ETS84966.1 - 1.3e-13 51.4 0.0 8.2e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ETS84966.1 - 1.2e-12 47.9 0.1 3.9e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 ETS84966.1 - 0.0022 18.6 0.0 0.47 11.1 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 ETS84966.1 - 0.54 10.8 5.0 0.11 13.0 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) HET PF06985.11 ETS84967.1 - 1.2e-09 38.6 12.1 1.1e-07 32.3 2.7 2.6 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Hydrolase_6 PF13344.6 ETS84968.1 - 1.7e-25 89.0 0.0 4.9e-25 87.6 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ETS84968.1 - 2.9e-19 68.9 0.0 7e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ETS84968.1 - 1.8e-06 28.4 0.2 0.022 15.1 0.1 3.5 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ETS84968.1 - 0.0011 19.1 0.3 0.34 11.0 0.1 2.9 3 2 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ETS84968.1 - 0.083 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Choline_kinase PF01633.20 ETS84969.1 - 1.3e-56 191.6 0.0 5.8e-56 189.4 0.0 2.2 1 1 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 ETS84969.1 - 3.2e-21 74.7 0.0 7.7e-21 73.5 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus PHD PF00628.29 ETS84970.1 - 2.9e-11 43.1 7.2 2.9e-11 43.1 7.2 2.3 2 0 0 2 2 2 1 PHD-finger zf-C2H2 PF00096.26 ETS84972.1 - 1.7e-08 34.5 13.1 0.00046 20.5 2.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ETS84972.1 - 1.4e-05 25.3 10.5 4.3e-05 23.7 2.3 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ETS84972.1 - 0.00018 22.0 12.1 0.11 13.4 1.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ETS84972.1 - 0.01 15.8 0.9 0.01 15.8 0.9 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 ETS84972.1 - 0.027 14.9 3.7 0.071 13.5 1.6 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ETS84972.1 - 0.076 13.3 0.4 0.076 13.3 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 ETS84972.1 - 0.25 11.5 2.0 2.1 8.5 0.8 2.3 1 1 1 2 2 2 0 Zinc ribbon domain PI3Ka PF00613.20 ETS84973.1 - 1e-57 194.5 2.7 2e-57 193.6 2.7 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 ETS84973.1 - 2.4e-46 158.6 0.0 4.1e-31 108.7 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 ETS84973.1 - 5.9e-31 107.3 0.0 1.3e-30 106.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.10 ETS84974.1 - 6.3e-30 103.3 0.0 1.7e-29 101.9 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 ETS84974.1 - 5.5e-13 48.8 1.8 9.6e-13 48.0 0.0 2.3 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE APG6_N PF17675.1 ETS84975.1 - 0.00063 20.3 18.6 0.00063 20.3 18.6 11.5 4 2 6 10 10 10 4 Apg6 coiled-coil region DUF4336 PF14234.6 ETS84976.1 - 1.2e-15 57.5 0.1 6.6e-11 42.0 0.0 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) AA_permease_2 PF13520.6 ETS84977.1 - 9.7e-67 225.6 13.5 1.3e-66 225.3 13.5 1.1 1 0 0 1 1 1 1 Amino acid permease ALO PF04030.14 ETS84978.1 - 4.7e-91 305.2 0.7 7.3e-91 304.6 0.7 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 ETS84978.1 - 3e-28 98.3 0.0 4.2e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GyrI-like PF06445.15 ETS84978.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 GyrI-like small molecule binding domain CNH PF00780.22 ETS84980.1 - 1.2e-79 267.8 0.0 4.7e-79 265.9 0.0 1.8 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 ETS84980.1 - 2.7e-40 137.6 0.1 5.6e-40 136.6 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 ETS84980.1 - 2e-34 119.4 0.6 4.3e-34 118.3 0.1 1.8 2 0 0 2 2 2 1 RhoGEF domain DEP PF00610.21 ETS84980.1 - 7.8e-16 57.9 0.0 1.6e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP-synt_C PF00137.21 ETS84981.1 - 3.1e-28 97.9 34.7 7.7e-17 61.4 11.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ELP6 PF09807.9 ETS84981.1 - 0.18 11.2 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Elongation complex protein 6 FPN1 PF06963.12 ETS84981.1 - 3 6.3 7.9 6.8 5.1 0.0 2.8 2 1 0 2 2 2 0 Ferroportin1 (FPN1) FAM176 PF14851.6 ETS84983.1 - 0.033 13.9 2.8 0.046 13.4 2.8 1.3 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 ETS84983.1 - 2.3 6.4 9.2 2.6 6.2 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Rad21_Rec8_N PF04825.13 ETS84984.1 - 9.4e-31 106.2 0.1 1.5e-30 105.5 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 ETS84984.1 - 8.2e-08 31.4 0.0 1.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein AT_hook PF02178.19 ETS84984.1 - 0.66 10.0 5.4 1.7 8.8 5.4 1.7 1 0 0 1 1 1 0 AT hook motif GDI PF00996.18 ETS84985.1 - 6.9e-21 74.3 0.0 2.2e-14 52.8 0.0 3.0 2 2 0 2 2 2 2 GDP dissociation inhibitor DUF202 PF02656.15 ETS84988.1 - 1.2e-17 64.1 0.2 9.9e-17 61.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Tma16 PF11176.8 ETS84988.1 - 0.016 15.1 0.0 0.018 14.9 0.0 1.1 1 0 0 1 1 1 0 Translation machinery-associated protein 16 AAA_13 PF13166.6 ETS84989.1 - 0.0018 17.0 0.9 0.0021 16.8 0.9 1.1 1 0 0 1 1 1 1 AAA domain DUF327 PF03885.13 ETS84989.1 - 0.0038 17.2 1.9 0.27 11.2 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF327) Pox_A_type_inc PF04508.12 ETS84989.1 - 0.0065 16.3 0.6 0.0065 16.3 0.6 2.1 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat Not3 PF04065.15 ETS84989.1 - 0.016 14.6 1.2 0.016 14.6 1.2 1.9 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component UreE_C PF05194.12 ETS84989.1 - 0.035 14.6 9.3 0.079 13.5 9.3 1.6 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain DASH_Dad2 PF08654.10 ETS84989.1 - 0.038 14.4 1.0 1.3 9.5 0.6 2.3 1 1 1 2 2 2 0 DASH complex subunit Dad2 DUF5595 PF18077.1 ETS84989.1 - 0.055 13.6 1.0 0.39 10.8 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) BBP1_C PF15272.6 ETS84989.1 - 0.061 13.1 6.6 0.13 12.1 6.5 1.6 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF1664 PF07889.12 ETS84989.1 - 0.11 12.6 2.4 0.42 10.7 2.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Rad50_zn_hook PF04423.14 ETS84989.1 - 0.46 10.4 1.8 28 4.7 0.1 2.7 2 1 0 2 2 2 0 Rad50 zinc hook motif Fib_alpha PF08702.10 ETS84989.1 - 0.62 10.2 4.3 1 9.5 4.3 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2203 PF09969.9 ETS84989.1 - 1.4 9.6 5.0 8.9 7.1 0.4 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Edc3_linker PF16598.5 ETS84989.1 - 4.3 8.1 14.6 16 6.3 0.1 2.7 3 0 0 3 3 3 0 Linker region of enhancer of mRNA-decapping protein 3 ADH_zinc_N PF00107.26 ETS84991.1 - 4.8e-14 52.5 0.0 7.6e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UQ_con PF00179.26 ETS84992.1 - 2.4e-46 156.9 0.0 2.7e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ETS84992.1 - 0.00025 20.7 0.0 0.00033 20.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 ETS84992.1 - 0.062 13.2 0.1 0.12 12.2 0.1 1.5 1 1 0 1 1 1 0 UEV domain WD40 PF00400.32 ETS84993.1 - 7.3e-09 36.1 20.2 0.00061 20.5 0.2 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 ETS84993.1 - 1.5e-07 30.9 11.2 3e-07 29.9 11.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 ETS84993.1 - 0.11 12.8 5.4 0.24 11.7 5.4 1.5 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 ETS84993.1 - 0.59 10.5 7.9 1.8 8.9 7.9 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain Ank_2 PF12796.7 ETS84994.1 - 6.5e-79 260.6 1.3 6.2e-17 62.0 0.0 5.9 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS84994.1 - 2.1e-51 171.6 0.9 2.7e-11 43.8 0.0 7.5 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 ETS84994.1 - 2.7e-51 169.9 0.4 4e-06 27.0 0.0 9.8 9 0 0 9 9 9 9 Ankyrin repeat Ank_5 PF13857.6 ETS84994.1 - 1.3e-48 162.4 3.3 1.6e-10 41.0 0.1 6.5 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS84994.1 - 3.2e-38 125.4 0.1 0.0023 18.3 0.0 10.1 10 0 0 10 10 10 6 Ankyrin repeat AAA_33 PF13671.6 ETS84994.1 - 2.2e-07 31.1 0.0 5.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS84994.1 - 2.4e-06 28.0 0.0 7.7e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS84994.1 - 1.2e-05 25.6 0.0 2.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ETS84994.1 - 9.8e-05 22.4 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 ETS84994.1 - 0.00013 22.5 0.0 0.00033 21.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 ETS84994.1 - 0.0036 16.5 0.0 0.0053 16.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 ETS84994.1 - 0.084 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 ETS84994.1 - 0.095 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TPR_12 PF13424.6 ETS84994.1 - 0.12 12.7 0.1 0.94 9.8 0.1 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat KTI12 PF08433.10 ETS84994.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PNP_UDP_1 PF01048.20 ETS84995.1 - 0.0031 16.8 0.0 0.023 14.0 0.0 2.1 2 0 0 2 2 2 1 Phosphorylase superfamily F-box PF00646.33 ETS84996.1 - 0.0052 16.6 0.4 0.0052 16.6 0.4 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ETS84996.1 - 0.0056 16.6 1.4 0.011 15.6 0.4 2.1 1 1 0 1 1 1 1 F-box-like p450 PF00067.22 ETS84997.1 - 7.5e-65 219.5 0.0 9e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 ETS84998.1 - 2e-16 60.0 0.0 2.8e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS84998.1 - 6e-10 39.1 0.0 8.1e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS84998.1 - 0.00015 21.7 0.1 0.00048 20.1 0.1 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS84998.1 - 0.058 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4888 PF16229.5 ETS84998.1 - 0.12 12.4 0.8 4.6 7.2 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4888) NAD_binding_10 PF13460.6 ETS84998.1 - 0.18 11.7 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Pal1 PF08316.11 ETS84999.1 - 9.1e-48 162.5 0.3 9.1e-48 162.5 0.3 2.0 2 0 0 2 2 2 1 Pal1 cell morphology protein Fasciclin PF02469.22 ETS85001.1 - 2.6e-45 153.7 0.0 2.7e-23 82.6 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Glyco_hydro_88 PF07470.13 ETS85002.1 - 7.1e-40 137.1 1.1 1.3e-38 133.0 0.8 2.4 1 1 1 2 2 2 1 Glycosyl Hydrolase Family 88 F-box-like PF12937.7 ETS85003.1 - 0.00018 21.4 1.2 0.00047 20.0 0.1 2.2 2 0 0 2 2 2 1 F-box-like Rrp40_N PF18311.1 ETS85004.1 - 1.2e-18 66.8 1.5 1.2e-18 66.8 1.5 2.1 3 0 0 3 3 3 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 ETS85004.1 - 4.9e-16 58.8 0.0 1.9e-15 56.9 0.0 2.1 2 0 0 2 2 2 1 KH domain HSP70 PF00012.20 ETS85005.1 - 6e-75 252.6 1.7 6e-75 252.6 1.7 1.9 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 ETS85005.1 - 3.9e-07 29.2 0.4 6e-07 28.6 0.4 1.3 1 0 0 1 1 1 1 MreB/Mbl protein DUF3221 PF11518.8 ETS85005.1 - 0.0095 16.3 1.4 0.033 14.6 1.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3221) Pap_E4 PF02711.14 ETS85005.1 - 0.029 15.3 0.6 0.095 13.7 0.6 1.8 1 0 0 1 1 1 0 E4 protein Peripla_BP_6 PF13458.6 ETS85005.1 - 0.042 13.5 1.3 0.082 12.5 1.1 1.5 1 1 0 1 1 1 0 Periplasmic binding protein FAM176 PF14851.6 ETS85005.1 - 0.083 12.5 1.9 0.17 11.6 1.9 1.5 1 0 0 1 1 1 0 FAM176 family PI3K_1B_p101 PF10486.9 ETS85005.1 - 0.21 9.3 0.3 0.35 8.6 0.1 1.4 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_pol_phi PF04931.13 ETS85005.1 - 0.6 8.1 5.0 0.89 7.6 5.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 ETS85005.1 - 1.2 8.4 6.6 1.8 7.8 6.6 1.2 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 ETS85005.1 - 1.5 8.6 7.2 0.4 10.5 3.5 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Vfa1 PF08432.10 ETS85005.1 - 3.3 8.0 5.9 2.6 8.3 1.7 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 YbaB_DNA_bd PF02575.16 ETS85005.1 - 6.1 7.1 6.5 2.7 8.3 0.9 3.0 3 1 0 3 3 3 0 YbaB/EbfC DNA-binding family NT-C2 PF10358.9 ETS85006.1 - 6.9e-25 87.5 0.0 2e-20 73.0 0.0 2.4 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins POP1 PF06978.11 ETS85007.1 - 7.3e-68 228.6 16.2 7.3e-68 228.6 16.2 1.7 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 ETS85007.1 - 1.5e-28 98.9 0.1 1.5e-28 98.9 0.1 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain FAD_binding_4 PF01565.23 ETS85008.1 - 3.6e-17 62.4 1.5 5.2e-17 61.9 1.5 1.2 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 ETS85008.1 - 2.7e-08 33.9 0.6 0.00018 21.5 0.1 2.3 3 0 0 3 3 3 2 D-arabinono-1,4-lactone oxidase SH3_9 PF14604.6 ETS85008.1 - 0.09 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Variant SH3 domain 2OG-FeII_Oxy_2 PF13532.6 ETS85009.1 - 7.3e-20 72.0 1.4 2.6e-19 70.2 0.0 2.4 3 1 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily Acyl-CoA_dh_1 PF00441.24 ETS85012.1 - 3.9e-33 114.8 0.9 5.4e-33 114.3 0.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ETS85012.1 - 1.9e-21 76.1 0.2 3.1e-21 75.4 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ETS85012.1 - 6.7e-17 62.2 0.0 2.5e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ETS85012.1 - 5.9e-06 26.6 0.4 9.3e-06 26.0 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RRM_1 PF00076.22 ETS85013.1 - 7.6e-18 64.1 0.0 5.9e-13 48.4 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ETS85013.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Ras PF00071.22 ETS85014.1 - 5.3e-48 162.7 0.0 6.2e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS85014.1 - 3.7e-15 56.2 0.0 5.7e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS85014.1 - 1.7e-05 24.4 0.0 2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ETS85014.1 - 0.00091 18.8 0.0 0.0021 17.6 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ETS85014.1 - 0.024 14.6 0.0 0.42 10.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DUF5305 PF17231.2 ETS85016.1 - 0.075 12.4 0.1 0.5 9.7 0.0 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5305) EGF_2 PF07974.13 ETS85016.1 - 8 6.9 12.2 14 6.2 12.2 1.3 1 0 0 1 1 1 0 EGF-like domain BNR PF02012.20 ETS85018.1 - 0.068 13.2 0.4 0.22 11.6 0.4 2.0 1 0 0 1 1 1 0 BNR/Asp-box repeat Amidohydro_3 PF07969.11 ETS85019.1 - 2.2e-13 50.5 0.9 2.1e-09 37.4 0.3 3.1 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 ETS85019.1 - 3.2e-10 39.8 0.8 1.3e-08 34.6 0.0 3.0 3 1 0 4 4 4 1 Amidohydrolase family NmrA PF05368.13 ETS85020.1 - 1.7e-55 188.1 0.1 2.2e-55 187.8 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS85020.1 - 1.2e-17 64.4 0.0 1.8e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ETS85020.1 - 0.00052 19.1 0.1 0.00072 18.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 ETS85020.1 - 0.0045 17.3 0.1 0.18 12.1 0.1 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 ETS85021.1 - 5.1e-26 91.3 0.0 7.4e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS85021.1 - 9.5e-24 84.2 0.0 1.2e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS85021.1 - 3e-05 24.0 0.1 4.7e-05 23.4 0.1 1.5 1 1 0 1 1 1 1 KR domain MlaE PF02405.16 ETS85021.1 - 0.051 13.2 0.1 0.085 12.5 0.1 1.3 1 0 0 1 1 1 0 Permease MlaE Abhydrolase_1 PF00561.20 ETS85023.1 - 1.7e-12 47.5 0.0 2.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS85023.1 - 7.4e-10 39.8 0.0 1.3e-09 39.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS85023.1 - 1.6e-05 24.3 0.0 3.7e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 ETS85023.1 - 4.2e-05 22.4 0.0 6.6e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Ndr family EthD PF07110.11 ETS85023.1 - 0.0011 20.1 0.3 1.3 10.2 0.0 2.8 3 0 0 3 3 3 2 EthD domain DUF4286 PF14114.6 ETS85023.1 - 0.0017 18.8 0.3 0.4 11.2 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4286) Esterase PF00756.20 ETS85023.1 - 0.043 13.5 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Slx4 PF09494.10 ETS85024.1 - 0.14 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Slx4 endonuclease RdRP PF05183.12 ETS85026.1 - 3.2e-177 590.7 0.0 4e-177 590.4 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Amino_oxidase PF01593.24 ETS85027.1 - 3.6e-05 23.2 0.0 4.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 ETS85027.1 - 0.002 17.5 0.0 0.0067 15.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS85027.1 - 0.006 15.9 0.1 0.0084 15.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ETS85027.1 - 0.05 12.6 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 ETS85027.1 - 0.092 13.3 0.0 0.69 10.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS85027.1 - 0.11 12.7 0.3 0.53 10.6 0.3 2.2 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ETS85027.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 ETS85027.1 - 0.16 12.0 0.0 0.45 10.5 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 ETS85027.1 - 0.18 10.5 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein zf-UBR PF02207.20 ETS85028.1 - 5.9e-14 52.0 9.6 8.9e-14 51.4 9.6 1.3 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Helo_like_N PF17111.5 ETS85028.1 - 0.95 8.8 4.6 0.25 10.7 0.1 2.2 2 1 1 3 3 3 0 Fungal N-terminal domain of STAND proteins Lactamase_B PF00753.27 ETS85029.1 - 5.9e-05 23.2 0.7 0.00017 21.7 0.5 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS85029.1 - 0.0042 16.6 0.0 0.0096 15.5 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain GDP_Man_Dehyd PF16363.5 ETS85030.1 - 5.2e-70 236.5 0.0 6.1e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ETS85030.1 - 1.1e-59 201.8 0.0 1.5e-59 201.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS85030.1 - 7.2e-23 81.0 0.0 9.9e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ETS85030.1 - 3.6e-21 75.6 0.0 4.1e-20 72.1 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ETS85030.1 - 3.9e-15 55.7 0.0 5e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ETS85030.1 - 4.2e-15 55.6 0.1 9.6e-14 51.2 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 ETS85030.1 - 2.4e-06 27.6 0.0 6.2e-06 26.2 0.0 1.7 2 1 0 2 2 2 1 NAD(P)H-binding Pkinase PF00069.25 ETS85031.1 - 3.8e-55 187.1 0.3 7.8e-36 123.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS85031.1 - 1.5e-36 126.1 0.1 9.1e-36 123.5 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS85031.1 - 0.00013 21.4 0.0 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ETS85031.1 - 0.0052 16.7 1.1 0.054 13.4 0.0 2.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ETS85031.1 - 0.082 11.7 0.6 0.31 9.8 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase DUF3896 PF13035.6 ETS85031.1 - 0.084 13.0 1.5 0.4 10.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) TMF_DNA_bd PF12329.8 ETS85031.1 - 0.64 10.1 9.0 0.53 10.3 4.7 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding BTB PF00651.31 ETS85032.1 - 1.9e-25 89.2 0.0 2e-12 47.3 0.1 3.2 3 0 0 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 ETS85032.1 - 9.5e-08 32.4 0.0 2.2e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS85032.1 - 1.1e-06 29.1 0.0 2.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS85032.1 - 2.8e-05 24.3 0.0 7.6e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 ETS85032.1 - 0.00018 21.8 0.2 0.03 14.8 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 ETS85032.1 - 0.00019 21.6 0.1 0.19 12.4 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Metallophos PF00149.28 ETS85034.1 - 3.4e-10 40.8 2.6 7.8e-10 39.6 2.6 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 ETS85034.1 - 0.038 14.2 0.1 8.7 6.5 0.0 2.9 1 1 1 2 2 2 0 5'-nucleotidase, C-terminal domain Amidase PF01425.21 ETS85035.1 - 2.8e-102 343.0 0.0 4.6e-102 342.3 0.0 1.3 1 0 0 1 1 1 1 Amidase PRP38 PF03371.15 ETS85036.1 - 1e-53 181.7 0.0 1.4e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 ETS85036.1 - 0.00065 20.3 36.6 0.0012 19.5 36.6 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Isy1 PF06246.12 ETS85037.1 - 9e-83 277.7 0.8 1e-82 277.5 0.8 1.0 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.10 ETS85037.1 - 0.0072 16.4 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 YolD-like protein Thrombin_light PF09396.10 ETS85037.1 - 0.1 12.4 1.0 0.43 10.4 0.1 2.2 2 0 0 2 2 2 0 Thrombin light chain DUF5103 PF17116.5 ETS85037.1 - 0.16 11.2 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5103) Acetyltransf_3 PF13302.7 ETS85038.1 - 1.2e-19 71.3 0.0 1.5e-19 71.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS85038.1 - 0.00063 20.0 0.1 0.0059 16.8 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ETS85038.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Hepsin-SRCR PF09272.10 ETS85039.1 - 0.087 13.4 0.1 0.13 12.7 0.1 1.4 1 0 0 1 1 1 0 Hepsin, SRCR domain NACHT PF05729.12 ETS85040.1 - 7.6e-11 42.2 0.0 2.1e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ETS85040.1 - 0.00071 19.9 0.1 0.0053 17.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ETS85040.1 - 0.0017 18.9 0.0 0.0088 16.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain SesA PF17107.5 ETS85040.1 - 0.0043 17.2 0.9 0.013 15.7 0.9 1.8 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases RNA_helicase PF00910.22 ETS85040.1 - 0.031 14.7 0.0 0.081 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 ETS85040.1 - 0.044 14.2 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 ETS85040.1 - 0.081 13.4 0.1 0.76 10.3 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 ETS85040.1 - 0.098 12.4 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pectate_lyase PF03211.13 ETS85042.1 - 1.1e-83 279.8 12.8 3.8e-42 144.1 6.2 2.0 1 1 1 2 2 2 2 Pectate lyase Acetyltransf_10 PF13673.7 ETS85043.1 - 6.6e-09 35.8 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS85043.1 - 1.7e-05 25.0 0.0 3.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS85043.1 - 2.8e-05 24.4 0.0 4.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETS85043.1 - 0.00014 21.9 0.0 0.0017 18.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS85043.1 - 0.00074 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein DUF2613 PF11021.8 ETS85043.1 - 0.12 12.5 0.4 0.23 11.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) GNAT_acetyltran PF12746.7 ETS85043.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Tyrosinase PF00264.20 ETS85044.1 - 1.2e-27 97.6 6.9 5.4e-27 95.5 3.6 2.4 2 1 0 2 2 2 1 Common central domain of tyrosinase Glyco_hydro_3_C PF01915.22 ETS85045.1 - 7.9e-43 146.8 0.4 2.4e-42 145.2 0.4 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS85045.1 - 3.8e-35 121.8 0.0 1.1e-34 120.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS85045.1 - 6.8e-27 93.4 0.2 1.3e-26 92.5 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain TetM_leader PF08076.11 ETS85045.1 - 0.15 11.9 0.2 0.33 10.8 0.2 1.6 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide MFS_1 PF07690.16 ETS85046.1 - 2.4e-28 99.1 32.5 3.1e-28 98.7 32.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PMSR PF01625.21 ETS85047.1 - 6.4e-62 208.3 0.5 7.7e-62 208.0 0.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Bax1-I PF01027.20 ETS85048.1 - 1.1e-35 123.4 10.2 1.9e-35 122.6 10.2 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 cNMP_binding PF00027.29 ETS85049.1 - 1.8e-34 117.7 0.0 1.3e-19 70.0 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain cNMPbd_u2 PF16643.5 ETS85049.1 - 6.5e-32 111.2 13.0 1.5e-31 110.0 13.0 1.6 1 0 0 1 1 1 1 Unstructured region on cNMP-binding protein LRR_6 PF13516.6 ETS85049.1 - 2.6e-08 33.2 11.6 0.11 12.7 0.0 7.3 9 0 0 9 9 9 2 Leucine Rich repeat LRR_4 PF12799.7 ETS85049.1 - 2.5e-07 30.9 0.1 0.077 13.5 0.3 4.8 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ETS85049.1 - 0.0017 18.2 2.7 0.0017 18.2 2.7 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ETS85049.1 - 0.0021 17.9 2.2 0.0021 17.9 2.2 2.7 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 ETS85049.1 - 0.0026 18.1 6.1 20 6.3 0.0 6.4 8 1 0 8 8 8 1 Leucine Rich Repeat ADH_zinc_N PF00107.26 ETS85050.1 - 1.8e-27 95.9 0.6 4.2e-27 94.7 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS85050.1 - 2.3e-22 80.5 0.0 5.3e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS85050.1 - 1e-07 31.8 0.9 2.4e-07 30.6 0.9 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS85051.1 - 1.8e-16 60.3 0.0 3.1e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS85051.1 - 1.4e-10 42.4 0.0 2.6e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS85051.1 - 8.9e-06 25.6 0.0 0.00027 20.8 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF938 PF06080.12 ETS85051.1 - 0.014 15.2 0.0 0.051 13.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Fungal_trans PF04082.18 ETS85052.1 - 5.8e-18 64.9 0.1 1e-17 64.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS85052.1 - 2e-08 34.2 11.3 3.6e-08 33.4 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 ETS85053.1 - 1e-31 109.9 0.0 1.3e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS85053.1 - 1.6e-26 93.3 0.1 1.6e-25 90.1 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS85053.1 - 1.1e-06 28.8 0.3 2.1e-06 27.8 0.3 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS85053.1 - 0.053 12.6 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ThiF PF00899.21 ETS85053.1 - 0.24 10.7 1.5 0.3 10.4 0.4 1.6 1 1 1 2 2 2 0 ThiF family XLF PF09302.11 ETS85055.1 - 1.2e-46 159.1 0.0 2e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component PET10 PF17316.2 ETS85055.1 - 0.075 12.5 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Petite colonies protein 10 Cupin_5 PF06172.11 ETS85057.1 - 8.9e-39 132.9 0.2 1.9e-38 131.8 0.2 1.5 1 1 0 1 1 1 1 Cupin superfamily (DUF985) Forkhead PF00250.18 ETS85058.1 - 1.5e-20 73.2 0.0 2.4e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain Cactin_mid PF10312.9 ETS85059.1 - 4.2e-64 215.9 2.1 6.2e-64 215.4 2.1 1.3 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 ETS85059.1 - 1e-50 170.8 2.0 1.8e-50 170.0 2.0 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 ETS85059.1 - 0.012 15.9 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) Mucin-like PF16058.5 ETS85059.1 - 0.021 14.9 1.3 0.021 14.9 1.3 2.3 2 0 0 2 2 2 0 Mucin-like FAM199X PF15814.5 ETS85059.1 - 0.34 9.9 3.8 0.56 9.2 3.8 1.3 1 0 0 1 1 1 0 Protein family FAM199X FlgN PF05130.12 ETS85059.1 - 0.56 10.7 4.2 1.7 9.2 1.4 2.3 2 0 0 2 2 2 0 FlgN protein Med3 PF11593.8 ETS85059.1 - 0.87 8.7 5.8 1.4 8.0 5.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Hce2 PF14856.6 ETS85060.1 - 9.5e-10 38.7 0.0 1.4e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor mRNA_stabil PF13929.6 ETS85060.1 - 0.17 10.9 0.0 0.4 9.6 0.0 1.5 2 0 0 2 2 2 0 mRNA stabilisation CFEM PF05730.11 ETS85061.1 - 1.5e-07 31.4 10.4 4e-07 30.0 10.4 1.8 1 0 0 1 1 1 1 CFEM domain Macoilin PF09726.9 ETS85061.1 - 0.07 11.7 3.9 0.082 11.5 3.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF347 PF03988.12 ETS85061.1 - 0.34 11.1 2.3 0.33 11.2 0.2 2.1 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Apt1 PF10351.9 ETS85061.1 - 1.5 7.6 3.9 1.6 7.5 3.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Endomucin PF07010.12 ETS85061.1 - 1.6 8.7 33.2 2.8 7.8 33.2 1.3 1 0 0 1 1 1 0 Endomucin CDC27 PF09507.10 ETS85061.1 - 5.5 6.3 20.1 8.1 5.7 20.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.13 ETS85061.1 - 6.5 6.6 10.5 8.1 6.3 10.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 ETS85061.1 - 6.7 5.3 10.2 7.9 5.0 10.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hamartin PF04388.12 ETS85061.1 - 8.8 4.9 14.5 12 4.4 14.5 1.2 1 0 0 1 1 1 0 Hamartin protein ACOX PF01756.19 ETS85063.1 - 4.7e-46 156.6 0.3 1.5e-45 155.0 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 ETS85063.1 - 6.6e-28 97.8 0.6 1.3e-27 96.8 0.6 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 ETS85063.1 - 4.2e-12 46.1 0.0 2.3e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ETS85063.1 - 6.4e-05 23.2 0.7 0.0092 16.2 0.7 2.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ribosomal_L19e PF01280.20 ETS85064.1 - 1.5e-33 115.8 7.3 1.5e-33 115.8 7.3 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e TRAP-gamma PF07074.12 ETS85064.1 - 1.3 8.6 3.5 1.8 8.1 3.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF3043 PF11241.8 ETS85064.1 - 7.9 6.5 12.9 17 5.4 12.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) AA_permease PF00324.21 ETS85065.1 - 3e-107 359.2 42.2 3.6e-107 358.9 42.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS85065.1 - 1.9e-26 92.8 44.3 2.3e-26 92.6 44.3 1.0 1 0 0 1 1 1 1 Amino acid permease ubiquitin PF00240.23 ETS85066.1 - 6.2e-20 70.7 0.0 1.8e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ETS85066.1 - 1.6e-07 31.0 0.0 3.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 ETS85066.1 - 0.064 13.4 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Copper-fist PF00649.18 ETS85068.1 - 1.9e-18 65.6 0.6 1.9e-18 65.6 0.6 1.9 2 0 0 2 2 2 1 Copper fist DNA binding domain SHMT PF00464.19 ETS85070.1 - 7.8e-195 647.1 0.1 9.7e-195 646.8 0.1 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.19 ETS85070.1 - 0.03 13.3 0.1 0.05 12.6 0.1 1.4 1 1 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ETS85070.1 - 0.075 12.3 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family FTA2 PF13095.6 ETS85071.1 - 5.2e-45 153.7 0.0 7.7e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Mvb12 PF09452.10 ETS85073.1 - 0.045 14.2 0.5 0.088 13.2 0.5 1.5 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 Hydrolase_6 PF13344.6 ETS85074.1 - 1.5e-24 86.0 0.0 2.6e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ETS85074.1 - 5.7e-14 51.9 0.0 2.4e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 ETS85074.1 - 0.052 13.8 0.0 5.5 7.2 0.0 2.7 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase adh_short_C2 PF13561.6 ETS85075.1 - 8.7e-53 179.3 0.0 1.2e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS85075.1 - 2.9e-40 137.8 0.0 4.9e-40 137.1 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS85075.1 - 4e-10 39.9 0.1 5.8e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 KR domain MR_MLE_C PF13378.6 ETS85076.1 - 2.2e-41 141.9 0.0 2.8e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ETS85076.1 - 9.9e-10 38.7 0.0 1.6e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fungal_trans PF04082.18 ETS85078.1 - 7.6e-23 80.9 1.0 1.3e-22 80.2 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS85078.1 - 4.9e-07 29.8 14.2 8.3e-07 29.0 14.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 ETS85079.1 - 2.3e-24 85.4 1.4 5e-24 84.3 1.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS85079.1 - 9.3e-10 38.6 0.4 1.5e-05 24.9 0.0 3.1 3 0 0 3 3 3 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 ETS85079.1 - 8.9e-09 35.1 0.2 1.8e-08 34.1 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated RRM_1 PF00076.22 ETS85080.1 - 5.5e-50 167.1 0.5 2.5e-16 59.2 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ETS85080.1 - 1.9e-35 120.6 1.7 1.9e-27 94.9 0.0 4.4 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_5 PF13893.6 ETS85080.1 - 1.5e-08 34.3 0.1 0.00021 20.9 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ETS85080.1 - 5.5e-05 23.1 0.0 0.052 13.5 0.1 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Methyltransf_2 PF00891.18 ETS85081.1 - 1.7e-25 89.6 0.0 2.4e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain HTH_IclR PF09339.10 ETS85081.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain SKG6 PF08693.10 ETS85082.1 - 0.0023 17.3 0.5 0.0045 16.4 0.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain GAS PF13851.6 ETS85083.1 - 0.00051 19.5 8.9 0.00097 18.5 8.9 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DivIC PF04977.15 ETS85083.1 - 0.011 15.5 5.6 0.43 10.4 0.7 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF848 PF05852.11 ETS85083.1 - 0.038 14.1 6.0 0.08 13.1 6.0 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) TMF_DNA_bd PF12329.8 ETS85083.1 - 0.062 13.3 6.4 0.034 14.2 3.5 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF1515 PF07439.11 ETS85083.1 - 0.14 12.2 1.8 0.34 10.9 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Macoilin PF09726.9 ETS85083.1 - 0.2 10.2 8.1 0.26 9.8 8.1 1.2 1 0 0 1 1 1 0 Macoilin family BST2 PF16716.5 ETS85083.1 - 0.21 12.2 10.0 0.65 10.6 7.3 2.9 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DMPK_coil PF08826.10 ETS85083.1 - 0.25 11.5 10.7 0.2 11.8 6.3 2.6 1 1 1 2 2 2 0 DMPK coiled coil domain like V_ATPase_I PF01496.19 ETS85083.1 - 0.3 9.0 7.3 0.48 8.3 7.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BLOC1_2 PF10046.9 ETS85083.1 - 0.59 10.5 6.1 1.5 9.2 5.9 1.8 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup54 PF13874.6 ETS85083.1 - 0.77 9.9 8.7 2.1 8.4 8.7 1.7 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ADIP PF11559.8 ETS85083.1 - 0.8 9.8 11.9 0.068 13.3 5.7 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2570 PF10828.8 ETS85083.1 - 2 8.3 6.7 4.8 7.0 6.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) FlaC_arch PF05377.11 ETS85083.1 - 2.2 8.7 6.0 4.2 7.8 0.9 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 ETS85083.1 - 2.4 7.3 6.5 3.6 6.7 6.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein Cnn_1N PF07989.11 ETS85083.1 - 2.9 8.1 9.8 5.8 7.2 1.8 2.8 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 JIP_LZII PF16471.5 ETS85083.1 - 4 7.7 10.6 0.76 10.0 2.5 2.7 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II JAKMIP_CC3 PF16034.5 ETS85083.1 - 6.3 6.7 17.0 3.5 7.5 12.9 2.4 2 1 0 2 2 2 0 JAKMIP CC3 domain p450 PF00067.22 ETS85084.1 - 1.2e-63 215.5 0.0 1.5e-63 215.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NACHT PF05729.12 ETS85085.1 - 1.8e-11 44.2 1.4 4.5e-11 43.0 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 ETS85085.1 - 3.2e-06 27.5 0.0 2.5e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS85085.1 - 4.5e-05 23.9 2.3 8.2e-05 23.1 0.0 2.6 4 0 0 4 4 2 1 AAA ATPase domain ATPase_2 PF01637.18 ETS85085.1 - 0.00038 20.4 0.0 0.0013 18.7 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 ETS85085.1 - 0.00048 20.5 0.0 0.0015 18.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 ETS85085.1 - 0.002 18.3 0.2 0.16 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain ETC_C1_NDUFA4 PF04800.12 ETS85085.1 - 0.0049 17.1 0.2 0.013 15.7 0.2 1.7 1 0 0 1 1 1 1 ETC complex I subunit conserved region AAA_18 PF13238.6 ETS85085.1 - 0.0056 17.2 0.0 0.033 14.7 0.0 2.4 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 ETS85085.1 - 0.02 15.4 0.1 0.2 12.2 0.0 2.5 1 1 0 2 2 2 0 ABC transporter DUF87 PF01935.17 ETS85085.1 - 0.022 14.8 0.1 0.24 11.5 0.0 2.4 2 1 0 2 2 2 0 Helicase HerA, central domain AAA PF00004.29 ETS85085.1 - 0.03 14.7 0.0 0.19 12.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 ETS85085.1 - 0.036 14.0 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 ETS85085.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ABC_tran_CTD PF16326.5 ETS85085.1 - 0.082 13.2 0.2 0.51 10.6 0.3 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain GP52 PF17468.2 ETS85085.1 - 0.13 12.4 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Phage gene product 52 MMR_HSR1 PF01926.23 ETS85085.1 - 0.13 12.3 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 ETS85085.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ETS85085.1 - 0.16 11.2 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin HMMR_C PF15908.5 ETS85085.1 - 0.16 12.2 1.4 0.31 11.3 1.4 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal AAA_23 PF13476.6 ETS85085.1 - 0.2 12.2 0.8 27 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhaP_Bmeg PF09602.10 ETS85085.1 - 0.45 10.4 3.5 1 9.3 3.5 1.5 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Shikimate_dh_N PF08501.11 ETS85086.1 - 3.4e-22 78.5 0.0 7.6e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 ETS85086.1 - 6.2e-08 32.3 0.2 1.2e-07 31.3 0.2 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 ETS85086.1 - 0.03 14.4 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CoA_transf_3 PF02515.17 ETS85087.1 - 1.8e-45 155.7 0.0 4.5e-43 147.8 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III SnoaL_3 PF13474.6 ETS85087.1 - 0.23 11.7 0.9 0.94 9.7 0.1 2.4 3 0 0 3 3 3 0 SnoaL-like domain AtuA PF07287.11 ETS85088.1 - 6.8e-134 446.0 0.0 8.6e-134 445.7 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Thioredoxin PF00085.20 ETS85089.1 - 9.3e-12 44.8 0.1 2.7e-09 36.9 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ETS85089.1 - 0.083 13.2 0.1 0.94 9.9 0.2 2.4 2 1 0 2 2 2 0 Thioredoxin-like GST_N_3 PF13417.6 ETS85089.1 - 0.54 10.7 2.3 2.3 8.7 0.0 3.0 4 1 0 4 4 4 0 Glutathione S-transferase, N-terminal domain Fungal_trans PF04082.18 ETS85090.1 - 7.8e-05 21.8 0.0 0.00019 20.5 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.23 ETS85091.1 - 7e-69 232.6 0.0 8.8e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 ETS85091.1 - 0.00041 20.0 0.0 0.0094 15.6 0.0 2.4 3 0 0 3 3 3 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.12 ETS85091.1 - 0.19 10.7 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Sugar_tr PF00083.24 ETS85092.1 - 1.4e-89 301.0 19.9 1.7e-89 300.7 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS85092.1 - 8e-22 77.6 31.2 3.6e-13 49.2 10.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily IncE PF17627.2 ETS85092.1 - 0.87 9.6 3.7 3.5 7.7 3.0 2.2 2 0 0 2 2 2 0 Inclusion membrane protein E Amino_oxidase PF01593.24 ETS85093.1 - 8.4e-45 153.9 0.2 1.8e-44 152.8 0.2 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ETS85093.1 - 4.2e-14 52.5 0.3 1.2e-13 51.1 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS85093.1 - 9.5e-08 32.0 0.8 1.1e-06 28.5 0.7 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS85093.1 - 8.9e-06 25.1 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS85093.1 - 1.7e-05 24.1 1.0 2.4e-05 23.6 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ETS85093.1 - 4e-05 23.2 0.3 6.5e-05 22.5 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS85093.1 - 5.7e-05 22.0 0.1 8.9e-05 21.4 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 ETS85093.1 - 6.7e-05 23.4 0.1 0.00015 22.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS85093.1 - 0.00021 20.6 0.1 0.00033 20.0 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 ETS85093.1 - 0.00049 19.4 0.1 0.00076 18.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ETS85093.1 - 0.012 14.7 0.4 0.021 13.9 0.4 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 ETS85093.1 - 0.013 14.6 0.1 0.021 13.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 ETS85093.1 - 0.022 14.7 0.3 0.58 10.1 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding GDI PF00996.18 ETS85093.1 - 0.059 11.9 0.0 0.12 10.9 0.0 1.4 2 0 0 2 2 2 0 GDP dissociation inhibitor Pyr_redox_3 PF13738.6 ETS85093.1 - 0.1 11.9 0.2 3 7.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.11 ETS85094.1 - 6.5e-30 104.4 0.3 1.1e-29 103.6 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.29 ETS85096.1 - 1.7e-19 70.6 0.0 2.8e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS85096.1 - 1.1e-05 25.8 0.2 0.00053 20.4 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS85096.1 - 0.0003 21.1 0.2 0.048 13.9 0.1 2.6 1 1 0 2 2 2 1 AAA domain CPT PF07931.12 ETS85096.1 - 0.036 13.9 0.2 0.085 12.7 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein RuvB_N PF05496.12 ETS85096.1 - 0.045 13.5 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ETS85096.1 - 0.062 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ETS85096.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ETS85096.1 - 0.15 11.3 0.1 1.2 8.3 0.1 2.1 2 0 0 2 2 2 0 NB-ARC domain ARID PF01388.21 ETS85097.1 - 4.5e-16 59.3 1.6 8e-16 58.5 0.0 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 ETS85097.1 - 0.43 9.8 6.2 0.43 9.8 0.0 2.9 2 1 1 3 3 3 0 SWI/SNF-like complex subunit BAF250/Osa DcrB PF08786.11 ETS85097.1 - 6 7.0 16.0 1.6e+02 2.4 16.8 2.5 2 0 0 2 2 2 0 DcrB VIR_N PF15912.5 ETS85098.1 - 0.00029 20.5 5.3 0.00042 20.0 5.3 1.2 1 0 0 1 1 1 1 Virilizer, N-terminal SKG6 PF08693.10 ETS85098.1 - 0.00041 19.7 1.6 0.00041 19.7 1.6 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain CAP_N PF01213.19 ETS85098.1 - 0.0095 15.5 5.0 0.0095 15.5 5.0 2.3 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 ETS85098.1 - 6.3 6.8 12.8 0.59 10.2 1.5 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator HATPase_c PF02518.26 ETS85099.1 - 8.8e-23 81.0 0.0 1.7e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ETS85099.1 - 2.3e-21 76.0 2.5 8.6e-15 54.9 0.1 3.2 3 0 0 3 3 3 2 Response regulator receiver domain PAS_4 PF08448.10 ETS85099.1 - 2.2e-13 50.4 0.0 1.6e-08 34.8 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 ETS85099.1 - 2.9e-11 43.5 3.2 1.2e-05 25.5 0.2 4.0 3 1 0 3 3 3 2 PAS fold PAS PF00989.25 ETS85099.1 - 5.9e-09 35.9 0.0 2.6e-06 27.4 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 ETS85099.1 - 1.7e-08 34.6 0.0 0.00036 20.7 0.0 2.9 2 1 0 2 2 2 2 PAS domain HisKA PF00512.25 ETS85099.1 - 1.6e-07 31.2 0.0 5.7e-07 29.5 0.0 2.0 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 ETS85099.1 - 0.017 15.1 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 PAS domain STAG PF08514.11 ETS85099.1 - 0.18 11.7 0.3 0.45 10.4 0.3 1.6 1 0 0 1 1 1 0 STAG domain Flavokinase PF01687.17 ETS85100.1 - 8e-13 48.7 0.0 1.5e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Riboflavin kinase APG17 PF04108.12 ETS85101.1 - 5.2e-134 447.3 13.3 6e-134 447.1 13.3 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Gp-FAR-1 PF05823.12 ETS85101.1 - 0.00027 21.3 0.2 0.092 13.1 0.1 2.8 2 1 0 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) LOH1CR12 PF10158.9 ETS85101.1 - 0.0021 18.1 3.5 0.041 13.9 0.3 3.2 3 0 0 3 3 3 1 Tumour suppressor protein RmuC PF02646.16 ETS85101.1 - 0.04 13.0 0.3 0.04 13.0 0.3 3.4 4 2 0 4 4 4 0 RmuC family GAT PF03127.14 ETS85101.1 - 0.052 13.8 7.1 0.24 11.7 1.4 3.6 3 0 0 3 3 3 0 GAT domain BLOC1_2 PF10046.9 ETS85101.1 - 0.071 13.4 4.9 0.41 11.0 0.8 3.6 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HJURP_mid PF12346.8 ETS85101.1 - 0.16 12.4 0.8 4.8 7.7 0.2 2.8 2 1 0 2 2 2 0 Holliday junction recognition protein-associated repeat Laminin_II PF06009.12 ETS85101.1 - 0.29 11.1 8.9 0.23 11.5 0.7 3.5 3 1 0 4 4 4 0 Laminin Domain II DUF1722 PF08349.11 ETS85101.1 - 0.37 11.1 1.9 9.2 6.6 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1722) Troponin PF00992.20 ETS85101.1 - 0.95 9.8 6.2 0.16 12.2 0.9 2.4 3 0 0 3 3 2 0 Troponin Cep57_MT_bd PF06657.13 ETS85101.1 - 0.99 9.9 7.8 2.4 8.7 0.3 3.8 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 KxDL PF10241.9 ETS85101.1 - 2.8 8.3 6.6 14 6.0 0.3 3.5 3 0 0 3 3 3 0 Uncharacterized conserved protein DUF5082 PF16888.5 ETS85101.1 - 4.2 7.7 7.9 27 5.0 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF5082) YabA PF06156.13 ETS85101.1 - 4.2 8.1 7.0 21 5.8 0.8 3.7 2 2 1 3 3 3 0 Initiation control protein YabA V_ATPase_I PF01496.19 ETS85101.1 - 6.6 4.5 7.2 4.4 5.1 2.1 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Sec34 PF04136.15 ETS85101.1 - 7.2 6.5 9.8 0.2 11.6 0.7 3.0 4 1 0 4 4 4 0 Sec34-like family WXG100 PF06013.12 ETS85101.1 - 9 6.6 11.2 7.5 6.9 0.8 4.7 3 2 1 4 4 4 0 Proteins of 100 residues with WXG DUF4795 PF16043.5 ETS85102.1 - 0.0099 15.5 19.7 0.52 9.9 1.3 3.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) SelB-wing_1 PF09105.10 ETS85102.1 - 0.015 15.2 2.8 0.73 9.8 1.1 2.8 2 0 0 2 2 2 0 Elongation factor SelB, winged helix BatA PF07584.11 ETS85102.1 - 0.043 14.2 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Lectin_N PF03954.14 ETS85102.1 - 0.096 12.4 7.7 0.87 9.3 1.0 3.3 2 2 1 3 3 3 0 Hepatic lectin, N-terminal domain Raco_middle PF17651.1 ETS85102.1 - 0.1 12.3 0.4 0.22 11.2 0.4 1.5 1 0 0 1 1 1 0 RACo middle region DUF1664 PF07889.12 ETS85102.1 - 0.21 11.6 13.8 0.26 11.3 2.5 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) BDV_P24 PF06595.11 ETS85102.1 - 0.27 11.1 7.8 0.35 10.7 0.8 2.4 1 1 1 2 2 2 0 Borna disease virus P24 protein DUF1949 PF09186.11 ETS85102.1 - 0.47 10.4 3.4 1.9 8.4 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1949) TRAF_BIRC3_bd PF16673.5 ETS85102.1 - 1.1 9.1 13.1 0.8 9.5 1.0 4.4 3 1 0 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain Fib_alpha PF08702.10 ETS85102.1 - 1.2 9.3 17.7 0.42 10.8 2.0 3.5 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family ABC_tran PF00005.27 ETS85102.1 - 1.2 9.6 8.4 2.6 8.6 0.2 2.6 1 1 1 2 2 2 0 ABC transporter DUF4988 PF16378.5 ETS85102.1 - 1.4 8.6 7.5 16 5.1 1.2 3.8 1 1 1 3 3 3 0 Domain of unknown function AAA_13 PF13166.6 ETS85102.1 - 2.1 6.9 19.9 0.42 9.2 14.7 1.7 1 1 1 2 2 2 0 AAA domain BLOC1_2 PF10046.9 ETS85102.1 - 2.7 8.4 11.2 0.72 10.2 1.2 3.7 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PKcGMP_CC PF16808.5 ETS85102.1 - 4.3 7.3 6.2 2.4 8.1 1.0 3.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Matrilin_ccoil PF10393.9 ETS85102.1 - 7 6.6 14.0 1.2 9.0 0.2 4.9 4 1 1 5 5 5 0 Trimeric coiled-coil oligomerisation domain of matrilin XhlA PF10779.9 ETS85102.1 - 9.4 6.5 12.3 5.9 7.2 0.4 3.8 3 1 0 3 3 3 0 Haemolysin XhlA AMP-binding PF00501.28 ETS85103.1 - 1.6e-60 204.9 0.0 3.3e-60 203.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 ETS85103.1 - 9.9e-14 51.5 0.0 2.5e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 ETS85103.1 - 6.7e-07 28.8 13.8 0.0055 16.4 0.1 7.1 8 0 0 8 8 8 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ETS85103.1 - 0.014 15.1 11.2 3.6 7.4 0.0 6.3 5 2 1 6 6 6 0 Hexapeptide repeat of succinyl-transferase DUF4129 PF13559.6 ETS85103.1 - 0.11 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) Pap_E4 PF02711.14 ETS85105.1 - 3.1 8.8 6.9 33 5.5 0.1 2.4 2 0 0 2 2 2 0 E4 protein Mpv17_PMP22 PF04117.12 ETS85106.1 - 1e-15 57.7 0.1 2.3e-15 56.6 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.16 ETS85107.1 - 2.1e-40 138.8 31.9 4.9e-40 137.5 30.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 ETS85107.1 - 0.0045 17.3 0.0 0.0045 17.3 0.0 3.6 3 2 1 4 4 4 1 Domain of unknown function (DUF1772) Aldo_ket_red PF00248.21 ETS85108.1 - 3.9e-50 170.7 0.0 4.5e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_108 PF05838.12 ETS85108.1 - 0.076 13.5 0.1 8.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Glycosyl hydrolase 108 Ribosomal_L12_N PF16320.5 ETS85108.1 - 0.098 12.4 0.3 4 7.2 0.1 2.9 3 1 0 3 3 3 0 Ribosomal protein L7/L12 dimerisation domain HTH_22 PF13309.6 ETS85108.1 - 0.14 12.3 0.0 7.4 6.7 0.0 2.4 2 0 0 2 2 2 0 HTH domain PseudoU_synth_1 PF01416.20 ETS85109.1 - 5.6e-12 46.1 0.0 4e-10 40.1 0.0 2.6 2 0 0 2 2 2 1 tRNA pseudouridine synthase Ndc80_HEC PF03801.13 ETS85109.1 - 0.039 13.6 0.2 0.082 12.5 0.2 1.4 1 0 0 1 1 1 0 HEC/Ndc80p family Mucin PF01456.17 ETS85109.1 - 9.6 6.2 11.4 19 5.2 11.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Med22 PF06179.12 ETS85110.1 - 1e-14 54.6 0.6 1.2e-14 54.3 0.6 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Pyr_redox_2 PF07992.14 ETS85111.1 - 2.5e-36 125.4 0.0 3.2e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS85111.1 - 2.7e-13 50.3 0.0 4e-10 40.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS85111.1 - 1.7e-06 27.5 0.1 0.00018 20.8 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ETS85111.1 - 0.011 15.0 0.0 0.073 12.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS85111.1 - 0.046 13.7 1.0 20 5.1 0.0 3.7 3 1 0 4 4 4 0 FAD-NAD(P)-binding TrkA_N PF02254.18 ETS85111.1 - 0.096 13.0 0.0 17 5.7 0.0 2.9 3 0 0 3 3 3 0 TrkA-N domain DinI PF06183.13 ETS85111.1 - 0.098 13.0 0.1 3.9 7.9 0.0 2.5 1 1 1 2 2 2 0 DinI-like family Lycopene_cycl PF05834.12 ETS85111.1 - 0.12 11.5 0.0 12 4.8 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 ETS85111.1 - 0.13 12.5 0.0 9.4 6.5 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ETS85111.1 - 0.51 9.1 2.8 5.2 5.8 0.0 3.0 3 1 1 4 4 4 0 Tryptophan halogenase Cerato-platanin PF07249.12 ETS85112.1 - 1.1e-06 28.8 0.3 5.2e-06 26.6 0.3 2.2 1 0 0 1 1 1 1 Cerato-platanin GREB1 PF15782.5 ETS85112.1 - 0.88 6.6 18.9 1.1 6.3 18.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer adh_short PF00106.25 ETS85113.1 - 5.2e-07 29.3 0.3 5.4e-07 29.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS85113.1 - 0.0009 18.9 0.3 0.0009 18.9 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Aldolase PF01081.19 ETS85113.1 - 0.009 15.4 0.3 0.011 15.2 0.3 1.1 1 0 0 1 1 1 1 KDPG and KHG aldolase DUF2173 PF09941.9 ETS85113.1 - 0.031 14.6 0.7 0.041 14.2 0.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) Methyltransf_11 PF08241.12 ETS85113.1 - 0.055 14.1 0.0 0.063 13.9 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_7 PF13241.6 ETS85113.1 - 0.097 13.1 0.3 0.13 12.7 0.3 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding UbiA PF01040.18 ETS85114.1 - 1.4e-19 70.4 18.0 6.3e-19 68.3 16.6 1.9 1 1 1 2 2 2 1 UbiA prenyltransferase family Zn_clus PF00172.18 ETS85115.1 - 9.4e-11 41.7 5.8 2.2e-10 40.5 5.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M20 PF01546.28 ETS85116.1 - 1.3e-07 31.6 0.3 2.1e-07 30.8 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ETS85116.1 - 2.7e-06 27.3 0.0 6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain APH PF01636.23 ETS85118.1 - 2e-14 54.1 0.0 3.1e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETS85118.1 - 4.4e-05 23.2 0.0 9.3e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 ETS85118.1 - 0.013 15.1 0.0 0.03 13.9 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Haspin_kinase PF12330.8 ETS85118.1 - 0.037 13.0 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 ETS85118.1 - 0.044 13.1 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Fructosamin_kin PF03881.14 ETS85118.1 - 0.062 12.5 0.1 6 6.0 0.1 2.1 2 0 0 2 2 2 0 Fructosamine kinase EcKinase PF02958.20 ETS85118.1 - 0.094 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 ETS85118.1 - 0.21 10.4 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) ADH_zinc_N PF00107.26 ETS85120.1 - 4e-25 88.3 1.0 7e-25 87.5 1.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS85120.1 - 7.1e-22 77.4 0.5 1.5e-21 76.3 0.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ETS85120.1 - 5.5e-07 30.7 0.0 1.4e-06 29.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CsiV PF10972.8 ETS85121.1 - 0.069 12.9 0.8 0.084 12.6 0.8 1.1 1 0 0 1 1 1 0 Peptidoglycan-binding protein, CsiV Tricorn_C1 PF14684.6 ETS85122.1 - 0.09 12.9 0.2 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease C1 domain Glyco_transf_28 PF03033.20 ETS85123.1 - 1.1e-22 80.5 0.0 2.4e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 ETS85123.1 - 0.0005 19.0 0.0 0.00083 18.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 ETS85123.1 - 0.0012 19.1 1.1 0.011 16.1 0.1 2.9 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain MARVEL PF01284.23 ETS85124.1 - 0.0021 18.1 11.1 0.0021 18.1 11.1 2.0 1 1 1 2 2 2 2 Membrane-associating domain Bac_rhamnosid6H PF17389.2 ETS85125.1 - 4.1e-08 32.9 0.3 1.2e-07 31.4 0.1 1.7 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_36 PF17167.4 ETS85125.1 - 0.00092 18.0 0.0 0.0014 17.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Bac_rhamnosid_C PF17390.2 ETS85125.1 - 0.001 18.8 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 ETS85125.1 - 0.0011 17.9 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid PF05592.11 ETS85125.1 - 0.024 14.6 0.0 0.063 13.3 0.0 1.7 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain AflR PF08493.10 ETS85126.1 - 4.3e-09 36.3 13.6 1.4e-08 34.6 13.6 1.9 1 1 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 ETS85126.1 - 1.1e-07 31.8 10.9 3.2e-07 30.4 10.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_28 PF00295.17 ETS85127.1 - 5.2e-23 81.6 10.6 7.2e-23 81.2 10.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF5613 PF18467.1 ETS85128.1 - 0.064 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5613) Sugar_tr PF00083.24 ETS85129.1 - 4.6e-68 230.1 15.9 5.2e-68 229.9 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2985 PF11204.8 ETS85129.1 - 0.0073 16.4 2.5 1.1 9.5 0.3 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2985) DUF4381 PF14316.6 ETS85129.1 - 0.07 13.4 0.5 0.92 9.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DUF4131 PF13567.6 ETS85129.1 - 3.8 7.1 10.7 0.84 9.3 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) HCO3_cotransp PF00955.21 ETS85130.1 - 1.5e-75 255.0 14.4 1.3e-41 143.0 8.0 2.1 1 1 1 2 2 2 2 HCO3- transporter family Sulfate_transp PF00916.20 ETS85130.1 - 0.0087 14.9 14.8 0.24 10.1 9.7 3.1 2 1 0 2 2 2 2 Sulfate permease family HET PF06985.11 ETS85132.1 - 2.8e-32 112.1 2.4 4.1e-32 111.5 2.4 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ETS85133.1 - 8.9e-29 100.7 0.0 1.4e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Linker_histone PF00538.19 ETS85134.1 - 2.4e-09 37.4 0.0 7.9e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 linker histone H1 and H5 family HC2 PF07382.11 ETS85134.1 - 0.16 12.0 74.3 0.21 11.7 74.3 1.1 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Gti1_Pac2 PF09729.9 ETS85136.1 - 5.3e-44 150.5 3.2 5e-37 127.7 0.3 2.4 1 1 1 2 2 2 2 Gti1/Pac2 family tRNA-synt_2 PF00152.20 ETS85137.1 - 1.3e-81 274.1 0.0 1.7e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ETS85137.1 - 3.1e-05 23.9 0.0 5.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.25 ETS85137.1 - 0.053 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) DUF2263 PF10021.9 ETS85138.1 - 4e-09 37.0 0.0 5.9e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) SR-25 PF10500.9 ETS85138.1 - 1.3 8.6 12.6 1.8 8.1 12.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sec23_trunk PF04811.15 ETS85139.1 - 1.7e-51 175.2 0.0 2.7e-51 174.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 ETS85139.1 - 1.3e-24 85.9 0.0 3e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 ETS85139.1 - 1.3e-16 61.1 0.0 3.4e-16 59.7 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 ETS85139.1 - 5.4e-06 26.2 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 ETS85139.1 - 0.00088 19.3 0.1 0.0023 18.0 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger DUF1678 PF07913.11 ETS85139.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) Lactamase_B_6 PF16661.5 ETS85141.1 - 7.2e-62 208.3 0.0 1.1e-61 207.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 ETS85141.1 - 8.8e-25 87.8 9.5 1.2e-20 74.4 0.0 3.4 3 1 1 4 4 4 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 ETS85141.1 - 6e-18 65.1 0.0 1.4e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 ETS85141.1 - 3.4e-09 36.5 0.0 7.2e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 ETS85141.1 - 0.03 13.8 0.1 0.074 12.6 0.1 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DUF1541 PF07563.11 ETS85141.1 - 0.11 12.4 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1541) Glyco_hydro_43 PF04616.14 ETS85142.1 - 9.1e-12 44.9 2.9 9.1e-12 44.9 2.9 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 PilJ_C PF18223.1 ETS85142.1 - 8.5 6.9 7.5 40 4.8 0.3 3.5 3 1 1 4 4 4 0 Pili PilJ C-terminal domain Methyltransf_23 PF13489.6 ETS85143.1 - 8.7e-20 71.2 0.0 1.2e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS85143.1 - 7.3e-10 38.8 0.0 3.6e-09 36.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS85143.1 - 1.5e-09 38.4 0.0 3.7e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS85143.1 - 1.9e-06 28.4 0.0 3.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS85143.1 - 6.1e-05 23.7 0.0 0.00014 22.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS85143.1 - 0.0018 17.7 0.0 0.0073 15.7 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 ETS85143.1 - 0.028 14.2 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 ETS85143.1 - 0.028 13.9 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase PCMT PF01135.19 ETS85143.1 - 0.085 12.6 0.0 0.55 10.0 0.0 2.2 2 1 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 ETS85143.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ank_2 PF12796.7 ETS85144.1 - 3.9e-08 33.8 0.0 0.00046 20.7 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS85144.1 - 1.2e-05 25.8 0.1 0.011 16.3 0.0 3.7 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS85144.1 - 0.00011 22.4 0.0 0.00097 19.4 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS85144.1 - 0.00036 20.8 1.1 0.012 16.1 0.0 3.9 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 ETS85144.1 - 0.0019 18.6 0.0 0.17 12.4 0.0 3.8 5 0 0 5 5 5 1 Ankyrin repeat AAA_12 PF13087.6 ETS85145.1 - 7e-20 71.5 0.0 1.1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ETS85145.1 - 7.8e-09 35.7 3.2 4e-08 33.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ETS85145.1 - 1.5e-06 28.1 0.1 0.0027 17.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 ETS85145.1 - 0.00023 21.5 0.0 0.0015 18.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 ETS85145.1 - 0.00035 20.4 0.0 1.3 8.7 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase SOG2 PF10428.9 ETS85145.1 - 0.23 10.6 7.1 0.35 10.0 7.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1664 PF07889.12 ETS85146.1 - 0.11 12.5 20.4 0.071 13.1 1.7 4.2 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) KH_5 PF13184.6 ETS85146.1 - 2.5 8.3 4.9 20 5.4 0.5 3.6 3 1 0 3 3 3 0 NusA-like KH domain FlaC_arch PF05377.11 ETS85146.1 - 3 8.3 8.2 4.5 7.7 0.1 4.3 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) TcpS PF17456.2 ETS85146.1 - 5.6 7.0 9.3 5 7.2 1.2 2.9 2 1 0 2 2 2 0 Toxin-coregulated pilus protein S DUF932 PF06067.11 ETS85146.1 - 7.5 6.2 10.3 0.81 9.4 4.4 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF932) zf-C2H2 PF00096.26 ETS85147.1 - 3.5e-27 93.3 55.2 4.5e-05 23.7 2.2 8.5 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS85147.1 - 5.3e-19 67.3 54.0 0.0075 17.0 0.8 8.8 8 0 0 8 8 8 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ETS85147.1 - 2.5e-10 40.3 61.0 0.0011 19.3 1.1 8.6 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2_8 PF15909.5 ETS85147.1 - 2.8e-05 24.3 25.7 0.12 12.7 6.9 4.4 1 1 4 5 5 5 5 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 ETS85147.1 - 0.0014 18.3 28.7 1.6 8.6 0.1 6.4 6 0 0 6 6 6 3 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 ETS85147.1 - 0.0022 17.7 32.2 0.31 10.8 0.9 7.4 8 0 0 8 8 8 3 C2H2-type zinc-finger domain zf-met PF12874.7 ETS85147.1 - 0.0032 17.8 19.3 1.8 9.1 0.0 7.0 7 0 0 7 7 7 1 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 ETS85147.1 - 0.12 12.3 4.3 79 3.2 0.0 4.8 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) TRAF6_Z2 PF18048.1 ETS85147.1 - 0.68 10.1 0.0 0.68 10.1 0.0 3.3 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 DUF3958 PF13125.6 ETS85147.1 - 4 7.7 6.2 1.1 9.5 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) CHORD PF04968.12 ETS85147.1 - 4 8.2 36.5 9.7 7.0 0.9 6.4 2 2 5 7 7 7 0 CHORD RbpA PF13397.6 ETS85147.1 - 4.1 8.1 9.3 0.62 10.7 1.1 3.3 2 1 1 3 3 3 0 RNA polymerase-binding protein Ogr_Delta PF04606.12 ETS85147.1 - 5.3 7.1 17.4 0.5 10.4 2.5 4.3 3 1 2 5 5 5 0 Ogr/Delta-like zinc finger FOXP-CC PF16159.5 ETS85147.1 - 5.5 7.7 35.4 8 7.2 1.4 7.5 2 2 6 8 8 8 0 FOXP coiled-coil domain Cu-oxidase_2 PF07731.14 ETS85148.1 - 1.1e-41 141.8 5.9 1.1e-38 132.0 0.4 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ETS85148.1 - 5.7e-37 126.4 1.2 5.7e-37 126.4 1.2 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 ETS85148.1 - 5.4e-36 124.1 0.1 6.7e-34 117.3 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Terminase_4 PF05119.12 ETS85148.1 - 0.16 12.4 0.1 0.32 11.4 0.1 1.4 1 0 0 1 1 1 0 Phage terminase, small subunit CD225 PF04505.12 ETS85149.1 - 0.0087 16.2 0.5 0.0087 16.2 0.5 1.8 2 0 0 2 2 2 1 Interferon-induced transmembrane protein adh_short PF00106.25 ETS85150.1 - 7.3e-28 97.4 0.0 1.1e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS85150.1 - 2.9e-15 56.5 0.0 4e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS85150.1 - 0.0005 20.0 0.0 0.004 17.1 0.0 2.0 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 ETS85150.1 - 0.00054 20.2 0.1 0.007 16.6 0.1 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 ETS85150.1 - 0.0088 15.9 0.2 0.013 15.4 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS85150.1 - 0.12 11.8 0.1 0.93 8.9 0.1 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 ETS85150.1 - 0.13 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 ETS85150.1 - 0.14 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ABC_membrane PF00664.23 ETS85151.1 - 3.4e-41 141.7 5.9 4.7e-41 141.2 5.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ETS85151.1 - 7.5e-39 133.4 0.1 8.8e-30 104.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ETS85151.1 - 3e-10 39.9 0.3 0.0021 17.5 0.1 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETS85151.1 - 0.00021 21.2 0.2 0.048 13.5 0.0 2.5 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 ETS85151.1 - 0.00025 20.0 0.0 0.018 13.9 0.0 2.5 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 ETS85151.1 - 0.00046 20.5 0.9 0.01 16.1 0.3 2.9 2 1 0 2 2 2 1 AAA domain ABC_membrane_3 PF13748.6 ETS85151.1 - 0.00058 19.2 0.1 0.0012 18.2 0.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SbcCD_C PF13558.6 ETS85151.1 - 0.0012 19.0 0.2 0.53 10.6 0.2 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 ETS85151.1 - 0.0014 18.3 0.1 0.11 12.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 ETS85151.1 - 0.0024 17.5 0.1 0.18 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS85151.1 - 0.0055 17.1 0.6 0.044 14.2 0.2 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 ETS85151.1 - 0.029 14.6 0.0 0.074 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ETS85151.1 - 0.032 14.0 0.1 0.092 12.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 ETS85151.1 - 0.035 14.5 0.3 19 5.7 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 ETS85151.1 - 0.048 13.4 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 ETS85151.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ATP-synt_ab PF00006.25 ETS85151.1 - 0.089 12.4 0.1 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.22 ETS85151.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PEPCK_ATP PF01293.20 ETS85151.1 - 0.19 10.3 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase KGG PF10685.9 ETS85152.1 - 0.046 14.0 16.0 0.15 12.4 5.2 2.8 2 0 0 2 2 2 0 Stress-induced bacterial acidophilic repeat motif MFS_1 PF07690.16 ETS85153.1 - 1.7e-30 106.1 26.6 1.7e-30 106.1 26.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS85153.1 - 4.3e-12 45.6 4.9 4.3e-12 45.6 4.9 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Tyrosinase PF00264.20 ETS85154.1 - 1.2e-16 61.7 6.2 3.2e-16 60.3 6.2 1.8 1 1 0 1 1 1 1 Common central domain of tyrosinase MFS_1 PF07690.16 ETS85156.1 - 3.4e-45 154.5 48.7 2e-44 152.0 47.9 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS85156.1 - 1.5e-17 63.3 14.2 1.5e-17 63.3 14.2 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS85156.1 - 1.3e-09 37.5 11.9 1.3e-09 37.5 11.9 3.4 2 1 2 4 4 4 3 Sugar (and other) transporter DUF3632 PF12311.8 ETS85158.1 - 2.9e-25 89.7 0.1 6.9e-25 88.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) Invas_SpaK PF03519.14 ETS85158.1 - 0.022 14.8 0.1 0.054 13.6 0.1 1.7 1 1 0 1 1 1 0 Invasion protein B family DdrB PF12747.7 ETS85158.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 DdrB-like protein Prok-RING_4 PF14447.6 ETS85159.1 - 1.6e-08 34.3 11.7 1.6e-08 34.3 11.7 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ETS85159.1 - 7.2e-08 32.6 12.0 7.2e-08 32.6 12.0 2.7 3 1 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 ETS85159.1 - 4.4e-07 29.6 10.1 4.4e-07 29.6 10.1 2.9 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS85159.1 - 3.8e-06 26.7 9.5 3.8e-06 26.7 9.5 3.3 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ETS85159.1 - 5.4e-06 26.2 10.5 5.4e-06 26.2 10.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ETS85159.1 - 8.2e-06 26.0 9.1 8.2e-06 26.0 9.1 2.7 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ETS85159.1 - 1.4e-05 25.1 6.1 1.4e-05 25.1 6.1 2.8 2 1 1 3 3 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 ETS85159.1 - 3.5e-05 23.7 7.6 3.5e-05 23.7 7.6 2.7 3 1 0 3 3 3 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ETS85159.1 - 0.0089 16.1 5.8 0.027 14.5 5.8 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 ETS85159.1 - 0.051 13.7 10.0 0.69 10.1 10.2 2.7 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 ETS85159.1 - 2 8.2 12.2 0.051 13.4 3.7 2.6 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 ETS85159.1 - 6.4 7.0 8.5 0.68 10.1 3.3 2.1 3 0 0 3 3 2 0 Zinc-binding RING-finger Peptidase_A4 PF01828.17 ETS85160.1 - 2.7e-83 278.5 20.7 3.3e-83 278.3 20.7 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF588 PF04535.12 ETS85160.1 - 0.19 11.5 2.0 0.41 10.4 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF588) HHH_8 PF14716.6 ETS85161.1 - 0.015 15.6 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF3105 PF11303.8 ETS85162.1 - 0.013 15.6 0.1 0.071 13.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3105) LrgB PF04172.16 ETS85163.1 - 4e-57 193.2 11.8 4e-57 193.2 11.8 1.8 2 0 0 2 2 2 1 LrgB-like family ADP_ribosyl_GH PF03747.14 ETS85163.1 - 0.052 13.3 0.6 0.11 12.3 0.6 1.5 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase DUF2198 PF09964.9 ETS85163.1 - 3.9 7.6 8.0 5.2 7.2 3.7 3.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) BRCT PF00533.26 ETS85164.1 - 8.5e-17 61.3 0.0 2.1e-08 34.4 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ETS85164.1 - 0.0047 17.3 0.1 0.16 12.4 0.0 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Bep_C_terminal PF17841.1 ETS85164.1 - 0.071 13.3 0.1 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) PI3K_1B_p101 PF10486.9 ETS85164.1 - 0.094 10.5 2.4 0.13 10.1 2.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NOA36 PF06524.12 ETS85164.1 - 9.5 5.4 11.9 5.7 6.2 9.2 2.0 3 0 0 3 3 3 0 NOA36 protein NAD_binding_10 PF13460.6 ETS85165.1 - 3.9e-34 118.2 0.1 4.5e-34 117.9 0.1 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS85165.1 - 9.1e-09 35.1 0.0 1.2e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ETS85165.1 - 8.5e-08 32.0 0.2 1.7e-07 31.1 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 ETS85165.1 - 5.5e-05 22.5 1.0 0.028 13.6 0.2 2.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 ETS85165.1 - 0.006 15.7 0.0 0.0075 15.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.20 ETS85165.1 - 0.009 16.1 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 ETS85165.1 - 0.013 14.9 0.1 0.025 14.0 0.1 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DFP PF04127.15 ETS85165.1 - 0.079 12.8 0.5 1.6 8.5 0.1 2.1 1 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein ELFV_dehydrog PF00208.21 ETS85165.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Abhydrolase_1 PF00561.20 ETS85166.1 - 2.2e-09 37.3 0.2 3e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS85166.1 - 1.5e-08 35.5 0.0 3.6e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS85166.1 - 0.0013 18.1 0.1 0.026 13.8 0.1 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Beta-lactamase PF00144.24 ETS85167.1 - 2.5e-28 99.3 0.1 4.6e-28 98.4 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase HET PF06985.11 ETS85168.1 - 5.3e-12 46.3 0.0 5.2e-10 39.8 0.0 2.9 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) Lipoprotein_20 PF13942.6 ETS85168.1 - 0.04 13.8 0.7 0.078 12.9 0.7 1.4 1 0 0 1 1 1 0 YfhG lipoprotein Methyltransf_8 PF05148.15 ETS85168.1 - 0.049 13.5 0.1 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase Tannase PF07519.11 ETS85169.1 - 6e-81 272.7 0.6 7.4e-81 272.4 0.6 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 ETS85169.1 - 0.0032 17.0 0.2 0.21 11.0 0.2 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ETS85169.1 - 0.011 15.4 0.2 0.028 14.1 0.3 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS85169.1 - 0.014 14.7 0.0 0.042 13.1 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Complex1_LYR_2 PF13233.6 ETS85169.1 - 0.12 13.1 0.0 2.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Complex1_LYR-like Fungal_trans_2 PF11951.8 ETS85170.1 - 1.1e-05 24.5 0.0 3.4e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 ETS85171.1 - 7.7e-20 71.1 39.4 7.7e-20 71.1 39.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Tyrosinase PF00264.20 ETS85172.1 - 5.2e-42 144.6 0.9 8.8e-42 143.9 0.9 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Fungal_trans_2 PF11951.8 ETS85173.1 - 0.023 13.5 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain AATase PF07247.12 ETS85174.1 - 2e-08 33.3 0.0 1.7e-07 30.1 0.0 2.3 1 1 0 1 1 1 1 Alcohol acetyltransferase Peptidase_S9 PF00326.21 ETS85175.1 - 5e-44 150.3 0.1 8.1e-44 149.6 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 ETS85175.1 - 4e-11 42.9 0.0 3.4e-10 39.8 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 ETS85175.1 - 9e-09 35.6 0.0 2.9e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PD40 PF07676.12 ETS85175.1 - 5.2e-08 32.6 2.0 0.00011 22.1 0.1 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Peptidase_S15 PF02129.18 ETS85175.1 - 1.3e-07 31.5 0.9 0.02 14.5 2.0 2.5 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 ETS85175.1 - 2.9e-07 30.0 0.1 0.023 14.0 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS85175.1 - 2.7e-06 27.2 0.6 0.047 13.3 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 ETS85175.1 - 0.00011 21.9 0.0 0.00031 20.5 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 ETS85175.1 - 0.00049 20.0 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 ETS85175.1 - 0.001 18.7 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Abhydrolase_4 PF08386.10 ETS85175.1 - 0.0014 18.7 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein COesterase PF00135.28 ETS85175.1 - 0.0016 17.4 0.2 0.0022 17.0 0.2 1.1 1 0 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.12 ETS85175.1 - 0.0026 16.5 0.1 0.0069 15.1 0.1 1.8 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) PAE PF03283.13 ETS85175.1 - 0.03 13.4 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 Pectinacetylesterase ComK PF06338.11 ETS85175.1 - 0.048 13.3 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 ComK protein SprT-like PF10263.9 ETS85177.1 - 0.034 14.0 0.2 0.089 12.7 0.2 1.8 1 1 0 1 1 1 0 SprT-like family CHAT PF12770.7 ETS85180.1 - 1.2e-27 97.1 0.0 2.2e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 ETS85180.1 - 0.0032 17.7 0.7 0.015 15.6 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 ETS85180.1 - 0.041 14.1 0.1 0.13 12.5 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 ETS85180.1 - 0.047 13.6 0.2 0.19 11.6 0.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 ETS85180.1 - 0.049 13.5 0.3 0.11 12.4 0.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat HAD PF12710.7 ETS85181.1 - 0.057 13.8 0.0 0.17 12.3 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase p450 PF00067.22 ETS85182.1 - 8.4e-70 235.8 0.0 1.1e-69 235.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RFC1 PF08519.12 ETS85182.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain Tyrosinase PF00264.20 ETS85184.1 - 9.1e-35 120.9 6.0 3.1e-34 119.2 6.0 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase Kelch_1 PF01344.25 ETS85185.1 - 8.8e-30 102.0 10.1 8.2e-10 38.1 0.1 6.8 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 ETS85185.1 - 1.9e-28 97.8 11.6 2e-09 37.4 0.1 6.9 3 3 4 7 7 7 6 Kelch motif Kelch_4 PF13418.6 ETS85185.1 - 5.2e-25 87.2 9.1 3.3e-05 23.8 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 ETS85185.1 - 5.1e-22 77.7 18.2 9.4e-06 25.8 0.0 7.0 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 ETS85185.1 - 4.6e-13 48.8 3.7 0.14 12.1 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 ETS85185.1 - 7.2e-11 41.6 4.7 0.032 14.2 0.2 6.1 6 1 0 6 6 6 2 Kelch motif DUF1668 PF07893.13 ETS85185.1 - 0.037 13.4 0.1 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) DUF1381 PF07129.11 ETS85185.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1381) Cation_ATPase_C PF00689.21 ETS85186.1 - 2.6e-41 141.3 9.1 2.6e-41 141.3 9.1 3.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ETS85186.1 - 3.3e-40 137.5 0.4 3.3e-40 137.5 0.4 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 ETS85186.1 - 2.6e-19 70.4 0.0 3.7e-15 56.8 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ETS85186.1 - 4.8e-18 65.0 0.0 8.8e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ETS85186.1 - 2e-11 43.4 0.0 8.7e-11 41.4 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ETS85186.1 - 0.002 17.9 0.5 0.0039 17.0 0.5 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ETS85186.1 - 0.0089 16.4 0.0 0.32 11.4 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 ETS85187.1 - 1.7e-28 99.6 25.4 1.7e-28 99.6 25.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS85187.1 - 5.2e-11 42.1 23.0 1e-10 41.1 22.9 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MMPL PF03176.15 ETS85188.1 - 0.17 10.8 0.0 0.19 10.6 0.0 1.0 1 0 0 1 1 1 0 MMPL family PhyH PF05721.13 ETS85189.1 - 1.2e-07 32.2 0.0 2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 ETS85189.1 - 0.038 12.8 0.1 1.5 7.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1479) PepX_C PF08530.10 ETS85190.1 - 6.3e-37 127.7 0.0 8.5e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 ETS85190.1 - 1e-35 123.6 0.1 1.7e-33 116.4 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) F-box-like PF12937.7 ETS85191.1 - 0.0007 19.4 0.2 0.0015 18.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like Peptidase_S15 PF02129.18 ETS85192.1 - 2.5e-39 135.5 0.1 4.4e-39 134.7 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ETS85192.1 - 2.4e-38 132.3 0.1 3.6e-38 131.8 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 ETS85192.1 - 0.0045 16.3 0.0 0.0072 15.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Aldedh PF00171.22 ETS85193.1 - 2e-15 56.3 0.1 2.5e-09 36.2 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Peptidase_S15 PF02129.18 ETS85194.1 - 2.7e-46 158.3 0.1 3.5e-43 148.1 0.1 2.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ETS85194.1 - 9.9e-30 104.2 0.0 1.3e-29 103.8 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Cupin_2 PF07883.11 ETS85196.1 - 8.7e-07 28.6 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 ETS85196.1 - 0.052 13.2 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) LigB PF02900.18 ETS85198.1 - 2.8e-12 46.3 0.0 4e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase FAD_binding_3 PF01494.19 ETS85199.1 - 4.2e-19 69.0 0.0 5.7e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS85199.1 - 2.1e-07 30.5 0.0 4.1e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS85199.1 - 1.7e-06 28.1 0.6 6.3e-06 26.3 0.5 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS85199.1 - 7.7e-06 25.7 1.5 0.00046 19.9 2.1 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS85199.1 - 0.00025 20.2 1.9 0.00039 19.6 1.9 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 ETS85199.1 - 0.00028 19.9 0.7 0.023 13.6 0.3 2.2 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.22 ETS85199.1 - 0.003 16.7 0.4 0.0044 16.2 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 ETS85199.1 - 0.003 17.0 0.8 0.0047 16.3 0.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS85199.1 - 0.009 14.8 0.7 0.025 13.3 1.1 1.5 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 ETS85199.1 - 0.013 14.8 0.2 0.021 14.2 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 ETS85199.1 - 0.028 13.7 0.4 1.4 8.1 0.4 2.3 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 ETS85199.1 - 0.048 14.2 0.8 0.12 12.9 0.8 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1344 PF07076.11 ETS85199.1 - 0.081 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Rossmann-like PF10727.9 ETS85199.1 - 0.13 12.1 0.4 0.29 11.0 0.4 1.6 1 0 0 1 1 1 0 Rossmann-like domain Pyr_redox_3 PF13738.6 ETS85199.1 - 0.16 11.2 0.7 0.27 10.5 0.7 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 ETS85200.1 - 1.3e-61 208.8 0.0 1.7e-61 208.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cellulase PF00150.18 ETS85201.1 - 6.3e-18 65.2 0.9 1.3e-17 64.2 0.9 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-CCCH_4 PF18044.1 ETS85202.1 - 3e-09 36.4 3.5 6.5e-09 35.4 3.5 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ETS85202.1 - 1.8e-06 27.8 7.4 1.8e-06 27.8 7.4 1.7 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 ETS85202.1 - 1.1e-05 25.2 3.3 2.1e-05 24.3 3.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nucleoporin_FG PF13634.6 ETS85202.1 - 2.6e-05 25.0 136.7 0.13 13.1 35.1 7.3 3 1 3 6 6 6 2 Nucleoporin FG repeat region Torus PF16131.5 ETS85202.1 - 0.076 13.7 0.3 0.14 12.9 0.3 1.4 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 ETS85202.1 - 0.19 12.2 3.6 0.47 11.0 3.6 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Ribosomal_S10 PF00338.22 ETS85203.1 - 8e-27 93.3 0.4 9.6e-27 93.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.16 ETS85204.1 - 4.8e-09 35.8 0.4 8.7e-09 34.9 0.4 1.5 1 0 0 1 1 1 1 CUE domain NOA36 PF06524.12 ETS85204.1 - 0.39 10.0 4.3 0.65 9.3 4.3 1.2 1 0 0 1 1 1 0 NOA36 protein NmrA PF05368.13 ETS85206.1 - 2.9e-28 99.0 0.2 3.7e-28 98.7 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS85206.1 - 3.4e-17 62.9 0.3 4.7e-17 62.5 0.3 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ETS85206.1 - 3.1e-06 27.5 0.9 4.9e-06 26.8 0.2 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ETS85206.1 - 0.00049 19.6 0.1 0.0014 18.2 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ETS85206.1 - 0.00084 18.6 0.1 0.0013 18.0 0.1 1.3 1 0 0 1 1 1 1 Male sterility protein NAD_binding_2 PF03446.15 ETS85206.1 - 0.028 14.6 0.1 0.15 12.2 0.1 2.0 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Semialdhyde_dh PF01118.24 ETS85206.1 - 0.029 14.8 0.3 0.064 13.7 0.3 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ApbA PF02558.16 ETS85206.1 - 0.04 13.5 0.9 1.4 8.6 0.1 2.7 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.17 ETS85206.1 - 0.045 12.9 0.2 0.073 12.2 0.2 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DXP_reductoisom PF02670.16 ETS85206.1 - 0.39 11.4 4.1 31 5.3 0.1 3.1 2 1 0 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Fungal_trans PF04082.18 ETS85207.1 - 0.016 14.3 3.6 0.045 12.8 2.4 2.4 2 1 0 2 2 2 0 Fungal specific transcription factor domain ApbA PF02558.16 ETS85209.1 - 7.3e-30 103.6 0.2 1e-29 103.1 0.2 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 ETS85209.1 - 3.3e-28 98.4 0.0 8e-28 97.1 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal GFO_IDH_MocA PF01408.22 ETS85209.1 - 0.013 16.3 0.4 0.041 14.7 0.1 1.9 1 1 1 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ThiF PF00899.21 ETS85209.1 - 0.03 13.7 1.2 0.051 12.9 0.6 1.6 2 0 0 2 2 2 0 ThiF family PglD_N PF17836.1 ETS85209.1 - 0.048 14.3 0.0 0.13 13.0 0.0 1.7 1 0 0 1 1 1 0 PglD N-terminal domain NAD_binding_7 PF13241.6 ETS85209.1 - 0.052 14.0 0.0 0.084 13.3 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding IlvN PF07991.12 ETS85209.1 - 0.094 12.3 0.4 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Cutinase PF01083.22 ETS85210.1 - 2e-44 151.7 1.6 2.4e-44 151.4 1.6 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 ETS85210.1 - 0.0013 18.3 0.4 0.0018 17.8 0.4 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 ETS85210.1 - 0.0022 17.9 0.0 0.0031 17.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Lipase_3 PF01764.25 ETS85210.1 - 0.0039 17.1 0.0 0.0058 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 ETS85210.1 - 0.009 15.6 0.3 0.025 14.1 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 ETS85210.1 - 0.031 14.1 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase LacAB_rpiB PF02502.18 ETS85210.1 - 0.055 13.5 0.4 0.1 12.6 0.4 1.4 1 0 0 1 1 1 0 Ribose/Galactose Isomerase Oxidored_FMN PF00724.20 ETS85211.1 - 1.1e-90 304.4 0.0 1.3e-90 304.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 ETS85211.1 - 0.0044 16.5 0.1 4.2 6.8 0.0 2.9 2 1 1 3 3 3 2 Xylose isomerase-like TIM barrel RelB PF04221.12 ETS85211.1 - 0.05 13.6 0.2 0.12 12.3 0.1 1.6 2 0 0 2 2 2 0 RelB antitoxin DIM1 PF02966.16 ETS85211.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Mitosis protein DIM1 ABC2_membrane PF01061.24 ETS85212.1 - 3.3e-50 170.4 48.8 4.1e-26 91.7 15.9 3.3 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ETS85212.1 - 6.5e-34 117.4 0.4 4.6e-16 59.6 0.0 3.0 4 0 0 4 4 3 2 ABC transporter PDR_CDR PF06422.12 ETS85212.1 - 6.3e-27 93.3 4.6 1e-20 73.4 0.2 3.0 3 0 0 3 3 2 2 CDR ABC transporter RsgA_GTPase PF03193.16 ETS85212.1 - 3.3e-06 27.1 0.7 0.00018 21.4 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 ETS85212.1 - 3.7e-05 23.4 0.0 0.069 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ETS85212.1 - 0.00015 22.2 1.2 0.25 11.7 0.1 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA_18 PF13238.6 ETS85212.1 - 0.0013 19.2 0.3 0.4 11.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ETS85212.1 - 0.0014 18.3 0.4 0.05 13.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 ETS85212.1 - 0.002 18.3 0.1 0.092 12.9 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 ETS85212.1 - 0.0024 17.7 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 ETS85212.1 - 0.0059 17.0 0.3 3.9 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ETS85212.1 - 0.023 14.8 0.2 6.1 7.0 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 ETS85212.1 - 0.028 14.3 1.0 7 6.5 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 ETS85212.1 - 0.029 14.1 0.5 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ETS85212.1 - 0.029 14.6 0.8 3.6 7.8 0.2 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ETS85212.1 - 0.031 13.9 2.8 1.2 8.7 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 ETS85212.1 - 0.049 13.9 3.1 2.3 8.5 0.1 2.7 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 ETS85212.1 - 0.13 12.0 0.8 8.1 6.2 0.2 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_trans_N PF14510.6 ETS85212.1 - 0.22 12.2 2.4 0.5 11.0 0.0 2.7 3 0 0 3 3 2 0 ABC-transporter N-terminal NTPase_1 PF03266.15 ETS85212.1 - 0.66 9.9 1.7 14 5.6 0.3 2.9 3 0 0 3 3 3 0 NTPase Fungal_trans PF04082.18 ETS85213.1 - 1.4e-13 50.5 0.1 2e-13 50.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS85213.1 - 6.3e-09 35.8 7.6 1.5e-08 34.6 7.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Marek_SORF3 PF07153.11 ETS85213.1 - 0.081 12.3 0.2 0.19 11.0 0.2 1.6 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein Sulfotransfer_4 PF17784.1 ETS85214.1 - 4.2e-55 186.9 0.0 5e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ETS85214.1 - 2.4e-05 24.8 0.1 0.00076 19.9 0.0 2.5 2 1 1 3 3 3 1 Sulfotransferase family Amidohydro_2 PF04909.14 ETS85215.1 - 4.1e-41 141.7 0.0 5.4e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Dioxygenase_C PF00775.21 ETS85216.1 - 6.3e-06 25.7 0.0 0.00021 20.8 0.0 2.3 1 1 1 2 2 2 2 Dioxygenase BTB PF00651.31 ETS85218.1 - 2.4e-13 50.3 0.0 5.6e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ribonuc_L-PSP PF01042.21 ETS85219.1 - 1.3e-21 76.8 0.0 1.4e-21 76.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Isochorismatase PF00857.20 ETS85221.1 - 1.1e-22 81.1 0.3 6.4e-22 78.6 0.3 1.9 1 1 0 1 1 1 1 Isochorismatase family Tubulin PF00091.25 ETS85224.1 - 3.2e-60 203.7 0.0 6e-59 199.6 0.0 2.2 2 1 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ETS85224.1 - 1.6e-24 86.5 0.0 2.4e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 ETS85224.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Zw10 PF06248.13 ETS85224.1 - 0.052 12.1 0.1 0.078 11.5 0.1 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Tubulin_2 PF13809.6 ETS85224.1 - 0.076 12.2 0.2 2.2 7.4 0.0 2.7 3 0 0 3 3 3 0 Tubulin like Misat_Tub_SegII PF10644.9 ETS85224.1 - 0.12 12.7 0.0 0.48 10.7 0.0 1.9 2 0 0 2 2 2 0 Misato Segment II tubulin-like domain F-box-like PF12937.7 ETS85226.1 - 1.3e-06 28.2 0.0 3.4e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS85226.1 - 0.0056 16.5 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 ETS85226.1 - 2.3 8.8 4.1 18 5.9 0.1 4.1 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) MRJP PF03022.16 ETS85228.1 - 3.6e-28 98.8 0.0 8.9e-28 97.5 0.0 1.5 1 1 0 1 1 1 1 Major royal jelly protein SGL PF08450.12 ETS85228.1 - 0.00012 21.8 0.0 0.0021 17.7 0.0 2.6 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 ETS85228.1 - 0.012 15.6 0.2 6.3 6.9 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat NHL PF01436.21 ETS85228.1 - 0.027 14.5 1.2 32 4.8 0.0 4.1 4 0 0 4 4 4 0 NHL repeat Reg_prop PF07494.11 ETS85228.1 - 0.043 14.0 1.9 37 5.0 0.0 4.3 4 0 0 4 4 4 0 Two component regulator propeller PQQ_2 PF13360.6 ETS85228.1 - 0.09 12.3 0.2 1.1 8.8 0.2 2.3 1 1 0 1 1 1 0 PQQ-like domain Fungal_trans PF04082.18 ETS85230.1 - 1.2e-14 54.0 0.2 1.8e-14 53.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS85230.1 - 1.8e-08 34.4 14.0 4e-08 33.2 14.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ETS85231.1 - 3e-39 135.0 59.5 3e-39 135.0 59.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_43 PF04616.14 ETS85232.1 - 8.1e-28 97.5 2.5 1.3e-27 96.8 2.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Phage_head_chap PF11113.8 ETS85232.1 - 0.26 11.4 0.0 0.62 10.2 0.0 1.6 1 0 0 1 1 1 0 Head assembly gene product AA_permease PF00324.21 ETS85235.1 - 1.1e-127 426.5 29.9 1.4e-127 426.3 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS85235.1 - 1.6e-33 116.2 33.0 2e-33 115.9 33.0 1.0 1 0 0 1 1 1 1 Amino acid permease Asp PF00026.23 ETS85236.1 - 1.3e-57 195.6 3.7 1.9e-57 195.1 3.7 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS85236.1 - 3.4e-09 37.2 0.1 3.4e-09 37.2 0.1 2.8 2 2 1 3 3 3 1 Xylanase inhibitor N-terminal AIDA PF16168.5 ETS85236.1 - 9.7 6.4 8.5 20 5.3 2.9 2.7 2 1 0 2 2 2 0 Adhesin of bacterial autotransporter system, probable stalk Fungal_trans_2 PF11951.8 ETS85237.1 - 0.026 13.3 0.1 0.04 12.7 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain DNA_ligase_A_M PF01068.21 ETS85238.1 - 2.1e-50 171.2 0.2 7.3e-48 162.9 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ETS85238.1 - 2.3e-36 125.7 0.1 7.6e-36 124.0 0.0 2.0 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 ETS85238.1 - 1.2e-19 70.8 0.0 2.8e-12 47.1 0.0 3.3 2 1 1 3 3 3 2 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 ETS85238.1 - 0.0007 19.9 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 ETS85238.1 - 0.089 12.6 0.1 7 6.4 0.0 2.3 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain Aldose_epim PF01263.20 ETS85239.1 - 4.1e-59 200.3 0.0 5.2e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Lysozyme_like PF13702.6 ETS85240.1 - 0.02 14.6 0.6 0.2 11.3 0.6 2.1 1 1 0 1 1 1 0 Lysozyme-like DUF3767 PF12597.8 ETS85241.1 - 2e-35 120.6 0.2 3.2e-35 120.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) 5TM-5TMR_LYT PF07694.12 ETS85241.1 - 0.057 12.9 0.3 0.071 12.6 0.3 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT DUF1744 PF08490.12 ETS85242.1 - 2.2e-157 523.8 0.0 3.1e-157 523.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 ETS85242.1 - 2.2e-79 267.1 0.1 3.5e-79 266.4 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 ETS85242.1 - 3.4e-16 59.0 0.2 1.3e-13 50.5 0.1 3.0 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 ETS85242.1 - 6.5e-08 32.5 0.2 2.9e-07 30.4 0.2 2.0 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 ETS85242.1 - 6.3e-05 23.0 0.0 0.00025 21.1 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily Zf_RING PF16744.5 ETS85242.1 - 0.11 12.6 0.2 0.99 9.6 0.1 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger Methyltransf_2 PF00891.18 ETS85244.1 - 1.7e-24 86.3 0.0 2.4e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain DUF1996 PF09362.10 ETS85245.1 - 2.5e-81 273.1 0.4 3.1e-81 272.8 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Scytalone_dh PF02982.14 ETS85246.1 - 3.1e-15 56.3 1.2 3.5e-15 56.2 1.2 1.0 1 0 0 1 1 1 1 Scytalone dehydratase FAD_binding_3 PF01494.19 ETS85247.1 - 3.4e-19 69.3 0.1 1.2e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 ETS85247.1 - 0.00074 18.7 0.0 0.097 11.7 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.6 ETS85247.1 - 0.00075 19.7 0.0 0.0026 18.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS85247.1 - 0.0052 16.4 0.0 4.7 6.7 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS85247.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS85247.1 - 0.11 11.7 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS85247.1 - 0.13 11.3 0.3 2.9 6.9 0.2 2.3 2 1 0 2 2 2 0 Lycopene cyclase protein CVNH PF08881.10 ETS85248.1 - 8e-05 23.3 0.3 0.00012 22.8 0.3 1.3 1 0 0 1 1 1 1 CVNH domain Plasmod_Pvs28 PF06247.11 ETS85248.1 - 0.11 12.8 1.5 0.19 12.1 1.5 1.4 1 1 0 1 1 1 0 Pvs28 EGF domain adh_short PF00106.25 ETS85249.1 - 3.3e-44 150.7 0.3 4.4e-44 150.3 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS85249.1 - 5.1e-30 104.8 0.6 8.5e-30 104.0 0.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS85249.1 - 4.1e-15 56.2 0.2 5.9e-15 55.6 0.2 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS85249.1 - 0.0015 17.7 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 ETS85249.1 - 0.0043 16.4 0.0 0.03 13.6 0.0 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 ETS85249.1 - 0.007 16.3 0.9 0.013 15.4 0.9 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 ETS85249.1 - 0.0088 16.1 1.0 0.018 15.1 1.0 1.6 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain SBP_bac_11 PF13531.6 ETS85249.1 - 0.011 15.5 1.0 0.26 11.0 0.7 2.7 2 1 0 2 2 2 0 Bacterial extracellular solute-binding protein Epimerase PF01370.21 ETS85249.1 - 0.014 14.9 0.1 0.029 13.9 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS85249.1 - 0.025 13.6 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.10 ETS85249.1 - 0.084 12.2 0.0 0.18 11.2 0.0 1.5 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) TRI12 PF06609.13 ETS85250.1 - 4.9e-29 101.2 21.7 6.1e-29 100.9 21.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ETS85250.1 - 1.4e-20 73.6 57.0 1.8e-20 73.2 53.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4538 PF15061.6 ETS85250.1 - 5.5 6.8 14.8 8.6 6.2 0.1 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4538) Prefoldin PF02996.17 ETS85251.1 - 1.6e-35 121.6 0.3 6e-35 119.8 0.1 1.8 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 ETS85251.1 - 3e-05 23.9 0.4 0.0032 17.4 0.0 2.8 2 1 0 2 2 2 1 Prefoldin subunit FlaC_arch PF05377.11 ETS85251.1 - 0.00059 20.2 1.2 0.34 11.3 0.0 2.9 3 0 0 3 3 3 2 Flagella accessory protein C (FlaC) Filament PF00038.21 ETS85251.1 - 0.0046 16.6 1.4 0.34 10.4 0.1 2.1 2 0 0 2 2 2 2 Intermediate filament protein End3 PF12761.7 ETS85251.1 - 0.0055 16.9 0.7 0.17 12.0 0.1 2.3 2 0 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 DUF1664 PF07889.12 ETS85251.1 - 0.0082 16.2 0.3 2.2 8.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) THOC7 PF05615.13 ETS85251.1 - 0.012 15.8 0.3 0.37 11.1 0.1 2.2 2 0 0 2 2 2 0 Tho complex subunit 7 Laminin_II PF06009.12 ETS85251.1 - 0.039 14.0 0.1 0.85 9.6 0.0 2.1 2 0 0 2 2 2 0 Laminin Domain II DUF4201 PF13870.6 ETS85251.1 - 0.063 13.0 1.5 0.43 10.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) PspA_IM30 PF04012.12 ETS85251.1 - 0.12 11.9 2.9 5.9 6.4 0.2 2.1 2 0 0 2 2 2 0 PspA/IM30 family CLZ PF16526.5 ETS85251.1 - 0.12 12.7 4.1 4.2 7.8 0.1 2.8 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CC2-LZ PF16516.5 ETS85251.1 - 0.19 12.1 2.9 3.7 8.0 0.3 2.5 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator SlyX PF04102.12 ETS85251.1 - 0.6 10.8 3.8 6.8 7.4 0.3 2.9 3 0 0 3 3 3 0 SlyX CRAL_TRIO PF00650.20 ETS85252.1 - 8.8e-36 123.0 0.0 1.5e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ETS85252.1 - 8.4e-07 29.1 1.6 1.3e-06 28.5 0.1 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Mis14 PF08641.12 ETS85253.1 - 4.6e-15 56.1 3.0 2.8e-14 53.6 0.2 2.6 2 2 0 2 2 2 1 Kinetochore protein Mis14 like Pox_A_type_inc PF04508.12 ETS85253.1 - 0.68 9.9 4.6 24 5.0 0.1 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Glyco_hydro_7 PF00840.20 ETS85254.1 - 1.8e-183 610.2 12.1 2e-183 610.0 12.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CytadhesinP1 PF12378.8 ETS85254.1 - 0.073 13.2 0.0 0.29 11.3 0.0 2.0 2 0 0 2 2 2 0 Trypsin-sensitive surface-exposed protein DAO PF01266.24 ETS85255.1 - 2.1e-38 132.8 0.0 2.4e-38 132.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS85255.1 - 0.01 15.8 0.0 0.034 14.1 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ETS85255.1 - 0.014 15.6 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ETS85255.1 - 0.023 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ETS85255.1 - 0.17 11.1 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS85255.1 - 0.19 12.3 0.1 0.92 10.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_10 PF13673.7 ETS85256.1 - 1.9e-09 37.5 0.0 3.7e-09 36.6 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS85256.1 - 7.9e-09 35.8 0.0 1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS85256.1 - 4.6e-05 23.8 0.0 7.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS85256.1 - 0.018 15.0 0.2 0.046 13.7 0.2 1.8 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.6 ETS85256.1 - 0.02 14.6 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NAT PF04768.13 ETS85256.1 - 0.1 12.3 0.0 0.82 9.3 0.0 2.0 1 1 0 1 1 1 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase NmrA PF05368.13 ETS85257.1 - 2.8e-25 89.3 0.1 3.6e-25 88.9 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS85257.1 - 5.2e-13 49.3 0.0 7.4e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ETS85257.1 - 1.2e-09 38.5 0.3 3.5e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ETS85257.1 - 0.00037 20.0 0.0 0.00063 19.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 ETS85257.1 - 0.0023 18.0 0.1 0.0048 17.0 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 ETS85257.1 - 0.0026 17.8 0.1 0.0065 16.6 0.1 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 ETS85257.1 - 0.0041 16.3 0.1 0.017 14.3 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 ETS85257.1 - 0.009 16.4 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 ETS85257.1 - 0.027 15.2 0.0 0.053 14.2 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase SNF2_N PF00176.23 ETS85258.1 - 7.4e-06 24.9 0.0 1.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain PALP PF00291.25 ETS85259.1 - 4e-62 210.3 2.1 4.5e-62 210.1 2.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.16 ETS85260.1 - 6.9e-26 91.0 64.4 8.4e-23 80.8 36.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 ETS85262.1 - 5.1e-35 121.0 0.7 9.6e-35 120.1 0.7 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Planc_extracel PF07595.12 ETS85262.1 - 0.032 14.0 0.5 0.08 12.8 0.5 1.7 1 0 0 1 1 1 0 Planctomycete extracellular DUF2208 PF09973.9 ETS85263.1 - 0.012 15.3 0.2 0.023 14.3 0.1 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2208) p450 PF00067.22 ETS85264.1 - 5.5e-66 223.2 0.0 7e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 ETS85265.1 - 7e-20 71.3 42.1 1.8e-12 46.9 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS85265.1 - 1.3e-15 57.2 29.3 5.5e-15 55.2 29.3 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter Herpes_UL73 PF03554.13 ETS85265.1 - 1.2 9.2 12.3 2.2 8.3 3.1 3.7 3 0 0 3 3 3 0 UL73 viral envelope glycoprotein DIOX_N PF14226.6 ETS85266.1 - 1.3e-31 109.7 0.1 2.1e-31 109.1 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS85266.1 - 3e-23 82.2 0.0 9.4e-22 77.4 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily SUa-2TM PF18179.1 ETS85266.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain Ring_hydroxyl_A PF00848.19 ETS85267.1 - 2.3e-25 89.8 3.1 3.9e-12 46.6 0.1 2.3 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 ETS85267.1 - 1.1e-14 54.1 0.0 2.3e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FAD_binding_3 PF01494.19 ETS85268.1 - 4.6e-74 249.8 0.0 5.8e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 ETS85268.1 - 3.2e-25 89.1 0.0 6.4e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 ETS85268.1 - 1e-05 25.0 0.0 0.00084 18.7 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS85268.1 - 0.0002 21.8 0.0 0.0074 16.8 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS85268.1 - 0.00028 21.1 0.0 0.00094 19.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS85268.1 - 0.0004 20.1 0.0 0.064 12.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS85268.1 - 0.0014 17.4 0.0 0.0045 15.7 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 ETS85268.1 - 0.02 14.1 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 ETS85268.1 - 0.029 13.3 0.0 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase XdhC_C PF13478.6 ETS85268.1 - 0.063 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 ETS85268.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 ETS85268.1 - 0.13 11.6 0.1 0.23 10.7 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 ETS85268.1 - 0.13 11.5 0.0 0.55 9.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ETS85268.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Amidase PF01425.21 ETS85269.1 - 4.6e-102 342.3 0.0 5.6e-102 342.0 0.0 1.1 1 0 0 1 1 1 1 Amidase adh_short_C2 PF13561.6 ETS85270.1 - 2.3e-58 197.5 1.2 2.8e-58 197.3 1.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS85270.1 - 1.3e-40 139.0 1.3 1.6e-40 138.6 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS85270.1 - 1.2e-08 35.1 2.2 7.1e-08 32.6 1.5 2.1 1 1 1 2 2 2 1 KR domain Ysc84 PF04366.12 ETS85270.1 - 0.041 13.6 0.4 0.11 12.3 0.4 1.7 1 0 0 1 1 1 0 Las17-binding protein actin regulator Polysacc_deac_1 PF01522.21 ETS85271.1 - 5.1e-17 61.9 0.0 1e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ETS85271.1 - 1.5e-05 24.8 0.0 2.5e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Fungal_trans PF04082.18 ETS85272.1 - 3.6e-43 147.5 1.1 5.6e-43 146.9 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 ETS85272.1 - 8.9e-05 22.7 13.3 0.0018 18.6 2.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS85272.1 - 0.0047 17.6 11.6 0.083 13.8 1.6 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger FAD_binding_3 PF01494.19 ETS85273.1 - 2.1e-21 76.6 0.3 3.3e-20 72.7 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS85273.1 - 1.4e-07 31.1 0.1 0.0057 15.9 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ETS85273.1 - 4.4e-07 29.1 3.5 0.0003 19.8 0.1 2.1 1 1 1 2 2 2 2 Tryptophan halogenase DAO PF01266.24 ETS85273.1 - 2.7e-05 23.9 9.8 0.0065 16.1 0.0 2.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS85273.1 - 0.00012 22.2 1.2 0.00055 20.1 1.4 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ETS85273.1 - 0.00024 20.3 0.4 0.0005 19.2 0.4 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 ETS85273.1 - 0.0021 16.8 3.4 0.015 14.0 3.4 2.0 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 ETS85273.1 - 0.0025 17.0 7.6 0.038 13.1 6.9 2.2 2 0 0 2 2 2 1 FAD binding domain SE PF08491.10 ETS85273.1 - 0.0088 15.1 0.0 0.78 8.7 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase FAD_oxidored PF12831.7 ETS85273.1 - 0.011 15.1 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS85273.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS85273.1 - 0.14 12.1 1.0 0.55 10.2 1.0 2.0 1 1 0 1 1 1 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 ETS85273.1 - 0.15 11.3 4.5 5.2 6.2 1.4 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 ETS85273.1 - 0.18 11.0 2.0 3.5 6.8 1.0 2.2 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.18 ETS85273.1 - 0.24 11.3 1.2 0.43 10.4 1.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 ETS85273.1 - 0.27 11.8 4.4 1.6 9.3 3.4 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS85273.1 - 3.3 6.7 8.8 2.6 7.0 6.3 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Oxidored_FMN PF00724.20 ETS85274.1 - 2.2e-86 290.2 0.0 6.9e-86 288.6 0.0 1.6 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TPR_12 PF13424.6 ETS85275.1 - 2.3e-22 79.1 11.4 1.2e-11 44.7 0.2 4.8 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 ETS85275.1 - 1.9e-18 65.7 7.1 1.3e-05 24.9 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat HET PF06985.11 ETS85275.1 - 1e-09 38.9 8.4 2.3e-07 31.3 2.6 2.8 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.22 ETS85275.1 - 1.3e-07 31.1 0.0 1.1e-06 28.1 0.0 2.3 2 1 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 ETS85275.1 - 3.4e-07 30.8 0.0 1.4e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain TPR_1 PF00515.28 ETS85275.1 - 3.8e-07 29.6 1.1 0.23 11.4 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.6 ETS85275.1 - 1.4e-06 28.7 0.0 5e-05 23.6 0.0 2.8 1 1 1 2 2 2 1 AAA domain ATPase_2 PF01637.18 ETS85275.1 - 5.5e-06 26.5 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TPR_2 PF07719.17 ETS85275.1 - 8.3e-06 25.5 2.1 4.1 7.7 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 ETS85275.1 - 0.00061 19.8 0.6 13 6.3 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat NACHT PF05729.12 ETS85275.1 - 0.00099 19.1 0.0 0.0095 15.9 0.0 2.5 3 0 0 3 3 3 1 NACHT domain TPR_MalT PF17874.1 ETS85275.1 - 0.0013 18.2 0.6 0.0046 16.4 0.5 1.8 1 1 0 1 1 1 1 MalT-like TPR region TPR_7 PF13176.6 ETS85275.1 - 0.0037 17.2 0.8 8.6 6.7 0.1 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat IstB_IS21 PF01695.17 ETS85275.1 - 0.0045 16.7 0.0 0.013 15.2 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein ArsA_ATPase PF02374.15 ETS85275.1 - 0.01 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase ResIII PF04851.15 ETS85275.1 - 0.064 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 ETS85275.1 - 0.073 12.6 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ETS85275.1 - 0.088 13.2 0.0 6.2 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 ETS85275.1 - 0.11 12.5 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 ETS85275.1 - 0.12 12.1 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 ETS85275.1 - 0.13 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_5 PF07728.14 ETS85275.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TPR_16 PF13432.6 ETS85275.1 - 0.17 12.6 0.1 0.17 12.6 0.1 3.6 4 1 1 5 5 3 0 Tetratricopeptide repeat ParA PF10609.9 ETS85275.1 - 0.18 11.2 0.1 0.4 10.1 0.1 1.5 1 1 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase AAA PF00004.29 ETS85275.1 - 0.19 12.1 0.0 0.53 10.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_17 PF13431.6 ETS85275.1 - 0.42 11.1 4.6 6 7.5 0.0 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 ETS85275.1 - 0.58 10.9 4.8 29 5.6 0.1 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Flavin_Reduct PF01613.18 ETS85276.1 - 1.5e-13 51.1 0.0 2.1e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 ETS85276.1 - 2.6e-05 24.1 0.0 3.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF447) Ada_Zn_binding PF02805.16 ETS85277.1 - 1.2e-30 105.4 6.1 1.2e-30 105.4 6.1 1.5 2 0 0 2 2 2 1 Metal binding domain of Ada HTH_AraC PF00165.23 ETS85277.1 - 4.3e-05 23.5 0.1 7.5e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 ETS85277.1 - 0.00061 20.0 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DUF3884 PF13024.6 ETS85277.1 - 0.0012 18.3 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3884) Lactamase_B PF00753.27 ETS85278.1 - 6.4e-23 81.8 0.9 8.7e-23 81.4 0.9 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS85278.1 - 0.0017 17.9 0.2 0.0031 17.1 0.2 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CFEM PF05730.11 ETS85280.1 - 4.5e-07 29.9 6.7 4.5e-07 29.9 6.7 1.9 2 0 0 2 2 2 1 CFEM domain Abhydrolase_6 PF12697.7 ETS85281.1 - 2.8e-07 31.4 5.3 1.4e-06 29.1 5.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 ETS85281.1 - 1.9e-05 23.8 0.0 3.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase PAF-AH_p_II PF03403.13 ETS85281.1 - 7.3e-05 21.4 0.1 0.0096 14.5 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S9 PF00326.21 ETS85281.1 - 0.001 18.6 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 ETS85281.1 - 0.001 18.0 1.6 0.0053 15.7 0.6 2.3 2 1 0 2 2 2 1 Chlorophyllase enzyme Lipase_3 PF01764.25 ETS85281.1 - 0.0032 17.3 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.20 ETS85281.1 - 0.0054 16.4 0.1 0.0076 15.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 ETS85281.1 - 0.17 11.6 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein FSH1 PF03959.13 ETS85281.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF676 PF05057.14 ETS85281.1 - 0.19 11.2 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) HTH_36 PF13730.6 ETS85282.1 - 0.092 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Y_phosphatase PF00102.27 ETS85283.1 - 5.6e-55 186.5 0.1 1e-54 185.6 0.0 1.4 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 ETS85283.1 - 0.0026 17.6 0.0 0.0082 16.0 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 ETS85283.1 - 0.0047 16.9 0.0 0.0081 16.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 ETS85283.1 - 0.0077 16.4 0.0 0.034 14.3 0.0 2.2 1 1 0 1 1 1 1 Inositol hexakisphosphate NTP_transf_9 PF04248.12 ETS85284.1 - 8.7e-37 124.9 0.4 1.4e-27 95.4 0.2 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF427) Folliculin PF11704.8 ETS85285.1 - 1e-57 195.0 0.0 2.2e-57 193.9 0.0 1.6 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport AAA PF00004.29 ETS85286.1 - 2.2e-45 154.3 0.2 8.1e-45 152.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 ETS85286.1 - 1.1e-10 41.3 0.1 7.6e-10 38.6 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 ETS85286.1 - 7.8e-09 35.7 0.6 2.2e-08 34.2 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ETS85286.1 - 4.7e-08 33.3 0.0 1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 ETS85286.1 - 1.7e-07 31.8 0.4 3.7e-05 24.2 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 ETS85286.1 - 3.5e-06 26.4 0.0 6.6e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 ETS85286.1 - 4e-05 23.9 1.2 0.0088 16.3 0.1 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 ETS85286.1 - 0.00024 20.9 0.0 0.00069 19.4 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 ETS85286.1 - 0.00048 20.7 0.0 0.0015 19.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 ETS85286.1 - 0.00056 19.5 0.1 0.0026 17.3 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 ETS85286.1 - 0.0007 19.9 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 ETS85286.1 - 0.00081 19.1 0.0 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 ETS85286.1 - 0.0012 18.9 0.2 0.0055 16.7 0.0 2.1 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 ETS85286.1 - 0.0014 18.6 0.0 0.019 15.0 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 ETS85286.1 - 0.0015 17.8 0.0 0.003 16.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 ETS85286.1 - 0.0017 18.7 0.0 0.004 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 ETS85286.1 - 0.0032 17.4 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 NTPase NACHT PF05729.12 ETS85286.1 - 0.0037 17.2 0.2 0.11 12.4 0.0 3.0 4 0 0 4 4 4 1 NACHT domain AAA_3 PF07726.11 ETS85286.1 - 0.0054 16.6 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 ETS85286.1 - 0.0079 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 ETS85286.1 - 0.009 16.2 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ETS85286.1 - 0.0092 15.7 1.1 0.014 15.1 0.1 1.9 2 1 0 2 2 1 1 AAA domain TniB PF05621.11 ETS85286.1 - 0.01 15.3 0.0 0.5 9.8 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 ETS85286.1 - 0.011 15.5 0.1 0.031 14.0 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 ETS85286.1 - 0.021 14.6 0.2 0.056 13.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ETS85286.1 - 0.032 14.2 0.9 0.33 10.8 0.0 2.6 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 ETS85286.1 - 0.036 13.8 0.1 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 ETS85286.1 - 0.042 13.7 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase PF06745.13 ETS85286.1 - 0.045 13.1 1.1 0.56 9.5 0.0 2.4 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.26 ETS85286.1 - 0.076 12.7 0.2 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 ETS85286.1 - 0.078 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Zeta_toxin PF06414.12 ETS85286.1 - 0.084 12.1 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 ETS85286.1 - 0.09 12.3 1.3 0.27 10.8 0.1 2.2 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 ETS85286.1 - 0.12 12.7 0.1 0.37 11.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ETS85286.1 - 0.13 12.8 0.7 5.7 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ETS85286.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 ETS85286.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 ETS85286.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mpv17_PMP22 PF04117.12 ETS85288.1 - 2.8e-13 49.9 10.3 3.1e-13 49.8 9.2 1.7 1 1 0 1 1 1 1 Mpv17 / PMP22 family Autoind_synth PF00765.17 ETS85288.1 - 0.21 11.1 0.1 0.33 10.5 0.1 1.2 1 0 0 1 1 1 0 Autoinducer synthase Pyr_redox_2 PF07992.14 ETS85289.1 - 3.4e-08 33.1 0.1 6.7e-08 32.1 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS85289.1 - 6.2e-06 25.6 0.4 0.057 12.5 0.0 3.0 2 1 1 3 3 3 3 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ETS85289.1 - 1.8e-05 24.8 0.0 0.0024 17.8 0.0 2.5 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ETS85289.1 - 0.048 12.9 0.3 6.1 6.0 0.0 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lactamase_B_5 PF14597.6 ETS85289.1 - 0.086 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Peptidase_S10 PF00450.22 ETS85290.1 - 4.8e-71 240.3 0.0 6.1e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase COX14 PF14880.6 ETS85290.1 - 0.04 13.8 0.1 0.075 12.9 0.1 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly DUF1295 PF06966.12 ETS85292.1 - 3.7e-17 62.6 0.0 4.9e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 ETS85292.1 - 2.3e-06 26.6 4.0 9e-06 24.7 4.0 1.8 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 ETS85292.1 - 0.0014 18.6 0.0 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 ETS85292.1 - 0.019 15.4 0.0 0.036 14.5 0.0 1.5 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Rio2_N PF09202.11 ETS85292.1 - 0.22 11.8 0.0 0.44 10.8 0.0 1.4 1 0 0 1 1 1 0 Rio2, N-terminal peroxidase PF00141.23 ETS85293.1 - 1.5e-22 80.4 0.0 2.4e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Peroxidase MFS_1 PF07690.16 ETS85295.1 - 3.4e-41 141.3 45.9 4.4e-41 141.0 44.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS85295.1 - 5.9e-10 38.2 16.7 1.3e-09 37.0 16.6 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS85295.1 - 1.4e-05 24.1 14.9 1.4e-05 24.1 14.9 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter Mannitol_dh_C PF08125.13 ETS85297.1 - 2.8e-78 262.8 0.0 3.9e-78 262.3 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 ETS85297.1 - 7.4e-49 165.8 0.0 1.4e-48 164.9 0.0 1.5 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain p450 PF00067.22 ETS85298.1 - 1.7e-17 63.3 0.0 2.5e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HEAT_2 PF13646.6 ETS85301.1 - 2.4e-09 37.5 0.3 3.8e-06 27.2 0.0 3.9 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 ETS85301.1 - 0.00082 19.8 1.5 4 8.0 0.0 4.0 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.22 ETS85301.1 - 0.0018 18.4 0.3 0.38 11.1 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat Arm PF00514.23 ETS85301.1 - 0.014 15.4 0.8 0.69 10.0 0.0 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Lipase_3 PF01764.25 ETS85302.1 - 8.1e-31 106.8 0.0 1.2e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 ETS85302.1 - 3.8e-05 23.1 0.0 6.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS85302.1 - 0.00035 21.3 0.9 0.00051 20.7 0.7 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 ETS85302.1 - 0.0042 16.7 0.3 0.046 13.4 0.5 2.1 2 1 0 2 2 2 1 Putative esterase DUF2048 PF09752.9 ETS85302.1 - 0.0043 16.2 0.4 0.0076 15.4 0.4 1.3 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Thioesterase PF00975.20 ETS85302.1 - 0.0085 16.2 0.7 0.014 15.5 0.7 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF2974 PF11187.8 ETS85302.1 - 0.019 14.5 2.8 0.093 12.3 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 ETS85302.1 - 0.066 13.0 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS85302.1 - 0.075 12.7 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold FAD_binding_3 PF01494.19 ETS85303.1 - 1.1e-06 28.2 0.2 5.1e-06 26.0 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS85303.1 - 0.0011 18.3 0.0 0.0027 17.0 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS85303.1 - 0.0021 17.2 0.0 0.13 11.3 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein EspA PF03433.13 ETS85303.1 - 0.076 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 EspA-like secreted protein FAD_binding_3 PF01494.19 ETS85304.1 - 3.6e-20 72.5 0.3 1.2e-19 70.8 0.3 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS85304.1 - 7.2e-09 35.3 0.5 1.3e-06 27.9 0.3 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS85304.1 - 6.6e-07 29.5 0.7 1.7e-06 28.2 0.3 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS85304.1 - 1.1e-06 28.5 1.7 1.5e-06 28.0 1.7 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS85304.1 - 4.4e-06 26.0 1.9 8.5e-06 25.1 1.9 1.4 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 ETS85304.1 - 0.00031 19.7 0.2 0.021 13.7 0.2 2.9 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.14 ETS85304.1 - 0.00073 18.4 1.1 0.014 14.1 1.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 ETS85304.1 - 0.00094 19.7 0.2 0.0032 18.0 0.3 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ETS85304.1 - 0.0011 18.4 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ETS85304.1 - 0.0023 17.1 0.1 0.003 16.7 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.16 ETS85304.1 - 0.003 17.2 0.1 0.022 14.4 0.2 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 ETS85304.1 - 0.017 14.4 0.2 0.031 13.6 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ETS85304.1 - 0.025 13.8 0.2 0.042 13.1 0.2 1.3 1 0 0 1 1 1 0 Thi4 family DUF1344 PF07076.11 ETS85304.1 - 0.039 13.9 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Amino_oxidase PF01593.24 ETS85304.1 - 0.039 13.2 0.0 3.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 ETS85304.1 - 0.094 12.0 1.4 0.15 11.3 1.4 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS85304.1 - 0.11 12.5 0.4 2.3 8.2 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding MTS PF05175.14 ETS85304.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain p450 PF00067.22 ETS85305.1 - 2.4e-66 224.4 0.0 3.1e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 ETS85306.1 - 3.9e-21 75.9 0.2 2e-16 60.4 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS85306.1 - 1.3e-13 52.0 6.3 3.7e-13 50.6 6.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS85306.1 - 8.5e-08 31.7 0.0 2.7e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 EHN PF06441.12 ETS85306.1 - 0.15 12.5 1.1 0.43 11.0 0.1 2.3 3 0 0 3 3 3 0 Epoxide hydrolase N terminus DUF3530 PF12048.8 ETS85306.1 - 0.16 11.3 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) MFS_1 PF07690.16 ETS85307.1 - 2.8e-29 102.1 33.2 2.8e-29 102.1 33.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS85307.1 - 0.0011 18.0 1.7 0.0011 18.0 1.7 2.2 2 1 0 2 2 2 1 MFS_1 like family Methyltransf_23 PF13489.6 ETS85309.1 - 9.1e-21 74.4 0.0 1.8e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS85309.1 - 4.2e-11 43.4 0.0 8.4e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS85309.1 - 7e-08 32.4 0.0 2.5e-07 30.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS85309.1 - 1.5e-05 25.6 0.0 3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS85309.1 - 6.8e-05 23.5 0.0 0.00037 21.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ETS85309.1 - 0.0024 17.7 0.0 0.0063 16.3 0.0 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 ETS85309.1 - 0.0087 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 ETS85309.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 ETS85309.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Sun2_CC2 PF18580.1 ETS85309.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 GidB PF02527.15 ETS85309.1 - 0.13 11.5 0.0 0.53 9.6 0.0 1.9 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G MTS PF05175.14 ETS85309.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FAD_binding_3 PF01494.19 ETS85310.1 - 6.6e-12 45.3 0.0 2.9e-06 26.8 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 ETS85310.1 - 0.00064 19.9 0.1 0.0017 18.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS85310.1 - 0.0014 18.3 0.1 0.0029 17.3 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS85310.1 - 0.004 17.2 0.0 0.011 15.7 0.1 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ETS85310.1 - 0.034 13.4 0.0 0.73 9.0 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Esterase PF00756.20 ETS85311.1 - 6.5e-12 45.6 0.0 4.6e-11 42.9 0.0 1.9 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ETS85311.1 - 0.0023 17.5 0.0 0.0046 16.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ETS85311.1 - 0.044 13.0 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS85311.1 - 0.051 14.2 0.0 0.078 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.16 ETS85312.1 - 1.8e-14 53.5 31.5 4.5e-14 52.1 26.9 3.1 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 ETS85312.1 - 0.028 12.7 14.3 0.052 11.8 0.8 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF927 PF06048.11 ETS85312.1 - 0.2 11.2 2.5 0.58 9.7 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF927) BatA PF07584.11 ETS85312.1 - 0.31 11.4 4.2 0.38 11.2 0.1 2.8 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal Pam17 PF08566.10 ETS85312.1 - 0.41 10.5 1.9 0.43 10.4 0.1 2.0 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 Lactamase_B_3 PF13483.6 ETS85313.1 - 1.5e-07 31.5 0.0 2.3e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 ETS85313.1 - 8.1e-06 25.5 0.1 1.4e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ETS85313.1 - 0.00019 21.5 0.4 0.00029 20.9 0.4 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Fungal_trans PF04082.18 ETS85314.1 - 4.4e-10 39.0 2.9 7.6e-10 38.3 2.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Catalase PF00199.19 ETS85315.1 - 7.3e-172 571.7 0.6 1.1e-171 571.2 0.6 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 ETS85315.1 - 3.2e-16 59.3 0.0 6e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 ETS85315.1 - 4.6e-11 42.6 0.0 8.6e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 ETS85315.1 - 1.1e-05 25.4 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family Glyco_hydro_3_C PF01915.22 ETS85316.1 - 5.2e-44 150.7 0.0 1.1e-43 149.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ETS85316.1 - 1.8e-25 88.8 0.2 3.2e-25 88.0 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 ETS85316.1 - 4.4e-25 88.7 0.0 7.9e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Pectate_lyase_3 PF12708.7 ETS85317.1 - 1.2e-93 312.9 21.7 6.7e-84 281.0 4.7 3.1 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 ETS85317.1 - 1.4e-07 31.1 2.7 0.0015 18.2 0.3 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Egh16-like PF11327.8 ETS85318.1 - 7.7e-67 225.3 15.3 1.4e-65 221.2 15.3 2.0 1 1 0 1 1 1 1 Egh16-like virulence factor UDPGT PF00201.18 ETS85319.1 - 1e-10 41.0 0.1 1.5e-10 40.5 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ETS85319.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DUF1358 PF07096.11 ETS85320.1 - 0.18 11.8 1.3 1.4 8.9 1.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1358) CCDC92 PF14916.6 ETS85321.1 - 0.0011 18.6 0.1 0.0021 17.8 0.1 1.4 1 0 0 1 1 1 1 Coiled-coil domain of unknown function MFS_1 PF07690.16 ETS85322.1 - 1.1e-23 83.8 44.2 1.3e-23 83.5 44.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS85322.1 - 0.00072 18.5 8.8 0.00072 18.5 8.8 2.9 1 1 2 3 3 3 1 Sugar (and other) transporter Acetyltransf_7 PF13508.7 ETS85323.1 - 9.3e-08 32.4 0.0 1.3e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS85323.1 - 3e-07 30.7 0.0 3.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ETS85323.1 - 4.6e-06 26.5 0.0 8.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ETS85323.1 - 0.00015 22.5 0.0 0.00022 21.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS85323.1 - 0.00016 21.6 0.0 0.00036 20.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ETS85323.1 - 0.03 14.0 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ETS85323.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 ETS85323.1 - 0.22 11.0 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase HET PF06985.11 ETS85325.1 - 4e-21 75.9 0.0 7e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 ETS85327.1 - 7.8e-40 134.1 16.1 1.5e-05 25.6 0.1 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 ETS85327.1 - 1e-10 41.4 1.2 1e-10 41.4 1.2 2.0 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 ETS85327.1 - 6.3e-09 36.0 1.4 0.3 11.4 0.0 5.5 5 1 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 ETS85327.1 - 2.3e-07 30.5 1.7 2.3e-07 30.5 1.7 2.2 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 ETS85327.1 - 1.3e-06 27.4 9.3 0.12 11.0 0.0 5.6 3 1 3 6 6 6 3 Nucleoporin Nup120/160 F-box_4 PF15966.5 ETS85327.1 - 1.6e-05 24.8 0.5 5.8e-05 22.9 0.5 2.0 1 0 0 1 1 1 1 F-box WD40_like PF17005.5 ETS85327.1 - 0.00012 21.5 0.2 0.00023 20.6 0.2 1.4 1 0 0 1 1 1 1 WD40-like domain ChapFlgA PF13144.6 ETS85327.1 - 0.035 14.2 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 Chaperone for flagella basal body P-ring formation Acetyltransf_1 PF00583.25 ETS85328.1 - 7.3e-11 42.3 0.0 9.4e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS85328.1 - 0.0014 19.0 0.0 0.0022 18.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ETS85328.1 - 0.029 14.5 0.1 0.098 12.8 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 ETS85328.1 - 0.031 14.2 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mito_carr PF00153.27 ETS85329.1 - 1.6e-67 223.5 1.8 8.6e-22 76.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.20 ETS85330.1 - 6.4e-35 119.6 0.0 4.9e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Tannase PF07519.11 ETS85331.1 - 1.1e-97 327.9 0.1 1.4e-97 327.5 0.1 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Cyclase PF04199.13 ETS85332.1 - 1.5e-13 51.1 0.6 2.3e-13 50.5 0.6 1.3 1 0 0 1 1 1 1 Putative cyclase FMO-like PF00743.19 ETS85333.1 - 1.1e-07 30.7 0.0 2.3e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ETS85333.1 - 1.7e-06 27.5 0.0 0.0036 16.6 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS85333.1 - 5.4e-06 25.9 0.3 0.00051 19.4 0.3 3.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS85333.1 - 1.1e-05 24.8 0.0 0.0002 20.6 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ETS85333.1 - 2.3e-05 24.5 0.6 9.3e-05 22.6 0.1 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 ETS85333.1 - 0.0011 18.4 0.1 0.003 16.9 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 ETS85333.1 - 0.0016 18.1 2.0 1.8 8.0 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase Shikimate_DH PF01488.20 ETS85333.1 - 0.0087 16.1 0.0 0.18 11.9 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 ETS85333.1 - 0.024 14.7 0.6 2.8 7.9 0.2 3.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 ETS85333.1 - 0.17 12.3 0.2 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding OmdA PF13376.6 ETS85334.1 - 4.5e-10 39.4 0.5 1.3e-09 37.9 0.1 2.1 2 0 0 2 2 2 1 Bacteriocin-protection, YdeI or OmpD-Associated HTH_23 PF13384.6 ETS85334.1 - 0.01 15.6 0.1 0.027 14.3 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.6 ETS85334.1 - 0.038 13.8 0.5 0.086 12.6 0.5 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Trp_repressor PF01371.19 ETS85334.1 - 0.079 13.1 0.4 0.23 11.6 0.2 1.8 2 0 0 2 2 2 0 Trp repressor protein Cu_amine_oxid PF01179.20 ETS85335.1 - 3.4e-162 540.0 0.0 4.1e-162 539.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 ETS85335.1 - 6.4e-09 35.9 0.0 1.8e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 ETS85335.1 - 3.9e-07 30.4 0.0 9.9e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain RVT_connect PF06815.13 ETS85335.1 - 0.055 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase connection domain Apolipo_F PF15148.6 ETS85336.1 - 0.0081 15.7 0.1 0.0095 15.4 0.1 1.1 1 0 0 1 1 1 1 Apolipoprotein F MFS_1 PF07690.16 ETS85338.1 - 6.6e-23 81.2 20.2 8.4e-23 80.9 20.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2104 PF09877.9 ETS85338.1 - 0.15 12.3 1.2 0.79 10.0 0.1 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) TauD PF02668.16 ETS85339.1 - 1.9e-49 168.9 0.0 2.5e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_3 PF01494.19 ETS85340.1 - 2.1e-16 60.2 0.1 2.9e-11 43.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS85340.1 - 4.9e-06 26.7 1.4 1.2e-05 25.5 1.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS85340.1 - 0.00013 21.7 3.4 0.00029 20.5 2.7 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS85340.1 - 0.00021 20.5 2.2 0.00038 19.6 2.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS85340.1 - 0.00042 19.7 2.3 0.001 18.4 0.8 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS85340.1 - 0.0036 16.4 1.3 0.0058 15.8 1.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ETS85340.1 - 0.0041 16.4 0.8 0.0081 15.5 0.8 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ETS85340.1 - 0.0054 15.5 0.8 0.0099 14.6 0.8 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 ETS85340.1 - 0.011 16.2 0.6 0.028 15.0 0.6 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ETS85340.1 - 0.017 14.5 2.1 0.028 13.8 2.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ETS85340.1 - 0.039 13.2 2.4 0.13 11.5 0.2 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Rossmann-like PF10727.9 ETS85340.1 - 0.058 13.3 1.2 0.12 12.2 0.7 1.8 2 0 0 2 2 2 0 Rossmann-like domain Trp_halogenase PF04820.14 ETS85340.1 - 0.089 11.6 0.2 0.5 9.2 0.3 1.9 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 ETS85340.1 - 0.097 12.3 0.2 0.19 11.4 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Disulph_isomer PF06491.11 ETS85340.1 - 0.17 11.9 0.0 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Disulphide isomerase 3HCDH_N PF02737.18 ETS85340.1 - 0.26 11.2 0.8 0.42 10.5 0.8 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DBR1 PF05011.13 ETS85341.1 - 3.9e-44 150.5 0.0 6.7e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 ETS85341.1 - 4.2e-07 30.7 0.6 6.3e-07 30.1 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GRP PF07172.11 ETS85341.1 - 0.43 11.3 19.3 0.79 10.4 19.3 1.5 1 0 0 1 1 1 0 Glycine rich protein family TPR_12 PF13424.6 ETS85342.1 - 1.7e-88 291.0 37.3 2.1e-18 66.3 1.3 7.5 2 1 5 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.6 ETS85342.1 - 7.8e-74 241.8 15.4 1.4e-13 50.2 0.3 8.8 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_2 PF07719.17 ETS85342.1 - 2.3e-12 46.0 6.7 0.084 13.0 0.1 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 ETS85342.1 - 3.7e-12 45.5 2.4 0.0086 15.9 0.1 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 ETS85342.1 - 8.5e-12 44.2 11.1 0.058 13.4 0.1 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS85342.1 - 4e-11 42.9 15.8 4.7e-08 32.8 4.6 3.7 1 1 3 4 4 4 2 MalT-like TPR region TPR_4 PF07721.14 ETS85342.1 - 3e-09 36.6 13.6 0.03 14.9 0.1 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 ETS85342.1 - 8.1e-09 36.0 8.6 0.014 16.1 0.9 6.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 ETS85342.1 - 1e-07 31.6 5.1 0.03 14.5 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 ETS85342.1 - 2.2e-06 27.6 1.7 2.2 8.8 0.0 6.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS85342.1 - 3.2e-06 27.6 13.5 0.0091 16.5 0.4 5.2 3 1 4 7 7 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS85342.1 - 1.3e-05 25.3 1.3 0.94 9.7 0.1 4.9 2 1 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 ETS85342.1 - 3.6e-05 24.2 11.7 1.9 9.5 0.2 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat NB-ARC PF00931.22 ETS85342.1 - 3.7e-05 23.0 0.0 7.9e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Abhydrolase_6 PF12697.7 ETS85342.1 - 0.0011 19.6 0.0 0.0032 18.1 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS85342.1 - 0.0017 17.7 0.0 0.0037 16.5 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AAA_22 PF13401.6 ETS85342.1 - 0.091 13.0 0.0 0.89 9.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain DUF4404 PF14357.6 ETS85342.1 - 0.15 12.7 9.1 4.6 8.0 0.4 5.3 4 2 2 6 6 6 0 Domain of unknown function (DUF4404) PPR PF01535.20 ETS85342.1 - 0.17 12.2 0.1 1.2e+02 3.3 0.0 4.0 4 0 0 4 4 3 0 PPR repeat HET PF06985.11 ETS85344.1 - 8.9e-38 129.9 0.1 1.9e-37 128.8 0.0 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.7 ETS85345.1 - 1.6e-09 37.5 2.2 1.7e-09 37.4 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ETS85345.1 - 2.8e-08 33.4 1.3 5.6e-08 32.5 0.4 2.0 2 0 0 2 2 2 1 F-box domain F-box_5 PF18511.1 ETS85345.1 - 0.014 15.0 0.1 0.037 13.6 0.1 1.7 1 0 0 1 1 1 0 F-box ANAPC5 PF12862.7 ETS85345.1 - 0.059 13.4 0.1 0.65 10.1 0.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 LRR_6 PF13516.6 ETS85345.1 - 0.73 10.0 2.1 3.7 7.8 0.3 3.2 4 0 0 4 4 4 0 Leucine Rich repeat Skp1_POZ PF03931.15 ETS85346.1 - 2.7e-10 40.3 0.0 4.7e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Ras PF00071.22 ETS85347.1 - 9.2e-48 161.9 0.0 1.2e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS85347.1 - 3.3e-20 72.5 0.0 7.2e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS85347.1 - 1.2e-05 24.8 0.0 3.2e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 ETS85347.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Asp PF00026.23 ETS85348.1 - 5.1e-68 229.8 16.0 4.7e-46 157.7 12.5 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS85348.1 - 3.9e-10 40.2 11.1 1.6e-08 35.0 2.9 3.6 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Sugar_tr PF00083.24 ETS85349.1 - 4e-95 319.3 23.5 4.6e-95 319.1 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS85349.1 - 8.7e-11 41.3 41.7 2.5e-09 36.5 40.3 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Ras PF00071.22 ETS85350.1 - 4.5e-13 49.1 0.0 5.3e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS85350.1 - 0.02 15.1 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 ETS85351.1 - 0.093 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fungal_trans PF04082.18 ETS85352.1 - 1.5e-05 24.1 0.0 2.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain eIF3m_C_helix PF18005.1 ETS85352.1 - 0.042 13.5 0.2 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix Fungal_trans PF04082.18 ETS85353.1 - 0.0023 17.0 0.1 0.003 16.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 ETS85353.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain DAO PF01266.24 ETS85354.1 - 4.8e-14 52.7 0.3 1.7e-08 34.4 0.1 2.8 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS85354.1 - 0.0029 16.7 0.0 1.3 8.0 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain Thi4 PF01946.17 ETS85354.1 - 0.016 14.5 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 ETS85354.1 - 0.019 14.2 0.0 0.93 8.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS85354.1 - 0.021 15.1 0.1 0.06 13.6 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 ETS85354.1 - 0.048 13.7 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 ETS85354.1 - 0.065 12.3 0.1 0.097 11.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.16 ETS85355.1 - 3e-26 92.2 24.5 3e-26 92.2 24.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4131 PF13567.6 ETS85355.1 - 0.014 15.1 0.2 0.014 15.1 0.2 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) OATP PF03137.20 ETS85355.1 - 5 5.3 18.8 0.82 7.9 1.0 3.3 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF805 PF05656.14 ETS85356.1 - 0.016 15.6 3.8 0.016 15.6 3.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF805) Phage_holin_2_2 PF10746.9 ETS85356.1 - 0.07 12.8 1.4 0.14 11.9 0.7 1.8 1 1 0 1 1 1 0 Phage holin T7 family, holin superfamily II p450 PF00067.22 ETS85357.1 - 1.2e-45 156.1 0.0 1.6e-45 155.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NACHT PF05729.12 ETS85358.1 - 0.0056 16.6 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Glyco_hydro_18 PF00704.28 ETS85359.1 - 7.2e-11 42.4 0.0 1.1e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Metallophos PF00149.28 ETS85361.1 - 2.4e-33 116.4 0.0 1.1e-28 101.2 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 ETS85361.1 - 0.0082 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Smg4_UPF3 PF03467.15 ETS85362.1 - 4.2e-31 108.3 0.1 4.2e-31 108.3 0.1 4.3 4 1 0 4 4 4 1 Smg-4/UPF3 family RRM_1 PF00076.22 ETS85362.1 - 4.9e-07 29.5 0.3 8.7e-05 22.3 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GLEYA PF10528.9 ETS85363.1 - 6.2e-15 55.4 0.5 1.1e-14 54.6 0.5 1.4 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 ETS85363.1 - 0.0073 16.1 1.2 0.019 14.8 0.1 2.0 2 0 0 2 2 2 1 PA14 domain Glyco_hydro_3_C PF01915.22 ETS85364.1 - 2.1e-42 145.4 0.0 6.8e-42 143.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ETS85364.1 - 8.6e-24 83.5 0.1 1.8e-23 82.5 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 ETS85364.1 - 1.3e-20 74.1 0.0 2.5e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain p450 PF00067.22 ETS85365.1 - 2.8e-42 145.0 0.0 1.4e-37 129.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Nramp PF01566.18 ETS85365.1 - 0.15 11.0 0.0 0.29 10.0 0.0 1.4 1 0 0 1 1 1 0 Natural resistance-associated macrophage protein MFS_1 PF07690.16 ETS85366.1 - 5.9e-34 117.5 25.5 9.1e-33 113.6 27.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DAO PF01266.24 ETS85367.1 - 8.8e-43 147.2 0.1 1e-42 147.0 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS85367.1 - 4.3e-05 23.7 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS85367.1 - 5.9e-05 23.1 0.0 0.025 14.6 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 ETS85367.1 - 7.9e-05 22.0 0.0 0.00019 20.7 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 ETS85367.1 - 0.00027 20.3 0.0 0.061 12.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS85367.1 - 0.0064 15.6 0.0 0.15 11.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS85367.1 - 0.024 13.9 0.1 0.079 12.2 0.1 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ETS85367.1 - 0.086 12.1 0.0 0.29 10.4 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Hydrolase PF00702.26 ETS85368.1 - 3.7e-08 33.9 0.0 1.2e-07 32.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ETS85368.1 - 7.1e-06 26.2 0.0 8.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Epimerase PF01370.21 ETS85369.1 - 2.4e-20 73.1 0.0 3.2e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS85369.1 - 5.5e-12 45.3 0.0 7.5e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ETS85369.1 - 2.5e-10 40.3 0.0 4.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ETS85369.1 - 6.6e-09 35.3 0.0 0.0026 17.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 ETS85369.1 - 1.9e-07 31.1 0.0 5.4e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 ETS85369.1 - 1.2e-05 25.3 0.0 1.9e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS85369.1 - 9.1e-05 21.7 0.0 0.00013 21.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 ETS85369.1 - 0.0013 18.3 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 ETS85369.1 - 0.007 16.0 0.0 0.02 14.4 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Glyco_hydr_30_2 PF14587.6 ETS85370.1 - 2.8e-13 50.2 2.7 1.4e-11 44.6 0.5 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 ETS85370.1 - 7e-13 48.5 0.3 1.1e-12 47.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 ETS85370.1 - 0.00042 20.5 1.5 0.0013 18.9 1.5 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 ETS85370.1 - 0.00087 18.4 0.2 0.0014 17.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain DUF4596 PF15363.6 ETS85370.1 - 8.1 6.8 6.2 81 3.6 0.2 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4596) F-box-like PF12937.7 ETS85372.1 - 4.8e-09 36.0 0.4 1.1e-08 34.8 0.4 1.7 1 0 0 1 1 1 1 F-box-like DUF5381 PF17353.2 ETS85373.1 - 0.38 10.5 2.2 0.79 9.5 2.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5381) Hol_Tox PF16935.5 ETS85374.1 - 0.22 11.6 0.1 0.4 10.7 0.1 1.4 1 0 0 1 1 1 0 Putative Holin-like Toxin (Hol-Tox) zf-TRM13_CCCH PF11722.8 ETS85374.1 - 3.5 7.5 0.0 3.5 7.5 0.0 4.6 5 1 0 5 5 5 0 CCCH zinc finger in TRM13 protein TRF PF08558.10 ETS85376.1 - 5.3e-45 153.9 0.3 9.5e-45 153.1 0.3 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 ETS85376.1 - 9.1e-05 22.6 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain AAA_11 PF13086.6 ETS85377.1 - 8.8e-08 32.3 0.0 0.00057 19.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 ETS85377.1 - 0.00019 21.2 0.0 0.22 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 ETS85377.1 - 0.043 14.2 0.0 0.96 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 ETS85377.1 - 0.051 13.3 0.0 2 8.1 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Aldedh PF00171.22 ETS85378.1 - 1.5e-186 620.4 0.4 1.7e-186 620.2 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family COesterase PF00135.28 ETS85379.1 - 6.4e-89 299.1 0.0 8e-89 298.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS85379.1 - 7.1e-07 29.3 0.1 6.6e-06 26.1 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS85379.1 - 0.073 12.5 0.2 0.13 11.7 0.2 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family AAA_12 PF13087.6 ETS85380.1 - 2.6e-16 59.8 0.0 4.8e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ETS85380.1 - 5.4e-08 32.9 0.0 9.9e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ETS85380.1 - 0.056 13.2 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Caskin-tail PF16632.5 ETS85380.1 - 0.14 12.6 0.5 0.31 11.5 0.5 1.5 1 0 0 1 1 1 0 C-terminal region of Caskin KASH_CCD PF14662.6 ETS85381.1 - 5.4e-09 36.2 15.3 7.3e-09 35.7 15.3 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH HALZ PF02183.18 ETS85381.1 - 4e-06 26.9 8.4 0.024 14.8 0.5 4.2 4 0 0 4 4 3 2 Homeobox associated leucine zipper ADIP PF11559.8 ETS85381.1 - 8.7e-05 22.7 18.0 0.02 15.0 5.6 2.2 1 1 0 2 2 2 2 Afadin- and alpha -actinin-Binding Sec2p PF06428.11 ETS85381.1 - 0.00016 21.6 3.2 0.00016 21.6 3.2 2.5 1 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF3450 PF11932.8 ETS85381.1 - 0.00068 19.0 11.0 0.0011 18.3 7.8 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) Golgin_A5 PF09787.9 ETS85381.1 - 0.0037 16.8 9.7 0.0037 16.8 9.7 1.9 1 1 1 2 2 2 1 Golgin subfamily A member 5 Phage_HK97_TLTM PF06120.11 ETS85381.1 - 0.0063 15.7 5.9 0.25 10.5 1.5 2.3 1 1 1 2 2 2 2 Tail length tape measure protein YabA PF06156.13 ETS85381.1 - 0.0089 16.6 13.5 0.1 13.3 2.7 3.4 1 1 2 3 3 3 2 Initiation control protein YabA Cnn_1N PF07989.11 ETS85381.1 - 0.014 15.5 17.0 0.018 15.2 2.3 3.8 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 TACC_C PF05010.14 ETS85381.1 - 0.022 14.5 12.9 0.077 12.8 4.4 2.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HemX PF04375.14 ETS85381.1 - 0.022 14.0 1.2 0.022 14.0 1.2 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF3584 PF12128.8 ETS85381.1 - 0.029 11.9 16.0 0.096 10.2 16.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Tropomyosin PF00261.20 ETS85381.1 - 0.033 13.6 17.7 0.045 13.1 17.7 1.1 1 0 0 1 1 1 0 Tropomyosin Spc7 PF08317.11 ETS85381.1 - 0.036 12.9 16.8 0.0078 15.1 7.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Taxilin PF09728.9 ETS85381.1 - 0.044 13.0 16.9 0.21 10.7 3.9 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein APG6_N PF17675.1 ETS85381.1 - 0.081 13.4 18.4 0.32 11.5 3.6 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Csm1_N PF18504.1 ETS85381.1 - 0.13 12.6 0.5 0.13 12.6 0.5 3.5 2 1 1 3 3 3 0 Csm1 N-terminal domain ZapB PF06005.12 ETS85381.1 - 0.14 12.6 17.3 6.3e+02 0.9 17.3 3.6 1 1 0 1 1 1 0 Cell division protein ZapB DUF148 PF02520.17 ETS85381.1 - 0.17 12.0 8.5 1.9 8.6 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function DUF148 Bacillus_HBL PF05791.11 ETS85381.1 - 0.23 11.3 4.5 1.2 9.0 0.7 2.3 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) HAP1_N PF04849.13 ETS85381.1 - 0.24 10.5 15.2 0.82 8.8 5.5 2.3 1 1 0 1 1 1 0 HAP1 N-terminal conserved region BRE1 PF08647.11 ETS85381.1 - 0.26 11.4 16.6 0.3 11.2 7.0 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase CC2-LZ PF16516.5 ETS85381.1 - 0.29 11.5 15.1 1.1 9.6 0.5 3.7 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator HMMR_N PF15905.5 ETS85381.1 - 0.38 10.2 15.4 0.07 12.6 9.6 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Lebercilin PF15619.6 ETS85381.1 - 0.42 10.2 19.2 0.37 10.4 17.1 1.8 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CENP-F_leu_zip PF10473.9 ETS85381.1 - 0.46 10.5 16.1 6.9 6.7 4.1 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Med9 PF07544.13 ETS85381.1 - 0.52 10.4 8.3 1.3 9.1 0.0 3.6 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Jnk-SapK_ap_N PF09744.9 ETS85381.1 - 0.6 10.3 19.6 1.3 9.2 10.6 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 BST2 PF16716.5 ETS85381.1 - 0.9 10.2 10.0 14 6.3 3.4 3.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 PikAIV_N PF18605.1 ETS85381.1 - 0.94 9.1 7.5 6.5 6.4 0.1 3.3 2 1 1 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF812 PF05667.11 ETS85381.1 - 0.95 8.3 16.1 2.8 6.7 16.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Fib_alpha PF08702.10 ETS85381.1 - 1.2 9.3 8.3 0.59 10.3 2.0 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 ETS85381.1 - 1.2 9.4 10.3 9.6 6.6 1.5 2.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NRBF2 PF08961.10 ETS85381.1 - 1.3 8.6 15.6 1.8 8.1 2.2 3.0 1 1 2 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator TMF_TATA_bd PF12325.8 ETS85381.1 - 1.4 9.2 15.0 1.1 9.5 1.4 2.2 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.21 ETS85381.1 - 1.6 8.9 18.2 1.3 9.1 3.3 4.1 1 1 3 4 4 4 0 bZIP transcription factor CENP-H PF05837.12 ETS85381.1 - 1.9 8.9 14.5 3.9 7.9 7.0 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF4140 PF13600.6 ETS85381.1 - 1.9 9.0 11.4 33 5.0 0.9 3.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FapA PF03961.13 ETS85381.1 - 2 6.9 12.0 0.77 8.3 4.2 2.0 1 1 0 2 2 2 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 ETS85381.1 - 2.5 7.6 12.6 63 3.0 12.5 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit SlyX PF04102.12 ETS85381.1 - 2.9 8.6 9.4 2 9.1 0.2 3.6 1 1 3 4 4 4 0 SlyX TSC22 PF01166.18 ETS85381.1 - 3 8.2 12.3 4.9 7.5 0.1 4.1 1 1 4 5 5 5 0 TSC-22/dip/bun family JIP_LZII PF16471.5 ETS85381.1 - 3.1 8.1 12.0 12 6.2 0.1 3.6 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II DASH_Spc34 PF08657.10 ETS85381.1 - 3.3 7.4 11.2 0.23 11.2 1.8 2.3 1 1 1 2 2 2 0 DASH complex subunit Spc34 Cep57_CLD_2 PF14197.6 ETS85381.1 - 3.4 7.8 19.6 6.8 6.9 4.4 3.4 2 1 2 4 4 4 0 Centrosome localisation domain of PPC89 Troponin PF00992.20 ETS85381.1 - 4 7.7 19.4 0.09 13.1 8.4 2.3 1 1 1 2 2 2 0 Troponin PRKG1_interact PF15898.5 ETS85381.1 - 4.1 8.4 20.4 6.2 7.8 5.4 3.8 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain DUF4200 PF13863.6 ETS85381.1 - 5.2 7.5 18.5 0.36 11.2 10.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DivIC PF04977.15 ETS85381.1 - 5.3 6.9 19.9 2.2 8.1 2.8 4.2 1 1 3 4 4 4 0 Septum formation initiator Phage_GPO PF05929.11 ETS85381.1 - 5.5 6.5 8.3 0.76 9.3 1.5 2.0 1 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase GPS2_interact PF15784.5 ETS85381.1 - 5.8 7.4 10.3 0.38 11.2 2.3 2.6 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain SPATA24 PF15175.6 ETS85381.1 - 6.7 6.6 14.0 3.5 7.5 4.4 2.5 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 MCU PF04678.13 ETS85381.1 - 7.4 6.6 11.4 7.3 6.6 1.9 2.2 1 1 1 2 2 2 0 Mitochondrial calcium uniporter MctB PF11382.8 ETS85381.1 - 8.1 6.1 9.8 4.4 6.9 1.2 2.9 1 1 2 3 3 3 0 Copper transport outer membrane protein, MctB Atg14 PF10186.9 ETS85381.1 - 8.8 5.3 19.3 15 4.5 14.4 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_DNA_bd PF12329.8 ETS85381.1 - 9.8 6.3 18.4 1.8 8.6 0.7 3.5 1 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.6 ETS85382.1 - 0.00017 21.4 2.1 0.00017 21.4 2.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) HAP1_N PF04849.13 ETS85382.1 - 0.00027 20.2 0.9 0.00049 19.4 0.9 1.4 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF2353 PF09789.9 ETS85382.1 - 0.00028 20.3 2.6 0.00045 19.7 2.6 1.3 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) ATG16 PF08614.11 ETS85382.1 - 0.0019 18.5 3.7 0.0019 18.5 3.7 1.6 2 0 0 2 2 1 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 ETS85382.1 - 0.0022 18.2 2.2 0.0022 18.2 2.2 1.7 2 1 0 2 2 1 1 TATA element modulatory factor 1 TATA binding CCDC144C PF14915.6 ETS85382.1 - 0.011 14.9 4.3 0.21 10.6 1.7 2.0 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region Uso1_p115_C PF04871.13 ETS85382.1 - 0.017 15.5 1.1 0.035 14.5 1.1 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fez1 PF06818.15 ETS85382.1 - 0.028 14.9 4.8 0.04 14.4 4.8 1.2 1 0 0 1 1 1 0 Fez1 YabA PF06156.13 ETS85382.1 - 0.088 13.5 0.8 0.19 12.4 0.7 1.7 1 1 0 1 1 1 0 Initiation control protein YabA Csm1_N PF18504.1 ETS85382.1 - 0.094 13.1 3.5 0.42 11.0 0.1 2.8 2 1 0 3 3 3 0 Csm1 N-terminal domain Spc7 PF08317.11 ETS85382.1 - 0.1 11.4 2.9 0.06 12.2 1.0 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 ETS85382.1 - 0.15 12.1 0.8 0.49 10.4 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 ETS85382.1 - 0.25 10.5 0.4 0.37 10.0 0.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 ETS85382.1 - 0.35 10.9 6.8 0.78 9.8 4.7 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 ETS85382.1 - 0.37 10.9 4.6 0.2 11.8 2.2 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Pox_A_type_inc PF04508.12 ETS85382.1 - 0.6 10.1 5.9 1.1 9.3 0.0 3.4 4 0 0 4 4 3 0 Viral A-type inclusion protein repeat Atg14 PF10186.9 ETS85382.1 - 0.64 9.1 8.1 1.2 8.2 4.2 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 KfrA_N PF11740.8 ETS85382.1 - 0.78 10.4 2.9 11 6.8 3.1 2.1 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Golgin_A5 PF09787.9 ETS85382.1 - 1 8.8 5.7 1.9 7.9 5.7 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 ZapB PF06005.12 ETS85382.1 - 1.1 9.7 6.6 4 8.0 3.3 2.3 1 1 1 2 2 2 0 Cell division protein ZapB JIP_LZII PF16471.5 ETS85382.1 - 1.5 9.0 6.1 11 6.3 1.3 2.8 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II DivIC PF04977.15 ETS85382.1 - 1.6 8.5 5.7 1.1 9.1 0.6 2.5 2 1 1 3 3 3 0 Septum formation initiator Cep57_CLD_2 PF14197.6 ETS85382.1 - 5.9 7.0 12.2 1.1 9.3 7.9 1.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 MIP PF00230.20 ETS85383.1 - 1.7e-43 148.9 16.2 2.1e-43 148.6 16.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein Pec_lyase_C PF00544.19 ETS85384.1 - 1.6e-12 47.5 4.7 1.6e-12 47.5 4.7 2.8 2 1 0 2 2 2 1 Pectate lyase CBM_1 PF00734.18 ETS85384.1 - 1.1e-10 41.3 15.0 1.1e-10 41.3 15.0 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Beta_helix PF13229.6 ETS85384.1 - 5.9e-06 26.2 6.3 0.00032 20.6 6.4 2.3 1 1 0 1 1 1 1 Right handed beta helix region AA_permease PF00324.21 ETS85386.1 - 2.1e-131 438.8 45.2 2.7e-131 438.5 45.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS85386.1 - 9.9e-35 120.2 50.8 1.2e-34 119.9 50.8 1.0 1 0 0 1 1 1 1 Amino acid permease YrhC PF14143.6 ETS85386.1 - 0.24 11.5 3.2 17 5.6 1.0 3.0 2 0 0 2 2 2 0 YrhC-like protein DUF4781 PF16013.5 ETS85386.1 - 1.9 7.2 4.9 0.48 9.2 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) AAA_16 PF13191.6 ETS85387.1 - 6.2e-09 36.5 0.1 2.5e-08 34.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 ETS85387.1 - 4.5e-07 30.0 0.0 7.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 ETS85387.1 - 0.0055 16.3 0.2 0.037 13.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 ETS85387.1 - 0.021 14.6 0.1 0.042 13.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glycos_transf_2 PF00535.26 ETS85387.1 - 0.11 12.2 0.3 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 AAA_7 PF12775.7 ETS85387.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Spem1 PF15670.5 ETS85389.1 - 0.046 13.3 8.7 0.056 13.0 8.7 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 CDC27 PF09507.10 ETS85389.1 - 0.15 11.4 42.4 0.19 11.1 42.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.13 ETS85389.1 - 0.23 11.4 24.4 0.28 11.2 24.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit XRN_M PF17846.1 ETS85389.1 - 0.45 9.4 21.2 0.51 9.2 21.2 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Presenilin PF01080.17 ETS85389.1 - 1.2 7.8 27.6 1.6 7.4 27.6 1.2 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 ETS85389.1 - 3.2 5.8 22.1 3.5 5.6 22.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 ETS85389.1 - 3.6 6.5 22.6 4.3 6.3 22.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 ETS85389.1 - 4.6 5.9 21.4 5.2 5.7 21.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MMR1 PF08505.10 ETS85389.1 - 5.8 7.1 21.5 7.7 6.7 21.5 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Nucleo_P87 PF07267.11 ETS85389.1 - 7.1 5.4 19.2 8.6 5.1 19.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4551 PF15087.6 ETS85389.1 - 7.3 5.3 15.2 8.1 5.1 15.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Sod_Fe_C PF02777.18 ETS85390.1 - 6.6e-35 119.4 0.1 1.2e-34 118.5 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ETS85390.1 - 2.3e-32 111.3 3.3 2.5e-32 111.2 0.8 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Tyrosinase PF00264.20 ETS85391.1 - 1.5e-34 120.2 6.6 2.3e-34 119.6 6.6 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase p450 PF00067.22 ETS85392.1 - 9e-17 61.0 0.0 1.2e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 ETS85393.1 - 9.7e-15 54.8 0.0 1.4e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS85393.1 - 3.2e-07 30.2 0.0 0.017 15.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 ETS85393.1 - 6.7e-07 30.0 0.0 3e-06 27.9 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS85393.1 - 2.5e-06 28.1 0.0 8.7e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS85393.1 - 7.1e-05 23.4 0.0 0.00016 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 ETS85393.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 ETS85393.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Phosphodiest PF01663.22 ETS85394.1 - 2.4e-33 116.2 0.0 5.8e-33 114.9 0.0 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Fungal_trans PF04082.18 ETS85395.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Gal-3-0_sulfotr PF06990.11 ETS85395.1 - 0.063 12.2 0.8 0.73 8.6 0.0 2.0 2 0 0 2 2 2 0 Galactose-3-O-sulfotransferase Zn_clus PF00172.18 ETS85396.1 - 3.3e-10 39.9 8.1 6.1e-10 39.1 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Baculo_p26 PF04766.12 ETS85397.1 - 0.13 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus p26 protein NUP PF06516.11 ETS85398.1 - 1.4e-124 415.4 0.2 1.7e-124 415.2 0.2 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) HATPase_c PF02518.26 ETS85400.1 - 1.4e-21 77.1 0.1 1.8e-20 73.5 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ETS85400.1 - 4.9e-19 68.5 0.0 2e-18 66.6 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 ETS85400.1 - 2.4e-10 40.3 0.0 6.3e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF4900 PF16241.5 ETS85400.1 - 0.15 12.4 0.0 4.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4900) Pec_lyase_C PF00544.19 ETS85401.1 - 9.8e-15 54.7 7.1 8.2e-13 48.4 7.1 2.5 1 1 0 1 1 1 1 Pectate lyase Big_3_4 PF13754.6 ETS85401.1 - 0.09 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function Isochorismatase PF00857.20 ETS85402.1 - 2.6e-23 83.1 0.1 4e-23 82.5 0.1 1.3 1 0 0 1 1 1 1 Isochorismatase family HEAT_2 PF13646.6 ETS85405.1 - 0.079 13.4 4.5 0.14 12.6 0.2 3.6 4 0 0 4 4 4 0 HEAT repeats HEAT PF02985.22 ETS85405.1 - 0.084 13.2 10.8 0.34 11.3 0.0 5.5 6 0 0 6 6 6 0 HEAT repeat VHS PF00790.19 ETS85405.1 - 0.13 12.1 0.0 0.99 9.3 0.0 2.4 2 0 0 2 2 2 0 VHS domain Cnd1 PF12717.7 ETS85405.1 - 0.15 12.1 0.5 1.4 8.9 0.1 3.0 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 PXA PF02194.15 ETS85405.1 - 0.45 10.5 2.6 5.1 7.0 0.0 3.5 4 0 0 4 4 4 0 PXA domain Trypan_PARP PF05887.11 ETS85405.1 - 0.68 9.9 20.0 3 7.8 20.0 2.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) mRNA_cap_enzyme PF01331.19 ETS85406.1 - 1e-56 191.9 0.0 1.4e-56 191.5 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 ETS85406.1 - 6.1e-34 116.9 0.1 9.6e-34 116.3 0.1 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 ETS85406.1 - 4e-07 29.9 0.0 0.0055 16.4 0.0 2.5 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 ETS85406.1 - 0.00067 20.0 0.2 0.0013 19.0 0.1 1.6 2 0 0 2 2 2 1 RNA ligase FtsQ PF03799.15 ETS85406.1 - 0.092 13.6 0.0 0.18 12.7 0.0 1.5 1 0 0 1 1 1 0 Cell division protein FtsQ MFS_1 PF07690.16 ETS85407.1 - 4.5e-32 111.4 41.7 3.4e-31 108.5 42.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 ETS85408.1 - 2.3e-09 36.6 2.2 4e-09 35.8 2.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain AA_permease_2 PF13520.6 ETS85409.1 - 4.6e-71 239.9 40.4 5.8e-71 239.5 40.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS85409.1 - 4.5e-14 51.9 36.1 5.7e-14 51.6 36.1 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 ETS85409.1 - 1.2e-05 24.2 16.8 1.2e-05 24.2 16.8 2.0 1 1 1 2 2 2 1 Transmembrane amino acid transporter protein NmrA PF05368.13 ETS85410.1 - 8e-10 38.7 0.2 1.2e-09 38.1 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family Peripla_BP_4 PF13407.6 ETS85410.1 - 1.9e-06 27.7 0.4 1e-05 25.3 0.1 2.0 1 1 1 2 2 2 1 Periplasmic binding protein domain NAD_binding_10 PF13460.6 ETS85410.1 - 5.3e-06 26.5 0.2 9e-06 25.7 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS85410.1 - 0.0098 15.4 0.0 0.25 10.8 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Aa_trans PF01490.18 ETS85411.1 - 1.2e-49 169.1 35.9 1.4e-49 168.9 35.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3483 PF11982.8 ETS85411.1 - 0.043 13.5 3.0 0.66 9.6 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3483) Asparaginase PF00710.20 ETS85413.1 - 1.5e-52 177.9 0.7 2.1e-52 177.5 0.7 1.1 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 ETS85413.1 - 3.4e-19 69.1 0.1 1.5e-18 67.0 0.0 2.2 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain DUF3632 PF12311.8 ETS85414.1 - 2.5e-33 116.0 1.8 2.5e-33 116.0 1.8 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) MFS_1 PF07690.16 ETS85415.1 - 3.2e-28 98.7 62.6 9.1e-21 74.2 32.3 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Methyltransf_2 PF00891.18 ETS85416.1 - 6.8e-17 61.5 0.0 1.3e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain zf-C2H2 PF00096.26 ETS85417.1 - 0.096 13.2 1.6 0.096 13.2 1.6 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type adh_short PF00106.25 ETS85418.1 - 1.4e-23 83.4 0.1 4.2e-20 72.0 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS85418.1 - 6.2e-13 48.9 0.1 2.4e-10 40.4 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS85418.1 - 7.6e-11 42.2 0.1 1.6e-10 41.2 0.1 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 ETS85418.1 - 0.0098 15.4 0.1 0.015 14.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyoxalase_4 PF13669.6 ETS85418.1 - 0.029 14.6 0.0 0.078 13.3 0.0 1.8 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YAcAr PF10686.9 ETS85418.1 - 0.058 13.4 0.4 1.4 9.0 0.0 2.9 4 0 0 4 4 4 0 YspA, cpYpsA-related SLOG family Glyco_hydro_28 PF00295.17 ETS85421.1 - 3.6e-49 167.6 10.2 5.5e-49 167.0 10.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 ABC_membrane PF00664.23 ETS85422.1 - 6.2e-41 140.9 14.6 7.8e-41 140.5 14.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ETS85422.1 - 2e-33 115.8 0.0 3.5e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ETS85422.1 - 6.7e-06 25.7 0.0 0.00068 19.1 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ETS85422.1 - 0.00012 22.4 0.1 0.0019 18.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 ETS85422.1 - 0.00018 21.5 0.0 0.0047 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 ETS85422.1 - 0.00045 20.3 0.0 0.0015 18.6 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ETS85422.1 - 0.00049 20.5 0.0 0.0013 19.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 ETS85422.1 - 0.00066 19.5 0.1 0.0017 18.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 ETS85422.1 - 0.0019 18.2 0.0 0.054 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ETS85422.1 - 0.0053 16.7 0.0 0.024 14.6 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 ETS85422.1 - 0.012 15.3 0.1 0.04 13.7 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 ETS85422.1 - 0.015 15.7 0.0 0.12 12.8 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ETS85422.1 - 0.018 14.6 0.0 0.051 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ETS85422.1 - 0.02 15.1 0.0 0.052 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 ETS85422.1 - 0.025 14.3 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 ETS85422.1 - 0.034 14.1 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 ETS85422.1 - 0.04 14.5 0.0 0.16 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ETS85422.1 - 0.047 14.2 0.0 0.095 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 ETS85422.1 - 0.062 12.1 0.2 3.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class SbcCD_C PF13558.6 ETS85422.1 - 0.074 13.3 0.3 1.3 9.3 0.3 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 ETS85422.1 - 0.084 13.0 0.1 0.2 11.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 ETS85422.1 - 0.17 11.8 0.2 0.62 10.0 0.0 2.0 3 0 0 3 3 2 0 NACHT domain Pyr_redox_2 PF07992.14 ETS85423.1 - 2e-35 122.5 0.0 2.5e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS85423.1 - 2.1e-14 53.8 0.2 9.6e-12 45.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS85423.1 - 1.1e-05 25.3 0.3 0.42 10.1 0.0 3.4 4 0 0 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.6 ETS85423.1 - 6.8e-05 22.2 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ETS85423.1 - 7.4e-05 22.1 0.0 0.00018 20.8 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ETS85423.1 - 0.0063 16.9 0.2 1.4 9.4 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding Trp_halogenase PF04820.14 ETS85423.1 - 0.0089 14.9 0.6 6.8 5.4 0.1 3.0 2 1 1 3 3 3 1 Tryptophan halogenase NAD_binding_9 PF13454.6 ETS85423.1 - 0.016 15.2 2.4 33 4.4 0.0 4.0 3 1 1 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ETS85423.1 - 0.02 14.0 0.0 2.5 7.1 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 ETS85423.1 - 0.025 13.3 0.3 1 8.0 0.1 2.6 2 1 0 3 3 3 0 HI0933-like protein NAD_binding_8 PF13450.6 ETS85423.1 - 0.026 14.8 0.0 6.8 7.0 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 ETS85423.1 - 0.04 14.2 0.2 2 8.7 0.0 2.7 3 0 0 3 3 3 0 TrkA-N domain Trp_ring PF18669.1 ETS85423.1 - 0.065 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Trimeric autotransporter adhesin Trp ring domain Serpin PF00079.20 ETS85423.1 - 0.22 10.8 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) Glyco_hydro_115 PF15979.5 ETS85424.1 - 1.4e-133 445.6 0.1 1.9e-133 445.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 ETS85424.1 - 4.6e-41 140.5 0.0 7.7e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain MFS_1 PF07690.16 ETS85425.1 - 3.3e-35 121.7 27.0 3.3e-35 121.7 27.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SpoVAB PF13782.6 ETS85425.1 - 0.0011 19.2 5.1 0.0089 16.3 0.8 2.8 2 0 0 2 2 2 2 Stage V sporulation protein AB MR_MLE_C PF13378.6 ETS85426.1 - 2.8e-44 151.3 0.3 3.9e-44 150.8 0.3 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ETS85426.1 - 0.046 13.9 0.0 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain HUN PF08729.10 ETS85427.1 - 4.3e-08 33.0 0.7 1.2e-07 31.6 0.7 1.8 1 0 0 1 1 1 1 HPC2 and ubinuclein domain RPAP1_C PF08620.10 ETS85428.1 - 5.2e-28 96.9 0.0 1.1e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 ETS85428.1 - 5.5e-19 67.7 2.0 1e-18 66.8 2.0 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal GPP34 PF05719.11 ETS85429.1 - 6.3e-69 232.1 0.1 7.6e-69 231.8 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) DUF1907 PF08925.11 ETS85430.1 - 2e-109 365.4 0.0 2.3e-109 365.2 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) PA_decarbox PF05870.11 ETS85431.1 - 1.7e-07 31.0 0.6 3e-07 30.2 0.5 1.6 1 1 0 1 1 1 1 Phenolic acid decarboxylase (PAD) Sugar_tr PF00083.24 ETS85432.1 - 5.1e-73 246.5 24.4 5.9e-73 246.3 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS85432.1 - 1.1e-30 106.8 44.5 2.7e-28 98.9 26.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_membrane PF00664.23 ETS85432.1 - 0.22 11.1 15.7 1.4 8.5 3.2 3.6 3 0 0 3 3 3 0 ABC transporter transmembrane region adh_short_C2 PF13561.6 ETS85433.1 - 1.7e-43 148.9 0.0 4.8e-37 127.8 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS85433.1 - 3.4e-38 131.1 0.0 4.1e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS85433.1 - 1.1e-13 51.6 0.0 1.6e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS85433.1 - 0.0049 16.4 0.1 0.021 14.3 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 ETS85434.1 - 3.1e-64 216.7 0.5 3.6e-64 216.5 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS85434.1 - 5.5e-54 182.6 0.9 6.8e-54 182.3 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS85434.1 - 3.6e-10 40.0 0.2 5e-10 39.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS85434.1 - 1.3e-05 24.8 0.0 1.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 ETS85434.1 - 0.00082 19.3 1.2 0.0013 18.6 1.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ETS85434.1 - 0.017 15.3 0.3 0.033 14.4 0.3 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 ETS85434.1 - 0.02 14.3 0.1 0.03 13.7 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RNA_pol_Rpb1_4 PF05000.17 ETS85434.1 - 0.063 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 ADH_zinc_N PF00107.26 ETS85434.1 - 0.063 13.3 0.7 0.14 12.1 0.7 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 3Beta_HSD PF01073.19 ETS85434.1 - 0.097 11.7 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AdoHcyase_NAD PF00670.21 ETS85434.1 - 0.12 12.5 0.4 0.26 11.4 0.4 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glyco_hydro_72 PF03198.14 ETS85436.1 - 3.3e-123 411.0 4.0 5.1e-123 410.3 4.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 ETS85436.1 - 9.5e-24 83.9 4.9 2.7e-23 82.4 4.9 1.9 1 0 0 1 1 1 1 X8 domain Miga PF10265.9 ETS85436.1 - 2.6 6.9 4.0 3.8 6.4 4.0 1.2 1 0 0 1 1 1 0 Mitoguardin SOG2 PF10428.9 ETS85436.1 - 4.8 6.3 14.2 7.1 5.7 14.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein His_Phos_2 PF00328.22 ETS85437.1 - 2.4e-21 76.5 0.0 7.4e-21 74.9 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF4037 PF13228.6 ETS85437.1 - 0.061 14.1 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4037) Red1 PF07964.11 ETS85439.1 - 0.96 7.6 11.6 1.1 7.4 11.6 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Borrelia_P83 PF05262.11 ETS85439.1 - 2.9 6.3 15.9 3 6.2 15.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PBP1_TM PF14812.6 ETS85439.1 - 7.8 6.9 12.8 11 6.5 4.8 2.3 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4554 PF15091.6 ETS85439.1 - 8.4 5.2 6.8 10 4.9 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) LRRC37AB_C PF14914.6 ETS85441.1 - 0.039 13.9 1.1 0.084 12.8 0.9 1.7 1 1 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain MFS_1 PF07690.16 ETS85443.1 - 1.8e-47 162.0 34.5 3.7e-40 137.9 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ETS85443.1 - 9.3e-05 20.9 7.7 0.0011 17.4 1.6 2.9 3 1 1 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 ETS85443.1 - 0.15 10.8 15.6 0.1 11.5 5.0 3.4 3 1 0 3 3 3 0 MFS_1 like family EphA2_TM PF14575.6 ETS85444.1 - 0.018 15.9 0.7 0.08 13.8 0.7 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gram_pos_anchor PF00746.21 ETS85444.1 - 0.047 13.6 3.5 0.12 12.3 3.5 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif YajC PF02699.15 ETS85444.1 - 4.4 7.2 5.0 2.6 8.0 0.1 2.2 2 0 0 2 2 2 0 Preprotein translocase subunit Cupin_2 PF07883.11 ETS85445.1 - 1.4e-10 40.7 0.8 1.4e-10 40.7 0.8 1.9 3 0 0 3 3 3 1 Cupin domain Cupin_1 PF00190.22 ETS85445.1 - 4.7e-07 29.5 0.0 6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 ETS85445.1 - 0.0027 17.6 0.3 0.0049 16.8 0.1 1.5 2 0 0 2 2 2 1 AraC-like ligand binding domain JmjC PF02373.22 ETS85445.1 - 0.013 16.0 0.2 0.1 13.0 0.2 2.1 1 1 0 1 1 1 0 JmjC domain, hydroxylase FdtA PF05523.11 ETS85445.1 - 0.022 14.5 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal GPI PF06560.11 ETS85445.1 - 0.03 13.6 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) SRR1 PF07985.12 ETS85446.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 SRR1 SURF6 PF04935.12 ETS85447.1 - 2.3e-50 171.2 42.1 2.3e-50 171.2 42.1 4.2 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 ETS85447.1 - 2.2e-17 63.4 1.8 2.2e-17 63.4 1.8 7.1 5 1 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 DUF3824 PF12868.7 ETS85448.1 - 2.7e-06 28.1 25.2 0.014 16.1 1.3 5.2 4 1 1 5 5 5 3 Domain of unknwon function (DUF3824) NCE101 PF11654.8 ETS85448.1 - 0.0019 17.9 0.1 1.8 8.3 0.0 2.6 2 0 0 2 2 2 2 Non-classical export protein 1 ApbA PF02558.16 ETS85448.1 - 0.027 14.1 0.1 0.063 12.9 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF3918 PF13056.6 ETS85448.1 - 0.12 12.0 0.0 0.12 12.0 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3918) NAD_binding_8 PF13450.6 ETS85448.1 - 2.1 8.7 11.9 0.92 9.8 0.2 4.6 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.16 ETS85449.1 - 1.8e-41 142.3 48.3 5.6e-41 140.6 48.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Isochorismatase PF00857.20 ETS85451.1 - 2.4e-13 50.7 0.0 3.6e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Glyco_hydro_125 PF06824.11 ETS85452.1 - 2.9e-169 563.3 0.0 3.4e-169 563.1 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) DUF2434 PF10361.9 ETS85453.1 - 1.7e-132 440.9 6.2 2.2e-132 440.5 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) Sporozoite_P67 PF05642.11 ETS85453.1 - 1.5 6.8 7.5 2 6.4 7.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-C2H2 PF00096.26 ETS85454.1 - 5.7e-06 26.5 11.6 0.0025 18.2 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ETS85454.1 - 0.00027 21.2 3.8 0.00027 21.2 3.8 2.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ETS85454.1 - 0.00033 21.2 11.2 0.071 14.0 2.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ETS85454.1 - 1.1 9.1 5.6 2.4 8.0 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain AtuA PF07287.11 ETS85455.1 - 2.5e-130 434.3 0.3 3e-130 434.0 0.3 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Polysacc_deac_1 PF01522.21 ETS85456.1 - 6.3e-27 93.9 0.0 9.2e-27 93.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ETS85456.1 - 6.3e-08 32.2 0.0 8e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Zn_clus PF00172.18 ETS85457.1 - 2.6e-08 33.9 10.2 4e-08 33.2 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS85457.1 - 0.00031 19.9 0.5 0.00075 18.6 0.5 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Cnd1 PF12717.7 ETS85457.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Glyco_hydro_61 PF03443.14 ETS85458.1 - 5.3e-60 202.9 0.0 6.7e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 ETS85458.1 - 0.044 14.0 0.6 0.7 10.2 0.0 2.9 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Cpn60_TCP1 PF00118.24 ETS85459.1 - 9.5e-164 545.6 0.1 1.1e-163 545.5 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Prenylcys_lyase PF07156.14 ETS85460.1 - 1.8e-86 290.6 0.0 2.4e-86 290.1 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 ETS85460.1 - 1.7e-12 47.3 0.1 1.7e-12 47.3 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ETS85460.1 - 4.7e-10 39.4 0.0 1.4e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 ETS85460.1 - 3.1e-06 27.0 0.5 8.1e-06 25.6 0.4 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS85460.1 - 1.7e-05 24.8 0.4 0.0011 19.0 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ETS85460.1 - 0.0017 17.6 0.2 0.011 15.0 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 ETS85461.1 - 8e-39 133.1 0.0 1.7e-38 132.1 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS85461.1 - 1.5e-21 77.0 0.0 2.8e-21 76.1 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS85461.1 - 8.8e-09 35.5 0.0 1.3e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS85461.1 - 0.00012 21.7 0.0 0.00018 21.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 ETS85461.1 - 0.00037 21.0 0.2 0.0009 19.8 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 ETS85461.1 - 0.00083 18.6 0.1 0.0012 18.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 ETS85461.1 - 0.013 15.4 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 ETS85461.1 - 0.016 14.6 0.2 0.022 14.1 0.2 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 ETS85461.1 - 0.028 14.5 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 ETS85461.1 - 0.082 12.8 0.2 0.2 11.5 0.2 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ETS85461.1 - 0.1 12.9 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain VID27 PF08553.10 ETS85462.1 - 4e-191 634.7 0.0 5.1e-191 634.3 0.0 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 ETS85462.1 - 2.4e-76 255.4 0.1 2.4e-76 255.4 0.1 2.5 2 1 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 ETS85462.1 - 1.4e-44 150.8 3.0 2.6e-44 150.0 1.6 2.2 3 0 0 3 3 3 1 VID27 PH-like domain TFB6 PF17110.5 ETS85462.1 - 0.12 12.1 1.4 1.5 8.5 0.3 2.5 3 0 0 3 3 3 0 Subunit 11 of the general transcription factor TFIIH DNA_pol_phi PF04931.13 ETS85462.1 - 0.19 9.8 7.8 0.31 9.1 7.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 ETS85462.1 - 0.81 7.9 5.5 1.2 7.4 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 ETS85462.1 - 1.4 7.0 11.5 2.1 6.4 11.5 1.2 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 ETS85462.1 - 9 5.6 13.4 16 4.8 13.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Glyco_transf_20 PF00982.21 ETS85463.1 - 2.5e-199 662.9 0.0 2.8e-199 662.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 ETS85463.1 - 0.0081 15.9 0.1 0.049 13.3 0.0 2.1 2 0 0 2 2 2 1 Starch synthase catalytic domain PKD_channel PF08016.12 ETS85464.1 - 0.7 8.5 8.8 3 6.4 2.0 2.3 2 0 0 2 2 2 0 Polycystin cation channel 2-oxoacid_dh PF00198.23 ETS85465.1 - 5.6e-80 268.1 0.0 9.4e-80 267.4 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ETS85465.1 - 1.7e-19 69.4 2.8 3.7e-19 68.3 2.8 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ETS85465.1 - 1.1e-05 25.2 0.5 0.037 13.9 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 ETS85465.1 - 2e-05 25.2 0.6 0.13 13.0 0.1 2.4 1 1 1 2 2 2 2 HlyD family secretion protein RnfC_N PF13375.6 ETS85465.1 - 0.012 15.5 0.3 0.48 10.4 0.0 2.8 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain DUF3614 PF12267.8 ETS85465.1 - 0.036 14.5 1.0 0.13 12.7 0.0 2.3 2 1 0 3 3 2 0 Protein of unknown function (DUF3614) GCV_H PF01597.19 ETS85465.1 - 0.04 13.8 0.5 0.11 12.4 0.4 1.8 1 1 0 1 1 1 0 Glycine cleavage H-protein DUF1387 PF07139.11 ETS85465.1 - 0.13 12.0 7.3 0.19 11.4 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Presenilin PF01080.17 ETS85465.1 - 0.62 8.8 5.7 0.77 8.5 5.7 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 ETS85465.1 - 1.1 8.0 7.5 1.5 7.6 7.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Trypan_PARP PF05887.11 ETS85465.1 - 2 8.4 18.2 3.6 7.6 18.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2052 PF09747.9 ETS85465.1 - 2.4 8.2 8.2 3.6 7.7 8.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) FAM76 PF16046.5 ETS85465.1 - 5.9 6.2 10.8 23 4.2 7.4 2.1 1 1 0 2 2 2 0 FAM76 protein CDC45 PF02724.14 ETS85465.1 - 9.4 4.4 7.2 12 4.0 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Histone_H2A_C PF16211.5 ETS85467.1 - 3.2e-21 74.8 3.1 5.6e-21 74.0 3.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 ETS85467.1 - 7.2e-17 62.0 0.0 9.4e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ETS85467.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DLIC PF05783.11 ETS85467.1 - 0.21 10.4 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Histone PF00125.24 ETS85468.1 - 5.1e-21 75.4 2.7 6.4e-21 75.1 2.7 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ETS85468.1 - 4.1e-05 23.8 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 ETS85468.1 - 0.00025 21.5 0.0 0.00043 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 ETS85468.1 - 0.033 13.9 0.1 0.076 12.7 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain R3H PF01424.22 ETS85469.1 - 4e-11 42.7 0.0 9.7e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 ETS85469.1 - 6.1e-08 32.4 1.5 1.6e-07 31.1 1.5 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ETS85469.1 - 1.9 8.6 5.9 0.3 11.2 0.6 2.5 2 0 0 2 2 2 0 G-patch domain Peptidase_C54 PF03416.19 ETS85470.1 - 1.1e-92 310.4 0.0 1.4e-92 310.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 DnaJ PF00226.31 ETS85471.1 - 6.2e-24 83.9 2.8 6.2e-24 83.9 2.8 2.1 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 ETS85471.1 - 1.4e-10 41.2 3.0 1.4e-10 41.2 3.0 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ETS85471.1 - 8.9e-09 35.5 7.9 2.5e-08 34.1 2.7 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 ETS85471.1 - 4.9e-06 26.8 5.9 0.00053 20.3 2.0 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 ETS85471.1 - 3e-05 24.5 3.1 0.067 14.1 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ETS85471.1 - 0.00012 22.3 4.3 0.028 14.9 0.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type Actin_micro PF17003.5 ETS85471.1 - 0.027 13.7 0.9 0.54 9.4 0.1 2.2 2 0 0 2 2 2 0 Putative actin-like family zf-C2H2_6 PF13912.6 ETS85471.1 - 0.049 13.6 7.1 1.5 8.9 1.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-LYAR PF08790.11 ETS85471.1 - 0.091 12.7 0.2 0.2 11.6 0.2 1.6 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger RPT PF13446.6 ETS85471.1 - 0.1 12.5 0.1 0.49 10.4 0.1 2.2 1 1 0 1 1 1 0 A repeated domain in UCH-protein DUF2256 PF10013.9 ETS85471.1 - 0.97 9.6 3.8 8.3 6.6 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) SPX PF03105.19 ETS85472.1 - 9.5e-44 150.9 1.7 4.8e-43 148.6 1.7 1.8 1 1 0 1 1 1 1 SPX domain zf-C3HC4 PF00097.25 ETS85472.1 - 1.3e-07 31.3 7.9 3e-07 30.2 7.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS85472.1 - 4.4e-07 29.7 5.1 7.8e-07 28.9 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ETS85472.1 - 4.7e-06 26.7 8.5 1.1e-05 25.4 8.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 ETS85472.1 - 7.4e-06 25.7 8.6 1.4e-05 24.8 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ETS85472.1 - 8.5e-06 26.0 9.2 1.9e-05 24.9 9.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ETS85472.1 - 1.3e-05 25.1 6.6 3.2e-05 23.8 6.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ETS85472.1 - 8.5e-05 22.4 8.1 0.00025 20.9 8.2 1.8 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ETS85472.1 - 0.004 17.0 8.4 0.024 14.5 8.7 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 ETS85472.1 - 0.079 12.8 3.0 0.22 11.4 3.0 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 ETS85472.1 - 0.13 12.1 7.3 0.04 13.7 3.9 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 ETS85472.1 - 0.71 9.6 5.8 0.94 9.2 2.0 2.3 2 0 0 2 2 2 0 P-11 zinc finger DZR PF12773.7 ETS85472.1 - 0.81 9.8 3.4 3.9 7.6 3.8 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-Nse PF11789.8 ETS85472.1 - 0.93 9.4 3.6 2.4 8.1 3.6 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 ETS85472.1 - 1.3 9.4 8.4 3.9 7.9 8.4 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_5 PF17121.5 ETS85472.1 - 7.1 6.6 6.7 24 4.9 6.7 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cys_Met_Meta_PP PF01053.20 ETS85473.1 - 1.9e-34 118.8 0.0 2.9e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ETS85473.1 - 0.09 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Mito_carr PF00153.27 ETS85475.1 - 5.8e-65 215.3 7.9 3.2e-21 75.1 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ETS85475.1 - 0.013 14.6 4.9 0.064 12.4 0.2 2.9 1 1 2 3 3 3 0 Gammaproteobacterial serine protease Cwf_Cwc_15 PF04889.12 ETS85477.1 - 0.0043 16.8 16.6 0.0094 15.7 16.6 1.6 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein RPN2_C PF18004.1 ETS85477.1 - 0.0063 16.4 0.7 0.012 15.5 0.7 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain DUF2457 PF10446.9 ETS85477.1 - 0.01 15.1 21.7 0.01 15.1 21.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Nop14 PF04147.12 ETS85477.1 - 0.058 11.6 11.0 0.083 11.1 11.0 1.3 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 ETS85477.1 - 0.067 12.5 17.3 0.095 12.0 17.3 1.2 1 0 0 1 1 1 0 NOA36 protein LigT_PEase PF02834.16 ETS85477.1 - 0.1 12.8 0.5 33 4.8 0.0 3.3 2 0 0 2 2 2 0 LigT like Phosphoesterase Vfa1 PF08432.10 ETS85477.1 - 0.31 11.4 4.4 1 9.7 4.4 1.8 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_3_Rpc31 PF11705.8 ETS85477.1 - 0.36 11.1 16.7 0.75 10.0 16.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 ETS85477.1 - 0.54 9.5 12.6 0.07 12.5 8.3 1.8 2 0 0 2 2 2 0 BUD22 DUF2796 PF10986.8 ETS85477.1 - 0.73 9.8 5.7 1.5 8.8 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) DUF1993 PF09351.10 ETS85477.1 - 0.8 9.8 3.2 15 5.7 0.1 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF1993) CENP-B_dimeris PF09026.10 ETS85477.1 - 0.89 10.0 18.8 2 8.8 18.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SGT1 PF07093.11 ETS85477.1 - 1.2 7.5 8.0 1.9 6.8 8.0 1.3 1 0 0 1 1 1 0 SGT1 protein GCIP PF13324.6 ETS85477.1 - 1.3 8.6 8.8 2.5 7.6 8.8 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting FYDLN_acid PF09538.10 ETS85477.1 - 1.9 9.2 20.8 6.3 7.5 20.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RRN3 PF05327.11 ETS85477.1 - 2.1 6.8 11.9 2.9 6.3 11.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RXT2_N PF08595.11 ETS85477.1 - 3.3 7.7 10.3 6.1 6.8 10.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 ETS85477.1 - 3.9 5.5 22.7 5.8 4.9 22.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 ETS85477.1 - 5 5.3 15.8 7.2 4.8 15.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 ETS85477.1 - 7.5 6.3 14.1 3.7 7.3 8.1 3.0 3 1 0 3 3 3 0 Pox virus Ag35 surface protein PBP1_TM PF14812.6 ETS85477.1 - 7.7 7.0 19.1 21 5.5 19.1 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DnaJ PF00226.31 ETS85478.1 - 1.3e-21 76.5 3.1 1.3e-21 76.4 0.7 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_9 PF13371.6 ETS85478.1 - 1.1e-14 54.3 0.1 1.5e-05 25.1 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 ETS85478.1 - 3.2e-13 48.9 0.1 0.00022 20.9 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 ETS85478.1 - 3e-11 42.6 0.1 0.0035 17.4 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 ETS85478.1 - 1e-10 41.5 9.4 0.0027 18.4 0.4 5.4 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ETS85478.1 - 3.7e-10 39.1 12.7 0.022 14.9 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 ETS85478.1 - 3.4e-09 36.4 0.9 0.00016 21.8 0.1 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS85478.1 - 6.7e-09 36.1 7.5 0.0075 16.8 0.1 5.2 3 1 1 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 ETS85478.1 - 5.3e-07 29.9 8.7 0.5 11.1 0.1 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 ETS85478.1 - 6.2e-07 29.0 1.8 0.0013 18.4 0.4 4.5 4 2 2 6 6 5 2 TPR repeat PknG_TPR PF16918.5 ETS85478.1 - 1.2e-06 27.5 0.1 0.0004 19.2 0.0 2.7 1 1 0 2 2 2 1 Protein kinase G tetratricopeptide repeat TPR_7 PF13176.6 ETS85478.1 - 2.8e-05 23.8 1.8 0.0017 18.2 0.3 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 ETS85478.1 - 4.5e-05 24.0 10.0 0.0032 18.1 0.2 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS85478.1 - 0.00017 21.7 10.6 0.67 10.2 0.3 5.4 4 1 3 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ETS85478.1 - 0.012 15.9 0.5 0.012 15.9 0.5 4.5 4 2 1 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 ETS85478.1 - 0.088 13.2 1.6 1.1 9.7 0.0 3.5 3 3 1 4 4 4 0 Tetratricopeptide repeat HrpB2 PF09487.10 ETS85478.1 - 0.095 13.1 0.1 0.26 11.7 0.1 1.7 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) Alkyl_sulf_dimr PF14863.6 ETS85478.1 - 0.12 12.8 3.2 6.5 7.2 0.0 3.4 2 1 0 3 3 3 0 Alkyl sulfatase dimerisation EF1_GNE PF00736.19 ETS85478.1 - 0.19 12.0 1.0 0.44 10.7 1.0 1.6 1 0 0 1 1 1 0 EF-1 guanine nucleotide exchange domain BTAD PF03704.17 ETS85478.1 - 0.34 11.3 4.1 9.2 6.7 0.0 3.7 2 1 2 4 4 4 0 Bacterial transcriptional activator domain DUF4795 PF16043.5 ETS85478.1 - 0.42 10.2 8.5 2.6 7.6 4.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) PCRF PF03462.18 ETS85478.1 - 0.57 10.0 5.8 0.46 10.3 0.8 2.4 2 0 0 2 2 2 0 PCRF domain TPR_21 PF09976.9 ETS85478.1 - 7.3 6.2 17.6 1.7 8.3 2.6 4.0 3 2 1 4 4 3 0 Tetratricopeptide repeat-like domain Vac14_Fig4_bd PF11916.8 ETS85479.1 - 3.4e-82 274.4 8.8 7.5e-82 273.3 8.8 1.6 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 ETS85479.1 - 3.8e-43 146.0 0.0 2.2e-41 140.4 0.0 3.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 ETS85479.1 - 4.7e-08 33.4 2.3 0.0017 18.8 0.1 4.7 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 ETS85479.1 - 1.2e-06 28.7 0.4 0.005 16.9 0.5 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ETS85479.1 - 1.6e-06 27.9 0.3 0.002 18.2 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 ETS85479.1 - 0.0035 17.7 0.1 4.6 7.7 0.0 4.5 4 0 0 4 4 4 1 HEAT repeats FA_desaturase PF00487.24 ETS85480.1 - 5.2e-26 92.0 25.7 8e-26 91.4 25.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ETS85480.1 - 7e-08 32.5 0.0 1.4e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pyr_redox_2 PF07992.14 ETS85481.1 - 4.5e-70 236.2 6.1 6e-70 235.8 6.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ETS85481.1 - 2.9e-41 140.1 0.0 9.3e-41 138.5 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ETS85481.1 - 2.2e-21 76.2 10.6 9e-20 71.0 1.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS85481.1 - 9.8e-11 41.7 3.5 5.7e-06 26.5 0.5 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ETS85481.1 - 2e-09 37.3 9.4 4.4e-09 36.2 0.4 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 ETS85481.1 - 6.2e-08 32.1 11.1 1.6e-06 27.5 4.4 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ETS85481.1 - 4.7e-07 29.2 4.1 4.7e-07 29.2 4.1 3.2 3 1 0 4 4 4 1 FAD binding domain DAO PF01266.24 ETS85481.1 - 6.7e-07 29.2 10.4 0.0046 16.6 0.5 4.2 4 0 0 4 4 4 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ETS85481.1 - 9.2e-07 28.4 5.0 0.0078 15.5 0.7 2.8 3 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ETS85481.1 - 5.1e-06 25.9 6.0 2.8e-05 23.5 0.2 2.6 2 1 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 ETS85481.1 - 7.4e-06 25.4 6.5 0.00086 18.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS85481.1 - 1e-05 24.4 14.5 0.00027 19.8 2.8 4.0 4 0 0 4 4 4 1 HI0933-like protein FAD_binding_3 PF01494.19 ETS85481.1 - 0.00013 21.4 6.6 0.012 14.9 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.6 ETS85481.1 - 0.00047 19.4 0.2 0.13 11.3 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 ETS85481.1 - 0.078 12.0 6.4 0.077 12.0 1.1 2.5 2 1 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 ETS85481.1 - 0.26 11.7 6.8 2.1 8.9 0.9 3.0 2 2 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 ETS85481.1 - 2.5 7.9 7.2 0.6 10.0 0.5 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ETS85481.1 - 2.7 7.5 4.7 2.9 7.4 0.2 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.14 ETS85481.1 - 4.5 6.0 7.1 0.55 9.0 1.6 2.0 2 0 0 2 2 2 0 Tryptophan halogenase MIF4G PF02854.19 ETS85482.1 - 1.5e-18 67.2 0.1 2.7e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 ETS85482.1 - 3.8e-10 39.8 0.0 4.9e-09 36.2 0.0 2.7 2 0 0 2 2 2 1 MA3 domain RRM_1 PF00076.22 ETS85483.1 - 5.6e-33 112.6 0.0 1.4e-15 56.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-grasp_2 PF08442.10 ETS85483.1 - 0.0016 18.1 0.0 0.023 14.3 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Limkain-b1 PF11608.8 ETS85483.1 - 0.044 13.8 0.1 2.1 8.5 0.0 3.1 3 1 0 3 3 3 0 Limkain b1 COQ9 PF08511.11 ETS85484.1 - 7.6e-28 96.1 0.1 3.8e-27 93.9 0.1 2.0 2 0 0 2 2 2 1 COQ9 SMC_N PF02463.19 ETS85485.1 - 2.2e-26 92.7 3.6 1.2e-25 90.3 3.6 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ETS85485.1 - 2e-12 47.5 4.1 2e-12 47.5 4.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 ETS85485.1 - 7.4e-12 46.2 28.8 7.4e-12 46.2 28.8 5.2 2 2 0 2 2 1 1 AAA domain AAA_21 PF13304.6 ETS85485.1 - 1.2e-07 31.9 0.1 0.00017 21.5 0.1 2.9 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_hinge PF06470.13 ETS85485.1 - 5.9e-06 26.6 0.0 2e-05 24.9 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain SbcCD_C PF13558.6 ETS85485.1 - 0.00033 20.8 0.0 0.035 14.3 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 ETS85485.1 - 0.00044 19.9 0.0 0.00095 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATG16 PF08614.11 ETS85485.1 - 0.0015 18.8 11.2 0.0015 18.8 11.2 6.2 3 2 3 6 6 5 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 ETS85485.1 - 0.0033 16.4 22.2 0.0033 16.4 22.2 5.0 3 2 2 5 5 5 2 Spc7 kinetochore protein Laminin_II PF06009.12 ETS85485.1 - 0.026 14.5 0.8 0.026 14.5 0.8 6.5 3 2 1 6 6 6 0 Laminin Domain II KIP1 PF07765.12 ETS85485.1 - 0.057 13.5 9.0 0.093 12.9 0.3 5.3 6 0 0 6 6 6 0 KIP1-like protein ABC_tran PF00005.27 ETS85485.1 - 0.11 13.0 0.2 0.11 13.0 0.2 5.7 3 2 0 3 3 2 0 ABC transporter SGT1 PF07093.11 ETS85486.1 - 1.5e-90 304.4 24.1 7.9e-78 262.3 0.0 2.1 1 1 1 2 2 2 2 SGT1 protein AAA PF00004.29 ETS85487.1 - 5.2e-39 133.7 0.0 1e-38 132.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 ETS85487.1 - 7.1e-08 32.3 0.0 3e-07 30.3 0.0 2.1 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 ETS85487.1 - 1.3e-07 31.3 0.0 3.7e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 ETS85487.1 - 2.9e-05 23.8 0.0 6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ETS85487.1 - 4.7e-05 23.7 2.4 0.00059 20.1 0.2 3.2 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.6 ETS85487.1 - 7.8e-05 23.1 0.4 0.002 18.5 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 ETS85487.1 - 0.00042 19.6 0.0 0.00078 18.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 ETS85487.1 - 0.0019 18.2 0.0 0.0053 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ETS85487.1 - 0.0019 18.3 0.0 0.0043 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 ETS85487.1 - 0.0032 17.2 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 ETS85487.1 - 0.0043 16.5 0.1 0.0096 15.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 ETS85487.1 - 0.0066 15.6 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 ETS85487.1 - 0.014 15.5 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ETS85487.1 - 0.021 15.0 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ETS85487.1 - 0.043 13.4 0.0 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ETS85487.1 - 0.06 13.9 0.0 0.17 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ETS85487.1 - 0.067 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ETS85487.1 - 0.097 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 ETS85487.1 - 0.11 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 ETS85487.1 - 0.2 11.3 0.0 0.43 10.3 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.6 ETS85487.1 - 0.6 9.8 5.0 1.2 8.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain Ribosomal_S17 PF00366.20 ETS85488.1 - 2.8e-16 59.4 1.5 5.5e-16 58.4 1.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 MBOAT_2 PF13813.6 ETS85488.1 - 0.062 13.6 0.2 0.097 13.0 0.2 1.5 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family TAtT PF16811.5 ETS85488.1 - 0.066 12.5 3.5 0.11 11.8 3.5 1.2 1 0 0 1 1 1 0 TRAP transporter T-component adh_short PF00106.25 ETS85489.1 - 3.4e-20 72.3 1.2 7.4e-19 68.0 0.9 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ETS85489.1 - 1e-10 41.8 0.7 1.5e-10 41.3 0.7 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ETS85489.1 - 1.3e-10 41.3 0.2 2.5e-10 40.3 0.2 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase EMG1 PF03587.14 ETS85490.1 - 1.4e-79 266.3 0.0 1.6e-79 266.1 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase PH PF00169.29 ETS85492.1 - 0.00014 22.3 0.0 0.00027 21.4 0.0 1.5 1 0 0 1 1 1 1 PH domain WEMBL PF05701.11 ETS85492.1 - 0.13 10.9 1.1 0.19 10.4 1.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Macoilin PF09726.9 ETS85492.1 - 4.1 5.8 6.9 8.3 4.8 6.9 1.5 1 0 0 1 1 1 0 Macoilin family DUF2013 PF09431.10 ETS85493.1 - 4e-51 172.8 2.2 7.3e-51 172.0 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Topo-VIb_trans PF09239.11 ETS85494.1 - 0.048 13.5 0.1 0.2 11.5 0.1 1.9 2 0 0 2 2 2 0 Topoisomerase VI B subunit, transducer NOC3p PF07540.11 ETS85494.1 - 0.12 12.8 0.0 0.44 11.0 0.0 2.0 2 0 0 2 2 2 0 Nucleolar complex-associated protein Xpo1 PF08389.12 ETS85495.1 - 4.3e-08 33.3 0.3 7.5e-06 26.1 0.0 3.4 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 ETS85495.1 - 2.2e-07 30.7 3.3 2.6e-07 30.5 0.2 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Con-6 PF10346.9 ETS85495.1 - 0.031 14.3 0.1 0.073 13.1 0.1 1.6 1 0 0 1 1 1 0 Conidiation protein 6 PLN_propep PF16485.5 ETS85495.1 - 0.052 13.3 1.3 0.082 12.6 0.2 1.9 2 0 0 2 2 2 0 Protealysin propeptide WD40 PF00400.32 ETS85496.1 - 0.0052 17.6 1.0 6.4 7.8 0.0 4.2 3 1 0 3 3 3 2 WD domain, G-beta repeat DUF1917 PF08939.10 ETS85497.1 - 8.3e-81 271.7 0.0 1e-80 271.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) TrmB PF01978.19 ETS85497.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Acetyltransf_1 PF00583.25 ETS85498.1 - 3.3e-20 72.5 0.0 4.2e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS85498.1 - 9.9e-11 41.7 0.0 1.4e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS85498.1 - 2.5e-10 40.6 0.0 3.5e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS85498.1 - 6.2e-10 38.9 0.0 8.5e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ETS85498.1 - 3.6e-07 30.9 0.0 4.4e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETS85498.1 - 1.3e-06 28.5 0.2 2.3e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ETS85498.1 - 1.9e-06 27.6 0.0 2.3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ETS85498.1 - 0.00076 19.6 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 ETS85498.1 - 0.035 13.7 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_18 PF18014.1 ETS85498.1 - 0.097 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LCAT PF02450.15 ETS85499.1 - 4.7e-100 335.5 0.1 5.6e-100 335.3 0.1 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 ETS85499.1 - 0.054 14.1 0.1 0.098 13.2 0.1 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family THUMP PF02926.17 ETS85500.1 - 8.5e-11 42.1 0.2 2.5e-10 40.6 0.2 1.7 1 1 0 1 1 1 1 THUMP domain MFS_1 PF07690.16 ETS85502.1 - 1.1e-43 149.6 55.2 3.2e-43 148.0 53.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily COG6 PF06419.11 ETS85503.1 - 1.6e-215 717.0 9.1 1.9e-215 716.9 9.1 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Sec8_exocyst PF04048.14 ETS85503.1 - 0.0012 18.7 1.8 0.043 13.7 1.1 2.8 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 ETS85503.1 - 0.0016 18.6 1.1 0.0073 16.4 1.1 2.1 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF1043 PF06295.12 ETS85503.1 - 0.012 15.6 1.3 0.012 15.6 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Spore_IV_A PF09547.10 ETS85503.1 - 0.035 13.0 0.4 0.06 12.3 0.4 1.3 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) RmuC PF02646.16 ETS85503.1 - 0.11 11.6 3.9 0.082 12.0 1.4 2.1 2 0 0 2 2 2 0 RmuC family DUF948 PF06103.11 ETS85503.1 - 0.31 11.3 2.7 1.7 9.0 1.6 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec34 PF04136.15 ETS85503.1 - 0.59 10.0 8.2 1.1 9.2 1.5 3.1 2 1 0 3 3 3 0 Sec34-like family APG9 PF04109.16 ETS85504.1 - 2.2e-186 620.6 10.9 2.6e-186 620.3 10.9 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Gar1 PF04410.14 ETS85505.1 - 2.5e-37 128.0 0.0 3.2e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.25 ETS85506.1 - 1.3e-32 113.2 0.0 3e-30 105.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ETS85506.1 - 2.5e-19 69.2 0.1 5.7e-19 68.1 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 ETS85506.1 - 4.1e-11 42.8 0.0 8.4e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 ETS85506.1 - 1e-10 41.5 0.0 2.4e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 TGS domain CDP-OH_P_transf PF01066.21 ETS85507.1 - 1.8e-12 47.9 0.7 3.4e-12 47.0 0.1 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Metallopep PF12044.8 ETS85508.1 - 2.1e-171 570.3 0.0 2.6e-171 570.0 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 ETS85508.1 - 0.00046 20.1 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_5 PF13688.6 ETS85508.1 - 0.0023 18.1 0.2 0.0047 17.1 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 ETS85508.1 - 0.015 15.2 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Asp2 PF16929.5 ETS85508.1 - 0.2 10.6 0.0 0.31 10.0 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Whi5 PF08528.11 ETS85509.1 - 4.2e-07 29.4 0.0 9.2e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 Whi5 like SKG6 PF08693.10 ETS85510.1 - 0.0053 16.1 3.7 0.037 13.4 3.7 2.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SNARE_assoc PF09335.11 ETS85510.1 - 0.084 13.4 1.0 0.19 12.2 1.0 1.5 1 0 0 1 1 1 0 SNARE associated Golgi protein FAM76 PF16046.5 ETS85510.1 - 0.12 11.7 0.3 0.3 10.4 0.3 1.5 1 0 0 1 1 1 0 FAM76 protein Phage_holin_2_4 PF16082.5 ETS85510.1 - 0.71 9.6 2.8 3 7.7 2.8 2.1 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Sec10 PF07393.11 ETS85510.1 - 6.9 5.0 6.0 14 3.9 6.0 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec10 Amnionless PF14828.6 ETS85510.1 - 9.9 4.9 6.7 0.22 10.3 0.1 1.5 2 0 0 2 2 2 0 Amnionless FAM176 PF14851.6 ETS85511.1 - 0.38 10.4 5.2 0.27 10.9 0.4 2.4 2 0 0 2 2 2 0 FAM176 family Cytomega_UL84 PF06284.11 ETS85511.1 - 1.3 7.4 4.5 2.3 6.6 4.5 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Peptidase_C14 PF00656.22 ETS85512.1 - 5.8e-62 209.9 0.1 7.8e-62 209.4 0.1 1.1 1 0 0 1 1 1 1 Caspase domain Cnn_1N PF07989.11 ETS85513.1 - 6.3e-26 90.3 4.0 6.3e-26 90.3 4.0 16.1 6 4 9 16 16 14 2 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 ETS85513.1 - 1.3e-24 86.6 4.6 1.3e-24 86.6 4.6 5.1 6 0 0 6 6 5 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein MscS_porin PF12795.7 ETS85513.1 - 9.1e-07 28.7 199.6 0.0012 18.4 31.0 9.3 1 1 6 8 8 8 4 Mechanosensitive ion channel porin domain Lebercilin PF15619.6 ETS85513.1 - 0.00023 20.9 42.4 0.00067 19.4 29.6 12.4 4 2 6 11 11 9 2 Ciliary protein causing Leber congenital amaurosis disease CENP-F_leu_zip PF10473.9 ETS85513.1 - 0.00034 20.6 29.4 0.00034 20.6 29.4 11.5 1 1 8 10 10 10 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.11 ETS85513.1 - 0.00069 18.6 41.1 0.00069 18.6 41.1 7.1 2 1 3 6 6 4 2 Calcium binding and coiled-coil domain (CALCOCO1) like TPR_MLP1_2 PF07926.12 ETS85513.1 - 0.00091 19.3 22.5 0.00091 19.3 22.5 13.7 6 3 8 14 14 14 4 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 ETS85513.1 - 0.0016 17.4 199.3 0.0022 16.9 16.6 9.8 2 1 8 10 10 10 5 Spc7 kinetochore protein KASH_CCD PF14662.6 ETS85513.1 - 0.0019 18.0 24.4 0.0019 18.0 24.4 9.8 3 2 6 10 10 10 2 Coiled-coil region of CCDC155 or KASH FlxA PF14282.6 ETS85513.1 - 0.003 17.5 13.2 0.003 17.5 13.2 12.2 4 4 9 13 13 12 4 FlxA-like protein Img2 PF05046.14 ETS85513.1 - 0.23 11.8 5.2 7.6 6.9 0.4 4.1 3 0 0 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) Fez1 PF06818.15 ETS85513.1 - 0.31 11.5 200.7 0.36 11.3 24.8 9.6 1 1 6 7 7 5 0 Fez1 DUF4634 PF15465.6 ETS85513.1 - 0.34 11.2 7.3 1.1 9.6 0.4 4.0 4 0 0 4 4 3 0 Domain of unknown function (DUF4634) GAS PF13851.6 ETS85513.1 - 0.51 9.7 187.6 0.07 12.5 25.1 10.6 3 3 7 10 10 10 0 Growth-arrest specific micro-tubule binding RVT_N PF13655.6 ETS85513.1 - 0.87 9.9 6.5 5 7.5 0.1 4.7 4 0 0 4 4 4 0 N-terminal domain of reverse transcriptase ADIP PF11559.8 ETS85513.1 - 4.7 7.3 187.2 0.011 15.8 5.4 13.3 4 3 8 14 14 14 0 Afadin- and alpha -actinin-Binding HMMR_N PF15905.5 ETS85513.1 - 6.4 6.1 185.0 0.0086 15.6 31.2 9.0 2 1 4 7 7 7 0 Hyaluronan mediated motility receptor N-terminal Leu_zip PF15294.6 ETS85513.1 - 9.1 5.7 157.8 0.054 13.0 33.5 8.7 1 1 6 8 8 8 0 Leucine zipper YccV-like PF08755.11 ETS85514.1 - 1.1e-14 54.7 0.0 2.3e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 ETS85514.1 - 4.8e-14 52.2 0.0 1e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 ETS85514.1 - 3e-10 39.8 0.2 8.2e-10 38.4 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS85514.1 - 1.5e-06 27.9 1.4 3.2e-06 26.9 0.0 2.3 3 0 0 3 3 3 1 F-box domain Elongin_A PF06881.11 ETS85514.1 - 0.0056 17.2 0.1 0.011 16.2 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A TPP_enzyme_N PF02776.18 ETS85515.1 - 6.8e-32 110.4 0.1 1.3e-31 109.5 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ETS85515.1 - 1.7e-23 82.8 0.0 4.2e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ETS85515.1 - 4.9e-15 55.6 0.0 1.5e-13 50.8 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain FAA_hydrolase PF01557.18 ETS85516.1 - 1.3e-43 149.3 0.0 1.6e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Peptidase_C12 PF01088.21 ETS85517.1 - 1.8e-55 188.0 0.0 4e-55 186.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 ETS85517.1 - 0.00091 19.1 0.1 0.00091 19.1 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases DUF1989 PF09347.10 ETS85519.1 - 2.4e-61 206.2 0.0 3e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) CoA_trans PF01144.23 ETS85520.1 - 3.5e-98 327.3 1.3 4.7e-61 206.0 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Nrap_D4 PF17405.2 ETS85521.1 - 1.9e-54 184.2 0.0 3.3e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 ETS85521.1 - 2.4e-52 176.9 0.3 4.7e-52 176.0 0.3 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 ETS85521.1 - 1.3e-45 154.8 0.4 3.6e-42 143.7 0.1 2.4 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 ETS85521.1 - 1.2e-41 142.3 0.6 2.1e-41 141.5 0.6 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 ETS85521.1 - 1.3e-41 142.4 0.1 6e-41 140.2 0.0 2.1 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap_D6 PF17407.2 ETS85521.1 - 3.4e-28 98.5 0.0 1.6e-27 96.4 0.0 2.2 3 0 0 3 3 3 1 Nrap protein domain 6 SRP72 PF08492.12 ETS85521.1 - 0.025 15.0 0.0 0.57 10.7 0.0 2.5 2 0 0 2 2 2 0 SRP72 RNA-binding domain 3HCDH_RFF PF18321.1 ETS85521.1 - 0.1 13.0 0.0 0.35 11.4 0.0 1.9 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Evr1_Alr PF04777.13 ETS85522.1 - 3.6e-30 104.4 0.8 3.6e-30 104.4 0.8 1.6 2 0 0 2 2 2 1 Erv1 / Alr family HoxA13_N PF12284.8 ETS85522.1 - 1.3 9.6 7.7 0.82 10.3 4.4 2.2 1 1 1 2 2 2 0 Hox protein A13 N terminal HEM4 PF02602.15 ETS85523.1 - 3.8e-39 134.4 0.0 5.2e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Fungal_trans_2 PF11951.8 ETS85524.1 - 2.3e-08 33.3 0.2 5.9e-08 31.9 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS85524.1 - 3.1e-06 27.2 12.3 3.1e-06 27.2 12.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec23_trunk PF04811.15 ETS85526.1 - 6.7e-71 238.7 0.0 1.1e-70 238.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 ETS85526.1 - 6.8e-23 80.5 0.1 3.7e-22 78.1 0.0 2.3 2 1 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 ETS85526.1 - 3.5e-18 66.1 0.1 7.2e-18 65.1 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 ETS85526.1 - 1.3e-16 60.3 4.6 2.3e-16 59.5 4.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ETS85526.1 - 4.1e-10 39.4 0.0 8.9e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 ETS85526.1 - 0.031 13.6 0.2 0.1 12.0 0.2 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Atrophin-1 PF03154.15 ETS85526.1 - 3.9 5.6 10.2 6 5.0 10.2 1.2 1 0 0 1 1 1 0 Atrophin-1 family Pkinase PF00069.25 ETS85527.1 - 6.4e-68 229.0 0.0 8.5e-68 228.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS85527.1 - 5.2e-32 111.2 0.0 6.7e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ETS85527.1 - 0.00029 20.3 0.3 0.00048 19.5 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ETS85527.1 - 0.0012 17.9 0.2 0.0019 17.2 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ETS85527.1 - 0.0085 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ETS85527.1 - 0.025 14.5 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ETS85527.1 - 0.053 12.6 0.1 0.081 12.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gag_p6 PF08705.11 ETS85527.1 - 0.097 12.9 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 S_100 PF01023.19 ETS85527.1 - 0.13 12.0 0.2 0.38 10.5 0.2 1.8 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain adh_short_C2 PF13561.6 ETS85528.1 - 9.3e-13 48.3 0.0 6.8e-12 45.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS85528.1 - 8.2e-11 41.7 0.0 5.8e-10 39.0 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase TLD PF07534.16 ETS85529.1 - 1.8e-23 83.3 0.0 8.1e-12 45.5 0.0 2.3 2 0 0 2 2 2 2 TLD DNA_pol3_finger PF17657.1 ETS85530.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit finger domain DIOX_N PF14226.6 ETS85531.1 - 6.4e-22 78.5 0.0 8.6e-21 74.9 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS85531.1 - 2.5e-11 43.9 0.0 4.9e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 ETS85532.1 - 9.9e-19 67.5 52.3 7e-13 48.2 30.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 7TM_GPCR_Srh PF10318.9 ETS85532.1 - 0.015 14.4 0.7 0.015 14.4 0.7 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh EI24 PF07264.11 ETS85534.1 - 1.4e-12 48.2 15.0 2.1e-12 47.6 15.0 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) YqzE PF14038.6 ETS85534.1 - 0.12 12.4 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 YqzE-like protein ARD PF03079.14 ETS85535.1 - 0.15 12.2 1.7 21 5.3 0.0 3.1 2 1 1 3 3 3 0 ARD/ARD' family Pkinase PF00069.25 ETS85536.1 - 1.2e-16 60.9 0.0 4.6e-09 36.0 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS85536.1 - 2.6e-06 26.9 0.0 0.012 14.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF3716 PF12511.8 ETS85537.1 - 1.1 9.3 7.0 0.31 11.1 3.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) NUDIX PF00293.28 ETS85538.1 - 4.6e-17 62.3 0.1 6e-17 61.9 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Met_10 PF02475.16 ETS85539.1 - 2.4e-06 27.5 0.0 2.3e-05 24.3 0.0 2.0 1 1 1 2 2 2 1 Met-10+ like-protein RhoGAP PF00620.27 ETS85539.1 - 0.0094 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain EF-hand_6 PF13405.6 ETS85540.1 - 3.8e-09 35.7 0.5 0.00032 20.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 ETS85540.1 - 5.2e-07 30.0 0.2 1.2e-06 28.9 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 ETS85540.1 - 1.4e-05 24.3 1.3 5e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 ETS85540.1 - 0.002 17.5 0.0 0.0048 16.3 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 ETS85540.1 - 0.0026 17.6 0.9 0.0067 16.3 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair ORC6 PF05460.13 ETS85541.1 - 1.5e-35 123.1 6.2 7e-35 120.9 6.2 1.8 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) OPT PF03169.15 ETS85543.1 - 1.1e-129 434.0 45.5 1.2e-129 433.7 45.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein adh_short PF00106.25 ETS85544.1 - 1.7e-34 119.0 0.0 2.2e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS85544.1 - 4.2e-26 91.9 0.0 1e-25 90.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS85544.1 - 3e-13 50.1 0.0 4.4e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS85544.1 - 1.1e-05 24.7 0.0 1.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 ETS85544.1 - 0.0023 17.4 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 ETS85544.1 - 0.058 13.8 0.2 0.13 12.7 0.2 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 ETS85544.1 - 0.058 12.6 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS85546.1 - 7.9e-12 45.1 0.1 1.5e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS85546.1 - 0.00043 20.0 3.6 0.43 10.1 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS85546.1 - 0.00083 19.5 1.5 0.0026 17.9 1.5 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ETS85546.1 - 0.00097 19.6 1.4 0.00097 19.6 1.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS85546.1 - 0.0011 18.3 1.2 0.0035 16.6 0.4 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS85546.1 - 0.002 16.9 1.3 0.0026 16.5 0.6 1.5 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 ETS85546.1 - 0.0028 17.0 0.9 0.13 11.6 0.3 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 ETS85546.1 - 0.0035 16.8 0.1 0.0054 16.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS85546.1 - 0.01 15.0 1.7 0.023 13.8 1.7 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 ETS85546.1 - 0.098 11.9 0.5 0.48 9.6 0.1 1.9 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Spore_YtrH PF14034.6 ETS85546.1 - 0.3 11.3 1.3 2.9 8.1 0.4 2.6 3 0 0 3 3 3 0 Sporulation protein YtrH AlaDh_PNT_C PF01262.21 ETS85546.1 - 0.38 10.0 3.2 1.4 8.2 3.2 2.0 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 ETS85547.1 - 4.4e-52 177.9 0.0 6.9e-52 177.2 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ETS85547.1 - 1.4e-12 47.7 0.3 3.2e-12 46.5 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS85547.1 - 5.1e-06 26.3 0.0 8.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ETS85547.1 - 4.7e-05 22.7 0.2 8e-05 22.0 0.2 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 ETS85547.1 - 6.2e-05 22.3 0.2 0.00012 21.3 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 ETS85547.1 - 8.9e-05 21.9 0.3 0.00032 20.1 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS85547.1 - 0.00013 21.3 0.0 0.0037 16.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS85547.1 - 0.00022 20.1 0.2 0.0032 16.2 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 ETS85547.1 - 0.001 18.5 0.9 0.0016 17.9 0.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS85547.1 - 0.0016 17.8 0.1 0.004 16.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS85547.1 - 0.0064 17.0 0.2 0.013 16.0 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ETS85547.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 ETS85547.1 - 0.052 12.6 0.1 0.086 11.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 ETS85547.1 - 0.055 13.1 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA dsrm PF00035.26 ETS85548.1 - 7.8e-05 23.3 0.0 0.00022 21.9 0.0 1.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 ETS85548.1 - 0.0043 17.3 0.0 0.0075 16.5 0.0 1.5 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 ABC_tran PF00005.27 ETS85549.1 - 4e-48 163.4 0.1 3.5e-26 92.3 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS85549.1 - 8.8e-39 133.8 25.0 1e-28 100.8 12.3 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ETS85549.1 - 1.6e-15 57.2 1.3 2.6e-05 23.8 0.7 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETS85549.1 - 8.5e-09 35.6 0.4 0.035 13.9 0.0 3.8 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ETS85549.1 - 6e-07 29.5 1.4 0.002 18.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ETS85549.1 - 4.4e-06 26.3 0.2 0.096 12.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 ETS85549.1 - 7.4e-06 25.9 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.6 ETS85549.1 - 4.6e-05 23.9 1.4 0.098 13.0 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 ETS85549.1 - 0.00015 22.2 0.1 0.2 12.1 0.0 3.7 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 ETS85549.1 - 0.00022 20.4 2.3 0.27 10.2 0.0 2.7 3 0 0 3 3 3 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 ETS85549.1 - 0.00025 21.1 0.6 0.67 10.1 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF815 PF05673.13 ETS85549.1 - 0.00044 19.5 0.1 0.17 11.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 ETS85549.1 - 0.00048 20.4 1.3 1.3 9.3 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 ETS85549.1 - 0.00065 19.3 0.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_23 PF13476.6 ETS85549.1 - 0.0013 19.3 0.1 2.3 8.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 ETS85549.1 - 0.0017 18.5 1.5 0.34 10.9 0.0 2.8 3 0 0 3 3 2 1 Dynamin family KAP_NTPase PF07693.14 ETS85549.1 - 0.0024 17.2 0.0 0.67 9.1 0.0 2.3 2 0 0 2 2 2 1 KAP family P-loop domain NB-ARC PF00931.22 ETS85549.1 - 0.0079 15.4 0.1 4.1 6.5 0.0 3.4 3 0 0 3 3 3 1 NB-ARC domain TrwB_AAD_bind PF10412.9 ETS85549.1 - 0.013 14.4 0.1 4.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MeaB PF03308.16 ETS85549.1 - 0.031 13.2 0.4 0.54 9.2 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SbcCD_C PF13558.6 ETS85549.1 - 0.032 14.5 0.3 20 5.5 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 ETS85549.1 - 0.045 14.2 0.1 9.6 6.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.12 ETS85549.1 - 0.053 12.8 0.1 8.1 5.7 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 ETS85549.1 - 0.064 12.8 1.8 6 6.4 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 ETS85549.1 - 0.082 12.8 0.3 12 5.7 0.0 3.0 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 ETS85549.1 - 0.091 12.5 0.2 17 5.1 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein NACHT PF05729.12 ETS85549.1 - 0.094 12.6 1.1 15 5.5 0.1 2.9 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 ETS85549.1 - 0.1 12.3 0.0 25 4.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 ETS85549.1 - 0.11 11.8 0.2 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family TsaE PF02367.17 ETS85549.1 - 0.13 12.2 0.4 2.1 8.4 0.0 2.7 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Adeno_IVa2 PF02456.15 ETS85549.1 - 0.15 10.8 0.8 4.8 5.9 0.1 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_18 PF13238.6 ETS85549.1 - 0.16 12.5 0.2 7.1 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ETS85549.1 - 0.17 12.0 0.1 15 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 ETS85549.1 - 0.24 11.4 1.6 0.28 11.2 0.1 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain Rad17 PF03215.15 ETS85549.1 - 0.25 11.3 0.7 12 5.8 0.1 3.0 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_5 PF07728.14 ETS85549.1 - 0.27 11.2 2.3 19 5.3 0.2 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Roc PF08477.13 ETS85549.1 - 0.33 11.2 0.8 16 5.7 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase LCCL PF03815.19 ETS85555.1 - 1.6e-19 69.8 0.0 3e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 LCCL domain LrgA PF03788.14 ETS85555.1 - 0.99 9.4 6.6 0.24 11.4 0.2 2.8 3 0 0 3 3 3 0 LrgA family Dioxygenase_C PF00775.21 ETS85556.1 - 3.3e-11 42.9 0.1 7.7e-11 41.8 0.1 1.6 1 1 0 1 1 1 1 Dioxygenase Methyltransf_31 PF13847.6 ETS85558.1 - 1.3e-27 96.5 0.0 2e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS85558.1 - 4.6e-24 84.9 0.0 7.5e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS85558.1 - 2.9e-23 82.4 0.0 6.5e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS85558.1 - 1.4e-17 63.8 0.0 2.2e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ETS85558.1 - 7e-15 55.6 0.0 1.2e-14 54.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS85558.1 - 4.6e-10 39.6 0.0 6e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS85558.1 - 2.6e-07 30.4 0.0 4.3e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 ETS85558.1 - 1e-06 28.4 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.12 ETS85558.1 - 3e-06 26.9 0.0 4.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 ETS85558.1 - 1.4e-05 24.9 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 ETS85558.1 - 2.2e-05 23.9 0.0 3.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_32 PF13679.6 ETS85558.1 - 0.00012 22.1 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ETS85558.1 - 0.0002 21.3 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ETS85558.1 - 0.0004 19.9 0.0 0.0006 19.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 ETS85558.1 - 0.0011 18.1 0.0 0.0016 17.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.14 ETS85558.1 - 0.0013 18.2 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB DUF938 PF06080.12 ETS85558.1 - 0.0019 18.0 0.0 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) FtsJ PF01728.19 ETS85558.1 - 0.0023 18.0 0.0 0.0031 17.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 ETS85558.1 - 0.0026 18.8 0.1 0.007 17.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain DREV PF05219.12 ETS85558.1 - 0.0048 16.0 0.0 0.0073 15.4 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase GCD14 PF08704.10 ETS85558.1 - 0.0049 16.6 0.0 0.0071 16.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit GidB PF02527.15 ETS85558.1 - 0.01 15.2 0.0 0.03 13.6 0.0 1.8 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G CheR PF01739.18 ETS85558.1 - 0.017 14.6 0.0 5.7 6.4 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_9 PF08003.11 ETS85558.1 - 0.051 12.5 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 ETS85558.1 - 0.053 13.2 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_29 PF03141.16 ETS85558.1 - 0.098 11.2 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Cupin_5 PF06172.11 ETS85559.1 - 2.6e-40 137.8 0.0 3.5e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) TetR_C_22 PF17928.1 ETS85559.1 - 0.043 14.1 0.0 0.12 12.7 0.0 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Holin_SPP1 PF04688.13 ETS85561.1 - 0.033 14.3 2.1 0.04 14.1 0.4 1.9 2 0 0 2 2 2 0 SPP1 phage holin GFO_IDH_MocA PF01408.22 ETS85562.1 - 3.2e-18 66.7 0.0 5.5e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF1145 PF06611.12 ETS85563.1 - 0.06 13.3 0.9 0.15 12.0 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1145) p450 PF00067.22 ETS85564.1 - 3.5e-71 240.4 0.0 4e-71 240.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Clr5 PF14420.6 ETS85565.1 - 2.5e-17 62.8 1.6 7.1e-17 61.4 1.6 1.8 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 ETS85565.1 - 0.013 15.8 1.6 0.78 10.1 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 ETS85567.1 - 2.1e-05 25.2 0.2 5.9e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ETS85567.1 - 0.00026 20.6 0.0 0.00048 19.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ETS85567.1 - 0.0015 18.2 0.3 0.012 15.3 0.3 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 ETS85567.1 - 0.002 16.8 0.0 0.0083 14.8 0.0 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) LIP PF03583.14 ETS85567.1 - 0.0072 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Secretory lipase DUF1100 PF06500.11 ETS85567.1 - 0.028 13.2 0.0 0.057 12.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.18 ETS85567.1 - 0.065 12.8 2.0 0.7 9.4 0.0 3.2 2 1 2 4 4 4 0 Dienelactone hydrolase family BAAT_C PF08840.11 ETS85567.1 - 0.089 12.7 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 ETS85567.1 - 0.096 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 UPF0227 PF05728.12 ETS85567.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Peptidase_S15 PF02129.18 ETS85567.1 - 0.18 11.4 0.2 1.6 8.2 0.1 2.7 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF676 PF05057.14 ETS85567.1 - 0.22 11.0 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) CBM_20 PF00686.19 ETS85569.1 - 3.1e-32 110.3 0.1 7e-32 109.2 0.1 1.6 1 0 0 1 1 1 1 Starch binding domain LPMO_10 PF03067.15 ETS85569.1 - 2.5e-13 51.1 1.8 4.8e-13 50.2 1.8 1.5 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Sporozoite_P67 PF05642.11 ETS85569.1 - 0.0073 14.5 6.5 0.0092 14.1 6.5 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Glyco_hydro_61 PF03443.14 ETS85569.1 - 0.062 13.2 5.8 0.22 11.4 0.4 2.9 2 1 1 3 3 3 0 Glycosyl hydrolase family 61 GFA PF04828.14 ETS85571.1 - 2.2e-18 66.4 0.1 3.3e-18 65.8 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme adh_short PF00106.25 ETS85574.1 - 7.3e-18 64.7 0.0 3.4e-16 59.3 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS85574.1 - 6.2e-08 32.5 0.1 1.2e-07 31.5 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS85574.1 - 7.9e-08 32.4 0.1 1.3e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_4 PF02390.17 ETS85574.1 - 0.18 11.3 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase SecY PF00344.20 ETS85575.1 - 5.3e-71 239.4 8.0 6.9e-71 239.0 8.0 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 ETS85575.1 - 1.1e-17 63.6 0.3 3.2e-17 62.1 0.3 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p IPPT PF01715.17 ETS85576.1 - 3.2e-62 210.3 0.1 3.2e-62 210.3 0.1 1.4 2 0 0 2 2 2 1 IPP transferase zf-met PF12874.7 ETS85576.1 - 4.3e-06 26.9 0.3 9.4e-06 25.9 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_18 PF13238.6 ETS85576.1 - 1.9e-05 25.2 0.0 0.39 11.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain zf-C2H2_jaz PF12171.8 ETS85576.1 - 0.00019 21.6 0.3 0.00044 20.4 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding IPT PF01745.16 ETS85576.1 - 0.00073 19.0 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Isopentenyl transferase CTU2 PF10288.9 ETS85576.1 - 0.0092 16.2 2.4 0.0092 16.2 2.4 1.8 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 AAA_33 PF13671.6 ETS85576.1 - 0.01 16.0 0.3 0.59 10.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 ETS85576.1 - 0.032 14.0 0.2 0.073 12.8 0.0 1.8 2 1 0 2 2 2 0 Cytidylate kinase PhoH PF02562.16 ETS85576.1 - 0.092 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein adh_short PF00106.25 ETS85577.1 - 4e-33 114.5 0.0 4.2e-32 111.2 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS85577.1 - 1.6e-20 73.7 0.0 1.7e-10 40.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Pyr_redox_3 PF13738.6 ETS85578.1 - 1.4e-18 67.2 0.0 1.1e-15 57.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS85578.1 - 1.2e-16 60.8 0.0 9.2e-14 51.4 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ETS85578.1 - 1.9e-14 53.0 0.3 5.5e-12 44.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ETS85578.1 - 2.7e-09 36.6 0.1 1e-07 31.4 0.1 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 ETS85578.1 - 2.9e-06 26.8 0.0 0.0001 21.7 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 ETS85578.1 - 3.9e-05 23.8 0.0 0.00025 21.2 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 ETS85578.1 - 7e-05 22.3 0.1 0.014 14.8 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 ETS85578.1 - 9.4e-05 22.9 0.1 0.076 13.6 0.0 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 ETS85578.1 - 0.0046 16.9 0.1 0.2 11.5 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ETS85578.1 - 0.0086 16.1 0.0 3.8 7.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 ETS85578.1 - 0.013 14.6 0.3 0.028 13.5 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 ETS85578.1 - 0.028 13.5 0.1 0.84 8.6 0.0 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A ApbA PF02558.16 ETS85578.1 - 0.028 14.0 0.0 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 ETS85578.1 - 0.033 12.9 0.2 0.13 10.9 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 ETS85578.1 - 0.04 13.2 0.0 0.47 9.7 0.0 2.1 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 ETS85578.1 - 0.13 12.7 0.0 5.2 7.6 0.0 2.6 3 0 0 3 3 2 0 Putative NAD(P)-binding IlvN PF07991.12 ETS85578.1 - 0.17 11.4 0.2 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GMC_oxred_N PF00732.19 ETS85579.1 - 1.1e-60 205.5 0.0 1.4e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS85579.1 - 1.5e-29 103.4 0.0 4.6e-29 101.8 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase Thi4 PF01946.17 ETS85579.1 - 0.00032 20.0 0.1 0.00067 19.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 ETS85579.1 - 0.0004 19.6 0.0 0.00074 18.7 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ETS85579.1 - 0.00043 19.5 0.1 0.37 9.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS85579.1 - 0.0039 17.4 0.0 0.012 15.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ETS85579.1 - 0.005 15.6 0.0 0.32 9.7 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 ETS85579.1 - 0.0095 15.2 0.0 0.049 12.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS85579.1 - 0.038 13.2 0.0 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS85579.1 - 0.097 12.2 0.1 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.18 ETS85579.1 - 0.11 12.7 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Elongin_A PF06881.11 ETS85580.1 - 0.019 15.5 0.8 6.2 7.4 0.1 2.1 1 1 1 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DnaJ_CXXCXGXG PF00684.19 ETS85580.1 - 0.022 15.1 1.2 0.031 14.7 1.2 1.2 1 0 0 1 1 1 0 DnaJ central domain SCIFF PF13165.6 ETS85580.1 - 0.15 12.0 2.2 9.8 6.2 0.2 2.2 2 0 0 2 2 2 0 Six-cysteine peptide SCIFF p450 PF00067.22 ETS85581.1 - 4.2e-64 217.0 0.0 5e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PhyH PF05721.13 ETS85582.1 - 1.5e-16 61.3 0.0 2.4e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Exo_endo_phos PF03372.23 ETS85583.1 - 1.5e-11 44.3 0.9 2.7e-11 43.5 0.9 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lipase_GDSL PF00657.22 ETS85584.1 - 6.1e-06 26.4 0.5 8.9e-06 25.8 0.5 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ETS85584.1 - 0.0054 17.1 2.6 0.018 15.4 2.6 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.16 ETS85585.1 - 1.5e-24 86.6 31.4 1.5e-24 86.6 31.4 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS85585.1 - 1.8e-06 27.1 12.7 1.8e-06 27.1 12.7 3.2 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.6 ETS85585.1 - 1.5 7.3 30.2 0.064 11.8 2.6 3.3 2 2 1 3 3 3 0 MFS/sugar transport protein PAT1 PF09770.9 ETS85586.1 - 0.081 11.2 0.4 0.086 11.1 0.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AbiEii PF08843.11 ETS85587.1 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.4 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system MdcG PF10620.9 ETS85587.1 - 0.01 15.6 0.1 0.022 14.5 0.0 1.5 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG Amidase PF01425.21 ETS85588.1 - 7.4e-81 272.4 0.0 1.3e-80 271.6 0.0 1.4 1 1 0 1 1 1 1 Amidase Epimerase PF01370.21 ETS85589.1 - 7.7e-13 48.5 0.0 1.2e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS85589.1 - 1.1e-05 25.4 6.2 0.00023 21.1 6.2 2.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS85589.1 - 2e-05 24.3 1.5 0.0081 15.7 0.9 2.1 2 0 0 2 2 2 2 NmrA-like family 3Beta_HSD PF01073.19 ETS85589.1 - 3.7e-05 22.9 0.0 7.4e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CbiJ PF02571.14 ETS85589.1 - 8.4e-05 22.1 0.5 0.00014 21.4 0.5 1.3 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK GDP_Man_Dehyd PF16363.5 ETS85589.1 - 0.0001 21.9 0.1 0.0011 18.4 0.1 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ETS85589.1 - 0.00012 21.3 0.3 0.00022 20.4 0.3 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 ETS85589.1 - 0.0024 17.8 0.8 0.023 14.6 0.3 2.2 2 0 0 2 2 2 1 KR domain F420_oxidored PF03807.17 ETS85589.1 - 0.017 15.7 0.1 0.04 14.5 0.1 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.26 ETS85589.1 - 0.081 12.9 1.9 8.2 6.4 0.5 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase NAD_Gly3P_dh_N PF01210.23 ETS85589.1 - 0.091 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.19 ETS85590.1 - 2.4e-15 56.7 1.1 4.3e-15 55.8 1.1 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS85590.1 - 1.8e-05 24.5 3.7 3.3e-05 23.7 1.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS85590.1 - 0.00011 21.6 0.2 0.00097 18.4 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS85590.1 - 0.00069 20.1 2.6 0.0014 19.1 0.6 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ETS85590.1 - 0.0014 17.7 0.0 0.022 13.8 0.0 2.1 1 1 0 1 1 1 1 Squalene epoxidase 3HCDH_N PF02737.18 ETS85590.1 - 0.0018 18.2 1.8 0.0031 17.4 0.6 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 ETS85590.1 - 0.012 14.7 0.6 0.021 13.9 0.6 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ETS85590.1 - 0.015 15.6 0.4 0.034 14.4 0.4 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 ETS85590.1 - 0.02 14.2 0.7 0.042 13.1 0.7 1.7 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 ETS85590.1 - 0.04 13.2 0.1 0.09 12.0 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS85590.1 - 0.04 12.6 0.4 0.072 11.8 0.4 1.4 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 ETS85590.1 - 0.069 12.8 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA M20_dimer PF07687.14 ETS85590.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase dimerisation domain UDPG_MGDP_dh_N PF03721.14 ETS85590.1 - 0.13 11.8 0.3 0.27 10.8 0.3 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 ETS85590.1 - 0.14 11.5 0.0 0.34 10.2 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HET PF06985.11 ETS85591.1 - 4.5e-29 101.7 2.8 8.8e-29 100.7 2.8 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_1 PF00515.28 ETS85591.1 - 0.024 14.4 0.0 0.067 13.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 ETS85591.1 - 0.082 13.2 0.0 0.4 11.0 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Ank_2 PF12796.7 ETS85592.1 - 1.1e-14 54.7 0.1 0.00015 22.3 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS85592.1 - 1.4e-14 53.9 0.7 0.00033 20.9 0.1 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS85592.1 - 1.3e-12 48.0 2.3 0.00038 21.0 0.0 4.7 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS85592.1 - 1.9e-11 43.1 1.6 0.0034 17.7 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 ETS85592.1 - 9.6e-09 35.3 4.8 0.044 14.3 0.2 5.0 5 0 0 5 5 5 2 Ankyrin repeat DUF4129 PF13559.6 ETS85592.1 - 0.031 14.5 1.8 22 5.4 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4129) NACHT_N PF17100.5 ETS85593.1 - 7.4e-14 52.1 0.6 2.1e-13 50.7 0.6 1.7 1 1 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 ETS85593.1 - 2e-07 31.0 0.0 7.2e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS85593.1 - 3.2e-07 30.9 0.1 1.7e-06 28.5 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS85593.1 - 6.8e-06 26.4 0.0 4.3e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ETS85593.1 - 3.5e-05 24.2 1.9 0.00058 20.3 1.9 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_4 PF17864.1 ETS85593.1 - 0.0017 18.1 0.1 0.0065 16.2 0.0 2.0 2 0 0 2 2 2 1 RuvB AAA lid domain Goodbye PF17109.5 ETS85593.1 - 0.0078 16.7 1.1 1.6 9.2 0.1 3.0 2 1 0 3 3 3 1 fungal STAND N-terminal Goodbye domain NB-ARC PF00931.22 ETS85593.1 - 0.015 14.5 0.1 0.1 11.7 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 ETS85593.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Dyp_perox PF04261.12 ETS85594.1 - 0.00059 18.9 0.1 0.004 16.2 0.0 2.5 2 1 0 2 2 2 1 Dyp-type peroxidase family HET PF06985.11 ETS85595.1 - 7.4e-26 91.2 0.7 1.4e-25 90.3 0.7 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Amidase PF01425.21 ETS85596.1 - 2.1e-57 195.1 0.0 4.9e-55 187.3 0.0 2.1 2 0 0 2 2 2 2 Amidase UPF0730 PF15827.5 ETS85596.1 - 0.098 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 UPF0730 unknown protein family Cutinase PF01083.22 ETS85597.1 - 5.2e-34 117.7 0.4 6.3e-34 117.5 0.4 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 ETS85597.1 - 0.00024 20.7 0.1 0.00038 20.1 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain DUF3433 PF11915.8 ETS85598.1 - 3.3e-18 65.9 4.1 3.3e-18 65.9 4.1 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Ribonuc_L-PSP PF01042.21 ETS85600.1 - 5.1e-22 78.1 0.0 5.6e-22 78.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4386 PF14329.6 ETS85601.1 - 0.29 11.0 1.3 0.42 10.4 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) SnoaL_2 PF12680.7 ETS85602.1 - 0.0027 18.3 0.3 0.0063 17.1 0.1 1.6 1 1 1 2 2 2 1 SnoaL-like domain Pectate_lyase_3 PF12708.7 ETS85603.1 - 9e-90 300.2 3.0 2.1e-73 246.7 0.2 2.9 2 0 0 2 2 2 2 Pectate lyase superfamily protein LysM PF01476.20 ETS85603.1 - 7.7e-12 45.1 0.0 0.00018 21.5 0.0 3.8 3 0 0 3 3 3 3 LysM domain End_N_terminal PF12218.8 ETS85603.1 - 3.2e-06 26.7 3.3 0.042 13.5 0.2 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Glyco_hydro_18 PF00704.28 ETS85604.1 - 2.1e-70 237.9 0.2 3.1e-70 237.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ETS85604.1 - 4.5e-11 43.0 32.1 1.1e-09 38.6 8.3 5.9 6 0 0 6 6 6 2 Chitin recognition protein ISAV_HA PF06215.11 ETS85605.1 - 0.037 13.2 0.0 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Infectious salmon anaemia virus haemagglutinin Esterase PF00756.20 ETS85607.1 - 8.8e-09 35.4 0.0 1.2e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ETS85607.1 - 0.00051 19.6 0.0 0.0017 17.8 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family CLAG PF03805.13 ETS85607.1 - 0.26 8.8 0.0 0.35 8.4 0.0 1.1 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein Ank_2 PF12796.7 ETS85609.1 - 3.2e-50 168.6 1.3 8.5e-13 48.7 0.1 5.2 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) TPR_12 PF13424.6 ETS85609.1 - 7.2e-41 138.4 8.2 2.9e-11 43.5 1.2 5.5 4 1 0 5 5 4 4 Tetratricopeptide repeat Ank_5 PF13857.6 ETS85609.1 - 4.1e-38 128.9 5.1 2.5e-09 37.2 0.0 6.1 4 1 3 7 7 6 5 Ankyrin repeats (many copies) Ank PF00023.30 ETS85609.1 - 2e-37 126.0 0.0 0.00025 21.4 0.0 8.9 8 1 1 9 9 9 7 Ankyrin repeat TPR_10 PF13374.6 ETS85609.1 - 2e-37 126.0 14.4 1e-05 25.3 0.0 9.1 11 0 0 11 11 10 6 Tetratricopeptide repeat Ank_4 PF13637.6 ETS85609.1 - 2.4e-32 110.9 0.2 3.3e-06 27.5 0.0 6.1 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS85609.1 - 3.2e-27 91.6 0.3 8e-05 22.8 0.0 8.8 9 0 0 9 9 8 3 Ankyrin repeat Pkinase PF00069.25 ETS85609.1 - 3.7e-25 88.8 0.0 8.9e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS85609.1 - 1.9e-16 60.1 0.0 3.5e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_MalT PF17874.1 ETS85609.1 - 5.2e-11 42.5 4.8 1.4e-09 37.8 6.2 2.1 1 1 1 2 2 2 1 MalT-like TPR region TPR_19 PF14559.6 ETS85609.1 - 5.8e-07 29.9 7.9 0.26 11.8 0.1 4.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.14 ETS85609.1 - 8.2e-06 26.0 23.6 0.74 10.6 1.4 6.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 ETS85609.1 - 2.9e-05 23.9 19.2 2.6 8.4 0.6 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat Kdo PF06293.14 ETS85609.1 - 0.025 13.9 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_16 PF13432.6 ETS85609.1 - 0.031 14.9 14.3 0.82 10.4 0.1 4.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 ETS85609.1 - 0.038 14.0 12.5 11 6.3 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 ETS85609.1 - 0.047 14.0 5.0 67 3.9 0.1 5.5 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 ETS85609.1 - 0.23 11.3 14.9 13 5.8 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 ETS85609.1 - 0.64 10.4 8.1 25 5.4 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 ETS85609.1 - 6.6 6.8 6.0 13 5.9 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat COesterase PF00135.28 ETS85610.1 - 7e-85 285.8 0.0 8.9e-85 285.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS85610.1 - 0.005 16.7 0.0 0.005 16.7 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold SKG6 PF08693.10 ETS85611.1 - 6.9 6.2 9.1 0.2 11.1 1.6 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Peptidase_S10 PF00450.22 ETS85613.1 - 1.2e-75 255.5 0.0 1.7e-75 255.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 ETS85613.1 - 6.8e-06 25.5 0.0 0.034 13.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS85613.1 - 0.0014 18.3 0.1 0.22 11.2 0.0 2.7 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS85613.1 - 0.015 14.7 0.0 6.8 6.1 0.0 2.6 3 0 0 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 ETS85613.1 - 0.018 15.1 0.0 4.6 7.4 0.0 2.6 2 0 0 2 2 2 0 TAP-like protein PAN_4 PF14295.6 ETS85615.1 - 5.3e-06 26.3 17.9 0.0068 16.3 0.5 3.6 3 0 0 3 3 3 3 PAN domain PAN_2 PF08276.11 ETS85615.1 - 0.0014 18.7 3.3 3.2 7.9 0.1 3.5 3 0 0 3 3 3 3 PAN-like domain MANEC PF07502.14 ETS85615.1 - 0.068 13.4 14.2 0.55 10.5 3.2 3.6 3 0 0 3 3 3 0 MANEC domain PAN_1 PF00024.26 ETS85615.1 - 1.3 9.0 8.5 16 5.5 1.1 3.7 3 0 0 3 3 3 0 PAN domain DAO PF01266.24 ETS85616.1 - 1.2e-43 150.0 0.1 1.5e-43 149.8 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS85616.1 - 4.6e-06 26.1 0.0 0.06 12.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS85616.1 - 2.4e-05 24.5 0.0 7.8e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS85616.1 - 3.4e-05 23.9 0.2 0.12 12.3 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 ETS85616.1 - 0.00015 21.0 0.1 0.00025 20.3 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ETS85616.1 - 0.0022 18.5 0.0 0.0094 16.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS85616.1 - 0.0027 16.9 0.2 1.7 7.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 ETS85616.1 - 0.0047 15.7 0.0 0.038 12.7 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Glu_dehyd_C PF16912.5 ETS85616.1 - 0.0065 16.0 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Lycopene_cycl PF05834.12 ETS85616.1 - 0.032 13.3 0.2 0.93 8.5 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ETS85616.1 - 0.048 12.9 0.0 4.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS85616.1 - 0.078 12.2 0.1 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 ETS85616.1 - 0.15 12.4 0.0 0.52 10.6 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain FMO-like PF00743.19 ETS85617.1 - 1.3e-16 60.1 0.0 3.1e-16 58.9 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ETS85617.1 - 9.8e-12 44.9 0.3 5e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS85617.1 - 3e-10 39.8 0.0 7.1e-09 35.3 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS85617.1 - 3.5e-07 29.7 0.0 7.4e-05 22.0 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ETS85617.1 - 1.6e-05 24.7 0.2 0.0077 15.9 0.0 3.2 2 2 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS85617.1 - 0.00011 21.5 0.0 0.0044 16.3 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS85617.1 - 0.00015 21.8 0.0 0.012 15.6 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 ETS85617.1 - 0.0095 15.2 0.0 0.058 12.6 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.20 ETS85617.1 - 0.027 14.5 0.0 2.9 7.9 0.0 2.9 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 ETS85617.1 - 0.19 12.3 0.1 6.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ring_hydroxyl_A PF00848.19 ETS85618.1 - 4.9e-27 95.3 3.9 2.5e-23 83.2 3.9 2.5 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 ETS85618.1 - 3.2e-12 46.2 0.0 5.8e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Cupin_1 PF00190.22 ETS85619.1 - 2.6e-08 33.6 0.0 3.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 ETS85619.1 - 4.6e-07 29.5 0.1 8e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 ETS85619.1 - 0.012 15.3 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Cupin ARD PF03079.14 ETS85619.1 - 0.013 15.7 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family AraC_binding PF02311.19 ETS85619.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.5 1 1 0 1 1 1 0 AraC-like ligand binding domain ATG22 PF11700.8 ETS85620.1 - 5.7e-127 424.2 23.8 6.6e-127 424.0 23.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like IDO PF01231.18 ETS85621.1 - 1.9e-33 115.9 0.0 2.5e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Drf_FH3 PF06367.16 ETS85622.1 - 0.1 12.2 1.0 0.2 11.3 1.0 1.4 1 0 0 1 1 1 0 Diaphanous FH3 Domain Glyco_hydro_28 PF00295.17 ETS85625.1 - 1.4e-92 310.2 20.9 1.7e-92 309.9 20.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 CcmD PF04995.14 ETS85626.1 - 0.13 12.4 1.4 0.42 10.7 1.4 1.9 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) SET PF00856.28 ETS85627.1 - 2.8e-10 40.8 1.2 7.8e-09 36.1 0.1 3.3 2 1 0 2 2 2 1 SET domain Ribosomal_L14 PF00238.19 ETS85628.1 - 8.4e-46 155.0 3.6 9.9e-46 154.8 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RNA_POL_M_15KD PF02150.16 ETS85629.1 - 9.4e-11 41.4 1.7 2.2e-10 40.2 1.7 1.7 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit Nudix_N_2 PF14803.6 ETS85629.1 - 0.13 12.2 1.6 0.27 11.2 1.0 1.9 2 0 0 2 2 2 0 Nudix N-terminal GFA PF04828.14 ETS85629.1 - 0.17 12.2 4.4 2.7 8.4 0.1 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Rotamase PF00639.21 ETS85630.1 - 1.4e-22 80.5 0.0 2.1e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 ETS85630.1 - 1.5e-16 61.0 0.0 1.9e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 ETS85630.1 - 5.9e-08 32.7 1.2 6.9e-08 32.5 0.2 1.6 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 ETS85630.1 - 9.1e-05 23.3 0.0 0.00016 22.5 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW_1 PF18507.1 ETS85630.1 - 0.0007 19.2 0.2 0.0012 18.5 0.2 1.4 1 0 0 1 1 1 1 WW domain LrgB PF04172.16 ETS85631.1 - 6.5e-30 104.3 17.8 2.4e-22 79.5 2.0 2.7 3 0 0 3 3 3 2 LrgB-like family Microvir_lysis PF04517.12 ETS85631.1 - 0.84 9.6 3.7 0.53 10.2 1.4 1.9 2 0 0 2 2 2 0 Microvirus lysis protein (E), C terminus HAUS-augmin3 PF14932.6 ETS85632.1 - 0.0082 15.8 3.4 0.011 15.4 3.4 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 HalX PF08663.10 ETS85632.1 - 0.018 15.4 0.4 0.018 15.4 0.4 2.6 2 1 0 2 2 2 0 HalX domain Mt_ATP-synt_B PF05405.14 ETS85632.1 - 0.044 13.4 1.1 0.86 9.2 0.4 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) IL10 PF00726.17 ETS85632.1 - 0.092 12.2 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Interleukin 10 CLZ PF16526.5 ETS85632.1 - 0.19 12.1 2.3 2.1 8.8 0.7 2.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TipAS PF07739.13 ETS85632.1 - 0.24 12.0 5.9 0.27 11.8 1.7 2.1 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain Atg14 PF10186.9 ETS85632.1 - 0.45 9.6 4.1 0.59 9.2 4.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 ETS85632.1 - 0.49 10.5 9.3 0.68 10.0 8.6 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 ETS85632.1 - 0.72 8.7 6.3 0.69 8.7 5.5 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3138 PF11336.8 ETS85632.1 - 7.6 5.0 5.8 1.4 7.4 2.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Amidoligase_2 PF12224.8 ETS85634.1 - 8.8e-09 35.4 0.0 5.7e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Putative amidoligase enzyme Activator_LAG-3 PF11498.8 ETS85635.1 - 0.075 12.0 39.8 0.088 11.8 39.8 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 MDM10 PF12519.8 ETS85635.1 - 0.42 9.4 7.2 0.5 9.2 7.2 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF1168 PF06658.12 ETS85635.1 - 0.45 10.3 18.7 0.58 10.0 18.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) GET2 PF08690.10 ETS85635.1 - 0.97 9.1 12.9 1.1 8.8 12.9 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 eIF-3_zeta PF05091.12 ETS85635.1 - 1.2 8.0 15.1 1.3 7.9 15.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.14 ETS85635.1 - 1.4 8.8 10.9 1.5 8.7 10.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 ETS85635.1 - 8.4 5.0 15.5 10 4.8 15.5 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 ETS85635.1 - 8.9 4.5 14.0 10 4.2 14.0 1.0 1 0 0 1 1 1 0 CDC45-like protein NACHT_N PF17100.5 ETS85637.1 - 1.5e-21 77.3 1.5 3.2e-21 76.2 1.5 1.5 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 ETS85637.1 - 8.8e-13 48.7 0.2 2.9e-12 47.0 0.2 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS85637.1 - 5.2e-11 42.8 0.9 2.7e-07 31.0 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS85637.1 - 1.8e-10 40.8 0.8 0.00019 21.8 0.3 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 ETS85637.1 - 1.2e-09 37.5 1.3 0.056 14.0 0.1 4.6 4 0 0 4 4 3 3 Ankyrin repeat Ank_5 PF13857.6 ETS85637.1 - 1.2e-08 35.0 0.5 0.00015 22.0 0.0 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) NACHT PF05729.12 ETS85637.1 - 0.00023 21.1 0.2 0.00081 19.3 0.0 2.1 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 ETS85637.1 - 0.00045 20.6 2.2 0.00087 19.7 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 ETS85637.1 - 0.0044 17.4 0.3 1.5 9.3 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 ETS85637.1 - 0.017 14.3 0.1 2.2 7.5 0.1 2.4 1 1 1 2 2 2 0 KAP family P-loop domain DUF2408 PF10303.9 ETS85637.1 - 0.026 15.1 0.7 0.29 11.7 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) HRDC PF00570.23 ETS85638.1 - 5.4e-22 77.6 0.0 1.7e-16 60.0 0.0 2.5 2 0 0 2 2 2 2 HRDC domain DNA_pol_A_exo1 PF01612.20 ETS85638.1 - 1.1e-13 51.3 0.0 1.8e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HHH PF00633.23 ETS85638.1 - 0.0096 15.8 0.1 0.048 13.5 0.1 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF763 PF05559.11 ETS85638.1 - 0.056 12.6 0.1 0.7 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF763) HHH_3 PF12836.7 ETS85638.1 - 0.12 12.7 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif FMN_dh PF01070.18 ETS85639.1 - 6.2e-81 272.1 0.4 1.3e-46 159.3 0.1 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ETS85639.1 - 2.9e-05 23.4 0.0 0.018 14.2 0.0 2.2 2 0 0 2 2 2 2 Conserved region in glutamate synthase NMO PF03060.15 ETS85639.1 - 0.0028 17.1 0.4 0.016 14.6 0.0 2.0 2 0 0 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.25 ETS85639.1 - 0.0042 16.1 0.1 0.013 14.5 0.0 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain DUF2009 PF09418.10 ETS85640.1 - 0.3 10.1 0.0 0.41 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) GMC_oxred_N PF00732.19 ETS85641.1 - 1.6e-56 191.9 0.0 2.1e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS85641.1 - 1.5e-26 93.6 0.3 3.1e-26 92.6 0.3 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 ETS85641.1 - 0.006 15.9 0.1 0.015 14.6 0.1 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 ETS85641.1 - 0.007 15.5 0.0 1.6 7.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 ETS85641.1 - 0.013 15.1 0.1 4.7 6.7 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Glyco_hydro_3_C PF01915.22 ETS85642.1 - 2.5e-37 128.8 0.0 3.7e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS85642.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS85643.1 - 1.8e-06 28.0 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III-like domain WSC PF01822.19 ETS85643.1 - 0.00042 20.4 2.1 0.00062 19.9 2.1 1.3 1 0 0 1 1 1 1 WSC domain CARDB PF07705.11 ETS85643.1 - 0.12 12.6 0.3 0.27 11.5 0.3 1.6 1 1 0 1 1 1 0 CARDB Sugar_tr PF00083.24 ETS85644.1 - 1.5e-96 324.0 23.8 1.7e-96 323.8 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS85644.1 - 2.2e-34 118.9 45.4 1.3e-30 106.6 23.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS85644.1 - 4.4e-05 22.1 8.3 0.00079 18.0 4.0 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) SPT_ssu-like PF11779.8 ETS85644.1 - 5.1 6.8 6.4 0.86 9.3 1.9 2.1 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like DUF3328 PF11807.8 ETS85646.1 - 3.6e-37 128.3 2.2 4.4e-37 128.0 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2970 PF11174.8 ETS85647.1 - 0.13 12.1 1.4 0.3 11.0 1.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DUF3328 PF11807.8 ETS85648.1 - 1.6e-44 152.3 0.8 2.6e-44 151.6 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) APH PF01636.23 ETS85648.1 - 5e-14 52.8 0.1 1e-13 51.8 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ETS85648.1 - 0.0013 18.1 0.1 0.0022 17.4 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pro-kuma_activ PF09286.11 ETS85649.1 - 4.1e-35 121.1 0.2 1.1e-34 119.8 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ETS85649.1 - 6.9e-08 32.1 0.1 1.2e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Subtilase family MARVEL PF01284.23 ETS85651.1 - 1.8e-22 79.9 2.4 2.5e-22 79.5 2.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain fn2 PF00040.19 ETS85651.1 - 0.093 13.0 0.3 0.24 11.7 0.1 1.7 2 0 0 2 2 2 0 Fibronectin type II domain Aldo_ket_red PF00248.21 ETS85652.1 - 6.4e-69 232.4 0.0 7.9e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GP46 PF07409.12 ETS85652.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Phage protein GP46 Fungal_trans PF04082.18 ETS85653.1 - 7.1e-09 35.1 0.1 1.1e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS85653.1 - 1.9e-08 34.3 8.1 2.6e-08 33.8 8.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.6 ETS85655.1 - 3.6e-12 46.5 0.1 6.1e-12 45.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS85655.1 - 5.1e-08 32.8 0.6 8.1e-08 32.1 0.2 1.5 2 0 0 2 2 2 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 ETS85655.1 - 4.6e-07 30.2 0.7 8.3e-07 29.3 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ETS85655.1 - 2.7e-05 24.4 0.0 5.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 ETS85655.1 - 0.00013 21.5 0.1 0.018 14.5 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ETS85655.1 - 0.00093 18.4 0.0 0.063 12.4 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 ETS85655.1 - 0.0032 17.9 0.1 0.0064 16.9 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ETS85655.1 - 0.0089 16.6 0.1 0.022 15.3 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 ETS85655.1 - 0.011 16.6 0.0 0.02 15.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 3Beta_HSD PF01073.19 ETS85655.1 - 0.031 13.3 0.1 0.061 12.3 0.1 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_3 PF03447.16 ETS85655.1 - 0.057 14.1 0.3 0.12 13.0 0.3 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain tRNA_U5-meth_tr PF05958.11 ETS85656.1 - 3.5e-10 39.4 0.1 5.3e-08 32.2 0.0 3.1 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 ETS85656.1 - 5.1e-07 29.4 0.0 1.6e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 ETS85656.1 - 1.6e-05 25.5 0.0 4.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ETS85656.1 - 3.6e-05 23.5 0.0 6.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 ETS85656.1 - 4.8e-05 23.2 0.0 9.9e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ETS85656.1 - 0.0002 20.9 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ETS85656.1 - 0.00048 19.7 0.0 0.00085 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 ETS85656.1 - 0.0035 18.0 0.0 0.014 16.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS85656.1 - 0.0064 17.1 0.0 0.018 15.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 ETS85656.1 - 0.16 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 G_glu_transpept PF01019.21 ETS85657.1 - 7.4e-158 526.5 0.9 8.5e-158 526.3 0.9 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase UNC45-central PF11701.8 ETS85658.1 - 4.5e-52 176.1 0.3 3.4e-50 170.0 0.0 3.6 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central ParD PF09386.10 ETS85658.1 - 0.035 14.5 0.2 0.28 11.6 0.2 2.6 2 0 0 2 2 2 0 Antitoxin ParD Adaptin_N PF01602.20 ETS85658.1 - 0.053 12.1 0.4 0.32 9.5 0.3 2.5 2 1 0 2 2 2 0 Adaptin N terminal region Atx10homo_assoc PF09759.9 ETS85658.1 - 0.1 12.6 0.9 3.1 7.9 0.1 3.0 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Tfb4 PF03850.14 ETS85659.1 - 3.2e-91 305.7 0.0 3.7e-91 305.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Asparaginase_2 PF01112.18 ETS85660.1 - 1.3e-43 149.2 5.9 1.7e-27 96.3 0.0 3.2 3 0 0 3 3 3 3 Asparaginase Actin PF00022.19 ETS85661.1 - 4.3e-80 269.3 0.0 8.8e-78 261.7 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ETS85661.1 - 0.02 13.7 0.1 1.2 7.9 0.1 2.1 2 0 0 2 2 2 0 MreB/Mbl protein F-box PF00646.33 ETS85662.1 - 0.00075 19.3 0.8 0.0017 18.2 0.8 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ETS85662.1 - 0.0027 17.6 0.7 0.0061 16.4 0.7 1.6 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.18 ETS85663.1 - 3.6e-21 75.4 0.2 5.9e-21 74.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS85663.1 - 9.3e-06 25.7 9.6 1.6e-05 24.9 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 ETS85664.1 - 1.5e-17 63.9 0.6 1.1e-16 61.1 0.6 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS85664.1 - 0.011 15.0 0.9 0.021 14.1 0.9 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS85664.1 - 0.012 15.8 2.0 0.03 14.5 2.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 ETS85664.1 - 0.053 12.6 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Lycopene_cycl PF05834.12 ETS85664.1 - 0.15 11.0 1.5 8.4 5.3 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 ETS85664.1 - 1.2 8.6 4.2 2.1 7.9 4.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Amidohydro_2 PF04909.14 ETS85665.1 - 4.2e-35 122.0 0.1 5.2e-35 121.6 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase His_Phos_2 PF00328.22 ETS85666.1 - 0.0024 17.3 0.0 0.0081 15.6 0.1 1.9 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) DUF4305 PF14146.6 ETS85666.1 - 0.0049 17.0 2.3 0.015 15.5 2.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4305) SKG6 PF08693.10 ETS85666.1 - 2.3 7.7 10.7 0.38 10.2 6.0 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Asp PF00026.23 ETS85667.1 - 4.9e-47 160.9 3.4 5.8e-47 160.6 3.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS85667.1 - 1e-07 32.4 0.2 3.6e-06 27.3 0.2 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ETS85667.1 - 0.00035 21.1 0.0 0.35 11.5 0.1 2.9 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ETS85667.1 - 0.006 17.1 0.1 2.8 8.6 0.1 2.7 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease 2OG-FeII_Oxy_3 PF13640.6 ETS85668.1 - 2.8e-10 40.9 0.1 5e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Thioredoxin_6 PF13848.6 ETS85669.1 - 1e-23 84.2 0.0 1e-20 74.4 0.0 2.2 1 1 2 3 3 3 3 Thioredoxin-like domain Thioredoxin PF00085.20 ETS85669.1 - 1.7e-11 44.0 0.0 1.9e-09 37.5 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin DUF5611 PF18446.1 ETS85669.1 - 0.19 12.6 0.2 1.4 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5611) Myf5 PF12232.8 ETS85669.1 - 0.32 11.8 5.3 0.85 10.4 0.3 2.3 2 0 0 2 2 2 0 Myogenic determination factor 5 Glyco_hydro_61 PF03443.14 ETS85670.1 - 1.1e-59 201.9 0.7 1.3e-59 201.6 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Rep_fac_C PF08542.11 ETS85671.1 - 8.2e-17 61.4 0.0 2.2e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 ETS85671.1 - 5.8e-16 59.1 0.0 9.7e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 ETS85671.1 - 2e-13 50.5 0.0 1.2e-12 47.9 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 ETS85671.1 - 6.8e-08 32.6 0.0 1.7e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 ETS85671.1 - 2.4e-07 31.0 0.3 6.8e-07 29.5 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain AAA_30 PF13604.6 ETS85671.1 - 6.5e-07 29.3 0.1 2e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 ETS85671.1 - 6.8e-06 26.0 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.6 ETS85671.1 - 8.8e-06 25.7 0.1 8.3e-05 22.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 ETS85671.1 - 1.1e-05 25.8 0.0 4e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS85671.1 - 1.1e-05 25.9 0.0 5.3e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ETS85671.1 - 2.2e-05 24.5 0.1 5.8e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 ETS85671.1 - 3.2e-05 23.2 0.0 5.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 ETS85671.1 - 4.5e-05 23.3 0.0 8.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 ETS85671.1 - 0.00018 21.3 0.1 0.00057 19.8 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 ETS85671.1 - 0.0003 21.2 0.4 0.00093 19.5 0.1 2.0 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 ETS85671.1 - 0.00038 20.2 0.0 0.0011 18.7 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 ETS85671.1 - 0.0004 20.1 0.0 0.00069 19.4 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain PhoH PF02562.16 ETS85671.1 - 0.00049 19.6 0.6 0.57 9.6 0.0 2.5 2 1 0 3 3 2 2 PhoH-like protein AAA_14 PF13173.6 ETS85671.1 - 0.00063 19.8 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ETS85671.1 - 0.0018 17.7 0.1 0.012 15.0 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 ETS85671.1 - 0.0041 17.1 0.0 0.04 13.9 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit TniB PF05621.11 ETS85671.1 - 0.0061 16.0 0.0 0.044 13.2 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 ETS85671.1 - 0.0076 16.8 0.0 0.016 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ETS85671.1 - 0.011 15.2 0.0 0.03 13.8 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 ETS85671.1 - 0.015 15.6 0.0 0.028 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 ETS85671.1 - 0.039 13.2 0.0 0.081 12.1 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 ETS85671.1 - 0.048 13.2 0.0 0.12 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 ETS85671.1 - 0.052 13.3 0.1 0.32 10.8 0.2 2.0 1 1 1 2 2 2 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 ETS85671.1 - 0.08 13.3 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TIP49_C PF17856.1 ETS85671.1 - 0.11 12.6 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 TIP49 AAA-lid domain ATPase_2 PF01637.18 ETS85671.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Lon_2 PF13337.6 ETS85671.1 - 0.16 10.5 0.0 0.32 9.5 0.0 1.4 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease COesterase PF00135.28 ETS85672.1 - 2.8e-86 290.4 0.0 3.2e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS85672.1 - 8.1e-05 22.6 0.1 0.00038 20.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS85672.1 - 0.00013 21.5 0.1 0.00022 20.8 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 ETS85672.1 - 0.087 13.4 0.8 0.26 11.9 0.1 2.1 2 1 0 2 2 2 0 Alpha/beta hydrolase family MFS_1 PF07690.16 ETS85674.1 - 1.3e-10 40.7 60.9 5.5e-09 35.4 30.2 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.12 ETS85674.1 - 0.8 9.9 7.0 0.26 11.5 2.7 2.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Histone PF00125.24 ETS85676.1 - 1.5e-18 67.4 0.0 2e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 ETS85676.1 - 1.1e-12 47.5 0.1 2.5e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 ETS85676.1 - 2.8e-05 24.3 0.0 4.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Coprogen_oxidas PF01218.18 ETS85677.1 - 5.7e-128 425.8 0.0 6.4e-128 425.6 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase R3H PF01424.22 ETS85678.1 - 6.4e-12 45.3 0.3 1.5e-11 44.1 0.3 1.7 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 ETS85678.1 - 0.00027 20.7 0.0 0.00056 19.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FMO-like PF00743.19 ETS85679.1 - 3.7e-60 203.9 0.0 5.3e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ETS85679.1 - 1.8e-16 60.3 0.1 7.7e-15 54.9 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS85679.1 - 7.6e-16 58.2 0.1 1e-14 54.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS85679.1 - 9.3e-08 32.2 2.3 2.8e-07 30.7 0.0 2.8 3 1 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS85679.1 - 8.5e-07 28.9 1.0 0.0054 16.4 0.1 3.3 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS85679.1 - 1.4e-06 28.8 0.3 0.0054 17.3 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS85679.1 - 1.7e-06 27.5 0.2 5.9e-06 25.7 0.0 1.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 ETS85679.1 - 4.7e-06 26.1 0.1 0.097 12.0 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ETS85679.1 - 5.4e-05 22.8 0.1 0.011 15.4 0.0 2.9 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_9 PF13454.6 ETS85679.1 - 0.00017 21.6 2.5 0.26 11.3 0.3 3.5 2 1 0 2 2 2 2 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 ETS85679.1 - 0.0002 20.7 2.8 0.0013 18.0 0.0 2.8 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 ETS85679.1 - 0.00028 20.9 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 ETS85679.1 - 0.00074 18.9 0.4 1.1 8.5 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 ETS85679.1 - 0.0013 17.9 0.3 0.22 10.5 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 ETS85679.1 - 0.004 17.6 0.0 1.1 9.7 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_2 PF03446.15 ETS85679.1 - 0.018 15.2 0.0 0.048 13.8 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 ETS85679.1 - 0.019 14.6 0.2 0.045 13.3 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 ETS85679.1 - 0.03 13.6 0.1 1.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.16 ETS85679.1 - 0.041 13.5 1.2 1 9.0 0.0 3.0 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Glu_dehyd_C PF16912.5 ETS85679.1 - 0.11 11.9 0.0 0.46 9.9 0.0 1.9 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Amino_oxidase PF01593.24 ETS85679.1 - 0.15 11.4 1.5 0.26 10.5 0.0 2.1 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Tyrosinase PF00264.20 ETS85680.1 - 6.1e-35 121.5 3.2 1.2e-34 120.5 3.2 1.5 1 1 0 1 1 1 1 Common central domain of tyrosinase CoA_transf_3 PF02515.17 ETS85681.1 - 1.9e-41 142.4 0.2 8.7e-41 140.2 0.2 1.9 1 1 1 2 2 2 1 CoA-transferase family III 3HCDH_N PF02737.18 ETS85682.1 - 1.2e-47 162.1 0.0 1.7e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ETS85682.1 - 2.2e-14 53.8 0.0 6.2e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 ETS85682.1 - 0.00083 19.4 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 ETS85682.1 - 0.0027 17.1 0.1 0.019 14.4 0.0 2.0 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ETS85682.1 - 0.003 17.2 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_23 PF13489.6 ETS85682.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_2 PF03446.15 ETS85682.1 - 0.017 15.3 0.1 0.045 13.9 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 ETS85682.1 - 0.047 13.3 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 ETS85682.1 - 0.047 13.0 0.2 0.083 12.2 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 ETS85682.1 - 0.12 12.9 0.1 0.35 11.5 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ldl_recept_b PF00058.17 ETS85683.1 - 7e-15 55.2 1.4 0.1 13.1 0.0 5.6 5 1 0 5 5 5 4 Low-density lipoprotein receptor repeat class B SGL PF08450.12 ETS85683.1 - 8.7e-07 28.8 0.3 0.19 11.3 0.1 3.2 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region DUF5074 PF16819.5 ETS85683.1 - 0.0049 16.9 0.0 0.038 14.0 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF5074) DUF5050 PF16472.5 ETS85683.1 - 0.0051 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5050) polyprenyl_synt PF00348.17 ETS85684.1 - 4.9e-46 156.9 0.0 1.1e-45 155.7 0.0 1.6 2 0 0 2 2 2 1 Polyprenyl synthetase Pectinesterase PF01095.19 ETS85685.1 - 5.7e-54 182.9 10.4 7.6e-54 182.4 10.4 1.1 1 0 0 1 1 1 1 Pectinesterase Phage_T4_Ndd PF06591.11 ETS85685.1 - 0.06 13.1 1.6 1.9 8.3 0.1 2.7 2 1 1 3 3 3 0 T4-like phage nuclear disruption protein (Ndd) zf-ZPR1 PF03367.13 ETS85686.1 - 1.3e-111 369.6 0.0 5.1e-57 192.2 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.12 ETS85686.1 - 0.26 11.3 3.2 2.9 7.9 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbons zf-piccolo PF05715.13 ETS85686.1 - 5.9 7.1 10.5 31 4.8 2.1 3.3 3 0 0 3 3 3 0 Piccolo Zn-finger Rpr2 PF04032.16 ETS85687.1 - 8.3e-14 51.6 2.2 8.5e-14 51.6 0.2 1.9 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-NADH-PPase PF09297.11 ETS85687.1 - 0.004 16.8 2.1 0.035 13.8 0.2 2.3 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Herpes_UL49_1 PF03117.14 ETS85687.1 - 0.024 13.9 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 UL49 family Nudix_N_2 PF14803.6 ETS85687.1 - 0.044 13.7 0.6 2.5 8.1 0.1 2.3 2 0 0 2 2 2 0 Nudix N-terminal TF_Zn_Ribbon PF08271.12 ETS85687.1 - 0.16 11.5 0.4 22 4.7 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 ETS85687.1 - 0.53 9.8 2.8 9.4 5.8 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF1178 PF06676.11 ETS85687.1 - 0.75 10.2 3.8 0.57 10.6 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) Peptidase_M4_C PF02868.15 ETS85688.1 - 2.5e-45 154.4 0.0 8e-45 152.7 0.0 1.9 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 ETS85688.1 - 7.4e-23 81.7 3.6 1.3e-22 80.9 3.6 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain PLN_propep PF16485.5 ETS85688.1 - 3.8e-17 61.7 3.1 5.6e-11 42.0 1.2 2.5 2 0 0 2 2 2 2 Protealysin propeptide Abhydrolase_6 PF12697.7 ETS85689.1 - 2.2e-14 54.6 0.6 3.3e-14 54.0 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS85689.1 - 1.5e-11 44.0 0.1 3.8e-11 42.7 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS85689.1 - 3e-10 40.2 0.2 4.8e-09 36.2 0.3 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS85689.1 - 0.00052 19.5 0.3 0.07 12.6 0.2 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Lipase_2 PF01674.18 ETS85689.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) UPF0227 PF05728.12 ETS85689.1 - 0.03 14.2 1.4 27 4.6 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 ETS85689.1 - 0.066 12.9 0.6 0.2 11.3 0.2 1.9 2 0 0 2 2 2 0 PGAP1-like protein Lipase_3 PF01764.25 ETS85689.1 - 0.084 12.7 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF1889 PF08986.10 ETS85689.1 - 0.17 12.3 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1889) Ank_2 PF12796.7 ETS85690.1 - 1.6e-26 92.7 3.0 5.1e-07 30.2 0.0 5.3 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS85690.1 - 1.2e-20 73.6 1.4 5.9e-06 26.7 0.2 6.0 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS85690.1 - 4.1e-20 71.6 1.7 1e-05 25.7 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS85690.1 - 4.4e-16 57.4 0.1 0.06 13.9 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 ETS85690.1 - 3.9e-15 55.5 7.0 0.0093 16.4 0.0 7.7 8 0 0 8 8 8 5 Ankyrin repeat CorA PF01544.18 ETS85690.1 - 6.5e-09 35.5 0.1 1.4e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein HeLo PF14479.6 ETS85692.1 - 1.3e-47 162.3 1.8 2.3e-47 161.5 1.8 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 ETS85692.1 - 0.0043 16.5 0.0 0.0078 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS85692.1 - 0.047 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DUF1441 PF07278.11 ETS85692.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1441) 2-Hacid_dh_C PF02826.19 ETS85693.1 - 1.5e-44 151.5 0.0 3.9e-29 101.2 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain EutN_CcmL PF03319.13 ETS85693.1 - 0.0016 19.0 0.0 0.009 16.6 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation protein EutN/carboxysome Gp_dh_N PF00044.24 ETS85693.1 - 0.014 15.7 1.9 0.3 11.4 0.2 2.3 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ETS85693.1 - 0.034 13.5 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 ETS85693.1 - 0.11 12.4 0.1 0.32 10.9 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ETS85693.1 - 0.11 13.0 0.1 0.29 11.7 0.1 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 ETS85693.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Dyp_perox PF04261.12 ETS85694.1 - 4.3e-85 285.6 0.0 5.5e-85 285.2 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family DUF3328 PF11807.8 ETS85696.1 - 2.3e-49 168.1 2.8 2.9e-49 167.8 2.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF5559 PF17714.1 ETS85696.1 - 0.054 13.4 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5559) PRESAN PF09687.10 ETS85696.1 - 0.16 12.5 0.0 0.51 10.9 0.0 1.7 2 0 0 2 2 2 0 Plasmodium RESA N-terminal RPE65 PF03055.15 ETS85697.1 - 8.1e-92 308.8 0.0 9.9e-92 308.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein HET PF06985.11 ETS85699.1 - 2.1e-32 112.5 0.3 3.9e-32 111.6 0.0 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Helo_like_N PF17111.5 ETS85701.1 - 9e-24 84.0 1.5 1.2e-23 83.6 1.5 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 ETS85701.1 - 0.0081 16.3 0.2 0.0081 16.3 0.2 2.2 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases L27 PF02828.16 ETS85701.1 - 0.045 13.5 0.6 0.045 13.5 0.6 2.2 3 0 0 3 3 3 0 L27 domain Ses_B PF17046.5 ETS85701.1 - 2.4 8.2 6.8 4.2 7.4 6.8 1.3 1 0 0 1 1 1 0 SesB domain on fungal death-pathway protein FUSC PF04632.12 ETS85701.1 - 3.6 6.0 9.9 2.9 6.3 0.4 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family TPR_10 PF13374.6 ETS85702.1 - 1.9e-32 110.2 0.0 1.5e-11 43.7 0.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 ETS85702.1 - 5.4e-26 90.7 0.0 4.8e-16 58.8 0.0 4.3 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 ETS85702.1 - 8.2e-08 31.8 0.7 0.87 9.8 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.22 ETS85702.1 - 2.3e-06 27.0 0.1 9.5e-06 25.0 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain TPR_8 PF13181.6 ETS85702.1 - 6.8e-05 22.8 2.2 20 5.7 0.1 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 ETS85702.1 - 0.002 18.4 0.0 1.3 9.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat NACHT PF05729.12 ETS85702.1 - 0.0052 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_2 PF07719.17 ETS85702.1 - 0.0057 16.7 0.3 6.8 7.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 ETS85702.1 - 0.0085 16.7 0.0 0.25 12.0 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ETS85702.1 - 0.021 14.6 0.1 1.7 8.6 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 ETS85702.1 - 0.13 12.7 0.9 49 4.5 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 ETS85702.1 - 0.33 11.7 4.0 4.5 8.2 0.0 3.9 5 0 0 5 5 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 ETS85703.1 - 7.2e-29 100.2 0.5 4.9e-10 39.9 0.2 4.4 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS85703.1 - 5.9e-27 93.4 2.4 2.5e-07 30.9 0.1 5.9 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS85703.1 - 6.1e-23 78.4 0.2 0.00083 19.6 0.0 8.5 9 0 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.6 ETS85703.1 - 5.3e-21 74.7 0.8 7e-05 23.3 0.0 7.0 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 ETS85703.1 - 2.5e-17 62.4 4.1 1.5e-05 25.2 0.0 7.3 8 0 0 8 8 8 3 Ankyrin repeat Helo_like_N PF17111.5 ETS85703.1 - 6.1e-13 48.6 0.1 9.4e-13 48.0 0.1 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 ETS85703.1 - 5e-06 26.7 0.5 9.1e-05 22.6 0.1 2.5 1 1 1 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Laminin_II PF06009.12 ETS85703.1 - 0.045 13.8 0.2 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Laminin Domain II B2 PF11473.8 ETS85703.1 - 0.068 13.0 0.0 0.3 10.9 0.0 2.1 1 0 0 1 1 1 0 RNA binding protein B2 TOH_N PF12549.8 ETS85703.1 - 0.14 12.0 0.2 0.37 10.7 0.2 1.7 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal Filament PF00038.21 ETS85703.1 - 0.16 11.6 1.4 0.31 10.6 0.1 1.9 2 0 0 2 2 2 0 Intermediate filament protein PTR2 PF00854.21 ETS85704.1 - 1.1e-61 208.9 6.1 1.6e-61 208.3 5.4 1.6 1 1 0 1 1 1 1 POT family FMO-like PF00743.19 ETS85705.1 - 2.4e-13 49.4 0.0 5.4e-12 44.9 0.0 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ETS85705.1 - 1.5e-09 37.9 0.0 3.6e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS85705.1 - 6.2e-06 25.6 0.0 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS85705.1 - 3.3e-05 23.2 0.0 0.00014 21.1 0.0 2.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ETS85705.1 - 3.4e-05 23.3 0.0 0.0027 17.0 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS85705.1 - 0.00097 18.8 0.0 0.07 12.7 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS85705.1 - 0.0052 16.8 0.1 0.047 13.7 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Cupin_2 PF07883.11 ETS85706.1 - 0.025 14.3 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Cupin domain Glyco_transf_28 PF03033.20 ETS85707.1 - 9.3e-17 61.4 0.1 9.2e-16 58.1 0.1 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 ETS85707.1 - 3.5e-08 32.7 0.0 7.5e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 ETS85707.1 - 0.00029 21.1 0.2 0.0016 18.8 0.1 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 ETS85707.1 - 0.0039 17.2 1.6 0.0067 16.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Thioredoxin_10 PF17991.1 ETS85707.1 - 0.18 12.3 0.7 0.4 11.2 0.7 1.5 1 0 0 1 1 1 0 Thioredoxin like C-terminal domain Zn_clus PF00172.18 ETS85709.1 - 2.2e-09 37.3 10.0 4.5e-09 36.3 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS85709.1 - 0.0024 16.7 1.1 0.0064 15.3 0.4 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain COesterase PF00135.28 ETS85710.1 - 1.4e-96 324.5 0.0 1.6e-96 324.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS85710.1 - 1.3e-06 28.5 0.4 5e-06 26.5 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold MKLP1_Arf_bdg PF16540.5 ETS85711.1 - 0.0063 16.6 1.3 0.0069 16.4 0.4 1.6 1 1 1 2 2 2 1 Arf6-interacting domain of mitotic kinesin-like protein 1 Tnp_DNA_bind PF14706.6 ETS85711.1 - 0.04 13.8 0.2 0.074 12.9 0.2 1.5 1 0 0 1 1 1 0 Transposase DNA-binding TMEM214 PF10151.9 ETS85711.1 - 1.5 7.2 5.8 1.9 6.8 5.8 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator AAA_13 PF13166.6 ETS85711.1 - 1.9 7.1 13.7 2.1 6.9 13.7 1.0 1 0 0 1 1 1 0 AAA domain YEATS PF03366.16 ETS85712.1 - 4.8e-27 93.7 0.5 9.9e-27 92.7 0.5 1.5 1 1 0 1 1 1 1 YEATS family Epimerase PF01370.21 ETS85713.1 - 1.2e-05 25.0 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS85713.1 - 6.9e-05 22.8 0.0 0.0011 18.9 0.0 2.6 2 1 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ETS85713.1 - 0.0016 17.5 0.0 0.006 15.6 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ETS85713.1 - 0.011 14.9 0.0 0.14 11.2 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ETS85713.1 - 0.062 12.7 0.0 0.081 12.3 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ETS85713.1 - 0.11 11.6 0.0 0.69 9.0 0.0 2.2 2 1 0 2 2 2 0 Male sterility protein Ins_P5_2-kin PF06090.12 ETS85715.1 - 5.8e-38 131.1 0.0 3.5e-37 128.6 0.0 1.9 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Nucleoside_tran PF01733.18 ETS85716.1 - 7.1e-37 127.4 6.6 7.1e-37 127.4 6.6 2.6 2 1 0 2 2 2 1 Nucleoside transporter TMEM132D_C PF15706.5 ETS85716.1 - 2.3 8.0 0.0 2.3 8.0 0.0 2.8 4 0 0 4 4 4 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Pkinase PF00069.25 ETS85717.1 - 4.3e-67 226.3 5.4 1e-66 225.0 2.6 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS85717.1 - 5.5e-53 179.9 0.2 1e-52 179.0 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ETS85717.1 - 3.4e-23 81.8 0.0 7.7e-23 80.6 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 ETS85717.1 - 8.3e-07 28.6 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 ETS85717.1 - 3.2e-06 27.5 0.2 1.2e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Pkinase_fungal PF17667.1 ETS85717.1 - 3.9e-06 25.9 0.5 1.4e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ETS85717.1 - 0.0035 17.3 3.6 0.0071 16.3 0.1 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family PH PF00169.29 ETS85717.1 - 0.014 15.9 0.0 0.04 14.4 0.0 1.8 1 0 0 1 1 1 0 PH domain Haspin_kinase PF12330.8 ETS85717.1 - 0.032 13.2 0.4 0.069 12.1 0.4 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 ETS85717.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DDRGK PF09756.9 ETS85717.1 - 0.19 11.3 8.3 0.43 10.2 8.3 1.5 1 0 0 1 1 1 0 DDRGK domain HGTP_anticodon PF03129.20 ETS85718.1 - 2.4e-22 78.9 0.4 7.8e-22 77.3 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ETS85718.1 - 2.7e-08 34.0 0.0 1.1e-07 32.0 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Brix PF04427.18 ETS85719.1 - 1.9e-23 83.6 0.0 3e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.10 ETS85719.1 - 0.63 9.3 23.1 0.91 8.8 23.1 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 ETS85719.1 - 2.4 6.3 24.1 3.2 5.8 24.1 1.1 1 0 0 1 1 1 0 Nop14-like family Kinetochor_Ybp2 PF08568.10 ETS85720.1 - 7.8e-99 331.9 0.0 1e-98 331.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin SYF2 PF08231.12 ETS85721.1 - 6.9e-54 182.6 15.3 6.9e-54 182.6 15.3 2.1 2 0 0 2 2 2 1 SYF2 splicing factor Trypan_PARP PF05887.11 ETS85721.1 - 1.4 8.9 11.6 2.8 7.9 11.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) BNIP3 PF06553.12 ETS85721.1 - 1.5 8.5 7.7 2.3 7.8 7.7 1.5 1 0 0 1 1 1 0 BNIP3 EMC3_TMCO1 PF01956.16 ETS85721.1 - 8.1 6.1 9.7 0.24 11.1 0.7 2.6 2 1 1 3 3 3 0 Integral membrane protein EMC3/TMCO1-like Kelch_5 PF13854.6 ETS85723.1 - 8.4e-18 64.0 17.2 3.9e-11 42.7 1.6 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 ETS85723.1 - 1.7e-10 40.7 10.6 0.00033 20.6 0.1 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 ETS85723.1 - 2.1e-07 31.0 19.4 0.031 14.6 0.1 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 ETS85723.1 - 0.00075 19.0 10.3 0.72 9.5 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 ETS85723.1 - 0.025 14.6 7.6 0.42 10.7 0.0 4.7 5 0 0 5 5 5 0 Kelch motif DUF4690 PF15756.5 ETS85723.1 - 0.33 11.6 2.0 20 5.9 0.1 2.6 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Kelch_3 PF13415.6 ETS85723.1 - 0.47 10.8 10.7 0.35 11.2 0.3 4.8 5 0 0 5 5 5 0 Galactose oxidase, central domain HET PF06985.11 ETS85724.1 - 5.7e-36 124.1 0.1 8e-36 123.6 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) T2SSM_b PF10741.9 ETS85724.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b Ecl1 PF12855.7 ETS85726.1 - 1.2e-36 127.5 27.6 1.2e-36 127.5 27.6 1.8 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 ETS85726.1 - 0.078 13.1 1.1 0.15 12.2 1.1 1.4 1 0 0 1 1 1 0 MYND finger zf-FLZ PF04570.14 ETS85726.1 - 0.99 8.9 4.6 3.9 7.0 4.6 1.9 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 YL1 PF05764.13 ETS85727.1 - 1.6e-72 244.5 31.5 1.6e-72 244.5 31.5 3.3 4 0 0 4 4 4 1 YL1 nuclear protein YL1_C PF08265.11 ETS85727.1 - 1.7e-12 46.9 4.2 2.3e-12 46.4 1.4 2.3 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain DUF2423 PF10338.9 ETS85728.1 - 4.3e-18 65.3 2.5 4.3e-18 65.3 2.5 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) DUF3438 PF11920.8 ETS85728.1 - 0.034 13.4 1.1 0.04 13.2 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) HMG14_17 PF01101.18 ETS85728.1 - 0.28 12.1 15.1 0.032 15.2 10.6 1.8 1 1 1 2 2 2 0 HMG14 and HMG17 SAP PF02037.27 ETS85729.1 - 1.1e-05 25.1 0.1 1.4e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 SAP domain PINIT PF14324.6 ETS85730.1 - 5.8e-42 143.5 0.0 1.1e-41 142.6 0.0 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 ETS85730.1 - 3.4e-20 71.5 4.7 3.4e-20 71.5 4.7 1.7 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 ETS85730.1 - 3.2e-07 30.0 1.0 8.5e-07 28.7 1.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 ETS85730.1 - 0.019 14.8 4.9 0.038 13.8 4.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ETS85730.1 - 0.29 11.1 3.5 0.6 10.1 3.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ETS85730.1 - 2.1 8.6 5.9 3.6 7.8 5.9 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TRAPP PF04051.16 ETS85731.1 - 1.4e-46 157.8 0.0 1.8e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Secretin_N PF03958.17 ETS85731.1 - 2.2 8.7 4.5 4.9 7.6 4.5 1.5 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain Ldh_1_C PF02866.18 ETS85732.1 - 2.6e-46 157.6 0.0 3.9e-46 157.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 ETS85732.1 - 4.8e-44 149.9 0.1 6.7e-44 149.4 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 ETS85732.1 - 0.0077 15.3 0.0 0.012 14.7 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ribosomal_L28e PF01778.17 ETS85733.1 - 2.4e-36 124.9 1.2 3.1e-36 124.6 1.2 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Adeno_terminal PF02459.15 ETS85733.1 - 0.015 13.7 0.4 0.016 13.6 0.4 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Dmrt1 PF12374.8 ETS85733.1 - 1.1 9.8 6.0 0.65 10.5 0.3 2.8 3 0 0 3 3 3 0 Double-sex mab3 related transcription factor 1 DUF2015 PF09435.10 ETS85734.1 - 3.2e-47 159.0 0.0 3.7e-47 158.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) FA_hydroxylase PF04116.13 ETS85735.1 - 5.2e-25 88.3 15.1 5.2e-25 88.3 15.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Tyrosinase PF00264.20 ETS85736.1 - 5e-45 154.5 0.6 7.9e-45 153.9 0.6 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 ETS85736.1 - 3.8e-28 98.6 0.0 6.2e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain ABC_membrane PF00664.23 ETS85737.1 - 1.1e-101 340.1 31.6 2.3e-53 181.6 13.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ETS85737.1 - 3.4e-70 234.9 0.0 4.2e-35 121.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ETS85737.1 - 3.4e-15 56.1 5.0 8.2e-05 22.1 0.1 4.9 3 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ETS85737.1 - 2.5e-10 41.0 3.4 0.00015 22.2 0.6 3.1 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ETS85737.1 - 1.7e-08 34.5 0.0 0.00098 19.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ETS85737.1 - 6.2e-08 33.0 0.2 0.0051 17.1 0.0 3.4 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 ETS85737.1 - 1.4e-07 30.7 0.1 0.0078 15.0 0.1 2.7 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 ETS85737.1 - 1.6e-06 28.1 0.1 0.14 11.9 0.1 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ETS85737.1 - 2e-06 27.5 0.2 0.03 14.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 ETS85737.1 - 4.5e-06 26.6 0.0 0.078 12.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 ETS85737.1 - 5.8e-06 26.2 1.2 0.1 12.3 0.0 3.2 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 ETS85737.1 - 6.4e-05 23.1 2.2 0.5 10.6 0.1 3.5 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 ETS85737.1 - 0.00014 22.4 0.0 0.25 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 ETS85737.1 - 0.00039 19.8 0.0 0.14 11.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 ETS85737.1 - 0.0016 18.8 0.0 12 6.4 0.0 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 ETS85737.1 - 0.0043 17.1 0.0 0.57 10.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 ETS85737.1 - 0.0046 17.2 0.5 7.6 6.7 0.1 3.5 3 1 0 3 3 2 0 AAA domain G-alpha PF00503.20 ETS85737.1 - 0.0096 15.1 0.0 0.89 8.6 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_18 PF13238.6 ETS85737.1 - 0.014 16.0 0.0 9.3 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ETS85737.1 - 0.017 14.7 0.9 1.5 8.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 ETS85737.1 - 0.019 14.9 0.1 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_5 PF07728.14 ETS85737.1 - 0.02 14.9 0.2 5.3 7.0 0.0 3.1 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 ETS85737.1 - 0.021 14.9 0.0 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain PRK PF00485.18 ETS85737.1 - 0.022 14.5 0.0 4.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Vma12 PF11712.8 ETS85737.1 - 0.023 14.8 2.2 5.6 7.0 0.0 3.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase AAA_33 PF13671.6 ETS85737.1 - 0.035 14.3 0.0 4.4 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ETS85737.1 - 0.065 12.9 0.0 9.8 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ETS85737.1 - 0.082 13.3 0.1 12 6.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 ETS85737.1 - 0.1 12.1 0.0 17 4.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF3328 PF11807.8 ETS85739.1 - 2.2e-48 164.9 0.0 2.8e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) RNA_pol_3_Rpc31 PF11705.8 ETS85740.1 - 0.068 13.4 7.4 0.084 13.1 7.4 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 ETS85740.1 - 0.87 8.8 9.9 1.1 8.5 9.9 1.1 1 0 0 1 1 1 0 NOA36 protein EBV-NA3 PF05009.12 ETS85740.1 - 1.2 8.6 3.2 1.4 8.4 3.2 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) WD40 PF00400.32 ETS85741.1 - 4.3e-59 195.1 13.9 1e-08 35.7 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS85741.1 - 5.3e-16 58.7 0.0 0.0026 18.0 0.0 5.7 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 ETS85741.1 - 1.8e-14 53.7 11.9 3.8e-14 52.7 11.9 1.5 1 1 0 1 1 1 1 Tup N-terminal Ge1_WD40 PF16529.5 ETS85741.1 - 2e-07 30.3 0.2 0.17 10.8 0.0 5.0 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ETS85741.1 - 3.8e-06 26.4 0.0 0.18 11.1 0.0 4.6 4 1 1 5 5 5 2 WD40-like domain Nup160 PF11715.8 ETS85741.1 - 0.0019 16.9 0.1 1.4 7.5 0.0 3.2 1 1 1 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.12 ETS85741.1 - 0.027 14.4 0.0 9.9 6.2 0.0 4.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 ETS85741.1 - 0.027 13.0 1.5 0.34 9.4 0.1 2.8 2 1 1 3 3 3 0 Cytochrome D1 heme domain Nbas_N PF15492.6 ETS85741.1 - 0.091 12.1 0.1 21 4.3 0.0 3.0 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF4604 PF15377.6 ETS85742.1 - 0.15 12.4 14.5 1 9.8 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4604) JSRP PF15312.6 ETS85743.1 - 0.12 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein HET PF06985.11 ETS85745.1 - 1.7e-15 57.7 1.6 5.6e-15 56.0 1.6 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CSN7a_helixI PF18392.1 ETS85745.1 - 0.078 12.9 0.2 0.24 11.3 0.2 1.8 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain Tim17 PF02466.19 ETS85748.1 - 1.4e-24 86.6 3.0 2e-24 86.1 3.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2428 PF10350.9 ETS85749.1 - 1.5e-64 217.9 1.6 1.5e-64 217.9 1.6 2.7 3 0 0 3 3 3 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 ETS85749.1 - 0.0008 19.5 11.0 6.3 7.3 0.1 6.6 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 ETS85749.1 - 0.013 15.8 5.4 0.097 13.1 1.1 4.3 5 0 0 5 5 5 0 HEAT repeats Not3 PF04065.15 ETS85749.1 - 0.014 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component DUF3074 PF11274.8 ETS85750.1 - 1.1e-57 195.0 1.8 3.6e-57 193.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) WSC PF01822.19 ETS85751.1 - 6.8e-18 64.6 8.5 1.5e-17 63.6 8.5 1.6 1 0 0 1 1 1 1 WSC domain Fungal_lectin PF07938.12 ETS85752.1 - 2e-10 40.5 0.2 3.4e-10 39.8 0.2 1.4 1 1 0 1 1 1 1 Fungal fucose-specific lectin SH3_15 PF18346.1 ETS85752.1 - 0.0019 18.4 0.0 0.004 17.4 0.0 1.6 1 1 0 1 1 1 1 Mind bomb SH3 repeat domain Steroid_dh PF02544.16 ETS85753.1 - 2.9e-14 53.3 0.2 2.9e-14 53.3 0.2 1.9 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 ETS85753.1 - 0.0026 17.3 0.1 0.0026 17.3 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PD-C2-AF1 PF09310.10 ETS85753.1 - 0.05 13.0 0.3 0.072 12.5 0.3 1.3 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 2OG-FeII_Oxy_2 PF13532.6 ETS85754.1 - 2.1e-12 47.6 0.0 6.5e-12 46.0 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 ETS85755.1 - 7.1e-26 90.6 2.5 6.9e-10 39.4 0.1 3.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS85755.1 - 1.1e-13 51.4 0.0 0.01 16.4 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS85755.1 - 2.4e-10 40.5 1.1 0.021 15.2 0.1 5.0 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 ETS85755.1 - 3e-10 40.1 1.6 0.00028 21.2 0.1 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 ETS85755.1 - 5.4e-10 38.6 0.2 0.041 14.4 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat MMR_HSR1_Xtn PF16897.5 ETS85756.1 - 1.3e-41 140.9 0.6 1.9e-40 137.2 0.4 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 ETS85756.1 - 5.2e-21 74.9 0.0 2.8e-20 72.5 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 ETS85756.1 - 3.3e-20 71.9 0.0 6.8e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 ETS85756.1 - 3.3e-09 36.5 0.0 1.6e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 ETS85756.1 - 0.00027 20.5 0.1 9.9 5.6 0.0 3.6 2 2 2 4 4 4 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ETS85756.1 - 0.00047 20.2 0.1 0.12 12.4 0.0 2.3 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 ETS85756.1 - 0.0082 15.1 0.2 0.026 13.5 0.1 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 ETS85756.1 - 0.024 14.6 1.5 6.6 6.6 0.0 3.2 3 0 0 3 3 3 0 RsgA GTPase Arf PF00025.21 ETS85756.1 - 0.06 12.8 0.1 10 5.6 0.1 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 ETS85756.1 - 0.061 13.5 0.1 2 8.7 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 ETS85756.1 - 0.063 13.5 0.1 0.75 10.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain HTH_Tnp_Tc5 PF03221.16 ETS85757.1 - 1.4e-10 41.1 0.1 5.3e-10 39.2 0.1 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 ETS85757.1 - 6.7e-07 28.9 1.4 2.7e-06 26.9 0.1 2.3 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 ETS85757.1 - 0.0043 16.9 0.0 0.041 13.8 0.0 2.4 2 0 0 2 2 2 1 MarR family PXA PF02194.15 ETS85758.1 - 2.6e-46 157.9 0.4 4.1e-46 157.2 0.4 1.3 1 0 0 1 1 1 1 PXA domain zf-Mss51 PF13824.6 ETS85759.1 - 1.3e-28 98.9 7.9 1.3e-28 98.9 7.9 1.9 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 ETS85759.1 - 0.0017 18.4 1.6 0.0017 18.4 1.6 2.2 2 0 0 2 2 2 1 MYND finger zf-ACC PF17848.1 ETS85759.1 - 9.1 6.5 6.7 11 6.2 1.6 3.2 3 1 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain MMS1_N PF10433.9 ETS85760.1 - 5.7e-159 529.9 0.0 9.6e-159 529.1 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 ETS85760.1 - 4e-100 335.3 0.0 3.5e-99 332.2 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region UBM PF14377.6 ETS85760.1 - 0.16 11.4 2.8 1 8.9 0.4 2.6 2 0 0 2 2 2 0 Ubiquitin binding region LysM PF01476.20 ETS85761.1 - 0.00023 21.2 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 LysM domain UBA_4 PF14555.6 ETS85761.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain VASt PF16016.5 ETS85762.1 - 6.8e-35 120.7 0.5 1.7e-34 119.4 0.5 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 ETS85762.1 - 9.8e-16 58.2 0.0 1.8e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 ETS85762.1 - 1.1e-05 25.9 0.1 4e-05 24.1 0.1 2.1 1 0 0 1 1 1 1 PH domain GRAM PF02893.20 ETS85762.1 - 0.00016 21.5 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Myosin_TH1 PF06017.13 ETS85762.1 - 0.0053 16.5 0.2 0.027 14.1 0.0 2.2 3 0 0 3 3 3 1 Unconventional myosin tail, actin- and lipid-binding BAR PF03114.18 ETS85762.1 - 0.025 14.2 0.6 0.051 13.2 0.6 1.4 1 0 0 1 1 1 0 BAR domain Thioredoxin PF00085.20 ETS85762.1 - 0.16 12.0 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin Peptidase_M4_C PF02868.15 ETS85764.1 - 9.6e-21 74.4 0.7 1.6e-20 73.6 0.7 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 ETS85764.1 - 1.5e-20 74.2 0.0 3.7e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Abhydrolase_3 PF07859.13 ETS85765.1 - 4.9e-45 154.0 0.0 1.4e-44 152.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS85765.1 - 0.0001 21.4 1.1 0.0006 18.8 1.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family LRR_4 PF12799.7 ETS85766.1 - 1.4e-13 50.7 2.6 0.0033 17.8 0.2 4.1 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ETS85766.1 - 1.2e-12 47.4 16.6 7.7e-07 28.8 3.7 3.6 2 1 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 ETS85766.1 - 0.00043 20.4 5.7 21 6.2 0.0 5.8 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.6 ETS85766.1 - 0.0016 18.0 0.7 0.0055 16.2 0.4 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 ETS85766.1 - 0.15 12.2 10.2 4.3 7.6 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich repeat HEPN_Toprim_N PF18871.1 ETS85767.1 - 0.69 9.8 6.6 0.32 10.9 2.1 2.6 2 1 0 2 2 2 0 HEPN/Toprim N-terminal domain 1 Helo_like_N PF17111.5 ETS85767.1 - 1.4 8.3 7.3 3.9 6.8 0.0 2.9 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins ATP-synt_DE_N PF02823.16 ETS85768.1 - 1.6e-17 63.2 0.0 2.2e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF2457 PF10446.9 ETS85769.1 - 3.8e-174 580.2 27.2 3.8e-174 580.2 27.2 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2457) Arf PF00025.21 ETS85770.1 - 3.3e-66 222.0 0.0 3.7e-66 221.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 ETS85770.1 - 7.3e-11 41.8 0.1 3.3e-07 29.8 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 ETS85770.1 - 9e-08 31.7 0.0 1.1e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 ETS85770.1 - 9.6e-08 32.3 0.0 3.2e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ETS85770.1 - 1.2e-07 31.4 0.0 1.6e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 ETS85770.1 - 3.2e-07 30.4 0.0 4.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ETS85770.1 - 7e-06 25.6 0.0 8e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ETS85770.1 - 0.0014 18.2 0.0 0.052 13.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF3336 PF11815.8 ETS85771.1 - 3.7e-49 166.0 5.1 5.8e-49 165.4 5.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 ETS85771.1 - 2.3e-17 63.9 0.1 1.3e-16 61.5 0.0 2.3 2 1 0 2 2 2 1 Patatin-like phospholipase Dioxygenase_C PF00775.21 ETS85772.1 - 1.3e-06 28.0 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase DUF5111 PF17138.4 ETS85772.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5111) Tyrosinase PF00264.20 ETS85773.1 - 3e-53 181.4 0.4 4.3e-53 180.9 0.4 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase zf-HC5HC2H_2 PF13832.6 ETS85774.1 - 6e-34 116.5 6.5 6e-34 116.5 6.5 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 ETS85774.1 - 2.3e-29 102.8 0.5 2.3e-29 102.8 0.5 2.2 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 ETS85774.1 - 8.4e-26 90.1 6.2 8.4e-26 90.1 6.2 2.7 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 ETS85774.1 - 3.4e-14 52.1 1.9 3.4e-14 52.1 1.9 2.3 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 ETS85774.1 - 3e-09 36.6 24.2 1.3e-08 34.6 9.5 2.7 2 0 0 2 2 2 2 PHD-finger FliN_N PF16973.5 ETS85774.1 - 0.12 12.3 0.7 0.39 10.6 0.7 1.9 1 0 0 1 1 1 0 Flagellar motor switch protein FliN N-terminal Metallophos PF00149.28 ETS85775.1 - 2.4e-40 139.2 0.1 3.1e-40 138.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ETS85775.1 - 5.9e-23 81.1 1.8 8.5e-23 80.5 1.1 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain DUF4049 PF13258.6 ETS85775.1 - 0.021 13.9 0.0 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4049) Rdx PF10262.9 ETS85776.1 - 1.7e-34 117.8 0.0 2.5e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Rdx family K_channel_TID PF07941.11 ETS85776.1 - 0.0098 16.3 7.3 0.096 13.2 1.1 2.4 2 0 0 2 2 2 2 Potassium channel Kv1.4 tandem inactivation domain G-gamma PF00631.22 ETS85777.1 - 3.3e-25 87.9 0.0 6e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 GGL domain PCI PF01399.27 ETS85778.1 - 3.1e-07 30.9 0.0 3.1e-07 30.9 0.0 2.7 3 0 0 3 3 3 1 PCI domain WSC PF01822.19 ETS85780.1 - 1e-30 105.8 26.2 8.9e-18 64.3 8.4 5.5 4 2 1 5 5 5 2 WSC domain Glyco_tranf_2_3 PF13641.6 ETS85781.1 - 1.5e-24 87.2 0.0 2.5e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ETS85781.1 - 3e-09 37.1 0.9 3e-09 37.1 0.9 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ETS85781.1 - 7.8e-05 22.2 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ETS85781.1 - 0.00035 20.4 0.0 0.00066 19.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 CoA_transf_3 PF02515.17 ETS85783.1 - 2.2e-37 129.0 0.0 7e-36 124.1 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III Fungal_trans PF04082.18 ETS85784.1 - 7e-20 71.2 0.0 2.4e-19 69.4 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Biotin_lipoyl PF00364.22 ETS85785.1 - 1.7e-20 72.6 0.6 3.1e-20 71.8 0.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 ETS85785.1 - 4.5e-09 36.5 0.0 1.3e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 ETS85785.1 - 6.1e-05 22.8 0.0 0.00034 20.4 0.0 2.1 2 0 0 2 2 2 1 Biotin-lipoyl like Sulfotransfer_4 PF17784.1 ETS85787.1 - 2.2e-60 204.1 0.0 3e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ETS85787.1 - 0.00061 20.2 0.6 0.45 10.9 0.0 2.9 2 1 1 3 3 3 2 Sulfotransferase family Nucleoporin_FG PF13634.6 ETS85788.1 - 0.037 14.9 0.3 0.089 13.6 0.3 1.7 1 0 0 1 1 1 0 Nucleoporin FG repeat region HET PF06985.11 ETS85789.1 - 2.3e-24 86.4 0.0 6.9e-24 84.9 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_4 PF13637.6 ETS85790.1 - 2.4e-25 88.5 0.2 3e-07 30.8 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS85790.1 - 1.1e-22 80.3 0.0 0.0001 22.8 0.0 6.2 5 1 0 6 6 6 4 Ankyrin repeats (3 copies) Pkinase PF00069.25 ETS85790.1 - 6.1e-18 65.1 0.0 1.7e-17 63.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.6 ETS85790.1 - 1.1e-17 62.2 1.3 0.00058 20.1 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 ETS85790.1 - 5.6e-17 61.6 0.0 0.00051 20.3 0.0 5.1 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 ETS85790.1 - 1.1e-16 60.4 2.8 0.00017 21.9 0.1 5.9 5 0 0 5 5 5 3 Ankyrin repeat Pkinase_Tyr PF07714.17 ETS85790.1 - 2.9e-10 39.9 0.0 4.9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CDC37_C PF08564.10 ETS85790.1 - 0.14 12.3 0.0 0.82 9.8 0.0 2.1 2 0 0 2 2 2 0 Cdc37 C terminal domain HeLo PF14479.6 ETS85791.1 - 3.9e-10 39.9 0.0 7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation GMC_oxred_C PF05199.13 ETS85792.1 - 1.3e-21 77.6 0.1 1.5e-21 77.5 0.1 1.0 1 0 0 1 1 1 1 GMC oxidoreductase MFS_1 PF07690.16 ETS85793.1 - 6.7e-08 31.8 3.2 7.8e-08 31.6 3.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS85793.1 - 0.001 18.0 2.0 0.0058 15.5 0.1 1.8 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ETS85794.1 - 2.3e-10 39.9 20.5 2.6e-10 39.8 20.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Cutinase PF01083.22 ETS85795.1 - 6.6e-35 120.7 4.4 8.2e-35 120.4 4.4 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 ETS85795.1 - 0.075 12.6 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 PE-PPE domain Lipase_3 PF01764.25 ETS85796.1 - 3.1e-22 79.0 0.0 4.3e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ETS85796.1 - 0.00031 21.4 0.2 0.00039 21.1 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF726 PF05277.12 ETS85796.1 - 0.0011 18.0 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) PAF-AH_p_II PF03403.13 ETS85796.1 - 0.0026 16.3 0.0 0.0038 15.8 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.20 ETS85796.1 - 0.0033 17.1 0.2 0.0061 16.2 0.2 1.4 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 ETS85796.1 - 0.023 14.0 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 ETS85796.1 - 0.045 13.3 0.1 0.071 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 ETS85796.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase GMC_oxred_N PF00732.19 ETS85797.1 - 2.2e-60 204.5 0.0 2.8e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS85797.1 - 1e-31 110.4 0.0 2e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ETS85797.1 - 0.00013 21.2 0.1 0.00019 20.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ETS85797.1 - 0.00072 18.7 0.5 0.95 8.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 ETS85797.1 - 0.0056 16.3 0.2 0.027 14.1 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS85797.1 - 0.019 15.5 0.0 0.19 12.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS85797.1 - 0.019 15.2 0.1 0.044 14.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ETS85797.1 - 0.059 12.2 0.2 0.093 11.6 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 ETS85797.1 - 0.13 11.4 0.5 0.25 10.5 0.2 1.5 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 ETS85797.1 - 0.18 12.1 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain p450 PF00067.22 ETS85798.1 - 3e-39 135.1 0.0 5.6e-38 130.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 HET PF06985.11 ETS85799.1 - 3.8e-28 98.7 0.1 7.7e-28 97.7 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TCP PF03634.13 ETS85799.1 - 0.18 12.3 0.1 0.35 11.4 0.1 1.4 1 0 0 1 1 1 0 TCP family transcription factor HET PF06985.11 ETS85800.1 - 1.6e-33 116.1 0.4 2.7e-33 115.4 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3176 PF11374.8 ETS85801.1 - 3.8e-32 110.7 0.4 3.8e-32 110.7 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) KR PF08659.10 ETS85802.1 - 3e-35 121.8 0.0 4e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 KR domain BRE PF06113.12 ETS85803.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) AAA PF00004.29 ETS85805.1 - 9.5e-20 71.4 0.0 2e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS85805.1 - 0.0011 19.4 2.2 0.0039 17.6 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ETS85805.1 - 0.0011 19.2 0.4 0.29 11.4 0.0 3.1 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 ETS85805.1 - 0.0015 18.8 0.0 0.11 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ETS85805.1 - 0.0017 18.4 0.0 0.0046 16.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 ETS85805.1 - 0.02 15.1 0.8 0.058 13.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 ETS85805.1 - 0.03 14.1 0.1 0.03 14.1 0.1 2.7 3 1 0 3 3 3 0 AAA domain AAA_6 PF12774.7 ETS85805.1 - 0.089 11.7 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region RuvB_N PF05496.12 ETS85805.1 - 0.11 12.3 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ETS85805.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_30 PF13604.6 ETS85805.1 - 0.19 11.4 2.1 0.25 11.0 0.3 2.1 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ETS85806.1 - 5.7e-33 114.3 0.0 1.8e-32 112.8 0.0 1.9 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ETS85806.1 - 1.7e-30 106.6 10.8 3.5e-30 105.6 10.8 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ETS85806.1 - 1.9e-06 27.5 0.1 5.1e-05 22.8 0.0 2.0 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF815 PF05673.13 ETS85806.1 - 0.0063 15.7 0.2 0.014 14.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 ETS85806.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 ETS85806.1 - 0.014 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 ETS85806.1 - 0.022 14.5 0.1 0.069 12.9 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ETS85806.1 - 0.032 14.6 0.6 0.076 13.4 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 ETS85806.1 - 0.037 14.5 0.0 0.52 10.7 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 ETS85806.1 - 0.042 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 ETS85806.1 - 0.059 13.6 0.1 1.1 9.5 0.1 2.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit HRI1 PF16815.5 ETS85807.1 - 3.2e-07 30.3 0.0 0.0052 16.5 0.0 2.1 1 1 0 2 2 2 2 Protein HRI1 TRAM_LAG1_CLN8 PF03798.16 ETS85808.1 - 1e-36 126.6 20.7 1e-36 126.6 20.7 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 ETS85808.1 - 2e-26 91.4 0.1 5.8e-26 89.9 0.1 1.8 1 0 0 1 1 1 1 TRAM1-like protein PalH PF08733.10 ETS85809.1 - 1.5e-116 389.0 0.0 2e-116 388.6 0.0 1.0 1 0 0 1 1 1 1 PalH/RIM21 AAA PF00004.29 ETS85811.1 - 1.9e-98 326.0 0.0 1.1e-47 161.8 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ETS85811.1 - 2.2e-23 81.8 3.6 9.9e-13 47.7 0.4 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 ETS85811.1 - 1.8e-19 69.7 0.4 7.4e-19 67.7 0.4 2.2 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 ETS85811.1 - 3.5e-14 52.8 0.0 6e-06 26.1 0.0 3.2 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ETS85811.1 - 9.9e-14 51.8 0.0 3e-07 30.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 ETS85811.1 - 3.7e-13 50.2 0.0 0.00021 21.7 0.0 4.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 ETS85811.1 - 2.6e-12 47.1 0.0 3.4e-05 24.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ETS85811.1 - 3.2e-12 46.6 0.3 3.5e-06 27.1 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ETS85811.1 - 2.3e-09 36.9 0.9 0.0014 17.9 0.0 3.3 3 1 0 3 3 3 2 TIP49 P-loop domain AAA_22 PF13401.6 ETS85811.1 - 2.4e-09 37.6 0.4 0.028 14.7 0.1 3.9 2 2 1 3 3 2 2 AAA domain CDC48_2 PF02933.17 ETS85811.1 - 1.8e-08 34.0 0.1 5.2e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.6 ETS85811.1 - 1.8e-07 31.8 0.0 0.026 15.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 ETS85811.1 - 2.1e-07 30.5 0.2 0.0069 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 ETS85811.1 - 3.4e-07 30.2 0.0 0.019 14.7 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 ETS85811.1 - 6.4e-07 29.7 0.0 0.036 14.5 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_14 PF13173.6 ETS85811.1 - 6.4e-07 29.5 0.0 0.0075 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 ETS85811.1 - 8.5e-07 28.5 0.3 0.25 10.6 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_25 PF13481.6 ETS85811.1 - 1e-06 28.5 4.0 0.18 11.3 0.1 4.7 3 2 2 5 5 5 2 AAA domain DUF815 PF05673.13 ETS85811.1 - 1.9e-06 27.3 0.0 0.0053 15.9 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_7 PF12775.7 ETS85811.1 - 2.2e-06 27.3 0.1 0.032 13.7 0.0 2.9 2 2 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 ETS85811.1 - 3.2e-06 27.1 0.1 0.00014 21.8 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_24 PF13479.6 ETS85811.1 - 3.7e-06 26.8 0.0 0.082 12.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.17 ETS85811.1 - 9.1e-06 25.0 0.1 0.052 12.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 ETS85811.1 - 1.8e-05 25.0 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 ETS85811.1 - 2.2e-05 24.2 0.0 0.25 11.0 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 ETS85811.1 - 2.9e-05 24.6 0.0 0.27 11.8 0.0 3.4 2 1 0 2 2 2 2 ABC transporter Bac_DnaA PF00308.18 ETS85811.1 - 4.4e-05 23.4 0.0 0.21 11.4 0.0 3.1 3 0 0 3 3 3 2 Bacterial dnaA protein TsaE PF02367.17 ETS85811.1 - 6.7e-05 22.9 0.0 0.4 10.7 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 ETS85811.1 - 0.00013 21.9 0.1 0.18 11.7 0.0 2.9 3 0 0 3 3 3 1 NACHT domain ResIII PF04851.15 ETS85811.1 - 0.00014 21.9 0.0 0.045 13.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_17 PF13207.6 ETS85811.1 - 0.00022 21.7 0.0 0.59 10.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 ETS85811.1 - 0.00022 21.1 0.0 0.7 9.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 ETS85811.1 - 0.00023 20.7 0.3 0.67 9.4 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 ETS85811.1 - 0.00037 20.4 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 ETS85811.1 - 0.00046 20.0 0.3 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 ETS85811.1 - 0.00058 19.8 0.0 2 8.2 0.0 3.5 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 ETS85811.1 - 0.00098 19.5 0.4 5.5 7.3 0.0 3.6 3 1 1 4 4 3 0 AAA domain DUF2075 PF09848.9 ETS85811.1 - 0.002 17.4 0.0 1.6 7.8 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 ETS85811.1 - 0.0036 17.4 0.0 0.55 10.3 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 ETS85811.1 - 0.0049 16.1 0.0 1.4 8.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.15 ETS85811.1 - 0.0058 16.6 0.4 2.5 8.0 0.0 3.8 4 0 0 4 4 3 1 NTPase Viral_helicase1 PF01443.18 ETS85811.1 - 0.0073 16.1 0.0 0.33 10.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 ETS85811.1 - 0.011 15.0 0.6 7.9 5.7 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin IPT PF01745.16 ETS85811.1 - 0.013 14.9 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UFD1 PF03152.14 ETS85811.1 - 0.027 13.9 0.0 0.25 10.8 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 KAP_NTPase PF07693.14 ETS85811.1 - 0.03 13.6 0.5 1.1 8.4 0.0 3.1 2 2 1 4 4 4 0 KAP family P-loop domain Zot PF05707.12 ETS85811.1 - 0.042 13.5 0.1 2.9 7.5 0.0 3.3 2 2 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_6 PF12774.7 ETS85811.1 - 0.05 12.6 0.1 7.6 5.4 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AFG1_ATPase PF03969.16 ETS85811.1 - 0.055 12.3 0.0 6.8 5.5 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase Cytidylate_kin PF02224.18 ETS85811.1 - 0.065 13.0 0.0 10 5.8 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase Cytidylate_kin2 PF13189.6 ETS85811.1 - 0.066 13.3 0.0 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family ASF1_hist_chap PF04729.13 ETS85812.1 - 3.2e-72 241.5 0.0 4.3e-72 241.1 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Suf PF05843.14 ETS85813.1 - 1.6e-85 287.6 0.7 1.7e-81 274.5 0.0 3.9 4 1 1 5 5 5 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 ETS85813.1 - 0.00075 18.7 2.7 0.0069 15.6 0.9 3.3 3 1 1 4 4 4 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 ETS85813.1 - 0.001 19.7 5.1 0.79 10.7 0.1 6.0 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS85813.1 - 0.0033 17.9 0.0 0.13 12.8 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 ETS85813.1 - 0.014 14.6 0.7 4.1 6.5 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat FemAB PF02388.16 ETS85813.1 - 0.033 13.1 0.1 0.033 13.1 0.1 1.8 2 0 0 2 2 2 0 FemAB family Ndc1_Nup PF09531.10 ETS85813.1 - 0.79 8.3 6.2 1.6 7.4 6.2 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Piwi PF02171.17 ETS85814.1 - 2.2e-74 250.4 1.0 3.1e-74 250.0 0.2 1.6 2 0 0 2 2 2 1 Piwi domain ArgoN PF16486.5 ETS85814.1 - 9e-24 84.7 0.0 2.8e-23 83.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 ETS85814.1 - 9.6e-14 50.8 0.0 2.9e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 ETS85814.1 - 1.7e-08 34.7 0.0 4.4e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 ETS85814.1 - 2.5e-08 34.1 0.0 8.1e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 Mid domain of argonaute PAZ PF02170.22 ETS85814.1 - 3.1e-07 30.3 0.1 6e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 PAZ domain YdaS_antitoxin PF15943.5 ETS85814.1 - 0.14 12.1 0.5 0.6 10.0 0.0 2.2 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT RGS PF00615.19 ETS85815.1 - 0.00034 20.9 0.0 0.0013 19.0 0.0 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF4293 PF14126.6 ETS85815.1 - 2.3 8.5 7.0 1.5 9.1 4.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF2929 PF11151.8 ETS85816.1 - 0.44 10.9 2.0 3.9 7.8 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) DUF2415 PF10313.9 ETS85817.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) SAP18 PF06487.12 ETS85818.1 - 0.051 13.7 0.3 0.064 13.4 0.3 1.3 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) FapA PF03961.13 ETS85818.1 - 0.47 9.0 2.8 0.55 8.8 2.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 ETS85818.1 - 1.8 8.1 11.1 2.3 7.7 11.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit THOC7 PF05615.13 ETS85818.1 - 9.1 6.6 19.2 2.3 8.5 4.2 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 DUF455 PF04305.14 ETS85821.1 - 4.6e-98 327.7 0.0 6.1e-98 327.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 ETS85821.1 - 1e-05 25.4 0.0 2.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ETS85821.1 - 0.00048 20.0 0.0 0.0017 18.2 0.0 2.0 2 1 0 2 2 2 1 Rieske-like [2Fe-2S] domain AMMECR1 PF01871.17 ETS85822.1 - 1.1e-46 158.5 0.0 1.6e-46 158.0 0.0 1.3 1 1 0 1 1 1 1 AMMECR1 Asp PF00026.23 ETS85823.1 - 6.4e-59 199.9 5.9 1.3e-58 198.9 5.9 1.5 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS85823.1 - 1.7e-06 28.4 1.2 1.7e-06 28.4 1.2 3.9 3 2 0 3 3 3 1 Xylanase inhibitor N-terminal Ras PF00071.22 ETS85824.1 - 6.7e-39 133.1 0.0 3.6e-24 85.2 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 ETS85824.1 - 1.7e-11 44.3 0.0 4.1e-11 43.1 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ETS85824.1 - 0.0054 16.8 0.0 0.0094 16.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 ETS85824.1 - 0.011 15.2 0.0 0.047 13.2 0.0 1.9 1 1 0 1 1 1 0 ADP-ribosylation factor family PRK PF00485.18 ETS85824.1 - 0.08 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family adh_short PF00106.25 ETS85825.1 - 6e-45 153.1 0.0 9.7e-45 152.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS85825.1 - 4.7e-34 118.0 0.0 6.2e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS85825.1 - 3.4e-12 46.7 0.0 5.5e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ETS85825.1 - 2.5e-05 23.8 0.0 3.2e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 ETS85825.1 - 6.3e-05 22.6 0.0 0.00015 21.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS85825.1 - 0.00016 21.6 0.1 0.0004 20.3 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_2 PF03446.15 ETS85825.1 - 0.02 15.1 0.0 0.053 13.7 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ETS85825.1 - 0.059 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent YjeF_N PF03853.15 ETS85825.1 - 0.1 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus Eno-Rase_NADH_b PF12242.8 ETS85825.1 - 0.35 10.7 1.7 1.6 8.6 0.0 2.6 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ank_2 PF12796.7 ETS85826.1 - 9e-66 218.5 3.6 1.6e-16 60.6 0.1 6.8 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS85826.1 - 3.1e-44 143.9 2.9 8.9e-06 25.7 0.0 11.5 12 0 0 12 12 12 6 Ankyrin repeat Ank_4 PF13637.6 ETS85826.1 - 5.9e-41 138.3 6.7 7.8e-10 39.1 0.0 8.3 3 2 5 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS85826.1 - 1.4e-39 133.6 11.3 9.1e-06 25.9 0.0 9.8 4 3 6 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 ETS85826.1 - 8.4e-36 120.9 14.3 5.3e-05 23.5 0.1 11.2 11 0 0 11 11 11 6 Ankyrin repeat NACHT PF05729.12 ETS85826.1 - 6.4e-11 42.5 0.0 2.2e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 ETS85826.1 - 0.00014 22.1 0.0 0.00061 20.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS85826.1 - 0.0023 18.3 0.2 0.013 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain SesA PF17107.5 ETS85826.1 - 0.0073 16.5 0.1 0.018 15.2 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_33 PF13671.6 ETS85826.1 - 0.017 15.3 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ETS85826.1 - 0.029 14.8 0.3 0.14 12.6 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DHC_N2 PF08393.13 ETS85826.1 - 0.038 13.1 0.3 0.14 11.2 0.1 1.9 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 2 Torsin PF06309.11 ETS85826.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Torsin adh_short PF00106.25 ETS85827.1 - 2.7e-38 131.4 0.2 3.5e-38 131.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS85827.1 - 4.4e-29 101.7 0.0 5.6e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS85827.1 - 1.1e-05 25.4 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ETS85827.1 - 0.00035 20.1 0.0 0.00043 19.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) APH PF01636.23 ETS85828.1 - 8e-09 35.8 0.0 2e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ETS85828.1 - 0.026 13.8 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1264 PF06884.11 ETS85829.1 - 5.6e-77 257.2 0.2 6.7e-77 256.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) DUF2347 PF09804.9 ETS85830.1 - 5.1e-105 351.1 0.0 1.2e-104 349.8 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 ETS85830.1 - 3.1e-56 190.8 2.8 3.3e-56 190.6 0.2 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4484) SPA PF08616.10 ETS85830.1 - 0.0011 18.9 0.1 0.01 15.8 0.1 2.3 2 1 0 2 2 2 1 Stabilization of polarity axis Avl9 PF09794.9 ETS85830.1 - 0.015 14.0 0.0 0.49 9.0 0.0 2.1 2 0 0 2 2 2 0 Transport protein Avl9 Zn_clus PF00172.18 ETS85831.1 - 0.0012 18.9 2.0 0.0018 18.3 2.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 ETS85832.1 - 1.2e-07 31.7 19.5 0.0003 20.8 4.4 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaJ PF00226.31 ETS85833.1 - 4.5e-16 58.7 2.1 1.2e-15 57.3 2.1 1.8 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 ETS85833.1 - 3.5e-11 42.8 0.0 2e-10 40.2 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain DctQ PF04290.12 ETS85833.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component Glyco_hydro_3_C PF01915.22 ETS85834.1 - 1.3e-50 172.2 0.0 2.2e-50 171.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS85834.1 - 9.4e-42 143.5 0.0 1.9e-41 142.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS85834.1 - 4.2e-16 58.8 0.0 1e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 ETS85834.1 - 6.6e-09 35.7 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Amino_oxidase PF01593.24 ETS85835.1 - 7.6e-36 124.4 0.0 9.9e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ETS85835.1 - 2.4e-08 34.1 0.0 8.3e-08 32.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS85835.1 - 0.0011 18.6 0.0 0.0043 16.7 0.0 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS85835.1 - 0.034 13.4 0.0 0.084 12.1 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS85835.1 - 0.2 10.8 0.0 0.82 8.8 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 ETS85835.1 - 0.21 10.8 0.0 0.39 9.9 0.0 1.5 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 ETS85836.1 - 3e-37 129.0 0.0 3.5e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS85836.1 - 7e-09 35.3 0.2 2.4e-06 26.9 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS85836.1 - 1.7e-06 28.2 0.3 4.5e-06 26.8 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS85836.1 - 3.8e-06 26.4 0.0 3.4e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS85836.1 - 1.4e-05 24.5 0.0 0.00019 20.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS85836.1 - 3e-05 22.9 0.1 5.3e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 ETS85836.1 - 3.8e-05 23.0 0.0 6.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 ETS85836.1 - 4.3e-05 23.0 0.0 7.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ETS85836.1 - 0.00022 20.4 0.1 0.0042 16.2 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ETS85836.1 - 0.00031 20.1 0.1 0.00054 19.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ETS85836.1 - 0.002 18.7 0.0 0.0037 17.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ETS85836.1 - 0.006 17.0 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 ETS85836.1 - 0.01 14.9 0.1 0.016 14.3 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.6 ETS85836.1 - 0.021 14.0 0.1 3.9 6.5 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) ApbA PF02558.16 ETS85836.1 - 0.089 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 ETS85836.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 ETS85837.1 - 9.6e-16 57.6 33.6 9.6e-16 57.6 33.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily CheC PF04509.12 ETS85837.1 - 0.24 11.3 0.8 25 4.9 0.1 2.4 2 0 0 2 2 2 0 CheC-like family NmrA PF05368.13 ETS85838.1 - 2.6e-35 122.1 0.0 3.4e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS85838.1 - 1.3e-24 87.1 0.4 2.4e-24 86.2 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ETS85838.1 - 3.6e-06 26.3 0.2 8.2e-06 25.1 0.2 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 ETS85838.1 - 0.0089 15.5 0.0 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 ETS85838.1 - 0.022 14.2 0.3 0.04 13.4 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 ETS85838.1 - 0.025 14.0 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ETS85838.1 - 0.037 13.0 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 ETS85838.1 - 0.049 13.9 0.2 0.091 13.0 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.17 ETS85838.1 - 0.05 14.2 0.1 0.44 11.2 0.1 2.5 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Aa_trans PF01490.18 ETS85839.1 - 6.2e-16 58.1 12.4 8.7e-16 57.6 12.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2633 PF11119.8 ETS85839.1 - 0.02 14.8 5.1 0.36 10.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) UPF0114 PF03350.16 ETS85839.1 - 2.8 8.1 0.0 2.8 8.1 0.0 3.3 3 1 1 4 4 4 0 Uncharacterized protein family, UPF0114 Peptidase_M20 PF01546.28 ETS85840.1 - 1.3e-21 77.2 1.0 4.8e-21 75.4 1.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ETS85840.1 - 1.1e-20 73.6 0.1 1.8e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ETS85840.1 - 8.9e-05 22.3 0.0 0.00023 20.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 PQ-loop PF04193.14 ETS85841.1 - 1.3e-36 124.2 6.6 3.1e-18 65.3 0.4 2.9 2 1 0 2 2 2 2 PQ loop repeat ATG22 PF11700.8 ETS85841.1 - 0.019 13.6 0.0 0.038 12.6 0.0 1.6 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like NMN_transporter PF04973.12 ETS85841.1 - 1.1 9.1 9.2 2.7 7.9 0.7 3.4 2 1 1 3 3 3 0 Nicotinamide mononucleotide transporter DUF3328 PF11807.8 ETS85843.1 - 2.8e-47 161.4 5.9 3.6e-47 161.0 5.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_3 PF13302.7 ETS85844.1 - 1.2e-21 77.8 0.0 1.6e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SET PF00856.28 ETS85845.1 - 5.2e-06 27.0 0.1 0.00027 21.4 0.1 2.3 1 1 0 1 1 1 1 SET domain SAF PF08666.12 ETS85845.1 - 0.084 13.5 0.1 6.2 7.5 0.0 2.6 3 0 0 3 3 3 0 SAF domain Peptidase_S10 PF00450.22 ETS85846.1 - 4.5e-29 102.1 0.1 3.1e-17 63.1 0.0 3.0 2 1 0 2 2 2 2 Serine carboxypeptidase Transketolase_N PF00456.21 ETS85847.1 - 8.6e-140 465.4 0.0 1.2e-139 465.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ETS85847.1 - 7.4e-35 120.2 0.0 1.7e-34 119.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ETS85847.1 - 5.9e-13 48.8 0.0 1.4e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 ETS85847.1 - 0.00066 19.5 0.7 0.0028 17.5 0.7 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 ETS85847.1 - 0.0037 16.3 0.0 0.0063 15.5 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 ETS85847.1 - 0.15 11.2 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Med10 PF09748.9 ETS85850.1 - 7.2e-47 158.3 0.1 8.3e-47 158.1 0.1 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF4972 PF16342.5 ETS85850.1 - 0.15 11.7 0.1 0.86 9.3 0.1 2.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4972) DUF3877 PF12993.7 ETS85850.1 - 0.19 11.6 0.0 0.25 11.2 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) PAM2 PF07145.15 ETS85851.1 - 0.0096 15.6 0.2 0.024 14.3 0.1 1.8 1 1 0 1 1 1 1 Ataxin-2 C-terminal region HET PF06985.11 ETS85852.1 - 3.4e-26 92.3 0.0 6.2e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.23 ETS85853.1 - 9.2e-16 57.8 4.4 2e-15 56.8 4.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS85853.1 - 2.1e-11 43.7 0.0 5e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Ank_2 PF12796.7 ETS85854.1 - 3.7e-06 27.4 0.3 0.022 15.3 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS85854.1 - 1.6e-05 24.9 1.3 6.4 7.7 0.0 5.0 3 2 2 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 ETS85854.1 - 1.7e-05 25.3 0.2 0.8 10.4 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS85854.1 - 0.00014 22.1 3.3 1.8 9.0 0.2 4.5 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS85854.1 - 0.022 15.2 2.1 17 6.0 0.1 4.0 2 2 2 4 4 4 0 Ankyrin repeat Epimerase PF01370.21 ETS85856.1 - 4.2e-11 42.8 0.1 1.7e-10 40.8 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS85856.1 - 1e-07 32.0 0.0 3.2e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS85856.1 - 2.2e-05 24.1 0.2 4.1e-05 23.2 0.2 1.6 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 ETS85856.1 - 0.002 17.2 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ETS85856.1 - 0.0022 17.2 0.0 0.0032 16.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 ETS85856.1 - 0.0037 16.8 0.3 0.024 14.1 0.1 2.4 3 0 0 3 3 3 1 short chain dehydrogenase NAD_binding_4 PF07993.12 ETS85856.1 - 0.043 13.0 0.2 0.35 10.0 0.2 2.2 1 1 0 1 1 1 0 Male sterility protein GDP_Man_Dehyd PF16363.5 ETS85856.1 - 0.15 11.4 0.0 0.39 10.1 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF423 PF04241.15 ETS85857.1 - 0.032 14.4 0.5 0.18 12.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF423) FMO-like PF00743.19 ETS85858.1 - 5.6e-16 58.1 0.3 4.1e-14 51.9 0.3 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ETS85858.1 - 4e-13 49.4 0.0 1.6e-12 47.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS85858.1 - 3.3e-10 39.7 0.0 1.8e-09 37.3 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS85858.1 - 1.1e-09 38.0 0.0 4.6e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ETS85858.1 - 2.2e-06 27.1 0.0 1.4e-05 24.5 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS85858.1 - 0.00012 21.8 0.0 0.0072 15.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS85858.1 - 0.0003 20.8 0.0 0.00097 19.2 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 ETS85858.1 - 0.017 15.2 0.0 0.18 11.9 0.0 2.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 ETS85858.1 - 0.038 12.7 0.0 0.074 11.7 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 ETS85858.1 - 0.039 14.5 0.0 9.3 6.9 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS85858.1 - 0.067 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Trp_DMAT PF11991.8 ETS85859.1 - 1.6e-91 307.5 0.0 1.8e-91 307.3 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.22 ETS85860.1 - 3.5e-61 207.4 0.0 4.3e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 ETS85861.1 - 2e-09 37.9 7.8 6.2e-08 33.1 7.8 3.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1489 PF07370.11 ETS85861.1 - 0.026 14.3 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) Ins_P5_2-kin PF06090.12 ETS85861.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase APH PF01636.23 ETS85862.1 - 1.8e-12 47.7 0.1 7.4e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 ETS85862.1 - 0.00067 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 ETS85862.1 - 0.023 13.6 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Kdo PF06293.14 ETS85862.1 - 0.052 12.9 0.1 0.16 11.3 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FKBP_N_2 PF18023.1 ETS85862.1 - 0.17 12.0 0.1 0.33 11.1 0.1 1.4 1 0 0 1 1 1 0 BDBT FKBP like N-terminal GMC_oxred_N PF00732.19 ETS85863.1 - 4.9e-64 216.5 0.0 6.9e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS85863.1 - 2e-29 103.0 0.0 5.8e-29 101.5 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ETS85863.1 - 0.00011 21.4 0.1 0.00016 20.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 ETS85863.1 - 0.0018 17.6 0.1 0.0036 16.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 ETS85863.1 - 0.028 13.5 0.0 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 ETS85863.1 - 0.03 13.2 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_8 PF13450.6 ETS85863.1 - 0.03 14.5 0.0 0.072 13.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Fungal_trans PF04082.18 ETS85864.1 - 4e-14 52.3 0.5 7.7e-14 51.4 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS85864.1 - 9e-05 22.5 11.1 0.00016 21.7 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CN_hydrolase PF00795.22 ETS85865.1 - 5.5e-37 127.5 0.0 7.7e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Amidohydro_1 PF01979.20 ETS85866.1 - 2.7e-52 178.2 0.8 3.2e-52 178.0 0.8 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS85866.1 - 1.3e-24 87.5 0.1 5.1e-19 69.1 0.1 2.5 2 1 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 ETS85866.1 - 0.001 18.4 0.1 0.0066 15.8 0.1 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase DisA_N PF02457.16 ETS85866.1 - 0.03 13.9 0.7 0.34 10.5 0.0 2.3 2 0 0 2 2 2 0 DisA bacterial checkpoint controller nucleotide-binding DAO PF01266.24 ETS85867.1 - 1.9e-26 93.5 0.3 2.3e-26 93.2 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS85867.1 - 0.051 12.8 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS85867.1 - 0.055 12.5 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 ETS85867.1 - 0.11 12.8 0.2 0.44 10.8 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Amidohydro_1 PF01979.20 ETS85868.1 - 8.7e-19 68.0 0.0 1.7e-18 67.1 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS85868.1 - 5.5e-12 45.9 0.0 1.6e-10 41.1 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase family DIOX_N PF14226.6 ETS85869.1 - 4.6e-30 104.8 0.0 9.6e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS85869.1 - 5.1e-15 55.8 0.0 1.2e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ETS85870.1 - 1.4e-31 109.7 0.0 2.2e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS85870.1 - 3.4e-18 66.0 0.0 7.2e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sel_put PF04328.13 ETS85870.1 - 1.1 9.3 5.1 1.5 8.9 2.5 2.2 2 0 0 2 2 2 0 Selenoprotein, putative MFS_1 PF07690.16 ETS85871.1 - 1e-31 110.2 20.4 1e-31 110.2 20.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS85871.1 - 8.2e-06 25.3 2.2 8.2e-06 25.3 2.2 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB ADH_zinc_N PF00107.26 ETS85872.1 - 2e-21 76.3 0.7 1.2e-20 73.9 0.3 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS85872.1 - 3.4e-20 71.9 0.2 5.9e-20 71.2 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 ETS85872.1 - 1.1e-05 25.0 0.6 1.7e-05 24.4 0.6 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Leu_Phe_trans PF03588.14 ETS85872.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase DUF4334 PF14232.6 ETS85873.1 - 2.3e-25 88.3 0.2 8.3e-25 86.5 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4334) GXWXG PF14231.6 ETS85873.1 - 1.8e-24 85.6 0.1 2.5e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 GXWXG protein DUF2249 PF10006.9 ETS85873.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) DUF3425 PF11905.8 ETS85874.1 - 1.6e-16 60.4 0.0 3.2e-16 59.4 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) GST_C PF00043.25 ETS85876.1 - 7e-08 32.6 0.0 1.3e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ETS85876.1 - 4.9e-07 30.0 0.0 6.1e-06 26.5 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ETS85876.1 - 5.5e-07 29.9 0.0 9.5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ETS85876.1 - 3e-05 24.1 0.0 5.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ETS85876.1 - 0.00063 20.0 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS85876.1 - 0.0019 18.2 0.1 0.0072 16.3 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Exonuc_VII_L PF02601.15 ETS85877.1 - 0.59 9.7 2.7 0.8 9.2 2.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Macoilin PF09726.9 ETS85877.1 - 1.3 7.5 7.8 1.5 7.3 7.8 1.0 1 0 0 1 1 1 0 Macoilin family DUF4140 PF13600.6 ETS85877.1 - 4 7.9 6.5 70 4.0 6.4 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) PP-binding PF00550.25 ETS85879.1 - 6.9e-12 45.6 0.1 8.8e-12 45.2 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 ETS85879.1 - 6.7e-05 23.0 0.2 8.4e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Acyl-carrier Fer4 PF00037.27 ETS85880.1 - 1.3e-13 50.1 16.5 5.5e-08 32.3 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 ETS85880.1 - 6.2e-13 49.1 10.2 9.9e-13 48.5 10.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 ETS85880.1 - 3.3e-10 40.8 7.5 5.9e-05 23.9 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 ETS85880.1 - 1.3e-09 38.0 31.3 6.7e-06 26.1 12.3 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 ETS85880.1 - 5.8e-09 35.9 21.0 1.4e-06 28.3 12.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 ETS85880.1 - 2e-08 34.3 9.2 3.6e-08 33.4 9.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 ETS85880.1 - 1.2e-06 28.8 19.7 0.0004 20.8 11.7 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 ETS85880.1 - 1.3e-06 28.3 17.1 0.00036 20.5 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 ETS85880.1 - 3.8e-06 26.7 11.8 0.0088 16.1 1.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 ETS85880.1 - 6.5e-06 26.2 11.2 0.00024 21.4 1.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 ETS85880.1 - 0.0001 22.8 10.5 0.02 15.4 12.1 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 ETS85880.1 - 0.0087 16.3 5.7 0.29 11.4 0.3 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 ETS85880.1 - 0.046 13.9 8.7 0.95 9.7 1.4 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 ETS85880.1 - 0.047 14.2 14.7 0.67 10.5 4.3 2.7 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I ETF_QO PF05187.13 ETS85880.1 - 0.087 13.0 5.8 0.4 10.8 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.7 ETS85880.1 - 0.2 12.7 15.5 0.38 11.8 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 ETS85880.1 - 0.42 11.5 11.6 3.7 8.4 2.3 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Cellulase PF00150.18 ETS85881.1 - 4.8e-08 32.8 0.1 1.2e-07 31.5 0.1 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.16 ETS85883.1 - 2.4e-30 105.7 25.0 2.4e-30 105.7 25.0 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS85883.1 - 8.9e-12 44.6 7.3 8.9e-12 44.6 7.3 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 ETS85883.1 - 0.0056 15.2 4.2 0.01 14.3 4.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_3_C PF01915.22 ETS85884.1 - 1.4e-49 168.8 0.0 2.1e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS85884.1 - 9.6e-32 110.6 0.0 2.4e-31 109.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS85884.1 - 2.9e-24 85.0 0.0 6.7e-24 83.8 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain TraW_N PF12477.8 ETS85884.1 - 0.019 14.9 1.4 0.03 14.3 0.1 2.1 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal Peptidase_M28 PF04389.17 ETS85885.1 - 1.8e-22 80.0 0.0 2.8e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ETS85885.1 - 9e-07 28.8 0.1 2.8e-06 27.2 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Cnl2_NKP2 PF09447.10 ETS85885.1 - 0.021 15.0 0.4 0.068 13.3 0.1 1.9 2 0 0 2 2 2 0 Cnl2/NKP2 family protein FAA_hydrolase PF01557.18 ETS85886.1 - 1.2e-54 185.2 0.0 1.6e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.18 ETS85887.1 - 4.6e-18 65.2 0.3 9.5e-18 64.2 0.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 ETS85888.1 - 1.9e-19 70.1 0.0 7.3e-19 68.2 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS85888.1 - 5.3e-08 32.8 1.6 0.0043 16.7 2.6 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS85888.1 - 3.3e-05 23.2 1.8 5.1e-05 22.5 1.8 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ETS85888.1 - 0.00041 19.2 0.7 0.00066 18.5 0.7 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 ETS85888.1 - 0.00045 20.4 2.2 0.00077 19.7 1.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS85888.1 - 0.00046 19.5 0.8 0.0013 18.0 0.6 1.7 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS85888.1 - 0.0005 20.6 0.1 0.0068 16.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ETS85888.1 - 0.0011 18.1 0.0 0.011 14.8 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase FAD_oxidored PF12831.7 ETS85888.1 - 0.0013 18.1 1.1 0.002 17.5 1.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ETS85888.1 - 0.0025 17.0 1.0 0.0036 16.4 1.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 ETS85888.1 - 0.048 13.5 0.2 0.081 12.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 ETS85888.1 - 0.064 12.1 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 ETS85888.1 - 0.084 12.1 0.2 0.14 11.4 0.2 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 ETS85888.1 - 0.15 11.3 0.4 0.26 10.5 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Abhydrolase_3 PF07859.13 ETS85889.1 - 8e-15 55.3 0.0 2.9e-09 37.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS85889.1 - 1.3e-10 41.1 0.0 6.7e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ETS85889.1 - 1.3e-05 25.1 0.0 0.021 14.7 0.0 2.6 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase COesterase PF00135.28 ETS85889.1 - 0.0003 19.8 0.0 0.00055 18.9 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 ETS85889.1 - 0.02 14.2 0.0 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 ETS85889.1 - 0.027 13.4 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.18 ETS85889.1 - 0.054 13.0 0.0 0.15 11.5 0.0 1.7 3 0 0 3 3 3 0 Dienelactone hydrolase family Esterase PF00756.20 ETS85889.1 - 0.062 12.9 0.0 0.22 11.1 0.0 1.7 1 1 0 1 1 1 0 Putative esterase LIP PF03583.14 ETS85889.1 - 0.063 12.6 0.0 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 Secretory lipase Peptidase_S15 PF02129.18 ETS85889.1 - 0.085 12.4 0.0 5.6 6.5 0.0 2.6 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Cupin_2 PF07883.11 ETS85890.1 - 2.8e-12 46.2 0.5 2.6e-09 36.7 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 ETS85890.1 - 0.00094 18.8 0.1 0.18 11.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 ETS85890.1 - 0.025 14.5 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain Ppnp PF06865.11 ETS85890.1 - 0.062 13.7 0.0 0.38 11.2 0.0 2.3 3 0 0 3 3 3 0 Pyrimidine/purine nucleoside phosphorylase Cupin_4 PF08007.12 ETS85890.1 - 0.13 11.7 0.4 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Cupin superfamily protein TPR_19 PF14559.6 ETS85891.1 - 2.2e-06 28.0 12.3 0.0028 18.1 0.1 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 ETS85891.1 - 6.5e-06 25.9 26.4 0.00031 20.6 0.1 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 ETS85891.1 - 6.2e-05 22.7 19.1 0.0007 19.3 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 ETS85891.1 - 0.00075 19.4 7.7 0.37 10.9 0.1 4.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 ETS85891.1 - 0.001 18.7 15.4 0.09 12.5 0.1 4.8 5 0 0 5 5 5 2 TPR repeat TPR_14 PF13428.6 ETS85891.1 - 0.0012 19.5 14.4 0.73 10.8 0.2 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 ETS85891.1 - 0.0017 19.0 12.7 9.3 7.0 0.2 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 ETS85891.1 - 0.0029 17.7 13.4 0.11 12.8 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 ETS85891.1 - 0.019 15.2 16.8 0.48 10.7 2.0 5.7 5 1 2 7 7 7 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 ETS85891.1 - 0.098 12.7 0.0 8.8 6.4 0.0 3.0 2 1 0 2 2 2 0 Putative TPR-like repeat TPR_17 PF13431.6 ETS85891.1 - 0.1 13.0 2.7 61 4.3 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 ETS85891.1 - 0.16 11.9 5.2 18 5.4 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 ETS85891.1 - 0.79 9.9 5.1 11 6.3 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 ETS85891.1 - 3.6 8.5 8.6 13 6.8 0.4 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TauD PF02668.16 ETS85892.1 - 1.2e-30 107.3 1.8 2e-30 106.5 1.8 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family dCMP_cyt_deam_1 PF00383.23 ETS85893.1 - 8.3e-09 35.2 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ETS85893.1 - 1.5e-05 24.8 0.1 0.00036 20.3 0.1 2.1 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 ETS85893.1 - 0.06 13.4 2.0 0.2 11.7 2.0 1.7 1 1 0 1 1 1 0 Bd3614-like deaminase GLEYA PF10528.9 ETS85894.1 - 1.7e-17 63.6 0.7 4.2e-17 62.4 0.7 1.6 1 0 0 1 1 1 1 GLEYA domain Peptidase_S9 PF00326.21 ETS85895.1 - 3.2e-12 46.4 0.0 4.4e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ETS85895.1 - 0.00019 21.4 0.2 0.00029 20.8 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 ETS85895.1 - 0.00038 20.1 0.0 0.00064 19.3 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 ETS85895.1 - 0.01 15.1 0.1 0.56 9.4 0.0 2.1 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 ETS85895.1 - 0.17 10.7 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase DIOX_N PF14226.6 ETS85896.1 - 1.5e-18 67.6 0.0 3.3e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS85896.1 - 2.6e-16 59.9 0.0 5.2e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NdhN PF11909.8 ETS85896.1 - 0.067 12.9 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N FAD_binding_4 PF01565.23 ETS85897.1 - 3.8e-29 101.2 1.2 6.4e-29 100.5 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS85897.1 - 0.046 13.8 0.3 0.24 11.5 0.1 2.1 2 0 0 2 2 2 0 Berberine and berberine like DsbC_N PF10411.9 ETS85897.1 - 0.16 11.4 0.2 0.87 9.1 0.1 2.2 3 0 0 3 3 3 0 Disulfide bond isomerase protein N-terminus Transp_cyt_pur PF02133.15 ETS85899.1 - 7.5e-91 305.1 36.8 8.9e-91 304.8 36.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cep3 PF16846.5 ETS85900.1 - 0.014 13.9 0.0 0.024 13.2 0.0 1.3 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Fungal_trans PF04082.18 ETS85900.1 - 0.015 14.4 1.9 0.026 13.5 1.9 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Abhydrolase_1 PF00561.20 ETS85901.1 - 1.1e-26 94.1 0.2 1.5e-23 83.7 0.3 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS85901.1 - 2.8e-21 75.9 0.0 3.8e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS85901.1 - 4.3e-19 70.0 0.8 5.2e-19 69.7 0.8 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 ETS85901.1 - 2.1e-09 37.5 0.1 2.8e-06 27.3 0.1 2.3 1 1 1 2 2 2 2 Serine hydrolase Thioesterase PF00975.20 ETS85901.1 - 3.4e-09 37.1 0.0 9.6e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 ETS85901.1 - 2.7e-07 29.6 0.0 3e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Ndr family DUF1057 PF06342.12 ETS85901.1 - 0.00012 21.3 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_2 PF02230.16 ETS85901.1 - 0.00033 20.5 0.0 0.052 13.3 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 ETS85901.1 - 0.00049 19.9 0.0 0.00092 19.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 ETS85901.1 - 0.0021 17.6 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF1749 PF08538.10 ETS85901.1 - 0.0036 16.4 0.0 0.0045 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Esterase PF00756.20 ETS85901.1 - 0.0046 16.6 0.2 0.032 13.9 0.2 2.0 1 1 0 1 1 1 1 Putative esterase LCAT PF02450.15 ETS85901.1 - 0.0064 15.7 0.0 0.0094 15.2 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase FSH1 PF03959.13 ETS85901.1 - 0.0095 15.6 0.0 0.41 10.3 0.0 2.7 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 ETS85901.1 - 0.013 15.4 0.2 0.017 15.0 0.2 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 ETS85901.1 - 0.019 13.5 0.2 2 6.8 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Lipase_3 PF01764.25 ETS85901.1 - 0.035 14.0 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF3530 PF12048.8 ETS85901.1 - 0.035 13.5 0.1 0.049 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DLH PF01738.18 ETS85901.1 - 0.048 13.2 0.0 0.12 11.9 0.0 1.7 1 1 1 2 2 2 0 Dienelactone hydrolase family DUF900 PF05990.12 ETS85901.1 - 0.087 12.3 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 ETS85901.1 - 0.12 12.0 0.0 0.33 10.6 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein TauD PF02668.16 ETS85902.1 - 4.3e-36 125.1 0.7 5.5e-36 124.7 0.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Barwin PF00967.17 ETS85903.1 - 0.00064 19.6 0.2 0.00076 19.3 0.2 1.2 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 ETS85903.1 - 0.055 13.7 0.0 0.12 12.7 0.0 1.6 1 1 0 1 1 1 0 Lytic transglycolase HET PF06985.11 ETS85904.1 - 1e-33 116.7 0.3 1.5e-33 116.2 0.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clusterin PF01093.17 ETS85904.1 - 0.049 12.7 0.1 0.91 8.5 0.1 2.2 2 0 0 2 2 2 0 Clusterin Transp_cyt_pur PF02133.15 ETS85905.1 - 2e-90 303.7 38.7 2.4e-90 303.5 38.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.12 ETS85906.1 - 2.3e-125 418.0 0.6 3.9e-125 417.3 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 ETS85906.1 - 8.5e-33 113.5 4.2 1.3e-29 103.2 0.0 3.9 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 ETS85906.1 - 1e-32 113.6 7.5 3.1e-28 98.9 1.2 3.3 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase StbA PF06406.11 ETS85906.1 - 0.00011 21.5 0.4 0.11 11.7 0.1 2.5 2 0 0 2 2 2 2 StbA protein BcrAD_BadFG PF01869.20 ETS85906.1 - 0.00023 20.8 10.5 0.00025 20.6 0.1 3.8 4 1 1 5 5 5 1 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 ETS85906.1 - 0.0018 17.8 0.0 0.0057 16.2 0.0 1.9 1 0 0 1 1 1 1 ROK family MutL PF13941.6 ETS85906.1 - 0.0024 16.6 2.5 0.012 14.2 0.1 2.9 3 0 0 3 3 3 1 MutL protein FtsA PF14450.6 ETS85906.1 - 0.024 15.0 1.4 11 6.5 0.0 3.1 2 2 0 2 2 2 0 Cell division protein FtsA Pyr_redox_3 PF13738.6 ETS85907.1 - 2.1e-19 69.9 0.0 1.6e-18 67.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ETS85907.1 - 8.8e-15 54.1 0.0 7.9e-13 47.7 0.0 2.6 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ETS85907.1 - 5.9e-13 48.7 0.1 3.7e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS85907.1 - 1.7e-12 47.2 0.0 6.4e-10 38.7 0.0 2.5 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ETS85907.1 - 1.2e-05 25.5 0.0 3.5e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS85907.1 - 1.5e-05 24.8 0.1 0.0075 15.9 0.1 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 ETS85907.1 - 0.00014 21.2 0.0 0.00034 19.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 ETS85907.1 - 0.00028 20.9 0.1 0.015 15.3 0.0 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 ETS85907.1 - 0.0024 16.6 0.0 0.58 8.8 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 ETS85907.1 - 0.017 15.6 0.6 5.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS85907.1 - 0.04 13.0 0.1 0.072 12.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Mqo PF06039.15 ETS85907.1 - 0.045 12.3 0.0 2.5 6.5 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.12 ETS85907.1 - 0.21 10.6 0.1 1.2 8.1 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein adh_short_C2 PF13561.6 ETS85908.1 - 2.7e-59 200.6 0.1 3.1e-59 200.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS85908.1 - 7.9e-47 159.2 0.1 1e-46 158.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS85908.1 - 3.6e-17 62.8 0.0 6e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 ETS85908.1 - 0.0019 17.3 0.1 0.004 16.2 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family HATPase_c PF02518.26 ETS85908.1 - 0.0052 17.3 0.0 0.071 13.6 0.0 2.5 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase adh_short_C2 PF13561.6 ETS85909.1 - 1.2e-57 195.1 6.5 9.2e-56 189.0 6.5 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS85909.1 - 7.6e-43 146.2 3.6 5.6e-41 140.2 3.6 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS85909.1 - 1.1e-09 38.5 2.2 4.8e-09 36.4 2.2 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS85909.1 - 0.00023 20.7 0.3 0.0012 18.4 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ETS85909.1 - 0.0091 15.2 0.1 0.019 14.1 0.1 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Dehydrin PF00257.19 ETS85909.1 - 0.17 12.5 0.2 0.33 11.5 0.2 1.4 1 0 0 1 1 1 0 Dehydrin CAP PF00188.26 ETS85910.1 - 3.9e-17 63.3 4.2 6.2e-17 62.6 4.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family WD40 PF00400.32 ETS85911.1 - 1e-08 35.6 6.3 0.2 12.6 0.4 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat PPR_2 PF13041.6 ETS85912.1 - 8.2e-05 22.7 0.0 0.00021 21.4 0.0 1.7 1 0 0 1 1 1 1 PPR repeat family DUF4245 PF14030.6 ETS85912.1 - 0.12 12.4 0.2 0.28 11.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) MFS_1 PF07690.16 ETS85914.1 - 4.6e-46 157.4 30.9 4.6e-46 157.4 30.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS85914.1 - 1.1e-09 37.7 9.5 1.1e-09 37.7 9.5 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ETS85914.1 - 8.3e-08 31.1 2.8 1.6e-07 30.2 2.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 ETS85914.1 - 9.2e-05 21.0 1.2 9.2e-05 21.0 1.2 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.7 ETS85914.1 - 0.0065 15.4 1.6 0.0065 15.4 1.6 3.3 2 2 0 3 3 3 1 MFS_1 like family DUF3054 PF11255.8 ETS85914.1 - 0.66 10.5 12.2 0.25 11.9 7.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3054) Transp_cyt_pur PF02133.15 ETS85915.1 - 2.2e-36 125.6 37.1 2.1e-35 122.4 37.1 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin LIP PF03583.14 ETS85915.1 - 0.13 11.6 0.4 0.23 10.7 0.4 1.3 1 0 0 1 1 1 0 Secretory lipase HET PF06985.11 ETS85916.1 - 1.5e-21 77.3 0.0 9.9e-21 74.6 0.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) KR PF08659.10 ETS85917.1 - 2.7e-55 187.1 0.0 5.8e-55 186.0 0.0 1.6 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 ETS85917.1 - 1e-13 51.4 0.1 1.5e-12 47.6 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS85917.1 - 6.7e-13 49.8 0.0 2.2e-12 48.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 ETS85917.1 - 4.7e-10 39.3 0.4 2.2e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase ADH_N PF08240.12 ETS85917.1 - 3.2e-07 30.2 0.8 6.8e-07 29.1 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 ETS85917.1 - 6.8e-05 22.5 0.1 0.00018 21.2 0.1 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 ETS85917.1 - 0.027 14.8 0.0 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 Phosphopantetheine attachment site Isochorismatase PF00857.20 ETS85918.1 - 5.7e-27 95.0 0.0 7.3e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF3292 PF11696.8 ETS85919.1 - 0 1024.5 0.0 0 1024.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) PRT_C PF08372.10 ETS85919.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal PMI_typeI PF01238.21 ETS85920.1 - 3e-71 240.6 0.1 3.8e-70 237.0 0.1 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 ETS85920.1 - 3.3e-06 26.7 0.6 0.0013 18.4 0.2 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 ETS85920.1 - 0.0053 16.7 0.1 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.12 ETS85920.1 - 0.0064 16.2 0.8 0.24 11.1 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Sugar_tr PF00083.24 ETS85921.1 - 3.5e-93 312.9 18.9 4.2e-93 312.7 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS85921.1 - 7.4e-31 107.4 18.6 1e-30 106.9 18.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 ETS85922.1 - 1.2e-08 34.4 0.2 1.8e-07 30.5 0.2 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_2_C PF02836.17 ETS85923.1 - 3.1e-111 371.3 0.0 4.1e-111 370.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 ETS85923.1 - 2.2e-67 227.2 0.0 3.9e-67 226.4 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 ETS85923.1 - 7.6e-48 162.6 0.2 1.8e-47 161.4 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 ETS85923.1 - 4e-19 69.3 0.5 4e-19 69.3 0.5 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 DUF4981 PF16353.5 ETS85923.1 - 3.7e-14 53.0 0.7 4.4e-13 49.5 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) BetaGal_dom4_5 PF13364.6 ETS85923.1 - 0.00035 21.1 0.0 0.0013 19.3 0.0 1.9 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Glyco_hydro_42 PF02449.15 ETS85923.1 - 0.044 13.1 0.1 0.095 12.0 0.1 1.5 1 0 0 1 1 1 0 Beta-galactosidase Hydrolase_3 PF08282.12 ETS85924.1 - 2.7e-13 50.3 0.0 1e-11 45.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PMM PF03332.13 ETS85924.1 - 1.5e-11 44.5 0.0 1.8e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase S6PP PF05116.13 ETS85924.1 - 0.00039 20.0 0.0 0.036 13.6 0.0 2.2 1 1 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 ETS85924.1 - 0.007 16.7 0.0 0.11 12.8 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ETS85924.1 - 0.009 16.1 0.0 0.055 13.6 0.0 2.1 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 ETS85925.1 - 1.8e-48 165.3 37.9 1.2e-46 159.3 39.5 2.3 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS85925.1 - 1.6e-21 76.4 18.6 1.6e-21 76.4 17.9 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS85925.1 - 8.9e-16 57.8 26.1 9.9e-16 57.6 10.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 ETS85925.1 - 0.001 18.1 3.4 0.001 18.1 3.4 2.4 2 0 0 2 2 2 1 MFS_1 like family OATP PF03137.20 ETS85925.1 - 0.2 9.9 12.7 1.2 7.3 10.6 2.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family peroxidase PF00141.23 ETS85926.1 - 1.3e-27 97.0 5.5 3e-27 95.8 5.5 1.5 1 1 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 ETS85926.1 - 7e-08 32.3 0.0 2e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Fungal peroxidase extension region NIF PF03031.18 ETS85927.1 - 5.4e-27 94.5 0.1 1.7e-26 92.9 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 ETS85927.1 - 4.5e-07 29.7 0.0 8.3e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 ETS85927.1 - 1e-06 29.0 0.0 2.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl_2 PF13533.6 ETS85927.1 - 0.00058 19.6 0.0 0.0021 17.8 0.0 1.9 1 0 0 1 1 1 1 Biotin-lipoyl like BRCT_2 PF16589.5 ETS85927.1 - 0.0044 17.4 0.0 0.0094 16.3 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Biotin_lipoyl PF00364.22 ETS85927.1 - 0.039 13.8 0.0 0.96 9.3 0.0 2.5 2 0 0 2 2 2 0 Biotin-requiring enzyme HlyD_3 PF13437.6 ETS85927.1 - 0.087 13.5 0.0 0.46 11.2 0.0 2.2 2 0 0 2 2 2 0 HlyD family secretion protein GRIM-19 PF06212.12 ETS85928.1 - 5.8e-10 39.2 0.3 1.4e-09 38.0 0.3 1.6 1 1 0 1 1 1 1 GRIM-19 protein GRAM PF02893.20 ETS85931.1 - 3.7e-31 107.3 2.2 1.5e-17 63.5 0.1 3.5 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 ETS85931.1 - 4.1e-29 101.4 0.0 1.2e-28 99.9 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 ETS85931.1 - 1.3e-13 51.3 0.0 4.1e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 ETS85931.1 - 3e-05 24.4 1.2 0.00037 20.9 1.2 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 ETS85931.1 - 3.5e-05 24.0 0.1 9.7e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.18 ETS85931.1 - 0.0013 17.6 0.0 0.0026 16.6 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_3 PF14593.6 ETS85931.1 - 0.0053 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 ETS85931.1 - 0.09 13.1 0.0 0.71 10.2 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain PH_2 PF08458.10 ETS85931.1 - 0.17 12.3 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Ribosomal_L27A PF00828.19 ETS85932.1 - 1.9e-21 77.1 0.0 3e-21 76.4 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF5026 PF16429.5 ETS85932.1 - 0.41 10.8 1.6 0.93 9.6 1.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5026) Helicase_C_2 PF13307.6 ETS85933.1 - 3.6e-59 199.8 0.0 7.9e-59 198.7 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 ETS85933.1 - 1.6e-46 158.2 0.0 2.4e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 ETS85933.1 - 0.00088 19.3 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 ETS85933.1 - 0.03 14.1 0.1 0.83 9.4 0.0 2.4 2 1 0 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.16 ETS85933.1 - 0.16 11.4 0.1 3.4 7.1 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein PP2C PF00481.21 ETS85934.1 - 2.6e-27 96.1 0.0 1.8e-21 76.9 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C ABM PF03992.16 ETS85935.1 - 0.00036 20.6 0.9 1.4 9.0 0.2 3.0 2 1 1 3 3 3 2 Antibiotic biosynthesis monooxygenase PqqD PF05402.12 ETS85935.1 - 0.16 12.3 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) zf_CCCH_4 PF18345.1 ETS85936.1 - 0.014 15.4 0.4 0.027 14.5 0.4 1.5 1 0 0 1 1 1 0 Zinc finger domain DUF4096 PF13340.6 ETS85936.1 - 0.07 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) zf-CCCH_4 PF18044.1 ETS85936.1 - 0.076 12.8 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger Asn_synthase PF00733.21 ETS85937.1 - 4.5e-67 227.2 0.0 7.1e-67 226.6 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 ETS85937.1 - 2.1e-33 114.9 0.0 3.7e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ETS85937.1 - 1.1e-29 103.4 0.0 2e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 ETS85937.1 - 4.2e-08 32.9 0.0 9.4e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 ETS85937.1 - 0.15 11.2 0.0 0.32 10.1 0.0 1.5 1 0 0 1 1 1 0 NAD synthase TPR_19 PF14559.6 ETS85938.1 - 0.0016 18.9 1.7 0.45 11.1 0.1 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ETS85938.1 - 0.0031 17.8 0.6 1.6 9.1 0.1 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 ETS85938.1 - 0.004 17.0 5.9 0.18 11.8 0.5 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ETS85938.1 - 0.0099 15.9 3.2 0.43 10.8 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 ETS85938.1 - 0.01 15.8 0.1 5.6 7.2 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 ETS85938.1 - 0.065 13.5 0.3 0.52 10.7 0.0 2.5 3 0 0 3 3 3 0 PPR repeat TPR_4 PF07721.14 ETS85938.1 - 0.076 13.7 6.2 2.5 9.0 0.5 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 ETS85938.1 - 0.076 13.7 4.2 1.5 9.5 0.5 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 ETS85938.1 - 0.092 13.6 4.7 6 8.0 0.4 3.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 ETS85938.1 - 0.14 12.5 0.2 5.1 7.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PNGaseA PF12222.8 ETS85939.1 - 8.6e-148 492.8 4.6 1.1e-147 492.4 4.6 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Ribo_biogen_C PF04034.13 ETS85940.1 - 2.9e-50 169.2 0.1 4.1e-50 168.8 0.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 ETS85940.1 - 4.5e-11 42.4 1.8 9.9e-11 41.3 1.8 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI BDHCT_assoc PF16204.5 ETS85940.1 - 7.2 6.2 10.2 0.82 9.3 4.4 2.3 2 1 1 3 3 3 0 BDHCT-box associated domain on Bloom syndrome protein VHS PF00790.19 ETS85941.1 - 4.5e-45 153.0 0.0 2.1e-44 150.8 0.0 2.1 3 0 0 3 3 3 1 VHS domain GAT PF03127.14 ETS85941.1 - 2.8e-18 66.0 0.6 1.1e-17 64.0 0.1 2.3 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.20 ETS85941.1 - 8.9e-18 64.6 0.0 2.4e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 ETS85941.1 - 2.2e-07 30.4 0.1 7.4e-07 28.7 0.1 1.9 1 0 0 1 1 1 1 GGA N-GAT domain GTP_EFTU PF00009.27 ETS85942.1 - 1.3e-33 116.2 4.0 4.4e-32 111.2 4.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 ETS85942.1 - 1.6e-27 95.7 0.2 4e-27 94.4 0.2 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 ETS85942.1 - 3.7e-10 39.9 0.1 7.8e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETS85942.1 - 5.1e-06 26.5 1.4 0.00024 21.0 0.0 2.3 1 1 1 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 ETS85942.1 - 3.2e-05 23.5 0.1 8.6e-05 22.1 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU_D2 PF03144.25 ETS85942.1 - 5.2e-05 23.6 0.5 0.57 10.6 0.0 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 Arf PF00025.21 ETS85942.1 - 0.00029 20.4 0.0 0.00061 19.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family IF2_N PF04760.15 ETS85942.1 - 0.00045 20.0 0.0 0.00094 19.0 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region SRPRB PF09439.10 ETS85942.1 - 0.0016 17.9 0.2 0.0046 16.4 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Roc PF08477.13 ETS85942.1 - 0.0046 17.2 0.0 0.0085 16.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 ETS85942.1 - 0.014 15.1 0.1 0.038 13.7 0.1 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 ETS85942.1 - 0.019 14.0 0.7 0.039 12.9 0.7 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 ETS85942.1 - 0.058 13.9 2.7 4.5 7.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain MMR_HSR1_Xtn PF16897.5 ETS85942.1 - 0.061 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain GTP_EFTU_D4 PF14578.6 ETS85942.1 - 0.1 12.5 2.9 0.97 9.4 0.3 2.8 3 0 0 3 3 3 0 Elongation factor Tu domain 4 Dynamin_N PF00350.23 ETS85942.1 - 1 9.4 3.1 21 5.1 0.0 3.5 3 1 1 4 4 4 0 Dynamin family PP28 PF10252.9 ETS85944.1 - 3.1e-28 98.0 17.8 3.1e-28 98.0 17.8 3.1 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 HET PF06985.11 ETS85945.1 - 3.6e-35 121.5 0.2 7.7e-35 120.4 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 ETS85945.1 - 3.4e-31 107.7 0.7 2.1e-10 41.0 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS85945.1 - 1.7e-22 79.5 0.4 1e-07 32.3 0.0 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS85945.1 - 2.4e-17 61.2 1.2 0.01 16.3 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 ETS85945.1 - 4.7e-14 52.1 2.4 3.3e-05 24.1 0.2 6.5 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 ETS85945.1 - 1.5e-13 50.7 3.7 6.3e-09 35.9 0.1 4.8 2 2 3 5 5 5 3 Ankyrin repeats (many copies) DUF3654 PF12376.8 ETS85945.1 - 0.16 12.2 0.2 0.4 10.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) adh_short PF00106.25 ETS85946.1 - 1.8e-15 56.9 0.0 2.5e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS85946.1 - 3.4e-07 30.3 0.1 4.5e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ETS85946.1 - 2.7e-06 27.1 0.0 3.6e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ETS85946.1 - 0.0029 17.1 0.2 0.0035 16.8 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS85946.1 - 0.0044 16.9 0.6 0.0052 16.7 0.6 1.3 1 1 0 1 1 1 1 NAD(P)H-binding FAD_binding_4 PF01565.23 ETS85947.1 - 2.8e-16 59.5 2.8 7.5e-16 58.1 2.8 1.7 1 1 0 1 1 1 1 FAD binding domain Ank_2 PF12796.7 ETS85948.1 - 6.2e-34 116.4 7.6 2e-06 28.3 0.1 10.9 5 4 4 11 11 11 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS85948.1 - 2.6e-17 62.9 12.9 0.0041 17.7 0.0 11.3 8 3 5 13 13 13 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS85948.1 - 4.3e-17 60.5 15.5 0.62 10.8 0.0 14.6 16 0 0 16 16 16 5 Ankyrin repeat Ank_5 PF13857.6 ETS85948.1 - 1.4e-09 38.0 1.6 0.25 11.7 0.0 6.7 4 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS85948.1 - 1.1e-06 28.9 14.0 2.7 8.6 0.4 9.6 10 1 1 11 11 11 1 Ankyrin repeat Phosphonate-bd PF12974.7 ETS85949.1 - 3.3e-17 62.9 0.0 3.9e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 ETS85949.1 - 0.056 13.4 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 NMT1/THI5 like Cnd1_N PF12922.7 ETS85951.1 - 2.6e-58 196.5 0.1 2.6e-58 196.5 0.1 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 ETS85951.1 - 3.6e-49 166.9 1.3 3.5e-43 147.5 0.3 3.2 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ETS85951.1 - 6.4e-10 38.4 2.4 0.044 14.0 0.0 6.2 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 ETS85951.1 - 3.8e-09 36.8 2.1 0.00024 21.4 0.0 4.5 4 1 0 4 4 3 2 HEAT repeats RTP1_C1 PF10363.9 ETS85951.1 - 1.4e-05 25.3 0.3 0.03 14.5 0.0 3.3 2 1 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 ETS85951.1 - 1.7e-05 25.2 4.6 0.053 14.1 0.0 5.7 5 0 0 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.20 ETS85951.1 - 4.3e-05 22.3 6.2 0.004 15.8 0.4 2.9 3 0 0 3 3 3 2 Adaptin N terminal region Cnd3 PF12719.7 ETS85951.1 - 0.039 13.2 4.3 0.063 12.5 0.4 2.8 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain CdvA PF18822.1 ETS85951.1 - 0.04 13.7 0.2 2.9 7.7 0.1 2.9 1 1 1 2 2 2 0 CdvA-like coiled-coil domain VHS PF00790.19 ETS85951.1 - 0.067 13.0 0.2 3 7.7 0.0 2.7 2 0 0 2 2 2 0 VHS domain DUF573 PF04504.14 ETS85951.1 - 0.8 10.4 4.1 0.59 10.8 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF573 Pkinase PF00069.25 ETS85952.1 - 1.6e-46 158.8 0.0 4.6e-43 147.5 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS85952.1 - 1.3e-13 50.9 0.0 6.4e-08 32.2 0.0 3.4 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.23 ETS85952.1 - 2.6e-05 24.3 1.4 0.0094 15.9 0.0 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ETS85952.1 - 5.4e-05 22.1 0.1 0.00075 18.4 0.0 2.4 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 ETS85952.1 - 8.4e-05 22.0 0.0 0.2 11.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 ETS85952.1 - 0.059 13.0 0.1 1.2 8.7 0.0 2.5 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ETS85952.1 - 0.069 12.5 0.1 0.25 10.7 0.0 2.0 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family SDA1 PF05285.12 ETS85952.1 - 0.17 11.2 11.7 0.25 10.8 11.7 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 ETS85952.1 - 7.3 4.8 11.4 9.9 4.3 11.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4820 PF16091.5 ETS85952.1 - 9.3 5.5 8.7 16 4.7 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF2235 PF09994.9 ETS85953.1 - 8.2e-83 278.1 0.0 1.1e-82 277.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DAO PF01266.24 ETS85954.1 - 1.1e-28 100.9 0.0 1.4e-28 100.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS85954.1 - 3e-05 23.4 0.0 0.0093 15.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS85954.1 - 8.3e-05 22.7 0.0 0.00021 21.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 ETS85954.1 - 0.00089 18.7 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 ThiF family Pyr_redox PF00070.27 ETS85954.1 - 0.003 18.1 0.0 0.024 15.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS85954.1 - 0.0036 17.3 0.1 1.8 8.5 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ETS85954.1 - 0.075 12.3 0.0 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain HET PF06985.11 ETS85955.1 - 1.4e-29 103.3 0.0 2.2e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BcrAD_BadFG PF01869.20 ETS85957.1 - 0.0094 15.5 0.0 0.47 9.9 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FAD_binding_3 PF01494.19 ETS85958.1 - 1.4e-20 73.9 0.0 3.8e-20 72.4 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ETS85958.1 - 0.00045 20.4 0.1 0.0011 19.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 ETS85958.1 - 0.0011 18.1 0.0 0.54 9.3 0.0 2.3 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_2 PF07992.14 ETS85958.1 - 0.0052 16.1 0.1 0.014 14.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS85958.1 - 0.0053 16.4 0.1 0.013 15.1 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS85958.1 - 0.0083 15.4 0.1 0.074 12.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS85958.1 - 0.04 13.0 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.23 ETS85958.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.27 ETS85958.1 - 0.089 13.4 0.1 0.27 11.8 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS85958.1 - 0.17 10.5 0.1 0.5 9.0 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Pox_A9 PF04835.12 ETS85959.1 - 2.7 8.2 14.0 0.92 9.7 1.4 3.2 3 0 0 3 3 3 0 A9 protein conserved region FAD_binding_4 PF01565.23 ETS85960.1 - 3.2e-20 72.3 0.7 1.7e-19 69.9 0.3 2.2 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.12 ETS85960.1 - 0.00011 22.2 0.2 0.00029 20.9 0.2 1.8 1 0 0 1 1 1 1 Berberine and berberine like ketoacyl-synt PF00109.26 ETS85961.1 - 1.1e-70 238.1 0.4 1.9e-70 237.4 0.4 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ETS85961.1 - 2.8e-32 111.2 0.0 6.9e-32 109.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 ETS85961.1 - 2.5e-21 75.8 1.3 1.7e-12 47.5 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Acyl_transf_1 PF00698.21 ETS85961.1 - 9.8e-19 68.0 0.0 1.7e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.12 ETS85961.1 - 2.8e-18 66.5 0.0 8.4e-18 65.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain HTH_51 PF18558.1 ETS85961.1 - 4.5e-16 58.5 0.0 1.3e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain PS-DH PF14765.6 ETS85961.1 - 4.4e-13 49.1 0.0 8e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_25 PF13649.6 ETS85961.1 - 2.5e-12 47.3 0.0 7.2e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS85961.1 - 5.2e-11 43.0 0.0 3.1e-10 40.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS85961.1 - 2.8e-10 40.3 0.0 6.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS85961.1 - 2.4e-08 33.9 0.0 5.9e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ETS85961.1 - 9.5e-08 32.5 0.0 4.4e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Ubie_methyltran PF01209.18 ETS85961.1 - 3.6e-05 23.2 0.0 0.00014 21.3 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 ETS85961.1 - 0.00085 19.1 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Thiolase_N PF00108.23 ETS85961.1 - 0.0052 16.2 0.1 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_33 PF10017.9 ETS85961.1 - 0.051 12.7 0.0 0.2 10.7 0.0 1.9 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent HET PF06985.11 ETS85964.1 - 0.00011 22.6 0.1 0.14 12.5 0.0 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_2 PF07719.17 ETS85965.1 - 3.7e-12 45.4 7.6 0.00041 20.3 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 ETS85965.1 - 6.1e-07 29.0 2.6 0.032 14.1 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ETS85965.1 - 2.6e-06 28.0 2.3 0.00041 20.9 0.5 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS85965.1 - 2.1e-05 24.9 0.6 0.00024 21.5 0.1 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ETS85965.1 - 6.8e-05 23.1 6.4 0.0035 17.6 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 ETS85965.1 - 8.6e-05 23.0 1.9 6.2 7.9 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 ETS85965.1 - 0.0026 18.3 0.3 2.3 9.0 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ETS85965.1 - 0.0061 16.7 2.4 4.1 7.8 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 ETS85965.1 - 0.013 15.2 0.5 0.74 9.5 0.0 3.2 3 0 0 3 3 3 0 TPR repeat TPR_7 PF13176.6 ETS85965.1 - 0.046 13.7 1.1 30 4.9 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 ETS85965.1 - 0.068 13.1 2.6 46 4.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat S6PP_C PF08472.10 ETS85965.1 - 0.1 12.4 0.1 17 5.3 0.1 2.9 2 1 0 3 3 3 0 Sucrose-6-phosphate phosphohydrolase C-terminal TPR_12 PF13424.6 ETS85966.1 - 3.1e-12 46.6 15.7 2.7e-05 24.4 0.3 5.2 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 ETS85966.1 - 0.11 12.4 14.9 9.7 6.2 0.5 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat p450 PF00067.22 ETS85967.1 - 2.4e-50 171.6 0.0 3.2e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Croc_4 PF17691.1 ETS85967.1 - 0.056 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Contingent replication of cDNA 4 LEF-9 PF05094.12 ETS85967.1 - 0.13 10.8 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Late expression factor 9 (LEF-9) MFS_1 PF07690.16 ETS85968.1 - 1e-43 149.7 28.1 1e-43 149.7 28.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS85968.1 - 5.1e-09 35.5 13.4 5.1e-09 35.5 13.4 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 ETS85968.1 - 4.1 5.6 9.9 0.56 8.4 1.5 2.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 ETS85968.1 - 8.6 4.6 16.4 0.33 9.3 5.2 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector PAP2 PF01569.21 ETS85969.1 - 1e-21 77.2 0.3 5.1e-21 74.9 0.3 2.1 1 1 0 1 1 1 1 PAP2 superfamily Sulf_transp PF04143.14 ETS85969.1 - 0.0041 16.7 1.0 0.0066 16.1 1.0 1.5 1 1 0 1 1 1 1 Sulphur transport Fungal_trans PF04082.18 ETS85970.1 - 4.5e-10 39.0 2.3 7.6e-10 38.3 0.3 2.2 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS85970.1 - 0.005 16.9 9.8 0.0098 16.0 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 ETS85971.1 - 1.3e-66 225.2 0.0 1.7e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Flu_NP PF00506.18 ETS85971.1 - 0.24 10.0 0.0 0.34 9.5 0.0 1.1 1 0 0 1 1 1 0 Influenza virus nucleoprotein adh_short_C2 PF13561.6 ETS85972.1 - 5e-52 176.8 0.0 6.2e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS85972.1 - 4.9e-42 143.6 0.1 6.1e-42 143.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS85972.1 - 1.2e-08 35.1 0.1 1.6e-08 34.7 0.1 1.1 1 0 0 1 1 1 1 KR domain DFP PF04127.15 ETS85972.1 - 0.0023 17.8 0.6 0.0035 17.2 0.6 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Pyr_redox_3 PF13738.6 ETS85972.1 - 0.15 11.3 0.2 0.21 10.8 0.2 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Wax2_C PF12076.8 ETS85972.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 WAX2 C-terminal domain Epimerase PF01370.21 ETS85972.1 - 0.19 11.1 0.3 0.39 10.1 0.3 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AXE1 PF05448.12 ETS85972.1 - 0.21 10.2 0.0 0.31 9.7 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) TauD PF02668.16 ETS85973.1 - 8.7e-57 192.9 0.5 1.6e-56 192.1 0.5 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 4HBT_3 PF13622.6 ETS85974.1 - 2e-42 146.2 0.0 2.5e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Metallophos PF00149.28 ETS85975.1 - 2.7e-20 73.7 0.2 4.4e-20 73.1 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 ETS85975.1 - 2.5e-17 63.5 0.5 7.9e-17 61.9 0.5 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 ETS85975.1 - 1.5e-13 51.1 2.2 2.8e-13 50.2 1.1 2.1 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 ETS85975.1 - 0.0034 17.9 0.0 0.0091 16.5 0.0 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain fn3 PF00041.21 ETS85975.1 - 0.11 12.8 1.1 0.32 11.4 1.1 1.7 1 0 0 1 1 1 0 Fibronectin type III domain F-box-like PF12937.7 ETS85976.1 - 0.00069 19.5 2.1 0.0013 18.5 2.1 1.5 1 0 0 1 1 1 1 F-box-like RXT2_N PF08595.11 ETS85976.1 - 0.0074 16.3 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 1 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 ETS85976.1 - 0.0092 16.3 6.3 0.019 15.3 6.3 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain F-box PF00646.33 ETS85976.1 - 0.014 15.3 0.5 0.046 13.6 0.5 1.9 1 0 0 1 1 1 0 F-box domain DNA_pol_phi PF04931.13 ETS85976.1 - 1 7.4 6.7 1.4 7.0 6.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 ETS85976.1 - 1.8 8.2 7.9 2.9 7.6 7.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 ETS85976.1 - 5.3 5.2 4.9 7.4 4.7 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein PepX_C PF08530.10 ETS85977.1 - 2.7e-20 73.3 0.0 4.2e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 ETS85977.1 - 0.011 15.3 0.4 0.2 11.2 0.1 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3426 PF11906.8 ETS85977.1 - 0.15 12.3 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) Peptidase_S15 PF02129.18 ETS85978.1 - 1.6e-23 83.7 0.4 2.5e-23 83.0 0.4 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 ETS85978.1 - 0.02 13.6 0.0 2.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) p450 PF00067.22 ETS85980.1 - 1.9e-43 148.9 0.0 2.3e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS85981.1 - 7.6e-18 64.5 0.0 1.5e-16 60.2 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 DUF2070 PF09843.9 ETS85982.1 - 1.1 7.4 4.6 1.3 7.3 4.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) p450 PF00067.22 ETS85983.1 - 9.4e-31 107.1 0.0 1.7e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 ETS85984.1 - 9.6e-37 126.7 50.0 9.6e-37 126.7 50.0 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS85984.1 - 6.9e-11 41.3 16.5 6.9e-11 41.3 16.5 2.0 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MCU PF04678.13 ETS85984.1 - 0.045 13.9 0.4 0.11 12.5 0.4 1.6 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF3433 PF11915.8 ETS85985.1 - 3.5e-23 81.9 22.6 3.9e-20 72.1 0.9 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) COX2_TM PF02790.15 ETS85985.1 - 0.0006 19.9 0.1 0.65 10.2 0.0 3.1 2 0 0 2 2 2 2 Cytochrome C oxidase subunit II, transmembrane domain HET PF06985.11 ETS85986.1 - 1.4e-23 83.9 0.0 2.6e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cupin_1 PF00190.22 ETS85987.1 - 2.2e-39 134.5 0.0 6.9e-19 67.9 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 ETS85987.1 - 2.4e-23 81.6 1.3 1.2e-11 44.1 0.1 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 ETS85987.1 - 6.6e-08 32.6 0.6 0.0025 17.7 0.1 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 ETS85987.1 - 1.4e-06 27.9 0.1 0.047 13.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.7 ETS85987.1 - 0.0021 17.8 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 2 Cupin SBP56 PF05694.11 ETS85988.1 - 1.3e-07 30.9 0.0 1.2e-06 27.7 0.0 2.0 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 ETS85988.1 - 0.00013 21.3 0.1 0.29 10.4 0.0 2.9 2 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller NHL PF01436.21 ETS85988.1 - 0.042 13.9 0.1 2.4 8.3 0.0 3.3 3 1 1 4 4 4 0 NHL repeat PQQ_3 PF13570.6 ETS85988.1 - 0.39 11.3 2.3 0.53 10.8 0.3 2.3 2 0 0 2 2 2 0 PQQ-like domain An_peroxidase PF03098.15 ETS85989.1 - 6.1e-46 157.1 0.0 4.7e-32 111.3 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 ETS85989.1 - 7.6e-05 21.6 0.0 0.00027 19.8 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 MAPEG PF01124.18 ETS85990.1 - 1.2e-21 77.0 5.7 1.4e-21 76.7 5.7 1.2 1 0 0 1 1 1 1 MAPEG family MetOD2 PF18548.1 ETS85990.1 - 0.2 11.8 0.0 0.43 10.7 0.0 1.5 1 0 0 1 1 1 0 Metanogen output domain 2 adh_short PF00106.25 ETS85991.1 - 2.2e-14 53.4 0.0 3.2e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS85991.1 - 5.3e-11 42.5 0.0 6.9e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ETS85991.1 - 0.035 13.6 0.0 0.37 10.2 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh PF00389.30 ETS85991.1 - 0.057 13.1 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Fungal_trans_2 PF11951.8 ETS85992.1 - 2.1e-25 89.3 0.0 2.5e-24 85.8 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS85992.1 - 1.7e-06 28.1 12.4 4.1e-06 26.8 12.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu_amine_oxid PF01179.20 ETS85993.1 - 1.5e-149 498.4 0.0 1.8e-149 498.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 ETS85993.1 - 1.2e-19 70.6 0.0 5.4e-19 68.5 0.0 2.1 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 ETS85993.1 - 4.5e-09 36.4 0.0 9.7e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain AA_permease_2 PF13520.6 ETS85994.1 - 5.5e-55 186.9 42.6 6.8e-55 186.6 42.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS85994.1 - 1.5e-21 76.6 35.5 2.1e-21 76.1 35.5 1.1 1 0 0 1 1 1 1 Amino acid permease Aldedh PF00171.22 ETS85995.1 - 5.9e-183 608.6 0.1 6.7e-183 608.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ETS85995.1 - 0.16 11.4 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) RPAP1_N PF08621.10 ETS85997.1 - 6.2 6.7 5.6 0.95 9.3 0.1 2.4 3 0 0 3 3 3 0 RPAP1-like, N-terminal FUSC PF04632.12 ETS85998.1 - 0.083 11.4 0.0 0.088 11.3 0.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ank_2 PF12796.7 ETS85999.1 - 9.8e-39 131.8 1.6 2.1e-13 50.7 0.0 5.7 3 1 3 6 6 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 ETS85999.1 - 6.4e-34 114.9 2.4 3.9e-05 23.9 0.0 9.3 6 2 3 9 9 9 6 Ankyrin repeat Ank_3 PF13606.6 ETS85999.1 - 6.1e-25 84.6 0.2 0.016 15.7 0.0 8.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 ETS85999.1 - 2e-19 69.7 0.1 0.00099 19.6 0.0 5.7 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS85999.1 - 9e-16 57.7 5.8 0.0039 17.5 0.2 6.5 2 1 3 6 6 6 4 Ankyrin repeats (many copies) NACHT PF05729.12 ETS85999.1 - 8.5e-12 45.3 0.2 4.2e-11 43.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Helo_like_N PF17111.5 ETS85999.1 - 0.00024 20.6 0.0 0.00053 19.4 0.0 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 ETS85999.1 - 0.0016 18.7 0.0 0.0068 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS85999.1 - 0.0018 18.7 0.0 0.0063 16.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain SesA PF17107.5 ETS85999.1 - 0.02 15.1 0.2 0.39 10.9 0.0 2.9 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases NB-ARC PF00931.22 ETS85999.1 - 0.061 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Nuc_rec_co-act PF08815.10 ETS85999.1 - 0.065 13.1 0.0 3.9 7.4 0.2 2.8 2 0 0 2 2 2 0 Nuclear receptor coactivator Glyco_hydro_61 PF03443.14 ETS86000.1 - 8.4e-68 228.3 0.1 8.4e-68 228.3 0.1 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Med3 PF11593.8 ETS86000.1 - 0.22 10.7 14.0 0.31 10.2 14.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NICE-3 PF07406.11 ETS86001.1 - 2.2e-08 34.3 0.3 0.0028 17.7 0.0 2.9 3 0 0 3 3 3 2 NICE-3 protein DUF4129 PF13559.6 ETS86001.1 - 0.00055 20.1 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) PAP2_3 PF14378.6 ETS86001.1 - 0.068 12.9 3.2 0.11 12.2 3.2 1.3 1 0 0 1 1 1 0 PAP2 superfamily DUF4231 PF14015.6 ETS86001.1 - 0.82 10.2 3.2 1.7 9.2 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Ndc1_Nup PF09531.10 ETS86002.1 - 2.2e-176 588.2 0.8 2.6e-176 588.0 0.8 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.6 ETS86003.1 - 2.4e-21 76.0 2.0 2.4e-21 76.0 2.0 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 ETS86003.1 - 1.7e-13 50.3 0.3 4.6e-13 49.0 0.3 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 ETS86003.1 - 0.0011 18.7 10.2 0.0029 17.3 10.2 1.7 1 1 0 1 1 1 1 Syntaxin Nucleolin_bd PF16725.5 ETS86003.1 - 0.004 16.8 0.0 0.0098 15.5 0.0 1.6 1 0 0 1 1 1 1 Nucleolin binding domain DUF1664 PF07889.12 ETS86003.1 - 0.008 16.2 7.8 2.4 8.2 0.0 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) EF-hand_14 PF17959.1 ETS86003.1 - 0.035 14.5 0.4 0.099 13.0 0.4 1.9 1 1 0 1 1 1 0 EF-hand domain Sec34 PF04136.15 ETS86003.1 - 0.05 13.5 0.2 0.05 13.5 0.2 2.4 2 1 1 3 3 3 0 Sec34-like family Synaptobrevin PF00957.21 ETS86003.1 - 0.19 11.5 4.0 0.084 12.7 0.5 2.3 2 1 1 3 3 3 0 Synaptobrevin Spectrin PF00435.21 ETS86003.1 - 0.33 11.4 13.7 17 5.9 11.1 3.0 1 1 2 3 3 3 0 Spectrin repeat Prominin PF05478.11 ETS86003.1 - 0.62 7.9 7.2 2.8 5.8 0.3 2.0 1 1 1 2 2 2 0 Prominin TMPIT PF07851.13 ETS86003.1 - 2.1 7.5 5.7 7 5.8 2.4 2.1 1 1 2 3 3 3 0 TMPIT-like protein YabA PF06156.13 ETS86003.1 - 3 8.6 6.7 2 9.1 0.1 2.9 2 1 1 3 3 3 0 Initiation control protein YabA T2SSF PF00482.23 ETS86003.1 - 5.2 7.0 7.8 23 4.9 5.0 3.0 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F BLM10_N PF16547.5 ETS86004.1 - 0.018 15.3 0.0 0.049 13.9 0.0 1.7 2 0 0 2 2 2 0 Proteasome-substrate-size regulator, N-terminal ALG11_N PF15924.5 ETS86005.1 - 2.6e-82 275.9 0.0 3.5e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 ETS86005.1 - 4.4e-20 71.9 0.0 7.2e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ETS86005.1 - 6.2e-10 39.6 0.0 1.8e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ETS86005.1 - 0.077 13.0 0.0 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase Family 4 MFS_1 PF07690.16 ETS86006.1 - 1.1e-13 50.8 30.2 1.1e-13 50.8 30.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ETS86006.1 - 2.2e-08 34.0 8.5 2.2e-08 34.0 8.5 2.9 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 ETS86006.1 - 1.6e-05 24.0 9.6 1.6e-05 24.0 9.6 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3169 PF11368.8 ETS86006.1 - 0.039 13.5 0.0 0.58 9.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) TauD PF02668.16 ETS86007.1 - 6.2e-29 101.6 0.0 1e-28 100.9 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family F-box PF00646.33 ETS86008.1 - 7.9e-05 22.4 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ETS86008.1 - 0.00039 20.3 0.1 0.00086 19.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like HTH_32 PF13565.6 ETS86008.1 - 0.014 16.0 0.3 0.046 14.3 0.3 1.9 1 0 0 1 1 1 0 Homeodomain-like domain EthD PF07110.11 ETS86009.1 - 2.3e-09 38.3 0.0 3e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 ETS86009.1 - 0.11 13.0 0.0 0.23 11.9 0.0 1.6 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase Ank_4 PF13637.6 ETS86010.1 - 9e-07 29.3 0.0 0.0015 19.0 0.0 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS86010.1 - 0.00017 21.7 0.2 1.4 9.7 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 ETS86010.1 - 0.0002 21.9 0.0 0.00079 20.0 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS86010.1 - 0.00048 20.4 0.1 0.026 14.8 0.0 3.1 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Tyrosinase PF00264.20 ETS86011.1 - 4e-38 131.9 9.0 6.2e-38 131.3 9.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Kelch_1 PF01344.25 ETS86012.1 - 0.0012 18.3 0.2 0.87 9.2 0.0 3.1 3 0 0 3 3 3 2 Kelch motif ASTN_2_hairpin PF18577.1 ETS86012.1 - 0.036 14.2 0.0 2 8.6 0.0 2.3 2 0 0 2 2 2 0 Astrotactin-2 C-terminal beta-hairpin domain SoxD PF04267.12 ETS86012.1 - 0.076 13.1 0.6 0.65 10.1 0.1 2.0 1 1 1 2 2 2 0 Sarcosine oxidase, delta subunit family Glyco_transf_9 PF01075.17 ETS86013.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) adh_short PF00106.25 ETS86014.1 - 2.3e-25 89.2 0.1 3e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS86014.1 - 1.6e-16 60.6 0.1 2.2e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ETS86014.1 - 5.4e-05 22.8 0.1 0.25 10.8 0.1 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 ETS86014.1 - 0.00011 22.2 0.1 0.00019 21.4 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ETS86014.1 - 0.012 15.5 0.5 0.031 14.2 0.5 1.7 1 1 0 1 1 1 0 NAD(P)H-binding TadZ_N PF16968.5 ETS86014.1 - 0.045 13.5 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Pilus assembly protein TadZ N-terminal TrkA_N PF02254.18 ETS86014.1 - 0.078 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain EthD PF07110.11 ETS86015.1 - 7.6e-09 36.6 0.0 9.7e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 EthD domain DUF4286 PF14114.6 ETS86015.1 - 0.037 14.5 0.2 0.063 13.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Trp_DMAT PF11991.8 ETS86017.1 - 1.1e-86 291.5 0.0 1.3e-86 291.3 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Cupin_2 PF07883.11 ETS86018.1 - 3.8e-05 23.3 0.1 5.9e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Cupin domain adh_short PF00106.25 ETS86019.1 - 3e-10 39.9 0.3 7.8e-10 38.5 0.3 1.7 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS86019.1 - 6.7e-06 25.8 0.1 8.7e-06 25.5 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS86019.1 - 1.6e-05 24.9 1.4 2.1e-05 24.5 0.2 1.7 2 0 0 2 2 2 1 KR domain NmrA PF05368.13 ETS86019.1 - 7.4e-05 22.4 2.4 0.00013 21.6 2.4 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ETS86019.1 - 0.13 11.8 0.3 0.17 11.3 0.3 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.23 ETS86020.1 - 1e-21 77.1 1.1 2.3e-21 76.0 1.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS86020.1 - 0.00034 20.6 0.2 0.001 19.1 0.2 1.8 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans_2 PF11951.8 ETS86021.1 - 2.8e-33 115.3 0.9 3.7e-33 114.9 0.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 ETS86022.1 - 4.3e-18 65.5 0.0 1.2e-15 57.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS86022.1 - 4.3e-11 42.8 0.0 1.8e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS86022.1 - 0.0028 17.6 0.0 0.0043 17.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS86022.1 - 0.036 13.5 0.0 0.094 12.2 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ETS86022.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Zn_clus PF00172.18 ETS86023.1 - 6.6e-09 35.8 6.4 1.7e-08 34.5 6.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS86023.1 - 5e-05 22.5 0.0 0.00017 20.7 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain CAP_N PF01213.19 ETS86023.1 - 3.3 7.1 7.0 5.6 6.4 7.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Helo_like_N PF17111.5 ETS86024.1 - 2.2e-12 46.8 0.9 4.5e-12 45.8 0.2 1.9 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Ank_4 PF13637.6 ETS86024.1 - 2.4e-07 31.2 0.3 0.067 13.8 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) NACHT PF05729.12 ETS86024.1 - 3.8e-07 30.2 0.0 1.4e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 NACHT domain Ank_2 PF12796.7 ETS86024.1 - 1.4e-06 28.8 0.2 0.00014 22.4 0.1 3.8 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) AAA_16 PF13191.6 ETS86024.1 - 0.00091 19.6 0.0 0.0037 17.7 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS86024.1 - 0.0039 17.4 0.1 0.061 13.6 0.0 2.9 2 1 1 3 3 3 1 AAA domain Ank_5 PF13857.6 ETS86024.1 - 0.018 15.4 0.3 54 4.3 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS86024.1 - 0.067 13.8 0.3 1.1e+02 3.9 0.0 5.2 5 0 0 5 5 5 0 Ankyrin repeat AAA PF00004.29 ETS86024.1 - 0.08 13.4 0.0 0.56 10.6 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ank_2 PF12796.7 ETS86025.1 - 4.6e-23 81.6 0.3 5e-12 46.2 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS86025.1 - 8.1e-21 74.1 7.2 1.5e-08 35.0 0.1 5.8 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS86025.1 - 1.3e-15 57.2 3.0 7.4e-05 22.9 0.0 5.9 3 2 4 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 ETS86025.1 - 1.5e-14 53.6 1.8 0.00074 19.9 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 ETS86025.1 - 1.7e-11 43.3 7.9 0.025 15.1 0.0 7.8 8 1 1 9 9 9 2 Ankyrin repeat Ank_2 PF12796.7 ETS86026.1 - 2.5e-05 24.8 0.0 0.00032 21.2 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS86026.1 - 0.0012 19.2 0.1 0.55 11.0 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 ETS86026.1 - 0.0067 17.0 0.0 0.55 10.9 0.0 3.6 4 2 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 ETS86026.1 - 0.034 14.6 0.1 1 9.9 0.0 3.2 4 0 0 4 4 4 0 Ankyrin repeat DNA_pol_A_exo1 PF01612.20 ETS86027.1 - 1.5e-11 44.4 0.0 2.6e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease DNA_pol_B_2 PF03175.13 ETS86027.1 - 0.029 13.2 0.0 0.042 12.7 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral FAR1 PF03101.15 ETS86028.1 - 5.1e-06 27.1 0.4 8.8e-06 26.3 0.4 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain Hemagglutinin PF00509.18 ETS86028.1 - 0.0037 15.7 0.0 0.0045 15.5 0.0 1.1 1 0 0 1 1 1 1 Haemagglutinin Snapin_Pallidin PF14712.6 ETS86028.1 - 0.0078 16.6 0.4 0.015 15.7 0.4 1.4 1 0 0 1 1 1 1 Snapin/Pallidin DUF1664 PF07889.12 ETS86028.1 - 0.014 15.4 0.8 0.029 14.4 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) AFT PF08731.11 ETS86028.1 - 0.016 15.6 0.1 0.03 14.7 0.1 1.5 1 0 0 1 1 1 0 Transcription factor AFT CCDC53 PF10152.9 ETS86028.1 - 0.025 15.0 0.3 0.043 14.2 0.1 1.5 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex XhlA PF10779.9 ETS86028.1 - 0.05 13.8 0.2 0.26 11.5 0.1 2.0 1 1 1 2 2 2 0 Haemolysin XhlA Baculo_PEP_C PF04513.12 ETS86028.1 - 0.078 13.0 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pannexin_like PF12534.8 ETS86028.1 - 0.12 11.5 0.1 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 CdvA PF18822.1 ETS86028.1 - 0.14 12.0 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 CdvA-like coiled-coil domain eIF-3c_N PF05470.12 ETS86030.1 - 2e-177 591.1 22.0 2e-177 591.1 22.0 3.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 ETS86030.1 - 2e-13 50.8 0.0 1.3e-12 48.1 0.0 2.5 2 1 1 3 3 3 1 PCI domain CDC45 PF02724.14 ETS86030.1 - 0.077 11.3 18.2 0.12 10.6 18.2 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 ETS86030.1 - 2.2 7.3 30.2 4.6 6.3 30.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GRP PF07172.11 ETS86030.1 - 9.3 7.0 19.6 0.079 13.7 10.1 2.3 2 0 0 2 2 2 0 Glycine rich protein family Hemerythrin PF01814.23 ETS86031.1 - 1.6e-13 51.4 4.0 2.2e-13 50.9 4.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain NACHT PF05729.12 ETS86033.1 - 1.9e-11 44.2 0.0 5.1e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain HET PF06985.11 ETS86033.1 - 5.4e-11 43.0 9.5 5.7e-07 30.0 9.5 3.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 ETS86033.1 - 2.1e-10 41.0 2.3 0.0019 19.0 0.1 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat AAA_16 PF13191.6 ETS86033.1 - 6e-06 26.7 0.5 2.4e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ANAPC4_WD40 PF12894.7 ETS86033.1 - 0.00031 21.0 0.0 1.9 8.8 0.0 3.3 1 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_22 PF13401.6 ETS86033.1 - 0.0013 19.0 0.0 0.0034 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain PD40 PF07676.12 ETS86033.1 - 0.0028 17.6 0.2 8.5 6.4 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat VID27 PF08553.10 ETS86033.1 - 0.0053 15.9 0.0 0.0081 15.3 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain AAA_30 PF13604.6 ETS86033.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ETS86033.1 - 0.035 14.6 0.0 0.12 12.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ETS86033.1 - 0.045 13.7 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MFS_1 PF07690.16 ETS86034.1 - 5.7e-27 94.6 22.7 5.7e-27 94.6 22.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Aldo_ket_red PF00248.21 ETS86035.1 - 4.8e-23 81.8 0.0 5.3e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PAN_4 PF14295.6 ETS86036.1 - 0.00059 19.7 0.5 0.0016 18.3 0.5 1.8 1 1 0 1 1 1 1 PAN domain PAN_1 PF00024.26 ETS86036.1 - 0.0036 17.2 0.4 0.0067 16.4 0.4 1.4 1 0 0 1 1 1 1 PAN domain ApoL PF05461.11 ETS86037.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein L CFEM PF05730.11 ETS86038.1 - 9.4e-11 41.7 6.0 1.7e-10 40.8 6.0 1.4 1 0 0 1 1 1 1 CFEM domain DUF639 PF04842.12 ETS86038.1 - 2.8 7.3 7.6 3.6 6.9 0.5 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) DUF3474 PF11960.8 ETS86039.1 - 0.008 16.4 3.6 0.022 15.0 0.4 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3474) EHN PF06441.12 ETS86040.1 - 5.8e-38 129.6 0.4 1.1e-36 125.5 0.0 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ETS86040.1 - 1.1e-11 44.9 0.0 2e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS86040.1 - 0.0056 17.3 0.1 0.23 12.0 0.1 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family MatE PF01554.18 ETS86041.1 - 3.9e-53 179.4 24.9 1.7e-35 122.0 9.3 2.3 2 0 0 2 2 2 2 MatE DUF1440 PF07274.12 ETS86041.1 - 0.063 13.6 0.9 3 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) AA_permease PF00324.21 ETS86043.1 - 3.4e-114 382.1 47.3 4.2e-114 381.8 47.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS86043.1 - 1.4e-33 116.3 46.8 1.8e-33 116.1 46.8 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 ETS86044.1 - 4.9e-39 134.3 70.1 3.2e-34 118.4 41.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS86044.1 - 1.9e-11 43.5 28.7 5e-06 25.7 9.1 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 ETS86044.1 - 2.8e-05 22.9 10.7 2.8e-05 22.9 10.7 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein Abhydrolase_1 PF00561.20 ETS86045.1 - 1.2e-08 35.0 0.0 3.1e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS86045.1 - 0.0047 17.5 0.1 0.0067 17.1 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ETS86045.1 - 0.033 13.7 0.0 0.48 9.8 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ETS86045.1 - 0.1 11.8 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 TPR_2 PF07719.17 ETS86046.1 - 0.044 13.9 1.1 0.1 12.8 0.4 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat LCCL PF03815.19 ETS86047.1 - 3.1e-19 68.9 1.3 5.3e-19 68.1 1.3 1.3 1 0 0 1 1 1 1 LCCL domain DUF212 PF02681.14 ETS86047.1 - 0.062 13.4 0.0 0.2 11.8 0.0 1.7 1 1 0 1 1 1 0 Divergent PAP2 family TGT PF01702.18 ETS86048.1 - 3.1e-68 230.5 0.0 3.7e-68 230.2 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Alk_phosphatase PF00245.20 ETS86049.1 - 1.5e-68 231.7 0.1 6e-68 229.7 0.1 1.8 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.22 ETS86049.1 - 1.5e-05 24.8 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ETS86049.1 - 4.5e-05 23.0 0.0 0.0001 21.8 0.0 1.7 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 ETS86049.1 - 0.028 13.1 0.2 0.049 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 ETS86049.1 - 0.03 13.7 0.6 0.092 12.1 0.2 1.8 2 0 0 2 2 2 0 Metalloenzyme superfamily AA_permease_2 PF13520.6 ETS86050.1 - 1.2e-52 179.2 56.5 1.5e-52 178.9 56.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS86050.1 - 8.4e-23 80.7 47.9 1.1e-22 80.3 47.9 1.1 1 0 0 1 1 1 1 Amino acid permease Cu_amine_oxid PF01179.20 ETS86051.1 - 1.5e-166 554.4 0.0 1.9e-166 554.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 ETS86051.1 - 1.9e-06 28.0 0.0 4.5e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 ETS86051.1 - 0.0043 17.4 0.0 0.0097 16.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Fungal_trans PF04082.18 ETS86052.1 - 3.6e-11 42.6 0.2 7.7e-11 41.5 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain SSFA2_C PF14723.6 ETS86052.1 - 0.024 14.6 0.1 0.08 12.8 0.1 2.0 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus YscO PF07321.12 ETS86052.1 - 0.21 11.6 1.5 0.24 11.3 0.1 1.7 2 0 0 2 2 2 0 Type III secretion protein YscO ADH_N PF08240.12 ETS86053.1 - 2e-30 104.8 0.9 3.5e-30 104.1 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS86053.1 - 2.3e-13 50.3 0.0 3.3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ETS86053.1 - 1.6e-07 31.0 0.2 1.3e-06 28.0 0.2 2.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Prot_ATP_ID_OB PF16450.5 ETS86053.1 - 0.062 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Transketolase_N PF00456.21 ETS86054.1 - 2.3e-123 411.4 0.0 3e-123 411.1 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ETS86054.1 - 2e-37 128.6 0.0 3.4e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.6 ETS86054.1 - 1.8e-09 37.2 0.0 6.4e-08 32.1 0.0 2.4 2 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.20 ETS86054.1 - 3.8e-07 30.0 0.0 1.5e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 ETS86054.1 - 0.0003 20.6 1.2 0.0023 17.7 0.8 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 ETS86054.1 - 0.014 14.4 0.1 0.025 13.6 0.1 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component HAD_SAK_2 PF18143.1 ETS86054.1 - 0.13 12.6 0.0 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins Fungal_trans_2 PF11951.8 ETS86055.1 - 1.4e-13 50.5 1.8 9.1e-13 47.8 1.8 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 ETS86055.1 - 0.0059 15.7 0.0 0.0095 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2TM PF13239.6 ETS86056.1 - 0.0018 18.6 1.7 0.0037 17.5 1.7 1.5 1 0 0 1 1 1 1 2TM domain zf-C2H2_4 PF13894.6 ETS86056.1 - 0.066 14.1 2.5 8.3 7.6 0.8 3.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ETS86056.1 - 0.13 12.5 0.4 0.3 11.4 0.4 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ETS86056.1 - 0.25 11.2 4.3 2.5 7.9 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 ETS86056.1 - 0.27 11.8 10.4 1.3 9.7 1.6 3.0 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_12 PF18658.1 ETS86056.1 - 0.35 10.5 3.0 15 5.3 0.8 2.4 1 1 1 2 2 2 0 Zinc-finger C2H2-type zf_Hakai PF18408.1 ETS86056.1 - 1.1 9.0 6.3 1.4 8.7 2.0 2.6 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zf-H2C2_2 PF13465.6 ETS86056.1 - 3.6 8.2 6.6 6.4 7.4 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger double domain End_beta_barrel PF12195.8 ETS86057.1 - 0.16 11.9 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase Internalin_N PF12354.8 ETS86058.1 - 0.048 13.7 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal GMC_oxred_C PF05199.13 ETS86059.1 - 3.5e-26 92.4 0.0 6.7e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 ETS86059.1 - 5.7e-24 85.0 0.0 1e-21 77.6 0.0 3.0 2 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 ETS86059.1 - 0.00027 20.3 0.1 0.00085 18.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS86059.1 - 0.012 15.9 0.3 0.036 14.3 0.3 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS86059.1 - 0.039 13.1 1.1 0.082 12.0 0.7 1.7 2 0 0 2 2 2 0 FAD binding domain Kelch_1 PF01344.25 ETS86059.1 - 0.083 12.5 0.2 11 5.7 0.1 2.4 2 0 0 2 2 2 0 Kelch motif Pyr_redox_3 PF13738.6 ETS86059.1 - 0.11 11.8 0.0 8.9 5.5 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS86059.1 - 0.14 11.4 0.5 0.3 10.3 0.5 1.4 1 0 0 1 1 1 0 FAD binding domain CFEM PF05730.11 ETS86060.1 - 9.5e-11 41.6 9.0 1.9e-10 40.7 9.0 1.5 1 0 0 1 1 1 1 CFEM domain Fungal_trans_2 PF11951.8 ETS86061.1 - 7.1e-07 28.4 0.1 4.1e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain DIOX_N PF14226.6 ETS86062.1 - 2.6e-26 92.7 0.0 3.9e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS86062.1 - 2.9e-19 69.4 0.0 5.4e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.15 ETS86063.1 - 3.8e-92 309.4 38.7 4.8e-92 309.0 38.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Nairovirus_M PF07948.11 ETS86063.1 - 0.069 11.4 0.1 0.1 10.8 0.1 1.1 1 0 0 1 1 1 0 Nairovirus M polyprotein-like zf-LITAF-like PF10601.9 ETS86064.1 - 0.013 15.7 0.2 0.029 14.6 0.0 1.6 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Aldo_ket_red PF00248.21 ETS86065.1 - 1.4e-68 231.2 0.0 1.6e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_tail_X PF05489.12 ETS86065.1 - 0.0044 16.7 0.1 0.022 14.4 0.0 2.0 2 0 0 2 2 2 1 Phage Tail Protein X Sulphotransf PF09037.10 ETS86065.1 - 0.005 16.4 0.1 0.015 14.8 0.0 1.8 2 0 0 2 2 2 1 Stf0 sulphotransferase DHC_N2 PF08393.13 ETS86066.1 - 0.11 11.5 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 HeLo PF14479.6 ETS86067.1 - 0.038 13.8 0.3 0.067 13.0 0.3 1.5 1 0 0 1 1 1 0 Prion-inhibition and propagation Alginate_lyase PF05426.12 ETS86071.1 - 3.7e-08 33.2 5.1 9e-08 32.0 5.1 1.5 1 1 0 1 1 1 1 Alginate lyase Fasciclin PF02469.22 ETS86072.1 - 2e-19 70.1 0.0 2.7e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain DUF4993 PF16384.5 ETS86072.1 - 0.036 13.1 0.3 0.052 12.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF1931 PF09123.11 ETS86072.1 - 0.15 12.2 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Melibiase_2 PF16499.5 ETS86073.1 - 1.1e-53 182.3 5.0 1.2e-52 178.9 5.0 2.0 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 ETS86073.1 - 1.7e-11 44.0 0.1 3.3e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 ETS86073.1 - 2.2e-06 26.9 0.0 3.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Melibiase Glyco_hydro_97 PF10566.9 ETS86073.1 - 0.0067 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 97 Raffinose_syn PF05691.12 ETS86073.1 - 0.011 13.6 0.0 0.014 13.3 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 DUF4431 PF14485.6 ETS86073.1 - 0.057 13.2 0.2 0.29 11.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) DUF3489 PF11994.8 ETS86074.1 - 0.00019 21.4 0.2 0.00019 21.4 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3489) Qn_am_d_aII PF14930.6 ETS86074.1 - 0.00068 19.9 0.9 0.001 19.3 0.9 1.3 1 0 0 1 1 1 1 Quinohemoprotein amine dehydrogenase, alpha subunit domain II Sigma70_r4 PF04545.16 ETS86074.1 - 0.0041 16.6 1.4 0.0058 16.1 0.2 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Dppa2_A PF14049.6 ETS86074.1 - 0.033 14.3 0.2 0.052 13.7 0.2 1.3 1 0 0 1 1 1 0 Dppa2/4 conserved region in higher vertebrates Peptidase_M3_N PF08439.10 ETS86074.1 - 0.034 14.4 0.2 0.05 13.9 0.2 1.3 1 0 0 1 1 1 0 Oligopeptidase F Cytochrom_C PF00034.21 ETS86074.1 - 0.071 14.3 0.1 0.096 13.8 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c Glyco_hydro_88 PF07470.13 ETS86075.1 - 1.4e-17 63.8 0.8 2e-17 63.3 0.8 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Fungal_trans PF04082.18 ETS86076.1 - 1e-18 67.3 0.0 2.4e-18 66.1 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 ETS86077.1 - 1.9e-33 115.9 25.6 1.2e-32 113.2 26.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS86077.1 - 2.3e-09 37.1 3.3 2.3e-09 37.1 3.3 2.3 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB 2TM PF13239.6 ETS86077.1 - 2 8.8 0.0 2 8.8 0.0 5.0 3 2 0 3 3 3 0 2TM domain CrgA PF06781.12 ETS86077.1 - 2.9 8.0 6.7 90 3.2 5.5 3.1 2 0 0 2 2 2 0 Cell division protein CrgA HET PF06985.11 ETS86078.1 - 5.3e-23 82.0 0.0 9.9e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 ETS86078.1 - 2.7e-15 56.7 0.2 3e-06 27.7 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS86078.1 - 7.5e-14 51.9 0.3 4.9e-08 33.4 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS86078.1 - 1.9e-11 43.1 0.0 0.0014 19.0 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 ETS86078.1 - 1.4e-10 41.2 0.2 1.1e-07 31.9 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS86078.1 - 1.6e-09 37.7 0.1 0.00058 20.2 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat p450 PF00067.22 ETS86079.1 - 5.5e-70 236.4 0.0 7.2e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M26_C PF07580.14 ETS86079.1 - 0.017 13.7 0.0 0.023 13.2 0.0 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region Methyltransf_11 PF08241.12 ETS86080.1 - 2.1e-24 86.0 0.0 3.4e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS86080.1 - 8.2e-23 80.9 0.0 1.5e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS86080.1 - 6e-21 74.8 0.0 8.1e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS86080.1 - 7.1e-18 65.0 0.0 1.1e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS86080.1 - 7.1e-17 61.5 0.0 2.6e-16 59.7 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ETS86080.1 - 1.7e-15 57.5 0.0 3.3e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ETS86080.1 - 1.3e-09 38.1 0.1 2.7e-09 37.1 0.1 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 ETS86080.1 - 2.5e-08 33.7 0.0 4.1e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 ETS86080.1 - 7.2e-08 32.2 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 ETS86080.1 - 3.8e-07 29.7 0.0 4.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Fibrillarin PF01269.17 ETS86080.1 - 0.00013 21.1 0.0 0.00026 20.2 0.0 1.4 1 0 0 1 1 1 1 Fibrillarin Methyltransf_29 PF03141.16 ETS86080.1 - 0.00034 19.3 0.0 0.00049 18.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.6 ETS86080.1 - 0.00037 21.5 0.0 0.00068 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 ETS86080.1 - 0.00044 19.9 0.0 0.00093 18.9 0.0 1.5 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F PrmA PF06325.13 ETS86080.1 - 0.00051 19.5 0.0 0.00088 18.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) ADH_zinc_N PF00107.26 ETS86080.1 - 0.00069 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_9 PF08003.11 ETS86080.1 - 0.0082 15.1 0.0 0.016 14.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 ETS86080.1 - 0.03 13.8 0.0 0.38 10.2 0.0 2.1 1 1 0 1 1 1 0 Putative methyltransferase GCD14 PF08704.10 ETS86080.1 - 0.035 13.8 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit NodS PF05401.11 ETS86080.1 - 0.044 13.4 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 ETS86080.1 - 0.046 13.7 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_7 PF03492.15 ETS86080.1 - 0.055 12.7 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase DREV PF05219.12 ETS86080.1 - 0.06 12.4 0.0 0.4 9.7 0.0 2.0 2 0 0 2 2 2 0 DREV methyltransferase CheR PF01739.18 ETS86080.1 - 0.089 12.3 0.0 0.62 9.5 0.0 2.0 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_3 PF01596.17 ETS86080.1 - 0.09 11.9 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase RrnaAD PF00398.20 ETS86080.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 ETS86080.1 - 0.16 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF3419 PF11899.8 ETS86080.1 - 0.19 10.9 0.0 1.4 8.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3419) DOT1 PF08123.13 ETS86080.1 - 0.19 11.2 0.0 0.93 9.0 0.0 1.9 1 1 1 2 2 2 0 Histone methylation protein DOT1 MFS_1 PF07690.16 ETS86082.1 - 1.3e-48 165.7 38.9 1.3e-48 165.7 38.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS86082.1 - 1.2e-15 57.4 16.2 1.2e-15 57.4 16.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 ETS86082.1 - 7.1e-08 31.3 3.8 1.2e-07 30.6 3.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 ETS86082.1 - 0.0016 16.9 7.5 0.0038 15.6 7.5 1.6 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Sigma_reg_N PF13800.6 ETS86082.1 - 1.3 9.3 0.0 1.3 9.3 0.0 3.2 3 0 0 3 3 3 0 Sigma factor regulator N-terminal TRIQK PF15168.6 ETS86082.1 - 4.4 7.3 6.0 34 4.4 6.0 2.5 1 1 0 1 1 1 0 Triple QxxK/R motif-containing protein family Octopine_DH PF02317.17 ETS86083.1 - 9.5e-40 136.1 0.0 1.4e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.23 ETS86083.1 - 3.3e-07 30.4 0.0 7.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 ETS86083.1 - 4e-05 24.1 0.0 0.0001 22.8 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.6 ETS86083.1 - 5.7e-05 23.3 0.1 0.00013 22.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS86083.1 - 6.7e-05 22.3 0.0 8.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ETS86083.1 - 9.1e-05 22.1 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 ETS86083.1 - 0.00069 19.0 0.0 0.00098 18.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ETS86083.1 - 0.0052 15.5 0.0 0.011 14.5 0.0 1.5 1 1 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 ETS86083.1 - 0.017 14.2 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 ETS86083.1 - 0.022 13.8 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 ETS86083.1 - 0.023 13.9 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 ETS86083.1 - 0.039 14.1 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.22 ETS86083.1 - 0.046 12.8 0.1 0.068 12.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Rossmann-like PF10727.9 ETS86083.1 - 0.15 12.0 0.1 2.4 8.1 0.1 2.3 1 1 0 1 1 1 0 Rossmann-like domain Pec_lyase_C PF00544.19 ETS86084.1 - 1.1e-10 41.5 12.2 2.7e-09 36.9 12.1 2.1 1 1 0 1 1 1 1 Pectate lyase Glyco_hydro_43 PF04616.14 ETS86085.1 - 2.1e-37 129.0 0.2 3.3e-37 128.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ETS86085.1 - 1.2e-09 38.3 0.0 2.3e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Sugar_tr PF00083.24 ETS86086.1 - 2.3e-89 300.3 20.4 1.1e-88 298.1 20.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS86086.1 - 6.9e-23 81.1 11.5 6.9e-23 81.1 11.5 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily HET PF06985.11 ETS86087.1 - 5.4e-29 101.4 0.1 8e-29 100.9 0.1 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ETS86089.1 - 6.5e-32 110.9 0.0 1.3e-31 110.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GP41 PF00517.17 ETS86090.1 - 0.013 15.4 1.3 0.019 14.9 0.2 1.7 2 0 0 2 2 2 0 Retroviral envelope protein O-antigen_lig PF13425.6 ETS86090.1 - 0.11 11.2 0.2 0.14 10.9 0.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein MRPL52 PF18699.1 ETS86090.1 - 0.19 11.9 5.0 0.39 10.9 3.0 2.3 2 0 0 2 2 2 0 Mitoribosomal protein mL52 Csm1_N PF18504.1 ETS86090.1 - 1 9.8 8.6 17 5.8 6.2 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain zinc-ribbons_6 PF07191.12 ETS86090.1 - 1.3 9.1 3.6 14 5.7 3.7 2.2 1 1 0 1 1 1 0 zinc-ribbons DivIC PF04977.15 ETS86090.1 - 1.6 8.5 10.4 0.73 9.6 6.1 2.6 3 0 0 3 3 3 0 Septum formation initiator CorA PF01544.18 ETS86091.1 - 1e-11 44.7 2.1 3.2e-11 43.1 2.1 1.9 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Hydrolase_4 PF12146.8 ETS86091.1 - 0.00011 21.5 0.4 0.00046 19.5 0.0 2.1 3 0 0 3 3 3 1 Serine aminopeptidase, S33 DUF676 PF05057.14 ETS86091.1 - 0.00013 21.5 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 ETS86091.1 - 0.01 16.4 0.6 0.055 14.1 0.0 2.5 3 0 0 3 3 3 0 Alpha/beta hydrolase family Thioesterase PF00975.20 ETS86091.1 - 0.29 11.2 2.9 6.4 6.8 0.0 2.6 2 0 0 2 2 2 0 Thioesterase domain V_ATPase_I PF01496.19 ETS86091.1 - 1.2 7.0 7.3 2 6.3 7.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 ETS86091.1 - 2.8 6.4 10.4 5.9 5.3 10.4 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2434 PF10361.9 ETS86092.1 - 0.96 8.4 6.1 0.17 10.8 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2434) GFA PF04828.14 ETS86093.1 - 3.7e-20 72.0 0.4 6.4e-20 71.3 0.4 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.12 ETS86093.1 - 0.16 12.2 0.0 0.16 12.2 0.0 2.0 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NOB1_Zn_bind PF08772.11 ETS86093.1 - 0.39 10.9 3.6 3.1 8.0 0.1 2.6 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Ribosomal_L27 PF01016.19 ETS86094.1 - 7.8e-29 99.5 0.1 1.9e-28 98.3 0.1 1.7 1 0 0 1 1 1 1 Ribosomal L27 protein DUF2076 PF09849.9 ETS86095.1 - 0.052 13.6 1.0 0.066 13.3 1.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) IPP-2 PF04979.14 ETS86096.1 - 9.4e-24 84.6 9.9 9.4e-24 84.6 9.9 1.9 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) UvdE PF03851.14 ETS86097.1 - 4.6e-114 380.3 0.0 5.8e-114 380.0 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE SET PF00856.28 ETS86098.1 - 5e-22 79.1 0.1 1.8e-21 77.2 0.0 1.9 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 ETS86098.1 - 3.1e-07 31.1 1.3 7.9e-07 29.8 0.2 2.1 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding GST_N_2 PF13409.6 ETS86099.1 - 1.2e-18 67.1 0.1 3.1e-18 65.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ETS86099.1 - 1.5e-17 63.7 0.0 2.9e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ETS86099.1 - 1.8e-10 41.0 0.1 3.8e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS86099.1 - 1.2e-07 31.7 0.3 2.3e-07 30.7 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ETS86099.1 - 0.00052 20.2 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ETS86099.1 - 0.0016 19.0 0.0 0.0027 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ETS86099.1 - 0.033 14.4 0.0 0.068 13.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 ETS86099.1 - 0.046 13.9 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin MFS_1 PF07690.16 ETS86101.1 - 6.3e-09 35.2 22.6 6.3e-09 35.2 22.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 ETS86101.1 - 0.0037 17.0 6.0 0.0037 17.0 6.0 2.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 DUF4500 PF14937.6 ETS86101.1 - 0.2 11.7 0.5 97 3.1 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4500) Glycos_transf_1 PF00534.20 ETS86102.1 - 1.8e-12 47.1 0.0 3.2e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ETS86102.1 - 1.3e-09 38.6 0.0 2.9e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 RasGAP_C PF03836.15 ETS86103.1 - 0.023 14.8 0.1 0.039 14.1 0.1 1.3 1 0 0 1 1 1 0 RasGAP C-terminus Tape_meas_lam_C PF09718.10 ETS86104.1 - 5 7.3 12.7 0.2 11.8 2.5 3.0 1 1 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Acetyltransf_1 PF00583.25 ETS86105.1 - 1.2e-14 54.6 0.0 1.4e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS86105.1 - 3e-13 49.8 0.0 3.7e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS86105.1 - 6.5e-13 48.9 0.0 9e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETS86105.1 - 1.7e-06 28.1 0.0 4.6e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS86105.1 - 3e-05 23.9 0.1 4.3e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 ETS86105.1 - 0.00024 21.1 0.0 0.00041 20.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 ETS86105.1 - 0.0015 18.7 0.0 0.0018 18.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ETS86105.1 - 0.061 14.0 0.0 0.076 13.7 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 ETS86106.1 - 5.5e-29 101.2 29.3 5.5e-29 101.2 29.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS86106.1 - 2.2e-05 23.5 3.2 4.7e-05 22.4 2.7 1.9 1 1 0 1 1 1 1 MFS_1 like family SBP_bac_5 PF00496.22 ETS86107.1 - 5.3e-43 147.4 0.0 7.1e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle p450 PF00067.22 ETS86108.1 - 3.4e-81 273.4 0.0 4.7e-81 272.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TauD PF02668.16 ETS86109.1 - 2.2e-28 99.8 0.1 2.7e-28 99.5 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 ETS86109.1 - 0.0039 16.3 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 CsiD PEP_mutase PF13714.6 ETS86110.1 - 3e-33 115.3 0.1 3.5e-33 115.0 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 ETS86110.1 - 2.6e-18 65.8 0.1 3.5e-18 65.4 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Dynactin_p62 PF05502.13 ETS86110.1 - 0.23 10.2 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Dynactin p62 family zinc_ribbon_12 PF11331.8 ETS86111.1 - 7.4 6.5 10.2 0.46 10.3 0.1 3.8 3 1 0 3 3 3 0 Probable zinc-ribbon domain ADH_zinc_N PF00107.26 ETS86112.1 - 5.8e-23 81.3 0.2 1.1e-22 80.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS86112.1 - 8.8e-12 46.2 0.0 1.6e-11 45.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS86112.1 - 4.6e-10 39.3 0.1 3.2e-09 36.7 0.1 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Fungal_trans PF04082.18 ETS86113.1 - 1.8e-13 50.2 0.6 2.9e-13 49.5 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Orthoreo_P17 PF07272.11 ETS86113.1 - 0.17 11.9 0.4 0.3 11.1 0.4 1.3 1 0 0 1 1 1 0 Orthoreovirus P17 protein Peptidase_A4 PF01828.17 ETS86114.1 - 3e-73 245.7 10.7 3.5e-73 245.5 10.7 1.0 1 0 0 1 1 1 1 Peptidase A4 family Peptidase_S66 PF02016.15 ETS86115.1 - 2.1e-24 86.0 0.0 3e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 LD-carboxypeptidase N-terminal domain Peptidase_S66C PF17676.1 ETS86115.1 - 1.4e-21 77.3 0.0 2.1e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase C-terminal domain FAD_binding_3 PF01494.19 ETS86117.1 - 5.6e-12 45.6 0.1 1.2e-11 44.4 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ETS86117.1 - 6.5e-05 22.7 0.3 0.0075 15.9 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS86117.1 - 0.0087 16.3 0.1 0.023 14.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 ETS86117.1 - 0.047 12.7 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.14 ETS86117.1 - 0.056 12.7 0.1 0.15 11.3 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ETS86117.1 - 0.15 11.7 0.1 0.38 10.4 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thymidylate_kin PF02223.17 ETS86121.1 - 4.2e-42 143.9 0.0 9.9e-42 142.7 0.0 1.5 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.6 ETS86121.1 - 7.6e-05 23.0 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 ETS86121.1 - 0.035 13.9 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 ETS86121.1 - 0.12 12.9 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain 14-3-3 PF00244.20 ETS86123.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 14-3-3 protein DNA_pol_phi PF04931.13 ETS86123.1 - 6.5 4.7 12.0 10 4.1 12.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi PfkB PF00294.24 ETS86124.1 - 3e-14 53.0 0.0 6e-14 52.0 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase GST_N_2 PF13409.6 ETS86126.1 - 2.5e-19 69.4 0.0 4.3e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS86126.1 - 2.9e-05 24.0 0.0 0.00011 22.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ETS86126.1 - 0.013 15.9 0.0 3.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ETS86126.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain adh_short PF00106.25 ETS86127.1 - 4.3e-27 94.8 0.1 7.6e-27 94.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS86127.1 - 6.8e-20 71.6 0.3 8.3e-20 71.3 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS86127.1 - 1.7e-06 28.1 0.0 2.8e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 KR domain GTP_cyclohydroI PF01227.22 ETS86128.1 - 8.7e-75 250.1 0.6 1.2e-74 249.6 0.6 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 ETS86128.1 - 0.0044 17.2 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein OmpH PF03938.14 ETS86128.1 - 0.72 10.2 3.6 2.6 8.4 0.0 2.7 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) CMV_1a PF12467.8 ETS86128.1 - 2.2 8.6 4.8 1.2 9.5 0.4 2.4 3 0 0 3 3 3 0 Cucumber mosaic virus 1a protein family TAFII28 PF04719.14 ETS86129.1 - 1.2e-25 89.4 0.4 2.5e-25 88.4 0.4 1.5 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 ETS86129.1 - 0.13 12.5 1.5 0.17 12.2 0.1 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TNT PF14021.6 ETS86129.1 - 0.16 12.5 1.3 2.4 8.8 0.0 2.9 3 0 0 3 3 3 0 Tuberculosis necrotizing toxin Glyco_hydro_5_C PF18564.1 ETS86130.1 - 4e-20 72.1 0.0 8.4e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 ETS86130.1 - 1.6e-08 34.4 0.0 3.5e-05 23.4 0.0 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.16 ETS86131.1 - 2.1e-32 112.4 37.1 2.3e-32 112.3 28.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PetM PF08041.11 ETS86131.1 - 0.062 12.9 3.0 0.28 10.8 3.0 2.2 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 Cu-oxidase_2 PF07731.14 ETS86134.1 - 3e-43 146.9 7.2 1.3e-40 138.3 0.2 3.3 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ETS86134.1 - 1.7e-38 131.3 3.1 6.2e-38 129.5 2.1 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 ETS86134.1 - 1.1e-33 116.6 0.9 4.8e-32 111.3 0.3 2.4 2 0 0 2 2 2 1 Multicopper oxidase fn3 PF00041.21 ETS86134.1 - 0.046 14.1 0.3 15 6.0 0.0 3.2 2 0 0 2 2 2 0 Fibronectin type III domain Dioxygenase_C PF00775.21 ETS86135.1 - 3.3e-06 26.7 0.0 0.00018 21.0 0.0 2.3 1 1 0 1 1 1 1 Dioxygenase Miga PF10265.9 ETS86137.1 - 0.061 12.3 3.4 0.081 11.9 3.4 1.1 1 0 0 1 1 1 0 Mitoguardin Apt1 PF10351.9 ETS86137.1 - 3.6 6.3 7.3 4.3 6.1 7.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Methyltransf_2 PF00891.18 ETS86138.1 - 3.4e-27 95.1 0.1 7.7e-27 94.0 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase domain HTH_24 PF13412.6 ETS86138.1 - 0.0033 16.9 0.1 0.006 16.1 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Methyltransf_31 PF13847.6 ETS86138.1 - 0.0097 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain HTH_AsnC-type PF13404.6 ETS86138.1 - 0.012 15.5 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Methyltransf_25 PF13649.6 ETS86138.1 - 0.023 15.4 0.0 0.23 12.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 ETS86138.1 - 0.029 15.1 0.0 0.066 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Rsm22 PF09243.10 ETS86138.1 - 0.066 12.5 0.0 0.098 11.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 MTS PF05175.14 ETS86138.1 - 0.2 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain GMC_oxred_N PF00732.19 ETS86139.1 - 4.8e-75 252.7 0.0 6.4e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS86139.1 - 2.3e-35 122.2 0.0 4.9e-35 121.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ETS86139.1 - 9.9e-05 21.6 0.1 0.00015 20.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ETS86139.1 - 0.0069 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS86139.1 - 0.0084 15.2 0.1 0.9 8.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 ETS86139.1 - 0.011 15.0 0.0 0.028 13.7 0.0 1.6 2 0 0 2 2 2 0 Thi4 family DAO PF01266.24 ETS86139.1 - 0.053 13.1 2.9 0.13 11.8 1.5 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase PAP2 PF01569.21 ETS86140.1 - 3.8e-25 88.2 3.4 3.8e-25 88.2 3.4 1.6 2 0 0 2 2 2 1 PAP2 superfamily TNFR_16_TM PF18422.1 ETS86140.1 - 0.67 9.9 7.1 0.94 9.5 0.3 2.9 3 0 0 3 3 3 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF983 PF06170.12 ETS86140.1 - 5 7.6 7.8 8.7 6.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DUF2085 PF09858.9 ETS86140.1 - 9 6.8 6.6 3.7 8.1 1.5 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) TetR_C_14 PF17754.1 ETS86141.1 - 0.02 14.8 6.4 0.28 11.2 0.6 2.2 2 0 0 2 2 2 0 MftR C-terminal domain MFS_1 PF07690.16 ETS86142.1 - 3.8e-34 118.2 23.5 3.8e-34 118.2 23.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Myb_DNA-binding PF00249.31 ETS86143.1 - 0.0047 17.1 0.0 0.0078 16.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUP PF00674.18 ETS86143.1 - 0.097 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 DUP family DUF3283 PF11686.8 ETS86143.1 - 0.11 12.4 0.2 4.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) Mito_carr PF00153.27 ETS86144.1 - 5.8e-15 55.0 4.9 6.3e-05 22.8 0.0 4.5 3 2 0 3 3 3 3 Mitochondrial carrier protein Fer2 PF00111.27 ETS86145.1 - 2.5e-12 46.6 0.7 4.1e-12 45.9 0.7 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rrp15p PF07890.12 ETS86146.1 - 2.2e-30 105.7 7.7 2.2e-30 105.7 7.7 2.5 2 1 0 2 2 2 1 Rrp15p TauD PF02668.16 ETS86147.1 - 2.2e-44 152.2 0.6 4e-44 151.4 0.6 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 ETS86147.1 - 1.6e-05 25.5 0.0 4.3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 ETS86147.1 - 0.034 13.3 0.0 0.047 12.8 0.0 1.3 1 1 0 1 1 1 0 CsiD Glyco_hydro_61 PF03443.14 ETS86148.1 - 3.1e-60 203.7 0.1 4.9e-60 203.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 ETS86148.1 - 6.5e-09 35.6 11.8 6.5e-09 35.6 11.8 3.4 2 0 0 2 2 2 1 Fungal cellulose binding domain NPCBM_assoc PF10633.9 ETS86148.1 - 0.0053 17.0 0.6 0.36 11.1 0.0 3.0 3 0 0 3 3 3 1 NPCBM-associated, NEW3 domain of alpha-galactosidase Colipase-like PF15083.6 ETS86150.1 - 0.13 12.4 4.1 1.5 9.0 0.2 2.1 2 0 0 2 2 2 0 Colipase-like Colipase PF01114.18 ETS86150.1 - 0.26 11.0 14.7 0.21 11.3 2.5 2.4 2 0 0 2 2 2 0 Colipase, N-terminal domain Gamma-thionin PF00304.20 ETS86150.1 - 0.31 11.3 16.4 0.75 10.1 5.2 2.4 2 0 0 2 2 2 0 Gamma-thionin family ACI44 PF15270.6 ETS86150.1 - 4.6 7.5 9.0 0.66 10.2 1.5 2.1 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor Toxin_11 PF07473.11 ETS86150.1 - 5 7.3 16.3 6.6 6.9 3.7 2.6 2 0 0 2 2 2 0 Spasmodic peptide gm9a; conotoxin from Conus species Mannosyl_trans3 PF11051.8 ETS86151.1 - 2.8e-62 210.6 0.0 5.1e-37 127.7 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative Fungal_trans PF04082.18 ETS86152.1 - 0.015 14.4 0.5 0.072 12.1 0.1 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain GFO_IDH_MocA PF01408.22 ETS86153.1 - 1.1e-10 42.3 0.0 2.4e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AnkUBD PF18418.1 ETS86154.1 - 0.073 13.2 0.1 0.69 10.1 0.0 2.3 2 0 0 2 2 2 0 Ankyrin ubiquitin-binding domain ADH_zinc_N PF00107.26 ETS86155.1 - 3.6e-10 39.9 0.0 5.5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS86155.1 - 1.7e-05 24.7 0.0 6.5e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PEP_mutase PF13714.6 ETS86155.1 - 0.066 12.6 0.0 0.15 11.5 0.0 1.5 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase ADH_zinc_N_2 PF13602.6 ETS86155.1 - 0.072 14.1 0.0 0.12 13.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pec_lyase_C PF00544.19 ETS86156.1 - 4.1e-45 154.0 3.1 4.1e-45 154.0 3.1 1.5 2 0 0 2 2 2 1 Pectate lyase Sporozoite_P67 PF05642.11 ETS86156.1 - 0.18 9.8 6.3 0.24 9.4 6.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Barwin PF00967.17 ETS86156.1 - 1.1 9.1 5.6 3.3 7.6 5.6 1.8 1 0 0 1 1 1 0 Barwin family DIOX_N PF14226.6 ETS86157.1 - 9e-06 26.4 0.0 1.9e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS86157.1 - 0.00019 21.9 0.0 0.00032 21.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 ETS86159.1 - 1.1e-20 73.9 25.5 1.4e-20 73.5 25.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.8 ETS86159.1 - 4.7e-05 22.2 4.1 7.4e-05 21.6 4.1 1.3 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Sugar_tr PF00083.24 ETS86159.1 - 0.0013 17.7 9.3 0.0018 17.3 9.3 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter PTR2 PF00854.21 ETS86159.1 - 0.0016 17.4 0.8 0.0024 16.8 0.8 1.3 1 0 0 1 1 1 1 POT family Babuvirus_MP PF07234.11 ETS86159.1 - 0.044 14.0 0.1 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Movement and RNA silencing protein DUF1688 PF07958.11 ETS86160.1 - 1.4e-176 587.3 0.0 1.6e-176 587.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) 60KD_IMP PF02096.20 ETS86161.1 - 4.4e-15 56.0 2.1 7e-15 55.3 2.1 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein DUF3460 PF11943.8 ETS86161.1 - 0.019 15.2 0.1 0.047 14.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) TOM13 PF08219.11 ETS86162.1 - 1.5e-38 130.7 0.0 1.9e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.13 ETS86163.1 - 9.4e-25 87.0 0.0 1.7e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 ETS86163.1 - 9e-11 41.8 0.0 1.7e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 ETS86163.1 - 1.3e-07 31.3 0.8 2.3e-07 30.5 0.8 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 ETS86163.1 - 0.0068 16.0 0.3 0.012 15.2 0.3 1.3 1 0 0 1 1 1 1 TAP C-terminal domain DUF1524 PF07510.11 ETS86164.1 - 8.3e-10 38.7 0.0 9.9e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Gtr1_RagA PF04670.12 ETS86165.1 - 3.7e-95 317.7 0.1 4.8e-95 317.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 ETS86165.1 - 3.4e-08 33.7 0.0 6.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ETS86165.1 - 2e-07 31.1 0.0 3.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 ETS86165.1 - 2.5e-07 30.3 0.1 4.4e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 ETS86165.1 - 2.9e-07 30.2 0.0 5.8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 ETS86165.1 - 0.00011 21.5 2.1 0.11 11.7 0.3 2.8 2 1 1 3 3 3 2 G-protein alpha subunit AAA_29 PF13555.6 ETS86165.1 - 0.0042 16.8 2.1 0.035 13.8 0.2 2.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ETS86165.1 - 0.0045 16.9 0.4 0.17 11.8 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 ETS86165.1 - 0.005 17.4 0.5 0.01 16.3 0.5 1.9 1 1 0 1 1 1 1 ABC transporter DUF815 PF05673.13 ETS86165.1 - 0.007 15.5 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF87 PF01935.17 ETS86165.1 - 0.019 15.1 0.0 5.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain Ras PF00071.22 ETS86166.1 - 1.7e-31 109.0 0.1 2.1e-31 108.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS86166.1 - 4.9e-24 84.8 0.1 8.8e-24 84.0 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS86166.1 - 1.2e-06 28.0 0.0 1.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ETS86166.1 - 0.00025 20.5 0.1 0.00034 20.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 ETS86166.1 - 0.0022 16.9 0.3 0.18 10.6 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 ETS86166.1 - 0.45 9.6 2.5 0.51 9.4 0.1 2.1 2 1 1 3 3 3 0 G-protein alpha subunit SPATIAL PF15256.6 ETS86167.1 - 1.5 9.1 6.8 2.4 8.4 6.8 1.4 1 0 0 1 1 1 0 SPATIAL Macoilin PF09726.9 ETS86167.1 - 3.3 6.2 18.1 3.7 6.0 18.1 1.1 1 0 0 1 1 1 0 Macoilin family TIP120 PF08623.10 ETS86168.1 - 6.7e-69 231.0 7.8 3.6e-68 228.6 0.0 4.8 4 2 2 6 6 5 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 ETS86168.1 - 6e-17 61.8 20.7 0.0023 18.3 0.0 9.7 8 2 0 9 9 8 5 HEAT repeats HEAT PF02985.22 ETS86168.1 - 2.4e-15 55.3 19.2 0.11 12.9 0.1 10.7 13 0 0 13 13 8 4 HEAT repeat RTP1_C1 PF10363.9 ETS86168.1 - 7e-10 39.1 7.9 0.037 14.2 0.1 7.0 7 0 0 7 7 7 2 Required for nuclear transport of RNA pol II C-terminus 1 DRIM PF07539.12 ETS86168.1 - 7.5e-07 27.8 7.7 0.0046 15.3 0.2 5.2 4 1 1 5 5 5 2 Down-regulated in metastasis Cnd1 PF12717.7 ETS86168.1 - 3.3e-06 27.2 8.0 1.8 8.6 0.2 6.7 5 1 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ETS86168.1 - 4.4e-06 27.2 1.2 2.6 8.7 0.0 6.4 7 0 0 7 7 7 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 ETS86168.1 - 1.4e-05 24.9 3.2 0.5 10.1 0.0 5.3 6 0 0 6 6 6 2 rRNA processing/ribosome biogenesis Adaptin_N PF01602.20 ETS86168.1 - 8.9e-05 21.2 17.9 0.27 9.7 0.1 6.5 7 1 0 7 7 7 3 Adaptin N terminal region V-ATPase_H_C PF11698.8 ETS86168.1 - 0.00018 21.6 1.0 1.5 9.0 0.1 4.4 4 0 0 4 4 4 2 V-ATPase subunit H Cnd3 PF12719.7 ETS86168.1 - 0.0045 16.2 1.9 6.4 5.9 0.0 5.1 5 0 0 5 5 5 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 ETS86168.1 - 0.016 15.7 20.9 19 5.9 0.0 9.7 10 2 2 12 12 10 0 HEAT-like repeat Arm PF00514.23 ETS86168.1 - 0.039 14.0 1.6 22 5.2 0.0 5.3 5 0 0 5 5 4 0 Armadillo/beta-catenin-like repeat Sigma70_ner PF04546.13 ETS86168.1 - 0.057 13.3 5.7 1.2 8.9 3.9 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region VHS PF00790.19 ETS86168.1 - 0.072 12.9 0.0 3.2 7.6 0.0 3.3 3 0 0 3 3 2 0 VHS domain NinF PF05810.12 ETS86168.1 - 0.099 12.5 0.1 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 NinF protein RNA_pol_3_Rpc31 PF11705.8 ETS86168.1 - 0.13 12.5 16.3 0.23 11.7 16.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RICTOR_N PF14664.6 ETS86168.1 - 0.14 11.1 5.3 3.6 6.5 0.0 3.4 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term U3snoRNP10 PF12397.8 ETS86168.1 - 0.23 11.8 7.5 0.96 9.8 0.5 4.3 4 0 0 4 4 3 0 U3 small nucleolar RNA-associated protein 10 RasGEF_N_2 PF14663.6 ETS86168.1 - 0.4 11.1 2.9 11 6.4 0.0 4.8 6 1 0 6 6 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain YL1 PF05764.13 ETS86168.1 - 0.43 10.6 6.5 0.91 9.6 6.5 1.4 1 0 0 1 1 1 0 YL1 nuclear protein FAM176 PF14851.6 ETS86168.1 - 0.71 9.5 2.5 1.6 8.4 2.5 1.6 1 0 0 1 1 1 0 FAM176 family TFIIF_alpha PF05793.12 ETS86168.1 - 0.77 8.3 10.3 1.3 7.5 10.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RRN3 PF05327.11 ETS86168.1 - 1.6 7.1 6.8 5.5 5.4 5.3 2.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 MMS19_C PF12460.8 ETS86168.1 - 2.4 7.2 18.5 0.62 9.1 0.1 5.2 5 2 1 6 6 6 0 RNAPII transcription regulator C-terminal Nop14 PF04147.12 ETS86168.1 - 2.9 6.0 9.5 5.9 5.0 9.5 1.4 1 0 0 1 1 1 0 Nop14-like family PUL PF08324.11 ETS86168.1 - 3.4 6.8 9.4 3.5 6.8 1.4 4.2 3 1 1 4 4 4 0 PUL domain adh_short PF00106.25 ETS86169.1 - 2.6e-08 33.6 0.0 4.3e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS86169.1 - 2.9e-07 30.6 0.2 5.2e-07 29.8 0.2 1.4 1 0 0 1 1 1 1 KR domain GCV_H PF01597.19 ETS86170.1 - 4.4e-33 113.8 0.3 5.2e-33 113.5 0.3 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 ETS86170.1 - 0.032 14.2 0.1 0.05 13.6 0.1 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Porphobil_deam PF01379.20 ETS86171.1 - 7.7e-74 247.6 0.0 1.1e-73 247.1 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 ETS86171.1 - 1.2e-18 67.3 0.1 2.8e-18 66.1 0.1 1.7 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain DUF1611 PF07755.11 ETS86171.1 - 0.098 11.9 0.1 0.31 10.3 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain S-methyl_trans PF02574.16 ETS86172.1 - 4.3e-58 197.2 0.0 4.9e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Fungal_trans_2 PF11951.8 ETS86173.1 - 0.003 16.4 0.3 0.0037 16.1 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain V-SNARE PF05008.15 ETS86173.1 - 0.12 12.8 0.1 0.3 11.5 0.2 1.6 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Epimerase PF01370.21 ETS86174.1 - 3.9e-12 46.2 0.1 4e-05 23.2 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS86174.1 - 1.1e-07 31.9 0.2 1.9e-07 31.1 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ETS86174.1 - 2.4e-07 30.1 0.0 0.00011 21.3 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 ETS86174.1 - 1.2e-06 29.0 0.1 2.3e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 ETS86174.1 - 1.5e-06 27.9 0.1 2.1e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 ETS86174.1 - 0.01 15.1 0.1 0.56 9.3 0.0 2.8 2 1 0 3 3 3 0 Male sterility protein DapB_N PF01113.20 ETS86174.1 - 0.034 14.3 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 ETS86174.1 - 0.048 13.9 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 ETS86174.1 - 0.057 12.5 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ETS86174.1 - 0.17 11.2 0.1 2.2 7.6 0.0 2.3 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase Glyco_hydro_7 PF00840.20 ETS86175.1 - 4.1e-141 470.7 9.3 5.1e-141 470.3 9.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Acylphosphatase PF00708.18 ETS86176.1 - 2.9e-25 88.5 0.4 3.2e-25 88.3 0.4 1.0 1 0 0 1 1 1 1 Acylphosphatase Hep_59 PF07052.11 ETS86177.1 - 1.1e-14 55.1 0.8 1.1e-14 55.1 0.8 2.7 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 TfuA PF07812.12 ETS86177.1 - 0.049 13.4 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 TfuA-like protein FAD_binding_3 PF01494.19 ETS86178.1 - 5.7e-32 111.3 0.0 9.3e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ETS86178.1 - 1.4e-07 31.1 0.0 1.7e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS86178.1 - 1.5e-06 27.7 0.6 0.00061 19.1 0.1 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS86178.1 - 3.7e-06 27.1 0.1 1.7e-05 25.0 0.1 2.1 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS86178.1 - 4.1e-05 23.3 1.1 0.0014 18.3 0.1 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ETS86178.1 - 8.4e-05 21.8 0.5 0.0026 16.9 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.24 ETS86178.1 - 0.00014 21.3 0.5 0.015 14.6 0.0 2.5 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 ETS86178.1 - 0.0009 18.4 0.2 0.0017 17.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 ETS86178.1 - 0.0013 18.0 0.8 0.0027 16.9 0.8 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 ETS86178.1 - 0.0015 17.9 0.4 0.004 16.4 0.1 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 ETS86178.1 - 0.0018 17.1 0.2 0.03 13.0 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 ETS86178.1 - 0.01 16.4 0.1 0.075 13.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS86178.1 - 0.022 14.7 0.1 4.4 7.3 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 ETS86178.1 - 0.042 13.0 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 ETS86178.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 ETS86178.1 - 0.11 11.3 1.6 1.1 8.1 0.1 2.2 1 1 1 2 2 2 0 Tryptophan halogenase Ank_2 PF12796.7 ETS86179.1 - 7.6e-52 173.8 7.0 4.8e-12 46.3 0.1 5.8 3 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS86179.1 - 2.6e-43 145.8 4.9 4.7e-09 36.6 0.3 8.4 5 3 3 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS86179.1 - 9.5e-39 131.0 1.2 4.1e-10 39.7 0.0 8.6 6 2 4 10 10 10 5 Ankyrin repeats (many copies) Ank PF00023.30 ETS86179.1 - 1e-36 123.7 16.6 5e-06 26.7 0.0 10.7 9 2 1 10 10 10 10 Ankyrin repeat Ank_3 PF13606.6 ETS86179.1 - 7.2e-35 115.1 6.5 1.1e-05 25.4 0.0 11.9 12 1 0 12 12 12 6 Ankyrin repeat GDPD PF03009.17 ETS86180.1 - 9.4e-49 166.5 0.0 1.4e-48 165.9 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 ETS86180.1 - 3.2e-28 98.1 0.4 4.4e-15 56.0 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS86180.1 - 5.7e-20 71.4 2.4 4.4e-07 30.3 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS86180.1 - 9.5e-18 64.0 3.0 4.9e-05 23.5 0.0 5.7 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 ETS86180.1 - 6.5e-16 58.0 6.9 0.032 14.7 0.3 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 ETS86180.1 - 1.3e-15 55.9 3.7 0.041 14.4 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat SPX PF03105.19 ETS86180.1 - 2e-06 28.0 0.0 0.0015 18.5 0.0 2.5 2 0 0 2 2 2 2 SPX domain MFS_1 PF07690.16 ETS86181.1 - 2.7e-39 135.1 48.2 2.7e-39 135.1 48.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS86181.1 - 1.3e-11 44.1 12.3 1.3e-11 44.1 12.3 2.7 2 1 0 3 3 3 1 Sugar (and other) transporter PAP2_C PF14360.6 ETS86181.1 - 0.16 12.5 2.4 0.26 11.8 0.7 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Aldo_ket_red PF00248.21 ETS86182.1 - 1.1e-40 139.7 0.0 1.2e-38 133.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family PMM PF03332.13 ETS86184.1 - 5.3e-80 268.3 0.0 6.1e-80 268.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 ETS86184.1 - 0.0024 17.7 0.0 0.022 14.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GMC_oxred_C PF05199.13 ETS86185.1 - 6e-13 49.5 0.0 2.1e-12 47.8 0.0 1.9 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 ETS86185.1 - 0.00011 21.7 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase COesterase PF00135.28 ETS86187.1 - 1.4e-84 284.8 0.0 2.1e-84 284.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS86187.1 - 0.0069 16.3 1.7 0.0087 15.9 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold IDO PF01231.18 ETS86188.1 - 1.1e-05 24.5 0.0 0.00018 20.4 0.0 2.4 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase FAD_binding_4 PF01565.23 ETS86189.1 - 5.8e-25 87.7 0.0 9.8e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 ETS86189.1 - 1.8e-16 60.5 0.0 3e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain ADSL_C PF10397.9 ETS86189.1 - 0.0039 17.7 0.0 0.72 10.5 0.0 2.7 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Methyltransf_23 PF13489.6 ETS86190.1 - 7.3e-12 45.4 0.0 1.4e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS86190.1 - 8.6e-10 39.2 0.0 3.8e-09 37.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS86190.1 - 1.2e-09 38.6 0.0 1.1e-08 35.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS86190.1 - 6.8e-09 35.7 0.0 1.3e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS86190.1 - 7.3e-09 36.3 0.0 1.6e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS86190.1 - 4.5e-05 23.0 0.0 8.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 ETS86190.1 - 0.00015 21.5 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 ETS86190.1 - 0.00054 19.4 0.1 0.00082 18.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 ETS86190.1 - 0.00076 18.8 0.1 0.0011 18.3 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 ETS86190.1 - 0.024 14.1 0.0 0.05 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase TPMT PF05724.11 ETS86190.1 - 0.064 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) RrnaAD PF00398.20 ETS86190.1 - 0.073 12.1 0.0 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.18 ETS86190.1 - 0.081 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family zf-C2H2_jaz PF12171.8 ETS86191.1 - 2.6e-06 27.5 6.0 0.0096 16.2 0.9 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ETS86191.1 - 7.9e-06 26.1 3.8 0.067 13.6 0.3 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 ETS86191.1 - 0.00021 21.6 6.1 0.011 16.1 0.2 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type RNase_T PF00929.24 ETS86191.1 - 0.00048 20.7 0.0 0.0052 17.3 0.0 2.3 3 0 0 3 3 3 1 Exonuclease zf-C2H2_4 PF13894.6 ETS86191.1 - 0.003 18.2 5.1 0.49 11.4 0.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ETS86191.1 - 0.017 15.1 3.8 0.017 15.1 0.5 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger TPT PF03151.16 ETS86192.1 - 3.3e-07 30.0 1.6 4.2e-07 29.6 1.6 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family GalP_UDP_tr_C PF02744.17 ETS86193.1 - 4.8e-37 127.2 0.0 7.2e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 ETS86193.1 - 1.9e-11 44.7 0.0 3e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain ABC_tran PF00005.27 ETS86194.1 - 2e-43 148.2 0.0 7.6e-21 75.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS86194.1 - 9.4e-32 110.7 34.2 1.2e-27 97.3 13.5 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 ETS86194.1 - 5.4e-10 39.1 1.1 0.00011 21.8 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETS86194.1 - 1.3e-09 38.3 4.3 0.044 13.6 0.0 4.7 4 1 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 ETS86194.1 - 1.5e-09 37.3 0.6 0.0002 20.5 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 ETS86194.1 - 3.7e-08 33.7 0.4 0.0026 18.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ETS86194.1 - 1.3e-07 31.2 3.3 0.0059 16.3 0.3 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ETS86194.1 - 7e-07 29.3 1.2 0.011 15.6 0.1 3.2 3 0 0 3 3 3 2 RsgA GTPase AAA_23 PF13476.6 ETS86194.1 - 1e-06 29.4 1.7 0.0012 19.4 0.4 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ETS86194.1 - 1.6e-06 28.7 0.5 0.0059 17.0 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.18 ETS86194.1 - 6.9e-06 25.6 0.1 0.009 15.4 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_33 PF13671.6 ETS86194.1 - 0.00011 22.4 0.1 0.51 10.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 ETS86194.1 - 0.00012 21.7 0.3 0.13 11.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 ETS86194.1 - 0.00014 21.2 0.7 0.047 13.0 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin MMR_HSR1 PF01926.23 ETS86194.1 - 0.00028 21.0 0.1 0.73 9.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase cobW PF02492.19 ETS86194.1 - 0.00032 20.4 2.2 0.2 11.2 0.2 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 ETS86194.1 - 0.00047 20.0 0.6 0.58 9.8 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 ETS86194.1 - 0.00064 19.9 2.1 0.7 9.9 0.1 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain NTPase_1 PF03266.15 ETS86194.1 - 0.00072 19.5 0.2 0.56 10.1 0.0 2.5 2 0 0 2 2 2 1 NTPase Viral_helicase1 PF01443.18 ETS86194.1 - 0.00097 18.9 0.5 0.83 9.4 0.1 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 ETS86194.1 - 0.0011 19.0 1.2 0.62 10.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Adeno_IVa2 PF02456.15 ETS86194.1 - 0.0013 17.6 1.0 0.044 12.6 0.1 2.8 3 0 0 3 3 3 1 Adenovirus IVa2 protein AAA_30 PF13604.6 ETS86194.1 - 0.0014 18.4 0.1 0.42 10.3 0.2 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ETS86194.1 - 0.0032 18.0 0.1 3.5 8.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain DEAD PF00270.29 ETS86194.1 - 0.005 16.6 0.3 4.3 7.1 0.0 3.7 4 0 0 4 4 4 1 DEAD/DEAH box helicase AAA PF00004.29 ETS86194.1 - 0.0075 16.7 0.3 6.6 7.2 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ETS86194.1 - 0.0098 15.8 0.2 1.1 9.1 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 ETS86194.1 - 0.011 16.1 0.1 6.6 7.2 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 ETS86194.1 - 0.018 14.5 0.1 5 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 ETS86194.1 - 0.04 14.0 0.3 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Dynamin family SbcCD_C PF13558.6 ETS86194.1 - 0.047 13.9 0.6 0.88 9.9 0.2 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 ETS86194.1 - 0.06 12.1 4.9 0.28 9.9 0.0 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class CbiA PF01656.23 ETS86194.1 - 0.062 13.3 0.7 1.7 8.7 0.0 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase_2 PF01637.18 ETS86194.1 - 0.068 13.1 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 ETS86194.1 - 0.082 12.3 0.1 19 4.5 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DAP3 PF10236.9 ETS86194.1 - 0.088 12.0 1.3 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.6 ETS86194.1 - 0.1 12.6 0.3 9.2 6.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 ETS86194.1 - 0.25 10.5 0.6 13 4.8 0.1 2.7 2 1 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 ETS86194.1 - 0.27 11.2 3.6 12 5.9 0.3 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) bZIP_1 PF00170.21 ETS86195.1 - 5.1e-05 23.3 6.6 5.1e-05 23.3 6.6 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ETS86195.1 - 9.9 6.3 15.7 0.064 13.3 7.0 1.9 2 0 0 2 2 2 0 Basic region leucine zipper FMO-like PF00743.19 ETS86196.1 - 3.2e-12 45.7 0.0 3.4e-11 42.3 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ETS86196.1 - 6.7e-08 32.0 0.0 4.2e-06 26.2 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ETS86196.1 - 5.9e-07 29.6 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS86196.1 - 0.0001 21.6 0.0 0.083 12.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS86196.1 - 0.00023 20.6 0.0 0.0012 18.2 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS86196.1 - 0.00025 21.1 0.0 0.02 14.9 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding GFO_IDH_MocA PF01408.22 ETS86197.1 - 4.1e-15 56.7 0.1 6.5e-15 56.0 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF3328 PF11807.8 ETS86198.1 - 5.2e-26 91.8 0.1 7.1e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Spo7 PF03907.13 ETS86198.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Spo7-like protein DUF5394 PF17372.2 ETS86199.1 - 0.2 11.2 2.2 0.26 10.8 2.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5394) Zn_clus PF00172.18 ETS86200.1 - 7.3e-09 35.6 8.2 1.2e-08 34.9 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EamA PF00892.20 ETS86201.1 - 3e-16 59.8 31.3 5.8e-14 52.4 5.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family Patatin PF01734.22 ETS86202.1 - 4.1e-10 40.2 0.0 1e-09 38.9 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase SNF2_N PF00176.23 ETS86203.1 - 1.5e-49 168.6 0.0 2.5e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS86203.1 - 6.7e-13 49.0 0.0 1.6e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS86203.1 - 9.8e-07 28.9 0.0 2.8e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit VMA21 PF09446.10 ETS86204.1 - 2.5e-14 53.1 11.3 3.6e-14 52.6 11.3 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF1673 PF07895.11 ETS86204.1 - 0.11 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF4690 PF15756.5 ETS86204.1 - 1.6 9.3 7.4 14 6.4 0.2 2.1 1 1 1 2 2 2 0 Small Novel Rich in Cartilage DUF2406 PF10295.9 ETS86205.1 - 7.3e-22 77.8 0.4 7.3e-22 77.8 0.4 2.7 2 1 0 2 2 2 1 Uncharacterised protein (DUF2406) TFIIA PF03153.13 ETS86205.1 - 0.25 11.3 26.9 0.075 13.0 21.9 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AP-5_subunit_s1 PF15001.6 ETS86205.1 - 3.3 7.6 5.5 6.1 6.8 5.5 1.5 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 DUF3292 PF11696.8 ETS86205.1 - 5.4 5.3 8.9 8.1 4.7 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) ABC_membrane PF00664.23 ETS86206.1 - 3.4e-89 299.1 42.9 6.1e-50 170.4 10.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ETS86206.1 - 1.7e-65 219.7 0.2 3.4e-32 111.8 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ETS86206.1 - 1.2e-11 44.4 8.2 7.1e-05 22.3 2.7 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ETS86206.1 - 6.8e-09 36.3 0.6 0.00092 19.6 0.2 3.1 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 ETS86206.1 - 4.4e-08 32.4 0.5 0.01 14.6 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 ETS86206.1 - 7.9e-08 32.4 0.1 0.00077 19.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 ETS86206.1 - 9.1e-07 28.8 0.7 0.077 12.7 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 ETS86206.1 - 1e-06 29.1 0.9 0.099 12.9 0.1 3.5 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 ETS86206.1 - 1.3e-06 28.4 1.5 0.044 13.5 0.9 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ETS86206.1 - 3.3e-06 26.7 2.0 0.0032 17.2 0.4 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_5 PF07728.14 ETS86206.1 - 0.00012 22.1 0.1 0.55 10.2 0.0 3.5 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ETS86206.1 - 0.00013 21.6 0.0 0.74 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 ETS86206.1 - 0.0002 21.2 0.2 0.63 9.8 0.0 3.1 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system ATP-synt_ab PF00006.25 ETS86206.1 - 0.00029 20.6 0.0 0.62 9.7 0.0 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 ETS86206.1 - 0.0011 18.5 0.1 1.9 8.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA PF00004.29 ETS86206.1 - 0.0023 18.3 3.4 6.1 7.3 0.2 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ETS86206.1 - 0.0035 17.3 0.1 2.6 7.9 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain G-alpha PF00503.20 ETS86206.1 - 0.0075 15.5 0.2 0.38 9.8 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_23 PF13476.6 ETS86206.1 - 0.0085 16.6 12.7 1.4 9.4 8.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ETS86206.1 - 0.0088 16.6 0.0 4.8 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 ETS86206.1 - 0.013 15.7 3.3 3.5 7.9 0.5 4.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 ETS86206.1 - 0.017 14.8 0.0 3 7.4 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Roc PF08477.13 ETS86206.1 - 0.018 15.2 0.9 21 5.4 0.0 3.6 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 ETS86206.1 - 0.018 15.3 0.0 2.9 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ETS86206.1 - 0.031 14.7 0.0 13 6.2 0.0 3.1 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.6 ETS86206.1 - 0.036 14.2 0.0 2.5 8.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 ETS86206.1 - 0.037 13.4 0.0 8.5 5.6 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region NB-ARC PF00931.22 ETS86206.1 - 0.037 13.2 0.4 6.1 6.0 0.1 3.0 3 0 0 3 3 3 0 NB-ARC domain PRK PF00485.18 ETS86206.1 - 0.04 13.7 0.0 8.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Dala_Dala_lig_N PF01820.21 ETS86206.1 - 0.041 14.3 0.0 12 6.4 0.0 2.8 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus AAA_14 PF13173.6 ETS86206.1 - 0.058 13.4 0.1 11 6.1 0.0 3.4 4 0 0 4 4 3 0 AAA domain AAA_11 PF13086.6 ETS86206.1 - 0.1 12.3 0.0 5.6 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 ETS86206.1 - 0.11 11.7 0.6 9.6 5.4 0.0 3.3 4 0 0 4 4 4 0 Zeta toxin DUF87 PF01935.17 ETS86206.1 - 0.12 12.4 1.9 1.7 8.7 0.4 2.8 2 1 0 2 2 2 0 Helicase HerA, central domain G6PD_C PF02781.16 ETS86207.1 - 1.2e-115 385.7 0.0 2e-115 385.0 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 ETS86207.1 - 5.6e-60 203.0 0.0 9.9e-60 202.2 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Sulfotransfer_1 PF00685.27 ETS86207.1 - 0.12 11.8 0.1 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 Sulfotransferase domain Ribosomal_L35Ae PF01247.18 ETS86208.1 - 5.9e-42 141.7 0.2 6.7e-42 141.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 ETS86208.1 - 5.3e-05 23.4 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain PEP_hydrolase PF09370.10 ETS86209.1 - 4.7e-128 426.0 0.3 5.3e-128 425.8 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like UPF0261 PF06792.11 ETS86210.1 - 1.4e-139 465.5 1.0 2e-139 465.0 1.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) Amino_oxidase PF01593.24 ETS86211.1 - 2.5e-25 89.7 0.0 3.5e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ETS86211.1 - 5.7e-10 39.3 0.0 1.5e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS86211.1 - 1.5e-07 31.4 0.1 4.2e-06 26.6 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS86211.1 - 0.00031 21.3 0.1 0.1 13.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS86211.1 - 0.00051 19.4 0.0 0.0058 15.9 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 ETS86211.1 - 0.00053 18.9 0.0 0.00091 18.1 0.0 1.3 1 0 0 1 1 1 1 MCRA family Thi4 PF01946.17 ETS86211.1 - 0.0011 18.2 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 ETS86211.1 - 0.11 11.3 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 ETS86211.1 - 0.13 12.2 0.4 0.27 11.2 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding zf-CCCH_2 PF14608.6 ETS86212.1 - 1.5e-05 25.2 61.8 2.9e-05 24.3 12.0 5.4 5 0 0 5 5 5 3 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 ETS86212.1 - 0.0074 16.6 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) SlyX PF04102.12 ETS86212.1 - 0.15 12.7 0.3 0.51 11.0 0.2 1.9 2 0 0 2 2 2 0 SlyX Glyco_hydro_20 PF00728.22 ETS86213.1 - 2.1e-87 293.8 0.0 2.6e-87 293.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ETS86213.1 - 8.9e-22 78.2 0.0 1.6e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ETS86213.1 - 0.00011 23.0 0.1 0.039 14.7 0.1 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, domain 2 p450 PF00067.22 ETS86214.1 - 1.4e-59 202.1 0.0 2e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2205 PF10224.9 ETS86215.1 - 2.1e-36 123.8 1.3 3e-36 123.2 1.3 1.2 1 0 0 1 1 1 1 Short coiled-coil protein Fungal_trans PF04082.18 ETS86216.1 - 2.5e-15 56.2 0.1 1.1e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3716 PF12511.8 ETS86217.1 - 0.0032 17.5 10.1 0.0098 15.9 10.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3716) adh_short PF00106.25 ETS86218.1 - 2e-24 86.2 0.0 2.3e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS86218.1 - 2.3e-19 69.9 0.0 2.7e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS86218.1 - 8e-11 42.2 0.0 1.2e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ETS86218.1 - 1.1e-05 25.7 0.0 0.00024 21.3 0.1 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ETS86218.1 - 4.6e-05 23.0 0.1 0.00029 20.4 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS86218.1 - 0.0032 17.4 0.3 0.0066 16.4 0.2 1.5 2 0 0 2 2 2 1 NAD(P)H-binding 3HCDH_N PF02737.18 ETS86218.1 - 0.0068 16.3 0.1 0.01 15.7 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 ETS86218.1 - 0.026 14.1 0.1 0.04 13.5 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 ETS86218.1 - 0.17 11.2 0.0 0.67 9.3 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NMO PF03060.15 ETS86219.1 - 1.6e-32 113.2 4.7 5.8e-25 88.4 0.8 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 ETS86219.1 - 6.9e-06 25.3 1.1 0.0034 16.4 0.4 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ETS86219.1 - 0.0023 17.1 0.4 0.0035 16.5 0.4 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase FMN_dh PF01070.18 ETS86219.1 - 0.0098 15.0 1.3 0.015 14.3 1.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Peptidase_A4 PF01828.17 ETS86220.1 - 5.2e-43 147.0 6.9 5.9e-43 146.8 6.9 1.0 1 0 0 1 1 1 1 Peptidase A4 family Fungal_trans_2 PF11951.8 ETS86221.1 - 7.1e-37 127.1 1.2 1.4e-36 126.1 1.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS86221.1 - 2e-10 40.6 2.1 2e-10 40.6 2.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERG4_ERG24 PF01222.17 ETS86222.1 - 1.3e-142 475.6 20.5 1.6e-142 475.3 20.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 ETS86222.1 - 0.57 10.6 3.2 40 4.7 0.1 3.4 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Sensor PF13796.6 ETS86222.1 - 5.3 7.1 9.8 25 4.9 0.3 3.7 3 1 0 3 3 3 0 Putative sensor adh_short PF00106.25 ETS86223.1 - 1.7e-23 83.1 0.0 5.2e-22 78.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS86223.1 - 7.7e-11 42.0 0.0 1.7e-10 40.9 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS86223.1 - 9.3e-07 28.9 0.1 1.8e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS86223.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Kdo PF06293.14 ETS86223.1 - 0.19 11.1 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CFEM PF05730.11 ETS86224.1 - 0.064 13.4 8.1 0.089 12.9 8.1 1.2 1 0 0 1 1 1 0 CFEM domain Trypan_PARP PF05887.11 ETS86224.1 - 0.22 11.5 5.8 0.32 11.0 5.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DEC-1_N PF04625.13 ETS86224.1 - 0.52 9.3 2.7 0.64 9.0 2.7 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region LSR PF05624.14 ETS86224.1 - 1.2 9.2 7.3 0.16 12.0 2.6 1.9 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) AAA PF00004.29 ETS86225.1 - 1.5e-15 57.8 0.0 4e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS86225.1 - 4.5e-05 23.7 1.7 0.045 14.0 0.1 3.0 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 ETS86225.1 - 7.7e-05 23.1 0.1 0.00029 21.3 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 ETS86225.1 - 0.00074 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ETS86225.1 - 0.015 15.3 0.0 0.053 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 ETS86225.1 - 0.02 15.2 0.0 0.061 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ETS86225.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ETS86225.1 - 0.065 13.0 0.1 0.26 11.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain DUF1593 PF07632.11 ETS86226.1 - 2.4e-81 273.0 0.0 3.1e-81 272.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) Speriolin_C PF15059.6 ETS86226.1 - 0.024 14.8 0.0 0.046 13.9 0.0 1.3 1 0 0 1 1 1 0 Speriolin C-terminus TFIIB PF00382.19 ETS86227.1 - 1.1e-34 118.2 0.2 3.7e-22 78.1 0.2 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 ETS86227.1 - 1.3e-11 43.8 1.3 2.4e-11 43.0 1.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 ETS86227.1 - 0.0074 16.3 0.2 0.026 14.5 0.0 1.9 1 1 1 2 2 2 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 ETS86227.1 - 0.0084 16.2 0.0 2.6 8.2 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain HTH_Tnp_ISL3 PF13542.6 ETS86227.1 - 0.035 13.5 0.0 1.5 8.3 0.0 2.8 2 1 1 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_5 PF01022.20 ETS86227.1 - 0.12 12.2 0.0 1.4 8.8 0.0 2.6 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family DUF948 PF06103.11 ETS86227.1 - 0.14 12.5 0.0 1.7 9.0 0.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Adeno_E3_CR2 PF02439.15 ETS86228.1 - 0.0026 17.5 2.0 0.0045 16.7 2.0 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF1616 PF07760.11 ETS86228.1 - 0.11 11.8 0.5 0.15 11.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) CoA_transf_3 PF02515.17 ETS86229.1 - 1.3e-129 432.5 0.0 1.7e-129 432.2 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III COesterase PF00135.28 ETS86230.1 - 3.3e-89 300.1 0.1 4e-89 299.8 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS86230.1 - 1.1e-05 25.4 0.3 0.0037 17.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Sec8_exocyst PF04048.14 ETS86232.1 - 0.0098 15.8 0.7 0.13 12.1 0.1 2.4 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain FANCL_C PF11793.8 ETS86233.1 - 0.028 14.6 0.2 0.68 10.2 0.0 2.5 2 0 0 2 2 2 0 FANCL C-terminal domain zf-C2H2_2 PF12756.7 ETS86233.1 - 0.17 12.2 3.2 2.2 8.7 0.2 2.8 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 ETS86233.1 - 6.5 7.4 7.9 12 6.5 0.2 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 ETS86233.1 - 7.1 7.0 5.9 39 4.6 0.3 3.6 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding ApeC PF16977.5 ETS86235.1 - 0.022 14.7 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 C-terminal domain of apextrin Alpha-amylase PF00128.24 ETS86237.1 - 9.9e-113 377.1 0.0 1.5e-112 376.5 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 ETS86237.1 - 2.5e-07 30.7 0.0 6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Alpha-amylase_C PF02806.18 ETS86237.1 - 0.11 13.0 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain Sugar_tr PF00083.24 ETS86238.1 - 6.6e-87 292.2 24.1 8e-87 292.0 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS86238.1 - 4.5e-23 81.8 40.9 3.1e-20 72.4 25.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ETS86238.1 - 0.00022 20.6 3.7 0.00022 20.6 3.7 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 ETS86238.1 - 0.00088 18.2 5.1 0.0059 15.5 5.7 2.0 1 1 0 1 1 1 1 MFS_1 like family Zn_clus PF00172.18 ETS86239.1 - 5.9e-07 29.5 10.9 1e-06 28.7 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CFEM PF05730.11 ETS86240.1 - 0.00039 20.5 1.2 0.00065 19.7 1.2 1.4 1 0 0 1 1 1 1 CFEM domain NACHT PF05729.12 ETS86242.1 - 5.5e-05 23.1 0.5 0.0028 17.6 0.0 3.3 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 ETS86242.1 - 0.0044 17.4 0.0 0.021 15.2 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 ETS86242.1 - 0.025 13.8 0.3 1.1 8.3 0.0 3.2 4 0 0 4 4 4 0 NB-ARC domain AAA_18 PF13238.6 ETS86242.1 - 0.029 14.9 0.0 0.22 12.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 ETS86242.1 - 0.038 14.5 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 ETS86242.1 - 0.057 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 ETS86242.1 - 0.091 13.0 0.0 0.44 10.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ETS86242.1 - 0.098 12.4 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NAPRTase_N PF17767.1 ETS86242.1 - 0.16 12.4 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain BTB PF00651.31 ETS86243.1 - 4.5e-10 39.7 0.2 2.9e-08 33.9 0.1 2.1 1 1 1 2 2 2 2 BTB/POZ domain TauD PF02668.16 ETS86244.1 - 5.5e-41 141.1 0.8 6.9e-41 140.8 0.3 1.3 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 ETS86245.1 - 2.9e-27 95.6 24.4 2.9e-27 95.6 24.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS86245.1 - 7.9e-05 21.7 1.1 7.9e-05 21.7 1.1 2.3 2 1 1 3 3 3 1 MFS_1 like family DUF1459 PF07312.11 ETS86245.1 - 0.033 14.4 0.2 0.34 11.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) Nod_GRP PF07806.11 ETS86245.1 - 0.49 10.3 2.3 1.5 8.7 2.3 1.8 1 0 0 1 1 1 0 Nodule-specific GRP repeat MFS_1 PF07690.16 ETS86246.1 - 2.9e-16 59.4 50.0 2.2e-09 36.7 23.0 4.0 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 ETS86246.1 - 2.2e-10 39.6 14.1 3.7e-10 38.9 14.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UPF0542 PF15086.6 ETS86246.1 - 3.4 7.7 7.7 7.3 6.6 0.0 4.3 5 0 0 5 5 5 0 Uncharacterised protein family UPF0542 LIP PF03583.14 ETS86247.1 - 9.3e-51 172.8 0.0 1.2e-50 172.5 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase AAA PF00004.29 ETS86249.1 - 6.4e-16 59.0 0.0 1.7e-15 57.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS86249.1 - 0.00021 21.6 0.4 0.0044 17.3 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS86249.1 - 0.00029 21.3 0.0 0.00071 20.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Zot PF05707.12 ETS86249.1 - 0.00034 20.3 0.0 0.014 15.0 0.0 2.4 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_5 PF07728.14 ETS86249.1 - 0.0025 17.8 0.0 0.0058 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 ETS86249.1 - 0.018 14.8 0.1 0.066 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 ETS86249.1 - 0.031 14.4 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 Torsin DDE_Tnp_1_2 PF13586.6 ETS86249.1 - 0.05 14.0 0.6 0.18 12.2 0.2 2.2 2 1 0 2 2 1 0 Transposase DDE domain AAA_11 PF13086.6 ETS86249.1 - 0.059 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ETS86249.1 - 0.065 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ETS86249.1 - 0.072 12.8 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Vps36_ESCRT-II PF11605.8 ETS86249.1 - 0.14 12.3 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 TSC22 PF01166.18 ETS86249.1 - 0.21 11.9 1.2 0.59 10.5 0.6 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family GMC_oxred_C PF05199.13 ETS86250.1 - 9.9e-27 94.2 0.0 1.8e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 ETS86250.1 - 3.1e-23 82.6 0.0 2.2e-22 79.8 0.0 2.2 2 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 ETS86250.1 - 8e-05 22.0 0.0 0.001 18.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS86250.1 - 0.013 15.7 0.1 0.034 14.4 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS86250.1 - 0.031 13.4 0.0 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 ETS86250.1 - 0.047 12.9 0.0 5.9 6.0 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS86250.1 - 0.14 11.4 2.4 0.35 10.1 0.9 2.0 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 ETS86250.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein CFEM PF05730.11 ETS86251.1 - 1.4e-12 47.5 11.8 2.2e-12 46.9 11.8 1.3 1 0 0 1 1 1 1 CFEM domain RTA1 PF04479.13 ETS86253.1 - 3.2e-73 245.7 8.1 3.2e-73 245.7 8.1 1.7 1 1 1 2 2 2 1 RTA1 like protein COX2_TM PF02790.15 ETS86253.1 - 7.7 6.7 9.9 0.54 10.4 0.6 3.1 4 0 0 4 4 4 0 Cytochrome C oxidase subunit II, transmembrane domain Glyco_hydro_3_C PF01915.22 ETS86254.1 - 6.7e-46 156.8 0.0 1e-45 156.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS86254.1 - 3.1e-36 125.4 0.0 5.3e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS86254.1 - 6.7e-25 87.0 0.0 1.3e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain AA_permease PF00324.21 ETS86255.1 - 3e-116 388.9 36.3 3.7e-116 388.6 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS86255.1 - 4.3e-30 104.9 42.1 5.2e-30 104.6 42.1 1.0 1 0 0 1 1 1 1 Amino acid permease Pro_racemase PF05544.11 ETS86256.1 - 5.1e-81 272.2 0.0 5.9e-81 272.0 0.0 1.0 1 0 0 1 1 1 1 Proline racemase PhzC-PhzF PF02567.16 ETS86256.1 - 0.0058 16.1 0.8 0.063 12.7 0.0 2.1 2 0 0 2 2 2 1 Phenazine biosynthesis-like protein FeS PF04060.13 ETS86256.1 - 2.3 8.0 4.0 0.51 10.0 0.1 1.9 3 0 0 3 3 3 0 Putative Fe-S cluster HMG_box_2 PF09011.10 ETS86257.1 - 0.064 13.9 0.5 0.13 12.9 0.5 1.5 1 0 0 1 1 1 0 HMG-box domain HMG_box PF00505.19 ETS86257.1 - 0.091 13.2 0.2 0.22 12.0 0.2 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box PetL PF05115.14 ETS86258.1 - 0.073 13.1 1.1 0.073 13.1 1.1 1.8 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) Aldo_ket_red PF00248.21 ETS86259.1 - 4.2e-44 150.9 0.0 2.5e-43 148.4 0.0 1.8 2 0 0 2 2 2 1 Aldo/keto reductase family Ribonuc_L-PSP PF01042.21 ETS86259.1 - 2.4e-16 59.9 0.0 7e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 Endoribonuclease L-PSP Glyco_transf_28 PF03033.20 ETS86260.1 - 3.6e-22 78.9 0.0 1.8e-21 76.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 ETS86260.1 - 1.6e-05 24.0 0.0 2.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PsbW PF07123.12 ETS86260.1 - 0.21 11.6 0.4 0.48 10.4 0.4 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) COesterase PF00135.28 ETS86261.1 - 7.9e-76 256.0 0.0 1.1e-75 255.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS86261.1 - 3.9e-06 26.9 0.2 3.5e-05 23.7 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ETS86261.1 - 5.1e-06 25.6 0.0 8.5e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 ETS86261.1 - 0.05 12.5 0.0 0.093 11.6 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme PD40 PF07676.12 ETS86262.1 - 6.2e-12 45.1 1.7 0.0084 16.0 0.0 5.5 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Amidohydro_1 PF01979.20 ETS86262.1 - 4.1e-11 42.8 0.1 3.2e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 ETS86262.1 - 1e-10 41.7 0.3 0.00037 20.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 ETS86263.1 - 1.5e-37 129.7 0.7 2e-37 129.3 0.7 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS86263.1 - 1.1e-12 48.2 3.2 8e-08 32.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.16 ETS86264.1 - 2.5e-31 108.9 25.2 2.5e-31 108.9 25.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 ETS86265.1 - 1.7e-09 37.1 22.6 5.6e-08 32.1 21.0 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ETS86265.1 - 2.3 6.4 5.2 13 3.9 0.2 2.8 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Pyr_redox_3 PF13738.6 ETS86267.1 - 1.1e-17 64.2 0.0 3.5e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS86267.1 - 5.6e-17 61.9 0.0 3.2e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS86267.1 - 4.6e-10 39.2 0.2 1.9e-08 33.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 ETS86267.1 - 1.4e-09 37.0 0.0 1.1e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.19 ETS86267.1 - 2e-05 24.0 0.1 0.048 12.9 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 ETS86267.1 - 0.00058 20.4 0.1 0.22 12.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ETS86267.1 - 0.038 13.0 0.2 0.39 9.7 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 ETS86267.1 - 0.065 12.8 0.6 24 4.4 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS86267.1 - 0.077 13.2 0.0 0.27 11.5 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Scytalone_dh PF02982.14 ETS86269.1 - 1.8e-38 131.8 0.1 2.2e-38 131.6 0.1 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 ETS86269.1 - 1.2e-09 38.3 0.1 1.5e-09 38.0 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.16 ETS86270.1 - 2.3e-28 99.2 17.3 2.3e-28 99.2 17.3 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS86270.1 - 1.7e-11 43.7 8.0 1.7e-11 43.7 8.0 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 ETS86270.1 - 4.3e-05 22.1 3.6 6.9e-05 21.5 3.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 ETS86270.1 - 0.0061 15.5 7.1 0.092 11.6 7.1 2.7 1 1 0 1 1 1 1 MFS_1 like family Tannase PF07519.11 ETS86271.1 - 3.8e-102 342.6 2.8 5.2e-102 342.2 2.8 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 ETS86271.1 - 0.076 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CT_A_B PF02626.15 ETS86272.1 - 2.1e-76 257.0 0.0 4.2e-76 256.1 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 ETS86272.1 - 5.2e-56 189.5 0.0 1.1e-55 188.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ETS86272.1 - 2.1e-34 118.3 0.1 5.3e-34 117.1 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ETS86272.1 - 9.1e-30 102.9 0.0 1.8e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CT_C_D PF02682.16 ETS86272.1 - 6e-23 81.6 0.0 1.5e-22 80.4 0.0 1.7 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_lipoyl PF00364.22 ETS86272.1 - 1.7e-06 27.8 0.8 1.9e-05 24.4 0.8 2.6 1 1 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ETS86272.1 - 2.7e-06 27.1 0.0 5.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 ETS86272.1 - 0.00025 20.8 0.7 0.034 14.0 0.0 3.0 2 1 1 3 3 3 1 Biotin-lipoyl like ATP-grasp PF02222.22 ETS86272.1 - 0.0013 18.3 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 ETS86272.1 - 0.01 15.5 0.0 0.033 13.8 0.0 1.9 1 1 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 ETS86272.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain LamB_YcsF PF03746.16 ETS86273.1 - 3.6e-83 278.9 0.0 4.4e-83 278.6 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family Aa_trans PF01490.18 ETS86274.1 - 2e-18 66.3 33.2 2.5e-18 66.0 33.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 ETS86274.1 - 0.00037 19.4 28.0 0.00037 19.4 28.0 2.3 1 1 1 2 2 2 1 Amino acid permease Amidase PF01425.21 ETS86275.1 - 3.6e-87 293.2 0.3 4.7e-87 292.8 0.3 1.1 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.16 ETS86276.1 - 4.9e-29 101.4 57.7 3.9e-17 62.2 29.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS86276.1 - 7.8e-05 21.4 32.4 0.0046 15.6 8.7 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein Ferritin_2 PF13668.6 ETS86278.1 - 6.9e-06 26.3 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain COesterase PF00135.28 ETS86279.1 - 2.5e-72 244.4 0.8 1.5e-58 199.0 0.9 2.2 1 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS86279.1 - 0.00049 20.0 0.1 0.00091 19.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ldh_1_N PF00056.23 ETS86280.1 - 2.7e-42 144.2 0.1 3.7e-42 143.7 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ETS86280.1 - 4.9e-41 140.5 0.0 6.6e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 ETS86280.1 - 2e-05 23.8 0.0 2.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 ETS86280.1 - 0.0018 17.9 0.4 1.6 8.3 0.0 2.2 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase NAD_binding_10 PF13460.6 ETS86280.1 - 0.052 13.4 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 ETS86280.1 - 0.071 12.4 0.1 0.29 10.4 0.1 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 ETS86281.1 - 7.7e-52 175.2 0.0 1.1e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS86281.1 - 6.5e-21 74.4 0.0 7.9e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ETS86281.1 - 0.00066 19.9 0.1 0.0013 18.9 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sugar_tr PF00083.24 ETS86282.1 - 4.7e-96 322.4 19.0 5.6e-96 322.2 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS86282.1 - 3.4e-23 82.2 37.7 1.7e-22 79.9 28.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ETS86282.1 - 8.2e-06 24.5 2.6 1.5e-05 23.6 2.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2207 PF09972.9 ETS86283.1 - 2.2 6.9 8.6 7.7 5.1 0.1 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Zn_clus PF00172.18 ETS86284.1 - 1.1e-07 31.8 7.2 1.1e-07 31.8 7.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS86284.1 - 0.071 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Fungal_trans PF04082.18 ETS86285.1 - 8.3e-24 84.0 0.0 1.4e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS86285.1 - 6e-11 42.3 12.4 1.1e-10 41.5 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain K_trans PF02705.16 ETS86286.1 - 3.1e-182 606.8 18.7 3.6e-182 606.6 18.7 1.0 1 0 0 1 1 1 1 K+ potassium transporter DUF485 PF04341.12 ETS86286.1 - 1.3 9.0 5.7 60 3.7 0.0 3.8 2 1 1 3 3 3 0 Protein of unknown function, DUF485 Pkinase PF00069.25 ETS86287.1 - 1.2e-49 169.1 0.0 1.7e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS86287.1 - 9.5e-27 93.9 0.0 1.2e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ETS86287.1 - 0.00014 21.9 0.0 0.0005 20.1 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETS86287.1 - 0.00055 19.6 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 ETS86287.1 - 0.002 17.5 0.0 0.0055 16.1 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 ETS86287.1 - 0.0023 17.3 0.0 0.0055 16.1 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ETS86287.1 - 0.0062 16.2 0.0 0.018 14.6 0.0 1.7 1 1 0 1 1 1 1 RIO1 family TrkH PF02386.16 ETS86288.1 - 2e-129 432.3 4.4 6.5e-127 424.0 1.5 2.0 2 0 0 2 2 2 2 Cation transport protein Acyl_transf_3 PF01757.22 ETS86289.1 - 4.9e-16 58.7 22.2 8.4e-16 57.9 22.2 1.5 1 1 0 1 1 1 1 Acyltransferase family E1-E2_ATPase PF00122.20 ETS86290.1 - 1e-37 129.4 16.6 3.6e-31 108.1 0.3 3.7 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 ETS86290.1 - 3.4e-26 92.1 8.0 3.4e-26 92.1 8.0 2.7 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ETS86290.1 - 2.1e-18 67.4 0.0 7.5e-15 55.8 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ETS86290.1 - 6.8e-18 64.5 0.0 2.3e-17 62.8 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ETS86290.1 - 4.1e-17 61.6 0.1 4.1e-17 61.6 0.1 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ETS86290.1 - 0.0022 17.8 0.2 0.0099 15.6 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HET PF06985.11 ETS86291.1 - 2.1e-24 86.6 0.3 4.8e-24 85.4 0.1 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.7 ETS86292.1 - 0.00039 20.2 0.2 0.0012 18.6 0.0 1.9 2 0 0 2 2 2 1 F-box-like GATase PF00117.28 ETS86293.1 - 0.0029 17.4 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Lactonase PF10282.9 ETS86295.1 - 2.1e-09 37.1 0.5 0.043 13.1 0.0 3.5 2 2 1 3 3 3 3 Lactonase, 7-bladed beta-propeller NHL PF01436.21 ETS86295.1 - 0.0005 20.0 0.0 2 8.6 0.0 4.0 4 0 0 4 4 4 2 NHL repeat Cu-oxidase PF00394.22 ETS86295.1 - 0.0055 16.8 0.2 0.009 16.1 0.2 1.3 1 0 0 1 1 1 1 Multicopper oxidase MARVEL PF01284.23 ETS86299.1 - 5.9e-09 36.1 6.7 8.1e-09 35.7 6.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF5090 PF17009.5 ETS86299.1 - 0.018 15.0 1.8 5.6 6.9 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5090) FA_desaturase PF00487.24 ETS86299.1 - 3 7.6 7.4 0.34 10.7 2.6 1.6 1 1 1 2 2 2 0 Fatty acid desaturase PAN_1 PF00024.26 ETS86300.1 - 0.00052 19.9 0.0 0.00098 19.0 0.0 1.3 1 0 0 1 1 1 1 PAN domain Fringe PF02434.16 ETS86300.1 - 0.0022 17.5 0.1 0.0058 16.1 0.1 1.7 1 1 0 1 1 1 1 Fringe-like PAN_3 PF08277.12 ETS86300.1 - 0.018 14.9 0.4 0.032 14.0 0.4 1.4 1 0 0 1 1 1 0 PAN-like domain Galactosyl_T PF01762.21 ETS86300.1 - 0.044 13.6 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Galactosyltransferase DUF5020 PF16412.5 ETS86300.1 - 0.071 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5020) RNase_H PF00075.24 ETS86302.1 - 6e-20 71.9 0.0 9.4e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 ETS86302.1 - 0.003 17.3 0.0 2.3 8.0 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase-like Alpha-L-AF_C PF06964.12 ETS86304.1 - 6e-22 78.6 0.0 9e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 ETS86304.1 - 0.027 14.7 0.6 0.092 13.0 0.6 2.0 1 1 0 1 1 1 0 Carbohydrate binding domain Aldo_ket_red PF00248.21 ETS86305.1 - 1.6e-70 237.7 0.0 1.9e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cupin_2 PF07883.11 ETS86306.1 - 8.9e-09 34.9 0.1 0.00021 20.9 0.1 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 ETS86306.1 - 0.0013 18.4 0.0 0.8 9.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_1 PF00190.22 ETS86306.1 - 0.0025 17.5 0.1 0.18 11.4 0.0 2.4 2 0 0 2 2 2 1 Cupin Cupin_6 PF12852.7 ETS86306.1 - 0.0066 16.2 0.0 4.3 7.0 0.0 2.3 2 0 0 2 2 2 2 Cupin EutQ PF06249.12 ETS86306.1 - 0.027 14.3 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ AraC_binding PF02311.19 ETS86306.1 - 0.052 13.5 0.0 5.1 7.0 0.0 2.2 2 0 0 2 2 2 0 AraC-like ligand binding domain Histone_H2A_C PF16211.5 ETS86306.1 - 0.16 11.7 0.1 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 C-terminus of histone H2A Nitroreductase PF00881.24 ETS86307.1 - 2.4e-31 109.0 0.0 6.1e-31 107.8 0.0 1.6 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ETS86307.1 - 1.4e-11 44.4 0.1 7.4e-05 22.4 0.0 3.1 2 1 1 3 3 3 3 Putative TM nitroreductase DUF3099 PF11298.8 ETS86308.1 - 0.35 11.0 2.0 1.4 9.1 2.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) ArsB PF02040.15 ETS86309.1 - 2.4e-14 53.5 19.4 9.9e-11 41.6 6.5 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein ATP11 PF06644.11 ETS86309.1 - 3.7 7.3 6.4 6.7 6.4 6.4 1.5 1 0 0 1 1 1 0 ATP11 protein ThrE PF06738.12 ETS86310.1 - 4.6e-61 206.3 27.3 8.8e-59 198.8 7.6 2.7 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ETS86310.1 - 4.9e-08 33.2 11.5 4.9e-08 33.2 11.5 3.0 3 0 0 3 3 3 1 Threonine/Serine exporter, ThrE SNF2_N PF00176.23 ETS86311.1 - 1.1e-57 195.4 0.0 1.7e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS86311.1 - 2.1e-12 47.4 0.0 7.3e-12 45.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain APH PF01636.23 ETS86311.1 - 3.1e-11 43.7 0.3 7.6e-11 42.4 0.3 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ETS86311.1 - 1.2e-06 28.1 0.0 3.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Ecdysteroid kinase ResIII PF04851.15 ETS86311.1 - 3.2e-06 27.2 0.0 7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Choline_kinase PF01633.20 ETS86311.1 - 9.6e-06 25.3 0.0 2.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 ETS86311.1 - 0.028 13.6 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase DUF1679 PF07914.11 ETS86311.1 - 0.04 12.8 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) SWI2_SNF2 PF18766.1 ETS86311.1 - 0.11 12.1 0.0 1.4 8.6 0.0 2.5 2 1 1 3 3 3 0 SWI2/SNF2 ATPase NACHT PF05729.12 ETS86312.1 - 1e-05 25.6 2.1 3e-05 24.0 0.4 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 ETS86312.1 - 0.00011 22.7 0.2 0.00011 22.7 0.2 3.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 ETS86312.1 - 0.0079 16.5 1.3 2.7 8.3 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 ETS86312.1 - 0.011 16.2 1.0 3.9 7.9 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 ETS86312.1 - 0.013 15.9 0.0 0.063 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ETS86312.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 ETS86313.1 - 1.7e-25 89.7 0.0 6.2e-24 84.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 AMP-binding PF00501.28 ETS86314.1 - 2.9e-59 200.8 0.0 3.5e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS86314.1 - 2.9e-15 57.0 0.0 6.3e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyridoxal_deC PF00282.19 ETS86315.1 - 1.6e-73 247.6 0.0 1.8e-73 247.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain OKR_DC_1 PF01276.20 ETS86315.1 - 0.01 14.6 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 ETS86315.1 - 0.036 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family HAP1_N PF04849.13 ETS86315.1 - 0.17 11.1 0.0 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DUF3176 PF11374.8 ETS86316.1 - 1.8e-34 118.1 0.1 9.8e-34 115.8 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) p450 PF00067.22 ETS86318.1 - 9.2e-30 103.8 0.0 1e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 LcrG PF07216.12 ETS86318.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 LcrG protein zf-C2H2 PF00096.26 ETS86319.1 - 3.6e-05 24.0 6.4 0.0088 16.5 0.7 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type Nop14 PF04147.12 ETS86319.1 - 0.00022 19.6 14.4 0.00027 19.3 14.4 1.2 1 0 0 1 1 1 1 Nop14-like family zf-C2H2_4 PF13894.6 ETS86319.1 - 0.0029 18.3 4.5 0.86 10.6 0.6 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ETS86319.1 - 0.096 12.5 6.5 2.1 8.2 0.6 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type GramPos_pilinD1 PF16555.5 ETS86319.1 - 0.23 11.6 4.9 0.31 11.2 4.9 1.1 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain SDA1 PF05285.12 ETS86319.1 - 0.44 9.9 26.4 0.53 9.7 26.4 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 ETS86319.1 - 2.5 7.3 30.2 3.4 6.9 30.2 1.1 1 0 0 1 1 1 0 BUD22 LAP1C PF05609.12 ETS86319.1 - 2.6 7.1 11.6 3.1 6.8 11.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Zip PF02535.22 ETS86319.1 - 2.8 7.1 5.7 3.6 6.7 5.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Lin-8 PF03353.15 ETS86319.1 - 8.2 5.9 13.7 11 5.5 13.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ABC_tran PF00005.27 ETS86320.1 - 4.3e-53 179.5 0.0 2e-26 93.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS86320.1 - 7.6e-34 117.6 21.2 1.6e-28 100.1 0.5 3.5 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 ETS86320.1 - 1e-10 41.5 0.5 0.0072 15.8 0.0 4.1 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 ETS86320.1 - 2.5e-07 31.0 0.0 0.024 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ETS86320.1 - 3.3e-07 30.4 0.1 0.0059 16.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ETS86320.1 - 8.3e-07 29.4 0.3 0.076 13.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ETS86320.1 - 2.6e-06 27.1 0.1 0.026 14.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 ETS86320.1 - 2.9e-06 27.5 0.7 0.074 13.1 0.1 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_21 PF13304.6 ETS86320.1 - 9.8e-06 25.6 0.1 0.043 13.6 0.0 3.3 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ETS86320.1 - 1.4e-05 25.5 0.0 0.031 14.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 ETS86320.1 - 1.9e-05 24.7 0.5 0.055 13.6 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 ETS86320.1 - 2.6e-05 24.8 0.0 0.033 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 ETS86320.1 - 0.00013 21.4 0.1 0.13 11.5 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SSE PF00437.20 ETS86320.1 - 0.00021 20.4 0.1 0.13 11.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Dynamin_N PF00350.23 ETS86320.1 - 0.00034 20.7 0.4 0.072 13.2 0.0 2.7 2 0 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.12 ETS86320.1 - 0.0006 19.2 0.1 0.22 10.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 ETS86320.1 - 0.0012 19.4 0.2 0.19 12.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ETS86320.1 - 0.0019 18.5 0.0 4.7 7.7 0.0 3.4 3 0 0 3 3 3 0 RNA helicase NACHT PF05729.12 ETS86320.1 - 0.002 18.1 1.5 0.51 10.2 0.1 2.8 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 ETS86320.1 - 0.0058 16.4 0.6 2.1 8.0 0.1 3.1 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 ETS86320.1 - 0.0058 16.4 0.0 1.5 8.5 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase cobW PF02492.19 ETS86320.1 - 0.0067 16.0 1.0 0.35 10.4 0.2 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 ETS86320.1 - 0.018 14.6 0.1 4.5 6.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ETS86320.1 - 0.021 14.4 0.4 3.9 7.0 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NB-ARC PF00931.22 ETS86320.1 - 0.022 14.0 0.8 0.96 8.6 0.1 2.5 2 1 0 2 2 2 0 NB-ARC domain SbcCD_C PF13558.6 ETS86320.1 - 0.024 14.9 0.1 0.5 10.6 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 ETS86320.1 - 0.037 14.0 0.1 8.1 6.5 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 ETS86320.1 - 0.044 13.8 0.0 6.3 6.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 ETS86320.1 - 0.044 13.7 0.2 7 6.5 0.0 3.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Septin PF00735.18 ETS86320.1 - 0.048 12.9 0.6 9.8 5.4 0.0 3.2 4 0 0 4 4 3 0 Septin Adeno_IVa2 PF02456.15 ETS86320.1 - 0.069 11.9 0.1 1.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein IstB_IS21 PF01695.17 ETS86320.1 - 0.077 12.7 0.9 15 5.3 0.1 3.2 4 0 0 4 4 3 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 ETS86320.1 - 0.091 12.5 0.3 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.6 ETS86320.1 - 0.096 12.4 0.0 7.2 6.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.27 ETS86320.1 - 0.12 11.9 0.0 17 4.9 0.0 2.7 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain Rad17 PF03215.15 ETS86320.1 - 0.14 12.0 0.1 30 4.5 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 ETS86320.1 - 0.16 11.7 0.0 17 5.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ETS86320.1 - 0.19 11.6 0.6 21 5.0 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.6 ETS86320.1 - 0.21 11.9 0.2 11 6.3 0.2 2.7 2 0 0 2 2 2 0 AAA domain PS-DH PF14765.6 ETS86321.1 - 4.5e-61 206.7 0.1 7.2e-61 206.0 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ETS86321.1 - 5.9e-59 200.1 0.3 1.1e-58 199.3 0.3 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 ETS86321.1 - 1.5e-58 197.7 0.8 2.8e-58 196.8 0.1 2.0 2 0 0 2 2 1 1 KR domain ketoacyl-synt PF00109.26 ETS86321.1 - 2.1e-56 191.4 0.9 3.7e-56 190.5 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ETS86321.1 - 2.4e-28 98.5 0.1 5.8e-28 97.3 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ETS86321.1 - 1.5e-20 73.8 0.0 6e-20 71.8 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ETS86321.1 - 5.2e-17 62.3 0.0 1.4e-16 61.0 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 ETS86321.1 - 5.7e-14 53.3 0.0 4.5e-13 50.4 0.0 2.6 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ETS86321.1 - 1.4e-13 51.0 0.1 9.6e-13 48.2 0.1 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 ETS86321.1 - 2e-12 47.6 0.0 1e-11 45.4 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS86321.1 - 4.8e-12 46.0 0.0 1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS86321.1 - 3.6e-11 43.1 0.0 1.3e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS86321.1 - 2.6e-10 40.8 0.0 1.6e-09 38.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 ETS86321.1 - 6.8e-09 36.0 0.3 1.9e-08 34.6 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 ETS86321.1 - 2.4e-07 30.4 0.0 7.9e-07 28.7 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N PF08240.12 ETS86321.1 - 2.9e-05 23.9 0.7 7.4e-05 22.6 0.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_PK PF05891.12 ETS86321.1 - 0.00093 18.8 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Ubie_methyltran PF01209.18 ETS86321.1 - 0.0053 16.1 0.0 0.046 13.1 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 ETS86321.1 - 0.022 13.9 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent 3Beta_HSD PF01073.19 ETS86321.1 - 0.027 13.5 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_24 PF13578.6 ETS86321.1 - 0.037 15.0 0.0 0.16 13.0 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain DSPc PF00782.20 ETS86321.1 - 0.12 12.1 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Methyltransf_16 PF10294.9 ETS86321.1 - 0.13 11.9 0.0 0.56 9.9 0.0 2.1 2 0 0 2 2 2 0 Lysine methyltransferase GST_C_6 PF17171.4 ETS86321.1 - 0.14 12.0 0.0 9.5 6.1 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain p450 PF00067.22 ETS86322.1 - 2.1e-61 208.1 0.0 3.6e-61 207.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.13 ETS86323.1 - 9.5e-16 58.3 0.0 2.3e-15 57.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS86323.1 - 2.7e-07 31.4 4.5 3.3e-07 31.1 4.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 ETS86323.1 - 1.1e-06 27.7 0.0 1.7e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 ETS86323.1 - 2e-06 27.4 0.0 0.00055 19.5 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ETS86323.1 - 2.9e-05 23.5 0.0 0.00044 19.6 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 ETS86323.1 - 0.00075 19.4 0.0 0.15 11.8 0.0 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase COesterase PF00135.28 ETS86323.1 - 0.016 14.1 0.0 0.041 12.8 0.0 1.6 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_1 PF00561.20 ETS86323.1 - 0.11 12.2 1.3 1.2 8.7 0.0 2.5 2 1 0 3 3 3 0 alpha/beta hydrolase fold AMP-binding PF00501.28 ETS86324.1 - 0 1238.9 0.3 3.1e-78 263.3 0.0 5.4 5 0 0 5 5 5 5 AMP-binding enzyme Condensation PF00668.20 ETS86324.1 - 2.4e-185 616.6 0.0 5.6e-38 130.8 0.0 6.4 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.25 ETS86324.1 - 1.3e-64 214.4 8.6 5.3e-11 42.7 0.0 7.6 7 0 0 7 7 7 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ETS86324.1 - 7.8e-06 26.8 0.0 8.5 7.4 0.0 5.6 5 0 0 5 5 5 3 AMP-binding enzyme C-terminal domain HLH PF00010.26 ETS86325.1 - 2.6e-05 24.1 0.1 0.00011 22.0 0.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain dsDNA_bind PF01984.20 ETS86325.1 - 1.2 9.5 6.4 14 6.0 0.1 2.5 1 1 1 2 2 2 0 Double-stranded DNA-binding domain Mucin PF01456.17 ETS86325.1 - 2.2 8.3 11.9 1.4 8.9 8.4 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein HLH PF00010.26 ETS86326.1 - 1.3e-06 28.3 0.1 6.9e-06 25.9 0.1 2.1 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Spt5_N PF11942.8 ETS86326.1 - 0.0013 19.7 0.4 0.0027 18.7 0.4 1.5 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal THP2 PF09432.10 ETS86326.1 - 0.0085 16.1 0.1 0.015 15.4 0.1 1.3 1 0 0 1 1 1 1 Tho complex subunit THP2 Takusan PF04822.13 ETS86326.1 - 0.019 14.8 0.0 0.05 13.5 0.0 1.7 1 0 0 1 1 1 0 Takusan Aminotran_1_2 PF00155.21 ETS86327.1 - 5.5e-07 29.1 0.0 5.7e-07 29.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Methyltransf_11 PF08241.12 ETS86328.1 - 6.3e-12 46.0 0.0 2.2e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS86328.1 - 3.6e-11 43.6 0.0 2.1e-10 41.2 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS86328.1 - 1.6e-08 34.5 0.0 2.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS86328.1 - 1.9e-07 30.7 0.0 2.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ETS86328.1 - 3.1e-07 31.1 0.0 1.4e-06 29.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Pyr_redox_2 PF07992.14 ETS86328.1 - 9.6e-05 21.8 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.6 ETS86328.1 - 0.002 18.0 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS86328.1 - 0.0038 16.8 0.0 0.0093 15.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 ETS86328.1 - 0.019 14.4 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Aminotran_3 PF00202.21 ETS86329.1 - 7.1e-91 304.9 0.0 9.3e-91 304.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aspzincin_M35 PF14521.6 ETS86330.1 - 1.8e-25 90.1 0.5 2.8e-25 89.6 0.5 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase E1-E2_ATPase PF00122.20 ETS86331.1 - 3.6e-51 173.3 2.6 3.6e-51 173.3 2.6 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ETS86331.1 - 2.2e-20 73.8 0.1 4e-20 73.0 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 ETS86331.1 - 3.3e-05 24.2 0.1 9.1e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 ETS86331.1 - 0.00041 20.2 0.5 0.039 13.7 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ETS86331.1 - 0.15 12.4 0.0 0.44 10.9 0.0 1.8 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Flavin_Reduct PF01613.18 ETS86332.1 - 5.3e-16 59.0 0.0 7.9e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Glyco_hydro_18 PF00704.28 ETS86333.1 - 7.7e-90 301.8 10.4 9e-90 301.6 10.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 FMN_bind PF04205.14 ETS86333.1 - 0.0021 18.6 0.5 0.16 12.6 0.0 2.5 2 0 0 2 2 2 1 FMN-binding domain TSA PF03249.13 ETS86334.1 - 0.34 9.7 0.1 0.53 9.0 0.1 1.3 1 0 0 1 1 1 0 Type specific antigen TetR_C_28 PF17937.1 ETS86334.1 - 1 9.9 6.9 7.4 7.1 0.1 2.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain TPR_12 PF13424.6 ETS86336.1 - 1.5e-25 89.3 18.1 2e-12 47.2 1.2 6.3 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 ETS86336.1 - 2.2e-22 78.2 10.9 2.1e-06 27.4 0.0 6.1 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 ETS86336.1 - 4.6e-11 41.9 8.1 0.17 12.0 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.22 ETS86336.1 - 5.2e-10 38.9 0.1 1.2e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.6 ETS86336.1 - 5.5e-10 38.7 3.1 0.02 15.1 0.1 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 ETS86336.1 - 2.7e-09 36.5 0.8 0.081 12.8 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS86336.1 - 5.9e-08 33.1 5.6 0.0015 19.0 0.2 5.9 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS86336.1 - 2e-06 27.4 3.5 4.5e-06 26.3 2.4 1.8 1 1 0 1 1 1 1 MalT-like TPR region NACHT PF05729.12 ETS86336.1 - 2.9e-06 27.3 0.0 7.2e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ETS86336.1 - 3e-06 27.6 0.0 8.2e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain TPR_2 PF07719.17 ETS86336.1 - 4.9e-06 26.3 13.2 0.029 14.4 0.1 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 ETS86336.1 - 1.1e-05 25.8 5.6 0.48 11.2 0.1 5.9 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ETS86336.1 - 4e-05 24.1 6.6 0.31 12.0 0.0 7.4 7 2 2 9 9 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 ETS86336.1 - 0.00012 22.2 1.1 5.4 7.6 0.0 4.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 ETS86336.1 - 0.00013 22.0 2.0 0.43 10.7 0.0 4.9 4 2 2 6 6 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 ETS86336.1 - 0.00078 19.8 2.8 1.4 9.8 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat MIT PF04212.18 ETS86336.1 - 0.0021 18.1 1.0 0.19 11.8 0.0 3.4 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain IstB_IS21 PF01695.17 ETS86336.1 - 0.0028 17.4 0.0 0.0071 16.1 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein PPR PF01535.20 ETS86336.1 - 0.0041 17.3 0.0 1.2 9.6 0.0 3.8 4 0 0 4 4 4 1 PPR repeat ANAPC3 PF12895.7 ETS86336.1 - 0.011 15.9 3.6 2.1 8.6 0.6 4.2 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 ETS86336.1 - 0.014 16.0 0.8 1.3 9.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 ETS86336.1 - 0.025 15.2 0.0 0.056 14.0 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sigma54_activat PF00158.26 ETS86336.1 - 0.054 13.2 0.2 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain PGAP1 PF07819.13 ETS86336.1 - 0.099 12.4 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 PGAP1-like protein Ank_2 PF12796.7 ETS86337.1 - 6.5e-24 84.3 12.2 2.4e-09 37.7 0.0 9.6 6 3 4 10 10 10 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS86337.1 - 1.2e-12 46.8 9.9 2.6 8.9 0.0 13.0 14 1 1 15 15 15 3 Ankyrin repeat Ank_4 PF13637.6 ETS86337.1 - 6.9e-11 42.5 0.8 0.0024 18.4 0.0 6.9 6 1 2 8 8 8 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS86337.1 - 0.0003 21.0 6.3 0.18 12.2 0.0 7.1 6 1 2 8 8 8 1 Ankyrin repeats (many copies) Ank PF00023.30 ETS86337.1 - 0.00036 20.8 10.6 10 6.8 0.0 9.1 11 1 0 11 11 11 1 Ankyrin repeat Fungal_trans_2 PF11951.8 ETS86339.1 - 1.2e-06 27.6 2.9 2.8e-06 26.4 0.5 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain HRDC PF00570.23 ETS86339.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 HRDC domain P_C PF06640.11 ETS86339.1 - 0.38 10.9 1.6 1.3 9.2 0.0 2.3 3 0 0 3 3 3 0 P protein C-terminus Pkinase PF00069.25 ETS86340.1 - 0.015 14.7 0.0 0.027 13.8 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.17 ETS86340.1 - 0.14 11.5 0.0 0.29 10.4 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase HET PF06985.11 ETS86341.1 - 1.5e-22 80.5 0.0 2.8e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GLEYA PF10528.9 ETS86342.1 - 4.3e-28 97.6 2.2 4.4e-28 97.6 0.1 2.1 2 1 0 2 2 2 1 GLEYA domain VPS9 PF02204.18 ETS86344.1 - 5.4e-19 68.3 0.0 1.1e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 ETS86344.1 - 3.6e-15 55.8 2.8 2.9e-12 46.6 0.1 4.6 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS86344.1 - 1.7e-12 47.7 0.2 0.00012 22.6 0.0 3.7 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS86344.1 - 1.5e-07 31.8 0.0 0.01 16.4 0.0 5.2 3 1 2 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS86344.1 - 0.00066 19.9 0.1 2.3 9.1 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 ETS86344.1 - 0.028 14.9 3.7 4.1 8.0 0.0 4.2 5 0 0 5 5 5 0 Ankyrin repeat PX PF00787.24 ETS86344.1 - 0.031 14.3 0.1 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 PX domain Methyltransf_11 PF08241.12 ETS86345.1 - 2.3e-22 79.4 0.0 3.7e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS86345.1 - 2.2e-20 73.1 0.0 4.2e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS86345.1 - 2.7e-15 56.6 0.0 3.7e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS86345.1 - 8.5e-15 54.9 0.0 1.7e-14 53.9 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS86345.1 - 1.4e-13 51.4 0.0 2.2e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS86345.1 - 2.2e-07 30.6 0.0 3.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ETS86345.1 - 1.3e-06 28.0 0.0 1.9e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 ETS86345.1 - 1.7e-06 27.2 0.0 2.4e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 ETS86345.1 - 4e-06 26.3 0.0 6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 ETS86345.1 - 1.1e-05 25.0 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 ETS86345.1 - 1.3e-05 24.7 0.0 1.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 ETS86345.1 - 0.00042 19.8 0.0 0.0029 17.1 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase NodS PF05401.11 ETS86345.1 - 0.00045 19.9 0.0 0.00064 19.4 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 ETS86345.1 - 0.0054 16.7 0.0 0.0083 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 ETS86345.1 - 0.0086 16.2 0.0 0.013 15.6 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.12 ETS86345.1 - 0.017 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW HATPase_c PF02518.26 ETS86347.1 - 6e-22 78.3 0.2 1.3e-21 77.2 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ETS86347.1 - 1.1e-21 77.1 0.1 2.4e-21 76.0 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ETS86347.1 - 2.7e-11 43.3 0.0 6.4e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 ETS86347.1 - 6e-07 30.2 0.1 1.3e-06 29.1 0.1 1.6 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 ETS86347.1 - 0.014 15.7 0.1 0.039 14.3 0.0 1.8 2 0 0 2 2 2 0 GAF domain HATPase_c_3 PF13589.6 ETS86347.1 - 0.017 15.0 0.5 0.35 10.7 0.1 2.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Troponin-I_N PF11636.8 ETS86347.1 - 0.13 12.2 2.5 0.44 10.5 2.5 1.9 1 0 0 1 1 1 0 Troponin I residues 1-32 CorA PF01544.18 ETS86348.1 - 3.6e-12 46.2 0.3 7.9e-12 45.1 0.3 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1282 PF06930.12 ETS86348.1 - 0.12 12.1 3.2 0.2 11.4 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) PIG-Y PF15159.6 ETS86348.1 - 5.6 8.0 9.2 12 6.9 9.2 1.6 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y CorA PF01544.18 ETS86349.1 - 2.3e-06 27.2 0.3 2.5e-05 23.8 0.1 2.7 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein LPG_synthase_TM PF03706.13 ETS86349.1 - 0.57 9.7 5.3 0.89 9.0 5.3 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region ORC6 PF05460.13 ETS86349.1 - 8 5.6 12.1 12 5.1 11.0 1.7 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) adh_short PF00106.25 ETS86351.1 - 1.9e-41 141.7 0.0 2.4e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS86351.1 - 6e-33 114.3 0.1 8.1e-33 113.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS86351.1 - 3.4e-10 40.1 0.1 5.7e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ETS86351.1 - 2.3e-06 27.6 0.1 7.5e-06 26.0 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS86351.1 - 0.0049 16.4 0.0 0.015 14.8 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_hydro_43 PF04616.14 ETS86352.1 - 2.5e-65 220.6 0.0 3.4e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ETS86352.1 - 4.1e-11 43.0 0.0 6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Sugar_tr PF00083.24 ETS86353.1 - 1.4e-57 195.5 26.4 1.7e-57 195.3 26.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS86353.1 - 1.7e-12 46.9 39.1 1.7e-12 46.9 39.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Macoilin PF09726.9 ETS86355.1 - 4.5 5.7 17.7 5.9 5.3 17.7 1.1 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 ETS86355.1 - 6.7 5.6 10.5 8.7 5.2 10.5 1.4 1 0 0 1 1 1 0 Mitoguardin SPX PF03105.19 ETS86355.1 - 7.1 6.4 12.7 9.2 6.1 12.7 1.1 1 0 0 1 1 1 0 SPX domain Lin-8 PF03353.15 ETS86355.1 - 8.4 5.9 10.7 16 4.9 10.7 1.5 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist Response_reg PF00072.24 ETS86356.1 - 1.1e-19 70.6 0.1 9.3e-19 67.7 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 ETS86356.1 - 4.1e-18 65.9 0.1 8.1e-18 65.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ETS86356.1 - 1.4e-11 44.3 0.4 3.4e-11 43.0 0.4 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 ETS86356.1 - 0.0054 17.0 0.0 0.016 15.5 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 ETS86356.1 - 0.0064 17.1 0.4 0.079 13.6 0.1 2.9 3 0 0 3 3 3 1 GAF domain DUF4668 PF15701.5 ETS86357.1 - 0.036 13.9 2.7 0.23 11.3 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4668) HemY_N PF07219.13 ETS86357.1 - 0.34 11.1 2.3 0.91 9.7 1.2 2.3 2 0 0 2 2 2 0 HemY protein N-terminus NnrU PF07298.11 ETS86357.1 - 0.99 8.9 8.7 8.1 5.9 6.7 3.1 2 1 1 3 3 3 0 NnrU protein Abhydrolase_9_N PF15420.6 ETS86357.1 - 5.5 6.9 8.9 5.7 6.9 0.9 3.2 3 1 1 4 4 4 0 Alpha/beta-hydrolase family N-terminus Zn_clus PF00172.18 ETS86358.1 - 1.1e-08 35.0 9.8 1.1e-08 35.0 9.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS86358.1 - 0.0017 17.2 0.3 0.0026 16.6 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.28 ETS86359.1 - 1.1e-56 192.8 0.0 1.6e-56 192.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS86359.1 - 4.3e-07 30.0 0.0 0.015 15.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS86359.1 - 0.16 12.5 3.5 0.24 12.0 1.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family p450 PF00067.22 ETS86360.1 - 4.1e-67 226.9 0.0 5.3e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 ETS86361.1 - 2.4e-20 72.7 5.8 3.4e-20 72.2 4.6 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 ETS86361.1 - 4.3e-10 39.5 0.5 1.1e-09 38.2 0.5 1.7 1 0 0 1 1 1 1 Berberine and berberine like Zn_clus PF00172.18 ETS86362.1 - 1e-08 35.1 7.1 1.8e-08 34.3 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS86362.1 - 0.066 12.0 0.2 0.1 11.4 0.2 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Adenylsucc_synt PF00709.21 ETS86363.1 - 1.9e-143 478.4 0.5 8.8e-88 295.0 0.4 2.9 1 1 1 2 2 2 2 Adenylosuccinate synthetase zf-C2H2 PF00096.26 ETS86364.1 - 0.005 17.2 1.2 0.005 17.2 1.2 5.3 5 0 0 5 5 5 1 Zinc finger, C2H2 type bZIP_2 PF07716.15 ETS86364.1 - 0.016 15.3 4.5 0.049 13.7 4.5 1.8 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 ETS86364.1 - 0.71 10.0 12.2 0.029 14.5 6.0 1.9 2 0 0 2 2 2 0 bZIP transcription factor zf-C2H2_4 PF13894.6 ETS86364.1 - 5.5 8.1 29.7 0.59 11.1 1.0 6.3 6 0 0 6 6 6 0 C2H2-type zinc finger zf-RING_2 PF13639.6 ETS86364.1 - 5.6 7.4 6.5 61 4.1 3.9 2.6 2 0 0 2 2 2 0 Ring finger domain Oxysterol_BP PF01237.18 ETS86366.1 - 5.4e-61 206.5 1.5 1.6e-53 181.9 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Asn_synthase PF00733.21 ETS86367.1 - 3.9e-18 66.3 0.6 4.5e-07 29.9 0.0 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 ETS86367.1 - 1.1e-06 28.5 0.0 2e-05 24.5 0.0 2.8 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ETS86367.1 - 0.013 15.7 0.0 0.084 13.1 0.0 2.4 2 0 0 2 2 2 0 Glutamine amidotransferase domain QueC PF06508.13 ETS86367.1 - 0.21 11.1 0.0 0.41 10.1 0.0 1.5 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC AMP-binding PF00501.28 ETS86368.1 - 6.5e-72 242.4 0.0 7.7e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS86368.1 - 3.1e-14 53.7 0.4 7.6e-14 52.4 0.4 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mak16 PF04874.14 ETS86369.1 - 0.59 10.8 15.0 0.97 10.1 15.0 1.4 1 0 0 1 1 1 0 Mak16 protein C-terminal region Paf1 PF03985.13 ETS86369.1 - 1.3 8.0 12.2 1.6 7.6 12.2 1.1 1 0 0 1 1 1 0 Paf1 MFS_1 PF07690.16 ETS86370.1 - 4.4e-47 160.7 48.3 1.1e-45 156.2 45.5 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Tmemb_18A PF09771.9 ETS86370.1 - 0.0076 16.6 0.7 0.061 13.7 1.8 1.9 2 0 0 2 2 2 1 Transmembrane protein 188 DUF969 PF06149.12 ETS86370.1 - 0.033 13.6 2.2 0.04 13.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF969) Sugar_tr PF00083.24 ETS86370.1 - 0.059 12.2 34.5 0.014 14.3 9.8 3.3 2 2 1 3 3 3 0 Sugar (and other) transporter AlaDh_PNT_N PF05222.15 ETS86371.1 - 6.5e-27 94.5 0.0 1e-26 93.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF1996 PF09362.10 ETS86372.1 - 3.4e-76 256.3 3.9 4.3e-76 256.0 3.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RelA_SpoT PF04607.17 ETS86373.1 - 3.3e-18 66.1 1.8 1.2e-17 64.2 0.3 2.3 2 1 0 2 2 2 1 Region found in RelA / SpoT proteins HET PF06985.11 ETS86374.1 - 6.5e-35 120.6 1.7 1.1e-34 119.9 1.7 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M20 PF01546.28 ETS86375.1 - 4.9e-19 68.9 0.1 3.3e-18 66.2 0.1 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ETS86375.1 - 6.9e-18 64.6 0.0 1.2e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ETS86375.1 - 1.1e-06 28.5 0.0 1.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 LysR_substrate PF03466.20 ETS86375.1 - 0.094 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain Epimerase PF01370.21 ETS86376.1 - 1.3e-20 73.9 0.0 1.7e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS86376.1 - 3.4e-13 49.7 0.0 5e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ETS86376.1 - 1.6e-10 40.6 0.0 2.1e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ETS86376.1 - 1.9e-10 40.2 0.0 2.4e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 ETS86376.1 - 9.7e-08 31.7 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 ETS86376.1 - 9.6e-06 24.9 0.5 0.00069 18.9 0.0 2.8 1 1 1 2 2 2 1 Male sterility protein KR PF08659.10 ETS86376.1 - 0.0066 16.4 0.3 0.05 13.5 0.3 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ETS86378.1 - 8.8e-61 205.4 4.6 9.9e-61 205.3 4.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS86378.1 - 2.2e-43 148.0 2.2 2.7e-43 147.7 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS86378.1 - 1.4e-11 44.7 2.0 2.1e-11 44.1 2.0 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 ETS86378.1 - 0.0013 18.7 1.6 0.033 14.2 1.6 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 ETS86378.1 - 0.054 13.4 0.3 0.096 12.6 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 ETS86379.1 - 1.1e-54 185.8 0.8 1.6e-54 185.2 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS86379.1 - 1.2e-08 34.9 6.2 3.1e-08 33.6 6.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.21 ETS86380.1 - 9.7e-112 374.0 44.6 1.2e-111 373.7 44.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS86380.1 - 5.8e-24 84.7 47.9 7e-24 84.4 47.9 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.11 ETS86380.1 - 0.12 11.3 0.1 0.17 10.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) adh_short_C2 PF13561.6 ETS86381.1 - 3.5e-58 196.9 5.7 5.6e-58 196.3 5.7 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS86381.1 - 8.3e-44 149.4 1.3 1.4e-43 148.6 1.3 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS86381.1 - 7.7e-12 45.5 4.6 2.6e-10 40.5 4.6 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS86381.1 - 0.0001 21.8 0.1 0.00015 21.3 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ETS86381.1 - 0.00065 18.9 0.1 0.001 18.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 ETS86381.1 - 0.0074 16.4 0.2 0.028 14.5 0.4 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Adeno_PIX PF03955.14 ETS86381.1 - 0.01 16.0 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 1 Adenovirus hexon-associated protein (IX) 3Beta_HSD PF01073.19 ETS86381.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FMO-like PF00743.19 ETS86382.1 - 5.7e-14 51.4 0.0 2.4e-11 42.8 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ETS86382.1 - 4.1e-10 39.7 0.0 3.1e-07 30.5 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS86382.1 - 2.2e-08 33.7 0.0 3.2e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS86382.1 - 3.9e-08 32.9 0.0 2.1e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS86382.1 - 2.8e-07 30.0 0.0 0.00013 21.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ETS86382.1 - 8.5e-07 29.1 0.0 0.0012 18.8 0.0 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 ETS86382.1 - 4.9e-05 22.7 0.0 0.00071 18.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 ETS86382.1 - 7.1e-05 22.5 0.0 0.0047 16.5 0.0 3.3 2 1 0 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 ETS86382.1 - 0.00036 19.9 0.0 0.00063 19.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ETS86382.1 - 0.00084 19.4 0.0 0.016 15.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 ETS86382.1 - 0.01 16.3 0.0 0.082 13.4 0.0 2.5 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ETS86382.1 - 0.082 13.2 0.0 10 6.4 0.0 2.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Ank_2 PF12796.7 ETS86383.1 - 3.4e-34 117.3 0.0 6.4e-11 42.7 0.0 6.6 4 2 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS86383.1 - 4.5e-18 63.5 0.0 0.0054 17.1 0.0 8.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 ETS86383.1 - 3.7e-17 62.2 2.6 1.5e-05 25.2 0.0 6.5 3 1 4 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 ETS86383.1 - 8.1e-16 57.7 0.4 0.015 15.7 0.0 8.1 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 ETS86383.1 - 3.4e-15 56.2 0.0 2.1e-07 31.3 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeats (many copies) GUCT PF08152.12 ETS86383.1 - 0.077 13.3 1.1 2.1 8.7 0.1 3.6 2 1 3 5 5 5 0 GUCT (NUC152) domain NAD_Gly3P_dh_C PF07479.14 ETS86383.1 - 4.1 7.7 5.0 50 4.2 0.0 3.7 1 1 2 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NigD_C PF17415.2 ETS86384.1 - 0.057 13.5 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 NigD-like C-terminal beta sandwich domain DUF3916 PF13079.6 ETS86385.1 - 0.059 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3916) Vps35 PF03635.17 ETS86386.1 - 0 1028.7 0.0 0 1028.5 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Borrelia_P83 PF05262.11 ETS86387.1 - 0.0023 16.5 28.6 0.0025 16.4 28.6 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein Presenilin PF01080.17 ETS86387.1 - 0.006 15.4 23.9 0.0081 15.0 23.9 1.2 1 0 0 1 1 1 1 Presenilin CDC27 PF09507.10 ETS86387.1 - 0.073 12.4 41.7 0.1 12.0 41.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Zip PF02535.22 ETS86387.1 - 0.094 11.9 15.9 0.13 11.5 15.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2151 PF10221.9 ETS86387.1 - 0.15 10.6 20.9 0.18 10.4 20.9 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Nop14 PF04147.12 ETS86387.1 - 0.27 9.4 42.2 0.4 8.8 42.2 1.2 1 0 0 1 1 1 0 Nop14-like family Apt1 PF10351.9 ETS86387.1 - 0.53 9.1 18.1 0.66 8.8 18.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4045 PF13254.6 ETS86387.1 - 0.9 9.1 32.1 1.2 8.7 32.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Asp-B-Hydro_N PF05279.11 ETS86387.1 - 0.91 9.5 41.8 1.4 8.9 41.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SOBP PF15279.6 ETS86387.1 - 0.91 10.1 14.7 1.2 9.7 14.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein RR_TM4-6 PF06459.12 ETS86387.1 - 1 9.1 41.6 2.1 8.1 41.6 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 ETS86387.1 - 1.2 8.4 48.4 2.1 7.7 48.4 1.3 1 0 0 1 1 1 0 SDA1 LAP1C PF05609.12 ETS86387.1 - 1.4 7.9 21.9 1.9 7.5 21.9 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4551 PF15087.6 ETS86387.1 - 1.6 7.5 18.1 1.9 7.2 18.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4778 PF16008.5 ETS86387.1 - 2.1 8.4 20.2 2.7 8.0 20.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) CDC45 PF02724.14 ETS86387.1 - 4.2 5.6 44.2 5.8 5.1 44.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF966 PF06136.13 ETS86387.1 - 4.6 6.8 24.6 6.5 6.4 24.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) GREB1 PF15782.5 ETS86387.1 - 4.9 4.2 13.7 5.9 3.9 13.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer eIF3_subunit PF08597.10 ETS86387.1 - 5.9 6.7 57.4 3.5 7.5 54.2 2.0 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF3807 PF12720.7 ETS86387.1 - 6.7 6.9 39.1 16 5.7 39.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) TFR_dimer PF04253.15 ETS86388.1 - 3.8e-30 104.5 0.0 6.5e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 ETS86388.1 - 3.2e-24 85.7 0.0 5.6e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ETS86388.1 - 1.5e-12 47.4 0.0 6.6e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 ETS86388.1 - 0.017 14.9 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 PhoLip_ATPase_C PF16212.5 ETS86390.1 - 1.1e-66 225.1 15.1 1.1e-66 225.1 15.1 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ETS86390.1 - 1.1e-24 85.8 0.8 7.7e-23 80.0 0.2 2.9 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 ETS86390.1 - 1.9e-12 47.1 0.0 5.2e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 ETS86390.1 - 1.4e-11 44.3 0.0 2.2e-10 40.5 0.0 2.5 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ETS86390.1 - 5.1e-11 43.3 0.1 7e-05 23.2 0.0 3.5 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ETS86390.1 - 0.0055 16.5 0.0 0.014 15.1 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase VPS9 PF02204.18 ETS86391.1 - 3.9e-30 104.1 0.1 6.7e-30 103.4 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 ETS86391.1 - 6.5e-17 61.6 0.4 1.6e-16 60.3 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 ETS86391.1 - 1.2e-08 34.5 0.0 3.5e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 CUE domain TauD PF02668.16 ETS86393.1 - 3.1e-51 174.8 0.0 3.6e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 ETS86394.1 - 6.4e-26 91.1 33.4 1.5e-25 89.9 33.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily HET PF06985.11 ETS86395.1 - 3.2e-12 47.0 9.2 2e-10 41.2 1.8 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 ETS86396.1 - 3.2e-35 121.7 56.5 3.2e-35 121.7 56.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS86396.1 - 5e-11 42.1 11.4 5e-11 42.1 11.4 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter PAS_9 PF13426.7 ETS86397.1 - 4.3e-15 55.9 0.0 2.5e-14 53.4 0.0 2.4 2 0 0 2 2 2 1 PAS domain RGS PF00615.19 ETS86397.1 - 1.2e-14 54.6 0.4 1.2e-14 54.6 0.4 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain PAS PF00989.25 ETS86397.1 - 5e-05 23.3 0.0 0.00034 20.6 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 ETS86397.1 - 0.00016 21.9 0.0 0.032 14.5 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 ETS86397.1 - 0.00054 20.2 0.0 0.0022 18.2 0.0 2.1 1 0 0 1 1 1 1 PAS fold Abhydrolase_4 PF08386.10 ETS86398.1 - 1e-19 70.5 0.1 3e-19 69.0 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 ETS86398.1 - 1.7e-19 70.5 0.0 2e-14 53.8 0.0 2.6 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS86398.1 - 0.069 12.4 0.0 0.61 9.3 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 NAD_binding_8 PF13450.6 ETS86399.1 - 5.8e-13 48.9 0.2 1.6e-12 47.5 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS86399.1 - 1.3e-09 38.2 0.1 1.1e-07 31.8 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS86399.1 - 1.8e-06 27.4 0.0 0.00011 21.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS86399.1 - 0.00016 20.9 0.0 0.00025 20.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ETS86399.1 - 0.00044 20.8 0.0 1.8 9.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ETS86399.1 - 0.00065 19.1 1.0 0.015 14.7 0.0 2.8 3 1 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 ETS86399.1 - 0.001 19.1 0.0 0.0033 17.4 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 ETS86399.1 - 0.0034 16.6 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 ETS86399.1 - 0.0036 16.1 0.0 0.017 13.8 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 ETS86399.1 - 0.025 13.6 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 ETS86399.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Aldo_ket_red PF00248.21 ETS86401.1 - 1.1e-57 195.6 0.0 1.2e-57 195.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Dus PF01207.17 ETS86402.1 - 2e-33 115.8 0.0 1.9e-29 102.7 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) Cyclin_N PF00134.23 ETS86403.1 - 7.1e-13 48.4 0.1 1.6e-12 47.3 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ndc1_Nup PF09531.10 ETS86403.1 - 0.85 8.2 9.8 0.71 8.5 0.2 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.32 ETS86404.1 - 4.5e-39 131.7 14.7 1.2e-07 32.3 0.0 7.5 7 1 0 7 7 7 5 WD domain, G-beta repeat PRP4 PF08799.11 ETS86404.1 - 4.2e-16 58.2 2.3 9.3e-16 57.1 2.3 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 ETS86404.1 - 4.3e-14 52.6 0.5 0.024 14.9 0.1 5.7 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS86404.1 - 0.015 14.2 0.0 5.6 5.8 0.0 3.4 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ETS86404.1 - 0.12 12.2 0.0 2.3 8.1 0.0 2.5 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ETS86404.1 - 0.31 10.3 0.0 14 4.9 0.0 2.7 2 1 0 2 2 2 0 WD40-like domain Melibiase_2 PF16499.5 ETS86405.1 - 1.1e-45 156.1 0.3 2.3e-45 155.0 0.3 1.6 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 ETS86405.1 - 1.7e-10 40.8 0.2 4.1e-10 39.6 0.2 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain PBP PF01161.20 ETS86407.1 - 5.2e-11 43.0 0.3 6.3e-11 42.7 0.3 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SNF2_N PF00176.23 ETS86408.1 - 1.4e-36 125.9 0.0 4.8e-32 111.0 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS86408.1 - 2.4e-06 27.9 0.1 5.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ETS86408.1 - 0.0031 17.3 0.0 0.0082 15.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ETS86408.1 - 0.0096 15.9 0.0 3.7 7.5 0.0 3.2 4 0 0 4 4 4 2 Type III restriction enzyme, res subunit Aldedh PF00171.22 ETS86409.1 - 2e-106 356.3 0.0 2.6e-106 355.9 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PhoD PF09423.10 ETS86410.1 - 8.7e-05 21.7 0.7 0.0023 17.0 0.1 2.7 3 0 0 3 3 3 2 PhoD-like phosphatase Rhomboid PF01694.22 ETS86411.1 - 1.3e-22 80.4 14.2 2.2e-22 79.7 14.2 1.3 1 0 0 1 1 1 1 Rhomboid family Peptidase_M20 PF01546.28 ETS86412.1 - 3.2e-29 102.1 0.0 7.6e-29 100.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ETS86412.1 - 1.1e-09 38.2 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ETS86412.1 - 0.1 12.3 0.0 0.38 10.4 0.0 1.9 1 1 0 1 1 1 0 Peptidase family M28 Ank_2 PF12796.7 ETS86413.1 - 8.2e-81 266.7 17.0 5.4e-13 49.3 0.0 8.0 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS86413.1 - 3.5e-71 234.7 12.9 7e-09 36.1 0.0 12.5 4 2 9 13 13 13 12 Ankyrin repeats (many copies) Ank PF00023.30 ETS86413.1 - 2.3e-59 195.4 28.7 1.1e-05 25.6 0.0 13.5 13 0 0 13 13 13 13 Ankyrin repeat Ank_3 PF13606.6 ETS86413.1 - 7.7e-50 161.1 13.2 7.1e-05 22.9 0.0 14.6 15 0 0 15 15 13 8 Ankyrin repeat Ank_5 PF13857.6 ETS86413.1 - 7.2e-48 160.0 14.5 9.3e-10 38.6 0.0 9.4 6 4 2 9 9 8 8 Ankyrin repeats (many copies) NACHT PF05729.12 ETS86413.1 - 1.9e-06 27.9 0.1 4.3e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS86413.1 - 4.2e-06 27.2 0.1 0.00011 22.6 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS86413.1 - 0.00025 21.4 0.0 0.0036 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF4988 PF16378.5 ETS86413.1 - 0.00031 20.5 0.1 4.9 6.8 0.0 4.9 2 1 2 5 5 5 1 Domain of unknown function ABC_tran PF00005.27 ETS86413.1 - 0.00083 19.9 0.0 0.023 15.2 0.0 2.8 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.22 ETS86413.1 - 0.0072 16.7 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 ETS86413.1 - 0.0094 16.5 0.0 0.031 14.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 ETS86413.1 - 0.011 15.5 0.0 0.074 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Nitro_FeMo-Co PF02579.17 ETS86413.1 - 0.023 15.0 1.9 89 3.5 0.0 5.6 3 2 3 8 8 7 0 Dinitrogenase iron-molybdenum cofactor KAP_NTPase PF07693.14 ETS86413.1 - 0.025 13.8 0.7 0.81 8.9 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain RsgA_GTPase PF03193.16 ETS86413.1 - 0.045 13.7 0.0 0.86 9.5 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 ETS86413.1 - 0.12 12.5 0.0 0.59 10.2 0.0 2.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 ETS86415.1 - 7e-15 55.3 0.1 1.4e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ETS86415.1 - 0.0017 18.6 0.0 0.0036 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 ETS86415.1 - 0.0053 16.7 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 AAA_16 PF13191.6 ETS86415.1 - 0.01 16.2 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 ETS86415.1 - 0.014 15.8 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase VWD PF00094.25 ETS86415.1 - 0.026 14.8 0.1 0.075 13.3 0.0 1.8 2 0 0 2 2 2 0 von Willebrand factor type D domain AAA_19 PF13245.6 ETS86415.1 - 0.14 12.5 0.0 0.29 11.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain SesA PF17107.5 ETS86416.1 - 1.6e-12 47.7 0.3 3.3e-12 46.7 0.1 1.6 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases SSXT PF05030.12 ETS86416.1 - 0.033 13.8 0.1 0.068 12.8 0.1 1.5 1 0 0 1 1 1 0 SSXT protein (N-terminal region) DUF4862 PF16154.5 ETS86416.1 - 0.076 12.4 0.1 0.17 11.2 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4862) SesA PF17107.5 ETS86417.1 - 4.4e-06 26.9 0.1 4.9e-06 26.7 0.1 1.1 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases F-box PF00646.33 ETS86418.1 - 0.016 15.1 0.1 0.045 13.7 0.1 1.8 1 0 0 1 1 1 0 F-box domain SLY PF12485.8 ETS86421.1 - 0.02 15.6 0.2 0.022 15.5 0.2 1.1 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein FAD_binding_2 PF00890.24 ETS86422.1 - 4.7e-125 417.9 2.9 5.7e-125 417.7 2.9 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 ETS86422.1 - 1.9e-44 150.8 0.2 2.8e-44 150.2 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 ETS86422.1 - 5e-06 26.0 0.1 0.0019 17.5 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS86422.1 - 3.9e-05 22.9 1.3 0.017 14.3 2.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 ETS86422.1 - 6.5e-05 22.3 0.2 0.03 13.6 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 ETS86422.1 - 0.0026 17.1 0.5 0.0057 15.9 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 ETS86422.1 - 0.046 13.3 0.2 0.11 12.0 0.2 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS86422.1 - 0.084 11.6 0.7 0.28 9.8 0.3 2.0 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 ETS86422.1 - 0.17 10.9 0.1 0.43 9.6 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein DUF3818 PF12825.7 ETS86423.1 - 1.5e-129 431.8 7.3 2.7e-129 431.0 7.3 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 ETS86423.1 - 1.9e-39 134.6 0.8 4.1e-39 133.5 0.8 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.24 ETS86423.1 - 2.9e-16 59.5 0.9 9.7e-15 54.5 0.0 3.6 3 1 0 3 3 3 1 PX domain DUF3381 PF11861.8 ETS86423.1 - 0.01 15.7 3.1 0.038 13.8 3.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Cwf_Cwc_15 PF04889.12 ETS86423.1 - 0.094 12.4 5.1 0.26 11.0 5.1 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RE_Bpu10I PF09549.10 ETS86423.1 - 0.16 11.5 4.2 0.049 13.2 1.0 1.7 2 0 0 2 2 2 0 Bpu10I restriction endonuclease Spc7 PF08317.11 ETS86424.1 - 0.014 14.3 3.1 0.023 13.6 3.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HrpB7 PF09486.10 ETS86424.1 - 0.015 15.7 8.3 0.5 10.7 7.2 2.8 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4618 PF15397.6 ETS86424.1 - 0.032 13.6 1.7 0.058 12.8 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Fib_alpha PF08702.10 ETS86424.1 - 0.035 14.3 1.0 0.078 13.2 1.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.6 ETS86424.1 - 0.056 13.9 1.2 0.15 12.5 0.8 1.9 1 1 0 1 1 1 0 Snapin/Pallidin DivIC PF04977.15 ETS86424.1 - 0.059 13.1 1.9 0.17 11.7 1.9 1.8 1 0 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 ETS86424.1 - 0.082 13.4 5.6 0.29 11.6 3.6 2.4 1 1 1 2 2 2 0 Cell division protein ZapB DUF1664 PF07889.12 ETS86424.1 - 0.092 12.8 3.5 2 8.4 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3357 PF11837.8 ETS86424.1 - 0.1 13.1 0.1 0.32 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DotU PF09850.9 ETS86424.1 - 0.13 12.0 2.3 0.24 11.1 1.5 1.9 1 1 1 2 2 2 0 Type VI secretion system protein DotU DUF485 PF04341.12 ETS86424.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 SlyX PF04102.12 ETS86424.1 - 0.14 12.8 2.4 0.62 10.7 2.4 2.2 1 0 0 1 1 1 0 SlyX Atg14 PF10186.9 ETS86424.1 - 0.37 9.8 4.5 0.64 9.0 4.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4164 PF13747.6 ETS86424.1 - 0.54 10.6 5.2 0.49 10.7 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) MCU PF04678.13 ETS86424.1 - 0.55 10.3 2.7 0.82 9.8 1.3 1.9 1 1 0 2 2 2 0 Mitochondrial calcium uniporter GP41 PF00517.17 ETS86424.1 - 4.9 7.0 6.1 3.7 7.4 3.1 2.2 1 1 2 3 3 3 0 Retroviral envelope protein Cgr1 PF03879.14 ETS86425.1 - 1.4e-34 118.7 32.6 1.6e-34 118.5 32.6 1.0 1 0 0 1 1 1 1 Cgr1 family VIR_N PF15912.5 ETS86425.1 - 1.4 8.5 7.4 1.7 8.2 7.4 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal CDC27 PF09507.10 ETS86425.1 - 2.1 7.6 21.3 2.6 7.3 21.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.12 ETS86425.1 - 4.1 7.2 16.1 4.3 7.1 16.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 F-box-like PF12937.7 ETS86427.1 - 7.2e-06 25.8 0.1 2.8e-05 23.9 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS86427.1 - 0.0014 18.4 0.0 0.0071 16.2 0.0 2.3 1 1 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ETS86427.1 - 0.018 14.9 0.4 0.34 10.8 0.0 2.9 3 1 1 4 4 4 0 F-box Neur_chan_memb PF02932.16 ETS86428.1 - 0.01 15.9 0.6 3 7.9 0.8 2.1 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4203 PF13886.6 ETS86428.1 - 0.061 13.0 5.5 0.086 12.5 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) P34-Arc PF04045.14 ETS86428.1 - 0.099 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Arp2/3 complex, 34 kD subunit p34-Arc GREB1 PF15782.5 ETS86431.1 - 1.3 6.1 10.2 1.3 6.0 10.2 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4611 PF15387.6 ETS86431.1 - 3.1 8.1 16.1 0.91 9.8 2.5 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) Dicty_REP PF05086.12 ETS86431.1 - 3.8 5.4 11.0 5.5 4.8 11.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TRP PF06011.12 ETS86432.1 - 1.7e-35 122.6 26.0 4e-34 118.1 26.0 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 ETS86432.1 - 5.7e-20 72.1 0.0 8.8e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Amidohydro_2 PF04909.14 ETS86433.1 - 3e-47 161.8 0.1 3.5e-47 161.6 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase AIRC PF00731.20 ETS86434.1 - 1.6e-61 206.2 0.9 5.9e-61 204.4 0.5 2.2 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 ETS86434.1 - 7.3e-50 168.9 0.0 1.5e-49 167.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 ETS86434.1 - 2.3e-13 49.6 0.1 6e-13 48.3 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 ETS86434.1 - 9.4e-07 28.6 0.0 2.1e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus PrpR_N PF06506.11 ETS86434.1 - 0.015 14.9 0.5 0.31 10.6 0.0 2.9 3 0 0 3 3 3 0 Propionate catabolism activator XdhC_C PF13478.6 ETS86434.1 - 0.033 14.7 0.1 2.9 8.4 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 ETS86434.1 - 0.094 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ATP-grasp_4 PF13535.6 ETS86434.1 - 0.12 11.9 0.0 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain IFT57 PF10498.9 ETS86435.1 - 5.1 6.0 5.1 11 4.9 5.1 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 HATPase_c_3 PF13589.6 ETS86436.1 - 1.2e-09 38.1 0.0 2.3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ETS86436.1 - 3.5e-07 30.7 0.0 7.8e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 ETS86436.1 - 5.3e-07 29.3 0.0 1.6e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain DMRL_synthase PF00885.19 ETS86437.1 - 1.3e-56 190.3 0.1 1.6e-56 190.0 0.1 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase PBP1_TM PF14812.6 ETS86438.1 - 5.1 7.5 18.3 9.3 6.7 10.6 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cation_efflux PF01545.21 ETS86439.1 - 1.5e-26 93.4 10.0 2e-26 93.0 10.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ETS86439.1 - 4.7e-06 26.6 0.0 9.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF4271 PF14093.6 ETS86439.1 - 1.3 8.9 6.0 0.22 11.4 1.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) zf-CCCH PF00642.24 ETS86441.1 - 8.2e-09 35.2 18.5 3e-07 30.2 2.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 ETS86441.1 - 0.00085 19.1 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 ETS86441.1 - 0.0058 16.6 3.3 0.0058 16.6 3.3 3.3 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 ETS86441.1 - 0.011 16.4 2.9 0.52 11.0 0.2 2.4 2 0 0 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 ETS86441.1 - 0.11 12.7 3.6 0.22 11.7 0.2 2.4 2 1 0 2 2 2 0 Zinc-finger containing family Oxysterol_BP PF01237.18 ETS86442.1 - 9e-91 304.5 0.0 3.6e-88 295.9 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein SET PF00856.28 ETS86443.1 - 6.8e-15 55.9 0.0 3.2e-14 53.7 0.0 2.0 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 ETS86443.1 - 4.4e-07 29.9 15.6 4.4e-07 29.9 15.6 2.5 2 1 0 2 2 2 1 MYND finger peroxidase PF00141.23 ETS86444.1 - 2e-20 73.5 0.1 3.4e-20 72.7 0.1 1.3 1 0 0 1 1 1 1 Peroxidase adh_short PF00106.25 ETS86445.1 - 8.4e-36 123.3 0.0 1.1e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS86445.1 - 6.1e-22 78.3 0.0 8.1e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS86445.1 - 6.2e-08 32.8 0.1 1.6e-07 31.4 0.1 1.7 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 ETS86445.1 - 8.4e-06 25.4 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 ETS86445.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 ETS86445.1 - 0.094 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase B12-binding PF02310.19 ETS86445.1 - 0.097 12.7 0.0 0.3 11.1 0.0 1.8 1 1 0 1 1 1 0 B12 binding domain Epimerase PF01370.21 ETS86445.1 - 0.13 11.7 0.2 0.25 10.8 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DnaT PF17948.1 ETS86447.1 - 0.028 14.1 0.1 0.2 11.4 0.0 2.3 3 0 0 3 3 3 0 DnaT DNA-binding domain Y_Y_Y PF07495.13 ETS86447.1 - 0.052 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Y_Y_Y domain EphA2_TM PF14575.6 ETS86448.1 - 0.026 15.4 0.0 0.045 14.6 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 ETS86448.1 - 0.037 13.9 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 TMEM154 protein family Gly-zipper_Omp PF13488.6 ETS86448.1 - 0.06 13.3 0.5 0.13 12.3 0.5 1.5 1 0 0 1 1 1 0 Glycine zipper Amnionless PF14828.6 ETS86448.1 - 0.082 11.7 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Amnionless zf-C2H2_10 PF16588.5 ETS86448.1 - 0.21 11.3 2.4 0.38 10.5 2.4 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger PRIMA1 PF16101.5 ETS86448.1 - 0.47 10.5 0.0 0.47 10.5 0.0 3.6 2 1 1 3 3 3 0 Proline-rich membrane anchor 1 Glyco_hydro_53 PF07745.13 ETS86449.1 - 2e-106 355.8 1.2 2.3e-106 355.6 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Ank_2 PF12796.7 ETS86452.1 - 1.3e-14 54.5 0.0 1e-07 32.4 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 ETS86452.1 - 8.4e-14 51.3 1.9 5.2e-05 23.5 0.0 4.7 4 1 1 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 ETS86452.1 - 1e-10 41.9 0.2 0.0001 22.8 0.0 4.1 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS86452.1 - 5.6e-10 38.6 0.5 0.0032 17.8 0.0 5.3 5 1 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 ETS86452.1 - 3.5e-07 30.4 0.1 0.033 14.5 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) HET PF06985.11 ETS86453.1 - 5.1e-25 88.5 0.0 1.1e-24 87.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ETS86455.1 - 1.1e-20 74.5 0.0 2.6e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GSH-S_ATP PF02955.16 ETS86455.1 - 0.1 12.0 0.0 0.61 9.5 0.1 2.0 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain HET PF06985.11 ETS86456.1 - 8.4e-24 84.6 0.0 1.5e-23 83.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CMD PF02627.20 ETS86456.1 - 0.065 13.3 0.0 0.24 11.5 0.0 2.0 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Methyltransf_12 PF08242.12 ETS86457.1 - 0.00082 20.1 0.1 0.0026 18.5 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS86457.1 - 0.029 15.1 0.0 0.1 13.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 ETS86457.1 - 0.082 12.7 0.0 0.16 11.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain LcnG-beta PF11632.8 ETS86457.1 - 0.083 12.9 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Lactococcin G-beta Methyltransf_11 PF08241.12 ETS86457.1 - 0.092 13.4 0.0 0.29 11.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Peptidase_C12 PF01088.21 ETS86458.1 - 5.5e-18 65.5 0.0 6.3e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Peptidase_C12 PF01088.21 ETS86459.1 - 7.1e-28 97.8 0.0 8.4e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyco_hydro_106 PF17132.4 ETS86460.1 - 3.5e-12 45.5 0.1 1.5e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 alpha-L-rhamnosidase Glyco_hydro_2_N PF02837.18 ETS86460.1 - 0.011 15.7 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Ank_2 PF12796.7 ETS86461.1 - 2.3e-36 124.2 6.4 8.9e-07 29.4 0.1 8.9 5 2 3 9 9 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS86461.1 - 1e-26 92.9 8.9 0.00016 22.2 0.0 10.2 10 0 0 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS86461.1 - 3.7e-24 82.2 10.5 0.062 13.9 0.0 13.4 14 1 1 15 15 15 7 Ankyrin repeat Ank PF00023.30 ETS86461.1 - 4.6e-12 45.8 16.3 2.6 8.7 0.2 12.4 13 1 0 13 13 13 5 Ankyrin repeat Ank_5 PF13857.6 ETS86461.1 - 2.9e-09 37.0 3.0 4.3 7.8 0.0 7.8 7 2 3 10 10 10 4 Ankyrin repeats (many copies) Lipase_GDSL_2 PF13472.6 ETS86463.1 - 3.2e-27 96.1 7.2 1.8e-19 70.8 3.1 3.0 3 1 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS86463.1 - 2.2e-12 47.4 3.0 4.4e-10 39.9 0.2 2.9 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 ETS86463.1 - 0.00052 20.2 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ketoacyl-synt PF00109.26 ETS86466.1 - 2.1e-72 243.8 0.0 5.8e-72 242.3 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 ETS86466.1 - 1.8e-48 165.3 0.0 3.3e-48 164.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ETS86466.1 - 4.7e-48 164.3 0.0 8.3e-48 163.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 ETS86466.1 - 4.3e-46 157.1 0.0 1.1e-45 155.8 0.0 1.7 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 ETS86466.1 - 1.9e-32 111.8 0.3 8.6e-32 109.6 0.1 2.3 3 0 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ETS86466.1 - 1.4e-19 70.7 0.0 4.1e-19 69.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ETS86466.1 - 4.1e-14 53.0 0.0 1.2e-13 51.5 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 ETS86466.1 - 7.1e-13 48.7 0.0 1.5e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS86466.1 - 1e-11 45.4 0.0 3.5e-11 43.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS86466.1 - 6.6e-11 42.7 0.0 1.6e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS86466.1 - 6.2e-10 39.1 0.0 1.8e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 ETS86466.1 - 7e-09 35.4 0.0 2.3e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 ETS86466.1 - 7.1e-08 32.7 0.1 1.8e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 ETS86466.1 - 5e-06 26.0 0.0 9.3e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 ETS86466.1 - 5.3e-06 26.0 0.1 1.2e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 ETS86466.1 - 0.00076 19.3 0.0 0.0025 17.6 0.0 1.8 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_2 PF00891.18 ETS86466.1 - 0.012 14.9 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Exotox-A_target PF09102.10 ETS86466.1 - 0.019 15.0 0.5 0.88 9.6 0.0 2.5 2 0 0 2 2 2 0 Exotoxin A, targeting NodS PF05401.11 ETS86466.1 - 0.067 12.8 0.0 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 Nodulation protein S (NodS) FAD_binding_3 PF01494.19 ETS86467.1 - 4.7e-27 95.1 0.0 8.3e-27 94.3 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 ETS86467.1 - 6.1e-07 29.1 0.2 0.00074 18.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 ETS86467.1 - 2.5e-06 26.8 0.7 0.0095 15.0 0.3 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.22 ETS86467.1 - 2.7e-05 23.4 0.1 5.8e-05 22.3 0.1 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ETS86467.1 - 0.00012 22.2 0.4 0.00038 20.6 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS86467.1 - 0.00013 21.4 0.5 0.0056 16.0 0.5 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS86467.1 - 0.00019 20.8 0.8 0.0015 17.8 0.7 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS86467.1 - 0.00031 20.4 1.6 0.0012 18.5 1.3 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ETS86467.1 - 0.0017 17.1 0.3 0.26 9.9 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 ETS86467.1 - 0.0025 17.0 1.2 0.004 16.3 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain Rossmann-like PF10727.9 ETS86467.1 - 0.031 14.1 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain Pyr_redox PF00070.27 ETS86467.1 - 0.058 14.0 0.2 0.058 14.0 0.2 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase TyeA PF09059.10 ETS86467.1 - 0.11 12.6 0.1 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 TyeA Trp_halogenase PF04820.14 ETS86467.1 - 0.12 11.2 1.2 0.2 10.5 0.4 1.7 1 1 1 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 ETS86467.1 - 0.19 10.9 0.3 0.35 10.1 0.3 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 ETS86467.1 - 0.3 11.1 1.4 26 4.8 0.3 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding ADH_zinc_N PF00107.26 ETS86468.1 - 1e-14 54.6 0.0 2.3e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS86468.1 - 3.5e-06 28.1 0.0 8.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS86468.1 - 0.00035 20.4 0.2 0.0007 19.5 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.22 ETS86469.1 - 2e-22 79.6 0.0 1.6e-21 76.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 FSH1 PF03959.13 ETS86470.1 - 1.4e-28 100.1 0.0 1.7e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 ETS86470.1 - 0.00016 22.4 0.0 0.00019 22.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 ETS86470.1 - 0.0072 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF900 PF05990.12 ETS86470.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PE-PPE PF08237.11 ETS86470.1 - 0.19 11.3 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Aldose_epim PF01263.20 ETS86471.1 - 1.8e-26 93.2 0.0 2.2e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase MFS_1 PF07690.16 ETS86472.1 - 6.7e-28 97.6 58.6 3.6e-18 65.6 18.4 4.7 3 2 2 5 5 5 3 Major Facilitator Superfamily TRI12 PF06609.13 ETS86472.1 - 1.4e-08 33.6 12.9 2.4e-08 32.9 12.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 ETS86472.1 - 0.0052 15.1 2.1 0.0052 15.1 2.1 2.3 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 ETS86473.1 - 0.024 13.7 0.5 0.099 11.7 0.1 2.0 2 0 0 2 2 2 0 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 ETS86475.1 - 0.021 13.7 0.0 0.043 12.6 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain adh_short PF00106.25 ETS86476.1 - 9e-35 119.9 0.0 1.2e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS86476.1 - 1.8e-26 93.1 0.0 2.7e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 ETS86476.1 - 5.3e-07 29.4 0.2 1e-06 28.5 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS86476.1 - 1.7e-06 28.0 0.2 3e-06 27.3 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 ETS86476.1 - 0.002 17.6 0.0 0.73 9.1 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 ETS86476.1 - 0.015 15.1 0.1 0.024 14.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Endonuc-PvuII PF09225.10 ETS86477.1 - 0.088 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease PvuII Tyrosinase PF00264.20 ETS86478.1 - 4.3e-40 138.4 0.5 5.6e-40 138.0 0.5 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase HMG_box PF00505.19 ETS86478.1 - 0.13 12.7 0.1 0.2 12.1 0.1 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box FAD_binding_3 PF01494.19 ETS86479.1 - 9.1e-16 58.0 0.3 7.1e-06 25.5 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 ETS86479.1 - 1.1e-08 34.7 1.1 0.0029 16.9 0.3 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS86479.1 - 4.5e-06 26.8 0.2 3e-05 24.1 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS86479.1 - 3.8e-05 23.0 0.1 6.6e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ETS86479.1 - 9.4e-05 21.3 0.1 0.0056 15.4 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 ETS86479.1 - 0.00019 21.1 0.6 0.0093 15.6 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS86479.1 - 0.0004 20.9 0.5 0.2 12.3 0.4 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS86479.1 - 0.00049 19.3 0.2 0.00093 18.4 0.2 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 ETS86479.1 - 0.0046 16.1 0.2 0.034 13.2 0.2 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 ETS86479.1 - 0.008 15.6 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ETS86479.1 - 0.014 14.7 0.3 0.023 14.0 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ETS86479.1 - 0.045 13.0 0.0 0.078 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 ETS86479.1 - 0.063 12.5 0.2 0.37 10.0 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS86479.1 - 0.33 10.9 1.0 22 5.0 0.1 3.1 3 1 1 4 4 4 0 FAD-NAD(P)-binding p450 PF00067.22 ETS86480.1 - 2.8e-82 276.9 0.0 3.3e-82 276.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3328 PF11807.8 ETS86481.1 - 3.9e-21 75.8 2.6 6.8e-21 75.1 2.6 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) OB_aCoA_assoc PF01796.17 ETS86482.1 - 1.2 9.1 3.1 2.7 8.1 0.2 3.0 2 1 2 4 4 4 0 DUF35 OB-fold domain, acyl-CoA-associated GSDH PF07995.11 ETS86483.1 - 4.9e-06 26.1 0.0 1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Pkinase PF00069.25 ETS86484.1 - 7.4e-08 32.1 0.0 2e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS86484.1 - 4.9e-05 22.7 0.0 8.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ofd1_CTDD PF10637.9 ETS86484.1 - 0.043 13.1 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term MSV199 PF10553.9 ETS86484.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 MSV199 domain Pre-PUA PF17832.1 ETS86485.1 - 1.2e-22 80.3 0.2 1.7e-22 79.9 0.2 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 ETS86485.1 - 6.8e-11 42.0 0.1 4.4e-10 39.4 0.1 2.0 1 1 0 1 1 1 1 PUA domain DUF1947 PF09183.10 ETS86485.1 - 0.069 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) Inhibitor_I78 PF11720.8 ETS86486.1 - 3.3e-10 39.9 0.0 4.2e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 ETS86486.1 - 0.0084 16.8 0.0 0.012 16.2 0.0 1.3 1 0 0 1 1 1 1 Potato inhibitor I family SBE2 PF17076.5 ETS86487.1 - 0.43 8.7 8.8 0.5 8.5 8.8 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation SWI-SNF_Ssr4 PF08549.10 ETS86487.1 - 1 7.9 7.6 1.1 7.8 7.6 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) MCM_bind PF09739.9 ETS86487.1 - 2.1 6.7 5.4 3.1 6.1 5.4 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NST1 PF13945.6 ETS86489.1 - 2.6e-51 174.4 9.8 2.6e-51 174.4 9.8 2.6 1 1 2 3 3 3 1 Salt tolerance down-regulator Lentiviral_Tat PF02998.14 ETS86489.1 - 0.24 11.5 0.8 0.55 10.3 0.8 1.6 1 0 0 1 1 1 0 Lentiviral Tat protein TMA7 PF09072.10 ETS86489.1 - 0.32 11.9 0.2 0.32 11.9 0.2 4.7 5 0 0 5 5 5 0 Translation machinery associated TMA7 Ras PF00071.22 ETS86490.1 - 3.5e-50 169.8 0.0 4e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS86490.1 - 4.5e-22 78.5 0.0 6.6e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS86490.1 - 8.1e-07 28.7 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ETS86490.1 - 0.01 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 ETS86490.1 - 0.03 13.8 0.0 0.061 12.7 0.0 1.5 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 ETS86490.1 - 0.035 13.8 0.1 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 ETS86490.1 - 0.18 11.9 0.0 0.3 11.2 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.6 ETS86490.1 - 0.2 11.4 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MRP-L28 PF09812.9 ETS86491.1 - 5.2e-06 26.7 0.8 7.7e-06 26.1 0.8 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Cmyb_C PF09316.10 ETS86491.1 - 0.12 12.0 0.4 0.23 11.1 0.4 1.4 1 0 0 1 1 1 0 C-myb, C-terminal HET PF06985.11 ETS86492.1 - 0.0012 19.3 0.0 0.0037 17.6 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Caps_synth PF05704.12 ETS86493.1 - 7.3e-08 32.1 0.1 2.9e-07 30.2 0.1 1.9 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 ETS86493.1 - 3.2e-05 24.5 0.0 6.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3806 PF12713.7 ETS86493.1 - 0.017 14.9 0.2 3 7.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3806) DUF4044 PF13253.6 ETS86493.1 - 0.21 11.1 0.1 0.47 10.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) FTA2 PF13095.6 ETS86495.1 - 7.1e-47 159.8 0.0 1.1e-46 159.2 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 ETS86495.1 - 0.014 14.7 0.0 4.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain FYVE PF01363.21 ETS86496.1 - 2.9e-21 75.4 1.6 2.9e-21 75.4 1.6 2.9 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 ETS86496.1 - 6.4e-07 29.6 3.7 6.4e-07 29.6 3.7 3.8 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.6 ETS86496.1 - 5.2e-06 26.2 1.4 5.2e-06 26.2 1.4 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ETS86496.1 - 0.00017 21.2 2.9 0.00017 21.2 2.9 2.7 3 0 0 3 3 3 1 RING-like zinc finger Rad50_zn_hook PF04423.14 ETS86496.1 - 0.00066 19.5 1.5 0.56 10.1 0.3 2.6 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-C3HC4 PF00097.25 ETS86496.1 - 0.00097 19.0 1.4 0.00097 19.0 1.4 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS86496.1 - 0.0038 17.2 2.5 0.0038 17.2 2.5 3.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.7 ETS86496.1 - 0.018 15.3 3.4 0.018 15.3 3.4 3.4 3 0 0 3 3 3 0 RING-H2 zinc finger domain zf-piccolo PF05715.13 ETS86496.1 - 0.025 14.7 7.8 0.21 11.8 3.6 2.7 2 0 0 2 2 2 0 Piccolo Zn-finger zf-RING-like PF08746.11 ETS86496.1 - 0.025 14.9 1.9 0.025 14.9 1.9 2.8 3 0 0 3 3 1 0 RING-like domain zf-HC5HC2H PF13771.6 ETS86496.1 - 1.9 8.8 11.2 0.39 11.0 0.2 3.2 3 0 0 3 3 3 0 PHD-like zinc-binding domain Prok-RING_4 PF14447.6 ETS86496.1 - 5.1 7.1 19.8 1.4 8.8 0.4 4.3 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 Exo_endo_phos PF03372.23 ETS86497.1 - 2.1e-09 37.3 0.1 3.2e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Fungal_lectin PF07938.12 ETS86498.1 - 3.1e-06 26.8 1.4 0.026 13.9 0.3 2.4 2 0 0 2 2 2 2 Fungal fucose-specific lectin Gly-zipper_Omp PF13488.6 ETS86498.1 - 0.16 12.0 5.0 5.6 7.0 0.6 2.5 2 0 0 2 2 2 0 Glycine zipper DUF4834 PF16118.5 ETS86498.1 - 0.25 12.3 1.7 5.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Rick_17kDa_Anti PF05433.15 ETS86498.1 - 5.8 6.9 11.2 0.32 10.9 0.9 2.9 3 0 0 3 3 3 0 Glycine zipper 2TM domain GalKase_gal_bdg PF10509.9 ETS86499.1 - 4.9e-20 70.8 0.0 8.4e-20 70.1 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 ETS86499.1 - 1.5e-13 50.9 0.0 4.6e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 ETS86499.1 - 9.1e-13 48.2 1.9 2.1e-12 47.1 1.9 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain HTH_3 PF01381.22 ETS86499.1 - 0.054 13.6 1.2 10 6.3 0.4 3.5 3 1 1 4 4 4 0 Helix-turn-helix Sigma70_r4_2 PF08281.12 ETS86499.1 - 0.23 11.2 0.4 1.9 8.2 0.1 2.3 1 1 1 2 2 2 0 Sigma-70, region 4 AMP-binding PF00501.28 ETS86501.1 - 1.9e-74 250.8 0.0 2.8e-74 250.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS86501.1 - 0.00011 23.1 0.0 0.00033 21.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sulfotransfer_4 PF17784.1 ETS86501.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain NAD_binding_6 PF08030.12 ETS86501.1 - 0.032 14.4 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 ETS86501.1 - 0.05 13.7 4.0 0.051 13.7 2.2 2.1 1 1 1 2 2 2 0 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 ETS86501.1 - 0.057 14.1 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Cytochrom_B561 PF03188.16 ETS86501.1 - 0.25 11.5 5.1 4.1 7.5 0.4 2.7 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 ECH_1 PF00378.20 ETS86502.1 - 1.6e-65 220.9 0.4 9.5e-61 205.3 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ETS86502.1 - 6.4e-30 104.8 0.1 1e-29 104.1 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 ETS86502.1 - 0.022 14.7 0.1 0.39 10.7 0.0 2.6 3 0 0 3 3 3 0 Peptidase family S49 Cas_NE0113 PF09623.10 ETS86502.1 - 0.18 11.4 0.0 0.29 10.8 0.0 1.4 1 1 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) bZIP_1 PF00170.21 ETS86503.1 - 7.1e-10 38.8 15.9 1.1e-09 38.2 15.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ETS86503.1 - 1.1e-06 28.6 14.1 2.1e-06 27.7 14.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ETS86503.1 - 0.00097 19.6 10.1 0.00097 19.6 10.1 1.7 2 0 0 2 2 2 1 bZIP Maf transcription factor FAM199X PF15814.5 ETS86503.1 - 0.0062 15.6 1.6 0.0076 15.3 1.6 1.1 1 0 0 1 1 1 1 Protein family FAM199X GBP_C PF02841.14 ETS86503.1 - 0.077 12.4 9.9 0.1 12.0 9.9 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Spc7 PF08317.11 ETS86503.1 - 0.37 9.6 10.2 0.52 9.2 10.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein PI3_PI4_kinase PF00454.27 ETS86504.1 - 4.3e-38 131.6 0.0 1.3e-35 123.4 0.0 2.8 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 ETS86504.1 - 1.9e-25 89.3 0.0 4.3e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Proteasome PF00227.26 ETS86505.1 - 3.1e-30 105.1 0.8 2.5e-29 102.1 0.8 2.1 1 1 0 1 1 1 1 Proteasome subunit YTH PF04146.15 ETS86506.1 - 1.2e-63 214.0 0.0 2e-63 213.2 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 ETS86506.1 - 0.0031 17.3 0.0 0.013 15.3 0.0 2.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP20 PF00011.21 ETS86507.1 - 1.3e-18 67.1 0.5 2.1e-13 50.3 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ETS86507.1 - 1.3e-05 24.6 0.0 0.0079 15.7 0.0 2.2 2 0 0 2 2 2 2 HSP20-like domain found in ArsA Autophagy_N PF03986.13 ETS86507.1 - 0.031 14.2 1.3 0.056 13.4 0.0 1.8 1 1 1 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain TraG-D_C PF12696.7 ETS86508.1 - 0.074 13.0 2.5 0.12 12.4 2.5 1.2 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG IMUP PF15761.5 ETS86508.1 - 0.49 11.1 8.6 0.98 10.1 8.6 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein GDPD PF03009.17 ETS86509.1 - 3.3e-46 158.1 0.0 7.2e-46 157.0 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 ETS86509.1 - 5.5e-19 68.6 0.0 9.5e-10 38.9 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS86509.1 - 9.6e-12 44.0 1.0 0.00051 20.3 0.0 6.9 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 ETS86509.1 - 2.8e-11 43.3 1.1 0.0031 17.9 0.0 6.4 6 0 0 6 6 6 2 Ankyrin repeat 2OG-FeII_Oxy PF03171.20 ETS86509.1 - 6.7e-11 42.6 0.0 1.6e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_5 PF13857.6 ETS86509.1 - 8.4e-11 41.9 1.8 1.4e-05 25.2 0.0 5.5 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS86509.1 - 1.9e-07 31.5 0.1 0.00035 21.1 0.0 4.4 2 2 2 4 4 4 2 Ankyrin repeats (many copies) DIOX_N PF14226.6 ETS86509.1 - 1e-05 26.3 0.0 2.2e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal EPO_TPO PF00758.18 ETS86509.1 - 0.0097 15.9 1.7 0.032 14.3 1.7 1.9 1 0 0 1 1 1 1 Erythropoietin/thrombopoietin ALF PF03752.13 ETS86509.1 - 0.018 15.0 0.1 0.048 13.6 0.1 1.7 1 0 0 1 1 1 0 Short repeats of unknown function G-alpha PF00503.20 ETS86511.1 - 8.6e-73 245.5 2.3 8.6e-73 245.5 2.3 1.8 2 0 0 2 2 2 1 G-protein alpha subunit Arf PF00025.21 ETS86511.1 - 1.2e-10 41.2 0.3 3.6e-06 26.5 0.2 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.6 ETS86511.1 - 0.00079 19.1 0.0 0.0023 17.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 ETS86511.1 - 0.0053 16.2 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family ABC_tran PF00005.27 ETS86511.1 - 0.0095 16.5 0.0 0.035 14.6 0.0 2.0 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 ETS86511.1 - 0.01 15.9 0.0 0.54 10.3 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 ETS86511.1 - 0.019 15.1 0.2 0.28 11.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 ETS86511.1 - 0.038 13.4 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein NOG1 PF06858.14 ETS86511.1 - 0.052 13.3 0.1 0.16 11.8 0.1 1.9 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) NACHT PF05729.12 ETS86511.1 - 0.066 13.1 0.0 6.3 6.7 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 ETS86511.1 - 0.15 12.5 0.4 1 9.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain ADH_N PF08240.12 ETS86512.1 - 1.7e-06 27.9 0.0 3.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS86512.1 - 2.4e-06 27.6 1.9 3.6e-06 27.0 1.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TPR_10 PF13374.6 ETS86513.1 - 1.4e-36 123.3 0.1 2.9e-11 42.8 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat SesA PF17107.5 ETS86513.1 - 2.5e-35 121.3 0.1 7.3e-35 119.8 0.1 1.9 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_12 PF13424.6 ETS86513.1 - 3.7e-34 116.9 0.3 3.2e-16 59.4 0.0 4.3 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 ETS86513.1 - 7.4e-07 28.7 0.7 0.54 10.2 0.5 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ETS86513.1 - 1.5e-06 28.0 0.4 0.0055 16.8 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 ETS86513.1 - 2.9e-06 26.9 0.1 0.37 10.9 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.22 ETS86513.1 - 0.00024 20.4 0.0 0.32 10.2 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain TPR_2 PF07719.17 ETS86513.1 - 0.00055 19.8 0.9 3.3 8.0 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 ETS86513.1 - 0.0021 18.7 0.1 18 6.5 0.1 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 ETS86513.1 - 0.0037 17.7 0.0 0.021 15.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Pectinesterase PF01095.19 ETS86514.1 - 1e-145 484.1 79.3 3.8e-44 150.6 5.5 7.0 7 1 0 7 7 7 5 Pectinesterase p450 PF00067.22 ETS86515.1 - 2.7e-08 33.0 0.0 6.6e-07 28.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Methyltransf_2 PF00891.18 ETS86516.1 - 2.7e-23 82.4 0.0 4.5e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain HEAT_2 PF13646.6 ETS86517.1 - 4e-11 43.1 7.5 2.9e-07 30.8 3.5 3.1 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 ETS86517.1 - 5.5e-08 32.4 1.9 0.051 13.8 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 ETS86517.1 - 6.4e-05 23.4 4.9 0.028 14.9 0.4 4.0 3 2 1 4 4 4 3 HEAT-like repeat HEAT_PBS PF03130.16 ETS86517.1 - 0.00018 21.9 1.7 0.065 13.9 0.3 3.6 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat Arm PF00514.23 ETS86517.1 - 0.00085 19.3 0.2 0.086 12.9 0.0 3.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 ETS86517.1 - 0.012 14.2 1.1 1.4 7.4 0.1 2.4 1 1 1 2 2 2 0 Adaptin N terminal region SRP1_TIP1 PF00660.17 ETS86517.1 - 0.022 14.8 0.1 0.11 12.5 0.0 2.2 3 0 0 3 3 3 0 Seripauperin and TIP1 family Cohesin_HEAT PF12765.7 ETS86517.1 - 0.37 11.1 3.9 16 5.9 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 ETS86518.1 - 6.2e-23 78.9 0.9 0.021 15.0 0.0 7.2 6 0 0 6 6 6 6 HEAT repeat HEAT_2 PF13646.6 ETS86518.1 - 2.8e-22 78.9 5.7 2.2e-07 31.2 0.0 4.3 4 0 0 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 ETS86518.1 - 8.4e-14 51.7 5.1 0.0013 19.2 0.0 5.9 3 2 2 5 5 5 4 HEAT-like repeat Cohesin_HEAT PF12765.7 ETS86518.1 - 1.9e-09 37.6 9.4 0.012 16.0 0.0 5.8 6 0 0 6 6 5 3 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 ETS86518.1 - 3.2e-06 27.3 1.6 0.058 13.4 0.3 4.2 2 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ETS86518.1 - 1.6e-05 25.4 0.1 8.1 7.1 0.0 5.1 2 1 3 5 5 5 1 Vacuolar 14 Fab1-binding region API5 PF05918.11 ETS86518.1 - 0.014 14.2 3.7 4.8 5.9 0.1 3.8 2 1 2 4 4 4 0 Apoptosis inhibitory protein 5 (API5) EHN PF06441.12 ETS86518.1 - 0.02 15.3 2.1 4.4 7.7 0.2 3.6 3 1 1 4 4 3 0 Epoxide hydrolase N terminus Npa1 PF11707.8 ETS86518.1 - 0.046 13.1 0.1 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Ribosome 60S biogenesis N-terminal Arm PF00514.23 ETS86518.1 - 0.11 12.5 0.0 51 4.1 0.0 3.8 4 0 0 4 4 3 0 Armadillo/beta-catenin-like repeat Herpes_UL79 PF03049.14 ETS86518.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 UL79 family CFAP91 PF14738.6 ETS86518.1 - 0.16 12.0 6.5 4.2 7.4 0.3 3.6 2 1 1 3 3 3 0 Cilia- and flagella-associated protein 91 Nipped-B_C PF12830.7 ETS86518.1 - 0.19 11.7 0.4 2.5 8.0 0.2 2.5 1 1 1 2 2 2 0 Sister chromatid cohesion C-terminus DNA_alkylation PF08713.11 ETS86518.1 - 0.23 11.2 2.5 5.5 6.6 0.0 2.6 2 1 0 2 2 2 0 DNA alkylation repair enzyme F-box-like PF12937.7 ETS86518.1 - 0.24 11.3 4.0 1.9e+02 2.0 0.1 5.4 7 0 0 7 7 7 0 F-box-like DUF2235 PF09994.9 ETS86519.1 - 6.7e-62 209.4 0.0 7.7e-61 206.0 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) HET PF06985.11 ETS86520.1 - 4.8e-31 108.1 0.1 9.6e-31 107.1 0.1 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aldo_ket_red PF00248.21 ETS86521.1 - 2.4e-50 171.4 0.0 2.7e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 ETS86522.1 - 8.3e-44 149.4 0.0 1.3e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS86522.1 - 1.9e-35 122.6 0.1 2.4e-35 122.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS86522.1 - 8.4e-11 42.1 0.1 1.5e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS86522.1 - 3.4e-08 33.3 0.1 9.6e-08 31.8 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ETS86522.1 - 0.00033 19.8 0.0 0.00054 19.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ETS86522.1 - 0.0012 18.3 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ETS86522.1 - 0.0099 15.0 0.1 0.014 14.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 ETS86522.1 - 0.027 13.8 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) FAD_binding_4 PF01565.23 ETS86523.1 - 2e-20 73.0 0.5 3.1e-20 72.3 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain DUF3425 PF11905.8 ETS86524.1 - 3.5e-19 69.0 0.2 7.4e-19 67.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) zf-C2H2_jaz PF12171.8 ETS86525.1 - 1.1e-15 57.4 13.4 9e-06 25.8 2.5 5.5 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ETS86525.1 - 2.1e-12 47.2 19.7 0.0053 17.1 3.6 5.8 2 2 4 6 6 6 4 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 ETS86525.1 - 2.4e-12 46.6 28.6 0.13 13.1 0.5 7.2 7 0 0 7 7 7 5 C2H2-type zinc finger zf-met PF12874.7 ETS86525.1 - 5.3e-12 45.7 10.9 0.0016 18.8 0.5 5.0 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ETS86525.1 - 5.2e-09 36.1 29.0 0.014 15.8 2.2 6.4 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 ETS86525.1 - 2.9e-06 27.4 32.6 0.029 14.8 1.0 7.1 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ETS86525.1 - 9.5e-05 22.3 27.1 0.041 13.9 0.1 5.9 7 0 0 7 7 6 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ETS86525.1 - 0.0025 18.1 15.5 0.33 11.3 0.3 4.4 2 2 2 4 4 4 2 C2H2-type zinc ribbon zf-DBF PF07535.12 ETS86525.1 - 0.0033 17.5 14.4 0.11 12.6 0.9 4.8 4 0 0 4 4 4 2 DBF zinc finger zf-C2H2_aberr PF17017.5 ETS86525.1 - 0.062 13.4 12.1 1.1 9.4 2.5 3.2 2 1 1 3 3 3 0 Aberrant zinc-finger zf-C2H2_9 PF16293.5 ETS86525.1 - 0.076 12.9 6.9 13 5.7 0.1 4.9 4 1 1 5 5 5 0 C2H2 type zinc-finger (1 copy) FOXP-CC PF16159.5 ETS86525.1 - 3.6 8.3 12.5 5.4 7.7 0.8 3.9 3 2 1 4 4 4 0 FOXP coiled-coil domain zf-MYST PF17772.1 ETS86525.1 - 6.6 6.4 7.5 1 9.0 1.0 2.8 3 0 0 3 3 3 0 MYST family zinc finger domain Sugar_tr PF00083.24 ETS86526.1 - 1.7e-84 284.3 30.6 2.1e-84 284.0 30.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS86526.1 - 1.6e-20 73.4 43.3 1e-17 64.1 23.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS86526.1 - 0.0009 18.2 9.3 0.0009 18.2 9.3 2.2 2 0 0 2 2 2 1 MFS_1 like family DUF4381 PF14316.6 ETS86526.1 - 0.14 12.4 0.9 1.7 8.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Beta-APP PF03494.13 ETS86526.1 - 0.23 11.3 1.6 0.59 10.0 1.6 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) p450 PF00067.22 ETS86527.1 - 9.5e-52 176.3 0.0 1.4e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF924 PF06041.11 ETS86528.1 - 4.3e-47 160.6 0.1 5.1e-47 160.3 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) MFS_1 PF07690.16 ETS86530.1 - 1.4e-23 83.4 43.1 1.4e-23 83.4 43.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS86530.1 - 1e-05 25.1 8.9 1e-05 25.1 8.9 2.9 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB DUF1180 PF06679.12 ETS86530.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Saf_2TM PF18303.1 ETS86530.1 - 0.51 9.9 4.0 11 5.6 0.1 2.7 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain DUF4131 PF13567.6 ETS86530.1 - 8.4 6.0 15.1 0.34 10.6 0.7 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) TMEM43 PF07787.12 ETS86530.1 - 9.9 5.5 7.0 7.5 5.9 5.0 1.8 1 1 0 1 1 1 0 Transmembrane protein 43 Peptidase_M20 PF01546.28 ETS86531.1 - 4.2e-29 101.7 0.3 1.1e-28 100.4 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ETS86531.1 - 8.4e-06 25.7 0.0 3.6e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ETS86531.1 - 0.0067 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 ETS86532.1 - 1.4e-26 92.9 0.0 2.8e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 ETS86532.1 - 5.7e-18 65.3 0.0 1.2e-17 64.3 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ETS86532.1 - 8.9e-14 51.3 0.4 2.6e-13 49.8 0.0 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 ETS86532.1 - 0.14 11.9 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 MFS_1 PF07690.16 ETS86533.1 - 1.1e-24 87.1 31.3 1.1e-24 87.1 31.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS86533.1 - 0.00012 21.0 2.5 0.00012 21.0 2.5 2.3 1 1 1 2 2 2 2 MFS_1 like family TauD PF02668.16 ETS86534.1 - 1.9e-21 77.0 1.1 4e-21 76.0 1.1 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AAA_16 PF13191.6 ETS86535.1 - 4.3e-06 27.2 0.3 0.00027 21.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 ETS86535.1 - 2e-05 24.6 1.9 7.7e-05 22.7 1.9 2.1 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ETS86535.1 - 0.00025 21.3 0.0 0.00094 19.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain SesA PF17107.5 ETS86535.1 - 0.0003 21.0 3.5 0.00045 20.4 0.8 2.5 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases YcxB PF14317.6 ETS86535.1 - 0.013 15.1 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 YcxB-like protein AAA PF00004.29 ETS86535.1 - 0.022 15.2 0.0 0.24 11.8 0.0 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ETS86535.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AMP-binding PF00501.28 ETS86536.1 - 1.8e-34 119.1 0.0 3.3e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ETS86536.1 - 2.2e-24 86.0 0.0 3.7e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 ETS86536.1 - 3.2e-08 33.3 0.0 5.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 ETS86536.1 - 0.00031 21.0 0.2 0.0025 18.1 0.1 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site KR PF08659.10 ETS86536.1 - 0.033 14.1 0.1 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 ETS86536.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Myb_DNA-binding PF00249.31 ETS86537.1 - 0.00084 19.5 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pinin_SDK_N PF04697.13 ETS86537.1 - 0.24 12.0 1.1 0.47 11.1 0.3 1.7 2 0 0 2 2 2 0 pinin/SDK conserved region ketoacyl-synt PF00109.26 ETS86538.1 - 3.7e-72 242.9 0.0 1e-71 241.5 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ETS86538.1 - 6.2e-34 116.5 0.0 1.3e-33 115.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 ETS86538.1 - 6.2e-24 83.7 0.0 1.9e-23 82.1 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain PP-binding PF00550.25 ETS86538.1 - 1.4e-21 76.6 9.7 1.2e-12 48.0 1.3 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Acyl_transf_1 PF00698.21 ETS86538.1 - 7.3e-21 75.0 0.0 1.5e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 ETS86538.1 - 4.3e-17 62.3 0.0 6.7e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 ETS86538.1 - 2.9e-14 53.6 0.0 8.1e-14 52.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.13 ETS86538.1 - 9.5e-11 41.9 0.0 8.1e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_23 PF13489.6 ETS86538.1 - 2.8e-08 33.8 0.0 6.9e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS86538.1 - 6.1e-08 33.3 0.0 1.9e-07 31.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS86538.1 - 4e-07 29.9 0.0 9.2e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ETS86538.1 - 5.6e-07 30.0 0.0 1.5e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 ETS86538.1 - 4.1e-06 27.4 0.0 1.1e-05 25.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.7 ETS86538.1 - 7e-05 23.5 1.0 7e-05 23.5 1.0 3.3 3 1 0 3 3 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ETS86538.1 - 0.0023 17.5 0.1 0.52 9.8 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thiolase_N PF00108.23 ETS86538.1 - 0.0026 17.2 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 ETS86538.1 - 0.006 16.3 0.0 0.018 14.8 0.0 1.7 1 1 0 1 1 1 1 Lysine methyltransferase PHB_depo_C PF06850.11 ETS86538.1 - 0.088 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 PHB de-polymerase C-terminus Methyltransf_33 PF10017.9 ETS86538.1 - 0.097 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent p450 PF00067.22 ETS86539.1 - 6.5e-56 190.0 0.0 8.6e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS86540.1 - 4.2e-73 246.7 0.0 5.2e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.8 ETS86541.1 - 1.4e-87 294.5 0.5 5.9e-76 256.2 0.0 2.9 3 0 0 3 3 3 3 Tryptophan dimethylallyltransferase FAD_binding_4 PF01565.23 ETS86542.1 - 1.4e-19 70.2 0.4 6.8e-19 68.0 1.1 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 ETS86542.1 - 0.00082 19.4 0.0 0.0019 18.2 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.25 ETS86543.1 - 1.8e-20 73.3 1.2 1.1e-18 67.4 0.8 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 ETS86543.1 - 1.4e-12 47.9 0.1 1.9e-12 47.4 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ETS86543.1 - 2.5e-10 40.3 0.8 3e-09 36.8 0.4 2.1 1 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF2322 PF10084.9 ETS86543.1 - 0.071 13.2 0.0 0.84 9.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) Fungal_trans_2 PF11951.8 ETS86544.1 - 0.00037 19.4 0.2 0.00051 19.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 ETS86545.1 - 3.4e-27 95.2 0.0 1e-25 90.4 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS86545.1 - 5e-20 72.1 0.0 1.1e-18 67.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS86545.1 - 2.7e-08 33.9 0.0 3.5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS86545.1 - 6.4e-07 29.1 0.0 8.7e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS86545.1 - 0.0032 17.4 0.1 0.004 17.1 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS86545.1 - 0.065 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family SDA1 PF05285.12 ETS86548.1 - 0.059 12.8 15.4 0.065 12.7 15.4 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 ETS86548.1 - 0.22 10.3 1.1 0.19 10.4 1.1 1.1 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 ETS86548.1 - 0.74 9.1 18.0 1.2 8.4 18.0 1.4 1 0 0 1 1 1 0 NOA36 protein DUF913 PF06025.12 ETS86548.1 - 3.4 6.6 5.0 3.8 6.4 5.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 ETS86548.1 - 6.2 7.0 9.4 8.6 6.5 9.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RNA_pol_3_Rpc31 PF11705.8 ETS86548.1 - 7.1 6.8 25.1 11 6.2 25.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CobT PF06213.12 ETS86548.1 - 8.8 5.6 22.7 12 5.2 22.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FOXP-CC PF16159.5 ETS86549.1 - 4.4 8.0 9.7 3 8.5 0.1 2.8 1 1 2 3 3 3 0 FOXP coiled-coil domain FOXP-CC PF16159.5 ETS86550.1 - 0.062 13.9 4.4 7.2 7.3 0.0 2.9 1 1 1 2 2 2 0 FOXP coiled-coil domain AA_permease PF00324.21 ETS86551.1 - 9.9e-109 364.1 42.6 1.2e-108 363.8 42.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS86551.1 - 2.1e-24 86.1 49.5 4.9e-24 84.9 49.4 1.5 1 1 0 1 1 1 1 Amino acid permease DUF3445 PF11927.8 ETS86552.1 - 3.8e-53 180.4 0.0 4.5e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Fungal_trans_2 PF11951.8 ETS86553.1 - 1.9e-34 119.2 7.2 2.4e-34 118.8 7.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS86553.1 - 9.4e-08 32.1 4.1 9.4e-08 32.1 4.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 ETS86554.1 - 8.2e-19 68.4 0.0 1.2e-18 67.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Init_tRNA_PT PF04179.12 ETS86554.1 - 0.17 12.2 0.0 0.27 11.5 0.0 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain C2 PF00168.30 ETS86555.1 - 7.2e-27 93.7 0.1 3.9e-14 52.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain 2-Hacid_dh_C PF02826.19 ETS86556.1 - 2.1e-42 144.5 0.0 6.8e-42 142.8 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS86556.1 - 1.7e-21 76.3 0.0 2.1e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 ETS86556.1 - 0.011 16.3 0.1 0.036 14.6 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain IlvN PF07991.12 ETS86556.1 - 0.039 13.5 0.4 0.37 10.4 0.1 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 ETS86556.1 - 0.17 12.5 2.6 11 6.7 0.9 2.8 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent CUE PF02845.16 ETS86557.1 - 7.8e-10 38.3 0.0 1.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 CUE domain HEPN_RnaseLS PF18869.1 ETS86559.1 - 0.054 13.6 0.1 0.63 10.2 0.1 2.2 2 0 0 2 2 2 0 RnaseLS-like HEPN DUF5560 PF17715.1 ETS86559.1 - 0.15 11.5 0.4 1.1 8.6 0.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5560) Lentiviral_Tat PF02998.14 ETS86559.1 - 1.8 8.7 4.2 0.41 10.7 0.3 2.0 2 0 0 2 2 2 0 Lentiviral Tat protein Kelch_5 PF13854.6 ETS86561.1 - 5e-13 48.7 4.8 9.5e-07 28.7 0.1 4.9 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 ETS86561.1 - 1.5e-09 37.7 7.6 0.046 13.7 0.1 6.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 ETS86561.1 - 1.9e-07 31.1 8.8 0.024 14.9 0.1 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 ETS86561.1 - 2.7e-05 24.3 23.0 0.053 13.8 0.4 6.7 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.25 ETS86561.1 - 0.00035 20.1 10.1 0.1 12.2 0.1 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 ETS86561.1 - 0.001 18.9 6.6 0.15 12.0 0.0 4.8 6 0 0 6 6 6 2 Kelch motif SKG6 PF08693.10 ETS86561.1 - 0.034 13.6 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain OPT PF03169.15 ETS86562.1 - 3.7e-153 511.4 33.8 4.4e-153 511.2 33.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein HTH_Tnp_Tc5 PF03221.16 ETS86562.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain SET PF00856.28 ETS86564.1 - 2.1e-13 51.0 0.0 9.1e-13 48.9 0.0 2.0 2 1 0 2 2 2 1 SET domain XkdW PF09636.10 ETS86566.1 - 0.18 11.9 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 XkdW protein HET PF06985.11 ETS86567.1 - 7.3e-29 101.0 0.9 1.1e-28 100.4 0.9 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ETS86568.1 - 1.2e-27 97.1 0.0 2.1e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TPR_10 PF13374.6 ETS86569.1 - 0.075 12.9 1.0 2.1 8.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ETS86569.1 - 0.076 13.3 2.1 2.4 8.5 1.2 3.3 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF1515 PF07439.11 ETS86569.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) CHAT PF12770.7 ETS86570.1 - 1.6e-10 40.8 0.0 2.3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 CHAT domain Pro-kuma_activ PF09286.11 ETS86571.1 - 0.054 13.8 0.1 8.6 6.6 0.0 3.0 2 1 1 3 3 3 0 Pro-kumamolisin, activation domain CMAS PF02353.20 ETS86571.1 - 0.099 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TMEM100 PF16311.5 ETS86574.1 - 0.0013 18.3 1.0 0.083 12.5 0.5 2.4 2 0 0 2 2 2 2 Transmembrane protein 100 HET PF06985.11 ETS86575.1 - 3.6e-32 111.7 0.0 6.2e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Porin_5 PF16930.5 ETS86575.1 - 0.11 10.9 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Putative porin Ank_4 PF13637.6 ETS86576.1 - 0.015 15.8 0.1 0.92 10.2 0.1 3.1 2 1 1 3 3 3 0 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 ETS86576.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.6 1 0 0 1 1 1 0 Phosphorylase superfamily PNP_UDP_1 PF01048.20 ETS86577.1 - 9.2e-10 38.2 0.6 5.1e-09 35.7 0.6 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT_sigma PF17106.5 ETS86577.1 - 0.32 11.2 2.2 0.36 11.0 0.5 2.0 2 0 0 2 2 2 0 Sigma domain on NACHT-NTPases Ank_2 PF12796.7 ETS86578.1 - 4.9e-60 200.1 9.6 6.4e-13 49.1 0.1 6.7 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS86578.1 - 1.3e-43 146.8 10.7 2.4e-05 24.8 0.0 10.2 3 2 9 12 12 11 11 Ankyrin repeats (many copies) Ank PF00023.30 ETS86578.1 - 5.1e-42 140.5 25.9 0.00063 20.1 0.0 13.5 13 0 0 13 13 13 10 Ankyrin repeat Ank_3 PF13606.6 ETS86578.1 - 5.3e-37 121.6 9.1 0.0011 19.2 0.0 13.7 13 0 0 13 13 13 7 Ankyrin repeat Ank_5 PF13857.6 ETS86578.1 - 9.1e-30 102.3 10.2 0.0036 17.6 0.1 11.4 1 1 11 12 12 12 8 Ankyrin repeats (many copies) NACHT PF05729.12 ETS86578.1 - 1.9e-07 31.2 0.0 4.3e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS86578.1 - 0.00066 20.1 0.0 0.0021 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS86578.1 - 0.0086 16.4 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 ETS86578.1 - 0.019 14.9 0.0 0.43 10.5 0.0 2.9 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 RNaseH_pPIWI_RE PF13032.6 ETS86578.1 - 0.035 14.0 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 RNaseH domain of pPIWI_RE ABC_tran PF00005.27 ETS86578.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 ETS86578.1 - 0.061 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 ETS86578.1 - 0.066 12.4 0.3 3.4 6.8 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.6 ETS86578.1 - 0.069 13.7 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT_sigma PF17106.5 ETS86578.1 - 0.075 13.2 10.9 0.04 14.1 7.5 2.3 2 0 0 2 2 2 0 Sigma domain on NACHT-NTPases RNA_helicase PF00910.22 ETS86578.1 - 0.096 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mic1 PF07035.12 ETS86578.1 - 0.13 11.9 0.0 53 3.5 0.0 4.9 6 0 0 6 6 6 0 Colon cancer-associated protein Mic1-like MFS_1 PF07690.16 ETS86579.1 - 5.5e-18 65.0 56.5 5.5e-16 58.4 30.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS86579.1 - 0.0017 17.3 13.5 0.0017 17.3 13.5 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter Peptidase_M56 PF05569.11 ETS86579.1 - 0.049 12.8 0.8 0.21 10.7 0.1 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 Protocadherin PF08374.11 ETS86579.1 - 0.07 13.1 0.3 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 Protocadherin Bac_export_2 PF01312.19 ETS86579.1 - 0.14 11.3 6.1 2.9 7.0 0.0 3.1 2 1 0 3 3 3 0 FlhB HrpN YscU SpaS Family Phage_holin_7_1 PF16081.5 ETS86579.1 - 0.69 10.1 7.9 0.73 10.0 0.6 2.6 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF5336 PF17270.2 ETS86579.1 - 1.7 8.2 6.6 9.4 5.8 0.0 3.5 3 1 0 3 3 3 0 Family of unknown function (DUF5336) DUF1182 PF06681.13 ETS86581.1 - 0.14 11.7 0.2 0.17 11.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) DUF4291 PF14124.6 ETS86582.1 - 3.8e-68 228.9 0.1 4.4e-68 228.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) SKG6 PF08693.10 ETS86582.1 - 2.6 7.5 5.3 4.2 6.8 5.3 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HTH_11 PF08279.12 ETS86584.1 - 0.15 12.1 0.1 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 HTH domain Ribosomal_L10 PF00466.20 ETS86585.1 - 4e-23 81.4 0.1 9.6e-23 80.2 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 ETS86585.1 - 1.4e-22 79.5 0.0 2.4e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 ETS86585.1 - 1.8e-21 76.5 3.5 1.8e-21 76.5 3.5 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein VirE_N PF08800.10 ETS86585.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 VirE N-terminal domain MutS_V PF00488.21 ETS86586.1 - 2.2e-68 230.0 0.1 4.2e-68 229.1 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ETS86586.1 - 3.7e-49 167.6 2.8 5.8e-49 166.9 2.8 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 ETS86586.1 - 1.5e-19 70.3 0.0 6.3e-19 68.3 0.0 2.1 3 0 0 3 3 3 1 MutS domain I MutS_II PF05188.17 ETS86586.1 - 2.1e-08 34.5 0.0 1.1e-07 32.2 0.0 2.2 2 0 0 2 2 2 1 MutS domain II IL11 PF07400.11 ETS86586.1 - 0.044 13.4 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Interleukin 11 EccE PF11203.8 ETS86586.1 - 0.72 10.2 4.1 5.6 7.4 1.5 3.3 3 0 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE NUC130_3NT PF08158.12 ETS86586.1 - 1.2 9.5 3.3 6.8 7.1 0.4 3.4 3 0 0 3 3 3 0 NUC130/3NT domain DnaJ_C PF01556.18 ETS86587.1 - 1.8e-38 132.0 0.0 2.3e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ETS86587.1 - 4.3e-25 87.6 4.1 4.3e-25 87.6 4.1 1.7 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ETS86587.1 - 1.8e-15 57.1 19.2 3.3e-15 56.2 19.2 1.5 1 0 0 1 1 1 1 DnaJ central domain zinc_ribbon_9 PF14369.6 ETS86587.1 - 0.13 12.6 0.4 32 4.9 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon HypA PF01155.19 ETS86587.1 - 0.41 10.7 9.8 1 9.4 2.2 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 ETS86587.1 - 0.89 9.6 7.3 7.3 6.7 1.4 2.3 1 1 1 2 2 2 0 zinc-ribbons DZR PF12773.7 ETS86587.1 - 0.96 9.5 6.7 7.8 6.6 0.5 2.3 2 0 0 2 2 2 0 Double zinc ribbon DUF2614 PF11023.8 ETS86587.1 - 2.7 8.1 6.9 17 5.6 0.4 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain Pkinase PF00069.25 ETS86588.1 - 6.4e-35 120.8 0.0 4.8e-20 72.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS86588.1 - 3.3e-14 52.8 0.0 3.4e-13 49.5 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ETS86588.1 - 4.3e-06 26.8 0.0 7.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ETS86588.1 - 0.013 14.9 0.0 2 7.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like CPSF_A PF03178.15 ETS86589.1 - 0.00017 21.0 0.0 0.0003 20.2 0.0 1.4 1 1 0 1 1 1 1 CPSF A subunit region WD40 PF00400.32 ETS86589.1 - 0.001 19.9 3.5 0.22 12.5 0.0 4.6 4 1 0 4 4 4 1 WD domain, G-beta repeat VCBS PF13517.6 ETS86589.1 - 0.0048 17.4 0.1 2.4 8.8 0.0 3.3 4 0 0 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella bZIP_2 PF07716.15 ETS86590.1 - 0.00072 19.6 4.3 0.0012 18.9 4.3 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ETS86590.1 - 0.059 13.5 5.5 0.1 12.7 5.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor Glyco_hydro_38N PF01074.22 ETS86591.1 - 3e-87 292.6 1.6 3e-87 292.6 1.6 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 ETS86591.1 - 1.6e-54 185.3 0.1 4.1e-54 183.9 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 ETS86591.1 - 5.2e-24 84.2 0.0 1.4e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 ETS86591.1 - 5.5e-10 39.2 0.0 1.4e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain BiPBP_C PF06832.12 ETS86591.1 - 0.11 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family CAP_GLY PF01302.25 ETS86592.1 - 4.7e-16 58.6 0.5 9.4e-16 57.6 0.5 1.5 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 ETS86592.1 - 3.5e-09 36.3 11.0 2.1e-05 24.3 1.1 2.6 2 0 0 2 2 2 2 CLIP1 zinc knuckle Uso1_p115_C PF04871.13 ETS86592.1 - 0.0052 17.1 9.3 0.0052 17.1 9.3 3.5 2 1 1 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region HemX PF04375.14 ETS86592.1 - 0.0083 15.4 4.6 0.0083 15.4 4.6 3.1 2 1 1 3 3 3 1 HemX, putative uroporphyrinogen-III C-methyltransferase BLOC1_2 PF10046.9 ETS86592.1 - 0.024 14.9 1.9 0.024 14.9 1.9 3.5 4 0 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 ETS86592.1 - 0.031 14.7 7.5 0.24 11.9 1.2 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF812 PF05667.11 ETS86592.1 - 0.061 12.2 33.6 0.19 10.6 4.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Med4 PF10018.9 ETS86592.1 - 0.065 12.9 19.2 0.42 10.3 3.4 3.5 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 FliD_N PF02465.18 ETS86592.1 - 0.18 12.5 12.0 1.9 9.2 0.2 3.8 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Spc7 PF08317.11 ETS86592.1 - 0.39 9.5 34.9 0.51 9.2 7.4 3.1 2 1 0 3 3 3 0 Spc7 kinetochore protein Fez1 PF06818.15 ETS86592.1 - 0.53 10.7 34.8 6.4 7.2 1.8 3.2 2 1 1 3 3 3 0 Fez1 C1_2 PF03107.16 ETS86592.1 - 0.54 10.6 1.8 29 5.1 0.1 2.3 2 0 0 2 2 2 0 C1 domain Prominin PF05478.11 ETS86592.1 - 3.7 5.4 5.5 6.2 4.7 5.5 1.3 1 0 0 1 1 1 0 Prominin Cauli_AT PF03233.13 ETS86592.1 - 5.8 6.8 8.6 3.8 7.4 1.4 2.8 2 1 1 3 3 3 0 Aphid transmission protein DUF1722 PF08349.11 ETS86593.1 - 0.066 13.5 0.4 1.7 9.0 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1722) Nop14 PF04147.12 ETS86594.1 - 1.7e-286 953.1 33.1 2.1e-286 952.7 33.1 1.1 1 0 0 1 1 1 1 Nop14-like family DUF4187 PF13821.6 ETS86595.1 - 1.3e-22 79.3 4.8 3e-22 78.1 4.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.23 ETS86595.1 - 3.9e-09 36.3 0.2 8.1e-09 35.2 0.2 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ETS86595.1 - 0.026 14.6 0.3 0.14 12.3 0.3 2.3 1 0 0 1 1 1 0 G-patch domain Ald_Xan_dh_C2 PF02738.18 ETS86595.1 - 0.11 10.9 1.8 0.16 10.4 1.8 1.1 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase PPR_2 PF13041.6 ETS86596.1 - 2.7e-07 30.7 0.1 0.38 11.0 0.0 5.8 5 1 0 5 5 5 3 PPR repeat family PPR PF01535.20 ETS86596.1 - 0.018 15.3 8.3 11 6.5 0.2 6.0 7 0 0 7 7 7 0 PPR repeat ORC3_N PF07034.11 ETS86597.1 - 1.1e-41 143.0 7.0 6.7e-39 133.9 4.5 3.1 2 1 0 2 2 2 2 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 ETS86597.1 - 7.2e-30 103.9 0.1 2.8e-17 63.1 0.0 2.7 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal MutS_III PF05192.18 ETS86597.1 - 0.019 15.2 4.3 0.034 14.4 0.4 2.4 1 1 0 2 2 2 0 MutS domain III Cuticle_4 PF15955.5 ETS86598.1 - 0.068 13.9 0.6 0.14 12.8 0.6 1.5 1 0 0 1 1 1 0 Cuticle protein Sec66 PF09802.9 ETS86599.1 - 1.5e-75 252.7 1.3 1.8e-75 252.5 1.3 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 CAF1A PF12253.8 ETS86599.1 - 0.032 14.4 1.4 0.032 14.4 1.4 1.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A Rho_Binding PF08912.11 ETS86599.1 - 0.068 14.0 5.6 0.37 11.6 2.1 2.3 2 0 0 2 2 2 0 Rho Binding OmpH PF03938.14 ETS86599.1 - 0.25 11.7 5.4 0.45 10.9 5.4 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2458 PF10454.9 ETS86599.1 - 0.3 10.7 5.1 0.081 12.6 1.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) RTC PF01137.21 ETS86600.1 - 6.7e-31 107.2 0.4 8.3e-31 106.9 0.4 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 ETS86600.1 - 1.2e-30 106.0 0.3 2.3e-30 105.1 0.3 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF1746 PF08508.10 ETS86601.1 - 3.5e-39 133.7 4.3 5.3e-39 133.1 4.3 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) OSTbeta PF15048.6 ETS86601.1 - 0.012 15.8 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein P5-ATPase PF12409.8 ETS86601.1 - 0.29 11.2 1.4 0.62 10.2 1.4 1.5 1 0 0 1 1 1 0 P5-type ATPase cation transporter tRNA-synt_2d PF01409.20 ETS86602.1 - 5.2e-85 284.8 0.0 7.2e-85 284.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 ETS86602.1 - 6.6e-16 58.4 2.6 1.4e-15 57.3 2.6 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 ETS86602.1 - 2.4e-06 27.2 0.0 0.0057 16.1 0.0 3.1 3 1 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 ETS86602.1 - 5.4e-05 23.1 1.8 0.00019 21.3 1.8 2.0 1 1 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 ETS86602.1 - 5.9e-05 22.3 1.3 0.0027 16.8 0.2 2.9 2 1 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 ETS86602.1 - 0.0016 18.4 0.0 0.0091 16.0 0.0 2.1 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Anp1 PF03452.14 ETS86605.1 - 5.6e-105 350.5 0.0 6.7e-105 350.2 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 ETS86605.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 UQ_con PF00179.26 ETS86606.1 - 6.3e-30 103.7 0.0 7.5e-30 103.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 ETS86606.1 - 0.024 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.6 ETS86606.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 ETS86606.1 - 0.2 11.6 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 ETS86606.1 - 0.2 12.0 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain bZIP_1 PF00170.21 ETS86607.1 - 2.1e-06 27.7 5.1 2.9e-06 27.3 5.1 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ETS86607.1 - 4.3e-06 26.7 4.7 8.9e-06 25.7 4.7 1.5 1 1 0 1 1 1 1 Basic region leucine zipper Golgin_A5 PF09787.9 ETS86607.1 - 0.049 13.1 1.3 0.069 12.6 1.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Phlebovirus_NSM PF07246.11 ETS86607.1 - 0.073 12.4 0.5 0.1 12.0 0.5 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M C8 PF08742.11 ETS86607.1 - 0.12 12.9 0.2 0.24 11.9 0.2 1.5 1 0 0 1 1 1 0 C8 domain CAP_N PF01213.19 ETS86607.1 - 0.79 9.2 8.8 1.3 8.5 8.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 ETS86607.1 - 2.8 8.0 13.7 0.057 13.5 6.9 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator GMC_oxred_N PF00732.19 ETS86609.1 - 3.4e-65 220.3 0.0 4.4e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS86609.1 - 5.9e-30 104.7 0.2 1.2e-29 103.7 0.2 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS86609.1 - 1.1e-06 28.0 0.3 0.0027 16.9 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 ETS86609.1 - 5.6e-06 25.6 0.5 8.8e-06 25.0 0.5 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 ETS86609.1 - 1.1e-05 25.3 3.6 0.00011 21.9 3.4 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ETS86609.1 - 0.00022 20.5 0.1 0.00047 19.5 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 ETS86609.1 - 0.00057 19.2 0.1 0.0053 16.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS86609.1 - 0.00077 19.6 0.0 0.0019 18.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ETS86609.1 - 0.012 14.5 0.3 0.023 13.6 0.1 1.5 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 ETS86609.1 - 0.047 12.4 0.6 0.07 11.8 0.2 1.5 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 ETS86609.1 - 0.056 12.5 0.2 0.099 11.7 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ETS86609.1 - 0.13 11.5 1.3 1.2 8.3 0.3 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 ETS86609.1 - 0.2 12.2 0.9 1 10.0 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-C3HC4_4 PF15227.6 ETS86611.1 - 5.5 7.2 13.1 5.7 7.2 7.9 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 ETS86611.1 - 5.8 7.0 14.1 78 3.3 13.8 2.2 1 1 0 1 1 1 0 zinc-RING finger domain Lactamase_B_3 PF13483.6 ETS86612.1 - 1.8e-06 27.9 0.0 5.8e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain EF-hand_1 PF00036.32 ETS86613.1 - 3.5e-27 91.9 5.6 3.1e-06 26.3 0.0 5.3 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 ETS86613.1 - 2.1e-22 79.3 5.8 3.6e-09 36.9 0.0 3.4 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 ETS86613.1 - 4.9e-22 75.9 7.5 5e-05 22.9 0.3 5.3 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 ETS86613.1 - 7.1e-18 64.2 9.1 1.1e-08 34.8 0.0 5.0 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 ETS86613.1 - 1e-16 59.6 1.8 0.00045 19.6 0.4 4.4 4 0 0 4 4 4 4 EF hand DUF2024 PF09630.10 ETS86613.1 - 0.21 11.5 0.1 0.39 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) ChaC PF04752.12 ETS86614.1 - 1.3e-38 132.8 0.0 1.7e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Unstab_antitox PF09720.10 ETS86614.1 - 1.8 8.7 4.3 5.2 7.2 0.1 2.9 4 0 0 4 4 4 0 Putative addiction module component RRM_1 PF00076.22 ETS86615.1 - 4.9e-23 80.7 0.0 6.2e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ETS86615.1 - 0.0016 18.5 0.0 0.0029 17.7 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 ETS86615.1 - 0.023 14.6 0.0 0.039 13.8 0.0 1.3 1 1 0 1 1 1 0 Occluded RNA-recognition motif HpcH_HpaI PF03328.14 ETS86617.1 - 1.3e-41 142.2 0.2 1.1e-40 139.1 0.0 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 ETS86617.1 - 1.2e-12 47.7 0.0 2.9e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PEPcase_2 PF14010.6 ETS86617.1 - 0.15 10.5 0.0 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Ribosomal_S8 PF00410.19 ETS86618.1 - 7.4e-05 22.7 0.2 6.4 6.7 0.0 3.9 4 0 0 4 4 4 2 Ribosomal protein S8 RTT107_BRCT_5 PF16770.5 ETS86618.1 - 0.00052 19.8 0.0 2.4 8.1 0.0 3.5 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain PASTA PF03793.19 ETS86618.1 - 0.015 15.1 3.3 3.2 7.7 0.2 3.7 4 0 0 4 4 4 0 PASTA domain Arg_repressor PF01316.21 ETS86618.1 - 0.052 13.3 0.6 16 5.4 0.0 3.9 5 0 0 5 5 5 0 Arginine repressor, DNA binding domain DUF4224 PF13986.6 ETS86618.1 - 0.083 12.8 0.0 11 6.0 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4224) Glutaredoxin PF00462.24 ETS86619.1 - 2.2e-15 56.6 0.2 5.8e-15 55.2 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.6 ETS86619.1 - 0.00041 20.7 0.0 0.00085 19.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF3619 PF12279.8 ETS86619.1 - 0.031 14.6 0.4 8.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) Thioredoxin_8 PF13905.6 ETS86619.1 - 0.083 13.2 0.3 1.6 9.2 0.0 2.6 3 1 1 4 4 4 0 Thioredoxin-like PY_rept_46 PF09689.10 ETS86619.1 - 0.77 10.4 3.5 27 5.4 0.8 2.4 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) HlyIII PF03006.20 ETS86622.1 - 2.1e-62 210.7 12.0 2.5e-62 210.5 12.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related Kelch_6 PF13964.6 ETS86622.1 - 0.14 12.5 0.5 32 5.0 0.2 2.9 2 0 0 2 2 2 0 Kelch motif TMA7 PF09072.10 ETS86623.1 - 7.8e-26 90.7 16.3 8.7e-26 90.5 16.3 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.25 ETS86624.1 - 1.7e-52 178.4 0.1 2.3e-52 178.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS86624.1 - 1.7e-23 83.3 0.1 4.4e-23 81.9 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 ETS86624.1 - 0.09 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 ETS86625.1 - 2.8e-54 184.2 0.0 3.6e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS86625.1 - 2.1e-30 105.9 0.0 2.6e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS86625.1 - 0.00049 19.5 0.0 0.0015 17.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ETS86625.1 - 0.00071 19.6 0.0 0.0016 18.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ETS86625.1 - 0.0025 17.2 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ETS86625.1 - 0.017 13.9 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 ETS86625.1 - 0.05 13.2 0.0 0.72 9.4 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ETS86625.1 - 0.088 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 ETS86625.1 - 0.26 10.9 0.0 0.56 9.8 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase ANAPC4_WD40 PF12894.7 ETS86626.1 - 2e-12 47.2 0.0 0.24 11.7 0.0 5.6 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ETS86626.1 - 4.1e-09 36.9 0.0 0.6 11.1 0.0 5.8 4 0 0 4 4 4 2 WD domain, G-beta repeat PGAP1 PF07819.13 ETS86626.1 - 6.5e-06 26.0 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein NACHT PF05729.12 ETS86626.1 - 0.00015 21.8 0.0 0.00039 20.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.14 ETS86626.1 - 0.00031 20.3 0.0 0.00065 19.3 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 ETS86626.1 - 0.00084 20.0 0.0 0.0026 18.4 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.6 ETS86626.1 - 0.026 14.9 0.0 0.075 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain LCAT PF02450.15 ETS86626.1 - 0.058 12.6 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Inv-AAD PF18785.1 ETS86627.1 - 4.6e-58 194.7 0.0 5.5e-58 194.4 0.0 1.0 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 ETS86627.1 - 7.5e-14 51.4 0.0 9.9e-14 51.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 ETS86627.1 - 7.9e-05 22.6 0.0 9.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Fructosamin_kin PF03881.14 ETS86628.1 - 5.3e-41 140.7 0.0 6.9e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 ETS86628.1 - 5.6e-07 29.7 0.0 8.1e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fungal_trans PF04082.18 ETS86629.1 - 1.1e-13 50.9 1.3 2.1e-13 49.9 1.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 ETS86629.1 - 0.0092 16.4 0.5 0.036 14.5 0.5 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS86629.1 - 0.058 14.2 0.8 0.23 12.4 0.8 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ETS86629.1 - 0.43 10.4 3.6 0.28 11.0 0.8 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type LamB_YcsF PF03746.16 ETS86630.1 - 1.6e-80 270.2 0.0 1.9e-80 270.0 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family adh_short_C2 PF13561.6 ETS86631.1 - 1.5e-57 194.8 0.2 2.2e-57 194.3 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS86631.1 - 9.8e-41 139.4 0.0 1.3e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS86631.1 - 1.8e-07 31.2 0.1 2.2e-06 27.7 0.0 2.2 2 1 0 2 2 2 1 KR domain ThiF PF00899.21 ETS86631.1 - 0.0026 17.1 0.9 0.34 10.2 0.2 2.2 2 0 0 2 2 2 2 ThiF family Methyltransf_25 PF13649.6 ETS86631.1 - 0.041 14.6 0.0 0.13 13.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF5448 PF17526.2 ETS86631.1 - 0.072 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5448) Cyclase PF04199.13 ETS86632.1 - 1.9e-27 96.2 0.0 2.4e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase Gln-synt_C PF00120.24 ETS86634.1 - 6.9e-79 265.3 0.0 9.2e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Nt_Gln_amidase PF09764.9 ETS86634.1 - 0.0034 17.0 0.0 0.0073 15.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal glutamine amidase Aa_trans PF01490.18 ETS86636.1 - 6.8e-28 97.5 37.0 8.5e-28 97.2 37.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 ETS86636.1 - 6.8e-05 21.9 49.8 0.0072 15.2 49.9 2.1 1 1 0 1 1 1 1 Amino acid permease COX4 PF02936.14 ETS86636.1 - 6.5 6.8 5.7 2.9 7.9 0.1 2.8 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV Acetyltransf_1 PF00583.25 ETS86637.1 - 4.1e-10 39.9 0.0 5.8e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS86637.1 - 1.4e-06 28.6 0.0 2.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS86637.1 - 7.8e-06 25.8 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase PF00903.25 ETS86637.1 - 0.01 16.0 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FR47 PF08445.10 ETS86637.1 - 0.061 13.3 0.0 0.25 11.3 0.0 1.9 1 1 1 2 2 2 0 FR47-like protein AAA PF00004.29 ETS86639.1 - 4.6e-19 69.2 0.0 1.4e-17 64.4 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS86639.1 - 1.2e-05 25.7 0.8 0.0053 17.0 0.1 3.2 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 ETS86639.1 - 0.00026 21.4 0.8 0.0017 18.8 0.1 2.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 ETS86639.1 - 0.00047 20.2 0.0 0.0018 18.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ETS86639.1 - 0.001 18.9 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 ETS86639.1 - 0.019 15.0 0.1 0.2 11.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain Zot PF05707.12 ETS86639.1 - 0.022 14.4 0.2 0.17 11.5 0.0 2.5 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) TIP49 PF06068.13 ETS86639.1 - 0.035 13.3 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_2 PF07724.14 ETS86639.1 - 0.045 13.9 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 ETS86639.1 - 0.064 13.8 0.1 2.7 8.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 ETS86639.1 - 0.11 12.1 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain BAR PF03114.18 ETS86640.1 - 0.0092 15.6 0.4 0.015 15.0 0.4 1.3 1 0 0 1 1 1 1 BAR domain NACHT PF05729.12 ETS86640.1 - 0.049 13.6 0.1 0.21 11.5 0.0 2.1 3 0 0 3 3 3 0 NACHT domain Cupin_2 PF07883.11 ETS86641.1 - 8.4e-09 35.0 0.0 1.8e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 ETS86641.1 - 0.0017 18.0 0.1 0.0056 16.3 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 ETS86641.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Cupin FAD_binding_3 PF01494.19 ETS86642.1 - 4.9e-22 78.6 0.1 7.8e-22 78.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain ADC PF06314.11 ETS86642.1 - 1e-12 48.1 0.0 2.5e-12 46.9 0.0 1.6 2 0 0 2 2 2 1 Acetoacetate decarboxylase (ADC) Pyr_redox_2 PF07992.14 ETS86642.1 - 3.1e-07 29.9 3.2 1.6e-05 24.3 0.2 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS86642.1 - 8.5e-07 29.1 0.9 3.2e-06 27.3 0.5 2.2 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS86642.1 - 2.1e-05 24.3 0.3 0.00094 18.9 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS86642.1 - 4.8e-05 22.6 0.8 4.8e-05 22.6 0.8 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 ETS86642.1 - 0.0021 17.5 0.2 0.004 16.5 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ETS86642.1 - 0.0031 16.7 0.2 0.0052 15.9 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 ETS86642.1 - 0.0085 15.2 0.2 0.016 14.3 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 ETS86642.1 - 0.024 15.2 0.1 0.071 13.7 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS86642.1 - 0.033 13.4 0.1 0.17 11.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS86642.1 - 0.049 12.3 0.1 0.081 11.6 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein AlaDh_PNT_C PF01262.21 ETS86642.1 - 0.056 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ETS86642.1 - 0.074 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 ETS86642.1 - 0.084 11.7 0.1 0.3 9.9 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.24 ETS86642.1 - 0.11 11.7 0.6 1.6 7.9 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 ETS86642.1 - 5.3 7.0 7.0 1.1 9.2 1.8 2.3 2 1 0 2 2 2 0 FAD-NAD(P)-binding adh_short_C2 PF13561.6 ETS86643.1 - 1.6e-40 139.2 0.5 2.1e-40 138.7 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS86643.1 - 2.5e-36 125.0 0.0 3.3e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS86643.1 - 1.5e-09 38.1 0.1 2.3e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 ETS86644.1 - 6.9e-35 120.6 31.2 6.9e-35 120.6 31.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS86644.1 - 1.9e-10 40.2 21.8 1.9e-10 40.2 21.8 3.1 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ETS86644.1 - 0.0019 16.7 4.3 0.011 14.2 4.6 1.9 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 ETS86645.1 - 2.4e-14 53.0 0.2 6.1e-14 51.7 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 ETS86645.1 - 5.1e-12 45.6 4.5 2.4e-05 24.5 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 ETS86645.1 - 2.9e-05 24.1 10.5 2.9e-05 24.1 10.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 ETS86645.1 - 6.1e-05 23.5 12.2 0.021 15.6 0.9 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ETS86645.1 - 0.0012 19.2 0.5 0.0012 19.2 0.5 3.5 3 1 0 3 3 3 1 Zinc-finger double domain Spt46 PF17734.1 ETS86645.1 - 0.004 17.0 0.7 0.0099 15.7 0.7 1.6 1 0 0 1 1 1 1 Spermatogenesis-associated protein 46 zf-met PF12874.7 ETS86645.1 - 0.048 14.1 4.0 4.3 7.9 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF4107 PF13389.6 ETS86645.1 - 0.063 13.4 0.3 0.14 12.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) zf-C2H2_11 PF16622.5 ETS86645.1 - 0.079 12.7 5.0 2.1 8.2 1.5 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 ETS86645.1 - 1.5 9.2 4.9 5 7.5 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Hydrolase_4 PF12146.8 ETS86646.1 - 4.4e-13 49.1 0.0 6.5e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS86646.1 - 5.3e-11 42.6 0.2 1.2e-10 41.5 0.2 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS86646.1 - 8.9e-10 39.5 4.7 1.9e-09 38.5 4.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 ETS86646.1 - 0.0086 15.7 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 ETS86646.1 - 0.013 15.6 0.1 0.39 10.8 0.1 2.2 2 0 0 2 2 2 0 Thioesterase domain RtxA PF07634.11 ETS86646.1 - 0.072 13.6 0.1 0.25 11.9 0.1 2.0 1 0 0 1 1 1 0 RtxA repeat DLH PF01738.18 ETS86646.1 - 0.095 12.2 0.0 0.58 9.7 0.0 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family dCMP_cyt_deam_1 PF00383.23 ETS86648.1 - 3e-13 49.5 0.1 3.9e-13 49.1 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 ETS86648.1 - 6.1e-09 36.2 3.1 5.4e-08 33.1 0.3 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 ETS86648.1 - 0.0096 15.5 0.7 0.56 9.8 0.7 2.1 1 1 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases ELMO_CED12 PF04727.13 ETS86649.1 - 1.4e-50 171.8 0.3 3.4e-50 170.6 0.3 1.6 2 0 0 2 2 2 1 ELMO/CED-12 family PH_12 PF16457.5 ETS86649.1 - 5.3e-36 124.1 0.0 1e-35 123.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 ETS86649.1 - 1.2e-13 51.3 0.0 2.9e-13 50.0 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) zf-GRF PF06839.12 ETS86650.1 - 1.4e-06 28.3 4.8 3.1e-06 27.2 4.8 1.6 1 0 0 1 1 1 1 GRF zinc finger ORF6C PF10552.9 ETS86650.1 - 0.82 9.8 3.2 0.97 9.5 1.4 1.9 2 0 0 2 2 2 0 ORF6C domain GMC_oxred_N PF00732.19 ETS86651.1 - 3e-30 105.6 0.0 9.3e-29 100.7 0.0 2.7 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS86651.1 - 1.4e-27 97.0 0.0 2.4e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 ETS86651.1 - 2.4e-06 27.0 0.1 0.00039 19.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS86651.1 - 0.0011 19.1 0.1 0.0053 17.0 0.0 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS86651.1 - 0.013 14.7 0.0 1.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS86651.1 - 0.092 11.4 0.6 0.3 9.7 0.5 1.7 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 ETS86651.1 - 0.15 11.3 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS86651.1 - 0.26 10.3 2.4 0.5 9.4 1.7 1.7 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 ETS86652.1 - 4.4e-34 118.6 0.0 5.3e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS86652.1 - 1.7e-05 25.0 0.1 4.6e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS86652.1 - 0.00039 19.8 0.0 0.00097 18.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS86652.1 - 0.0009 18.4 0.0 0.0025 17.0 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 ETS86652.1 - 0.0019 17.5 0.0 0.0094 15.2 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 ETS86652.1 - 0.0023 17.9 0.1 0.015 15.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ETS86652.1 - 0.0048 16.2 0.0 0.032 13.5 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ETS86652.1 - 0.0051 16.9 0.0 0.0097 16.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 ETS86652.1 - 0.0069 15.7 0.0 0.021 14.1 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 ETS86652.1 - 0.026 14.0 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Trp_halogenase PF04820.14 ETS86652.1 - 0.033 13.0 0.0 0.91 8.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 ETS86652.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 ETS86652.1 - 0.073 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 ETS86652.1 - 0.11 12.1 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 ETS86652.1 - 0.11 13.0 0.0 0.37 11.4 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ETS86652.1 - 0.12 11.4 0.0 1.9 7.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.18 ETS86652.1 - 0.15 12.3 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Sugar_tr PF00083.24 ETS86653.1 - 2.3e-53 181.7 14.5 2.9e-53 181.3 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS86653.1 - 5.4e-17 61.8 34.0 3.5e-15 55.8 13.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS86654.1 - 1.7e-05 23.9 1.3 1.9e-05 23.7 1.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS86654.1 - 0.021 13.8 0.3 0.022 13.7 0.3 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Ribonuc_L-PSP PF01042.21 ETS86655.1 - 4.3e-17 62.2 0.0 4.6e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fungal_trans PF04082.18 ETS86656.1 - 4.6e-23 81.6 0.2 6.8e-23 81.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS86656.1 - 2.4e-10 40.3 7.9 6.6e-10 39.0 7.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.7 ETS86658.1 - 5.5e-05 23.7 0.1 0.02 15.5 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 ETS86658.1 - 0.0032 17.9 0.1 0.032 14.7 0.2 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 ETS86658.1 - 0.006 17.0 0.0 0.076 13.6 0.0 3.1 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 ETS86658.1 - 0.0099 16.2 0.0 0.034 14.5 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS86658.1 - 0.027 15.0 0.2 0.52 11.0 0.0 2.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Helo_like_N PF17111.5 ETS86658.1 - 0.053 12.9 0.0 0.71 9.2 0.0 2.6 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins peroxidase PF00141.23 ETS86659.1 - 1.2e-21 77.5 1.3 1.3e-21 77.4 0.2 1.6 2 0 0 2 2 2 1 Peroxidase PSI_PSAK PF01241.18 ETS86659.1 - 0.0097 15.9 0.1 0.021 14.8 0.1 1.6 1 0 0 1 1 1 1 Photosystem I psaG / psaK SGL PF08450.12 ETS86660.1 - 2.2e-08 34.0 0.1 4.5e-07 29.7 0.1 2.0 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region DUF839 PF05787.13 ETS86660.1 - 0.15 11.2 0.2 0.22 10.7 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) NHL PF01436.21 ETS86660.1 - 2.8 8.2 9.0 7.1 6.9 0.1 4.1 4 0 0 4 4 4 0 NHL repeat SnoaL_4 PF13577.6 ETS86661.1 - 2e-11 44.1 0.0 2.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain p450 PF00067.22 ETS86662.1 - 1e-30 106.9 0.0 1e-18 67.4 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 Fungal_trans PF04082.18 ETS86663.1 - 3.8e-12 45.8 0.2 5.8e-12 45.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_2 PF00891.18 ETS86664.1 - 1.8e-18 66.6 0.0 4.2e-18 65.4 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_25 PF13649.6 ETS86664.1 - 1.6e-05 25.5 0.0 5.4e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS86664.1 - 0.00069 19.4 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS86664.1 - 0.002 18.8 0.0 0.005 17.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS86664.1 - 0.0067 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain YcaO_C PF18381.1 ETS86664.1 - 0.015 15.2 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 YcaO cyclodehydratase C-terminal domain Ubie_methyltran PF01209.18 ETS86664.1 - 0.025 13.9 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Receptor_IA-2 PF11548.8 ETS86664.1 - 0.046 13.7 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein-tyrosine phosphatase receptor IA-2 HTH_24 PF13412.6 ETS86664.1 - 0.053 13.1 0.2 0.19 11.3 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Methyltransf_5 PF01795.19 ETS86664.1 - 0.067 12.7 0.0 9.3 5.6 0.0 2.1 2 0 0 2 2 2 0 MraW methylase family HTH_36 PF13730.6 ETS86664.1 - 0.13 12.2 0.0 0.43 10.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain PS-DH PF14765.6 ETS86665.1 - 6.9e-71 238.9 0.0 1.9e-70 237.5 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 ETS86665.1 - 1.1e-67 228.3 0.0 2.4e-67 227.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 ETS86665.1 - 2.2e-56 190.6 1.8 1.2e-55 188.2 0.1 2.7 2 1 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 ETS86665.1 - 7.7e-49 166.9 0.0 1.5e-48 166.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 ETS86665.1 - 5e-33 113.6 0.0 1.1e-32 112.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 ETS86665.1 - 6.7e-20 71.7 0.0 2.3e-18 66.7 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ETS86665.1 - 3.4e-17 62.9 0.2 1.4e-12 48.1 0.0 2.7 1 1 1 2 2 2 2 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 ETS86665.1 - 8.4e-12 45.6 0.1 5.3e-10 39.8 0.0 4.1 4 0 0 4 4 3 1 Methyltransferase domain adh_short PF00106.25 ETS86665.1 - 1.5e-11 44.1 0.6 9.2e-09 35.0 0.0 3.2 2 1 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.26 ETS86665.1 - 5.7e-11 42.5 0.0 1.2e-09 38.2 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 ETS86665.1 - 1.7e-10 41.5 0.0 1.5e-09 38.5 0.0 2.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS86665.1 - 5.6e-10 39.3 0.0 2.7e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 ETS86665.1 - 3.2e-09 37.0 0.1 8.7e-09 35.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 ETS86665.1 - 4.4e-09 37.5 0.0 1.1e-06 29.8 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 ETS86665.1 - 1.6e-08 34.5 0.0 1.2e-07 31.6 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain 3Beta_HSD PF01073.19 ETS86665.1 - 2.1e-05 23.7 0.0 3.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 ETS86665.1 - 2.5e-05 23.9 0.4 0.00013 21.6 0.1 2.4 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 ETS86665.1 - 0.00016 21.5 0.0 0.00038 20.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 ETS86665.1 - 0.00034 20.0 0.0 0.00075 18.9 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.15 ETS86665.1 - 0.00056 19.1 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Thiolase_N PF00108.23 ETS86665.1 - 0.00093 18.6 0.4 0.0038 16.6 0.4 2.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain Cadherin_2 PF08266.12 ETS86665.1 - 0.041 13.7 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Cadherin-like RNA_pol_Rpb8 PF03870.15 ETS86665.1 - 0.061 13.5 0.1 0.19 11.9 0.0 1.8 2 0 0 2 2 1 0 RNA polymerase Rpb8 ACP_syn_III PF08545.10 ETS86665.1 - 0.069 13.0 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_33 PF10017.9 ETS86665.1 - 0.096 11.8 0.0 0.26 10.4 0.0 1.7 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent GDP_Man_Dehyd PF16363.5 ETS86665.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_3 PF03447.16 ETS86665.1 - 0.22 12.2 0.8 1.8 9.2 0.0 2.9 4 0 0 4 4 2 0 Homoserine dehydrogenase, NAD binding domain FAD_binding_4 PF01565.23 ETS86666.1 - 1.7e-25 89.3 0.3 3.1e-25 88.5 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ETS86666.1 - 3.5e-05 23.8 0.1 9.8e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like MTABC_N PF16185.5 ETS86666.1 - 0.0099 15.4 0.0 0.024 14.1 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ABC-transporter N-terminal five TM region GMC_oxred_N PF00732.19 ETS86667.1 - 6.8e-48 163.5 0.1 9.1e-48 163.1 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS86667.1 - 3.2e-32 112.0 0.0 6.2e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ETS86667.1 - 2.7e-06 26.7 0.0 5.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 ETS86667.1 - 1.9e-05 24.5 0.0 0.11 12.1 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS86667.1 - 0.00032 19.9 0.2 0.39 9.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ETS86667.1 - 0.0012 19.0 0.1 0.006 16.8 0.1 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ETS86667.1 - 0.013 14.4 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 ETS86667.1 - 0.063 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS86667.1 - 0.071 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DUF3638 PF12340.8 ETS86668.1 - 7.3e-94 313.3 1.6 1.7e-93 312.1 0.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 ETS86668.1 - 3.2e-17 61.6 0.7 7e-17 60.5 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) HTH_36 PF13730.6 ETS86668.1 - 0.071 13.1 0.2 0.23 11.4 0.2 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain HSCB_C PF07743.13 ETS86669.1 - 4.6e-23 81.5 8.3 3.1e-22 78.8 6.9 2.3 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 ETS86669.1 - 0.00028 20.9 0.0 0.00069 19.7 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain ThiD2 PF17792.1 ETS86669.1 - 0.53 10.8 6.7 0.32 11.5 0.7 2.8 3 0 0 3 3 3 0 ThiD2 family MGC-24 PF05283.11 ETS86669.1 - 0.94 9.9 4.3 1.7 9.1 4.3 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin LRR_4 PF12799.7 ETS86670.1 - 0.0029 18.0 7.0 0.0067 16.8 0.9 3.9 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ETS86670.1 - 0.022 14.5 4.4 0.034 13.9 1.2 2.6 3 0 0 3 3 3 0 Leucine rich repeat SoxD PF04267.12 ETS86670.1 - 0.028 14.5 1.7 0.068 13.3 1.7 1.6 1 0 0 1 1 1 0 Sarcosine oxidase, delta subunit family Cwf_Cwc_15 PF04889.12 ETS86671.1 - 0.58 9.8 5.8 0.75 9.5 5.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PAN_1 PF00024.26 ETS86672.1 - 1.7e-05 24.7 0.1 3.3e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 ETS86672.1 - 2e-05 24.4 0.4 7.8e-05 22.5 0.4 2.1 1 1 0 1 1 1 1 PAN domain DDDD PF10161.9 ETS86672.1 - 0.22 11.3 0.2 0.72 9.6 0.0 1.9 2 0 0 2 2 2 0 Putative mitochondrial precursor protein MFS_1 PF07690.16 ETS86673.1 - 1.2e-33 116.5 34.9 1.2e-33 116.5 34.9 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily COX14 PF14880.6 ETS86673.1 - 1.8 8.5 4.4 92 3.0 3.7 2.8 2 0 0 2 2 2 0 Cytochrome oxidase c assembly BCS1_N PF08740.11 ETS86674.1 - 2.9e-42 144.8 0.1 3.8e-42 144.4 0.1 1.1 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 ETS86674.1 - 3.7e-18 66.2 0.0 6.1e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS86674.1 - 0.00033 21.1 0.0 0.0011 19.3 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 ETS86674.1 - 0.001 18.9 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 ETS86674.1 - 0.0025 17.4 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 ETS86674.1 - 0.0044 17.2 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ETS86674.1 - 0.0052 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 ETS86674.1 - 0.007 15.6 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 ETS86674.1 - 0.0076 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ETS86674.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ETS86674.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ETS86674.1 - 0.014 15.9 0.0 0.033 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 ETS86674.1 - 0.036 14.6 0.0 0.069 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ETS86674.1 - 0.045 14.1 0.0 0.14 12.5 0.0 1.9 2 0 0 2 2 1 0 RNA helicase PPV_E1_C PF00519.17 ETS86674.1 - 0.049 12.5 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase AAA_11 PF13086.6 ETS86674.1 - 0.049 13.4 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ETS86674.1 - 0.061 13.4 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Rad17 PF03215.15 ETS86674.1 - 0.065 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Viral_helicase1 PF01443.18 ETS86674.1 - 0.074 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 ETS86674.1 - 0.085 12.8 0.0 0.44 10.4 0.0 2.1 3 0 0 3 3 2 0 NACHT domain ATP_bind_1 PF03029.17 ETS86674.1 - 0.099 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ATPase PF06745.13 ETS86674.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 ETS86674.1 - 0.15 12.0 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Iso_dh PF00180.20 ETS86675.1 - 8.1e-81 271.9 0.0 9.1e-81 271.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AMP-binding PF00501.28 ETS86676.1 - 5.1e-82 275.7 0.0 6.5e-82 275.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS86676.1 - 1.1e-14 55.2 0.1 2.5e-14 54.0 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_hydro_7 PF00840.20 ETS86677.1 - 3.9e-198 658.6 20.4 4.4e-198 658.4 20.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF3086 PF11285.8 ETS86678.1 - 0.00069 18.8 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3086) TPR_9 PF13371.6 ETS86678.1 - 0.0034 17.5 0.1 0.013 15.6 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat MFS_1 PF07690.16 ETS86679.1 - 8.1e-39 133.5 39.0 5.4e-38 130.8 22.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 ETS86679.1 - 1.8e-08 33.8 0.4 7.6e-06 25.1 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS86679.1 - 3.6e-06 27.0 10.2 6.8e-06 26.1 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_16 PF00722.21 ETS86680.1 - 2.2e-15 56.6 0.2 9.6e-15 54.5 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 ETS86680.1 - 0.0033 15.9 3.6 0.12 10.8 0.4 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Peptidase_M20 PF01546.28 ETS86681.1 - 2.4e-06 27.4 1.7 4.4e-06 26.5 1.7 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ETS86681.1 - 0.00014 21.7 0.1 0.00029 20.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.16 ETS86682.1 - 1.8e-34 119.2 27.9 2.6e-34 118.7 27.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CDH-cyt PF16010.5 ETS86683.1 - 1.1e-23 83.8 5.4 2.1e-23 83.0 5.4 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 ETS86683.1 - 2.7e-08 34.1 0.6 3.7e-07 30.4 0.2 2.5 2 0 0 2 2 2 1 DOMON domain DUF2427 PF10348.9 ETS86683.1 - 7.7e-06 25.7 8.7 7.7e-06 25.7 8.7 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 ETS86683.1 - 9.3e-06 25.8 14.7 2.9e-05 24.2 14.7 1.8 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 RAP1 PF07218.11 ETS86683.1 - 8.3 4.6 17.3 11 4.1 17.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.25 ETS86684.1 - 8.2e-68 228.6 0.0 1e-67 228.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS86684.1 - 6.7e-31 107.5 0.0 9e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ETS86684.1 - 0.0041 15.9 0.0 0.0091 14.8 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Pkinase_C PF00433.24 ETS86684.1 - 0.0076 16.9 0.1 0.036 14.8 0.2 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 ETS86684.1 - 0.037 13.0 0.1 0.057 12.4 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 ETS86684.1 - 0.061 12.9 0.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 ETS86684.1 - 0.13 11.6 0.1 0.23 10.7 0.0 1.6 1 1 0 1 1 1 0 Kinase-like PH PF00169.29 ETS86685.1 - 2e-07 31.5 0.1 2.8e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 ETS86685.1 - 0.022 15.1 0.0 0.055 13.8 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PP2C_2 PF13672.6 ETS86686.1 - 0.00088 19.0 0.0 0.0015 18.2 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 ETS86686.1 - 0.0028 17.6 0.0 0.017 15.1 0.0 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Fcf1 PF04900.12 ETS86687.1 - 2.2e-30 105.0 0.0 4.6e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 Fcf1 CDC45 PF02724.14 ETS86687.1 - 5.9 5.1 15.3 8.6 4.5 15.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF726 PF05277.12 ETS86688.1 - 1.1e-128 429.1 2.2 1.4e-128 428.6 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) SKG6 PF08693.10 ETS86689.1 - 5.6e-05 22.5 1.5 5.6e-05 22.5 1.5 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain VSP PF03302.13 ETS86689.1 - 0.0059 15.5 5.5 0.0099 14.8 5.5 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein AJAP1_PANP_C PF15298.6 ETS86689.1 - 0.0097 16.1 1.5 0.0097 16.1 1.5 2.1 2 0 0 2 2 2 1 AJAP1/PANP C-terminus Rax2 PF12768.7 ETS86689.1 - 0.054 13.0 0.6 0.094 12.2 0.0 1.6 2 0 0 2 2 2 0 Cortical protein marker for cell polarity DAG1 PF05454.11 ETS86689.1 - 0.18 11.2 0.0 1 8.7 0.0 2.0 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) MGC-24 PF05283.11 ETS86689.1 - 1.3 9.5 9.6 0.29 11.6 5.2 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF846 PF05832.12 ETS86690.1 - 2e-52 176.9 8.0 2.4e-52 176.7 8.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4191 PF13829.6 ETS86690.1 - 0.94 8.8 4.4 3.5 6.9 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DuoxA PF10204.9 ETS86690.1 - 3.1 6.7 12.9 1.1 8.3 3.7 2.1 1 1 1 2 2 2 0 Dual oxidase maturation factor Cu2_monoox_C PF03712.15 ETS86691.1 - 0.0075 15.8 0.0 0.0099 15.4 0.0 1.1 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Selenoprotein_S PF06936.11 ETS86693.1 - 0.00074 19.4 0.6 0.00083 19.2 0.6 1.0 1 0 0 1 1 1 1 Selenoprotein S (SelS) Cortex-I_coil PF09304.10 ETS86693.1 - 0.0022 18.2 1.5 0.0026 17.9 1.5 1.1 1 0 0 1 1 1 1 Cortexillin I, coiled coil MIS13 PF08202.11 ETS86693.1 - 0.0086 15.4 0.6 0.0087 15.4 0.6 1.0 1 0 0 1 1 1 1 Mis12-Mtw1 protein family DUF2730 PF10805.8 ETS86693.1 - 0.0089 16.1 0.6 0.0089 16.1 0.6 2.4 1 1 2 3 3 3 1 Protein of unknown function (DUF2730) SKA2 PF16740.5 ETS86693.1 - 0.018 14.8 0.8 0.021 14.6 0.8 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 NPV_P10 PF05531.12 ETS86693.1 - 0.048 14.1 0.7 0.065 13.7 0.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein YedD PF13987.6 ETS86693.1 - 0.058 13.2 0.1 0.064 13.1 0.1 1.1 1 0 0 1 1 1 0 YedD-like protein p450 PF00067.22 ETS86694.1 - 1.1e-47 162.9 0.0 1.3e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ATPase PF06745.13 ETS86694.1 - 0.098 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiC NAD_binding_10 PF13460.6 ETS86695.1 - 3.3e-11 43.4 0.0 3.2e-10 40.2 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ETS86695.1 - 2.5e-10 40.3 0.0 3.1e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 ETS86695.1 - 0.0011 19.3 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ETS86695.1 - 0.0011 19.2 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.10 ETS86695.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.20 ETS86695.1 - 0.02 15.0 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Gp_dh_N PF00044.24 ETS86695.1 - 0.031 14.6 0.0 0.11 12.8 0.0 1.9 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 ETS86695.1 - 0.033 14.3 0.0 0.06 13.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PglD_N PF17836.1 ETS86695.1 - 0.049 14.3 0.0 0.1 13.3 0.0 1.6 1 1 0 1 1 1 0 PglD N-terminal domain ApbA PF02558.16 ETS86695.1 - 0.057 13.1 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 ETS86695.1 - 0.063 13.7 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 3Beta_HSD PF01073.19 ETS86695.1 - 0.072 12.1 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.19 ETS86695.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IU_nuc_hydro PF01156.19 ETS86697.1 - 2.5e-53 181.6 0.0 4.2e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase LSM PF01423.22 ETS86698.1 - 6.2e-16 57.8 0.2 8.7e-16 57.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain Alpha-amylase PF00128.24 ETS86700.1 - 1.1e-58 199.4 0.9 1.7e-58 198.8 0.9 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.19 ETS86700.1 - 8.7e-33 112.1 0.6 2.6e-32 110.6 0.6 1.9 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.11 ETS86700.1 - 2e-09 37.6 0.1 8.1e-09 35.6 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DUF3499 PF12005.8 ETS86700.1 - 0.046 14.3 0.2 2.9 8.5 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) Fungal_trans PF04082.18 ETS86701.1 - 5.7e-14 51.8 0.3 1e-13 50.9 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS86701.1 - 2.1e-07 30.9 9.4 3.4e-07 30.3 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AviRa PF11599.8 ETS86701.1 - 0.17 11.3 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Cu-oxidase_3 PF07732.15 ETS86702.1 - 4.8e-43 146.0 1.8 4.8e-43 146.0 1.8 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ETS86702.1 - 3.3e-37 127.3 6.0 2.5e-35 121.2 0.4 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 ETS86702.1 - 6.3e-26 91.4 0.0 7.6e-25 87.9 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Glutaredoxin PF00462.24 ETS86703.1 - 1.1e-17 64.0 0.0 1.9e-16 60.0 0.0 2.5 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 ETS86703.1 - 2.8e-12 46.5 0.0 6.3e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ETS86703.1 - 0.028 14.8 0.1 0.48 10.9 0.0 2.7 2 2 1 3 3 3 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ETS86703.1 - 0.17 12.2 0.0 24 5.3 0.0 2.7 1 1 2 3 3 3 0 Thioredoxin-like HET PF06985.11 ETS86704.1 - 1.6e-35 122.6 0.1 3.6e-35 121.4 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 ETS86705.1 - 2.6e-35 121.9 0.5 4.8e-35 121.1 0.5 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans_2 PF11951.8 ETS86706.1 - 0.093 11.5 0.0 0.75 8.5 0.0 1.9 2 0 0 2 2 2 0 Fungal specific transcription factor domain SH3_9 PF14604.6 ETS86708.1 - 3.3e-27 94.1 11.0 3.5e-14 52.4 0.4 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 ETS86708.1 - 5e-25 86.9 3.6 1e-12 47.4 0.5 2.6 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 ETS86708.1 - 5.2e-16 58.5 0.0 9.3e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 ETS86708.1 - 1.3e-15 56.7 0.0 1.5e-06 27.7 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain zf-H2C2_2 PF13465.6 ETS86709.1 - 1.7e-06 28.2 9.0 3.6e-06 27.2 1.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ETS86709.1 - 2.4e-05 24.2 0.5 0.066 13.2 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ETS86709.1 - 2.7e-05 24.4 0.3 2.7e-05 24.4 0.3 3.5 3 1 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 ETS86709.1 - 3.2e-05 24.5 4.8 0.16 12.6 0.0 3.8 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 ETS86709.1 - 0.00038 21.1 3.7 0.013 16.3 0.3 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger CagY_I PF14585.6 ETS86709.1 - 0.078 13.1 2.6 0.18 11.9 0.4 2.5 2 0 0 2 2 2 0 CagY type 1 repeat Sina PF03145.16 ETS86709.1 - 0.14 12.1 7.6 3.7 7.4 2.5 2.7 1 1 1 2 2 2 0 Seven in absentia protein family zf-C2H2_11 PF16622.5 ETS86709.1 - 0.2 11.4 0.3 0.57 10.0 0.0 1.9 2 0 0 2 2 2 0 zinc-finger C2H2-type Fe_hyd_lg_C PF02906.14 ETS86711.1 - 4.6e-53 180.4 0.0 9.7e-53 179.3 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SUZ PF12752.7 ETS86712.1 - 0.0037 18.0 3.7 0.0037 18.0 3.7 3.8 2 1 1 3 3 3 1 SUZ domain eIF3_subunit PF08597.10 ETS86712.1 - 9.2 6.1 13.9 19 5.0 0.4 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Pkinase PF00069.25 ETS86715.1 - 7.4e-68 228.8 0.0 9.8e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS86715.1 - 1.1e-30 106.8 0.0 1.6e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ETS86715.1 - 1.8e-12 47.7 3.4 5.2e-12 46.3 1.6 2.8 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 ETS86715.1 - 2.7e-10 40.5 0.0 7.1e-07 29.5 0.0 2.6 2 0 0 2 2 2 2 C2 domain Kinase-like PF14531.6 ETS86715.1 - 4.9e-10 39.2 0.1 2e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ETS86715.1 - 0.00046 19.3 0.0 0.00088 18.3 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ETS86715.1 - 0.024 14.0 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 ETS86715.1 - 0.099 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 ETS86715.1 - 0.12 12.0 0.2 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 HET PF06985.11 ETS86716.1 - 2.6e-06 27.9 0.0 3.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ATP_sub_h PF10775.9 ETS86717.1 - 1.3e-26 92.4 0.5 2.1e-26 91.7 0.5 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.11 ETS86717.1 - 0.094 13.1 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Lipase_GDSL_2 PF13472.6 ETS86719.1 - 2.2e-18 67.3 0.0 2.7e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS86719.1 - 7.5e-08 32.6 0.0 1.7e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PCI PF01399.27 ETS86720.1 - 1.7e-12 47.7 0.0 2.4e-11 44.1 0.0 2.6 2 1 0 2 2 2 1 PCI domain RPN7 PF10602.9 ETS86720.1 - 0.00011 22.0 0.2 0.00023 20.9 0.2 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 FAD-SLDH PF12318.8 ETS86720.1 - 0.11 12.5 0.1 0.31 11.1 0.1 1.8 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase PVL_ORF50 PF07768.11 ETS86721.1 - 0.048 14.0 3.0 0.12 12.7 1.3 2.4 3 0 0 3 3 3 0 PVL ORF-50-like family peroxidase PF00141.23 ETS86722.1 - 2e-48 165.1 0.0 2.9e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase CPSase_L_D2 PF02786.17 ETS86723.1 - 3.9e-109 363.1 0.0 2.1e-84 282.3 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 ETS86723.1 - 3.3e-40 137.2 0.0 7.9e-40 136.0 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 ETS86723.1 - 2.3e-20 72.9 0.3 1.8e-09 37.4 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ETS86723.1 - 1.3e-18 67.3 0.3 5.1e-08 32.7 0.1 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 ETS86723.1 - 9.5e-12 44.8 0.0 8e-05 22.4 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 ETS86723.1 - 7.7e-06 26.0 0.1 0.16 12.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 ETS86723.1 - 1.5e-05 24.9 1.4 0.093 12.5 0.1 3.0 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 ETS86723.1 - 0.00015 21.4 0.0 0.063 12.9 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 ETS86723.1 - 0.00031 20.3 0.9 0.14 11.6 0.1 3.2 3 1 1 4 4 4 2 ATP-grasp domain Tax PF02959.16 ETS86723.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 HTLV Tax Aldo_ket_red PF00248.21 ETS86724.1 - 2.9e-41 141.6 0.0 3.2e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Amidase PF01425.21 ETS86725.1 - 7.7e-57 193.2 0.3 1.6e-49 169.1 0.1 2.2 2 0 0 2 2 2 2 Amidase PHINT_rpt PF14882.6 ETS86725.1 - 0.085 13.1 0.0 32 4.9 0.0 2.9 2 0 0 2 2 2 0 Phage-integrase repeat unit Fungal_trans_2 PF11951.8 ETS86726.1 - 1e-43 149.7 0.0 1.2e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS86726.1 - 1.5e-06 28.2 9.4 1.5e-06 28.2 9.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_A21 PF03566.13 ETS86726.1 - 0.052 11.8 0.5 0.071 11.4 0.5 1.1 1 0 0 1 1 1 0 Peptidase family A21 CorA PF01544.18 ETS86727.1 - 3.5e-11 43.0 0.1 3.5e-11 43.0 0.1 2.4 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein DUF641 PF04859.12 ETS86727.1 - 0.38 11.1 4.3 0.55 10.6 0.2 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) p450 PF00067.22 ETS86728.1 - 3.6e-48 164.5 0.0 5e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_1 PF00232.18 ETS86728.1 - 0.043 12.2 0.0 0.089 11.2 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 1 MFS_1 PF07690.16 ETS86729.1 - 7.4e-37 127.1 42.1 7.4e-37 127.1 42.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ETS86729.1 - 1.2e-09 37.1 13.7 1.8e-09 36.6 13.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ETS86729.1 - 0.00073 18.5 22.0 0.0036 16.2 13.9 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter TatC PF00902.18 ETS86729.1 - 0.11 12.3 8.3 2.6 7.8 2.5 2.7 2 1 0 2 2 2 0 Sec-independent protein translocase protein (TatC) THOC2_N PF16134.5 ETS86729.1 - 0.24 10.0 0.1 0.35 9.4 0.1 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus ATPgrasp_N PF18130.1 ETS86731.1 - 1e-14 54.8 0.0 2.8e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 ETS86731.1 - 6e-08 32.4 0.0 1.9e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ETS86731.1 - 5.2e-05 22.9 0.0 0.00019 21.0 0.0 1.9 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 ETS86731.1 - 7.6e-05 22.8 0.0 0.00026 21.1 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 ETS86731.1 - 0.026 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain GSH-S_ATP PF02955.16 ETS86731.1 - 0.099 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain GARS_A PF01071.19 ETS86731.1 - 0.22 11.2 0.0 0.36 10.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain FAD_binding_4 PF01565.23 ETS86733.1 - 3.7e-20 72.1 5.8 3.7e-20 72.1 5.8 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 ETS86733.1 - 8.8e-13 48.1 0.1 1.9e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Ank_5 PF13857.6 ETS86734.1 - 6.1e-13 48.7 0.0 1.8e-05 24.9 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS86734.1 - 9.1e-13 48.6 0.0 1.8e-07 31.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS86734.1 - 7.9e-11 42.3 0.0 0.00036 21.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS86734.1 - 2e-07 31.2 0.0 0.0036 17.7 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 ETS86734.1 - 2.4e-07 30.5 0.0 0.034 14.7 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat zf-Di19 PF05605.12 ETS86734.1 - 0.16 12.3 1.4 30 5.0 0.0 3.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding T2SSF PF00482.23 ETS86734.1 - 0.55 10.2 2.3 15 5.5 0.2 2.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F zf-C2H2_4 PF13894.6 ETS86734.1 - 1.1 10.3 4.2 3.8e+02 2.4 0.0 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger HET PF06985.11 ETS86735.1 - 1.9e-11 44.5 11.4 3e-07 30.9 11.4 2.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 ETS86737.1 - 0.00043 20.8 0.3 0.0078 16.8 0.0 2.9 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS86737.1 - 0.0045 17.3 0.0 0.029 14.7 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Helo_like_N PF17111.5 ETS86737.1 - 0.0072 15.7 1.8 0.0098 15.3 0.5 1.7 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank PF00023.30 ETS86737.1 - 0.025 15.0 0.0 0.099 13.1 0.0 2.2 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.6 ETS86737.1 - 0.13 12.9 0.2 5.3 7.7 0.0 3.7 3 1 1 4 4 4 0 Ankyrin repeats (many copies) DUF1664 PF07889.12 ETS86737.1 - 0.21 11.6 2.2 0.66 10.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 ETS86737.1 - 2.1 7.1 8.2 2.2 7.1 6.4 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein NPL4 PF05021.15 ETS86739.1 - 5.1e-131 436.6 0.0 6.7e-131 436.2 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 ETS86739.1 - 2e-65 219.4 0.0 3.6e-65 218.5 0.0 1.5 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 ETS86739.1 - 3.7e-05 24.1 0.0 0.00016 22.1 0.0 2.0 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 PWWP PF00855.17 ETS86740.1 - 2.6e-14 53.4 0.3 2.2e-13 50.4 0.3 2.8 1 1 0 1 1 1 1 PWWP domain Sec63 PF02889.16 ETS86741.1 - 5.1e-164 543.6 1.0 1.4e-92 309.5 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 ETS86741.1 - 1.1e-46 158.8 0.0 1.8e-27 96.3 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 ETS86741.1 - 5.1e-32 110.4 1.0 5.1e-32 110.4 1.0 2.1 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 ETS86741.1 - 3.5e-23 82.5 0.0 1.2e-13 51.5 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ETS86741.1 - 3.5e-10 40.2 0.0 5.7e-08 33.1 0.0 3.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 ETS86741.1 - 3e-06 27.6 0.1 0.038 14.3 0.1 3.3 2 1 0 2 2 2 2 AAA domain PhoH PF02562.16 ETS86741.1 - 0.00046 19.7 0.0 0.05 13.1 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 ETS86741.1 - 0.002 17.3 0.0 0.63 9.1 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein TFIIE_alpha PF02002.17 ETS86741.1 - 0.029 14.2 2.0 13 5.7 0.1 3.6 4 0 0 4 4 4 0 TFIIE alpha subunit UvrD-helicase PF00580.21 ETS86741.1 - 0.058 12.9 0.4 2.5 7.5 0.0 2.9 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Rep_fac_C PF08542.11 ETS86743.1 - 7.1e-21 74.4 0.1 1.6e-20 73.3 0.1 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 ETS86743.1 - 4.5e-16 59.5 0.1 2.3e-15 57.2 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 ETS86743.1 - 1.4e-13 51.0 0.1 4.4e-08 33.1 0.0 3.1 3 0 0 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.15 ETS86743.1 - 1.3e-09 38.3 0.1 3.8e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 ETS86743.1 - 1.6e-06 28.0 0.1 1.6e-05 24.7 0.0 2.5 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ETS86743.1 - 1.5e-05 25.3 0.2 0.0015 18.8 0.0 3.0 2 2 0 2 2 2 1 AAA domain AAA_11 PF13086.6 ETS86743.1 - 2.8e-05 24.0 0.1 9.6e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS86743.1 - 3.4e-05 24.3 0.1 0.00095 19.6 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_assoc_2 PF16193.5 ETS86743.1 - 7.3e-05 23.0 0.1 0.00021 21.5 0.1 1.9 1 0 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 ETS86743.1 - 0.00018 21.3 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 ETS86743.1 - 0.00022 20.7 0.0 0.0091 15.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 ETS86743.1 - 0.0009 19.0 0.2 0.017 14.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 ETS86743.1 - 0.0012 18.9 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ETS86743.1 - 0.0013 19.0 0.0 0.014 15.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ETS86743.1 - 0.0032 17.0 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 ETS86743.1 - 0.0036 16.5 0.0 0.0059 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 ETS86743.1 - 0.01 15.5 0.0 0.083 12.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ETS86743.1 - 0.014 15.3 0.2 0.13 12.2 0.1 2.5 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 ETS86743.1 - 0.025 14.9 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF5338 PF17273.2 ETS86743.1 - 0.029 14.4 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5338) ResIII PF04851.15 ETS86743.1 - 0.03 14.3 0.0 0.21 11.6 0.0 2.2 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 ETS86743.1 - 0.04 13.1 0.0 0.1 11.8 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 ETS86743.1 - 0.044 14.3 0.0 0.12 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 ETS86743.1 - 0.071 13.0 0.0 0.34 10.8 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ETS86743.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 ETS86743.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 ETS86743.1 - 0.19 11.5 1.2 1.9 8.3 0.0 2.7 2 2 0 4 4 4 0 DEAD/DEAH box helicase DUF2417 PF10329.9 ETS86744.1 - 1.7e-82 276.4 5.7 2.3e-82 276.0 5.7 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_1 PF00561.20 ETS86744.1 - 0.00017 21.3 0.1 0.00029 20.6 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold GWT1 PF06423.12 ETS86744.1 - 2.2 8.4 9.5 19 5.4 0.1 2.6 2 1 1 3 3 3 0 GWT1 COesterase PF00135.28 ETS86746.1 - 2.7e-90 303.7 0.0 3.8e-77 260.3 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS86746.1 - 2.3e-08 34.2 0.0 5e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS86746.1 - 0.13 11.8 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family UQ_con PF00179.26 ETS86748.1 - 1.9e-41 141.0 0.0 4.4e-30 104.2 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.22 ETS86748.1 - 0.016 15.5 0.0 3.8 7.8 0.0 2.7 2 1 0 2 2 2 0 RWD domain UEV PF05743.13 ETS86748.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 UEV domain 3Beta_HSD PF01073.19 ETS86749.1 - 2.6e-62 210.4 0.0 3.3e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ETS86749.1 - 1.7e-29 103.0 0.2 2.5e-29 102.4 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS86749.1 - 1.5e-15 57.5 0.0 1.7e-14 54.0 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ETS86749.1 - 1.6e-11 43.8 0.2 2.1e-11 43.4 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ETS86749.1 - 2.5e-11 43.3 0.4 1.5e-08 34.1 0.3 2.2 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 ETS86749.1 - 2.1e-10 40.8 0.2 3e-10 40.3 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ETS86749.1 - 6.8e-07 28.7 0.0 3.5e-06 26.4 0.1 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ETS86749.1 - 6.3e-05 22.6 0.1 0.00011 21.9 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 ETS86749.1 - 0.00057 19.8 1.7 0.003 17.5 1.7 2.1 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.18 ETS86749.1 - 0.0019 18.4 0.1 0.013 15.8 0.1 2.1 1 1 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 ETS86749.1 - 0.0053 16.1 0.1 0.0076 15.6 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain RNA_pol_Rpb4 PF03874.16 ETS86750.1 - 5.7e-26 91.3 3.7 8.4e-26 90.7 3.7 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Sybindin PF04099.12 ETS86751.1 - 1.2e-51 174.4 0.0 1.6e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 ETS86751.1 - 9.3e-10 38.7 0.1 1.4e-09 38.2 0.1 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region VWA_2 PF13519.6 ETS86752.1 - 3.7e-24 85.4 0.9 6.7e-24 84.6 0.0 1.9 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 ETS86752.1 - 1.8e-10 41.3 0.2 2.6e-10 40.8 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 ETS86752.1 - 3.4e-08 33.5 0.0 5.3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 ETS86752.1 - 0.0063 16.4 1.8 0.017 15.0 1.8 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.9 ETS86753.1 - 1.2e-20 72.9 5.9 1.9e-20 72.2 5.9 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal SUI1 PF01253.22 ETS86754.1 - 1.1e-25 90.0 0.4 1.1e-25 90.0 0.4 1.8 2 0 0 2 2 2 1 Translation initiation factor SUI1 Img2 PF05046.14 ETS86754.1 - 0.007 16.6 0.1 0.014 15.7 0.1 1.6 1 1 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) TnpV PF14198.6 ETS86754.1 - 0.067 13.2 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 Transposon-encoded protein TnpV MscS_TM PF12794.7 ETS86754.1 - 0.11 11.3 3.0 0.15 10.9 3.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 RhoGAP PF00620.27 ETS86755.1 - 5.6e-39 133.4 0.0 1e-38 132.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 ETS86755.1 - 3.5e-29 100.8 44.1 6.7e-12 45.4 4.4 5.4 6 0 0 6 6 6 4 LIM domain zf_C2H2_13 PF18508.1 ETS86755.1 - 0.39 10.3 0.0 0.39 10.3 0.0 3.5 4 0 0 4 4 4 0 Zinc finger domain SKG6 PF08693.10 ETS86756.1 - 0.012 15.0 0.5 0.022 14.2 0.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 ETS86756.1 - 0.11 12.5 1.2 0.22 11.5 1.2 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF4690 PF15756.5 ETS86756.1 - 1.6 9.4 11.7 0.38 11.4 5.9 2.7 2 1 1 3 3 3 0 Small Novel Rich in Cartilage CPL PF08144.11 ETS86757.1 - 4.8e-35 121.0 0.0 2.6e-33 115.4 0.0 3.5 3 1 0 3 3 3 1 CPL (NUC119) domain DUF4065 PF13274.6 ETS86757.1 - 0.043 14.7 0.3 0.36 11.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) TraH_2 PF06871.11 ETS86757.1 - 0.36 10.4 5.7 0.074 12.7 0.3 2.4 2 1 1 3 3 3 0 TraH_2 RWD PF05773.22 ETS86758.1 - 2.7e-24 85.7 1.4 4.2e-24 85.1 1.4 1.3 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 ETS86758.1 - 1.7e-05 25.2 6.2 4.2e-05 24.0 6.2 1.7 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 HrpE PF06188.12 ETS86758.1 - 0.048 13.5 1.2 0.07 13.0 1.2 1.3 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF2852 PF11014.8 ETS86758.1 - 0.12 12.6 3.8 0.18 12.0 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) TPR_12 PF13424.6 ETS86759.1 - 1.5e-13 50.8 3.2 3.6e-07 30.4 0.1 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ETS86759.1 - 2.5e-13 50.4 4.1 9.6e-07 29.4 0.8 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ETS86759.1 - 1e-11 44.0 2.0 0.00047 20.1 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS86759.1 - 1.6e-09 38.2 6.1 0.0075 16.8 0.9 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 ETS86759.1 - 4.3e-09 35.9 0.1 0.00014 21.8 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 ETS86759.1 - 6.5e-06 26.5 9.1 0.85 10.6 0.1 5.0 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 ETS86759.1 - 2.5e-05 24.0 8.1 0.064 13.1 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 ETS86759.1 - 5.8e-05 23.2 0.0 3.7 8.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS86759.1 - 0.00012 21.5 8.6 0.0065 15.9 1.1 2.6 1 1 1 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 ETS86759.1 - 0.00019 21.2 1.0 0.024 14.6 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ETS86759.1 - 0.00022 20.9 0.3 0.014 15.2 0.0 3.5 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS86759.1 - 0.001 19.2 0.0 6.1 7.2 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ETS86759.1 - 0.0023 18.5 1.4 18 6.3 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Ribonuclease_3 PF00636.26 ETS86759.1 - 0.095 13.3 0.0 0.41 11.3 0.0 2.0 1 1 0 1 1 1 0 Ribonuclease III domain NOA36 PF06524.12 ETS86759.1 - 1.8 7.8 8.6 3.8 6.7 8.6 1.6 1 0 0 1 1 1 0 NOA36 protein TPR_20 PF14561.6 ETS86759.1 - 3 8.2 11.5 6.7 7.1 0.1 4.1 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 ETS86759.1 - 3.5 7.9 10.5 20 5.4 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 ETS86759.1 - 4 8.3 8.9 36 5.4 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat PsbT PF01405.17 ETS86761.1 - 1.2 9.0 4.0 2.1 8.2 4.0 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre T protein Rad51 PF08423.11 ETS86762.1 - 3.3e-127 423.0 0.0 4.2e-127 422.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 ETS86762.1 - 1.6e-09 37.6 0.0 2.5e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 ETS86762.1 - 3.6e-08 33.2 0.0 5e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 ETS86762.1 - 5e-05 22.8 0.2 0.00014 21.3 0.2 1.8 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 ETS86762.1 - 0.00011 22.7 1.0 0.00023 21.7 0.2 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain DnaB_C PF03796.15 ETS86762.1 - 0.0089 15.4 0.1 0.057 12.7 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 ETS86762.1 - 0.067 12.9 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ETS86762.1 - 0.097 12.9 0.1 0.35 11.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 ETS86762.1 - 0.12 12.4 0.2 0.6 10.1 0.1 2.0 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain Nup160 PF11715.8 ETS86763.1 - 6.8e-132 440.8 0.0 1e-131 440.2 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Vps26 PF03643.15 ETS86764.1 - 1.2e-130 434.5 0.6 1.4e-130 434.3 0.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 ETS86764.1 - 0.00055 20.0 0.9 1.1 9.3 0.0 3.5 1 1 2 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ETS86764.1 - 0.04 14.4 0.0 0.55 10.7 0.0 2.4 1 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain IL17R_D_N PF16742.5 ETS86764.1 - 0.066 13.3 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Ribosomal_L6 PF00347.23 ETS86765.1 - 4e-27 94.7 5.2 3.3e-13 50.1 0.8 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Glycophorin_A PF01102.18 ETS86766.1 - 0.028 14.7 0.2 0.028 14.7 0.2 2.3 2 0 0 2 2 2 0 Glycophorin A V-ATPase_H_N PF03224.14 ETS86767.1 - 2.3e-81 273.5 0.0 3e-81 273.2 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 ETS86767.1 - 1.2e-34 118.9 0.0 6.5e-34 116.6 0.0 2.2 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.6 ETS86767.1 - 0.0068 16.8 0.1 0.15 12.4 0.0 3.1 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.22 ETS86767.1 - 0.026 14.8 0.0 0.42 11.0 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat RIX1 PF08167.12 ETS86767.1 - 0.19 11.5 6.1 3.5 7.3 0.0 4.2 3 2 2 5 5 5 0 rRNA processing/ribosome biogenesis Aldedh PF00171.22 ETS86768.1 - 8.2e-133 443.3 0.1 8.2e-133 443.3 0.1 1.6 2 0 0 2 2 2 1 Aldehyde dehydrogenase family FmdE PF02663.14 ETS86768.1 - 0.098 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon F-box PF00646.33 ETS86769.1 - 5.3e-06 26.2 0.1 1.2e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ETS86769.1 - 2.7e-05 24.0 0.6 5.6e-05 22.9 0.6 1.6 1 0 0 1 1 1 1 F-box-like His_Phos_2 PF00328.22 ETS86770.1 - 4.4e-12 46.0 0.6 6.1e-08 32.4 0.1 3.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) TetR_C_14 PF17754.1 ETS86771.1 - 0.073 13.0 2.1 0.096 12.6 2.1 1.2 1 0 0 1 1 1 0 MftR C-terminal domain Peptidase_C12 PF01088.21 ETS86772.1 - 2.4e-42 145.1 0.0 2.8e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 MFS_1 PF07690.16 ETS86773.1 - 1.7e-28 99.6 37.2 3e-28 98.7 37.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS86773.1 - 1.9e-08 33.6 13.2 1.9e-08 33.6 13.2 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter PTR2 PF00854.21 ETS86773.1 - 0.0024 16.8 9.2 0.0076 15.1 6.2 2.9 2 1 1 3 3 3 1 POT family CFEM PF05730.11 ETS86774.1 - 2e-08 34.2 9.6 2e-08 34.2 9.6 1.9 2 0 0 2 2 2 1 CFEM domain Mucin PF01456.17 ETS86774.1 - 0.015 15.3 20.1 0.023 14.7 20.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Neurokinin_B PF03823.14 ETS86774.1 - 1.2 9.2 0.0 1.2 9.2 0.0 2.7 2 1 1 3 3 3 0 Neurokinin B DUF962 PF06127.11 ETS86777.1 - 2e-25 88.7 0.0 3.2e-25 88.0 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF962) SHS2_Rpb7-N PF03876.17 ETS86778.1 - 1.8e-15 57.0 0.0 2.7e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 ETS86778.1 - 3.4e-10 40.1 0.0 7.4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain RNase_II_C_S1 PF18614.1 ETS86778.1 - 0.088 12.8 0.4 20 5.2 0.1 2.5 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain LAM_C PF12544.8 ETS86779.1 - 0.0003 21.0 0.0 0.00068 19.8 0.0 1.6 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.21 ETS86779.1 - 0.002 18.5 0.2 0.012 16.0 0.2 2.2 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 ETS86779.1 - 0.024 14.8 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF1930 PF09122.10 ETS86779.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1930) TAF4 PF05236.14 ETS86781.1 - 0.078 12.7 4.2 0.14 11.9 4.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF434 PF04256.12 ETS86781.1 - 0.23 11.2 0.6 0.57 9.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF434) Sortilin-Vps10 PF15902.5 ETS86782.1 - 1.5e-280 930.4 21.2 2.6e-143 478.1 8.6 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 ETS86782.1 - 8.4e-84 280.1 19.5 2e-46 158.5 9.4 2.5 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 ETS86782.1 - 5e-10 37.9 39.2 1.8 8.9 0.3 12.6 12 0 0 12 12 12 6 BNR/Asp-box repeat CHB_HEX_C PF03174.13 ETS86782.1 - 0.00042 20.2 4.8 0.028 14.4 0.2 3.9 4 0 0 4 4 4 2 Chitobiase/beta-hexosaminidase C-terminal domain BNR_6 PF15899.5 ETS86782.1 - 0.00057 19.7 5.4 8.1 6.8 0.1 6.3 6 0 0 6 6 6 1 BNR-Asp box repeat BNR_2 PF13088.6 ETS86782.1 - 0.011 15.0 15.4 5.3 6.3 0.2 6.7 6 2 1 7 7 7 0 BNR repeat-like domain CP12 PF02672.15 ETS86782.1 - 0.033 14.9 0.4 0.087 13.6 0.4 1.7 1 0 0 1 1 1 0 CP12 domain WD40 PF00400.32 ETS86784.1 - 8.7e-18 64.4 13.8 0.00058 20.6 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS86784.1 - 8.1e-08 32.5 0.0 0.04 14.2 0.0 4.9 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 ETS86784.1 - 0.053 13.3 0.2 1.1 8.9 0.0 2.5 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain RRM_1 PF00076.22 ETS86785.1 - 1.1e-08 34.8 0.0 2.6e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ETS86785.1 - 3e-05 23.6 0.0 4.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 ETS86785.1 - 0.095 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 Autophagy_act_C PF03987.15 ETS86786.1 - 1.6e-13 51.0 0.1 3.4e-13 49.9 0.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Glyco_hydro_47 PF01532.20 ETS86787.1 - 8.5e-169 562.3 0.1 1.1e-168 561.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AA_permease PF00324.21 ETS86788.1 - 8.8e-143 476.3 39.7 1e-142 476.2 39.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ETS86788.1 - 7.3e-37 127.2 41.1 9.1e-37 126.9 41.1 1.1 1 0 0 1 1 1 1 Amino acid permease Proteasome_A_N PF10584.9 ETS86789.1 - 0.019 14.6 0.0 0.045 13.4 0.0 1.7 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature LRR_6 PF13516.6 ETS86790.1 - 1.8e-11 43.1 5.1 0.0073 16.3 0.0 6.8 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 ETS86790.1 - 1.6e-10 41.0 4.7 0.03 14.7 0.0 5.4 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ETS86790.1 - 2.8e-06 27.0 10.1 0.28 11.0 0.0 5.0 4 1 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 ETS86790.1 - 5.2e-06 26.3 0.1 11 7.0 0.1 5.5 5 0 0 5 5 5 1 Leucine Rich Repeat SDA1 PF05285.12 ETS86790.1 - 2 7.8 17.5 2.7 7.3 17.5 1.2 1 0 0 1 1 1 0 SDA1 Dynamin_M PF01031.20 ETS86791.1 - 8.1e-112 373.1 0.0 1.5e-111 372.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 ETS86791.1 - 7.3e-55 185.6 0.0 1.8e-54 184.3 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 ETS86791.1 - 2.5e-31 107.7 1.8 6.8e-31 106.3 1.8 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 ETS86791.1 - 9.7e-05 22.4 0.2 0.00039 20.5 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase WD40 PF00400.32 ETS86793.1 - 1.9e-12 47.4 4.1 0.14 13.1 0.3 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS86793.1 - 0.00029 21.1 0.1 2.1 8.7 0.0 3.4 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain GGN PF15685.5 ETS86793.1 - 0.14 11.2 0.3 0.19 10.8 0.3 1.1 1 0 0 1 1 1 0 Gametogenetin UAA PF08449.11 ETS86794.1 - 1.2e-106 356.3 6.7 1.5e-106 356.1 6.7 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 ETS86794.1 - 2.9e-05 23.4 2.7 3.8e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.20 ETS86794.1 - 0.75 10.0 26.7 3.2 7.9 1.7 4.0 3 1 0 3 3 3 0 EamA-like transporter family TssN PF17555.2 ETS86794.1 - 5.7 6.2 9.5 0.88 8.9 3.3 2.2 2 1 0 2 2 2 0 Type VI secretion system, TssN A_deaminase PF00962.22 ETS86795.1 - 3.3e-123 411.2 0.1 4.9e-123 410.7 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Prefoldin_2 PF01920.20 ETS86796.1 - 5.8e-16 58.4 5.5 7.1e-16 58.1 5.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit IFT20 PF14931.6 ETS86796.1 - 0.043 14.0 0.9 0.043 14.0 0.9 2.1 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 FlxA PF14282.6 ETS86796.1 - 0.094 12.7 14.4 0.36 10.9 1.5 2.1 2 0 0 2 2 2 0 FlxA-like protein DUF3726 PF12525.8 ETS86796.1 - 0.099 12.8 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3726) Sacchrp_dh_NADP PF03435.18 ETS86796.1 - 0.12 12.7 0.9 2.4 8.4 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Fib_alpha PF08702.10 ETS86796.1 - 0.13 12.4 0.4 0.13 12.4 0.4 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4600 PF15372.6 ETS86796.1 - 0.18 12.3 5.7 2.1 8.8 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) DUF2681 PF10883.8 ETS86796.1 - 0.28 11.6 8.5 0.35 11.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) ADIP PF11559.8 ETS86796.1 - 1.7 8.7 11.4 1.8 8.7 1.3 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc24 PF08286.11 ETS86796.1 - 5.2 7.4 7.4 3.4 8.0 1.5 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF16 PF01519.16 ETS86796.1 - 6.9 7.2 11.8 0.22 12.0 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Mito_carr PF00153.27 ETS86798.1 - 5.9e-53 176.8 3.1 3.8e-19 68.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Dor1 PF04124.12 ETS86799.1 - 3.3e-57 193.7 3.0 7.8e-45 153.0 3.1 2.2 2 0 0 2 2 2 2 Dor1-like family TRAM_LAG1_CLN8 PF03798.16 ETS86800.1 - 5.3e-50 169.9 15.3 5.3e-50 169.9 15.3 1.4 2 0 0 2 2 2 1 TLC domain DUF937 PF06078.11 ETS86801.1 - 0.0062 17.2 11.7 0.008 16.8 11.7 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF937) Cnd2 PF05786.14 ETS86801.1 - 0.0064 15.2 2.5 0.0078 14.9 2.5 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 DUF4611 PF15387.6 ETS86801.1 - 0.032 14.5 5.4 0.073 13.3 3.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SH3_1 PF00018.28 ETS86802.1 - 1.2e-35 120.8 13.3 2.5e-13 49.4 0.2 4.6 5 0 0 5 5 5 3 SH3 domain SHD1 PF03983.12 ETS86802.1 - 9.8e-33 111.8 0.1 1.7e-32 111.1 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 ETS86802.1 - 3.5e-31 106.8 9.6 1.8e-11 43.7 0.3 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 ETS86802.1 - 2.8e-24 84.5 0.4 8.3e-09 35.0 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.11 ETS86802.1 - 7e-08 32.8 151.9 4.8e-06 26.9 35.1 6.5 1 1 3 5 5 5 3 Domain of unknown function (DUF1720) SH3_10 PF17902.1 ETS86802.1 - 8.3e-06 25.8 0.1 0.3 11.2 0.0 3.4 3 0 0 3 3 3 2 SH3 domain SAM_4 PF18017.1 ETS86802.1 - 9.8e-05 22.3 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 ETS86802.1 - 0.00032 20.9 6.8 0.017 15.4 2.0 3.3 3 0 0 3 3 3 1 Bacterial SH3 domain Rpp20 PF12328.8 ETS86802.1 - 0.0085 16.1 0.4 0.018 15.0 0.4 1.5 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Ceramidase PF05875.12 ETS86803.1 - 4.9e-89 298.3 8.0 5.5e-89 298.1 8.0 1.0 1 0 0 1 1 1 1 Ceramidase DUF2157 PF09925.9 ETS86803.1 - 0.046 13.5 4.1 0.35 10.6 2.5 2.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) DUF4131 PF13567.6 ETS86803.1 - 0.055 13.1 3.7 0.32 10.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) GT87 PF09594.10 ETS86803.1 - 2.4 7.8 10.2 2.9 7.5 0.7 2.7 3 0 0 3 3 3 0 Glycosyltransferase family 87 TMF_TATA_bd PF12325.8 ETS86804.1 - 3.7e-41 139.9 8.6 3.7e-41 139.9 8.6 6.6 2 1 7 9 9 9 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 ETS86804.1 - 1.3e-15 57.2 10.2 1.3e-15 57.2 10.2 8.8 5 4 4 9 9 9 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 ETS86804.1 - 0.0018 18.5 5.0 0.0018 18.5 5.0 6.2 3 1 4 7 7 5 1 Autophagy protein 16 (ATG16) HSBP1 PF06825.12 ETS86804.1 - 0.023 14.5 7.5 0.091 12.6 0.1 4.5 5 0 0 5 5 5 0 Heat shock factor binding protein 1 TPR_MLP1_2 PF07926.12 ETS86804.1 - 0.097 12.7 96.1 0.1 12.7 17.3 6.8 2 2 1 5 5 5 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 ETS86804.1 - 0.31 11.5 32.0 0.25 11.8 0.4 7.0 6 3 0 6 6 6 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 ETS86804.1 - 0.36 9.7 92.4 0.6 8.9 8.6 5.6 2 1 3 5 5 5 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 ETS86804.1 - 5 6.9 72.0 0.39 10.5 2.0 7.0 3 2 5 8 8 8 0 Phage minor structural protein GP20 Filament PF00038.21 ETS86804.1 - 8.2 5.9 80.8 1.6 8.3 14.4 5.6 2 1 1 3 3 3 0 Intermediate filament protein ThiS PF02597.20 ETS86804.1 - 9.3 7.0 6.5 4.9 7.9 0.4 3.8 2 2 0 2 2 2 0 ThiS family DUF812 PF05667.11 ETS86804.1 - 9.3 5.0 73.6 0.11 11.3 0.3 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF812) Ank_5 PF13857.6 ETS86805.1 - 4.7e-33 112.8 1.2 9.8e-10 38.5 0.0 4.7 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS86805.1 - 7.4e-31 106.1 1.9 2.6e-09 37.4 0.1 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS86805.1 - 1.2e-30 105.9 0.3 2.3e-10 40.9 0.0 3.7 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS86805.1 - 1.4e-28 95.8 0.0 0.00055 20.2 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 ETS86805.1 - 1.2e-24 85.6 0.9 2.3e-05 24.6 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat DUF1491 PF07372.12 ETS86805.1 - 0.13 12.6 0.4 1.9 8.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1491) WD40 PF00400.32 ETS86806.1 - 3.7e-45 151.0 13.2 9.7e-09 35.7 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS86806.1 - 7.5e-06 26.2 0.4 1.2 9.5 0.1 5.1 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ETS86806.1 - 0.00097 17.9 1.6 4.4 5.8 0.0 4.0 1 1 3 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 ETS86806.1 - 0.047 13.0 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain PQQ_3 PF13570.6 ETS86806.1 - 0.11 13.0 0.0 13 6.5 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain AAA PF00004.29 ETS86807.1 - 9.1e-16 58.5 0.0 1.5e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 ETS86807.1 - 3e-11 43.3 0.1 1.5e-10 41.1 0.1 2.1 2 0 0 2 2 2 1 AAA lid domain AAA_16 PF13191.6 ETS86807.1 - 5.4e-10 39.9 0.1 9.1e-09 35.9 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ETS86807.1 - 2.7e-08 34.2 0.0 6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain BAH PF01426.18 ETS86807.1 - 2.4e-06 27.4 0.0 5.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 ETS86807.1 - 0.0065 16.8 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETS86807.1 - 0.017 15.6 0.0 0.047 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ETS86807.1 - 0.023 14.5 0.1 0.069 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 ETS86807.1 - 0.025 14.5 0.0 0.42 10.5 0.0 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 ETS86807.1 - 0.045 13.0 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 ETS86807.1 - 0.071 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ETS86807.1 - 0.08 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_32 PF13654.6 ETS86807.1 - 0.16 10.7 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Prefoldin PF02996.17 ETS86809.1 - 1.4e-23 83.1 0.1 2.1e-23 82.5 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF1664 PF07889.12 ETS86809.1 - 0.0033 17.4 0.3 1.4 9.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 ETS86809.1 - 0.055 13.7 1.9 1.6 8.9 1.9 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family SSF PF00474.17 ETS86810.1 - 5e-19 68.4 28.0 6.8e-19 68.0 28.0 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family ABC2_membrane PF01061.24 ETS86811.1 - 1e-82 276.6 63.8 5e-44 150.2 19.6 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 ETS86811.1 - 1.6e-33 116.1 0.0 2.2e-15 57.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ETS86811.1 - 4.5e-28 97.0 10.5 1.4e-23 82.6 0.1 3.8 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 ETS86811.1 - 7e-12 45.8 0.5 1.9e-11 44.4 0.5 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 ETS86811.1 - 3.7e-07 30.2 0.0 0.0098 15.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ETS86811.1 - 4.3e-06 26.7 0.1 0.00018 21.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ETS86811.1 - 3.8e-05 24.1 0.1 0.0015 18.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 ETS86811.1 - 9.6e-05 22.4 0.8 0.018 15.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 ETS86811.1 - 0.00026 20.7 0.2 0.35 10.7 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 ETS86811.1 - 0.00033 20.9 0.0 0.0014 18.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETS86811.1 - 0.00045 20.8 0.0 0.014 16.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ETS86811.1 - 0.00046 20.5 0.1 0.054 13.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.7 ETS86811.1 - 0.00088 18.5 14.1 0.00088 18.5 14.1 3.1 3 1 1 4 4 3 1 ABC-2 family transporter protein AAA_33 PF13671.6 ETS86811.1 - 0.0013 18.9 0.1 0.033 14.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 ETS86811.1 - 0.0015 18.2 0.1 0.0072 15.9 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 ETS86811.1 - 0.0021 17.6 0.5 0.032 13.6 0.0 2.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 ETS86811.1 - 0.0099 15.6 1.5 0.8 9.4 0.3 2.8 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 ETS86811.1 - 0.015 15.2 0.2 0.15 12.0 0.1 2.2 2 0 0 2 2 2 0 NACHT domain GBP PF02263.19 ETS86811.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_24 PF13479.6 ETS86811.1 - 0.027 14.2 0.0 0.44 10.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 ETS86811.1 - 0.041 13.4 0.0 0.29 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 ETS86811.1 - 0.066 12.5 0.3 0.21 10.8 0.1 1.8 2 0 0 2 2 2 0 Septin TsaE PF02367.17 ETS86811.1 - 0.072 13.1 0.4 0.44 10.5 0.1 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 ETS86811.1 - 0.084 12.0 0.2 1.2 8.3 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 ETS86811.1 - 0.12 11.7 0.3 3.6 6.9 0.2 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 ETS86811.1 - 0.17 12.3 1.2 8.7 6.8 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 ETS86811.1 - 0.19 12.2 0.1 1.6 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 ETS86811.1 - 0.22 11.1 0.6 0.48 9.9 0.1 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.23 ETS86811.1 - 0.24 11.4 0.8 0.99 9.4 0.1 2.2 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.12 ETS86811.1 - 0.41 9.9 3.2 0.44 9.8 0.2 2.3 3 0 0 3 3 2 0 Zeta toxin Kinesin PF00225.23 ETS86812.1 - 2.7e-63 213.9 0.0 9.6e-63 212.1 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ETS86812.1 - 9.5e-36 123.0 0.0 1.9e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding TMV_coat PF00721.21 ETS86812.1 - 0.02 14.7 1.6 0.034 14.0 0.9 1.7 1 1 0 1 1 1 0 Virus coat protein (TMV like) AAA_16 PF13191.6 ETS86812.1 - 0.025 14.9 0.1 0.19 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 ETS86812.1 - 0.034 14.1 0.5 0.54 10.1 0.0 2.7 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea CTP_transf_like PF01467.26 ETS86812.1 - 0.13 12.4 0.1 0.32 11.2 0.1 1.6 1 0 0 1 1 1 0 Cytidylyltransferase-like PspB PF06667.12 ETS86812.1 - 0.24 11.5 2.6 0.2 11.7 0.3 2.0 2 0 0 2 2 2 0 Phage shock protein B AAA_22 PF13401.6 ETS86812.1 - 0.28 11.5 0.0 0.28 11.5 0.0 2.6 3 1 0 3 3 3 0 AAA domain FAD_binding_3 PF01494.19 ETS86813.1 - 1.6e-27 96.7 0.1 1.7e-17 63.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 ETS86813.1 - 2.9e-09 37.0 2.6 5e-05 23.0 3.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS86813.1 - 2.8e-08 33.4 0.9 2e-05 24.0 0.2 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS86813.1 - 5e-06 26.7 0.5 1.3e-05 25.4 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ETS86813.1 - 1.3e-05 25.7 0.2 0.00034 21.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS86813.1 - 0.00013 20.8 0.1 0.00023 20.0 0.1 1.4 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 ETS86813.1 - 0.00031 19.9 2.4 0.00062 19.0 2.4 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 ETS86813.1 - 0.00041 19.6 0.6 0.00057 19.1 0.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Rossmann-like PF10727.9 ETS86813.1 - 0.0014 18.5 0.1 0.004 17.0 0.1 1.8 1 0 0 1 1 1 1 Rossmann-like domain 3HCDH_N PF02737.18 ETS86813.1 - 0.0028 17.6 0.4 0.0053 16.7 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ETS86813.1 - 0.0052 16.1 1.5 0.013 14.8 1.2 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 ETS86813.1 - 0.0079 15.1 1.6 0.13 11.1 0.3 2.7 2 1 1 3 3 3 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 ETS86813.1 - 0.014 14.7 0.3 0.028 13.7 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS86813.1 - 0.022 14.0 0.3 0.061 12.6 0.3 1.7 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 ETS86813.1 - 0.026 14.1 0.9 0.046 13.3 0.4 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 ETS86813.1 - 0.077 12.0 1.4 1.5 7.7 1.2 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.24 ETS86813.1 - 0.092 12.0 0.6 0.15 11.3 0.6 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 ETS86813.1 - 0.11 11.9 3.9 0.22 10.8 3.9 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS86813.1 - 0.16 11.9 1.4 0.88 9.5 0.4 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Glyco_transf_28 PF03033.20 ETS86814.1 - 4.3e-23 81.9 0.0 8.1e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 ETS86814.1 - 8.9e-06 24.8 0.0 1.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ETS86814.1 - 0.0029 17.6 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.11 ETS86814.1 - 0.075 13.4 0.0 12 6.3 0.0 3.2 3 0 0 3 3 3 0 Autophagy-related protein C terminal domain VPS13_C PF16909.5 ETS86814.1 - 0.12 12.1 1.2 0.37 10.5 0.1 2.3 4 0 0 4 4 4 0 Vacuolar-sorting-associated 13 protein C-terminal Peroxidase_2 PF01328.17 ETS86815.1 - 3.5e-52 177.6 0.1 4.5e-52 177.3 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 EcKinase PF02958.20 ETS86816.1 - 2.4e-11 43.5 0.0 2e-07 30.7 0.0 2.6 2 1 0 2 2 2 2 Ecdysteroid kinase APH PF01636.23 ETS86816.1 - 1.8e-09 37.9 0.0 3.9e-09 36.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETS86816.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 ETS86816.1 - 0.065 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RHH_5 PF07878.11 ETS86816.1 - 0.088 12.7 0.1 0.73 9.8 0.0 2.2 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 SR-25 PF10500.9 ETS86816.1 - 0.77 9.3 13.2 0.23 11.1 8.9 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Dehydrin PF00257.19 ETS86816.1 - 0.88 10.1 4.9 2.5 8.7 4.9 1.7 1 0 0 1 1 1 0 Dehydrin IMUP PF15761.5 ETS86816.1 - 0.93 10.2 11.2 2.5 8.8 11.2 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF515 PF04415.12 ETS86816.1 - 5.9 5.2 5.5 9.2 4.5 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MFS_1 PF07690.16 ETS86817.1 - 1.8e-46 158.7 40.2 1.8e-46 158.7 40.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS86817.1 - 2.5e-14 53.0 7.2 2.5e-14 53.0 7.2 2.5 2 1 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 ETS86817.1 - 0.0034 15.9 5.5 0.0058 15.1 5.5 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector TRI12 PF06609.13 ETS86817.1 - 0.004 15.6 3.4 0.0061 15.0 3.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Arylesterase PF01731.20 ETS86818.1 - 0.0097 16.1 0.0 0.12 12.6 0.0 2.9 2 1 0 2 2 2 1 Arylesterase Peptidase_C48 PF02902.19 ETS86819.1 - 5.9e-19 68.8 0.1 9.6e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SLX9 PF15341.6 ETS86820.1 - 4.5e-35 120.9 9.7 6.7e-35 120.4 9.7 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 ThiF PF00899.21 ETS86821.1 - 2.2e-59 200.8 0.0 3.2e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 ETS86821.1 - 8.2e-11 42.4 0.0 2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.20 ETS86821.1 - 0.012 15.7 0.1 0.18 11.8 0.0 2.4 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 ETS86821.1 - 0.1 13.0 0.0 0.38 11.2 0.0 1.9 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 ETS86821.1 - 0.21 10.8 1.2 0.33 10.1 1.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pam17 PF08566.10 ETS86822.1 - 8e-61 204.7 0.0 1.1e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Chromo PF00385.24 ETS86823.1 - 2.2e-12 46.7 0.7 1.2e-10 41.1 0.2 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Vac7 PF12751.7 ETS86823.1 - 0.089 12.2 4.2 0.95 8.8 0.0 2.2 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 RPN6_C_helix PF18503.1 ETS86824.1 - 0.11 12.3 1.0 0.26 11.1 1.0 1.7 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain Nab6_mRNP_bdg PF10567.9 ETS86824.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 RNA-recognition motif FMN_dh PF01070.18 ETS86825.1 - 2.6e-111 372.0 0.0 3.2e-111 371.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ETS86825.1 - 3.6e-21 75.1 0.0 7e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 ETS86825.1 - 1.5e-05 24.3 0.1 2.4e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 ETS86825.1 - 0.0002 20.5 0.4 0.0025 16.9 0.1 2.3 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 ETS86825.1 - 0.0031 16.9 0.0 0.65 9.3 0.0 2.9 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 ETS86825.1 - 0.007 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glyco_hydro_16 PF00722.21 ETS86826.1 - 4.1e-12 45.9 0.7 6.9e-12 45.2 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1080 PF06439.11 ETS86826.1 - 0.032 14.3 0.8 0.37 10.9 0.8 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) Dynamin_N PF00350.23 ETS86827.1 - 1.2e-16 61.2 1.9 7e-16 58.7 0.0 2.9 2 2 0 2 2 1 1 Dynamin family MMR_HSR1 PF01926.23 ETS86827.1 - 3.1e-06 27.3 0.0 0.00075 19.6 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETS86827.1 - 0.00032 20.6 0.0 0.0047 16.9 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase IIGP PF05049.13 ETS86827.1 - 0.0023 17.1 0.1 0.0084 15.2 0.0 1.9 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 ETS86827.1 - 0.0038 17.8 0.0 0.0038 17.8 0.0 3.0 2 1 0 2 2 1 1 ABC transporter AAA_22 PF13401.6 ETS86827.1 - 0.03 14.6 0.8 0.99 9.7 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_21 PF13304.6 ETS86827.1 - 0.065 13.0 1.7 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system CUT PF02376.15 ETS86827.1 - 0.069 13.3 0.0 0.23 11.6 0.0 1.9 1 0 0 1 1 1 0 CUT domain AAA_16 PF13191.6 ETS86827.1 - 0.076 13.4 7.3 0.16 12.4 0.0 4.1 4 1 0 4 4 4 0 AAA ATPase domain AAA_23 PF13476.6 ETS86827.1 - 0.67 10.4 0.0 0.67 10.4 0.0 3.4 4 1 0 4 4 3 0 AAA domain Prefoldin PF02996.17 ETS86827.1 - 4.4 7.2 10.6 40 4.1 0.1 3.2 2 0 0 2 2 2 0 Prefoldin subunit DUF4079 PF13301.6 ETS86828.1 - 0.13 12.5 10.9 0.16 12.1 8.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) FeoB_associated PF12669.7 ETS86828.1 - 1 9.8 0.0 1 9.8 0.0 3.1 3 0 0 3 3 3 0 FeoB-associated Cys-rich membrane protein Thioredoxin_7 PF13899.6 ETS86829.1 - 5.2e-15 55.4 0.0 1.2e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 ETS86829.1 - 6.1e-12 45.1 0.0 2.2e-11 43.4 0.1 1.9 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.20 ETS86829.1 - 7.1e-06 26.1 0.0 1.8e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.15 ETS86829.1 - 0.00011 22.2 0.0 0.00018 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 ETS86829.1 - 0.0031 17.9 0.0 0.0066 16.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain YL1 PF05764.13 ETS86829.1 - 0.45 10.6 5.0 9 6.3 1.6 2.4 2 0 0 2 2 2 0 YL1 nuclear protein Ecm29 PF13001.7 ETS86830.1 - 2.6e-124 415.7 1.6 7.8e-123 410.8 0.0 3.6 3 1 0 3 3 3 1 Proteasome stabiliser HEAT PF02985.22 ETS86830.1 - 1.8e-07 30.8 1.6 2.1 8.8 0.0 7.1 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 ETS86830.1 - 0.00012 22.5 5.9 14 6.4 0.0 8.2 9 1 0 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.6 ETS86830.1 - 0.14 12.5 16.6 3.1 8.3 0.0 7.8 9 0 0 9 9 9 0 HEAT repeats DUF3385 PF11865.8 ETS86830.1 - 0.14 12.0 0.1 3.1 7.7 0.1 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3385) RRM_1 PF00076.22 ETS86831.1 - 1.4e-46 156.1 0.0 1.5e-16 60.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ETS86831.1 - 2.6e-05 24.1 0.0 0.0024 17.8 0.1 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 ETS86831.1 - 4.9e-05 23.3 0.0 0.0019 18.2 0.0 2.8 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 ETS86831.1 - 0.0003 20.8 0.1 0.057 13.5 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 ETS86831.1 - 0.0014 18.5 0.0 0.056 13.3 0.0 2.7 3 0 0 3 3 3 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 ETS86831.1 - 0.026 14.8 0.1 14 5.9 0.0 3.3 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 ETS86831.1 - 0.028 14.0 0.0 0.22 11.1 0.0 2.3 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 ETS86832.1 - 1.7e-68 230.8 0.0 2.7e-68 230.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS86832.1 - 2.2e-50 171.4 0.0 3.5e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ETS86832.1 - 0.0013 17.6 0.0 0.0026 16.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 ETS86832.1 - 0.022 14.9 0.0 0.06 13.5 0.0 1.7 1 0 0 1 1 1 0 ABC1 family Kinase-like PF14531.6 ETS86832.1 - 0.11 11.8 0.0 0.51 9.6 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Methyltransf_23 PF13489.6 ETS86833.1 - 8.8e-22 77.7 0.0 1.4e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS86833.1 - 3.3e-11 43.2 0.0 2.1e-10 40.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS86833.1 - 8.5e-11 42.4 0.0 2.4e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS86833.1 - 1.8e-07 31.7 0.0 4.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS86833.1 - 1.8e-07 31.8 0.0 7e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ETS86833.1 - 0.0078 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ETS86833.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain GidB PF02527.15 ETS86833.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.17 ETS86833.1 - 0.017 14.6 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase CheR PF01739.18 ETS86833.1 - 0.019 14.5 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain FtsJ PF01728.19 ETS86833.1 - 0.021 15.0 0.0 0.092 12.9 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 ETS86833.1 - 0.036 13.8 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 ETS86833.1 - 0.062 12.6 0.0 0.28 10.5 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Esterase_phd PF10503.9 ETS86834.1 - 1.4e-24 86.9 0.2 1.8e-24 86.5 0.2 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ETS86834.1 - 4e-08 33.0 1.2 6.1e-08 32.4 1.2 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family GFO_IDH_MocA PF01408.22 ETS86835.1 - 7.3e-14 52.6 0.0 1.3e-13 51.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ETS86835.1 - 0.0014 18.6 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F420_oxidored PF03807.17 ETS86835.1 - 0.13 12.9 0.1 0.67 10.6 0.1 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sugar_tr PF00083.24 ETS86836.1 - 4.2e-82 276.4 22.4 4.9e-82 276.2 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS86836.1 - 3.4e-16 59.1 26.5 3.4e-16 59.1 26.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 ETS86837.1 - 4.2e-16 58.8 0.1 5.8e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS86837.1 - 0.69 10.1 14.3 6.2 7.0 14.3 2.3 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Melibiase_2 PF16499.5 ETS86838.1 - 8.3e-60 202.4 1.1 1.8e-58 198.0 1.1 2.1 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 ETS86838.1 - 7.2e-11 42.0 0.0 3.8e-09 36.5 0.0 2.6 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 ETS86838.1 - 1.8e-06 27.1 0.0 4.8e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Melibiase TPR_19 PF14559.6 ETS86840.1 - 3.6e-05 24.2 1.2 0.44 11.1 0.4 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS86840.1 - 0.059 13.6 0.1 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 ETS86840.1 - 0.17 12.0 3.5 1.1e+02 3.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 ETS86840.1 - 7.9 7.6 7.7 6.5 7.9 0.9 4.0 4 2 1 5 5 5 0 Tetratricopeptide repeat Adaptin_N PF01602.20 ETS86841.1 - 1.3e-95 320.9 5.5 2.1e-95 320.3 5.5 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 ETS86841.1 - 1.1e-59 200.4 0.2 2.3e-59 199.3 0.2 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 ETS86841.1 - 5.3e-57 191.3 0.0 1.5e-56 189.9 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 ETS86841.1 - 4.3e-14 52.9 2.4 2.3e-09 37.5 0.0 3.0 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ETS86841.1 - 1.8e-08 34.7 0.1 0.00012 22.4 0.0 5.4 3 2 3 6 6 6 2 HEAT repeats Coatomer_g_Cpla PF16381.5 ETS86841.1 - 0.00011 22.3 0.0 0.00031 20.8 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 ETS86841.1 - 0.0016 18.5 0.2 6 7.4 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 ETS86841.1 - 0.022 15.2 1.8 2.7 8.6 0.0 4.2 4 0 0 4 4 4 0 HEAT-like repeat DUF5578 PF17741.1 ETS86841.1 - 0.023 14.1 2.4 1.6 8.1 0.1 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5578) AP4E_app_platf PF14807.6 ETS86841.1 - 0.031 14.6 0.2 0.1 13.0 0.2 1.9 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Mago_nashi PF02792.14 ETS86842.1 - 9.8e-72 239.7 0.1 1.1e-71 239.5 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein Vac_ImportDeg PF09783.9 ETS86843.1 - 6.9e-68 227.5 0.2 8.6e-68 227.2 0.2 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein PM0188 PF11477.8 ETS86843.1 - 0.09 11.9 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Sialyltransferase PMO188 UPF0020 PF01170.18 ETS86844.1 - 3.6e-08 33.3 0.0 1.9e-06 27.7 0.0 2.5 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 MethyltransfD12 PF02086.15 ETS86844.1 - 0.039 13.6 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase SsgA PF04686.12 ETS86844.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Streptomyces sporulation and cell division protein, SsgA Ribonuc_P_40 PF08584.11 ETS86845.1 - 6.4e-54 183.2 0.0 9.7e-54 182.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Ank_5 PF13857.6 ETS86846.1 - 6.6e-09 35.9 0.1 3.2e-07 30.5 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS86846.1 - 2.6e-08 34.3 0.0 3.4e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS86846.1 - 4e-07 30.5 0.5 0.0021 18.6 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS86846.1 - 0.00018 21.7 0.3 0.0014 19.0 0.1 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 ETS86846.1 - 0.026 15.0 0.0 0.066 13.7 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Lipoprotein_18 PF06804.11 ETS86846.1 - 0.092 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 NlpB/DapX lipoprotein Glycos_transf_3 PF00591.21 ETS86847.1 - 3.3e-63 213.6 0.0 5.2e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 ETS86847.1 - 1.9e-11 43.6 0.0 4.1e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain tRNA_lig_CPD PF08302.11 ETS86848.1 - 2.3e-86 289.4 0.1 3.1e-86 289.0 0.1 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 ETS86848.1 - 6.2e-85 284.5 0.0 1.1e-84 283.7 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 ETS86848.1 - 1.6e-56 191.0 0.2 3.1e-56 190.1 0.2 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain PK PF00224.21 ETS86848.1 - 0.047 12.6 0.1 0.08 11.8 0.1 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain ABC_tran PF00005.27 ETS86848.1 - 0.092 13.3 0.7 0.46 11.0 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Ribosomal_L10 PF00466.20 ETS86849.1 - 0.0016 18.6 0.0 0.04 14.1 0.0 2.4 2 1 0 2 2 2 1 Ribosomal protein L10 Imm_superinfect PF14373.6 ETS86850.1 - 0.63 10.0 5.0 1.1 9.2 5.0 1.4 1 0 0 1 1 1 0 Superinfection immunity protein UBD PF16455.5 ETS86851.1 - 2.3e-34 117.8 0.1 4.7e-34 116.8 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 ETS86851.1 - 1e-05 25.2 0.0 6.8e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 ETS86851.1 - 1.2e-05 25.0 0.0 2.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ETS86851.1 - 0.0001 22.8 0.6 0.0001 22.8 0.6 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Bin3 PF06859.12 ETS86853.1 - 1.8e-33 115.4 0.0 2.8e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 ETS86853.1 - 1.5e-11 44.4 0.0 2.1e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS86853.1 - 3.2e-10 40.0 0.0 4.2e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS86853.1 - 1.9e-09 38.1 0.0 3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS86853.1 - 4.5e-08 33.7 0.0 7.3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS86853.1 - 3.3e-07 30.9 0.0 5.5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS86853.1 - 4.3e-05 23.1 0.0 0.00013 21.6 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_9 PF08003.11 ETS86853.1 - 0.021 13.8 0.1 0.039 12.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) PrmA PF06325.13 ETS86853.1 - 0.043 13.2 0.0 0.094 12.1 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 ETS86853.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Pre-SET PF05033.16 ETS86854.1 - 3e-19 69.7 5.2 7.9e-19 68.3 3.3 2.1 2 0 0 2 2 2 1 Pre-SET motif SET PF00856.28 ETS86854.1 - 1.2e-17 64.8 0.0 7.8e-17 62.2 0.0 2.1 1 1 0 1 1 1 1 SET domain Gly-zipper_OmpA PF13436.6 ETS86855.1 - 0.25 11.2 3.8 0.55 10.1 3.8 1.6 1 0 0 1 1 1 0 Glycine-zipper domain ADH_zinc_N PF00107.26 ETS86856.1 - 5e-09 36.2 0.0 1.6e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS86856.1 - 1.5e-06 28.0 0.0 5e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 ETS86856.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase SurE PF01975.17 ETS86858.1 - 1.4e-40 139.2 0.1 1.8e-40 138.8 0.1 1.1 1 0 0 1 1 1 1 Survival protein SurE Kinesin PF00225.23 ETS86859.1 - 8.8e-59 199.1 0.0 1.7e-58 198.2 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ETS86859.1 - 1.9e-11 44.1 0.0 5.8e-09 36.1 0.0 2.5 2 0 0 2 2 2 2 Microtubule binding Tho2 PF11262.8 ETS86859.1 - 0.063 12.5 0.1 0.063 12.5 0.1 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 HALZ PF02183.18 ETS86859.1 - 0.17 12.1 0.9 0.54 10.5 0.9 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper PKI PF02827.16 ETS86859.1 - 0.72 10.1 3.4 0.73 10.1 0.2 2.6 3 0 0 3 3 3 0 cAMP-dependent protein kinase inhibitor SlyX PF04102.12 ETS86859.1 - 4.1 8.1 6.1 13 6.5 1.5 3.2 3 0 0 3 3 3 0 SlyX PRORP PF16953.5 ETS86860.1 - 0.029 13.9 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-only RNase P TipE PF16972.5 ETS86860.1 - 7.3 5.7 9.7 15 4.6 9.7 1.4 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE Bac_rhamnosid6H PF17389.2 ETS86861.1 - 4.1e-114 381.4 0.0 6.5e-114 380.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 ETS86861.1 - 1.5e-52 177.9 0.2 2.8e-52 177.0 0.2 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 ETS86861.1 - 1.9e-21 75.9 0.0 7.9e-21 74.0 0.0 2.0 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 ETS86861.1 - 1.3e-17 63.3 0.1 5.8e-17 61.3 0.1 2.0 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF3344 PF11824.8 ETS86861.1 - 0.099 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) Glyco_hydro_31 PF01055.26 ETS86862.1 - 3.6e-105 352.7 0.3 5e-105 352.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 ETS86862.1 - 1e-05 25.8 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 ETS86862.1 - 0.00029 21.1 0.6 0.0015 18.8 0.0 2.5 2 1 0 2 2 2 1 Galactose mutarotase-like ADH_zinc_N PF00107.26 ETS86863.1 - 2.4e-06 27.5 0.0 5.8e-06 26.3 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS86863.1 - 4.1e-05 24.6 0.0 0.00016 22.8 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS86863.1 - 8e-05 22.5 0.3 0.00021 21.2 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain B12-binding PF02310.19 ETS86863.1 - 0.072 13.1 0.0 0.42 10.7 0.0 2.0 1 1 1 2 2 2 0 B12 binding domain RTA1 PF04479.13 ETS86864.1 - 6.6e-76 254.5 5.6 9e-76 254.1 5.6 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF1282 PF06930.12 ETS86864.1 - 4.7 7.0 10.3 8.7 6.1 0.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1282) Promethin PF16015.5 ETS86864.1 - 5.7 6.9 12.5 2.7 8.0 0.0 3.8 4 0 0 4 4 4 0 Promethin Nop52 PF05997.12 ETS86865.1 - 6.5e-55 186.3 0.1 8.1e-55 185.9 0.1 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Upf2 PF04050.14 ETS86865.1 - 0.014 16.1 1.7 0.026 15.3 1.7 1.3 1 0 0 1 1 1 0 Up-frameshift suppressor 2 TAN PF11640.8 ETS86865.1 - 0.038 14.1 0.1 0.075 13.2 0.1 1.4 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair DAGK_cat PF00781.24 ETS86866.1 - 1.7e-24 85.9 0.0 6.7e-24 83.9 0.0 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain POC1 PF10450.9 ETS86866.1 - 0.087 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 POC1 chaperone zf-CHY PF05495.12 ETS86867.1 - 6.5e-11 42.6 12.2 1e-10 41.9 12.2 1.3 1 0 0 1 1 1 1 CHY zinc finger DUF2054 PF10218.9 ETS86867.1 - 5.7 7.0 15.7 5.4 7.1 4.5 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2054) zinc_ribbon_4 PF13717.6 ETS86867.1 - 8.1 6.5 11.8 5.8 6.9 0.2 3.3 4 0 0 4 4 4 0 zinc-ribbon domain Ish1 PF10281.9 ETS86868.1 - 9.6e-86 281.8 26.9 1.1e-13 51.3 0.1 8.5 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.27 ETS86868.1 - 3.5e-10 39.4 0.0 0.82 9.5 0.0 7.8 10 0 0 10 10 10 3 SAP domain HeH PF12949.7 ETS86868.1 - 8e-07 28.7 0.1 3.5 7.4 0.0 5.9 6 0 0 6 6 6 3 HeH/LEM domain Slx4 PF09494.10 ETS86868.1 - 5e-05 23.2 3.2 40 4.3 0.2 6.5 7 1 0 7 7 7 0 Slx4 endonuclease Thymopoietin PF08198.11 ETS86868.1 - 0.087 12.4 0.0 5.3 6.7 0.0 3.5 3 0 0 3 3 3 0 Thymopoietin protein DUF2497 PF10691.9 ETS86868.1 - 0.98 9.9 3.4 2.1e+02 2.4 0.1 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF2497) Aa_trans PF01490.18 ETS86870.1 - 3.4e-29 101.8 19.2 6.1e-29 101.0 19.2 1.4 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF604 PF04646.12 ETS86871.1 - 1.7e-09 37.4 0.0 4.3e-07 29.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function, DUF604 Fringe PF02434.16 ETS86871.1 - 1.3e-05 24.7 0.0 3.2e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Fringe-like Glyco_transf_25 PF01755.17 ETS86872.1 - 9.1e-06 25.7 0.0 0.00098 19.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF4448 PF14610.6 ETS86873.1 - 0.0018 18.1 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Herpes_gE PF02480.16 ETS86873.1 - 0.0039 16.0 0.1 0.0054 15.5 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 ETS86873.1 - 0.021 14.7 1.5 0.036 14.0 1.5 1.4 1 0 0 1 1 1 0 TMEM154 protein family NICE-1 PF15845.5 ETS86873.1 - 0.047 14.5 1.3 0.047 14.5 1.3 2.1 1 1 1 2 2 2 0 Cysteine-rich C-terminal 1 family MGC-24 PF05283.11 ETS86873.1 - 0.09 13.2 10.8 0.16 12.4 10.8 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin PF01456.17 ETS86873.1 - 0.16 11.9 27.4 0.049 13.6 24.7 1.4 2 0 0 2 2 2 0 Mucin-like glycoprotein VSP PF03302.13 ETS86873.1 - 0.57 9.0 11.2 1.1 8.0 11.2 1.4 1 1 0 1 1 1 0 Giardia variant-specific surface protein SKG6 PF08693.10 ETS86873.1 - 1 8.8 5.1 0.16 11.4 0.8 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Med3 PF11593.8 ETS86873.1 - 6.6 5.8 12.6 8.3 5.5 12.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Peptidase_M13 PF01431.21 ETS86874.1 - 9.2e-44 149.5 1.4 1.8e-43 148.5 1.4 1.5 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13_N PF05649.13 ETS86874.1 - 1.6e-33 117.0 0.2 2.3e-33 116.4 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M13 Mannosyl_trans3 PF11051.8 ETS86875.1 - 0.074 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative DUF1857 PF08982.11 ETS86877.1 - 9.6e-57 191.0 0.0 1.1e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Aldo_ket_red PF00248.21 ETS86878.1 - 5.9e-43 147.1 0.0 8.8e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0149 PF03695.13 ETS86878.1 - 0.043 14.1 0.3 0.33 11.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) Pkinase PF00069.25 ETS86880.1 - 8.9e-21 74.4 0.0 1.7e-09 37.4 0.0 3.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS86880.1 - 1.9e-05 24.1 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 ETS86880.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hydrophobin_2 PF06766.11 ETS86881.1 - 1.8e-24 85.5 10.9 2.3e-24 85.1 10.9 1.2 1 0 0 1 1 1 1 Fungal hydrophobin NARP1 PF12569.8 ETS86882.1 - 1.3e-195 651.3 28.7 9.8e-195 648.3 18.8 2.8 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 ETS86882.1 - 8.3e-22 77.5 31.1 0.0001 22.8 0.1 7.4 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_16 PF13432.6 ETS86882.1 - 4.4e-20 72.0 27.4 0.00027 21.5 0.4 9.4 6 2 5 11 11 11 7 Tetratricopeptide repeat TPR_14 PF13428.6 ETS86882.1 - 6e-19 67.1 26.3 0.00014 22.4 0.0 11.0 7 3 5 12 12 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 ETS86882.1 - 1.3e-16 60.0 14.8 8.5e-08 31.8 0.0 6.7 7 0 0 7 7 7 3 TPR repeat TPR_9 PF13371.6 ETS86882.1 - 2.7e-16 59.5 5.3 5.2e-05 23.3 0.4 6.3 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 ETS86882.1 - 3.8e-16 57.8 51.3 2e-06 27.5 0.1 12.5 13 2 1 14 14 13 5 Tetratricopeptide repeat TPR_1 PF00515.28 ETS86882.1 - 1.4e-15 56.3 29.7 1.4e-06 27.8 0.2 9.9 10 1 0 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 ETS86882.1 - 4.6e-13 49.3 22.0 0.12 12.7 0.0 7.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 ETS86882.1 - 8.6e-12 44.6 12.8 0.047 14.1 0.0 9.4 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 ETS86882.1 - 1.1e-11 43.9 29.9 1.6e-05 24.8 0.2 9.9 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_15 PF13429.6 ETS86882.1 - 1.4e-11 44.2 17.9 0.0009 18.5 4.1 5.3 3 1 1 4 4 4 4 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS86882.1 - 3.4e-11 43.2 23.6 0.00084 19.5 1.8 6.2 3 1 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ETS86882.1 - 2.9e-06 26.9 15.2 0.24 11.5 0.0 8.0 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 ETS86882.1 - 0.00014 21.7 9.0 6.3 6.8 0.1 6.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 ETS86882.1 - 0.00017 21.9 1.6 0.66 10.8 0.4 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 ETS86882.1 - 0.0066 17.0 40.0 0.15 12.7 0.1 10.6 12 0 0 12 12 11 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 ETS86882.1 - 0.03 14.0 4.4 17 5.1 0.1 4.8 5 0 0 5 5 5 0 Bacterial type III secretion protein (HrpB1_HrpK) Acetyltransf_11 PF13720.6 ETS86882.1 - 0.11 13.0 0.0 0.74 10.3 0.0 2.5 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Alkyl_sulf_dimr PF14863.6 ETS86882.1 - 0.21 12.0 14.2 1.6 9.1 0.3 4.5 5 0 0 5 5 3 0 Alkyl sulfatase dimerisation CCDC53 PF10152.9 ETS86882.1 - 0.42 11.0 5.5 3.7 8.0 1.9 2.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Fis1_TPR_C PF14853.6 ETS86882.1 - 5.7 7.1 21.0 9.1 6.4 0.1 6.1 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat Cid2 PF09774.9 ETS86883.1 - 2.2e-53 180.9 0.9 2.7e-53 180.7 0.9 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 AAA PF00004.29 ETS86884.1 - 9.9e-40 136.0 0.0 2e-39 135.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 ETS86884.1 - 4.1e-19 68.3 0.1 8.2e-19 67.3 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 ETS86884.1 - 4.6e-08 32.7 0.0 1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 ETS86884.1 - 0.00013 22.4 1.7 0.02 15.3 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 ETS86884.1 - 0.00014 21.9 1.3 0.00072 19.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ETS86884.1 - 0.00037 20.3 0.0 0.00092 19.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ETS86884.1 - 0.0018 18.4 0.4 0.011 15.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 ETS86884.1 - 0.0057 16.1 0.2 0.081 12.4 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 ETS86884.1 - 0.008 15.6 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 ETS86884.1 - 0.013 15.8 4.9 0.083 13.2 0.0 3.0 3 1 0 4 4 4 0 AAA domain DUF815 PF05673.13 ETS86884.1 - 0.013 14.7 0.0 0.027 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 ETS86884.1 - 0.014 15.5 0.0 0.034 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2115 PF09888.9 ETS86884.1 - 0.073 13.6 0.6 0.15 12.6 0.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) IstB_IS21 PF01695.17 ETS86884.1 - 0.076 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 ETS86884.1 - 0.11 12.0 0.0 0.32 10.5 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region JIP_LZII PF16471.5 ETS86884.1 - 0.2 11.8 4.5 0.58 10.4 4.5 1.7 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II AAA_11 PF13086.6 ETS86884.1 - 0.6 9.8 0.0 0.6 9.8 0.0 2.7 2 1 0 3 3 3 0 AAA domain Cyclin PF08613.11 ETS86885.1 - 2.5e-09 37.7 0.0 4.9e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ETS86885.1 - 0.00025 20.8 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain PHD PF00628.29 ETS86886.1 - 3.8e-08 33.1 9.2 6.2e-08 32.4 9.2 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 ETS86886.1 - 0.0028 17.5 5.3 0.0028 17.5 5.3 1.7 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 ETS86886.1 - 0.071 13.3 4.6 0.13 12.5 4.6 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_1 PF14446.6 ETS86886.1 - 0.17 11.8 4.8 0.35 10.8 4.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 ETS86886.1 - 0.27 10.8 15.0 0.05 13.2 10.5 2.1 2 1 0 2 2 2 0 PHD-finger AT_hook PF02178.19 ETS86886.1 - 0.66 10.1 15.6 0.42 10.6 6.1 3.4 2 0 0 2 2 2 0 AT hook motif zf-PHD-like PF15446.6 ETS86886.1 - 0.71 9.5 10.5 0.28 10.8 5.1 2.5 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Glyco_hydro_17 PF00332.18 ETS86887.1 - 4.8e-05 23.1 0.9 0.00047 19.8 0.9 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.13 ETS86887.1 - 0.043 12.8 0.1 0.066 12.2 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Isochorismatase PF00857.20 ETS86888.1 - 7.9e-25 88.0 0.0 9.1e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Sulfatase PF00884.23 ETS86889.1 - 2e-56 191.7 1.4 2.7e-56 191.2 1.4 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 ETS86889.1 - 0.00063 20.0 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Aminotran_3 PF00202.21 ETS86890.1 - 1.2e-49 169.1 0.4 5.4e-48 163.6 0.4 2.1 1 1 0 1 1 1 1 Aminotransferase class-III EutQ PF06249.12 ETS86890.1 - 0.038 13.8 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ YtfJ_HI0045 PF09695.10 ETS86890.1 - 0.053 13.2 0.4 0.091 12.4 0.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) adh_short PF00106.25 ETS86891.1 - 1.5e-17 63.8 0.1 1.1e-16 60.9 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS86891.1 - 1.2e-07 31.5 0.0 2.1e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS86891.1 - 3.2e-06 27.2 0.2 4.8e-06 26.6 0.2 1.2 1 0 0 1 1 1 1 KR domain CRC_subunit PF08624.10 ETS86892.1 - 1.9e-51 174.0 0.0 2.7e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CDC45 PF02724.14 ETS86892.1 - 1.7 6.8 3.0 2.3 6.4 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_18 PF00704.28 ETS86893.1 - 6.8e-25 88.4 3.0 6.8e-25 88.4 3.0 2.1 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_1 PF00734.18 ETS86893.1 - 4e-10 39.5 13.2 1.4e-09 37.8 13.2 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain TauD PF02668.16 ETS86894.1 - 3e-29 102.6 0.4 4e-29 102.2 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Arylsulfotran_2 PF14269.6 ETS86896.1 - 3.2e-98 328.8 2.6 4.3e-98 328.4 2.6 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 ETS86896.1 - 7.9e-10 38.2 1.5 1.6e-08 33.8 1.5 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) BING4CT PF08149.11 ETS86898.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 BING4CT (NUC141) domain Lar_N PF09861.9 ETS86898.1 - 0.2 10.8 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Lactate racemase N-terminal domain Cyclase PF04199.13 ETS86899.1 - 6.4e-31 107.4 0.1 8.8e-31 107.0 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase HET PF06985.11 ETS86900.1 - 3.7e-24 85.7 0.1 7.1e-24 84.8 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AgrD PF05931.11 ETS86900.1 - 0.13 12.3 0.0 0.44 10.6 0.0 1.9 1 0 0 1 1 1 0 Staphylococcal AgrD protein HET PF06985.11 ETS86903.1 - 1.1e-35 123.1 0.0 3.6e-35 121.5 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 ETS86904.1 - 6.3e-60 203.2 0.0 8.4e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PQQ_3 PF13570.6 ETS86905.1 - 0.04 14.4 0.5 37 5.0 0.0 4.4 3 2 1 4 4 4 0 PQQ-like domain PQQ PF01011.21 ETS86905.1 - 0.041 13.8 0.4 9.6 6.3 0.0 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat FAD_binding_3 PF01494.19 ETS86906.1 - 2e-26 93.1 0.0 2.8e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS86906.1 - 5.6e-08 32.4 0.0 0.0023 17.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS86906.1 - 7.4e-06 26.4 0.2 0.0031 18.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ETS86906.1 - 8.8e-05 21.5 0.8 1.3 7.8 0.0 3.1 3 0 0 3 3 3 2 Tryptophan halogenase DAO PF01266.24 ETS86906.1 - 0.00017 21.3 0.1 0.0082 15.8 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS86906.1 - 0.00066 18.9 0.5 0.0038 16.4 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 ETS86906.1 - 0.00066 19.9 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS86906.1 - 0.0028 17.0 0.1 0.66 9.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ETS86906.1 - 0.0069 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA SE PF08491.10 ETS86906.1 - 0.017 14.2 0.0 0.039 13.0 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.22 ETS86906.1 - 0.023 13.8 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 ETS86906.1 - 0.034 13.5 0.4 0.065 12.6 0.1 1.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 ETS86906.1 - 0.18 11.1 0.0 0.66 9.2 0.0 1.9 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 ETS86906.1 - 0.18 10.5 0.0 0.75 8.4 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Tyrosinase PF00264.20 ETS86907.1 - 1.7e-51 175.7 0.0 2.3e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase p450 PF00067.22 ETS86908.1 - 2e-71 241.2 0.0 2.3e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.25 ETS86910.1 - 1.1e-05 25.6 0.0 1.6e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ETS86910.1 - 0.00013 22.3 0.0 0.00024 21.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS86910.1 - 0.0055 16.6 0.0 0.015 15.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETS86910.1 - 0.039 14.0 0.0 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ank_2 PF12796.7 ETS86911.1 - 2.9e-26 91.8 3.0 5.3e-10 39.7 0.1 4.1 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS86911.1 - 1e-17 62.4 0.0 0.23 12.1 0.0 9.3 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 ETS86911.1 - 6.3e-12 45.8 0.4 0.007 16.9 0.0 6.0 3 2 2 5 5 5 2 Ankyrin repeats (many copies) NACHT PF05729.12 ETS86911.1 - 7.7e-12 45.4 0.1 2.1e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 NACHT domain Ank PF00023.30 ETS86911.1 - 1.1e-10 41.4 1.3 13 6.5 0.0 8.0 8 0 0 8 8 8 0 Ankyrin repeat AAA_16 PF13191.6 ETS86911.1 - 2.3e-07 31.4 0.1 1.5e-06 28.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Ank_5 PF13857.6 ETS86911.1 - 4.6e-07 30.0 1.8 4.5 7.7 0.0 5.6 3 2 2 6 6 5 1 Ankyrin repeats (many copies) AAA_22 PF13401.6 ETS86911.1 - 0.00021 21.6 0.8 0.00056 20.2 0.0 2.2 2 0 0 2 2 1 1 AAA domain KAP_NTPase PF07693.14 ETS86911.1 - 0.00052 19.3 0.0 0.28 10.4 0.0 2.4 1 1 0 2 2 2 2 KAP family P-loop domain Syntaxin PF00804.25 ETS86911.1 - 0.013 15.1 0.8 0.013 15.1 0.8 2.7 3 0 0 3 3 3 0 Syntaxin DUF1843 PF08898.10 ETS86911.1 - 0.031 14.8 0.2 0.52 10.9 0.0 3.2 3 0 0 3 3 2 0 Domain of unknown function (DUF1843) AAA_14 PF13173.6 ETS86911.1 - 0.072 13.1 0.0 0.61 10.1 0.0 2.5 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 ETS86911.1 - 0.12 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE S_layer_N PF05123.12 ETS86911.1 - 0.4 10.5 1.3 12 5.7 0.1 3.3 2 2 2 4 4 4 0 S-layer like family, N-terminal region Filament PF00038.21 ETS86911.1 - 0.46 10.0 7.7 0.12 12.0 3.4 2.0 2 0 0 2 2 2 0 Intermediate filament protein V-SNARE PF05008.15 ETS86911.1 - 1.1 9.7 4.3 1.1 9.7 0.8 2.6 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus MnmE_helical PF12631.7 ETS86911.1 - 1.4 9.1 3.8 1.3 9.2 0.4 2.5 2 1 0 2 2 2 0 MnmE helical domain HMG_box PF00505.19 ETS86913.1 - 2.3e-25 88.8 0.9 3.2e-25 88.3 0.9 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ETS86913.1 - 1.7e-17 63.8 1.4 2.3e-17 63.3 1.4 1.2 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 ETS86913.1 - 0.0017 18.9 0.6 0.0074 16.8 0.0 1.9 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 ETS86913.1 - 0.0091 15.9 0.6 0.013 15.4 0.1 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box 5 CENP-H PF05837.12 ETS86914.1 - 1.4e-32 112.4 15.6 4.7e-31 107.5 9.4 2.0 2 0 0 2 2 2 2 Centromere protein H (CENP-H) TMCO5 PF14992.6 ETS86914.1 - 0.89 9.1 8.0 1.8 8.1 8.0 1.6 1 1 0 1 1 1 0 TMCO5 family GTA_holin_3TM PF11351.8 ETS86914.1 - 1.4 9.5 5.9 5.9 7.5 2.1 2.3 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release DUF724 PF05266.14 ETS86914.1 - 1.9 8.3 6.2 0.48 10.2 3.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4061 PF13270.6 ETS86914.1 - 2.7 8.4 7.3 1.1 9.6 2.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4061) Uso1_p115_C PF04871.13 ETS86914.1 - 3.3 8.1 12.1 0.59 10.5 5.8 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ATG11 PF10377.9 ETS86915.1 - 1.1e-42 145.1 0.1 1.1e-42 145.1 0.1 4.3 6 0 0 6 6 6 1 Autophagy-related protein 11 Cleaved_Adhesin PF07675.11 ETS86915.1 - 0.04 13.9 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Cleaved Adhesin Domain Ribosomal_L9_N PF01281.19 ETS86916.1 - 6.6e-12 44.8 0.0 1.4e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 ETS86916.1 - 0.0023 18.3 0.0 0.0082 16.6 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein L9, C-terminal domain ABC_tran PF00005.27 ETS86917.1 - 2.4e-33 115.6 0.0 6.2e-33 114.2 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ETS86917.1 - 8.4e-29 101.1 12.1 1.5e-28 100.2 12.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ETS86917.1 - 4.2e-08 32.9 2.5 3.2e-05 23.5 0.0 3.0 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ETS86917.1 - 0.0013 18.5 0.1 0.0038 16.9 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ETS86917.1 - 0.0018 18.5 0.1 0.0098 16.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain MTABC_N PF16185.5 ETS86917.1 - 0.0023 17.5 0.4 0.0023 17.5 0.4 2.9 2 1 0 2 2 2 1 Mitochondrial ABC-transporter N-terminal five TM region AAA_24 PF13479.6 ETS86917.1 - 0.0047 16.7 0.0 0.0096 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.7 ETS86917.1 - 0.015 14.3 0.0 0.031 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.6 ETS86917.1 - 0.02 15.3 2.5 0.062 13.7 0.4 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 ETS86917.1 - 0.023 14.5 0.5 0.59 9.9 0.1 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ETS86917.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 ETS86917.1 - 0.15 12.3 0.5 3.3 8.0 0.5 2.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 ETS86917.1 - 0.15 12.1 0.5 0.37 10.9 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain GWT1 PF06423.12 ETS86917.1 - 0.43 10.7 5.5 3.3 7.8 0.0 3.3 3 0 0 3 3 3 0 GWT1 Chitin_bind_1 PF00187.19 ETS86918.1 - 3.8e-08 33.7 14.9 6.4e-08 33.0 14.9 1.3 1 0 0 1 1 1 1 Chitin recognition protein DUF4983 PF16356.5 ETS86918.1 - 0.26 12.1 8.9 9.1 7.2 0.1 4.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4983) ECH_1 PF00378.20 ETS86919.1 - 6.6e-19 68.2 0.0 8.2e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ETS86919.1 - 6.2e-06 25.9 0.0 9.5e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 ETS86919.1 - 0.097 12.6 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 PGM_PMM_I PF02878.16 ETS86920.1 - 3.8e-34 117.4 0.0 5.6e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 ETS86920.1 - 4.1e-26 91.4 0.0 8e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ETS86920.1 - 9.8e-15 55.0 0.0 2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 ETS86920.1 - 2.3e-06 27.7 0.0 5.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.24 ETS86921.1 - 6e-30 105.0 0.1 6.8e-30 104.8 0.1 1.0 1 0 0 1 1 1 1 Exonuclease ERCC4 PF02732.15 ETS86922.1 - 0.087 13.0 0.1 0.14 12.4 0.1 1.5 1 1 0 1 1 1 0 ERCC4 domain Tim54 PF11711.8 ETS86923.1 - 5.5e-138 459.8 4.8 1.4e-137 458.5 4.8 1.6 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Glyco_hydro_3_C PF01915.22 ETS86924.1 - 1.7e-40 139.2 0.0 8.3e-40 136.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS86924.1 - 1e-38 133.6 0.0 1.5e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS86924.1 - 2.9e-22 78.5 0.5 7.9e-22 77.2 0.1 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain p450 PF00067.22 ETS86925.1 - 6.9e-38 130.6 0.0 8.8e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SNCAIP_SNCA_bd PF16700.5 ETS86925.1 - 0.1 12.4 0.0 2 8.2 0.1 2.5 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain Peptidase_M56 PF05569.11 ETS86926.1 - 1.7 7.8 8.8 0.25 10.5 1.2 2.3 2 0 0 2 2 2 0 BlaR1 peptidase M56 FAD_binding_4 PF01565.23 ETS86927.1 - 8.5e-26 90.4 0.0 1.5e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 ETS86927.1 - 4.7e-15 55.9 0.0 7.5e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain HET PF06985.11 ETS86928.1 - 2.6e-27 96.0 3.2 4.3e-27 95.3 3.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GST_N_3 PF13417.6 ETS86930.1 - 3.2e-09 37.1 0.1 1.1e-08 35.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ETS86930.1 - 1.3e-08 35.1 0.0 2.7e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS86930.1 - 0.0013 18.8 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2870 PF11069.8 ETS86930.1 - 0.17 12.3 0.1 0.29 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) FMO-like PF00743.19 ETS86931.1 - 1e-17 63.8 0.7 5.4e-15 54.8 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ETS86931.1 - 1.1e-11 44.6 0.0 5.5e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS86931.1 - 6.7e-09 35.3 0.1 3.2e-08 33.1 0.0 2.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ETS86931.1 - 8.1e-09 35.2 0.0 2.5e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS86931.1 - 1.7e-07 31.3 0.0 6e-06 26.4 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ETS86931.1 - 0.00047 20.7 0.0 0.53 10.9 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS86931.1 - 0.01 15.8 2.7 20 5.2 0.0 4.2 4 0 0 4 4 4 0 FAD-NAD(P)-binding HI0933_like PF03486.14 ETS86931.1 - 0.016 14.0 0.6 0.088 11.5 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 ETS86931.1 - 0.016 14.3 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 ETS86931.1 - 0.016 14.8 0.1 0.21 11.1 0.0 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ETS86931.1 - 0.14 11.2 0.1 0.41 9.7 0.1 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein CAP PF00188.26 ETS86932.1 - 9.8e-10 39.3 0.6 1.5e-09 38.8 0.6 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Ank_4 PF13637.6 ETS86934.1 - 3.2e-05 24.4 0.1 0.59 10.8 0.0 4.9 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS86934.1 - 6.7e-05 23.4 0.1 0.78 10.4 0.0 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS86934.1 - 0.0016 18.8 3.4 36 5.4 0.0 6.1 7 0 0 7 7 7 1 Ankyrin repeat F-box PF00646.33 ETS86934.1 - 0.13 12.2 1.5 0.33 10.9 0.0 2.4 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 ETS86934.1 - 0.28 11.1 2.6 0.36 10.7 0.1 2.5 3 0 0 3 3 3 0 F-box-like Methyltransf_2 PF00891.18 ETS86935.1 - 1.1e-19 70.5 0.0 1.7e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 ETS86935.1 - 0.015 16.0 0.0 0.058 14.1 0.0 2.0 3 0 0 3 3 3 0 Methyltransferase domain p450 PF00067.22 ETS86936.1 - 4.5e-49 167.4 0.0 1.2e-48 166.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 ETS86940.1 - 2.4e-17 62.9 8.4 1.1e-12 47.6 6.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ETS86940.1 - 3.2e-06 26.3 17.1 3.3e-05 23.0 16.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 ETS86941.1 - 5.9e-35 120.5 0.0 8e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS86941.1 - 1.6e-24 86.8 0.0 2e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 ETS86941.1 - 5.4e-09 35.8 0.0 0.00013 21.4 0.0 2.1 1 1 1 2 2 2 2 Fungal family of unknown function (DUF1776) KR PF08659.10 ETS86941.1 - 7.2e-09 35.8 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ETS86941.1 - 1.9e-06 27.9 0.2 5.4e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 ETS86941.1 - 0.022 14.2 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ETS86941.1 - 0.044 13.3 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family F420_oxidored PF03807.17 ETS86941.1 - 0.051 14.2 0.0 0.13 12.9 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Asparaginase_C PF17763.1 ETS86941.1 - 0.083 13.1 0.1 0.23 11.7 0.1 1.7 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain YchF-GTPase_C PF06071.13 ETS86943.1 - 1.6e-33 114.7 0.8 4.7e-33 113.2 0.1 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 ETS86943.1 - 1.7e-16 60.3 0.0 3.6e-16 59.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ETS86943.1 - 0.00046 19.8 0.0 0.00082 18.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 ETS86943.1 - 0.003 17.6 0.0 0.007 16.4 0.0 1.6 1 0 0 1 1 1 1 TGS domain PPAK PF02818.15 ETS86943.1 - 0.076 13.2 2.9 0.23 11.6 2.9 1.8 1 0 0 1 1 1 0 PPAK motif AAA_14 PF13173.6 ETS86943.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ETS86943.1 - 0.95 9.9 5.8 27 5.2 5.8 2.4 1 1 0 1 1 1 0 AAA domain Peptidase_C97 PF05903.14 ETS86944.1 - 3.4e-36 124.3 0.0 4.2e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 ETS86944.1 - 0.021 15.1 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Ribosomal_S11 PF00411.19 ETS86945.1 - 2.3e-10 40.8 0.0 6.2e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S11 Tim44 PF04280.15 ETS86946.1 - 3.2e-36 124.6 0.0 2.5e-35 121.7 0.0 2.1 2 0 0 2 2 2 1 Tim44-like domain DUF3391 PF11871.8 ETS86946.1 - 1.7 9.2 9.7 1.2 9.7 6.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Med7 PF05983.11 ETS86946.1 - 8.3 6.4 11.6 2.1 8.4 7.9 1.9 2 1 0 2 2 2 0 MED7 protein DUF1768 PF08719.11 ETS86947.1 - 3.4e-52 176.9 0.0 4.5e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) NST1 PF13945.6 ETS86947.1 - 1.1 9.4 5.2 1.8 8.6 5.2 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Chromo_2 PF18704.1 ETS86948.1 - 0.023 14.9 0.0 0.039 14.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin organization modifier domain 2 7TMR-HDED PF07697.11 ETS86949.1 - 0.025 14.7 0.0 11 6.1 0.0 2.9 2 1 1 3 3 3 0 7TM-HD extracellular Sugar_tr PF00083.24 ETS86950.1 - 1.2e-69 235.4 32.6 1.4e-69 235.2 32.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS86950.1 - 7.6e-24 84.3 61.4 7e-22 77.8 33.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS86950.1 - 1.2e-05 24.1 37.9 0.00017 20.3 13.3 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 ETS86950.1 - 8.2 5.2 23.0 1 8.2 4.8 2.6 1 1 2 3 3 3 0 MFS_1 like family Glyco_hydro_3_C PF01915.22 ETS86951.1 - 9.6e-58 195.5 0.0 1.5e-57 194.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ETS86951.1 - 4.3e-36 124.9 0.0 1e-35 123.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ETS86951.1 - 1.7e-23 82.5 0.3 3.8e-23 81.4 0.3 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 ETS86951.1 - 8.4e-08 32.1 0.0 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 PA14 domain DUF2188 PF09954.9 ETS86951.1 - 0.0069 16.5 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2188) PKD PF00801.20 ETS86951.1 - 0.016 15.0 0.0 0.057 13.3 0.0 2.0 1 0 0 1 1 1 0 PKD domain hnRNP_Q_AcD PF18360.1 ETS86951.1 - 0.17 11.9 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Methyltransf_23 PF13489.6 ETS86953.1 - 2.8e-12 46.8 0.0 3.9e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS86953.1 - 5.2e-12 46.3 0.1 2.4e-11 44.1 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS86953.1 - 5.8e-12 46.2 0.1 5.3e-11 43.1 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS86953.1 - 3.8e-11 43.6 0.0 2e-10 41.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS86953.1 - 5.7e-09 35.9 0.0 1.2e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ETS86953.1 - 4.3e-05 22.9 0.0 0.00052 19.4 0.0 2.1 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 ETS86953.1 - 0.00014 21.2 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ETS86953.1 - 0.0011 18.5 0.0 0.0024 17.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 ETS86953.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_33 PF10017.9 ETS86953.1 - 0.022 13.9 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_5 PF01795.19 ETS86953.1 - 0.055 13.0 0.0 4.8 6.6 0.0 2.1 2 0 0 2 2 2 0 MraW methylase family Methyltransf_9 PF08003.11 ETS86953.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 ETS86953.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 ETS86954.1 - 6.5e-19 68.4 0.0 1.3e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS86954.1 - 3.5e-18 66.1 0.0 6.8e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS86954.1 - 3.8e-18 65.7 0.0 5.5e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS86954.1 - 3e-16 59.7 0.0 4.4e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ETS86954.1 - 5.9e-11 42.2 0.0 6.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 ETS86954.1 - 5.9e-11 42.1 0.0 4.5e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ETS86954.1 - 6.2e-11 42.9 0.0 1.2e-10 42.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ETS86954.1 - 5.3e-06 26.2 0.0 1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 ETS86954.1 - 3.8e-05 23.7 0.0 5.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS86954.1 - 6.5e-05 22.5 0.0 9.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 ETS86954.1 - 0.00016 21.5 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 ETS86954.1 - 0.0002 20.4 0.0 0.00029 19.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_PK PF05891.12 ETS86954.1 - 0.005 16.4 0.0 0.0099 15.4 0.0 1.3 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase NodS PF05401.11 ETS86954.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) PrmA PF06325.13 ETS86954.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ADH_zinc_N PF00107.26 ETS86954.1 - 0.033 14.2 0.0 0.12 12.4 0.0 1.9 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_18 PF12847.7 ETS86954.1 - 0.046 13.7 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 ETS86954.1 - 0.071 12.8 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_29 PF03141.16 ETS86954.1 - 0.14 10.7 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Nefa_Nip30_N PF10187.9 ETS86956.1 - 9.8e-28 96.6 9.9 9.8e-28 96.6 9.9 1.7 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 IHABP4_N PF16174.5 ETS86956.1 - 0.0095 16.6 11.0 0.0095 16.6 11.0 2.3 1 1 1 2 2 2 1 Intracellular hyaluronan-binding protein 4 N-terminal DUF572 PF04502.13 ETS86956.1 - 0.037 13.6 15.3 0.04 13.5 14.5 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF572) Bud13 PF09736.9 ETS86956.1 - 6.2 7.2 18.5 8.9 6.7 13.3 2.2 1 1 1 2 2 2 0 Pre-mRNA-splicing factor of RES complex Ank_2 PF12796.7 ETS86957.1 - 4e-51 171.5 7.0 3.1e-14 53.3 0.2 5.1 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS86957.1 - 4.3e-48 161.1 11.6 1.5e-09 38.2 0.0 8.5 3 2 7 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS86957.1 - 1.6e-37 123.2 4.8 0.0034 17.8 0.0 11.4 11 0 0 11 11 11 9 Ankyrin repeat HET PF06985.11 ETS86957.1 - 6.4e-37 127.1 0.0 1.7e-36 125.8 0.1 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Ank_5 PF13857.6 ETS86957.1 - 2.1e-24 85.3 11.9 0.00013 22.2 0.1 8.6 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 ETS86957.1 - 5.6e-23 80.3 14.9 0.046 14.2 0.1 10.0 9 0 0 9 9 9 7 Ankyrin repeat CHAP PF05257.16 ETS86957.1 - 0.0028 18.2 6.4 9.5 6.9 0.1 6.4 2 1 4 6 6 6 1 CHAP domain DUF4871 PF16167.5 ETS86957.1 - 0.046 13.7 0.0 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4871) HET PF06985.11 ETS86958.1 - 9.5e-25 87.7 0.0 1.4e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 ETS86960.1 - 3.5e-34 117.2 4.5 2.8e-08 34.3 0.1 9.3 3 3 7 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS86960.1 - 1.6e-30 105.1 6.4 5e-06 27.0 0.0 10.1 7 1 2 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS86960.1 - 1.3e-21 74.3 10.9 5e-05 23.4 0.0 13.3 13 0 0 13 13 13 4 Ankyrin repeat Ank_5 PF13857.6 ETS86960.1 - 7.9e-14 51.5 6.4 0.17 12.2 0.1 8.4 7 2 1 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 ETS86960.1 - 2.6e-11 43.4 21.3 0.022 15.2 0.1 11.3 14 0 0 14 14 14 3 Ankyrin repeat RraA-like PF03737.15 ETS86961.1 - 9.5e-32 110.2 0.0 1.7e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 Aldolase/RraA SGL PF08450.12 ETS86961.1 - 1.9e-12 47.3 0.1 4.6e-12 46.0 0.1 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Amidohydro_2 PF04909.14 ETS86962.1 - 5.3e-20 72.4 0.1 7.9e-20 71.8 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase Mycobact_memb PF05423.13 ETS86962.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Mycobacterium membrane protein Mito_carr PF00153.27 ETS86963.1 - 2.2e-47 158.9 4.2 8e-17 61.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 ETS86963.1 - 0.0075 16.3 7.2 2.4 8.3 0.1 3.4 3 0 0 3 3 3 2 Pre-toxin domain with VENN motif Zn_clus PF00172.18 ETS86964.1 - 1.1e-09 38.2 8.9 1.9e-09 37.5 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS86964.1 - 1.2e-09 37.7 0.2 3.4e-09 36.1 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aconitase PF00330.20 ETS86965.1 - 2e-135 452.4 0.0 2.7e-135 452.0 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ETS86965.1 - 6.2e-36 123.6 0.0 1.2e-35 122.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 ETS86965.1 - 0.032 13.0 0.0 0.059 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Mu-like_Com PF10122.9 ETS86965.1 - 0.16 11.5 0.3 1.6 8.3 0.1 2.3 2 0 0 2 2 2 0 Mu-like prophage protein Com MFS_1 PF07690.16 ETS86966.1 - 3.4e-38 131.5 19.8 3.4e-38 131.5 19.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily HATPase_c PF02518.26 ETS86967.1 - 8.8e-22 77.7 0.1 2.1e-21 76.5 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ETS86967.1 - 8.4e-18 64.6 0.0 2.1e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ETS86967.1 - 4.1e-12 46.0 0.4 1.2e-11 44.4 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 ETS86967.1 - 0.067 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain MIG-14_Wnt-bd PF06664.12 ETS86970.1 - 0.0043 16.3 1.5 0.0054 16.0 0.5 1.6 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Deltameth_res PF16020.5 ETS86970.1 - 0.089 12.7 0.4 0.22 11.4 0.4 1.6 1 0 0 1 1 1 0 Deltamethrin resistance SUR7 PF06687.12 ETS86971.1 - 0.019 14.6 7.7 0.13 11.9 7.7 1.9 1 1 0 1 1 1 0 SUR7/PalI family MHYT PF03707.16 ETS86971.1 - 0.13 12.4 7.0 0.24 11.6 1.3 2.6 2 1 0 2 2 2 0 Bacterial signalling protein N terminal repeat Pilin_N PF07790.11 ETS86971.1 - 0.49 11.4 4.0 3.7 8.6 0.6 2.3 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal Lig_chan PF00060.26 ETS86971.1 - 1.9 8.3 6.9 3.2 7.6 6.9 1.4 1 1 0 1 1 1 0 Ligand-gated ion channel FAD_binding_4 PF01565.23 ETS86972.1 - 1.1e-21 77.0 1.1 1.4e-21 76.7 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain Fungal_trans_2 PF11951.8 ETS86973.1 - 8.5e-06 24.8 0.3 1.2e-05 24.3 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3808 PF10300.9 ETS86973.1 - 0.034 12.9 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Sulfatase PF00884.23 ETS86975.1 - 1.8e-64 218.1 2.6 2.4e-64 217.7 2.6 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 ETS86975.1 - 0.00038 20.1 1.5 0.046 13.3 0.5 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.16 ETS86976.1 - 2.5e-42 145.1 49.8 7.8e-40 136.9 49.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 ETS86976.1 - 2.3e-05 23.0 11.4 4.6e-05 22.0 11.4 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector DUF5070 PF16802.5 ETS86976.1 - 0.025 14.6 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5070) Zip PF02535.22 ETS86976.1 - 0.049 12.8 0.1 0.049 12.8 0.1 2.6 3 0 0 3 3 3 0 ZIP Zinc transporter Fungal_trans PF04082.18 ETS86977.1 - 1.3e-16 60.4 0.4 2e-16 59.9 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS86977.1 - 0.00012 22.1 11.1 0.00025 21.1 11.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ETS86978.1 - 4.5e-26 91.6 28.6 4.5e-26 91.6 28.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3522 PF12036.8 ETS86978.1 - 0.42 10.9 5.8 1.2 9.4 0.4 3.4 3 2 0 3 3 3 0 Protein of unknown function (DUF3522) Fungal_trans PF04082.18 ETS86979.1 - 7.2e-20 71.1 2.1 1.8e-19 69.8 2.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS86979.1 - 7.8e-06 25.9 5.0 1.4e-05 25.1 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glycos_trans_3N PF02885.17 ETS86979.1 - 0.028 14.3 0.3 0.064 13.1 0.3 1.5 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain Amidase PF01425.21 ETS86980.1 - 1.2e-87 294.8 0.1 1.9e-87 294.1 0.1 1.3 1 0 0 1 1 1 1 Amidase CT_A_B PF02626.15 ETS86980.1 - 4.6e-86 288.7 0.0 7.9e-86 287.9 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 ETS86980.1 - 8.3e-63 211.7 0.1 1.5e-62 210.9 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ETS86980.1 - 2.2e-40 137.6 0.1 1.2e-39 135.3 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain CT_C_D PF02682.16 ETS86980.1 - 5.3e-34 117.7 0.0 1.7e-33 116.1 0.0 1.8 2 0 0 2 2 2 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 ETS86980.1 - 4e-33 113.7 0.0 8.3e-33 112.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 ETS86980.1 - 4.2e-13 49.3 0.0 7.9e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.22 ETS86980.1 - 3.2e-12 46.1 0.2 8.2e-12 44.8 0.2 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ETS86980.1 - 2.5e-06 27.2 0.0 0.0037 17.1 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 ETS86980.1 - 0.00049 19.4 0.1 0.1 11.8 0.0 3.0 2 1 1 3 3 3 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 ETS86980.1 - 0.0005 20.7 0.1 0.068 13.9 0.1 2.7 1 1 1 2 2 2 1 HlyD family secretion protein RimK PF08443.11 ETS86980.1 - 0.0044 16.6 0.0 0.0081 15.8 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain WSC PF01822.19 ETS86981.1 - 2.7e-56 187.7 121.0 4.3e-19 68.5 16.7 8.8 8 1 1 9 9 9 5 WSC domain PAN_4 PF14295.6 ETS86981.1 - 2.2e-11 43.5 12.8 7.3e-06 25.8 0.5 8.5 9 0 0 9 9 9 3 PAN domain PAN_1 PF00024.26 ETS86981.1 - 0.00049 20.0 1.3 0.00049 20.0 1.3 9.1 8 3 1 10 10 10 3 PAN domain PAN_3 PF08277.12 ETS86981.1 - 0.0042 16.9 2.1 0.0042 16.9 2.1 7.3 8 0 0 8 8 8 3 PAN-like domain Hydrolase_4 PF12146.8 ETS86981.1 - 0.033 13.4 0.0 0.29 10.4 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 ETS86981.1 - 0.033 13.9 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Zn_Tnp_IS1 PF03811.13 ETS86981.1 - 3.7 7.3 5.8 51 3.7 0.0 3.8 4 0 0 4 4 4 0 InsA N-terminal domain Aa_trans PF01490.18 ETS86982.1 - 1.1e-59 202.2 35.2 1.3e-59 202.0 35.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3852 PF12963.7 ETS86982.1 - 0.048 14.0 0.1 0.048 14.0 0.1 3.5 4 1 1 5 5 5 0 Protein of unknown function (DUF3852) Oxidored_q3 PF00499.20 ETS86983.1 - 0.0022 17.7 0.0 0.003 17.3 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Saf_2TM PF18303.1 ETS86983.1 - 0.0031 17.1 0.1 0.0047 16.5 0.1 1.3 1 0 0 1 1 1 1 SAVED-fused 2TM effector domain DUF1282 PF06930.12 ETS86983.1 - 0.019 14.7 0.3 0.028 14.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) SLATT_5 PF18160.1 ETS86983.1 - 0.022 14.1 0.4 0.038 13.3 0.0 1.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF1980 PF09323.10 ETS86983.1 - 0.068 13.1 0.1 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) E1-E2_ATPase PF00122.20 ETS86983.1 - 0.092 12.3 1.2 2.8 7.4 1.8 2.2 1 1 1 2 2 2 0 E1-E2 ATPase CorA PF01544.18 ETS86983.1 - 0.18 11.1 4.4 0.56 9.5 4.4 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.25 ETS86984.1 - 2e-34 119.2 0.0 3.4e-29 102.0 0.0 3.3 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS86984.1 - 3.6e-22 78.9 0.0 4.7e-21 75.2 0.0 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 ETS86984.1 - 0.0016 18.5 0.1 0.014 15.3 0.1 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETS86984.1 - 0.002 17.8 0.1 0.02 14.5 0.0 2.4 1 1 0 2 2 2 1 Choline/ethanolamine kinase TPR_10 PF13374.6 ETS86985.1 - 6.9e-56 184.7 8.8 8.3e-09 35.0 0.0 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 ETS86985.1 - 5.5e-49 164.4 22.9 8.2e-11 42.1 0.1 7.8 2 1 6 8 8 8 8 Tetratricopeptide repeat Pkinase PF00069.25 ETS86985.1 - 2.7e-20 72.8 0.0 6.6e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS86985.1 - 1.2e-15 57.5 0.0 3.9e-15 55.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_7 PF13176.6 ETS86985.1 - 4.2e-10 38.9 7.1 0.55 10.4 0.1 7.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 ETS86985.1 - 8.1e-10 38.6 10.0 2.4e-05 23.9 0.4 3.1 1 1 2 3 3 3 3 MalT-like TPR region TPR_2 PF07719.17 ETS86985.1 - 2.9e-08 33.2 9.0 1 9.6 0.4 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS86985.1 - 3.1e-08 34.0 2.9 0.044 14.3 0.0 5.1 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 ETS86985.1 - 2.6e-06 27.0 5.9 1.2 9.1 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 ETS86985.1 - 7.4e-06 25.8 7.7 0.41 11.0 0.2 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ETS86985.1 - 1.3e-05 25.8 1.1 1.1 10.0 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 ETS86985.1 - 1.5e-05 25.2 6.5 0.75 10.6 0.1 6.2 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_5 PF12688.7 ETS86985.1 - 0.00031 20.9 1.9 0.063 13.5 0.1 3.7 3 1 0 3 3 3 1 Tetratrico peptide repeat TPR_14 PF13428.6 ETS86985.1 - 0.00092 19.8 7.5 12 7.0 0.0 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS86985.1 - 0.0012 19.1 0.1 19 5.6 0.0 4.2 3 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Kdo PF06293.14 ETS86985.1 - 0.0046 16.4 0.1 0.016 14.6 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_11 PF13414.6 ETS86985.1 - 0.048 13.3 4.8 5.4 6.8 0.3 4.4 5 0 0 5 5 5 0 TPR repeat TPR_17 PF13431.6 ETS86985.1 - 0.12 12.9 1.3 1.3e+02 3.3 0.1 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_transf_25 PF01755.17 ETS86986.1 - 0.0036 17.2 0.2 0.024 14.5 0.2 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Podoplanin PF05808.11 ETS86987.1 - 0.00014 22.0 4.0 0.00014 22.0 4.0 1.7 2 0 0 2 2 2 1 Podoplanin PTP_tm PF18861.1 ETS86987.1 - 0.015 15.3 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Yip1 PF04893.17 ETS86987.1 - 0.016 15.0 0.5 0.029 14.1 0.5 1.4 1 0 0 1 1 1 0 Yip1 domain Gram_pos_anchor PF00746.21 ETS86987.1 - 0.043 13.8 0.6 0.11 12.5 0.6 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif TraL PF07178.11 ETS86987.1 - 0.08 13.4 0.2 0.18 12.3 0.2 1.5 1 0 0 1 1 1 0 TraL protein Phage_Coat_B PF05356.11 ETS86987.1 - 4 7.4 7.7 1.2 9.1 2.6 2.4 1 1 1 2 2 2 0 Phage Coat protein B HET PF06985.11 ETS86990.1 - 1.6e-25 90.1 0.1 4.3e-25 88.8 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF1765 PF08578.10 ETS86994.1 - 7.2e-43 146.0 3.5 1.3e-42 145.2 3.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Brix PF04427.18 ETS86995.1 - 8e-42 143.5 0.1 1.1e-41 143.1 0.1 1.2 1 0 0 1 1 1 1 Brix domain DUF1772 PF08592.11 ETS86996.1 - 1.9e-06 28.2 2.8 1e-05 25.8 2.8 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) MscS_TM PF12794.7 ETS86996.1 - 0.08 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 adh_short_C2 PF13561.6 ETS86997.1 - 1.9e-37 129.1 0.3 2.8e-37 128.5 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS86997.1 - 5.2e-31 107.6 0.3 7.5e-31 107.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS86997.1 - 7.8e-09 35.7 1.1 2e-07 31.1 0.1 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 ETS86997.1 - 0.026 14.0 0.3 0.11 11.9 0.3 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS86997.1 - 0.044 13.2 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ETS86997.1 - 0.063 12.4 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 ETS86998.1 - 3e-41 141.0 0.2 7.2e-41 139.8 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS86998.1 - 2.2e-30 105.9 0.0 3e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS86998.1 - 6.2e-11 42.5 1.9 7.9e-10 38.9 1.9 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS86998.1 - 4.2e-07 29.7 0.2 1.5e-06 27.8 0.0 2.0 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS86998.1 - 0.0005 20.0 0.1 0.0011 18.9 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ETS86998.1 - 0.0016 17.9 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase UPF0146 PF03686.13 ETS86998.1 - 0.0089 15.9 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) RmlD_sub_bind PF04321.17 ETS86998.1 - 0.022 13.9 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 ETS86998.1 - 0.027 13.5 0.1 0.037 13.0 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 ETS86998.1 - 0.046 13.6 0.2 0.071 13.0 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3216 PF11505.8 ETS86998.1 - 0.093 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) TrkA_N PF02254.18 ETS86998.1 - 0.094 13.0 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.15 ETS86998.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 ETS86998.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ETS86998.1 - 0.27 10.8 1.6 0.52 9.8 1.3 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Indigoidine_A PF04227.12 ETS87001.1 - 3.5e-108 361.4 0.1 5.9e-108 360.6 0.1 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 ETS87001.1 - 8.2e-26 91.0 0.1 1.2e-16 60.9 0.0 3.0 2 1 0 2 2 2 2 pfkB family carbohydrate kinase WD40 PF00400.32 ETS87002.1 - 4.4e-08 33.7 0.2 2.5 9.1 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS87002.1 - 3.7e-05 23.9 0.0 0.8 10.0 0.0 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 ETS87002.1 - 0.099 12.6 0.5 0.44 10.5 0.0 2.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PDZ_4 PF17816.1 ETS87003.1 - 0.11 12.8 0.0 0.24 11.8 0.0 1.6 1 1 0 1 1 1 0 PDZ domain AICARFT_IMPCHas PF01808.18 ETS87004.1 - 1.3e-92 310.4 0.0 1.8e-92 309.9 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 ETS87004.1 - 8e-24 83.7 0.0 1.5e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Sld5 PF05916.11 ETS87005.1 - 1.8e-12 47.7 0.0 2.6e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein R-HINP1I PF11463.8 ETS87005.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease Sulfate_transp PF00916.20 ETS87006.1 - 2.3e-54 184.6 14.7 3.6e-54 184.0 14.7 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 ETS87006.1 - 1.9e-18 66.3 0.0 6.6e-18 64.6 0.0 2.0 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain STAS PF01740.21 ETS87006.1 - 5.8e-09 35.6 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain GST_C PF00043.25 ETS87007.1 - 6.7e-05 23.0 0.1 0.00014 22.0 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ETS87007.1 - 0.0007 19.7 0.0 0.0021 18.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Terminase_6C PF17289.2 ETS87007.1 - 0.09 12.9 0.0 0.12 12.4 0.0 1.3 1 1 0 1 1 1 0 Terminase RNaseH-like domain MFS_1 PF07690.16 ETS87008.1 - 8.1e-48 163.1 21.2 8.1e-48 163.1 21.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS87008.1 - 2.2e-11 43.3 6.9 2.2e-11 43.3 6.9 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 ETS87008.1 - 0.035 12.4 6.9 0.012 13.9 2.6 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SAYSvFN PF10260.9 ETS87008.1 - 0.19 11.6 1.8 0.57 10.1 0.5 2.5 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) MerC PF03203.14 ETS87009.1 - 0.039 14.4 1.9 0.055 13.9 1.9 1.2 1 0 0 1 1 1 0 MerC mercury resistance protein PLAC9 PF15205.6 ETS87011.1 - 0.0071 16.7 0.1 0.042 14.3 0.1 2.4 1 0 0 1 1 1 1 Placenta-specific protein 9 Filament PF00038.21 ETS87011.1 - 0.0071 16.0 12.4 0.0071 16.0 12.4 6.3 4 2 0 4 4 4 3 Intermediate filament protein EspB_PE PF18625.1 ETS87011.1 - 0.12 12.9 7.9 0.066 13.7 2.9 3.4 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain Baculo_PEP_C PF04513.12 ETS87011.1 - 1.5 8.8 29.7 0.34 11.0 2.6 6.0 5 1 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Shugoshin_N PF07558.11 ETS87011.1 - 2.5 8.0 10.7 6.9 6.6 0.2 5.1 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region Dynein_attach_N PF15867.5 ETS87011.1 - 2.9 7.9 7.2 3.2 7.8 2.4 3.2 2 0 0 2 2 2 0 Dynein attachment factor N-terminus ATG16 PF08614.11 ETS87011.1 - 4 7.6 93.7 1.8 8.7 0.7 6.9 4 1 1 5 5 5 0 Autophagy protein 16 (ATG16) Hydantoinase_B PF02538.14 ETS87012.1 - 9.3e-128 426.9 0.0 1.4e-127 426.3 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 ETS87012.1 - 1.6e-94 316.4 5.7 1e-93 313.8 2.1 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ETS87012.1 - 3.7e-48 163.6 0.2 1.6e-45 155.0 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 ETS87012.1 - 0.00074 18.2 2.8 0.071 11.7 0.4 2.3 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 ETS87012.1 - 0.011 15.2 0.7 0.46 9.9 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DEDD_Tnp_IS110 PF01548.17 ETS87012.1 - 0.2 11.5 0.0 0.5 10.2 0.0 1.7 1 0 0 1 1 1 0 Transposase DUF3871 PF12987.7 ETS87012.1 - 0.24 10.2 0.0 0.52 9.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3871) TMEM154 PF15102.6 ETS87013.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family UPF0370 PF13980.6 ETS87013.1 - 0.37 10.9 5.7 0.56 10.3 5.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) hDGE_amylase PF14701.6 ETS87015.1 - 7.4e-178 592.1 0.0 9.5e-178 591.8 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 ETS87015.1 - 6.4e-120 400.6 0.3 1.4e-119 399.4 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 ETS87015.1 - 1.8e-87 293.2 0.0 5.4e-87 291.6 0.0 1.8 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 ETS87015.1 - 6.1e-30 103.2 0.0 1.4e-29 102.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme 2-Hacid_dh PF00389.30 ETS87015.1 - 0.11 12.2 0.0 0.42 10.3 0.0 2.0 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_Gly3P_dh_N PF01210.23 ETS87016.1 - 2.8e-45 154.1 0.1 8.6e-45 152.5 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 ETS87016.1 - 1.6e-42 145.1 0.2 2.5e-42 144.5 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus AIG2_2 PF13772.6 ETS87017.1 - 0.0066 16.8 0.0 0.098 13.1 0.0 2.2 2 0 0 2 2 2 1 AIG2-like family TPP_enzyme_N PF02776.18 ETS87018.1 - 3e-53 179.9 0.1 1.3e-52 177.8 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ETS87018.1 - 1.8e-49 167.4 0.5 4.2e-48 163.0 0.1 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ETS87018.1 - 5.4e-40 136.3 0.5 1.8e-39 134.6 0.2 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain NeA_P2 PF12312.8 ETS87019.1 - 0.013 15.0 1.0 0.013 15.0 1.0 1.7 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein Inhibitor_I66 PF16850.5 ETS87019.1 - 0.13 12.1 0.7 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Peptidase inhibitor I66 Carb_kinase PF01256.17 ETS87020.1 - 5.9e-57 192.9 0.1 7.3e-57 192.6 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 ETS87020.1 - 0.0039 16.6 0.0 0.0082 15.5 0.0 1.5 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 ETS87020.1 - 0.044 13.2 0.0 0.075 12.4 0.0 1.5 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase ATP-synt_ab PF00006.25 ETS87021.1 - 6e-73 245.0 0.0 8.8e-73 244.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 ETS87021.1 - 1e-47 161.6 0.6 1.8e-47 160.8 0.6 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 ETS87021.1 - 3.5e-15 56.3 2.8 8.5e-15 55.0 2.8 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Rax2 PF12768.7 ETS87022.1 - 0.026 14.0 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.10 ETS87022.1 - 0.035 13.5 0.6 0.11 11.9 0.6 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Copper-fist PF00649.18 ETS87022.1 - 0.2 11.2 0.5 0.44 10.1 0.5 1.5 1 0 0 1 1 1 0 Copper fist DNA binding domain Proteasom_Rpn13 PF04683.13 ETS87024.1 - 7.1e-27 93.8 0.0 1.1e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 ETS87024.1 - 4.6e-09 36.4 3.0 4e-08 33.4 3.0 2.2 1 1 0 1 1 1 1 UCH-binding domain Ribosomal_L6e PF01159.19 ETS87025.1 - 3.8e-39 133.7 0.2 3.8e-39 133.7 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e Peptidase_M49 PF03571.15 ETS87026.1 - 1.1e-243 809.7 0.0 1.3e-243 809.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 2C_adapt PF08793.10 ETS87026.1 - 0.26 11.5 0.9 0.54 10.5 0.9 1.5 1 0 0 1 1 1 0 2-cysteine adaptor domain SKI PF01202.22 ETS87027.1 - 8.8e-12 45.4 0.0 1.4e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 ETS87027.1 - 1.2e-10 41.7 0.0 2.2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETS87027.1 - 9.4e-10 39.1 0.0 4.2e-09 37.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ETS87027.1 - 1.2e-06 29.0 0.1 1.2e-05 25.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 ETS87027.1 - 7.9e-06 25.9 0.0 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 ETS87027.1 - 1.9e-05 24.5 0.1 3.5e-05 23.6 0.0 1.5 2 0 0 2 2 1 1 Cytidylate kinase AAA_16 PF13191.6 ETS87027.1 - 0.00038 20.9 0.0 0.00079 19.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain dNK PF01712.19 ETS87027.1 - 0.00097 19.0 0.0 0.083 12.7 0.0 2.5 2 1 0 2 2 2 1 Deoxynucleoside kinase AAA_28 PF13521.6 ETS87027.1 - 0.0011 19.3 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ETS87027.1 - 0.0015 18.5 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ETS87027.1 - 0.0016 18.7 0.0 0.0047 17.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 ETS87027.1 - 0.0024 17.3 0.1 0.0058 16.0 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 ETS87027.1 - 0.003 18.0 0.1 0.025 15.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ETS87027.1 - 0.004 16.9 0.5 0.0086 15.8 0.1 1.6 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 ETS87027.1 - 0.0081 16.3 0.5 0.15 12.1 0.0 2.6 2 1 1 3 3 2 1 Cytidylate kinase-like family NACHT PF05729.12 ETS87027.1 - 0.0089 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 ETS87027.1 - 0.0094 16.3 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 ETS87027.1 - 0.012 16.1 0.0 0.03 14.8 0.0 1.7 2 0 0 2 2 2 0 ABC transporter APS_kinase PF01583.20 ETS87027.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.4 1 1 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.15 ETS87027.1 - 0.014 15.3 0.1 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 NTPase T2SSE PF00437.20 ETS87027.1 - 0.015 14.4 0.1 0.036 13.1 0.1 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 ETS87027.1 - 0.034 14.5 0.4 0.27 11.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain CoaE PF01121.20 ETS87027.1 - 0.039 13.6 0.0 0.092 12.4 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase PRK PF00485.18 ETS87027.1 - 0.042 13.6 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 ETS87027.1 - 0.043 13.6 0.1 0.08 12.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 ETS87027.1 - 0.055 13.2 0.0 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 ETS87027.1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 ETS87027.1 - 0.063 12.5 0.1 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 ETS87027.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.5 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 ETS87027.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta2 PF13177.6 ETS87027.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit PhoH PF02562.16 ETS87027.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 ETS87027.1 - 0.19 11.8 0.0 0.45 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain 2-oxoacid_dh PF00198.23 ETS87028.1 - 2.8e-78 262.6 0.8 4.1e-78 262.0 0.8 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ETS87028.1 - 9.4e-17 60.6 0.1 1.8e-16 59.7 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 ETS87028.1 - 1.4e-12 47.7 0.0 3.5e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain ATP-synt_10 PF05176.14 ETS87029.1 - 1.2e-73 247.6 0.0 1.6e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein zf-CCHC PF00098.23 ETS87031.1 - 4.5e-05 23.3 0.9 7.3e-05 22.7 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF637 PF04830.13 ETS87031.1 - 0.014 15.2 2.2 0.02 14.7 2.2 1.2 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) RskA PF10099.9 ETS87031.1 - 0.028 14.7 2.5 0.037 14.3 2.5 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Velvet PF11754.8 ETS87031.1 - 0.04 13.9 13.8 0.044 13.7 13.8 1.1 1 0 0 1 1 1 0 Velvet factor Spt20 PF12090.8 ETS87031.1 - 0.043 13.4 48.6 0.064 12.9 48.6 1.3 1 0 0 1 1 1 0 Spt20 family DUF908 PF06012.12 ETS87031.1 - 0.046 13.1 12.3 0.051 13.0 12.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) RR_TM4-6 PF06459.12 ETS87031.1 - 0.063 13.1 32.5 0.074 12.9 32.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 ETS87031.1 - 0.1 11.5 16.0 0.14 11.1 16.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) zf-CCHC_4 PF14392.6 ETS87031.1 - 0.18 11.5 0.9 0.29 10.9 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF4045 PF13254.6 ETS87031.1 - 0.23 11.1 24.7 0.25 11.0 24.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Nop14 PF04147.12 ETS87031.1 - 0.27 9.4 32.3 0.3 9.2 32.3 1.0 1 0 0 1 1 1 0 Nop14-like family Gp_dh_N PF00044.24 ETS87031.1 - 0.27 11.6 4.5 0.23 11.8 3.4 1.5 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain ALMT PF11744.8 ETS87031.1 - 0.27 10.0 23.8 0.28 10.0 23.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter PPP4R2 PF09184.11 ETS87031.1 - 0.4 10.2 34.9 0.46 10.0 34.9 1.1 1 0 0 1 1 1 0 PPP4R2 CAC1F_C PF16885.5 ETS87031.1 - 0.47 10.1 17.9 0.53 9.9 17.9 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term CCDC71L PF15374.6 ETS87031.1 - 0.59 9.4 17.6 0.66 9.2 17.6 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L CDC27 PF09507.10 ETS87031.1 - 0.6 9.4 35.3 0.66 9.3 35.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AAA_11 PF13086.6 ETS87031.1 - 0.66 9.7 25.2 0.72 9.6 25.2 1.1 1 0 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.16 ETS87031.1 - 0.7 9.9 18.4 0.71 9.9 18.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.15 ETS87031.1 - 1 8.0 23.0 1.1 8.0 23.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GAGA_bind PF06217.12 ETS87031.1 - 1.1 9.5 21.5 1.2 9.4 21.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Smg8_Smg9 PF10220.9 ETS87031.1 - 1.4 7.2 23.1 1.3 7.2 23.1 1.0 1 0 0 1 1 1 0 Smg8_Smg9 MID_MedPIWI PF18296.1 ETS87031.1 - 1.5 8.5 19.7 1.9 8.2 19.7 1.2 1 0 0 1 1 1 0 MID domain of medPIWI DUF1501 PF07394.12 ETS87031.1 - 1.5 7.8 16.7 1.8 7.5 16.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF5349 PF17298.2 ETS87031.1 - 1.6 8.4 22.3 2.2 8.0 22.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5349) DUF2347 PF09804.9 ETS87031.1 - 1.7 8.2 12.9 2.3 7.8 12.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Sporozoite_P67 PF05642.11 ETS87031.1 - 1.7 6.6 14.1 2 6.4 14.1 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen eIF-3_zeta PF05091.12 ETS87031.1 - 2.3 7.1 29.0 2.6 6.9 29.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RNA_pol_3_Rpc31 PF11705.8 ETS87031.1 - 3.6 7.8 33.1 4.7 7.4 33.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RNA_polI_A34 PF08208.11 ETS87031.1 - 4.3 7.4 31.9 5.7 7.0 31.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Spem1 PF15670.5 ETS87031.1 - 4.9 6.7 21.3 6 6.4 21.3 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 TCP PF03634.13 ETS87031.1 - 5.3 7.6 31.6 7.1 7.2 31.6 1.2 1 0 0 1 1 1 0 TCP family transcription factor PPL5 PF18168.1 ETS87031.1 - 5.9 6.1 25.3 7.8 5.7 25.3 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Endostatin PF06482.11 ETS87031.1 - 6.1 6.2 21.2 7.7 5.9 21.2 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Cyclin_C PF02984.19 ETS87031.1 - 6.6 6.8 10.8 8.7 6.5 10.8 1.1 1 0 0 1 1 1 0 Cyclin, C-terminal domain VIR_N PF15912.5 ETS87031.1 - 8.4 5.9 27.1 10 5.6 27.1 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal AUX_IAA PF02309.16 ETS87031.1 - 8.7 6.1 17.3 10 5.9 17.3 1.2 1 0 0 1 1 1 0 AUX/IAA family adh_short PF00106.25 ETS87033.1 - 1.9e-36 125.4 1.8 2.4e-36 125.1 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS87033.1 - 7.5e-28 97.7 2.2 8.5e-28 97.5 2.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 ETS87033.1 - 4.1e-05 23.1 0.0 5.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 ETS87033.1 - 0.00016 21.6 2.0 0.00029 20.8 2.0 1.4 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 ETS87033.1 - 0.008 15.8 0.1 0.012 15.1 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.26 ETS87033.1 - 0.0092 16.0 0.2 0.017 15.1 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 ETS87033.1 - 0.07 13.4 0.2 0.78 10.0 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ETS87033.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Clusterin PF01093.17 ETS87034.1 - 0.036 13.1 0.0 0.04 13.0 0.0 1.0 1 0 0 1 1 1 0 Clusterin PAP2 PF01569.21 ETS87035.1 - 6.3e-25 87.5 9.8 1.3e-23 83.2 7.6 3.1 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 ETS87035.1 - 0.11 13.0 1.5 0.45 11.1 1.5 2.0 1 0 0 1 1 1 0 PAP2 superfamily C-terminal Polysacc_deac_1 PF01522.21 ETS87036.1 - 2.1e-27 95.5 0.0 3.3e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 ETS87036.1 - 6.6e-17 61.7 42.1 7.9e-09 35.9 20.6 2.6 2 0 0 2 2 2 2 Chitin recognition protein STT3 PF02516.14 ETS87038.1 - 6e-143 477.3 37.2 7.2e-138 460.5 35.3 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit DUF1772 PF08592.11 ETS87039.1 - 4.2e-26 91.9 1.5 5.4e-26 91.5 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Pro_racemase PF05544.11 ETS87043.1 - 3e-122 407.7 1.1 3.4e-122 407.6 1.1 1.0 1 0 0 1 1 1 1 Proline racemase Jnk-SapK_ap_N PF09744.9 ETS87044.1 - 0.0031 17.8 12.4 0.0037 17.5 12.4 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Spc7 PF08317.11 ETS87044.1 - 0.0066 15.4 9.5 0.0077 15.2 9.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Rop-like PF05082.13 ETS87044.1 - 0.022 14.6 2.9 0.022 14.6 2.9 2.4 3 0 0 3 3 3 0 Rop-like ERM PF00769.19 ETS87044.1 - 0.025 14.4 12.6 0.04 13.7 12.6 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF1202 PF06717.11 ETS87044.1 - 0.081 12.3 0.0 0.13 11.7 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1202) Prefoldin_2 PF01920.20 ETS87044.1 - 0.097 12.6 10.6 0.074 13.0 2.8 2.6 1 1 1 2 2 2 0 Prefoldin subunit Fez1 PF06818.15 ETS87044.1 - 0.11 12.9 10.8 0.14 12.6 10.8 1.1 1 0 0 1 1 1 0 Fez1 DUF724 PF05266.14 ETS87044.1 - 0.13 12.1 9.1 0.17 11.7 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Tup_N PF08581.10 ETS87044.1 - 0.14 12.5 10.0 0.059 13.7 2.9 2.4 1 1 1 2 2 2 0 Tup N-terminal Exonuc_VII_L PF02601.15 ETS87044.1 - 0.17 11.4 5.7 0.2 11.2 5.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 ETS87044.1 - 0.18 10.9 11.6 0.95 8.5 11.6 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc24 PF08286.11 ETS87044.1 - 0.3 11.3 10.4 0.42 10.9 2.7 2.5 2 1 1 3 3 2 0 Spc24 subunit of Ndc80 ATG16 PF08614.11 ETS87044.1 - 0.47 10.6 13.4 0.13 12.4 8.6 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TMPIT PF07851.13 ETS87044.1 - 0.54 9.4 7.3 0.72 9.0 7.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 ETS87044.1 - 1 9.4 7.7 0.29 11.2 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 ETS87044.1 - 1.3 9.3 8.8 14 6.0 4.7 2.4 2 1 0 2 2 2 0 ABC transporter C-terminal domain Rx_N PF18052.1 ETS87044.1 - 2 8.7 11.4 5.4 7.4 1.0 2.2 1 1 1 2 2 2 0 Rx N-terminal domain DUF16 PF01519.16 ETS87044.1 - 3.2 8.3 9.8 24 5.5 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Fzo_mitofusin PF04799.13 ETS87044.1 - 3.5 7.2 9.4 0.97 9.0 0.9 2.1 1 1 1 2 2 2 0 fzo-like conserved region KxDL PF10241.9 ETS87044.1 - 7.1 7.0 11.7 3 8.2 6.5 2.5 1 1 2 3 3 3 0 Uncharacterized conserved protein VDE PF07137.11 ETS87045.1 - 0.071 12.6 6.0 0.1 12.1 6.0 1.3 1 0 0 1 1 1 0 VDE lipocalin domain zf-Tim10_DDP PF02953.15 ETS87045.1 - 0.4 10.4 10.2 0.094 12.4 3.2 2.7 1 1 1 2 2 2 0 Tim10/DDP family zinc finger Aldolase_II PF00596.21 ETS87046.1 - 3.2e-42 144.6 0.0 4e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.18 ETS87047.1 - 9.8e-167 554.4 18.5 1.2e-166 554.1 18.5 1.1 1 0 0 1 1 1 1 Calreticulin family DUF1911 PF08929.10 ETS87047.1 - 0.038 14.8 0.0 0.15 12.9 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) Aminotran_1_2 PF00155.21 ETS87048.1 - 1.1e-17 64.2 0.0 1.5e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ETS87048.1 - 4.6e-07 29.0 0.0 1.6e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Med14 PF08638.11 ETS87050.1 - 1.8e-65 220.0 1.0 2.9e-65 219.3 0.0 1.9 3 0 0 3 3 3 1 Mediator complex subunit MED14 MFS_1 PF07690.16 ETS87052.1 - 1.6e-27 96.4 30.5 7.2e-27 94.2 30.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_16 PF00722.21 ETS87053.1 - 3.4e-42 143.9 1.9 5.2e-42 143.3 1.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Lipid_bd PF12888.7 ETS87053.1 - 0.025 15.0 0.2 0.13 12.7 0.0 2.2 2 0 0 2 2 2 0 Lipid-binding putative hydrolase LysM PF01476.20 ETS87054.1 - 4.1e-11 42.8 0.0 6.8e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 LysM domain tRNA-synt_His PF13393.6 ETS87055.1 - 1.8e-40 139.1 0.0 2.5e-34 118.9 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 ETS87055.1 - 9.9e-15 54.5 0.0 2e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ETS87055.1 - 9.5e-05 22.4 0.0 0.00028 20.9 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 ETS87055.1 - 0.0006 19.4 0.0 0.00099 18.7 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 ETS87055.1 - 0.0067 15.5 0.0 0.039 13.0 0.0 2.0 1 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) Pkinase PF00069.25 ETS87057.1 - 5.8e-69 232.4 0.0 7.9e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS87057.1 - 1.8e-34 119.2 0.1 4.4e-34 117.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS87057.1 - 6.5e-06 25.7 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ETS87057.1 - 0.0002 20.8 0.0 0.0004 19.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ETS87057.1 - 0.0033 16.3 0.0 0.0066 15.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 ETS87057.1 - 0.0086 15.6 0.1 0.073 12.6 0.1 2.5 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL UQ_con PF00179.26 ETS87058.1 - 2e-27 95.6 0.0 2.3e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ETS87058.1 - 1.4e-07 31.2 0.0 1.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 ETS87058.1 - 0.00054 19.8 0.1 0.00089 19.1 0.1 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 ETS87058.1 - 0.001 19.3 0.0 0.0021 18.4 0.0 1.5 1 1 0 1 1 1 1 RWD domain UFC1 PF08694.11 ETS87058.1 - 0.067 12.8 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Sec1 PF00995.23 ETS87059.1 - 1.5e-131 440.5 0.0 1.7e-131 440.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Peptidase_C10 PF01640.17 ETS87059.1 - 0.084 13.2 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Peptidase C10 family Amino_oxidase PF01593.24 ETS87061.1 - 1.3e-85 288.4 0.8 2.6e-84 284.1 0.8 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 ETS87061.1 - 7.3e-13 48.7 0.1 1.9e-12 47.3 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 ETS87061.1 - 1.7e-08 34.5 0.2 3.8e-08 33.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box_2 PF09011.10 ETS87061.1 - 9.6e-07 29.3 4.1 9.6e-07 29.3 4.1 2.2 2 0 0 2 2 2 1 HMG-box domain HMG_box PF00505.19 ETS87061.1 - 2.1e-06 28.1 5.7 2.1e-06 28.1 5.7 2.5 2 1 0 2 2 2 1 HMG (high mobility group) box Pyr_redox_2 PF07992.14 ETS87061.1 - 0.00033 20.0 0.1 0.017 14.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS87061.1 - 0.0019 17.9 0.1 0.0039 16.8 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS87061.1 - 0.013 15.4 0.1 0.72 9.8 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding ATP-synt PF00231.19 ETS87062.1 - 1e-78 264.9 0.2 1.2e-78 264.7 0.2 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I_N PF02919.15 ETS87063.1 - 2.4e-97 324.6 5.4 2.4e-97 324.6 5.4 2.2 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 ETS87063.1 - 2e-94 315.2 0.9 2e-94 315.2 0.9 1.8 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 ETS87063.1 - 6.9e-32 109.2 0.8 2.9e-31 107.2 0.8 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain CorA PF01544.18 ETS87064.1 - 1.5e-41 142.6 1.1 1.3e-40 139.5 1.1 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein FANCI_S4 PF14678.6 ETS87064.1 - 0.18 10.9 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 FANCI solenoid 4 CSTF2_hinge PF14327.6 ETS87065.1 - 4.5e-32 110.3 0.3 4.5e-32 110.3 0.3 1.8 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 ETS87065.1 - 6.9e-22 77.0 0.0 1e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 ETS87065.1 - 3.3e-10 39.4 9.3 3.3e-10 39.4 9.3 2.4 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 ETS87065.1 - 0.043 13.9 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Spo7_2_N PF15407.6 ETS87065.1 - 0.073 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 Band_7 PF01145.25 ETS87066.1 - 1.7e-23 83.5 1.8 2.6e-23 82.9 1.8 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family ubiquitin PF00240.23 ETS87067.1 - 8e-26 89.6 0.3 8.9e-26 89.4 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ETS87067.1 - 3.8e-14 52.3 0.2 4.2e-14 52.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ETS87067.1 - 0.00017 22.0 0.1 0.0005 20.5 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 ETS87067.1 - 0.0056 16.6 0.0 0.0067 16.3 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Elongin_A PF06881.11 ETS87068.1 - 6.9e-31 106.9 0.1 1.5e-30 105.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A SMP PF04927.12 ETS87069.1 - 1.2e-05 25.7 1.1 2.1e-05 24.9 1.1 1.4 1 0 0 1 1 1 1 Seed maturation protein SLATT_5 PF18160.1 ETS87071.1 - 0.053 12.8 0.3 0.23 10.7 0.0 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Tetraspanin PF00335.20 ETS87071.1 - 0.1 12.3 0.0 15 5.2 0.0 2.3 2 0 0 2 2 2 0 Tetraspanin family Occludin_ELL PF07303.13 ETS87071.1 - 2.9 8.7 5.7 0.74 10.6 1.3 2.3 2 1 1 3 3 3 0 Occludin homology domain Rad21_Rec8_N PF04825.13 ETS87072.1 - 4e-37 126.8 0.0 7.9e-37 125.8 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 ETS87072.1 - 8.6e-09 34.6 0.2 1.9e-08 33.4 0.2 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein E1-E2_ATPase PF00122.20 ETS87073.1 - 1.6e-47 161.4 0.3 1.6e-47 161.4 0.3 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ETS87073.1 - 7.9e-44 149.5 2.5 7.9e-44 149.5 2.5 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ETS87073.1 - 6.9e-22 78.8 2.0 4e-21 76.3 0.6 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ETS87073.1 - 1.9e-18 65.9 0.0 4e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ETS87073.1 - 5.9e-12 45.5 0.0 1.3e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ETS87073.1 - 0.00053 19.8 0.6 0.0025 17.6 0.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Virul_Fac PF10139.9 ETS87074.1 - 0.0049 15.2 2.7 0.0054 15.0 2.7 1.0 1 0 0 1 1 1 1 Putative bacterial virulence factor HeLo PF14479.6 ETS87074.1 - 0.011 15.5 0.7 0.014 15.3 0.7 1.2 1 0 0 1 1 1 0 Prion-inhibition and propagation Rsd_AlgQ PF04353.13 ETS87074.1 - 0.021 14.8 3.5 0.17 11.9 1.4 2.2 1 1 1 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ PEP-utilisers_N PF05524.13 ETS87074.1 - 0.029 14.5 1.9 0.04 14.1 1.9 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF1664 PF07889.12 ETS87074.1 - 0.28 11.2 5.2 0.26 11.3 3.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) G-patch PF01585.23 ETS87075.1 - 1.9e-06 27.6 0.0 5e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ETS87075.1 - 0.00042 20.4 0.0 0.00042 20.4 0.0 4.2 2 1 0 2 2 2 1 G-patch domain DUF2076 PF09849.9 ETS87075.1 - 0.013 15.6 9.5 0.013 15.6 9.5 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF936 PF06075.12 ETS87075.1 - 0.018 14.0 32.2 0.021 13.8 32.2 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Mitofilin PF09731.9 ETS87075.1 - 0.16 10.7 37.2 0.23 10.2 37.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Asp-B-Hydro_N PF05279.11 ETS87075.1 - 0.21 11.6 35.9 0.28 11.2 35.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Borrelia_P83 PF05262.11 ETS87075.1 - 0.65 8.4 38.9 0.79 8.1 38.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein GREB1 PF15782.5 ETS87075.1 - 1.1 6.2 31.2 1.5 5.8 31.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIF_alpha PF05793.12 ETS87075.1 - 3.2 6.2 59.4 5.1 5.6 59.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC27 PF09507.10 ETS87075.1 - 8.6 5.6 56.3 14 5.0 56.3 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Zn_clus PF00172.18 ETS87077.1 - 1.2e-06 28.5 9.5 3.1e-06 27.2 9.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HeLo PF14479.6 ETS87078.1 - 4.9e-41 140.8 0.0 4.2e-40 137.8 0.0 2.2 2 0 0 2 2 2 1 Prion-inhibition and propagation DUF1416 PF07210.12 ETS87079.1 - 0.082 12.8 0.0 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1416) Enkurin PF13864.6 ETS87079.1 - 1 9.8 6.4 8.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Calmodulin-binding DUF3632 PF12311.8 ETS87080.1 - 3.9e-08 33.9 0.3 1.3e-07 32.2 0.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) SURF4 PF02077.15 ETS87081.1 - 3e-96 322.1 6.4 3.5e-96 321.9 6.4 1.0 1 0 0 1 1 1 1 SURF4 family Halogen_Hydrol PF10112.9 ETS87081.1 - 1.6 8.7 4.4 7 6.6 1.0 2.4 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein CLLAC PF15675.5 ETS87081.1 - 7.2 6.3 9.4 0.14 11.7 0.7 2.6 3 0 0 3 3 3 0 CLLAC-motif containing domain Tyrosinase PF00264.20 ETS87082.1 - 2.5e-32 113.0 4.4 6.3e-32 111.6 4.4 1.6 1 1 0 1 1 1 1 Common central domain of tyrosinase BRO1 PF03097.18 ETS87083.1 - 8.7e-08 31.4 0.0 1.1e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain DUF5355 PF17306.2 ETS87083.1 - 0.13 11.3 0.0 1.2 8.1 0.0 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5355) Alg6_Alg8 PF03155.15 ETS87084.1 - 6.1e-129 431.1 29.4 9.2e-83 278.8 11.3 2.2 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family EpsG PF14897.6 ETS87084.1 - 6 6.1 19.9 7.7 5.7 16.7 2.3 1 1 1 2 2 2 0 EpsG family IBR PF01485.21 ETS87085.1 - 5.8e-07 29.6 22.5 2e-05 24.7 12.8 3.5 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain DUF3837 PF12939.7 ETS87085.1 - 6.1 7.3 8.7 5.9 7.3 0.7 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3837) FAA_hydrolase PF01557.18 ETS87086.1 - 1.8e-64 217.4 0.0 2.3e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GspH PF12019.8 ETS87086.1 - 0.0044 17.4 0.2 0.0069 16.8 0.2 1.3 1 0 0 1 1 1 1 Type II transport protein GspH DUF2437 PF10370.9 ETS87086.1 - 0.044 14.7 0.2 0.23 12.4 0.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF2437) Exo_endo_phos PF03372.23 ETS87087.1 - 5.8e-07 29.3 0.0 1.3e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA_22 PF13401.6 ETS87088.1 - 0.0001 22.6 0.1 0.032 14.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ETS87088.1 - 0.0015 18.4 0.1 0.0064 16.4 0.1 2.1 1 1 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 ETS87088.1 - 0.0043 16.5 2.9 0.0052 16.2 1.4 1.8 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins ABC_tran PF00005.27 ETS87088.1 - 0.0067 16.9 0.4 0.048 14.2 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 ETS87088.1 - 0.038 14.5 0.0 0.33 11.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ETS87088.1 - 0.064 13.6 0.0 0.37 11.2 0.0 2.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 ETS87088.1 - 0.078 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 ETS87088.1 - 0.11 12.9 1.7 1.5 9.2 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ETS87088.1 - 0.11 12.7 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ETS87088.1 - 0.13 12.7 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.14 ETS87088.1 - 0.16 11.2 3.0 4 6.6 0.1 2.4 2 0 0 2 2 2 0 KAP family P-loop domain NPV_P10 PF05531.12 ETS87088.1 - 0.22 12.0 2.9 33 5.0 1.3 3.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_23 PF13476.6 ETS87088.1 - 0.71 10.3 2.8 11 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain BOP1NT PF08145.12 ETS87089.1 - 2.5e-104 348.8 8.5 3.6e-104 348.3 8.5 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 ETS87089.1 - 1.9e-27 95.0 1.8 3e-09 37.3 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS87089.1 - 2.1e-09 37.5 0.0 0.00013 22.2 0.0 4.7 3 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 ETS87089.1 - 0.0023 16.4 0.0 0.19 10.0 0.0 2.1 1 1 1 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 ETS87089.1 - 0.1 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Lipase_GDSL_2 PF13472.6 ETS87090.1 - 3.4e-24 86.2 1.3 6.4e-24 85.3 1.3 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ETS87090.1 - 7.4e-07 29.3 0.0 1.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase IBN_N PF03810.19 ETS87092.1 - 0.057 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Importin-beta N-terminal domain PDDEXK_9 PF08011.11 ETS87093.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily PP2C PF00481.21 ETS87095.1 - 2.4e-57 194.5 0.0 4.5e-57 193.6 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 ETS87095.1 - 3.9e-43 145.0 53.4 7.4e-10 38.4 0.3 8.8 5 3 4 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 ETS87095.1 - 3.4e-36 122.6 63.0 4e-05 23.9 4.0 12.1 7 2 3 12 12 12 10 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 ETS87095.1 - 1.1e-28 100.2 0.0 7.1e-28 97.5 0.0 2.1 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ad_cyc_g-alpha PF08509.11 ETS87095.1 - 3.4e-21 74.7 1.1 1.2e-20 73.0 1.1 1.9 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_1 PF00560.33 ETS87095.1 - 5.3e-07 29.3 45.2 5.2 8.0 1.3 15.7 16 2 0 16 16 16 3 Leucine Rich Repeat LRR_9 PF14580.6 ETS87095.1 - 8.2e-06 25.4 18.9 0.03 13.8 0.4 4.3 2 1 2 4 4 4 3 Leucine-rich repeat LRR_5 PF13306.6 ETS87095.1 - 0.39 10.7 1.7 11 6.0 0.1 3.0 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) RTC4 PF14474.6 ETS87096.1 - 2.2e-35 121.4 0.0 4.9e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain Cul7 PF11515.8 ETS87096.1 - 0.083 13.2 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 Dynamitin PF04912.14 ETS87097.1 - 3.5e-99 332.8 5.5 4.4e-99 332.4 5.5 1.1 1 0 0 1 1 1 1 Dynamitin Laminin_II PF06009.12 ETS87097.1 - 0.0015 18.5 9.9 0.31 11.1 0.3 4.2 2 1 2 4 4 4 1 Laminin Domain II YkyA PF10368.9 ETS87097.1 - 0.0035 17.0 9.5 0.64 9.7 1.3 3.2 3 0 0 3 3 3 2 Putative cell-wall binding lipoprotein BLOC1_2 PF10046.9 ETS87097.1 - 0.0038 17.5 6.9 1.5 9.1 0.1 3.7 3 0 0 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 FH2 PF02181.23 ETS87097.1 - 0.005 16.0 2.1 0.1 11.7 0.0 2.8 3 0 0 3 3 3 1 Formin Homology 2 Domain PHM7_cyt PF14703.6 ETS87097.1 - 0.0068 16.7 0.9 0.73 10.1 0.2 2.4 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Sipho_Gp157 PF05565.11 ETS87097.1 - 0.0081 16.2 8.4 0.11 12.5 0.1 3.2 3 0 0 3 3 3 1 Siphovirus Gp157 ATF7IP_BD PF16788.5 ETS87097.1 - 0.0087 16.2 0.6 0.075 13.1 0.0 2.4 3 0 0 3 3 2 1 ATF-interacting protein binding domain Phage_holin_6_1 PF09682.10 ETS87097.1 - 0.011 16.2 0.5 4 7.9 0.5 2.4 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) MRPL52 PF18699.1 ETS87097.1 - 0.017 15.3 6.1 0.23 11.7 0.1 3.4 3 0 0 3 3 3 0 Mitoribosomal protein mL52 DUF3450 PF11932.8 ETS87097.1 - 0.018 14.3 9.5 0.056 12.7 0.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) PspA_IM30 PF04012.12 ETS87097.1 - 0.022 14.3 12.5 0.75 9.3 3.2 3.3 3 0 0 3 3 3 0 PspA/IM30 family DUF1192 PF06698.11 ETS87097.1 - 0.026 14.6 16.5 0.25 11.4 2.9 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) TMF_TATA_bd PF12325.8 ETS87097.1 - 0.027 14.7 7.8 6.5 7.0 0.1 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.10 ETS87097.1 - 0.03 14.5 5.1 0.37 11.0 0.1 3.3 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.11 ETS87097.1 - 0.04 13.7 11.3 0.13 12.1 0.9 3.5 3 0 0 3 3 3 0 Phage minor structural protein GP20 DUF4201 PF13870.6 ETS87097.1 - 0.12 12.1 8.5 0.51 10.1 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) STAT_alpha PF01017.20 ETS87097.1 - 0.14 12.0 2.6 0.28 11.0 1.2 2.1 2 1 0 2 2 2 0 STAT protein, all-alpha domain DUF1664 PF07889.12 ETS87097.1 - 0.17 11.9 7.1 2.5 8.1 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 ETS87097.1 - 0.22 11.6 16.9 1.6 8.8 0.3 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein BRE1 PF08647.11 ETS87097.1 - 0.25 11.4 9.6 0.36 10.9 0.1 3.3 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Halogen_Hydrol PF10112.9 ETS87097.1 - 0.4 10.7 2.4 7.1 6.6 0.0 2.8 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF4407 PF14362.6 ETS87097.1 - 0.42 9.9 15.9 0.46 9.8 5.4 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) ATP-synt_E PF05680.12 ETS87097.1 - 0.5 10.7 0.0 0.5 10.7 0.0 2.7 3 0 0 3 3 2 0 ATP synthase E chain Uds1 PF15456.6 ETS87097.1 - 0.58 10.3 9.5 1.7 8.8 3.0 2.8 2 1 0 2 2 2 0 Up-regulated During Septation TMPIT PF07851.13 ETS87097.1 - 0.59 9.3 4.6 13 4.9 0.3 2.8 3 0 0 3 3 3 0 TMPIT-like protein Spectrin PF00435.21 ETS87097.1 - 0.6 10.6 10.3 3.2 8.3 0.6 3.9 4 1 0 4 4 3 0 Spectrin repeat ZapB PF06005.12 ETS87097.1 - 0.8 10.2 12.8 1.3 9.5 0.1 3.4 3 1 0 3 3 3 0 Cell division protein ZapB Spore_III_AB PF09548.10 ETS87097.1 - 0.81 9.8 7.4 0.33 11.0 0.7 2.8 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DivIC PF04977.15 ETS87097.1 - 0.81 9.5 14.9 1.4 8.7 1.4 3.5 3 0 0 3 3 3 0 Septum formation initiator XhlA PF10779.9 ETS87097.1 - 1.2 9.4 16.2 0.087 13.0 1.5 3.8 3 0 0 3 3 3 0 Haemolysin XhlA AAA_lid_9 PF17871.1 ETS87097.1 - 1.2 9.1 8.8 3.7 7.5 0.4 3.1 3 0 0 3 3 3 0 AAA lid domain GrpE PF01025.19 ETS87097.1 - 1.3 8.7 9.0 0.89 9.2 0.4 3.1 2 1 0 2 2 2 0 GrpE KfrA_N PF11740.8 ETS87097.1 - 1.5 9.5 10.2 0.48 11.1 2.3 3.1 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term APG6_N PF17675.1 ETS87097.1 - 1.8 9.1 20.4 11 6.5 1.0 3.3 2 1 1 3 3 3 0 Apg6 coiled-coil region Spc24 PF08286.11 ETS87097.1 - 2 8.7 10.9 3.1 8.1 0.5 3.3 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 CENP-H PF05837.12 ETS87097.1 - 2 8.9 8.4 12 6.4 2.1 3.3 3 0 0 3 3 3 0 Centromere protein H (CENP-H) LPP PF04728.13 ETS87097.1 - 2.4 8.6 8.7 3.8 8.0 0.4 3.6 4 0 0 4 4 3 0 Lipoprotein leucine-zipper DUF948 PF06103.11 ETS87097.1 - 2.6 8.3 4.4 13 6.1 0.8 3.2 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) SKA2 PF16740.5 ETS87097.1 - 2.8 7.8 6.1 13 5.6 0.9 3.1 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 COG2 PF06148.11 ETS87097.1 - 3 7.9 7.8 37 4.4 0.8 3.8 3 1 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Fzo_mitofusin PF04799.13 ETS87097.1 - 3.2 7.3 8.6 3.4 7.2 0.7 3.1 3 0 0 3 3 3 0 fzo-like conserved region Prefoldin_2 PF01920.20 ETS87097.1 - 3.3 7.7 12.9 11 6.1 1.7 3.6 3 0 0 3 3 3 0 Prefoldin subunit Jnk-SapK_ap_N PF09744.9 ETS87097.1 - 3.4 7.9 12.1 2.9 8.1 2.4 3.2 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 CHD5 PF04420.14 ETS87097.1 - 3.8 7.4 5.1 11 5.8 0.3 2.6 2 0 0 2 2 2 0 CHD5-like protein DUF4337 PF14235.6 ETS87097.1 - 3.8 7.6 9.2 12 5.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) V_ATPase_I PF01496.19 ETS87097.1 - 3.9 5.3 3.9 12 3.7 0.8 2.1 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family YabA PF06156.13 ETS87097.1 - 4.4 8.0 4.7 24 5.6 0.3 3.1 3 0 0 3 3 3 0 Initiation control protein YabA AAA_13 PF13166.6 ETS87097.1 - 5.3 5.6 9.6 43 2.5 9.9 2.1 1 1 0 1 1 1 0 AAA domain DASH_Duo1 PF08651.10 ETS87097.1 - 5.7 6.8 7.9 8.3 6.3 0.0 3.8 4 1 1 5 5 3 0 DASH complex subunit Duo1 THOC7 PF05615.13 ETS87097.1 - 5.9 7.2 14.9 0.91 9.8 2.0 3.3 3 0 0 3 3 3 0 Tho complex subunit 7 Phage_Mu_Gam PF07352.12 ETS87097.1 - 7.5 6.4 11.1 0.68 9.8 0.7 3.1 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein Med21 PF11221.8 ETS87097.1 - 7.9 6.7 18.5 21 5.3 0.9 3.8 2 1 1 3 3 3 0 Subunit 21 of Mediator complex Podoplanin PF05808.11 ETS87098.1 - 0.013 15.6 0.7 0.02 15.0 0.7 1.2 1 0 0 1 1 1 0 Podoplanin VSP PF03302.13 ETS87098.1 - 0.04 12.8 0.1 0.04 12.8 0.1 2.0 2 0 0 2 2 2 0 Giardia variant-specific surface protein CDH PF02611.15 ETS87098.1 - 0.18 11.4 0.0 0.25 10.9 0.0 1.1 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase Granulin PF00396.18 ETS87098.1 - 4 7.8 10.3 7.8 6.9 5.9 2.3 1 1 1 2 2 2 0 Granulin Ribosomal_S28e PF01200.18 ETS87099.1 - 1.2e-31 108.5 1.9 1.3e-31 108.4 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e ThiS PF02597.20 ETS87100.1 - 1.9e-07 31.6 0.0 2.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 ThiS family NACHT PF05729.12 ETS87101.1 - 1.3e-10 41.4 0.1 2.4e-05 24.3 0.1 2.8 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 ETS87101.1 - 2.1e-05 25.0 0.1 0.00012 22.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain SesA PF17107.5 ETS87101.1 - 5.7e-05 23.3 0.9 0.0002 21.6 0.9 1.9 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 ETS87101.1 - 0.00013 22.2 0.0 0.00068 19.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 ETS87101.1 - 0.0019 18.8 0.0 0.0067 16.9 0.0 1.9 1 0 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 ETS87101.1 - 0.0026 18.1 0.0 0.0095 16.3 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 ETS87101.1 - 0.0029 18.1 0.0 0.043 14.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 ETS87101.1 - 0.0083 15.9 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ETS87101.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 ETS87101.1 - 0.049 13.5 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 ETS87101.1 - 0.19 12.2 2.8 0.5 10.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain Aldolase_II PF00596.21 ETS87102.1 - 3.6e-49 167.2 0.1 4.5e-49 166.9 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF2138 PF09909.9 ETS87102.1 - 0.16 10.3 0.0 0.22 9.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) Fungal_trans PF04082.18 ETS87103.1 - 2.9e-20 72.4 0.1 7.9e-20 71.0 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS87103.1 - 1.8e-09 37.6 8.9 4.3e-09 36.4 8.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ProSAAS PF07259.12 ETS87103.1 - 0.011 15.7 0.1 0.023 14.7 0.1 1.4 1 0 0 1 1 1 0 ProSAAS precursor Peptidase_M20 PF01546.28 ETS87104.1 - 5.2e-28 98.2 0.1 6.6e-28 97.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ETS87104.1 - 6.6e-07 29.2 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain PriA_C PF18074.1 ETS87104.1 - 0.19 12.6 0.0 0.46 11.3 0.0 1.7 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain FAD_binding_3 PF01494.19 ETS87105.1 - 3.2e-12 46.4 0.0 2.2e-11 43.6 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS87105.1 - 0.0082 15.4 0.0 0.027 13.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ETS87105.1 - 0.028 13.7 0.0 0.072 12.4 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NmrA PF05368.13 ETS87106.1 - 3e-27 95.7 0.0 3.7e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS87106.1 - 2e-05 24.6 0.0 4e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 ETS87106.1 - 0.00072 20.0 0.0 0.0021 18.5 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 ETS87106.1 - 0.0091 15.5 0.0 0.05 13.1 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ETS87106.1 - 0.012 14.7 0.2 0.017 14.1 0.2 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glu_dehyd_C PF16912.5 ETS87106.1 - 0.062 12.8 0.1 0.8 9.1 0.0 2.1 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus LigB PF02900.18 ETS87107.1 - 1.3e-33 116.2 0.0 1.8e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Fungal_trans PF04082.18 ETS87108.1 - 2.6e-08 33.2 0.3 4.1e-08 32.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS87108.1 - 3.9e-08 33.3 9.1 8.1e-08 32.3 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5624 PF18538.1 ETS87108.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) 2-Hacid_dh_C PF02826.19 ETS87109.1 - 6.7e-37 126.6 0.0 1.1e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS87109.1 - 1.4e-23 83.0 0.1 1.7e-23 82.8 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 ETS87109.1 - 0.00029 21.3 0.2 0.4 11.2 0.1 2.3 2 0 0 2 2 2 2 XdhC Rossmann domain Clr5 PF14420.6 ETS87110.1 - 4.8e-09 36.3 0.3 1.5e-08 34.7 0.3 1.8 1 0 0 1 1 1 1 Clr5 domain Uso1_p115_head PF04869.14 ETS87110.1 - 0.0065 15.7 0.1 0.0099 15.0 0.1 1.2 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region FMN_red PF03358.15 ETS87111.1 - 1.8e-10 40.8 0.0 2.2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 ETS87111.1 - 1.9e-06 28.1 0.2 1.5e-05 25.2 0.2 2.4 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 ETS87111.1 - 2.9e-06 27.1 0.0 3.6e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 ETS87111.1 - 0.00085 19.6 0.0 0.023 15.0 0.0 2.1 1 1 1 2 2 2 1 Flavodoxin domain MORN PF02493.20 ETS87111.1 - 0.0073 16.1 3.9 0.95 9.5 0.6 2.5 2 0 0 2 2 2 2 MORN repeat DUF2462 PF09495.10 ETS87112.1 - 0.017 15.8 0.1 0.028 15.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2462) AT_hook PF02178.19 ETS87112.1 - 0.13 12.2 7.7 0.42 10.6 7.7 1.9 1 0 0 1 1 1 0 AT hook motif GFA PF04828.14 ETS87114.1 - 1.1e-06 28.8 0.0 2.1e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 ETS87114.1 - 0.0028 17.3 0.1 0.0028 17.3 0.1 2.5 3 0 0 3 3 3 1 NADH pyrophosphatase zinc ribbon domain Ribosomal_L37e PF01907.19 ETS87114.1 - 0.16 12.1 6.9 4.1 7.6 0.1 3.2 2 1 1 3 3 3 0 Ribosomal protein L37e zf-CSL PF05207.13 ETS87114.1 - 0.34 10.7 3.6 1.5 8.6 1.2 2.4 2 0 0 2 2 2 0 CSL zinc finger p450 PF00067.22 ETS87115.1 - 3.7e-26 91.9 0.0 8.3e-26 90.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 SpvB PF03534.13 ETS87117.1 - 1.9e-97 326.0 0.0 3.8e-97 325.0 0.0 1.6 1 0 0 1 1 1 1 Salmonella virulence plasmid 65kDa B protein TcdB_toxin_midN PF12256.8 ETS87117.1 - 3.7e-32 111.1 3.1 5.5e-29 100.8 0.1 5.2 5 0 0 5 5 5 1 Insecticide toxin TcdB middle/N-terminal region TcdB_toxin_midC PF12255.8 ETS87117.1 - 3.4e-25 88.8 0.3 9e-25 87.5 0.3 1.7 1 0 0 1 1 1 1 Insecticide toxin TcdB middle/C-terminal region VCBS PF13517.6 ETS87117.1 - 0.00028 21.4 19.0 0.0019 18.7 0.2 5.5 3 2 2 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 ETS87117.1 - 0.17 12.0 5.0 8.9 6.5 0.4 4.0 3 0 0 3 3 3 0 FG-GAP repeat RHS_repeat PF05593.14 ETS87117.1 - 4.1 8.0 31.1 0.16 12.5 0.4 9.0 8 2 0 8 8 8 0 RHS Repeat Leg1 PF05612.12 ETS87118.1 - 0.0072 15.5 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 Leg1 TcA_TcB_BD PF18276.1 ETS87119.1 - 1.4e-110 368.9 0.1 2.3e-110 368.2 0.1 1.3 1 0 0 1 1 1 1 Tc toxin complex TcA C-terminal TcB-binding domain Neuraminidase PF18413.1 ETS87119.1 - 9.6e-40 136.0 0.2 4.1e-39 133.9 0.1 2.1 2 0 0 2 2 2 1 Neuraminidase-like domain VRP1 PF03538.14 ETS87119.1 - 0.022 14.2 0.5 0.07 12.5 0.0 2.0 2 0 0 2 2 2 0 Salmonella virulence plasmid 28.1kDa A protein adh_short PF00106.25 ETS87120.1 - 8e-21 74.4 0.0 1e-18 67.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS87120.1 - 6.4e-14 52.1 0.0 6e-13 48.9 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS87120.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 KR domain 2-Hacid_dh_C PF02826.19 ETS87120.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_hydro_115 PF15979.5 ETS87121.1 - 7.3e-131 436.6 0.1 9.7e-131 436.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 ETS87121.1 - 6.9e-56 188.8 0.0 1.6e-55 187.6 0.0 1.7 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Lipase_GDSL PF00657.22 ETS87122.1 - 2.9e-06 27.4 0.5 4.2e-06 26.9 0.5 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HET PF06985.11 ETS87123.1 - 4.7e-17 62.7 0.2 1.1e-16 61.5 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Helo_like_N PF17111.5 ETS87124.1 - 3.5e-08 33.1 2.3 3.5e-08 33.1 2.3 2.5 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Ank_2 PF12796.7 ETS87124.1 - 0.0031 18.1 0.0 0.011 16.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS87124.1 - 0.0047 17.5 0.5 0.95 10.1 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) NYD-SP12_N PF15015.6 ETS87124.1 - 0.046 12.1 0.3 0.07 11.5 0.3 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Ank PF00023.30 ETS87124.1 - 0.11 13.0 0.0 0.53 10.8 0.0 2.3 1 0 0 1 1 1 0 Ankyrin repeat p450 PF00067.22 ETS87125.1 - 4.2e-47 160.9 0.0 6.2e-47 160.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF3632 PF12311.8 ETS87126.1 - 8e-17 62.2 1.0 1.5e-16 61.3 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Amidase PF01425.21 ETS87127.1 - 1.1e-30 107.0 0.3 2.4e-30 105.9 0.2 1.5 2 0 0 2 2 2 1 Amidase PD-C2-AF1 PF09310.10 ETS87128.1 - 0.04 13.3 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 Big_4 PF07532.11 ETS87128.1 - 0.058 13.1 1.7 0.11 12.2 1.7 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) Arginase PF00491.21 ETS87129.1 - 1.9e-90 303.2 0.0 2.2e-90 303.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family Sugar_tr PF00083.24 ETS87130.1 - 4.3e-102 342.3 29.1 5e-102 342.1 29.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS87130.1 - 7.4e-33 113.9 31.3 7.4e-33 113.9 31.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Ank_2 PF12796.7 ETS87131.1 - 2.6e-62 207.4 0.0 3.2e-16 59.7 0.0 5.7 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ETS87131.1 - 1.1e-48 162.7 8.3 2.7e-08 33.9 0.0 10.2 2 2 8 10 10 10 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS87131.1 - 1.2e-48 162.9 0.3 4.3e-09 36.7 0.0 9.5 3 2 7 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 ETS87131.1 - 4.1e-45 150.3 11.1 0.0013 19.1 0.0 11.8 11 0 0 11 11 11 10 Ankyrin repeat Ank_3 PF13606.6 ETS87131.1 - 1.8e-38 126.2 0.2 0.0011 19.2 0.0 11.6 11 0 0 11 11 11 8 Ankyrin repeat NACHT PF05729.12 ETS87131.1 - 1.5e-07 31.5 0.1 7e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 ETS87131.1 - 0.00052 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ETS87131.1 - 0.00061 20.2 0.0 0.0016 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF4988 PF16378.5 ETS87131.1 - 0.00063 19.5 0.2 0.039 13.6 0.0 3.0 1 1 2 3 3 3 1 Domain of unknown function ATPase_2 PF01637.18 ETS87131.1 - 0.0029 17.5 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 ETS87131.1 - 0.0069 16.8 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 ETS87131.1 - 0.015 14.5 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 ETS87131.1 - 0.074 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 ETS87131.1 - 0.099 13.2 0.0 0.24 11.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 ETS87131.1 - 0.13 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain HET PF06985.11 ETS87132.1 - 1.5e-09 38.3 12.5 2.8e-08 34.2 4.3 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.11 ETS87133.1 - 4.7e-14 53.0 4.3 7e-11 42.7 0.2 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 ETS87133.1 - 1.1e-06 29.1 0.0 2.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS87133.1 - 5.4e-05 23.3 0.0 0.014 15.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 ETS87133.1 - 0.00045 20.7 0.0 0.027 15.0 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ETS87133.1 - 0.045 14.2 0.0 0.19 12.3 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 ETS87133.1 - 0.06 13.7 0.0 0.17 12.2 0.0 1.8 1 1 1 2 2 2 0 Ankyrin repeats (many copies) APH PF01636.23 ETS87134.1 - 1.4e-13 51.3 0.0 1.9e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 ETS87134.1 - 3.6e-06 26.7 0.0 6.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 ETS87134.1 - 0.04 13.1 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Fructosamine kinase DUF1679 PF07914.11 ETS87134.1 - 0.041 12.7 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 ETS87134.1 - 0.082 12.3 0.0 8 5.7 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain EcKinase PF02958.20 ETS87134.1 - 0.22 10.8 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DAO PF01266.24 ETS87135.1 - 1.9e-28 100.0 0.0 2.5e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS87135.1 - 6.6e-07 29.5 0.0 2.1e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS87135.1 - 0.00022 20.5 0.0 0.00078 18.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 ETS87135.1 - 0.0065 16.5 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.27 ETS87135.1 - 0.0068 16.9 0.1 0.016 15.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ETS87135.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 ETS87135.1 - 0.02 14.1 0.1 0.042 13.1 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 ETS87135.1 - 0.054 13.4 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 ETS87135.1 - 0.079 13.2 0.0 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Glyco_transf_4 PF13439.6 ETS87135.1 - 0.091 12.8 0.0 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase Family 4 NAD_binding_2 PF03446.15 ETS87135.1 - 0.11 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.14 ETS87135.1 - 0.13 10.9 0.1 0.6 8.7 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Amidase PF01425.21 ETS87136.1 - 3.6e-32 111.9 0.3 5.7e-32 111.3 0.3 1.2 1 0 0 1 1 1 1 Amidase NT5C PF06941.12 ETS87136.1 - 0.042 13.7 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Abhydrolase_8 PF06259.12 ETS87136.1 - 0.071 12.7 0.1 0.21 11.2 0.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase Amino_oxidase PF01593.24 ETS87137.1 - 7.2e-39 134.3 0.1 8.8e-39 134.0 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ETS87137.1 - 1.6e-07 31.5 0.0 5.5e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS87137.1 - 0.00084 19.0 0.8 0.0017 18.0 0.4 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ETS87137.1 - 0.0047 16.2 0.0 0.0086 15.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ETS87137.1 - 0.037 13.3 0.1 0.066 12.4 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 ETS87137.1 - 0.054 13.1 0.3 4.2 6.9 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 ETS87137.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.6 ETS87137.1 - 0.17 11.1 0.1 0.43 9.8 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 ETS87138.1 - 6.4e-44 150.3 49.0 3e-41 141.5 48.0 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS87138.1 - 5.7e-14 51.8 10.0 5.7e-14 51.8 10.0 3.5 3 1 1 4 4 4 2 Sugar (and other) transporter PetL PF05115.14 ETS87138.1 - 2 8.4 9.8 8 6.5 2.3 4.1 3 0 0 3 3 3 0 Cytochrome B6-F complex subunit VI (PetL) PALP PF00291.25 ETS87139.1 - 2e-36 125.9 0.0 3.9e-36 125.0 0.0 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.20 ETS87139.1 - 2.5e-05 24.7 0.0 0.00015 22.3 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain 2-Hacid_dh_C PF02826.19 ETS87140.1 - 3.5e-45 153.5 0.1 6.5e-45 152.7 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS87140.1 - 6.5e-21 74.4 0.0 8.5e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.6 ETS87140.1 - 0.0017 18.8 0.1 0.005 17.3 0.0 1.8 2 0 0 2 2 2 1 XdhC Rossmann domain IlvN PF07991.12 ETS87140.1 - 0.0037 16.9 0.1 0.036 13.7 0.1 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 ETS87140.1 - 0.0039 17.3 0.1 0.016 15.2 0.0 2.0 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 ETS87140.1 - 0.019 14.2 0.9 0.073 12.4 0.1 2.2 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 ETS87141.1 - 2.8e-18 66.0 20.2 2.8e-18 66.0 20.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_M50 PF02163.22 ETS87141.1 - 0.068 12.4 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M50 Ank_2 PF12796.7 ETS87142.1 - 4.5e-38 129.7 5.0 1.1e-12 48.3 0.2 5.0 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) HET PF06985.11 ETS87142.1 - 2.9e-35 121.8 1.5 2.9e-35 121.8 1.5 2.9 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) Ank_3 PF13606.6 ETS87142.1 - 4.3e-28 94.2 0.6 0.00047 20.4 0.1 8.5 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 ETS87142.1 - 2e-24 85.6 0.9 2.4e-07 31.1 0.1 7.3 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS87142.1 - 1.2e-23 82.8 5.8 0.0002 21.6 0.0 7.0 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 ETS87142.1 - 1.4e-16 60.1 9.1 0.00025 21.3 0.2 7.5 7 0 0 7 7 7 4 Ankyrin repeat Nop14 PF04147.12 ETS87142.1 - 1.1 7.4 7.7 1.6 6.9 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 ETS87142.1 - 6.6 6.0 13.9 13 5.0 13.9 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 ETS87142.1 - 6.8 4.8 10.5 11 4.2 10.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_43 PF04616.14 ETS87143.1 - 4.9e-67 226.2 3.7 7.1e-67 225.7 3.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ETS87143.1 - 1.1e-11 44.8 0.0 1.8e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Abhydrolase_6 PF12697.7 ETS87144.1 - 9.1e-11 42.8 0.0 1e-10 42.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS87144.1 - 0.011 15.1 0.0 0.074 12.3 0.0 2.2 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Acyl-CoA_dh_N PF02771.16 ETS87144.1 - 0.086 13.5 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain LIDHydrolase PF10230.9 ETS87144.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.4 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase Mob1_phocein PF03637.17 ETS87145.1 - 9.2e-43 146.2 0.3 1.4e-42 145.6 0.3 1.3 1 0 0 1 1 1 1 Mob1/phocein family Leo1 PF04004.13 ETS87146.1 - 2.3e-33 115.4 0.1 5.1e-33 114.3 0.1 1.6 1 0 0 1 1 1 1 Leo1-like protein Anp1 PF03452.14 ETS87146.1 - 0.1 12.0 1.8 0.17 11.2 1.8 1.3 1 0 0 1 1 1 0 Anp1 DUF3716 PF12511.8 ETS87147.1 - 1.7e-08 34.4 8.6 2.8e-08 33.7 8.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF3336 PF11815.8 ETS87148.1 - 1.2e-34 119.0 0.3 1.3e-33 115.6 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 ETS87148.1 - 8.3e-12 45.7 2.1 1.3e-11 45.0 0.8 2.0 2 1 0 2 2 2 1 Patatin-like phospholipase Sm_multidrug_ex PF06695.11 ETS87148.1 - 0.18 12.5 0.7 1 10.0 0.3 2.2 2 0 0 2 2 2 0 Putative small multi-drug export protein FOXP-CC PF16159.5 ETS87150.1 - 0.14 12.8 10.6 0.33 11.6 1.6 3.0 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 ETS87152.1 - 3.5e-13 49.2 11.4 3.6e-06 27.1 2.4 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ETS87152.1 - 2.6e-11 43.4 13.5 1.9e-07 31.2 0.2 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ETS87152.1 - 6.4e-09 35.9 10.4 0.0004 21.0 1.5 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ETS87152.1 - 3e-08 33.4 5.4 0.00032 20.6 0.3 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 ETS87152.1 - 5.1e-05 23.5 2.5 0.013 15.8 0.2 3.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ETS87152.1 - 0.0018 18.5 11.8 0.088 13.1 0.1 4.5 5 0 0 5 5 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 ETS87152.1 - 0.017 14.9 6.9 0.41 10.5 0.7 3.7 4 0 0 4 4 4 0 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 ETS87152.1 - 0.1 13.1 0.8 0.24 11.9 0.8 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2HE PF16278.5 ETS87152.1 - 0.3 11.6 2.2 9 6.8 0.3 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 ETS87152.1 - 0.32 11.3 3.2 17 5.8 0.1 2.4 1 1 1 2 2 2 0 LIM domain zf-Di19 PF05605.12 ETS87152.1 - 4 7.8 7.3 0.18 12.1 1.4 1.8 2 0 0 2 2 1 0 Drought induced 19 protein (Di19), zinc-binding C5HCH PF17982.1 ETS87152.1 - 4.1 7.6 6.2 31 4.8 1.3 2.7 1 1 1 2 2 2 0 NSD Cys-His rich domain AOX PF01786.17 ETS87153.1 - 2.6e-89 298.5 0.4 3.1e-89 298.2 0.4 1.1 1 0 0 1 1 1 1 Alternative oxidase eIF3_subunit PF08597.10 ETS87154.1 - 3.6e-74 249.7 31.6 4.4e-74 249.4 31.6 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PRP4 PF08799.11 ETS87154.1 - 0.079 12.5 1.3 0.93 9.1 3.4 1.7 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like Vpu PF00558.19 ETS87154.1 - 0.76 9.6 5.2 1.9 8.3 5.2 1.7 1 0 0 1 1 1 0 Vpu protein Nop53 PF07767.11 ETS87154.1 - 1.7 7.9 25.8 1.5 8.2 17.3 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) PAN_4 PF14295.6 ETS87155.1 - 0.0023 17.8 6.0 0.022 14.7 0.8 3.1 3 0 0 3 3 3 2 PAN domain MDM31_MDM32 PF08118.11 ETS87156.1 - 4.6e-243 807.6 0.0 2e-241 802.2 0.0 2.0 2 0 0 2 2 2 1 Yeast mitochondrial distribution and morphology (MDM) proteins CCDC53 PF10152.9 ETS87156.1 - 0.075 13.4 4.2 0.1 13.0 0.3 2.6 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex DUF4518 PF15008.6 ETS87156.1 - 0.2 10.8 0.2 0.38 9.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Ribosomal_60s PF00428.19 ETS87156.1 - 0.27 11.8 0.1 0.27 11.8 0.1 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein CAC1F_C PF16885.5 ETS87156.1 - 0.71 9.5 4.9 0.31 10.7 1.9 1.7 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term KH_8 PF17903.1 ETS87157.1 - 2.4e-06 27.5 0.0 4.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 ETS87157.1 - 0.0011 18.7 1.6 0.0027 17.5 1.6 1.7 1 0 0 1 1 1 1 KH domain Rad60-SLD PF11976.8 ETS87158.1 - 8.9e-15 54.3 0.8 4e-14 52.2 0.4 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ETS87158.1 - 7.6e-05 22.4 0.2 0.00027 20.6 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_5 PF18037.1 ETS87158.1 - 0.015 15.6 0.1 0.047 14.1 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain Atg8 PF02991.16 ETS87158.1 - 0.13 12.4 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Peptidase_S64 PF08192.11 ETS87158.1 - 2.9 6.3 8.2 3.3 6.1 8.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF4337 PF14235.6 ETS87158.1 - 5.6 7.1 8.4 10 6.2 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Macoilin PF09726.9 ETS87158.1 - 9.8 4.6 15.5 13 4.2 15.5 1.1 1 0 0 1 1 1 0 Macoilin family LSM PF01423.22 ETS87159.1 - 1.4e-20 72.7 0.1 1.7e-20 72.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ETS87159.1 - 0.00062 19.9 0.1 0.00073 19.6 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 ETS87159.1 - 0.037 14.1 0.1 0.043 13.9 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain Hfq PF17209.3 ETS87159.1 - 0.054 13.1 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Methyltransf_11 PF08241.12 ETS87160.1 - 9.9e-13 48.6 0.0 1.7e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS87160.1 - 2.6e-11 44.1 0.0 5.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS87160.1 - 3e-05 23.9 0.0 7.9e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS87160.1 - 6.5e-05 22.4 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ETS87160.1 - 0.00026 21.7 0.0 0.00046 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS87160.1 - 0.0016 18.3 0.0 0.0048 16.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 ETS87160.1 - 0.056 12.5 0.0 0.076 12.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CAP59_mtransfer PF11735.8 ETS87161.1 - 2.3e-77 260.0 0.0 2.8e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Tim17 PF02466.19 ETS87162.1 - 2.7e-14 53.5 1.4 5.9e-14 52.4 1.5 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 ETS87162.1 - 0.0081 16.3 3.8 0.65 10.2 1.5 2.2 1 1 1 2 2 2 2 Family of unknown function (DUF5518) DUF2627 PF11118.8 ETS87163.1 - 0.042 14.4 0.6 1.3 9.7 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) Abhydrolase_3 PF07859.13 ETS87164.1 - 7.3e-29 101.1 0.0 1e-28 100.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS87164.1 - 6.1e-06 25.4 0.0 9.2e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Fungal_trans_2 PF11951.8 ETS87165.1 - 4.9e-07 28.9 0.1 6.5e-07 28.5 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMN_bind_2 PF04299.12 ETS87165.1 - 0.2 11.4 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative FMN-binding domain DUF3253 PF11625.8 ETS87166.1 - 1.2e-26 92.8 0.1 1.4e-26 92.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) PCB_OB PF17092.5 ETS87166.1 - 0.1 13.3 0.0 0.14 13.0 0.0 1.1 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain zf-RING_2 PF13639.6 ETS87167.1 - 1.6e-08 34.8 8.7 1.6e-08 34.8 8.7 2.0 3 0 0 3 3 1 1 Ring finger domain zf-C3HC4 PF00097.25 ETS87167.1 - 9.9e-08 31.7 7.9 9.9e-08 31.7 7.9 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ETS87167.1 - 3.5e-06 26.8 7.8 3.5e-06 26.8 6.2 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ETS87167.1 - 6e-06 26.1 5.9 6e-06 26.1 5.9 2.5 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ETS87167.1 - 1.4e-05 25.0 4.0 1.4e-05 25.0 4.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 ETS87167.1 - 2.2e-05 24.6 9.1 2.2e-05 24.6 9.1 2.3 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 ETS87167.1 - 9.4e-05 22.5 3.9 9.4e-05 22.5 3.9 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 ETS87167.1 - 0.00012 21.8 10.1 0.00012 21.8 10.1 3.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 ETS87167.1 - 0.0048 17.1 3.5 0.014 15.7 3.5 1.8 1 0 0 1 1 1 1 zinc-ribbon ThiS-like PF14453.6 ETS87167.1 - 0.088 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 ThiS-like ubiquitin SMN PF06003.12 ETS87167.1 - 0.09 12.0 0.5 0.17 11.1 0.5 1.5 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) YABBY PF04690.13 ETS87167.1 - 0.12 13.0 1.9 0.16 12.5 1.9 1.3 1 0 0 1 1 1 0 YABBY protein zf-Nse PF11789.8 ETS87167.1 - 0.23 11.3 9.5 0.074 12.9 4.7 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 ETS87167.1 - 0.55 10.3 13.3 0.035 14.2 7.7 1.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.6 ETS87167.1 - 1.2 9.3 8.6 0.16 12.1 4.4 1.7 2 0 0 2 2 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 ETS87167.1 - 3.7 7.4 15.8 0.046 13.5 5.8 2.8 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-MYND PF01753.18 ETS87169.1 - 1.1e-09 38.2 16.1 1.8e-09 37.5 16.1 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ETS87169.1 - 0.43 10.9 10.3 0.94 9.8 10.3 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Siva PF05458.12 ETS87169.1 - 2.5 7.8 10.6 3.9 7.1 10.6 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) HET PF06985.11 ETS87170.1 - 3.9e-16 59.7 0.7 3.9e-16 59.7 0.7 2.7 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) EGF_2 PF07974.13 ETS87171.1 - 0.0002 21.6 7.0 0.00043 20.6 7.0 1.6 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 ETS87171.1 - 0.017 15.7 2.1 0.04 14.6 2.1 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EB PF01683.18 ETS87171.1 - 0.019 15.2 0.4 0.035 14.4 0.4 1.3 1 0 0 1 1 1 0 EB module T2SSG PF08334.11 ETS87171.1 - 0.12 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G EGF PF00008.27 ETS87171.1 - 0.28 11.5 3.7 0.55 10.6 3.7 1.5 1 0 0 1 1 1 0 EGF-like domain Sugar_tr PF00083.24 ETS87172.1 - 3.9e-100 335.9 28.0 4.4e-100 335.7 28.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS87172.1 - 2.5e-28 99.0 31.3 9.4e-21 74.1 5.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2615 PF11027.8 ETS87172.1 - 1.3 9.2 3.4 7.8 6.7 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) FAD_binding_4 PF01565.23 ETS87173.1 - 1e-21 77.1 1.7 1.6e-21 76.5 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain Hydrolase_4 PF12146.8 ETS87174.1 - 0.0007 18.9 0.0 0.0042 16.4 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS87174.1 - 0.0014 18.3 0.1 0.0049 16.6 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF805 PF05656.14 ETS87175.1 - 1.5 9.3 11.9 5.3 7.5 11.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF1461 PF07314.11 ETS87175.1 - 4 7.3 8.0 1.2 9.0 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) WBS_methylT PF12589.8 ETS87177.1 - 1e-14 55.0 4.4 1.9e-14 54.2 4.4 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 ETS87177.1 - 3e-11 43.8 0.0 5.3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS87177.1 - 2.1e-09 37.9 0.0 4.8e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS87177.1 - 0.00018 22.2 0.0 0.00099 19.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS87177.1 - 0.0014 18.5 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ETS87177.1 - 0.003 17.4 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 ETS87177.1 - 0.11 12.5 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain ZirS_C PF16583.5 ETS87177.1 - 0.14 11.7 0.2 0.23 11.0 0.2 1.3 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain Erv26 PF04148.13 ETS87178.1 - 2.9e-89 298.4 5.0 3.4e-89 298.1 5.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF996 PF06195.13 ETS87178.1 - 0.0023 18.2 4.7 0.0035 17.6 2.8 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF996) DUF1970 PF09301.10 ETS87178.1 - 0.068 13.4 0.0 0.22 11.8 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1970) ABC_tran PF00005.27 ETS87179.1 - 7.7e-55 185.2 0.1 1.8e-29 103.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 ETS87179.1 - 3.2e-23 82.4 38.5 2e-18 66.6 14.9 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 ETS87179.1 - 1.2e-17 64.6 0.2 6e-05 23.0 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ETS87179.1 - 4.9e-09 36.0 0.1 0.3 10.5 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 ETS87179.1 - 2.9e-06 27.3 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_23 PF13476.6 ETS87179.1 - 4.8e-06 27.2 1.5 0.026 15.0 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 ETS87179.1 - 6.5e-06 26.5 0.1 0.33 11.2 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 ETS87179.1 - 1e-05 25.2 1.8 0.015 15.0 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 ETS87179.1 - 8.7e-05 22.3 0.6 0.079 12.7 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 ETS87179.1 - 0.00016 22.1 0.3 0.42 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain SRP54 PF00448.22 ETS87179.1 - 0.00027 20.6 0.1 0.71 9.5 0.0 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_15 PF13175.6 ETS87179.1 - 0.0011 18.8 0.0 0.26 10.9 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 ETS87179.1 - 0.0011 18.9 0.5 0.15 11.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 ETS87179.1 - 0.006 15.9 0.2 3 7.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA PF00004.29 ETS87179.1 - 0.0061 17.0 0.2 4.9 7.6 0.1 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ETS87179.1 - 0.021 14.5 0.3 5.7 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF4162 PF13732.6 ETS87179.1 - 0.026 15.2 0.0 0.43 11.3 0.0 3.0 4 0 0 4 4 2 0 Domain of unknown function (DUF4162) AAA_PrkA PF08298.11 ETS87179.1 - 0.035 13.0 0.1 1.9 7.3 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain AAA_19 PF13245.6 ETS87179.1 - 0.039 14.3 0.5 3.1 8.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 ETS87179.1 - 0.046 12.8 0.8 1.9 7.5 0.2 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_27 PF13514.6 ETS87179.1 - 0.059 12.9 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 ETS87179.1 - 0.11 12.2 0.0 3.6 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ETS87179.1 - 0.18 11.7 0.3 6.8 6.6 0.1 2.9 3 0 0 3 3 3 0 NACHT domain AAA_14 PF13173.6 ETS87179.1 - 0.18 11.8 0.0 18 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 ETS87179.1 - 0.25 10.5 0.2 1.5 7.9 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit Aldedh PF00171.22 ETS87180.1 - 3.8e-152 507.0 0.0 4.2e-152 506.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ETS87180.1 - 0.01 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 ETS87180.1 - 0.026 14.0 0.1 2.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) GMC_oxred_N PF00732.19 ETS87181.1 - 8.6e-61 205.9 0.0 1.1e-60 205.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS87181.1 - 1e-37 129.9 1.1 9e-37 126.8 0.0 2.5 3 0 0 3 3 3 1 GMC oxidoreductase DAO PF01266.24 ETS87181.1 - 2.1e-05 24.3 0.0 0.0002 21.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ETS87181.1 - 8.4e-05 21.8 0.4 0.00015 21.0 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ETS87181.1 - 0.00016 21.8 0.6 0.0004 20.6 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ETS87181.1 - 0.0016 17.6 1.7 0.43 9.6 1.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 ETS87181.1 - 0.011 15.0 0.2 0.18 11.0 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS87181.1 - 0.036 12.8 0.5 0.15 10.7 0.3 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 ETS87181.1 - 0.1 11.7 3.8 0.22 10.6 2.4 2.1 3 0 0 3 3 3 0 FAD binding domain Pyr_redox PF00070.27 ETS87181.1 - 0.23 12.1 1.5 0.72 10.5 0.3 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Zn_clus PF00172.18 ETS87182.1 - 8.6e-08 32.2 13.7 1.5e-07 31.4 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B PF00753.27 ETS87183.1 - 1.5e-05 25.1 2.4 4.8e-05 23.5 2.1 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ETS87183.1 - 0.013 15.0 0.0 0.032 13.7 0.0 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Fungal_trans PF04082.18 ETS87184.1 - 5.1e-20 71.6 0.1 7.5e-20 71.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS87184.1 - 9e-10 38.5 7.8 1.6e-09 37.7 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 ETS87185.1 - 5.3e-25 88.4 0.1 3.6e-24 85.7 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 ETS87185.1 - 4.6e-05 23.6 2.5 0.00011 22.4 2.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS87185.1 - 6.1e-05 22.4 0.2 0.0015 17.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS87185.1 - 0.001 18.7 4.4 0.0078 15.8 5.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS87185.1 - 0.0014 17.8 0.1 0.0019 17.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 ETS87185.1 - 0.0043 16.4 0.1 2.3 7.4 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 ETS87185.1 - 0.013 14.2 0.1 0.016 13.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.23 ETS87185.1 - 0.022 14.7 0.1 0.044 13.8 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 ETS87185.1 - 0.025 13.8 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 ETS87185.1 - 0.032 14.8 3.0 0.088 13.4 1.4 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS87185.1 - 0.041 13.9 1.6 3.1 7.8 0.8 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 ETS87185.1 - 0.064 13.1 1.7 0.13 12.1 1.7 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amdase PF17645.1 ETS87186.1 - 3.8e-18 65.9 0.1 4.6e-18 65.6 0.1 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase Asp_Glu_race PF01177.22 ETS87186.1 - 0.00047 20.1 0.1 0.00067 19.6 0.1 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase MFS_1 PF07690.16 ETS87187.1 - 1.8e-21 76.5 40.2 1.5e-20 73.5 40.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Gram_pos_anchor PF00746.21 ETS87187.1 - 0.088 12.8 1.1 0.28 11.2 1.1 1.9 1 0 0 1 1 1 0 LPXTG cell wall anchor motif LIM_bind PF01803.16 ETS87188.1 - 0.3 10.6 1.3 0.4 10.2 0.0 1.7 2 0 0 2 2 2 0 LIM-domain binding protein MutS_V PF00488.21 ETS87189.1 - 1.5e-70 237.1 0.0 3.8e-70 235.7 0.0 1.8 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ETS87189.1 - 6.3e-34 117.9 2.3 6.3e-34 117.9 2.3 1.8 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.20 ETS87189.1 - 3.3e-28 98.2 0.0 7e-28 97.1 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 ETS87189.1 - 6.6e-09 36.2 0.1 3.3e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 ETS87189.1 - 0.00028 21.2 0.0 0.0014 18.9 0.1 2.3 2 0 0 2 2 2 1 MutS family domain IV DUF4911 PF16256.5 ETS87189.1 - 0.0053 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4911) PRTP PF01366.18 ETS87189.1 - 0.047 11.7 0.0 0.11 10.5 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DUF3865 PF12981.7 ETS87189.1 - 0.19 11.6 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) Glyco_hydro_11 PF00457.17 ETS87190.1 - 1.8e-80 268.8 19.9 2e-80 268.6 19.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Peptidase_S8 PF00082.22 ETS87191.1 - 9.1e-29 100.7 10.3 1.7e-28 99.8 10.2 1.3 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ETS87191.1 - 5.2e-05 23.8 0.0 9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 CYYR1 PF10873.8 ETS87192.1 - 7.2e-06 26.5 1.5 1.8e-05 25.2 1.5 1.6 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 CD99L2 PF12301.8 ETS87192.1 - 0.12 12.6 0.9 0.29 11.4 0.9 1.6 1 0 0 1 1 1 0 CD99 antigen like protein 2 FSA_C PF10479.9 ETS87192.1 - 1.8 6.6 8.0 2.8 6.0 8.0 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus MGC-24 PF05283.11 ETS87192.1 - 3.6 8.0 12.3 5.3 7.5 0.2 2.4 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Tannase PF07519.11 ETS87193.1 - 1.2e-91 308.0 4.9 1.4e-91 307.7 4.9 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 ETS87193.1 - 0.041 13.4 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Na_trans_cytopl PF11933.8 ETS87194.1 - 0.0063 16.3 3.8 0.0071 16.2 3.0 1.3 1 1 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel RSN1_7TM PF02714.15 ETS87195.1 - 5.5e-75 252.2 23.4 8.2e-75 251.6 23.4 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ETS87195.1 - 2.6e-36 124.7 1.2 2.6e-36 124.7 1.2 3.0 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ETS87195.1 - 3.5e-36 125.1 0.0 5.6e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 ETS87195.1 - 0.00016 20.7 2.5 0.00016 20.7 2.5 2.0 1 1 0 2 2 2 1 Calcium-activated chloride channel O-FucT PF10250.9 ETS87196.1 - 1.2e-23 84.4 0.0 1.8e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Cupin_2 PF07883.11 ETS87198.1 - 0.00013 21.6 0.1 0.00021 20.9 0.1 1.4 1 0 0 1 1 1 1 Cupin domain Lyx_isomer PF07385.12 ETS87198.1 - 0.074 12.3 0.0 0.12 11.6 0.0 1.3 1 1 0 1 1 1 0 D-lyxose isomerase Zn_clus PF00172.18 ETS87199.1 - 4.5e-07 29.9 6.0 7.5e-07 29.2 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WAK_assoc PF14380.6 ETS87199.1 - 0.27 12.0 5.4 1.1 10.1 5.4 2.0 1 1 0 1 1 1 0 Wall-associated receptor kinase C-terminal WD40 PF00400.32 ETS87200.1 - 5.2e-56 185.3 35.9 4.3e-11 43.2 0.5 8.9 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS87200.1 - 2e-21 76.1 6.1 0.00011 22.4 0.0 6.5 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS87200.1 - 3.6e-07 29.5 0.6 0.57 9.1 0.0 5.0 3 3 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ETS87200.1 - 5.1e-07 29.8 0.3 0.0013 18.6 0.0 3.4 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 ETS87200.1 - 9.5e-05 21.2 5.1 0.23 10.1 0.2 4.8 4 2 0 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 ETS87200.1 - 0.00038 20.3 2.9 0.69 9.9 0.0 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 ETS87200.1 - 0.0038 16.6 0.0 6.4 6.0 0.0 3.9 4 1 1 5 5 5 1 WD40-like domain NLE PF08154.12 ETS87200.1 - 0.0044 17.5 0.1 0.0099 16.4 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nbas_N PF15492.6 ETS87200.1 - 0.013 14.8 0.3 6.9 5.9 0.0 3.2 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal FAD_binding_9 PF08021.11 ETS87200.1 - 0.082 13.1 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Proteasome_A_N PF10584.9 ETS87200.1 - 0.22 11.2 2.1 12 5.7 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature MutS_V PF00488.21 ETS87201.1 - 3.3e-59 200.1 0.2 5.8e-59 199.3 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ETS87201.1 - 4.7e-25 88.9 1.6 5.5e-25 88.7 0.2 1.8 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 ETS87201.1 - 9.5e-08 32.4 0.3 3e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 ETS87201.1 - 1.1e-05 25.6 0.1 2.9e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV TTRAP PF14203.6 ETS87201.1 - 0.13 12.2 0.3 0.46 10.5 0.3 1.9 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein Glyco_transf_20 PF00982.21 ETS87202.1 - 5.5e-162 539.7 0.1 7.4e-162 539.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ETS87202.1 - 4.4e-41 140.5 0.0 7.2e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 ETS87202.1 - 0.0016 18.3 0.0 0.011 15.5 0.0 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase FAD_binding_3 PF01494.19 ETS87203.1 - 4.2e-80 269.6 0.0 5.6e-80 269.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS87203.1 - 2.8e-07 30.1 0.3 0.0063 15.8 0.2 2.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS87203.1 - 1e-05 25.0 0.4 0.0011 18.4 0.4 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS87203.1 - 0.00022 21.0 0.0 0.24 10.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ETS87203.1 - 0.00022 20.4 0.3 0.0088 15.1 0.2 2.8 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ETS87203.1 - 0.013 14.7 0.0 0.78 8.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 ETS87203.1 - 0.025 15.2 0.1 5.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ETS87203.1 - 0.042 14.1 0.0 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.6 ETS87203.1 - 0.067 13.2 0.3 0.44 10.5 0.3 2.2 1 1 0 1 1 1 0 FAD-NAD(P)-binding HET PF06985.11 ETS87204.1 - 5.9e-23 81.8 0.0 9.8e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 ETS87205.1 - 1.2e-20 74.0 0.0 1.6e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS87205.1 - 2.4e-10 40.2 0.0 3.4e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 ETS87205.1 - 0.16 10.9 0.1 0.78 8.6 0.0 1.8 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase PRAP PF15314.6 ETS87205.1 - 0.4 11.2 2.5 0.46 11.0 0.5 2.1 2 0 0 2 2 2 0 Proline-rich acidic protein 1, pregnancy-specific uterine zf-Di19 PF05605.12 ETS87206.1 - 0.17 12.2 0.8 15 5.9 0.0 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding TMF_TATA_bd PF12325.8 ETS87206.1 - 3.3 7.9 5.6 16 5.8 2.0 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding zf-H2C2_2 PF13465.6 ETS87206.1 - 5.8 7.5 5.8 97 3.7 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger double domain Peptidase_S8 PF00082.22 ETS87207.1 - 5.4e-24 85.0 0.0 9.2e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Subtilase family CorA PF01544.18 ETS87209.1 - 0.00034 20.0 12.3 0.022 14.1 12.3 2.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein FapA PF03961.13 ETS87209.1 - 0.14 10.7 3.1 0.2 10.2 3.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Sugarporin_N PF11471.8 ETS87209.1 - 0.17 11.8 1.3 0.33 10.9 1.3 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension HTH_ABP1_N PF18107.1 ETS87210.1 - 5.2e-15 54.9 0.4 5.2e-15 54.9 0.4 1.8 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 ETS87210.1 - 2.5e-07 30.6 0.3 1.5e-06 28.1 0.6 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain ABC_tran PF00005.27 ETS87211.1 - 5.1e-43 146.9 0.3 4.4e-23 82.3 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS87211.1 - 3.6e-36 125.2 25.3 8.7e-25 87.9 7.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ETS87211.1 - 1.2e-10 41.2 2.1 0.0003 20.3 0.1 3.9 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ETS87211.1 - 4.3e-07 30.0 4.0 2.1 8.1 0.0 4.3 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ETS87211.1 - 8.3e-06 25.5 5.3 0.042 13.6 0.2 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ETS87211.1 - 9.4e-05 22.7 1.4 0.022 15.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS87211.1 - 0.00013 22.4 0.2 0.31 11.4 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 ETS87211.1 - 0.00016 22.2 1.2 0.019 15.4 0.3 2.5 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 ETS87211.1 - 0.00061 18.9 0.4 0.19 10.8 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein SbcCD_C PF13558.6 ETS87211.1 - 0.0019 18.4 0.9 2 8.7 0.0 3.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 ETS87211.1 - 0.0025 18.0 0.0 0.34 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ETS87211.1 - 0.0047 17.5 0.1 3.5 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ETS87211.1 - 0.024 14.5 0.1 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 ETS87211.1 - 0.073 12.8 1.2 5 6.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ETS87211.1 - 0.1 12.3 0.8 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 ETS87211.1 - 0.1 12.1 0.1 19 4.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 ETS87211.1 - 0.12 12.5 0.1 3 8.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase dNK PF01712.19 ETS87211.1 - 0.18 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA PF00004.29 ETS87211.1 - 0.19 12.2 0.5 43 4.5 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ETS87211.1 - 0.24 11.1 0.8 21 4.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 ETS87211.1 - 0.28 11.1 2.0 20 5.1 0.6 2.6 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 ETS87211.1 - 0.81 9.2 3.1 4 7.0 0.1 2.9 3 1 0 3 3 3 0 AAA domain cobW PF02492.19 ETS87211.1 - 1.1 8.9 3.9 1.1 8.8 0.6 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AMP-binding PF00501.28 ETS87212.1 - 0 1807.6 0.0 9e-81 271.6 0.0 7.7 8 0 0 8 8 8 7 AMP-binding enzyme Condensation PF00668.20 ETS87212.1 - 0 1463.6 0.0 4.7e-50 170.6 0.0 12.2 12 0 0 12 12 12 11 Condensation domain PP-binding PF00550.25 ETS87212.1 - 9.2e-84 275.8 18.5 2e-13 50.5 0.1 9.0 8 0 0 8 8 8 7 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ETS87212.1 - 9.9e-30 103.4 0.3 5e-05 24.2 0.0 8.1 7 0 0 7 7 7 6 AMP-binding enzyme C-terminal domain Transferase PF02458.15 ETS87212.1 - 1.8e-06 26.9 1.5 8.3 4.9 0.0 6.5 7 0 0 7 7 7 4 Transferase family EF-hand_13 PF17958.1 ETS87212.1 - 0.0048 16.7 0.1 3.1 7.7 0.0 4.0 3 0 0 3 3 3 1 EF-hand domain DUF5122 PF17164.4 ETS87212.1 - 5 7.5 9.0 60 4.0 0.0 5.0 6 0 0 6 6 6 0 Domain of unknown function (DUF5122) beta-propeller Aminotran_4 PF01063.19 ETS87213.1 - 2.6e-21 76.5 0.0 3.2e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Peroxidase_2 PF01328.17 ETS87214.1 - 6.7e-41 140.9 0.0 8.9e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 K_trans PF02705.16 ETS87216.1 - 3.1e-184 613.4 14.8 3.7e-184 613.2 14.8 1.0 1 0 0 1 1 1 1 K+ potassium transporter WSC PF01822.19 ETS87217.1 - 5.2e-10 39.4 17.0 1.3e-06 28.5 12.6 2.9 2 1 0 2 2 2 2 WSC domain SpoVAD PF07451.11 ETS87217.1 - 0.086 11.5 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) WSC PF01822.19 ETS87218.1 - 1.3e-05 25.2 10.2 1.3e-05 25.2 10.2 2.7 2 0 0 2 2 2 1 WSC domain EcsC PF12787.7 ETS87219.1 - 0.11 12.2 0.1 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 EcsC protein family WSC PF01822.19 ETS87220.1 - 4.1e-09 36.5 11.6 1.7e-08 34.5 11.6 2.2 1 0 0 1 1 1 1 WSC domain UCH PF00443.29 ETS87222.1 - 1.9e-53 181.6 0.0 4.1e-53 180.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ETS87222.1 - 7.6e-27 94.7 1.0 6.7e-19 68.6 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pinin_SDK_memA PF04696.13 ETS87222.1 - 0.08 13.0 20.9 0.26 11.3 20.9 1.8 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region SRP-alpha_N PF04086.13 ETS87222.1 - 0.57 10.1 19.0 0.23 11.4 14.1 2.6 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Bud13 PF09736.9 ETS87222.1 - 2.4 8.5 18.8 16 5.9 17.5 2.5 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Peptidase_C98 PF15499.6 ETS87222.1 - 4.7 6.6 14.0 0.43 10.0 1.3 3.1 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase ALMT PF11744.8 ETS87222.1 - 4.7 5.9 5.0 7.2 5.3 5.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Borrelia_P83 PF05262.11 ETS87222.1 - 9 4.7 19.4 15 3.9 19.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Yos1 PF08571.10 ETS87223.1 - 8.5e-18 64.4 0.0 1.2e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.17 ETS87224.1 - 1.2e-41 143.4 17.6 1.7e-41 142.9 17.6 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family TraL PF07178.11 ETS87224.1 - 1 9.9 4.1 2.2 8.8 0.3 2.8 2 0 0 2 2 2 0 TraL protein PSD2 PF07624.11 ETS87226.1 - 0.074 12.8 0.6 9.7 6.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1585) Fungal_trans PF04082.18 ETS87227.1 - 1.6e-14 53.6 1.5 2.3e-14 53.0 1.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS87227.1 - 1.8e-07 31.1 9.6 2.8e-07 30.5 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS87228.1 - 1.3e-14 53.9 0.0 1.9e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS87228.1 - 5.5e-06 26.4 13.4 8.6e-06 25.8 13.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tannase PF07519.11 ETS87229.1 - 4.7e-100 335.7 0.5 6e-100 335.4 0.5 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Esterase PF00756.20 ETS87229.1 - 0.0057 16.3 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Putative esterase DUF2855 PF11017.8 ETS87230.1 - 8.8e-82 275.5 0.1 1e-81 275.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Inositol_P PF00459.25 ETS87232.1 - 3.2e-39 135.1 0.2 9.4e-39 133.5 0.2 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family FAD_binding_3 PF01494.19 ETS87233.1 - 1.4e-19 70.6 0.0 1.1e-13 51.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ETS87233.1 - 3e-10 39.8 0.1 7.8e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS87233.1 - 1.9e-08 34.3 2.0 5.1e-05 23.0 0.4 3.0 1 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS87233.1 - 3.9e-06 27.3 0.1 5.5e-05 23.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS87233.1 - 7.9e-05 22.8 0.1 0.00089 19.4 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 ETS87233.1 - 0.00016 21.0 0.1 0.00029 20.2 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 ETS87233.1 - 0.0014 17.8 0.0 0.0091 15.1 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 ETS87233.1 - 0.0093 14.9 0.0 0.13 11.1 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 ETS87233.1 - 0.011 14.9 0.1 0.018 14.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 ETS87233.1 - 0.031 13.6 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase ApbA PF02558.16 ETS87233.1 - 0.033 13.9 0.1 0.092 12.4 0.1 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Tir_receptor_N PF07490.11 ETS87233.1 - 0.044 13.6 0.1 0.12 12.1 0.0 1.6 1 1 1 2 2 2 0 Translocated intimin receptor (Tir) N-terminus FAD_oxidored PF12831.7 ETS87233.1 - 0.048 13.0 0.2 0.17 11.2 0.2 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 ETS87233.1 - 0.079 12.8 0.3 0.58 10.0 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 ETS87233.1 - 0.08 12.0 0.2 0.13 11.4 0.2 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 ETS87233.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain CoA_transf_3 PF02515.17 ETS87233.1 - 0.11 11.5 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 CoA-transferase family III NAD_binding_7 PF13241.6 ETS87233.1 - 0.12 12.8 0.0 0.32 11.5 0.0 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 ETS87233.1 - 0.19 12.0 0.1 0.34 11.1 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 ETS87233.1 - 0.22 12.2 0.4 0.44 11.2 0.2 1.7 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent HsbA PF12296.8 ETS87234.1 - 9.1e-25 87.4 11.5 9.1e-25 87.4 11.5 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A SNF5 PF04855.12 ETS87235.1 - 5.8e-90 301.2 0.0 7.7e-90 300.8 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 ETS87235.1 - 1.9e-05 24.2 2.7 4.7e-05 22.9 2.7 1.7 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 ETS87235.1 - 0.47 10.2 4.8 0.42 10.4 1.5 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Mito_carr PF00153.27 ETS87236.1 - 5.1e-45 151.3 7.9 2e-17 62.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein vATP-synt_E PF01991.18 ETS87236.1 - 0.67 9.3 2.4 0.95 8.8 2.4 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Clr5 PF14420.6 ETS87237.1 - 2e-20 72.8 0.8 3.4e-20 72.0 0.8 1.4 1 0 0 1 1 1 1 Clr5 domain CBS PF00571.28 ETS87238.1 - 1.1e-06 28.9 0.0 0.065 13.7 0.0 3.1 2 1 0 2 2 2 2 CBS domain DUF4165 PF13752.6 ETS87238.1 - 0.08 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4165) Epimerase PF01370.21 ETS87240.1 - 2.9e-19 69.5 0.0 3.8e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ETS87240.1 - 1e-09 37.9 0.0 1.6e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 ETS87240.1 - 1.5e-05 24.6 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ETS87240.1 - 0.00013 21.1 0.0 0.0014 17.7 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 ETS87240.1 - 0.033 14.5 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 ETS87240.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase F_actin_cap_B PF01115.17 ETS87241.1 - 5e-103 343.8 0.0 5.8e-103 343.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 ETS87241.1 - 0.064 12.7 0.1 0.42 10.0 0.1 2.2 2 1 1 3 3 3 0 F-actin capping protein alpha subunit Ferric_reduct PF01794.19 ETS87242.1 - 7e-20 71.4 9.9 7e-20 71.4 9.9 2.3 3 1 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ETS87242.1 - 3.5e-10 40.2 0.0 7.9e-06 26.1 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ETS87242.1 - 1.3e-07 31.7 0.0 3.1e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 ETS87242.1 - 0.0047 17.5 0.0 0.0078 16.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain GST_N PF02798.20 ETS87244.1 - 2.6e-09 37.3 0.0 1.1e-08 35.3 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ETS87244.1 - 2.1e-07 31.2 0.0 4.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ETS87244.1 - 9e-06 25.8 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ETS87244.1 - 0.00042 20.5 0.0 0.00063 19.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ETS87244.1 - 0.00052 20.0 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ETS87244.1 - 0.0056 17.0 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DSX_dimer PF08828.10 ETS87244.1 - 0.097 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Doublesex dimerisation domain ADC PF06314.11 ETS87245.1 - 0.0021 17.6 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Fungal_trans PF04082.18 ETS87246.1 - 5.8e-14 51.7 0.2 9e-14 51.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS87246.1 - 7e-09 35.7 8.3 1.5e-08 34.6 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ETS87248.1 - 7e-48 163.3 42.1 7e-48 163.3 42.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS87248.1 - 4.8e-15 55.4 14.6 4.8e-15 55.4 14.6 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 ETS87248.1 - 7.1e-09 35.4 8.9 7.1e-09 35.4 8.9 2.4 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 ETS87248.1 - 1.9e-06 26.6 4.3 1.9e-06 26.6 4.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 ETS87248.1 - 3.5e-05 22.3 6.2 3.5e-05 22.3 6.2 2.2 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family BT1 PF03092.16 ETS87248.1 - 0.003 15.9 0.4 0.0045 15.3 0.4 1.2 1 0 0 1 1 1 1 BT1 family SCAB-PH PF17684.1 ETS87248.1 - 0.18 12.1 0.1 0.37 11.1 0.1 1.4 1 0 0 1 1 1 0 PH domain of plant-specific actin-binding protein DUF5378 PF17349.2 ETS87248.1 - 1 8.6 6.6 0.32 10.3 0.6 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5378) Fungal_trans PF04082.18 ETS87249.1 - 5e-12 45.4 0.0 8.4e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CaATP_NAI PF12515.8 ETS87249.1 - 5.9 6.6 6.1 17 5.2 0.4 3.1 3 0 0 3 3 3 0 Ca2+-ATPase N terminal autoinhibitory domain HrpF PF06266.12 ETS87250.1 - 0.096 13.0 2.8 0.37 11.1 0.1 3.0 2 1 1 3 3 3 0 HrpF protein DUF4618 PF15397.6 ETS87250.1 - 1.2 8.5 7.8 0.37 10.2 1.5 2.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4618) T3SSipB PF16535.5 ETS87250.1 - 1.6 9.2 15.3 1.5 9.3 0.4 3.6 2 1 1 3 3 3 0 Type III cell invasion protein SipB AAA_23 PF13476.6 ETS87250.1 - 2.3 8.7 11.2 11 6.5 0.3 2.2 1 1 1 2 2 2 0 AAA domain adh_short PF00106.25 ETS87251.1 - 2.7e-21 75.9 0.0 2e-18 66.5 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS87251.1 - 3e-09 36.8 0.1 2.6e-08 33.7 0.1 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS87251.1 - 1.1e-06 28.7 0.1 2.2e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 KR domain ATP-grasp PF02222.22 ETS87251.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 ATP-grasp domain Sulfatase PF00884.23 ETS87252.1 - 1.2e-61 208.8 0.0 1.8e-61 208.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 ETS87252.1 - 0.0027 17.4 1.3 0.025 14.2 1.3 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 ETS87252.1 - 0.008 16.4 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) MFS_1 PF07690.16 ETS87253.1 - 1.7e-44 152.2 33.9 1.7e-44 152.2 33.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS87253.1 - 1.2e-10 40.8 29.8 7.1e-10 38.3 11.6 3.7 3 2 0 3 3 3 2 Sugar (and other) transporter Folate_carrier PF01770.18 ETS87253.1 - 0.028 13.2 0.7 0.44 9.2 0.2 2.3 2 0 0 2 2 2 0 Reduced folate carrier Phage_holin_3_2 PF04550.12 ETS87253.1 - 3.2 8.4 8.1 6.8 7.3 1.4 3.5 3 0 0 3 3 3 0 Phage holin family 2 DUF1275 PF06912.11 ETS87254.1 - 4.2e-50 170.4 15.6 4.9e-50 170.1 15.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF3792 PF12670.7 ETS87254.1 - 0.032 14.4 10.8 0.89 9.7 0.5 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF3792) Cupin_1 PF00190.22 ETS87255.1 - 2.6e-40 137.5 0.0 5.6e-21 74.7 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 ETS87255.1 - 1.2e-27 95.4 1.2 1.3e-14 53.6 0.3 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 ETS87255.1 - 4.2e-08 32.8 0.1 0.00069 19.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 ETS87255.1 - 2.9e-07 30.5 0.3 0.0013 18.6 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 ETS87255.1 - 0.00084 19.3 0.0 0.024 14.6 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_7 PF12973.7 ETS87255.1 - 0.018 14.9 0.4 0.25 11.3 0.1 2.6 2 1 0 2 2 2 0 ChrR Cupin-like domain ARD PF03079.14 ETS87255.1 - 0.033 14.4 0.1 4.2 7.5 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family 3-HAO PF06052.12 ETS87255.1 - 0.085 12.5 0.0 0.61 9.7 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Sulfate_transp PF00916.20 ETS87256.1 - 1.5e-85 287.3 15.8 2e-85 286.9 15.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ETS87256.1 - 5.4e-06 26.0 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ETS87256.1 - 0.0034 17.8 15.2 0.011 16.1 2.5 2.8 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily 2-Hacid_dh_C PF02826.19 ETS87257.1 - 9.6e-56 187.9 0.1 2.6e-55 186.5 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ETS87257.1 - 1.1e-31 109.3 0.0 1.5e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ETS87257.1 - 0.00014 22.1 0.2 0.00044 20.5 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 ETS87257.1 - 0.00092 18.8 0.1 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 ETS87257.1 - 0.019 15.0 0.1 0.05 13.7 0.1 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 ETS87257.1 - 0.068 12.5 0.9 1.6 7.9 0.9 2.2 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Rossmann-like PF10727.9 ETS87257.1 - 0.081 12.8 0.4 1.4 8.8 0.0 2.5 2 1 0 2 2 2 0 Rossmann-like domain FMO-like PF00743.19 ETS87258.1 - 1.3e-14 53.6 0.0 9.2e-14 50.7 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ETS87258.1 - 9.3e-09 35.0 0.0 4.2e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS87258.1 - 3.3e-07 29.8 0.0 1.1e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS87258.1 - 5e-05 22.6 0.0 0.00016 21.0 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ETS87258.1 - 0.00097 19.3 0.4 0.009 16.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ETS87258.1 - 0.015 14.9 0.0 0.45 10.0 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS87258.1 - 0.017 15.1 0.8 1.5 8.8 0.1 3.3 2 1 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.16 ETS87259.1 - 2.4e-31 108.9 33.4 4.8e-31 108.0 33.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Dicty_CAR PF05462.11 ETS87260.1 - 7.4e-10 38.4 9.4 7.4e-10 38.4 9.4 1.4 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 ETS87260.1 - 2.2e-06 27.2 4.4 2.9e-06 26.8 4.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 ETS87260.1 - 2.1e-05 24.4 14.1 3.4e-05 23.7 14.1 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 DUF2576 PF10845.8 ETS87260.1 - 0.13 11.8 0.0 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Abhydrolase_3 PF07859.13 ETS87261.1 - 8.2e-46 156.5 0.0 2.1e-45 155.2 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 ETS87261.1 - 2.1e-05 23.6 0.3 0.0001 21.4 0.3 1.9 1 1 0 1 1 1 1 Carboxylesterase family DAP3 PF10236.9 ETS87262.1 - 1.4e-85 287.2 0.0 1.7e-85 286.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 ETS87262.1 - 0.023 15.1 0.1 0.055 13.9 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain DSBA PF01323.20 ETS87262.1 - 0.042 13.6 0.1 0.081 12.7 0.1 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain RRS1 PF04939.12 ETS87263.1 - 3e-48 163.7 1.9 3.4e-48 163.6 1.9 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGAP PF00620.27 ETS87264.1 - 2.1e-28 99.1 0.0 3.2e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Prenyltrans PF00432.21 ETS87265.1 - 8.1e-58 191.8 5.4 1.3e-12 47.2 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 ETS87265.1 - 5.3e-07 29.0 0.0 0.1 11.7 0.0 3.8 2 1 2 4 4 4 4 Squalene-hopene cyclase N-terminal domain MFS_1 PF07690.16 ETS87266.1 - 4.4e-18 65.3 38.2 4.4e-18 65.3 38.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS87266.1 - 0.004 16.1 13.4 0.004 16.1 13.4 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter DUF4387 PF14330.6 ETS87268.1 - 1.6e-35 121.7 0.0 5.1e-35 120.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4387) AtuA PF07287.11 ETS87268.1 - 2.4e-13 49.5 0.0 5.6e-13 48.3 0.0 1.5 1 1 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA MFS_1 PF07690.16 ETS87269.1 - 2.3e-31 109.0 26.1 2.3e-31 109.0 26.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS87269.1 - 0.00082 18.8 22.2 0.074 12.3 22.2 2.2 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB VEGFR-2_TMD PF17988.1 ETS87269.1 - 0.61 9.6 4.6 3.3 7.2 4.6 2.3 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain MCM PF00493.23 ETS87270.1 - 3.2e-104 346.9 0.0 5.1e-104 346.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ETS87270.1 - 4.2e-31 107.4 1.1 7.5e-31 106.6 1.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ETS87270.1 - 3.6e-20 72.2 0.7 9.9e-20 70.8 0.7 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ETS87270.1 - 1.7e-17 63.9 1.3 4.2e-17 62.6 1.3 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ETS87270.1 - 1.5e-07 31.0 0.0 1.5e-05 24.5 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ETS87270.1 - 3e-06 27.3 0.0 1.4e-05 25.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 ETS87270.1 - 0.00058 19.7 0.3 0.011 15.5 0.3 2.8 2 0 0 2 2 2 1 AAA lid domain Mg_chelatase_C PF13335.6 ETS87270.1 - 0.0085 16.7 0.6 0.053 14.2 0.5 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 ETS87270.1 - 0.014 15.2 0.0 0.051 13.4 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 ETS87271.1 - 4.5e-56 188.9 0.0 4.7e-43 146.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 ETS87271.1 - 1.7e-28 98.9 0.2 3.5e-28 97.8 0.2 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 ETS87271.1 - 6.2e-12 45.1 0.1 1.7e-07 30.9 0.0 2.9 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 ETS87271.1 - 1.6e-10 41.6 4.2 0.00024 21.5 0.1 5.2 3 2 1 4 4 4 2 AAA ATPase domain NACHT PF05729.12 ETS87271.1 - 5e-07 29.8 0.5 0.00058 19.8 0.0 3.7 4 0 0 4 4 4 1 NACHT domain AAA_2 PF07724.14 ETS87271.1 - 1.5e-05 25.2 0.0 0.23 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 ETS87271.1 - 1.9e-05 24.4 0.0 0.015 15.1 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 ETS87271.1 - 2.1e-05 24.1 0.0 0.00066 19.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 ETS87271.1 - 5.5e-05 23.4 1.0 2.2 8.6 0.1 3.9 2 2 1 3 3 3 2 AAA domain TsaE PF02367.17 ETS87271.1 - 5.8e-05 23.1 0.0 0.078 13.0 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 ETS87271.1 - 0.00033 20.9 0.0 0.31 11.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ETS87271.1 - 0.00063 20.3 0.0 0.79 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 ETS87271.1 - 0.0007 19.6 0.0 1.5 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 ETS87271.1 - 0.0019 17.5 0.0 1.8 7.7 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain Zeta_toxin PF06414.12 ETS87271.1 - 0.002 17.5 0.1 0.52 9.6 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin PEX-2N PF09263.10 ETS87271.1 - 0.0026 18.0 0.3 1.9 8.9 0.0 2.7 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal IstB_IS21 PF01695.17 ETS87271.1 - 0.0055 16.5 0.1 3.9 7.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.14 ETS87271.1 - 0.0065 16.5 0.1 3.1 7.8 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ETS87271.1 - 0.017 15.5 0.0 9.5 6.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 ETS87271.1 - 0.018 14.4 0.7 1 8.7 0.1 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 ETS87271.1 - 0.02 14.6 0.0 0.94 9.2 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 ETS87271.1 - 0.033 13.4 0.1 6.3 5.9 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.26 ETS87271.1 - 0.072 12.8 0.0 2.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 ETS87271.1 - 0.076 12.6 2.8 8.9 5.8 0.2 3.3 2 2 0 3 3 3 0 AAA domain Cytidylate_kin2 PF13189.6 ETS87271.1 - 0.082 13.0 0.0 5.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family Pkinase PF00069.25 ETS87272.1 - 9.4e-53 179.3 0.0 1.2e-52 178.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS87272.1 - 6.1e-39 133.8 0.0 8.7e-39 133.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS87272.1 - 0.00075 18.9 0.0 0.0046 16.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ETS87272.1 - 0.0015 18.5 0.0 0.035 14.0 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ETS87272.1 - 0.0041 16.0 0.0 0.0075 15.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ETS87272.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 ETS87272.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Haspin_kinase PF12330.8 ETS87272.1 - 0.18 10.7 0.0 0.93 8.4 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain PRIMA1 PF16101.5 ETS87272.1 - 0.49 10.4 2.9 1.3 9.0 2.9 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 ETS87272.1 - 2 7.8 4.5 5 6.5 4.5 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Telomere_reg-2 PF10193.9 ETS87273.1 - 2.2e-33 115.0 0.0 7.9e-33 113.2 0.0 2.0 2 0 0 2 2 2 1 Telomere length regulation protein ThiF PF00899.21 ETS87274.1 - 5.2e-65 219.2 0.0 8.2e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 ETS87274.1 - 5.6e-27 93.7 0.1 9.5e-27 93.0 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 ETS87274.1 - 0.0011 19.0 0.0 0.003 17.6 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 ETS87274.1 - 0.036 14.6 0.0 0.07 13.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 ETS87274.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 ETS87274.1 - 0.12 11.9 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Complex1_49kDa PF00346.19 ETS87276.1 - 6.2e-123 409.2 0.0 8.5e-123 408.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 ETS87276.1 - 0.0068 15.4 0.0 0.013 14.5 0.0 1.4 1 1 0 1 1 1 1 Nickel-dependent hydrogenase Macoilin PF09726.9 ETS87277.1 - 3 6.3 13.4 4.3 5.8 13.4 1.3 1 0 0 1 1 1 0 Macoilin family ABM PF03992.16 ETS87278.1 - 0.11 12.6 0.1 0.33 11.1 0.1 1.8 1 1 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Cys_Met_Meta_PP PF01053.20 ETS87279.1 - 1.1e-21 76.8 0.0 1.8e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ETS87279.1 - 3.9e-06 26.3 0.0 6.2e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II VTC PF09359.10 ETS87280.1 - 1.9e-95 319.4 1.1 2.2e-95 319.2 0.1 1.6 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 ETS87280.1 - 3e-13 50.5 11.9 1.1e-05 25.5 0.1 4.2 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 ETS87280.1 - 4.7e-13 49.4 1.2 9.2e-13 48.4 1.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Ank_2 PF12796.7 ETS87281.1 - 0.029 15.0 0.0 0.094 13.3 0.0 1.9 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) SDA1 PF05285.12 ETS87281.1 - 0.8 9.1 5.6 1.4 8.2 5.6 1.4 1 0 0 1 1 1 0 SDA1 Hexokinase_2 PF03727.16 ETS87282.1 - 2.5e-83 279.2 0.0 3.1e-83 278.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ETS87282.1 - 3.5e-62 209.9 0.0 7.8e-62 208.7 0.0 1.5 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 ETS87283.1 - 0.00061 19.7 0.1 0.00085 19.3 0.1 1.2 1 0 0 1 1 1 1 Hexokinase DUF2884 PF11101.8 ETS87283.1 - 0.029 13.9 0.0 0.033 13.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Aldolase_II PF00596.21 ETS87283.1 - 0.059 13.3 0.1 0.062 13.2 0.1 1.1 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain Ribophorin_I PF04597.14 ETS87284.1 - 5.8e-148 493.7 0.2 6.8e-148 493.5 0.2 1.0 1 0 0 1 1 1 1 Ribophorin I Pil1 PF13805.6 ETS87285.1 - 5.2e-102 340.9 6.8 9e-102 340.1 6.8 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 BAR_3 PF16746.5 ETS87285.1 - 0.045 13.4 2.7 0.074 12.7 2.7 1.4 1 0 0 1 1 1 0 BAR domain of APPL family FAD_binding_3 PF01494.19 ETS87286.1 - 4.2e-25 88.7 0.0 3.2e-24 85.8 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ETS87286.1 - 7.6e-06 25.2 0.5 0.00042 19.5 0.1 2.8 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ETS87286.1 - 0.0018 17.5 0.0 0.0043 16.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS87286.1 - 0.0041 16.8 0.1 0.065 12.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS87286.1 - 0.011 15.9 0.1 0.037 14.2 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ETS87286.1 - 0.025 14.6 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding SE PF08491.10 ETS87286.1 - 0.034 13.2 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.17 ETS87286.1 - 0.034 13.4 0.0 0.07 12.4 0.0 1.5 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.6 ETS87286.1 - 0.052 12.7 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) RNA_pol_A_bac PF01000.26 ETS87287.1 - 5.3e-24 84.7 0.0 1.2e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 ETS87287.1 - 6.1e-20 70.4 0.0 8.4e-20 70.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain WASH-7_N PF14745.6 ETS87288.1 - 0.014 13.9 0.1 0.021 13.3 0.1 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal MIT PF04212.18 ETS87288.1 - 0.016 15.3 0.1 8.4 6.6 0.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Chitin_synth_1 PF01644.17 ETS87290.1 - 1.2e-64 217.2 0.0 2e-64 216.5 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 ETS87290.1 - 2.3e-28 99.1 0.1 4.4e-24 85.0 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 ETS87290.1 - 4.4e-24 84.2 0.0 8.4e-24 83.3 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 ETS87290.1 - 2.8e-11 43.7 0.0 2.8e-11 43.7 0.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ETS87290.1 - 0.00063 19.7 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 BTB PF00651.31 ETS87290.1 - 0.0087 16.3 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Glyco_hydro_2_C PF02836.17 ETS87291.1 - 4.6e-12 45.7 0.0 1.2e-10 41.0 0.0 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 ETS87291.1 - 1.4e-09 38.1 0.2 1.4e-08 34.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 ETS87291.1 - 5.5e-08 33.5 0.0 1.2e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 MCM PF00493.23 ETS87292.1 - 2.8e-100 334.0 0.0 4.3e-100 333.4 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ETS87292.1 - 2.5e-39 134.0 0.8 4.7e-39 133.1 0.8 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ETS87292.1 - 5.7e-30 103.6 3.2 1.4e-29 102.4 3.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ETS87292.1 - 2.5e-18 66.6 0.1 1.1e-17 64.5 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 ETS87292.1 - 2.1e-06 27.8 0.0 1.5e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ETS87292.1 - 2.4e-05 23.8 0.0 0.00089 18.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 ETS87292.1 - 0.0015 18.4 0.0 0.0052 16.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Oberon_cc PF16312.5 ETS87292.1 - 0.13 12.2 3.1 0.35 10.8 3.1 1.7 1 0 0 1 1 1 0 Coiled-coil region of Oberon Clat_adaptor_s PF01217.20 ETS87293.1 - 2.8e-15 56.5 1.6 7.1e-15 55.2 1.6 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Sua5_yciO_yrdC PF01300.18 ETS87294.1 - 1.3e-52 177.9 0.0 2.3e-52 177.1 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 ETS87294.1 - 3.2e-32 111.9 0.1 5e-32 111.3 0.1 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding COG4 PF08318.12 ETS87295.1 - 2.1e-125 418.2 0.0 2.9e-125 417.8 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein HSCB_C PF07743.13 ETS87295.1 - 0.7 10.4 7.3 1.2 9.7 1.1 3.4 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain THOC7 PF05615.13 ETS87296.1 - 3.4e-38 130.9 6.8 6.6e-38 130.0 0.4 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 HMMR_N PF15905.5 ETS87296.1 - 0.034 13.6 3.4 0.05 13.1 3.4 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF5454 PF17535.2 ETS87296.1 - 0.094 12.1 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5454) Med21 PF11221.8 ETS87296.1 - 0.4 10.9 12.7 0.081 13.2 1.1 2.9 2 1 1 3 3 3 0 Subunit 21 of Mediator complex NYD-SP28_assoc PF14775.6 ETS87296.1 - 0.59 10.3 2.7 12 6.1 0.1 2.7 2 0 0 2 2 2 0 Sperm tail C-terminal domain Lipoprotein_20 PF13942.6 ETS87296.1 - 0.87 9.5 7.7 0.71 9.8 0.9 2.2 1 1 0 2 2 2 0 YfhG lipoprotein OmpH PF03938.14 ETS87296.1 - 1 9.7 6.6 3.5 7.9 6.6 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 ETS87296.1 - 3.1 7.7 7.0 10 6.0 0.1 3.3 2 1 1 3 3 3 0 Septum formation initiator ZapB PF06005.12 ETS87296.1 - 5.2 7.6 10.2 1 9.9 2.7 2.7 1 1 1 2 2 2 0 Cell division protein ZapB FUSC PF04632.12 ETS87296.1 - 5.4 5.4 9.0 7.1 5.0 9.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TBCA PF02970.16 ETS87297.1 - 2.2e-23 82.4 7.7 3.4e-23 81.8 7.8 1.3 1 1 0 1 1 1 1 Tubulin binding cofactor A Csm1_N PF18504.1 ETS87297.1 - 0.029 14.7 8.0 0.049 14.0 1.4 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain Fib_alpha PF08702.10 ETS87297.1 - 0.066 13.4 3.0 0.082 13.1 3.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1910 PF08928.10 ETS87297.1 - 0.11 12.5 3.5 0.23 11.5 3.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) RasGAP_C PF03836.15 ETS87297.1 - 0.21 11.7 4.8 0.31 11.2 2.8 1.9 1 1 1 2 2 2 0 RasGAP C-terminus DUF2408 PF10303.9 ETS87297.1 - 0.33 11.5 3.5 0.41 11.2 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) ABC_tran_CTD PF16326.5 ETS87297.1 - 0.39 11.0 11.9 0.75 10.1 3.3 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain Dynamin_N PF00350.23 ETS87298.1 - 1.8e-31 109.5 0.6 5.2e-31 108.0 0.6 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 ETS87298.1 - 1.2e-24 87.1 0.1 3e-24 85.7 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 ETS87298.1 - 0.00026 21.1 0.2 0.0088 16.1 0.3 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 ETS87298.1 - 0.0025 17.6 0.4 0.0088 15.8 0.0 2.1 3 0 0 3 3 3 1 AAA ATPase domain Roc PF08477.13 ETS87298.1 - 0.12 12.6 0.1 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Methyltransf_23 PF13489.6 ETS87299.1 - 1.1e-23 83.9 0.0 1.7e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS87299.1 - 3.1e-11 43.3 0.0 5.5e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS87299.1 - 3.8e-10 40.3 0.0 8.7e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS87299.1 - 2e-07 31.6 0.0 5.1e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS87299.1 - 1.5e-06 28.7 0.0 2.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS87299.1 - 0.0021 17.7 0.0 0.0043 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 ETS87299.1 - 0.0055 16.1 0.0 0.041 13.2 0.0 2.1 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 ETS87299.1 - 0.0064 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 ETS87299.1 - 0.0085 15.5 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 ETS87299.1 - 0.069 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain MetW PF07021.12 ETS87299.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW COX17 PF05051.13 ETS87300.1 - 5.4e-21 74.7 7.2 6.6e-21 74.4 7.2 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) adh_short PF00106.25 ETS87301.1 - 9.9e-53 178.5 1.5 1.3e-52 178.2 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS87301.1 - 8.1e-49 166.3 2.8 1.3e-48 165.7 2.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS87301.1 - 2.3e-11 43.9 0.5 4.7e-11 42.9 0.5 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS87301.1 - 0.002 17.6 0.2 0.0043 16.5 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 ETS87301.1 - 0.0027 17.0 0.1 0.041 13.2 0.1 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1482 PF07358.11 ETS87301.1 - 0.035 14.0 0.1 0.11 12.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1482) Cbl_N2 PF02761.14 ETS87301.1 - 0.056 14.2 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, EF hand-like domain GDP_Man_Dehyd PF16363.5 ETS87301.1 - 0.12 11.7 0.1 0.85 8.9 0.1 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase FtsK_SpoIIIE PF01580.18 ETS87301.1 - 0.19 11.1 0.5 1.8 7.9 0.0 2.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family CBM_4_9 PF02018.17 ETS87302.1 - 7.5e-05 23.0 0.0 0.00011 22.4 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain Cutinase PF01083.22 ETS87304.1 - 5.9e-50 169.7 9.2 6.7e-50 169.5 9.2 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 ETS87304.1 - 3.3e-05 23.5 0.5 6.5e-05 22.6 0.4 1.6 1 1 1 2 2 2 1 PE-PPE domain Abhydrolase_6 PF12697.7 ETS87304.1 - 0.081 13.5 0.5 0.096 13.3 0.5 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DIOX_N PF14226.6 ETS87305.1 - 8.1e-21 75.0 0.0 2.8e-20 73.2 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS87305.1 - 5.6e-11 42.8 0.0 1e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 ETS87306.1 - 2.7e-30 105.5 27.6 2.7e-30 105.5 27.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily SGTA_dimer PF16546.5 ETS87307.1 - 1.2e-26 92.2 0.2 2.3e-26 91.4 0.2 1.4 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 ETS87307.1 - 9.6e-13 47.2 5.4 0.0021 18.1 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 ETS87307.1 - 5.8e-12 44.9 4.2 0.0028 17.4 0.1 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 ETS87307.1 - 4.9e-09 35.7 3.3 6.2e-05 22.6 0.5 3.2 2 1 1 3 3 3 3 TPR repeat TPR_16 PF13432.6 ETS87307.1 - 1.7e-08 35.0 11.8 0.00014 22.4 7.8 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 ETS87307.1 - 8e-07 29.4 9.1 0.12 13.3 2.7 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 ETS87307.1 - 9.5e-06 25.6 0.4 0.029 14.7 0.2 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 ETS87307.1 - 2.7e-05 24.6 4.3 0.0056 17.2 1.2 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ETS87307.1 - 3.2e-05 23.8 3.0 0.54 10.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 ETS87307.1 - 5e-05 23.4 2.7 0.0018 18.4 0.7 2.6 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ETS87307.1 - 8.8e-05 22.7 3.7 0.00025 21.2 0.9 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat STI1 PF17830.1 ETS87307.1 - 0.00012 21.9 12.1 0.00082 19.3 7.2 2.4 2 0 0 2 2 2 1 STI1 domain TPR_7 PF13176.6 ETS87307.1 - 0.00059 19.7 0.6 2.1 8.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat XPC-binding PF09280.11 ETS87307.1 - 0.0038 16.9 6.8 0.0055 16.4 5.6 1.8 2 0 0 2 2 2 1 XPC-binding domain BTAD PF03704.17 ETS87307.1 - 0.004 17.6 2.6 1.6 9.2 1.0 2.2 1 1 1 2 2 2 2 Bacterial transcriptional activator domain TPR_6 PF13174.6 ETS87307.1 - 0.037 14.7 4.2 3.8 8.3 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 ETS87307.1 - 0.04 13.8 5.7 0.26 11.2 0.8 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 ETS87307.1 - 0.086 12.9 1.8 1.1 9.3 0.1 3.1 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain GerD PF17898.1 ETS87307.1 - 0.12 12.3 1.8 0.56 10.2 0.8 2.2 2 0 0 2 2 2 0 Spore germination GerD central core domain Acetyltransf_2 PF00797.17 ETS87308.1 - 5.4e-35 121.3 0.0 1.2e-34 120.2 0.0 1.6 1 1 0 1 1 1 1 N-acetyltransferase ABC_tran PF00005.27 ETS87309.1 - 7e-31 107.6 0.2 1.7e-30 106.3 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 ETS87309.1 - 7e-24 84.9 2.5 7e-24 84.9 2.5 2.4 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.19 ETS87309.1 - 0.00021 20.8 0.0 0.0015 18.1 0.0 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ETS87309.1 - 0.00098 18.9 0.0 0.006 16.3 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain PAM2 PF07145.15 ETS87309.1 - 0.0017 17.9 0.0 0.0035 16.9 0.0 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region AAA_30 PF13604.6 ETS87309.1 - 0.027 14.2 0.1 0.087 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain Ion_trans PF00520.31 ETS87309.1 - 0.028 13.7 0.0 0.077 12.2 0.0 1.8 1 0 0 1 1 1 0 Ion transport protein RsgA_GTPase PF03193.16 ETS87309.1 - 0.033 14.1 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 ETS87309.1 - 0.044 13.6 1.6 0.067 13.0 0.1 2.1 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 ETS87309.1 - 0.052 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 ETS87309.1 - 0.067 13.0 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 ETS87309.1 - 0.17 11.5 0.1 0.46 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain SNARE_assoc PF09335.11 ETS87309.1 - 6.7 7.2 7.8 6.4 7.3 2.5 3.4 3 1 0 3 3 3 0 SNARE associated Golgi protein RINGv PF12906.7 ETS87310.1 - 3.2e-05 24.0 5.7 5.3e-05 23.3 5.7 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 ETS87310.1 - 0.00031 20.8 3.8 0.00061 19.9 3.8 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 ETS87310.1 - 0.02 15.3 6.6 0.032 14.6 6.6 1.3 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 ETS87310.1 - 0.06 13.4 1.1 0.1 12.7 1.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 ETS87310.1 - 0.16 11.7 4.0 0.28 11.0 4.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 ETS87310.1 - 0.49 10.3 3.6 0.9 9.4 3.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 ETS87310.1 - 3 7.8 5.1 4.7 7.2 5.1 1.3 1 0 0 1 1 1 0 PHD-finger zf-rbx1 PF12678.7 ETS87310.1 - 3.5 8.0 5.5 7.4 7.0 5.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Thaumatin PF00314.17 ETS87311.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.5 2 0 0 2 2 2 0 Thaumatin family Ank_2 PF12796.7 ETS87313.1 - 2.3e-48 162.7 0.6 3.7e-13 49.9 0.0 4.7 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS87313.1 - 3.6e-29 97.6 0.0 0.0028 18.0 0.1 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 ETS87313.1 - 1.4e-24 85.4 0.0 0.00027 21.3 0.4 7.7 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 ETS87313.1 - 1.4e-23 82.6 1.3 8.2e-07 29.2 0.0 6.6 3 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS87313.1 - 1.2e-19 70.4 0.7 0.00036 21.0 0.0 6.9 3 1 4 7 7 7 4 Ankyrin repeats (many copies) HET PF06985.11 ETS87313.1 - 1.4e-11 45.0 8.5 3.4e-10 40.4 2.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 ETS87313.1 - 3.1e-08 33.7 0.1 9.1e-08 32.2 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS87313.1 - 5.4e-05 23.6 0.1 0.00026 21.4 0.1 2.2 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 ETS87313.1 - 0.0097 16.3 0.0 0.028 14.8 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 ETS87313.1 - 0.058 13.7 0.0 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Annexin PF00191.20 ETS87314.1 - 4.2e-71 235.0 2.0 4e-20 71.6 0.0 4.3 4 1 0 4 4 4 4 Annexin DUF3574 PF12098.8 ETS87314.1 - 0.051 13.4 0.4 9 6.1 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3574) ABC_tran PF00005.27 ETS87315.1 - 1.1e-45 155.5 0.0 1e-26 94.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ETS87315.1 - 4.5e-36 124.9 28.7 1.3e-18 67.7 15.1 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 ETS87315.1 - 1.8e-14 53.7 0.1 0.00022 20.8 0.0 3.9 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ETS87315.1 - 1.1e-06 29.3 0.5 0.00054 20.5 0.3 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ETS87315.1 - 2.3e-06 27.9 0.0 0.099 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ETS87315.1 - 4.8e-06 26.2 2.7 0.039 13.7 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ETS87315.1 - 2.5e-05 24.7 0.8 0.22 11.9 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 ETS87315.1 - 2.5e-05 24.2 0.0 0.051 13.4 0.0 3.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ETS87315.1 - 0.00012 22.1 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 ETS87315.1 - 0.00014 21.8 1.1 0.1 12.5 0.1 3.5 3 1 0 3 3 3 1 NACHT domain MMR_HSR1 PF01926.23 ETS87315.1 - 0.0031 17.6 0.0 0.37 10.9 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 ETS87315.1 - 0.013 15.0 0.2 0.22 11.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ETS87315.1 - 0.043 13.5 0.2 9.4 5.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ETS87315.1 - 0.049 13.1 0.3 11 5.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 ETS87315.1 - 0.075 12.1 1.4 5.7 5.9 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 ETS87315.1 - 0.09 12.9 2.5 0.17 12.0 0.2 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 ETS87315.1 - 0.12 12.5 0.0 24 5.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ETS87315.1 - 0.14 11.9 0.1 0.57 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ETS87315.1 - 0.18 11.4 2.0 0.8 9.3 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain WD40 PF00400.32 ETS87316.1 - 1.7e-08 34.9 8.1 0.26 12.2 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ATP-synt_E PF05680.12 ETS87317.1 - 5e-21 74.8 0.2 5.4e-21 74.7 0.2 1.0 1 0 0 1 1 1 1 ATP synthase E chain ANAPC4_WD40 PF12894.7 ETS87318.1 - 0.00016 21.9 0.0 0.00078 19.7 0.0 2.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain SDA1 PF05285.12 ETS87318.1 - 0.00092 18.7 4.9 0.0022 17.5 4.9 1.5 1 0 0 1 1 1 1 SDA1 Nucleoporin_FG PF13634.6 ETS87318.1 - 0.0011 19.8 7.8 0.0011 19.8 7.8 7.3 5 1 2 7 7 7 2 Nucleoporin FG repeat region CDC45 PF02724.14 ETS87318.1 - 0.11 10.8 4.4 0.15 10.3 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein AAA_13 PF13166.6 ETS87318.1 - 0.48 9.0 3.4 0.68 8.5 3.4 1.2 1 0 0 1 1 1 0 AAA domain Na_trans_assoc PF06512.13 ETS87318.1 - 1.2 9.4 6.7 3.9 7.7 6.7 1.9 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 ETS87318.1 - 1.4 7.0 13.3 2.6 6.2 13.3 1.3 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 ETS87318.1 - 2.3 7.7 9.7 0.43 10.1 4.6 2.3 2 0 0 2 2 2 0 PPP4R2 KxDL PF10241.9 ETS87318.1 - 2.5 8.4 5.0 9.5 6.6 2.3 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein NOA36 PF06524.12 ETS87318.1 - 4.4 6.6 13.5 7.2 5.8 13.5 1.2 1 0 0 1 1 1 0 NOA36 protein Proteasome PF00227.26 ETS87319.1 - 3.3e-44 150.7 0.1 4.3e-44 150.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 ETS87319.1 - 1.3e-13 50.1 0.3 1.3e-13 50.1 0.3 1.9 3 0 0 3 3 3 1 Proteasome beta subunits C terminal Acetyltransf_3 PF13302.7 ETS87320.1 - 9.3e-27 94.4 0.0 1.1e-26 94.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ETS87320.1 - 3.7e-10 40.1 0.0 4.3e-10 39.9 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS87320.1 - 2.2e-09 37.6 0.0 2.7e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 ETS87320.1 - 0.0011 18.6 0.0 0.0014 18.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain COPIIcoated_ERV PF07970.12 ETS87321.1 - 1.5e-87 293.1 0.0 2.7e-87 292.2 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 ETS87321.1 - 5.2e-30 103.6 0.0 2.9e-29 101.3 0.0 2.2 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sel1 PF08238.12 ETS87322.1 - 4.6e-10 39.9 7.8 0.0078 16.9 0.1 3.9 4 0 0 4 4 4 3 Sel1 repeat CVNH PF08881.10 ETS87323.1 - 6.8e-12 46.0 6.9 7.4e-08 33.0 1.5 1.8 1 1 1 2 2 2 2 CVNH domain Pantoate_ligase PF02569.15 ETS87323.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Glyco_transf_17 PF04724.13 ETS87324.1 - 9.9e-55 186.0 2.1 5.6e-54 183.5 2.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 17 Nsp3_PL2pro PF12124.8 ETS87324.1 - 0.017 14.9 0.0 0.06 13.1 0.0 2.0 2 0 0 2 2 2 0 Coronavirus polyprotein cleavage domain Beta_elim_lyase PF01212.21 ETS87325.1 - 1.6e-70 237.7 0.0 2.2e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 ETS87325.1 - 0.0044 15.6 0.0 0.0083 14.7 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ETS87325.1 - 0.018 14.4 0.0 0.092 12.0 0.0 1.8 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Sec8_exocyst PF04048.14 ETS87325.1 - 0.14 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Ank_2 PF12796.7 ETS87326.1 - 7.2e-40 135.5 0.2 3.1e-12 46.9 0.0 8.9 9 1 0 9 9 9 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS87326.1 - 6.9e-32 109.4 0.3 2.9e-05 24.5 0.0 10.8 10 2 2 12 12 12 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 ETS87326.1 - 9e-29 96.3 0.4 0.0035 17.7 0.0 11.3 13 0 0 13 13 13 6 Ankyrin repeat Ank_5 PF13857.6 ETS87326.1 - 1.2e-28 98.8 1.5 0.012 16.0 0.1 10.5 9 1 1 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 ETS87326.1 - 5.2e-25 86.7 5.4 0.00012 22.4 0.0 10.9 11 0 0 11 11 11 4 Ankyrin repeat Polbeta PF18765.1 ETS87326.1 - 0.032 14.3 0.6 0.28 11.3 0.0 2.6 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase SAPS PF04499.15 ETS87326.1 - 3.6 6.3 8.8 1 8.1 2.6 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Trehalase PF01204.18 ETS87327.1 - 2.1e-112 376.6 10.1 2.1e-111 373.3 10.1 2.0 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 ETS87327.1 - 3.8e-05 22.8 0.6 9.8e-05 21.4 0.1 1.7 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase MMS19_N PF14500.6 ETS87328.1 - 8.1e-54 182.9 1.5 1.8e-53 181.8 0.4 2.2 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 ETS87328.1 - 2.3e-10 40.2 3.9 1.6e-08 34.1 0.0 3.5 3 2 0 4 4 4 2 RNAPII transcription regulator C-terminal Phasin_2 PF09361.10 ETS87328.1 - 0.053 13.8 0.6 2.4 8.5 0.0 3.9 5 0 0 5 5 5 0 Phasin protein Anti-adapt_IraP PF10796.9 ETS87328.1 - 0.058 14.0 0.2 30 5.3 0.1 3.1 3 0 0 3 3 3 0 Sigma-S stabilisation anti-adaptor protein C4 PF01413.19 ETS87328.1 - 0.065 13.6 0.1 0.19 12.1 0.1 1.8 1 0 0 1 1 1 0 C-terminal tandem repeated domain in type 4 procollagen THF_DHG_CYH PF00763.23 ETS87329.1 - 3e-27 95.2 0.1 4.6e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 ETS87329.1 - 1.5e-13 50.4 0.1 1.1e-08 34.6 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SPC25 PF06703.11 ETS87330.1 - 9e-54 181.6 0.7 1.1e-53 181.4 0.7 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Peptidase_U4 PF03419.13 ETS87330.1 - 0.096 12.0 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA EMC3_TMCO1 PF01956.16 ETS87331.1 - 7e-51 172.3 0.8 1e-50 171.8 0.8 1.3 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF2523 PF10734.9 ETS87331.1 - 0.21 12.2 0.2 0.21 12.2 0.2 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2523) DUF2208 PF09973.9 ETS87331.1 - 1.6 8.3 4.1 2.7 7.6 2.1 2.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2208) RNA_pol_Rbc25 PF08292.12 ETS87332.1 - 7.9e-32 110.2 2.3 2.7e-31 108.5 2.3 1.8 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 ETS87332.1 - 1.8e-14 53.8 0.0 2.9e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 ETS87332.1 - 0.025 14.9 0.0 0.051 13.9 0.0 1.5 1 1 0 1 1 1 0 S1 RNA binding domain NUFIP1 PF10453.9 ETS87333.1 - 1.3e-05 24.9 0.0 4.7e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 ETS87333.1 - 0.028 14.4 2.9 0.048 13.6 2.9 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ETS87333.1 - 0.12 12.4 5.9 0.24 11.5 5.9 1.5 1 0 0 1 1 1 0 Zinc finger domain Ribosomal_S8e PF01201.22 ETS87334.1 - 1.7e-44 151.3 2.3 3.5e-44 150.3 2.3 1.6 1 1 0 1 1 1 1 Ribosomal protein S8e Ribosomal_L21p PF00829.21 ETS87335.1 - 3.7e-12 46.4 0.0 4.8e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pkinase PF00069.25 ETS87336.1 - 4.8e-46 157.2 0.0 1.2e-45 155.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS87336.1 - 2.8e-19 69.4 0.0 5.6e-19 68.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ETS87336.1 - 0.0011 18.9 0.1 0.81 9.6 0.1 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Flagellin_D3 PF08884.11 ETS87336.1 - 0.046 14.1 1.4 0.11 12.9 1.4 1.6 1 0 0 1 1 1 0 Flagellin D3 domain Kinase-like PF14531.6 ETS87336.1 - 0.05 12.9 0.0 0.15 11.4 0.0 1.7 1 1 0 1 1 1 0 Kinase-like PsaA_PsaB PF00223.19 ETS87336.1 - 0.14 10.4 0.0 0.2 9.8 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Pkinase_fungal PF17667.1 ETS87336.1 - 1.5 7.5 3.4 4 6.1 0.0 2.4 2 0 0 2 2 2 0 Fungal protein kinase Ribosomal_60s PF00428.19 ETS87337.1 - 4.5e-27 94.5 12.5 5.2e-27 94.3 12.5 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein UBA_6 PF18039.1 ETS87337.1 - 0.053 13.4 1.0 0.073 13.0 0.1 1.6 2 0 0 2 2 2 0 UBA-like domain RibD_C PF01872.17 ETS87337.1 - 0.25 11.1 0.1 0.25 11.1 0.1 1.4 2 0 0 2 2 2 0 RibD C-terminal domain DUF3824 PF12868.7 ETS87337.1 - 0.32 11.7 2.6 0.44 11.2 2.6 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) SPT2 PF08243.11 ETS87338.1 - 3.1e-11 43.8 28.3 4.1e-10 40.2 28.3 2.2 1 1 0 1 1 1 1 SPT2 chromatin protein adh_short PF00106.25 ETS87339.1 - 1.4e-28 99.7 0.4 4.8e-22 78.4 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ETS87339.1 - 1.1e-19 70.9 0.1 2.9e-16 59.7 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS87339.1 - 1.1e-06 28.7 0.3 1.9e-06 27.9 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ETS87339.1 - 0.0011 18.9 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding PARP PF00644.20 ETS87340.1 - 4.6e-58 196.0 0.0 1.3e-57 194.6 0.0 1.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 ETS87340.1 - 1.3e-42 145.1 1.1 1.9e-42 144.6 1.1 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 ETS87340.1 - 2.3e-22 78.8 0.1 5e-22 77.7 0.1 1.6 1 0 0 1 1 1 1 WGR domain Transp_cyt_pur PF02133.15 ETS87341.1 - 2.3e-148 494.6 35.5 2.7e-148 494.4 35.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin F-box PF00646.33 ETS87342.1 - 0.0027 17.5 0.0 0.006 16.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain CH_2 PF06294.11 ETS87342.1 - 0.17 12.0 0.1 0.67 10.1 0.0 2.1 2 0 0 2 2 2 0 CH-like domain in sperm protein Abhydrolase_6 PF12697.7 ETS87343.1 - 6.3e-13 49.8 0.6 8.6e-13 49.4 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS87343.1 - 0.00012 21.4 0.1 0.0002 20.7 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS87343.1 - 0.0047 16.6 0.2 0.012 15.3 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Cys_Met_Meta_PP PF01053.20 ETS87344.1 - 2.1e-139 464.3 0.1 2.4e-139 464.1 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ETS87344.1 - 3.8e-08 32.9 0.2 5.7e-08 32.3 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ETS87344.1 - 7e-06 25.2 0.6 1.3e-05 24.4 0.4 1.5 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ETS87344.1 - 3.1e-05 23.5 2.2 6.3e-05 22.4 2.2 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 ETS87344.1 - 0.085 12.1 0.9 0.24 10.7 0.9 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase 2-Hacid_dh PF00389.30 ETS87344.1 - 0.09 12.4 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Terpene_synth_C PF03936.16 ETS87345.1 - 3.5e-10 39.7 0.0 6.7e-10 38.8 0.0 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain NR_Repeat PF14046.6 ETS87345.1 - 0.15 12.2 0.7 0.37 11.0 0.7 1.6 1 0 0 1 1 1 0 Nuclear receptor repeat F-box-like PF12937.7 ETS87346.1 - 1.6e-05 24.7 0.1 4.6e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS87346.1 - 0.029 14.3 0.1 0.073 13.0 0.1 1.7 1 0 0 1 1 1 0 F-box domain FAD_binding_3 PF01494.19 ETS87347.1 - 1e-15 57.8 0.1 7.7e-10 38.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Tubulin PF00091.25 ETS87348.1 - 3.2e-63 213.5 0.0 4.3e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ETS87348.1 - 6.7e-45 152.3 0.0 1e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 ETS87348.1 - 0.00012 21.8 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.22 ETS87349.1 - 1.8e-11 43.7 0.2 5.1e-08 32.6 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.11 ETS87350.1 - 2e-17 63.9 4.1 2e-17 63.9 4.1 2.2 2 1 0 2 2 2 1 Sds3-like DUF4524 PF15025.6 ETS87350.1 - 0.85 9.4 4.4 1.6 8.4 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) Coiled-coil_56 PF09813.9 ETS87351.1 - 0.0032 17.5 0.0 0.0034 17.4 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.8 ETS87352.1 - 7.3e-63 212.2 0.7 2e-62 210.8 0.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) DUF4680 PF15730.5 ETS87353.1 - 0.74 10.2 8.3 4.8 7.5 8.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4680) WH2 PF02205.20 ETS87355.1 - 7.9e-10 38.3 1.7 7.9e-10 38.3 1.7 3.4 4 0 0 4 4 4 1 WH2 motif Virul_fac_BrkB PF03631.15 ETS87357.1 - 0.012 15.2 4.8 0.018 14.6 4.8 1.2 1 0 0 1 1 1 0 Virulence factor BrkB DUF1282 PF06930.12 ETS87357.1 - 0.014 15.2 4.7 0.019 14.7 4.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) AgrB PF04647.15 ETS87357.1 - 0.021 14.2 0.5 0.03 13.6 0.5 1.2 1 0 0 1 1 1 0 Accessory gene regulator B SpoVAC_SpoVAEB PF03862.13 ETS87357.1 - 0.039 14.2 2.9 2.7 8.3 0.6 2.5 2 1 0 2 2 2 0 SpoVAC/SpoVAEB sporulation membrane protein Per1 PF04080.13 ETS87357.1 - 0.088 12.6 2.6 0.13 12.0 2.6 1.3 1 0 0 1 1 1 0 Per1-like family DUF2070 PF09843.9 ETS87357.1 - 0.13 10.6 1.8 0.16 10.2 1.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CHORD PF04968.12 ETS87358.1 - 6.3e-49 164.5 19.6 9.9e-25 87.0 7.0 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 ETS87358.1 - 2.4e-11 44.5 0.1 3.7e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 CS domain DUF836 PF05768.14 ETS87359.1 - 1.6e-14 54.0 0.0 2e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 ETS87359.1 - 7.2e-06 26.1 0.3 4.3e-05 23.6 0.0 2.2 2 1 0 2 2 2 1 Glutaredoxin HpcH_HpaI PF03328.14 ETS87360.1 - 3.9e-37 127.5 0.0 5e-37 127.2 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.6 ETS87360.1 - 0.0078 15.7 0.4 1.8 7.9 0.0 3.0 3 0 0 3 3 3 2 Phosphoenolpyruvate phosphomutase DUF2156 PF09924.9 ETS87360.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) Sugar_tr PF00083.24 ETS87361.1 - 3.1e-80 270.3 22.2 3.8e-80 270.0 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS87361.1 - 5.3e-32 111.1 38.5 7.5e-23 81.0 16.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ETS87361.1 - 9.8e-05 20.8 11.7 0.0033 15.8 3.4 3.1 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.18 ETS87362.1 - 2.6e-08 33.8 8.7 4.1e-08 33.2 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ETS87362.1 - 1.3e-06 27.5 0.1 2.4e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MOSC PF03473.17 ETS87363.1 - 5.1e-35 120.4 0.0 8.9e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 ETS87363.1 - 2.8e-23 82.5 0.0 9.8e-23 80.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 ETS87363.1 - 4.5e-21 74.9 0.0 8.3e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain AAA_16 PF13191.6 ETS87364.1 - 1.3e-11 45.2 0.0 4.4e-11 43.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ETS87364.1 - 6.9e-11 42.7 0.0 1.8e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ETS87364.1 - 1.8e-10 41.2 0.1 5.6e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain Cdc6_C PF09079.11 ETS87364.1 - 4e-08 33.1 0.4 8.4e-07 28.9 0.4 2.8 1 1 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 ETS87364.1 - 2.6e-06 27.5 0.0 6.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 AAA lid domain TniB PF05621.11 ETS87364.1 - 1e-05 25.0 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_19 PF13245.6 ETS87364.1 - 0.00034 21.0 0.4 0.0031 17.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ETS87364.1 - 0.00042 20.1 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ETS87364.1 - 0.0011 18.5 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 ETS87364.1 - 0.0026 17.7 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 ETS87364.1 - 0.0038 16.5 0.1 0.0073 15.6 0.1 1.5 1 1 0 1 1 1 1 KAP family P-loop domain AAA_14 PF13173.6 ETS87364.1 - 0.0051 16.8 0.0 0.016 15.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 ETS87364.1 - 0.0056 17.1 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase PPR_1 PF12854.7 ETS87364.1 - 0.0066 16.1 0.0 0.041 13.6 0.0 2.2 2 0 0 2 2 2 1 PPR repeat MMR_HSR1 PF01926.23 ETS87364.1 - 0.0083 16.2 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SseB_C PF14581.6 ETS87364.1 - 0.011 15.8 0.0 0.057 13.5 0.0 2.2 2 0 0 2 2 2 0 SseB protein C-terminal domain AAA_32 PF13654.6 ETS87364.1 - 0.033 13.0 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ETS87364.1 - 0.056 14.0 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ETS87364.1 - 0.058 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ETS87364.1 - 0.064 13.5 0.0 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ETS87364.1 - 0.065 13.2 0.0 0.19 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 ETS87364.1 - 0.13 11.4 0.0 0.26 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AFG1_ATPase PF03969.16 ETS87364.1 - 0.14 11.0 0.0 0.27 10.1 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase ATPase_2 PF01637.18 ETS87364.1 - 0.15 12.0 0.1 0.53 10.2 0.1 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Helicase_RecD PF05127.14 ETS87364.1 - 0.16 11.8 0.9 0.94 9.3 0.0 2.4 3 0 0 3 3 2 0 Helicase Arrestin_N PF00339.29 ETS87365.1 - 1.3e-14 54.5 0.0 1.4e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ETS87365.1 - 5.1e-08 33.5 0.0 0.00019 21.9 0.0 3.2 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.15 ETS87365.1 - 0.072 12.1 0.0 0.17 10.9 0.0 1.5 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 Ribosomal_L2_C PF03947.18 ETS87366.1 - 1.3e-50 170.8 2.3 1.3e-50 170.8 2.3 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ETS87366.1 - 6.3e-25 86.9 0.4 1.5e-24 85.7 0.4 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.23 ETS87367.1 - 2.8e-45 153.2 0.1 8.4e-45 151.6 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ETS87367.1 - 2e-33 115.0 0.3 4.4e-33 113.9 0.1 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain Ion_trans PF00520.31 ETS87371.1 - 1.1e-121 404.7 96.5 3.5e-41 141.1 10.9 4.8 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 ETS87371.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated JSRP PF15312.6 ETS87371.1 - 0.12 12.3 0.1 0.45 10.5 0.1 2.1 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein DUF2149 PF09919.9 ETS87371.1 - 2.3 8.5 9.0 2.2 8.6 0.2 4.8 5 0 0 5 5 5 0 Uncharacterized conserved protein (DUF2149) PHD PF00628.29 ETS87372.1 - 5.6e-08 32.6 9.1 1e-07 31.7 9.1 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ETS87372.1 - 0.0008 18.9 5.5 0.0015 18.1 5.5 1.4 1 0 0 1 1 1 1 PHD-finger HMG_box PF00505.19 ETS87373.1 - 9.5e-11 42.0 0.6 2e-10 40.9 0.6 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ETS87373.1 - 0.00074 20.1 0.4 0.0018 18.8 0.4 1.7 1 0 0 1 1 1 1 HMG-box domain Sec20 PF03908.13 ETS87374.1 - 8.6e-13 48.0 0.1 8.6e-13 48.0 0.1 2.4 4 0 0 4 4 4 1 Sec20 ALMT PF11744.8 ETS87374.1 - 0.5 9.1 3.5 0.65 8.8 3.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter MRP_L53 PF10780.9 ETS87375.1 - 8.9e-18 64.2 0.2 1.2e-17 63.8 0.2 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Pyrophosphatase PF00719.19 ETS87376.1 - 1.7e-59 200.2 0.1 2.3e-59 199.8 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.17 ETS87377.1 - 1.5e-43 149.1 0.4 6.4e-43 147.0 0.4 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Plus-3 PF03126.18 ETS87377.1 - 0.011 16.2 0.1 0.024 15.2 0.1 1.5 1 0 0 1 1 1 0 Plus-3 domain PucR PF07905.11 ETS87377.1 - 0.17 12.1 0.0 0.44 10.8 0.0 1.7 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Abhydrolase_6 PF12697.7 ETS87378.1 - 4.1e-21 76.6 1.8 4.1e-21 76.6 1.8 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS87378.1 - 3.3e-07 30.2 0.1 2.8e-06 27.2 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS87378.1 - 1.3e-06 27.9 0.0 2.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 ETS87378.1 - 0.0038 17.4 0.2 0.031 14.4 0.2 2.0 1 1 0 1 1 1 1 Thioesterase domain SLD5_C PF16922.5 ETS87379.1 - 5e-11 42.6 0.0 9e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 ETS87379.1 - 7.5e-06 26.4 0.5 1.7e-05 25.3 0.3 1.7 2 0 0 2 2 2 1 GINS complex protein TRPM_tetra PF16519.5 ETS87379.1 - 0.12 12.5 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 Tetramerisation domain of TRPM RPW8 PF05659.11 ETS87379.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 FMN_dh PF01070.18 ETS87380.1 - 3.7e-113 378.1 0.0 4.3e-113 377.9 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ETS87380.1 - 0.00011 21.5 0.1 0.00022 20.5 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 ETS87380.1 - 0.00017 21.0 0.4 0.29 10.4 0.0 3.0 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 ETS87380.1 - 0.00068 18.7 0.1 0.013 14.6 0.1 2.3 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 ETS87380.1 - 0.0087 15.5 1.4 0.014 14.8 1.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 ETS87380.1 - 0.034 13.6 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF2071 PF09844.9 ETS87380.1 - 0.084 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (COG2071) IGPS PF00218.21 ETS87380.1 - 0.14 11.3 0.0 0.65 9.1 0.0 1.9 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Fungal_trans_2 PF11951.8 ETS87381.1 - 6.9e-55 186.4 0.0 9.9e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fe-ADH PF00465.19 ETS87381.1 - 0.15 10.8 0.4 0.38 9.5 0.2 1.7 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase Pro_isomerase PF00160.21 ETS87382.1 - 3.9e-50 170.2 0.8 7.5e-50 169.3 0.1 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 ETS87382.1 - 3.2e-09 37.3 0.1 0.0001 23.0 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS87382.1 - 0.013 15.8 0.0 0.11 12.8 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS87382.1 - 0.018 14.0 0.5 0.25 10.3 0.1 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FAM199X PF15814.5 ETS87383.1 - 0.24 10.4 7.1 0.29 10.1 7.1 1.0 1 0 0 1 1 1 0 Protein family FAM199X DUF4407 PF14362.6 ETS87383.1 - 1 8.6 9.0 1.2 8.4 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LPP20 PF02169.16 ETS87383.1 - 2.4 8.5 8.1 3.6 8.0 8.1 1.3 1 0 0 1 1 1 0 LPP20 lipoprotein DEAD PF00270.29 ETS87384.1 - 5.3e-50 169.6 0.0 5.4e-49 166.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS87384.1 - 3.7e-27 94.9 0.0 1.3e-26 93.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS87384.1 - 0.0087 16.1 0.0 0.032 14.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ETS87384.1 - 0.78 9.0 0.0 0.78 9.0 0.0 3.9 5 0 0 5 5 5 0 U3-containing 90S pre-ribosomal complex subunit HMG_box_2 PF09011.10 ETS87385.1 - 3.4e-10 40.4 3.8 2e-07 31.5 0.6 2.8 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 ETS87385.1 - 3e-05 24.4 0.6 3e-05 24.4 0.6 3.3 3 1 0 3 3 3 2 HMG (high mobility group) box Pro-NT_NN PF07421.11 ETS87385.1 - 0.021 15.1 1.2 0.021 15.1 1.2 1.5 1 1 0 1 1 1 0 Neurotensin/neuromedin N precursor Methyltransf_11 PF08241.12 ETS87387.1 - 1.4e-12 48.1 0.0 3.5e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS87387.1 - 1.1e-05 26.0 0.0 2.9e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS87387.1 - 0.0087 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS87387.1 - 0.012 16.4 0.0 0.029 15.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain baeRF_family12 PF18856.1 ETS87388.1 - 5.3 7.6 7.2 12 6.5 7.2 1.6 1 1 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 EF1_GNE PF00736.19 ETS87390.1 - 1.1e-32 112.1 1.7 1.8e-32 111.4 1.7 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 ETS87390.1 - 3.1e-10 40.3 10.5 3.1e-10 40.3 10.5 2.5 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region DUF211 PF02680.14 ETS87390.1 - 0.12 12.5 0.5 0.19 11.9 0.5 1.4 1 1 0 1 1 1 0 Uncharacterized ArCR, COG1888 PRT_C PF08372.10 ETS87390.1 - 0.16 11.7 0.8 14 5.4 0.2 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal FMN_dh PF01070.18 ETS87391.1 - 1.3e-128 429.0 0.1 1.4e-128 428.8 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ETS87391.1 - 2.3e-09 36.7 0.0 4.7e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 ETS87391.1 - 2.1e-06 27.4 2.6 3.5e-06 26.6 0.8 2.1 2 1 0 2 2 2 1 Nitronate monooxygenase ThiG PF05690.14 ETS87391.1 - 3.7e-05 23.2 0.3 0.0019 17.6 0.1 2.7 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 ETS87391.1 - 5.7e-05 22.7 0.1 0.018 14.5 0.0 2.5 1 1 1 2 2 2 2 Histidine biosynthesis protein Glu_synthase PF01645.17 ETS87391.1 - 8.6e-05 21.8 0.1 0.00014 21.2 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 ETS87391.1 - 0.00039 19.7 0.1 0.0012 18.1 0.0 1.8 1 1 0 2 2 2 1 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 ETS87391.1 - 0.025 14.0 0.0 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator AAA_2 PF07724.14 ETS87392.1 - 9.3e-45 152.8 0.0 5e-44 150.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ETS87392.1 - 6.3e-36 122.4 2.7 6.3e-36 122.4 2.7 2.9 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 ETS87392.1 - 5.7e-25 87.2 1.8 7e-25 86.9 0.2 2.1 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 ETS87392.1 - 2.3e-19 70.1 0.0 3.1e-10 40.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ETS87392.1 - 1.7e-12 47.5 0.0 1.2e-08 35.1 0.0 3.2 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ETS87392.1 - 2.3e-09 37.8 7.6 0.0007 20.0 0.1 4.3 3 2 0 4 4 3 2 AAA ATPase domain Sigma54_activat PF00158.26 ETS87392.1 - 2.1e-07 30.8 0.1 9.8e-05 22.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 ETS87392.1 - 3.4e-07 30.6 4.4 0.017 15.4 0.0 3.7 3 2 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 ETS87392.1 - 3.2e-06 27.2 4.8 0.21 11.5 0.0 4.1 3 2 1 5 5 4 2 ATPase domain predominantly from Archaea NACHT PF05729.12 ETS87392.1 - 1.4e-05 25.1 0.0 0.27 11.2 0.0 2.7 2 0 0 2 2 2 2 NACHT domain TniB PF05621.11 ETS87392.1 - 1.6e-05 24.4 0.0 0.0064 15.9 0.0 3.5 3 1 0 3 3 2 1 Bacterial TniB protein AAA_14 PF13173.6 ETS87392.1 - 2.8e-05 24.1 0.0 0.44 10.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 ETS87392.1 - 4.9e-05 22.9 0.0 0.2 11.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 ETS87392.1 - 0.00022 21.0 0.1 0.73 9.5 0.0 2.8 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 ETS87392.1 - 0.00065 20.3 0.8 0.12 13.0 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 ETS87392.1 - 0.0015 18.3 0.0 0.25 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ETS87392.1 - 0.0024 18.2 0.0 0.36 11.3 0.0 2.9 2 1 0 2 2 2 1 RNA helicase SRP54 PF00448.22 ETS87392.1 - 0.0024 17.5 0.0 0.11 12.1 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 ETS87392.1 - 0.0026 17.5 0.1 0.51 10.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 ETS87392.1 - 0.0061 16.8 1.0 9.5 6.4 0.0 3.7 3 1 0 3 3 3 0 AAA domain Roc PF08477.13 ETS87392.1 - 0.0062 16.7 0.1 0.81 9.9 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 ETS87392.1 - 0.0068 16.3 0.0 1.5 8.7 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase ResIII PF04851.15 ETS87392.1 - 0.0074 16.3 1.2 5.1 7.1 0.0 3.7 3 1 0 4 4 3 0 Type III restriction enzyme, res subunit TsaE PF02367.17 ETS87392.1 - 0.008 16.2 0.1 3.5 7.6 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 ETS87392.1 - 0.011 16.3 1.6 1 9.8 0.0 3.3 3 0 0 3 3 3 0 ABC transporter Mg_chelatase PF01078.21 ETS87392.1 - 0.012 15.0 0.0 4.1 6.7 0.0 3.1 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI ERM PF00769.19 ETS87392.1 - 0.015 15.1 10.9 0.025 14.4 10.9 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AAA_33 PF13671.6 ETS87392.1 - 0.017 15.3 0.0 8.3 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 ETS87392.1 - 0.017 14.3 0.3 1 8.4 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 ETS87392.1 - 0.034 13.4 0.0 0.95 8.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin UvrD-helicase PF00580.21 ETS87392.1 - 0.039 13.5 3.9 0.43 10.0 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain PhoH PF02562.16 ETS87392.1 - 0.04 13.4 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein PIF1 PF05970.14 ETS87392.1 - 0.046 12.9 0.0 1.2 8.2 0.0 2.6 3 0 0 3 3 3 0 PIF1-like helicase PduV-EutP PF10662.9 ETS87392.1 - 0.047 13.4 0.0 0.81 9.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 ETS87392.1 - 0.056 13.0 0.0 0.84 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ETS87392.1 - 0.081 12.8 0.1 0.55 10.1 0.0 2.4 2 0 0 2 2 2 0 NTPase DUF4407 PF14362.6 ETS87392.1 - 0.09 12.1 4.5 0.14 11.5 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_19 PF13245.6 ETS87392.1 - 0.18 12.2 4.7 0.83 10.0 0.0 3.5 4 1 0 4 4 2 0 AAA domain AAA_6 PF12774.7 ETS87392.1 - 0.18 10.7 0.0 1.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region CENP-F_leu_zip PF10473.9 ETS87392.1 - 0.24 11.4 17.2 3.3 7.7 17.2 2.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_23 PF13476.6 ETS87392.1 - 0.52 10.8 18.8 31 5.0 18.8 3.0 2 1 0 2 2 2 0 AAA domain OEP PF02321.18 ETS87392.1 - 0.83 9.4 12.0 1.8 8.3 12.0 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein Macoilin PF09726.9 ETS87392.1 - 0.91 8.0 4.9 1.4 7.4 4.9 1.2 1 0 0 1 1 1 0 Macoilin family HAUS2 PF15003.6 ETS87392.1 - 1.7 8.4 9.8 1.7 8.3 4.0 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 2 DUF4349 PF14257.6 ETS87392.1 - 1.7 8.1 15.1 2.4 7.6 5.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) UPF0242 PF06785.11 ETS87392.1 - 4.5 7.3 12.2 12 5.9 12.2 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 ETS87392.1 - 6.3 6.6 14.1 6.2 6.7 7.5 2.7 1 1 1 2 2 2 0 Septum formation initiator DUF2968 PF11180.8 ETS87392.1 - 9.9 5.7 11.5 24 4.5 11.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) ATP11 PF06644.11 ETS87393.1 - 1.6e-87 293.8 0.0 1.9e-87 293.5 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein AMP-binding PF00501.28 ETS87394.1 - 4.2e-94 315.5 0.0 5.3e-94 315.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ETS87394.1 - 2.6e-13 50.8 0.2 4.9e-13 49.9 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydro_lipase PF04083.16 ETS87395.1 - 2.2e-20 72.0 0.0 4.6e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 ETS87395.1 - 6.9e-05 22.6 0.1 0.00025 20.8 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS87395.1 - 0.0044 16.3 0.0 0.022 14.0 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AAA PF00004.29 ETS87396.1 - 4.3e-51 172.8 0.0 7.1e-43 146.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS87396.1 - 0.00012 22.5 4.9 0.022 15.1 0.0 4.7 3 2 0 4 4 4 1 AAA ATPase domain RuvB_N PF05496.12 ETS87396.1 - 0.00017 21.4 0.0 0.00057 19.7 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 ETS87396.1 - 0.0008 18.6 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 ETS87396.1 - 0.0014 19.0 0.0 0.04 14.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 ETS87396.1 - 0.0017 18.0 0.1 0.029 14.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 ETS87396.1 - 0.0036 17.5 0.0 0.0092 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 ETS87396.1 - 0.0064 16.8 0.0 0.037 14.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ETS87396.1 - 0.008 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 ETS87396.1 - 0.011 15.0 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_lid_3 PF17862.1 ETS87396.1 - 0.016 15.0 2.5 0.13 12.1 0.0 3.0 3 0 0 3 3 3 0 AAA+ lid domain Mg_chelatase PF01078.21 ETS87396.1 - 0.026 13.9 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 ETS87396.1 - 0.027 14.5 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 ETS87396.1 - 0.034 13.5 0.0 0.085 12.2 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 ETS87396.1 - 0.037 14.0 0.0 0.14 12.2 0.0 2.1 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 ETS87396.1 - 0.037 14.1 0.0 0.73 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ETS87396.1 - 0.051 13.1 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 ETS87396.1 - 0.058 13.9 0.0 0.17 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ETS87396.1 - 0.065 13.4 0.0 0.4 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 ETS87396.1 - 0.092 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 ETS87396.1 - 0.1 12.9 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 ETS87396.1 - 0.1 11.8 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 ETS87396.1 - 0.15 11.3 0.0 4 6.6 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.6 ETS87396.1 - 0.17 11.6 0.2 1.1 9.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain Abhydrolase_1 PF00561.20 ETS87398.1 - 3e-10 40.2 0.0 5.1e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS87398.1 - 9.4e-07 28.3 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ETS87398.1 - 9.3e-05 22.0 0.0 0.0018 17.8 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ETS87398.1 - 0.029 14.0 0.0 0.082 12.5 0.0 1.7 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) CwfJ_C_1 PF04677.15 ETS87400.1 - 4.8e-26 91.0 0.0 8.1e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 ETS87400.1 - 1.3e-13 51.7 0.3 2.9e-13 50.5 0.3 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DRIM PF07539.12 ETS87401.1 - 9.5e-193 641.9 0.1 1.7e-191 637.7 0.0 3.1 3 0 0 3 3 3 1 Down-regulated in metastasis HEAT_2 PF13646.6 ETS87401.1 - 2.2e-06 27.9 9.7 2.2 8.7 0.1 8.6 9 0 0 9 9 9 2 HEAT repeats HEAT PF02985.22 ETS87401.1 - 0.00019 21.4 11.4 3.7 8.1 0.0 8.6 9 0 0 9 9 9 2 HEAT repeat Arm PF00514.23 ETS87401.1 - 0.0036 17.3 1.1 29 4.9 0.0 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 ETS87401.1 - 0.085 13.4 7.6 40 4.9 0.0 7.2 8 0 0 8 8 8 0 HEAT-like repeat Npa1 PF11707.8 ETS87401.1 - 0.087 12.2 0.3 0.77 9.1 0.1 2.7 3 0 0 3 3 3 0 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 ETS87401.1 - 0.099 12.2 2.0 14 5.2 0.2 4.5 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 UNC45-central PF11701.8 ETS87401.1 - 0.25 11.3 3.7 2.6 8.0 0.1 4.4 6 0 0 6 6 6 0 Myosin-binding striated muscle assembly central Sec7_N PF12783.7 ETS87401.1 - 9.3 6.1 12.0 38 4.1 0.1 6.1 6 1 1 7 7 7 0 Guanine nucleotide exchange factor in Golgi transport N-terminal zf-DNL PF05180.12 ETS87402.1 - 2.1e-27 94.8 0.2 3.3e-27 94.2 0.2 1.3 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.13 ETS87402.1 - 0.0076 15.9 0.3 0.017 14.8 0.3 1.5 1 0 0 1 1 1 1 CSL zinc finger Elf1 PF05129.13 ETS87402.1 - 0.13 12.3 0.2 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like PepSY PF03413.19 ETS87402.1 - 0.16 12.6 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Cullin PF00888.22 ETS87403.1 - 1.6e-182 608.4 1.3 2.4e-182 607.8 1.3 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ETS87403.1 - 6.1e-24 83.8 3.1 1.6e-23 82.5 3.1 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF724 PF05266.14 ETS87403.1 - 0.14 12.0 0.1 0.14 12.0 0.1 2.9 3 1 0 4 4 4 0 Protein of unknown function (DUF724) SR-25 PF10500.9 ETS87404.1 - 0.0082 15.8 21.6 0.019 14.6 21.6 1.6 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein MAP65_ASE1 PF03999.12 ETS87404.1 - 1.4 7.5 4.3 1.5 7.5 4.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Pox_A12 PF04651.13 ETS87404.1 - 2.2 8.3 6.8 3.9 7.5 6.8 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein DUF508 PF04370.12 ETS87404.1 - 2.3 8.0 8.4 3.9 7.2 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) CCDC106 PF15794.5 ETS87404.1 - 2.3 7.9 6.8 4.7 6.9 6.8 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 GH131_N PF18271.1 ETS87405.1 - 8.8e-82 274.6 2.0 9.9e-82 274.5 2.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain FluMu_N PF17891.1 ETS87405.1 - 0.0026 17.5 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 Mu-like prophage FluMu N-terminal domain GW PF13457.6 ETS87405.1 - 0.13 12.8 1.5 0.22 12.2 0.4 2.1 2 0 0 2 2 2 0 GW (Gly-Tryp) dipeptide domain Polysacc_deac_1 PF01522.21 ETS87407.1 - 2.5e-13 50.0 0.0 4.7e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 ETS87407.1 - 0.06 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DPPIV_N PF00930.21 ETS87408.1 - 1.3e-108 363.0 0.4 1.6e-108 362.6 0.4 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 ETS87408.1 - 1.3e-54 184.9 2.3 2.3e-54 184.1 2.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ETS87408.1 - 0.00019 21.1 7.5 0.00045 19.9 2.1 2.7 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 ETS87408.1 - 0.0082 16.8 0.7 0.073 13.7 0.2 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Methyltranf_PUA PF13636.6 ETS87408.1 - 0.058 13.4 0.1 14 5.8 0.1 2.7 2 0 0 2 2 2 0 RNA-binding PUA-like domain of methyltransferase RsmF ICMT PF04140.14 ETS87409.1 - 3.2e-10 40.3 0.3 2.3e-08 34.4 0.2 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 ETS87409.1 - 4.3e-06 27.1 0.3 0.00014 22.2 0.1 2.4 1 1 2 3 3 3 1 Phospholipid methyltransferase NnrU PF07298.11 ETS87409.1 - 0.0023 17.5 2.7 0.16 11.4 0.2 2.9 2 1 1 3 3 3 2 NnrU protein Cu-oxidase_2 PF07731.14 ETS87410.1 - 2.9e-43 146.9 10.5 1.4e-41 141.5 1.3 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ETS87410.1 - 2.5e-39 134.0 6.3 7.7e-39 132.4 2.5 3.1 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 ETS87410.1 - 1.8e-37 128.9 0.2 1.8e-37 128.9 0.2 2.2 2 1 1 3 3 3 1 Multicopper oxidase Wzt_C PF14524.6 ETS87410.1 - 0.0018 18.3 0.1 0.0045 17.0 0.1 1.6 1 0 0 1 1 1 1 Wzt C-terminal domain Big_11 PF18200.1 ETS87410.1 - 0.02 14.8 0.1 0.06 13.3 0.1 1.8 1 0 0 1 1 1 0 Bacterial Ig-like domain Pkinase PF00069.25 ETS87414.1 - 7.9e-08 32.0 0.0 0.0055 16.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS87414.1 - 4.2e-05 23.0 0.0 0.025 13.9 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 ETS87414.1 - 0.005 16.8 0.1 0.04 13.8 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Ig_GlcNase PF18368.1 ETS87415.1 - 7.9e-34 116.0 4.0 1.8e-33 114.8 0.6 2.5 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 ETS87415.1 - 1.9e-10 41.4 0.0 6.4e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 ETS87415.1 - 0.00042 20.9 2.3 0.00073 20.1 0.5 2.5 2 1 0 2 2 2 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 ETS87415.1 - 0.0022 17.7 0.9 0.0055 16.4 0.1 2.1 2 0 0 2 2 2 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 ETS87415.1 - 0.0051 16.0 0.1 0.0077 15.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Saf-Nte_pilin PF09460.10 ETS87415.1 - 0.039 14.0 0.5 0.45 10.5 0.1 2.3 2 0 0 2 2 2 0 Saf-pilin pilus formation protein DnaJ PF00226.31 ETS87418.1 - 3.4e-10 39.9 0.6 8.2e-10 38.7 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain p450 PF00067.22 ETS87419.1 - 6.6e-72 242.7 0.0 8.4e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DnaJ PF00226.31 ETS87420.1 - 6.8e-20 71.0 2.3 1.2e-19 70.2 2.3 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 ETS87420.1 - 0.0014 18.9 0.3 0.0021 18.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Sororin PF09666.10 ETS87421.1 - 1.8 8.8 5.7 1.9 8.7 5.0 1.3 1 1 0 1 1 1 0 Sororin protein PRA1 PF03208.19 ETS87422.1 - 3e-32 111.2 2.0 3e-32 111.2 2.0 2.0 2 0 0 2 2 2 1 PRA1 family protein DNA_pol_phi PF04931.13 ETS87422.1 - 0.16 10.1 4.1 0.21 9.7 4.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Promethin PF16015.5 ETS87422.1 - 0.78 9.7 6.5 1.3 9.0 6.5 1.3 1 0 0 1 1 1 0 Promethin CMAS PF02353.20 ETS87423.1 - 2.2e-14 53.4 0.0 3.2e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 ETS87423.1 - 1.7e-13 50.8 0.0 2.5e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS87423.1 - 6.4e-09 36.4 0.0 2.2e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS87423.1 - 8.6e-08 32.7 0.0 2.7e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS87423.1 - 1.2e-05 25.9 0.0 4.7e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS87423.1 - 8.3e-05 22.4 0.0 0.00089 19.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ETS87423.1 - 0.0022 17.6 0.0 0.023 14.3 0.0 2.3 3 0 0 3 3 3 1 Methionine biosynthesis protein MetW MTS PF05175.14 ETS87423.1 - 0.045 13.3 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 ETS87423.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PITH PF06201.13 ETS87424.1 - 2.7e-40 138.0 0.1 4.1e-40 137.5 0.1 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 ETS87424.1 - 2e-24 85.5 0.0 3.5e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ETS87424.1 - 5.9e-07 29.9 0.0 1.4e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ETS87424.1 - 6.1e-05 23.3 0.0 0.035 14.4 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 ETS87424.1 - 0.0062 16.3 0.0 0.0095 15.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 ETS87424.1 - 0.011 15.6 0.1 0.083 12.8 0.1 2.1 1 1 0 1 1 1 0 AhpC/TSA family OST3_OST6 PF04756.13 ETS87424.1 - 0.082 12.2 0.0 0.2 10.9 0.0 1.5 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Redoxin PF08534.10 ETS87424.1 - 0.084 12.6 0.1 0.41 10.4 0.1 2.0 1 1 1 2 2 2 0 Redoxin Glyco_hydro_61 PF03443.14 ETS87426.1 - 1.1e-63 214.9 1.0 2e-63 214.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 ETS87426.1 - 3.4e-08 33.3 10.0 9.7e-08 31.8 10.0 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF572 PF04502.13 ETS87426.1 - 4.2 6.9 8.0 5.6 6.5 8.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Apt1 PF10351.9 ETS87426.1 - 8.9 5.0 18.8 12 4.6 18.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peptidase_M14 PF00246.24 ETS87427.1 - 5.5e-73 246.3 0.0 6.8e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 ETS87427.1 - 0.0093 16.3 0.2 0.035 14.5 0.1 2.1 2 0 0 2 2 2 1 Carboxypeptidase activation peptide adh_short_C2 PF13561.6 ETS87428.1 - 4.7e-41 140.9 0.1 1.1e-40 139.7 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS87428.1 - 4.7e-35 120.8 0.1 6.9e-35 120.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS87428.1 - 1.2e-08 35.0 0.7 2.4e-08 34.1 0.7 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS87428.1 - 0.032 13.7 0.4 0.078 12.4 0.2 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ETS87428.1 - 0.036 14.3 0.3 0.062 13.6 0.3 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ADH_N PF08240.12 ETS87429.1 - 7.4e-24 83.7 1.0 1.2e-23 83.0 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS87429.1 - 2.6e-23 82.4 0.1 4.7e-23 81.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS87429.1 - 0.00026 22.1 0.0 0.00073 20.6 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ETS87429.1 - 0.00076 18.9 0.1 0.0017 17.7 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ETS87429.1 - 0.004 16.5 0.2 0.0073 15.6 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 ETS87429.1 - 0.011 16.5 0.1 0.03 15.0 0.1 1.8 2 0 0 2 2 2 0 Methyltransferase domain 3HCDH_N PF02737.18 ETS87429.1 - 0.014 15.2 0.3 0.014 15.2 0.3 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain BKACE PF05853.12 ETS87429.1 - 0.024 13.9 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme Methyltransf_31 PF13847.6 ETS87429.1 - 0.072 12.9 0.1 0.17 11.7 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain PglD_N PF17836.1 ETS87429.1 - 0.11 13.1 0.3 0.26 12.0 0.3 1.7 1 0 0 1 1 1 0 PglD N-terminal domain TrkA_N PF02254.18 ETS87429.1 - 0.13 12.6 0.3 0.22 11.8 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain ADH_N_2 PF16884.5 ETS87429.1 - 0.14 12.0 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Glyco_hydro_3 PF00933.21 ETS87430.1 - 2.7e-52 178.1 0.0 4.7e-52 177.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 ETS87430.1 - 7.1e-51 173.1 0.0 1.2e-50 172.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 ETS87430.1 - 3.7e-11 43.0 0.0 7.7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 ETS87430.1 - 3.4e-07 30.2 0.0 8.7e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 PA14 domain Zn_clus PF00172.18 ETS87431.1 - 4e-05 23.6 12.2 6.9e-05 22.9 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS87431.1 - 0.00027 20.0 0.0 0.00069 18.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain KI67R PF08065.12 ETS87431.1 - 0.087 13.4 5.2 0.25 11.9 5.2 1.7 1 0 0 1 1 1 0 KI67R (NUC007) repeat Abhydrolase_1 PF00561.20 ETS87433.1 - 2e-12 47.3 0.0 5.4e-12 45.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS87433.1 - 3.3e-07 29.8 0.0 1.2e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS87433.1 - 6.9e-07 30.1 4.7 6.9e-07 30.1 4.7 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.11 ETS87433.1 - 0.029 14.3 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.10 ETS87433.1 - 0.039 14.1 0.0 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 TAP-like protein CBS PF00571.28 ETS87433.1 - 0.089 13.2 0.1 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 CBS domain NAS PF03059.16 ETS87434.1 - 1.8e-62 211.2 0.0 5.4e-62 209.6 0.0 1.6 1 1 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_31 PF13847.6 ETS87434.1 - 0.0005 19.9 0.0 0.00094 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF3147 PF11345.8 ETS87434.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3147) PPL5 PF18168.1 ETS87434.1 - 0.21 10.9 1.8 0.26 10.6 1.0 1.5 2 0 0 2 2 2 0 Prim-pol family 5 TFIIF_alpha PF05793.12 ETS87434.1 - 0.69 8.4 7.5 1 7.9 7.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NOA36 PF06524.12 ETS87434.1 - 3.2 7.0 9.3 5 6.3 9.3 1.2 1 0 0 1 1 1 0 NOA36 protein RhoGAP PF00620.27 ETS87435.1 - 4e-41 140.4 0.1 1.7e-40 138.3 0.1 2.0 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 ETS87435.1 - 3.8e-12 46.7 0.0 7e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 ETS87435.1 - 0.066 13.5 0.0 0.35 11.2 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain PX PF00787.24 ETS87435.1 - 0.081 12.9 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 PX domain TMEM52 PF14979.6 ETS87437.1 - 0.14 12.1 0.4 0.38 10.7 0.4 1.8 1 0 0 1 1 1 0 Transmembrane 52 EBP50_C PF09007.11 ETS87438.1 - 0.26 12.3 4.2 0.35 11.9 4.0 1.4 1 1 0 1 1 1 0 EBP50, C-terminal DUF3915 PF13054.6 ETS87438.1 - 0.31 11.0 1.8 0.7 9.9 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Adeno_E3_CR2 PF02439.15 ETS87440.1 - 0.00051 19.7 1.9 0.0009 18.9 1.9 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 TMEM51 PF15345.6 ETS87440.1 - 0.0014 18.5 0.1 0.0021 17.9 0.1 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 EphA2_TM PF14575.6 ETS87440.1 - 0.042 14.7 0.0 0.082 13.8 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 ETS87440.1 - 0.042 13.3 4.2 0.094 12.1 4.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TerD PF02342.18 ETS87440.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 TerD domain Shisa PF13908.6 ETS87440.1 - 0.16 12.2 0.1 0.16 12.2 0.1 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Gram_pos_anchor PF00746.21 ETS87440.1 - 0.16 11.9 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif RIFIN PF02009.16 ETS87440.1 - 0.17 11.8 0.3 0.17 11.8 0.3 1.4 2 0 0 2 2 2 0 Rifin CD34_antigen PF06365.12 ETS87440.1 - 0.27 10.8 0.1 0.46 10.0 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Stevor PF17410.2 ETS87440.1 - 0.62 9.5 1.7 0.98 8.9 1.7 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Miga PF10265.9 ETS87440.1 - 0.65 8.9 1.4 0.72 8.8 0.2 1.6 1 1 1 2 2 2 0 Mitoguardin DUF1593 PF07632.11 ETS87443.1 - 1.1e-80 270.8 0.0 1.5e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 ETS87443.1 - 0.00015 20.7 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 REJ domain Big_9 PF17963.1 ETS87443.1 - 0.00035 21.3 1.9 0.00038 21.1 0.1 1.9 2 0 0 2 2 2 1 Bacterial Ig domain Lactamase_B_2 PF12706.7 ETS87444.1 - 1.4e-14 54.1 2.6 3.9e-13 49.4 1.5 2.6 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ETS87444.1 - 4.6e-14 52.6 0.1 2.1e-10 40.7 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ETS87444.1 - 0.019 15.0 4.8 0.038 14.0 0.3 2.9 2 2 1 3 3 3 0 Metallo-beta-lactamase superfamily Abhydrolase_6 PF12697.7 ETS87446.1 - 3.4e-11 44.2 0.0 4.1e-11 43.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS87446.1 - 0.027 14.1 0.0 0.13 11.9 0.0 1.9 1 1 0 2 2 2 0 alpha/beta hydrolase fold Acetyltransf_7 PF13508.7 ETS87447.1 - 3.3e-10 40.2 0.1 5.6e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ETS87447.1 - 1.3e-08 34.9 0.1 2e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS87447.1 - 1.1e-07 32.1 0.0 6.2e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ETS87447.1 - 4.1e-05 23.7 0.0 0.0012 19.0 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain PD40 PF07676.12 ETS87448.1 - 6.1e-51 169.4 23.6 7.7e-10 38.5 1.6 9.7 9 0 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 ETS87448.1 - 9.4e-12 44.4 2.4 0.0059 15.4 0.0 6.5 4 2 2 6 6 6 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF5050 PF16472.5 ETS87448.1 - 2.7e-05 23.5 0.0 0.0084 15.4 0.0 4.0 4 1 0 4 4 4 1 Domain of unknown function (DUF5050) DUF3748 PF12566.8 ETS87448.1 - 0.0095 15.9 0.6 9.4 6.2 0.0 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF3748) GspH PF12019.8 ETS87448.1 - 0.033 14.6 0.8 0.033 14.6 0.8 3.6 2 2 1 3 3 3 0 Type II transport protein GspH WD40 PF00400.32 ETS87448.1 - 0.98 10.4 8.6 37 5.4 0.1 5.4 6 1 0 6 6 6 0 WD domain, G-beta repeat TM_helix PF05552.12 ETS87449.1 - 0.087 12.8 2.0 0.21 11.6 2.0 1.6 1 0 0 1 1 1 0 Conserved TM helix MFS_1 PF07690.16 ETS87450.1 - 9.5e-54 182.6 32.4 9.5e-54 182.6 32.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ETS87450.1 - 1.4e-08 34.5 9.2 1.4e-08 34.5 9.2 3.1 2 2 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 ETS87450.1 - 3.2e-08 32.9 19.8 3.2e-08 32.9 19.8 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 ETS87450.1 - 0.0008 17.8 5.6 0.0008 17.8 5.6 2.7 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 ETS87451.1 - 2.7e-50 171.5 0.2 3.9e-50 171.0 0.2 1.3 1 1 0 1 1 1 1 Cytochrome P450 HTH_56 PF18662.1 ETS87451.1 - 0.11 12.6 0.0 9.8 6.3 0.0 2.6 1 1 1 2 2 2 0 Cch helix turn helix domain Fungal_trans_2 PF11951.8 ETS87452.1 - 2.8e-07 29.7 1.1 4.7e-07 29.0 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tme5_EGF_like PF09064.10 ETS87453.1 - 0.0036 17.2 1.5 0.0096 15.8 1.5 1.7 1 0 0 1 1 1 1 Thrombomodulin like fifth domain, EGF-like MGC-24 PF05283.11 ETS87453.1 - 3.1 8.2 10.5 5.9 7.3 10.5 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glyco_hydro_127 PF07944.12 ETS87454.1 - 1.7e-25 89.5 0.0 2.6e-22 79.0 0.0 2.1 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_32C PF08244.12 ETS87455.1 - 1.7e-22 80.1 1.2 3e-22 79.3 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 ETS87455.1 - 3.3e-12 46.6 0.0 5.3e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain HET PF06985.11 ETS87456.1 - 4.7e-27 95.1 0.0 8.1e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Dimer_Tnp_hAT PF05699.14 ETS87457.1 - 9.5e-13 47.8 0.0 2.5e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 ETS87457.1 - 0.17 12.3 0.0 0.52 10.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) ShK PF01549.24 ETS87458.1 - 0.13 12.9 6.3 0.075 13.6 4.2 1.7 2 0 0 2 2 2 0 ShK domain-like DDE_1 PF03184.19 ETS87460.1 - 1.8e-20 73.3 0.0 1.1e-18 67.5 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease DUF603 PF04645.12 ETS87460.1 - 0.11 12.2 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF603 ABC2_membrane PF01061.24 ETS87461.1 - 1.5e-79 266.3 37.3 2e-42 145.0 10.4 2.2 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 ETS87461.1 - 2.5e-38 131.7 0.0 2e-18 67.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ETS87461.1 - 1.5e-19 69.7 0.1 4.3e-19 68.2 0.1 1.9 1 0 0 1 1 1 1 CDR ABC transporter ABC_trans_N PF14510.6 ETS87461.1 - 4.9e-08 33.5 0.1 1.3e-07 32.1 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 ETS87461.1 - 2.3e-06 27.0 26.3 0.00019 20.7 7.0 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 ETS87461.1 - 2.2e-05 24.4 0.1 0.0027 17.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 ETS87461.1 - 2.4e-05 24.9 0.0 0.33 11.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 ETS87461.1 - 3.1e-05 24.4 0.1 0.013 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 ETS87461.1 - 0.00012 21.7 0.6 0.017 14.9 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ETS87461.1 - 0.00019 21.1 0.4 0.0024 17.5 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 ETS87461.1 - 0.00039 20.3 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 ETS87461.1 - 0.0055 16.3 1.1 0.79 9.3 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 ETS87461.1 - 0.0065 16.7 0.5 0.9 9.8 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ETS87461.1 - 0.0068 16.7 0.1 1.1 9.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ETS87461.1 - 0.013 15.2 0.2 3 7.5 0.2 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ETS87461.1 - 0.018 15.1 0.2 7.1 6.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 ETS87461.1 - 0.023 14.1 0.0 2.3 7.6 0.0 2.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 ETS87461.1 - 0.033 14.3 0.0 0.69 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ETS87461.1 - 0.054 13.4 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 ETS87461.1 - 0.079 12.7 0.3 3.6 7.3 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 ETS87461.1 - 0.13 12.5 0.1 3.7 7.8 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Fungal_trans PF04082.18 ETS87462.1 - 9.3e-09 34.7 0.4 1.7e-08 33.8 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fe_dep_repr_C PF02742.15 ETS87462.1 - 0.18 11.9 0.1 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain Cep3 PF16846.5 ETS87463.1 - 0.13 10.7 1.9 0.31 9.5 1.9 1.6 1 1 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Zn_clus PF00172.18 ETS87463.1 - 6.5 7.0 22.4 0.031 14.4 12.3 2.4 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.15 ETS87464.1 - 2e-57 195.0 23.0 2.3e-57 194.7 23.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.6 ETS87465.1 - 1.2e-33 116.3 0.0 1.8e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS87465.1 - 6.8e-22 77.9 0.0 1e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily URO-D PF01208.17 ETS87465.1 - 0.14 11.3 0.0 0.38 9.8 0.0 1.6 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) Abhydrolase_1 PF00561.20 ETS87466.1 - 8.7e-22 78.0 0.0 3.1e-18 66.3 0.2 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS87466.1 - 1.8e-19 70.0 0.0 2.4e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS87466.1 - 1.8e-16 61.4 0.1 2.1e-16 61.2 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 ETS87466.1 - 1.7e-07 30.2 0.0 2.1e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 ETS87466.1 - 0.001 18.8 0.2 0.0018 18.0 0.2 1.4 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 ETS87466.1 - 0.001 18.8 0.7 0.0046 16.7 0.5 1.9 1 1 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.20 ETS87466.1 - 0.0031 17.7 0.0 0.0043 17.2 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain DUF900 PF05990.12 ETS87466.1 - 0.0096 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.25 ETS87466.1 - 0.014 15.2 0.1 0.022 14.6 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.11 ETS87466.1 - 0.025 13.9 0.1 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_8 PF06259.12 ETS87466.1 - 0.029 14.0 0.7 0.061 12.9 0.5 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase DUF676 PF05057.14 ETS87466.1 - 0.042 13.4 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 ETS87466.1 - 0.072 12.9 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 ETS87466.1 - 0.083 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pro_CA PF00484.19 ETS87466.1 - 0.085 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Carbonic anhydrase Peptidase_S9 PF00326.21 ETS87466.1 - 0.19 11.2 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Palm_thioest PF02089.15 ETS87466.1 - 0.21 11.4 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DIOX_N PF14226.6 ETS87467.1 - 1.7e-16 61.1 0.0 3.1e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS87467.1 - 2.5e-14 53.6 0.0 6.2e-14 52.3 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF3435 PF11917.8 ETS87468.1 - 6.1e-16 58.4 0.0 2e-15 56.7 0.0 1.6 1 1 0 2 2 2 1 Protein of unknown function (DUF3435) UCH PF00443.29 ETS87468.1 - 0.13 11.7 0.4 1.4 8.4 0.2 2.0 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase tRNA_lig_CPD PF08302.11 ETS87468.1 - 0.18 11.2 0.2 0.31 10.5 0.2 1.3 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain DJ-1_PfpI PF01965.24 ETS87469.1 - 2.9e-08 33.7 0.0 5.4e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ETS87469.1 - 7.4e-06 25.8 0.1 0.00018 21.3 0.1 2.2 1 1 0 1 1 1 1 ThiJ/PfpI family-like NmrA PF05368.13 ETS87470.1 - 0.0023 17.5 0.0 0.0033 17.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family SAP PF02037.27 ETS87471.1 - 1.6e-07 30.9 0.0 2.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 SAP domain Sulfatase PF00884.23 ETS87472.1 - 6.9e-61 206.3 0.0 9.6e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 ETS87472.1 - 2.3e-09 38.1 0.0 4.6e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 ETS87472.1 - 4.8e-05 23.1 0.0 0.0035 17.0 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.16 ETS87473.1 - 1.4e-28 99.8 22.0 2.1e-28 99.2 22.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 ETS87475.1 - 4.4e-34 117.7 0.1 7.3e-34 117.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS87475.1 - 1.6e-06 28.2 13.2 2.4e-06 27.6 13.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyrosinase PF00264.20 ETS87476.1 - 5.8e-24 85.6 5.4 5e-17 62.9 0.0 2.2 2 0 0 2 2 2 2 Common central domain of tyrosinase Dioxygenase_C PF00775.21 ETS87477.1 - 1.2e-06 28.1 0.3 2.6e-06 27.0 0.3 1.6 1 1 0 1 1 1 1 Dioxygenase DUF4198 PF10670.9 ETS87477.1 - 0.021 15.2 0.0 0.051 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) SpaA PF17802.1 ETS87477.1 - 0.041 14.2 0.6 0.36 11.2 0.0 2.6 3 0 0 3 3 3 0 Prealbumin-like fold domain OrfB_IS605 PF01385.19 ETS87477.1 - 0.19 11.9 1.4 1 9.6 0.0 2.1 2 0 0 2 2 2 0 Probable transposase Inhibitor_I53 PF11714.8 ETS87477.1 - 0.22 11.8 1.1 1.5 9.1 1.0 2.3 2 0 0 2 2 2 0 Thrombin inhibitor Madanin DJ-1_PfpI PF01965.24 ETS87478.1 - 4e-07 30.0 0.0 1.4e-06 28.2 0.0 1.9 2 1 0 2 2 2 1 DJ-1/PfpI family HET PF06985.11 ETS87480.1 - 9.6e-24 84.4 0.1 1.9e-23 83.4 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cellulase PF00150.18 ETS87481.1 - 7.6e-12 45.2 0.1 1e-11 44.8 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) LGFP PF08310.11 ETS87481.1 - 0.26 11.8 2.6 2.1 8.9 0.7 2.7 2 0 0 2 2 2 0 LGFP repeat DUF1214 PF06742.11 ETS87482.1 - 2.6e-19 69.7 0.0 4.5e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1214) CBFD_NFYB_HMF PF00808.23 ETS87483.1 - 2.9e-10 40.3 0.1 6.8e-10 39.1 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ETS87483.1 - 1.2e-07 32.1 0.1 1.2e-07 32.1 0.1 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 ETS87483.1 - 0.017 15.2 0.2 0.046 13.8 0.1 1.7 1 1 0 1 1 1 0 hTAFII28-like protein conserved region DUF535 PF04393.13 ETS87483.1 - 0.078 12.2 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF535) RNB PF00773.19 ETS87484.1 - 3.4e-98 329.0 0.1 5.6e-98 328.3 0.1 1.4 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 ETS87484.1 - 1.3e-30 106.1 0.0 3.8e-30 104.6 0.0 1.8 1 1 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 ETS87484.1 - 3.5e-30 103.8 0.0 1.3e-29 101.9 0.0 2.1 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 ETS87484.1 - 5.6e-21 74.4 0.0 1.5e-20 73.0 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 ETS87484.1 - 1.8e-10 41.2 0.7 8.2e-10 39.1 0.3 2.3 2 0 0 2 2 2 1 PIN domain CSD2 PF17876.1 ETS87484.1 - 3.3e-10 40.0 0.8 1.6e-05 25.0 0.0 3.4 4 0 0 4 4 4 2 Cold shock domain Dis3l2_C_term PF17877.1 ETS87484.1 - 0.0018 18.6 0.0 0.006 16.9 0.0 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_RNB PF08206.11 ETS87484.1 - 0.075 12.7 1.0 0.92 9.2 0.0 2.8 3 0 0 3 3 3 0 Ribonuclease B OB domain CRC_subunit PF08624.10 ETS87485.1 - 7.1e-52 175.4 0.1 1.3e-51 174.6 0.0 1.4 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit Packaging_FI PF14000.6 ETS87486.1 - 0.085 13.3 1.6 0.14 12.6 1.2 1.5 2 0 0 2 2 2 0 DNA packaging protein FI zf-C4pol PF14260.6 ETS87486.1 - 0.57 10.7 5.4 0.63 10.6 3.4 2.0 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta HAD PF12710.7 ETS87487.1 - 1.3e-15 58.3 0.9 6.7e-15 56.0 0.9 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ETS87487.1 - 0.011 15.8 0.1 4.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETS87487.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase GNAT_acetyltran PF12746.7 ETS87487.1 - 0.069 12.7 0.2 0.74 9.3 0.1 2.0 2 0 0 2 2 2 0 GNAT acetyltransferase DUF812 PF05667.11 ETS87487.1 - 0.1 11.5 0.5 0.14 11.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Hydrolase_3 PF08282.12 ETS87487.1 - 0.25 11.0 0.0 0.25 11.0 0.0 2.2 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase TFIIF_beta PF02270.15 ETS87488.1 - 4e-26 90.9 1.1 6.6e-26 90.2 1.1 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 ETS87488.1 - 6e-26 91.7 0.0 1.3e-25 90.6 0.0 1.6 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus CBF PF03914.17 ETS87489.1 - 2.1e-37 128.8 3.6 1.1e-36 126.5 0.3 2.7 2 1 1 3 3 3 2 CBF/Mak21 family bZIP_1 PF00170.21 ETS87490.1 - 2.3e-05 24.4 12.1 2.3e-05 24.4 12.1 2.6 1 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ETS87490.1 - 0.00022 21.3 8.9 0.00022 21.3 8.9 3.3 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 ETS87490.1 - 0.00048 20.6 9.1 0.00048 20.6 9.1 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF737 PF05300.11 ETS87490.1 - 0.074 13.4 8.2 0.025 14.9 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) DUF1062 PF06353.12 ETS87490.1 - 1.3 9.8 5.9 1.4 9.7 3.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1062) Sel1 PF08238.12 ETS87491.1 - 1.6e-17 63.6 5.6 6.9e-06 26.6 0.0 3.8 4 0 0 4 4 4 3 Sel1 repeat TPR_6 PF13174.6 ETS87491.1 - 0.36 11.6 1.7 8.5 7.3 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 ETS87492.1 - 1.8e-31 109.4 44.5 1.8e-31 109.4 44.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4064 PF13273.6 ETS87492.1 - 0.00079 19.7 0.7 0.00079 19.7 0.7 4.8 3 2 1 4 4 4 1 Protein of unknown function (DUF4064) Transferase PF02458.15 ETS87493.1 - 4.3e-18 65.2 0.0 2.1e-17 62.9 0.0 1.8 2 0 0 2 2 2 1 Transferase family zf-CCCH PF00642.24 ETS87494.1 - 8.6e-13 47.9 21.4 4.6e-05 23.2 0.2 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ETS87494.1 - 1.8e-09 37.3 32.4 5.5e-06 26.2 1.8 5.9 5 1 0 5 5 5 4 Zinc finger domain zf-CCCH_4 PF18044.1 ETS87494.1 - 0.00052 19.7 24.1 0.002 17.9 0.6 4.8 4 1 0 4 4 4 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 ETS87494.1 - 0.0014 18.9 16.2 0.014 15.6 2.7 3.7 1 1 2 3 3 3 2 Zinc-finger containing family Torus PF16131.5 ETS87494.1 - 0.059 14.1 1.3 0.059 14.1 1.3 4.9 2 1 4 6 6 6 0 Torus domain Mt_ATP-synt_B PF05405.14 ETS87495.1 - 2.5e-53 180.0 4.8 3.4e-53 179.6 4.8 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.11 ETS87495.1 - 0.056 13.5 1.2 0.066 13.3 0.3 1.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) DUF3458_C PF17432.2 ETS87495.1 - 0.25 10.7 6.0 3.9 6.8 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3458_C) ARM repeats HECT_2 PF09814.9 ETS87496.1 - 2.7e-92 309.5 0.6 3.1e-92 309.4 0.6 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding RIG-I_C-RD PF11648.8 ETS87496.1 - 0.14 12.4 0.1 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of RIG-I Yippee-Mis18 PF03226.14 ETS87496.1 - 0.2 11.9 3.4 0.7 10.1 3.4 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Questin_oxidase PF14027.6 ETS87497.1 - 8.8e-93 311.5 0.5 1.1e-92 311.3 0.5 1.1 1 0 0 1 1 1 1 Questin oxidase-like Rad17 PF03215.15 ETS87498.1 - 8.6e-28 97.5 0.0 2e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 ETS87498.1 - 2.3e-05 24.8 0.0 8e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS87498.1 - 0.0011 19.3 0.1 0.0039 17.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 ETS87498.1 - 0.0055 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 ETS87498.1 - 0.012 15.6 0.1 0.04 13.9 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 ETS87498.1 - 0.032 14.5 0.0 0.09 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ETS87498.1 - 0.05 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.7 ETS87498.1 - 0.086 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region T2SSE PF00437.20 ETS87498.1 - 0.094 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 ETS87498.1 - 0.098 12.6 0.1 0.29 11.0 0.1 1.8 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 ETS87498.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 ETS87498.1 - 0.19 10.8 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TPT PF03151.16 ETS87499.1 - 4.1e-20 72.3 12.4 5.9e-20 71.8 12.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ETS87499.1 - 0.0002 21.5 34.3 0.0081 16.3 15.0 2.7 2 1 0 2 2 2 2 EamA-like transporter family Nucleo_P87 PF07267.11 ETS87499.1 - 0.84 8.4 8.4 1.2 7.9 8.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CrgA PF06781.12 ETS87499.1 - 1.1 9.3 6.0 1.8 8.7 0.0 3.2 3 0 0 3 3 3 0 Cell division protein CrgA Ycf66_N PF07444.11 ETS87499.1 - 1.5 9.0 6.2 2.9 8.1 0.0 2.9 3 0 0 3 3 3 0 Ycf66 protein N-terminus DAGAT PF03982.13 ETS87500.1 - 3.1e-95 318.5 0.0 4e-95 318.1 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase LAP1C PF05609.12 ETS87500.1 - 1.1 8.3 12.4 1.5 7.8 12.4 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) THOC2_N PF16134.5 ETS87500.1 - 1.5 7.3 13.8 40 2.7 15.3 2.0 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus Peptidase_M22 PF00814.25 ETS87501.1 - 6.5e-48 163.8 0.0 9.7e-25 87.8 0.0 3.6 2 2 0 2 2 2 2 Glycoprotease family Proteasome PF00227.26 ETS87502.1 - 1.9e-48 164.5 0.4 2.2e-48 164.3 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit MFS_1 PF07690.16 ETS87503.1 - 4.7e-30 104.7 39.2 4.7e-30 104.7 39.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Ctr PF04145.15 ETS87504.1 - 5.6e-13 49.7 0.0 8.3e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Ctr copper transporter family Ferric_reduct PF01794.19 ETS87505.1 - 8.5e-21 74.4 13.9 8.5e-21 74.4 13.9 2.7 2 1 1 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ETS87505.1 - 3.1e-14 53.4 0.0 4.7e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ETS87505.1 - 1e-09 38.5 0.0 2.9e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.6 ETS87505.1 - 0.00081 19.9 8.0 0.063 13.8 1.7 3.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4405) Abhydrolase_1 PF00561.20 ETS87506.1 - 1.5e-07 31.3 0.0 2.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS87506.1 - 0.0069 15.7 0.0 0.034 13.4 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S28 PF05577.12 ETS87506.1 - 0.061 12.1 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 RRM_1 PF00076.22 ETS87507.1 - 7.9e-17 60.9 0.0 1.2e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytotoxic PF09000.10 ETS87507.1 - 0.017 15.4 2.1 0.024 15.0 0.1 2.4 3 0 0 3 3 3 0 Cytotoxic Trnau1ap PF17654.1 ETS87507.1 - 0.034 15.0 4.4 0.069 14.0 4.4 1.5 1 0 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins OB_RNB PF08206.11 ETS87507.1 - 0.12 12.1 0.3 0.22 11.2 0.3 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain 6PGD PF00393.19 ETS87508.1 - 7.5e-128 425.9 0.0 9.2e-128 425.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ETS87508.1 - 6.4e-40 136.9 0.0 1e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ETS87508.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ANT PF03374.14 ETS87508.1 - 0.14 12.5 0.0 3.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Phage antirepressor protein KilAC domain PGK PF00162.19 ETS87508.1 - 0.19 10.7 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase SWI-SNF_Ssr4 PF08549.10 ETS87509.1 - 1.7e-256 853.4 1.6 2e-256 853.2 1.6 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Metal_resist PF13801.6 ETS87509.1 - 0.036 14.3 4.3 0.11 12.7 0.1 2.8 2 0 0 2 2 2 0 Heavy-metal resistance PKK PF12474.8 ETS87509.1 - 0.068 13.3 1.5 0.12 12.4 1.5 1.3 1 0 0 1 1 1 0 Polo kinase kinase DUF3704 PF12488.8 ETS87511.1 - 0.15 11.7 2.8 0.84 9.4 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) PI-PLC-X PF00388.19 ETS87512.1 - 2.5e-11 43.4 0.0 4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SET PF00856.28 ETS87513.1 - 6.4e-13 49.4 0.1 5.1e-12 46.5 0.1 2.2 1 1 0 1 1 1 1 SET domain ComZ PF10815.8 ETS87513.1 - 0.018 15.1 0.2 0.051 13.6 0.2 1.7 1 0 0 1 1 1 0 ComZ Peptidase_C69 PF03577.15 ETS87513.1 - 0.17 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C69 Apq12 PF12716.7 ETS87514.1 - 7.2e-11 41.9 13.5 1.2e-10 41.2 13.5 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis TMEM174 PF15029.6 ETS87514.1 - 6.9 6.3 6.3 10 5.7 5.9 1.5 1 1 0 1 1 1 0 Transmembrane protein 174 ATP_bind_1 PF03029.17 ETS87515.1 - 1.5e-73 247.6 0.0 3.2e-73 246.5 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 ETS87515.1 - 0.00032 20.5 0.0 0.0006 19.7 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 ETS87515.1 - 0.00043 20.3 0.0 0.00093 19.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ETS87515.1 - 0.0042 16.8 0.0 0.0083 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETS87515.1 - 0.0047 17.5 0.0 0.026 15.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ETS87515.1 - 0.0059 16.8 0.0 0.03 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ETS87515.1 - 0.0064 16.9 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase CbiA PF01656.23 ETS87515.1 - 0.0074 16.4 0.0 0.0078 16.3 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Septin PF00735.18 ETS87515.1 - 0.021 14.1 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 ETS87515.1 - 0.025 14.9 0.0 0.047 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 ETS87515.1 - 0.03 13.9 0.0 4.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 ETS87515.1 - 0.035 13.6 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 ETS87515.1 - 0.035 14.0 0.1 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase KAP_NTPase PF07693.14 ETS87515.1 - 0.052 12.8 0.0 0.07 12.3 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain SRP54 PF00448.22 ETS87515.1 - 0.053 13.1 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 ETS87515.1 - 0.078 13.3 0.0 0.17 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 ETS87515.1 - 0.087 13.3 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter PPV_E1_C PF00519.17 ETS87515.1 - 0.093 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_17 PF13207.6 ETS87515.1 - 0.1 13.1 0.1 0.63 10.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 ETS87515.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.9 ETS87515.1 - 0.13 12.0 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 ETS87515.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 ETS87515.1 - 0.18 11.4 0.1 14 5.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 ETS87515.1 - 0.2 11.8 0.0 0.62 10.2 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase S-AdoMet_synt_C PF02773.16 ETS87516.1 - 3e-65 218.4 0.4 5.9e-65 217.4 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 ETS87516.1 - 3.2e-44 150.0 0.0 6.5e-44 149.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 ETS87516.1 - 1.9e-43 147.1 0.3 4.4e-43 146.0 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Myb_DNA-bind_6 PF13921.6 ETS87517.1 - 0.00017 21.8 0.1 0.0003 21.0 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain IFT57 PF10498.9 ETS87517.1 - 0.00017 20.7 0.9 0.00022 20.3 0.9 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Myb_DNA-binding PF00249.31 ETS87517.1 - 0.019 15.2 0.6 0.034 14.3 0.6 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain adh_short_C2 PF13561.6 ETS87519.1 - 2.3e-56 191.0 0.0 2.7e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS87519.1 - 5.2e-42 143.5 0.0 6.7e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS87519.1 - 2.1e-10 40.8 0.0 3e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ETS87519.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF4064 PF13273.6 ETS87521.1 - 0.00047 20.4 0.1 0.00055 20.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) DUF1282 PF06930.12 ETS87521.1 - 0.023 14.5 0.1 0.024 14.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Insulin_TMD PF17870.1 ETS87521.1 - 0.075 13.1 2.2 4.2 7.5 0.1 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Aminotran_5 PF00266.19 ETS87523.1 - 1.1e-20 73.9 0.0 2.5e-12 46.5 0.0 2.7 2 1 0 2 2 2 2 Aminotransferase class-V Zn_clus PF00172.18 ETS87524.1 - 6e-08 32.7 8.5 9.7e-08 32.0 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FtsX PF02687.21 ETS87525.1 - 0.0021 18.5 1.1 0.003 18.0 1.1 1.2 1 0 0 1 1 1 1 FtsX-like permease family DUF202 PF02656.15 ETS87525.1 - 0.0041 17.5 8.4 0.026 15.0 8.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF202) Flg_bbr_C PF06429.13 ETS87525.1 - 0.16 12.1 0.7 6.6 6.9 0.1 2.2 2 0 0 2 2 2 0 Flagellar basal body rod FlgEFG protein C-terminal zf-C2H2 PF00096.26 ETS87526.1 - 4.5e-06 26.8 24.4 0.00098 19.4 0.7 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 ETS87526.1 - 0.00065 20.0 4.3 0.016 15.5 3.1 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 ETS87526.1 - 0.0025 17.8 1.0 0.0073 16.3 1.0 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ETS87526.1 - 0.0025 18.5 1.0 0.0025 18.5 1.0 5.0 4 0 0 4 4 4 1 C2H2-type zinc finger TRP PF06011.12 ETS87527.1 - 1.2e-134 449.3 19.8 1.5e-134 448.9 19.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 ETS87527.1 - 5.8e-40 136.9 6.1 1e-39 136.1 6.1 1.4 1 0 0 1 1 1 1 ML-like domain Shisa PF13908.6 ETS87527.1 - 0.0013 19.0 0.1 0.14 12.3 0.2 2.6 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator RRM_1 PF00076.22 ETS87529.1 - 5.4e-06 26.1 0.0 9.2e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 ETS87529.1 - 1.4e-05 25.6 14.4 1.4e-05 25.6 14.4 1.8 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 adh_short PF00106.25 ETS87530.1 - 5.3e-21 75.0 1.3 8.5e-21 74.3 1.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS87530.1 - 1.5e-14 54.1 3.2 2.1e-14 53.7 3.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS87530.1 - 1.5e-09 38.0 0.4 2.9e-09 37.1 0.4 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS87530.1 - 0.068 12.3 0.0 0.29 10.2 0.0 1.9 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Zn_clus PF00172.18 ETS87531.1 - 2e-07 31.0 12.9 2e-07 31.0 12.9 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAN_1 PF00024.26 ETS87532.1 - 1.1e-05 25.2 2.9 7.2e-05 22.7 2.9 2.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 ETS87532.1 - 0.012 15.5 0.7 0.027 14.4 0.7 1.6 1 0 0 1 1 1 0 PAN domain PAN_3 PF08277.12 ETS87532.1 - 0.017 15.0 0.7 0.078 12.8 0.7 2.2 1 0 0 1 1 1 0 PAN-like domain Choline_kinase PF01633.20 ETS87533.1 - 1.9e-53 181.2 0.0 3.5e-52 177.1 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 ETS87533.1 - 1.6e-07 31.5 0.0 4.5e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ETS87533.1 - 0.00041 19.7 0.0 0.00076 18.9 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 ETS87533.1 - 0.059 12.2 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) zf-C2H2 PF00096.26 ETS87534.1 - 0.13 12.8 30.0 1.6 9.3 0.6 7.5 7 0 0 7 7 7 0 Zinc finger, C2H2 type DUF908 PF06012.12 ETS87534.1 - 6 6.2 5.6 1.3 8.4 1.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) zf-C2H2_4 PF13894.6 ETS87534.1 - 7.7 7.7 29.0 1 10.4 0.1 7.3 7 1 0 7 7 7 0 C2H2-type zinc finger CorA PF01544.18 ETS87535.1 - 2.5e-08 33.6 2.5 4.4e-08 32.8 0.9 2.1 2 1 0 3 3 3 1 CorA-like Mg2+ transporter protein Acetyltransf_7 PF13508.7 ETS87536.1 - 2.2e-09 37.6 0.1 2.7e-09 37.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS87536.1 - 5.8e-09 36.2 0.1 7.4e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS87536.1 - 2.1e-06 27.7 0.0 3.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS87536.1 - 8.1e-05 22.5 0.1 0.00017 21.5 0.1 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ETS87536.1 - 0.0083 16.8 0.1 0.01 16.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ETS87536.1 - 0.015 15.4 0.1 0.022 14.9 0.1 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 ETS87536.1 - 0.018 14.7 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SIM_C PF06621.12 ETS87536.1 - 0.057 13.5 0.0 0.071 13.1 0.0 1.1 1 0 0 1 1 1 0 Single-minded protein C-terminus Menin PF05053.13 ETS87537.1 - 5.9 5.1 9.8 7.1 4.9 9.8 1.1 1 0 0 1 1 1 0 Menin MutS_V PF00488.21 ETS87538.1 - 8.5e-47 159.6 0.2 1.4e-46 158.9 0.2 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ETS87538.1 - 8.8e-20 71.7 1.3 1.7e-19 70.8 0.1 2.0 2 1 0 2 2 2 1 MutS domain III DUF3510 PF12022.8 ETS87538.1 - 0.0052 17.2 0.2 0.012 16.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) MutS_IV PF05190.18 ETS87538.1 - 0.13 12.6 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 MutS family domain IV MMgT PF10270.9 ETS87539.1 - 3.2e-35 120.5 0.0 4e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter TolB_N PF04052.13 ETS87540.1 - 0.0068 16.6 0.1 0.01 16.0 0.0 1.4 1 1 0 1 1 1 1 TolB amino-terminal domain AAA PF00004.29 ETS87541.1 - 1.2e-40 139.0 0.0 2.2e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ETS87541.1 - 2.2e-07 30.6 0.0 5.3e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 ETS87541.1 - 6.8e-05 22.9 0.1 0.00043 20.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ETS87541.1 - 0.00011 22.5 0.0 0.0069 16.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 ETS87541.1 - 0.00022 21.4 0.0 0.00083 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 ETS87541.1 - 0.00069 20.0 0.1 0.014 15.8 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 ETS87541.1 - 0.0016 17.7 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 ETS87541.1 - 0.0079 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 ETS87541.1 - 0.024 14.9 0.1 0.063 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ETS87541.1 - 0.034 13.7 0.0 0.097 12.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 ETS87541.1 - 0.048 13.8 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ETS87541.1 - 0.059 13.8 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 ETS87541.1 - 0.078 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ETS87541.1 - 0.097 12.4 0.1 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ETS87541.1 - 0.098 12.4 0.0 0.28 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ETS87541.1 - 0.1 12.7 0.0 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 ETS87541.1 - 0.17 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cpn60_TCP1 PF00118.24 ETS87542.1 - 4e-147 490.8 16.2 4.5e-147 490.6 16.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family STIMATE PF12400.8 ETS87544.1 - 5.7e-41 140.0 6.1 5.7e-41 140.0 6.1 1.5 2 0 0 2 2 2 1 STIMATE family PsbN PF02468.15 ETS87544.1 - 0.017 15.0 0.2 0.067 13.1 0.2 2.0 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) RRM_1 PF00076.22 ETS87545.1 - 6.5e-17 61.1 0.1 1.3e-16 60.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ETS87545.1 - 4.2e-05 23.1 0.0 7.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ETS87545.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Hemolysin_N PF12563.8 ETS87545.1 - 0.15 11.7 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 Hemolytic toxin N terminal DUF2852 PF11014.8 ETS87547.1 - 0.11 12.7 0.9 0.14 12.3 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) Macoilin PF09726.9 ETS87547.1 - 0.37 9.3 8.0 0.41 9.2 8.0 1.0 1 0 0 1 1 1 0 Macoilin family FAM199X PF15814.5 ETS87547.1 - 5.2 6.0 13.7 7.4 5.5 13.7 1.3 1 0 0 1 1 1 0 Protein family FAM199X RCR PF12273.8 ETS87552.1 - 5.6e-26 91.5 8.8 8.5e-26 90.9 8.8 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SARAF PF06682.12 ETS87552.1 - 0.0018 18.0 1.4 0.0018 18.0 1.4 1.7 1 1 1 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis CcmD PF04995.14 ETS87552.1 - 0.076 13.1 1.6 0.13 12.3 1.6 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Hum_adeno_E3A PF05393.11 ETS87552.1 - 0.077 13.0 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF3708 PF12501.8 ETS87552.1 - 0.24 11.2 0.6 0.34 10.7 0.6 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter CAP_N PF01213.19 ETS87552.1 - 7.1 6.0 8.7 10 5.5 8.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RNA_pol_Rpb2_6 PF00562.28 ETS87553.1 - 9.1e-114 380.5 0.1 1.2e-113 380.1 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ETS87553.1 - 8.3e-33 113.6 0.0 1.3e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 ETS87553.1 - 1e-28 99.3 0.0 2.7e-28 98.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 ETS87553.1 - 6.5e-24 84.6 0.0 1.1e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 ETS87553.1 - 5.8e-23 80.7 0.0 1.3e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 ETS87553.1 - 2e-16 60.2 0.0 6.9e-15 55.2 0.0 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 zinc_ribbon_15 PF17032.5 ETS87553.1 - 0.03 15.1 0.5 0.063 14.0 0.5 1.5 1 0 0 1 1 1 0 zinc-ribbon family Tyrosinase PF00264.20 ETS87554.1 - 2e-49 168.9 3.1 3.2e-49 168.2 3.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 ETS87554.1 - 5.3e-24 85.2 0.0 1.4e-23 83.9 0.0 1.7 2 0 0 2 2 2 1 Tyosinase C-terminal domain Ammonium_transp PF00909.21 ETS87555.1 - 1.7e-113 379.4 28.8 1.9e-113 379.2 28.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF441 PF04284.13 ETS87555.1 - 0.008 16.2 0.1 0.036 14.1 0.1 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF441) DNA_pol_B_palm PF14792.6 ETS87556.1 - 4e-35 120.5 0.0 8.3e-35 119.5 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 ETS87556.1 - 9e-23 80.2 0.1 2.1e-22 79.1 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 ETS87556.1 - 6.2e-21 74.0 0.1 1.6e-20 72.6 0.1 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 ETS87556.1 - 2.1e-17 63.3 0.1 6.1e-17 61.7 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 ETS87556.1 - 0.079 13.3 0.2 0.19 12.0 0.2 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain HHH_5 PF14520.6 ETS87556.1 - 0.087 13.4 0.1 2.4 8.8 0.1 2.6 1 1 2 3 3 3 0 Helix-hairpin-helix domain Lum_binding PF00677.17 ETS87557.1 - 2.5e-45 152.3 0.1 1.6e-21 76.0 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain ERCC4 PF02732.15 ETS87558.1 - 1.4e-26 93.6 0.1 3.3e-26 92.4 0.1 1.7 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 ETS87558.1 - 0.0048 17.2 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transferase PF00483.23 ETS87558.1 - 0.024 14.2 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase HTH_45 PF14947.6 ETS87558.1 - 0.078 13.0 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix PadR PF03551.14 ETS87558.1 - 0.088 12.8 0.1 0.41 10.7 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family PGM_PMM_I PF02878.16 ETS87559.1 - 6e-16 58.4 0.2 1.8e-07 31.0 0.0 2.6 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 ETS87559.1 - 1.1e-11 44.7 0.2 5.6e-11 42.5 0.3 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 ETS87559.1 - 0.00052 20.2 0.2 0.0024 18.0 0.1 2.3 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ETS87559.1 - 0.0017 18.9 3.1 0.014 16.0 0.6 3.6 4 1 0 4 4 4 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II CheX PF13690.6 ETS87559.1 - 0.021 15.0 0.1 0.061 13.5 0.0 1.7 2 0 0 2 2 2 0 Chemotaxis phosphatase CheX Methyltransf_25 PF13649.6 ETS87560.1 - 3.3e-11 43.7 0.0 6.9e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS87560.1 - 5.9e-11 42.4 0.0 1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ETS87560.1 - 6.1e-10 39.0 0.0 9.1e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 ETS87560.1 - 3.6e-08 33.9 0.0 1.1e-07 32.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 ETS87560.1 - 7.8e-06 25.0 0.1 1.1e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 ETS87560.1 - 3.6e-05 23.7 0.0 5.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ETS87560.1 - 3.9e-05 23.6 0.1 6.5e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS87560.1 - 0.0003 21.5 0.0 0.00051 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ETS87560.1 - 0.001 18.4 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 ETS87560.1 - 0.0022 17.6 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.16 ETS87560.1 - 0.011 15.6 0.1 0.019 14.8 0.1 1.4 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.6 ETS87560.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 ETS87560.1 - 0.018 14.4 0.2 0.032 13.6 0.2 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PRMT5_C PF17286.2 ETS87560.1 - 0.039 13.8 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain PCMT PF01135.19 ETS87560.1 - 0.053 13.3 0.2 0.077 12.7 0.2 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Per1 PF04080.13 ETS87561.1 - 2.7e-105 351.7 12.6 3.4e-105 351.4 12.6 1.1 1 0 0 1 1 1 1 Per1-like family FAM70 PF14967.6 ETS87561.1 - 0.072 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 FAM70 protein MerC PF03203.14 ETS87561.1 - 0.19 12.2 7.6 0.94 10.0 6.9 2.3 2 0 0 2 2 2 0 MerC mercury resistance protein zf-C2H2 PF00096.26 ETS87562.1 - 0.0043 17.4 2.8 0.0043 17.4 2.8 3.9 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 ETS87562.1 - 0.53 10.4 8.3 7.5 6.7 7.0 2.6 3 0 0 3 3 3 0 Aberrant zinc-finger HET PF06985.11 ETS87565.1 - 3.4e-26 92.4 0.2 6e-26 91.6 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribonuc_L-PSP PF01042.21 ETS87566.1 - 7e-39 132.6 0.0 9.1e-39 132.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP PMT PF02366.18 ETS87567.1 - 7.1e-83 277.9 15.9 1.1e-82 277.4 15.9 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ETS87567.1 - 8.5e-69 231.1 8.6 8.5e-69 231.1 8.6 3.2 2 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ETS87567.1 - 1.6e-17 64.0 0.1 4.7e-17 62.4 0.0 1.7 1 1 1 2 2 2 2 MIR domain FAA_hydrolase PF01557.18 ETS87568.1 - 5.6e-46 156.9 0.0 6.9e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family UBA PF00627.31 ETS87569.1 - 0.073 13.0 0.8 0.25 11.3 1.0 1.9 2 1 0 2 2 2 0 UBA/TS-N domain PWI PF01480.17 ETS87570.1 - 2.4e-29 101.5 0.1 3.7e-29 100.8 0.1 1.3 1 0 0 1 1 1 1 PWI domain NuA4 PF09340.10 ETS87571.1 - 8.2e-22 76.9 0.1 8.2e-22 76.9 0.1 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 KELK PF15796.5 ETS87571.1 - 0.057 13.9 0.6 0.057 13.9 0.6 2.2 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase dbPDZ_assoc PF16610.5 ETS87571.1 - 0.065 13.5 4.1 0.14 12.4 4.1 1.5 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 MAP70 PF07058.11 ETS87571.1 - 1.2 7.8 8.0 1.6 7.4 0.2 2.0 1 1 1 2 2 2 0 Microtubule-associated protein 70 Peptidase_S9 PF00326.21 ETS87572.1 - 8.2e-57 192.1 0.1 2.1e-56 190.7 0.1 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 ETS87572.1 - 0.0012 17.6 0.6 0.061 12.0 0.1 2.5 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF2721 PF11026.8 ETS87573.1 - 0.009 15.9 0.1 0.009 15.9 0.1 3.2 3 1 1 4 4 4 1 Protein of unknown function (DUF2721) DUF1664 PF07889.12 ETS87573.1 - 0.017 15.1 3.8 0.017 15.1 3.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) RFamide_26RFa PF11109.8 ETS87573.1 - 0.081 13.4 0.2 0.081 13.4 0.2 2.8 2 1 0 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 BLOC1_2 PF10046.9 ETS87573.1 - 2.7 8.3 10.9 7.3 7.0 2.9 3.0 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0242 PF06785.11 ETS87573.1 - 4 7.5 24.7 0.3 11.2 15.0 2.9 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Ammonium_transp PF00909.21 ETS87574.1 - 1.8e-116 389.2 28.9 2e-116 389.0 28.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF373 PF04123.13 ETS87574.1 - 2.7 7.4 5.4 0.44 9.9 0.8 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF373) CRT10 PF08728.10 ETS87575.1 - 3.9e-16 58.4 0.0 1.8e-07 29.8 0.0 2.7 3 1 0 3 3 3 2 CRT10 Zn_clus PF00172.18 ETS87577.1 - 0.081 13.1 6.0 0.17 12.1 6.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 ETS87578.1 - 2.8e-29 102.7 0.5 3.7e-29 102.3 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 ETS87578.1 - 0.011 14.9 0.1 0.016 14.3 0.1 1.2 1 0 0 1 1 1 0 CsiD SLATT_5 PF18160.1 ETS87580.1 - 7.7 5.8 11.9 0.099 12.0 0.9 3.0 3 1 1 4 4 4 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF3144 PF11342.8 ETS87583.1 - 0.056 13.7 1.4 0.19 12.1 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3144) DUF1771 PF08590.10 ETS87584.1 - 4.4e-15 55.8 11.5 8.9e-15 54.8 11.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 ETS87584.1 - 3.5e-08 33.7 0.0 9.6e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Smr domain zf_CCCH_4 PF18345.1 ETS87584.1 - 8.6e-08 32.0 7.9 1.1e-05 25.4 0.4 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 ETS87584.1 - 1.1e-05 25.1 1.6 0.008 16.1 0.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 ETS87584.1 - 0.00018 21.8 3.9 0.21 12.1 0.6 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 ETS87584.1 - 0.00098 18.9 10.0 0.0087 15.8 0.3 3.0 2 1 0 2 2 2 1 CCCH-type zinc finger HBS1_N PF08938.10 ETS87584.1 - 0.0068 16.7 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 HBS1 N-terminus zf-CCCH_3 PF15663.5 ETS87584.1 - 0.34 11.1 3.0 8.6 6.6 0.2 2.2 1 1 1 2 2 2 0 Zinc-finger containing family Torus PF16131.5 ETS87584.1 - 0.5 11.1 5.1 1 10.1 0.8 2.5 1 1 1 2 2 2 0 Torus domain Cupin_8 PF13621.6 ETS87585.1 - 2.2e-17 63.6 0.0 1e-15 58.2 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 ETS87585.1 - 9.6e-11 42.1 0.0 2.3e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 ETS87585.1 - 2.2e-07 30.7 0.1 4.8e-06 26.4 0.2 2.7 3 0 0 3 3 3 1 F-box-like Cupin_4 PF08007.12 ETS87585.1 - 9.5e-05 22.0 0.0 0.00022 20.8 0.0 1.5 2 0 0 2 2 2 1 Cupin superfamily protein F-box PF00646.33 ETS87585.1 - 0.0017 18.2 0.2 0.0048 16.8 0.2 1.8 1 0 0 1 1 1 1 F-box domain DEAD PF00270.29 ETS87586.1 - 8.1e-46 156.0 0.9 1.3e-45 155.3 0.9 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS87586.1 - 5.6e-32 110.4 0.1 8.7e-31 106.5 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS87586.1 - 3.5e-06 27.1 0.0 5.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ETS87586.1 - 0.0004 20.2 0.1 0.00079 19.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ETS87586.1 - 0.0011 19.3 0.8 0.0073 16.7 0.3 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ETS87586.1 - 0.016 15.5 0.6 0.091 13.0 0.6 2.2 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 ETS87586.1 - 0.023 14.0 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit fragilysinNterm PF16376.5 ETS87586.1 - 0.047 13.4 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of fragilysin IL17R_D_N PF16742.5 ETS87586.1 - 0.096 12.7 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Helicase_RecD PF05127.14 ETS87586.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Helicase tRNA-synt_1 PF00133.22 ETS87587.1 - 7.1e-223 741.2 0.3 7.1e-223 741.2 0.3 2.8 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ETS87587.1 - 3.6e-36 124.4 0.5 1.1e-35 122.8 0.5 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ETS87587.1 - 4.9e-11 42.0 0.3 0.0017 17.2 0.0 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 ETS87587.1 - 9.3e-09 35.1 0.0 9.3e-09 35.1 0.0 3.6 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 ETS87587.1 - 0.00055 20.2 5.5 0.00055 20.2 5.5 3.7 4 0 0 4 4 4 1 Valyl tRNA synthetase tRNA binding arm EMP24_GP25L PF01105.24 ETS87587.1 - 0.043 13.7 0.2 0.14 12.1 0.2 1.8 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD tRNA-synt_1e PF01406.19 ETS87587.1 - 0.92 8.8 0.0 0.92 8.8 0.0 2.8 4 0 0 4 4 4 0 tRNA synthetases class I (C) catalytic domain EPL1 PF10513.9 ETS87587.1 - 3.9 7.8 7.6 0.64 10.4 0.6 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like Drc1-Sld2 PF11719.8 ETS87588.1 - 2.8e-05 23.9 7.4 2.8e-05 23.9 7.4 2.3 2 1 0 2 2 2 1 DNA replication and checkpoint protein Nop14 PF04147.12 ETS87588.1 - 0.0055 15.0 20.9 0.013 13.8 20.9 1.5 1 0 0 1 1 1 1 Nop14-like family YL1 PF05764.13 ETS87588.1 - 0.011 15.9 26.6 0.011 15.9 26.6 3.3 2 1 1 3 3 3 0 YL1 nuclear protein DUF913 PF06025.12 ETS87588.1 - 0.38 9.7 3.1 0.91 8.4 3.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SR-25 PF10500.9 ETS87588.1 - 3.6 7.1 26.9 1.8 8.1 10.9 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Sigma70_ner PF04546.13 ETS87588.1 - 7.4 6.4 17.5 28 4.5 17.5 2.0 1 0 0 1 1 1 0 Sigma-70, non-essential region Pes-10 PF07149.11 ETS87588.1 - 7.7 5.5 13.0 13 4.8 13.0 1.2 1 0 0 1 1 1 0 Pes-10 His_Phos_1 PF00300.22 ETS87589.1 - 2e-10 40.7 0.0 2.7e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Stk19 PF10494.9 ETS87590.1 - 4.4e-77 259.1 0.0 5.3e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Edc3_linker PF16598.5 ETS87590.1 - 0.0018 18.9 1.0 0.0045 17.6 1.0 1.6 1 0 0 1 1 1 1 Linker region of enhancer of mRNA-decapping protein 3 Kinesin PF00225.23 ETS87591.1 - 2.8e-96 322.3 0.0 2.8e-96 322.3 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ETS87591.1 - 8.3e-21 74.5 0.0 4.1e-20 72.2 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 ETS87591.1 - 0.045 13.6 0.2 0.045 13.6 0.2 3.5 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TFB6 PF17110.5 ETS87591.1 - 0.61 9.8 5.8 2.1 8.1 5.5 2.0 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Phage_Gp23 PF10669.9 ETS87591.1 - 0.66 10.3 3.4 1.9 8.8 3.4 1.7 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF4407 PF14362.6 ETS87591.1 - 1.5 8.1 16.7 0.29 10.5 4.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cytochrom_NNT PF03264.14 ETS87592.1 - 0.056 13.1 0.1 0.095 12.4 0.1 1.3 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region SH3BGR PF04908.15 ETS87593.1 - 0.0002 21.4 0.0 0.00053 20.1 0.0 1.8 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein ATP11 PF06644.11 ETS87593.1 - 3.7 7.3 6.5 0.59 9.9 2.2 1.8 2 0 0 2 2 2 0 ATP11 protein SNARE_assoc PF09335.11 ETS87594.1 - 1.7e-14 54.4 6.9 1.7e-14 54.4 6.9 2.4 2 1 1 3 3 3 1 SNARE associated Golgi protein Gram_pos_anchor PF00746.21 ETS87594.1 - 5.8 7.0 11.5 0.95 9.5 0.3 3.3 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Abhydrolase_6 PF12697.7 ETS87595.1 - 1.3e-19 71.7 2.8 1.7e-19 71.3 2.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS87595.1 - 4.4e-11 42.9 0.1 1.3e-10 41.4 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS87595.1 - 5.5e-06 25.8 0.1 0.0048 16.2 0.0 2.3 2 1 0 2 2 2 2 Serine aminopeptidase, S33 p450 PF00067.22 ETS87597.1 - 3.5e-73 246.9 0.0 4.3e-73 246.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Get5_bdg PF16843.5 ETS87597.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein DUF3074 PF11274.8 ETS87598.1 - 3.7e-48 163.9 0.0 4.6e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) K_channel_TID PF07941.11 ETS87598.1 - 8.8 6.9 12.8 2.1 8.9 0.1 3.0 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Ofd1_CTDD PF10637.9 ETS87599.1 - 2.1e-99 332.1 0.0 2e-93 312.4 0.1 2.6 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 ETS87599.1 - 6.1e-26 90.9 0.0 2e-25 89.3 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 ETS87599.1 - 2e-12 47.8 0.0 4.9e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aminotran_5 PF00266.19 ETS87600.1 - 6e-61 206.4 0.0 9.3e-61 205.8 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ETS87600.1 - 2.3e-05 23.1 0.0 3.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ETS87600.1 - 0.0028 16.9 0.0 0.0052 16.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Ribul_P_3_epim PF00834.19 ETS87601.1 - 4.9e-63 212.1 0.0 2.3e-62 209.9 0.0 1.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 ETS87601.1 - 0.061 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.14 ETS87601.1 - 0.12 11.6 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG eIF-3_zeta PF05091.12 ETS87602.1 - 7.5e-208 691.7 0.0 8.8e-208 691.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.13 ETS87602.1 - 0.0085 15.8 0.1 0.035 13.8 0.1 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF569) CDC48_2 PF02933.17 ETS87602.1 - 0.063 13.1 0.0 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 PAP1 PF08601.10 ETS87603.1 - 0.071 12.8 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 bZIP_1 PF00170.21 ETS87604.1 - 8.5e-06 25.8 8.9 1.4e-05 25.1 8.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor NUDE_C PF04880.13 ETS87604.1 - 0.00098 19.6 5.4 0.0015 19.1 5.4 1.3 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region Nucleo_P87 PF07267.11 ETS87604.1 - 0.022 13.6 2.7 0.026 13.4 2.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 bZIP_2 PF07716.15 ETS87604.1 - 0.37 10.9 11.4 2.7 8.1 11.4 2.1 1 1 0 1 1 1 0 Basic region leucine zipper Acyltransferase PF01553.21 ETS87605.1 - 9.8e-14 51.1 0.0 1.4e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 ETS87605.1 - 2e-10 40.6 2.3 9e-10 38.5 0.2 2.4 2 0 0 2 2 2 1 Acyltransferase C-terminus DUF3027 PF11228.8 ETS87605.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) Pkinase PF00069.25 ETS87606.1 - 2.3e-60 204.2 0.0 9.7e-39 133.3 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS87606.1 - 2.3e-27 95.9 0.1 5.2e-21 75.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 ETS87606.1 - 1.5e-14 54.1 0.0 3e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 ETS87606.1 - 1.5e-07 31.1 0.0 7.9e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 ETS87606.1 - 3.4e-05 23.9 0.4 0.0028 17.6 0.1 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family PAS_9 PF13426.7 ETS87606.1 - 0.0065 16.7 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 PAS domain Haspin_kinase PF12330.8 ETS87606.1 - 0.0075 15.2 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ETS87606.1 - 0.0093 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS PF00989.25 ETS87606.1 - 0.013 15.5 0.0 0.05 13.6 0.0 2.0 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.11 ETS87606.1 - 0.028 13.5 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 ETS87606.1 - 0.11 12.1 0.0 13 5.4 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 HLH PF00010.26 ETS87607.1 - 5.4e-16 58.3 0.3 1.2e-15 57.2 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4407 PF14362.6 ETS87607.1 - 3.2 7.0 8.3 5.5 6.2 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 ETS87607.1 - 9.9 5.4 14.5 2.6 7.3 3.1 2.8 3 0 0 3 3 3 0 FAM76 protein MSC PF09402.10 ETS87608.1 - 2.4e-117 392.2 0.0 3.5e-117 391.7 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 ETS87608.1 - 2.6e-16 59.0 0.0 4.6e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.11 ETS87608.1 - 0.00069 19.2 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Thymopoietin protein Endonuc-dimeris PF09124.10 ETS87608.1 - 0.0061 16.7 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 T4 recombination endonuclease VII, dimerisation TMEM154 PF15102.6 ETS87609.1 - 0.002 18.1 0.0 0.0059 16.5 0.0 1.8 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 ETS87609.1 - 0.0045 16.8 0.0 0.0076 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Rax2 PF12768.7 ETS87609.1 - 0.087 12.3 9.2 2.4 7.6 2.2 3.1 2 2 1 3 3 3 0 Cortical protein marker for cell polarity UL45 PF05473.12 ETS87609.1 - 0.11 12.2 0.2 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Stevor PF17410.2 ETS87609.1 - 0.21 11.1 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TAP_C PF03943.13 ETS87610.1 - 3.8e-18 64.9 0.5 1.5e-17 63.0 0.6 2.0 2 0 0 2 2 2 1 TAP C-terminal domain RRM_9 PF18444.1 ETS87610.1 - 2.8e-06 27.1 0.1 1.2e-05 25.1 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif NTF2 PF02136.20 ETS87610.1 - 0.00052 20.6 0.2 0.0033 18.0 0.2 2.2 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_9 PF14580.6 ETS87610.1 - 0.062 12.8 0.1 0.63 9.5 0.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeat LRR_4 PF12799.7 ETS87610.1 - 0.065 13.7 3.8 0.33 11.4 0.3 2.6 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) ResIII PF04851.15 ETS87611.1 - 3.6e-24 85.7 0.0 8.1e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ETS87611.1 - 1.5e-21 76.8 0.1 4.8e-21 75.2 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ETS87611.1 - 8.5e-18 64.7 0.0 3.1e-17 62.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ETS87611.1 - 0.0013 19.0 0.0 0.0058 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF218 PF02698.17 ETS87611.1 - 0.034 14.2 0.1 0.12 12.4 0.1 1.9 1 0 0 1 1 1 0 DUF218 domain DUF2002 PF09400.10 ETS87611.1 - 0.14 12.2 0.2 0.63 10.1 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2002) RNB PF00773.19 ETS87613.1 - 2.1e-55 188.4 0.0 3.4e-55 187.7 0.0 1.3 1 0 0 1 1 1 1 RNB domain Med3 PF11593.8 ETS87614.1 - 8 5.5 13.8 9.7 5.3 13.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Glyco_hydro_17 PF00332.18 ETS87615.1 - 0.018 14.6 0.1 0.064 12.8 0.1 1.9 1 1 0 1 1 1 0 Glycosyl hydrolases family 17 DUF5049 PF16468.5 ETS87615.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5049) WD40 PF00400.32 ETS87616.1 - 2.9e-05 24.7 0.3 2.9e-05 24.7 0.3 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF2415 PF10313.9 ETS87616.1 - 0.088 12.7 0.0 0.32 11.0 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Chitin_synth_2 PF03142.15 ETS87618.1 - 2.6e-289 960.2 0.1 4e-289 959.6 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 ETS87618.1 - 1.2e-11 44.9 2.9 5.4e-11 42.8 2.9 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ETS87618.1 - 4.8e-10 39.7 0.1 1.4e-08 34.9 0.0 2.9 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ETS87618.1 - 0.00088 18.8 0.1 0.007 15.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ETS87618.1 - 0.061 13.1 0.0 0.31 10.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 NepR PF18557.1 ETS87618.1 - 0.069 12.8 0.2 17 5.2 0.0 2.4 2 0 0 2 2 2 0 Anti-sigma factor NepR Wzy_C PF04932.15 ETS87618.1 - 0.13 11.9 0.1 27 4.4 0.4 3.0 3 0 0 3 3 3 0 O-Antigen ligase Wzz PF02706.15 ETS87618.1 - 1 9.7 3.1 1.7 9.0 0.3 2.5 2 0 0 2 2 2 0 Chain length determinant protein Sel1 PF08238.12 ETS87619.1 - 2.9e-40 135.8 26.6 2.5e-05 24.8 0.2 7.4 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 ETS87619.1 - 0.13 13.0 1.2 4 8.3 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_S64 PF08192.11 ETS87619.1 - 7.6 4.9 8.0 11 4.4 8.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Pkinase PF00069.25 ETS87620.1 - 5.3e-66 222.7 0.0 7.4e-66 222.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS87620.1 - 8.6e-42 143.2 0.1 1.4e-41 142.5 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 ETS87620.1 - 1e-06 28.8 0.1 0.00081 19.5 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 ETS87620.1 - 2.1e-05 24.0 0.0 3.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ETS87620.1 - 0.0011 18.3 0.1 0.0021 17.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ETS87620.1 - 0.013 14.3 0.2 0.025 13.3 0.2 1.4 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 ETS87620.1 - 0.034 13.1 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain OPA3 PF07047.12 ETS87621.1 - 1.5e-44 150.8 0.4 2e-44 150.3 0.4 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF4407 PF14362.6 ETS87621.1 - 0.018 14.4 1.5 0.025 14.0 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med21 PF11221.8 ETS87621.1 - 0.098 12.9 10.5 0.16 12.2 3.5 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex MAP17 PF15807.5 ETS87621.1 - 0.28 11.4 2.4 18 5.5 0.7 2.2 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4140 PF13600.6 ETS87621.1 - 0.32 11.4 0.2 0.32 11.4 0.2 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) SBDS PF01172.18 ETS87623.1 - 8.9e-25 86.6 0.3 1.1e-24 86.3 0.3 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RhoGEF PF00621.20 ETS87624.1 - 3.3e-22 79.6 0.0 5.9e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain Nas2_N PF18265.1 ETS87625.1 - 2.1e-29 101.3 0.1 3e-29 100.8 0.1 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 ETS87625.1 - 3.3e-08 33.2 0.0 5.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 ETS87625.1 - 6.5e-06 26.4 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 ETS87625.1 - 7.1e-05 23.1 0.0 0.00014 22.2 0.0 1.4 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 ETS87625.1 - 0.00016 22.0 0.0 0.00027 21.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Ras PF00071.22 ETS87626.1 - 3.8e-49 166.4 0.0 4.6e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ETS87626.1 - 6.6e-30 103.8 0.1 1.7e-29 102.5 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ETS87626.1 - 9e-11 41.5 0.0 1.1e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 ETS87626.1 - 0.00044 20.6 0.1 0.0038 17.6 0.1 2.2 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 ETS87626.1 - 0.00068 19.7 0.0 0.0013 18.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ETS87626.1 - 0.0024 17.3 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 ETS87626.1 - 0.013 15.0 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 ETS87626.1 - 0.016 14.8 0.1 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 ETS87626.1 - 0.017 15.0 0.2 4.8 7.0 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 ETS87626.1 - 0.018 14.2 2.7 0.66 9.1 0.2 2.6 2 1 1 3 3 3 0 G-protein alpha subunit AAA_24 PF13479.6 ETS87626.1 - 0.058 13.1 0.1 0.089 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 ETS87626.1 - 0.059 12.8 0.0 0.1 12.0 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TsaE PF02367.17 ETS87626.1 - 0.069 13.1 0.2 0.15 12.1 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 ETS87626.1 - 0.096 13.1 0.2 0.21 11.9 0.1 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 ETS87626.1 - 0.11 12.7 0.2 0.2 11.8 0.2 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 ETS87626.1 - 0.15 11.3 0.7 0.2 10.9 0.1 1.5 2 0 0 2 2 2 0 Septin E1-E2_ATPase PF00122.20 ETS87627.1 - 1.3e-49 168.2 4.8 2.3e-49 167.3 1.4 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ETS87627.1 - 4.3e-47 160.2 6.6 4.3e-47 160.2 6.6 1.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ETS87627.1 - 6.8e-23 82.0 1.3 3.9e-22 79.6 1.3 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ETS87627.1 - 2.5e-20 72.3 0.0 4.8e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ETS87627.1 - 5.1e-19 67.7 0.1 1.6e-18 66.1 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ETS87627.1 - 9.2e-09 35.4 1.1 2.7e-06 27.3 1.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ETS87627.1 - 6.9e-05 23.3 0.0 0.00027 21.4 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Proteasome PF00227.26 ETS87628.1 - 3.6e-36 124.4 0.0 4e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.8 ETS87629.1 - 4.7e-24 84.4 0.1 9.6e-24 83.4 0.1 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain Rad60-SLD PF11976.8 ETS87629.1 - 4.9e-05 23.1 0.1 0.00042 20.1 0.1 2.5 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like RA PF00788.23 ETS87629.1 - 0.0032 18.1 0.2 0.0081 16.8 0.2 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain RBD PF02196.15 ETS87629.1 - 0.0033 17.5 0.1 0.032 14.3 0.1 2.3 2 0 0 2 2 2 1 Raf-like Ras-binding domain DUF3275 PF11679.8 ETS87629.1 - 0.1 12.6 5.1 0.21 11.5 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Cobl PF09469.10 ETS87629.1 - 0.28 11.5 0.9 0.51 10.6 0.0 1.9 2 0 0 2 2 2 0 Cordon-bleu ubiquitin-like domain AltA1 PF16541.5 ETS87630.1 - 7.7e-05 23.5 7.1 0.00012 22.9 6.9 1.4 1 1 0 1 1 1 1 Alternaria alternata allergen 1 Lipase_3 PF01764.25 ETS87631.1 - 1e-30 106.4 0.0 1.4e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ETS87631.1 - 1e-05 26.3 0.4 1.8e-05 25.5 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS87631.1 - 9.3e-05 21.8 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 ETS87631.1 - 0.0027 17.3 0.0 0.027 14.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) PGAP1 PF07819.13 ETS87631.1 - 0.047 13.4 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 ETS87631.1 - 0.056 13.1 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 ETS87631.1 - 0.14 12.2 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain 14-3-3 PF00244.20 ETS87632.1 - 4.7e-100 333.7 1.0 5.6e-100 333.4 1.0 1.1 1 0 0 1 1 1 1 14-3-3 protein Ribosomal_60s PF00428.19 ETS87632.1 - 0.094 13.3 10.4 0.23 12.1 5.8 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein PhnJ PF06007.11 ETS87633.1 - 0.073 12.1 0.6 0.12 11.4 0.6 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ SUIM_assoc PF16619.5 ETS87633.1 - 0.13 12.3 12.3 1.7 8.7 1.5 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 ETS87633.1 - 1 8.9 8.0 0.49 10.0 5.9 1.4 2 0 0 2 2 2 0 Spt20 family Syja_N PF02383.18 ETS87634.1 - 5.7e-76 255.9 0.1 1.1e-75 254.9 0.0 1.5 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 ETS87634.1 - 1.3e-10 41.2 0.0 2.7e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_14 PF13428.6 ETS87635.1 - 2.2e-06 28.0 11.5 0.033 15.0 0.1 6.5 5 2 1 6 6 6 2 Tetratricopeptide repeat Suf PF05843.14 ETS87635.1 - 4.6e-06 26.8 7.8 0.0061 16.6 0.1 3.2 3 0 0 3 3 3 3 Suppressor of forked protein (Suf) peroxidase PF00141.23 ETS87636.1 - 1.8e-48 165.2 0.0 3.7e-48 164.2 0.0 1.5 1 0 0 1 1 1 1 Peroxidase zf-LYAR PF08790.11 ETS87637.1 - 3.5e-08 33.2 0.5 9.2e-08 31.9 0.5 1.8 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Ferlin_C PF16165.5 ETS87637.1 - 2.9 7.8 7.0 0.66 9.9 2.4 2.2 2 0 0 2 2 2 0 Ferlin C-terminus Pol_alpha_B_N PF08418.10 ETS87637.1 - 6.5 6.6 17.8 8.4 6.3 6.3 2.6 2 1 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Hydrolase_4 PF12146.8 ETS87638.1 - 7.3e-17 61.4 0.0 5e-12 45.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ETS87638.1 - 2.1e-10 40.7 0.1 1.8e-07 31.1 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF818 PF05677.12 ETS87638.1 - 9e-06 24.9 0.1 1.2e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_6 PF12697.7 ETS87638.1 - 3e-05 24.7 0.0 5.9e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 ETS87638.1 - 3.1e-05 22.8 0.1 0.014 14.1 0.1 2.7 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) DLH PF01738.18 ETS87638.1 - 0.00016 21.3 0.0 0.0022 17.6 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 ETS87638.1 - 0.00021 21.0 0.0 0.00059 19.5 0.0 1.7 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 ETS87638.1 - 0.00026 20.5 0.0 0.031 13.8 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 ETS87638.1 - 0.0013 18.7 0.0 0.074 13.0 0.0 2.4 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 ETS87638.1 - 0.0045 16.9 0.0 0.0086 16.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 ETS87638.1 - 0.025 14.4 0.1 2.5 7.9 0.1 2.3 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.13 ETS87638.1 - 0.027 13.0 0.0 0.043 12.3 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.7 ETS87638.1 - 0.074 12.8 0.0 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 ETS87638.1 - 0.083 12.6 0.4 1 9.0 0.1 2.2 1 1 1 2 2 2 0 PGAP1-like protein Esterase PF00756.20 ETS87638.1 - 0.15 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF1057 PF06342.12 ETS87638.1 - 0.17 10.9 0.1 0.24 10.4 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) R3H PF01424.22 ETS87639.1 - 1.9e-15 56.6 0.1 3.3e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 R3H domain Zf_RING PF16744.5 ETS87641.1 - 3.1e-05 24.0 6.6 4.8e-05 23.4 6.6 1.3 1 0 0 1 1 1 1 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 ETS87641.1 - 4.8e-05 22.9 3.7 9.1e-05 22.0 3.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type PHD PF00628.29 ETS87641.1 - 0.00019 21.2 7.4 0.0003 20.6 7.4 1.3 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 ETS87641.1 - 0.00052 19.9 4.3 0.0064 16.4 2.8 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD_4 PF16866.5 ETS87641.1 - 0.00098 19.2 10.4 0.0068 16.5 10.4 2.1 1 1 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 ETS87641.1 - 0.0011 19.2 6.4 0.0018 18.5 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain C1_2 PF03107.16 ETS87641.1 - 0.0014 18.8 1.7 0.0014 18.8 1.7 1.8 2 0 0 2 2 2 1 C1 domain C1_1 PF00130.22 ETS87641.1 - 0.062 13.2 7.3 0.049 13.5 3.6 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FANCL_C PF11793.8 ETS87641.1 - 0.12 12.6 5.3 0.19 11.9 5.3 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Eapp_C PF10238.9 ETS87641.1 - 2.3 8.3 5.5 26 4.8 0.6 3.1 1 1 2 3 3 3 0 E2F-associated phosphoprotein RINGv PF12906.7 ETS87641.1 - 2.4 8.3 9.2 4.4 7.5 9.2 1.5 1 0 0 1 1 1 0 RING-variant domain WSC PF01822.19 ETS87642.1 - 5.6e-85 279.6 91.4 3e-18 65.8 16.9 5.8 5 0 0 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.11 ETS87642.1 - 1.6e-23 83.2 0.0 3.9e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 ETS87642.1 - 4.1e-22 78.3 0.0 1.4e-21 76.6 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 ETS87642.1 - 0.41 10.7 1.9 9.5 6.4 0.0 3.9 4 0 0 4 4 4 0 Kelch motif RSN1_7TM PF02714.15 ETS87643.1 - 3.5e-77 259.4 21.9 5.3e-77 258.8 21.9 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ETS87643.1 - 3.9e-42 143.7 1.1 3.9e-42 143.7 1.1 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ETS87643.1 - 1.6e-39 136.0 0.0 2.2e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter TMF_TATA_bd PF12325.8 ETS87643.1 - 0.24 11.6 0.0 0.43 10.8 0.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Glyco_hydro_6 PF01341.17 ETS87644.1 - 2.6e-97 326.2 0.6 3.4e-97 325.9 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 SLD3 PF08639.10 ETS87645.1 - 3.9e-159 530.9 16.8 6.2e-159 530.2 16.8 1.3 1 0 0 1 1 1 1 DNA replication regulator SLD3 Pkinase PF00069.25 ETS87646.1 - 9.9e-68 228.4 0.0 1.7e-67 227.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS87646.1 - 4.6e-37 127.7 0.0 8.3e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS87646.1 - 1.3e-05 24.7 0.0 2.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ETS87646.1 - 0.012 14.4 0.0 0.024 13.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 ETS87646.1 - 0.014 15.4 0.6 0.042 13.8 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ETS87646.1 - 0.06 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 NOG1_N PF17835.1 ETS87646.1 - 0.18 11.7 0.1 0.18 11.7 0.1 3.2 3 1 0 3 3 3 0 NOG1 N-terminal helical domain GN3L_Grn1 PF08701.11 ETS87647.1 - 3.9e-26 90.9 18.3 9.1e-26 89.8 18.3 1.7 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 ETS87647.1 - 2.2e-16 60.0 0.0 1.1e-12 48.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ETS87647.1 - 4.6e-08 33.1 0.1 3.2e-07 30.4 0.1 2.0 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 ETS87647.1 - 9.8e-05 22.0 0.0 0.24 10.9 0.0 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ETS87647.1 - 0.00013 22.0 5.2 0.22 11.5 0.2 3.9 4 0 0 4 4 4 2 Dynamin family FeoB_N PF02421.18 ETS87647.1 - 0.00041 19.9 0.1 0.0058 16.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B cobW PF02492.19 ETS87647.1 - 0.00094 18.8 0.0 0.17 11.4 0.0 2.9 2 1 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain PGA2 PF07543.12 ETS87647.1 - 0.0011 18.9 14.2 0.0011 18.9 14.2 2.7 2 1 1 3 3 3 2 Protein trafficking PGA2 MeaB PF03308.16 ETS87647.1 - 0.011 14.7 0.0 0.011 14.7 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 ETS87647.1 - 0.041 14.3 0.0 0.041 14.3 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain HAD_2 PF13419.6 ETS87648.1 - 1.1e-19 71.1 0.0 1.9e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ETS87648.1 - 1.1e-09 38.9 0.0 2.4e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ETS87648.1 - 0.00011 22.2 0.0 0.0003 20.8 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 ETS87648.1 - 0.00013 22.4 0.0 0.00021 21.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ETS87648.1 - 0.074 13.2 0.0 15 5.7 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Homeodomain PF00046.29 ETS87649.1 - 1.4e-16 60.0 1.1 3.2e-16 58.9 1.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ETS87649.1 - 4.2e-05 23.4 0.2 0.0001 22.1 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 ETS87649.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT COesterase PF00135.28 ETS87650.1 - 5.1e-83 279.7 0.0 7e-83 279.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS87650.1 - 5.2e-06 26.5 0.1 4.5e-05 23.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold HLH PF00010.26 ETS87651.1 - 1.3e-12 47.5 0.2 2.6e-12 46.5 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TMEM70 PF06979.12 ETS87653.1 - 0.023 15.1 1.2 0.023 15.1 1.2 1.7 2 0 0 2 2 2 0 Assembly, mitochondrial proton-transport ATP synth complex Med16 PF11635.8 ETS87654.1 - 2.1e-71 240.9 0.5 3e-71 240.4 0.5 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 DUF3819 PF12842.7 ETS87654.1 - 0.034 14.1 0.1 0.095 12.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) SIR2 PF02146.17 ETS87655.1 - 4.7e-29 101.6 0.1 5.8e-28 98.0 0.1 2.1 1 1 0 1 1 1 1 Sir2 family CNOT1_TTP_bind PF16417.5 ETS87655.1 - 0.1 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 TTP binding domain SNF2_N PF00176.23 ETS87656.1 - 1.1e-57 195.3 0.0 1.9e-57 194.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 ETS87656.1 - 8.3e-22 76.9 11.0 6.5e-16 58.0 0.4 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 ETS87656.1 - 3.4e-18 66.0 0.0 8e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 ETS87656.1 - 1.8e-10 41.1 0.0 8.2e-10 39.0 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) HDA2-3 PF11496.8 ETS87656.1 - 5.5e-09 35.6 0.4 3.2e-08 33.1 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 ETS87656.1 - 1.2e-07 31.9 0.0 2e-06 28.0 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 ETS87656.1 - 9.4e-05 22.7 0.4 9.4e-05 22.7 0.4 6.2 6 1 1 7 7 7 2 Chromodomain helicase DNA-binding domain 1 SLIDE PF09111.10 ETS87656.1 - 0.0074 16.3 0.1 0.21 11.6 0.0 3.2 2 1 0 2 2 2 1 SLIDE AAA_22 PF13401.6 ETS87656.1 - 0.017 15.4 0.1 0.14 12.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain CDH1_2_SANT_HL1 PF18375.1 ETS87656.1 - 0.035 14.8 1.3 0.29 11.8 1.3 2.7 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 FF PF01846.19 ETS87657.1 - 1.9e-50 168.9 11.5 5.3e-14 52.1 0.2 7.0 6 0 0 6 6 6 6 FF domain WW PF00397.26 ETS87657.1 - 6.7e-18 64.5 15.7 9.9e-11 41.5 2.5 2.8 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 ETS87657.1 - 1.9 8.8 8.2 15 5.9 0.5 2.7 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Trs65 PF12735.7 ETS87658.1 - 8.4e-121 403.2 0.2 1.3e-120 402.6 0.2 1.3 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 E1-E2_ATPase PF00122.20 ETS87660.1 - 1e-38 132.7 10.7 2e-30 105.6 0.4 3.5 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 ETS87660.1 - 7e-28 97.6 4.6 7e-28 97.6 4.6 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ETS87660.1 - 2.1e-21 75.8 0.0 4.6e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ETS87660.1 - 3.4e-19 70.0 0.2 2.1e-14 54.3 0.0 2.8 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ETS87660.1 - 6.9e-18 64.1 0.0 5.3e-17 61.3 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ETS87660.1 - 3.7e-07 30.1 0.6 8.5e-06 25.7 0.6 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PrpF PF04303.13 ETS87661.1 - 3.6e-96 322.4 0.9 4.5e-96 322.0 0.9 1.1 1 0 0 1 1 1 1 PrpF protein Wzy_C PF04932.15 ETS87662.1 - 0.028 14.1 2.2 0.032 13.9 2.2 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF4519 PF15012.6 ETS87662.1 - 0.24 11.6 0.1 0.46 10.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Fungal_trans_2 PF11951.8 ETS87663.1 - 7.3e-20 71.1 2.1 1.8e-19 69.9 2.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Cu_amine_oxid PF01179.20 ETS87664.1 - 2.6e-152 507.5 0.0 3.3e-152 507.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 ETS87664.1 - 9e-17 61.3 0.3 2.5e-16 59.9 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 ETS87664.1 - 1.4e-14 54.1 0.0 2.6e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF4105 PF13387.6 ETS87664.1 - 0.15 11.7 0.1 0.35 10.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) Bacteriocin_II PF01721.18 ETS87664.1 - 0.16 12.1 1.0 0.53 10.4 1.0 1.9 1 0 0 1 1 1 0 Class II bacteriocin MFS_1 PF07690.16 ETS87665.1 - 5e-30 104.6 9.5 5e-30 104.6 9.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.16 ETS87665.1 - 4.1e-06 25.3 0.8 1e-05 24.0 0.3 1.8 1 1 1 2 2 2 1 BT1 family Amidohydro_3 PF07969.11 ETS87666.1 - 9.6e-75 252.8 0.5 1.2e-74 252.5 0.5 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ETS87666.1 - 1.1e-13 51.3 0.7 1.9e-09 37.3 0.2 2.9 2 1 0 2 2 2 2 Amidohydrolase family Asp PF00026.23 ETS87667.1 - 1.3e-38 133.2 0.9 2e-26 93.1 2.6 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 ETS87667.1 - 1.6e-07 31.8 1.7 2.6e-06 27.8 1.7 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ETS87667.1 - 0.028 15.0 0.1 5.8 7.6 0.1 2.8 2 1 0 2 2 2 0 Aspartyl protease Acetyltransf_3 PF13302.7 ETS87668.1 - 6.9e-34 117.5 0.0 8.1e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS87668.1 - 3.2e-07 30.6 0.0 3.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 ETS87668.1 - 5.3e-06 26.2 0.0 9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ETS87668.1 - 0.0025 17.9 0.0 0.0033 17.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GST_C_3 PF14497.6 ETS87669.1 - 6.5e-28 96.8 0.0 1.1e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ETS87669.1 - 5.6e-07 29.5 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ETS87669.1 - 0.0033 17.6 0.0 0.0056 16.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ETS87669.1 - 0.014 15.7 0.0 0.058 13.7 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Xpo1 PF08389.12 ETS87669.1 - 0.017 15.2 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 Exportin 1-like protein RRM_1 PF00076.22 ETS87670.1 - 8.9e-13 47.9 0.0 6.2e-05 22.7 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ETS87670.1 - 0.039 14.1 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif U1snRNP70_N PF12220.8 ETS87670.1 - 0.27 11.9 8.0 0.2 12.3 0.5 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CDC45 PF02724.14 ETS87670.1 - 0.84 7.8 8.3 0.65 8.2 2.3 2.0 2 0 0 2 2 2 0 CDC45-like protein DUF780 PF05611.11 ETS87670.1 - 7.1 7.5 12.1 20 6.0 12.1 1.8 1 1 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF780) DUF3405 PF11885.8 ETS87672.1 - 1.2e-224 746.8 4.4 1.4e-224 746.5 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) EMP24_GP25L PF01105.24 ETS87673.1 - 2.8e-46 157.8 0.1 3.2e-46 157.6 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Arf PF00025.21 ETS87674.1 - 9e-80 266.2 0.3 1e-79 266.0 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ETS87674.1 - 1.7e-14 54.1 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ETS87674.1 - 2e-14 53.4 0.0 2.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 ETS87674.1 - 2.4e-13 50.0 1.5 2e-09 37.1 0.5 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 ETS87674.1 - 3.4e-13 49.5 0.0 3.8e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ETS87674.1 - 1.3e-10 41.0 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ETS87674.1 - 2.9e-06 27.3 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 ETS87674.1 - 0.0096 15.2 1.1 0.029 13.7 1.1 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GCV_T PF01571.21 ETS87675.1 - 1.1e-83 280.6 0.0 1.4e-83 280.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 ETS87675.1 - 1.1e-23 83.0 0.2 2.4e-23 81.9 0.2 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF3659 PF12396.8 ETS87675.1 - 0.037 13.9 0.2 0.079 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) V-SNARE_C PF12352.8 ETS87676.1 - 9.2e-14 51.5 0.4 9.2e-14 51.5 0.4 2.9 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Not3 PF04065.15 ETS87676.1 - 0.032 13.7 2.3 0.19 11.1 0.6 2.1 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Spc7 PF08317.11 ETS87676.1 - 0.035 13.0 7.9 0.028 13.3 6.4 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein STAT_alpha PF01017.20 ETS87676.1 - 0.059 13.3 3.0 0.18 11.7 0.3 2.5 1 1 1 2 2 2 0 STAT protein, all-alpha domain FUSC PF04632.12 ETS87676.1 - 0.79 8.2 9.5 0.4 9.2 7.4 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family Ribosomal_L29 PF00831.23 ETS87677.1 - 9e-18 64.0 3.4 6e-17 61.4 0.7 2.4 2 0 0 2 2 2 2 Ribosomal L29 protein zf-H2C2_2 PF13465.6 ETS87678.1 - 3.2e-25 87.4 30.9 7.3e-08 32.5 0.4 6.7 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 ETS87678.1 - 6.6e-22 76.7 39.7 9.8e-05 22.6 1.3 7.5 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS87678.1 - 3.2e-15 55.5 42.8 0.0031 18.2 1.0 7.9 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ETS87678.1 - 5.2e-10 39.1 27.0 0.004 17.1 0.2 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf_ZIC PF18366.1 ETS87678.1 - 3.4e-06 27.0 1.3 3.4e-06 27.0 1.3 3.1 3 0 0 3 3 3 1 Zic proteins zinc finger domain zf-C2H2_jaz PF12171.8 ETS87678.1 - 0.00026 21.2 23.8 0.026 14.8 0.2 6.2 7 0 0 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ETS87678.1 - 0.0046 17.3 14.6 0.014 15.8 0.4 5.2 5 0 0 5 5 5 1 Zinc-finger of C2H2 type Arc_trans_TRASH PF08394.10 ETS87678.1 - 0.035 14.4 0.7 0.035 14.4 0.7 3.5 4 0 0 4 4 4 0 Archaeal TRASH domain BolA PF01722.18 ETS87678.1 - 0.65 10.3 6.9 2.5 8.4 0.2 3.0 3 0 0 3 3 3 0 BolA-like protein zf-C2HE PF16278.5 ETS87678.1 - 7.9 7.0 16.1 13 6.3 0.4 4.8 3 2 2 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger Pkinase PF00069.25 ETS87679.1 - 4.5e-59 200.0 0.0 1e-58 198.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS87679.1 - 1.1e-27 96.9 0.0 2.3e-27 95.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 ETS87679.1 - 1.5e-08 34.9 0.4 1.4e-07 31.8 0.3 2.4 2 0 0 2 2 2 1 FHA domain Kdo PF06293.14 ETS87679.1 - 0.051 12.9 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ETS87679.1 - 0.14 11.7 0.4 0.37 10.4 0.1 1.7 2 0 0 2 2 2 0 RIO1 family PQ-loop PF04193.14 ETS87681.1 - 2e-27 94.7 0.3 9.3e-18 63.8 0.1 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF3996 PF13161.6 ETS87681.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3996) DUF2417 PF10329.9 ETS87681.1 - 0.077 12.4 2.3 1.6 8.1 0.0 2.6 1 1 2 3 3 3 0 Region of unknown function (DUF2417) Zn_clus PF00172.18 ETS87682.1 - 0.078 13.1 14.5 0.17 12.1 14.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ppx-GppA PF02541.16 ETS87683.1 - 4.7e-35 121.4 0.0 7.5e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family O-FucT PF10250.9 ETS87684.1 - 8e-15 55.4 0.0 2.4e-14 53.8 0.0 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase CENP-B_dimeris PF09026.10 ETS87686.1 - 2.5 8.6 8.5 0.088 13.2 1.0 2.3 2 1 1 3 3 3 0 Centromere protein B dimerisation domain Oxidored_FMN PF00724.20 ETS87687.1 - 1.1e-69 235.3 0.0 1.2e-65 222.1 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_C15 PF01470.17 ETS87689.1 - 0.00098 19.3 0.1 0.012 15.8 0.1 2.0 1 1 0 1 1 1 1 Pyroglutamyl peptidase HhH-GPD PF00730.25 ETS87691.1 - 9e-05 22.9 0.0 0.00025 21.5 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Cytochrom_C1 PF02167.15 ETS87692.1 - 1.7e-93 312.4 0.0 2.1e-93 312.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 ETS87692.1 - 0.0065 16.8 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 ETS87692.1 - 0.014 16.5 0.1 0.067 14.3 0.0 2.3 3 0 0 3 3 3 0 Cytochrome c DAHP_synth_1 PF00793.20 ETS87693.1 - 5e-102 340.5 0.0 6.2e-102 340.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Transferase PF02458.15 ETS87696.1 - 1.1e-12 47.4 0.0 1.3e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Transferase family FAD_binding_3 PF01494.19 ETS87697.1 - 2.8e-21 76.2 0.1 5.8e-21 75.1 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ETS87697.1 - 0.0074 15.6 1.0 1 8.5 0.1 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS87697.1 - 0.012 15.8 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ETS87697.1 - 0.03 13.2 0.2 0.1 11.5 0.1 1.7 1 1 1 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 ETS87697.1 - 0.13 11.5 0.1 1.9 7.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Far-17a_AIG1 PF04750.14 ETS87698.1 - 4.6e-47 160.0 4.5 5.4e-47 159.7 4.5 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein p450 PF00067.22 ETS87699.1 - 2.3e-78 264.0 0.0 4.3e-78 263.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 PgaD PF13994.6 ETS87699.1 - 0.075 13.1 0.1 0.74 9.9 0.1 2.1 2 0 0 2 2 2 0 PgaD-like protein DUF3640 PF12342.8 ETS87699.1 - 0.17 11.7 0.2 0.42 10.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3640) DUF1932 PF09130.11 ETS87700.1 - 2.6e-22 78.6 1.1 5.9e-22 77.4 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 ETS87700.1 - 1e-07 32.3 0.0 1.8e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ETS87700.1 - 5e-07 30.2 0.1 1.4e-06 28.8 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 ETS87700.1 - 0.0052 16.7 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ETS87700.1 - 0.017 14.5 0.1 0.034 13.5 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YjeF_N PF03853.15 ETS87700.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus PDH PF02153.17 ETS87700.1 - 0.079 12.0 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase Sugar_tr PF00083.24 ETS87701.1 - 9.1e-32 110.5 24.7 6.6e-20 71.4 6.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ETS87701.1 - 5.8e-25 87.9 18.5 4.2e-18 65.4 11.1 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ETS87701.1 - 0.00011 20.9 20.5 0.15 10.6 4.5 3.2 3 0 0 3 3 3 3 MFS/sugar transport protein DUF2238 PF09997.9 ETS87701.1 - 5.3 6.8 8.1 8.1 6.2 0.1 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2238) Acetate_kinase PF00871.17 ETS87703.1 - 7.8e-93 311.2 0.0 9.6e-93 311.0 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family zf-C2H2 PF00096.26 ETS87704.1 - 5.8e-05 23.3 12.0 0.0024 18.2 1.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ETS87704.1 - 0.0058 17.0 2.1 0.0058 17.0 2.1 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ETS87704.1 - 0.0081 16.9 9.8 0.084 13.8 1.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Integrin_B_tail PF07965.12 ETS87704.1 - 0.025 15.0 1.8 0.033 14.7 0.5 1.8 1 1 1 2 2 2 0 Integrin beta tail domain zf-met PF12874.7 ETS87704.1 - 2.4 8.6 11.2 1.3 9.5 0.8 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Macoilin PF09726.9 ETS87704.1 - 3.6 6.0 12.3 4.4 5.7 12.3 1.1 1 0 0 1 1 1 0 Macoilin family Nop PF01798.18 ETS87705.1 - 2.2e-73 246.5 0.1 3.6e-73 245.8 0.1 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 ETS87705.1 - 3.5e-44 150.6 0.9 9.2e-44 149.2 0.9 1.8 1 0 0 1 1 1 1 Prp31 C terminal domain Sec8_exocyst PF04048.14 ETS87705.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain HAT PF02184.16 ETS87706.1 - 4.2e-23 81.0 71.1 4.4e-14 52.1 2.0 14.1 15 0 0 15 15 14 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 ETS87706.1 - 8.6e-23 79.1 35.7 0.012 16.4 0.1 11.8 8 4 5 13 13 12 8 Tetratricopeptide repeat TPR_19 PF14559.6 ETS87706.1 - 4.7e-21 75.1 2.6 2.3e-05 24.8 0.0 7.2 6 1 2 8 8 8 4 Tetratricopeptide repeat Suf PF05843.14 ETS87706.1 - 1.3e-13 51.6 21.6 0.012 15.6 0.2 7.0 3 1 4 7 7 7 4 Suppressor of forked protein (Suf) TPR_8 PF13181.6 ETS87706.1 - 9.2e-12 44.2 3.8 0.66 10.3 0.0 8.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 ETS87706.1 - 5.5e-11 42.1 5.1 0.021 15.2 0.0 6.5 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 ETS87706.1 - 2.8e-10 39.5 18.1 0.55 10.5 0.1 10.1 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_15 PF13429.6 ETS87706.1 - 1.7e-06 27.4 17.0 0.7 9.1 1.4 6.4 2 1 5 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.6 ETS87706.1 - 5.1e-06 26.8 23.3 2.4 9.0 0.2 8.5 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 ETS87706.1 - 1.2e-05 25.5 17.9 1.3 9.4 0.1 7.9 7 2 1 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 ETS87706.1 - 9.8e-05 22.9 10.7 1.8 9.3 0.5 7.5 9 1 2 11 11 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 ETS87706.1 - 0.0002 21.5 8.5 5.1 7.3 0.0 6.1 5 1 0 6 6 6 1 Tetratricopeptide repeat ECSIT PF06239.11 ETS87706.1 - 0.0062 15.7 1.4 0.046 12.8 0.1 2.6 3 0 0 3 3 3 1 Evolutionarily conserved signalling intermediate in Toll pathway Fis1_TPR_C PF14853.6 ETS87706.1 - 0.07 13.2 6.5 12 6.1 0.1 5.8 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat U3_assoc_6 PF08640.11 ETS87706.1 - 0.071 13.2 20.5 0.096 12.8 3.0 5.7 5 2 2 7 7 6 0 U3 small nucleolar RNA-associated protein 6 TPR_1 PF00515.28 ETS87706.1 - 0.89 9.5 10.5 30 4.7 0.3 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 ETS87706.1 - 3.1 8.0 18.9 30 4.9 0.1 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.10 ETS87706.1 - 8.3 6.7 7.8 3.9 7.8 0.1 4.1 4 1 1 5 5 5 0 c-SKI Smad4 binding domain WD40 PF00400.32 ETS87708.1 - 2.7e-22 78.6 4.1 4.1e-05 24.3 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS87708.1 - 2.2e-13 50.3 0.0 0.064 13.6 0.0 6.0 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ETS87708.1 - 0.0002 21.3 1.6 2.1 8.2 0.0 3.5 2 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ETS87708.1 - 0.00026 20.0 0.0 0.38 9.7 0.0 3.1 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ETS87708.1 - 0.0027 16.4 1.3 0.82 8.2 0.0 2.2 1 1 0 2 2 2 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 ETS87708.1 - 0.016 14.3 0.0 2.1 7.3 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1513) RPE65 PF03055.15 ETS87708.1 - 0.044 13.0 0.0 0.051 12.8 0.0 1.1 1 0 0 1 1 1 0 Retinal pigment epithelial membrane protein RIC1 PF07064.13 ETS87709.1 - 9.6e-95 316.8 0.3 1.4e-94 316.3 0.3 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 ETS87709.1 - 0.016 15.5 0.0 5.6 7.3 0.0 4.0 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ETS87709.1 - 0.12 13.3 2.9 36 5.5 0.1 4.9 5 0 0 5 5 5 0 WD domain, G-beta repeat PD40 PF07676.12 ETS87709.1 - 1.8 8.6 3.7 24 5.0 0.2 3.2 3 1 0 3 3 3 0 WD40-like Beta Propeller Repeat CK_II_beta PF01214.18 ETS87710.1 - 5.7e-77 257.6 0.2 7.3e-77 257.3 0.2 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit FdhE PF04216.12 ETS87710.1 - 0.045 13.6 0.0 5 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation Cwf_Cwc_15 PF04889.12 ETS87710.1 - 1.2 8.8 4.9 1.9 8.2 4.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GST_N_3 PF13417.6 ETS87711.1 - 5.7e-19 68.3 1.6 5e-17 62.1 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ETS87711.1 - 1.4e-15 57.4 1.2 5.9e-14 52.1 0.0 2.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ETS87711.1 - 1.3e-07 31.8 0.1 7.5e-07 29.4 0.0 2.4 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS87711.1 - 0.00013 21.9 0.1 0.00031 20.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ETS87711.1 - 0.018 15.6 0.0 0.034 14.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ETS87711.1 - 0.053 13.7 0.2 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF5053 PF16476.5 ETS87711.1 - 0.08 12.6 0.2 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) Glutaredoxin PF00462.24 ETS87711.1 - 0.12 12.7 0.1 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 Glutaredoxin GST_C PF00043.25 ETS87711.1 - 0.16 12.2 0.7 0.49 10.7 0.0 2.1 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain TspO_MBR PF03073.15 ETS87712.1 - 3e-46 156.8 6.4 3.6e-46 156.6 6.4 1.1 1 0 0 1 1 1 1 TspO/MBR family Mito_carr PF00153.27 ETS87713.1 - 9.5e-61 201.8 0.4 6e-21 74.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4110 PF13422.6 ETS87714.1 - 3.7e-32 110.2 1.1 3.7e-32 110.2 1.1 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.6 ETS87714.1 - 3.9e-23 81.2 11.1 8.9e-07 29.1 0.1 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 ETS87714.1 - 1.2e-20 73.2 12.5 0.00017 21.5 0.0 6.6 6 2 1 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 ETS87714.1 - 2e-18 66.0 3.2 3.1e-07 30.2 0.1 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 ETS87714.1 - 2e-16 59.6 1.8 3.6e-05 23.9 0.1 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 ETS87714.1 - 5.8e-09 35.4 1.2 5.2e-05 22.7 0.1 4.9 5 1 0 5 5 5 1 Kelch motif Kelch_2 PF07646.15 ETS87714.1 - 7.5e-09 35.2 5.7 0.0013 18.6 0.1 5.1 5 1 0 5 5 5 2 Kelch motif Spore_III_AF PF09581.10 ETS87714.1 - 0.016 15.2 0.1 12 5.9 6.3 2.3 2 1 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Cellulose_synt PF03552.14 ETS87714.1 - 0.9 7.9 1.7 1.3 7.4 1.7 1.2 1 0 0 1 1 1 0 Cellulose synthase CDC45 PF02724.14 ETS87714.1 - 2.4 6.3 18.7 0.38 9.0 9.3 2.1 2 0 0 2 2 2 0 CDC45-like protein WLM PF08325.10 ETS87715.1 - 1.8e-27 96.6 2.0 1e-26 94.2 2.0 2.2 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 ETS87715.1 - 2.8e-07 30.8 1.7 2.8e-07 30.8 1.7 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF45 C1_2 PF03107.16 ETS87715.1 - 0.21 11.9 1.2 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 C1 domain DZR PF12773.7 ETS87715.1 - 2.4 8.2 8.5 7.1 6.7 8.5 1.8 1 0 0 1 1 1 0 Double zinc ribbon Acetyltransf_3 PF13302.7 ETS87717.1 - 1.9e-25 90.2 0.0 4.4e-25 89.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS87717.1 - 0.083 12.9 0.0 0.72 9.9 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_8 PF13523.6 ETS87717.1 - 0.15 11.7 0.3 18 5.0 0.2 2.8 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain eIF2_C PF09173.11 ETS87718.1 - 2.7e-34 117.3 0.3 6.2e-34 116.1 0.3 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 ETS87718.1 - 3.1e-22 79.1 1.8 4.1e-21 75.4 1.8 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 ETS87718.1 - 1.9e-10 41.0 0.2 4.1e-10 39.9 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ETS87718.1 - 0.0029 17.7 0.0 0.0061 16.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 ETS87718.1 - 0.0042 17.1 0.8 0.016 15.2 0.1 2.2 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 ETS87718.1 - 0.022 14.7 0.4 0.2 11.5 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase OATP PF03137.20 ETS87719.1 - 0.0053 15.1 0.7 0.0093 14.3 0.6 1.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Ninjurin PF04923.12 ETS87719.1 - 0.058 13.3 1.2 0.094 12.7 0.2 1.9 1 1 0 2 2 2 0 Ninjurin DUF1772 PF08592.11 ETS87719.1 - 1.1 9.5 6.3 2.2 8.6 6.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) MARVEL PF01284.23 ETS87719.1 - 2 8.5 12.1 2.7 8.0 11.5 1.6 1 1 0 1 1 1 0 Membrane-associating domain DUF4366 PF14283.6 ETS87720.1 - 0.15 12.1 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) ADK PF00406.22 ETS87721.1 - 6.3e-44 149.7 0.1 1.1e-43 148.9 0.1 1.4 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ETS87721.1 - 4.9e-33 114.4 0.0 8.2e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETS87721.1 - 5.1e-06 27.1 0.0 8.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 ETS87721.1 - 0.0001 22.0 0.1 0.2 11.3 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 ETS87721.1 - 0.0026 17.9 0.1 0.04 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 ETS87721.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 PCI PF01399.27 ETS87722.1 - 1.3e-11 45.0 0.3 1.1e-10 42.0 0.0 2.6 3 1 0 3 3 3 1 PCI domain eIF3m_C_helix PF18005.1 ETS87722.1 - 3.5e-08 33.0 0.5 8e-08 31.9 0.5 1.7 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix BCAS2 PF05700.11 ETS87722.1 - 0.00075 19.3 0.6 0.0014 18.4 0.6 1.4 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) CpXC PF14353.6 ETS87723.1 - 0.09 12.8 0.6 0.18 11.8 0.6 1.5 1 0 0 1 1 1 0 CpXC protein zf-C2H2 PF00096.26 ETS87723.1 - 0.4 11.2 3.1 8.3 7.1 0.5 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type RXLR PF16810.5 ETS87725.1 - 0.48 10.8 4.8 0.75 10.2 4.8 1.3 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity DEAD PF00270.29 ETS87726.1 - 2.8e-47 160.7 0.0 1.2e-46 158.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS87726.1 - 6.2e-28 97.4 0.1 2.5e-27 95.4 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS87726.1 - 0.0002 21.4 0.0 0.0012 18.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2986 PF11661.8 ETS87726.1 - 0.003 18.1 3.5 0.003 18.1 3.5 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF2986) DUF3334 PF11813.8 ETS87726.1 - 0.013 15.2 0.9 0.21 11.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3334) CMS1 PF14617.6 ETS87726.1 - 0.1 11.9 0.0 0.1 11.9 0.0 2.8 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit PRAI PF00697.22 ETS87726.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Mitoc_mL59 PF18126.1 ETS87727.1 - 5e-45 153.0 2.8 5.9e-45 152.7 2.8 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Diphthami_syn_2 PF01902.17 ETS87727.1 - 0.065 12.7 0.0 0.087 12.3 0.0 1.1 1 0 0 1 1 1 0 Diphthamide synthase zf-CSL PF05207.13 ETS87728.1 - 5.5e-16 58.0 1.0 1e-15 57.2 1.0 1.5 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 ETS87728.1 - 3.6e-11 43.0 2.7 2.9e-10 40.1 2.7 2.1 1 1 0 1 1 1 1 DnaJ domain DUF2039 PF10217.9 ETS87728.1 - 6.8 7.1 6.5 18 5.7 0.5 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2039) 14-3-3 PF00244.20 ETS87729.1 - 1.1e-106 355.4 3.3 1.3e-106 355.1 3.3 1.0 1 0 0 1 1 1 1 14-3-3 protein IATP PF04568.12 ETS87730.1 - 4.2e-26 91.3 1.5 4.5e-26 91.1 1.5 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF1003 PF06210.11 ETS87730.1 - 0.72 10.0 2.5 1.1 9.4 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Nsp1_C PF05064.13 ETS87731.1 - 1.2e-37 128.2 0.9 2.6e-37 127.2 0.9 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 ETS87731.1 - 1.9e-18 67.1 157.6 2.6e-06 28.2 30.8 7.1 2 1 4 6 6 6 3 Nucleoporin FG repeat region SLATT_fungal PF18142.1 ETS87731.1 - 0.13 12.3 5.1 1 9.3 5.1 2.7 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Laminin_II PF06009.12 ETS87731.1 - 0.23 11.5 5.3 2.1 8.3 0.3 2.3 2 0 0 2 2 2 0 Laminin Domain II HIP1_clath_bdg PF16515.5 ETS87731.1 - 0.76 10.4 5.3 14 6.3 0.2 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF948 PF06103.11 ETS87731.1 - 1.3 9.3 3.2 1.2 9.4 0.3 2.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF724 PF05266.14 ETS87731.1 - 3.7 7.3 5.2 0.62 9.9 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF5102 PF17104.5 ETS87732.1 - 5.6e-111 371.2 0.4 1.1e-110 370.2 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) ERAP1_C PF11838.8 ETS87733.1 - 9.1e-86 288.3 0.3 5.8e-85 285.6 0.1 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 ETS87733.1 - 2.6e-85 285.4 0.4 4.4e-85 284.7 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 ETS87733.1 - 8.1e-49 166.3 0.3 1.4e-48 165.5 0.3 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF5011 PF16403.5 ETS87733.1 - 0.11 12.6 0.4 0.26 11.4 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5011) Sugar_tr PF00083.24 ETS87735.1 - 4.5e-26 91.7 25.1 1.4e-24 86.8 25.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3611 PF12263.8 ETS87735.1 - 0.026 14.4 0.5 0.065 13.1 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) AP_endonuc_2 PF01261.24 ETS87736.1 - 1.3e-28 99.9 0.6 5.5e-28 97.8 0.6 1.9 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel GOLD_2 PF13897.6 ETS87736.1 - 0.35 11.4 1.8 1.1 9.7 1.8 1.9 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking CDC45 PF02724.14 ETS87736.1 - 3.4 5.9 12.8 0.33 9.2 4.4 2.1 2 0 0 2 2 2 0 CDC45-like protein Rtf2 PF04641.12 ETS87736.1 - 8.1 5.7 21.1 1.4 8.2 7.5 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger Mad3_BUB1_I PF08311.12 ETS87737.1 - 4.3e-43 146.2 0.1 7.8e-43 145.4 0.1 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 ETS87737.1 - 8.4e-11 41.9 0.0 3.4e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 ETS87737.1 - 2.7e-07 30.2 0.0 1.6e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS87737.1 - 0.0015 17.8 0.0 0.0037 16.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase XRCC4 PF06632.12 ETS87737.1 - 0.068 12.0 2.8 0.13 11.1 2.8 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Enolase_C PF00113.22 ETS87738.1 - 4.9e-154 511.9 0.1 6.3e-154 511.5 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 ETS87738.1 - 1.4e-58 196.7 0.2 2.8e-58 195.8 0.2 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 ETS87738.1 - 4.9e-05 23.0 0.0 8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 ETS87738.1 - 0.085 12.0 0.2 0.92 8.6 0.1 2.2 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus DRMBL PF07522.14 ETS87739.1 - 3.3e-33 114.1 0.0 6.2e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 ETS87739.1 - 1.3e-06 28.0 0.0 2.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain VAPB_antitox PF02697.14 ETS87739.1 - 0.95 10.3 3.6 1.2 10.0 0.6 2.5 2 0 0 2 2 2 0 Putative antitoxin CBFB_NFYA PF02045.15 ETS87740.1 - 4.6e-28 97.6 4.6 9.9e-28 96.5 4.6 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B SWIRM-assoc_2 PF16496.5 ETS87740.1 - 0.29 10.0 6.2 0.38 9.6 6.2 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal UBA2_C PF16195.5 ETS87740.1 - 3.2 8.5 16.8 0.16 12.6 10.9 1.9 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus GFO_IDH_MocA PF01408.22 ETS87741.1 - 4.6e-17 63.0 0.4 1.1e-16 61.7 0.1 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 ETS87741.1 - 0.045 14.4 0.1 0.083 13.6 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain AAA_26 PF13500.6 ETS87741.1 - 0.2 11.5 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.18 ETS87742.1 - 4e-06 26.9 13.5 8.1e-06 25.9 13.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS87742.1 - 0.0027 16.8 1.8 0.004 16.2 0.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain GFO_IDH_MocA PF01408.22 ETS87743.1 - 5.9e-20 72.3 0.0 1.1e-19 71.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 ETS87743.1 - 5.3e-06 27.1 0.0 7.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 ETS87743.1 - 0.076 13.5 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sugar_tr PF00083.24 ETS87744.1 - 6.4e-82 275.8 24.8 7.3e-82 275.6 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS87744.1 - 7.2e-31 107.4 53.7 1.3e-23 83.5 26.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS87744.1 - 0.0045 15.9 18.9 0.015 14.2 2.9 3.5 2 2 0 2 2 2 2 MFS_1 like family DUF2754 PF10953.8 ETS87744.1 - 0.035 14.3 0.5 0.19 12.0 0.5 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) Ub-Mut7C PF14451.6 ETS87745.1 - 0.28 11.0 2.0 0.26 11.2 1.0 1.5 2 0 0 2 2 2 0 Mut7-C ubiquitin FSA_C PF10479.9 ETS87746.1 - 1.8 6.6 12.7 1.9 6.5 12.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Zn_clus PF00172.18 ETS87747.1 - 1.9e-07 31.1 10.5 3.2e-07 30.3 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 ETS87748.1 - 4e-23 82.2 0.0 3e-22 79.3 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS87748.1 - 1.7e-09 37.3 0.1 0.00062 19.1 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS87748.1 - 5e-09 36.2 0.4 1.3e-05 25.0 0.3 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 ETS87748.1 - 4.1e-07 30.5 0.4 7.4e-05 23.2 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS87748.1 - 1.1e-06 28.8 0.4 3.9e-06 27.0 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ETS87748.1 - 1.7e-06 27.6 0.1 0.027 13.8 0.5 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 ETS87748.1 - 4.9e-06 25.5 0.2 0.0063 15.3 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 ETS87748.1 - 6e-05 22.3 0.8 0.00011 21.4 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ETS87748.1 - 0.00072 18.9 0.0 0.025 13.9 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ETS87748.1 - 0.0072 16.0 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 ETS87748.1 - 0.0074 15.4 0.4 0.011 14.9 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 ETS87748.1 - 0.015 14.5 0.9 0.079 12.2 0.2 2.0 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 ETS87748.1 - 0.016 14.1 0.0 0.14 11.0 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.7 ETS87748.1 - 0.018 14.4 0.2 0.029 13.7 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS87748.1 - 0.022 14.7 0.1 0.048 13.6 0.1 1.7 1 1 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 ETS87748.1 - 0.042 13.7 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ETS87748.1 - 0.089 12.1 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 ETS87748.1 - 0.17 12.4 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 ETS87748.1 - 0.25 10.9 0.0 0.42 10.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain p450 PF00067.22 ETS87749.1 - 2.1e-65 221.3 0.0 2.6e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 ETS87750.1 - 7.7e-15 54.6 2.1 1.3e-14 53.9 1.8 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain UbiA PF01040.18 ETS87751.1 - 2.4e-34 118.8 12.5 3.6e-34 118.2 12.5 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Cupin_6 PF12852.7 ETS87752.1 - 0.13 11.9 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Cupin adh_short PF00106.25 ETS87753.1 - 8.3e-25 87.4 0.3 1.3e-24 86.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS87753.1 - 9.9e-15 54.7 0.1 1.3e-14 54.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS87753.1 - 1.4e-05 25.0 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS87753.1 - 2.1e-05 24.1 0.1 9.1e-05 22.0 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ETS87753.1 - 0.0023 17.8 0.1 0.0035 17.3 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Lyase_aromatic PF00221.19 ETS87754.1 - 1.4e-150 502.0 3.7 1.7e-150 501.7 3.7 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Peroxidase_2 PF01328.17 ETS87756.1 - 8.9e-46 156.8 0.1 1.2e-45 156.4 0.1 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 F-box-like PF12937.7 ETS87757.1 - 6.3e-05 22.8 0.2 0.00012 21.9 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS87757.1 - 0.00044 20.0 0.1 0.00099 18.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain TTD PF12148.8 ETS87757.1 - 0.092 12.6 0.3 0.16 11.8 0.3 1.3 1 0 0 1 1 1 0 Tandem tudor domain within UHRF1 Clr5 PF14420.6 ETS87758.1 - 3.8e-17 62.2 1.5 7.6e-17 61.3 1.5 1.5 1 0 0 1 1 1 1 Clr5 domain UPF0158 PF03682.13 ETS87758.1 - 0.014 15.3 0.3 0.03 14.3 0.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) PS-DH PF14765.6 ETS87760.1 - 4.2e-64 216.6 0.0 6.8e-64 215.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 ETS87760.1 - 5.4e-53 180.6 1.7 9.2e-53 179.8 0.8 1.8 3 0 0 3 3 3 1 Acyl transferase domain KR PF08659.10 ETS87760.1 - 1e-52 178.7 0.1 3.1e-52 177.1 0.1 1.9 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 ETS87760.1 - 4.7e-36 123.4 0.0 1.2e-35 122.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 ETS87760.1 - 4.8e-19 68.9 0.0 1.6e-18 67.2 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 ETS87760.1 - 1.7e-17 63.9 0.0 4.3e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 ETS87760.1 - 7.5e-12 45.4 0.1 4.4e-11 42.9 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 ETS87760.1 - 2.6e-09 37.7 0.0 8.9e-09 35.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS87760.1 - 8.9e-09 35.4 0.0 1.9e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 ETS87760.1 - 1.1e-07 32.9 0.0 5.9e-07 30.6 0.0 2.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 ETS87760.1 - 2.5e-07 30.6 0.0 9.4e-07 28.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS87760.1 - 5.3e-07 30.2 0.0 3.2e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain ketoacyl-synt PF00109.26 ETS87760.1 - 2.5e-06 27.2 0.1 6.6e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ADH_N PF08240.12 ETS87760.1 - 7.4e-06 25.8 0.1 2.2e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 ETS87760.1 - 9.1e-06 25.9 0.0 3.8e-05 24.0 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 ETS87760.1 - 2.6e-05 23.8 0.1 0.0011 18.5 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS87760.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 ETS87761.1 - 1.5e-29 103.0 0.0 2.2e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 ETS87761.1 - 3.6e-21 75.3 0.0 5.1e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 ETS87761.1 - 2.5e-12 46.8 0.0 3.8e-11 42.9 0.0 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 ETS87761.1 - 6.4e-06 26.4 0.3 2.6e-05 24.5 0.3 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.24 ETS87761.1 - 6.3e-05 23.4 0.0 0.00017 22.0 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 ETS87761.1 - 0.0016 17.9 0.1 2 7.7 0.0 2.8 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ETS87761.1 - 0.0023 17.1 0.0 0.17 11.0 0.0 2.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ETS87761.1 - 0.0087 15.1 0.0 3.3 6.6 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family PRT_C PF08372.10 ETS87762.1 - 0.12 12.1 0.9 0.41 10.4 0.1 2.1 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal SPC25 PF06703.11 ETS87762.1 - 1.4 8.7 7.7 0.38 10.5 0.5 2.6 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) UPF0242 PF06785.11 ETS87762.1 - 7.1 6.7 6.3 1.8 8.6 1.3 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ank_2 PF12796.7 ETS87763.1 - 1e-57 192.6 4.7 2.2e-14 53.8 0.0 5.8 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) HET PF06985.11 ETS87763.1 - 2.4e-32 112.3 0.9 4.1e-32 111.5 0.9 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_3 PF13606.6 ETS87763.1 - 1.6e-30 101.7 4.9 0.0032 17.8 0.0 11.0 13 0 0 13 13 13 7 Ankyrin repeat Ank_4 PF13637.6 ETS87763.1 - 1.6e-25 89.1 0.2 1.3e-05 25.6 0.0 7.3 4 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS87763.1 - 1.9e-24 85.4 4.9 2.3e-09 37.3 0.0 7.9 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 ETS87763.1 - 3.3e-23 81.0 14.2 0.0065 16.9 0.0 10.1 10 1 1 11 11 11 5 Ankyrin repeat Nitro_FeMo-Co PF02579.17 ETS87763.1 - 0.0041 17.4 0.0 0.049 14.0 0.0 2.7 2 0 0 2 2 2 1 Dinitrogenase iron-molybdenum cofactor Isochorismatase PF00857.20 ETS87764.1 - 1.2e-07 32.0 0.3 2e-05 24.8 0.1 2.1 1 1 1 2 2 2 2 Isochorismatase family CelTOS PF18659.1 ETS87764.1 - 0.0014 19.1 0.3 0.0021 18.5 0.2 1.4 1 1 0 1 1 1 1 Cell-traversal protein for ookinetes and sporozoites HET PF06985.11 ETS87765.1 - 7.1e-26 91.3 1.3 9.9e-26 90.8 0.1 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) NmrA PF05368.13 ETS87766.1 - 5.9e-21 75.1 0.0 8.1e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS87766.1 - 4.9e-08 33.1 0.0 1.8e-07 31.3 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 ETS87766.1 - 0.0017 18.8 0.0 0.0036 17.7 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ETS87766.1 - 0.0067 16.7 0.1 0.021 15.1 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 ETS87766.1 - 0.007 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_3 PF03447.16 ETS87766.1 - 0.081 13.6 0.0 0.51 11.0 0.0 2.1 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Glyoxalase PF00903.25 ETS87767.1 - 3.3e-12 46.7 0.0 5.5e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ETS87767.1 - 0.0066 17.2 0.0 0.012 16.4 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain SnoaL_3 PF13474.6 ETS87768.1 - 3.7e-07 30.4 0.0 5.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ETS87768.1 - 4.4e-05 23.8 0.0 0.00014 22.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) p450 PF00067.22 ETS87770.1 - 1.9e-62 211.5 0.0 2.2e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 ETS87771.1 - 5.7e-70 236.3 0.0 7.3e-70 235.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ETS87771.1 - 0.00011 22.7 0.1 0.0029 18.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ETS87771.1 - 0.00014 21.2 0.0 0.0099 15.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS87771.1 - 0.00016 20.5 0.0 0.0029 16.4 0.0 2.6 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.12 ETS87771.1 - 0.00032 19.9 0.1 0.2 10.7 0.0 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 ETS87771.1 - 0.0016 18.1 0.1 0.18 11.3 0.0 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 ETS87771.1 - 0.0075 15.8 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_8 PF13450.6 ETS87771.1 - 0.0088 16.3 0.0 0.026 14.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ETS87771.1 - 0.01 15.1 0.0 0.04 13.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS87771.1 - 0.02 14.1 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 ETS87771.1 - 0.034 13.5 0.1 0.24 10.7 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ETS87771.1 - 0.13 12.3 0.2 32 4.5 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 ETS87771.1 - 0.14 11.5 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ParB_C PF18064.1 ETS87771.1 - 0.15 12.3 0.5 0.92 9.7 0.0 2.5 3 0 0 3 3 3 0 Centromere-binding protein ParB C-terminal adh_short PF00106.25 ETS87772.1 - 8.6e-35 120.0 0.0 1.2e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS87772.1 - 1.4e-22 80.5 0.0 2e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS87772.1 - 0.0014 18.6 0.2 0.0037 17.2 0.0 1.7 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 ETS87772.1 - 0.055 12.5 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family p450 PF00067.22 ETS87773.1 - 0.0022 16.8 0.0 0.0024 16.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ETS87774.1 - 7.7e-42 143.6 0.0 1e-41 143.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 ETS87775.1 - 1.5e-16 60.6 0.0 2.9e-16 59.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS87775.1 - 4.7e-08 32.6 0.3 0.0055 16.0 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS87775.1 - 1.4e-07 31.5 0.4 0.0068 16.0 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ETS87775.1 - 0.00029 20.2 0.6 0.0055 16.0 0.6 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ETS87775.1 - 0.00035 21.1 0.1 0.28 11.8 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS87775.1 - 0.001 19.3 0.1 0.0028 17.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS87775.1 - 0.0025 16.9 0.3 0.022 13.8 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 ETS87775.1 - 0.0026 16.5 0.2 1.4 7.5 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 ETS87775.1 - 0.0036 16.4 0.1 0.0047 16.1 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 ETS87775.1 - 0.055 12.7 0.0 0.26 10.5 0.0 1.9 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase Fungal_trans PF04082.18 ETS87776.1 - 3.7e-18 65.5 0.4 7.7e-18 64.5 0.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain eIF3m_C_helix PF18005.1 ETS87776.1 - 0.04 13.6 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix FAA_hydrolase PF01557.18 ETS87777.1 - 9.5e-63 211.8 0.0 1.1e-62 211.5 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family AveC_like PF17198.4 ETS87778.1 - 5.8e-25 88.1 1.9 5.8e-25 88.1 1.9 2.1 2 0 0 2 2 2 1 Spirocyclase AveC-like Zip PF02535.22 ETS87778.1 - 0.02 14.1 0.3 0.037 13.2 0.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4201 PF13870.6 ETS87779.1 - 0.0003 20.6 8.9 0.00035 20.4 8.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Spc7 PF08317.11 ETS87779.1 - 0.00038 19.4 10.7 0.00043 19.3 10.7 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein EzrA PF06160.12 ETS87779.1 - 0.0066 14.7 8.9 0.0076 14.5 8.9 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF2968 PF11180.8 ETS87779.1 - 0.02 14.5 13.6 0.023 14.3 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) APG6_N PF17675.1 ETS87779.1 - 0.025 15.1 16.4 0.041 14.4 16.4 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region NPV_P10 PF05531.12 ETS87779.1 - 0.031 14.8 1.0 0.05 14.1 1.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Jnk-SapK_ap_N PF09744.9 ETS87779.1 - 0.054 13.7 12.4 0.063 13.5 12.4 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4509 PF14970.6 ETS87779.1 - 0.062 13.2 4.8 0.068 13.1 4.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) TolA_bind_tri PF16331.5 ETS87779.1 - 0.068 13.3 16.0 0.1 12.7 16.0 1.4 1 1 0 1 1 1 0 TolA binding protein trimerisation Ufd2P_core PF10408.9 ETS87779.1 - 0.075 11.6 2.6 0.079 11.5 2.6 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core ADIP PF11559.8 ETS87779.1 - 0.13 12.3 13.2 0.15 12.1 13.2 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fmp27_WPPW PF10359.9 ETS87779.1 - 0.13 11.0 6.6 0.15 10.9 6.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Latarcin PF10279.9 ETS87779.1 - 0.19 12.1 6.6 0.29 11.6 6.6 1.2 1 0 0 1 1 1 0 Latarcin precursor TMPIT PF07851.13 ETS87779.1 - 0.22 10.7 7.8 0.26 10.5 7.8 1.0 1 0 0 1 1 1 0 TMPIT-like protein HemX PF04375.14 ETS87779.1 - 0.29 10.4 9.4 0.38 10.0 9.4 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase AKAP7_RIRII_bdg PF10470.9 ETS87779.1 - 0.56 10.3 6.3 2 8.5 6.0 2.2 2 1 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein FUSC PF04632.12 ETS87779.1 - 1 7.8 2.5 1.1 7.8 2.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.9 ETS87779.1 - 1.4 7.9 9.1 1.6 7.8 9.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_GPO PF05929.11 ETS87779.1 - 1.5 8.4 8.1 1.6 8.3 8.1 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4446 PF14584.6 ETS87779.1 - 1.7 8.6 5.6 2.1 8.3 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) MCU PF04678.13 ETS87779.1 - 1.7 8.7 6.8 2.1 8.4 6.8 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter V_ATPase_I PF01496.19 ETS87779.1 - 1.7 6.4 7.1 1.7 6.4 7.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 ETS87779.1 - 2.4 8.2 13.7 2.9 8.0 13.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 ETS87779.1 - 2.7 8.7 10.1 3.5 8.3 9.1 1.7 1 1 1 2 2 2 0 Initiation control protein YabA AAA_23 PF13476.6 ETS87779.1 - 3.5 8.1 10.2 4 7.9 10.2 1.1 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.6 ETS87779.1 - 8.6 6.9 9.8 22 5.5 9.8 1.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF3632 PF12311.8 ETS87780.1 - 8.9e-22 78.4 0.0 1.4e-21 77.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Aminotran_4 PF01063.19 ETS87781.1 - 5.1e-30 105.0 0.0 6.2e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Fungal_trans PF04082.18 ETS87782.1 - 1.6e-21 76.6 0.1 2.4e-21 76.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 ETS87783.1 - 6e-30 104.4 33.2 6e-30 104.4 33.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Dioxygenase_C PF00775.21 ETS87784.1 - 4.8e-11 42.4 0.1 7.8e-11 41.7 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase 2OG-FeII_Oxy_3 PF13640.6 ETS87785.1 - 6.6e-09 36.5 0.0 1.6e-08 35.3 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CTF_NFI PF00859.18 ETS87785.1 - 0.19 11.6 0.0 0.23 11.3 0.0 1.1 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region Dioxygenase_C PF00775.21 ETS87786.1 - 2.2e-09 37.0 0.1 3.7e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_C PF00775.21 ETS87787.1 - 3.9e-11 42.7 0.1 6.1e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase Tyrosinase PF00264.20 ETS87788.1 - 7.1e-37 127.8 6.7 3e-36 125.8 6.7 1.8 1 1 0 1 1 1 1 Common central domain of tyrosinase NmrA PF05368.13 ETS87789.1 - 1.4e-26 93.5 0.0 1.7e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS87789.1 - 8.1e-09 35.6 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 ETS87789.1 - 0.0013 19.1 0.0 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 ETS87789.1 - 0.0031 17.0 0.1 0.0062 16.0 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ETS87789.1 - 0.0047 16.9 0.0 0.0095 15.9 0.0 1.5 1 0 0 1 1 1 1 KR domain PglD_N PF17836.1 ETS87789.1 - 0.14 12.8 0.0 0.28 11.8 0.0 1.5 1 0 0 1 1 1 0 PglD N-terminal domain Shikimate_DH PF01488.20 ETS87789.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Tannase PF07519.11 ETS87790.1 - 3.1e-71 240.7 0.0 3.9e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 ETS87790.1 - 0.028 14.1 0.1 0.061 13.0 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold GLEYA PF10528.9 ETS87791.1 - 5.2e-24 84.5 7.4 5.2e-24 84.5 7.4 3.9 3 1 0 3 3 3 1 GLEYA domain PA14 PF07691.12 ETS87791.1 - 2.5e-06 27.4 4.0 1.5e-05 24.8 1.0 2.7 2 0 0 2 2 2 1 PA14 domain Goodbye PF17109.5 ETS87791.1 - 0.035 14.6 0.7 0.095 13.2 0.7 1.7 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 ETS87793.1 - 9.3e-10 38.7 0.0 2.3e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS87793.1 - 1.4e-05 25.5 0.0 4.6e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS87793.1 - 2.4e-05 24.6 0.0 0.00012 22.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain Helo_like_N PF17111.5 ETS87793.1 - 0.0036 16.7 4.1 0.01 15.2 4.1 1.8 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_18 PF13238.6 ETS87793.1 - 0.013 16.0 0.0 0.064 13.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ETS87793.1 - 0.016 15.7 0.0 0.054 14.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 ETS87793.1 - 0.028 13.6 0.0 0.29 10.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 ETS87793.1 - 0.03 14.7 0.2 0.089 13.2 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_29 PF13555.6 ETS87793.1 - 0.07 12.9 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ETS87793.1 - 0.081 13.0 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 ETS87793.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain SesA PF17107.5 ETS87793.1 - 0.12 12.5 2.0 0.43 10.8 0.1 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_25 PF13481.6 ETS87793.1 - 0.13 11.8 0.2 0.76 9.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ETS87793.1 - 0.14 12.4 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 ETS87793.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 TBCC_N PF16752.5 ETS87793.1 - 0.14 12.6 2.4 0.66 10.4 0.8 2.5 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Pec_lyase_C PF00544.19 ETS87795.1 - 3.3e-09 36.7 3.3 2.3e-07 30.6 3.3 2.2 1 1 0 1 1 1 1 Pectate lyase DUF3176 PF11374.8 ETS87796.1 - 4.4e-32 110.5 2.1 4.4e-32 110.5 2.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) HET PF06985.11 ETS87797.1 - 3.5e-28 98.8 0.5 6.9e-28 97.8 0.5 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SUR7 PF06687.12 ETS87798.1 - 5.4e-22 78.5 11.2 6.6e-22 78.2 11.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 ETS87798.1 - 0.13 12.2 11.3 0.28 11.1 11.3 1.5 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Tyrosinase PF00264.20 ETS87799.1 - 6.3e-46 157.4 2.1 9.6e-46 156.8 2.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase C2 PF00168.30 ETS87801.1 - 3.7e-82 271.3 0.0 1.4e-23 83.1 0.0 5.5 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 ETS87801.1 - 0.00014 21.4 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain NT-C2 PF10358.9 ETS87801.1 - 0.14 11.9 0.1 3.9 7.2 0.0 3.0 3 0 0 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins SprT-like PF10263.9 ETS87802.1 - 0.026 14.4 0.8 0.094 12.6 0.2 2.2 2 1 0 2 2 2 0 SprT-like family Nodulin_late PF07127.11 ETS87802.1 - 0.21 12.0 1.5 0.47 10.8 1.5 1.5 1 0 0 1 1 1 0 Late nodulin protein FAD_binding_3 PF01494.19 ETS87803.1 - 1.9e-19 70.2 0.0 3.2e-19 69.4 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ETS87803.1 - 1.6e-08 34.7 0.3 3.9e-08 33.4 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS87803.1 - 1.7e-08 34.0 0.1 5e-08 32.5 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS87803.1 - 1.8e-08 34.4 4.4 4.2e-08 33.2 3.2 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS87803.1 - 1.2e-05 24.6 3.5 3.6e-05 23.0 2.3 2.0 1 1 1 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 ETS87803.1 - 1.8e-05 24.3 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ETS87803.1 - 2.2e-05 23.7 0.1 3e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 ETS87803.1 - 3.6e-05 24.3 0.1 0.0001 22.8 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS87803.1 - 0.00028 19.7 0.5 0.00043 19.1 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 ETS87803.1 - 0.0012 18.1 0.9 0.0017 17.5 0.9 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 ETS87803.1 - 0.0062 15.9 0.8 0.017 14.4 0.2 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 ETS87803.1 - 0.021 14.1 0.2 0.037 13.3 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 ETS87803.1 - 0.021 14.1 0.1 0.049 12.9 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS87803.1 - 0.036 13.3 0.1 0.085 12.1 0.1 1.6 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 ETS87803.1 - 0.043 13.7 0.5 0.076 12.9 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 ETS87803.1 - 0.069 12.7 0.2 0.2 11.2 0.1 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Fungal_trans PF04082.18 ETS87804.1 - 5e-09 35.6 0.0 1.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS87804.1 - 1.4e-05 25.1 12.6 2.6e-05 24.2 12.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_3 PF13417.6 ETS87805.1 - 1.4e-09 38.2 0.1 2.4e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ETS87805.1 - 1.7e-08 34.7 0.0 2.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ETS87805.1 - 8.8e-08 32.3 0.0 1.6e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ETS87805.1 - 3e-06 27.4 0.0 6.4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ETS87805.1 - 3.7e-06 27.0 0.0 8.7e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ETS87805.1 - 6.2e-06 26.1 0.1 4e-05 23.6 0.1 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 ETS87805.1 - 0.038 13.8 0.0 0.089 12.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3602 PF12223.8 ETS87806.1 - 7e-25 87.4 20.2 1.3e-21 76.9 5.6 2.5 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Glyco_hydro_10 PF00331.20 ETS87807.1 - 9.1e-106 353.6 0.2 1.1e-105 353.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 ATG22 PF11700.8 ETS87808.1 - 1.4e-197 657.1 9.9 1.7e-197 656.8 9.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like TRAP-gamma PF07074.12 ETS87808.1 - 0.12 11.9 0.9 0.31 10.6 0.9 1.6 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) BAH PF01426.18 ETS87809.1 - 0.00029 20.7 0.0 0.00058 19.7 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 ETS87809.1 - 0.0011 18.8 2.7 0.0011 18.8 2.7 1.7 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 ETS87809.1 - 0.0035 17.6 0.1 0.033 14.4 0.1 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-RING-like PF08746.11 ETS87809.1 - 0.036 14.4 0.8 0.086 13.2 0.8 1.5 1 0 0 1 1 1 0 RING-like domain zf-HC5HC2H_2 PF13832.6 ETS87809.1 - 0.065 13.4 0.1 0.18 11.9 0.1 1.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain PHD_2 PF13831.6 ETS87809.1 - 0.082 12.5 0.2 0.21 11.2 0.2 1.6 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 ETS87809.1 - 0.16 12.1 1.7 0.34 11.1 1.7 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain p450 PF00067.22 ETS87810.1 - 1.4e-46 159.2 0.0 1.7e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HEAT_PBS PF03130.16 ETS87810.1 - 0.15 12.8 0.2 1.3 9.9 0.0 2.4 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat DUF5552 PF17706.1 ETS87810.1 - 0.18 11.5 0.1 1.4 8.5 0.1 2.3 1 1 0 2 2 2 0 Family of unknown function (DUF5552) Bac_luciferase PF00296.20 ETS87811.1 - 6.2e-57 193.4 1.3 8.3e-57 193.0 1.3 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Arm-DNA-bind_3 PF13356.6 ETS87811.1 - 0.27 11.6 1.8 0.77 10.2 0.1 2.2 2 0 0 2 2 2 0 Arm DNA-binding domain Oxidored_FMN PF00724.20 ETS87812.1 - 2e-72 244.4 0.0 2.6e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 ETS87812.1 - 0.0055 15.9 0.0 0.24 10.5 0.0 2.2 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DUF1848 PF08902.11 ETS87812.1 - 0.027 14.2 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) TMP-TENI PF02581.17 ETS87812.1 - 0.065 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase Exotox-A_target PF09102.10 ETS87812.1 - 0.17 11.9 0.0 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 Exotoxin A, targeting Fungal_trans PF04082.18 ETS87813.1 - 5.9e-22 78.0 0.0 1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS87813.1 - 2.1e-08 34.2 9.2 3.4e-08 33.5 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_11 PF08241.12 ETS87815.1 - 1.1e-21 77.2 0.0 3.5e-21 75.6 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS87815.1 - 1.5e-19 70.5 0.0 3.6e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS87815.1 - 1.7e-17 63.6 0.0 3.1e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS87815.1 - 4.1e-14 52.8 0.0 6.7e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS87815.1 - 1.6e-13 51.2 0.0 3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS87815.1 - 9.5e-11 41.5 0.0 2.1e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 ETS87815.1 - 5.4e-09 35.7 0.0 7.7e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 ETS87815.1 - 1.8e-06 27.7 0.0 3.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 ETS87815.1 - 2.7e-05 23.8 0.0 4.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 ETS87815.1 - 5.8e-05 22.5 0.0 8.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PrmA PF06325.13 ETS87815.1 - 0.0051 16.2 0.0 0.0076 15.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 ETS87815.1 - 0.0077 15.4 0.0 0.022 13.9 0.0 1.7 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_8 PF05148.15 ETS87815.1 - 0.024 14.5 0.0 0.61 9.9 0.0 2.2 1 1 0 1 1 1 0 Hypothetical methyltransferase PCMT PF01135.19 ETS87815.1 - 0.027 14.2 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 ETS87815.1 - 0.035 14.1 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 ETS87815.1 - 0.037 13.5 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase TehB PF03848.14 ETS87815.1 - 0.059 12.8 0.0 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TehB RrnaAD PF00398.20 ETS87815.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase LPD22 PF18834.1 ETS87815.1 - 0.13 12.5 0.1 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 AlaDh_PNT_C PF01262.21 ETS87815.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain APH PF01636.23 ETS87816.1 - 7.3e-05 22.8 0.2 0.00014 21.9 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family CENP-X PF09415.10 ETS87816.1 - 0.13 12.6 2.6 0.33 11.3 2.6 1.6 1 0 0 1 1 1 0 CENP-S associating Centromere protein X DUF3716 PF12511.8 ETS87817.1 - 6.7e-18 64.5 1.7 1.2e-17 63.7 1.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Cupin_3 PF05899.12 ETS87817.1 - 0.0006 19.5 0.1 0.019 14.6 0.0 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF861) CENP-C_C PF11699.8 ETS87817.1 - 0.0022 18.1 0.0 0.0055 16.9 0.0 1.6 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 ETS87817.1 - 0.004 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Pirin_C PF05726.13 ETS87817.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Pirin C-terminal cupin domain ADH_zinc_N PF00107.26 ETS87818.1 - 1.2e-09 38.2 0.4 4.1e-09 36.5 0.4 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS87818.1 - 0.00028 20.7 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ETS87818.1 - 0.0012 18.7 0.1 0.0037 17.1 0.1 1.7 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase Eno-Rase_NADH_b PF12242.8 ETS87818.1 - 0.075 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase COesterase PF00135.28 ETS87819.1 - 1.6e-71 241.8 0.0 2e-71 241.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS87819.1 - 9.2e-05 22.4 0.2 0.00041 20.3 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF87 PF01935.17 ETS87822.1 - 0.00093 19.4 0.1 0.0061 16.7 0.1 2.0 1 1 0 1 1 1 1 Helicase HerA, central domain AAA_16 PF13191.6 ETS87822.1 - 0.016 15.6 0.2 0.68 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 ETS87822.1 - 0.032 14.5 0.1 0.3 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 ETS87822.1 - 0.038 13.3 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 ETS87822.1 - 0.061 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Cwf_Cwc_15 PF04889.12 ETS87822.1 - 1.5 8.5 8.1 2.9 7.6 8.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MFS_1 PF07690.16 ETS87823.1 - 3.2e-31 108.6 29.1 7.7e-31 107.3 29.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Tannase PF07519.11 ETS87824.1 - 2.2e-86 290.6 1.6 3.4e-86 290.0 1.6 1.3 1 1 0 1 1 1 1 Tannase and feruloyl esterase PAN_4 PF14295.6 ETS87826.1 - 0.0035 17.2 1.2 0.006 16.5 1.2 1.4 1 0 0 1 1 1 1 PAN domain B277 PF17623.2 ETS87826.1 - 0.0073 15.4 3.5 0.011 14.8 3.5 1.3 1 0 0 1 1 1 1 Domain of unknown function PAN_3 PF08277.12 ETS87826.1 - 0.023 14.5 1.0 0.052 13.4 1.0 1.6 1 0 0 1 1 1 0 PAN-like domain FtsX PF02687.21 ETS87826.1 - 0.072 13.6 0.7 0.12 12.9 0.7 1.3 1 0 0 1 1 1 0 FtsX-like permease family PAN_1 PF00024.26 ETS87826.1 - 0.078 12.9 1.5 0.087 12.8 0.1 1.7 2 0 0 2 2 2 0 PAN domain DUF508 PF04370.12 ETS87826.1 - 0.36 10.5 2.9 0.54 10.0 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Tic110 PF16940.5 ETS87826.1 - 1 7.8 3.0 1.3 7.5 3.0 1.0 1 0 0 1 1 1 0 Chloroplast envelope transporter CtnDOT_TraJ PF07863.11 ETS87826.1 - 1.6 9.4 6.2 6.5 7.5 0.1 2.3 2 0 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon Sporozoite_P67 PF05642.11 ETS87826.1 - 6.2 4.8 11.2 8 4.4 11.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FSA_C PF10479.9 ETS87826.1 - 7.2 4.6 8.4 7.8 4.5 8.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Adeno_PV PF03910.13 ETS87826.1 - 8.3 5.0 6.8 1.7 7.3 3.6 1.4 2 0 0 2 2 2 0 Adenovirus minor core protein PV FAD_binding_3 PF01494.19 ETS87827.1 - 4e-77 259.8 0.0 5e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ETS87827.1 - 1.1e-05 24.8 0.1 0.0015 17.8 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ETS87827.1 - 2.2e-05 24.6 0.0 5.8e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ETS87827.1 - 0.00013 21.4 0.0 0.037 13.4 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ETS87827.1 - 0.0021 17.2 0.2 0.056 12.5 0.1 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ETS87827.1 - 0.0027 17.0 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS87827.1 - 0.0028 16.9 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 ETS87827.1 - 0.0029 16.4 0.1 0.0058 15.4 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 ETS87827.1 - 0.0031 18.0 0.0 0.014 15.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ETS87827.1 - 0.0033 17.1 0.0 0.016 14.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ETS87827.1 - 0.015 14.4 0.0 0.053 12.6 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 ETS87827.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ADH_zinc_N PF00107.26 ETS87828.1 - 2.8e-23 82.3 0.2 5.5e-23 81.4 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ETS87828.1 - 1.2e-12 49.0 0.0 2.2e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS87828.1 - 2.3e-10 40.3 0.0 8.6e-10 38.5 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 ETS87828.1 - 0.021 14.3 0.3 0.035 13.6 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase ADH_N_2 PF16884.5 ETS87828.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase NmrA PF05368.13 ETS87828.1 - 0.16 11.5 0.3 0.24 11.0 0.3 1.3 1 0 0 1 1 1 0 NmrA-like family Fungal_trans PF04082.18 ETS87829.1 - 1.3e-13 50.6 0.3 2.3e-13 49.8 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 ETS87830.1 - 4.6e-25 88.3 18.0 4.6e-25 88.3 18.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4500 PF14937.6 ETS87830.1 - 0.084 12.9 0.1 0.25 11.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) adh_short PF00106.25 ETS87831.1 - 2.7e-38 131.4 0.0 6.3e-37 126.9 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS87831.1 - 2.2e-25 89.6 0.0 2.8e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS87831.1 - 0.012 15.5 0.0 1.2 9.1 0.0 2.3 1 1 0 1 1 1 0 KR domain Epimerase PF01370.21 ETS87831.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 ETS87831.1 - 0.065 13.0 0.1 5.7 6.8 0.0 2.8 2 1 1 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pro-kuma_activ PF09286.11 ETS87832.1 - 2.2e-29 102.6 0.4 4.5e-29 101.6 0.4 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain DUF1593 PF07632.11 ETS87833.1 - 8.2e-84 281.1 0.4 1.2e-83 280.6 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) CorA PF01544.18 ETS87834.1 - 1.3e-05 24.6 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF608 PF04685.13 ETS87834.1 - 0.091 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region DUF1654 PF07867.11 ETS87834.1 - 0.16 11.7 0.7 0.52 10.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) CHCH PF06747.13 ETS87836.1 - 2.4e-05 24.3 2.6 7e-05 22.9 2.4 1.8 1 1 1 2 2 2 1 CHCH domain MTCP1 PF08991.10 ETS87836.1 - 0.00011 22.3 0.4 0.00016 21.8 0.4 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 ETS87836.1 - 0.0029 17.9 3.4 0.0044 17.3 3.2 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 NatB_MDM20 PF09797.9 ETS87837.1 - 1.3e-38 133.0 0.1 2.1e-38 132.3 0.1 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit FERM_N_2 PF18038.1 ETS87837.1 - 0.039 14.8 0.2 0.12 13.2 0.2 2.0 1 0 0 1 1 1 0 FERM N-terminal domain Ilm1 PF10311.9 ETS87838.1 - 8e-58 194.7 0.4 9.5e-58 194.5 0.4 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 DUF3165 PF11364.8 ETS87838.1 - 0.083 13.2 3.0 0.54 10.6 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3165) Prenyltrans PF00432.21 ETS87839.1 - 5.6e-38 128.4 0.0 2e-08 33.8 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 ETS87839.1 - 0.087 11.9 0.1 11 5.0 0.0 3.1 1 1 2 3 3 3 0 Squalene-hopene cyclase C-terminal domain FMO-like PF00743.19 ETS87840.1 - 2.1e-11 42.9 0.2 1.3e-10 40.4 0.0 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ETS87840.1 - 5.8e-11 42.5 0.0 1.8e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ETS87840.1 - 1.3e-06 27.9 0.0 7.2e-05 22.1 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS87840.1 - 5e-06 26.0 0.1 3.3e-05 23.3 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ETS87840.1 - 4.8e-05 22.7 0.1 0.0017 17.6 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ETS87840.1 - 0.0016 18.4 0.0 0.097 12.7 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 ETS87840.1 - 0.0047 16.2 1.0 0.0068 15.7 0.1 1.7 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 ETS87840.1 - 0.0077 15.8 0.4 0.11 12.0 0.4 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase BRX_assoc PF16627.5 ETS87840.1 - 0.15 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Unstructured region between BRX_N and BRX domain FAD_binding_3 PF01494.19 ETS87840.1 - 0.38 9.9 1.0 0.67 9.1 1.0 1.3 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.16 ETS87841.1 - 1.9e-23 83.0 34.5 1.9e-23 83.0 34.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Bac_luciferase PF00296.20 ETS87842.1 - 3e-60 204.3 0.1 4.2e-60 203.8 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase CBF PF03914.17 ETS87842.1 - 0.15 12.1 0.0 4.1 7.4 0.0 2.3 2 0 0 2 2 2 0 CBF/Mak21 family Bac_luciferase PF00296.20 ETS87843.1 - 5e-57 193.7 0.8 6.4e-57 193.3 0.8 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase TRAPPC10 PF12584.8 ETS87844.1 - 3.6e-25 88.5 0.0 6.5e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 ETS87844.1 - 0.0068 16.0 0.4 0.011 15.3 0.4 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 IF-2B PF01008.17 ETS87845.1 - 5.1e-76 255.6 1.2 5.9e-76 255.4 1.2 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family M20_dimer PF07687.14 ETS87846.1 - 1.9e-22 79.2 0.0 8.6e-22 77.1 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 ETS87846.1 - 3e-17 63.0 2.7 9.9e-17 61.3 2.7 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 ETS87846.1 - 0.0015 18.3 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Dioxygenase_C PF00775.21 ETS87847.1 - 2.6e-09 36.8 0.8 6.4e-09 35.5 0.8 1.6 1 1 0 1 1 1 1 Dioxygenase DUF4198 PF10670.9 ETS87847.1 - 0.042 14.2 0.0 0.065 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) CXCR4_N PF12109.8 ETS87848.1 - 0.11 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 CXCR4 Chemokine receptor N terminal Lactonase PF10282.9 ETS87849.1 - 1.1e-06 28.2 0.0 0.0046 16.3 0.0 2.7 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller Me-amine-dh_H PF06433.11 ETS87849.1 - 0.043 12.7 0.0 0.28 10.0 0.0 2.0 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) YjcZ_2 PF09680.10 ETS87849.1 - 0.087 12.5 1.5 0.18 11.5 1.5 1.5 1 0 0 1 1 1 0 Family of unknown function Pkinase PF00069.25 ETS87850.1 - 5.6e-66 222.6 0.0 8e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS87850.1 - 1.7e-40 138.9 0.0 2.8e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ETS87850.1 - 3.5e-07 29.8 0.0 3.3e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ETS87850.1 - 8.4e-05 21.7 0.0 0.0002 20.4 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ETS87850.1 - 0.018 14.4 0.0 0.052 12.9 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ETS87850.1 - 0.023 14.3 0.1 0.062 12.9 0.1 1.7 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 ETS87850.1 - 0.043 13.7 2.1 0.047 13.6 0.1 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ETS87850.1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Peptidase_M28 PF04389.17 ETS87851.1 - 3.6e-37 128.0 0.0 4.5e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Sugarporin_N PF11471.8 ETS87851.1 - 0.045 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Pectate_lyase_3 PF12708.7 ETS87852.1 - 9.4e-12 45.2 0.0 9.8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Pectate lyase superfamily protein End_N_terminal PF12218.8 ETS87852.1 - 0.046 13.4 0.1 0.072 12.8 0.1 1.4 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase p450 PF00067.22 ETS87853.1 - 1.6e-66 225.0 0.0 2e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Oxidored_FMN PF00724.20 ETS87855.1 - 1.2e-37 130.0 0.0 1.5e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.16 ETS87856.1 - 1.4e-36 126.2 52.6 1.4e-36 126.2 52.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily GET2 PF08690.10 ETS87856.1 - 0.23 11.1 0.4 0.36 10.5 0.4 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Methyltransf_23 PF13489.6 ETS87857.1 - 1.7e-11 44.2 0.0 2.5e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS87857.1 - 2e-10 40.6 0.0 3.4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS87857.1 - 2.4e-08 34.6 0.0 8.4e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS87857.1 - 1.3e-06 28.9 0.0 6.3e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ETS87857.1 - 5.1e-05 22.7 0.0 8.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 ETS87857.1 - 6.3e-05 23.6 0.0 0.00012 22.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ETS87857.1 - 0.0006 19.4 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 ETS87857.1 - 0.0014 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 ETS87857.1 - 0.0075 16.4 0.0 0.0098 16.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 ETS87857.1 - 0.012 15.0 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 ETS87857.1 - 0.017 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.17 ETS87857.1 - 0.018 14.5 0.0 0.053 13.0 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.13 ETS87857.1 - 0.024 14.0 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SE PF08491.10 ETS87857.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase IDO PF01231.18 ETS87858.1 - 3.6e-13 49.1 0.2 1.6e-12 47.0 0.2 1.9 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Aldo_ket_red PF00248.21 ETS87859.1 - 2.2e-39 135.4 0.0 3.5e-39 134.7 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.22 ETS87861.1 - 3.1e-18 65.8 0.0 1.2e-10 40.8 0.1 2.1 1 1 1 2 2 2 2 Cytochrome P450 DUF3944 PF13099.6 ETS87861.1 - 0.0072 16.2 0.1 0.019 14.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3944) Amidoligase_2 PF12224.8 ETS87862.1 - 1.6e-14 54.2 0.0 1.3e-11 44.6 0.0 2.3 2 0 0 2 2 2 2 Putative amidoligase enzyme Nitroreductase PF00881.24 ETS87865.1 - 4.7e-13 49.6 0.0 5.4e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Enamelin PF15362.6 ETS87865.1 - 0.089 11.1 0.1 0.1 10.9 0.1 1.0 1 0 0 1 1 1 0 Enamelin PQ-loop PF04193.14 ETS87866.1 - 4.1e-11 42.5 18.8 6.9e-07 29.0 0.9 3.5 3 1 0 3 3 3 2 PQ loop repeat Phage_holin_3_6 PF07332.11 ETS87866.1 - 0.024 14.7 0.1 0.024 14.7 0.1 2.9 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2070 PF09843.9 ETS87866.1 - 0.33 9.2 4.3 0.51 8.6 4.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Fungal_trans PF04082.18 ETS87867.1 - 1.1e-10 41.0 0.6 1.1e-10 41.0 0.6 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain bZIP_2 PF07716.15 ETS87867.1 - 0.11 12.6 2.7 0.28 11.3 2.7 1.7 1 0 0 1 1 1 0 Basic region leucine zipper Zn_clus PF00172.18 ETS87867.1 - 0.17 12.0 6.4 0.39 10.9 6.4 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_3 PF13417.6 ETS87868.1 - 1.4e-05 25.4 0.0 4e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ETS87868.1 - 9.7e-05 22.3 0.0 0.00023 21.1 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RUN PF02759.19 ETS87868.1 - 0.066 13.2 0.1 0.12 12.3 0.0 1.4 2 0 0 2 2 2 0 RUN domain GST_C_6 PF17171.4 ETS87868.1 - 0.074 12.9 0.0 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain MBOAT_2 PF13813.6 ETS87869.1 - 1.9e-20 72.9 7.4 1.2e-19 70.3 3.9 2.7 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family adh_short PF00106.25 ETS87871.1 - 4.4e-24 85.0 0.0 1.4e-23 83.4 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS87871.1 - 1.6e-11 44.2 0.0 4.1e-10 39.6 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ETS87871.1 - 0.0058 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS87871.1 - 0.03 13.5 0.2 2.5 7.2 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 ETS87871.1 - 0.031 14.1 0.1 0.056 13.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 ETS87871.1 - 0.071 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Suc_Fer-like PF06999.12 ETS87871.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Sucrase/ferredoxin-like HET PF06985.11 ETS87873.1 - 7.7e-39 133.4 0.1 6.9e-38 130.3 0.1 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_5 PF13857.6 ETS87873.1 - 5e-07 29.9 2.1 0.00044 20.5 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ETS87873.1 - 6.3e-07 29.8 0.1 1.6e-06 28.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ETS87873.1 - 6.1e-06 26.7 0.0 1.3e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ETS87873.1 - 0.00011 22.5 0.1 0.03 14.8 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 ETS87873.1 - 0.0017 18.7 0.0 0.017 15.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Fungal_trans PF04082.18 ETS87875.1 - 1.5e-19 70.1 0.0 3.3e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS87875.1 - 2.3e-06 27.6 8.0 4.7e-06 26.6 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3573 PF12097.8 ETS87875.1 - 0.51 9.1 1.8 0.81 8.4 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) FAA_hydrolase PF01557.18 ETS87876.1 - 2.4e-56 190.8 0.0 3.3e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 ETS87876.1 - 3.1e-31 107.7 0.0 5.3e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal HgmA PF04209.13 ETS87877.1 - 4.7e-200 664.7 0.0 5.3e-200 664.5 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase AA_permease_2 PF13520.6 ETS87878.1 - 3.9e-61 207.2 45.9 5.2e-61 206.8 45.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS87878.1 - 1.6e-25 89.6 41.6 2.2e-25 89.2 41.6 1.0 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 ETS87879.1 - 8.7e-69 232.4 0.0 9.8e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pec_lyase_C PF00544.19 ETS87880.1 - 1.9e-16 60.3 12.3 1.5e-14 54.1 12.3 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 ETS87880.1 - 1e-08 35.2 14.2 2e-05 24.5 8.7 2.3 1 1 1 2 2 2 2 Right handed beta helix region NmrA PF05368.13 ETS87881.1 - 2.4e-24 86.2 2.1 2.9e-24 85.9 2.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ETS87881.1 - 1.9e-22 80.1 0.8 3.1e-22 79.3 0.8 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ETS87881.1 - 2.3e-07 30.6 0.3 6.4e-07 29.1 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ETS87881.1 - 4.9e-05 23.6 1.5 5.5e-05 23.4 0.3 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 ETS87881.1 - 0.00038 20.9 0.5 0.00038 20.9 0.5 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 ETS87881.1 - 0.0015 17.7 0.3 0.003 16.7 0.3 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.20 ETS87881.1 - 0.0074 16.4 0.3 0.0074 16.4 0.3 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 ETS87881.1 - 0.027 13.5 0.1 0.065 12.2 0.1 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TcdB_toxin_midN PF12256.8 ETS87881.1 - 0.048 13.0 0.0 0.092 12.1 0.0 1.5 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region 2-Hacid_dh_C PF02826.19 ETS87881.1 - 0.05 13.0 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 ETS87881.1 - 0.054 14.0 2.0 0.12 12.9 0.7 2.0 2 0 0 2 2 2 0 CoA binding domain Sybindin PF04099.12 ETS87881.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Sybindin-like family THF_DHG_CYH_C PF02882.19 ETS87881.1 - 0.16 11.3 2.4 0.16 11.3 0.7 2.1 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 ETS87881.1 - 0.25 11.2 3.4 0.11 12.4 0.5 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 ETS87881.1 - 0.43 10.0 3.7 0.22 11.0 0.5 2.0 2 0 0 2 2 2 0 short chain dehydrogenase Dabb PF07876.12 ETS87882.1 - 6e-14 52.4 0.1 6.8e-14 52.3 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Fimbrial_PilY2 PF14481.6 ETS87882.1 - 0.016 14.8 0.0 0.032 13.9 0.0 1.5 1 1 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 Aldedh PF00171.22 ETS87883.1 - 3.7e-159 530.1 0.0 4.2e-159 530.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ETS87883.1 - 0.089 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Rhodanese PF00581.20 ETS87885.1 - 2.2e-06 28.1 0.0 3.1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain ILEI PF15711.5 ETS87885.1 - 0.048 14.1 0.0 0.13 12.7 0.0 1.7 2 0 0 2 2 2 0 Interleukin-like EMT inducer H_lectin PF09458.10 ETS87887.1 - 2.9e-35 120.3 2.6 3.4e-12 46.4 1.4 3.8 3 0 0 3 3 3 3 H-type lectin domain DUF1829 PF08862.10 ETS87887.1 - 0.093 13.2 0.0 0.36 11.3 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function DUF1829 Tannase PF07519.11 ETS87888.1 - 1.1e-99 334.5 2.2 3.8e-99 332.7 2.3 1.7 1 1 0 1 1 1 1 Tannase and feruloyl esterase BSMAP PF12280.8 ETS87889.1 - 0.28 11.4 6.4 2.1 8.5 1.5 2.2 1 1 1 2 2 2 0 Brain specific membrane anchored protein Pro-kuma_activ PF09286.11 ETS87890.1 - 2.8e-28 99.0 0.0 4.6e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ETS87890.1 - 0.078 12.2 0.3 0.15 11.3 0.3 1.5 1 0 0 1 1 1 0 Subtilase family HET PF06985.11 ETS87891.1 - 3.2e-31 108.6 0.0 5.2e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.25 ETS87892.1 - 3.4e-19 69.1 0.0 1.4e-18 67.1 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ETS87892.1 - 1.8e-10 41.0 0.2 2.6e-10 40.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ETS87892.1 - 0.0013 18.0 0.1 0.0016 17.6 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 ETS87892.1 - 0.072 13.3 0.0 0.15 12.3 0.1 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain MFS_1 PF07690.16 ETS87893.1 - 3.2e-31 108.5 42.5 3.8e-31 108.3 42.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Aldo_ket_red PF00248.21 ETS87894.1 - 3.4e-38 131.5 0.0 3.9e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family V_ATPase_prox PF18274.1 ETS87894.1 - 0.033 14.2 0.1 3.2 7.8 0.0 2.8 3 0 0 3 3 3 0 Vacuolar ATPase Subunit I N-terminal proximal lobe p450 PF00067.22 ETS87895.1 - 1.5e-63 215.2 0.0 1.8e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 ETS87896.1 - 8.1e-58 196.2 56.2 1e-57 195.9 56.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ETS87896.1 - 1.1e-18 67.1 44.3 1.5e-18 66.7 44.3 1.1 1 0 0 1 1 1 1 Amino acid permease Hum_adeno_E3A PF05393.11 ETS87896.1 - 8.2 6.5 10.5 4.1 7.4 0.1 3.7 4 0 0 4 4 4 0 Human adenovirus early E3A glycoprotein Aminotran_3 PF00202.21 ETS87897.1 - 8.7e-111 370.4 0.0 9.9e-111 370.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aldedh PF00171.22 ETS87898.1 - 1.8e-169 564.2 0.0 2e-169 564.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 ETS87898.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family Cu_amine_oxid PF01179.20 ETS87899.1 - 3.9e-156 520.1 0.0 4.9e-156 519.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 ETS87899.1 - 1.6e-17 63.7 0.0 4e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 ETS87899.1 - 3.6e-12 46.3 0.0 6.4e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain p450 PF00067.22 ETS87900.1 - 6.3e-46 157.1 0.0 1.2e-45 156.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Polysacc_deac_1 PF01522.21 ETS87901.1 - 2.5e-21 75.8 0.0 3.2e-20 72.3 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF2334 PF10096.9 ETS87901.1 - 2.6e-10 40.3 0.1 8.6e-10 38.6 0.1 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 ETS87901.1 - 6.5e-06 25.6 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2194 PF09960.9 ETS87901.1 - 0.043 12.2 0.0 0.062 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) AAT PF03417.16 ETS87902.1 - 2.4e-27 96.1 0.0 3e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Fungal_trans_2 PF11951.8 ETS87903.1 - 4.4e-47 160.7 5.9 1.4e-46 159.0 5.9 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS87903.1 - 9.1e-07 28.9 9.2 1.8e-06 28.0 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 ETS87904.1 - 2e-71 240.8 0.0 3.3e-71 240.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS87904.1 - 6.3e-28 98.1 0.0 1e-27 97.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ETS87904.1 - 3e-08 33.2 1.2 1.6e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 ETS87904.1 - 3.6e-05 23.5 1.2 0.0087 15.7 0.0 2.9 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ETS87904.1 - 0.00039 20.6 2.0 0.00044 20.4 0.5 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ETS87904.1 - 0.02 13.9 0.1 0.029 13.4 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ETS87904.1 - 0.022 14.0 0.1 0.35 10.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ETS87904.1 - 0.058 12.6 0.1 0.49 9.6 0.1 2.1 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 ETS87904.1 - 0.075 11.7 0.4 0.21 10.2 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 ETS87904.1 - 0.44 10.5 1.7 0.93 9.5 0.2 2.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Ribonuc_L-PSP PF01042.21 ETS87905.1 - 9.1e-11 41.8 0.0 1.2e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Aldedh PF00171.22 ETS87906.1 - 5e-138 460.5 0.1 5.8e-138 460.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ETS87906.1 - 0.0019 17.3 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) ABC2_membrane PF01061.24 ETS87907.1 - 1.4e-70 237.0 64.6 9.8e-37 126.4 28.5 2.9 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 ETS87907.1 - 1.9e-36 125.6 0.0 1.4e-16 61.2 0.0 3.2 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 ETS87907.1 - 3.3e-31 107.0 0.1 3.3e-31 107.0 0.1 4.2 5 0 0 5 5 3 2 CDR ABC transporter ABC_trans_N PF14510.6 ETS87907.1 - 4.2e-17 62.5 0.0 1.2e-16 61.1 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 ETS87907.1 - 3.2e-07 30.1 0.1 3.6e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ETS87907.1 - 5.2e-06 27.0 0.1 0.061 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 ETS87907.1 - 8.1e-05 21.9 15.8 8.1e-05 21.9 15.8 2.7 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 ETS87907.1 - 0.00011 21.9 1.0 0.037 13.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 ETS87907.1 - 0.00033 20.8 0.2 0.0065 16.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ETS87907.1 - 0.00044 20.2 0.0 0.023 14.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 ETS87907.1 - 0.00052 20.6 0.0 0.0051 17.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 ETS87907.1 - 0.0008 19.3 0.3 0.81 9.4 0.1 3.4 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ETS87907.1 - 0.0046 17.2 0.2 1.3 9.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ETS87907.1 - 0.033 14.1 0.7 3.6 7.5 0.2 2.6 2 0 0 2 2 2 0 NACHT domain DUF2946 PF11162.8 ETS87907.1 - 0.037 14.7 0.3 0.23 12.2 0.3 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) AAA_23 PF13476.6 ETS87907.1 - 0.05 14.1 0.2 0.12 12.9 0.2 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ETS87907.1 - 0.062 13.4 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 ETS87907.1 - 0.089 13.2 0.2 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ETS87907.1 - 0.094 12.4 1.0 1.9 8.2 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 ETS87907.1 - 0.13 12.5 0.1 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 ETS87907.1 - 0.14 11.2 0.1 9.8 5.1 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.19 ETS87907.1 - 0.28 10.7 1.7 1.2 8.6 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3980 PF13140.6 ETS87907.1 - 6 7.4 9.0 2 8.9 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) Fungal_trans PF04082.18 ETS87908.1 - 9.8e-14 51.0 0.1 5.4e-13 48.6 0.1 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Phage_portal PF04860.12 ETS87909.1 - 0.00088 18.6 0.4 0.0013 18.0 0.4 1.2 1 0 0 1 1 1 1 Phage portal protein Flu_B_M2 PF04772.12 ETS87909.1 - 0.027 14.7 0.1 0.041 14.1 0.1 1.4 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) Peptidase_S10 PF00450.22 ETS87910.1 - 4e-71 240.6 0.1 5.2e-71 240.2 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase PNP_UDP_1 PF01048.20 ETS87911.1 - 6.1e-10 38.8 0.3 8.7e-09 35.0 0.3 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily Ank_2 PF12796.7 ETS87912.1 - 2.3e-29 101.8 1.0 2.7e-09 37.5 0.0 5.4 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ETS87912.1 - 2.4e-17 63.1 4.7 0.00023 21.6 0.0 7.5 4 2 5 9 9 9 7 Ankyrin repeats (many copies) NACHT PF05729.12 ETS87912.1 - 9.8e-15 54.9 0.0 2.2e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_3 PF13606.6 ETS87912.1 - 3.4e-14 51.5 2.5 0.81 10.5 0.0 8.5 8 1 1 9 9 7 3 Ankyrin repeat Ank_5 PF13857.6 ETS87912.1 - 1.6e-12 47.3 0.4 0.025 14.9 0.0 7.1 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 ETS87912.1 - 4.3e-08 33.2 3.8 0.081 13.4 0.1 6.4 7 0 0 7 7 7 2 Ankyrin repeat AAA_16 PF13191.6 ETS87912.1 - 4.1e-05 24.0 0.1 0.00013 22.4 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF249 PF03158.13 ETS87912.1 - 0.00024 20.8 0.0 0.091 12.5 0.0 3.8 3 0 0 3 3 3 1 Multigene family 530 protein UvrD-helicase PF00580.21 ETS87912.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain ResIII PF04851.15 ETS87912.1 - 0.034 14.1 0.0 0.089 12.8 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ETS87912.1 - 0.045 14.0 0.0 0.16 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ETS87912.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 ETS87912.1 - 0.094 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 ETS87912.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase AAA_7 PF12775.7 ETS87912.1 - 0.16 11.4 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Proteasome PF00227.26 ETS87914.1 - 3.3e-44 150.7 0.6 1.4e-30 106.2 0.0 2.7 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.9 ETS87914.1 - 1.5e-11 43.8 0.0 1.5e-11 43.8 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5633 PF18656.1 ETS87914.1 - 8.2 6.4 7.2 1.4 8.9 1.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5633) Glyco_hydro_61 PF03443.14 ETS87915.1 - 3.9e-51 173.9 0.7 7.3e-51 173.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 ETS87915.1 - 2.6e-08 33.7 7.5 2.6e-08 33.7 7.5 2.2 3 0 0 3 3 3 1 Fungal cellulose binding domain CENP-B_dimeris PF09026.10 ETS87915.1 - 0.099 13.0 4.7 0.19 12.1 4.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PPP4R2 PF09184.11 ETS87915.1 - 7.8 6.0 5.5 11 5.5 5.5 1.2 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 ETS87916.1 - 2.2e-197 657.7 17.1 3.4e-197 657.1 17.1 1.3 1 0 0 1 1 1 1 DNA polymerase phi Vmethyltransf PF01660.17 ETS87916.1 - 0.031 13.2 0.1 0.054 12.4 0.1 1.3 1 0 0 1 1 1 0 Viral methyltransferase RTP1_C1 PF10363.9 ETS87916.1 - 0.055 13.7 2.3 3 8.0 0.0 4.0 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Uteroglobin PF01099.17 ETS87916.1 - 0.08 13.3 1.5 0.33 11.3 0.0 2.9 2 1 0 2 2 2 0 Uteroglobin family FTA4 PF13093.6 ETS87916.1 - 0.11 12.3 1.5 0.41 10.5 1.5 2.0 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 AbiH PF14253.6 ETS87916.1 - 1.7 8.4 4.5 6.1 6.6 0.1 2.7 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH Rhodanese PF00581.20 ETS87917.1 - 4e-12 46.6 0.0 8.3e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain COesterase PF00135.28 ETS87918.1 - 3.2e-57 194.6 0.0 7e-57 193.4 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS87918.1 - 0.00048 20.1 0.1 0.0029 17.5 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold BTB PF00651.31 ETS87919.1 - 3.8e-06 27.1 0.0 6.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DEAD PF00270.29 ETS87920.1 - 5e-17 62.2 0.0 3.4e-16 59.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ETS87920.1 - 4.7e-08 33.4 0.0 2.5e-07 31.0 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS87920.1 - 0.00013 22.0 0.0 0.00039 20.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 ETS87920.1 - 0.038 14.6 0.0 0.12 13.0 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain zf-HC5HC2H_2 PF13832.6 ETS87921.1 - 1.4e-19 70.3 2.2 1.4e-19 70.3 2.2 4.2 4 0 0 4 4 4 2 PHD-zinc-finger like domain BAH PF01426.18 ETS87921.1 - 3.8e-17 62.3 0.1 7e-17 61.4 0.1 1.5 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 ETS87921.1 - 3.4e-15 56.1 3.7 3.4e-15 56.1 3.7 5.0 5 0 0 5 5 5 1 PHD-like zinc-binding domain PHD PF00628.29 ETS87921.1 - 9.6e-13 47.8 56.9 9.6e-08 31.8 5.7 6.1 7 0 0 7 7 7 3 PHD-finger PHD_2 PF13831.6 ETS87921.1 - 8.8e-10 38.0 3.8 8.8e-10 38.0 3.8 5.0 6 0 0 6 6 6 2 PHD-finger C1_1 PF00130.22 ETS87921.1 - 0.00032 20.5 0.9 0.00032 20.5 0.9 4.9 5 0 0 5 5 5 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 ETS87921.1 - 0.0018 18.1 36.2 0.0087 16.0 0.8 4.6 4 0 0 4 4 4 3 Prokaryotic RING finger family 1 C1_2 PF03107.16 ETS87921.1 - 0.0088 16.3 0.4 0.0088 16.3 0.4 6.2 7 0 0 7 7 7 3 C1 domain dCMP_cyt_deam_1 PF00383.23 ETS87922.1 - 1.2e-22 79.7 0.0 1.7e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ETS87922.1 - 1.3e-18 67.1 0.0 1.6e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 ETS87922.1 - 7.2e-05 22.9 2.4 0.068 13.2 2.4 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 ETS87922.1 - 0.0054 16.8 0.0 0.037 14.2 0.0 2.1 2 1 1 3 3 3 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 ETS87922.1 - 0.009 16.1 0.0 0.46 10.5 0.0 2.0 1 1 1 2 2 2 1 APOBEC2 NAD1 PF18778.1 ETS87922.1 - 0.0099 16.0 0.0 0.26 11.4 0.0 2.0 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 XOO_2897-deam PF14440.6 ETS87922.1 - 0.095 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase APOBEC_N PF08210.11 ETS87922.1 - 0.096 12.6 0.2 0.8 9.6 0.1 1.9 1 1 0 1 1 1 0 APOBEC-like N-terminal domain NAD2 PF18782.1 ETS87922.1 - 0.16 12.0 0.0 1.4 9.0 0.0 1.9 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 DUF4850 PF16142.5 ETS87925.1 - 0.079 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) HCNGP PF07818.13 ETS87926.1 - 1.4e-31 109.0 0.1 2e-31 108.5 0.1 1.2 1 0 0 1 1 1 1 HCNGP-like protein AAA PF00004.29 ETS87927.1 - 6.8e-43 146.3 0.0 1.2e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 ETS87927.1 - 8e-11 41.7 0.2 1.2e-09 37.9 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 ETS87927.1 - 3e-10 39.7 0.1 6.6e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 ETS87927.1 - 1.1e-07 32.4 0.0 6.7e-05 23.3 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 ETS87927.1 - 1.3e-06 28.7 0.0 9.2e-06 25.9 0.0 2.3 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 ETS87927.1 - 1.9e-06 27.9 0.1 3.8e-05 23.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ETS87927.1 - 7.1e-06 25.8 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ETS87927.1 - 0.0002 21.6 0.1 0.006 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 ETS87927.1 - 0.00026 20.3 0.0 0.00076 18.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 ETS87927.1 - 0.00061 20.3 0.1 0.0028 18.2 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_7 PF12775.7 ETS87927.1 - 0.0012 18.4 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 ETS87927.1 - 0.0021 17.3 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 ETS87927.1 - 0.0035 17.5 0.0 0.01 16.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 ETS87927.1 - 0.0036 16.7 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 ETS87927.1 - 0.0047 16.9 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 ETS87927.1 - 0.0049 17.2 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 ETS87927.1 - 0.0053 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 ETS87927.1 - 0.0065 16.5 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 ETS87927.1 - 0.0083 15.8 0.0 0.027 14.2 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 ETS87927.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ETS87927.1 - 0.018 14.8 0.0 0.057 13.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 ETS87927.1 - 0.021 14.6 0.5 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ETS87927.1 - 0.026 13.9 0.4 0.13 11.5 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_30 PF13604.6 ETS87927.1 - 0.033 13.9 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 ETS87927.1 - 0.034 13.8 0.0 0.093 12.4 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain NACHT PF05729.12 ETS87927.1 - 0.053 13.5 0.1 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 ETS87927.1 - 0.062 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF3209 PF11483.8 ETS87927.1 - 0.075 13.5 0.3 0.23 11.9 0.1 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF3209) AAA_28 PF13521.6 ETS87927.1 - 0.09 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ETS87927.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ETS87927.1 - 0.1 11.9 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Thymidylate_kin PF02223.17 ETS87927.1 - 0.12 12.1 0.1 3.8 7.2 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase eIF-1a PF01176.19 ETS87927.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 AAA_13 PF13166.6 ETS87927.1 - 0.12 11.0 2.3 7.2 5.1 1.5 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 ETS87927.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF4200 PF13863.6 ETS87927.1 - 1.3 9.5 6.2 0.13 12.7 1.4 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) Med9 PF07544.13 ETS87927.1 - 1.3 9.2 4.3 4.4 7.5 2.9 2.5 3 0 0 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 AAA_23 PF13476.6 ETS87927.1 - 6.5 7.2 6.7 26 5.2 0.4 2.8 2 1 0 2 2 2 0 AAA domain SIS PF01380.22 ETS87928.1 - 2.1e-60 202.3 0.1 7.2e-32 110.0 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 ETS87928.1 - 5e-18 65.6 0.0 9.9e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ETS87928.1 - 1.7e-10 40.8 0.0 4.3e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 ETS87928.1 - 0.0065 15.4 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 ETS87928.1 - 0.14 12.2 0.0 1.4 8.9 0.0 2.5 2 1 0 2 2 2 0 SIS domain Proteasome PF00227.26 ETS87929.1 - 1.9e-32 112.3 0.0 2.3e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF2981 PF11200.8 ETS87930.1 - 0.055 13.2 0.4 0.085 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) KAR9 PF08580.10 ETS87931.1 - 9e-180 599.6 0.3 9e-180 599.6 0.3 2.1 2 1 0 2 2 2 1 Yeast cortical protein KAR9 DNA_photolyase PF00875.18 ETS87931.1 - 0.024 14.6 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 DNA photolyase FlxA PF14282.6 ETS87931.1 - 0.036 14.0 0.2 0.12 12.4 0.2 1.8 1 0 0 1 1 1 0 FlxA-like protein DUF5583 PF17821.1 ETS87931.1 - 0.058 13.3 0.0 22 5.0 0.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5583) Syntaxin-6_N PF09177.11 ETS87931.1 - 0.11 13.1 5.8 3 8.4 0.1 3.7 2 1 0 3 3 3 0 Syntaxin 6, N-terminal SKA2 PF16740.5 ETS87931.1 - 0.16 11.8 0.5 3 7.7 0.0 3.0 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Prefoldin_2 PF01920.20 ETS87931.1 - 2.3 8.2 4.0 10 6.1 0.5 2.6 2 0 0 2 2 2 0 Prefoldin subunit DEAD PF00270.29 ETS87932.1 - 7.7e-20 71.4 0.0 1.7e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 ETS87932.1 - 8e-18 64.9 3.4 2.7e-17 63.2 3.4 2.0 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 ETS87932.1 - 2.5e-16 60.0 0.0 4.5e-15 56.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.10 ETS87932.1 - 2.8e-15 56.1 0.4 9.5e-15 54.4 0.4 2.0 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 ETS87932.1 - 1.2e-05 25.2 0.0 3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 HRDC domain ChaC PF04752.12 ETS87932.1 - 0.14 12.2 0.2 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 ChaC-like protein DUF2018 PF09442.10 ETS87932.1 - 0.21 12.6 2.6 0.4 11.7 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF2018) DUF1275 PF06912.11 ETS87933.1 - 7.4e-46 156.5 16.3 9.2e-46 156.2 16.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) BT1 PF03092.16 ETS87933.1 - 0.11 10.7 4.0 3 6.0 4.0 2.1 1 1 0 1 1 1 0 BT1 family SLATT_3 PF18184.1 ETS87933.1 - 0.21 11.7 4.4 11 6.1 2.4 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 MFS_1 PF07690.16 ETS87934.1 - 2.1e-26 92.7 32.8 7.1e-21 74.5 7.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.9 ETS87934.1 - 0.18 12.0 4.7 0.25 11.6 0.0 2.8 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GPI-anchored PF10342.9 ETS87935.1 - 2.7e-22 79.3 1.5 2.7e-22 79.3 1.5 3.1 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 ETS87935.1 - 7.5e-06 25.9 1.2 2.4e-05 24.2 0.3 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF4448) DUF5528 PF17666.1 ETS87935.1 - 2.9 7.8 3.8 4.4 7.3 2.9 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5528) KH_1 PF00013.29 ETS87936.1 - 6.8e-44 147.6 7.6 3.1e-18 65.3 0.7 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ETS87936.1 - 2.3e-12 46.5 4.0 0.0042 16.9 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ETS87936.1 - 4.6e-06 26.4 0.4 0.3 11.0 0.1 3.3 3 0 0 3 3 3 2 KH domain MOEP19 PF16005.5 ETS87936.1 - 0.00012 22.1 0.0 0.012 15.6 0.0 2.5 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 ETS87936.1 - 0.0015 18.6 9.9 0.34 11.0 0.3 3.4 3 0 0 3 3 3 3 NusA-like KH domain CENP-K PF11802.8 ETS87937.1 - 1.1e-10 41.6 1.2 2.6e-05 23.9 2.0 2.2 2 0 0 2 2 2 2 Centromere-associated protein K KASH_CCD PF14662.6 ETS87937.1 - 0.017 14.9 1.4 0.017 14.9 1.4 2.5 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH DMRT-like PF15791.5 ETS87937.1 - 0.052 14.0 1.5 6.1 7.3 0.0 2.5 2 0 0 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 Noc2 PF03715.13 ETS87937.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Noc2p family Peptidase_S49 PF01343.18 ETS87937.1 - 0.14 12.1 0.5 0.3 11.0 0.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 SHE3 PF17078.5 ETS87937.1 - 0.23 11.1 4.8 0.57 9.9 0.8 2.6 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Prefoldin_2 PF01920.20 ETS87937.1 - 0.62 10.1 12.2 2.5 8.1 1.6 3.6 3 0 0 3 3 3 0 Prefoldin subunit MAT1 PF06391.13 ETS87937.1 - 1.3 8.8 10.4 1.9 8.3 2.7 2.4 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF445 PF04286.12 ETS87937.1 - 1.8 8.3 8.6 1.5 8.6 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF445) dUTPase PF00692.19 ETS87938.1 - 6.2e-44 148.8 0.0 8.8e-44 148.3 0.0 1.2 1 0 0 1 1 1 1 dUTPase SSP160 PF06933.11 ETS87938.1 - 2.5 6.2 13.2 3.5 5.7 13.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SOG2 PF10428.9 ETS87938.1 - 2.5 7.2 10.2 3.1 6.9 10.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein FSA_C PF10479.9 ETS87938.1 - 3.8 5.5 8.7 4.8 5.2 8.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Phos_pyr_kin PF08543.12 ETS87939.1 - 2.1e-10 40.4 0.0 3.2e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 ETS87939.1 - 2.4e-06 27.1 0.9 8.7e-06 25.3 0.0 2.2 2 1 1 3 3 3 1 pfkB family carbohydrate kinase PCNA_N PF00705.18 ETS87940.1 - 6.6e-53 177.8 7.0 8.3e-53 177.5 4.7 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 ETS87940.1 - 1.1e-51 174.3 0.1 4.4e-51 172.4 0.0 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 ETS87940.1 - 1.3e-09 37.8 0.1 1.5e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 ETS87940.1 - 1.2e-07 31.1 0.9 4.2e-06 26.0 0.9 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 ETS87940.1 - 5.6e-05 22.4 0.3 0.00044 19.5 0.1 2.1 1 1 1 2 2 2 1 Hus1-like protein DNA_pol3_beta_3 PF02768.15 ETS87940.1 - 0.045 13.6 0.7 0.18 11.7 0.1 2.2 2 1 0 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain Vezatin PF12632.7 ETS87941.1 - 9.2e-31 107.2 5.2 1.4e-30 106.7 5.2 1.2 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes SAP PF02037.27 ETS87941.1 - 0.18 11.6 0.6 5.4 6.9 0.0 3.2 3 0 0 3 3 3 0 SAP domain ApoLp-III PF07464.11 ETS87941.1 - 0.39 10.8 3.0 1.5 8.9 0.1 2.9 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Rab5ip PF07019.12 ETS87942.1 - 1.1e-28 99.6 8.7 1.3e-28 99.3 8.7 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) PspC PF04024.12 ETS87942.1 - 0.12 12.2 4.4 1.4 8.8 0.0 2.4 2 1 0 2 2 2 0 PspC domain GTP_EFTU PF00009.27 ETS87943.1 - 7.1e-08 32.2 0.0 2.2e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 ETS87943.1 - 0.016 15.7 0.1 0.039 14.5 0.1 1.7 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 ETS87943.1 - 0.029 14.2 0.4 3 7.6 0.2 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 ETS87943.1 - 0.06 12.4 0.3 0.12 11.5 0.3 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF5089 PF17002.5 ETS87944.1 - 0.19 11.6 13.0 0.018 14.9 6.8 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF5089) SMBP PF16785.5 ETS87944.1 - 3.6 7.8 7.3 5.6 7.2 0.7 2.6 2 1 0 2 2 2 0 Small metal-binding protein Complex1_LYR_2 PF13233.6 ETS87945.1 - 5e-19 68.8 0.0 6.7e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 ETS87945.1 - 8.8e-08 32.1 0.5 1.5e-07 31.3 0.1 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) HA2 PF04408.23 ETS87946.1 - 6.7e-20 71.4 1.0 1.3e-19 70.5 0.0 2.0 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ETS87946.1 - 4.8e-12 46.2 0.0 1.5e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 ETS87946.1 - 7.8e-11 42.2 0.0 2.3e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 ETS87946.1 - 1.7e-07 31.2 0.0 3.5e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ETS87946.1 - 0.00022 21.5 0.0 0.00055 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ETS87946.1 - 0.0018 18.6 0.0 0.0058 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ETS87946.1 - 0.005 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 ETS87946.1 - 0.0055 17.2 0.1 0.025 15.1 0.0 2.2 3 0 0 3 3 2 1 ABC transporter CENP-U PF13097.6 ETS87946.1 - 0.0068 16.4 1.7 0.019 15.0 1.7 1.7 1 0 0 1 1 1 1 CENP-A nucleosome associated complex (NAC) subunit AAA_23 PF13476.6 ETS87946.1 - 0.015 15.8 0.3 0.6 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 ETS87946.1 - 0.05 13.0 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 ETS87946.1 - 0.054 12.8 0.0 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 ETS87946.1 - 0.086 11.9 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 ETS87946.1 - 0.15 11.4 0.0 0.4 10.0 0.0 1.6 1 0 0 1 1 1 0 KaiC RecA_dep_nuc PF16786.5 ETS87946.1 - 0.16 12.2 0.1 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 Recombination enhancement, RecA-dependent nuclease Methyltransf_16 PF10294.9 ETS87947.1 - 0.013 15.2 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Lysine methyltransferase FMO-like PF00743.19 ETS87948.1 - 4.3e-10 38.6 0.0 2.6e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ETS87948.1 - 4.4e-09 36.4 0.0 1.1e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ETS87948.1 - 4.1e-05 22.9 0.0 0.017 14.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ETS87948.1 - 0.00044 19.6 0.0 0.0063 15.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ETS87948.1 - 0.0053 16.8 0.1 0.2 11.6 0.0 3.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ETS87948.1 - 0.016 14.5 0.0 0.12 11.7 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RIFIN PF02009.16 ETS87949.1 - 0.49 10.2 4.3 0.53 10.1 4.3 1.1 1 0 0 1 1 1 0 Rifin Macoilin PF09726.9 ETS87949.1 - 8.6 4.8 10.1 10 4.5 10.1 1.0 1 0 0 1 1 1 0 Macoilin family SpoIIE PF07228.12 ETS87950.1 - 6.2e-10 39.3 0.1 3.4e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 ETS87950.1 - 7.2e-09 35.6 0.8 0.0044 16.7 0.0 2.8 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.6 ETS87950.1 - 9e-07 28.7 0.1 1.9e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C Prenyltrans PF00432.21 ETS87950.1 - 0.017 14.8 0.1 0.35 10.6 0.3 2.6 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Fer2_3 PF13085.6 ETS87951.1 - 1e-33 115.6 0.0 1.6e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 ETS87951.1 - 1.8e-08 34.8 5.5 1.8e-08 34.8 5.5 2.3 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 ETS87951.1 - 2.1e-07 31.0 2.7 2.1e-07 31.0 2.7 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 ETS87951.1 - 2.3e-07 31.1 12.4 3.1e-07 30.7 8.6 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 ETS87951.1 - 0.0022 18.5 4.4 0.0022 18.5 4.4 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 ETS87951.1 - 0.0031 17.4 0.3 0.0031 17.4 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DNA_pol3_tau_4 PF12168.8 ETS87951.1 - 0.21 12.2 1.3 0.5 11.0 0.2 2.0 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_9 PF13187.6 ETS87951.1 - 0.32 11.2 10.6 1.9 8.7 8.6 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain Torus PF16131.5 ETS87952.1 - 0.0024 18.6 2.5 0.0024 18.6 2.5 2.3 3 0 0 3 3 3 1 Torus domain zf-CCCH PF00642.24 ETS87952.1 - 0.03 14.3 7.4 0.054 13.4 7.4 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ETS87952.1 - 0.56 10.3 11.7 1 9.5 11.7 1.4 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_4 PF18044.1 ETS87952.1 - 5.4 6.9 9.3 9.9 6.1 9.3 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger CAP_GLY PF01302.25 ETS87953.1 - 2e-20 72.6 0.1 6.2e-20 71.0 0.1 1.8 2 0 0 2 2 2 1 CAP-Gly domain LRR_8 PF13855.6 ETS87953.1 - 9.4e-10 38.1 6.7 0.011 15.5 0.8 4.2 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 ETS87953.1 - 2.3e-07 31.0 13.8 0.0011 19.3 0.0 4.5 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ETS87953.1 - 0.00023 21.0 9.4 2.3 8.5 0.0 5.9 6 0 0 6 6 6 1 Leucine Rich repeat LRR_9 PF14580.6 ETS87953.1 - 0.0025 17.4 1.0 0.32 10.5 0.0 3.5 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 ETS87953.1 - 3 8.7 9.7 22 6.1 0.0 5.8 6 1 1 7 7 7 0 Leucine Rich Repeat MaoC_dehydratas PF01575.19 ETS87954.1 - 4.1e-22 78.0 0.0 6.7e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain FMN_dh PF01070.18 ETS87956.1 - 9e-106 353.8 0.0 1.1e-105 353.5 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ETS87956.1 - 1.1e-19 70.3 0.0 2.7e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 ETS87956.1 - 1.1e-06 28.0 0.1 1.7e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 ETS87956.1 - 2.6e-05 23.4 0.3 0.00012 21.2 0.2 2.0 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 ETS87956.1 - 0.0064 15.9 0.3 0.013 15.0 0.3 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 ETS87956.1 - 0.034 13.6 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein ATP11 PF06644.11 ETS87956.1 - 0.049 13.4 0.1 0.08 12.7 0.1 1.3 1 0 0 1 1 1 0 ATP11 protein DHO_dh PF01180.21 ETS87956.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Ribul_P_3_epim PF00834.19 ETS87956.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF3712 PF12505.8 ETS87957.1 - 5.3e-20 71.9 3.1 5.3e-20 71.9 3.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) PEGA PF08308.11 ETS87957.1 - 0.067 13.1 0.2 5.6 6.9 0.0 3.2 3 0 0 3 3 3 0 PEGA domain HLH PF00010.26 ETS87958.1 - 4.3e-12 45.8 1.5 1.1e-11 44.5 1.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NRBF2 PF08961.10 ETS87958.1 - 9.5e-05 22.1 3.2 0.0002 21.1 3.2 1.5 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator DUF4776 PF16003.5 ETS87958.1 - 0.0044 16.1 2.1 0.0059 15.7 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4776) Phage_GPO PF05929.11 ETS87958.1 - 0.023 14.4 1.6 0.039 13.6 1.6 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TSC22 PF01166.18 ETS87958.1 - 0.21 11.9 2.7 1.2 9.5 0.9 2.7 2 1 1 3 3 3 0 TSC-22/dip/bun family NifQ PF04891.12 ETS87958.1 - 0.38 11.1 3.4 0.64 10.4 3.4 1.3 1 0 0 1 1 1 0 NifQ bZIP_1 PF00170.21 ETS87958.1 - 0.84 9.8 5.7 0.13 12.4 1.3 1.8 1 1 1 2 2 2 0 bZIP transcription factor ZapB PF06005.12 ETS87958.1 - 2.7 8.5 12.7 0.39 11.2 5.1 2.2 1 1 1 2 2 2 0 Cell division protein ZapB CBP4 PF07960.11 ETS87958.1 - 4.4 7.2 7.2 8.8 6.2 7.2 1.4 1 0 0 1 1 1 0 CBP4 RRM_1 PF00076.22 ETS87959.1 - 1.4e-37 127.3 0.0 4.3e-19 68.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ETS87959.1 - 0.00053 20.1 0.0 0.0073 16.4 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif RRM_Rrp7 PF17799.1 ETS87959.1 - 0.0069 16.2 0.0 3.9 7.3 0.0 3.5 2 2 2 4 4 4 2 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 ETS87959.1 - 0.024 14.7 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 ETS87959.1 - 0.2 11.3 0.0 0.66 9.6 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_1 PF00515.28 ETS87960.1 - 3.4e-23 80.5 2.3 8.4e-08 31.7 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 ETS87960.1 - 1.1e-20 72.0 7.5 6.1e-06 26.0 0.1 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 ETS87960.1 - 9.6e-15 53.5 1.0 4.5e-05 23.3 0.0 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 ETS87960.1 - 1.4e-14 54.4 7.3 6.8e-06 26.6 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 ETS87960.1 - 6.2e-14 51.4 6.0 1.1e-07 31.4 0.0 4.9 3 2 2 5 5 5 3 TPR repeat TPR_19 PF14559.6 ETS87960.1 - 2.9e-13 50.1 4.1 0.00049 20.6 0.0 4.7 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 ETS87960.1 - 1.3e-11 44.3 9.0 0.00021 21.8 0.0 6.2 5 1 2 7 7 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 ETS87960.1 - 4.5e-11 42.0 2.9 0.012 15.6 0.0 6.1 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 ETS87960.1 - 6.2e-11 41.9 1.7 0.074 13.5 0.1 5.1 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 ETS87960.1 - 2.9e-10 40.3 5.3 5.5e-06 26.6 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 ETS87960.1 - 4.9e-09 36.2 1.6 0.0014 18.7 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 ETS87960.1 - 2.4e-08 34.2 1.6 0.03 14.6 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ETS87960.1 - 7.8e-05 22.8 3.0 0.056 13.7 0.7 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ETS87960.1 - 0.00016 22.1 6.9 8.8 7.2 0.0 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_3 PF07720.12 ETS87960.1 - 0.0071 16.3 0.1 8.3 6.5 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Retrotran_gag_2 PF14223.6 ETS87960.1 - 0.045 13.4 0.0 0.78 9.4 0.0 2.5 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type TPR_10 PF13374.6 ETS87960.1 - 0.12 12.3 9.8 0.49 10.3 0.2 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF1641 PF07849.11 ETS87960.1 - 0.12 12.3 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) RNase_T PF00929.24 ETS87961.1 - 3e-08 34.4 0.0 1.1e-07 32.6 0.0 2.0 2 1 0 2 2 2 1 Exonuclease Rootletin PF15035.6 ETS87962.1 - 0.00045 20.3 48.5 0.066 13.2 12.7 3.8 3 1 1 4 4 4 3 Ciliary rootlet component, centrosome cohesion Cnn_1N PF07989.11 ETS87962.1 - 0.001 19.1 6.6 0.001 19.1 6.6 6.7 3 2 2 6 6 6 1 Centrosomin N-terminal motif 1 DUF1664 PF07889.12 ETS87962.1 - 0.0023 18.0 0.9 0.0023 18.0 0.9 5.9 1 1 2 6 6 6 2 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 ETS87962.1 - 0.0099 15.9 10.2 0.0099 15.9 10.2 5.5 3 1 0 5 5 5 2 TPR/MLP1/MLP2-like protein Trimer_CC PF08954.11 ETS87962.1 - 0.16 11.5 5.0 0.15 11.6 0.4 3.3 2 0 0 2 2 2 0 Trimerisation motif Leu_zip PF15294.6 ETS87962.1 - 0.42 10.1 47.0 0.22 11.0 15.4 4.2 1 1 2 4 4 4 0 Leucine zipper TRAF_BIRC3_bd PF16673.5 ETS87962.1 - 0.43 10.4 5.2 0.15 11.9 0.2 2.9 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain IFT57 PF10498.9 ETS87962.1 - 1.1 8.1 43.1 0.15 11.0 0.3 4.5 1 1 3 4 4 4 0 Intra-flagellar transport protein 57 Cytochrom_B562 PF07361.11 ETS87962.1 - 1.6 9.4 32.7 0.41 11.3 0.2 5.6 1 1 6 7 7 7 0 Cytochrome b562 Spc7 PF08317.11 ETS87962.1 - 1.7 7.5 53.9 0.16 10.8 4.1 3.8 1 1 3 4 4 4 0 Spc7 kinetochore protein WXG100 PF06013.12 ETS87962.1 - 1.8 8.8 23.1 9.4 6.5 1.3 7.1 5 1 2 7 7 7 0 Proteins of 100 residues with WXG DUF3584 PF12128.8 ETS87962.1 - 1.9 5.9 54.2 0.017 12.6 14.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Lectin_N PF03954.14 ETS87962.1 - 2.9 7.6 32.9 0.2 11.4 3.9 5.6 4 2 2 6 6 6 0 Hepatic lectin, N-terminal domain DUF2935 PF11155.8 ETS87962.1 - 4.8 7.5 16.3 14 6.0 3.9 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) SET PF00856.28 ETS87963.1 - 1.7e-10 41.6 0.0 3.4e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 ETS87963.1 - 1.2e-09 38.0 11.6 1.2e-09 38.0 11.6 2.0 2 0 0 2 2 2 1 MYND finger Dioxygenase_C PF00775.21 ETS87964.1 - 7.7e-05 22.2 0.1 0.00016 21.2 0.1 1.5 1 0 0 1 1 1 1 Dioxygenase Tyrosinase PF00264.20 ETS87965.1 - 2.8e-36 125.9 7.2 2.2e-35 122.9 7.2 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase Acetyltransf_1 PF00583.25 ETS87966.1 - 0.018 15.2 0.1 0.031 14.5 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS87966.1 - 0.046 13.6 0.0 0.075 13.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FolB PF02152.18 ETS87967.1 - 3.6e-17 62.9 0.0 2.5e-14 53.8 0.1 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase DUF3605 PF12239.8 ETS87968.1 - 1.6e-58 197.3 0.4 2e-58 197.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) UDPGP PF01704.18 ETS87969.1 - 1.6e-191 636.4 0.0 1.8e-191 636.2 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.6 ETS87969.1 - 0.17 10.7 2.4 1.2 7.8 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4301) ING PF12998.7 ETS87970.1 - 6.4e-18 65.2 1.2 9.5e-18 64.7 1.2 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 ETS87970.1 - 2.4e-05 24.1 9.3 2.4e-05 24.1 9.3 1.8 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 ETS87970.1 - 0.067 13.4 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Hist_deacetyl PF00850.19 ETS87971.1 - 2.5e-81 273.5 0.0 3.4e-81 273.1 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain MFS_1 PF07690.16 ETS87972.1 - 2.1e-17 63.1 12.8 2.1e-17 63.1 12.8 2.4 1 1 2 3 3 3 1 Major Facilitator Superfamily PrkA PF06798.12 ETS87972.1 - 0.12 11.9 2.0 0.2 11.3 2.0 1.2 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain SUN PF03856.13 ETS87973.1 - 2.1e-90 302.5 10.4 2.9e-90 302.0 10.4 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) AF-4 PF05110.13 ETS87973.1 - 0.12 10.4 9.4 0.15 10.1 9.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Alpha_GJ PF03229.13 ETS87973.1 - 1.1 9.9 14.9 0.48 11.0 11.7 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J FSA_C PF10479.9 ETS87973.1 - 2.4 6.2 8.6 3 5.9 8.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Glyco_hydro_16 PF00722.21 ETS87974.1 - 3.6e-11 42.8 0.0 6.8e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF4981 PF16353.5 ETS87974.1 - 0.13 12.8 0.0 9.1 6.8 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function(DUF4981) Cadherin_C_2 PF16492.5 ETS87974.1 - 0.32 11.8 0.9 2 9.3 0.0 2.7 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal zf-H2C2_2 PF13465.6 ETS87975.1 - 2.4e-11 43.5 18.9 6.1e-07 29.6 2.5 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ETS87975.1 - 3.3e-09 36.7 23.2 0.0047 17.3 7.4 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS87975.1 - 9.7e-07 29.1 20.1 0.042 14.7 6.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_9 PF16293.5 ETS87975.1 - 0.0039 17.0 3.5 1.2 9.0 0.2 3.3 2 1 1 3 3 3 1 C2H2 type zinc-finger (1 copy) Vps5 PF09325.10 ETS87975.1 - 0.0079 15.8 0.1 0.012 15.1 0.1 1.2 1 0 0 1 1 1 1 Vps5 C terminal like zf-Di19 PF05605.12 ETS87975.1 - 0.036 14.4 10.3 0.092 13.1 5.8 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 ETS87975.1 - 0.04 13.8 8.1 0.045 13.6 0.9 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C2H2_6 PF13912.6 ETS87975.1 - 0.11 12.6 0.1 0.11 12.6 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger DUF1192 PF06698.11 ETS87975.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.2 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) Zn-ribbon_8 PF09723.10 ETS87975.1 - 0.28 11.3 6.6 0.46 10.6 1.7 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-CHCC PF10276.9 ETS87975.1 - 0.41 10.7 5.6 2.6 8.2 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger domain zinc_ribbon_9 PF14369.6 ETS87975.1 - 0.67 10.3 5.1 6.5 7.1 0.1 2.8 2 1 0 2 2 2 0 zinc-ribbon GAGA PF09237.11 ETS87975.1 - 1 9.2 6.2 0.96 9.3 0.5 2.8 1 1 2 3 3 3 0 GAGA factor zf-BED PF02892.15 ETS87975.1 - 1 9.4 8.0 0.62 10.1 4.1 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.8 ETS87975.1 - 1.4 9.3 11.2 7.1 7.0 4.5 3.7 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding DZR PF12773.7 ETS87975.1 - 1.5 8.9 7.5 16 5.6 7.5 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-C2HC_2 PF13913.6 ETS87975.1 - 3.3 7.7 8.2 0.16 11.9 0.7 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zinc-ribbons_6 PF07191.12 ETS87975.1 - 6.5 6.8 5.8 32 4.6 5.8 2.1 1 1 0 1 1 1 0 zinc-ribbons Ribosomal_S19 PF00203.21 ETS87976.1 - 9.2e-33 112.0 0.2 1.3e-32 111.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SIL1 PF16782.5 ETS87978.1 - 1.6e-16 60.4 0.0 2e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 FAM70 PF14967.6 ETS87979.1 - 9.7 5.5 9.6 1.4 8.3 0.3 2.5 2 0 0 2 2 2 0 FAM70 protein Ribosomal_60s PF00428.19 ETS87980.1 - 0.19 12.4 7.0 1.6 9.4 0.4 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein NUDIX PF00293.28 ETS87981.1 - 9.9e-09 35.3 0.0 2.6e-08 34.0 0.0 1.8 1 1 1 2 2 2 1 NUDIX domain DUF4614 PF15391.6 ETS87981.1 - 0.28 11.2 3.3 0.44 10.5 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Ctr PF04145.15 ETS87982.1 - 5.7e-33 114.6 4.3 6.9e-33 114.3 4.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF4190 PF13828.6 ETS87982.1 - 0.1 12.4 1.2 0.14 11.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) TMEM208_SND2 PF05620.11 ETS87982.1 - 0.13 12.0 4.4 0.34 10.7 0.1 2.3 2 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 3-HAO PF06052.12 ETS87983.1 - 3.4e-66 221.6 0.0 3.8e-66 221.4 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 ETS87983.1 - 1.1e-06 28.2 0.1 1.7e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 ETS87983.1 - 0.00091 18.9 0.1 0.0013 18.4 0.1 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 ETS87983.1 - 0.0017 18.2 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain RecQ_Zn_bind PF16124.5 ETS87983.1 - 0.0034 18.1 0.6 0.0056 17.4 0.6 1.3 1 0 0 1 1 1 1 RecQ zinc-binding DZR PF12773.7 ETS87983.1 - 0.11 12.6 1.8 0.2 11.7 1.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon ARD PF03079.14 ETS87983.1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Cupin_4 PF08007.12 ETS87983.1 - 0.2 11.1 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Pkinase PF00069.25 ETS87984.1 - 7.1e-76 255.0 0.0 9.9e-76 254.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS87984.1 - 1.6e-36 126.0 0.0 2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 ETS87984.1 - 3.7e-18 65.6 0.3 9.7e-18 64.3 0.0 1.9 2 0 0 2 2 1 1 FHA domain Kinase-like PF14531.6 ETS87984.1 - 4.3e-10 39.4 0.0 4.9e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Yop-YscD_cpl PF16697.5 ETS87984.1 - 1.6e-08 34.7 0.0 3.6e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 ETS87984.1 - 8.4e-07 28.1 0.0 1.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ETS87984.1 - 0.0025 17.2 0.2 0.0048 16.3 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ETS87984.1 - 0.0068 15.4 0.1 0.011 14.7 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 ETS87984.1 - 0.012 14.6 0.2 0.023 13.7 0.2 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FTA2 PF13095.6 ETS87984.1 - 0.028 14.0 0.2 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 ETS87984.1 - 0.092 12.3 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF2961 PF11175.8 ETS87984.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) APH PF01636.23 ETS87984.1 - 0.15 12.0 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family ArfGap PF01412.18 ETS87985.1 - 1.2e-32 112.5 0.0 3.8e-32 110.8 0.0 2.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 ETS87985.1 - 3.7e-22 79.2 12.5 6.2e-22 78.5 12.5 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 ETS87985.1 - 1.2e-11 45.1 0.9 2.2e-11 44.2 0.2 1.9 2 0 0 2 2 2 1 PH domain TF_Zn_Ribbon PF08271.12 ETS87985.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding EMP24_GP25L PF01105.24 ETS87985.1 - 0.62 10.0 3.0 1.1 9.1 1.4 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD YlqD PF11068.8 ETS87985.1 - 2.9 8.3 5.6 21 5.5 0.2 2.8 3 0 0 3 3 3 0 YlqD protein Membr_traf_MHD PF10540.9 ETS87986.1 - 6.5e-19 68.6 0.2 8.8e-09 35.7 0.0 2.6 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 ETS87986.1 - 2.4e-17 63.1 0.0 4.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 ETS87986.1 - 1.1e-06 27.5 0.2 1.9e-06 26.7 0.2 1.3 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) Dynamin_M PF01031.20 ETS87986.1 - 0.085 12.1 0.9 11 5.1 0.0 2.3 2 0 0 2 2 2 0 Dynamin central region HAMP PF00672.25 ETS87987.1 - 3.2e-37 126.7 19.3 5.4e-08 33.1 0.0 7.5 7 0 0 7 7 6 6 HAMP domain HATPase_c PF02518.26 ETS87987.1 - 1.1e-31 109.7 0.1 3.4e-31 108.0 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ETS87987.1 - 1.2e-27 96.3 4.8 1.3e-26 93.0 0.3 3.6 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 ETS87987.1 - 3.5e-17 62.2 1.9 1.7e-16 60.0 0.4 3.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_13 PF13166.6 ETS87987.1 - 0.0015 17.3 15.0 0.044 12.4 3.5 3.3 2 1 0 3 3 3 3 AAA domain DUF3829 PF12889.7 ETS87987.1 - 0.029 13.8 11.3 0.78 9.2 0.1 4.9 4 2 1 5 5 5 0 Protein of unknown function (DUF3829) HTH_6 PF01418.17 ETS87987.1 - 0.033 14.1 0.1 29 4.7 0.0 4.4 5 0 0 5 5 5 0 Helix-turn-helix domain, rpiR family DUF948 PF06103.11 ETS87987.1 - 0.073 13.3 49.5 0.72 10.2 1.5 9.5 3 2 3 6 6 6 0 Bacterial protein of unknown function (DUF948) IL32 PF15225.6 ETS87987.1 - 0.095 13.1 0.3 15 6.1 0.0 4.4 6 0 0 6 6 5 0 Interleukin 32 GhoS PF11080.8 ETS87987.1 - 0.11 12.5 5.5 2.3 8.2 0.1 4.0 4 0 0 4 4 4 0 Endoribonuclease GhoS GLE1 PF07817.13 ETS87987.1 - 0.28 10.4 4.4 21 4.2 0.1 4.0 2 1 2 5 5 5 0 GLE1-like protein Fib_alpha PF08702.10 ETS87987.1 - 0.85 9.8 27.1 0.15 12.2 0.4 6.3 6 1 0 6 6 6 0 Fibrinogen alpha/beta chain family BORCS6 PF10157.9 ETS87987.1 - 1.3 9.2 17.0 7.3 6.8 0.1 5.6 4 2 2 7 7 7 0 BLOC-1-related complex sub-unit 6 HMG_box PF00505.19 ETS87988.1 - 4.1e-11 43.1 0.9 7.1e-11 42.4 0.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ETS87988.1 - 1.4e-09 38.4 0.9 2.3e-09 37.7 0.9 1.3 1 0 0 1 1 1 1 HMG-box domain Unstab_antitox PF09720.10 ETS87988.1 - 0.11 12.5 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Putative addiction module component Cnd2 PF05786.14 ETS87989.1 - 1.8e-294 979.3 10.7 2.4e-294 978.9 10.7 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 ETS87989.1 - 0.022 15.0 0.5 0.064 13.5 0.0 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Gag_p15 PF08723.10 ETS87989.1 - 0.13 12.4 0.2 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 Gag protein p15 Pep1_7 PF17232.2 ETS87989.1 - 0.41 11.1 2.2 1.6 9.2 2.2 2.0 1 0 0 1 1 1 0 Elicitor peptide 1-7 Na_Ca_ex PF01699.24 ETS87990.1 - 9.6e-38 129.5 36.9 3.9e-28 98.3 19.0 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein WW PF00397.26 ETS87992.1 - 1.3e-11 44.3 0.1 4e-11 42.8 0.1 1.9 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 ETS87992.1 - 0.002 17.2 0.2 0.02 13.9 0.2 2.2 1 1 0 1 1 1 1 PhoD-like phosphatase HSP20 PF00011.21 ETS87993.1 - 1.8e-10 40.9 0.1 3e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ETS87993.1 - 0.0095 15.5 0.1 0.051 13.1 0.1 2.2 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Pcc1 PF09341.10 ETS87994.1 - 2.2e-32 111.0 1.4 3.5e-32 110.4 1.4 1.3 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.6 ETS87995.1 - 3.3e-42 144.3 0.0 1.6e-39 135.6 0.0 2.9 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 ETS87995.1 - 2.4e-16 59.8 0.0 4.9e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ETS87995.1 - 7.2e-06 25.7 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase COesterase PF00135.28 ETS87996.1 - 4.1e-79 266.8 0.0 4.9e-79 266.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ETS87996.1 - 7.4e-05 22.7 0.7 0.00038 20.4 0.7 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold PET117 PF15786.5 ETS87996.1 - 0.23 11.7 0.1 0.44 10.9 0.1 1.4 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial zf-C2H2 PF00096.26 ETS87997.1 - 3.7e-13 49.1 11.2 6.5e-07 29.5 0.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS87997.1 - 7.4e-08 32.6 9.2 0.0026 18.5 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ETS87997.1 - 1.5e-05 25.2 3.2 0.0054 17.1 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ETS87997.1 - 0.00011 22.5 5.9 0.00011 22.5 5.9 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ETS87997.1 - 0.0011 19.2 4.1 0.091 13.1 1.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 ETS87997.1 - 0.27 11.1 2.2 0.69 9.9 0.2 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf_C2H2_ZHX PF18387.1 ETS87997.1 - 0.3 10.8 3.8 4.5 7.0 0.2 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 ETS87997.1 - 0.32 11.0 9.1 0.15 12.1 0.3 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger Roughex PF06020.11 ETS87997.1 - 0.5 9.4 7.9 0.79 8.8 7.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein LIM PF00412.22 ETS87997.1 - 0.57 10.4 3.9 1.2 9.4 3.9 1.5 1 0 0 1 1 1 0 LIM domain zf-C2H2_11 PF16622.5 ETS87997.1 - 0.61 9.9 5.4 16 5.4 0.0 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-trcl PF13451.6 ETS87997.1 - 0.69 9.9 3.2 1.4 8.9 0.4 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain CDC45 PF02724.14 ETS87997.1 - 0.7 8.1 7.0 0.91 7.7 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-BED PF02892.15 ETS87997.1 - 1.1 9.3 6.2 0.46 10.5 2.7 2.1 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.10 ETS87997.1 - 1.3 9.2 4.1 6.1 7.1 0.4 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_3rep PF18868.1 ETS87997.1 - 1.7 9.3 7.1 13 6.5 2.8 2.8 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Diphthami_syn_2 PF01902.17 ETS87998.1 - 2e-20 73.3 0.0 9.9e-08 31.8 0.0 4.2 4 0 0 4 4 4 3 Diphthamide synthase Ribonuc_L-PSP PF01042.21 ETS87998.1 - 2.4e-07 30.8 0.3 0.0016 18.4 0.0 4.5 4 1 0 4 4 4 2 Endoribonuclease L-PSP DUF202 PF02656.15 ETS87999.1 - 2.5e-21 75.9 1.4 2.5e-21 75.9 1.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Rax2 PF12768.7 ETS87999.1 - 0.0099 15.4 2.5 0.016 14.7 1.7 1.6 2 0 0 2 2 2 1 Cortical protein marker for cell polarity DUF3382 PF11862.8 ETS87999.1 - 0.25 11.6 5.4 0.12 12.6 2.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) DUF2970 PF11174.8 ETS87999.1 - 6.2 6.8 10.6 99 2.9 9.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2970) AAA_11 PF13086.6 ETS88000.1 - 2.9e-58 197.7 0.1 1.5e-57 195.4 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 ETS88000.1 - 9.7e-48 162.4 0.0 6.7e-47 159.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ETS88000.1 - 2.1e-11 43.9 0.0 6.7e-10 39.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ETS88000.1 - 7.7e-08 32.8 0.0 3.6e-07 30.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 ETS88000.1 - 9.9e-08 31.6 0.3 3.2e-07 29.9 0.3 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 ETS88000.1 - 8.3e-06 25.5 0.1 2.2e-05 24.1 0.1 1.9 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 ETS88000.1 - 1.4e-05 25.1 0.0 5.4e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ETS88000.1 - 0.00024 21.4 0.2 0.0023 18.2 0.2 2.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 ETS88000.1 - 0.00041 20.2 0.0 0.7 9.6 0.0 2.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 ETS88000.1 - 0.00061 19.6 0.1 0.02 14.6 0.1 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.6 ETS88000.1 - 0.0014 19.1 0.0 0.0051 17.2 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain Helicase_RecD PF05127.14 ETS88000.1 - 0.0017 18.2 0.0 0.046 13.6 0.0 2.5 1 1 0 1 1 1 1 Helicase Flavi_DEAD PF07652.14 ETS88000.1 - 0.002 18.1 0.1 0.02 14.9 0.0 2.4 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_25 PF13481.6 ETS88000.1 - 0.0025 17.4 0.3 0.12 11.9 0.0 3.1 3 1 1 4 4 4 1 AAA domain PhoH PF02562.16 ETS88000.1 - 0.0026 17.2 0.0 0.084 12.3 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.17 ETS88000.1 - 0.0039 16.9 0.0 0.016 14.9 0.0 2.0 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SSE PF00437.20 ETS88000.1 - 0.0057 15.7 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 ETS88000.1 - 0.015 15.7 0.1 0.17 12.3 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ETS88000.1 - 0.032 14.0 0.0 0.21 11.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 ETS88000.1 - 0.046 12.6 0.0 0.089 11.7 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 ETS88000.1 - 0.091 13.3 0.1 0.38 11.3 0.0 1.9 1 1 0 1 1 1 0 ABC transporter MobB PF03205.14 ETS88000.1 - 0.11 12.4 0.1 0.54 10.2 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B 4HB_MCP_1 PF12729.7 ETS88000.1 - 0.11 12.0 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction AAA_33 PF13671.6 ETS88000.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 ETS88000.1 - 0.15 12.0 0.7 2.7 7.9 0.1 2.9 2 1 1 3 3 3 0 Rad17 P-loop domain Ribosomal_L30_N PF08079.12 ETS88000.1 - 0.22 11.8 4.0 0.54 10.5 4.0 1.6 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain PCB_OB PF17092.5 ETS88000.1 - 0.71 10.6 2.5 23 5.8 0.2 3.4 2 1 1 3 3 3 0 Penicillin-binding protein OB-like domain MbeD_MobD PF04899.12 ETS88001.1 - 0.038 14.1 0.2 0.67 10.1 0.0 2.4 2 0 0 2 2 2 0 MbeD/MobD like bZIP_2 PF07716.15 ETS88001.1 - 1.2 9.3 4.3 0.6 10.2 0.8 2.2 2 0 0 2 2 2 0 Basic region leucine zipper NACHT PF05729.12 ETS88002.1 - 3.4e-08 33.6 0.0 1.5e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 ETS88002.1 - 0.0017 18.6 3.1 0.0057 16.9 0.0 3.1 3 1 1 4 4 4 1 AAA domain NB-ARC PF00931.22 ETS88002.1 - 0.031 13.5 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PGBA_C PF15437.6 ETS88002.1 - 0.31 11.4 9.3 0.73 10.2 9.3 1.6 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal AAA_16 PF13191.6 ETS88002.1 - 2.2 8.6 6.8 1.1 9.6 0.0 3.2 2 1 1 3 3 3 0 AAA ATPase domain zf-MYND PF01753.18 ETS88003.1 - 4.9e-09 36.1 17.0 4.9e-09 36.1 17.0 1.6 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 ETS88003.1 - 0.042 14.2 11.6 0.11 12.8 11.6 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Ecl1 PF12855.7 ETS88003.1 - 8.4 7.5 10.8 2.6 9.2 8.1 1.6 2 1 0 2 2 2 0 ECL1/2/3 zinc binding proteins DUF2235 PF09994.9 ETS88004.1 - 3.7e-76 256.3 0.0 4.5e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Glyco_hydro_47 PF01532.20 ETS88005.1 - 6.2e-177 589.1 0.0 7.2e-177 588.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 ETS88005.1 - 0.04 12.4 0.0 1.4 7.3 0.0 2.3 2 1 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Myosin_N PF02736.19 ETS88005.1 - 0.13 12.1 0.1 0.35 10.7 0.1 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain SHR3_chaperone PF08229.11 ETS88006.1 - 7.5e-77 256.6 0.0 8.4e-77 256.4 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF2157 PF09925.9 ETS88006.1 - 0.012 15.4 1.4 2.2 8.1 0.0 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) TMEM154 PF15102.6 ETS88007.1 - 0.002 18.1 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 ETS88007.1 - 0.0021 18.9 0.0 0.0042 17.9 0.0 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 ETS88007.1 - 0.0022 18.1 3.9 0.0041 17.2 3.9 1.4 1 0 0 1 1 1 1 Podoplanin Alpha_GJ PF03229.13 ETS88007.1 - 0.0032 18.0 14.3 0.0032 18.0 14.3 2.8 2 1 1 3 3 3 1 Alphavirus glycoprotein J Amnionless PF14828.6 ETS88007.1 - 0.012 14.4 0.1 0.022 13.6 0.1 1.4 1 0 0 1 1 1 0 Amnionless Syndecan PF01034.20 ETS88007.1 - 0.013 15.4 0.1 0.026 14.4 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain RIFIN PF02009.16 ETS88007.1 - 0.037 13.9 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Rifin Insulin_TMD PF17870.1 ETS88007.1 - 0.059 13.4 0.6 0.12 12.5 0.1 1.6 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Nitrate_red_gam PF02665.14 ETS88007.1 - 0.097 12.2 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Gram_pos_anchor PF00746.21 ETS88007.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF5305 PF17231.2 ETS88007.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Phage_HK97_TLTM PF06120.11 ETS88007.1 - 0.19 10.9 0.1 0.3 10.2 0.1 1.2 1 0 0 1 1 1 0 Tail length tape measure protein SKG6 PF08693.10 ETS88007.1 - 1.3 8.5 7.9 2.6 7.5 7.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SpoIIIAH PF12685.7 ETS88007.1 - 1.3 8.8 5.7 24 4.6 0.0 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein Fungal_trans_2 PF11951.8 ETS88008.1 - 1.7e-80 270.7 0.0 2.1e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS88008.1 - 2.3e-06 27.6 9.1 3.9e-06 26.9 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_2 PF07647.17 ETS88009.1 - 4e-08 33.3 0.0 7.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ETS88009.1 - 4.3e-05 23.9 0.0 9.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 ETS88009.1 - 4.7e-05 23.9 0.0 0.0011 19.5 0.0 2.8 2 1 0 2 2 2 1 PH domain SAM_4 PF18017.1 ETS88009.1 - 0.031 14.2 0.0 0.078 13.0 0.0 1.6 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 ETS88009.1 - 0.053 13.5 0.2 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain SAM_Ste50p PF09235.10 ETS88009.1 - 0.053 13.8 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Sod_Fe_C PF02777.18 ETS88010.1 - 2.1e-15 56.7 0.0 7.3e-07 29.3 0.0 2.7 3 0 0 3 3 3 2 Iron/manganese superoxide dismutases, C-terminal domain Zn_clus PF00172.18 ETS88011.1 - 0.00038 20.5 12.2 0.00038 20.5 12.2 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WSC PF01822.19 ETS88012.1 - 1e-19 70.4 6.8 1.5e-19 69.9 6.8 1.2 1 0 0 1 1 1 1 WSC domain AAA PF00004.29 ETS88013.1 - 9.5e-18 64.9 0.1 4e-17 62.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ETS88013.1 - 0.00013 22.4 0.2 0.00047 20.6 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ETS88013.1 - 0.00083 19.6 0.5 0.049 13.9 0.1 3.1 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 ETS88013.1 - 0.0019 17.9 0.0 0.0044 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ETS88013.1 - 0.0028 17.6 0.1 0.01 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ETS88013.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 ETS88013.1 - 0.025 15.1 0.1 0.11 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ETS88013.1 - 0.036 14.4 0.0 0.18 12.2 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 ETS88013.1 - 0.037 13.6 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DivIC PF04977.15 ETS88014.1 - 0.053 13.3 1.2 0.11 12.3 0.4 1.9 2 0 0 2 2 2 0 Septum formation initiator DUF4795 PF16043.5 ETS88014.1 - 0.35 10.5 3.9 0.68 9.5 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Cnn_1N PF07989.11 ETS88014.1 - 0.65 10.2 5.7 0.38 10.9 2.7 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Peptidase_M3 PF01432.20 ETS88015.1 - 1.7e-121 406.7 0.0 2.1e-121 406.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 ETS88015.1 - 0.044 14.1 1.1 0.11 12.9 0.3 1.9 2 0 0 2 2 2 0 Effector protein Peptidase_M50B PF13398.6 ETS88015.1 - 0.21 11.2 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like ApoO PF09769.9 ETS88016.1 - 9e-38 129.2 2.0 1.1e-37 128.9 0.0 2.1 3 0 0 3 3 3 1 Apolipoprotein O DUF3054 PF11255.8 ETS88016.1 - 0.68 10.5 3.6 3.6 8.1 0.5 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF3054) Mito_carr PF00153.27 ETS88017.1 - 1.9e-65 216.9 3.2 4.2e-21 74.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PAE PF03283.13 ETS88017.1 - 0.011 14.9 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Pectinacetylesterase Serine_protease PF18405.1 ETS88017.1 - 0.051 12.7 4.0 0.88 8.7 0.2 2.7 4 0 0 4 4 4 0 Gammaproteobacterial serine protease tRNA-synt_1b PF00579.25 ETS88019.1 - 9.8e-62 208.9 0.0 1.3e-61 208.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) IMS PF00817.20 ETS88020.1 - 1.3e-38 132.4 0.0 2.5e-38 131.4 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 ETS88020.1 - 3.6e-27 94.6 2.5 7.5e-27 93.6 2.5 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 ETS88020.1 - 7.4e-16 57.0 5.6 1.6e-05 24.2 0.0 3.8 3 0 0 3 3 3 3 Ubiquitin binding region IMS_C PF11799.8 ETS88020.1 - 7.2e-13 49.3 0.0 2e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 ETS88020.1 - 1.7e-07 31.6 0.0 7.1e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain IMS_HHH PF11798.8 ETS88020.1 - 0.0014 18.9 0.1 0.032 14.6 0.0 2.9 2 0 0 2 2 2 1 IMS family HHH motif BRCT PF00533.26 ETS88020.1 - 0.0048 17.3 0.1 0.022 15.1 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain mCpol PF18182.1 ETS88020.1 - 0.0052 17.1 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 minimal CRISPR polymerase domain MgtE_N PF03448.17 ETS88020.1 - 0.0074 16.9 3.8 4 8.1 0.0 4.5 4 0 0 4 4 4 1 MgtE intracellular N domain LIG3_BRCT PF16759.5 ETS88020.1 - 0.043 14.1 0.0 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Cdd1 PF11731.8 ETS88020.1 - 0.07 13.4 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus PTCB-BRCT PF12738.7 ETS88020.1 - 0.12 12.4 0.0 0.34 10.9 0.0 1.9 1 0 0 1 1 1 0 twin BRCT domain RED_N PF07808.13 ETS88021.1 - 5.3e-07 29.5 8.8 5.3e-07 29.5 8.8 2.7 3 1 0 3 3 3 1 RED-like protein N-terminal region Lsm_interact PF05391.11 ETS88021.1 - 0.055 13.0 1.4 0.14 11.7 0.3 2.3 2 0 0 2 2 2 0 Lsm interaction motif IU_nuc_hydro PF01156.19 ETS88022.1 - 9.7e-76 255.2 0.0 1.2e-75 255.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF4286 PF14114.6 ETS88023.1 - 1.4e-06 28.7 0.0 0.00049 20.5 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4286) EthD PF07110.11 ETS88023.1 - 0.0029 18.7 0.0 0.34 12.1 0.0 2.3 2 0 0 2 2 2 2 EthD domain Mago-bind PF09282.10 ETS88024.1 - 3.9e-14 52.2 3.3 7.4e-14 51.3 3.3 1.5 1 0 0 1 1 1 1 Mago binding DUF4407 PF14362.6 ETS88024.1 - 0.22 10.9 7.5 0.23 10.8 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 ETS88024.1 - 0.42 10.4 10.4 0.45 10.3 10.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 ETS88024.1 - 1.2 7.1 4.9 1.4 7.0 4.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nucleo_P87 PF07267.11 ETS88024.1 - 1.3 7.8 7.0 1.2 7.9 7.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Neur_chan_memb PF02932.16 ETS88024.1 - 1.9 8.5 3.1 2 8.4 3.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 ETS88024.1 - 4.1 6.1 7.7 4.8 5.8 7.7 1.1 1 0 0 1 1 1 0 Presenilin UCR_UQCRX_QCR9 PF05365.12 ETS88025.1 - 3.3e-19 68.6 0.6 3.6e-19 68.5 0.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-UBR PF02207.20 ETS88026.1 - 4.4e-19 68.4 12.2 4.4e-19 68.4 12.2 2.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 ETS88026.1 - 9.7e-06 25.3 0.0 2.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Rota_Capsid_VP6 PF00980.17 ETS88026.1 - 0.14 11.1 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Rotavirus major capsid protein VP6 CAP_N PF01213.19 ETS88026.1 - 0.4 10.1 2.1 1 8.8 2.1 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Exo_endo_phos PF03372.23 ETS88027.1 - 1.1e-14 54.6 0.4 1.8e-14 53.8 0.4 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3267 PF11667.8 ETS88027.1 - 0.086 13.1 0.2 0.16 12.2 0.2 1.4 1 0 0 1 1 1 0 Putative zincin peptidase WD40 PF00400.32 ETS88028.1 - 2.4e-51 170.6 22.7 3.3e-09 37.2 0.0 8.2 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ETS88028.1 - 3.4e-21 75.3 0.0 0.0017 18.6 0.0 6.4 2 2 4 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ETS88028.1 - 4.9e-08 32.3 0.2 0.13 11.2 0.0 5.1 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 ETS88028.1 - 5.3e-07 29.0 0.1 1.9 7.4 0.0 4.8 2 1 3 5 5 5 2 VID27 C-terminal WD40-like domain eIF2A PF08662.11 ETS88028.1 - 1.6e-06 28.1 0.0 0.018 14.9 0.0 3.2 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ETS88028.1 - 2.7e-05 23.7 0.0 0.085 12.2 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain Nucleoporin_N PF08801.11 ETS88028.1 - 0.00043 19.1 0.4 0.081 11.7 0.0 2.4 2 0 0 2 2 2 2 Nup133 N terminal like PD40 PF07676.12 ETS88028.1 - 0.0046 16.9 0.2 2.3 8.3 0.1 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 ETS88028.1 - 0.024 13.2 0.2 4.2 5.8 0.0 3.1 3 1 0 3 3 3 0 Cytochrome D1 heme domain Nup160 PF11715.8 ETS88028.1 - 0.046 12.4 21.5 0.69 8.5 0.2 5.3 3 2 1 5 5 4 0 Nucleoporin Nup120/160 Secretin_N_2 PF07655.13 ETS88028.1 - 5.2 7.7 27.6 0.28 11.8 6.7 2.9 2 0 0 2 2 2 0 Secretin N-terminal domain Apt1 PF10351.9 ETS88028.1 - 6.8 5.4 26.3 1.4 7.7 20.9 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain Pkinase PF00069.25 ETS88029.1 - 4.4e-51 173.8 0.0 1.6e-30 106.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ETS88029.1 - 4e-24 85.3 0.0 3.2e-15 56.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 ETS88029.1 - 0.0021 18.0 0.4 0.0081 16.1 0.4 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ETS88029.1 - 0.11 11.4 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 ETS88029.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FKBP_C PF00254.28 ETS88030.1 - 3.6e-32 110.5 0.1 1.2e-31 108.9 0.0 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 ETS88030.1 - 1.6e-30 105.7 3.2 1.6e-30 105.7 3.2 2.5 2 1 0 2 2 2 1 Nucleoplasmin-like domain Mpp10 PF04006.12 ETS88030.1 - 1.5 7.1 45.5 2.2 6.6 45.5 1.1 1 0 0 1 1 1 0 Mpp10 protein DDHD PF02862.17 ETS88030.1 - 2.2 8.4 5.9 17 5.5 0.2 2.2 2 0 0 2 2 2 0 DDHD domain AF-4 PF05110.13 ETS88030.1 - 3.8 5.5 19.4 0.41 8.7 2.4 2.0 2 0 0 2 2 2 0 AF-4 proto-oncoprotein TFIIF_alpha PF05793.12 ETS88030.1 - 8 4.9 59.7 0.09 11.3 25.5 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DJ-1_PfpI PF01965.24 ETS88031.1 - 1.4e-10 41.2 0.0 1.7e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Glyco_trans_2_3 PF13632.6 ETS88032.1 - 1.3e-19 70.9 0.6 1.3e-19 70.9 0.6 1.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DUF4698 PF15769.5 ETS88032.1 - 0.094 11.8 0.5 0.15 11.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) FmiP_Thoc5 PF09766.9 ETS88033.1 - 7e-32 111.1 13.6 8.6e-32 110.8 13.6 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 SPATA1_C PF15743.5 ETS88033.1 - 0.0082 16.2 10.2 0.08 13.0 5.1 2.2 2 0 0 2 2 2 2 Spermatogenesis-associated C-terminus SusD_RagB PF07980.11 ETS88033.1 - 0.03 13.9 2.6 0.039 13.6 2.6 1.1 1 0 0 1 1 1 0 SusD family CENP-F_leu_zip PF10473.9 ETS88033.1 - 0.13 12.3 12.1 1.4 8.9 6.2 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3958 PF13125.6 ETS88033.1 - 0.39 10.9 13.3 1.2 9.3 7.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3958) BBS2_C PF14782.6 ETS88033.1 - 3.7 6.2 9.5 0.23 10.2 0.8 2.0 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal HlyIII PF03006.20 ETS88034.1 - 2.2e-61 207.4 18.2 2.7e-61 207.1 18.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.13 ETS88034.1 - 0.025 14.7 1.0 0.025 14.7 1.0 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF883 PF05957.13 ETS88034.1 - 0.28 11.8 10.0 0.91 10.2 2.6 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) RabGAP-TBC PF00566.18 ETS88036.1 - 1.6e-29 103.1 0.0 1.3e-24 87.1 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Sulfate_transp PF00916.20 ETS88037.1 - 2.8e-107 358.8 22.0 3.6e-107 358.4 22.0 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ETS88037.1 - 1.1e-08 34.7 0.0 2.2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ETS88037.1 - 0.016 15.6 3.1 0.016 15.6 3.1 3.1 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily SNN_transmemb PF09049.10 ETS88037.1 - 4.6 7.3 9.2 0.38 10.7 2.4 2.9 2 0 0 2 2 2 0 Stannin transmembrane SWIM PF04434.17 ETS88038.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 SWIM zinc finger Glyco_hydro_16 PF00722.21 ETS88039.1 - 1.9e-10 40.5 1.1 2.8e-10 40.0 0.4 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_transf_34 PF05637.12 ETS88041.1 - 3.1e-65 220.3 3.2 3.9e-65 219.9 3.2 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Fungal_trans PF04082.18 ETS88043.1 - 2.1e-10 40.1 0.0 3.5e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS88043.1 - 3.5e-08 33.4 7.9 6.4e-08 32.6 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 ETS88043.1 - 0.71 10.0 13.9 0.15 12.2 8.9 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 ETS88043.1 - 2.8 7.9 11.7 0.048 13.6 4.6 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit URO-D PF01208.17 ETS88045.1 - 7.3e-121 403.5 0.0 8.2e-121 403.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) FR47 PF08445.10 ETS88046.1 - 8e-05 22.5 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ETS88046.1 - 0.0037 17.9 0.0 0.0066 17.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ETS88046.1 - 0.039 14.2 0.0 0.07 13.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Gly_acyl_tr_C PF08444.10 ETS88046.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region DUF3602 PF12223.8 ETS88047.1 - 1.1e-15 58.0 12.2 5.8e-13 49.2 0.9 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) Velvet PF11754.8 ETS88048.1 - 1.1e-83 281.1 0.0 1.1e-83 281.1 0.0 2.0 2 0 0 2 2 2 1 Velvet factor RhoGEF PF00621.20 ETS88049.1 - 3.7e-31 108.8 0.1 1.7e-30 106.6 0.1 2.2 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.18 ETS88049.1 - 1.3e-08 34.8 0.9 1.3e-08 34.8 0.9 2.7 3 0 0 3 3 3 1 BAR domain Telomerase_RBD PF12009.8 ETS88050.1 - 2.1e-50 170.3 0.9 4.4e-50 169.3 0.9 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 ETS88050.1 - 4.6e-13 49.2 0.0 1.3e-10 41.2 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) MT PF12777.7 ETS88050.1 - 0.039 13.0 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor MFS_2 PF13347.6 ETS88051.1 - 4.7e-11 41.9 8.3 4.7e-11 41.9 8.3 2.8 3 1 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 ETS88051.1 - 7.6e-06 25.0 2.1 1.8e-05 23.8 2.1 1.6 1 0 0 1 1 1 1 MFS_1 like family PUCC PF03209.15 ETS88051.1 - 0.0011 18.1 3.8 0.0022 17.1 3.8 1.4 1 0 0 1 1 1 1 PUCC protein DUF3382 PF11862.8 ETS88051.1 - 0.48 10.7 4.3 13 6.1 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) DUF3087 PF11286.8 ETS88051.1 - 0.56 9.7 3.2 1.1 8.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) HisG PF01634.18 ETS88052.1 - 2e-56 190.4 0.1 3e-56 189.8 0.1 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 ETS88052.1 - 5.8e-28 96.8 0.3 1.4e-27 95.7 0.3 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain DUF3837 PF12939.7 ETS88052.1 - 0.083 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) BCHF PF07284.11 ETS88053.1 - 0.016 15.2 0.0 0.036 14.1 0.0 1.5 2 0 0 2 2 2 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) MBOAT_2 PF13813.6 ETS88054.1 - 7.8e-19 67.7 4.6 7.8e-19 67.7 4.6 2.5 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family 7tm_2 PF00002.24 ETS88055.1 - 5.1e-06 26.0 19.3 5.2e-05 22.7 19.3 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Cellulase PF00150.18 ETS88056.1 - 3e-37 128.6 0.0 3.6e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_15 PF00723.21 ETS88057.1 - 9.5e-53 179.6 0.0 1.4e-47 162.6 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 F-box-like PF12937.7 ETS88058.1 - 0.00012 21.9 0.1 0.00025 20.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ETS88058.1 - 0.029 14.2 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 F-box domain Bromo_TP PF07524.13 ETS88059.1 - 1.3e-05 25.1 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated DUF2164 PF09932.9 ETS88059.1 - 0.0043 17.1 0.0 0.0092 16.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2164) POTRA_TamA_1 PF17243.2 ETS88059.1 - 0.055 13.6 0.3 0.17 12.0 0.1 1.9 2 0 0 2 2 2 0 POTRA domain TamA domain 1 TAFII55_N PF04658.13 ETS88060.1 - 6e-45 152.8 0.1 1.2e-44 151.9 0.1 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region DUF3450 PF11932.8 ETS88060.1 - 0.0024 17.2 2.1 0.0041 16.5 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Pox_A_type_inc PF04508.12 ETS88060.1 - 0.07 13.0 0.0 0.07 13.0 0.0 2.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Cwf_Cwc_15 PF04889.12 ETS88060.1 - 0.086 12.6 30.0 0.34 10.6 13.1 3.1 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_L37 PF08561.10 ETS88061.1 - 4.7e-40 136.9 2.9 6.7e-40 136.4 2.9 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 FXR_C1 PF16096.5 ETS88061.1 - 0.015 15.5 0.3 0.041 14.1 0.0 1.9 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 NDUFB10 PF10249.9 ETS88062.1 - 0.0054 17.2 0.0 0.0063 17.0 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.14 ETS88062.1 - 0.18 12.6 0.0 0.27 11.9 0.0 1.3 1 0 0 1 1 1 0 HWE histidine kinase RRM_1 PF00076.22 ETS88063.1 - 5.1e-37 125.5 0.6 4.5e-18 64.8 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ETS88063.1 - 0.0003 20.9 0.0 0.77 9.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif DUF1752 PF08550.10 ETS88064.1 - 3.6e-10 39.5 7.1 7.2e-10 38.5 7.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Met_10 PF02475.16 ETS88065.1 - 1e-76 257.1 0.0 1.3e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 ETS88065.1 - 0.17 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase 2OG-FeII_Oxy_2 PF13532.6 ETS88066.1 - 8.9e-27 94.5 0.0 1.7e-26 93.7 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Prenyltransf PF01255.19 ETS88067.1 - 0.0022 17.6 0.0 0.021 14.4 0.0 2.0 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Herpes_US12 PF05363.12 ETS88067.1 - 0.0029 18.3 0.5 14 6.5 0.3 3.2 3 0 0 3 3 3 2 Herpesvirus US12 family Sec10 PF07393.11 ETS88068.1 - 3.1e-221 736.6 1.0 3.7e-221 736.4 1.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF1564 PF07600.11 ETS88068.1 - 0.075 12.7 1.0 0.32 10.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) RuvB_C PF05491.13 ETS88068.1 - 0.13 12.1 0.1 18 5.3 0.0 2.8 2 0 0 2 2 2 0 RuvB C-terminal winged helix domain Phage_TAC_3 PF06896.11 ETS88068.1 - 0.15 12.7 1.9 21 5.8 0.0 3.6 3 0 0 3 3 3 0 Phage tail assembly chaperone proteins, TAC Homeodomain PF00046.29 ETS88069.1 - 9.2e-15 54.2 2.1 2.5e-14 52.9 2.1 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ETS88069.1 - 0.084 12.8 0.3 0.2 11.6 0.3 1.6 1 0 0 1 1 1 0 Homeobox KN domain NAD_kinase PF01513.21 ETS88070.1 - 3.6e-81 272.6 0.0 4.9e-81 272.1 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.21 ETS88071.1 - 7.5e-12 45.9 0.1 2.2e-11 44.4 0.0 1.7 1 1 1 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ETS88071.1 - 0.0099 15.9 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 HalOD1 PF18545.1 ETS88071.1 - 0.022 15.0 0.0 0.06 13.6 0.0 1.8 1 0 0 1 1 1 0 Halobacterial output domain 1 PTPA PF03095.15 ETS88072.1 - 1.5e-113 379.2 0.0 1.8e-113 379.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Glyco_hydro_2_C PF02836.17 ETS88073.1 - 1.9e-103 345.8 0.1 2.6e-103 345.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 ETS88073.1 - 2.8e-66 223.6 0.4 1.8e-65 221.0 0.1 2.2 2 0 0 2 2 2 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 ETS88073.1 - 2.1e-45 154.7 0.4 6e-45 153.2 0.3 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 ETS88073.1 - 5.6e-17 62.0 0.0 1.8e-16 60.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 ETS88073.1 - 2e-13 51.0 0.0 5.6e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 ETS88073.1 - 0.00043 20.8 0.0 0.0014 19.2 0.0 1.9 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Erg28 PF03694.13 ETS88074.1 - 1.4e-21 76.9 0.3 1.7e-21 76.7 0.3 1.1 1 0 0 1 1 1 1 Erg28 like protein IBR PF01485.21 ETS88075.1 - 5.6e-11 42.5 7.2 5.6e-11 42.5 7.2 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain OPT PF03169.15 ETS88076.1 - 3.5e-179 597.4 59.0 4e-179 597.2 59.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CorA PF01544.18 ETS88077.1 - 2e-08 33.9 0.4 2e-08 33.9 0.4 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF759 PF05537.11 ETS88077.1 - 0.011 14.6 0.3 0.018 14.0 0.3 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) Sugar_tr PF00083.24 ETS88078.1 - 2e-43 148.9 16.1 2.8e-43 148.4 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ETS88078.1 - 4.6e-34 117.9 28.7 5.1e-34 117.7 27.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ETS88078.1 - 4.3e-05 22.5 12.4 0.032 13.1 2.0 3.5 1 1 2 3 3 3 3 MFS_1 like family Aldolase_II PF00596.21 ETS88080.1 - 2.1e-47 161.5 0.2 2.5e-47 161.2 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TauD PF02668.16 ETS88081.1 - 1.4e-43 149.7 0.3 6.9e-43 147.4 0.3 1.8 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans_2 PF11951.8 ETS88082.1 - 2e-14 53.3 7.1 3.1e-11 42.7 2.5 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS88082.1 - 1.6e-07 31.3 11.8 4e-07 30.1 11.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 ETS88083.1 - 0.028 14.3 0.3 0.078 12.9 0.3 1.8 1 0 0 1 1 1 0 F-box-like DIOX_N PF14226.6 ETS88084.1 - 4e-27 95.3 0.0 5.8e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ETS88084.1 - 5.6e-19 68.5 0.0 9.7e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.15 ETS88085.1 - 1.2e-46 159.5 14.4 1.5e-46 159.1 14.4 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin OPT PF03169.15 ETS88086.1 - 3.5e-120 402.5 47.8 4.1e-120 402.3 47.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PrgI PF12666.7 ETS88086.1 - 1 10.1 0.0 1 10.1 0.0 4.4 3 1 1 4 4 4 0 PrgI family protein CorA PF01544.18 ETS88087.1 - 4.4e-06 26.2 0.2 7.2e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Pkinase PF00069.25 ETS88088.1 - 3.9e-19 69.1 0.0 1.3e-18 67.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS88088.1 - 2.5e-07 30.3 0.0 4.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ETS88089.1 - 2e-22 79.8 0.0 4.6e-21 75.4 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ETS88089.1 - 8.5e-13 48.2 0.0 3.6e-12 46.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase AAA_lid_11 PF18198.1 ETS88089.1 - 0.1 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain ABC_membrane_2 PF06472.15 ETS88090.1 - 0.12 11.8 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 AT_hook PF02178.19 ETS88090.1 - 1.5 8.9 17.6 6.3 7.0 4.0 3.4 2 0 0 2 2 2 0 AT hook motif V-ATPase_C PF03223.15 ETS88091.1 - 7.5e-123 410.6 0.1 8.3e-123 410.4 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C APS_kinase PF01583.20 ETS88092.1 - 8.6e-72 240.2 0.0 1.1e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 ETS88092.1 - 1.2e-05 25.5 0.0 2.4e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ETS88092.1 - 0.00017 22.1 0.0 0.00028 21.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 ETS88092.1 - 0.00054 19.5 0.0 0.00099 18.6 0.0 1.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 6PF2K PF01591.18 ETS88092.1 - 0.043 13.1 0.0 0.096 12.0 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase G-alpha PF00503.20 ETS88092.1 - 0.052 12.7 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit T_hemolysin PF12261.8 ETS88092.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Thermostable hemolysin AAA_29 PF13555.6 ETS88092.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ETS88092.1 - 0.089 13.2 0.1 0.14 12.5 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain Dmrt1 PF12374.8 ETS88092.1 - 0.12 12.8 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 Cytidylate_kin PF02224.18 ETS88092.1 - 0.15 11.8 0.0 3 7.5 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase DUF463 PF04317.12 ETS88092.1 - 0.16 10.8 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 Peroxidase_2 PF01328.17 ETS88094.1 - 2.4e-50 171.7 0.1 2.8e-50 171.5 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 DUF5331 PF17265.2 ETS88094.1 - 0.061 13.1 0.0 15 5.4 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5331) Uso1_p115_C PF04871.13 ETS88095.1 - 0.094 13.1 0.0 0.57 10.6 0.0 1.9 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region 4HBT PF03061.22 ETS88097.1 - 5.3e-12 45.9 0.0 1.1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily HupF_HypC PF01455.18 ETS88097.1 - 0.11 12.6 0.0 0.36 11.0 0.0 1.8 1 1 1 2 2 2 0 HupF/HypC family Imm43 PF15570.6 ETS88098.1 - 0.075 13.1 0.1 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 43 CBF PF03914.17 ETS88099.1 - 5.2e-52 176.3 0.1 5.2e-52 176.3 0.1 3.3 5 0 0 5 5 5 1 CBF/Mak21 family Mo25 PF08569.11 ETS88099.1 - 0.034 13.5 0.2 0.069 12.5 0.2 1.4 1 0 0 1 1 1 0 Mo25-like BUD22 PF09073.10 ETS88099.1 - 0.49 9.7 55.2 0.14 11.4 8.9 3.6 4 0 0 4 4 4 0 BUD22 tRNA-synt_2b PF00587.25 ETS88100.1 - 4.4e-33 114.7 0.0 7.5e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ETS88100.1 - 1e-08 35.2 0.0 2.2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain DnaJ PF00226.31 ETS88101.1 - 1.7e-22 79.3 0.2 2e-13 50.3 0.0 3.0 2 2 0 2 2 2 2 DnaJ domain RAG1_imp_bd PF12560.8 ETS88101.1 - 0.15 11.6 0.2 0.22 11.0 0.2 1.2 1 0 0 1 1 1 0 RAG1 importin binding DUF2963 PF11178.8 ETS88103.1 - 0.1 12.3 0.4 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) Ribosomal_L5_C PF00673.21 ETS88104.1 - 4.7e-22 78.0 0.0 6.9e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ETS88104.1 - 2.5e-20 72.6 0.0 8.2e-20 70.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.22 ETS88105.1 - 2.4e-17 62.4 0.0 3.6e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain CPSase_L_D2 PF02786.17 ETS88106.1 - 1.9e-81 272.6 0.7 3.2e-81 271.9 0.7 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 ETS88106.1 - 8.4e-71 237.8 0.1 4e-70 235.6 0.0 2.0 2 0 0 2 2 2 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 ETS88106.1 - 8.8e-38 129.2 0.0 1.8e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ETS88106.1 - 4.9e-31 107.0 0.0 1.3e-30 105.7 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 ETS88106.1 - 7.6e-26 91.2 0.0 1.9e-25 90.0 0.0 1.7 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 ETS88106.1 - 1e-18 66.9 4.1 1.2e-18 66.7 2.1 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ETS88106.1 - 6.2e-10 38.7 1.1 1.5e-06 27.9 0.1 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 ETS88106.1 - 4.6e-09 36.1 0.0 9.3e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ETS88106.1 - 3.9e-07 29.8 0.1 7.4e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 ETS88106.1 - 2.9e-05 24.2 0.0 6.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 ETS88106.1 - 5.4e-05 22.9 0.0 0.00033 20.3 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 ETS88106.1 - 0.0011 18.3 0.0 0.16 11.2 0.0 2.5 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 ETS88106.1 - 0.01 16.5 0.1 13 6.6 0.0 3.3 3 0 0 3 3 3 0 HlyD family secretion protein ATP-grasp_4 PF13535.6 ETS88106.1 - 0.014 15.0 0.1 0.037 13.6 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_ST PF14397.6 ETS88106.1 - 0.06 12.6 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp NQRA PF05896.11 ETS88106.1 - 0.11 12.0 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GCV_H PF01597.19 ETS88106.1 - 0.28 11.1 0.7 0.96 9.3 0.1 2.2 2 0 0 2 2 2 0 Glycine cleavage H-protein MPC PF03650.13 ETS88107.1 - 5.6e-19 68.3 0.1 6.4e-19 68.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Clathrin PF00637.20 ETS88108.1 - 1.7e-193 634.2 24.4 6.7e-32 110.3 1.9 7.6 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 ETS88108.1 - 4.4e-33 112.0 0.2 8.4e-06 25.9 0.0 6.9 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 ETS88108.1 - 4.7e-32 109.7 1.5 1.4e-31 108.2 0.2 2.7 2 0 0 2 2 2 1 Clathrin-H-link TPR_7 PF13176.6 ETS88108.1 - 0.00064 19.6 8.4 2.6 8.3 0.1 7.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 ETS88108.1 - 0.0016 19.1 19.6 3.8 8.6 0.1 8.8 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 ETS88108.1 - 0.0046 17.2 3.7 24 5.3 0.1 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 ETS88108.1 - 0.035 13.9 5.0 16 5.5 0.4 5.6 4 0 0 4 4 4 0 Tetratricopeptide repeat VapB_antitoxin PF09957.9 ETS88108.1 - 0.11 12.4 0.0 0.53 10.2 0.0 2.2 1 0 0 1 1 1 0 Bacterial antitoxin of type II TA system, VapB MIT PF04212.18 ETS88108.1 - 0.18 11.9 2.7 1.6 8.8 0.2 3.8 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain Clathrin-link PF09268.10 ETS88108.1 - 0.2 11.0 3.9 0.23 10.8 1.3 2.4 2 0 0 2 2 2 0 Clathrin, heavy-chain linker TPR_8 PF13181.6 ETS88108.1 - 0.24 11.7 13.8 0.98 9.8 0.0 6.1 7 0 0 7 7 5 0 Tetratricopeptide repeat PPR PF01535.20 ETS88108.1 - 0.4 11.0 1.6 53 4.4 0.0 4.1 3 0 0 3 3 3 0 PPR repeat TPR_2 PF07719.17 ETS88108.1 - 7.5 6.9 17.2 51 4.3 0.0 7.6 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF1640 PF07798.11 ETS88109.1 - 5.3e-57 192.7 9.6 6.4e-57 192.4 9.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) GNAT_acetyltr_2 PF13718.6 ETS88109.1 - 0.0054 16.2 1.4 0.018 14.5 0.1 2.0 1 1 1 2 2 2 1 GNAT acetyltransferase 2 PseudoU_synth_1 PF01416.20 ETS88109.1 - 0.14 12.7 0.4 1.6 9.2 0.1 2.4 1 1 2 3 3 3 0 tRNA pseudouridine synthase DUF4808 PF16066.5 ETS88109.1 - 0.14 12.7 1.1 0.23 12.0 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4808) cwf21 PF08312.12 ETS88109.1 - 0.49 10.6 5.2 0.44 10.7 3.3 2.0 2 1 0 2 2 2 0 cwf21 domain HU-CCDC81_bac_2 PF18175.1 ETS88109.1 - 0.52 10.2 2.4 2 8.3 0.9 2.3 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 Metal_resist PF13801.6 ETS88109.1 - 2.5 8.3 10.9 0.16 12.2 3.7 2.6 1 1 3 4 4 4 0 Heavy-metal resistance DLP_helical PF18709.1 ETS88109.1 - 3.7 6.7 10.8 12 4.9 10.8 1.7 1 1 0 1 1 1 0 Dynamin-like helical domain BST2 PF16716.5 ETS88109.1 - 4.7 7.9 12.4 1.4 9.5 1.1 2.5 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Mod_r PF07200.13 ETS88110.1 - 8.3e-36 123.3 5.9 1e-35 123.0 5.9 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein MerR PF00376.23 ETS88110.1 - 0.016 15.0 0.1 0.043 13.6 0.1 1.8 1 0 0 1 1 1 0 MerR family regulatory protein NAD_binding_1 PF00175.21 ETS88110.1 - 0.64 10.7 2.3 1.1 10.0 0.5 2.0 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain F-box PF00646.33 ETS88112.1 - 2.5e-05 24.0 0.1 5.7e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ETS88112.1 - 0.00085 19.2 0.5 0.0021 17.9 0.0 1.9 2 0 0 2 2 2 1 F-box-like NAD_binding_10 PF13460.6 ETS88113.1 - 1.6e-05 24.9 0.2 5.2e-05 23.2 0.0 1.9 2 1 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ETS88113.1 - 0.0011 18.0 0.0 0.0015 17.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ETS88113.1 - 0.0031 17.0 0.0 0.007 15.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3328 PF11807.8 ETS88115.1 - 8.1e-49 166.4 2.7 1e-48 166.1 2.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 ETS88116.1 - 1.1e-19 71.2 10.0 6.9e-19 68.5 10.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 ETS88117.1 - 5.5e-31 108.1 0.0 6.5e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 ETS88118.1 - 5.4e-32 111.4 0.1 9.2e-32 110.6 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 ETS88119.1 - 7.3e-06 25.9 0.1 8.4e-06 25.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) HET PF06985.11 ETS88120.1 - 1.3e-27 96.9 2.1 1.2e-25 90.5 2.1 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SDA1 PF05285.12 ETS88120.1 - 0.15 11.5 26.8 0.21 11.0 26.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 ETS88120.1 - 0.25 9.5 29.7 0.35 9.0 29.7 1.1 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 ETS88120.1 - 0.26 10.5 6.0 0.36 10.0 6.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 ETS88120.1 - 0.49 8.6 18.0 0.77 8.0 18.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 ETS88120.1 - 0.54 9.0 6.8 0.76 8.6 6.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RR_TM4-6 PF06459.12 ETS88120.1 - 0.74 9.6 8.7 1.1 9.0 8.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRN3 PF05327.11 ETS88120.1 - 0.78 8.2 12.0 1.5 7.3 12.0 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF913 PF06025.12 ETS88120.1 - 1.3 7.9 4.5 2.2 7.2 4.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Mpp10 PF04006.12 ETS88120.1 - 1.6 7.1 25.7 2.2 6.6 25.7 1.1 1 0 0 1 1 1 0 Mpp10 protein Paf1 PF03985.13 ETS88120.1 - 2.3 7.1 18.2 3.9 6.4 18.2 1.3 1 0 0 1 1 1 0 Paf1 Raftlin PF15250.6 ETS88120.1 - 3.2 6.4 7.8 4.8 5.8 7.8 1.2 1 0 0 1 1 1 0 Raftlin SAPS PF04499.15 ETS88120.1 - 5.2 5.7 10.5 7.4 5.2 10.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SpoIIIAH PF12685.7 ETS88120.1 - 7.7 6.3 12.5 12 5.7 12.5 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Nup84_Nup100 PF04121.13 ETS88121.1 - 1e-171 572.7 0.0 1.2e-171 572.5 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Rad60-SLD PF11976.8 ETS88122.1 - 2.4e-19 68.9 0.1 2.8e-19 68.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ETS88122.1 - 1.3e-10 40.8 0.1 1.5e-10 40.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family LIM PF00412.22 ETS88123.1 - 1.8e-25 88.9 19.8 5.2e-08 33.0 1.2 3.3 3 0 0 3 3 3 3 LIM domain DUF2321 PF10083.9 ETS88123.1 - 0.047 13.3 0.3 0.047 13.3 0.3 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) MFS_1 PF07690.16 ETS88124.1 - 2.8e-24 85.7 76.2 2.3e-19 69.6 48.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NPR3 PF03666.13 ETS88125.1 - 1.1e-140 469.5 0.0 2e-140 468.7 0.0 1.4 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 EC042_2821 PF18740.1 ETS88125.1 - 0.095 12.6 0.3 0.18 11.7 0.3 1.3 1 0 0 1 1 1 0 EC042_2821-lke REase HLH PF00010.26 ETS88126.1 - 5.5e-13 48.7 0.0 4.7e-12 45.7 0.0 2.4 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain Got1 PF04178.12 ETS88127.1 - 1e-34 119.3 14.4 1.4e-34 118.9 14.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family La PF05383.17 ETS88128.1 - 3.3e-14 52.7 0.1 5.7e-14 51.9 0.1 1.3 1 0 0 1 1 1 1 La domain Fungal_trans PF04082.18 ETS88129.1 - 1.9e-20 73.0 0.1 4.5e-20 71.8 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ETS88129.1 - 1.5e-09 37.8 9.8 4.6e-09 36.3 9.8 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ligase_CoA PF00549.19 ETS88130.1 - 4.4e-34 117.5 3.4 2.2e-18 66.6 0.3 2.5 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 ETS88130.1 - 3.9e-17 62.7 0.2 1.4e-16 61.0 0.2 2.0 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 ETS88130.1 - 8.5e-10 38.6 0.1 1.2e-06 28.4 0.0 2.7 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain CHCH PF06747.13 ETS88131.1 - 0.00041 20.4 0.5 0.00058 19.9 0.5 1.3 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.13 ETS88131.1 - 0.017 15.5 2.1 1.6 9.2 0.2 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) GCK PF07802.11 ETS88131.1 - 0.019 15.4 0.5 0.028 14.8 0.5 1.2 1 0 0 1 1 1 0 GCK domain Pet191_N PF10203.9 ETS88131.1 - 0.027 14.8 1.9 0.093 13.1 1.9 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DUF3546 PF12066.8 ETS88133.1 - 3.9e-32 110.7 4.6 3.9e-32 110.7 4.6 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 ETS88133.1 - 3e-13 50.6 1.8 7.5e-13 49.3 0.8 2.2 2 0 0 2 2 2 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 ETS88133.1 - 5.5e-12 45.3 0.1 1.2e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Rax2 PF12768.7 ETS88134.1 - 1.2e-73 247.2 8.4 1.9e-71 239.9 0.2 4.5 4 0 0 4 4 4 3 Cortical protein marker for cell polarity Kelch_4 PF13418.6 ETS88134.1 - 0.024 14.7 0.6 0.024 14.7 0.6 4.0 3 1 1 4 4 4 0 Galactose oxidase, central domain SNase PF00565.17 ETS88135.1 - 1.5e-24 86.5 0.0 2e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue PKD_channel PF08016.12 ETS88136.1 - 0.25 10.0 10.2 1.5 7.4 2.1 2.2 2 0 0 2 2 2 0 Polycystin cation channel OGG_N PF07934.12 ETS88137.1 - 2.4e-34 118.0 0.0 3.9e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 ETS88137.1 - 6.5e-17 62.0 0.0 1.1e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ETS88137.1 - 0.00015 21.4 0.0 0.00046 19.9 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.22 ETS88138.1 - 2.7e-26 91.2 0.1 2.2e-12 46.6 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ETS88138.1 - 0.0012 18.6 0.0 1.4 8.8 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif TcpA PF05946.12 ETS88138.1 - 0.043 13.9 0.1 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 Toxin-coregulated pilus subunit TcpA APH PF01636.23 ETS88139.1 - 1.1e-42 146.7 0.0 2.1e-42 145.7 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 ETS88139.1 - 5.3e-05 22.7 0.0 8.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 ETS88139.1 - 0.027 14.0 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 ETS88139.1 - 0.093 11.6 0.1 0.36 9.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) RIO1 PF01163.22 ETS88139.1 - 0.18 11.4 0.0 18 4.9 0.0 2.3 2 0 0 2 2 2 0 RIO1 family SesA PF17107.5 ETS88140.1 - 3.5e-06 27.2 0.5 5.3e-06 26.6 0.5 1.3 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 ETS88140.1 - 5.5e-05 22.6 0.0 8.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins PGA_cap PF09587.10 ETS88140.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap V-SNARE PF05008.15 ETS88140.1 - 0.13 12.6 0.1 0.28 11.6 0.1 1.5 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus p450 PF00067.22 ETS88141.1 - 5.9e-57 193.4 0.0 7.9e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 4HBT_3 PF13622.6 ETS88142.1 - 1.4e-47 163.0 0.5 1.8e-47 162.7 0.5 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 ETS88142.1 - 6.6e-10 38.9 0.0 3e-08 33.6 0.0 2.4 2 1 1 3 3 3 1 Acyl-CoA thioesterase Zn_clus PF00172.18 ETS88143.1 - 1.5e-07 31.4 8.8 2.7e-07 30.6 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS88143.1 - 5.1e-07 29.0 0.4 8.4e-07 28.3 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2471 PF10616.9 ETS88143.1 - 0.083 13.4 0.6 4 8.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2471) Flavoprotein PF02441.19 ETS88144.1 - 4.5e-25 88.2 0.2 5.6e-25 87.9 0.2 1.1 1 0 0 1 1 1 1 Flavoprotein UbiD PF01977.16 ETS88145.1 - 4.9e-126 420.9 0.0 5.6e-126 420.7 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase ADH_zinc_N_2 PF13602.6 ETS88146.1 - 5.3e-11 43.7 0.0 1.1e-10 42.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ETS88146.1 - 9.8e-11 41.5 0.0 2.2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ETS88146.1 - 8.5e-08 32.2 0.4 2e-07 31.1 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF3176 PF11374.8 ETS88147.1 - 7.3e-30 103.3 0.6 1.7e-29 102.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Ank_2 PF12796.7 ETS88148.1 - 2.9e-18 66.2 5.1 1.9e-05 25.1 0.0 7.5 6 2 0 7 7 7 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ETS88148.1 - 2.7e-16 58.0 13.5 0.011 16.2 0.1 10.5 11 0 0 11 11 11 3 Ankyrin repeat Ank_4 PF13637.6 ETS88148.1 - 7.2e-16 58.3 4.9 0.0021 18.6 0.0 8.2 6 2 3 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 ETS88148.1 - 9.6e-08 32.2 10.4 0.2 12.0 0.0 6.9 9 0 0 9 9 9 3 Ankyrin repeats (many copies) Clr5 PF14420.6 ETS88148.1 - 3.3e-06 27.2 0.1 8.1e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 Clr5 domain Ank PF00023.30 ETS88148.1 - 9.4e-05 22.7 24.2 0.057 13.9 0.9 9.0 10 0 0 10 10 10 3 Ankyrin repeat Zn_clus PF00172.18 ETS88150.1 - 2e-09 37.4 8.4 3.4e-09 36.7 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep57_MT_bd PF06657.13 ETS88150.1 - 0.0041 17.5 0.2 0.55 10.7 0.0 2.9 2 1 1 3 3 3 1 Centrosome microtubule-binding domain of Cep57 Trimer_CC PF08954.11 ETS88150.1 - 0.052 13.1 1.4 0.41 10.2 0.1 2.5 2 0 0 2 2 2 0 Trimerisation motif MFS_1 PF07690.16 ETS88151.1 - 4.4e-21 75.2 19.9 5.3e-21 74.9 19.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS88151.1 - 2.3e-09 36.6 5.8 2.5e-09 36.5 5.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 ETS88151.1 - 1.4e-06 26.9 2.4 1.4e-06 26.9 2.4 1.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 ETS88152.1 - 1e-05 24.7 37.4 1e-05 24.7 37.4 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Myco_arth_vir_N PF09610.10 ETS88152.1 - 0.05 13.7 0.3 0.05 13.7 0.3 2.7 3 0 0 3 3 3 0 Mycoplasma virulence signal region (Myco_arth_vir_N) BRCT PF00533.26 ETS88152.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Dioxygenase_C PF00775.21 ETS88153.1 - 2.9e-06 26.8 0.1 4.3e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase Abhydrolase_6 PF12697.7 ETS88154.1 - 1.3e-25 91.3 0.1 1.6e-25 91.1 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ETS88154.1 - 3.3e-06 26.9 0.1 0.071 12.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ETS88154.1 - 0.0017 17.7 0.0 0.47 9.7 0.0 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 ETS88154.1 - 0.0036 16.4 0.0 0.008 15.2 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 ETS88154.1 - 0.0075 15.2 0.0 0.036 13.0 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.18 ETS88154.1 - 0.032 13.8 0.0 7.4 6.1 0.0 2.7 3 1 0 3 3 3 0 Dienelactone hydrolase family PGAP1 PF07819.13 ETS88154.1 - 0.096 12.4 0.6 0.16 11.6 0.6 1.5 1 1 0 1 1 1 0 PGAP1-like protein Phage_RpbA PF10789.9 ETS88154.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.5 1 1 0 1 1 1 0 Phage RNA polymerase binding, RpbA Pec_lyase_C PF00544.19 ETS88155.1 - 8.4e-19 68.0 6.2 4.5e-17 62.3 6.2 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 ETS88155.1 - 8.8e-07 28.9 12.1 0.0036 17.2 5.3 2.8 1 1 2 3 3 3 2 Right handed beta helix region Acyl-CoA_dh_1 PF00441.24 ETS88156.1 - 4.4e-27 95.1 0.1 7.3e-27 94.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ETS88156.1 - 1.6e-12 48.1 0.0 8.4e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ETS88156.1 - 1.5e-05 25.1 0.0 3.6e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ETS88156.1 - 0.00013 22.2 0.0 0.00023 21.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.16 ETS88157.1 - 8.4e-39 133.5 27.1 8.4e-39 133.5 27.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS88157.1 - 7.8e-13 48.1 7.6 7.8e-13 48.1 7.6 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ETS88157.1 - 0.00046 18.8 1.9 0.00075 18.0 1.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.18 ETS88158.1 - 1.8e-07 31.2 8.1 4.1e-07 30.0 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ETS88158.1 - 2.2e-06 26.9 0.1 4.5e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cyt-b5 PF00173.28 ETS88160.1 - 1.8e-12 47.2 0.0 2.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_15 PF01793.16 ETS88161.1 - 1.2e-92 310.6 6.2 2.1e-92 309.9 6.2 1.3 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EXS PF03124.14 ETS88162.1 - 6.6e-113 377.4 12.6 7.5e-113 377.2 12.6 1.0 1 0 0 1 1 1 1 EXS family TMEM252 PF15664.5 ETS88162.1 - 0.053 13.2 0.1 0.088 12.5 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 252 family Pex2_Pex12 PF04757.14 ETS88163.1 - 6.9e-43 146.8 2.7 9e-43 146.5 2.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 ETS88163.1 - 3.8e-12 45.8 8.6 6.3e-12 45.1 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ETS88163.1 - 1.3e-11 44.7 9.1 2.3e-11 43.8 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ETS88163.1 - 3.7e-10 39.5 6.8 7.6e-10 38.5 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS88163.1 - 1.6e-09 37.5 9.7 2.5e-09 36.8 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS88163.1 - 1.6e-08 34.5 5.6 3.5e-08 33.3 5.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ETS88163.1 - 3.4e-07 30.1 5.7 6.2e-07 29.3 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ETS88163.1 - 6.4e-07 29.6 7.4 1.4e-06 28.5 7.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 ETS88163.1 - 3.2e-06 27.2 8.1 5.8e-06 26.4 8.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ETS88163.1 - 9.5e-06 25.4 10.4 1.6e-05 24.7 10.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 ETS88163.1 - 0.005 16.6 1.4 0.009 15.8 1.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 ETS88163.1 - 0.0056 16.8 9.2 0.011 15.9 9.2 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 ETS88163.1 - 0.0079 16.1 4.0 0.017 15.0 4.0 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 ETS88163.1 - 0.059 13.2 7.3 0.13 12.1 7.3 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 ETS88163.1 - 0.14 11.9 3.6 0.34 10.7 3.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 ETS88163.1 - 0.36 10.9 6.4 0.96 9.6 6.4 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Dioxygenase_C PF00775.21 ETS88164.1 - 1.3e-06 28.0 0.0 0.00029 20.3 0.0 2.4 2 0 0 2 2 2 2 Dioxygenase PALP PF00291.25 ETS88165.1 - 9e-60 202.6 0.1 9e-60 202.6 0.1 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.28 ETS88165.1 - 5.8e-26 91.5 0.0 1.8e-25 89.9 0.0 1.9 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ETS88165.1 - 1.1e-19 70.3 0.0 3e-19 68.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ETS88165.1 - 0.001 18.8 0.0 0.0098 15.6 0.1 2.3 2 0 0 2 2 2 1 Peptidase family M28 Glyco_hydro_18 PF00704.28 ETS88166.1 - 9e-61 206.3 1.2 2.1e-60 205.1 1.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 ETS88166.1 - 1.6e-11 44.5 12.6 1.6e-11 44.5 12.6 5.7 6 1 0 6 6 6 2 Chitin recognition protein LysM PF01476.20 ETS88167.1 - 1.3e-05 25.1 0.1 0.055 13.5 0.0 3.4 3 0 0 3 3 3 3 LysM domain LysM PF01476.20 ETS88169.1 - 8.6e-18 64.1 0.0 0.00038 20.5 0.0 4.3 4 0 0 4 4 4 4 LysM domain SapB_2 PF03489.17 ETS88169.1 - 0.014 15.5 0.2 3.4 7.9 0.3 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 2 Mucin PF01456.17 ETS88169.1 - 1.1 9.2 49.6 0.053 13.5 7.8 3.3 3 0 0 3 3 3 0 Mucin-like glycoprotein Fungal_trans PF04082.18 ETS88171.1 - 1.1e-16 60.7 1.8 3.9e-16 58.9 1.8 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.23 ETS88172.1 - 1.3e-56 192.3 0.0 1.6e-56 191.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 ETS88172.1 - 8.6e-07 29.7 0.0 1.8e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 ETS88172.1 - 0.077 12.6 0.0 6.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.16 ETS88173.1 - 1.6e-38 132.6 24.7 3.8e-37 128.0 24.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MSP1a PF11670.8 ETS88173.1 - 0.63 9.3 3.5 0.52 9.6 1.4 1.9 2 0 0 2 2 2 0 Major surface protein 1a (MSP1a) Amidohydro_1 PF01979.20 ETS88174.1 - 2.2e-60 204.8 0.5 2.6e-60 204.6 0.5 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS88174.1 - 3.8e-16 59.6 0.9 2.7e-11 43.6 0.1 2.5 2 1 0 2 2 2 2 Amidohydrolase family NACHT PF05729.12 ETS88175.1 - 4.4e-06 26.7 0.0 1.2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ETS88175.1 - 0.0033 17.8 0.1 0.021 15.2 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 ETS88175.1 - 0.1 13.0 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase NDUF_B8 PF05821.11 ETS88176.1 - 8.8e-08 32.2 0.1 1.4e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.23 ETS88177.1 - 1.3e-65 221.4 0.3 2.9e-65 220.3 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ETS88177.1 - 3e-19 69.4 0.0 1.8e-18 66.9 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ETS88177.1 - 4.8e-10 39.7 0.5 1.3e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HSA PF07529.13 ETS88177.1 - 0.0059 16.9 7.8 0.0059 16.9 7.8 3.0 1 1 2 3 3 3 1 HSA SCAN PF02023.17 ETS88177.1 - 0.041 13.7 3.3 0.15 11.9 1.6 2.5 2 0 0 2 2 2 0 SCAN domain Ribo_biogen_C PF04034.13 ETS88177.1 - 0.047 13.4 0.2 0.096 12.4 0.2 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein, C-terminal HDA2-3 PF11496.8 ETS88177.1 - 0.058 12.6 0.2 9.1 5.3 0.0 2.5 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 zf-HIT PF04438.16 ETS88178.1 - 1.2e-09 37.9 4.7 1.7e-09 37.3 4.7 1.3 1 0 0 1 1 1 1 HIT zinc finger Nicastrin PF05450.15 ETS88179.1 - 0.013 14.9 1.1 0.75 9.2 0.1 2.2 2 0 0 2 2 2 0 Nicastrin VRR_NUC PF08774.11 ETS88180.1 - 1.1e-23 83.4 0.0 2.3e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain MFS_1 PF07690.16 ETS88181.1 - 1.3e-36 126.3 48.5 6.1e-28 97.7 25.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily HTH_32 PF13565.6 ETS88182.1 - 0.0082 16.7 2.5 0.081 13.6 0.0 2.4 2 1 0 2 2 2 1 Homeodomain-like domain Dpy-30 PF05186.13 ETS88183.1 - 4.1e-15 55.2 0.0 6.2e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif Ribosomal_S13_N PF08069.12 ETS88184.1 - 4.4e-30 103.5 0.2 7.6e-30 102.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 ETS88184.1 - 1.5e-15 57.2 0.2 2.1e-15 56.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 ETS88184.1 - 0.023 14.6 0.1 0.059 13.3 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain WD40 PF00400.32 ETS88185.1 - 3.7e-46 154.2 27.9 6.4e-07 30.0 0.2 11.8 12 1 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.12 ETS88185.1 - 1.3e-19 70.4 0.4 2.9e-19 69.3 0.4 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 ETS88185.1 - 3.2e-17 62.6 9.1 0.017 15.4 0.1 9.3 5 2 4 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ETS88185.1 - 1.4e-06 27.3 0.4 0.3 9.7 0.0 5.7 6 0 0 6 6 6 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ETS88185.1 - 6.6e-06 25.3 0.5 0.07 12.1 0.0 4.8 5 1 0 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ETS88185.1 - 0.00033 20.6 0.1 0.35 10.7 0.0 3.6 3 1 1 4 4 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ETS88185.1 - 0.00079 18.8 0.0 9 5.5 0.0 3.9 4 0 0 4 4 4 2 WD40-like domain Nucleoporin_N PF08801.11 ETS88185.1 - 0.012 14.4 3.5 0.39 9.4 0.1 3.8 1 1 1 4 4 4 0 Nup133 N terminal like P34-Arc PF04045.14 ETS88186.1 - 5.3e-12 45.9 0.0 7.4e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc P34-Arc PF04045.14 ETS88187.1 - 7.8e-81 271.3 1.4 8.9e-81 271.1 1.4 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc SF3b1 PF08920.10 ETS88188.1 - 5.1e-23 81.8 5.1 5.1e-23 81.8 5.1 2.3 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 ETS88188.1 - 6.1e-12 45.8 2.2 0.011 16.2 0.0 7.5 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 ETS88188.1 - 1.7e-10 41.1 6.6 0.21 12.0 0.1 7.7 5 3 3 9 9 9 3 HEAT repeats HEAT PF02985.22 ETS88188.1 - 7.4e-09 35.1 7.1 0.75 10.2 0.0 8.9 9 0 0 9 9 9 2 HEAT repeat Cnd1 PF12717.7 ETS88188.1 - 3.9e-06 27.0 0.3 3.4 7.7 0.0 6.2 5 2 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ETS88188.1 - 0.00011 22.7 0.4 1.9 9.1 0.0 5.3 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 ETS88188.1 - 0.00012 20.8 0.1 0.074 11.6 0.0 3.1 2 2 0 3 3 3 2 Adaptin N terminal region DUF3385 PF11865.8 ETS88188.1 - 0.00018 21.4 0.1 0.064 13.2 0.0 4.7 6 1 0 6 6 6 1 Domain of unknown function (DUF3385) NUC173 PF08161.12 ETS88188.1 - 0.00061 19.5 0.6 1.1 8.9 0.0 4.0 4 1 1 5 5 5 2 NUC173 domain UNC45-central PF11701.8 ETS88188.1 - 0.011 15.7 0.0 0.036 14.0 0.0 1.9 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 ETS88188.1 - 0.012 15.2 0.2 0.9 9.0 0.0 3.4 4 0 0 4 4 4 0 CLASP N terminal DRIM PF07539.12 ETS88188.1 - 0.034 12.4 0.1 7.1 4.8 0.0 3.7 2 1 2 4 4 4 0 Down-regulated in metastasis zf-C2H2 PF00096.26 ETS88189.1 - 4.7e-10 39.3 12.4 2.6e-05 24.4 4.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ETS88189.1 - 1.5e-07 31.5 17.4 9.7e-05 22.6 0.6 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-met PF12874.7 ETS88189.1 - 7.3e-06 26.2 1.3 2.1e-05 24.7 1.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 ETS88189.1 - 0.00013 22.5 17.7 0.0015 19.2 3.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ETS88189.1 - 0.00014 21.8 2.4 0.00014 21.8 2.4 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ETS88189.1 - 0.00068 19.9 4.2 0.00087 19.5 1.8 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ETS88189.1 - 0.055 13.8 1.1 0.055 13.8 1.1 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 ETS88189.1 - 0.22 11.3 9.0 1.6 8.6 1.3 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 ETS88189.1 - 1.2 9.1 5.4 14 5.7 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type RAP1 PF07218.11 ETS88189.1 - 3.5 5.8 7.2 4.5 5.4 7.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LSM PF01423.22 ETS88192.1 - 0.00053 19.6 0.0 0.00072 19.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain Pkr1 PF08636.10 ETS88193.1 - 2.5e-32 110.8 3.9 3.3e-32 110.5 3.9 1.1 1 0 0 1 1 1 1 ER protein Pkr1 OAD_gamma PF04277.13 ETS88193.1 - 0.0038 17.8 2.8 0.014 15.9 2.8 2.2 1 1 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain PAP_PilO PF06864.12 ETS88193.1 - 0.0052 15.7 0.1 0.0064 15.4 0.1 1.1 1 0 0 1 1 1 1 Pilin accessory protein (PilO) FHIPEP PF00771.20 ETS88193.1 - 0.023 13.2 0.0 0.027 13.0 0.0 1.0 1 0 0 1 1 1 0 FHIPEP family Phage_Gp23 PF10669.9 ETS88193.1 - 0.52 10.7 8.6 0.42 11.0 2.8 2.6 2 1 0 2 2 2 0 Protein gp23 (Bacteriophage A118) zf-C2H2 PF00096.26 ETS88194.1 - 0.0031 17.9 3.7 0.28 11.7 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ETS88194.1 - 0.019 15.7 2.2 7.2 7.7 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 ETS88194.1 - 0.093 12.2 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain BRD4_CDT PF17105.5 ETS88194.1 - 9.6 5.9 7.2 19 4.9 7.2 1.4 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 Cullin PF00888.22 ETS88195.1 - 1.1e-22 80.5 0.1 2.1e-22 79.5 0.1 1.4 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 ETS88195.1 - 3.6e-22 78.6 1.6 8.7e-22 77.4 0.4 2.4 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 zf-RING_2 PF13639.6 ETS88196.1 - 3.8e-11 43.1 3.7 6.6e-11 42.4 3.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ETS88196.1 - 1.4e-09 38.1 2.5 3.1e-09 37.0 2.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ETS88196.1 - 1.7e-07 31.2 0.2 3.2e-07 30.3 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 ETS88196.1 - 1.1e-06 28.3 6.3 3.3e-06 26.8 6.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ETS88196.1 - 4.7e-05 23.3 2.1 4.9e-05 23.3 0.5 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 ETS88196.1 - 5e-05 23.2 1.8 9.1e-05 22.3 1.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ETS88196.1 - 0.00011 22.0 3.1 0.0002 21.2 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ETS88196.1 - 0.00021 21.1 3.0 0.0005 19.9 3.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ETS88196.1 - 0.0013 18.5 3.7 0.0022 17.8 3.1 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 ETS88196.1 - 0.016 15.1 0.4 0.036 13.9 0.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 ETS88196.1 - 0.03 14.0 0.7 0.03 14.0 0.7 1.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 ETS88196.1 - 0.098 12.8 6.9 0.84 9.9 5.0 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_11 PF17123.5 ETS88196.1 - 0.1 12.4 2.0 0.35 10.7 2.0 1.9 1 1 0 1 1 1 0 RING-like zinc finger zf-P11 PF03854.14 ETS88196.1 - 0.15 11.7 0.8 0.35 10.6 0.8 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.6 ETS88196.1 - 0.71 10.1 3.5 0.31 11.2 0.8 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Metallophos PF00149.28 ETS88197.1 - 3.4e-09 37.5 0.1 5e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ETS88197.1 - 7.1e-09 36.1 1.2 1.1e-06 29.0 1.2 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Transp_inhibit PF18791.1 ETS88197.1 - 0.15 11.6 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain UPF0242 PF06785.11 ETS88198.1 - 0.0015 18.7 10.9 0.0015 18.7 10.9 6.0 1 1 5 6 6 6 2 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 ETS88198.1 - 0.0096 16.0 15.4 0.0096 16.0 15.4 7.1 1 1 4 6 6 6 4 TPR/MLP1/MLP2-like protein ADIP PF11559.8 ETS88198.1 - 0.013 15.5 0.9 0.013 15.5 0.9 8.2 1 1 6 9 9 9 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 ETS88198.1 - 0.023 13.6 100.7 0.025 13.5 17.6 5.3 1 1 4 5 5 5 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 ETS88198.1 - 0.031 14.1 88.6 0.024 14.5 6.7 8.7 1 1 7 9 9 9 0 Phage minor structural protein GP20 CENP-F_leu_zip PF10473.9 ETS88198.1 - 0.18 11.8 103.0 1.6 8.7 19.4 7.5 1 1 7 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 ETS88198.1 - 9.3 6.3 57.0 0.43 10.6 0.9 7.7 2 2 8 10 10 10 0 Protein of unknown function (DUF1664) Methyltransf_11 PF08241.12 ETS88199.1 - 8.2e-21 74.5 0.0 1.4e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS88199.1 - 3.5e-19 69.3 0.0 6.5e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS88199.1 - 6.6e-18 65.0 0.0 9.6e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ETS88199.1 - 1.5e-16 60.5 0.0 2.1e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 ETS88199.1 - 9.5e-11 42.3 0.0 1.6e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ETS88199.1 - 1.7e-09 37.7 0.0 2.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ETS88199.1 - 0.00032 20.5 0.0 0.00044 20.1 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.16 ETS88199.1 - 0.00043 19.0 0.0 0.00086 18.0 0.0 1.5 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 ETS88199.1 - 0.00069 19.5 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 2 Hypothetical methyltransferase MetW PF07021.12 ETS88199.1 - 0.0022 17.6 0.0 0.0065 16.1 0.0 1.6 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW CheR PF01739.18 ETS88199.1 - 0.005 16.3 0.0 0.74 9.3 0.0 2.2 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain MTS PF05175.14 ETS88199.1 - 0.019 14.5 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 ETS88199.1 - 0.038 14.0 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 ETS88199.1 - 0.076 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CFEM PF05730.11 ETS88200.1 - 3.6e-12 46.2 12.7 6.8e-12 45.3 12.7 1.4 1 0 0 1 1 1 1 CFEM domain BES1_N PF05687.13 ETS88201.1 - 0.22 11.9 0.4 0.22 11.9 0.4 1.6 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal MFS_1 PF07690.16 ETS88202.1 - 1.9e-38 132.3 50.6 1.9e-38 132.3 50.6 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily HET PF06985.11 ETS88205.1 - 6.4e-12 46.0 7.2 2.3e-10 41.0 1.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) CAP_N PF01213.19 ETS88206.1 - 0.18 11.3 4.6 0.24 10.9 4.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 ETS88206.1 - 0.21 11.7 4.5 0.3 11.1 4.5 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 ETS88206.1 - 0.24 11.4 0.9 0.29 11.2 0.9 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Ifi-6-16 PF06140.13 ETS88207.1 - 0.00022 21.0 26.6 0.00022 21.0 26.6 2.8 2 2 0 2 2 2 1 Interferon-induced 6-16 family Staph_haemo PF05480.11 ETS88207.1 - 0.00058 19.6 4.1 0.028 14.2 0.6 3.0 1 1 2 3 3 3 2 Staphylococcus haemolytic protein Mastoparan_2 PF08251.11 ETS88207.1 - 0.35 11.2 1.2 45 4.7 0.2 3.1 2 0 0 2 2 2 0 Mastoparan peptide HET PF06985.11 ETS88208.1 - 1.7e-15 57.7 6.8 1.8e-13 51.1 6.8 3.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MMR_HSR1 PF01926.23 ETS88209.1 - 1e-10 41.7 0.2 1.2e-09 38.3 0.0 2.7 2 1 1 3 3 3 1 50S ribosome-binding GTPase AIG1 PF04548.16 ETS88209.1 - 1.7e-08 34.0 0.0 1.7e-08 34.0 0.0 2.0 1 1 0 2 2 2 1 AIG1 family Septin PF00735.18 ETS88209.1 - 0.00022 20.6 1.0 0.00045 19.6 0.0 1.9 2 0 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 ETS88209.1 - 0.00071 19.5 0.1 0.00071 19.5 0.1 2.2 2 1 0 2 2 2 1 RsgA GTPase Ploopntkinase3 PF18751.1 ETS88209.1 - 0.00075 19.5 0.1 0.069 13.1 0.0 2.5 2 1 0 2 2 2 1 P-loop Nucleotide Kinase3 Dynamin_N PF00350.23 ETS88209.1 - 0.0024 17.9 13.2 0.22 11.6 0.0 3.5 2 2 1 3 3 3 2 Dynamin family ABC_tran PF00005.27 ETS88209.1 - 0.0095 16.4 7.7 0.32 11.5 7.8 2.6 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 ETS88209.1 - 0.015 15.0 0.0 0.076 12.8 0.0 2.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_17 PF13207.6 ETS88209.1 - 0.021 15.3 8.0 0.35 11.3 5.7 2.5 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 ETS88209.1 - 0.037 13.6 0.3 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.6 ETS88209.1 - 0.062 13.6 0.0 0.22 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain Uds1 PF15456.6 ETS88209.1 - 0.15 12.2 11.0 0.37 10.9 11.0 1.7 1 0 0 1 1 1 0 Up-regulated During Septation OmpH PF03938.14 ETS88209.1 - 0.47 10.8 22.5 0.84 10.0 22.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF87 PF01935.17 ETS88209.1 - 0.66 10.0 8.6 0.67 10.0 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_28 PF13521.6 ETS88209.1 - 0.71 10.1 0.0 0.71 10.1 0.0 3.3 2 1 0 2 2 1 0 AAA domain AAA_23 PF13476.6 ETS88209.1 - 1.1 9.8 0.0 1.1 9.8 0.0 2.6 2 1 0 2 2 1 0 AAA domain DUF4284 PF14112.6 ETS88209.1 - 1.1 10.2 4.9 1.7 9.6 4.0 1.7 1 1 0 1 1 1 0 Immunity protein 22 CENP-H PF05837.12 ETS88209.1 - 1.2 9.5 23.3 1.3 9.4 4.3 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) MeaB PF03308.16 ETS88209.1 - 2.1 7.2 7.1 1.9 7.4 0.1 2.5 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF755 PF05501.11 ETS88209.1 - 2.9 8.2 6.6 5.4 7.3 6.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF2652 PF10851.8 ETS88209.1 - 3.1 7.9 5.5 17 5.6 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2652) ALMT PF11744.8 ETS88209.1 - 7.6 5.2 7.7 10 4.8 7.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter HET PF06985.11 ETS88210.1 - 1e-22 81.0 0.0 1.8e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SMI1_KNR4 PF09346.10 ETS88210.1 - 0.063 13.7 0.0 0.61 10.5 0.1 2.1 1 1 1 2 2 2 0 SMI1 / KNR4 family (SUKH-1) Patatin PF01734.22 ETS88211.1 - 4.7e-14 53.1 0.0 1.2e-13 51.7 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase zf-B_box PF00643.24 ETS88211.1 - 0.0014 18.8 6.3 0.0014 18.8 6.3 2.7 3 0 0 3 3 2 1 B-box zinc finger ABC_tran PF00005.27 ETS88211.1 - 0.0038 17.7 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 ETS88211.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 ETS88211.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase TT1725 PF18324.1 ETS88211.1 - 0.055 13.6 0.4 14 5.8 0.2 2.5 2 0 0 2 2 2 0 Hypothetical protein TT1725 AAA_10 PF12846.7 ETS88211.1 - 0.064 12.2 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain BTG PF07742.12 ETS88211.1 - 0.09 12.6 0.1 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 BTG family MMR_HSR1 PF01926.23 ETS88211.1 - 0.13 12.4 0.1 0.53 10.4 0.1 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ETS88211.1 - 0.13 12.1 0.0 0.49 10.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 ETS88211.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 ETS88211.1 - 0.16 12.0 0.1 0.37 10.9 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain zf-C3HC4_3 PF13920.6 ETS88211.1 - 0.59 10.0 21.1 0.15 11.9 5.9 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ETS88211.1 - 0.75 10.2 21.7 0.044 14.1 5.8 2.7 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 ETS88211.1 - 0.93 9.4 21.5 4.1 7.3 6.1 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ETS88211.1 - 8.1 6.5 21.8 0.41 10.6 6.9 2.6 2 0 0 2 2 2 0 zinc-RING finger domain GLEYA PF10528.9 ETS88213.1 - 2.2e-27 95.3 0.8 2.2e-27 95.3 0.8 2.7 3 0 0 3 3 3 1 GLEYA domain PA14 PF07691.12 ETS88213.1 - 8e-05 22.5 0.0 0.00024 20.9 0.0 1.8 1 1 0 1 1 1 1 PA14 domain GMC_oxred_N PF00732.19 ETS88214.1 - 1e-61 209.0 0.0 1.3e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ETS88214.1 - 5.4e-38 130.8 0.2 1.2e-37 129.6 0.2 1.6 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 ETS88214.1 - 1.9e-05 24.8 0.1 6e-05 23.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ETS88214.1 - 2.1e-05 23.8 0.1 0.00077 18.6 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 ETS88214.1 - 2.4e-05 24.1 1.0 0.00028 20.6 1.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ETS88214.1 - 4.5e-05 22.8 0.0 9.9e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 ETS88214.1 - 8.5e-05 21.8 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ETS88214.1 - 0.00012 21.5 0.1 0.00048 19.5 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ETS88214.1 - 0.00097 18.5 0.1 0.25 10.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ETS88214.1 - 0.059 12.1 0.0 0.096 11.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF4038 PF13204.6 ETS88215.1 - 1.6e-82 277.7 2.5 2e-82 277.3 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Collagen_bind_2 PF12904.7 ETS88215.1 - 2.7e-20 72.1 0.0 6.3e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 Putative collagen-binding domain of a collagenase MFS_1 PF07690.16 ETS88216.1 - 1.3e-37 129.5 29.8 1.3e-37 129.5 29.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MWFE PF15879.5 ETS88216.1 - 0.087 13.0 0.1 0.82 9.9 0.0 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit C2 PF00168.30 ETS88217.1 - 2.6e-11 43.7 0.1 1e-10 41.8 0.0 1.9 2 0 0 2 2 2 1 C2 domain Presenilin PF01080.17 ETS88218.1 - 0.29 9.9 2.4 0.33 9.7 2.4 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 ETS88218.1 - 7.1 5.7 8.9 10 5.2 8.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Methyltransf_23 PF13489.6 ETS88219.1 - 2.2e-19 69.9 0.0 4.2e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ETS88219.1 - 3.4e-11 43.7 0.0 7.5e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ETS88219.1 - 2.5e-09 37.1 0.0 7.3e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ETS88219.1 - 3.1e-08 34.2 0.0 6.7e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ETS88219.1 - 7.8e-08 33.0 0.0 5.1e-07 30.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 ETS88219.1 - 0.00033 20.8 0.0 0.00056 20.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 ETS88219.1 - 0.0014 18.0 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 ETS88219.1 - 0.0028 17.0 0.0 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 ETS88219.1 - 0.0088 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 ETS88219.1 - 0.064 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase adh_short_C2 PF13561.6 ETS88220.1 - 6.4e-56 189.5 0.1 7.3e-56 189.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ETS88220.1 - 3.2e-48 163.8 0.1 3.8e-48 163.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ETS88220.1 - 1.3e-05 25.2 0.0 2.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ETS88220.1 - 2.3e-05 24.0 0.1 8.7e-05 22.1 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ETS88220.1 - 0.00019 20.9 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ETS88220.1 - 0.031 13.4 0.0 0.064 12.4 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Evr1_Alr PF04777.13 ETS88221.1 - 6.7e-25 87.5 0.0 1e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family AA_permease PF00324.21 ETS88221.1 - 0.14 10.7 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Amino acid permease APOBEC1 PF18769.1 ETS88221.1 - 0.19 12.0 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 APOBEC1 Proteasome PF00227.26 ETS88222.1 - 5.2e-49 166.3 0.2 6e-49 166.1 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.11 ETS88223.1 - 3.3e-40 138.1 1.6 4.6e-25 88.8 0.1 2.9 3 1 0 3 3 3 2 Cyclin DUF913 PF06025.12 ETS88223.1 - 0.61 9.0 0.0 0.61 9.0 0.0 2.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) MFS_1 PF07690.16 ETS88226.1 - 7.6e-28 97.4 66.5 9.2e-27 93.9 63.8 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ETS88226.1 - 9.5e-10 37.9 15.7 9.5e-10 37.9 15.7 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter Gram_pos_anchor PF00746.21 ETS88226.1 - 7.3 6.6 8.7 0.26 11.3 1.0 2.7 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Beta-lactamase PF00144.24 ETS88227.1 - 1.3e-33 116.6 0.8 2.3e-33 115.8 0.8 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 ETS88227.1 - 2.3e-10 40.9 0.0 4.2e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Delta_lysin PF05372.11 ETS88227.1 - 0.083 12.2 0.4 0.16 11.2 0.4 1.4 1 0 0 1 1 1 0 Delta lysin family p450 PF00067.22 ETS88230.1 - 2.9e-63 214.2 0.0 3.6e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 ETS88231.1 - 2.1e-26 92.6 0.0 3e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS88231.1 - 2.5e-14 53.4 0.0 3.4e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ETS88231.1 - 0.00054 19.5 0.0 0.025 14.0 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ETS88231.1 - 0.00062 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 KR domain RRM_1 PF00076.22 ETS88232.1 - 1.1e-07 31.5 0.0 0.0024 17.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Thioredoxin PF00085.20 ETS88234.1 - 8.4e-65 215.2 4.5 7.6e-32 109.4 0.1 3.9 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 ETS88234.1 - 9.4e-52 175.6 4.0 1.4e-38 132.6 0.6 3.5 2 2 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ETS88234.1 - 5e-12 46.0 0.2 0.0013 19.0 0.0 4.8 3 2 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.6 ETS88234.1 - 1.4e-10 41.2 0.1 0.00028 21.0 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like Calsequestrin PF01216.17 ETS88234.1 - 3.6e-10 39.5 0.8 3.6e-10 39.5 0.8 1.8 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_2 PF13098.6 ETS88234.1 - 1.3e-09 38.4 1.3 0.00012 22.5 0.0 3.2 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 ETS88234.1 - 3.4e-08 33.2 1.0 0.0059 16.0 0.0 2.7 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 ETS88234.1 - 1.5e-07 31.4 1.7 0.0051 16.7 0.1 3.4 3 1 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 ETS88234.1 - 5.6e-07 29.4 3.0 0.008 15.9 0.0 3.4 3 0 0 3 3 3 2 Redoxin ERp29_N PF07912.13 ETS88234.1 - 0.00051 20.2 0.9 1.1 9.4 0.0 3.8 3 2 0 3 3 3 1 ERp29, N-terminal domain DSBA PF01323.20 ETS88234.1 - 0.0063 16.3 0.2 18 5.1 0.0 4.0 3 1 0 3 3 3 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 ETS88234.1 - 0.009 16.0 0.8 0.044 13.8 0.1 2.5 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_4 PF13462.6 ETS88234.1 - 0.096 12.8 2.6 17 5.6 0.1 3.9 3 2 0 3 3 3 0 Thioredoxin Amidohydro_1 PF01979.20 ETS88235.1 - 3.2e-33 115.5 0.1 3.8e-33 115.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ETS88235.1 - 2.2e-09 37.3 1.2 1.6e-07 31.2 0.1 2.3 2 1 0 2 2 2 2 Amidohydrolase family Mon1 PF03164.14 ETS88237.1 - 2.8e-152 507.5 0.0 3.2e-152 507.3 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Dopey_N PF04118.14 ETS88238.1 - 2.1e-119 398.2 0.3 3.7e-118 394.1 0.0 2.6 2 0 0 2 2 2 1 Dopey, N-terminal DUF4681 PF15732.5 ETS88238.1 - 0.19 12.0 0.0 0.52 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4681) S1-P1_nuclease PF02265.16 ETS88239.1 - 0.065 13.0 2.4 0.14 11.9 1.9 1.6 1 1 1 2 2 2 0 S1/P1 Nuclease Methyltransf_15 PF09445.10 ETS88240.1 - 6e-39 133.3 0.0 7.9e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 ETS88240.1 - 3e-06 27.1 0.0 4.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 ETS88240.1 - 0.00064 19.4 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_3 PF01596.17 ETS88240.1 - 0.0077 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase UPF0020 PF01170.18 ETS88240.1 - 0.026 14.2 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 RrnaAD PF00398.20 ETS88240.1 - 0.041 13.0 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 ETS88240.1 - 0.054 14.2 0.0 0.1 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 ETS88240.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain GRASP55_65 PF04495.14 ETS88241.1 - 5.1e-44 149.9 0.0 4.6e-43 146.8 0.0 2.0 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 ETS88241.1 - 0.021 14.6 0.0 9.2 6.2 0.0 2.4 2 0 0 2 2 2 0 PDZ domain DAD PF02109.16 ETS88242.1 - 3.5e-49 165.7 2.0 4.3e-49 165.4 2.0 1.1 1 0 0 1 1 1 1 DAD family RDD PF06271.12 ETS88242.1 - 0.045 14.0 0.2 0.074 13.3 0.2 1.4 1 0 0 1 1 1 0 RDD family S1FA PF04689.13 ETS88242.1 - 0.94 9.7 2.2 17 5.7 0.4 2.4 2 0 0 2 2 2 0 DNA binding protein S1FA Tmemb_14 PF03647.13 ETS88243.1 - 2.5e-20 73.0 7.5 2.8e-20 72.8 7.5 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Cmc1 PF08583.10 ETS88244.1 - 1.1e-14 54.1 3.9 1.1e-14 54.1 3.9 1.6 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.8 ETS88244.1 - 1.1 9.7 4.5 3.8 8.0 4.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Prefoldin_2 PF01920.20 ETS88245.1 - 9.4e-27 93.1 7.0 1.1e-26 92.9 7.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit ALIX_LYPXL_bnd PF13949.6 ETS88245.1 - 0.0003 20.2 1.3 0.00037 19.9 1.3 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF4757 PF15949.5 ETS88245.1 - 0.0041 17.6 1.5 0.0063 17.0 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4757) Prefoldin PF02996.17 ETS88245.1 - 0.013 15.4 5.3 1.4 8.9 5.3 2.2 1 1 0 1 1 1 0 Prefoldin subunit DUF2205 PF10224.9 ETS88245.1 - 0.024 14.6 5.8 0.038 14.0 0.8 2.1 2 0 0 2 2 2 0 Short coiled-coil protein Wtap PF17098.5 ETS88245.1 - 0.035 14.1 1.8 2.6 7.9 0.1 2.0 2 0 0 2 2 2 0 WTAP/Mum2p family CLZ PF16526.5 ETS88245.1 - 0.055 13.8 2.8 2.4 8.6 0.1 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ZnuA PF01297.17 ETS88245.1 - 0.056 12.9 2.1 0.89 8.9 0.3 2.0 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic OmpH PF03938.14 ETS88245.1 - 0.074 13.4 7.8 0.83 10.0 1.2 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TMF_DNA_bd PF12329.8 ETS88245.1 - 3.9 7.6 10.3 0.31 11.1 1.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CBFD_NFYB_HMF PF00808.23 ETS88246.1 - 1.3e-25 89.5 1.2 2.3e-25 88.7 1.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ETS88246.1 - 1.7e-06 28.4 0.1 3.4e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 ETS88246.1 - 0.0017 18.3 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 ETS88246.1 - 0.0028 17.6 0.0 0.0042 17.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 ETS88246.1 - 0.047 13.8 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold SIKE PF05769.11 ETS88246.1 - 0.11 12.4 0.3 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 SIKE family TFIID_20kDa PF03847.13 ETS88246.1 - 0.12 12.8 0.1 0.23 12.0 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A RRN3 PF05327.11 ETS88247.1 - 7e-169 563.0 0.3 7e-169 563.0 0.3 1.9 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 DUF2205 PF10224.9 ETS88248.1 - 0.036 14.1 2.5 18 5.4 0.0 2.4 2 0 0 2 2 2 0 Short coiled-coil protein bZIP_1 PF00170.21 ETS88248.1 - 0.072 13.2 14.3 0.42 10.7 14.3 2.0 1 1 0 1 1 1 0 bZIP transcription factor CENP-H PF05837.12 ETS88248.1 - 0.074 13.5 6.1 0.12 12.7 6.1 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 ETS88248.1 - 0.42 10.8 3.8 0.7 10.1 3.8 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family YabA PF06156.13 ETS88248.1 - 0.58 10.8 3.5 1.1 9.9 2.8 1.8 1 1 0 1 1 1 0 Initiation control protein YabA Spc7 PF08317.11 ETS88248.1 - 0.62 8.9 7.2 0.87 8.4 7.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Metal_resist PF13801.6 ETS88248.1 - 3 8.1 12.8 2.5 8.3 11.1 1.7 2 0 0 2 2 2 0 Heavy-metal resistance TraV PF09676.10 ETS88248.1 - 8.7 7.3 8.6 26 5.8 8.6 1.8 1 1 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) DUF3500 PF12006.8 ETS88249.1 - 6.2e-109 364.0 0.0 7.4e-109 363.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) DUF2914 PF11141.8 ETS88249.1 - 0.069 12.9 0.0 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2914) IU_nuc_hydro PF01156.19 ETS88250.1 - 1.6e-35 123.2 0.1 1.9e-35 122.9 0.1 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase NACHT PF05729.12 ETS88251.1 - 4.5e-07 29.9 1.0 2.2e-05 24.5 0.3 2.9 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 ETS88251.1 - 4.9e-06 27.0 0.2 0.0001 22.7 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ETS88251.1 - 0.0005 20.4 0.5 0.0084 16.4 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 ETS88251.1 - 0.00096 18.9 0.0 0.019 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 ETS88251.1 - 0.0012 19.4 0.0 0.0062 17.1 0.0 2.2 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 ETS88251.1 - 0.0033 18.0 4.5 0.028 14.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 ETS88251.1 - 0.0067 15.6 0.0 0.017 14.3 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain SesA PF17107.5 ETS88251.1 - 0.013 15.6 0.2 0.038 14.2 0.1 1.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_29 PF13555.6 ETS88251.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 ETS88251.1 - 0.095 12.8 2.3 0.24 11.5 0.0 2.5 2 1 0 2 2 2 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 ETS88251.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 ETS88251.1 - 0.12 12.7 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 ETS88251.1 - 0.13 12.4 0.0 0.47 10.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 ETS88251.1 - 0.16 12.4 0.6 6.6 7.2 0.1 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CFEM PF05730.11 ETS88252.1 - 2.2e-12 46.9 11.7 4e-12 46.1 11.7 1.4 1 0 0 1 1 1 1 CFEM domain AMP-binding PF00501.28 ETS88253.1 - 1.7e-73 247.6 0.0 3.5e-73 246.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ETS88253.1 - 7.9e-60 202.2 0.0 1.7e-59 201.1 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 ETS88253.1 - 8.1e-51 172.3 1.8 1.8e-50 171.1 1.8 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ETS88253.1 - 4.7e-39 134.3 1.8 1.2e-38 133.0 1.8 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ETS88253.1 - 1.1e-22 80.7 0.4 5.6e-12 45.6 0.0 3.7 2 2 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 ETS88253.1 - 7.5e-17 61.8 4.2 1.4e-14 54.4 1.2 2.5 2 0 0 2 2 2 2 KR domain PP-binding PF00550.25 ETS88253.1 - 1.8e-12 47.4 0.0 4.8e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 ETS88253.1 - 5.4e-08 32.9 1.8 1.2e-07 31.8 0.6 2.3 3 0 0 3 3 3 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ETS88253.1 - 9.6e-08 31.5 0.7 0.00089 18.4 0.0 2.6 2 1 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.19 ETS88253.1 - 1.1e-06 27.9 0.0 0.0056 15.7 0.0 2.5 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ETS88253.1 - 1.4e-06 27.7 1.2 0.00064 18.9 0.2 3.1 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ETS88253.1 - 0.00012 21.7 0.2 0.074 12.4 0.0 2.8 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ETS88253.1 - 0.0015 18.1 2.5 0.13 11.8 1.1 3.1 3 0 0 3 3 3 1 NmrA-like family THF_DHG_CYH_C PF02882.19 ETS88253.1 - 0.0044 16.3 0.2 0.013 14.8 0.2 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.15 ETS88253.1 - 0.031 14.1 1.7 0.087 12.6 0.6 2.1 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein AMP-binding_C PF13193.6 ETS88253.1 - 0.041 14.9 0.3 1.6 9.8 0.0 3.3 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain Wax2_C PF12076.8 ETS88253.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 WAX2 C-terminal domain Acetyltransf_1 PF00583.25 ETS88254.1 - 3.9e-17 62.6 0.0 5.2e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ETS88254.1 - 4.3e-15 55.8 0.1 6.8e-15 55.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ETS88254.1 - 5.6e-12 45.9 0.1 8.4e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ETS88254.1 - 7.5e-08 32.7 0.0 1.1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ETS88254.1 - 1.2e-07 31.5 0.1 2.5e-07 30.6 0.1 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 ETS88254.1 - 1.7e-05 24.8 0.1 3.3e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 ETS88254.1 - 2.1e-05 25.2 0.0 2.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ETS88254.1 - 0.0041 17.2 0.0 0.0055 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ETS88254.1 - 0.021 14.5 0.0 0.03 14.0 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Abhydrolase_1 PF00561.20 ETS88255.1 - 5.2e-05 23.0 0.0 0.0045 16.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ETS88255.1 - 0.0001 23.0 0.0 0.00012 22.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ETS88255.1 - 0.042 13.1 0.0 0.064 12.5 0.0 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 FAR1 PF03101.15 ETS88257.1 - 0.0032 18.1 0.1 0.0059 17.3 0.1 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain Ammonium_transp PF00909.21 ETS88258.1 - 2.4e-69 234.0 21.9 2.8e-69 233.7 21.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF1345 PF07077.11 ETS88258.1 - 0.085 12.6 4.0 3.4 7.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) ThrE PF06738.12 ETS88258.1 - 1.5 8.2 8.5 13 5.1 8.5 2.5 1 1 0 1 1 1 0 Putative threonine/serine exporter Fungal_trans_2 PF11951.8 ETS88259.1 - 2.6e-14 52.8 0.3 2.1e-10 40.0 0.5 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.16 ETS88260.1 - 1.4e-37 129.4 24.1 2e-37 129.0 24.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DPM3 PF08285.11 ETS88260.1 - 1.9 8.7 4.6 4.5 7.5 3.9 2.0 1 1 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Abhydrolase_3 PF07859.13 ETS88261.1 - 1.3e-55 188.6 0.0 1.5e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ETS88261.1 - 3.3e-08 33.3 0.0 4.9e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 ETS88261.1 - 7e-07 28.5 0.4 2.2e-06 26.9 0.4 1.6 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 ETS88261.1 - 7.1e-05 22.5 0.0 0.0073 15.9 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 ETS88261.1 - 0.0021 17.4 0.0 0.031 13.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ETS88261.1 - 0.0093 16.6 2.5 0.016 15.8 2.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 ETS88261.1 - 0.022 14.3 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 ETS88261.1 - 0.026 13.2 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) AATase PF07247.12 ETS88262.1 - 2.1e-08 33.2 0.0 6.2e-08 31.6 0.0 1.7 2 0 0 2 2 2 1 Alcohol acetyltransferase EF-hand_13 PF17958.1 ETS88262.1 - 0.052 13.3 0.0 6.1 6.7 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain DUF3445 PF11927.8 ETS88263.1 - 1.8e-70 237.1 0.0 2e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF604 PF04646.12 ETS88266.1 - 4.2e-10 39.5 0.0 7.5e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 ETS88266.1 - 0.00011 21.7 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 Fringe-like DUF3958 PF13125.6 ETS88267.1 - 0.81 9.9 16.4 0.68 10.2 4.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3958) Glyco_transf_90 PF05686.12 ETS88268.1 - 2.1e-16 59.9 0.4 9.1e-12 44.6 0.0 3.6 3 1 0 3 3 3 3 Glycosyl transferase family 90 Cpn60_TCP1 PF00118.24 ETS88269.1 - 1.7e-140 468.9 14.3 1.9e-140 468.8 14.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 ETS88269.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat eIF2A PF08662.11 ETS88270.1 - 1.6e-33 116.2 5.5 4.4e-33 114.8 1.0 3.5 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 ETS88270.1 - 5.7e-05 22.9 0.0 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 ETS88270.1 - 0.036 14.9 0.3 2.6 9.1 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat RabGAP-TBC PF00566.18 ETS88273.1 - 6e-33 114.3 0.0 9.9e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 ETS88273.1 - 3.6e-08 32.2 0.5 3.6e-08 32.2 0.5 1.8 2 0 0 2 2 2 1 SBE2, cell-wall formation FA_desaturase PF00487.24 ETS88277.1 - 1.2e-23 84.3 14.6 2.7e-23 83.1 14.6 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 ETS88277.1 - 2.1e-06 28.0 0.0 7.4e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) Git3 PF11710.8 ETS88279.1 - 2.1e-15 57.1 9.1 8.3e-15 55.1 9.1 2.0 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 ETS88279.1 - 4.3e-09 36.1 0.7 5.7e-09 35.7 0.2 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF4064 PF13273.6 ETS88279.1 - 0.00074 19.8 1.6 3 8.2 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF4064) Dicty_CAR PF05462.11 ETS88279.1 - 0.0018 17.4 4.1 0.0038 16.4 4.1 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 ETS88279.1 - 0.0035 17.4 0.3 0.011 15.8 0.3 1.8 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Pkinase PF00069.25 ETS88280.1 - 1.5e-41 142.5 0.0 3.7e-40 137.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 ETS88280.1 - 8.6e-38 129.4 0.0 1.5e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 ETS88280.1 - 7.2e-21 74.6 0.0 8.4e-20 71.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 ETS88280.1 - 0.00037 20.3 0.6 0.22 11.5 0.0 3.6 3 0 0 3 3 3 1 PQQ enzyme repeat Kdo PF06293.14 ETS88280.1 - 0.0011 18.4 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ETS88280.1 - 0.0033 16.3 0.1 0.0095 14.7 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase PQQ_2 PF13360.6 ETS88280.1 - 0.015 14.9 0.1 0.18 11.4 0.1 2.5 2 1 0 2 2 2 0 PQQ-like domain APH PF01636.23 ETS88280.1 - 0.019 14.9 0.9 0.042 13.8 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family PQQ_3 PF13570.6 ETS88280.1 - 0.09 13.3 0.0 77 4.0 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain YrbL-PhoP_reg PF10707.9 ETS88280.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SWIB PF02201.18 ETS88281.1 - 5.2e-31 106.4 0.2 1.4e-30 105.0 0.1 1.8 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 ETS88281.1 - 3.6e-15 55.6 1.1 4e-14 52.3 0.9 2.2 2 0 0 2 2 2 1 DEK C terminal domain Macoilin PF09726.9 ETS88281.1 - 0.24 9.9 1.9 0.26 9.8 1.9 1.1 1 0 0 1 1 1 0 Macoilin family API5 PF05918.11 ETS88281.1 - 0.35 9.6 3.8 0.52 9.1 3.8 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zf-C3HC4_3 PF13920.6 ETS88282.1 - 2.4e-05 24.1 10.2 2.4e-05 24.1 10.2 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ETS88282.1 - 5.9 6.8 22.0 0.11 12.4 11.4 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Pestalotiopsis_fici_W106-1-PFICI/GCA_000516985.1_PFICI_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Pestalotiopsis_fici_W106-1-PFICI/GCA_000516985.1_PFICI_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Pestalotiopsis_fici_W106-1-PFICI/GCA_000516985.1_PFICI_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Pestalotiopsis_fici_W106-1-PFICI/GCA_000516985.1_PFICI_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 03:47:06 2019 # [ok]